## Sat Nov  9 18:06:42 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS3_bin.128.fa -m mmseqs --itype genome -o CMS3_bin.128 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS3_bin.128 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS3_k127_1000937_5	1123368.AUIS01000004_gene281	2.098e-95	336.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Iron Permease	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
CMS3_k127_1000937_17	448385.sce7135	1.576e-26	123.0	COG5502@1|root,COG5502@2|Bacteria,1QAI7@1224|Proteobacteria,4353X@68525|delta/epsilon subdivisions,2X954@28221|Deltaproteobacteria,2Z1ZQ@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
CMS3_k127_1000937_15	502025.Hoch_5065	1.572e-29	128.0	COG5622@1|root,COG5622@2|Bacteria,1NPM6@1224|Proteobacteria,432SF@68525|delta/epsilon subdivisions,2WXUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM Host attachment protein	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS3_k127_1000937_1	502025.Hoch_5019	8.545e-176	563.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2YU57@29|Myxococcales	28221|Deltaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_1000937_2	502025.Hoch_5020	1.223e-126	438.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2YUI8@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS3_k127_1000937_7	1173028.ANKO01000170_gene3367	6.584e-94	313.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,1H7AV@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS3_k127_1000937_9	1089552.KI911559_gene1015	1.437e-88	301.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,2JP9M@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_1000937_18	1192034.CAP_5656	5.693e-19	98.0	COG0515@1|root,COG0515@2|Bacteria,1Q7S0@1224|Proteobacteria,432FP@68525|delta/epsilon subdivisions,2WYAW@28221|Deltaproteobacteria,2Z2N3@29|Myxococcales	28221|Deltaproteobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
CMS3_k127_1000937_19	439235.Dalk_0288	3.146e-18	101.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria,2MKSB@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Outer membrane protein transport protein (OMPP1 FadL TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_1000937_0	502025.Hoch_4998	7.638e-282	878.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,2YX6Q@29|Myxococcales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS3_k127_1000937_4	502025.Hoch_4641	3.481e-102	340.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2YVHZ@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS3_k127_1000937_6	502025.Hoch_4642	5.868e-95	317.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
CMS3_k127_1000937_10	502025.Hoch_4646	1.556e-72	256.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WQAR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2,Peptidase_M1
CMS3_k127_1000937_8	502025.Hoch_4647	6.251e-92	312.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,2YUZJ@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS3_k127_1000937_11	502025.Hoch_4648	3.476e-70	244.0	COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,43BH4@68525|delta/epsilon subdivisions,2WRU4@28221|Deltaproteobacteria,2YVB3@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_1000937_16	502025.Hoch_4649	2.173e-29	133.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2WRCE@28221|Deltaproteobacteria,2YZ6J@29|Myxococcales	28221|Deltaproteobacteria	U	ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_1000937_14	502025.Hoch_4650	1.734e-30	136.0	COG0810@1|root,COG0810@2|Bacteria,1NFMG@1224|Proteobacteria,42UAW@68525|delta/epsilon subdivisions,2WTBZ@28221|Deltaproteobacteria,2Z1UD@29|Myxococcales	28221|Deltaproteobacteria	M	Ferric siderophore transporter, periplasmic energy transduction protein TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_1000937_20	696747.NIES39_Q02210	9.094e-11	75.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1GQZ6@1117|Cyanobacteria,1H9P5@1150|Oscillatoriales	1117|Cyanobacteria	Q	Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PPC
CMS3_k127_1000937_13	215803.DB30_2010	1.249e-33	148.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YYU3@29|Myxococcales	28221|Deltaproteobacteria	S	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PQQ_2,VCBS
CMS3_k127_1000937_3	502025.Hoch_4651	1.726e-107	363.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K16191,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6.1.3	-	-	BON,Gram_pos_anchor,OmpA,TSP_3
CMS3_k127_1006703_0	1122604.JONR01000039_gene3772	3.431e-31	140.0	COG2132@1|root,COG4409@1|root,COG2132@2|Bacteria,COG4409@2|Bacteria,1PHJD@1224|Proteobacteria,1T8MC@1236|Gammaproteobacteria,1XAXM@135614|Xanthomonadales	135614|Xanthomonadales	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1010214_3	502025.Hoch_6806	2.817e-55	213.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WNYG@28221|Deltaproteobacteria,2Z1BJ@29|Myxococcales	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS3_k127_1010214_4	1242864.D187_008787	1.624e-22	109.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K21009	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	GAF_3,GGDEF,PAS_4,Response_reg
CMS3_k127_1010214_1	502025.Hoch_6807	8.013e-149	484.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YV21@29|Myxococcales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS3_k127_1010214_0	502025.Hoch_6809	1.726e-219	692.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2YUIX@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS3_k127_1011343_12	1223545.GS4_07_00360	1.724e-09	68.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4GBH3@85026|Gordoniaceae	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
CMS3_k127_1011343_8	251221.35212131	3.216e-41	159.0	2AVYW@1|root,31MT4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1011343_10	1265507.KB899637_gene476	1.353e-27	131.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y5XC@135624|Aeromonadales	1236|Gammaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS3_k127_1011343_5	502025.Hoch_3687	7.928e-91	330.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
CMS3_k127_1011343_3	502025.Hoch_3686	1.577e-105	349.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2YXBS@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
CMS3_k127_1011343_0	502025.Hoch_3685	4.282e-234	754.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_1011343_6	1144275.COCOR_05162	4.253e-64	237.0	COG0508@1|root,COG0515@1|root,COG0508@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	pkn7	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_1011343_2	502025.Hoch_3683	3.322e-109	381.0	COG2720@1|root,COG2720@2|Bacteria,1NG7U@1224|Proteobacteria,4319R@68525|delta/epsilon subdivisions,2WW7C@28221|Deltaproteobacteria,2YWZH@29|Myxococcales	28221|Deltaproteobacteria	V	vancomycin resistance protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,VanW
CMS3_k127_1011343_4	502025.Hoch_3681	1.307e-98	343.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1011343_9	1089549.AZUQ01000001_gene665	8.288e-30	136.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4EY9U@85014|Glycomycetales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_1011343_1	502025.Hoch_3679	2.399e-182	598.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2YUW7@29|Myxococcales	28221|Deltaproteobacteria	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
CMS3_k127_1048055_1	502025.Hoch_1456	5.459e-74	254.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z3I1@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
CMS3_k127_1048055_0	749927.AMED_8866	4.625e-137	454.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4E0TN@85010|Pseudonocardiales	201174|Actinobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_1053958_3	502025.Hoch_3779	2.016e-87	294.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2YWMX@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1716	ECH_1
CMS3_k127_1053958_0	502025.Hoch_3778	6.381e-180	569.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1053958_1	502025.Hoch_3775	1.06e-146	480.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YU5D@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1053958_4	448385.sce1655	5.512e-53	206.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,2YV7A@29|Myxococcales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CMS3_k127_1053958_6	502025.Hoch_3773	2.075e-46	186.0	COG0662@1|root,COG0662@2|Bacteria,1QX8I@1224|Proteobacteria,43C1N@68525|delta/epsilon subdivisions,2WSZJ@28221|Deltaproteobacteria,2YVVW@29|Myxococcales	28221|Deltaproteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_1053958_2	502025.Hoch_3772	1.752e-122	421.0	COG1703@1|root,COG1703@2|Bacteria,1R44P@1224|Proteobacteria,43B1C@68525|delta/epsilon subdivisions,2X6FJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_1065989_3	391625.PPSIR1_25861	3.123e-128	423.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS3_k127_1065989_1	502025.Hoch_2608	3.88e-237	764.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_1065989_4	502025.Hoch_2607	2.126e-87	298.0	COG3031@1|root,COG3031@2|Bacteria,1NB50@1224|Proteobacteria,42WPG@68525|delta/epsilon subdivisions,2WREX@28221|Deltaproteobacteria,2YVJ9@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CMS3_k127_1065989_2	502025.Hoch_2606	2.008e-215	678.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJU@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_1065989_0	502025.Hoch_2389	5.6e-290	915.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,439XR@68525|delta/epsilon subdivisions,2WVH6@28221|Deltaproteobacteria,2Z0UX@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_1065989_5	502025.Hoch_2388	1.662e-26	124.0	2AYUN@1|root,31R03@2|Bacteria,1QNIW@1224|Proteobacteria,43861@68525|delta/epsilon subdivisions,2X3FV@28221|Deltaproteobacteria,2YVX4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1076565_1	502025.Hoch_5311	1.955e-75	261.0	COG1994@1|root,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42R1V@68525|delta/epsilon subdivisions,2WN7S@28221|Deltaproteobacteria,2YVUM@29|Myxococcales	28221|Deltaproteobacteria	K	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
CMS3_k127_1076565_5	290315.Clim_1497	0.0002339	51.0	2C6P2@1|root,33C1K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS3_k127_1076565_3	234267.Acid_4252	5.044e-29	130.0	COG0613@1|root,COG0613@2|Bacteria,3Y2US@57723|Acidobacteria	57723|Acidobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1076565_0	3656.XP_008467318.1	2.852e-174	555.0	COG0334@1|root,KOG2250@2759|Eukaryota,37Q3I@33090|Viridiplantae,3GC9F@35493|Streptophyta,4JRW9@91835|fabids	35493|Streptophyta	E	Belongs to the Glu Leu Phe Val dehydrogenases family	GDH2	GO:0000166,GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0005774,GO:0006950,GO:0006970,GO:0006995,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009267,GO:0009268,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010446,GO:0016020,GO:0016491,GO:0016638,GO:0016639,GO:0017076,GO:0030554,GO:0031090,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0035639,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0051716,GO:0055114,GO:0071496,GO:0097159,GO:0097367,GO:0098588,GO:0098805,GO:1901265,GO:1901363	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_1076565_2	1192034.CAP_2606	3.106e-56	213.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_2606|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1076584_17	502025.Hoch_2512	0.0001454	46.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1076584_7	502025.Hoch_5619	2.653e-70	251.0	COG2214@1|root,COG2214@2|Bacteria,1Q9VY@1224|Proteobacteria,434N0@68525|delta/epsilon subdivisions,2WYZE@28221|Deltaproteobacteria,2Z0ZT@29|Myxococcales	28221|Deltaproteobacteria	O	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_1076584_16	1382306.JNIM01000001_gene1791	1.028e-09	62.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	XAC3035	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06191	-	-	-	-	ko00000	-	-	-	DUF836,Glutaredoxin
CMS3_k127_1076584_9	502025.Hoch_5620	1.649e-54	199.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2X2EG@28221|Deltaproteobacteria,2Z20T@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1076584_13	1238190.AMQY01000014_gene920	3.458e-27	115.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_1076584_3	502025.Hoch_5621	4.466e-117	389.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,42Q6E@68525|delta/epsilon subdivisions,2X5QA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Cobalamin	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
CMS3_k127_1076584_11	502025.Hoch_5622	9.464e-37	147.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HAMP,HATPase_c,HATPase_c_2,HWE_HK,HisKA_2,PAS,PAS_3,PAS_4,dCache_1
CMS3_k127_1076584_0	502025.Hoch_5623	0.0	1143.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria,2YUP3@29|Myxococcales	28221|Deltaproteobacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
CMS3_k127_1076584_4	211165.AJLN01000137_gene1510	8.029e-93	324.0	COG0654@1|root,COG0654@2|Bacteria,1G5VZ@1117|Cyanobacteria,1JII7@1189|Stigonemataceae	1117|Cyanobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_1076584_12	237368.SCABRO_00164	1.125e-34	150.0	COG2114@1|root,COG2114@2|Bacteria,2J38V@203682|Planctomycetes	203682|Planctomycetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_1076584_1	502025.Hoch_2761	1.575e-223	710.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2YY2C@29|Myxococcales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS3_k127_1076584_14	639282.DEFDS_1053	1.977e-25	108.0	COG1925@1|root,COG1925@2|Bacteria,2GG2N@200930|Deferribacteres	200930|Deferribacteres	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS3_k127_1076584_6	502025.Hoch_2759	1.213e-87	298.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2YV1E@29|Myxococcales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS3_k127_1076584_2	502025.Hoch_2758	4.026e-134	434.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CMS3_k127_1076584_8	502025.Hoch_2757	1.133e-56	209.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2YVHR@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS3_k127_1076584_10	502025.Hoch_2756	7.934e-53	190.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,2Z15W@29|Myxococcales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
CMS3_k127_1111977_2	1192034.CAP_3735	9.465e-68	241.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1111977_0	502025.Hoch_0085	5.097e-162	526.0	COG0492@1|root,COG1146@1|root,COG3266@1|root,COG0492@2|Bacteria,COG1146@2|Bacteria,COG3266@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
CMS3_k127_1111977_1	502025.Hoch_1459	2.428e-124	416.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2WM5N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1121509_21	448385.sce7744	3.359e-05	51.0	COG3266@1|root,COG3266@2|Bacteria,1QA9E@1224|Proteobacteria,434X4@68525|delta/epsilon subdivisions,2WZ81@28221|Deltaproteobacteria,2Z1J2@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121509_13	1254432.SCE1572_02320	1.362e-47	184.0	COG1595@1|root,COG1595@2|Bacteria,1QR72@1224|Proteobacteria,43E0Y@68525|delta/epsilon subdivisions,2WZDM@28221|Deltaproteobacteria,2Z1WN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1121509_18	391625.PPSIR1_29158	6.62e-13	81.0	2DK48@1|root,308EE@2|Bacteria,1QSG3@1224|Proteobacteria,4357G@68525|delta/epsilon subdivisions,2WZIH@28221|Deltaproteobacteria,2Z27V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121509_9	502025.Hoch_0246	6.618e-78	277.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121509_11	502025.Hoch_0246	1.791e-75	271.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121509_1	502025.Hoch_0411	2.26e-312	980.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
CMS3_k127_1121509_6	502025.Hoch_0409	1.425e-96	327.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,42YKX@68525|delta/epsilon subdivisions,2WTZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_1121509_12	324602.Caur_2455	6.139e-71	247.0	COG2162@1|root,COG2162@2|Bacteria,2G8H7@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
CMS3_k127_1121509_3	502025.Hoch_5836	4.322e-145	471.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YXC1@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_1121509_19	768671.ThimaDRAFT_4411	2.918e-12	70.0	COG3062@1|root,COG3062@2|Bacteria,1PUNN@1224|Proteobacteria,1TKDR@1236|Gammaproteobacteria,1X21U@135613|Chromatiales	135613|Chromatiales	P	NapD protein	-	-	-	ko:K02570	-	-	-	-	ko00000	-	-	-	NapD
CMS3_k127_1121509_0	768671.ThimaDRAFT_4410	0.0	1233.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WW7D@135613|Chromatiales	135613|Chromatiales	C	Molybdopterin oxidoreductase Fe4S4 domain	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1121509_16	1002804.HBZC1_04310	7.794e-26	115.0	COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	napB	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
CMS3_k127_1121509_5	502025.Hoch_0055	1.449e-111	375.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.71	ko:K01346	ko04972,ko04974,map04972,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Trypsin
CMS3_k127_1121509_8	502025.Hoch_4069	9.875e-81	279.0	COG0664@1|root,COG0664@2|Bacteria,1Q9MI@1224|Proteobacteria,43DTH@68525|delta/epsilon subdivisions,2WYU5@28221|Deltaproteobacteria,2Z0MC@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_1121509_15	1254432.SCE1572_37345	9.485e-42	160.0	COG0764@1|root,COG0764@2|Bacteria,1QSTA@1224|Proteobacteria,4355J@68525|delta/epsilon subdivisions,2X9PY@28221|Deltaproteobacteria,2Z23M@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121509_20	1392498.JQLH01000001_gene1357	6.913e-08	66.0	COG1361@1|root,COG2373@1|root,COG2885@1|root,COG2911@1|root,COG4932@1|root,COG5384@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2885@2|Bacteria,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5384@2|Bacteria,4NS01@976|Bacteroidetes,1I3QG@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C
CMS3_k127_1121509_17	871968.DESME_03075	1.03e-19	104.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_1121509_7	404589.Anae109_2071	7.792e-90	320.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121509_10	344747.PM8797T_06687	1.131e-76	266.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS3_k127_1121509_2	502025.Hoch_1816	3.045e-157	501.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS3_k127_1121509_14	1192034.CAP_5278	1.42e-47	186.0	COG1357@1|root,COG1357@2|Bacteria,1RJ94@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1121509_4	502025.Hoch_5960	2.886e-114	376.0	COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YUHG@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_112289_3	643648.Slip_0071	6.811e-181	597.0	COG0507@1|root,COG1112@1|root,COG2852@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2852@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia,42KV6@68298|Syntrophomonadaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559
CMS3_k127_112289_15	1144275.COCOR_03484	8.403e-79	287.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,PEGA,Pkinase
CMS3_k127_112289_1	502025.Hoch_4573	5.322e-208	709.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
CMS3_k127_112289_12	502025.Hoch_3956	2.869e-93	322.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_112289_13	448385.sce9021	1.811e-86	295.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,Acyl_transf_1,GSDH,KR,Ketoacyl-synt_C,PS-DH,Recombinase,Resolvase,Zn_ribbon_recom,ketoacyl-synt
CMS3_k127_112289_0	502025.Hoch_6440	0.0	1537.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2X7WN@28221|Deltaproteobacteria,2YXQ6@29|Myxococcales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS3_k127_112289_16	502025.Hoch_5385	2.615e-76	263.0	COG3295@1|root,COG3295@2|Bacteria,1RFI2@1224|Proteobacteria,42XJC@68525|delta/epsilon subdivisions,2WSKA@28221|Deltaproteobacteria,2Z0VD@29|Myxococcales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM_like_2
CMS3_k127_112289_10	502025.Hoch_5386	9.353e-99	327.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,43AZC@68525|delta/epsilon subdivisions,2WPPS@28221|Deltaproteobacteria,2YZRW@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS3_k127_112289_18	391625.PPSIR1_02641	1.937e-60	231.0	COG1028@1|root,COG1028@2|Bacteria,1N8G3@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_112289_11	765952.PUV_00830	5.035e-98	334.0	COG0861@1|root,COG0861@2|Bacteria,2JGY6@204428|Chlamydiae	204428|Chlamydiae	P	Integral membrane protein TerC family	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CMS3_k127_112289_4	502025.Hoch_5389	1.194e-171	550.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YWP2@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS3_k127_112289_27	1242864.D187_006227	2.843e-14	86.0	COG2730@1|root,COG4447@1|root,COG2730@2|Bacteria,COG4447@2|Bacteria,1R5GC@1224|Proteobacteria,434P8@68525|delta/epsilon subdivisions,2WZ0H@28221|Deltaproteobacteria,2Z12C@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CMS3_k127_112289_22	448385.sce1024	1.99e-39	166.0	COG2863@1|root,COG2863@2|Bacteria,1NDS5@1224|Proteobacteria,43CTZ@68525|delta/epsilon subdivisions,2X81J@28221|Deltaproteobacteria,2YVKA@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_112289_24	391625.PPSIR1_19664	2.916e-30	132.0	COG1470@1|root,COG1470@2|Bacteria,1Q21G@1224|Proteobacteria,437PA@68525|delta/epsilon subdivisions,2X2XJ@28221|Deltaproteobacteria,2YX5A@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_112289_28	1278073.MYSTI_03922	2.069e-13	82.0	COG1470@1|root,COG1470@2|Bacteria,1Q21G@1224|Proteobacteria,437PA@68525|delta/epsilon subdivisions,2X2XJ@28221|Deltaproteobacteria,2YX5A@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_112289_30	5888.CAK58395	2.779e-05	55.0	COG1404@1|root,KOG3525@2759|Eukaryota	5888.CAK58395|-	O	serine-type endopeptidase activity	-	-	-	ko:K08654	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	-
CMS3_k127_112289_9	1183438.GKIL_2549	6.707e-102	341.0	COG2957@1|root,COG2957@2|Bacteria,1G1FA@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CMS3_k127_112289_7	251221.35212247	5.931e-124	418.0	COG0388@1|root,COG0388@2|Bacteria,1G3B6@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM N-carbamoylputrescine amidase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_112289_8	1123355.JHYO01000002_gene1392	3.815e-112	367.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,36XEH@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_112289_17	502025.Hoch_0331	6.832e-66	230.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS3_k127_112289_23	391625.PPSIR1_30474	9.178e-39	159.0	COG0745@1|root,COG0745@2|Bacteria	391625.PPSIR1_30474|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_112289_2	502025.Hoch_5486	1.094e-194	612.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NXQ@68525|delta/epsilon subdivisions,2WJ9T@28221|Deltaproteobacteria,2Z34K@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_112289_25	391625.PPSIR1_31793	1.037e-21	108.0	COG1994@1|root,COG1994@2|Bacteria,1Q2IJ@1224|Proteobacteria,433TS@68525|delta/epsilon subdivisions,2X3F7@28221|Deltaproteobacteria,2YVTY@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_112289_5	502025.Hoch_1821	1.155e-165	572.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2YWNV@29|Myxococcales	28221|Deltaproteobacteria	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
CMS3_k127_112289_6	1144275.COCOR_00912	1.059e-149	486.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,42PFX@68525|delta/epsilon subdivisions,2WJS3@28221|Deltaproteobacteria,2YXB6@29|Myxococcales	28221|Deltaproteobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
CMS3_k127_112289_31	243231.GSU0877	0.0008571	51.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
CMS3_k127_112289_29	9371.XP_004713788.1	7.172e-06	58.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTVB@33213|Bilateria,4845F@7711|Chordata,48YFJ@7742|Vertebrata,3JEBN@40674|Mammalia,35281@311790|Afrotheria	33208|Metazoa	T	lipoprotein receptor-related protein	LRP5	GO:0000902,GO:0001501,GO:0001503,GO:0001568,GO:0001649,GO:0001654,GO:0001667,GO:0001702,GO:0001745,GO:0001763,GO:0001932,GO:0001933,GO:0001944,GO:0002009,GO:0002053,GO:0002076,GO:0002165,GO:0002376,GO:0002520,GO:0002791,GO:0003002,GO:0003008,GO:0003013,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006355,GO:0006357,GO:0006469,GO:0006629,GO:0006915,GO:0006928,GO:0007088,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007346,GO:0007350,GO:0007365,GO:0007367,GO:0007369,GO:0007389,GO:0007399,GO:0007423,GO:0007444,GO:0007447,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008015,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008217,GO:0008219,GO:0008284,GO:0008587,GO:0009056,GO:0009653,GO:0009790,GO:0009791,GO:0009798,GO:0009826,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009952,GO:0009953,GO:0009966,GO:0009987,GO:0010464,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010817,GO:0010941,GO:0012501,GO:0015026,GO:0016020,GO:0016043,GO:0016049,GO:0016052,GO:0016055,GO:0016125,GO:0016477,GO:0017147,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019320,GO:0019827,GO:0022612,GO:0023051,GO:0023052,GO:0030111,GO:0030154,GO:0030278,GO:0030279,GO:0030326,GO:0030879,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032991,GO:0033043,GO:0033673,GO:0033688,GO:0033690,GO:0034103,GO:0035019,GO:0035107,GO:0035108,GO:0035113,GO:0035114,GO:0035120,GO:0035218,GO:0035220,GO:0035223,GO:0035239,GO:0035282,GO:0035295,GO:0035426,GO:0038023,GO:0040007,GO:0040011,GO:0042074,GO:0042127,GO:0042325,GO:0042326,GO:0042592,GO:0042632,GO:0042733,GO:0042813,GO:0042981,GO:0043010,GO:0043067,GO:0043086,GO:0043235,GO:0043549,GO:0044092,GO:0044093,GO:0044238,GO:0044281,GO:0044282,GO:0044332,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045600,GO:0045667,GO:0045668,GO:0045669,GO:0045778,GO:0045787,GO:0045840,GO:0045859,GO:0045893,GO:0045931,GO:0045935,GO:0045936,GO:0045944,GO:0046365,GO:0046849,GO:0046850,GO:0046883,GO:0048070,GO:0048073,GO:0048076,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048539,GO:0048563,GO:0048569,GO:0048583,GO:0048589,GO:0048592,GO:0048593,GO:0048598,GO:0048705,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048754,GO:0048771,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050708,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050796,GO:0050877,GO:0050890,GO:0050896,GO:0051046,GO:0051049,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051338,GO:0051348,GO:0051674,GO:0051716,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0055088,GO:0055092,GO:0060033,GO:0060041,GO:0060042,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060341,GO:0060348,GO:0060349,GO:0060429,GO:0060443,GO:0060444,GO:0060560,GO:0060561,GO:0060562,GO:0060603,GO:0060612,GO:0060764,GO:0060828,GO:0061138,GO:0061178,GO:0061180,GO:0061298,GO:0061299,GO:0061304,GO:0061448,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071936,GO:0071944,GO:0072358,GO:0072359,GO:0080090,GO:0090068,GO:0090087,GO:0090254,GO:0090276,GO:0090596,GO:0098727,GO:0098796,GO:0098797,GO:0198738,GO:1901360,GO:1901575,GO:1901615,GO:1902262,GO:1902652,GO:1902680,GO:1902742,GO:1903506,GO:1903508,GO:1903530,GO:1904928,GO:1905114,GO:1990851,GO:1990909,GO:2000112,GO:2001141	-	ko:K03068	ko04150,ko04310,ko05200,ko05224,ko05225,ko05226,map04150,map04310,map05200,map05224,map05225,map05226	-	-	-	ko00000,ko00001,ko04131	-	-	-	FXa_inhibition,Ldl_recept_a,Ldl_recept_b
CMS3_k127_112289_21	1297742.A176_02414	2.747e-43	182.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pknB	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_112289_14	1297742.A176_00512	1.149e-82	296.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_1123251_8	96561.Dole_1674	8.434e-89	303.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2MHZH@213118|Desulfobacterales	28221|Deltaproteobacteria	L	TIGRFAM tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_1123251_13	502025.Hoch_5642	3.519e-63	224.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_1123251_9	502025.Hoch_5641	2.02e-85	303.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2YV06@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS3_k127_1123251_10	502025.Hoch_5640	2.352e-69	257.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,2Z010@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS3_k127_1123251_5	502025.Hoch_5639	5.99e-102	355.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2YUXM@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_1123251_12	1192034.CAP_0870	1.747e-63	238.0	COG4935@1|root,COG5492@1|root,COG4935@2|Bacteria,COG5492@2|Bacteria,1R2U6@1224|Proteobacteria	2|Bacteria	O	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF4215,LRR_5,P_proprotein
CMS3_k127_1123251_7	502025.Hoch_3341	6.204e-98	324.0	COG4577@1|root,COG4577@2|Bacteria,1QG1Y@1224|Proteobacteria,42SEX@68525|delta/epsilon subdivisions,2WPTK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1123251_0	502025.Hoch_3342	4.281e-235	734.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria,2YUBA@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_1123251_11	1299327.I546_2763	1.682e-64	250.0	COG2079@1|root,COG2079@2|Bacteria,2HVDJ@201174|Actinobacteria	201174|Actinobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
CMS3_k127_1123251_2	502025.Hoch_3343	8.525e-195	646.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,42RID@68525|delta/epsilon subdivisions,2WN9N@28221|Deltaproteobacteria,2YUME@29|Myxococcales	28221|Deltaproteobacteria	S	Zn-dependent proteases and their inactivated homologs	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_1123251_14	502025.Hoch_4200	8.822e-58	221.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,42QY6@68525|delta/epsilon subdivisions,2WN05@28221|Deltaproteobacteria,2YV4R@29|Myxococcales	28221|Deltaproteobacteria	P	Inositol monophosphatase family	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS3_k127_1123251_6	502025.Hoch_4199	5.33e-101	336.0	COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,43ARP@68525|delta/epsilon subdivisions,2X65R@28221|Deltaproteobacteria,2Z39B@29|Myxococcales	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
CMS3_k127_1123251_3	502025.Hoch_2622	5.487e-180	571.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1123251_1	448385.sce1787	4.047e-219	712.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YWJZ@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS3_k127_1123251_4	502025.Hoch_2623	6.839e-141	459.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,42QYC@68525|delta/epsilon subdivisions,2WN66@28221|Deltaproteobacteria,2Z2W4@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Kce	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
CMS3_k127_1123251_15	1254432.SCE1572_11090	9.322e-32	130.0	COG1846@1|root,COG1846@2|Bacteria,1N244@1224|Proteobacteria,42TYY@68525|delta/epsilon subdivisions,2WQP5@28221|Deltaproteobacteria,2YW5J@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS3_k127_113037_0	502025.Hoch_0548	8.499e-315	972.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42NDG@68525|delta/epsilon subdivisions,2WKYU@28221|Deltaproteobacteria,2YTWT@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_113037_1	373994.Riv7116_4103	1.223e-52	208.0	COG1073@1|root,COG1073@2|Bacteria,1GBEW@1117|Cyanobacteria	1117|Cyanobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_113037_2	391625.PPSIR1_19974	6.633e-23	115.0	COG3070@1|root,COG3070@2|Bacteria,1QEQQ@1224|Proteobacteria,4318J@68525|delta/epsilon subdivisions,2WWGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS3_k127_1145015_44	7176.CPIJ016596-PA	2.572e-13	78.0	2CY4I@1|root,2S1ZX@2759|Eukaryota,3A4ME@33154|Opisthokonta,3BS4H@33208|Metazoa,3D949@33213|Bilateria,42AYK@6656|Arthropoda,3T0CF@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1145015_35	502025.Hoch_2694	2.323e-29	126.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,42SW5@68525|delta/epsilon subdivisions,2WW97@28221|Deltaproteobacteria,2Z1TM@29|Myxococcales	28221|Deltaproteobacteria	S	Acyl-ACP thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
CMS3_k127_1145015_47	502025.Hoch_6783	4.586e-08	59.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	frzZ	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_1145015_26	502025.Hoch_0884	1.63e-67	252.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
CMS3_k127_1145015_31	1173027.Mic7113_2681	3.148e-54	197.0	COG0500@1|root,COG2226@2|Bacteria,1G0W5@1117|Cyanobacteria,1H8EK@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_1145015_10	1156844.KB891852_gene3794	1.029e-125	437.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
CMS3_k127_1145015_14	1121438.JNJA01000020_gene2747	2.198e-110	387.0	COG2114@1|root,COG2114@2|Bacteria,1RBTC@1224|Proteobacteria,42Y97@68525|delta/epsilon subdivisions,2WTJS@28221|Deltaproteobacteria,2MAZV@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,dCache_1
CMS3_k127_1145015_38	502025.Hoch_2727	5.993e-22	112.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS3_k127_1145015_46	883169.HMPREF9719_00599	5.566e-11	71.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,22M30@1653|Corynebacteriaceae	201174|Actinobacteria	Q	SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_1145015_34	572479.Hprae_0490	6.439e-43	163.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WAPY@53433|Halanaerobiales	186801|Clostridia	S	TIGRFAM DJ-1 family protein	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS3_k127_1145015_22	404589.Anae109_0474	7.057e-87	302.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,43A9Z@68525|delta/epsilon subdivisions,2X37W@28221|Deltaproteobacteria,2YV2G@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
CMS3_k127_1145015_33	290397.Adeh_1144	3.379e-53	196.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WQ51@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS3_k127_1145015_17	502025.Hoch_6388	6.223e-104	349.0	COG0515@1|root,COG0515@2|Bacteria,1PEGQ@1224|Proteobacteria,434JQ@68525|delta/epsilon subdivisions,2WYWY@28221|Deltaproteobacteria,2Z0U3@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1145015_23	1192034.CAP_8031	2.436e-78	271.0	COG0667@1|root,COG0667@2|Bacteria,1NWQE@1224|Proteobacteria,42ZW2@68525|delta/epsilon subdivisions,2WVDI@28221|Deltaproteobacteria,2YVXI@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2
CMS3_k127_1145015_9	314345.SPV1_07796	2.866e-154	513.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria	1224|Proteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_1145015_42	1210884.HG799465_gene12178	7.805e-18	91.0	COG1595@1|root,COG1595@2|Bacteria,2J0XE@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1145015_11	1123508.JH636440_gene2910	4.065e-125	453.0	COG2304@1|root,COG3712@1|root,COG2304@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,Peptidase_M64,VWA
CMS3_k127_1145015_0	502025.Hoch_3171	7.14e-289	925.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2YUGZ@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
CMS3_k127_1145015_16	1133849.O3I_007265	3.857e-105	365.0	COG0388@1|root,COG0388@2|Bacteria,2H03Y@201174|Actinobacteria,4G2QK@85025|Nocardiaceae	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_1145015_48	1089547.KB913013_gene2246	3.838e-06	60.0	COG3748@1|root,COG3748@2|Bacteria,4PN1Z@976|Bacteroidetes,47YB5@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CMS3_k127_1145015_12	1192034.CAP_0212	3.926e-122	413.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria,2Z3J1@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_1145015_43	215803.DB30_4126	5.75e-15	88.0	28PTA@1|root,2ZCEK@2|Bacteria,1RCNT@1224|Proteobacteria	215803.DB30_4126|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1145015_5	1392498.JQLH01000001_gene1357	1.631e-169	583.0	COG1361@1|root,COG2373@1|root,COG2885@1|root,COG2911@1|root,COG4932@1|root,COG5384@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2885@2|Bacteria,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5384@2|Bacteria,4NS01@976|Bacteroidetes,1I3QG@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C
CMS3_k127_1145015_36	1396858.Q666_06665	1.31e-28	136.0	COG3391@1|root,COG3391@2|Bacteria,1QX6H@1224|Proteobacteria,1T3DD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_1145015_19	502025.Hoch_4901	4.503e-95	329.0	COG2885@1|root,COG2885@2|Bacteria,1NRFN@1224|Proteobacteria,43CZ4@68525|delta/epsilon subdivisions,2X87C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS3_k127_1145015_15	861299.J421_4546	1.16e-108	373.0	COG0578@1|root,COG0578@2|Bacteria,1ZT6P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS3_k127_1145015_1	502025.Hoch_3186	1.653e-283	881.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2YTWY@29|Myxococcales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS3_k127_1145015_18	502025.Hoch_3188	3.555e-97	323.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,42PUJ@68525|delta/epsilon subdivisions,2WM9G@28221|Deltaproteobacteria,2YXXM@29|Myxococcales	28221|Deltaproteobacteria	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS3_k127_1145015_41	234267.Acid_0825	7.137e-18	96.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1145015_27	880073.Calab_1818	3.54e-67	241.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS3_k127_1145015_30	880073.Calab_1817	1.319e-54	217.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS3_k127_1145015_40	525904.Tter_2777	4.007e-20	102.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria	2|Bacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_35,CBM_6,GSDH,Kelch_1,Kelch_6
CMS3_k127_1145015_4	1254432.SCE1572_45120	1.138e-170	570.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_1145015_8	502025.Hoch_2647	8.585e-157	506.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	2|Bacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_1145015_29	502025.Hoch_5101	7.529e-58	224.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
CMS3_k127_1145015_2	517418.Ctha_0148	3.088e-213	702.0	COG1770@1|root,COG1770@2|Bacteria,1FDQZ@1090|Chlorobi	1090|Chlorobi	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.21.26,3.4.21.83	ko:K01322,ko:K01354	ko04614,ko05142,ko05143,map04614,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_1145015_13	404589.Anae109_3957	1.154e-110	372.0	COG0312@1|root,COG0312@2|Bacteria,1RBJZ@1224|Proteobacteria,42YBE@68525|delta/epsilon subdivisions,2WUP7@28221|Deltaproteobacteria,2YZ4Y@29|Myxococcales	28221|Deltaproteobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_1145015_7	1242864.D187_006073	5.431e-169	545.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42Y66@68525|delta/epsilon subdivisions,2WU83@28221|Deltaproteobacteria,2YX71@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_1145015_25	404589.Anae109_2885	1.892e-74	254.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42RIQ@68525|delta/epsilon subdivisions,2WNC7@28221|Deltaproteobacteria,2YZX2@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS3_k127_1145015_3	1254432.SCE1572_51745	1.58e-191	641.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1145015_24	321332.CYB_2461	2.567e-77	278.0	COG1225@1|root,COG1225@2|Bacteria,1G0JC@1117|Cyanobacteria,1GZAU@1129|Synechococcus	1117|Cyanobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1145015_6	448385.sce4837	2.407e-169	559.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,2YTV9@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_1145015_32	502025.Hoch_0246	9.031e-54	204.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1145015_21	502025.Hoch_5677	2.913e-91	308.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2Z304@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS3_k127_1145015_20	502025.Hoch_5676	1.016e-93	317.0	COG1409@1|root,COG1409@2|Bacteria,1MXD6@1224|Proteobacteria,42WZF@68525|delta/epsilon subdivisions,2WTE8@28221|Deltaproteobacteria,2Z34X@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_1145015_28	247490.KSU1_D0375	6.191e-64	235.0	COG0160@1|root,COG0160@2|Bacteria,2IYBU@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS3_k127_1145015_45	224324.aq_1244	4.591e-13	81.0	COG0558@1|root,COG0558@2|Bacteria,2G3Z1@200783|Aquificae	200783|Aquificae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_1154264_6	502025.Hoch_1898	8.247e-56	200.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,42WB9@68525|delta/epsilon subdivisions,2WSSJ@28221|Deltaproteobacteria,2YVJB@29|Myxococcales	28221|Deltaproteobacteria	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
CMS3_k127_1154264_2	502025.Hoch_0413	1.849e-152	499.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Thioredoxin_4,VKOR
CMS3_k127_1154264_4	502025.Hoch_6470	1.163e-84	291.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,432T5@68525|delta/epsilon subdivisions,2WY30@28221|Deltaproteobacteria,2YVSJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1154264_3	502025.Hoch_6471	2.24e-86	293.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,42RTA@68525|delta/epsilon subdivisions,2WNCA@28221|Deltaproteobacteria,2YV29@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_1154264_7	1278073.MYSTI_07483	5.352e-16	89.0	2BPY0@1|root,32IRR@2|Bacteria,1Q1YS@1224|Proteobacteria,437KR@68525|delta/epsilon subdivisions,2X2UV@28221|Deltaproteobacteria,2YUI3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1154264_8	1122604.JONR01000034_gene418	3.291e-11	71.0	295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1154264_10	1379698.RBG1_1C00001G0125	4.114e-08	58.0	2EGJW@1|root,3110Q@2|Bacteria,2NS2A@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1154264_0	1379698.RBG1_1C00001G0122	2.802e-245	770.0	COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria	2|Bacteria	G	MutL protein	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
CMS3_k127_1154264_9	319225.Plut_1571	9.595e-10	64.0	2E3QA@1|root,32YN8@2|Bacteria,1FFJG@1090|Chlorobi	1090|Chlorobi	M	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CMS3_k127_1157043_13	1407650.BAUB01000005_gene1293	1.318e-13	72.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1GZV7@1129|Synechococcus	1117|Cyanobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_1157043_3	1232410.KI421412_gene169	1.122e-196	649.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,43SYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_1157043_4	643648.Slip_0676	1.746e-187	608.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,42KFN@68298|Syntrophomonadaceae	186801|Clostridia	G	PFAM glycosyl transferase family 35	glgP2	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS3_k127_1157043_0	502025.Hoch_4095	1.591e-271	875.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2WIM3@28221|Deltaproteobacteria,2Z34A@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS3_k127_1157043_1	309801.trd_1935	1.472e-243	777.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,27XI0@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
CMS3_k127_1157043_6	502025.Hoch_5800	2.206e-124	414.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2YU1M@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
CMS3_k127_1157043_7	1054213.HMPREF9946_05279	6.353e-111	375.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2TT73@28211|Alphaproteobacteria,2JPZ4@204441|Rhodospirillales	204441|Rhodospirillales	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS3_k127_1157043_11	1395571.TMS3_0104165	1.681e-44	174.0	COG2207@1|root,COG2207@2|Bacteria,1RB13@1224|Proteobacteria,1S2ZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
CMS3_k127_1157043_2	1254432.SCE1572_04480	8.449e-197	632.0	COG1716@1|root,COG2203@1|root,COG3829@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_1157043_9	502025.Hoch_5107	1.539e-58	228.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_5107|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1157043_8	502025.Hoch_5105	2.731e-64	233.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WMT5@28221|Deltaproteobacteria,2YV92@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS3_k127_1157043_14	1297742.A176_02765	1.992e-13	77.0	COG1664@1|root,COG1664@2|Bacteria,1PY09@1224|Proteobacteria,434ZT@68525|delta/epsilon subdivisions,2WZAN@28221|Deltaproteobacteria,2Z1QG@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_1157043_5	502025.Hoch_4142	2.022e-164	529.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,42QDI@68525|delta/epsilon subdivisions,2WJMG@28221|Deltaproteobacteria,2YWDT@29|Myxococcales	28221|Deltaproteobacteria	H	glutamate--cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
CMS3_k127_1157043_10	237368.SCABRO_00780	2.51e-53	214.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_1157043_15	1192034.CAP_3816	0.0003162	49.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K10926,ko:K12285	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin_GH
CMS3_k127_1173656_0	1120950.KB892746_gene3575	3.854e-298	938.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4DTE4@85009|Propionibacteriales	201174|Actinobacteria	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_1173656_1	765912.Thimo_1436	2.36e-266	859.0	COG0236@1|root,COG1028@1|root,COG2070@1|root,COG3321@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria,1WXNA@135613|Chromatiales	135613|Chromatiales	IQ	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,ketoacyl-synt
CMS3_k127_1183760_2	502025.Hoch_6863	9.598e-74	257.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2YVS1@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
CMS3_k127_1183760_0	502025.Hoch_6862	2.361e-243	762.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2YWA3@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
CMS3_k127_1183760_3	502025.Hoch_6861	2.644e-35	155.0	COG0526@1|root,COG0526@2|Bacteria,1PEIY@1224|Proteobacteria,43DSH@68525|delta/epsilon subdivisions,2X9Y8@28221|Deltaproteobacteria,2Z01B@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1183760_1	502025.Hoch_5266	5.537e-135	437.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WKFE@28221|Deltaproteobacteria,2YUTV@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
CMS3_k127_1183760_4	1304885.AUEY01000003_gene458	2.854e-11	73.0	2971T@1|root,2ZUA7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1183760_5	909663.KI867150_gene1009	2.403e-08	55.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2WJ7P@28221|Deltaproteobacteria,2MRDA@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Aminopeptidase I zinc metalloprotease (M18)	apeA	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
CMS3_k127_1191700_0	1297742.A176_05581	1.713e-250	784.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_1191947_1	1345695.CLSA_c17400	5.761e-09	66.0	COG4886@1|root,COG5263@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5263@2|Bacteria,COG5492@2|Bacteria,1UZZJ@1239|Firmicutes,25EQC@186801|Clostridia,36URC@31979|Clostridiaceae	186801|Clostridia	N	cell wall binding	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_4,LRR_8
CMS3_k127_1191947_0	391625.PPSIR1_05098	1.531e-38	158.0	COG0615@1|root,COG0615@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_121638_2	1470593.BW43_05486	1.216e-09	69.0	COG3921@1|root,COG3921@2|Bacteria,1N3WR@1224|Proteobacteria,1RSB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	extensin	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
CMS3_k127_121638_1	1340493.JNIF01000003_gene4405	1.101e-92	312.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_121638_0	1183438.GKIL_4354	4.018e-161	538.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_1229316_5	443143.GM18_3946	1.216e-36	156.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,43W1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1229316_3	1379698.RBG1_1C00001G0856	3.838e-81	280.0	COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
CMS3_k127_1229316_0	1379698.RBG1_1C00001G0857	8.37e-165	540.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1229316_8	1192034.CAP_1506	2.223e-18	93.0	297PQ@1|root,2ZUWM@2|Bacteria,1PYGM@1224|Proteobacteria,435C6@68525|delta/epsilon subdivisions,2WZPR@28221|Deltaproteobacteria,2Z2HB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1229316_9	1192034.CAP_1507	5.709e-17	85.0	2DGCA@1|root,2ZVDU@2|Bacteria,1PCAI@1224|Proteobacteria,43E4G@68525|delta/epsilon subdivisions,2WZPI@28221|Deltaproteobacteria,2Z2H4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1229316_7	237368.SCABRO_00535	8.236e-25	119.0	COG3637@1|root,COG3637@2|Bacteria,2J46X@203682|Planctomycetes	203682|Planctomycetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1229316_6	1192034.CAP_1503	9.993e-31	129.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,434YV@68525|delta/epsilon subdivisions,2WZ9S@28221|Deltaproteobacteria,2Z1NI@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1229316_1	1192034.CAP_1505	7.645e-138	462.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2Z380@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	5TM-5TMR_LYT,Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2
CMS3_k127_1229316_2	880073.Calab_1263	5.442e-122	415.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_1229316_4	243231.GSU3225	1.062e-49	192.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,43AJ0@68525|delta/epsilon subdivisions,2X5Z8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1246399_0	648996.Theam_0543	4.16e-35	151.0	COG2067@1|root,COG2067@2|Bacteria,2G47R@200783|Aquificae	200783|Aquificae	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_1253559_1	502025.Hoch_3547	7.102e-103	347.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS3_k127_1253559_0	502025.Hoch_3546	1.409e-145	479.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2Z0ZJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1253559_2	1149133.ppKF707_0665	4.703e-76	262.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,1YD8J@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1268438_3	502025.Hoch_4074	1.652e-58	210.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1268438_2	1502851.FG93_03224	9.761e-64	227.0	COG1024@1|root,COG1024@2|Bacteria,1NQM5@1224|Proteobacteria,2TSP1@28211|Alphaproteobacteria,3JUF6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_16935	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_1268438_0	269799.Gmet_2209	2.424e-119	405.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	-	-	-	-	-	-	-	-	-	-	MM_CoA_mutase
CMS3_k127_1268438_8	292459.STH2465	3.145e-25	123.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia	186801|Clostridia	I	TIGRFAM Methylmalonyl-CoA mutase, C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CMS3_k127_1268438_9	1174684.EBMC1_15297	1.385e-14	85.0	COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,2U7S8@28211|Alphaproteobacteria,2K15C@204457|Sphingomonadales	204457|Sphingomonadales	O	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1268438_11	1303518.CCALI_02610	7.903e-07	63.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66,3.4.24.40	ko:K01406,ko:K08651,ko:K11904	ko01503,ko03070,map01503,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko02044,ko03110	3.A.23.1	-	-	Astacin,CARDB,He_PIG,PKD,Peptidase_M10,Peptidase_S8
CMS3_k127_1268438_4	608538.HTH_1208	7.117e-34	153.0	COG1404@1|root,COG1404@2|Bacteria,2G4GX@200783|Aquificae	200783|Aquificae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_1268438_10	1172180.KB911789_gene2879	1.996e-07	65.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M6, immune inhibitor A	ina	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
CMS3_k127_1268438_7	502025.Hoch_5446	9.139e-28	119.0	COG1366@1|root,COG1366@2|Bacteria,1NG3I@1224|Proteobacteria,42W69@68525|delta/epsilon subdivisions,2WS39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1268438_1	595460.RRSWK_02465	2.545e-64	233.0	COG1181@1|root,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_1268438_5	502025.Hoch_5230	5.746e-32	132.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	Peptidase_C39,Peptidase_C70
CMS3_k127_1268438_6	1192034.CAP_5278	8.382e-31	128.0	COG1357@1|root,COG1357@2|Bacteria,1RJ94@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1282837_5	1128421.JAGA01000002_gene308	2.79e-11	77.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1282837_1	526225.Gobs_4702	1.377e-36	152.0	COG2232@1|root,COG2232@2|Bacteria,2I3GF@201174|Actinobacteria,4ESX6@85013|Frankiales	201174|Actinobacteria	S	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,ATPgrasp_Ter
CMS3_k127_1282837_0	1519464.HY22_10225	3.803e-111	376.0	COG0673@1|root,COG0673@2|Bacteria,1FEZX@1090|Chlorobi	1090|Chlorobi	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_1282837_2	1266925.JHVX01000005_gene1962	4.301e-25	121.0	COG2227@1|root,COG2227@2|Bacteria,1RHSX@1224|Proteobacteria,2W9ZG@28216|Betaproteobacteria,373RP@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_1282837_3	243231.GSU0623	3.352e-22	109.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,43U7K@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
CMS3_k127_1282837_4	1123392.AQWL01000003_gene190	1.629e-19	97.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2VUZW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
CMS3_k127_1284609_14	502025.Hoch_3167	6.667e-57	201.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
CMS3_k127_1284609_5	1192034.CAP_0190	2.347e-121	420.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 31 family	yihQ	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929	3.2.1.177,3.2.1.199	ko:K01811,ko:K15922	-	-	R00802,R11543	RC00028,RC00059,RC00077,RC00451	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
CMS3_k127_1284609_15	1192034.CAP_8613	3.08e-55	207.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_1284609_12	502025.Hoch_4630	8.158e-74	254.0	2AMW0@1|root,31CSU@2|Bacteria,1Q9ME@1224|Proteobacteria,434GQ@68525|delta/epsilon subdivisions,2WYU2@28221|Deltaproteobacteria,2Z0M8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1284609_20	290397.Adeh_1634	6.005e-05	57.0	COG1520@1|root,COG1520@2|Bacteria,1Q3BK@1224|Proteobacteria,4392T@68525|delta/epsilon subdivisions,2X48J@28221|Deltaproteobacteria,2YYHQ@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_1284609_2	502025.Hoch_4631	2.922e-199	628.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria,2YWY0@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1284609_11	391625.PPSIR1_17070	1.796e-78	274.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_1284609_1	448385.sce9161	1.598e-222	732.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1284609_19	378806.STAUR_7433	2.122e-15	89.0	COG1361@1|root,COG3055@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1284609_8	1192034.CAP_2423	7.43e-95	342.0	COG3903@1|root,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
CMS3_k127_1284609_17	1144275.COCOR_06523	4.702e-35	147.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42VZ4@68525|delta/epsilon subdivisions,2WRDI@28221|Deltaproteobacteria,2YW4T@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_1284609_7	1254432.SCE1572_25215	2.896e-104	357.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,437GM@68525|delta/epsilon subdivisions,2X2PE@28221|Deltaproteobacteria,2YUSG@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1284609_13	502025.Hoch_4959	1.805e-60	233.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4399Y@68525|delta/epsilon subdivisions,2X4HE@28221|Deltaproteobacteria,2YZ0V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase; unclassified specificity.	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1284609_9	502025.Hoch_1394	2.828e-93	326.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,437GM@68525|delta/epsilon subdivisions,2X2PE@28221|Deltaproteobacteria,2YUSG@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1284609_6	1278073.MYSTI_00918	6.16e-113	386.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,4380T@68525|delta/epsilon subdivisions,2X3AT@28221|Deltaproteobacteria,2YZH7@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_1284609_18	96561.Dole_3074	1.344e-23	113.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_1284609_0	886293.Sinac_1156	1.005e-241	792.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1284609_4	502025.Hoch_5062	4.132e-174	556.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria,2YYYY@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1284609_3	886293.Sinac_1156	1.878e-191	639.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1309393_0	502025.Hoch_2720	7.7e-61	235.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria	1224|Proteobacteria	C	12 heme-binding sites	cbcC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_1309393_1	575540.Isop_2807	8.81e-10	72.0	COG5276@1|root,COG5276@2|Bacteria,2IXW8@203682|Planctomycetes	203682|Planctomycetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS3_k127_1317448_7	1220534.B655_1862	0.0001677	48.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_1317448_4	1188256.BASI01000003_gene2827	3.485e-07	62.0	COG0392@1|root,COG0392@2|Bacteria,1R4IS@1224|Proteobacteria,2U40H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS3_k127_1317448_2	1254432.SCE1572_52120	3.572e-27	119.0	COG1309@1|root,COG1309@2|Bacteria,1NHKU@1224|Proteobacteria,42XA9@68525|delta/epsilon subdivisions,2WTFR@28221|Deltaproteobacteria,2Z0WM@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1317448_0	1229780.BN381_50061	2.057e-89	319.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,3UWHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_1317448_3	926550.CLDAP_26360	5.807e-12	78.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1317448_1	1144275.COCOR_07886	1.92e-42	175.0	COG1633@1|root,COG1633@2|Bacteria,1P131@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1317448_6	56107.Cylst_1402	6.572e-05	54.0	COG2227@1|root,COG2227@2|Bacteria,1GCG8@1117|Cyanobacteria,1HQ16@1161|Nostocales	1117|Cyanobacteria	H	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_21
CMS3_k127_1331486_46	502025.Hoch_4943	1.341e-08	66.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tonB1	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_1331486_2	502025.Hoch_0068	1.431e-257	826.0	COG3227@1|root,COG3227@2|Bacteria,1Q6DC@1224|Proteobacteria,432XR@68525|delta/epsilon subdivisions,2WYJ7@28221|Deltaproteobacteria,2Z34H@29|Myxococcales	28221|Deltaproteobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1331486_34	448385.sce0201	4.147e-26	125.0	COG5640@1|root,COG5640@2|Bacteria,1Q1VE@1224|Proteobacteria,432CB@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_1331486_17	1111479.AXAR01000005_gene522	2.313e-87	304.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,2799D@186823|Alicyclobacillaceae	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
CMS3_k127_1331486_7	1206720.BAFQ01000164_gene4301	1.319e-154	504.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FUZV@85025|Nocardiaceae	201174|Actinobacteria	IQ	synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_1331486_11	83406.HDN1F_16010	3.509e-113	402.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1S1M2@1236|Gammaproteobacteria,1J5J5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1331486_22	443143.GM18_2582	7.093e-61	234.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42PHT@68525|delta/epsilon subdivisions,2WKTH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS3_k127_1331486_26	298655.KI912266_gene2278	1.396e-53	204.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4EWFM@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1331486_33	502025.Hoch_3461	9.634e-29	128.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_1331486_25	448385.sce9149	6.437e-56	212.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce9149|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1331486_41	246969.TAM4_499	5.415e-14	86.0	COG0515@1|root,arCOG00372@1|root,arCOG03264@1|root,arCOG00372@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2XWYZ@28890|Euryarchaeota,2437Z@183968|Thermococci	183968|Thermococci	T	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1331486_51	504472.Slin_4320	0.0001521	55.0	COG1621@1|root,COG1621@2|Bacteria,4NG8H@976|Bacteroidetes,47NKE@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS3_k127_1331486_9	880073.Calab_2583	9.381e-144	484.0	COG2230@1|root,COG2230@2|Bacteria,2NQ94@2323|unclassified Bacteria	2|Bacteria	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS3_k127_1331486_27	713586.KB900536_gene2820	2.111e-50	194.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_1331486_8	502025.Hoch_5035	7.934e-148	481.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42PV5@68525|delta/epsilon subdivisions,2WIKH@28221|Deltaproteobacteria,2Z1EJ@29|Myxococcales	28221|Deltaproteobacteria	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS3_k127_1331486_24	1232410.KI421415_gene3122	1.71e-57	229.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CMS3_k127_1331486_13	502025.Hoch_5811	1.717e-99	362.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1331486_42	590998.Celf_0029	8.986e-13	83.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4F1P9@85016|Cellulomonadaceae	201174|Actinobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_1331486_35	1313172.YM304_13950	7.269e-21	105.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS3_k127_1331486_15	1192034.CAP_5944	1.255e-95	334.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,CBM_2,Glyco_hydro_48
CMS3_k127_1331486_3	502025.Hoch_2491	1.64e-252	820.0	COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUXH@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS3_k127_1331486_43	1089549.AZUQ01000001_gene2769	1.141e-11	78.0	COG3227@1|root,COG5640@1|root,COG3227@2|Bacteria,COG5640@2|Bacteria,2IAP0@201174|Actinobacteria,4EZXV@85014|Glycomycetales	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_1331486_31	1403819.BATR01000162_gene5397	1.3e-40	172.0	COG0584@1|root,COG0584@2|Bacteria,46T8X@74201|Verrucomicrobia,2IVQ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
CMS3_k127_1331486_10	1121468.AUBR01000028_gene1508	4.396e-143	469.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,42HQG@68295|Thermoanaerobacterales	186801|Clostridia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
CMS3_k127_1331486_52	1166018.FAES_5055	0.0003533	51.0	COG4773@1|root,COG4773@2|Bacteria,4NF92@976|Bacteroidetes,47MSH@768503|Cytophagia	976|Bacteroidetes	P	TIGRFAM TonB-dependent siderophore receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS3_k127_1331486_48	1500259.JQLD01000001_gene4444	2.699e-05	54.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria,4BFEI@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1331486_16	1227454.C446_14734	9.982e-92	316.0	COG0665@1|root,arCOG00755@2157|Archaea,2XUM9@28890|Euryarchaeota,23S19@183963|Halobacteria	183963|Halobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	solA	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_1331486_20	502025.Hoch_6643	5.907e-68	256.0	COG1595@1|root,COG1595@2|Bacteria,1RKMN@1224|Proteobacteria,431Z5@68525|delta/epsilon subdivisions,2WWH8@28221|Deltaproteobacteria,2Z13Y@29|Myxococcales	28221|Deltaproteobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1331486_6	404589.Anae109_0189	6.798e-188	638.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
CMS3_k127_1331486_23	502025.Hoch_3796	6.823e-60	211.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2WNNI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SEC-C motif domain protein	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
CMS3_k127_1331486_14	502025.Hoch_3886	6.403e-97	327.0	COG0278@1|root,COG0316@1|root,COG0607@1|root,COG0278@2|Bacteria,COG0316@2|Bacteria,COG0607@2|Bacteria,1MZ4V@1224|Proteobacteria,43154@68525|delta/epsilon subdivisions,2WWCI@28221|Deltaproteobacteria,2YVCT@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin,Rhodanese
CMS3_k127_1331486_36	929703.KE386491_gene4134	1.365e-20	106.0	COG0823@1|root,COG5384@1|root,COG0823@2|Bacteria,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes	976|Bacteroidetes	J	InterPro IPR003367	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,TSP_3
CMS3_k127_1331486_4	1144275.COCOR_03202	4.529e-193	624.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YTUY@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_1331486_44	1192034.CAP_5082	6.831e-11	76.0	COG3055@1|root,COG5184@1|root,COG3055@2|Bacteria,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2Z3A7@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_1331486_19	1313421.JHBV01000016_gene5608	2.495e-74	278.0	COG0457@1|root,COG0457@2|Bacteria,4NND8@976|Bacteroidetes	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_1331486_1	502025.Hoch_6833	3.037e-277	867.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YX5W@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_1331486_37	502025.Hoch_6704	2.396e-16	85.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_6704|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1331486_49	866536.Belba_0844	4.403e-05	56.0	COG0729@1|root,COG0729@2|Bacteria,4NMUN@976|Bacteroidetes,47Y2C@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_1331486_29	404589.Anae109_3838	1.015e-43	174.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,43AFC@68525|delta/epsilon subdivisions,2X64J@28221|Deltaproteobacteria,2Z0UN@29|Myxococcales	28221|Deltaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_1331486_0	502025.Hoch_0404	1.121e-280	880.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,42PQK@68525|delta/epsilon subdivisions,2WJCT@28221|Deltaproteobacteria,2YUHK@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1331486_5	862908.BMS_1303	7.81e-193	632.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,1MXNJ@1224|Proteobacteria,42Q9Q@68525|delta/epsilon subdivisions,2WKCR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,PTS_EIIA_2
CMS3_k127_1331486_39	396588.Tgr7_0724	1.936e-14	88.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,1S668@1236|Gammaproteobacteria,1WYAA@135613|Chromatiales	135613|Chromatiales	G	PTS IIA-like nitrogen-regulatory protein PtsN	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS3_k127_1331486_40	1254432.SCE1572_43820	2.159e-14	81.0	2BK2A@1|root,32EFM@2|Bacteria,1Q07X@1224|Proteobacteria,435HR@68525|delta/epsilon subdivisions,2WZVF@28221|Deltaproteobacteria,2Z2U0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1331486_12	448385.sce7575	2.547e-109	371.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria,2YXMU@29|Myxococcales	28221|Deltaproteobacteria	I	Long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_1331486_28	880073.Calab_1728	2.467e-48	186.0	COG2374@1|root,COG2374@2|Bacteria,2NRBP@2323|unclassified Bacteria	2|Bacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_1331486_18	1116472.MGMO_157c00050	3.261e-80	276.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1S2Y7@1236|Gammaproteobacteria,1XG6U@135618|Methylococcales	135618|Methylococcales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1331486_50	1123274.KB899431_gene3241	0.0001065	48.0	2AU0F@1|root,31JKB@2|Bacteria	2|Bacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1331486_32	936155.HFELIS_16070	1.108e-31	124.0	2AICC@1|root,318TJ@2|Bacteria,1Q0XM@1224|Proteobacteria,431XH@68525|delta/epsilon subdivisions,2YSDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1338517_2	1304872.JAGC01000003_gene2864	9.445e-75	260.0	COG3866@1|root,COG3866@2|Bacteria,1RFAV@1224|Proteobacteria	1224|Proteobacteria	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_1338517_1	1144275.COCOR_03484	2.246e-92	331.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,PEGA,Pkinase
CMS3_k127_1338517_3	502025.Hoch_5322	1.3e-70	266.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TPR_12
CMS3_k127_1338517_0	886293.Sinac_1156	2.486e-194	642.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_134302_0	1289387.AUKW01000004_gene1173	2.959e-44	168.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.196,3.2.1.68	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02111,R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS3_k127_134302_4	404589.Anae109_4396	3.464e-11	73.0	COG2267@1|root,COG2267@2|Bacteria,1PXRQ@1224|Proteobacteria,434SS@68525|delta/epsilon subdivisions,2X90B@28221|Deltaproteobacteria,2Z19P@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_134302_2	525904.Tter_0136	3.311e-21	105.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_134302_3	502025.Hoch_5753	1.804e-16	82.0	COG2378@1|root,COG2378@2|Bacteria,1QAGU@1224|Proteobacteria,434D3@68525|delta/epsilon subdivisions,2WYQ2@28221|Deltaproteobacteria,2Z0CG@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
CMS3_k127_1347046_0	1356852.N008_12450	9.602e-86	310.0	COG1033@1|root,COG1033@2|Bacteria,4NKTD@976|Bacteroidetes,47UF5@768503|Cytophagia	976|Bacteroidetes	S	Patched family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_1347046_3	525897.Dbac_2226	4.947e-12	79.0	COG3103@1|root,COG3103@2|Bacteria,1R0RN@1224|Proteobacteria,43EF8@68525|delta/epsilon subdivisions,2X88A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1347046_2	879212.DespoDRAFT_01908	6.645e-31	141.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria,2MKUD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_1347046_1	1223523.H340_30293	1.49e-40	165.0	COG3320@1|root,COG3320@2|Bacteria,2IINT@201174|Actinobacteria	201174|Actinobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
CMS3_k127_1349577_7	502025.Hoch_2512	1.461e-38	156.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1349577_0	502025.Hoch_4905	1.819e-217	701.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_4905|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1349577_2	502025.Hoch_4906	3.868e-123	414.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_4906|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1349577_1	502025.Hoch_2591	5.333e-134	436.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	3.1.4.4	ko:K01115	ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000,ko04131	-	-	-	PLDc,PLDc_2
CMS3_k127_1349577_4	502025.Hoch_0245	1.793e-74	268.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325	CDP-OH_P_transf
CMS3_k127_1349577_8	497964.CfE428DRAFT_2568	1.586e-33	142.0	COG2220@1|root,COG2220@2|Bacteria,46UIR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_1349577_5	502025.Hoch_5675	2.76e-52	198.0	COG1279@1|root,COG1279@2|Bacteria	2|Bacteria	S	arginine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS3_k127_1349577_6	1087481.AGFX01000037_gene4354	3.648e-44	169.0	COG5470@1|root,COG5470@2|Bacteria,1VSV2@1239|Firmicutes,4HUUN@91061|Bacilli,26X9M@186822|Paenibacillaceae	91061|Bacilli	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1349577_9	1163617.SCD_n00827	3.104e-24	118.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS3_k127_1349577_3	502025.Hoch_6741	2.472e-76	261.0	2ABYR@1|root,311G5@2|Bacteria,1RD0Z@1224|Proteobacteria,42S20@68525|delta/epsilon subdivisions,2WNAC@28221|Deltaproteobacteria,2YW4B@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1349577_10	502025.Hoch_0362	9.142e-10	63.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,4389R@68525|delta/epsilon subdivisions,2XA3N@28221|Deltaproteobacteria,2YWAI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_1368080_14	448385.sce7555	2.469e-06	59.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria,2YU2Y@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
CMS3_k127_1368080_12	404589.Anae109_3527	1.123e-25	120.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS3_k127_1368080_1	886293.Sinac_1156	6.318e-281	906.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1368080_11	1122201.AUAZ01000001_gene2304	1.589e-45	188.0	COG3608@1|root,COG3608@2|Bacteria,1R784@1224|Proteobacteria,1RRY6@1236|Gammaproteobacteria,4661V@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
CMS3_k127_1368080_6	266117.Rxyl_3013	3.224e-95	317.0	COG1028@1|root,COG1028@2|Bacteria	266117.Rxyl_3013|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1368080_5	502025.Hoch_1692	7.554e-96	322.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria	1224|Proteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.310	ko:K16843	ko00270,map00270	-	R05693	RC00031	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_1368080_10	502025.Hoch_5881	1.181e-53	197.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,2Z0M1@29|Myxococcales	28221|Deltaproteobacteria	C	fumarate reductase) cytochrome b subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS3_k127_1368080_0	502025.Hoch_5880	0.0	1058.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,2Z30R@29|Myxococcales	28221|Deltaproteobacteria	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_1368080_4	502025.Hoch_5879	9.428e-109	381.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WK9D@28221|Deltaproteobacteria,2YXAV@29|Myxococcales	28221|Deltaproteobacteria	C	Fumarate reductase, iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2395	Fer2_3,Fer4_7,Fer4_8
CMS3_k127_1368080_9	1461694.ATO9_00105	3.06e-54	209.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2PDTE@252301|Oceanicola	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_1368080_2	1535287.JP74_03800	4.372e-172	548.0	COG1415@1|root,COG1415@2|Bacteria,1QQ3V@1224|Proteobacteria,2TRG5@28211|Alphaproteobacteria,3N7TI@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF763)	MA20_26605	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
CMS3_k127_1368080_13	869210.Marky_0373	2.245e-13	83.0	COG3895@1|root,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
CMS3_k127_1368080_7	483219.LILAB_23790	2.313e-64	238.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
CMS3_k127_1368080_3	502025.Hoch_0403	3.744e-158	516.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX5U@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
CMS3_k127_1368080_8	502025.Hoch_0402	9.856e-61	217.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX63@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
CMS3_k127_1375103_1	502025.Hoch_4280	1.576e-14	74.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat,TPR_12,Yop-YscD_cpl
CMS3_k127_1375103_0	502025.Hoch_4281	2.294e-130	432.0	COG1376@1|root,COG1376@2|Bacteria,1NKBB@1224|Proteobacteria,432T9@68525|delta/epsilon subdivisions,2WYN9@28221|Deltaproteobacteria,2YWNH@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS3_k127_1391_3	502025.Hoch_3551	6.874e-56	207.0	COG4856@1|root,COG4856@2|Bacteria	2|Bacteria	O	YbbR-like protein	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
CMS3_k127_1391_1	502025.Hoch_3550	2.768e-100	346.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2YV5I@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
CMS3_k127_1391_2	502025.Hoch_3549	3.486e-86	311.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YZJ4@29|Myxococcales	28221|Deltaproteobacteria	H	Pterin binding enzyme	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS3_k127_1391_0	502025.Hoch_3548	3.166e-207	650.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2YUHW@29|Myxococcales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS3_k127_1398836_0	396588.Tgr7_0551	2.068e-14	87.0	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1X1NS@135613|Chromatiales	135613|Chromatiales	U	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_1412874_2	502025.Hoch_6409	3.843e-84	298.0	COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,42Q18@68525|delta/epsilon subdivisions,2WMER@28221|Deltaproteobacteria,2Z26C@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_1412874_3	502025.Hoch_6351	8.372e-59	221.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2YVWN@29|Myxococcales	28221|Deltaproteobacteria	J	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
CMS3_k127_1412874_0	502025.Hoch_0177	1.153e-110	390.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMJ8@28221|Deltaproteobacteria,2Z2Y9@29|Myxococcales	28221|Deltaproteobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS3_k127_1412874_1	502025.Hoch_2467	5.871e-107	359.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2YUWE@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_1412874_4	502025.Hoch_2466	2.091e-41	153.0	2CDR8@1|root,32ZSF@2|Bacteria,1NCBG@1224|Proteobacteria,42V4S@68525|delta/epsilon subdivisions,2WSDP@28221|Deltaproteobacteria,2YVN6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1429625_20	926549.KI421517_gene3783	1.982e-08	61.0	COG2050@1|root,COG2050@2|Bacteria,4NT7R@976|Bacteroidetes,47RY0@768503|Cytophagia	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1429625_15	1458357.BG58_11705	7.514e-38	157.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,1K363@119060|Burkholderiaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1429625_8	1254432.SCE1572_50660	1.345e-99	342.0	2DBEW@1|root,2Z8UY@2|Bacteria,1QZEI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
CMS3_k127_1429625_19	1121930.AQXG01000002_gene1975	8.005e-09	67.0	28IZY@1|root,2Z8X8@2|Bacteria,4NKJG@976|Bacteroidetes,1IYGD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1429625_7	378806.STAUR_2012	1.451e-106	359.0	2DB7V@1|root,2Z7NX@2|Bacteria,1N9SI@1224|Proteobacteria,43ANT@68525|delta/epsilon subdivisions,2WTAF@28221|Deltaproteobacteria,2YYSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1429625_4	448385.sce9148	2.631e-111	368.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2YUHA@29|Myxococcales	28221|Deltaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1429625_11	331869.BAL199_25014	1.536e-47	174.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,4BQUU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_16590	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
CMS3_k127_1429625_6	502025.Hoch_5942	5.553e-108	353.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2YUHQ@29|Myxococcales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS3_k127_1429625_13	215803.DB30_6360	2.808e-41	158.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_1429625_0	391625.PPSIR1_21614	6.571e-164	538.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,42ZIG@68525|delta/epsilon subdivisions,2WUZE@28221|Deltaproteobacteria,2YX8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS3_k127_1429625_10	926550.CLDAP_11590	1.925e-54	200.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS3_k127_1429625_16	68170.KL590535_gene3742	1.003e-28	118.0	COG2920@1|root,COG2920@2|Bacteria,2IQB2@201174|Actinobacteria,4EBVV@85010|Pseudonocardiales	201174|Actinobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS3_k127_1429625_1	1121930.AQXG01000001_gene1117	1.193e-150	486.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,1IWTF@117747|Sphingobacteriia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_1429625_2	404589.Anae109_4112	1.879e-136	447.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
CMS3_k127_1429625_12	797209.ZOD2009_18045	5.145e-43	160.0	COG0251@1|root,arCOG01630@2157|Archaea,2XY4I@28890|Euryarchaeota,23X7B@183963|Halobacteria	183963|Halobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_1429625_14	1111479.AXAR01000003_gene1515	1.709e-40	156.0	COG1853@1|root,COG1853@2|Bacteria,1V5M1@1239|Firmicutes,4HJWQ@91061|Bacilli	91061|Bacilli	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
CMS3_k127_1429625_17	1379270.AUXF01000005_gene618	1.64e-28	129.0	COG4758@1|root,COG4758@2|Bacteria,1ZU48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1707)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
CMS3_k127_1429625_5	502025.Hoch_3492	2.6e-108	374.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_1429625_3	1232410.KI421412_gene166	1.817e-126	415.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1429625_9	269799.Gmet_2150	1.893e-68	241.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria,43UFV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_1429625_18	767817.Desgi_0476	4.952e-10	65.0	COG2159@1|root,COG2159@2|Bacteria,1W7C5@1239|Firmicutes,258X8@186801|Clostridia,265NS@186807|Peptococcaceae	186801|Clostridia	S	TIM-barrel fold metal-dependent hydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_1436908_10	1041522.MCOL_V204605	6.793e-78	269.0	COG1024@1|root,COG1024@2|Bacteria,2HEIS@201174|Actinobacteria,237CX@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_1436908_11	1254432.SCE1572_51270	4.312e-77	265.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,42T5R@68525|delta/epsilon subdivisions,2WX1F@28221|Deltaproteobacteria,2Z02S@29|Myxococcales	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS3_k127_1436908_13	640081.Dsui_0297	9.161e-65	228.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2W0B5@28216|Betaproteobacteria,2KXXD@206389|Rhodocyclales	206389|Rhodocyclales	S	Sugar fermentation stimulation protein	-	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
CMS3_k127_1436908_2	926569.ANT_05220	1.922e-190	620.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_1436908_14	1173028.ANKO01000129_gene1998	1.087e-63	233.0	COG1785@1|root,COG1785@2|Bacteria,1G4BJ@1117|Cyanobacteria	1117|Cyanobacteria	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS3_k127_1436908_15	1254432.SCE1572_47275	1.459e-63	227.0	COG2267@1|root,COG2267@2|Bacteria,1NYNM@1224|Proteobacteria,43CA0@68525|delta/epsilon subdivisions,2X7KG@28221|Deltaproteobacteria,2YVW6@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_1436908_19	118166.JH976537_gene1767	2.518e-45	186.0	COG4333@1|root,COG4333@2|Bacteria,1G73U@1117|Cyanobacteria,1HCQ3@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1643)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1643
CMS3_k127_1436908_16	1353529.M899_0925	1.707e-59	221.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,42UNJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_1436908_22	338969.Rfer_0415	2.839e-41	158.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,4AICZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Disulfide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
CMS3_k127_1436908_18	1254432.SCE1572_31010	2.228e-48	190.0	COG4402@1|root,COG4402@2|Bacteria,1QA5C@1224|Proteobacteria,434UU@68525|delta/epsilon subdivisions,2WZ5W@28221|Deltaproteobacteria,2Z1E4@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_1436908_27	502025.Hoch_3501	1.333e-09	68.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_1436908_0	502025.Hoch_6550	0.0	1666.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YUG7@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD/H associated	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS3_k127_1436908_1	886293.Sinac_1156	1.652e-227	755.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1436908_29	1385935.N836_30250	2.48e-08	67.0	COG3250@1|root,COG3250@2|Bacteria,1GD73@1117|Cyanobacteria	1117|Cyanobacteria	G	Horizontally Transferred TransMembrane Domain	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
CMS3_k127_1436908_12	502025.Hoch_2465	9.232e-75	278.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2YZ69@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS3_k127_1436908_6	1123276.KB893251_gene3627	8.267e-101	346.0	COG2041@1|root,COG2041@2|Bacteria,4NHQB@976|Bacteroidetes,47MUT@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS3_k127_1436908_17	314285.KT71_14044	6.721e-59	218.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,1RWTA@1236|Gammaproteobacteria,1J94U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1436908_24	1177179.A11A3_16375	4.267e-38	160.0	COG1309@1|root,COG1309@2|Bacteria,1NFYC@1224|Proteobacteria,1SGV5@1236|Gammaproteobacteria,1XMTN@135619|Oceanospirillales	135619|Oceanospirillales	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_10,TetR_N
CMS3_k127_1436908_9	502025.Hoch_4569	4.292e-81	291.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1436908_26	1192034.CAP_3547	3.051e-21	110.0	COG3210@1|root,COG4786@1|root,COG5184@1|root,COG3210@2|Bacteria,COG4786@2|Bacteria,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_1436908_28	215803.DB30_7320	3.016e-09	71.0	COG1506@1|root,COG2911@1|root,COG1506@2|Bacteria,COG2911@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_1436908_30	574375.BAGA_17050	7.443e-08	57.0	COG0346@1|root,COG0346@2|Bacteria,1V6K2@1239|Firmicutes,4HJ55@91061|Bacilli,1ZGBR@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS3_k127_1436908_25	743719.PaelaDRAFT_3147	6.021e-37	154.0	COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,26RQQ@186822|Paenibacillaceae	91061|Bacilli	S	acetyltransferase involved in intracellular survival and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
CMS3_k127_1436908_23	1049564.TevJSym_am00720	1.148e-38	153.0	COG1683@1|root,COG1683@2|Bacteria,1PK8Q@1224|Proteobacteria,1RXTX@1236|Gammaproteobacteria,1JB28@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
CMS3_k127_1436908_33	675817.VDA_000444	0.0002049	52.0	COG3420@1|root,COG4932@1|root,COG3420@2|Bacteria,COG4932@2|Bacteria,1PF7N@1224|Proteobacteria,1SXTD@1236|Gammaproteobacteria,1Y0AZ@135623|Vibrionales	135623|Vibrionales	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1436908_4	502025.Hoch_5810	8.54e-136	452.0	COG0006@1|root,COG0006@2|Bacteria,1MURT@1224|Proteobacteria	1224|Proteobacteria	E	Splits dipeptides with a prolyl residue in the C- terminal position	pepQ	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS3_k127_1436908_3	1123070.KB899259_gene1957	3.153e-140	457.0	COG0545@1|root,COG0545@2|Bacteria,46U5S@74201|Verrucomicrobia,2IVK3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
CMS3_k127_1436908_7	502025.Hoch_5808	1.205e-87	317.0	COG2334@1|root,COG2334@2|Bacteria,1Q18Y@1224|Proteobacteria,42PIW@68525|delta/epsilon subdivisions,2WK5A@28221|Deltaproteobacteria,2YWIH@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_1436908_5	1040983.AXAE01000035_gene2354	3.392e-105	368.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43JWG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_16,TPR_19,TPR_2
CMS3_k127_1436908_8	1340493.JNIF01000004_gene791	2.386e-84	306.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene791|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1436908_20	1121403.AUCV01000068_gene2216	2.576e-44	176.0	COG0330@1|root,COG0330@2|Bacteria,1MX2I@1224|Proteobacteria	1224|Proteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_1436908_32	163908.KB235896_gene429	0.0001777	46.0	COG0330@1|root,COG0330@2|Bacteria,1G356@1117|Cyanobacteria,1HKK1@1161|Nostocales	1117|Cyanobacteria	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_1437830_11	1121937.AUHJ01000008_gene1980	8.93e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,464NG@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8
CMS3_k127_1437830_16	746697.Aeqsu_1954	1.254e-06	58.0	COG4886@1|root,COG4886@2|Bacteria,4NFXV@976|Bacteroidetes,1I00F@117743|Flavobacteriia	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Recep_L_domain
CMS3_k127_1437830_21	1123326.JFBL01000007_gene591	0.0004524	52.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42RPP@68525|delta/epsilon subdivisions,2YP78@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	beta-lactamase activity	hcpC	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS3_k127_1437830_18	246197.MXAN_6217	1.61e-05	54.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
CMS3_k127_1437830_5	1254432.SCE1572_16255	2.732e-33	138.0	2DBX7@1|root,2ZBN4@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
CMS3_k127_1437830_2	1242864.D187_009943	1.413e-49	188.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
CMS3_k127_1437830_17	1423807.BACO01000019_gene604	9.362e-06	57.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F7I4@33958|Lactobacillaceae	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_1437830_4	1298593.TOL_2057	3.484e-44	168.0	COG0454@1|root,COG0456@2|Bacteria,1MZQ5@1224|Proteobacteria,1S45R@1236|Gammaproteobacteria,1XMKB@135619|Oceanospirillales	135619|Oceanospirillales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
CMS3_k127_1437830_19	502025.Hoch_6754	1.662e-05	57.0	COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,43CYI@68525|delta/epsilon subdivisions,2X86P@28221|Deltaproteobacteria	1224|Proteobacteria	M	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_1437830_1	269799.Gmet_3529	1.586e-50	201.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,43U0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS3_k127_1437830_8	1122164.JHWF01000043_gene1426	5.063e-23	115.0	2AP3E@1|root,31E4Y@2|Bacteria,1QBEP@1224|Proteobacteria,1T6ZP@1236|Gammaproteobacteria,1JEKJ@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1437830_13	1502852.FG94_04635	4.61e-09	63.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,476EY@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Outer membrane protein beta-barrel domain	rmpM	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,SmpA_OmlA
CMS3_k127_1437830_20	1095769.CAHF01000006_gene1807	8.391e-05	54.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria	1224|Proteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_1437830_6	742738.HMPREF9460_02288	1.021e-28	122.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,268PT@186813|unclassified Clostridiales	186801|Clostridia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1437830_3	1161401.ASJA01000006_gene1997	1.723e-45	180.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2U962@28211|Alphaproteobacteria,44026@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Cupin superfamily (DUF985)	MA20_39615	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
CMS3_k127_1437830_0	395961.Cyan7425_1861	7.46e-84	299.0	COG0604@1|root,COG0604@2|Bacteria,1GQ2K@1117|Cyanobacteria	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1437830_15	1166948.JPZL01000005_gene3318	2.118e-07	63.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,1RNPJ@1236|Gammaproteobacteria,1XHEX@135619|Oceanospirillales	135619|Oceanospirillales	K	transcriptional regulator	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
CMS3_k127_1460443_8	502025.Hoch_3711	5.736e-05	46.0	COG0823@1|root,COG0823@2|Bacteria,1PFBB@1224|Proteobacteria,432XJ@68525|delta/epsilon subdivisions,2WXKI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1460443_2	502025.Hoch_3712	1.727e-70	248.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_1460443_0	502025.Hoch_3713	0.0	1129.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Big_3_2,CARDB,F5_F8_type_C,FlgD_ig,PD40,Prenyltrans
CMS3_k127_1460443_10	1242864.D187_003759	0.0005457	52.0	COG0457@1|root,COG0457@2|Bacteria	1242864.D187_003759|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1460443_9	316067.Geob_3309	6.835e-05	56.0	COG1657@1|root,COG4932@1|root,COG1657@2|Bacteria,COG4932@2|Bacteria,1PF83@1224|Proteobacteria,430QE@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1460443_1	886293.Sinac_1156	2.39e-269	871.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1460443_5	448385.sce4289	1.68e-49	188.0	COG2267@1|root,COG2267@2|Bacteria,1QX85@1224|Proteobacteria,42W1M@68525|delta/epsilon subdivisions,2WR6V@28221|Deltaproteobacteria,2YUZN@29|Myxococcales	28221|Deltaproteobacteria	I	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_1460443_3	1304880.JAGB01000001_gene680	7.498e-61	238.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_1466508_9	1121935.AQXX01000127_gene1191	7.044e-12	76.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,1S91X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_1466508_1	391735.Veis_2921	2.563e-127	420.0	COG2267@1|root,COG2267@2|Bacteria,1QZUV@1224|Proteobacteria,2WHP2@28216|Betaproteobacteria	28216|Betaproteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1466508_3	502025.Hoch_3811	7.992e-74	256.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WMFY@28221|Deltaproteobacteria,2Z2XR@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_1466508_6	502025.Hoch_3742	1.726e-28	117.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,2YVCZ@29|Myxococcales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_1466508_0	502025.Hoch_5499	2.744e-158	509.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_1466508_2	1192034.CAP_6176	1.942e-81	285.0	COG0657@1|root,COG0657@2|Bacteria,1MVRE@1224|Proteobacteria,42XSE@68525|delta/epsilon subdivisions,2WTGG@28221|Deltaproteobacteria,2YYH0@29|Myxococcales	28221|Deltaproteobacteria	I	Pectinacetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	PAE
CMS3_k127_1466508_12	1123070.KB899254_gene1196	1.424e-07	58.0	COG5126@1|root,COG5126@2|Bacteria,46X0V@74201|Verrucomicrobia,2IWI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_1466508_8	502025.Hoch_1638	3.19e-18	96.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_1466508_11	1144275.COCOR_04089	6.831e-08	66.0	2BCR5@1|root,326BM@2|Bacteria,1QAS5@1224|Proteobacteria,43E3F@68525|delta/epsilon subdivisions,2WZKS@28221|Deltaproteobacteria,2Z2BX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1466508_7	1157490.EL26_05330	2.984e-25	115.0	COG4934@1|root,COG4934@2|Bacteria,1V06T@1239|Firmicutes,4HFKG@91061|Bacilli,2798Q@186823|Alicyclobacillaceae	91061|Bacilli	O	Pro-kumamolisin, activation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pro-kuma_activ
CMS3_k127_1466508_5	314278.NB231_09438	5.325e-37	145.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,1T11M@1236|Gammaproteobacteria,1X1AJ@135613|Chromatiales	135613|Chromatiales	S	Hemimethylated DNA-binding protein YccV like	-	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
CMS3_k127_1466508_4	502025.Hoch_0434	5.244e-66	236.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria	1224|Proteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_1521108_17	246197.MXAN_0023	4.514e-06	51.0	COG0515@1|root,COG0515@2|Bacteria	246197.MXAN_0023|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_1521108_16	1455608.JDTH01000002_gene1466	7.269e-09	64.0	COG1404@1|root,arCOG02488@1|root,arCOG07560@1|root,arCOG00702@2157|Archaea,arCOG02488@2157|Archaea,arCOG07560@2157|Archaea,2XTGN@28890|Euryarchaeota,23TTV@183963|Halobacteria	183963|Halobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,Peptidase_S8
CMS3_k127_1521108_14	1242864.D187_002676	3.059e-10	65.0	COG3793@1|root,COG3793@2|Bacteria,1PRQZ@1224|Proteobacteria,4386E@68525|delta/epsilon subdivisions,2X3GB@28221|Deltaproteobacteria,2YVYW@29|Myxococcales	28221|Deltaproteobacteria	P	PFAM Mo-dependent nitrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1521108_15	690850.Desaf_0340	4.214e-09	63.0	COG0589@1|root,COG0589@2|Bacteria,1N2H4@1224|Proteobacteria,42UE7@68525|delta/epsilon subdivisions,2WQV7@28221|Deltaproteobacteria,2MBBS@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_1521108_6	1499967.BAYZ01000104_gene3654	6.366e-64	229.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
CMS3_k127_1521108_13	1157490.EL26_04025	8.803e-17	96.0	COG3108@1|root,COG3108@2|Bacteria	2|Bacteria	S	Peptidase M15	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
CMS3_k127_1521108_12	321955.AAGP01000035_gene3475	3.181e-24	120.0	COG0791@1|root,COG5479@1|root,COG0791@2|Bacteria,COG5479@2|Bacteria,2GNDB@201174|Actinobacteria,4F9GU@85019|Brevibacteriaceae	201174|Actinobacteria	M	NlpC/P60 family	lytC	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP
CMS3_k127_1521108_4	448385.sce4070	2.126e-103	359.0	COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,42QZ4@68525|delta/epsilon subdivisions,2WUIV@28221|Deltaproteobacteria,2YUFC@29|Myxococcales	28221|Deltaproteobacteria	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
CMS3_k127_1521108_0	448385.sce8599	3.47e-148	502.0	2A4BQ@1|root,30SXD@2|Bacteria,1PCFN@1224|Proteobacteria,438EV@68525|delta/epsilon subdivisions,2WYPE@28221|Deltaproteobacteria,2YWSY@29|Myxococcales	28221|Deltaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
CMS3_k127_1521108_10	1254432.SCE1572_20660	3.444e-28	127.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_1521108_7	502025.Hoch_5811	6.43e-59	235.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1521108_8	1121354.AQUV01000002_gene746	1.188e-40	175.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,22JIY@1653|Corynebacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_1521108_1	502025.Hoch_5407	1.211e-147	481.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_1521108_18	1137799.GZ78_24985	5.651e-05	55.0	COG2706@1|root,COG2706@2|Bacteria,1NB7P@1224|Proteobacteria,1SCSF@1236|Gammaproteobacteria,1XQE5@135619|Oceanospirillales	135619|Oceanospirillales	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS3_k127_1521108_11	1192034.CAP_6467	3.79e-25	121.0	COG1262@1|root,COG1361@1|root,COG3055@1|root,COG5184@1|root,COG1262@2|Bacteria,COG1361@2|Bacteria,COG3055@2|Bacteria,COG5184@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1521108_9	1249627.D779_2931	9.365e-39	153.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1SA44@1236|Gammaproteobacteria,1X24M@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS3_k127_1521108_2	502025.Hoch_0369	7.147e-133	456.0	COG2340@1|root,COG2340@2|Bacteria,1REVB@1224|Proteobacteria,4386P@68525|delta/epsilon subdivisions,2X3GI@28221|Deltaproteobacteria,2YW01@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_1521108_3	502025.Hoch_0364	3.958e-122	402.0	COG3509@1|root,COG3509@2|Bacteria,1PI9N@1224|Proteobacteria,439C2@68525|delta/epsilon subdivisions,2X4K6@28221|Deltaproteobacteria,2YVGR@29|Myxococcales	28221|Deltaproteobacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS3_k127_154282_12	502025.Hoch_3629	1.774e-24	109.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43957@68525|delta/epsilon subdivisions,2X4BI@28221|Deltaproteobacteria,2YYP6@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS3_k127_154282_2	502025.Hoch_3628	4.721e-104	342.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,42TQ7@68525|delta/epsilon subdivisions,2WS2Q@28221|Deltaproteobacteria,2Z36A@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS3_k127_154282_13	1297742.A176_06750	1.165e-09	71.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K07279	-	-	-	-	ko00000,ko02000,ko02044	1.B.12	-	-	CBM_2,CBM_4_9,CelD_N,Cu-binding_MopE,Glyco_hydro_9,Peptidase_M66,SLH
CMS3_k127_154282_9	1192034.CAP_7491	2.59e-51	201.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Lipase_2
CMS3_k127_154282_0	502025.Hoch_3368	3.602e-127	422.0	COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YZZW@29|Myxococcales	28221|Deltaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_154282_5	502025.Hoch_3367	1.186e-89	308.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_154282_1	391625.PPSIR1_26663	7.747e-120	394.0	COG4748@1|root,COG4748@2|Bacteria,1MXDA@1224|Proteobacteria,42NFQ@68525|delta/epsilon subdivisions,2WSYJ@28221|Deltaproteobacteria,2Z1EQ@29|Myxococcales	28221|Deltaproteobacteria	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N,HSDR_N_2
CMS3_k127_154282_15	1121124.JNIX01000010_gene907	0.0002175	53.0	COG5010@1|root,COG5010@2|Bacteria,1R7S3@1224|Proteobacteria,2U39S@28211|Alphaproteobacteria,2KHNH@204458|Caulobacterales	204458|Caulobacterales	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
CMS3_k127_154282_8	580331.Thit_1470	3.459e-58	212.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_154282_10	1267533.KB906733_gene2989	3.276e-45	186.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_154282_4	215803.DB30_0019	6.676e-90	303.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2X98K@28221|Deltaproteobacteria,2Z3DJ@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_154282_6	502025.Hoch_3501	4.408e-79	270.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_154282_11	502025.Hoch_3502	3.707e-32	134.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS3_k127_154282_7	572477.Alvin_1600	4.585e-62	231.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1WXGF@135613|Chromatiales	135613|Chromatiales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS3_k127_154282_3	309801.trd_0107	3.774e-91	304.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi,27XJP@189775|Thermomicrobia	189775|Thermomicrobia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_1550512_0	1356852.N008_13920	7.296e-48	181.0	COG1075@1|root,COG1075@2|Bacteria,4NR4R@976|Bacteroidetes,47UZJ@768503|Cytophagia	976|Bacteroidetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
CMS3_k127_1567120_4	1348657.M622_04725	8.288e-21	91.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VHMS@28216|Betaproteobacteria,2KXS8@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-CoA acetyltransferase	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1567120_1	378806.STAUR_6882	6.717e-78	273.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
CMS3_k127_1567120_2	211165.AJLN01000104_gene6520	2.97e-61	230.0	COG1309@1|root,COG1309@2|Bacteria,1G5HM@1117|Cyanobacteria,1JI00@1189|Stigonemataceae	1117|Cyanobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_C_13,TetR_C_6,TetR_N
CMS3_k127_1567120_3	448385.sce3213	6.697e-53	202.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,431FI@68525|delta/epsilon subdivisions,2WX1E@28221|Deltaproteobacteria,2YV8K@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_1567120_6	8128.ENSONIP00000021045	1.333e-07	64.0	COG0666@1|root,KOG0504@2759|Eukaryota,39YNX@33154|Opisthokonta,3B9NB@33208|Metazoa,3CRFJ@33213|Bilateria,47ZCI@7711|Chordata,48Y1R@7742|Vertebrata,4A23D@7898|Actinopterygii	33208|Metazoa	O	ankyrin repeat	ANKRD52	-	-	ko:K15502,ko:K15504	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
CMS3_k127_1567120_0	404589.Anae109_0766	7.957e-106	372.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria	1224|Proteobacteria	P	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_1581095_6	502025.Hoch_3677	1.235e-33	136.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_3677|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1581095_1	502025.Hoch_3676	2.427e-191	624.0	COG1413@1|root,COG1413@2|Bacteria,1RK8P@1224|Proteobacteria,42VXW@68525|delta/epsilon subdivisions,2WRH4@28221|Deltaproteobacteria,2Z1BY@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_1581095_4	502025.Hoch_3675	1.096e-56	204.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1581095_2	502025.Hoch_3605	7.852e-172	553.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2YURF@29|Myxococcales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS3_k127_1581095_7	290397.Adeh_1501	9.119e-23	114.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2Z1VF@29|Myxococcales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_1581095_0	502025.Hoch_3604	3.713e-193	613.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,2YU3G@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_1581095_3	326427.Cagg_0670	1.632e-97	335.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
CMS3_k127_1606929_9	1111730.ATTM01000002_gene1289	5.797e-06	56.0	2D7E4@1|root,32TNW@2|Bacteria,4NSYH@976|Bacteroidetes,1I4B8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4476
CMS3_k127_1606929_0	391625.PPSIR1_33194	4.005e-160	529.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,42S4X@68525|delta/epsilon subdivisions,2WNPW@28221|Deltaproteobacteria,2YU9Y@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M13	-	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
CMS3_k127_1606929_1	1254432.SCE1572_49150	1.056e-99	347.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria	1224|Proteobacteria	M	Spore Coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Cu-binding_MopE,Lectin_C
CMS3_k127_1606929_10	378806.STAUR_3843	1.977e-05	55.0	COG0810@1|root,COG1716@1|root,COG0810@2|Bacteria,COG1716@2|Bacteria,1QX84@1224|Proteobacteria,430UC@68525|delta/epsilon subdivisions,2WVSU@28221|Deltaproteobacteria,2YYAP@29|Myxococcales	28221|Deltaproteobacteria	MT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
CMS3_k127_1606929_7	861299.J421_4378	6.563e-25	114.0	COG3595@1|root,COG3595@2|Bacteria,1ZTQ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_1606929_6	391625.PPSIR1_35672	2.186e-27	128.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD
CMS3_k127_1606929_4	378806.STAUR_6882	7.001e-71	252.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
CMS3_k127_1606929_2	1121271.AUCM01000008_gene3194	1.059e-78	283.0	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,2U0YM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	zf-RRN7
CMS3_k127_1606929_3	502025.Hoch_0497	1.08e-76	274.0	COG0515@1|root,COG3416@1|root,COG0515@2|Bacteria,COG3416@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_1606929_8	502025.Hoch_0363	4.141e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1PXHP@1224|Proteobacteria,434K6@68525|delta/epsilon subdivisions,2WYXE@28221|Deltaproteobacteria,2Z0V1@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16
CMS3_k127_1607051_4	396588.Tgr7_2176	1.199e-98	333.0	COG0547@1|root,COG0547@2|Bacteria,1QDR6@1224|Proteobacteria,1T9UH@1236|Gammaproteobacteria,1WW56@135613|Chromatiales	135613|Chromatiales	E	PFAM Glycosyl transferase, family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS3_k127_1607051_9	404380.Gbem_1799	3.663e-07	63.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,fn3
CMS3_k127_1607051_8	1283299.AUKG01000002_gene3894	1.843e-11	74.0	COG1943@1|root,COG1943@2|Bacteria,2H8SG@201174|Actinobacteria,4CTGI@84995|Rubrobacteria	84995|Rubrobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_1607051_3	502025.Hoch_4706	2.32e-100	336.0	COG0614@1|root,COG0614@2|Bacteria,1PK1H@1224|Proteobacteria,433XB@68525|delta/epsilon subdivisions,2X3Z2@28221|Deltaproteobacteria,2YXNE@29|Myxococcales	28221|Deltaproteobacteria	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
CMS3_k127_1607051_10	215803.DB30_4298	1.023e-06	61.0	COG4447@1|root,COG4447@2|Bacteria,1PK4F@1224|Proteobacteria,437G7@68525|delta/epsilon subdivisions,2XA3A@28221|Deltaproteobacteria,2YVKV@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1607051_1	1379698.RBG1_1C00001G1403	2.263e-115	386.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
CMS3_k127_1607051_2	502025.Hoch_4707	3.389e-104	346.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,434HT@68525|delta/epsilon subdivisions,2WYV2@28221|Deltaproteobacteria,2Z0PY@29|Myxococcales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_1607051_6	502025.Hoch_4940	2.787e-43	166.0	2E4IQ@1|root,32ZDS@2|Bacteria,1NBEP@1224|Proteobacteria,431T4@68525|delta/epsilon subdivisions,2WW82@28221|Deltaproteobacteria,2YVWC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1607051_5	439235.Dalk_3036	8.849e-71	253.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WN2R@28221|Deltaproteobacteria,2MMYS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS3_k127_1607051_0	1254432.SCE1572_21885	7.102e-161	518.0	COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,439ZZ@68525|delta/epsilon subdivisions,2X4EZ@28221|Deltaproteobacteria,2YYW8@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.77,1.2.1.91,3.3.2.12	ko:K02618,ko:K15514	ko00360,ko00362,ko01120,map00360,map00362,map01120	-	R09554,R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_1639091_0	404589.Anae109_4238	5.37e-63	227.0	COG2030@1|root,COG2030@2|Bacteria,1RJN8@1224|Proteobacteria	1224|Proteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_1639091_1	1144275.COCOR_07596	1.202e-41	161.0	COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,43B73@68525|delta/epsilon subdivisions,2X6KK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_1639091_2	1254432.SCE1572_11160	7.718e-10	63.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_1659207_10	1267535.KB906767_gene2246	3.546e-28	116.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria,2JIWQ@204432|Acidobacteriia	204432|Acidobacteriia	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS3_k127_1659207_3	448385.sce5335	1.704e-116	392.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2YZNI@29|Myxococcales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
CMS3_k127_1659207_8	448385.sce5334	4.094e-32	144.0	COG1030@1|root,COG1030@2|Bacteria,1MY7A@1224|Proteobacteria,42SJX@68525|delta/epsilon subdivisions,2WPDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS3_k127_1659207_1	448385.sce5333	1.46e-136	441.0	COG4864@1|root,COG4864@2|Bacteria,1MWP0@1224|Proteobacteria,42N9I@68525|delta/epsilon subdivisions,2WK7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS3_k127_1659207_4	448385.sce5332	2.685e-101	350.0	2DBR9@1|root,2ZAJD@2|Bacteria,1R7F3@1224|Proteobacteria,435AD@68525|delta/epsilon subdivisions,2WZME@28221|Deltaproteobacteria,2Z2DE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1659207_7	502025.Hoch_6006	1.356e-42	168.0	COG0746@1|root,COG0746@2|Bacteria,1Q8KG@1224|Proteobacteria,4347M@68525|delta/epsilon subdivisions,2X9X3@28221|Deltaproteobacteria,2Z228@29|Myxococcales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_1659207_2	502025.Hoch_6005	1.841e-133	433.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS3_k127_1659207_6	1125863.JAFN01000001_gene1060	1.144e-43	173.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_1659207_0	1278073.MYSTI_04825	1.638e-220	696.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,43AK6@68525|delta/epsilon subdivisions,2WV5N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
CMS3_k127_1659207_9	1121924.ATWH01000004_gene2316	1.631e-28	122.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
CMS3_k127_1659207_5	1440774.Y900_011300	1.959e-52	198.0	COG1028@1|root,COG1028@2|Bacteria,2HRAZ@201174|Actinobacteria,23DE9@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_1671994_12	502025.Hoch_5993	1.149e-45	167.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42MUA@68525|delta/epsilon subdivisions,2WJWH@28221|Deltaproteobacteria,2YWF4@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_1671994_5	502025.Hoch_5992	3.845e-99	342.0	COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,42MGW@68525|delta/epsilon subdivisions,2WJQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
CMS3_k127_1671994_8	404589.Anae109_2865	3.332e-55	202.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,42XV1@68525|delta/epsilon subdivisions,2WSUD@28221|Deltaproteobacteria,2YV76@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_1671994_11	862908.BMS_0211	4.1e-53	194.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,42RCU@68525|delta/epsilon subdivisions,2MT7P@213481|Bdellovibrionales,2WMXY@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
CMS3_k127_1671994_6	404589.Anae109_2862	3.008e-76	267.0	COG1622@1|root,COG1622@2|Bacteria,1MVYW@1224|Proteobacteria,42R2B@68525|delta/epsilon subdivisions,2WN74@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c oxidase subunit	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
CMS3_k127_1671994_1	404589.Anae109_2861	1.241e-236	745.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions,2WJUK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS3_k127_1671994_13	404589.Anae109_2860	7.223e-45	169.0	COG1845@1|root,COG1845@2|Bacteria,1Q5H6@1224|Proteobacteria,4318V@68525|delta/epsilon subdivisions,2WWEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS3_k127_1671994_9	404589.Anae109_2859	7.146e-55	207.0	COG2010@1|root,COG2010@2|Bacteria,1R03D@1224|Proteobacteria,43CQJ@68525|delta/epsilon subdivisions,2X7Y0@28221|Deltaproteobacteria,2Z1XC@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_1671994_14	525904.Tter_0120	1.374e-25	124.0	COG1670@1|root,COG1670@2|Bacteria,2NPXX@2323|unclassified Bacteria	2|Bacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_1671994_3	502025.Hoch_4569	4.918e-127	425.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1671994_10	1219084.AP014508_gene96	3.289e-53	201.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_1671994_0	502025.Hoch_4797	0.0	1227.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1MWVZ@1224|Proteobacteria,438G1@68525|delta/epsilon subdivisions,2X3QZ@28221|Deltaproteobacteria,2YWVV@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
CMS3_k127_1671994_7	502025.Hoch_4796	5.814e-73	281.0	2BQU7@1|root,32JQZ@2|Bacteria,1Q2FE@1224|Proteobacteria,4381B@68525|delta/epsilon subdivisions,2X05S@28221|Deltaproteobacteria,2YV8M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_FA
CMS3_k127_1671994_2	502025.Hoch_4795	3.507e-203	642.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2WJWZ@28221|Deltaproteobacteria,2YUKJ@29|Myxococcales	28221|Deltaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2,4.3.1.1	ko:K01679,ko:K01744	ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R00490,R01082	RC00316,RC00443,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS3_k127_1671994_4	502025.Hoch_5811	4.998e-113	389.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1671994_17	1009370.ALO_11059	1.878e-07	61.0	2C7A5@1|root,33FXS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1671994_15	448385.sce6597	2.422e-20	96.0	2E5WH@1|root,330KI@2|Bacteria,1QAVR@1224|Proteobacteria,435BU@68525|delta/epsilon subdivisions,2WZPC@28221|Deltaproteobacteria,2Z2GK@29|Myxococcales	28221|Deltaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS3_k127_1686844_0	502025.Hoch_4637	6.15e-202	644.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,2YU50@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
CMS3_k127_1686844_1	502025.Hoch_4636	5.069e-73	247.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
CMS3_k127_1691117_9	1234364.AMSF01000033_gene326	1.72e-09	60.0	COG3571@1|root,COG3571@2|Bacteria,1R1FA@1224|Proteobacteria,1T50H@1236|Gammaproteobacteria,1XDAX@135614|Xanthomonadales	135614|Xanthomonadales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1691117_0	215803.DB30_6435	1.294e-234	756.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,437F0@68525|delta/epsilon subdivisions,2XA2R@28221|Deltaproteobacteria,2YTSS@29|Myxococcales	28221|Deltaproteobacteria	E	ERAP1-like C-terminal domain	-	-	3.4.11.14	ko:K01263	-	-	-	-	ko00000,ko01000	-	-	-	ERAP1_C,Peptidase_M1
CMS3_k127_1691117_2	886293.Sinac_1156	6.752e-204	680.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_1691117_8	1156844.KB891842_gene7189	7.278e-10	64.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_1691117_7	1380387.JADM01000007_gene748	5.313e-28	121.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_1691117_6	452637.Oter_0564	6.418e-42	162.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	pgm3	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS3_k127_1691117_10	880073.Calab_3269	3.116e-08	65.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K04739,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko04910,ko05111,map02020,map02024,map02025,map02026,map04910,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
CMS3_k127_1691117_1	1192034.CAP_8282	8.29e-212	673.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YTZ2@29|Myxococcales	28221|Deltaproteobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_1691117_3	1254432.SCE1572_09530	2.78e-127	449.0	COG0477@1|root,COG2814@2|Bacteria,1MWKH@1224|Proteobacteria,43AQN@68525|delta/epsilon subdivisions,2X64N@28221|Deltaproteobacteria,2Z2K7@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08178	-	-	-	-	ko00000,ko02000	2.A.1.12	-	-	MFS_1
CMS3_k127_1691117_5	448385.sce6858	9.637e-76	266.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,438M3@68525|delta/epsilon subdivisions,2X1ZS@28221|Deltaproteobacteria,2YX8A@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
CMS3_k127_1714818_0	502025.Hoch_3173	7.674e-211	689.0	COG1196@1|root,COG1196@2|Bacteria,1QX9X@1224|Proteobacteria,43018@68525|delta/epsilon subdivisions,2WVD9@28221|Deltaproteobacteria,2YW2N@29|Myxococcales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
CMS3_k127_1714818_2	502025.Hoch_4931	1.799e-88	296.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1714818_1	502025.Hoch_4619	3.441e-110	377.0	COG0744@1|root,COG2982@1|root,COG0744@2|Bacteria,COG2982@2|Bacteria,1RDAQ@1224|Proteobacteria,42QW6@68525|delta/epsilon subdivisions,2WPZA@28221|Deltaproteobacteria,2YVC6@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS3_k127_173224_3	1535422.ND16A_2888	7.634e-25	107.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,2Q6PY@267889|Colwelliaceae	1236|Gammaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
CMS3_k127_173224_0	502025.Hoch_6457	1.103e-75	263.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WPJ6@28221|Deltaproteobacteria,2Z2ZH@29|Myxococcales	28221|Deltaproteobacteria	H	molybdenum cofactor biosynthesis protein B	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS3_k127_173224_2	3694.POPTR_0019s09220.1	2.622e-37	148.0	COG0216@1|root,KOG2726@2759|Eukaryota,37SSY@33090|Viridiplantae,3G9BB@35493|Streptophyta,4JNVI@91835|fabids	35493|Streptophyta	J	Peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
CMS3_k127_173224_1	1297742.A176_06055	2.815e-44	170.0	COG0625@1|root,COG0625@2|Bacteria,1QA0M@1224|Proteobacteria,434R5@68525|delta/epsilon subdivisions,2WZ2A@28221|Deltaproteobacteria,2Z169@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
CMS3_k127_173224_4	1304275.C41B8_02132	1.182e-13	74.0	COG1073@1|root,COG1073@2|Bacteria,1QWRH@1224|Proteobacteria,1T2XF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0227
CMS3_k127_1739722_12	1192034.CAP_8873	5.309e-17	93.0	COG1716@1|root,COG1716@2|Bacteria,1PCHK@1224|Proteobacteria,438FP@68525|delta/epsilon subdivisions,2X3QN@28221|Deltaproteobacteria,2YWV4@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS3_k127_1739722_11	1123242.JH636434_gene4961	4.397e-40	172.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_1739722_13	215803.DB30_5181	1.708e-16	91.0	COG0457@1|root,COG0457@2|Bacteria	215803.DB30_5181|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1739722_1	502025.Hoch_1902	1.607e-159	531.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2YUX0@29|Myxococcales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_1739722_3	502025.Hoch_1904	1.389e-132	450.0	COG3266@1|root,COG3266@2|Bacteria,1PBVF@1224|Proteobacteria,4384T@68525|delta/epsilon subdivisions,2X3EV@28221|Deltaproteobacteria,2YVRI@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
CMS3_k127_1739722_8	404589.Anae109_1826	1.689e-62	231.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
CMS3_k127_1739722_2	502025.Hoch_4438	2.169e-158	517.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
CMS3_k127_1739722_5	502025.Hoch_4437	5.286e-97	344.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_1739722_0	502025.Hoch_4435	8.215e-292	918.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YUHY@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
CMS3_k127_1739722_7	502025.Hoch_4434	4.145e-81	276.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,42U7C@68525|delta/epsilon subdivisions,2WQM9@28221|Deltaproteobacteria,2Z33Z@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS3_k127_1739722_4	391625.PPSIR1_02191	1.267e-113	379.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS3_k127_1739722_6	1192034.CAP_1511	4.549e-94	332.0	COG0265@1|root,COG0515@1|root,COG3287@1|root,COG0265@2|Bacteria,COG0515@2|Bacteria,COG3287@2|Bacteria,1PEIZ@1224|Proteobacteria,433VS@68525|delta/epsilon subdivisions,2X3Q2@28221|Deltaproteobacteria,2YWTJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PDZ_2,Pkinase
CMS3_k127_1739722_15	314345.SPV1_03883	4.757e-07	61.0	297U0@1|root,2ZV0P@2|Bacteria,1P6ZH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1739722_14	502025.Hoch_4619	2.969e-07	55.0	COG0744@1|root,COG2982@1|root,COG0744@2|Bacteria,COG2982@2|Bacteria,1RDAQ@1224|Proteobacteria,42QW6@68525|delta/epsilon subdivisions,2WPZA@28221|Deltaproteobacteria,2YVC6@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS3_k127_1759879_0	1123508.JH636445_gene6576	1.392e-71	263.0	COG2931@1|root,COG3209@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
CMS3_k127_1759879_2	91464.S7335_5095	5.777e-13	82.0	COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria,1H0CR@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,FG-GAP,HemolysinCabind
CMS3_k127_1759879_1	1458357.BG58_22570	3.885e-30	122.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VHP1@28216|Betaproteobacteria,1K4GC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE1	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_C,Transketolase_N
CMS3_k127_1767601_5	1184267.A11Q_134	1.564e-63	222.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2MSR9@213481|Bdellovibrionales,2WJDF@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_1767601_3	502025.Hoch_5315	3.454e-78	266.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2YV1Q@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS3_k127_1767601_0	502025.Hoch_5316	7.425e-152	501.0	COG0515@1|root,COG0515@2|Bacteria,1Q389@1224|Proteobacteria,438Z3@68525|delta/epsilon subdivisions,2X44E@28221|Deltaproteobacteria,2YY87@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,Pkinase
CMS3_k127_1767601_1	880073.Calab_3204	6.371e-123	422.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_1767601_9	1384056.N787_02210	6.786e-07	58.0	COG1638@1|root,COG1638@2|Bacteria,1PBU6@1224|Proteobacteria,1RXK0@1236|Gammaproteobacteria,1X5NG@135614|Xanthomonadales	135614|Xanthomonadales	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_1767601_10	566466.NOR53_2704	1.929e-06	56.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
CMS3_k127_1767601_6	502025.Hoch_5502	1.309e-47	179.0	COG1051@1|root,COG1051@2|Bacteria,1QUNH@1224|Proteobacteria,43C4F@68525|delta/epsilon subdivisions,2WS06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_1767601_11	1189612.A33Q_1404	2.456e-05	57.0	COG5492@1|root,COG5492@2|Bacteria,4NSH8@976|Bacteroidetes,47N9P@768503|Cytophagia	976|Bacteroidetes	N	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD
CMS3_k127_1767601_2	1192034.CAP_3725	1.027e-93	314.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YYDX@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
CMS3_k127_1767601_8	502025.Hoch_2113	1.3e-41	158.0	COG1327@1|root,COG1327@2|Bacteria	502025.Hoch_2113|-	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1767601_4	502025.Hoch_2111	3.762e-76	259.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42QRT@68525|delta/epsilon subdivisions,2WMPW@28221|Deltaproteobacteria,2YVT0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_178703_1	502025.Hoch_0307	5.035e-108	365.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2X9QV@28221|Deltaproteobacteria,2Z1C8@29|Myxococcales	28221|Deltaproteobacteria	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_178703_6	649638.Trad_0440	4.346e-12	77.0	COG0457@1|root,COG0457@2|Bacteria	649638.Trad_0440|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_178703_4	1121456.ATVA01000014_gene757	3.64e-34	142.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,2MAZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS3_k127_178703_3	290397.Adeh_2824	1.788e-35	156.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,42QS0@68525|delta/epsilon subdivisions,2WMU6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS3_k127_178703_0	1502770.JQMG01000001_gene1735	6.154e-135	445.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,2KM4A@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS3_k127_1810494_1	1121373.KB903644_gene3387	3.11e-96	319.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47NU9@768503|Cytophagia	976|Bacteroidetes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1810494_0	469383.Cwoe_3478	4.331e-116	389.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_1810494_10	1232437.KL661959_gene3108	2.965e-12	80.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria,2MPWS@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
CMS3_k127_1810494_5	1242864.D187_008666	4.329e-28	128.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WIMQ@28221|Deltaproteobacteria,2YYKM@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	CarS-like,Metallophos
CMS3_k127_1810494_11	1499967.BAYZ01000056_gene4881	3.841e-12	79.0	COG2067@1|root,COG2067@2|Bacteria,2NPN1@2323|unclassified Bacteria	2|Bacteria	I	Membrane protein involved in aromatic hydrocarbon degradation	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_1810494_4	391625.PPSIR1_00090	8.137e-36	142.0	COG1595@1|root,COG1595@2|Bacteria,1N4RS@1224|Proteobacteria,43E0K@68525|delta/epsilon subdivisions,2WZCJ@28221|Deltaproteobacteria,2Z1UN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1810494_9	688270.Celal_0317	1.541e-13	78.0	COG5384@1|root,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes,1IKB1@117743|Flavobacteriia,1F9ZS@104264|Cellulophaga	976|Bacteroidetes	J	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,TSP_3
CMS3_k127_1810494_3	656024.FsymDg_1317	1.303e-37	150.0	COG0236@1|root,COG2070@1|root,COG3321@1|root,COG0236@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4EU82@85013|Frankiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_1811096_4	1121481.AUAS01000005_gene2141	1.236e-99	329.0	COG3934@1|root,COG3934@2|Bacteria,4NFVS@976|Bacteroidetes,47KA9@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS3_k127_1811096_0	502025.Hoch_6732	6.043e-271	841.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YU6I@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_1811096_6	502025.Hoch_0439	3.556e-91	311.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1811096_3	502025.Hoch_0440	2.025e-114	394.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_1811096_5	1128421.JAGA01000002_gene1381	1.329e-96	360.0	COG0624@1|root,COG0624@2|Bacteria,2NQ4M@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42
CMS3_k127_1811096_14	1323361.JPOC01000066_gene47	6.285e-07	62.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4G0TI@85025|Nocardiaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS3_k127_1811096_12	502025.Hoch_5823	1.043e-17	92.0	COG1555@1|root,COG1555@2|Bacteria,1Q1BE@1224|Proteobacteria,43764@68525|delta/epsilon subdivisions,2X24M@28221|Deltaproteobacteria,2Z2UP@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
CMS3_k127_1811096_11	404589.Anae109_2853	3.108e-18	99.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1811096_7	502025.Hoch_5758	3.218e-63	224.0	2AQXT@1|root,31G6D@2|Bacteria,1QACF@1224|Proteobacteria,434ZG@68525|delta/epsilon subdivisions,2WZA9@28221|Deltaproteobacteria,2Z1PG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
CMS3_k127_1811096_2	502025.Hoch_5754	2.914e-138	464.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,42QIS@68525|delta/epsilon subdivisions,2WMK0@28221|Deltaproteobacteria,2YV96@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
CMS3_k127_1811096_1	502025.Hoch_5753	1.057e-145	468.0	COG2378@1|root,COG2378@2|Bacteria,1QAGU@1224|Proteobacteria,434D3@68525|delta/epsilon subdivisions,2WYQ2@28221|Deltaproteobacteria,2Z0CG@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
CMS3_k127_181858_7	1192034.CAP_4132	8.177e-82	281.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2YX41@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_181858_5	1254432.SCE1572_37950	8.443e-93	310.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS3_k127_181858_1	1121920.AUAU01000009_gene1860	1.296e-147	480.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS3_k127_181858_3	404589.Anae109_2407	7.872e-128	426.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria,2YWQF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
CMS3_k127_181858_9	1232410.KI421424_gene1760	6.34e-46	181.0	COG2010@1|root,COG2010@2|Bacteria,1QYFZ@1224|Proteobacteria,43CC3@68525|delta/epsilon subdivisions,2WQTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_181858_6	502025.Hoch_6281	7.359e-86	309.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
CMS3_k127_181858_11	1403819.BATR01000094_gene3017	8.087e-05	49.0	29NNP@1|root,309KM@2|Bacteria,46WPF@74201|Verrucomicrobia,2IUZE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_181858_2	1192034.CAP_2520	5.451e-129	428.0	COG1073@1|root,COG1073@2|Bacteria,1NSQP@1224|Proteobacteria,438M1@68525|delta/epsilon subdivisions,2X27G@28221|Deltaproteobacteria,2YX84@29|Myxococcales	28221|Deltaproteobacteria	S	PS-10 peptidase S37	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S37
CMS3_k127_181858_8	502025.Hoch_4720	2.233e-76	277.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Kelch_1,Kelch_4,Kelch_6
CMS3_k127_181858_10	502025.Hoch_4719	1.276e-16	92.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS3_k127_181858_4	502025.Hoch_4718	1.337e-104	349.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
CMS3_k127_181858_0	502025.Hoch_2308	2.793e-152	486.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria,2YUM5@29|Myxococcales	28221|Deltaproteobacteria	E	Sarcosine oxidase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
CMS3_k127_1839479_0	1192034.CAP_4237	1.446e-185	585.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,42ZRT@68525|delta/epsilon subdivisions,2WUTK@28221|Deltaproteobacteria,2YY3I@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1839479_3	1192034.CAP_4238	1.661e-131	429.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria,2YYYG@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1839479_13	1278073.MYSTI_00206	4.493e-51	207.0	COG0682@1|root,COG0682@2|Bacteria,1Q2R4@1224|Proteobacteria,438CQ@68525|delta/epsilon subdivisions,2WP0G@28221|Deltaproteobacteria,2YWK4@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_1839479_8	330084.JNYZ01000032_gene5505	2.607e-72	259.0	COG4399@1|root,COG4399@2|Bacteria,2GMW6@201174|Actinobacteria,4E0Z2@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
CMS3_k127_1839479_18	448385.sce5856	1.132e-17	90.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_1839479_7	1313172.YM304_12950	1.961e-81	289.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMRN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_1839479_20	391625.PPSIR1_20539	3.726e-13	80.0	COG0697@1|root,COG0697@2|Bacteria,1Q24K@1224|Proteobacteria,437RU@68525|delta/epsilon subdivisions,2X30K@28221|Deltaproteobacteria,2Z2P4@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_1839479_21	290400.Jann_2010	9.356e-09	63.0	2EJE4@1|root,33D54@2|Bacteria,1NJDC@1224|Proteobacteria,2UQQR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1839479_5	502025.Hoch_5811	1.97e-94	351.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1839479_11	502025.Hoch_0117	4.459e-62	245.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	spoIID	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
CMS3_k127_1839479_4	502025.Hoch_6645	1.376e-118	392.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YZKE@29|Myxococcales	28221|Deltaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_1839479_12	1205680.CAKO01000008_gene4111	6.313e-61	218.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,2JVKT@204441|Rhodospirillales	204441|Rhodospirillales	K	Sir2 family	-	-	-	-	-	-	-	-	-	-	-	-	SIR2
CMS3_k127_1839479_6	4952.CAG82336	6.923e-91	310.0	COG0657@1|root,KOG1515@2759|Eukaryota,3A1CU@33154|Opisthokonta,3NZ98@4751|Fungi,3QKHV@4890|Ascomycota,3RVXJ@4891|Saccharomycetes	4751|Fungi	V	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_1839479_9	935863.AWZR01000007_gene259	1.439e-68	242.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_1839479_1	502025.Hoch_6646	3.323e-173	557.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_1839479_2	502025.Hoch_6647	6.127e-148	500.0	COG0457@1|root,COG0457@2|Bacteria,1QZTW@1224|Proteobacteria,43CNX@68525|delta/epsilon subdivisions,2X7W7@28221|Deltaproteobacteria,2Z2GV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_1839479_10	502025.Hoch_4717	4.029e-63	235.0	COG2821@1|root,COG2821@2|Bacteria,1NIC3@1224|Proteobacteria,433CJ@68525|delta/epsilon subdivisions,2WXQG@28221|Deltaproteobacteria,2Z1V4@29|Myxococcales	28221|Deltaproteobacteria	M	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
CMS3_k127_1839479_15	1214242.B446_22030	3.884e-33	136.0	COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria	201174|Actinobacteria	Q	catechol 1,2-dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
CMS3_k127_1839479_16	338966.Ppro_1168	1.058e-24	111.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,43UWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_1839479_14	671143.DAMO_2088	4.332e-47	178.0	COG2087@1|root,COG2087@2|Bacteria,2NRKT@2323|unclassified Bacteria	2|Bacteria	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568	2.7.1.156,2.7.7.62,6.3.5.10	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R05225,R06558	RC00002,RC00010,RC00428,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_2074,iECSE_1348.ECSE_2277,iECW_1372.ECW_m2165,iETEC_1333.ETEC_2103,iEcE24377_1341.EcE24377A_2275,iEcSMS35_1347.EcSMS35_1131,iEcolC_1368.EcolC_1635,iLF82_1304.LF82_0337,iSDY_1059.SDY_2240,iWFL_1372.ECW_m2165	CobU
CMS3_k127_1839479_17	1120999.JONM01000037_gene2106	9.398e-19	96.0	2AWRE@1|root,31NNC@2|Bacteria,1MYIQ@1224|Proteobacteria,2W2EV@28216|Betaproteobacteria,2KSYI@206351|Neisseriales	206351|Neisseriales	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CMS3_k127_1839479_19	1042375.AFPL01000038_gene1584	2.409e-17	86.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,464PE@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.71	ko:K00128,ko:K06447	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_1849552_5	1101188.KI912155_gene1939	1.155e-37	142.0	COG2030@1|root,COG2030@2|Bacteria,2IK2Z@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_1849552_0	502025.Hoch_0099	1.543e-172	570.0	COG1413@1|root,COG1413@2|Bacteria,1QX4H@1224|Proteobacteria,42Z02@68525|delta/epsilon subdivisions,2WUJ9@28221|Deltaproteobacteria,2YVP1@29|Myxococcales	28221|Deltaproteobacteria	C	Type II secretion system (T2SS), protein E, N-terminal domain	frgA	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,T2SSE_N
CMS3_k127_1849552_3	502025.Hoch_0098	2.807e-57	205.0	COG1714@1|root,COG1714@2|Bacteria,1NJQW@1224|Proteobacteria,4375K@68525|delta/epsilon subdivisions,2X41F@28221|Deltaproteobacteria,2YXYC@29|Myxococcales	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS3_k127_1849552_4	502025.Hoch_0097	3.621e-53	207.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,42R1A@68525|delta/epsilon subdivisions,2WMV6@28221|Deltaproteobacteria,2YVVD@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS3_k127_1849552_2	502025.Hoch_0096	6.548e-70	246.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WIVV@28221|Deltaproteobacteria,2Z2ZT@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS3_k127_1849552_1	502025.Hoch_0095	3.6e-108	358.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_1883929_1	502025.Hoch_2145	1.996e-76	261.0	COG1595@1|root,COG1595@2|Bacteria,1QAB8@1224|Proteobacteria,434YB@68525|delta/epsilon subdivisions,2WZ98@28221|Deltaproteobacteria,2Z1MI@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1883929_4	502025.Hoch_2143	1.627e-33	136.0	2A4WF@1|root,30TI4@2|Bacteria,1PDD5@1224|Proteobacteria,435F2@68525|delta/epsilon subdivisions,2WZSM@28221|Deltaproteobacteria,2Z2NW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1883929_3	502025.Hoch_2141	3.161e-49	193.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_1883929_0	502025.Hoch_2136	5.184e-106	349.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2YV41@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_188408_1	269799.Gmet_0726	5.651e-18	87.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,42UGM@68525|delta/epsilon subdivisions,2WQR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_188408_0	1278073.MYSTI_06549	9.324e-38	160.0	2AIV6@1|root,319CD@2|Bacteria,1Q2BD@1224|Proteobacteria,437XV@68525|delta/epsilon subdivisions,2X37S@28221|Deltaproteobacteria,2YUR7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1904685_22	404589.Anae109_4241	1.161e-68	240.0	COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,43AKT@68525|delta/epsilon subdivisions,2X60V@28221|Deltaproteobacteria,2Z23B@29|Myxococcales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_1904685_13	404589.Anae109_4239	1.582e-114	399.0	COG0654@1|root,COG0654@2|Bacteria,1R03K@1224|Proteobacteria,43CQQ@68525|delta/epsilon subdivisions,2X7Y6@28221|Deltaproteobacteria,2Z1K0@29|Myxococcales	28221|Deltaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_1904685_9	404589.Anae109_4240	2.188e-141	463.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,437TD@68525|delta/epsilon subdivisions,2WT6I@28221|Deltaproteobacteria,2YX1E@29|Myxococcales	28221|Deltaproteobacteria	C	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
CMS3_k127_1904685_42	1502851.FG93_03411	8.182e-10	64.0	2C1W2@1|root,31MWG@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_1904685_32	1307759.JOMJ01000003_gene1541	2.928e-27	128.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	fleS	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Pkinase,Response_reg
CMS3_k127_1904685_12	640511.BC1002_5570	2.321e-122	429.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
CMS3_k127_1904685_38	1121939.L861_01750	4.765e-19	93.0	2C1W2@1|root,31MWG@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_1904685_28	1340493.JNIF01000004_gene791	1.061e-45	190.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000004_gene791|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1904685_16	452637.Oter_4629	5.543e-101	353.0	COG0784@1|root,COG3447@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3447@2|Bacteria,COG4191@2|Bacteria,46U18@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_3,Response_reg
CMS3_k127_1904685_39	1403819.BATR01000169_gene5823	1.005e-18	100.0	COG3203@1|root,COG3203@2|Bacteria,46SY8@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS3_k127_1904685_4	626939.HMPREF9443_00167	2.394e-192	614.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4H1XW@909932|Negativicutes	909932|Negativicutes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS3_k127_1904685_45	1280380.KR100_11025	0.0001006	53.0	COG3794@1|root,COG3794@2|Bacteria,1G6Z2@1117|Cyanobacteria,1H0FG@1129|Synechococcus	1117|Cyanobacteria	C	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I	petE	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
CMS3_k127_1904685_21	502025.Hoch_6056	1.564e-82	289.0	COG0515@1|root,COG0515@2|Bacteria,1Q31E@1224|Proteobacteria,438RJ@68525|delta/epsilon subdivisions,2X991@28221|Deltaproteobacteria,2YXKM@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1904685_44	1122609.AUGT01000027_gene2765	1.368e-05	59.0	COG1394@1|root,COG1394@2|Bacteria	2|Bacteria	C	ATPase activity, coupled to transmembrane movement of substances	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
CMS3_k127_1904685_7	404589.Anae109_2563	9.258e-151	514.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_1904685_5	290397.Adeh_1202	8.649e-188	608.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
CMS3_k127_1904685_46	1121945.ATXS01000007_gene425	0.0005388	52.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,23THJ@183963|Halobacteria	183963|Halobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
CMS3_k127_1904685_40	443143.GM18_2448	4.454e-16	83.0	COG0636@1|root,COG0636@2|Bacteria,1N5D3@1224|Proteobacteria,438SF@68525|delta/epsilon subdivisions,2WY87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM H transporting two-sector ATPase C subunit	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
CMS3_k127_1904685_18	290397.Adeh_1197	4.943e-89	322.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
CMS3_k127_1904685_8	1125863.JAFN01000001_gene3576	5.22e-143	465.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hyaS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3332	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
CMS3_k127_1904685_1	357808.RoseRS_2320	1.319e-260	812.0	COG0374@1|root,COG0374@2|Bacteria,2G6SF@200795|Chloroflexi,376Y8@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
CMS3_k127_1904685_24	1121918.ARWE01000001_gene3503	6.757e-54	202.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2X8MJ@28221|Deltaproteobacteria,43TMS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS3_k127_1904685_29	1121033.AUCF01000027_gene2775	1.505e-39	154.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2U2IN@28211|Alphaproteobacteria,2JT4C@204441|Rhodospirillales	204441|Rhodospirillales	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
CMS3_k127_1904685_41	1282360.ABAC460_17450	2.954e-10	67.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,2U17C@28211|Alphaproteobacteria,2KFCB@204458|Caulobacterales	204458|Caulobacterales	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
CMS3_k127_1904685_0	290397.Adeh_0476	6.962e-272	861.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,2YTV0@29|Myxococcales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
CMS3_k127_1904685_31	290397.Adeh_0475	1.123e-34	134.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653,ko:K04654	-	-	-	-	ko00000	-	-	-	HupF_HypC
CMS3_k127_1904685_6	290397.Adeh_0474	4.965e-157	506.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2YTV5@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
CMS3_k127_1904685_10	290397.Adeh_0473	2.217e-140	454.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2WJ8B@28221|Deltaproteobacteria,2YTZM@29|Myxococcales	28221|Deltaproteobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
CMS3_k127_1904685_30	1382304.JNIL01000001_gene2953	2.725e-38	162.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,279HF@186823|Alicyclobacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_1904685_33	404589.Anae109_0514	3.654e-27	126.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
CMS3_k127_1904685_17	404589.Anae109_0513	1.804e-99	334.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KO	TIGRFAM Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
CMS3_k127_1904685_34	583355.Caka_1888	2.959e-26	116.0	COG2836@1|root,COG2836@2|Bacteria,46YGR@74201|Verrucomicrobia,3K9JC@414999|Opitutae	414999|Opitutae	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS3_k127_1904685_14	502025.Hoch_5984	8.12e-114	374.0	COG0501@1|root,COG0501@2|Bacteria,1NG7Y@1224|Proteobacteria,434VJ@68525|delta/epsilon subdivisions,2X91I@28221|Deltaproteobacteria,2Z1FS@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_1904685_23	880073.Calab_1130	3.783e-66	238.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
CMS3_k127_1904685_25	671143.DAMO_2593	3.132e-52	202.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2NS4N@2323|unclassified Bacteria	2|Bacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	2.7.13.3	ko:K03407,ko:K07678,ko:K18143	ko01501,ko02020,ko02025,ko02026,ko02030,ko05111,map01501,map02020,map02025,map02026,map02030,map05111	M00475,M00506,M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022,ko02035	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
CMS3_k127_1904685_37	1267533.KB906733_gene2988	3.141e-19	91.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1904685_3	448385.sce5487	3.736e-208	662.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_1904685_11	1192034.CAP_0672	4.611e-137	467.0	COG0613@1|root,COG0613@2|Bacteria,1R4N5@1224|Proteobacteria	1224|Proteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1904685_43	350058.Mvan_0816	3.175e-08	67.0	COG4402@1|root,COG4402@2|Bacteria,2I90K@201174|Actinobacteria,236XA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_1904685_20	1356852.N008_09465	5.202e-85	291.0	COG5285@1|root,COG5285@2|Bacteria,4NEHK@976|Bacteroidetes,47KVZ@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_1904685_2	502025.Hoch_3972	3.689e-230	735.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2YUN3@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_1904685_35	318424.EU78_11870	2.974e-23	115.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,2399T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_1904685_19	477974.Daud_0268	1.188e-86	308.0	COG0438@1|root,COG2105@1|root,COG0438@2|Bacteria,COG2105@2|Bacteria,1UVR9@1239|Firmicutes,25KKW@186801|Clostridia,265WT@186807|Peptococcaceae	186801|Clostridia	M	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS3_k127_1904685_15	886293.Sinac_3058	2.755e-112	379.0	COG1249@1|root,COG1249@2|Bacteria,2IY39@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_1904685_26	483219.LILAB_06945	2.097e-49	190.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_1904685_27	378806.STAUR_4532	2.113e-48	176.0	COG0741@1|root,COG3023@1|root,COG0741@2|Bacteria,COG3023@2|Bacteria,1N4IN@1224|Proteobacteria,434CV@68525|delta/epsilon subdivisions,2X346@28221|Deltaproteobacteria,2YU5Z@29|Myxococcales	28221|Deltaproteobacteria	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS3_k127_1916559_7	502025.Hoch_4814	2.068e-44	166.0	2AGXG@1|root,31760@2|Bacteria,1PYEX@1224|Proteobacteria,43E45@68525|delta/epsilon subdivisions,2WZNK@28221|Deltaproteobacteria,2Z2FD@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1916559_3	502025.Hoch_4815	1.533e-191	613.0	COG0714@1|root,COG0714@2|Bacteria,1QA7C@1224|Proteobacteria,4342N@68525|delta/epsilon subdivisions,2X4WR@28221|Deltaproteobacteria,2YZRP@29|Myxococcales	28221|Deltaproteobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_5
CMS3_k127_1916559_8	502025.Hoch_4816	3.292e-26	124.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019,GerE,Response_reg
CMS3_k127_1916559_1	502025.Hoch_4817	3.093e-214	675.0	COG2425@1|root,COG2425@2|Bacteria,1Q5ER@1224|Proteobacteria,4341B@68525|delta/epsilon subdivisions,2X4M9@28221|Deltaproteobacteria,2YZ8P@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1916559_0	502025.Hoch_5858	7.001e-249	786.0	COG1413@1|root,COG1413@2|Bacteria,1Q38Z@1224|Proteobacteria,43903@68525|delta/epsilon subdivisions,2X455@28221|Deltaproteobacteria,2YYA6@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_1916559_6	448385.sce8427	8.81e-60	224.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42RQT@68525|delta/epsilon subdivisions,2WW12@28221|Deltaproteobacteria,2Z2WY@29|Myxococcales	28221|Deltaproteobacteria	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,SpoIIE
CMS3_k127_1916559_2	502025.Hoch_5095	5.586e-192	623.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2Z1AZ@29|Myxococcales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS3_k127_1916559_4	502025.Hoch_5096	1.058e-182	582.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,42NWZ@68525|delta/epsilon subdivisions,2WJU7@28221|Deltaproteobacteria,2YYQ1@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS3_k127_1916559_5	96561.Dole_2193	1.902e-64	230.0	COG0451@1|root,COG0451@2|Bacteria,1PE5Z@1224|Proteobacteria,43A0H@68525|delta/epsilon subdivisions,2X262@28221|Deltaproteobacteria,2MN1V@213118|Desulfobacterales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_1939133_3	102232.GLO73106DRAFT_00026080	5.354e-06	60.0	COG1404@1|root,COG2931@1|root,COG3591@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3591@2|Bacteria,1GAB9@1117|Cyanobacteria	1117|Cyanobacteria	O	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
CMS3_k127_1939133_2	502025.Hoch_6539	1.933e-18	93.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1939133_0	448385.sce8649	3.96e-155	544.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_1939133_1	502025.Hoch_4043	4.943e-96	321.0	COG4850@1|root,COG4850@2|Bacteria,1NYAE@1224|Proteobacteria,430HM@68525|delta/epsilon subdivisions,2WW1X@28221|Deltaproteobacteria,2YUT1@29|Myxococcales	28221|Deltaproteobacteria	S	conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1939936_1	404589.Anae109_0988	3.467e-93	322.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42P67@68525|delta/epsilon subdivisions,2WJP7@28221|Deltaproteobacteria,2Z34G@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_1939936_0	1254432.SCE1572_26440	4.246e-114	404.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1,Peptidase_MA_2
CMS3_k127_1939936_2	502025.Hoch_5509	4.181e-75	267.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,43C0B@68525|delta/epsilon subdivisions,2X7B2@28221|Deltaproteobacteria,2Z3EU@29|Myxococcales	28221|Deltaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS3_k127_1945226_8	502025.Hoch_5842	9.381e-20	92.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2YV51@29|Myxococcales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS3_k127_1945226_0	502025.Hoch_5841	0.0	1047.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2YUFJ@29|Myxococcales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS3_k127_1945226_9	502025.Hoch_3501	4.198e-11	72.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_1945226_3	502025.Hoch_5860	9.424e-75	272.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_5860|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1945226_6	502025.Hoch_5861	1.733e-41	166.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	bchC	-	1.1.1.396	ko:K11337	ko00860,ko01110,map00860,map01110	-	R09055	RC01377	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1945226_7	502025.Hoch_5863	3.37e-22	105.0	COG0126@1|root,COG0126@2|Bacteria	2|Bacteria	F	phosphoglycerate kinase activity	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS3_k127_1945226_4	502025.Hoch_5864	1.575e-67	235.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS3_k127_1945226_1	502025.Hoch_5865	7.514e-113	380.0	2A4SV@1|root,30TE9@2|Bacteria,1PD77@1224|Proteobacteria,435ER@68525|delta/epsilon subdivisions,2WZSB@28221|Deltaproteobacteria,2Z2N4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1945226_5	502025.Hoch_5866	1.274e-44	165.0	2BR3K@1|root,32K1I@2|Bacteria,1Q2KA@1224|Proteobacteria,43872@68525|delta/epsilon subdivisions,2X3GX@28221|Deltaproteobacteria,2YW1T@29|Myxococcales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_1945226_2	1192034.CAP_0058	5.244e-89	303.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_1946379_1	246197.MXAN_4745	3.922e-275	856.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS3_k127_1946379_0	649638.Trad_0897	3.14e-296	934.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS3_k127_1946379_2	246197.MXAN_6036	4.255e-109	396.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_1946379_4	1254432.SCE1572_26570	8.617e-49	192.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2X2U1@28221|Deltaproteobacteria,2YWRC@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1946379_7	502025.Hoch_4559	1.116e-35	137.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,437HJ@68525|delta/epsilon subdivisions,2WSUJ@28221|Deltaproteobacteria,2YW0Q@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS3_k127_1946379_9	502025.Hoch_4558	2.483e-21	94.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,4386Y@68525|delta/epsilon subdivisions,2X3GU@28221|Deltaproteobacteria,2YW1F@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS3_k127_1946379_3	1120963.KB894501_gene279	6.89e-95	324.0	COG0657@1|root,COG0657@2|Bacteria,1MVRE@1224|Proteobacteria,1S0ZD@1236|Gammaproteobacteria,2Q58D@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	Pectinacetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	PAE
CMS3_k127_1946379_6	118168.MC7420_2616	9.225e-42	156.0	2DZNU@1|root,32VEW@2|Bacteria,1G855@1117|Cyanobacteria	1117|Cyanobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_1946379_5	1027273.GZ77_17875	1.382e-48	190.0	COG1553@1|root,COG1553@2|Bacteria,1NUU5@1224|Proteobacteria,1SNGR@1236|Gammaproteobacteria,1XPSW@135619|Oceanospirillales	135619|Oceanospirillales	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_1946379_8	118168.MC7420_2659	3.18e-25	109.0	COG1553@1|root,COG1553@2|Bacteria,1GEH9@1117|Cyanobacteria	1117|Cyanobacteria	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_1950553_6	502025.Hoch_5061	5.794e-65	250.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YUF2@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	prlC	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
CMS3_k127_1950553_12	2002.JOEQ01000005_gene3505	1.647e-22	105.0	COG1309@1|root,COG1309@2|Bacteria,2I16R@201174|Actinobacteria,4EM5K@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1950553_10	1144275.COCOR_05771	2.184e-36	150.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,42SXS@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Fic/DOC family	Z012_01130	-	-	-	-	-	-	-	-	-	-	-	DUF977,Fic,HTH_11,HTH_DeoR
CMS3_k127_1950553_0	448385.sce3575	6.049e-253	794.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2YU4C@29|Myxococcales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	ko:K09456,ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS3_k127_1950553_4	502025.Hoch_5059	3.912e-85	291.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,42QH3@68525|delta/epsilon subdivisions,2WKXH@28221|Deltaproteobacteria,2YYMV@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_1950553_8	502025.Hoch_5058	1.581e-45	184.0	COG3794@1|root,COG3794@2|Bacteria,1Q2EH@1224|Proteobacteria,43807@68525|delta/epsilon subdivisions,2X3A8@28221|Deltaproteobacteria,2YV38@29|Myxococcales	28221|Deltaproteobacteria	C	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1950553_3	290397.Adeh_2216	1.271e-86	319.0	2DBW6@1|root,2ZBEP@2|Bacteria,1QUH5@1224|Proteobacteria,43CCA@68525|delta/epsilon subdivisions,2X7N7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM decaheme c-type cytochrome, OmcA MtrC family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1950553_9	502025.Hoch_2084	1.262e-39	158.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	ko:K05385	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
CMS3_k127_1950553_5	502025.Hoch_0084	1.766e-77	265.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2YVUS@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_1950553_11	215803.DB30_2043	1.222e-29	134.0	2B14Q@1|root,31TIJ@2|Bacteria,1QR97@1224|Proteobacteria,435JE@68525|delta/epsilon subdivisions,2WZXH@28221|Deltaproteobacteria,2Z0YB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1950553_1	502025.Hoch_0085	1.1e-199	647.0	COG0492@1|root,COG1146@1|root,COG3266@1|root,COG0492@2|Bacteria,COG1146@2|Bacteria,COG3266@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
CMS3_k127_1950553_7	207954.MED92_05988	4.402e-46	171.0	COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,1S62S@1236|Gammaproteobacteria,1XK30@135619|Oceanospirillales	135619|Oceanospirillales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1950553_13	1282876.BAOK01000002_gene502	7.226e-16	90.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_1950553_2	502025.Hoch_5313	4.207e-120	394.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2YTZQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS3_k127_1952092_24	1254432.SCE1572_34225	3.054e-11	75.0	COG2374@1|root,COG2374@2|Bacteria,1PC28@1224|Proteobacteria,4387J@68525|delta/epsilon subdivisions,2XA0Z@28221|Deltaproteobacteria,2YW3U@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1952092_6	1144275.COCOR_05383	1.405e-140	466.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YY8A@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CMS3_k127_1952092_7	367299.JOEE01000005_gene3518	3.796e-140	459.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4FEJM@85021|Intrasporangiaceae	201174|Actinobacteria	G	Catalyzes the formation of phosphoenolpyruvate from pyruvate	pyk	GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS3_k127_1952092_13	502025.Hoch_4926	1.055e-76	263.0	COG1266@1|root,COG1266@2|Bacteria,1RI59@1224|Proteobacteria,433F0@68525|delta/epsilon subdivisions,2WYHI@28221|Deltaproteobacteria,2Z276@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_1952092_3	502025.Hoch_4925	4.277e-189	605.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2YTWF@29|Myxococcales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
CMS3_k127_1952092_19	404380.Gbem_2739	4.866e-25	105.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_1952092_22	502025.Hoch_5246	1.734e-16	87.0	COG0810@1|root,COG0810@2|Bacteria,1QGPT@1224|Proteobacteria,434QY@68525|delta/epsilon subdivisions,2WZ24@28221|Deltaproteobacteria,2Z15Z@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1952092_9	502025.Hoch_5246	2.267e-113	387.0	COG0810@1|root,COG0810@2|Bacteria,1QGPT@1224|Proteobacteria,434QY@68525|delta/epsilon subdivisions,2WZ24@28221|Deltaproteobacteria,2Z15Z@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1952092_14	67267.JNXT01000038_gene3373	2.548e-67	254.0	2BWNB@1|root,32WFI@2|Bacteria,2IAXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1952092_8	926550.CLDAP_27080	1.616e-123	407.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	2|Bacteria	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	patA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K05830,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R01155,R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426	Aminotran_3
CMS3_k127_1952092_11	502025.Hoch_2446	2.29e-91	305.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS3_k127_1952092_4	502025.Hoch_2444	2.362e-180	592.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2YVGD@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS3_k127_1952092_2	502025.Hoch_6394	2.553e-190	637.0	COG2010@1|root,COG2010@2|Bacteria,1R03D@1224|Proteobacteria,43CQJ@68525|delta/epsilon subdivisions,2X7Y0@28221|Deltaproteobacteria,2Z1XC@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_1952092_18	1089550.ATTH01000001_gene1572	1.209e-40	160.0	COG2267@1|root,COG2267@2|Bacteria,4NK80@976|Bacteroidetes	976|Bacteroidetes	I	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_1952092_16	404589.Anae109_3838	2.599e-54	208.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,43AFC@68525|delta/epsilon subdivisions,2X64J@28221|Deltaproteobacteria,2Z0UN@29|Myxococcales	28221|Deltaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_1952092_1	502025.Hoch_3436	8.448e-195	619.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUE5@29|Myxococcales	28221|Deltaproteobacteria	D	HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
CMS3_k127_1952092_12	1242864.D187_008554	6.61e-90	304.0	COG0035@1|root,COG0035@2|Bacteria,1RBD6@1224|Proteobacteria,42R1E@68525|delta/epsilon subdivisions,2WN3Q@28221|Deltaproteobacteria,2YU4E@29|Myxococcales	28221|Deltaproteobacteria	F	Uracil phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UPRTase
CMS3_k127_1952092_15	502025.Hoch_3435	2.895e-65	240.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2YV3U@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS3_k127_1952092_17	1121422.AUMW01000019_gene1815	4.162e-45	176.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1UI8N@1239|Firmicutes,25EE0@186801|Clostridia,260HY@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
CMS3_k127_1952092_25	378806.STAUR_5838	2.817e-08	67.0	2AJ0N@1|root,319IP@2|Bacteria,1Q2W6@1224|Proteobacteria,438IW@68525|delta/epsilon subdivisions,2X3TT@28221|Deltaproteobacteria,2YX38@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1952092_10	502025.Hoch_3432	4.009e-112	371.0	COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K02657,ko:K20972	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035,ko02044	-	-	-	HATPase_c,HisKA,Hpt,Response_reg
CMS3_k127_1952092_26	215803.DB30_6047	6.496e-07	60.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,2YYW2@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS3_k127_1952092_5	391625.PPSIR1_24094	2.816e-150	484.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_1952092_0	502025.Hoch_1946	0.0	1212.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2YU3X@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_1952092_20	404589.Anae109_1523	3.964e-23	115.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70,PilZ
CMS3_k127_1956083_0	1144275.COCOR_03350	4.468e-62	232.0	COG4254@1|root,COG4254@2|Bacteria,1QVB5@1224|Proteobacteria,42XP1@68525|delta/epsilon subdivisions,2X71D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS3_k127_1956083_4	1144275.COCOR_03351	5.69e-09	68.0	COG0515@1|root,COG0515@2|Bacteria	1144275.COCOR_03351|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_1956083_1	502025.Hoch_1684	8.088e-41	166.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,DUF4215,RCC1_2,TIG
CMS3_k127_1961261_0	502025.Hoch_5549	3.962e-298	938.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2YU5P@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS3_k127_1961261_2	1048339.KB913029_gene3877	3.826e-82	284.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria,4ERND@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
CMS3_k127_1961261_1	502025.Hoch_5550	7.888e-105	360.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria,2YWZP@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_1961261_4	483219.LILAB_19940	1.35e-65	237.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2WJIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
CMS3_k127_1961261_7	1278073.MYSTI_02840	1.593e-40	160.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,42NX7@68525|delta/epsilon subdivisions,2WNFE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar biosynthetic protein FliR	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
CMS3_k127_1961261_9	246197.MXAN_2448	3.774e-16	90.0	COG1987@1|root,COG1987@2|Bacteria,1R357@1224|Proteobacteria,42XBY@68525|delta/epsilon subdivisions,2WR4T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
CMS3_k127_1961261_3	215803.DB30_3692	4.337e-72	253.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,43DJ1@68525|delta/epsilon subdivisions,2X8QB@28221|Deltaproteobacteria,2YVQS@29|Myxococcales	28221|Deltaproteobacteria	NU	FliP family	-	-	-	ko:K03226	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	FliP
CMS3_k127_1961261_10	644282.Deba_2314	3.355e-05	52.0	COG3190@1|root,COG3190@2|Bacteria	2|Bacteria	N	flagellar	fliP	-	-	ko:K02418,ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO,FliP
CMS3_k127_1961261_5	1209989.TepiRe1_1809	2e-65	241.0	COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,2494Y@186801|Clostridia,42FDX@68295|Thermoanaerobacterales	186801|Clostridia	S	pfam abc1	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CMS3_k127_1961261_8	391625.PPSIR1_42054	6.397e-31	138.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Exo_endo_phos,HemolysinCabind,LTD
CMS3_k127_1961261_6	502025.Hoch_3978	5.596e-47	176.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2Z32V@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS3_k127_1970760_3	671143.DAMO_1172	1.033e-07	61.0	COG1715@1|root,COG1715@2|Bacteria	2|Bacteria	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
CMS3_k127_1970760_1	502025.Hoch_6777	5.496e-102	338.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS3_k127_1970760_2	5127.CCT67725	1.066e-78	284.0	COG1087@1|root,KOG1371@2759|Eukaryota,39KCQ@33154|Opisthokonta,3PBHS@4751|Fungi,3RN10@4890|Ascomycota,21D2X@147550|Sordariomycetes,3TKEP@5125|Hypocreales,1FVEQ@110618|Nectriaceae	4751|Fungi	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
CMS3_k127_1970760_0	502025.Hoch_6075	4.192e-157	506.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2YTZC@29|Myxococcales	28221|Deltaproteobacteria	C	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_1975643_11	502025.Hoch_1839	2.882e-17	81.0	COG0457@1|root,COG0457@2|Bacteria,1QQ0R@1224|Proteobacteria,433U8@68525|delta/epsilon subdivisions,2X3GZ@28221|Deltaproteobacteria,2YW20@29|Myxococcales	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,zinc_ribbon_4
CMS3_k127_1975643_5	1051632.TPY_3224	1.798e-88	321.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248IC@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 31	yicI	-	3.2.1.177,3.2.1.199	ko:K01811,ko:K15922	-	-	R00802,R11543	RC00028,RC00059,RC00077,RC00451	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
CMS3_k127_1975643_10	502025.Hoch_4086	1.383e-41	158.0	COG0664@1|root,COG0664@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2YVYQ@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
CMS3_k127_1975643_9	502025.Hoch_0300	6.411e-51	202.0	2CI35@1|root,32SUG@2|Bacteria,1PZ8E@1224|Proteobacteria,43E6E@68525|delta/epsilon subdivisions,2WZV6@28221|Deltaproteobacteria,2Z2TN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1975643_7	502025.Hoch_0299	3.34e-79	291.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2Z31A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS3_k127_1975643_2	502025.Hoch_0298	2.51e-103	363.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YUS3@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1975643_3	502025.Hoch_0297	7.824e-100	345.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_1975643_1	502025.Hoch_0296	1.518e-160	510.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,2YU9G@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_1975643_6	502025.Hoch_5997	8.216e-86	310.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2YVEB@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
CMS3_k127_1975643_8	502025.Hoch_6570	5.361e-64	244.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1NM9N@1224|Proteobacteria,42PSP@68525|delta/epsilon subdivisions,2WQ97@28221|Deltaproteobacteria,2YXR7@29|Myxococcales	28221|Deltaproteobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
CMS3_k127_1975643_4	502025.Hoch_4089	2.093e-89	301.0	COG1657@1|root,COG1657@2|Bacteria,1QX5U@1224|Proteobacteria,42ZX1@68525|delta/epsilon subdivisions,2WVF4@28221|Deltaproteobacteria,2YV56@29|Myxococcales	28221|Deltaproteobacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CMS3_k127_1975643_0	502025.Hoch_4088	4.919e-275	865.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
CMS3_k127_197701_4	502025.Hoch_1808	3.438e-25	111.0	COG0848@1|root,COG0848@2|Bacteria,1QAS7@1224|Proteobacteria,43E3G@68525|delta/epsilon subdivisions,2WZKU@28221|Deltaproteobacteria,2Z2C1@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_197701_7	78245.Xaut_3783	0.0005736	49.0	2DZ9M@1|root,32V6Z@2|Bacteria,1R7AU@1224|Proteobacteria,2TUDM@28211|Alphaproteobacteria,3F1Y2@335928|Xanthobacteraceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_197701_6	215803.DB30_7093	7.101e-16	92.0	2BR1I@1|root,32JZ2@2|Bacteria,1Q2J5@1224|Proteobacteria,43863@68525|delta/epsilon subdivisions,2X3FX@28221|Deltaproteobacteria,2YVXD@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_197701_2	246197.MXAN_5587	3.663e-73	263.0	2AK94@1|root,31AZD@2|Bacteria,1Q6KJ@1224|Proteobacteria,439D5@68525|delta/epsilon subdivisions,2X4MU@28221|Deltaproteobacteria,2YZ9M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_197701_3	1242864.D187_006963	1.156e-71	254.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,439T1@68525|delta/epsilon subdivisions,2X563@28221|Deltaproteobacteria,2Z05Z@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
CMS3_k127_197701_0	391625.PPSIR1_37274	2.492e-158	515.0	COG1649@1|root,COG1649@2|Bacteria,1N99Y@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	yddW	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS3_k127_197701_1	502025.Hoch_5570	3.798e-98	331.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,42W62@68525|delta/epsilon subdivisions,2X67E@28221|Deltaproteobacteria,2YVZM@29|Myxococcales	28221|Deltaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS3_k127_197701_8	762903.Pedsa_3104	0.0006818	51.0	COG1874@1|root,COG1874@2|Bacteria,4NNXU@976|Bacteroidetes,1IZR4@117747|Sphingobacteriia	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
CMS3_k127_1978671_6	84531.JMTZ01000168_gene725	4.211e-11	70.0	290G0@1|root,2ZN55@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1978671_9	1380386.JIAW01000001_gene4692	0.0009906	45.0	COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,23B3M@1762|Mycobacteriaceae	201174|Actinobacteria	S	AraC-like ligand binding domain	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD,Cupin_2
CMS3_k127_1978671_7	1121441.AUCX01000008_gene2199	2.248e-08	56.0	COG4319@1|root,COG4319@2|Bacteria,1RDC2@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	yybH	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
CMS3_k127_1978671_0	1123261.AXDW01000007_gene2185	8.779e-192	617.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQD3@1236|Gammaproteobacteria,1X5A8@135614|Xanthomonadales	135614|Xanthomonadales	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_1978671_1	344747.PM8797T_14594	1.311e-119	404.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_1978671_3	1254432.SCE1572_32740	7.72e-58	211.0	COG0625@1|root,COG3631@1|root,COG0625@2|Bacteria,COG3631@2|Bacteria,1N3UG@1224|Proteobacteria	1224|Proteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CMS3_k127_1978671_2	1449346.JQMO01000003_gene2423	9.8e-81	305.0	COG3899@1|root,COG3899@2|Bacteria,2HEUH@201174|Actinobacteria,2M5KT@2063|Kitasatospora	201174|Actinobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
CMS3_k127_1978671_5	948106.AWZT01000058_gene556	5.766e-13	71.0	2C1W2@1|root,30WYT@2|Bacteria,1PIQW@1224|Proteobacteria,2W7AG@28216|Betaproteobacteria,1KE75@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_1978671_4	272134.KB731324_gene4252	6.247e-55	212.0	COG3629@1|root,COG3629@2|Bacteria,1G5W7@1117|Cyanobacteria,1HEAR@1150|Oscillatoriales	1117|Cyanobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS3_k127_198786_1	391625.PPSIR1_04263	2.167e-29	122.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Lectin_C,Polyketide_cyc2,VPEP,VWA_2,VWA_3
CMS3_k127_198786_0	1144275.COCOR_03694	7.178e-153	493.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42ZB2@68525|delta/epsilon subdivisions,2WUMC@28221|Deltaproteobacteria,2YUFT@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS3_k127_1995458_0	502025.Hoch_4653	9.629e-254	788.0	COG2719@1|root,COG2719@2|Bacteria,1MW6U@1224|Proteobacteria,42MYY@68525|delta/epsilon subdivisions,2WJ6V@28221|Deltaproteobacteria,2YUGF@29|Myxococcales	28221|Deltaproteobacteria	S	SpoVR like protein	spoVR	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
CMS3_k127_1995458_1	502025.Hoch_4652	1.635e-86	299.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria,2YV2K@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_1995458_6	658612.MD26_00605	0.0002592	53.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
CMS3_k127_1995458_5	1996.JOFO01000028_gene5962	2.904e-15	88.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4EK02@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1995458_4	1123392.AQWL01000013_gene2383	1.038e-15	89.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	rmpM	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,SmpA_OmlA
CMS3_k127_1995458_2	502025.Hoch_4651	1.222e-59	222.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K16191,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6.1.3	-	-	BON,Gram_pos_anchor,OmpA,TSP_3
CMS3_k127_2004010_8	34007.IT40_24760	0.0002839	44.0	COG2044@1|root,COG2044@2|Bacteria,1RIFN@1224|Proteobacteria,2UBMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_2004010_2	1123024.AUII01000052_gene3914	4.009e-56	213.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_2004010_6	1089455.MOPEL_020_00340	1.413e-08	68.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4F664@85018|Dermatophilaceae	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_2004010_5	1048339.KB913029_gene4685	6.553e-10	71.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	GGDEF,HTH_Crp_2,cNMP_binding
CMS3_k127_2004010_7	935839.JAGJ01000010_gene310	1.728e-05	57.0	COG2234@1|root,COG3509@1|root,COG2234@2|Bacteria,COG3509@2|Bacteria,2I0Q0@201174|Actinobacteria,4F57Q@85017|Promicromonosporaceae	201174|Actinobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
CMS3_k127_2004010_1	448385.sce8429	1.359e-74	262.0	COG0265@1|root,COG0515@1|root,COG3287@1|root,COG0265@2|Bacteria,COG0515@2|Bacteria,COG3287@2|Bacteria,1PEIZ@1224|Proteobacteria,433VS@68525|delta/epsilon subdivisions,2X3Q2@28221|Deltaproteobacteria,2YWTJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PDZ_2,Pkinase
CMS3_k127_2004010_3	1203605.HMPREF1531_00749	5.626e-53	206.0	COG4816@1|root,COG4816@2|Bacteria,2H39Q@201174|Actinobacteria,4DT6Q@85009|Propionibacteriales	201174|Actinobacteria	E	BMC	-	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
CMS3_k127_2004010_4	1089553.Tph_c06950	3.65e-42	177.0	COG4302@1|root,COG4302@2|Bacteria,1TSZM@1239|Firmicutes,24A5Y@186801|Clostridia	186801|Clostridia	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
CMS3_k127_2004010_0	1121289.JHVL01000006_gene2849	7.97e-168	538.0	COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,248P5@186801|Clostridia,36FF6@31979|Clostridiaceae	186801|Clostridia	E	PFAM Ethanolamine ammonia lyase large subunit	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
CMS3_k127_2011836_2	502025.Hoch_4475	4.986e-65	228.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria,2YU3Q@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_2011836_0	502025.Hoch_4476	0.0	1204.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2YUDT@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS3_k127_2011836_1	502025.Hoch_4477	1.884e-288	900.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2YTWV@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_2011836_3	1157637.KB892102_gene1523	4.19e-08	63.0	COG2267@1|root,COG2267@2|Bacteria,2GMBV@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_2012000_5	278963.ATWD01000002_gene393	1.316e-07	53.0	COG1881@1|root,COG1881@2|Bacteria	2|Bacteria	S	positive regulation of acetylcholine metabolic process	bbsI	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS3_k127_2012000_4	1278309.KB907105_gene1507	4.108e-14	77.0	2DN81@1|root,32W0Z@2|Bacteria,1MZF2@1224|Proteobacteria,1S9F7@1236|Gammaproteobacteria,1XKU8@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2012000_0	502025.Hoch_5968	6.226e-208	680.0	COG2960@1|root,COG2960@2|Bacteria,1Q3HW@1224|Proteobacteria,439AW@68525|delta/epsilon subdivisions,2X4IK@28221|Deltaproteobacteria,2YZ3D@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_2012000_1	502025.Hoch_5967	6.454e-180	589.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,437W2@68525|delta/epsilon subdivisions,2X35K@28221|Deltaproteobacteria,2YXG5@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_2012000_2	502025.Hoch_0549	2.187e-93	318.0	COG0467@1|root,COG0467@2|Bacteria,1RFBT@1224|Proteobacteria,42QWP@68525|delta/epsilon subdivisions,2WMB2@28221|Deltaproteobacteria,2YTTP@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2012000_3	448385.sce0644	2.62e-46	169.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42NDG@68525|delta/epsilon subdivisions,2WKYU@28221|Deltaproteobacteria,2YTWT@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_2020801_2	1301098.PKB_4237	1.973e-104	342.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	mhpE	-	2.3.3.13,4.1.3.39,4.1.3.43	ko:K01649,ko:K01666,ko:K18365	ko00290,ko00360,ko00362,ko00620,ko00621,ko00622,ko01100,ko01110,ko01120,ko01210,ko01220,ko01230,map00290,map00360,map00362,map00620,map00621,map00622,map01100,map01110,map01120,map01210,map01220,map01230	M00432,M00545,M00569	R00750,R01213,R05298	RC00004,RC00307,RC00371,RC00470,RC00572,RC02754	br01601,br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
CMS3_k127_2020801_0	402881.Plav_2205	1.388e-155	499.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_22780	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2020801_1	1278073.MYSTI_04831	1.401e-113	387.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria,2YYYG@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2020801_3	1173026.Glo7428_4741	3.535e-31	135.0	COG1357@1|root,COG1357@2|Bacteria,1G1UU@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_20237_2	215803.DB30_0799	4.632e-32	143.0	COG4257@1|root,COG4257@2|Bacteria,1QX4A@1224|Proteobacteria,43BWT@68525|delta/epsilon subdivisions,2X4K2@28221|Deltaproteobacteria,2YZ67@29|Myxococcales	28221|Deltaproteobacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,HYR
CMS3_k127_20237_4	1192034.CAP_2122	7.878e-07	62.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
CMS3_k127_20237_3	502025.Hoch_5410	1.497e-17	90.0	COG1981@1|root,COG1981@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS3_k127_20237_0	502025.Hoch_5890	1.682e-149	482.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS3_k127_20237_1	1000565.METUNv1_00106	1.144e-32	129.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2VSQ1@28216|Betaproteobacteria,2KWPM@206389|Rhodocyclales	206389|Rhodocyclales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_2025784_2	96561.Dole_0484	1.437e-66	242.0	COG1331@1|root,COG1331@2|Bacteria,1PE5T@1224|Proteobacteria,43F3F@68525|delta/epsilon subdivisions,2WZ7I@28221|Deltaproteobacteria,2MP4B@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2025784_12	1034769.KB910518_gene747	3.71e-11	69.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,26X94@186822|Paenibacillaceae	91061|Bacilli	L	DNA uptake protein and related DNA-binding proteins	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS3_k127_2025784_1	502025.Hoch_1843	1.087e-119	411.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,42V1G@68525|delta/epsilon subdivisions,2WRCZ@28221|Deltaproteobacteria,2YWCA@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2025784_7	1089547.KB913013_gene1373	1.374e-36	147.0	COG4430@1|root,COG4430@2|Bacteria,4NN4Z@976|Bacteroidetes,47PX0@768503|Cytophagia	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
CMS3_k127_2025784_8	1415780.JPOG01000001_gene2196	2.687e-35	147.0	COG3714@1|root,COG3714@2|Bacteria,1QE44@1224|Proteobacteria,1TAFY@1236|Gammaproteobacteria,1X8EB@135614|Xanthomonadales	135614|Xanthomonadales	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
CMS3_k127_2025784_10	235985.BBPN01000012_gene6857	1.978e-21	98.0	COG3467@1|root,COG3467@2|Bacteria,2I2V6@201174|Actinobacteria,2NIY9@228398|Streptacidiphilus	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_2025784_3	448385.sce1237	2.782e-55	220.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria	1224|Proteobacteria	G	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
CMS3_k127_2025784_11	1173023.KE650771_gene527	2.227e-18	98.0	2AQRE@1|root,31FZ6@2|Bacteria,1G7D6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2025784_9	1120999.JONM01000002_gene908	3.085e-28	121.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2VS8Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS3_k127_2025784_6	1041138.KB890225_gene6199	4.144e-37	149.0	COG0346@1|root,COG0346@2|Bacteria,1RI45@1224|Proteobacteria,2VEQT@28211|Alphaproteobacteria,4BFVQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2025784_5	65497.JODV01000004_gene1451	3.029e-44	169.0	COG3324@1|root,COG3324@2|Bacteria,2IM88@201174|Actinobacteria,4EAPN@85010|Pseudonocardiales	201174|Actinobacteria	EGP	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_2025784_13	13035.Dacsa_3296	1.009e-09	71.0	COG0221@1|root,COG0221@2|Bacteria,1G1Q3@1117|Cyanobacteria	1117|Cyanobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS3_k127_2025784_0	391625.PPSIR1_34168	0.0	1129.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2WM7X@28221|Deltaproteobacteria,2YUEI@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
CMS3_k127_2025784_4	1254432.SCE1572_13585	7.206e-51	187.0	COG2133@1|root,COG2133@2|Bacteria,1PEHH@1224|Proteobacteria,437W5@68525|delta/epsilon subdivisions,2X35P@28221|Deltaproteobacteria,2YUDG@29|Myxococcales	28221|Deltaproteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_2034513_1	502025.Hoch_3552	1.456e-255	826.0	2AIZE@1|root,319HE@2|Bacteria,1Q2SG@1224|Proteobacteria,438E3@68525|delta/epsilon subdivisions,2X3P8@28221|Deltaproteobacteria,2YWR0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2034513_2	448385.sce9161	1.184e-221	733.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2034513_5	502025.Hoch_3603	1.358e-94	322.0	COG0500@1|root,COG2226@2|Bacteria,1QAUX@1224|Proteobacteria,43DSB@68525|delta/epsilon subdivisions,2X8UK@28221|Deltaproteobacteria,2Z0G1@29|Myxococcales	28221|Deltaproteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2034513_10	1242864.D187_010069	7.009e-68	254.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
CMS3_k127_2034513_12	502025.Hoch_3602	5.015e-53	206.0	2BBR2@1|root,32597@2|Bacteria,1QAQN@1224|Proteobacteria,43E36@68525|delta/epsilon subdivisions,2WZJR@28221|Deltaproteobacteria,2Z2A1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2034513_4	502025.Hoch_2385	3.962e-134	441.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,43ASZ@68525|delta/epsilon subdivisions,2X679@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_2034513_6	502025.Hoch_2384	7.357e-87	307.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria,2Z2AR@29|Myxococcales	28221|Deltaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_7,TPR_8
CMS3_k127_2034513_0	502025.Hoch_2382	5.316e-299	924.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_2034513_9	502025.Hoch_2380	3.557e-68	242.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,2Z2XF@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS3_k127_2034513_11	1192034.CAP_1523	7.642e-58	232.0	COG0515@1|root,COG2909@1|root,COG0515@2|Bacteria,COG2909@2|Bacteria,1QA6R@1224|Proteobacteria,4393M@68525|delta/epsilon subdivisions,2X49J@28221|Deltaproteobacteria,2YYJG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2034513_13	502025.Hoch_2377	2.98e-37	153.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N_3
CMS3_k127_2034513_14	502025.Hoch_2376	5.242e-34	146.0	COG2018@1|root,COG2018@2|Bacteria,1P95I@1224|Proteobacteria,432RB@68525|delta/epsilon subdivisions,2WY07@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2034513_8	502025.Hoch_2375	1.229e-75	275.0	2AGZQ@1|root,3178G@2|Bacteria,1PYI9@1224|Proteobacteria,435DD@68525|delta/epsilon subdivisions,2WZQZ@28221|Deltaproteobacteria,2Z2JG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2034513_3	502025.Hoch_2374	2.461e-159	506.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YXCF@29|Myxococcales	28221|Deltaproteobacteria	S	MCM2/3/5 family	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_2038382_2	502025.Hoch_0362	9.764e-125	417.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,4389R@68525|delta/epsilon subdivisions,2XA3N@28221|Deltaproteobacteria,2YWAI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_2038382_4	502025.Hoch_0363	1.951e-21	106.0	COG0457@1|root,COG0457@2|Bacteria,1PXHP@1224|Proteobacteria,434K6@68525|delta/epsilon subdivisions,2WYXE@28221|Deltaproteobacteria,2Z0V1@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16
CMS3_k127_2038382_3	483219.LILAB_27370	1.811e-40	165.0	COG0457@1|root,COG0664@1|root,COG0457@2|Bacteria,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YXD4@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_2038382_0	502025.Hoch_0364	1.269e-135	444.0	COG3509@1|root,COG3509@2|Bacteria,1PI9N@1224|Proteobacteria,439C2@68525|delta/epsilon subdivisions,2X4K6@28221|Deltaproteobacteria,2YVGR@29|Myxococcales	28221|Deltaproteobacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS3_k127_2038382_1	502025.Hoch_0369	1.85e-130	452.0	COG2340@1|root,COG2340@2|Bacteria,1REVB@1224|Proteobacteria,4386P@68525|delta/epsilon subdivisions,2X3GI@28221|Deltaproteobacteria,2YW01@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_2039533_9	502025.Hoch_5548	4.176e-76	280.0	COG0484@1|root,COG0484@2|Bacteria,1QZTP@1224|Proteobacteria,43CNK@68525|delta/epsilon subdivisions,2X7VX@28221|Deltaproteobacteria,2Z3IP@29|Myxococcales	28221|Deltaproteobacteria	K	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2039533_6	502025.Hoch_2582	8.709e-111	368.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,2YUSE@29|Myxococcales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS3_k127_2039533_10	166318.Syn8016DRAFT_2541	1.395e-70	255.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1G1K0@1117|Cyanobacteria,1GYZM@1129|Synechococcus	1117|Cyanobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
CMS3_k127_2039533_8	502025.Hoch_2590	9.297e-90	311.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_2039533_7	502025.Hoch_5158	4.054e-96	317.0	COG1396@1|root,COG2204@1|root,COG1396@2|Bacteria,COG2204@2|Bacteria,1QX91@1224|Proteobacteria,43C22@68525|delta/epsilon subdivisions,2X7CN@28221|Deltaproteobacteria,2YV1B@29|Myxococcales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Response_reg
CMS3_k127_2039533_2	502025.Hoch_5160	2.074e-270	851.0	COG1142@1|root,COG1142@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_7,Fer4_9,Pyr_redox_2,Pyr_redox_3,cNMP_binding
CMS3_k127_2039533_1	502025.Hoch_5161	0.0	1057.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
CMS3_k127_2039533_0	502025.Hoch_3260	0.0	1266.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1N4IM@1224|Proteobacteria,437ZC@68525|delta/epsilon subdivisions,2WZWU@28221|Deltaproteobacteria,2YUXT@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA
CMS3_k127_2039533_3	502025.Hoch_3261	9.651e-233	739.0	COG2304@1|root,COG2304@2|Bacteria,1PYZT@1224|Proteobacteria,435MP@68525|delta/epsilon subdivisions,2XA2Q@28221|Deltaproteobacteria,2YYF8@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_2039533_5	502025.Hoch_3262	1.272e-144	463.0	COG1721@1|root,COG1721@2|Bacteria,1NEAC@1224|Proteobacteria,43B78@68525|delta/epsilon subdivisions,2X6KP@28221|Deltaproteobacteria,2YWA8@29|Myxococcales	28221|Deltaproteobacteria	S	Von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_2039533_4	502025.Hoch_3263	1.207e-161	516.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YYCD@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_2039533_12	502025.Hoch_3264	8.694e-69	243.0	COG1196@1|root,COG1196@2|Bacteria,1Q5CV@1224|Proteobacteria,439J1@68525|delta/epsilon subdivisions,2X4VH@28221|Deltaproteobacteria,2Z08N@29|Myxococcales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2045476_1	94624.Bpet0155	1.434e-35	139.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2VIJB@28216|Betaproteobacteria,3T1YG@506|Alcaligenaceae	28216|Betaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	adhC	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_2045476_2	1254432.SCE1572_32755	2.795e-30	131.0	COG2374@1|root,COG5184@1|root,COG2374@2|Bacteria,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria	1224|Proteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_2045476_0	234267.Acid_4317	1.397e-42	181.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	LVIVD,SBP56
CMS3_k127_2067827_4	378806.STAUR_1405	1.33e-12	81.0	COG3168@1|root,COG3168@2|Bacteria,1RIDD@1224|Proteobacteria,437WV@68525|delta/epsilon subdivisions,2X36H@28221|Deltaproteobacteria,2YUIH@29|Myxococcales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
CMS3_k127_2067827_2	391625.PPSIR1_01512	5.177e-25	121.0	COG4102@1|root,COG4102@2|Bacteria,1Q27J@1224|Proteobacteria,437U5@68525|delta/epsilon subdivisions,2X33S@28221|Deltaproteobacteria,2YU36@29|Myxococcales	391625.PPSIR1_01512|-	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2067827_7	143224.JQMD01000002_gene641	0.0001471	53.0	COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,1HWYF@117743|Flavobacteriia	976|Bacteroidetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CMS3_k127_2067827_6	1123065.ATWL01000004_gene2789	8.017e-05	55.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180,PadR,Vir_act_alpha_C
CMS3_k127_2067827_1	298655.KI912267_gene6941	1.006e-37	156.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS3_k127_2067827_3	448385.sce4032	5.878e-19	99.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_2067827_0	502025.Hoch_3713	1.308e-112	389.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Big_3_2,CARDB,F5_F8_type_C,FlgD_ig,PD40,Prenyltrans
CMS3_k127_2068270_1	402881.Plav_0548	3.502e-82	280.0	COG1028@1|root,COG1028@2|Bacteria,1PFTU@1224|Proteobacteria,2V7R9@28211|Alphaproteobacteria,1JQ79@119043|Rhodobiaceae	402881.Plav_0548|-	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2068270_4	502025.Hoch_1796	1.65e-37	146.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2YYZA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2068270_2	880073.Calab_1130	7.43e-62	229.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
CMS3_k127_2068270_0	324602.Caur_3920	2.756e-159	526.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,3756Y@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS3_k127_2086084_15	395494.Galf_0004	2.055e-53	191.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS3_k127_2086084_5	394221.Mmar10_1979	3.406e-118	394.0	COG3420@1|root,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,2TTFV@28211|Alphaproteobacteria,4414Y@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_2086084_7	761193.Runsl_1134	8.553e-89	320.0	COG5434@1|root,COG5434@2|Bacteria,4NFZJ@976|Bacteroidetes,47K9P@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,fn3
CMS3_k127_2086084_11	448385.sce2470	1.286e-65	258.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
CMS3_k127_2086084_3	1282876.BAOK01000001_gene2050	1.026e-121	406.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,2TSN9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the amidase family	MA20_04710	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_2086084_18	887062.HGR_05216	1.441e-06	60.0	COG0425@1|root,COG0425@2|Bacteria,1R8DP@1224|Proteobacteria,2WFJB@28216|Betaproteobacteria,4AD5S@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_2086084_1	502025.Hoch_3164	1.28e-275	880.0	COG2304@1|root,COG4676@1|root,COG4783@1|root,COG2304@2|Bacteria,COG4676@2|Bacteria,COG4783@2|Bacteria,1PCRX@1224|Proteobacteria,433WB@68525|delta/epsilon subdivisions,2X9AU@28221|Deltaproteobacteria,2YX4K@29|Myxococcales	28221|Deltaproteobacteria	E	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
CMS3_k127_2086084_12	1192034.CAP_5642	8.748e-61	232.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,Pkinase_Tyr,WD40
CMS3_k127_2086084_8	448385.sce2001	1.735e-87	295.0	COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,43AR8@68525|delta/epsilon subdivisions,2X658@28221|Deltaproteobacteria,2Z39A@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_2086084_16	1192034.CAP_0944	3.896e-37	151.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,434U0@68525|delta/epsilon subdivisions,2WZ4Y@28221|Deltaproteobacteria,2Z1C7@29|Myxococcales	28221|Deltaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_2086084_6	1254432.SCE1572_12185	1.906e-106	358.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,42QU2@68525|delta/epsilon subdivisions,2WMSF@28221|Deltaproteobacteria,2YYYW@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2086084_4	448385.sce1997	5.152e-119	395.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YZPZ@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2086084_2	448385.sce1995	1.095e-228	737.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
CMS3_k127_2086084_10	1192034.CAP_0949	5.542e-72	270.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS3_k127_2086084_17	448385.sce3490	4.758e-16	91.0	COG0515@1|root,COG0515@2|Bacteria,1P2EB@1224|Proteobacteria,438NX@68525|delta/epsilon subdivisions,2X8TD@28221|Deltaproteobacteria,2YXD6@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2086084_0	1380394.JADL01000024_gene101	2e-322	1002.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JRCI@204441|Rhodospirillales	204441|Rhodospirillales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
CMS3_k127_2086084_14	665571.STHERM_c17700	1.421e-57	210.0	COG0508@1|root,COG0508@2|Bacteria,2J5U3@203691|Spirochaetes	203691|Spirochaetes	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
CMS3_k127_2086084_9	502025.Hoch_4697	2.913e-86	297.0	COG0515@1|root,COG0515@2|Bacteria,1Q38J@1224|Proteobacteria,438ZJ@68525|delta/epsilon subdivisions,2X44T@28221|Deltaproteobacteria,2YY98@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	masK	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2089730_6	502025.Hoch_3501	3.674e-05	54.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_2089730_4	450851.PHZ_c0887	1.242e-44	172.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2U5IH@28211|Alphaproteobacteria,2KF3Y@204458|Caulobacterales	204458|Caulobacterales	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N_3
CMS3_k127_2089730_3	378806.STAUR_3397	1.198e-51	190.0	COG0494@1|root,COG0494@2|Bacteria,1Q2GD@1224|Proteobacteria,433T7@68525|delta/epsilon subdivisions,2X3CU@28221|Deltaproteobacteria,2YVG9@29|Myxococcales	28221|Deltaproteobacteria	L	nUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_2089730_1	502025.Hoch_2202	3.18e-103	354.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2X5AW@28221|Deltaproteobacteria,2Z34Y@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS3_k127_2089730_0	502025.Hoch_2203	2.152e-182	584.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N16@68525|delta/epsilon subdivisions,2X5GX@28221|Deltaproteobacteria,2YTTV@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_2089730_7	926692.AZYG01000047_gene2610	0.0001046	54.0	COG1388@1|root,COG1388@2|Bacteria,1UJSB@1239|Firmicutes,24MVZ@186801|Clostridia,3WC6G@53433|Halanaerobiales	186801|Clostridia	M	Intracellular proteinase inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI,LysM
CMS3_k127_2089730_2	502025.Hoch_3401	6.305e-103	343.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2YU66@29|Myxococcales	28221|Deltaproteobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS3_k127_2093886_0	391625.PPSIR1_09101	1.485e-182	590.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1QZSZ@1224|Proteobacteria,435V5@68525|delta/epsilon subdivisions,2X0DK@28221|Deltaproteobacteria,2YZ54@29|Myxococcales	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PKD
CMS3_k127_210104_5	7176.CPIJ016596-PA	1.098e-05	48.0	2CY4I@1|root,2S1ZX@2759|Eukaryota,3A4ME@33154|Opisthokonta,3BS4H@33208|Metazoa,3D949@33213|Bilateria,42AYK@6656|Arthropoda,3T0CF@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_210104_1	448385.sce0313	8.933e-66	231.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_210104_2	502025.Hoch_3523	4.117e-37	150.0	COG4233@1|root,COG4233@2|Bacteria,1NF38@1224|Proteobacteria	1224|Proteobacteria	CO	to be involved in C-type cytochrome biogenesis	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC
CMS3_k127_210104_3	502025.Hoch_1914	5.197e-16	82.0	297WK@1|root,2ZV33@2|Bacteria,1P83J@1224|Proteobacteria,432YB@68525|delta/epsilon subdivisions,2WYBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_210104_0	502025.Hoch_5291	7.966e-229	714.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YU8H@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_2104568_2	69395.JQLZ01000003_gene493	4.766e-83	295.0	COG2159@1|root,COG2159@2|Bacteria,1PTY1@1224|Proteobacteria,2V5RF@28211|Alphaproteobacteria,2KHVI@204458|Caulobacterales	204458|Caulobacterales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_2104568_0	404589.Anae109_1843	1.446e-107	380.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_2104568_5	570967.JMLV01000012_gene3182	4.689e-14	84.0	COG1073@1|root,COG1073@2|Bacteria,1R4QH@1224|Proteobacteria,2UEVM@28211|Alphaproteobacteria,2JTKM@204441|Rhodospirillales	204441|Rhodospirillales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2104568_4	1172179.AUKV01000030_gene20	4.548e-37	162.0	COG1785@1|root,COG1785@2|Bacteria,2GM8A@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS3_k127_2104568_1	1278073.MYSTI_01712	2.961e-95	331.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1RAQ0@1224|Proteobacteria,42PCB@68525|delta/epsilon subdivisions,2X357@28221|Deltaproteobacteria,2YUBM@29|Myxococcales	28221|Deltaproteobacteria	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
CMS3_k127_2104568_3	1192034.CAP_0589	8.263e-81	274.0	COG0583@1|root,COG0583@2|Bacteria,1PKXJ@1224|Proteobacteria,43447@68525|delta/epsilon subdivisions,2X551@28221|Deltaproteobacteria,2Z04I@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_2110075_9	1278073.MYSTI_06674	0.0006689	46.0	COG0457@1|root,COG1629@1|root,COG0457@2|Bacteria,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria,2YU72@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
CMS3_k127_2110075_5	1242864.D187_000505	2.776e-74	286.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2110075_0	502025.Hoch_0293	0.0	1048.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YYWB@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS3_k127_2110075_7	399739.Pmen_3735	5.038e-61	222.0	COG1028@1|root,COG1028@2|Bacteria,1QTU9@1224|Proteobacteria,1RRP9@1236|Gammaproteobacteria,1YDX1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2110075_3	316055.RPE_3197	2.137e-114	376.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,2U1A9@28211|Alphaproteobacteria,3JXC0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_2110075_1	1002809.SSIL_2408	1.391e-204	652.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26DUZ@186818|Planococcaceae	91061|Bacilli	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_2110075_8	1313172.YM304_26220	3.958e-16	86.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_2110075_2	439235.Dalk_2599	5.981e-204	646.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,2MIGS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS3_k127_2110075_6	502025.Hoch_0218	1.668e-72	252.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2Z262@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
CMS3_k127_2110075_4	502025.Hoch_0219	6.291e-91	301.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2YWRT@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
CMS3_k127_2121119_3	502025.Hoch_6768	3.748e-15	76.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,2YW6Q@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
CMS3_k127_2121119_0	502025.Hoch_6767	6.357e-206	653.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YTXJ@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_2121119_1	1033802.SSPSH_003179	9.362e-152	516.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS3_k127_2121119_2	502025.Hoch_6765	9.863e-33	131.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,2YUP1@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
CMS3_k127_2134986_3	502025.Hoch_2639	4.026e-119	390.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,43B63@68525|delta/epsilon subdivisions,2X6JM@28221|Deltaproteobacteria,2YYC8@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS3_k127_2134986_13	502025.Hoch_6530	3.679e-29	124.0	2CGNA@1|root,3301B@2|Bacteria,1N74P@1224|Proteobacteria,42VID@68525|delta/epsilon subdivisions,2WRHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yippee-Mis18
CMS3_k127_2134986_7	1380394.JADL01000002_gene1794	2.388e-71	248.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,2JRW7@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
CMS3_k127_2134986_8	1123242.JH636434_gene3223	2.473e-65	233.0	COG0500@1|root,COG2226@2|Bacteria,2J0NE@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2134986_21	1121904.ARBP01000018_gene2687	1.063e-06	63.0	COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,47PNV@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_2134986_0	1207063.P24_13668	2.959e-171	548.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2JPC2@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_2134986_22	1170562.Cal6303_0331	2.166e-05	58.0	COG5485@1|root,COG5485@2|Bacteria,1GCZD@1117|Cyanobacteria,1HT70@1161|Nostocales	1117|Cyanobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_2134986_5	1192034.CAP_8869	2.419e-102	359.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2134986_20	983548.Krodi_1520	4.918e-08	68.0	COG3291@1|root,COG3291@2|Bacteria,4PKU5@976|Bacteroidetes,1IJEZ@117743|Flavobacteriia,37ERH@326319|Dokdonia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2134986_17	436308.Nmar_1047	2.942e-11	78.0	arCOG03561@1|root,arCOG05978@1|root,arCOG06534@1|root,arCOG03561@2157|Archaea,arCOG05978@2157|Archaea,arCOG06534@2157|Archaea	2157|Archaea	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,NHL,Tail_P2_I
CMS3_k127_2134986_19	1122605.KB893625_gene2206	5.154e-09	68.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF1566,FG-GAP,HemolysinCabind,Laminin_G_3,VCBS
CMS3_k127_2134986_6	502025.Hoch_3732	3.606e-79	271.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
CMS3_k127_2134986_14	502025.Hoch_3501	1.065e-28	124.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_2134986_2	502025.Hoch_3730	1.95e-122	412.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,42V3F@68525|delta/epsilon subdivisions,2WR8K@28221|Deltaproteobacteria,2YVGH@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ enzyme repeat	yfgL	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS3_k127_2134986_18	391625.PPSIR1_10300	3.1e-11	73.0	COG0457@1|root,COG0457@2|Bacteria,1N8F7@1224|Proteobacteria,42VYY@68525|delta/epsilon subdivisions,2WSH2@28221|Deltaproteobacteria,2Z2SG@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_8
CMS3_k127_2134986_1	502025.Hoch_3727	4.027e-170	555.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2YU6J@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS3_k127_2134986_4	502025.Hoch_3726	1.732e-117	386.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,2YYQ7@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS3_k127_2134986_11	1120949.KB903294_gene3757	3.04e-33	141.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DDFA@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2153448_4	502025.Hoch_4879	9.706e-37	162.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_2153448_0	502025.Hoch_1784	8.573e-242	787.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
CMS3_k127_2153448_5	682795.AciX8_1611	1.028e-10	73.0	COG5485@1|root,COG5485@2|Bacteria,3Y7UD@57723|Acidobacteria,2JN18@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_2153448_7	1385935.N836_00625	4.069e-08	65.0	COG5485@1|root,COG5485@2|Bacteria,1G6RM@1117|Cyanobacteria,1HDK8@1150|Oscillatoriales	1117|Cyanobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_2153448_1	867903.ThesuDRAFT_02160	2.746e-94	319.0	COG0627@1|root,COG2382@1|root,COG0627@2|Bacteria,COG2382@2|Bacteria,1VNKY@1239|Firmicutes	1239|Firmicutes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_2153448_3	1379270.AUXF01000001_gene2605	2.616e-43	182.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2153448_2	335543.Sfum_3525	1.024e-92	319.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,42Z3E@68525|delta/epsilon subdivisions,2WU93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_2188049_1	643648.Slip_0676	2.418e-135	442.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,42KFN@68298|Syntrophomonadaceae	186801|Clostridia	G	PFAM glycosyl transferase family 35	glgP2	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS3_k127_2188049_4	1278073.MYSTI_01311	3.402e-52	207.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS3_k127_2188049_2	502025.Hoch_3907	9.632e-122	412.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42R96@68525|delta/epsilon subdivisions,2WMVV@28221|Deltaproteobacteria,2YXAR@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS3_k127_2188049_0	502025.Hoch_5539	0.0	1052.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2YUFQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1,6.2.1.16	ko:K01895,ko:K01907	ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354,R01357	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_2188049_5	502025.Hoch_5540	2.758e-48	175.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,2YVDZ@29|Myxococcales	28221|Deltaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS3_k127_2188575_0	886293.Sinac_1156	1.51e-182	617.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2188575_1	502025.Hoch_5856	4.431e-155	496.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YURZ@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_2188575_3	96561.Dole_2193	1.109e-17	86.0	COG0451@1|root,COG0451@2|Bacteria,1PE5Z@1224|Proteobacteria,43A0H@68525|delta/epsilon subdivisions,2X262@28221|Deltaproteobacteria,2MN1V@213118|Desulfobacterales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_2192274_2	1254432.SCE1572_52185	1.318e-146	477.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
CMS3_k127_2192274_1	1254432.SCE1572_52185	2.24e-214	687.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
CMS3_k127_2192274_7	391625.PPSIR1_17160	1.394e-81	282.0	COG2340@1|root,COG2340@2|Bacteria,1Q6AW@1224|Proteobacteria,439IR@68525|delta/epsilon subdivisions,2X4V6@28221|Deltaproteobacteria,2YZNX@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_2192274_6	502025.Hoch_3698	2.408e-91	308.0	2BQ3I@1|root,32IXY@2|Bacteria,1PC2U@1224|Proteobacteria,435BB@68525|delta/epsilon subdivisions,2X97P@28221|Deltaproteobacteria,2Z2FH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2192274_5	502025.Hoch_3699	2.311e-96	325.0	2DCII@1|root,2ZE9Y@2|Bacteria,1PA1F@1224|Proteobacteria,433KQ@68525|delta/epsilon subdivisions,2WYI5@28221|Deltaproteobacteria,2YW5W@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2192274_3	502025.Hoch_3700	1.724e-135	441.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,2YY2A@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS3_k127_2192274_0	502025.Hoch_3702	0.0	1220.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2YU45@29|Myxococcales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS3_k127_2198699_3	248742.XP_005650816.1	2.135e-05	54.0	COG0484@1|root,KOG0715@2759|Eukaryota,37V11@33090|Viridiplantae,34HR2@3041|Chlorophyta	3041|Chlorophyta	O	DnaJ C terminal domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C
CMS3_k127_2198699_2	1219049.SP5_026_00060	3.211e-09	70.0	COG4206@1|root,COG4206@2|Bacteria,1R1WX@1224|Proteobacteria,2U0GK@28211|Alphaproteobacteria,2K1DC@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS3_k127_2198699_1	1265505.ATUG01000003_gene833	8.718e-11	75.0	COG4206@1|root,COG4206@2|Bacteria,1QVD1@1224|Proteobacteria,43BSV@68525|delta/epsilon subdivisions,2WK8I@28221|Deltaproteobacteria,2MJIT@213118|Desulfobacterales	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
CMS3_k127_2213412_0	502025.Hoch_3458	3.212e-177	571.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2YTZV@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
CMS3_k127_2213412_1	502025.Hoch_3287	7.622e-148	483.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2WN1R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
CMS3_k127_2217748_8	1303518.CCALI_00164	1.395e-24	113.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2217748_14	1227272.HMPREF1556_01841	0.0005415	48.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf,GtrA
CMS3_k127_2217748_9	1353529.M899_1948	1.968e-23	116.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2MSSN@213481|Bdellovibrionales,2WJCI@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_2217748_13	319225.Plut_1663	1.478e-14	83.0	COG1661@1|root,COG1661@2|Bacteria,1FFCY@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
CMS3_k127_2217748_6	502025.Hoch_4664	1.171e-47	174.0	COG0234@1|root,COG0234@2|Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	CarbopepD_reg_2,Cpn10,Plug,TonB_dep_Rec
CMS3_k127_2217748_2	472759.Nhal_1703	6.087e-143	459.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_2217748_0	1254432.SCE1572_00290	9.471e-243	764.0	COG0517@1|root,COG0517@2|Bacteria,1QZT1@1224|Proteobacteria,43CN4@68525|delta/epsilon subdivisions,2X7VC@28221|Deltaproteobacteria,2Z3IG@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_2217748_10	448385.sce4143	4.735e-21	111.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_2217748_11	1297742.A176_00288	1.279e-19	106.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WRIB@28221|Deltaproteobacteria,2YVSI@29|Myxococcales	28221|Deltaproteobacteria	S	CBS domain	-	-	-	ko:K04767,ko:K07168,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_2217748_7	526222.Desal_1806	3.072e-30	141.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WP5S@28221|Deltaproteobacteria,2MC10@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_2217748_12	1122621.ATZA01000014_gene3186	6.299e-15	91.0	COG1629@1|root,COG4771@2|Bacteria,4NJAM@976|Bacteroidetes,1IYZQ@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS3_k127_2217748_1	215803.DB30_0568	1.159e-158	539.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Pkinase_Tyr,WD40
CMS3_k127_2217748_5	234267.Acid_3693	1.864e-71	273.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y78P@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
CMS3_k127_2217748_3	1192034.CAP_5604	2.053e-114	385.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
CMS3_k127_2226825_0	502025.Hoch_3464	1.459e-178	582.0	COG1716@1|root,COG4962@1|root,COG1716@2|Bacteria,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,2YTSI@29|Myxococcales	28221|Deltaproteobacteria	TU	Type II IV secretion system protein	-	-	-	ko:K02283,ko:K03609	-	-	-	-	ko00000,ko02035,ko02044,ko03036,ko04812	-	-	-	CbiA,FHA,T2SSE
CMS3_k127_2226825_3	1123242.JH636435_gene1468	2.045e-06	58.0	COG0633@1|root,COG0633@2|Bacteria,2J14G@203682|Planctomycetes	203682|Planctomycetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
CMS3_k127_2226825_1	502025.Hoch_3767	1.407e-112	373.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2YV8J@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS3_k127_2231032_1	502025.Hoch_4271	1.411e-92	308.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2YUBT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS3_k127_2231032_0	391625.PPSIR1_36202	7.873e-105	348.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria,2YV4I@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C7
CMS3_k127_224066_18	502025.Hoch_5318	1.402e-27	120.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2YVDP@29|Myxococcales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS3_k127_224066_15	502025.Hoch_5317	3.577e-57	203.0	2ANM7@1|root,31DKH@2|Bacteria,1QAWY@1224|Proteobacteria,435CB@68525|delta/epsilon subdivisions,2WZPX@28221|Deltaproteobacteria,2Z2HJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_224066_6	502025.Hoch_5506	3.95e-145	465.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WKFV@28221|Deltaproteobacteria,2YUS4@29|Myxococcales	28221|Deltaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	dppB	-	-	ko:K02033,ko:K12369,ko:K13890	ko02010,ko02024,map02010,map02024	M00239,M00324,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1
CMS3_k127_224066_12	1125863.JAFN01000001_gene1630	1.76e-69	256.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,43AQ5@68525|delta/epsilon subdivisions,2X63Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_224066_17	502025.Hoch_5508	5.573e-29	119.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	tmoC	-	-	ko:K05710,ko:K15762,ko:K22360	ko00360,ko00623,ko00625,ko00920,ko01100,ko01120,ko01220,map00360,map00623,map00625,map00920,map01100,map01120,map01220	M00538,M00545	R02550,R03562,R05444,R05666,R06782,R06783,R09513,R11901	RC00098,RC00269,RC00490,RC01383,RC02556	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
CMS3_k127_224066_22	1042209.HK44_005175	1.876e-10	73.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1YS2P@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_224066_14	1192034.CAP_6990	1.043e-57	229.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_224066_24	1150398.JIBJ01000021_gene3727	1.068e-05	59.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
CMS3_k127_224066_3	502025.Hoch_4229	9.575e-154	490.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2YURS@29|Myxococcales	28221|Deltaproteobacteria	T	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_224066_8	502025.Hoch_4228	3.127e-118	402.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2YURS@29|Myxococcales	28221|Deltaproteobacteria	T	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_224066_20	1206733.BAGC01000047_gene2398	2.275e-12	77.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria,4G8M2@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Lpp-LpqN,Pkinase
CMS3_k127_224066_5	502025.Hoch_4227	3.565e-149	476.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,431UR@68525|delta/epsilon subdivisions,2WWZQ@28221|Deltaproteobacteria,2YU65@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
CMS3_k127_224066_9	502025.Hoch_4226	2.38e-101	344.0	COG1075@1|root,COG1075@2|Bacteria,1R75P@1224|Proteobacteria,42QNM@68525|delta/epsilon subdivisions,2WN41@28221|Deltaproteobacteria,2Z16B@29|Myxococcales	28221|Deltaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
CMS3_k127_224066_4	502025.Hoch_4224	6.165e-153	508.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_4224|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_224066_7	502025.Hoch_3956	2.678e-119	398.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_224066_2	502025.Hoch_4222	1.025e-162	537.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_224066_0	502025.Hoch_5509	1.829e-225	736.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,43C0B@68525|delta/epsilon subdivisions,2X7B2@28221|Deltaproteobacteria,2Z3EU@29|Myxococcales	28221|Deltaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS3_k127_224066_16	1123242.JH636436_gene105	5.676e-33	141.0	COG1595@1|root,COG1595@2|Bacteria,2IZWS@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_224066_23	502025.Hoch_5628	2.237e-10	65.0	2B5QI@1|root,31YK3@2|Bacteria,1QKC7@1224|Proteobacteria,434W3@68525|delta/epsilon subdivisions,2X91T@28221|Deltaproteobacteria,2Z1GU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_224066_1	446470.Snas_1978	9.939e-209	662.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EZWJ@85014|Glycomycetales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_224066_19	760117.JN27_23190	9.25e-16	91.0	COG1555@1|root,COG1555@2|Bacteria,1NW2I@1224|Proteobacteria	1224|Proteobacteria	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_224066_10	452637.Oter_2419	8.751e-89	315.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia,3K744@414999|Opitutae	414999|Opitutae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS3_k127_224066_11	1192034.CAP_8072	5.453e-87	297.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2X5XK@28221|Deltaproteobacteria,2Z2YK@29|Myxococcales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	appB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS3_k127_224066_13	595460.RRSWK_03719	4.119e-69	259.0	COG4166@1|root,COG4166@2|Bacteria,2IY5J@203682|Planctomycetes	203682|Planctomycetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_2245138_12	1125863.JAFN01000001_gene1012	4.695e-27	117.0	COG2834@1|root,COG2834@2|Bacteria,1NEDP@1224|Proteobacteria,43117@68525|delta/epsilon subdivisions,2WWFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2245138_2	448385.sce0363	6.098e-105	361.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2245138_16	188626.HMPREF0321_0591	4.661e-07	61.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,1ZWMH@145357|Dermacoccaceae	201174|Actinobacteria	V	Forkhead associated domain	-	-	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
CMS3_k127_2245138_17	1317118.ATO8_08021	2.385e-06	59.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,4KKNG@93682|Roseivivax	28211|Alphaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS3_k127_2245138_8	530564.Psta_0573	2.231e-47	179.0	COG1409@1|root,COG1409@2|Bacteria,2IX9N@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_2245138_18	935836.JAEL01000087_gene4700	0.0004386	50.0	COG1409@1|root,COG2931@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,1TPQQ@1239|Firmicutes,4HC2W@91061|Bacilli,1ZCF0@1386|Bacillus	91061|Bacilli	Q	Calcineurin-like phosphoesterase	yvnB	-	-	-	-	-	-	-	-	-	-	-	LTD,Metallophos,SLH,fn3
CMS3_k127_2245138_0	886293.Sinac_1156	8.588e-299	963.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2245138_4	1515746.HR45_11315	3.254e-79	295.0	COG3303@1|root,COG3303@2|Bacteria,1NNDS@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2245138_6	443255.SCLAV_2726	5.564e-61	226.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	MA20_06765	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_2245138_1	1038859.AXAU01000010_gene1876	7.363e-110	371.0	COG4977@1|root,COG4977@2|Bacteria,1RC4M@1224|Proteobacteria,2TXCQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator, araC family	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18,HTH_AraC
CMS3_k127_2245138_5	1452718.JBOY01000063_gene2589	2.003e-62	222.0	COG2818@1|root,COG2818@2|Bacteria,1R3WB@1224|Proteobacteria,1RSAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	3-Methyladenine DNA glycosylase	IV02_03670	-	-	-	-	-	-	-	-	-	-	-	Adenine_glyco
CMS3_k127_2245138_9	985867.AEWF01000005_gene2494	2.476e-36	158.0	2AJXV@1|root,31AM0@2|Bacteria,1NWT9@1224|Proteobacteria,2US52@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2245138_13	448385.sce0520	2.518e-14	85.0	COG3391@1|root,COG3391@2|Bacteria,1R0BE@1224|Proteobacteria,43CTP@68525|delta/epsilon subdivisions,2X817@28221|Deltaproteobacteria,2Z05E@29|Myxococcales	28221|Deltaproteobacteria	E	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
CMS3_k127_2245138_3	1192034.CAP_8613	5.407e-84	295.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_2245138_15	502025.Hoch_6888	3.686e-11	74.0	COG0745@1|root,COG0810@1|root,COG0745@2|Bacteria,COG0810@2|Bacteria,1NVZF@1224|Proteobacteria,42ZUK@68525|delta/epsilon subdivisions,2X7NR@28221|Deltaproteobacteria,2Z3H7@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,Response_reg
CMS3_k127_2245138_14	797302.Halru_2437	1.238e-13	84.0	COG1361@1|root,COG1520@1|root,COG3291@1|root,COG3979@1|root,arCOG02088@1|root,arCOG07560@1|root,arCOG10954@1|root,arCOG02088@2157|Archaea,arCOG02492@2157|Archaea,arCOG02508@2157|Archaea,arCOG04400@2157|Archaea,arCOG07560@2157|Archaea,arCOG07581@2157|Archaea,arCOG10954@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD,PQQ_2,PQQ_3
CMS3_k127_2245138_11	35128.Thaps8031	1.485e-31	136.0	2F9Q6@1|root,2TAVY@2759|Eukaryota,2XHJM@2836|Bacillariophyta	2836|Bacillariophyta	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
CMS3_k127_2245138_7	526227.Mesil_2652	2.393e-51	198.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	bioH	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_2245138_10	1157708.KB907450_gene5482	1.019e-33	136.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2VSF5@28216|Betaproteobacteria,4AJFD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
CMS3_k127_225634_1	1254432.SCE1572_13050	1.028e-127	419.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,43BBS@68525|delta/epsilon subdivisions,2X6QY@28221|Deltaproteobacteria,2YU79@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS3_k127_225634_2	1242864.D187_010151	3.833e-53	203.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,42VAD@68525|delta/epsilon subdivisions,2WRMT@28221|Deltaproteobacteria,2YVSE@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
CMS3_k127_225634_0	1380394.JADL01000002_gene1789	6.54e-148	475.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TQSC@28211|Alphaproteobacteria,2JREM@204441|Rhodospirillales	204441|Rhodospirillales	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_2261044_8	448385.sce9349	3.547e-86	313.0	COG3055@1|root,COG5184@1|root,COG3055@2|Bacteria,COG5184@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2261044_25	655815.ZPR_2204	3.967e-12	73.0	298QN@1|root,2ZVV0@2|Bacteria,4NNRX@976|Bacteroidetes,1I2A6@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2261044_6	7739.XP_002606139.1	1.386e-92	327.0	KOG1216@1|root,KOG1217@1|root,KOG1216@2759|Eukaryota,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,48CY1@7711|Chordata	33208|Metazoa	T	EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_3,EGF_CA,Lectin_C,TIL
CMS3_k127_2261044_24	1121381.JNIV01000059_gene3891	8.045e-23	110.0	COG2372@1|root,COG3325@1|root,COG2372@2|Bacteria,COG3325@2|Bacteria,1WN17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
CMS3_k127_2261044_27	448385.sce2833	9.172e-06	57.0	COG3055@1|root,COG5184@1|root,COG3055@2|Bacteria,COG5184@2|Bacteria,1NCZK@1224|Proteobacteria,43C3B@68525|delta/epsilon subdivisions,2X7DY@28221|Deltaproteobacteria,2Z0HN@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	mtsC	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_2261044_7	502025.Hoch_5491	4.222e-88	297.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,437RC@68525|delta/epsilon subdivisions,2X304@28221|Deltaproteobacteria,2YTVQ@29|Myxococcales	28221|Deltaproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PCMT
CMS3_k127_2261044_12	272560.BPSS0985	3.541e-67	231.0	COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2VQN8@28216|Betaproteobacteria,1K88K@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_2261044_18	502025.Hoch_4289	3.257e-40	156.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2261044_0	1124780.ANNU01000036_gene34	1.2e-206	666.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,47M9P@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
CMS3_k127_2261044_26	502025.Hoch_1914	5.868e-10	64.0	297WK@1|root,2ZV33@2|Bacteria,1P83J@1224|Proteobacteria,432YB@68525|delta/epsilon subdivisions,2WYBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2261044_9	502025.Hoch_6757	1.739e-81	287.0	COG2957@1|root,COG2957@2|Bacteria,1PY5A@1224|Proteobacteria,43E1A@68525|delta/epsilon subdivisions,2WZER@28221|Deltaproteobacteria,2Z1ZA@29|Myxococcales	28221|Deltaproteobacteria	E	Porphyromonas-type peptidyl-arginine deiminase	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CMS3_k127_2261044_5	530564.Psta_3806	1.926e-99	336.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_2261044_19	65393.PCC7424_0613	3.554e-40	166.0	COG4067@1|root,COG4067@2|Bacteria,1G6KI@1117|Cyanobacteria,3KI1C@43988|Cyanothece	1117|Cyanobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS3_k127_2261044_4	1120958.AULD01000006_gene438	8.244e-102	341.0	COG3608@1|root,COG3608@2|Bacteria,2IC8T@201174|Actinobacteria	201174|Actinobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS3_k127_2261044_3	459495.SPLC1_S010310	1.039e-137	444.0	COG0189@1|root,COG0189@2|Bacteria,1G0DT@1117|Cyanobacteria,1H6ZT@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,Zn_protease
CMS3_k127_2261044_2	1144275.COCOR_05301	1.153e-143	489.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria	1224|Proteobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS3_k127_2261044_10	1191523.MROS_1522	1.095e-77	275.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_2261044_1	448385.sce7801	2.934e-157	509.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P6D@68525|delta/epsilon subdivisions,2WM1P@28221|Deltaproteobacteria,2YUD4@29|Myxococcales	28221|Deltaproteobacteria	T	DNA-binding response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2261044_11	945713.IALB_2307	3.191e-72	256.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2,Peptidase_C70,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_2261044_16	1048339.KB913029_gene1756	2.975e-51	190.0	28IGY@1|root,2Z8I9@2|Bacteria,2H6U5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2261044_21	502025.Hoch_3239	1.494e-31	143.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
CMS3_k127_2261044_13	1254432.SCE1572_27875	1.393e-64	245.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36
CMS3_k127_2261044_15	566461.SSFG_02651	2.552e-53	211.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_2261044_14	985054.JQEZ01000003_gene1363	1.711e-60	215.0	COG1216@1|root,COG1216@2|Bacteria,1QY6A@1224|Proteobacteria,2TXHY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2261044_22	903818.KI912268_gene2788	1.658e-24	110.0	COG2885@1|root,COG2885@2|Bacteria,3Y5IQ@57723|Acidobacteria	57723|Acidobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF937,OmpA
CMS3_k127_2261044_17	404589.Anae109_2327	3.653e-47	192.0	COG3506@1|root,COG5276@1|root,COG3506@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
CMS3_k127_2265258_5	1282876.BAOK01000002_gene502	1.606e-72	273.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_2265258_1	391625.PPSIR1_15340	4.573e-198	644.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_2265258_2	391625.PPSIR1_15345	1.713e-165	551.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YUT4@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG-2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2265258_4	391625.PPSIR1_15350	2.474e-105	364.0	COG2030@1|root,COG2030@2|Bacteria,1RAAG@1224|Proteobacteria,42RIX@68525|delta/epsilon subdivisions,2WNJI@28221|Deltaproteobacteria,2Z2RH@29|Myxococcales	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_2265258_0	391625.PPSIR1_15355	2.838e-265	841.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42MUH@68525|delta/epsilon subdivisions,2WJ16@28221|Deltaproteobacteria,2YU4C@29|Myxococcales	28221|Deltaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2265258_6	391625.PPSIR1_15360	1.895e-63	223.0	COG1309@1|root,COG1309@2|Bacteria,1Q5BW@1224|Proteobacteria,42TMA@68525|delta/epsilon subdivisions,2WZPQ@28221|Deltaproteobacteria,2Z2HA@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_2265258_3	756272.Plabr_3034	9.759e-147	478.0	COG0591@1|root,COG0591@2|Bacteria,2J22E@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS3_k127_2272310_4	583355.Caka_0186	8.11e-15	79.0	2CCSR@1|root,30U27@2|Bacteria,46Y6M@74201|Verrucomicrobia,3K9T2@414999|Opitutae	414999|Opitutae	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS3_k127_2272310_1	391625.PPSIR1_20349	2.549e-138	475.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_2272310_6	1278073.MYSTI_05946	1.818e-07	64.0	COG4733@1|root,COG4932@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,TIG
CMS3_k127_2272310_5	883126.HMPREF9710_03146	2.728e-08	65.0	COG0745@1|root,COG0745@2|Bacteria,1RJB3@1224|Proteobacteria,2VRB3@28216|Betaproteobacteria	28216|Betaproteobacteria	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
CMS3_k127_2272310_0	502025.Hoch_5906	1.248e-138	443.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,43AG6@68525|delta/epsilon subdivisions,2X63V@28221|Deltaproteobacteria,2Z38Y@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	PP2C_2
CMS3_k127_2272310_2	502025.Hoch_5905	6.324e-88	295.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2YUQX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS3_k127_2277965_15	1229780.BN381_50061	3.017e-77	279.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,3UWHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_2277965_36	1234664.AMRO01000022_gene1586	6.194e-35	141.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1V1C5@1239|Firmicutes,4HG15@91061|Bacilli,1WHD7@129337|Geobacillus	91061|Bacilli	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20,HTH_5
CMS3_k127_2277965_53	1229172.JQFA01000004_gene1016	9.408e-06	54.0	2C1W2@1|root,31MWG@2|Bacteria,1G6PN@1117|Cyanobacteria,1HFVT@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_2277965_43	888050.HMPREF9004_0475	2.693e-18	100.0	COG2755@1|root,COG3291@1|root,COG2755@2|Bacteria,COG3291@2|Bacteria,2IEXF@201174|Actinobacteria,4D34K@85005|Actinomycetales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2,PKD,VWA
CMS3_k127_2277965_20	323850.Shew_3096	1.077e-71	259.0	COG3291@1|root,COG3291@2|Bacteria,1NE5Q@1224|Proteobacteria,1TCNR@1236|Gammaproteobacteria,2Q8VQ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
CMS3_k127_2277965_1	886293.Sinac_1156	5.564e-185	631.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2277965_32	1089550.ATTH01000001_gene1830	8.285e-40	170.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_2277965_22	935261.JAGL01000032_gene3808	9.88e-63	227.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,43JDB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_2277965_48	1286632.P278_00680	6.102e-09	66.0	COG5553@1|root,COG5553@2|Bacteria,4NJMB@976|Bacteroidetes,1I0CQ@117743|Flavobacteriia	976|Bacteroidetes	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2277965_6	502025.Hoch_3553	2.329e-148	514.0	COG2067@1|root,COG2067@2|Bacteria,1Q2WT@1224|Proteobacteria,438JN@68525|delta/epsilon subdivisions,2X3UB@28221|Deltaproteobacteria,2YX4H@29|Myxococcales	28221|Deltaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_2277965_0	502025.Hoch_3552	6.209e-240	783.0	2AIZE@1|root,319HE@2|Bacteria,1Q2SG@1224|Proteobacteria,438E3@68525|delta/epsilon subdivisions,2X3P8@28221|Deltaproteobacteria,2YWR0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2277965_31	1445613.JALM01000009_gene746	2.573e-40	158.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria,4E5PB@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2277965_11	246197.MXAN_4935	7.417e-106	355.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_2277965_13	350058.Mvan_1079	1.72e-84	291.0	COG0596@1|root,COG0596@2|Bacteria,2HEN1@201174|Actinobacteria,23ABM@1762|Mycobacteriaceae	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_2277965_2	350058.Mvan_1080	1.405e-183	604.0	COG0318@1|root,COG0318@2|Bacteria,2GJR0@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,Abhydrolase_1
CMS3_k127_2277965_25	497964.CfE428DRAFT_2280	8.287e-52	204.0	COG1680@1|root,COG1680@2|Bacteria,46SS8@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_2277965_44	2002.JOEQ01000005_gene3505	8.191e-17	88.0	COG1309@1|root,COG1309@2|Bacteria,2I16R@201174|Actinobacteria,4EM5K@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2277965_7	1033730.CAHG01000014_gene1649	1.963e-139	465.0	COG1960@1|root,COG1960@2|Bacteria,2GJH2@201174|Actinobacteria,4DNJZ@85009|Propionibacteriales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE24	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2277965_3	479435.Kfla_4557	3.873e-170	544.0	COG1960@1|root,COG1960@2|Bacteria,2GNBW@201174|Actinobacteria,4DNDM@85009|Propionibacteriales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE23	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
CMS3_k127_2277965_34	67593.Physo142753	1.028e-37	163.0	29I6F@1|root,2RRDG@2759|Eukaryota,3Q9C9@4776|Peronosporales	4776|Peronosporales	S	Transglutaminase elicitor	-	-	-	-	-	-	-	-	-	-	-	-	TGase_elicitor
CMS3_k127_2277965_37	1043205.AFYF01000022_gene752	5.052e-30	126.0	COG1309@1|root,COG1309@2|Bacteria,2IKPS@201174|Actinobacteria,4FI03@85021|Intrasporangiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2277965_18	1169152.AXVD01000023_gene3256	5.394e-74	259.0	COG2021@1|root,COG2021@2|Bacteria,2HIEG@201174|Actinobacteria,4G3VG@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_2277965_26	590998.Celf_3186	3.365e-47	188.0	COG0189@1|root,COG0189@2|Bacteria,2I8TP@201174|Actinobacteria	201174|Actinobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
CMS3_k127_2277965_24	290397.Adeh_2304	2.266e-55	197.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3,1.8.5.5	ko:K07306,ko:K08352	ko00920,ko01120,map00920,map01120	-	R09501,R10149	RC02555,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_2277965_35	448385.sce3602	6.863e-37	161.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.3.5,3.2.1.14	ko:K01081,ko:K01183,ko:K20276	ko00230,ko00240,ko00520,ko00760,ko01100,ko01110,ko02024,map00230,map00240,map00520,map00760,map01100,map01110,map02024	-	R00183,R00511,R00963,R01126,R01206,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02334,R02719,R03346	RC00017,RC00467	ko00000,ko00001,ko01000	-	GH18	-	F5_F8_type_C,Melibiase_2,NPCBM_assoc,PKD,PPC,Trypsin_2,VPEP
CMS3_k127_2277965_27	1265505.ATUG01000001_gene4392	8.972e-47	173.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
CMS3_k127_2277965_28	1254432.SCE1572_35015	1.985e-45	172.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2277965_4	266264.Rmet_3598	1.376e-166	537.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2VMQV@28216|Betaproteobacteria,1K01B@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Flavin-binding monooxygenase-like	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
CMS3_k127_2277965_16	1177154.Y5S_01689	2.066e-76	264.0	COG0300@1|root,COG0300@2|Bacteria,1R8JY@1224|Proteobacteria,1RZWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2277965_9	935866.JAER01000007_gene384	1.046e-124	413.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4DPW6@85009|Propionibacteriales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
CMS3_k127_2277965_51	290317.Cpha266_0148	9.796e-07	59.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS3_k127_2277965_17	671143.DAMO_1669	1.885e-74	275.0	COG0845@1|root,COG2010@1|root,COG0845@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,FIVAR,HlyD_3,PA14,RNA_pol_Rpb1_5
CMS3_k127_2277965_8	671143.DAMO_0768	4.171e-132	432.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS3_k127_2277965_38	1232410.KI421413_gene911	1.24e-26	122.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria,43UPC@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Rieske [2Fe-2S] domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS3_k127_2277965_5	671143.DAMO_0766	3.278e-157	516.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	pcmB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	ko:K03388,ko:K12527	ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R07229,R11928,R11931,R11943,R11944	RC00011,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,FlpD,Pyr_redox_2,Pyr_redox_3
CMS3_k127_2277965_29	331678.Cphamn1_0650	5.962e-45	171.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2277965_21	177439.DP1040	9.029e-67	246.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2277965_39	237368.SCABRO_00535	1.02e-25	121.0	COG3637@1|root,COG3637@2|Bacteria,2J46X@203682|Planctomycetes	203682|Planctomycetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2277965_47	1535422.ND16A_1233	3.053e-11	76.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2277965_52	203275.BFO_0574	5.753e-06	59.0	COG5492@1|root,COG5492@2|Bacteria,4NJ9A@976|Bacteroidetes,2FU7J@200643|Bacteroidia,230YV@171551|Porphyromonadaceae	976|Bacteroidetes	N	Bacterial group 2 Ig-like protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Big_2,F5_F8_type_C,LRR_5,Polysacc_deac_3
CMS3_k127_2277965_46	1120956.JHZK01000001_gene3395	3.018e-15	89.0	2C5N8@1|root,33T7S@2|Bacteria,1NRCN@1224|Proteobacteria,2UN4U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2277965_45	797114.C475_07380	7.168e-16	89.0	COG1520@1|root,arCOG02556@2157|Archaea	2157|Archaea	O	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PQQ_2,PQQ_3
CMS3_k127_2277965_40	557599.MKAN_03995	6.131e-24	116.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM,DUF3225,DUF4440,SnoaL_2,SnoaL_3
CMS3_k127_2277965_30	316057.RPD_3316	1.803e-44	180.0	COG2030@1|root,COG2030@2|Bacteria,1RFHT@1224|Proteobacteria,2UKBG@28211|Alphaproteobacteria,3K446@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_2277965_33	1463934.JOCF01000070_gene4128	5.279e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,2IT26@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2277965_10	502025.Hoch_1344	8.69e-116	379.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,43AK0@68525|delta/epsilon subdivisions,2X60A@28221|Deltaproteobacteria,2Z0EU@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_2277965_14	1121875.KB907548_gene1476	7.341e-78	266.0	COG5553@1|root,COG5553@2|Bacteria,4NJMB@976|Bacteroidetes,1I0CQ@117743|Flavobacteriia	976|Bacteroidetes	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2277965_50	208439.AJAP_33010	9.24e-08	61.0	2C73B@1|root,330Z7@2|Bacteria,2IIMQ@201174|Actinobacteria,4E6EA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
CMS3_k127_2277965_19	1038869.AXAN01000035_gene2174	7.24e-72	258.0	COG0346@1|root,COG0346@2|Bacteria,1P5FR@1224|Proteobacteria,2VP8J@28216|Betaproteobacteria,1K62Z@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	bphC	-	1.13.11.39	ko:K00462	ko00361,ko00621,ko01100,ko01120,ko01220,map00361,map00621,map01100,map01120,map01220	M00543	R03462,R05245,R07827	RC00387,RC01306	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS3_k127_2277965_23	1502724.FF80_03546	7.346e-58	213.0	COG2207@1|root,COG2207@2|Bacteria,1RAAS@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02508	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18
CMS3_k127_2277965_12	518766.Rmar_0830	9.631e-101	345.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1FJ4A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
CMS3_k127_2302664_5	502025.Hoch_3451	3.929e-09	57.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2YUHB@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS3_k127_2302664_1	502025.Hoch_5345	9.259e-133	451.0	COG4547@1|root,COG4547@2|Bacteria	2|Bacteria	H	Cobalamin biosynthesis protein CobT VWA domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin_3,CobT_C,DUF11,DUF4347,He_PIG,SprB,VWA
CMS3_k127_2302664_4	266117.Rxyl_1257	1.107e-45	176.0	COG0697@1|root,COG0697@2|Bacteria,2I198@201174|Actinobacteria,4CQSW@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_2302664_3	56110.Oscil6304_1527	5.618e-64	231.0	COG1808@1|root,COG1808@2|Bacteria,1GCGN@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
CMS3_k127_2302664_0	502025.Hoch_5344	5.804e-243	761.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2YU9T@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS3_k127_2322615_1	1232410.KI421413_gene620	1.369e-69	246.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42NID@68525|delta/epsilon subdivisions,2WJ4P@28221|Deltaproteobacteria,43S91@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	C-terminal domain of tail specific protease (DUF3340)	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CMS3_k127_2322615_3	670487.Ocepr_1854	8.226e-29	134.0	COG3221@1|root,COG3221@2|Bacteria,1WIG6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_2322615_2	1242864.D187_003283	2.74e-48	195.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_2322615_0	502025.Hoch_3417	1.984e-194	627.0	COG4292@1|root,COG4292@2|Bacteria,1QWAK@1224|Proteobacteria,42ZNP@68525|delta/epsilon subdivisions,2WUUY@28221|Deltaproteobacteria,2Z1WT@29|Myxococcales	28221|Deltaproteobacteria	S	K channel, inward rectifier	-	-	-	-	-	-	-	-	-	-	-	-	IRK,LtrA
CMS3_k127_2322991_4	246197.MXAN_4196	2.923e-19	90.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUB5@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2322991_1	316056.RPC_1656	1.518e-86	295.0	COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,2TRY2@28211|Alphaproteobacteria,3JSW4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	MA20_16685	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_2322991_0	477641.MODMU_2570	9.188e-99	334.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_2322991_2	1242864.D187_004584	1.053e-45	172.0	COG3148@1|root,COG3148@2|Bacteria	2|Bacteria	S	PFAM DTW domain containing protein	-	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
CMS3_k127_2322991_3	502025.Hoch_0315	1.455e-43	162.0	COG1597@1|root,COG1597@2|Bacteria,1PV0P@1224|Proteobacteria,42XZR@68525|delta/epsilon subdivisions,2WTF1@28221|Deltaproteobacteria,2YVY3@29|Myxococcales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_2337656_6	7222.FBpp0147649	2.859e-35	156.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera,45XHP@7214|Drosophilidae	33208|Metazoa	T	Calcium ion binding	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
CMS3_k127_2337656_10	502025.Hoch_4223	5.131e-10	65.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,439A0@68525|delta/epsilon subdivisions,2X4HG@28221|Deltaproteobacteria,2YZ10@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_2337656_8	1246995.AFR_06495	6.86e-12	72.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria,4DD9V@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigC	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2337656_9	502025.Hoch_4223	4.565e-11	68.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,439A0@68525|delta/epsilon subdivisions,2X4HG@28221|Deltaproteobacteria,2YZ10@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_2337656_3	448385.sce4033	8.888e-83	291.0	2AJ10@1|root,319J4@2|Bacteria,1Q2X4@1224|Proteobacteria,438K5@68525|delta/epsilon subdivisions,2X3UQ@28221|Deltaproteobacteria,2YX5Z@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2337656_2	502025.Hoch_4569	1.256e-89	315.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2337656_0	483219.LILAB_34455	6.196e-97	344.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CMS3_k127_2337656_1	1254432.SCE1572_50660	2.256e-95	330.0	2DBEW@1|root,2Z8UY@2|Bacteria,1QZEI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
CMS3_k127_2337656_4	1242864.D187_010119	5.799e-67	242.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_2337656_5	237368.SCABRO_00780	2.002e-63	234.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_2394690_0	391625.PPSIR1_25711	2.136e-115	390.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_2397393_2	502025.Hoch_5820	1.05e-17	89.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
CMS3_k127_2397393_0	1037409.BJ6T_01310	1.994e-70	254.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
CMS3_k127_2397393_1	502025.Hoch_4902	8.031e-55	202.0	COG1073@1|root,COG1073@2|Bacteria,1NKA5@1224|Proteobacteria,438I9@68525|delta/epsilon subdivisions,2X9SF@28221|Deltaproteobacteria,2YX1V@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_24174_6	1168065.DOK_09474	2.086e-54	202.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,1S1Y6@1236|Gammaproteobacteria,1J5HR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_24174_4	1278073.MYSTI_04826	8.325e-68	239.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria	1224|Proteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_24174_3	1137799.GZ78_07390	4.152e-85	294.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,1S10S@1236|Gammaproteobacteria,1XS6U@135619|Oceanospirillales	135619|Oceanospirillales	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_24174_1	1254432.SCE1572_06465	5.063e-196	659.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_24174_2	1278073.MYSTI_04820	4.416e-189	606.0	COG0318@1|root,COG0318@2|Bacteria,1MVJ1@1224|Proteobacteria	1224|Proteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_24174_0	1278073.MYSTI_04815	1.222e-203	645.0	COG0318@1|root,COG0318@2|Bacteria,1PG0N@1224|Proteobacteria,42ZGH@68525|delta/epsilon subdivisions,2WUZC@28221|Deltaproteobacteria,2YXZH@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_24174_5	1144325.PMI22_00764	1.266e-67	244.0	COG4221@1|root,COG4221@2|Bacteria,1MV0A@1224|Proteobacteria,1S2V4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2429986_4	1226994.AMZB01000124_gene2974	2.827e-05	55.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1YG59@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	gag-polyprotein putative aspartyl protease	orf	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS3_k127_2429986_3	502025.Hoch_6706	3.99e-51	185.0	2DBZS@1|root,2ZC3A@2|Bacteria,1Q9YR@1224|Proteobacteria,434PU@68525|delta/epsilon subdivisions,2WZ15@28221|Deltaproteobacteria,2Z13E@29|Myxococcales	28221|Deltaproteobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2429986_0	502025.Hoch_6707	7.708e-183	597.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CMS3_k127_2429986_2	502025.Hoch_6708	1.143e-79	274.0	COG3770@1|root,COG3770@2|Bacteria	502025.Hoch_6708|-	M	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2429986_1	502025.Hoch_0045	8.145e-100	328.0	COG1595@1|root,COG1595@2|Bacteria,1QCRA@1224|Proteobacteria,435KP@68525|delta/epsilon subdivisions,2X9B1@28221|Deltaproteobacteria,2Z12M@29|Myxococcales	28221|Deltaproteobacteria	K	RNA polymerase	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2431122_4	886293.Sinac_1156	1.372e-120	409.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2431122_3	1216976.AX27061_4763	3.853e-132	424.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2VJ36@28216|Betaproteobacteria,3T5GY@506|Alcaligenaceae	28216|Betaproteobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	-	ko:K07536	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05592	RC01429	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_2431122_7	762376.AXYL_06680	1.643e-89	302.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2VHMD@28216|Betaproteobacteria,3T28I@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2431122_11	44056.XP_009039197.1	1.025e-56	210.0	COG1024@1|root,KOG1680@2759|Eukaryota	2759|Eukaryota	I	enoyl-CoA hydratase activity	-	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2431122_16	266117.Rxyl_2334	2.049e-08	61.0	COG2050@1|root,COG2050@2|Bacteria,2HRUJ@201174|Actinobacteria,4CTY0@84995|Rubrobacteria	84995|Rubrobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_2431122_15	1869.MB27_17385	1.651e-23	108.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria,4DBHA@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	kstR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_2431122_14	290397.Adeh_3980	1.962e-24	119.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria,2Z2J1@29|Myxococcales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
CMS3_k127_2431122_12	880073.Calab_1130	2.338e-53	213.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
CMS3_k127_2431122_6	1278073.MYSTI_04827	7.907e-109	358.0	COG1024@1|root,COG1024@2|Bacteria,1R3Q4@1224|Proteobacteria	1224|Proteobacteria	I	Enoyl-CoA hydratase	-	-	4.1.2.41,4.2.1.101,4.2.1.17	ko:K01692,ko:K18383	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R05772,R05773,R06411,R06412,R06942,R08093	RC00307,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC01468,RC01828,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_2431122_0	1278073.MYSTI_04828	6.701e-147	476.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,438NC@68525|delta/epsilon subdivisions,2X3WD@28221|Deltaproteobacteria,2YXBV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	1.14.13.151,1.14.15.14	ko:K05525,ko:K20497	ko00902,ko01110,map00902,map01110	-	R04366,R09922,R09923,R09924,R09925	RC01137,RC02561,RC02626	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
CMS3_k127_2431122_2	83406.HDN1F_27120	1.13e-137	447.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,1RMG8@1236|Gammaproteobacteria,1J83M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.14.12	ko:K16047	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2431122_10	1121933.AUHH01000008_gene1129	1.735e-72	269.0	COG0346@1|root,COG0346@2|Bacteria,2GM8H@201174|Actinobacteria,4DUS6@85009|Propionibacteriales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2431122_8	1137799.GZ78_07325	3.35e-82	298.0	COG2267@1|root,COG2267@2|Bacteria,1MZG8@1224|Proteobacteria,1RQYM@1236|Gammaproteobacteria,1XMAT@135619|Oceanospirillales	135619|Oceanospirillales	I	3-oxoacyl-ACP reductase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_2431122_5	1005395.CSV86_08366	1.432e-109	376.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	hydratase	xylJ	-	4.2.1.132,4.2.1.80	ko:K18364	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R02601,R05864	RC00750,RC02676	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
CMS3_k127_2431122_1	85643.Tmz1t_3106	3.681e-142	455.0	COG4569@1|root,COG4569@2|Bacteria,1MV23@1224|Proteobacteria,2VMVU@28216|Betaproteobacteria,2KV1Q@206389|Rhodocyclales	206389|Rhodocyclales	Q	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds	-	-	1.2.1.10,1.2.1.87	ko:K18366	ko00362,ko00620,ko00621,ko00622,ko00650,ko01100,ko01120,ko01220,map00362,map00620,map00621,map00622,map00650,map01100,map01120,map01220	M00569	R00228,R01172,R09097	RC00004,RC00184,RC01195	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	AcetDehyd-dimer,Semialdhyde_dh
CMS3_k127_2431122_13	1122201.AUAZ01000005_gene631	1.355e-41	174.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,4662D@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds	mhpE	-	2.3.3.13,4.1.3.39,4.1.3.43	ko:K01649,ko:K01666,ko:K18365	ko00290,ko00360,ko00362,ko00620,ko00621,ko00622,ko01100,ko01110,ko01120,ko01210,ko01220,ko01230,map00290,map00360,map00362,map00620,map00621,map00622,map01100,map01110,map01120,map01210,map01220,map01230	M00432,M00545,M00569	R00750,R01213,R05298	RC00004,RC00307,RC00371,RC00470,RC00572,RC02754	br01601,br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DmpG_comm,HMGL-like
CMS3_k127_2481795_4	502025.Hoch_6687	4.529e-27	115.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
CMS3_k127_2481795_1	502025.Hoch_4877	1.593e-98	338.0	COG2856@1|root,COG2856@2|Bacteria,1PADA@1224|Proteobacteria,434WD@68525|delta/epsilon subdivisions,2WZ7C@28221|Deltaproteobacteria,2Z1HG@29|Myxococcales	28221|Deltaproteobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2481795_5	882.DVU_0271	2.883e-07	58.0	COG2204@1|root,COG4192@1|root,COG2204@2|Bacteria,COG4192@2|Bacteria,1R9WW@1224|Proteobacteria,42R68@68525|delta/epsilon subdivisions,2WMSV@28221|Deltaproteobacteria,2M9QN@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
CMS3_k127_2481795_2	1042375.AFPL01000004_gene630	4.372e-34	147.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,1S39E@1236|Gammaproteobacteria,46837@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG2716 Glycine cleavage system regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_4,ACT_6
CMS3_k127_2481795_3	1297742.A176_02032	5.008e-29	133.0	COG0402@1|root,COG1506@1|root,COG2885@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,COG2885@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_2481795_0	502025.Hoch_4876	1.111e-249	788.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2YUID@29|Myxococcales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS3_k127_2504293_2	502025.Hoch_5439	3.297e-185	594.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WTNN@28221|Deltaproteobacteria,2Z35N@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_2504293_8	1294143.H681_07480	0.000607	52.0	2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,1SF2N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS3_k127_2504293_4	502025.Hoch_5656	4.295e-171	561.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2Z340@29|Myxococcales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_2504293_6	391612.CY0110_22147	7.499e-68	237.0	COG1131@1|root,COG1131@2|Bacteria,1G11U@1117|Cyanobacteria,3KFZG@43988|Cyanothece	1117|Cyanobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2504293_1	502025.Hoch_5658	3.655e-226	724.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1R91W@1224|Proteobacteria,42PXP@68525|delta/epsilon subdivisions,2WJJX@28221|Deltaproteobacteria,2YX85@29|Myxococcales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_9
CMS3_k127_2504293_5	502025.Hoch_5659	2.779e-119	398.0	COG0457@1|root,COG3824@1|root,COG0457@2|Bacteria,COG3824@2|Bacteria,1Q3EP@1224|Proteobacteria,43408@68525|delta/epsilon subdivisions,2X4D7@28221|Deltaproteobacteria,2YYSR@29|Myxococcales	28221|Deltaproteobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,Zincin_1
CMS3_k127_2504293_0	502025.Hoch_4612	8.705e-290	915.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2YXGJ@29|Myxococcales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS3_k127_2504293_3	502025.Hoch_4611	1.559e-181	588.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS3_k127_250537_6	502025.Hoch_3287	3.087e-74	252.0	COG1757@1|root,COG1757@2|Bacteria,1MY5C@1224|Proteobacteria,42P0P@68525|delta/epsilon subdivisions,2WN1R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
CMS3_k127_250537_1	502025.Hoch_4214	2.794e-231	725.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2YUG2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
CMS3_k127_250537_5	1121920.AUAU01000004_gene777	1.21e-79	277.0	COG0492@1|root,COG0492@2|Bacteria,3Y2NX@57723|Acidobacteria	57723|Acidobacteria	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
CMS3_k127_250537_4	502025.Hoch_4211	1.556e-89	320.0	COG0438@1|root,COG0438@2|Bacteria,1R0NE@1224|Proteobacteria,42TFU@68525|delta/epsilon subdivisions,2X879@28221|Deltaproteobacteria,2Z1TP@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_250537_10	502025.Hoch_4210	2.117e-50	198.0	COG2120@1|root,COG2120@2|Bacteria,1N9CC@1224|Proteobacteria	1224|Proteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_250537_8	502025.Hoch_4209	6.473e-61	236.0	COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,434T9@68525|delta/epsilon subdivisions,2WZ49@28221|Deltaproteobacteria,2Z1AM@29|Myxococcales	28221|Deltaproteobacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CMS3_k127_250537_9	502025.Hoch_3767	1.177e-60	231.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2YV8J@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS3_k127_250537_0	502025.Hoch_3155	3.429e-276	875.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2YU3A@29|Myxococcales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
CMS3_k127_250537_7	502025.Hoch_3152	1.198e-68	256.0	COG0664@1|root,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YXD4@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_250537_14	243231.GSU3318	2.492e-26	124.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS3_k127_250537_3	502025.Hoch_3151	1.656e-90	334.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2YTWZ@29|Myxococcales	28221|Deltaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS3_k127_250537_2	502025.Hoch_3150	7.364e-177	568.0	COG2937@1|root,COG2937@2|Bacteria,1Q0Y9@1224|Proteobacteria,43F06@68525|delta/epsilon subdivisions,2X2TW@28221|Deltaproteobacteria,2Z2IH@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_250537_12	1242864.D187_004950	1.324e-43	166.0	COG4894@1|root,COG4894@2|Bacteria,1RKPJ@1224|Proteobacteria,434XW@68525|delta/epsilon subdivisions,2WZ8Q@28221|Deltaproteobacteria,2Z1KE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_250537_11	502025.Hoch_3149	8.231e-45	173.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YWIW@29|Myxococcales	28221|Deltaproteobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CMS3_k127_2513962_2	880072.Desac_2671	2.968e-45	183.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS3_k127_2513962_4	216142.LT40_12060	4.915e-25	119.0	COG0601@1|root,COG0601@2|Bacteria,1MUMR@1224|Proteobacteria,1RXXQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter (permease)	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_2513962_3	1051632.TPY_2439	1.008e-31	138.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_2513962_7	742743.HMPREF9453_02063	4.939e-06	59.0	COG1376@1|root,COG1376@2|Bacteria,1TQAB@1239|Firmicutes,4H267@909932|Negativicutes	909932|Negativicutes	S	ErfK YbiS YcfS YnhG	erfK	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,YkuD
CMS3_k127_2513962_0	331869.BAL199_25574	1.075e-99	338.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,4BQ0F@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2513962_5	448385.sce1531	9.678e-14	80.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	LRR_4,LRR_8
CMS3_k127_2513962_1	246197.MXAN_5379	1.13e-90	304.0	COG3833@1|root,COG3833@2|Bacteria,1QXV4@1224|Proteobacteria,43C7S@68525|delta/epsilon subdivisions,2X7I4@28221|Deltaproteobacteria,2Z3GP@29|Myxococcales	28221|Deltaproteobacteria	P	Sugar ABC transporter permease	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
CMS3_k127_251432_2	1123320.KB889585_gene1920	7.513e-111	368.0	COG1024@1|root,COG1024@2|Bacteria,2GN54@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA20	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_251432_3	1240350.AMZE01000075_gene4401	9.819e-92	308.0	COG1028@1|root,COG1028@2|Bacteria,1P1U4@1224|Proteobacteria,1RR3M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_251432_0	502025.Hoch_0058	2.275e-124	420.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria	1224|Proteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_251432_1	309801.trd_A0899	9.612e-112	376.0	COG1060@1|root,COG1060@2|Bacteria,2GBD4@200795|Chloroflexi,27YV4@189775|Thermomicrobia	189775|Thermomicrobia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_2516411_0	1082933.MEA186_30901	0.0	1892.0	COG1572@1|root,COG2931@1|root,COG3210@1|root,COG4070@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4070@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin-like,Calx-beta,DUF4347,He_PIG
CMS3_k127_252961_0	502025.Hoch_6661	4.687e-200	637.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,2YTY5@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
CMS3_k127_252961_3	502025.Hoch_6662	9.107e-71	253.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,43AAM@68525|delta/epsilon subdivisions,2WZ5P@28221|Deltaproteobacteria,2Z1DS@29|Myxococcales	28221|Deltaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS3_k127_252961_6	502025.Hoch_5446	6.388e-29	132.0	COG1366@1|root,COG1366@2|Bacteria,1NG3I@1224|Proteobacteria,42W69@68525|delta/epsilon subdivisions,2WS39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_252961_1	502025.Hoch_6343	9.557e-116	409.0	COG2204@1|root,COG2204@2|Bacteria,1R0E3@1224|Proteobacteria,43CWJ@68525|delta/epsilon subdivisions,2WSIM@28221|Deltaproteobacteria,2YW6V@29|Myxococcales	2|Bacteria	T	response regulator	cpaE	-	2.7.13.3	ko:K02282,ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022,ko02035,ko02044	-	-	-	HATPase_c,HTH_18,HisKA,Response_reg
CMS3_k127_252961_7	926562.Oweho_3532	6.917e-22	113.0	COG3437@1|root,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,1I9RX@117743|Flavobacteriia	976|Bacteroidetes	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
CMS3_k127_252961_5	246197.MXAN_5366	3.447e-29	137.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M3W@68525|delta/epsilon subdivisions,2WNA3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS3_k127_252961_4	644282.Deba_0503	3.342e-53	216.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2WK3K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
CMS3_k127_252961_2	502025.Hoch_6344	4.218e-115	374.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2YXJE@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_2537076_8	477184.KYC_15432	6.675e-10	66.0	COG1566@1|root,COG1566@2|Bacteria,1QUDS@1224|Proteobacteria,2WHE9@28216|Betaproteobacteria,3T73T@506|Alcaligenaceae	28216|Betaproteobacteria	V	COG0845 Membrane-fusion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS3_k127_2537076_1	502025.Hoch_0435	1.07e-205	649.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2537076_4	502025.Hoch_0352	2.243e-60	230.0	COG3266@1|root,COG3266@2|Bacteria,1Q2HB@1224|Proteobacteria,43840@68525|delta/epsilon subdivisions,2X9WR@28221|Deltaproteobacteria,2YVMS@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2537076_9	869210.Marky_1325	4.744e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1WIGW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CMS3_k127_2537076_0	502025.Hoch_0351	2.182e-211	669.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS3_k127_2537076_7	502025.Hoch_5298	7.906e-32	145.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2Z1V2@29|Myxococcales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_2537076_5	502025.Hoch_5300	2.833e-56	201.0	COG0008@1|root,COG0008@2|Bacteria	2|Bacteria	J	glutamate-tRNA ligase activity	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS3_k127_2537076_3	404589.Anae109_1110	4.032e-80	286.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YV0J@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
CMS3_k127_2537559_16	345341.KUTG_02564	0.000509	53.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,GerE,HTH_31,NB-ARC,TPR_10,TPR_12,Trans_reg_C
CMS3_k127_2537559_4	502025.Hoch_5933	1.451e-102	357.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
CMS3_k127_2537559_1	502025.Hoch_5932	1.041e-197	618.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_2537559_5	502025.Hoch_5931	8.942e-102	339.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2YVI1@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS3_k127_2537559_0	502025.Hoch_5929	1.39e-253	796.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2YU5Y@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
CMS3_k127_2537559_3	502025.Hoch_5928	3.977e-129	426.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2YUT8@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS3_k127_2537559_11	404589.Anae109_1372	1.79e-44	169.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2YVHU@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_2537559_15	502025.Hoch_6797	4.641e-26	111.0	2A21P@1|root,30QBQ@2|Bacteria,1Q2MF@1224|Proteobacteria,43882@68525|delta/epsilon subdivisions,2X3HT@28221|Deltaproteobacteria,2YW5S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2537559_9	502025.Hoch_6798	2.946e-86	293.0	COG4137@1|root,COG4137@2|Bacteria,1R3M0@1224|Proteobacteria,43DKU@68525|delta/epsilon subdivisions,2X8S0@28221|Deltaproteobacteria,2YW4U@29|Myxococcales	28221|Deltaproteobacteria	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS3_k127_2537559_2	502025.Hoch_6799	6.682e-155	501.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2YU5J@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_2537559_6	1117647.M5M_11790	3.415e-94	336.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1J4EA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849	Porphobil_deam,Porphobil_deamC
CMS3_k127_2537559_14	1227487.C474_03200	6.291e-30	130.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_2537559_12	502025.Hoch_0500	5.584e-39	156.0	COG1729@1|root,COG1729@2|Bacteria,1PRB4@1224|Proteobacteria,42UBY@68525|delta/epsilon subdivisions,2WQMR@28221|Deltaproteobacteria,2YVZE@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
CMS3_k127_2537559_7	502025.Hoch_0501	2.295e-93	320.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2YVFR@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_2537559_10	290397.Adeh_2700	1.487e-48	184.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2YVFF@29|Myxococcales	28221|Deltaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
CMS3_k127_2537559_8	502025.Hoch_4636	1.241e-91	323.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
CMS3_k127_2571656_3	502025.Hoch_6871	1.265e-57	205.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria,2YVEI@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
CMS3_k127_2571656_7	1122164.JHWF01000022_gene1733	0.0001461	47.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2571656_1	483219.LILAB_17510	1.612e-150	487.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2YWV6@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
CMS3_k127_2571656_4	765869.BDW_02565	4.359e-35	141.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2MUR4@213481|Bdellovibrionales,2WQA9@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2571656_6	1519464.HY22_04455	1.303e-05	57.0	2A7N9@1|root,30WKB@2|Bacteria,1FFFR@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2571656_0	502025.Hoch_6872	1.762e-156	542.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2YVS5@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
CMS3_k127_2571656_2	1254432.SCE1572_34855	3.675e-120	406.0	COG0318@1|root,COG0318@2|Bacteria,1PG0N@1224|Proteobacteria,42ZGH@68525|delta/epsilon subdivisions,2WUZC@28221|Deltaproteobacteria,2YXZH@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2573119_1	502025.Hoch_3761	2.033e-105	364.0	COG1233@1|root,COG1233@2|Bacteria,1Q2HN@1224|Proteobacteria,4384H@68525|delta/epsilon subdivisions,2X3EF@28221|Deltaproteobacteria,2YVQ0@29|Myxococcales	28221|Deltaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
CMS3_k127_2573119_3	502025.Hoch_3760	1.812e-62	235.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2YVC1@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS3_k127_2573119_0	502025.Hoch_3759	3.073e-121	398.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2YTTG@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
CMS3_k127_2573119_4	502025.Hoch_3758	2.626e-55	201.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF2064,Glycos_transf_2
CMS3_k127_2573119_5	290397.Adeh_1256	1.64e-51	190.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria,2YVRK@29|Myxococcales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
CMS3_k127_2573119_6	502025.Hoch_3757	4.216e-34	138.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GGDEF,HTH_18,HTH_8,HisKA,Response_reg
CMS3_k127_2573119_2	502025.Hoch_3756	8.19e-70	241.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,2YU1S@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_2588439_2	502025.Hoch_6539	6.869e-23	104.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2588439_0	215803.DB30_8367	2.608e-147	483.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,4345U@68525|delta/epsilon subdivisions,2X20T@28221|Deltaproteobacteria,2YVEZ@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS
CMS3_k127_2588439_1	234267.Acid_4168	7.265e-33	130.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2614410_0	448385.sce8071	5.354e-22	104.0	COG2133@1|root,COG4932@1|root,COG5624@1|root,COG2133@2|Bacteria,COG4932@2|Bacteria,COG5624@2|Bacteria,1QUEG@1224|Proteobacteria,42YJZ@68525|delta/epsilon subdivisions,2WWPU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KM	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B,TGFb_propeptide
CMS3_k127_2614410_1	1121899.Q764_13640	7.434e-06	53.0	2DSXX@1|root,33HVY@2|Bacteria,4NY8M@976|Bacteroidetes,1IAEE@117743|Flavobacteriia,2NXQQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2614427_1	502025.Hoch_6663	9.192e-113	374.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2614427_4	1210884.HG799462_gene7813	9.395e-30	136.0	COG2453@1|root,COG2453@2|Bacteria,2J01Y@203682|Planctomycetes	203682|Planctomycetes	T	Protein-tyrosine phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc
CMS3_k127_2614427_2	502025.Hoch_3733	1.473e-43	177.0	COG5036@1|root,COG5036@2|Bacteria,1Q2HG@1224|Proteobacteria,43849@68525|delta/epsilon subdivisions,2X3E5@28221|Deltaproteobacteria,2YVNM@29|Myxococcales	28221|Deltaproteobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS3_k127_2614427_5	215803.DB30_0686	9.041e-29	135.0	2AIUN@1|root,319BU@2|Bacteria,1Q29W@1224|Proteobacteria,437WR@68525|delta/epsilon subdivisions,2X36D@28221|Deltaproteobacteria,2YUHX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2614427_0	1254432.SCE1572_45180	2.735e-212	702.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria,4340K@68525|delta/epsilon subdivisions,2X4FG@28221|Deltaproteobacteria,2YYX6@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
CMS3_k127_2614427_6	1211114.ALIP01000004_gene1190	5.955e-12	77.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,1S111@1236|Gammaproteobacteria,1XCC2@135614|Xanthomonadales	135614|Xanthomonadales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS3_k127_2614427_3	502025.Hoch_5230	3.337e-38	150.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	Peptidase_C39,Peptidase_C70
CMS3_k127_2615575_14	326442.PSHAa1456	5.047e-39	159.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,2Q178@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	acdA	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2615575_10	1051632.TPY_1634	1.651e-72	271.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2615575_7	479434.Sthe_0714	4.956e-124	415.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,27Y4Z@189775|Thermomicrobia	189775|Thermomicrobia	O	MreB/Mbl protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_2615575_20	272134.KB731324_gene5231	9.395e-05	55.0	COG0484@1|root,COG0484@2|Bacteria,1G2FB@1117|Cyanobacteria,1H7JY@1150|Oscillatoriales	1117|Cyanobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
CMS3_k127_2615575_5	502025.Hoch_0130	5.048e-149	481.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,43A1E@68525|delta/epsilon subdivisions,2X9Q3@28221|Deltaproteobacteria,2YZN3@29|Myxococcales	28221|Deltaproteobacteria	I	Chalcone and stilbene synthases, N-terminal domain	-	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_2615575_0	502025.Hoch_0129	4.645e-269	844.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,42NR5@68525|delta/epsilon subdivisions,2WMMK@28221|Deltaproteobacteria,2YU26@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_2615575_2	448385.sce8590	1.914e-255	823.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,42NR5@68525|delta/epsilon subdivisions,2WMMK@28221|Deltaproteobacteria,2YU26@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	pep	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_2615575_4	502025.Hoch_0127	9.166e-150	480.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2YTUG@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K12371,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00324,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_2615575_6	502025.Hoch_0126	4.469e-134	451.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU5K@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_2615575_1	502025.Hoch_0125	2.91e-259	837.0	COG0457@1|root,COG0784@1|root,COG1074@1|root,COG0457@2|Bacteria,COG0784@2|Bacteria,COG1074@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	1224|Proteobacteria	G	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,Peptidase_C14,TPR_1,TPR_16,TPR_2,TPR_8
CMS3_k127_2615575_3	502025.Hoch_0124	2.625e-207	652.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YTZB@29|Myxococcales	28221|Deltaproteobacteria	E	synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_2615575_17	502025.Hoch_1884	7.249e-30	121.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,43APU@68525|delta/epsilon subdivisions,2X63M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_2615575_19	502025.Hoch_1884	9.382e-11	71.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,43APU@68525|delta/epsilon subdivisions,2X63M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_2615575_16	502025.Hoch_0144	1.844e-33	133.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
CMS3_k127_2615575_9	502025.Hoch_0145	2.122e-78	266.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YVKS@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2615575_11	502025.Hoch_0146	1.09e-69	246.0	2AGT8@1|root,3171A@2|Bacteria,1PY9M@1224|Proteobacteria,4356T@68525|delta/epsilon subdivisions,2WZHY@28221|Deltaproteobacteria,2Z26Q@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2615575_13	502025.Hoch_0147	1.625e-59	220.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2YVFT@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS3_k127_2615575_15	1123368.AUIS01000011_gene1183	9.925e-36	150.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2615575_12	290397.Adeh_1074	6.522e-61	218.0	COG0515@1|root,COG2214@1|root,COG0515@2|Bacteria,COG2214@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria,2YXDF@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
CMS3_k127_2629897_3	448385.sce1637	1.481e-36	142.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,43A4M@68525|delta/epsilon subdivisions,2WYKE@28221|Deltaproteobacteria,2Z0NN@29|Myxococcales	1224|Proteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_2629897_1	1173028.ANKO01000147_gene1272	1.82e-91	316.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.7	ko:K02342,ko:K02660	ko00230,ko00240,ko01100,ko02020,ko02025,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map02025,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044,ko03032,ko03400	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,MASE1,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS3_k127_2629897_0	448385.sce6858	4.434e-111	389.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,438M3@68525|delta/epsilon subdivisions,2X1ZS@28221|Deltaproteobacteria,2YX8A@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
CMS3_k127_2629897_2	1192034.CAP_3825	2.135e-69	269.0	29ZQ8@1|root,30MQZ@2|Bacteria,1QB4G@1224|Proteobacteria,435E7@68525|delta/epsilon subdivisions,2WZRU@28221|Deltaproteobacteria,2Z2M5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_2629897_4	1120963.KB894492_gene1688	2.911e-32	134.0	COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,1SA53@1236|Gammaproteobacteria,2Q3TJ@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N_3
CMS3_k127_264222_0	502025.Hoch_6714	0.0	1820.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS3_k127_264222_1	502025.Hoch_6713	1.59e-190	632.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
CMS3_k127_264222_2	1192034.CAP_4236	6.544e-23	116.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_266200_36	66373.JOFQ01000035_gene2797	4.038e-22	111.0	COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria	201174|Actinobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
CMS3_k127_266200_31	1223523.H340_24105	1.842e-34	139.0	COG1309@1|root,COG1309@2|Bacteria,2GJPK@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_C_6,TetR_N
CMS3_k127_266200_21	563040.Saut_0928	5.6e-61	239.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2YR2T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_266200_24	1191299.AJYX01000096_gene1957	4.996e-48	183.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XVD7@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_266200_44	1419583.V466_25625	4.452e-07	62.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1YUB8@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_266200_19	378806.STAUR_4285	4.917e-68	256.0	COG2960@1|root,COG2960@2|Bacteria,1R494@1224|Proteobacteria,43CJP@68525|delta/epsilon subdivisions,2X7U1@28221|Deltaproteobacteria,2YXZK@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_266200_10	1254432.SCE1572_24230	3.117e-113	388.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,430JB@68525|delta/epsilon subdivisions,2WVTU@28221|Deltaproteobacteria,2YWQ0@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_266200_49	691883.XP_009497628.1	0.000631	52.0	COG1404@1|root,KOG3525@2759|Eukaryota	2759|Eukaryota	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Furin-like_2,GF_recep_IV,Pkinase
CMS3_k127_266200_42	768670.Calni_0340	1.441e-13	83.0	COG2067@1|root,COG2067@2|Bacteria,2GFPR@200930|Deferribacteres	200930|Deferribacteres	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_266200_16	1192034.CAP_3825	4.877e-79	279.0	29ZQ8@1|root,30MQZ@2|Bacteria,1QB4G@1224|Proteobacteria,435E7@68525|delta/epsilon subdivisions,2WZRU@28221|Deltaproteobacteria,2Z2M5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_266200_40	448385.sce5929	5.093e-14	86.0	2DSD6@1|root,33FM0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_266200_18	502025.Hoch_2607	5.227e-71	252.0	COG3031@1|root,COG3031@2|Bacteria,1NB50@1224|Proteobacteria,42WPG@68525|delta/epsilon subdivisions,2WREX@28221|Deltaproteobacteria,2YVJ9@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CMS3_k127_266200_33	443144.GM21_3583	2.71e-25	111.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS3_k127_266200_11	518766.Rmar_1656	1.68e-107	365.0	COG0019@1|root,COG0527@1|root,COG0019@2|Bacteria,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,1FIKN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	2.7.2.4,4.1.1.20	ko:K00928,ko:K12526	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00451,R00480	RC00002,RC00043,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS3_k127_266200_30	1123367.C666_07555	1.193e-35	144.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,2VW3B@28216|Betaproteobacteria	28216|Betaproteobacteria	K	L-2,4-diaminobutyric acid acetyltransferase	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_266200_7	702113.PP1Y_AT4598	4.206e-157	514.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TR8I@28211|Alphaproteobacteria,2K2N9@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_266200_28	1121090.KB894694_gene2159	3.52e-41	174.0	COG1917@1|root,COG1917@2|Bacteria,1V719@1239|Firmicutes,4HIPQ@91061|Bacilli,1ZGMT@1386|Bacillus	91061|Bacilli	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
CMS3_k127_266200_12	1120705.FG95_03435	1.149e-97	333.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2U0FP@28211|Alphaproteobacteria,2K3KD@204457|Sphingomonadales	204457|Sphingomonadales	Q	Multidrug DMT transporter permease	-	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS3_k127_266200_8	756272.Plabr_3299	1.416e-149	498.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
CMS3_k127_266200_29	756272.Plabr_3304	1.096e-35	141.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	mgrA	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS3_k127_266200_39	182217.HCW_03645	3.498e-16	84.0	COG0789@1|root,COG0789@2|Bacteria,1N948@1224|Proteobacteria,42SGY@68525|delta/epsilon subdivisions,2YPH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Transcriptional regulator	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
CMS3_k127_266200_1	502025.Hoch_5561	5.944e-257	816.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,42V1G@68525|delta/epsilon subdivisions,2WRCZ@28221|Deltaproteobacteria,2YWCA@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_266200_17	502025.Hoch_6393	6.858e-74	283.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_266200_23	575540.Isop_3045	2.586e-51	188.0	COG0457@1|root,COG0457@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_266200_4	502025.Hoch_2284	2.018e-195	634.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,43AH9@68525|delta/epsilon subdivisions,2X5XB@28221|Deltaproteobacteria,2Z37F@29|Myxococcales	28221|Deltaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_266200_6	349521.HCH_06289	2.2e-159	514.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1XNGP@135619|Oceanospirillales	135619|Oceanospirillales	E	Creatinase/Prolidase N-terminal domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.4.13.9,3.5.4.44	ko:K01271,ko:K15783	ko00260,ko01100,map00260,map01100	-	R09800	RC02661	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_266200_14	1120936.KB907221_gene2218	9.85e-91	310.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4EH4V@85012|Streptosporangiales	201174|Actinobacteria	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_266200_3	502025.Hoch_2286	6.857e-224	716.0	COG0696@1|root,COG3379@1|root,COG0696@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,43DP4@68525|delta/epsilon subdivisions,2X6QC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_266200_0	502025.Hoch_2285	2.502e-318	988.0	COG0696@1|root,COG3379@1|root,COG0696@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42PUB@68525|delta/epsilon subdivisions,2WMH5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_266200_2	502025.Hoch_2284	1.54e-250	799.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,43AH9@68525|delta/epsilon subdivisions,2X5XB@28221|Deltaproteobacteria,2Z37F@29|Myxococcales	28221|Deltaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_266200_27	1507.HMPREF0262_01999	2.008e-42	180.0	COG4692@1|root,COG4692@2|Bacteria,1UJSZ@1239|Firmicutes,25AZC@186801|Clostridia	186801|Clostridia	G	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS3_k127_266200_47	398578.Daci_5865	0.0001408	50.0	COG1633@1|root,COG3861@1|root,COG1633@2|Bacteria,COG3861@2|Bacteria,1RGZG@1224|Proteobacteria,2VSVM@28216|Betaproteobacteria,4ABHC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
CMS3_k127_266200_26	502025.Hoch_0327	2.059e-43	171.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_266200_25	1242864.D187_002368	2.05e-46	183.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,43BGZ@68525|delta/epsilon subdivisions,2X6V9@28221|Deltaproteobacteria,2YWSQ@29|Myxococcales	28221|Deltaproteobacteria	P	Ferritin-like domain	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS3_k127_266200_35	502025.Hoch_5007	3.097e-22	109.0	COG0589@1|root,COG0589@2|Bacteria,1NN89@1224|Proteobacteria,434TG@68525|delta/epsilon subdivisions,2WZ4G@28221|Deltaproteobacteria,2Z1B6@29|Myxococcales	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_266200_9	1246995.AFR_16910	9.4e-124	416.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_266200_34	483219.LILAB_04025	3.729e-24	106.0	COG0745@1|root,COG0745@2|Bacteria,1MZ7D@1224|Proteobacteria,42VVV@68525|delta/epsilon subdivisions,2WRBW@28221|Deltaproteobacteria,2YVNP@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_266200_5	1254432.SCE1572_50055	2.258e-161	543.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z2X4@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_266200_15	448385.sce7800	5.7e-86	317.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AQK@68525|delta/epsilon subdivisions,2X64H@28221|Deltaproteobacteria,2Z00K@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_266200_38	502025.Hoch_6657	1.732e-16	94.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_266200_45	1266925.JHVX01000004_gene1199	1.299e-05	56.0	COG0517@1|root,COG0517@2|Bacteria,1QTWY@1224|Proteobacteria,2VTYW@28216|Betaproteobacteria,373PN@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_266200_46	1458357.BG58_16450	1.54e-05	57.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2VRH6@28216|Betaproteobacteria,1K78S@119060|Burkholderiaceae	28216|Betaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS3_k127_266200_20	502025.Hoch_6359	3.718e-64	234.0	2AF1T@1|root,31507@2|Bacteria,1PUYN@1224|Proteobacteria,43842@68525|delta/epsilon subdivisions,2X3E0@28221|Deltaproteobacteria,2YVMX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_266200_13	1163617.SCD_n00016	5.459e-96	335.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS3_k127_266200_22	118161.KB235922_gene1131	2.713e-55	197.0	COG3837@1|root,COG3837@2|Bacteria,1G4Z5@1117|Cyanobacteria	1117|Cyanobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_266200_41	1112204.GPOL_c00110	9.192e-14	74.0	2DSC0@1|root,33FF9@2|Bacteria,2HB1X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_266200_37	749414.SBI_00092	2.405e-21	101.0	COG0640@1|root,COG0640@2|Bacteria,2H1MC@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_2665443_3	502025.Hoch_3704	1.377e-64	222.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,2YUQJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS3_k127_2665443_2	880073.Calab_1130	1.216e-65	237.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
CMS3_k127_2665443_5	935863.AWZR01000013_gene1524	2.238e-16	95.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X484@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S8 family	-	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,PPC,P_proprotein,Peptidase_S8
CMS3_k127_2665443_4	1192034.CAP_3547	8.404e-21	109.0	COG3210@1|root,COG4786@1|root,COG5184@1|root,COG3210@2|Bacteria,COG4786@2|Bacteria,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_2665443_0	502025.Hoch_5721	1.783e-135	475.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
CMS3_k127_2665443_1	448385.sce4587	3.354e-95	336.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,43C0J@68525|delta/epsilon subdivisions,2X7B7@28221|Deltaproteobacteria,2YUMJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2665908_2	1192034.CAP_3089	4.654e-53	200.0	COG0402@1|root,COG2374@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria,2YUGP@29|Myxococcales	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,DUF4215,LTD,TSP_3
CMS3_k127_2665908_0	246197.MXAN_5178	2.461e-94	319.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42R8B@68525|delta/epsilon subdivisions,2X5KI@28221|Deltaproteobacteria,2YUUJ@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS3_k127_2665908_8	448385.sce0201	2.782e-20	104.0	COG5640@1|root,COG5640@2|Bacteria,1Q1VE@1224|Proteobacteria,432CB@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_2665908_5	290397.Adeh_2856	6.882e-38	153.0	COG0558@1|root,COG0558@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria,2YWYE@29|Myxococcales	28221|Deltaproteobacteria	I	GtrA-like protein	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,GtrA
CMS3_k127_2665908_6	713586.KB900536_gene511	1.853e-33	134.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1WY89@135613|Chromatiales	135613|Chromatiales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CMS3_k127_2665908_9	313596.RB2501_04895	5.936e-07	57.0	COG2608@1|root,COG2608@2|Bacteria,4NEDS@976|Bacteroidetes,1HYSS@117743|Flavobacteriia	976|Bacteroidetes	P	mercuric transport protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA,MerT
CMS3_k127_2665908_4	1278073.MYSTI_07641	6.511e-44	176.0	COG4447@1|root,COG4447@2|Bacteria,1QX8J@1224|Proteobacteria,43C1P@68525|delta/epsilon subdivisions,2X7CA@28221|Deltaproteobacteria,2YW1N@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS3_k127_2665908_7	557599.MKAN_01715	3.566e-28	119.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria,23ADW@1762|Mycobacteriaceae	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS3_k127_2665908_3	215803.DB30_6303	3.633e-46	177.0	COG4191@1|root,COG4191@2|Bacteria,1R9SH@1224|Proteobacteria,42QAE@68525|delta/epsilon subdivisions,2WM61@28221|Deltaproteobacteria,2YZ8F@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,dCache_1
CMS3_k127_2665908_10	485918.Cpin_4979	1.509e-05	56.0	COG5492@1|root,COG5492@2|Bacteria,4NT99@976|Bacteroidetes	976|Bacteroidetes	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,CBM9_1,DM13,DUF4979,Pectate_lyase_3
CMS3_k127_2665908_1	502025.Hoch_5616	6.471e-62	218.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,42QMK@68525|delta/epsilon subdivisions,2X5B1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NmrA
CMS3_k127_266919_2	502025.Hoch_5306	1.889e-43	173.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2YVEB@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
CMS3_k127_266919_3	1125863.JAFN01000001_gene1060	6.824e-17	92.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_266919_0	502025.Hoch_1767	2.042e-248	797.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2YUEP@29|Myxococcales	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS3_k127_266919_1	502025.Hoch_5896	1.83e-110	361.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
CMS3_k127_2683199_9	3659.XP_004144712.1	8.049e-05	53.0	KOG4234@1|root,KOG4234@2759|Eukaryota,37PT2@33090|Viridiplantae,3G9QT@35493|Streptophyta,4JMG1@91835|fabids	35493|Streptophyta	S	tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
CMS3_k127_2683199_5	502025.Hoch_6032	1.593e-64	229.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_2683199_1	502025.Hoch_6033	9.577e-101	335.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2YUYQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
CMS3_k127_2683199_0	1125863.JAFN01000001_gene3143	1.168e-126	417.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2WKS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2683199_6	1192034.CAP_7488	1.366e-52	210.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_2683199_8	459349.CLOAM0834	3.392e-05	57.0	COG4676@1|root,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	VWA_3
CMS3_k127_2683199_2	502025.Hoch_6034	5.228e-81	276.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,42TQ7@68525|delta/epsilon subdivisions,2WS2Q@28221|Deltaproteobacteria,2YVF5@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS3_k127_2683199_7	999541.bgla_2g23630	2.317e-50	204.0	COG3842@1|root,COG3842@2|Bacteria,1NYPP@1224|Proteobacteria,2VQ7J@28216|Betaproteobacteria,1K358@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran
CMS3_k127_2683199_4	395963.Bind_2520	1.358e-66	254.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,3NCS4@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS3_k127_2683199_3	247490.KSU1_B0521	2.75e-78	268.0	COG1840@1|root,COG1840@2|Bacteria,2IXGE@203682|Planctomycetes	203682|Planctomycetes	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
CMS3_k127_2710119_3	1144275.COCOR_06625	8.125e-09	68.0	COG3637@1|root,COG3637@2|Bacteria,1Q9QE@1224|Proteobacteria,434IR@68525|delta/epsilon subdivisions,2X8WU@28221|Deltaproteobacteria,2Z0RY@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS3_k127_2710119_1	593750.Metfor_1598	1.048e-15	93.0	COG3291@1|root,COG5276@1|root,arCOG02516@1|root,arCOG02914@1|root,arCOG04005@1|root,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG02565@2157|Archaea,arCOG02914@2157|Archaea,arCOG04005@2157|Archaea	2157|Archaea	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LVIVD,PKD
CMS3_k127_2710119_4	246197.MXAN_3971	0.000961	52.0	COG2374@1|root,COG3568@1|root,COG2374@2|Bacteria,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	XK27_02140	-	3.2.1.4	ko:K01179,ko:K07004	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	5_nucleotid_C,CHB_HEX_C_1,Calx-beta,Exo_endo_phos,Gram_pos_anchor,HemolysinCabind,LTD,Metallophos,SLH
CMS3_k127_2710119_0	502025.Hoch_2608	3.888e-29	119.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_2715026_2	502025.Hoch_4042	3.021e-99	329.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria,2YWYS@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS3_k127_2715026_0	502025.Hoch_5723	2.269e-275	857.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria,2YU4T@29|Myxococcales	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS3_k127_2715026_4	502025.Hoch_0284	1.938e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,1PD3E@1224|Proteobacteria,43E55@68525|delta/epsilon subdivisions,2X98H@28221|Deltaproteobacteria,2Z2M0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2715026_3	502025.Hoch_0285	5.274e-90	321.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
CMS3_k127_2715026_1	502025.Hoch_0286	5.304e-216	699.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2715026_5	1429046.RR21198_3072	1.899e-10	74.0	COG2146@1|root,COG2146@2|Bacteria,2IIR1@201174|Actinobacteria,4G2JK@85025|Nocardiaceae	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
CMS3_k127_273751_2	502025.Hoch_6186	1.391e-186	627.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
CMS3_k127_273751_5	391625.PPSIR1_38751	1.538e-50	190.0	COG0457@1|root,COG0457@2|Bacteria,1QASR@1224|Proteobacteria,4359Y@68525|delta/epsilon subdivisions,2WZM1@28221|Deltaproteobacteria,2Z2CS@29|Myxococcales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
CMS3_k127_273751_0	1303518.CCALI_00290	4.372e-317	1019.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_273751_4	502025.Hoch_5925	3.909e-68	260.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	dnaJ1	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS3_k127_273751_1	502025.Hoch_5926	3.08e-241	783.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	-	-	-	-	-	-	-	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_273751_6	378806.STAUR_3310	1.706e-12	79.0	COG1729@1|root,COG1729@2|Bacteria,1Q3F0@1224|Proteobacteria,42XMM@68525|delta/epsilon subdivisions,2WTBN@28221|Deltaproteobacteria,2YYTS@29|Myxococcales	28221|Deltaproteobacteria	S	B-box zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_275437_0	1380347.JNII01000006_gene1411	4.776e-65	229.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria,4EV8F@85013|Frankiales	201174|Actinobacteria	E	GMC oxidoreductase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
CMS3_k127_275437_2	1242864.D187_008027	1.189e-05	55.0	COG4258@1|root,COG4258@2|Bacteria	2|Bacteria	I	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_2762802_3	502025.Hoch_4730	2.613e-55	205.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07714,ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	M00500	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2762802_4	502025.Hoch_2618	4.574e-54	209.0	2DRH1@1|root,33BQ8@2|Bacteria,1NM8D@1224|Proteobacteria,42XND@68525|delta/epsilon subdivisions,2WSKN@28221|Deltaproteobacteria,2YW71@29|Myxococcales	28221|Deltaproteobacteria	-	-	gspN	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
CMS3_k127_2762802_0	502025.Hoch_2616	9.307e-144	475.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
CMS3_k127_2762802_1	502025.Hoch_2615	5.26e-129	428.0	COG3156@1|root,COG3156@2|Bacteria,1RIW9@1224|Proteobacteria,42V6H@68525|delta/epsilon subdivisions,2X2BW@28221|Deltaproteobacteria,2YVV7@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS3_k127_2762802_2	502025.Hoch_2614	1.755e-57	213.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria,2YVMW@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CMS3_k127_2762802_6	502025.Hoch_2613	4.821e-36	151.0	COG4967@1|root,COG4967@2|Bacteria,1QUS3@1224|Proteobacteria,42X07@68525|delta/epsilon subdivisions,2WSQI@28221|Deltaproteobacteria,2YW2A@29|Myxococcales	28221|Deltaproteobacteria	U	Prokaryotic N-terminal methylation motif	gspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS3_k127_2762802_5	502025.Hoch_2612	1.679e-39	157.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K10927,ko:K12285	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_2762802_8	502025.Hoch_2611	1.531e-24	109.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2YW2T@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_277242_2	644282.Deba_3041	9.426e-99	330.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
CMS3_k127_277242_1	502025.Hoch_2506	8.353e-194	627.0	COG0463@1|root,COG1621@1|root,COG0463@2|Bacteria,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Big_2,Galactosyl_T,Glyco_hydro_32N,Glyco_hydro_43,Glyco_tranf_2_4,Glyco_transf_92,SLH
CMS3_k127_277242_0	502025.Hoch_2507	1.512e-257	807.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_2787909_12	502025.Hoch_0284	1.303e-15	86.0	COG1595@1|root,COG1595@2|Bacteria,1PD3E@1224|Proteobacteria,43E55@68525|delta/epsilon subdivisions,2X98H@28221|Deltaproteobacteria,2Z2M0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2787909_13	713586.KB900536_gene2173	5.12e-10	64.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WWTP@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K10126,ko:K10943	ko02020,ko05111,map02020,map05111	M00504,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2787909_14	487521.OCU_08460	2.514e-07	55.0	COG2906@1|root,2ZWI0@2|Bacteria,2I4ET@201174|Actinobacteria,23B6K@1762|Mycobacteriaceae	201174|Actinobacteria	P	2Fe-2S -binding domain	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
CMS3_k127_2787909_9	502025.Hoch_6396	1.209e-41	168.0	2DBMC@1|root,2Z9YC@2|Bacteria,1PY40@1224|Proteobacteria,43E0Z@68525|delta/epsilon subdivisions,2WZDV@28221|Deltaproteobacteria,2Z1X8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2787909_1	879212.DespoDRAFT_00920	2.674e-128	427.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WJX5@28221|Deltaproteobacteria,2MHX3@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS3_k127_2787909_6	378806.STAUR_7238	1.713e-101	367.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2787909_4	378806.STAUR_7238	6.31e-111	377.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2787909_5	378806.STAUR_7238	3.45e-102	352.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2787909_8	1177181.T9A_00193	2.122e-53	201.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,1S1Y5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_2787909_0	448385.sce3262	3.275e-158	514.0	COG5337@1|root,COG5337@2|Bacteria,1PBM0@1224|Proteobacteria,437W6@68525|delta/epsilon subdivisions,2X35Q@28221|Deltaproteobacteria,2YUDH@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_2787909_10	1158292.JPOE01000002_gene3045	1.019e-35	143.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ6F@28216|Betaproteobacteria,1KKPY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_2787909_3	861299.J421_5728	1.933e-117	400.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_2787909_16	604331.AUHY01000007_gene713	3.024e-05	57.0	COG3895@1|root,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
CMS3_k127_2787909_11	1122604.JONR01000035_gene371	7.502e-30	130.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,1T08P@1236|Gammaproteobacteria,1X6V6@135614|Xanthomonadales	135614|Xanthomonadales	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_2787909_17	502025.Hoch_2411	0.0001486	52.0	2BB4A@1|root,324KN@2|Bacteria,1QAPV@1224|Proteobacteria,4357V@68525|delta/epsilon subdivisions,2X96M@28221|Deltaproteobacteria,2Z28J@29|Myxococcales	502025.Hoch_2411|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2787909_7	215803.DB30_0443	3.378e-73	261.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WUVK@28221|Deltaproteobacteria,2YYXR@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
CMS3_k127_2787909_2	215803.DB30_6384	6.809e-124	426.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
CMS3_k127_2873704_11	502025.Hoch_3744	1.166e-57	202.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2YWE0@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
CMS3_k127_2873704_1	502025.Hoch_3743	1.235e-160	525.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS3_k127_2873704_4	502025.Hoch_3743	2.567e-97	328.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS3_k127_2873704_13	502025.Hoch_3742	6.189e-50	179.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,2YVCZ@29|Myxococcales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_2873704_15	502025.Hoch_3741	1.721e-32	129.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_2873704_5	502025.Hoch_3740	1.699e-74	259.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2YVC8@29|Myxococcales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS3_k127_2873704_12	667014.Thein_1148	4.444e-53	199.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_2873704_9	502025.Hoch_3739	2.889e-61	216.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2Z0FU@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS3_k127_2873704_6	404589.Anae109_4131	4.56e-71	248.0	28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria	1224|Proteobacteria	S	PFAM RES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RES
CMS3_k127_2873704_16	1278073.MYSTI_04193	6.019e-31	138.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PD6@68525|delta/epsilon subdivisions,2WK6G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_2873704_18	448385.sce6248	1.952e-20	98.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria,2YVV1@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS3_k127_2873704_2	502025.Hoch_5171	2.2e-139	462.0	COG4775@1|root,COG4775@2|Bacteria,1Q2CZ@1224|Proteobacteria,437ZA@68525|delta/epsilon subdivisions,2X399@28221|Deltaproteobacteria,2YUX9@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_2873704_25	404380.Gbem_3899	2.139e-05	55.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS3_k127_2873704_24	754476.Q7A_2045	3.084e-09	68.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,4603D@72273|Thiotrichales	72273|Thiotrichales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_2873704_22	1508644.SFBmNL_00632	3.129e-17	91.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,36I0M@31979|Clostridiaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
CMS3_k127_2873704_19	138119.DSY1288	5.556e-20	102.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_2873704_3	404589.Anae109_4286	2.742e-104	374.0	COG4258@1|root,COG4258@2|Bacteria,1QX7Z@1224|Proteobacteria,43C13@68525|delta/epsilon subdivisions,2X7BR@28221|Deltaproteobacteria,2YU55@29|Myxococcales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_2873704_21	335543.Sfum_2920	2.851e-17	95.0	COG0558@1|root,COG0558@2|Bacteria,1PDPE@1224|Proteobacteria,42XWH@68525|delta/epsilon subdivisions,2X38Z@28221|Deltaproteobacteria,2MSFQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_2873704_8	502025.Hoch_1883	8.015e-65	231.0	2APYA@1|root,31F34@2|Bacteria,1QCGE@1224|Proteobacteria,435JY@68525|delta/epsilon subdivisions,2WZY6@28221|Deltaproteobacteria,2Z108@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2873704_20	502025.Hoch_1882	7.999e-18	99.0	2BT96@1|root,32NEJ@2|Bacteria,1QANP@1224|Proteobacteria,43573@68525|delta/epsilon subdivisions,2WZI4@28221|Deltaproteobacteria,2Z275@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2873704_0	1254432.SCE1572_45120	1.062e-170	571.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_2873704_23	459495.SPLC1_S361270	2.945e-15	91.0	COG0664@1|root,COG0664@2|Bacteria,1G57E@1117|Cyanobacteria,1HAIX@1150|Oscillatoriales	1117|Cyanobacteria	T	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_2873704_7	1469607.KK073768_gene1550	4.964e-66	255.0	COG0348@1|root,COG0664@1|root,COG0348@2|Bacteria,COG0664@2|Bacteria,1FZVX@1117|Cyanobacteria,1HKSY@1161|Nostocales	1117|Cyanobacteria	C	cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Fer4_5,cNMP_binding
CMS3_k127_2873704_17	1499967.BAYZ01000016_gene6535	8.199e-23	112.0	COG4447@1|root,COG4447@2|Bacteria,2NQ80@2323|unclassified Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
CMS3_k127_2873704_14	1123278.KB893615_gene5179	2.56e-44	183.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_2873704_10	656024.FsymDg_2976	3.957e-60	229.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2GMPZ@201174|Actinobacteria,4ESG4@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NHL,Pkinase
CMS3_k127_2873704_27	1122599.AUGR01000009_gene2482	0.0003092	53.0	2EVNQ@1|root,33P2R@2|Bacteria	2|Bacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
CMS3_k127_2873704_26	160860.XP_007347783.1	6.489e-05	55.0	COG2340@1|root,KOG3017@2759|Eukaryota,3A9R7@33154|Opisthokonta,3P7QX@4751|Fungi,3VAHF@5204|Basidiomycota,22C4X@155619|Agaricomycetes,3H7BB@355688|Agaricomycetes incertae sedis	4751|Fungi	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_2879995_2	502025.Hoch_5445	4.212e-80	271.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,GGDEF,HATPase_c,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1
CMS3_k127_2879995_1	502025.Hoch_5444	2.605e-112	370.0	COG1366@1|root,COG1366@2|Bacteria,1NG3I@1224|Proteobacteria,42W69@68525|delta/epsilon subdivisions,2WS39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2879995_0	502025.Hoch_5443	0.0	1429.0	COG0457@1|root,COG0457@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_7,TPR_8
CMS3_k127_2883498_10	1173028.ANKO01000065_gene5619	1.579e-20	108.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,1H919@1150|Oscillatoriales	1117|Cyanobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
CMS3_k127_2883498_2	502025.Hoch_0085	9.046e-93	341.0	COG0492@1|root,COG1146@1|root,COG3266@1|root,COG0492@2|Bacteria,COG1146@2|Bacteria,COG3266@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
CMS3_k127_2883498_0	886293.Sinac_1156	1.724e-211	702.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2883498_7	502025.Hoch_1850	1.214e-59	224.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42R3E@68525|delta/epsilon subdivisions,2WN3C@28221|Deltaproteobacteria,2Z350@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
CMS3_k127_2883498_6	706587.Desti_1364	9.123e-64	243.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MTH@68525|delta/epsilon subdivisions,2WJQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_2883498_5	882083.SacmaDRAFT_5689	1.191e-66	248.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DZD5@85010|Pseudonocardiales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_2883498_1	1068978.AMETH_0143	3.577e-177	584.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DZ2U@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-forming long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_2883498_4	1121272.KB903272_gene441	2.94e-91	306.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DDVG@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_2883498_8	765913.ThidrDRAFT_0007	7.194e-33	131.0	2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,1SCKY@1236|Gammaproteobacteria,1WZI2@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS3_k127_2883498_3	443218.AS9A_3955	1.867e-92	310.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,232CN@1762|Mycobacteriaceae	201174|Actinobacteria	E	amino acid	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS3_k127_2883498_9	1382306.JNIM01000001_gene2872	2.93e-28	123.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS3_k127_2897459_1	298653.Franean1_3452	4.338e-22	109.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
CMS3_k127_2897459_0	886293.Sinac_1156	1.208e-162	528.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2906269_3	325452.fgenesh_scip_prom.46568.139	7.655e-64	244.0	2C5PI@1|root,2RXBV@2759|Eukaryota,3Q9YB@4776|Peronosporales	4776|Peronosporales	S	Transglutaminase elicitor	-	-	-	-	-	-	-	-	-	-	-	-	TGase_elicitor
CMS3_k127_2906269_6	1278073.MYSTI_00814	1.351e-26	127.0	COG1520@1|root,COG2234@1|root,COG1520@2|Bacteria,COG2234@2|Bacteria,1NI1E@1224|Proteobacteria,430IZ@68525|delta/epsilon subdivisions,2WW3C@28221|Deltaproteobacteria,2YYH1@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M10
CMS3_k127_2906269_0	861299.J421_4060	0.0	1054.0	COG2352@1|root,COG2352@2|Bacteria,1ZSSH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS3_k127_2906269_4	378806.STAUR_2938	1.2e-35	138.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,42UHB@68525|delta/epsilon subdivisions,2WQHM@28221|Deltaproteobacteria,2YVPY@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS3_k127_2906269_2	1040989.AWZU01000020_gene2066	1.575e-64	238.0	COG2114@1|root,COG2114@2|Bacteria,1R51D@1224|Proteobacteria,2TT6W@28211|Alphaproteobacteria,3JVJI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_2906269_1	391625.PPSIR1_17405	1.047e-99	342.0	COG2843@1|root,COG2843@2|Bacteria,1N79C@1224|Proteobacteria,42UD7@68525|delta/epsilon subdivisions,2X609@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Capsule biosynthesis protein capA	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS3_k127_2906269_5	382464.ABSI01000013_gene1739	3.466e-27	122.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	ysnE	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_2907650_5	1192034.CAP_2998	3.291e-18	94.0	COG1309@1|root,COG1309@2|Bacteria,1MYFS@1224|Proteobacteria,42T8F@68525|delta/epsilon subdivisions,2WPCH@28221|Deltaproteobacteria,2Z34T@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2907650_3	502025.Hoch_0011	9.725e-60	209.0	COG1051@1|root,COG1051@2|Bacteria,1N5QT@1224|Proteobacteria,433SX@68525|delta/epsilon subdivisions,2WXYA@28221|Deltaproteobacteria,2YVMP@29|Myxococcales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_2907650_1	502025.Hoch_0012	1.115e-75	264.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2WRKW@28221|Deltaproteobacteria,2YVUK@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS3_k127_2907650_0	502025.Hoch_0013	6.717e-313	982.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2YU4B@29|Myxococcales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS3_k127_2907650_4	502025.Hoch_0014	4.167e-42	161.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions,2WMPN@28221|Deltaproteobacteria,2YVXC@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS3_k127_2907650_9	65071.PYU1_T004637	0.0005094	53.0	KOG1032@1|root,KOG1032@2759|Eukaryota,1MAX6@121069|Pythiales	121069|Pythiales	S	Protein kinase C conserved region 2 (CalB)	-	-	-	-	-	-	-	-	-	-	-	-	C2
CMS3_k127_2907650_7	68219.JNXI01000037_gene7838	9.184e-07	62.0	COG1409@1|root,COG1409@2|Bacteria,2GK31@201174|Actinobacteria	201174|Actinobacteria	M	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_2907650_6	1232410.KI421422_gene2002	6.995e-08	64.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WP7X@28221|Deltaproteobacteria,43SJJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
CMS3_k127_2907650_2	502025.Hoch_0017	3.612e-73	254.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2YVF4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS3_k127_2930743_3	502025.Hoch_5005	3.908e-109	357.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,437V8@68525|delta/epsilon subdivisions,2X34Q@28221|Deltaproteobacteria,2YU9A@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	dapE1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_2930743_6	861299.J421_1880	1.161e-36	144.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
CMS3_k127_2930743_4	502025.Hoch_5424	5.7e-67	237.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,43513@68525|delta/epsilon subdivisions,2X944@28221|Deltaproteobacteria,2Z1T3@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
CMS3_k127_2930743_0	502025.Hoch_2603	7.479e-266	834.0	COG0167@1|root,COG0479@1|root,COG0167@2|Bacteria,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.1.1,1.3.1.2,1.97.1.9	ko:K00207,ko:K12527,ko:K17723	ko00240,ko00410,ko00450,ko00770,ko00983,ko01100,map00240,map00410,map00450,map00770,map00983,map01100	M00046	R00977,R00978,R01414,R01415,R07229,R08226,R11026	RC00072,RC00123,RC02245,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	ATC_hydrolase,CCG,DHO_dh,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_20,Fer4_8,Pyr_redox_2
CMS3_k127_2930743_1	1121033.AUCF01000005_gene5211	4.298e-160	516.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2TR5X@28211|Alphaproteobacteria,2JPJY@204441|Rhodospirillales	204441|Rhodospirillales	E	Peptidase family M20/M25/M40	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_2930743_2	502025.Hoch_3413	5.163e-110	374.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WP4Z@28221|Deltaproteobacteria,2YU7V@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS3_k127_2930743_5	502025.Hoch_3414	7.814e-61	217.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
CMS3_k127_2931569_4	1297742.A176_02271	5.287e-100	349.0	COG0745@1|root,COG0784@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2Z2WF@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_2931569_2	574087.Acear_1523	1.626e-129	429.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3WAAZ@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_2931569_0	502025.Hoch_2332	1.804e-241	770.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria,2YUQR@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_2931569_3	502025.Hoch_2333	2.157e-102	373.0	COG3292@1|root,COG3292@2|Bacteria,1PCR9@1224|Proteobacteria,43E4V@68525|delta/epsilon subdivisions,2WZQV@28221|Deltaproteobacteria,2Z2J9@29|Myxococcales	28221|Deltaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2931569_6	502025.Hoch_0288	6.112e-56	207.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_2931569_5	502025.Hoch_2499	1.685e-92	312.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
CMS3_k127_2931569_7	215803.DB30_5907	7.02e-26	109.0	COG1225@1|root,COG1225@2|Bacteria,1PEII@1224|Proteobacteria,43434@68525|delta/epsilon subdivisions,2X503@28221|Deltaproteobacteria,2YZX7@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_2931569_9	1111729.ATYV01000002_gene2108	1.597e-11	66.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,22MX4@1653|Corynebacteriaceae	201174|Actinobacteria	O	bacterioferritin comigratory protein	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_2931569_8	1049564.TevJSym_bd00030	4.438e-12	71.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,1S1WE@1236|Gammaproteobacteria,1J73M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_2931569_1	502025.Hoch_2480	5.153e-150	490.0	COG0827@1|root,COG0827@2|Bacteria,1QX5V@1224|Proteobacteria,43BYE@68525|delta/epsilon subdivisions,2X9RH@28221|Deltaproteobacteria,2YX73@29|Myxococcales	28221|Deltaproteobacteria	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
CMS3_k127_2950337_0	215803.DB30_1928	1.04e-88	309.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria,2YU4W@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_2950337_1	502025.Hoch_5725	3.416e-67	244.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	imuB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS
CMS3_k127_2954249_1	502025.Hoch_6698	7.956e-55	195.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria,2YUE9@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_2954249_0	502025.Hoch_6697	0.0	1072.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria,2YU2Y@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
CMS3_k127_2957368_2	1254432.SCE1572_06465	1.063e-98	359.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_2957368_1	502025.Hoch_5988	1.194e-145	477.0	COG3850@1|root,COG3852@1|root,COG3850@2|Bacteria,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
CMS3_k127_2957368_0	502025.Hoch_5989	2.025e-200	656.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4M@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	sasR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2957368_5	1254432.SCE1572_44945	7.684e-14	73.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42MUA@68525|delta/epsilon subdivisions,2WJWH@28221|Deltaproteobacteria,2YWF4@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_2958038_2	502025.Hoch_2716	2.33e-142	464.0	COG0312@1|root,COG0312@2|Bacteria,1QM7I@1224|Proteobacteria,432IZ@68525|delta/epsilon subdivisions,2WYIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_2958038_0	502025.Hoch_2715	8.19e-236	750.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,43B01@68525|delta/epsilon subdivisions,2X6E4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_2958038_7	1192034.CAP_0208	1.415e-39	163.0	2BCR5@1|root,326BM@2|Bacteria,1QAS5@1224|Proteobacteria,43E3F@68525|delta/epsilon subdivisions,2WZKS@28221|Deltaproteobacteria,2Z2BX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2958038_4	102129.Lepto7375DRAFT_7637	1.636e-86	293.0	COG1738@1|root,COG1738@2|Bacteria,1G49U@1117|Cyanobacteria,1HEMD@1150|Oscillatoriales	1117|Cyanobacteria	U	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS3_k127_2958038_8	690850.Desaf_2163	3.919e-27	116.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS3_k127_2958038_5	690850.Desaf_2164	4.693e-81	283.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42N5I@68525|delta/epsilon subdivisions,2WM5T@28221|Deltaproteobacteria,2M9FV@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_31,Radical_SAM
CMS3_k127_2958038_6	304371.MCP_0732	4.543e-43	168.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_2958038_1	518766.Rmar_2644	3.82e-145	469.0	COG4663@1|root,COG4663@2|Bacteria,4PEE6@976|Bacteroidetes,1FIYV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_2958038_11	1192034.CAP_5083	1.336e-06	60.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HATPase_c,HisKA,NHL,Response_reg,SGL,Y_Y_Y
CMS3_k127_2958038_3	479434.Sthe_1140	3.157e-119	393.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_2958038_9	1340493.JNIF01000004_gene611	7.895e-18	95.0	COG0392@1|root,COG0392@2|Bacteria,3Y4Q3@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_2960160_10	765420.OSCT_0218	9.564e-09	56.0	COG1100@1|root,COG1100@2|Bacteria,2G6A7@200795|Chloroflexi,37523@32061|Chloroflexia	32061|Chloroflexia	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
CMS3_k127_2960160_7	573370.DMR_40890	2.188e-24	119.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Cytochrom_C,HEAT_2,HEAT_PBS,MFS_1,Peptidase_M1,S1
CMS3_k127_2960160_12	203119.Cthe_0488	6.772e-06	52.0	COG5581@1|root,COG5581@2|Bacteria,1VERW@1239|Firmicutes,24NU7@186801|Clostridia,3WNN9@541000|Ruminococcaceae	186801|Clostridia	M	Flagellar protein YcgR	pilZ	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
CMS3_k127_2960160_11	269799.Gmet_0829	5.13e-06	57.0	COG2201@1|root,COG2201@2|Bacteria,1QXP9@1224|Proteobacteria,43C53@68525|delta/epsilon subdivisions,2X7FF@28221|Deltaproteobacteria,43W48@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_2960160_5	443143.GM18_4429	2.759e-54	217.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
CMS3_k127_2960160_13	215803.DB30_0237	0.0003264	50.0	COG1413@1|root,COG1413@2|Bacteria,1PC98@1224|Proteobacteria,433V3@68525|delta/epsilon subdivisions,2X3KJ@28221|Deltaproteobacteria,2YWFM@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_2960160_1	1123368.AUIS01000004_gene281	1.183e-89	320.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Iron Permease	efeU_1	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrome_CBB3,FTR1
CMS3_k127_2960160_9	1244869.H261_19084	2.207e-16	85.0	2AM3J@1|root,33G8Q@2|Bacteria,1P03H@1224|Proteobacteria,2UUR0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2960160_8	1504981.KO116_1951	4.269e-18	100.0	28IX1@1|root,2Z8V3@2|Bacteria,1N0WD@1224|Proteobacteria,1RSH6@1236|Gammaproteobacteria,1XP8A@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
CMS3_k127_2960160_0	1242864.D187_007438	1.791e-139	450.0	2E55N@1|root,32ZYI@2|Bacteria,1NFET@1224|Proteobacteria,437UG@68525|delta/epsilon subdivisions,2X342@28221|Deltaproteobacteria,2YU52@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2960160_3	1242864.D187_007437	5.866e-61	216.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,42WRW@68525|delta/epsilon subdivisions,2WRCW@28221|Deltaproteobacteria,2YV18@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2960160_4	439235.Dalk_2288	2.591e-57	232.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2MPW6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
CMS3_k127_2960160_6	717785.HYPMC_1403	1.826e-26	120.0	28HBI@1|root,2Z7NH@2|Bacteria,1QZQ9@1224|Proteobacteria,2TYRS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF4241
CMS3_k127_2963404_1	1278073.MYSTI_01388	4.018e-21	108.0	COG3419@1|root,COG3419@2|Bacteria	2|Bacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
CMS3_k127_2963404_2	215803.DB30_5488	1.217e-15	87.0	2AYRE@1|root,31QWF@2|Bacteria,1QNFJ@1224|Proteobacteria,43DZP@68525|delta/epsilon subdivisions,2X93E@28221|Deltaproteobacteria,2Z1PQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2963404_0	502025.Hoch_3885	2.588e-136	458.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,42RUS@68525|delta/epsilon subdivisions,2WNWT@28221|Deltaproteobacteria,2YWJK@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CMS3_k127_2966254_5	349521.HCH_06592	2.391e-28	122.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_2966254_0	1280949.HAD_11995	1.703e-76	267.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRIH@28211|Alphaproteobacteria,43WPX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
CMS3_k127_2966254_7	1123234.AUKI01000013_gene1581	6.467e-18	98.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_2966254_6	1242864.D187_009328	3.183e-22	105.0	COG0784@1|root,COG1716@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG1716@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
CMS3_k127_2966254_2	448385.sce8943	1.559e-51	196.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,42UHJ@68525|delta/epsilon subdivisions,2WT4S@28221|Deltaproteobacteria,2YUXZ@29|Myxococcales	28221|Deltaproteobacteria	K	Arabinose-binding domain of AraC transcription regulator, N-term	oruR2	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
CMS3_k127_2966254_4	1523503.JPMY01000006_gene2096	1.479e-34	145.0	COG2207@1|root,COG2207@2|Bacteria,1RB13@1224|Proteobacteria,1S2ZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
CMS3_k127_2966254_1	1192034.CAP_2241	5.088e-72	262.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C,SdrD_B
CMS3_k127_2966254_3	478741.JAFS01000001_gene2071	5.051e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,46T9V@74201|Verrucomicrobia	74201|Verrucomicrobia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_2966254_8	448385.sce3350	1.289e-06	52.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42NXM@68525|delta/epsilon subdivisions,2X2A5@28221|Deltaproteobacteria,2YYZ5@29|Myxococcales	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_2968946_9	204669.Acid345_4155	4.912e-14	81.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria,2JIZ4@204432|Acidobacteriia	204432|Acidobacteriia	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
CMS3_k127_2968946_4	1499683.CCFF01000017_gene2750	6.829e-38	160.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24E02@186801|Clostridia,36WF1@31979|Clostridiaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_4,Big_5,CW_binding_2,GHL10
CMS3_k127_2968946_7	485918.Cpin_1365	2.153e-14	86.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_2968946_2	502025.Hoch_4845	7.342e-79	280.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2Z08W@29|Myxococcales	28221|Deltaproteobacteria	M	MltA specific insert domain	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
CMS3_k127_2968946_5	1299327.I546_6753	1.074e-31	138.0	COG3315@1|root,COG3315@2|Bacteria,2GN89@201174|Actinobacteria,2354J@1762|Mycobacteriaceae	201174|Actinobacteria	H	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_2968946_8	1068978.AMETH_2256	2.864e-14	86.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_2968946_1	502025.Hoch_6056	1.145e-82	287.0	COG0515@1|root,COG0515@2|Bacteria,1Q31E@1224|Proteobacteria,438RJ@68525|delta/epsilon subdivisions,2X991@28221|Deltaproteobacteria,2YXKM@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2968946_3	502025.Hoch_1803	6.883e-42	165.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2Z1R9@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS3_k127_2968946_6	502025.Hoch_0369	6.593e-27	127.0	COG2340@1|root,COG2340@2|Bacteria,1REVB@1224|Proteobacteria,4386P@68525|delta/epsilon subdivisions,2X3GI@28221|Deltaproteobacteria,2YW01@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_2968946_10	502025.Hoch_5444	7.555e-11	72.0	COG1366@1|root,COG1366@2|Bacteria,1NG3I@1224|Proteobacteria,42W69@68525|delta/epsilon subdivisions,2WS39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2980396_1	502025.Hoch_3706	2.004e-109	362.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42RDN@68525|delta/epsilon subdivisions,2WMR0@28221|Deltaproteobacteria,2YUAJ@29|Myxococcales	28221|Deltaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_2980396_0	502025.Hoch_3705	4.991e-194	631.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_2980396_2	391625.PPSIR1_09291	5.911e-79	269.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,2YUQJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS3_k127_2982245_4	448385.sce9236	2.922e-101	349.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
CMS3_k127_2982245_9	1254432.SCE1572_18375	1.657e-64	231.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,42NRH@68525|delta/epsilon subdivisions,2WNIB@28221|Deltaproteobacteria,2YV7G@29|Myxococcales	28221|Deltaproteobacteria	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
CMS3_k127_2982245_7	404589.Anae109_2327	1.332e-88	327.0	COG3506@1|root,COG5276@1|root,COG3506@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
CMS3_k127_2982245_11	502025.Hoch_2305	1.856e-30	138.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42W3M@68525|delta/epsilon subdivisions,2WRMB@28221|Deltaproteobacteria,2YYJR@29|Myxococcales	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	Cupin_2,UPF0054
CMS3_k127_2982245_0	502025.Hoch_2304	3.957e-222	709.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2YU9U@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
CMS3_k127_2982245_1	502025.Hoch_2303	2.9e-141	454.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2YTWI@29|Myxococcales	28221|Deltaproteobacteria	T	PhoH-like protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS3_k127_2982245_6	502025.Hoch_2302	1.215e-96	325.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales	28221|Deltaproteobacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
CMS3_k127_2982245_13	246197.MXAN_4742	1.962e-12	70.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2YW1W@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS3_k127_2982245_3	502025.Hoch_2328	6.724e-104	353.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42SNR@68525|delta/epsilon subdivisions,2WP96@28221|Deltaproteobacteria,2Z1UE@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS3_k127_2982245_14	7897.ENSLACP00000000182	2.904e-10	73.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BAFT@33208|Metazoa,3CRZB@33213|Bilateria,488S5@7711|Chordata,49EBI@7742|Vertebrata	33208|Metazoa	T	glomerular capillary formation	NOTCH3	GO:0000003,GO:0000122,GO:0000139,GO:0000278,GO:0000578,GO:0000902,GO:0000904,GO:0001525,GO:0001568,GO:0001654,GO:0001655,GO:0001667,GO:0001700,GO:0001708,GO:0001709,GO:0001736,GO:0001738,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0001822,GO:0001894,GO:0001932,GO:0001933,GO:0001944,GO:0002009,GO:0002052,GO:0002064,GO:0002065,GO:0002066,GO:0002164,GO:0002165,GO:0002213,GO:0002376,GO:0002520,GO:0002682,GO:0002683,GO:0002684,GO:0003002,GO:0003006,GO:0003008,GO:0003674,GO:0003682,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005768,GO:0005770,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0005911,GO:0005912,GO:0006109,GO:0006110,GO:0006139,GO:0006140,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006725,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007154,GO:0007155,GO:0007157,GO:0007162,GO:0007163,GO:0007164,GO:0007165,GO:0007166,GO:0007219,GO:0007221,GO:0007267,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007293,GO:0007297,GO:0007298,GO:0007304,GO:0007306,GO:0007308,GO:0007309,GO:0007314,GO:0007346,GO:0007350,GO:0007351,GO:0007386,GO:0007389,GO:0007391,GO:0007398,GO:0007399,GO:0007400,GO:0007403,GO:0007405,GO:0007409,GO:0007411,GO:0007417,GO:0007419,GO:0007420,GO:0007422,GO:0007423,GO:0007424,GO:0007440,GO:0007442,GO:0007443,GO:0007444,GO:0007446,GO:0007447,GO:0007449,GO:0007450,GO:0007451,GO:0007455,GO:0007460,GO:0007464,GO:0007472,GO:0007473,GO:0007474,GO:0007476,GO:0007478,GO:0007480,GO:0007483,GO:0007484,GO:0007485,GO:0007498,GO:0007517,GO:0007519,GO:0007521,GO:0007548,GO:0007552,GO:0007560,GO:0007568,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008045,GO:0008052,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008284,GO:0008340,GO:0008347,GO:0008356,GO:0008358,GO:0008407,GO:0008587,GO:0008593,GO:0008595,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009608,GO:0009611,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009948,GO:0009950,GO:0009952,GO:0009953,GO:0009954,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0009994,GO:0009996,GO:0010001,GO:0010160,GO:0010259,GO:0010453,GO:0010454,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010623,GO:0010628,GO:0010629,GO:0010631,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010721,GO:0010927,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0014016,GO:0014017,GO:0014019,GO:0014706,GO:0015629,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0016330,GO:0016331,GO:0016333,GO:0016348,GO:0016360,GO:0016477,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019827,GO:0019899,GO:0019953,GO:0021700,GO:0021781,GO:0022008,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022416,GO:0022603,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030029,GO:0030030,GO:0030036,GO:0030054,GO:0030097,GO:0030139,GO:0030154,GO:0030155,GO:0030182,GO:0030539,GO:0030703,GO:0030707,GO:0030708,GO:0030713,GO:0030718,GO:0030720,GO:0030808,GO:0030811,GO:0030855,GO:0030900,GO:0031090,GO:0031099,GO:0031175,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031344,GO:0031399,GO:0031400,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031984,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032774,GO:0032835,GO:0032872,GO:0032873,GO:0032989,GO:0032990,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035003,GO:0035107,GO:0035112,GO:0035114,GO:0035120,GO:0035126,GO:0035153,GO:0035155,GO:0035157,GO:0035161,GO:0035162,GO:0035163,GO:0035165,GO:0035166,GO:0035167,GO:0035168,GO:0035170,GO:0035171,GO:0035172,GO:0035203,GO:0035204,GO:0035214,GO:0035215,GO:0035218,GO:0035220,GO:0035222,GO:0035239,GO:0035265,GO:0035282,GO:0035285,GO:0035295,GO:0036011,GO:0036099,GO:0036335,GO:0038023,GO:0040007,GO:0040008,GO:0040011,GO:0042051,GO:0042060,GO:0042063,GO:0042067,GO:0042127,GO:0042175,GO:0042221,GO:0042246,GO:0042325,GO:0042326,GO:0042330,GO:0042386,GO:0042387,GO:0042461,GO:0042462,GO:0042478,GO:0042480,GO:0042592,GO:0042659,GO:0042675,GO:0042676,GO:0042686,GO:0042688,GO:0042689,GO:0042691,GO:0042692,GO:0042693,GO:0042706,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043296,GO:0043408,GO:0043409,GO:0043467,GO:0043470,GO:0043523,GO:0043525,GO:0043696,GO:0043697,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0045165,GO:0045168,GO:0045314,GO:0045316,GO:0045463,GO:0045465,GO:0045466,GO:0045468,GO:0045595,GO:0045596,GO:0045597,GO:0045610,GO:0045611,GO:0045612,GO:0045613,GO:0045614,GO:0045664,GO:0045665,GO:0045746,GO:0045747,GO:0045787,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0046328,GO:0046329,GO:0046331,GO:0046483,GO:0046530,GO:0046532,GO:0046533,GO:0046552,GO:0046661,GO:0046666,GO:0046667,GO:0046843,GO:0048052,GO:0048056,GO:0048138,GO:0048139,GO:0048190,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048542,GO:0048546,GO:0048563,GO:0048565,GO:0048568,GO:0048569,GO:0048580,GO:0048581,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048592,GO:0048598,GO:0048599,GO:0048608,GO:0048609,GO:0048619,GO:0048645,GO:0048646,GO:0048660,GO:0048661,GO:0048663,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048803,GO:0048805,GO:0048806,GO:0048808,GO:0048812,GO:0048844,GO:0048856,GO:0048858,GO:0048859,GO:0048863,GO:0048864,GO:0048865,GO:0048867,GO:0048869,GO:0048870,GO:0048871,GO:0048872,GO:0050673,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051093,GO:0051094,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051301,GO:0051489,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051890,GO:0051960,GO:0051961,GO:0051962,GO:0055123,GO:0060089,GO:0060249,GO:0060250,GO:0060255,GO:0060284,GO:0060288,GO:0060289,GO:0060322,GO:0060429,GO:0060491,GO:0060537,GO:0060538,GO:0060541,GO:0060562,GO:0060571,GO:0060581,GO:0060582,GO:0060840,GO:0061061,GO:0061326,GO:0061331,GO:0061333,GO:0061351,GO:0061382,GO:0061437,GO:0061438,GO:0061439,GO:0061440,GO:0061458,GO:0061525,GO:0061564,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070161,GO:0070302,GO:0070303,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072002,GO:0072006,GO:0072012,GO:0072089,GO:0072091,GO:0072102,GO:0072103,GO:0072104,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090130,GO:0090132,GO:0090304,GO:0090596,GO:0090598,GO:0097150,GO:0097435,GO:0097485,GO:0097659,GO:0097708,GO:0098588,GO:0098609,GO:0098727,GO:0098742,GO:0098791,GO:0098796,GO:0098797,GO:0098827,GO:0120032,GO:0120035,GO:0120036,GO:0120039,GO:1900087,GO:1900371,GO:1900542,GO:1901214,GO:1901216,GO:1901360,GO:1901362,GO:1901576,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902532,GO:1902679,GO:1902680,GO:1902692,GO:1902806,GO:1902808,GO:1903506,GO:1903507,GO:1903508,GO:1903578,GO:1903706,GO:1903707,GO:1905207,GO:2000026,GO:2000027,GO:2000043,GO:2000045,GO:2000047,GO:2000048,GO:2000112,GO:2000113,GO:2000177,GO:2000179,GO:2000648,GO:2000736,GO:2001013,GO:2001141,GO:2001169	-	ko:K02599,ko:K20994,ko:K20995	ko01522,ko04320,ko04330,ko04371,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04371,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002	-	-	-	Ank,Ank_2,Ank_5,DUF3454,EGF,EGF_CA,NOD,NODP,Notch,hEGF
CMS3_k127_2982245_12	1254432.SCE1572_07760	2.98e-27	125.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4
CMS3_k127_2982245_10	1278073.MYSTI_01311	2.717e-46	188.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS3_k127_2982245_2	1268072.PSAB_13060	1.668e-136	451.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HF1P@91061|Bacilli,26R7P@186822|Paenibacillaceae	91061|Bacilli	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_2982245_5	502025.Hoch_3690	7.441e-99	347.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,2YV7V@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS3_k127_2982245_8	502025.Hoch_3689	9.526e-78	268.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2YWS7@29|Myxococcales	28221|Deltaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CMS3_k127_3010050_3	469383.Cwoe_4749	2.727e-24	112.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS3_k127_3010050_0	1227739.Hsw_1984	3.392e-109	363.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,47JYE@768503|Cytophagia	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
CMS3_k127_3010050_2	404589.Anae109_4034	3.098e-37	145.0	COG2329@1|root,COG2329@2|Bacteria,1MZKW@1224|Proteobacteria,432JJ@68525|delta/epsilon subdivisions,2WZDH@28221|Deltaproteobacteria,2Z1WB@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_3010050_1	572479.Hprae_1576	1.235e-71	257.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WA5X@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS3_k127_3012476_3	502025.Hoch_4826	4.877e-136	440.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2YU38@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_3012476_1	502025.Hoch_4825	7.793e-160	521.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2WTQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2
CMS3_k127_3012476_23	1235279.C772_02852	5.585e-05	53.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,26CZA@186818|Planococcaceae	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS3_k127_3012476_14	1131269.AQVV01000113_gene241	8.732e-30	129.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS3_k127_3012476_0	502025.Hoch_2495	4.619e-241	759.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2YU58@29|Myxococcales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS3_k127_3012476_12	502025.Hoch_4493	1.38e-45	169.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,2YVW9@29|Myxococcales	28221|Deltaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_3012476_24	2074.JNYD01000010_gene1041	0.0001509	53.0	COG0631@1|root,COG0631@2|Bacteria,2IG4Z@201174|Actinobacteria,4E2PF@85010|Pseudonocardiales	201174|Actinobacteria	T	PFAM Protein phosphatase	prpB8	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_3012476_22	1278073.MYSTI_02737	1.633e-08	66.0	2BQRB@1|root,32JMY@2|Bacteria,1PDGZ@1224|Proteobacteria,435GN@68525|delta/epsilon subdivisions,2WZU3@28221|Deltaproteobacteria,2Z2RN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3012476_19	215803.DB30_3743	5.617e-17	84.0	2ANK2@1|root,31DJ5@2|Bacteria,1QAV5@1224|Proteobacteria,435BD@68525|delta/epsilon subdivisions,2WZNS@28221|Deltaproteobacteria,2Z2FM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3012476_5	319225.Plut_0237	9.926e-122	405.0	COG0621@1|root,COG0621@2|Bacteria,1FDCV@1090|Chlorobi	1090|Chlorobi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_3012476_8	1219065.VPR01S_23_00280	5.042e-94	329.0	COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria,1XWQ9@135623|Vibrionales	135623|Vibrionales	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M4,Peptidase_M4_C
CMS3_k127_3012476_17	103733.JNYO01000004_gene8067	1.755e-25	120.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria,4DXTV@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative serine esterase (DUF676)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF676,PGAP1
CMS3_k127_3012476_18	1254432.SCE1572_15265	2.43e-17	91.0	COG1965@1|root,COG1965@2|Bacteria,1QAVK@1224|Proteobacteria,435BR@68525|delta/epsilon subdivisions,2WZP7@28221|Deltaproteobacteria,2Z2G9@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the frataxin family	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
CMS3_k127_3012476_2	502025.Hoch_3630	3.406e-153	498.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
CMS3_k127_3012476_4	502025.Hoch_4033	2.742e-123	407.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YZ61@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS3_k127_3012476_7	502025.Hoch_4036	5.478e-106	364.0	COG0438@1|root,COG0438@2|Bacteria,1PXM8@1224|Proteobacteria,434P0@68525|delta/epsilon subdivisions,2X8YH@28221|Deltaproteobacteria,2Z11Z@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS3_k127_3012476_15	502025.Hoch_4037	1.732e-26	111.0	2BGQS@1|root,32APS@2|Bacteria,1QAWR@1224|Proteobacteria,43E4J@68525|delta/epsilon subdivisions,2X97X@28221|Deltaproteobacteria,2Z2HF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3012476_13	1125863.JAFN01000001_gene1391	9.371e-34	145.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
CMS3_k127_3012476_6	502025.Hoch_4038	1.161e-115	387.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2YV2N@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE,MFS_1
CMS3_k127_3012476_16	1198452.Jab_1c08030	3.238e-26	126.0	2DNKJ@1|root,32XZB@2|Bacteria,1NZ94@1224|Proteobacteria,2W3EW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3012476_9	1535287.JP74_11245	3.364e-65	235.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U1B8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_3013381_7	391625.PPSIR1_25711	8.025e-49	184.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_3013381_11	584708.Apau_0556	4.194e-36	153.0	COG1533@1|root,COG1533@2|Bacteria,3TBCX@508458|Synergistetes	508458|Synergistetes	L	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_3013381_3	1449353.JQMQ01000004_gene5962	1.063e-61	234.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,2NI6X@228398|Streptacidiphilus	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	ko:K21256	ko01059,ko01130,map01059,map01130	M00833,M00834	R11414	RC01363	ko00000,ko00001,ko00002	-	-	-	Trp_halogenase
CMS3_k127_3013381_8	1192034.CAP_1688	1.642e-47	193.0	COG0641@1|root,COG0641@2|Bacteria,1Q1I9@1224|Proteobacteria,435ES@68525|delta/epsilon subdivisions,2WZSC@28221|Deltaproteobacteria,2Z2N7@29|Myxococcales	28221|Deltaproteobacteria	C	radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3013381_5	502025.Hoch_4120	7.164e-53	196.0	COG1075@1|root,COG1075@2|Bacteria,1Q6AV@1224|Proteobacteria,432RP@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PGAP1-like protein	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	PGAP1
CMS3_k127_3013381_6	1254432.SCE1572_03090	1.662e-51	192.0	COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,42XWG@68525|delta/epsilon subdivisions,2WT8J@28221|Deltaproteobacteria,2YV7I@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS3_k127_3013381_0	1320556.AVBP01000013_gene1464	4.069e-92	321.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U35E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS3_k127_3013381_18	1254432.SCE1572_04970	1.546e-07	62.0	2AH1Z@1|root,317B3@2|Bacteria,1PYKX@1224|Proteobacteria,435FG@68525|delta/epsilon subdivisions,2WZT0@28221|Deltaproteobacteria,2Z2PH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3013381_10	502025.Hoch_5209	4.519e-37	140.0	2E6D6@1|root,3310T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3013381_9	502025.Hoch_0213	9.992e-38	160.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
CMS3_k127_3013381_20	435908.IDSA_01375	1.637e-05	55.0	COG4967@1|root,COG4967@2|Bacteria,1R7RM@1224|Proteobacteria,1S1SU@1236|Gammaproteobacteria,2QGRF@267893|Idiomarinaceae	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
CMS3_k127_3013381_12	502025.Hoch_0216	5.509e-28	123.0	COG4726@1|root,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX_N
CMS3_k127_3013381_17	391625.PPSIR1_41769	2.127e-13	81.0	COG2010@1|root,COG2010@2|Bacteria,1QX4J@1224|Proteobacteria,437VA@68525|delta/epsilon subdivisions,2X34V@28221|Deltaproteobacteria,2YUNT@29|Myxococcales	1224|Proteobacteria	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C,Cu2_monooxygen,Redoxin
CMS3_k127_3013381_15	502025.Hoch_5236	1.671e-15	80.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,43A6F@68525|delta/epsilon subdivisions,2XA3X@28221|Deltaproteobacteria,2Z18A@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
CMS3_k127_3013381_4	502025.Hoch_4714	1.409e-60	213.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,43A6F@68525|delta/epsilon subdivisions,2XA3X@28221|Deltaproteobacteria,2Z18A@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
CMS3_k127_3013381_1	927658.AJUM01000019_gene2652	2.155e-81	294.0	COG1502@1|root,COG3209@1|root,COG3210@1|root,COG1502@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,4NRMR@976|Bacteroidetes	976|Bacteroidetes	I	PLD-like domain	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS3_k127_3013381_16	1232410.KI421413_gene750	9.922e-15	86.0	COG2885@1|root,COG3210@1|root,COG5184@1|root,COG5276@1|root,COG2885@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_3013381_2	502025.Hoch_0217	1.929e-69	239.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YWJD@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3036348_3	1449076.JOOE01000001_gene2686	6.471e-67	248.0	COG0613@1|root,COG0613@2|Bacteria,1MXJ5@1224|Proteobacteria,2U1RY@28211|Alphaproteobacteria,2K0T0@204457|Sphingomonadales	204457|Sphingomonadales	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3036348_5	886293.Sinac_5490	1.453e-27	130.0	COG3118@1|root,COG3118@2|Bacteria,2J53R@203682|Planctomycetes	203682|Planctomycetes	O	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_3036348_4	483219.LILAB_15385	1.031e-45	181.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_3036348_7	452652.KSE_06560	0.0002091	52.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,2M15V@2063|Kitasatospora	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_3036348_2	378806.STAUR_7238	3.353e-110	378.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3036348_6	7739.XP_002604716.1	1.734e-16	87.0	KOG4297@1|root,KOG4729@1|root,KOG4297@2759|Eukaryota,KOG4729@2759|Eukaryota,38GR9@33154|Opisthokonta,3BBE1@33208|Metazoa,3CTZ0@33213|Bilateria,4803E@7711|Chordata	33208|Metazoa	TV	mannose binding	-	-	-	ko:K06560	ko04145,ko05152,map04145,map05152	-	-	-	ko00000,ko00001,ko04090,ko04091,ko04131	-	-	-	F5_F8_type_C,Gal_Lectin,LCCL,Laminin_G_3,Lectin_C,SEA
CMS3_k127_3036348_0	1192034.CAP_2901	8.542e-181	578.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YU40@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_3036348_1	1192034.CAP_2899	9.883e-158	506.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2WM39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3041451_4	502025.Hoch_3482	7.677e-61	228.0	2BPA6@1|root,32I21@2|Bacteria,1Q1NP@1224|Proteobacteria,437D0@68525|delta/epsilon subdivisions,2X2J2@28221|Deltaproteobacteria,2YVZ4@29|Myxococcales	28221|Deltaproteobacteria	S	Cytosol aminopeptidase family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M17_N
CMS3_k127_3041451_8	215803.DB30_0063	4.367e-35	138.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2YVKR@29|Myxococcales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS3_k127_3041451_5	1125863.JAFN01000001_gene28	2.604e-56	200.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS3_k127_3041451_0	502025.Hoch_3479	3.015e-155	501.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2YUHV@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS3_k127_3041451_3	502025.Hoch_3478	5.099e-69	239.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2YVMJ@29|Myxococcales	28221|Deltaproteobacteria	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS3_k127_3041451_1	502025.Hoch_3274	2.884e-141	458.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,2YUVJ@29|Myxococcales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
CMS3_k127_3041451_6	502025.Hoch_5647	5.36e-54	199.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2YVAV@29|Myxococcales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS3_k127_3041451_7	502025.Hoch_5648	1.508e-52	199.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2WP1V@28221|Deltaproteobacteria,2Z0C3@29|Myxococcales	28221|Deltaproteobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
CMS3_k127_3041451_2	502025.Hoch_5649	2.104e-112	366.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2YXTZ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_3052782_0	502025.Hoch_3713	1.291e-153	523.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Big_3_2,CARDB,F5_F8_type_C,FlgD_ig,PD40,Prenyltrans
CMS3_k127_3054722_1	1254432.SCE1572_20500	1.374e-142	467.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42UHA@68525|delta/epsilon subdivisions,2WQA0@28221|Deltaproteobacteria,2YUHZ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS3_k127_3054722_0	502025.Hoch_0068	2.245e-237	768.0	COG3227@1|root,COG3227@2|Bacteria,1Q6DC@1224|Proteobacteria,432XR@68525|delta/epsilon subdivisions,2WYJ7@28221|Deltaproteobacteria,2Z34H@29|Myxococcales	28221|Deltaproteobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3054722_6	1242864.D187_010446	5.985e-12	75.0	COG5036@1|root,COG5036@2|Bacteria	2|Bacteria	P	cellular response to phosphate starvation	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS3_k127_3054722_4	1379270.AUXF01000001_gene2335	1.476e-43	180.0	COG0627@1|root,COG0627@2|Bacteria,1ZU1Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_3054722_5	335543.Sfum_0992	9.653e-13	72.0	COG1734@1|root,COG1734@2|Bacteria,1Q0U6@1224|Proteobacteria,42W75@68525|delta/epsilon subdivisions,2WR7B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM zinc finger, DksA TraR C4-type	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS3_k127_3054722_2	502025.Hoch_0069	1.86e-142	455.0	COG0639@1|root,COG4103@1|root,COG0639@2|Bacteria,COG4103@2|Bacteria,1NJ9V@1224|Proteobacteria,438VE@68525|delta/epsilon subdivisions,2X417@28221|Deltaproteobacteria,2YXWH@29|Myxococcales	28221|Deltaproteobacteria	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_3070574_0	502025.Hoch_4784	2.945e-153	488.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,2YYG9@29|Myxococcales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
CMS3_k127_3070574_1	502025.Hoch_6837	4.168e-104	349.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS3_k127_3075416_8	575540.Isop_1328	8.886e-25	111.0	COG2856@1|root,COG2856@2|Bacteria,2J2FQ@203682|Planctomycetes	203682|Planctomycetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3075416_1	290397.Adeh_2895	4.238e-176	567.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_3075416_7	502025.Hoch_4673	4.888e-25	110.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2YW4G@29|Myxococcales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS3_k127_3075416_3	502025.Hoch_4674	2.916e-61	242.0	COG1266@1|root,COG1266@2|Bacteria,1QAGW@1224|Proteobacteria,43E11@68525|delta/epsilon subdivisions,2WZDX@28221|Deltaproteobacteria,2Z1XB@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_3075416_0	378806.STAUR_1719	1.247e-224	725.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2YTYJ@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_3075416_9	1242864.D187_008380	7.999e-12	76.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
CMS3_k127_3075416_11	110319.CF8_2756	3.942e-06	59.0	2E0VD@1|root,32WCN@2|Bacteria,2ITDY@201174|Actinobacteria	201174|Actinobacteria	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
CMS3_k127_3075416_6	1198452.Jab_2c25980	3.671e-37	157.0	COG2819@1|root,COG3408@1|root,COG2819@2|Bacteria,COG3408@2|Bacteria,1QWGV@1224|Proteobacteria,2W9X7@28216|Betaproteobacteria,476P3@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
CMS3_k127_3075416_10	378806.STAUR_3840	2.069e-11	76.0	COG0457@1|root,COG0457@2|Bacteria,1QX0H@1224|Proteobacteria,43C18@68525|delta/epsilon subdivisions,2X7BW@28221|Deltaproteobacteria,2YWZC@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_7
CMS3_k127_3075416_12	269799.Gmet_0559	1.309e-05	57.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
CMS3_k127_3075416_5	502025.Hoch_1339	2.775e-43	163.0	COG2197@1|root,COG2197@2|Bacteria,1RDUR@1224|Proteobacteria	1224|Proteobacteria	KT	COG2771 DNA-binding HTH domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS3_k127_3075416_4	709032.Sulku_0097	9.152e-45	167.0	COG2010@1|root,COG2010@2|Bacteria,1NKKK@1224|Proteobacteria,42UAC@68525|delta/epsilon subdivisions,2YRSI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CMS3_k127_3075416_2	1380394.JADL01000002_gene1789	4.825e-150	482.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TQSC@28211|Alphaproteobacteria,2JREM@204441|Rhodospirillales	204441|Rhodospirillales	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_3106223_7	1242864.D187_004507	9.261e-09	61.0	2BRHH@1|root,32KGG@2|Bacteria,1Q2UB@1224|Proteobacteria,438GJ@68525|delta/epsilon subdivisions,2X21P@28221|Deltaproteobacteria,2YWXE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3106223_6	1000565.METUNv1_00106	4.18e-35	145.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2VSQ1@28216|Betaproteobacteria,2KWPM@206389|Rhodocyclales	206389|Rhodocyclales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_3106223_4	1121104.AQXH01000001_gene1402	1.972e-76	275.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Laminin_G_3,Pkinase
CMS3_k127_3106223_0	502025.Hoch_5892	1.278e-120	394.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42RUT@68525|delta/epsilon subdivisions,2X9ZW@28221|Deltaproteobacteria,2Z1HJ@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_3106223_2	391625.PPSIR1_38731	1.798e-106	368.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2YWE1@29|Myxococcales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
CMS3_k127_3106223_8	391625.PPSIR1_38736	4.329e-08	63.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
CMS3_k127_3106223_5	391625.PPSIR1_38741	4.748e-64	232.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria,2Z1WI@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_3106223_1	502025.Hoch_5893	3.117e-108	363.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	1224|Proteobacteria	T	SMART protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_3106223_3	502025.Hoch_5894	3.257e-81	282.0	COG5459@1|root,COG5459@2|Bacteria,1MWMM@1224|Proteobacteria,42WIB@68525|delta/epsilon subdivisions,2WRHR@28221|Deltaproteobacteria,2Z341@29|Myxococcales	28221|Deltaproteobacteria	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
CMS3_k127_3106223_9	243924.LT42_15130	2.473e-07	61.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,1S6US@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3115186_1	1479239.JQMU01000001_gene1077	8.939e-25	105.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3115186_2	1479239.JQMU01000001_gene1077	2.994e-09	59.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3115186_0	324602.Caur_0649	2.811e-41	171.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_3115186_3	1137269.AZWL01000011_gene3221	3.007e-08	68.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_3137204_2	886293.Sinac_1156	2.104e-213	692.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_3137204_0	502025.Hoch_3784	0.0	1170.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2YUJ4@29|Myxococcales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
CMS3_k127_3137204_5	448385.sce8039	2.458e-92	312.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2YTTQ@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS3_k127_3137204_12	2045.KR76_23065	2.064e-24	111.0	COG2050@1|root,COG2050@2|Bacteria,2GK27@201174|Actinobacteria,4DRFE@85009|Propionibacteriales	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_3137204_1	502025.Hoch_3787	8.513e-214	694.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2YUG3@29|Myxococcales	28221|Deltaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_3137204_7	502025.Hoch_3785	8.208e-55	201.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,42SRU@68525|delta/epsilon subdivisions,2WPAI@28221|Deltaproteobacteria,2YVFH@29|Myxococcales	28221|Deltaproteobacteria	F	Peptidase C26	guaA2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS3_k127_3137204_15	1502850.FG91_00468	1.193e-08	68.0	COG1309@1|root,COG1309@2|Bacteria,1NCC9@1224|Proteobacteria,2UFYX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3137204_14	1280953.HOC_17831	1.793e-13	81.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria,43XPN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	COG0208 Ribonucleotide reductase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_3137204_4	1278073.MYSTI_02968	3.157e-131	453.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,42YBA@68525|delta/epsilon subdivisions,2WUP5@28221|Deltaproteobacteria,2YX31@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CMS3_k127_3137204_10	502025.Hoch_3506	3.856e-35	153.0	COG0406@1|root,COG0406@2|Bacteria,1QNKV@1224|Proteobacteria,435FE@68525|delta/epsilon subdivisions,2WZSY@28221|Deltaproteobacteria,2Z2PF@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_3137204_6	502025.Hoch_5388	1.791e-75	260.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,43824@68525|delta/epsilon subdivisions,2X3C7@28221|Deltaproteobacteria,2YVD2@29|Myxococcales	28221|Deltaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
CMS3_k127_3137204_3	502025.Hoch_3511	7.843e-146	492.0	COG4932@1|root,COG4932@2|Bacteria,1PF83@1224|Proteobacteria,430QE@68525|delta/epsilon subdivisions,2WVYF@28221|Deltaproteobacteria,2Z1TZ@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_3137204_8	502025.Hoch_3331	2.324e-52	195.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_3138295_8	706587.Desti_2505	5.391e-05	57.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
CMS3_k127_3138295_1	502025.Hoch_6498	3.433e-67	247.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,2YYW2@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS3_k127_3138295_9	1210884.HG799466_gene12790	0.0001315	52.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
CMS3_k127_3138295_0	502025.Hoch_0884	5.084e-101	349.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
CMS3_k127_3138295_3	111781.Lepto7376_1066	8.908e-19	92.0	COG2146@1|root,COG2146@2|Bacteria,1G6DV@1117|Cyanobacteria,1HB3V@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM Nitrite reductase NAD(P)H large subunit, NirD	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
CMS3_k127_3138295_7	313628.LNTAR_14097	8.409e-06	48.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	narB	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_3138295_2	391625.PPSIR1_18842	1.381e-33	134.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K13770,ko:K19736	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_3153139_6	1163617.SCD_n01356	4.796e-36	147.0	COG1638@1|root,COG1638@2|Bacteria,1PN6J@1224|Proteobacteria,2VSNQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_3153139_9	744979.R2A130_2000	2.474e-08	62.0	COG3090@1|root,COG3090@2|Bacteria,1RBHY@1224|Proteobacteria,2U681@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG3090 TRAP-type C4-dicarboxylate transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS3_k127_3153139_2	1177154.Y5S_01262	1.75e-106	366.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria,1XIS2@135619|Oceanospirillales	135619|Oceanospirillales	G	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS3_k127_3153139_1	502025.Hoch_4052	1.656e-107	355.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,42PEU@68525|delta/epsilon subdivisions,2WNNT@28221|Deltaproteobacteria,2Z2ZE@29|Myxococcales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS3_k127_3153139_4	448385.sce4952	1.016e-72	261.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria,2YUVI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_3153139_5	880073.Calab_1130	3.391e-56	213.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
CMS3_k127_3153139_0	502025.Hoch_3410	2.078e-147	474.0	COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,42TUC@68525|delta/epsilon subdivisions,2WQGC@28221|Deltaproteobacteria,2YUIJ@29|Myxococcales	28221|Deltaproteobacteria	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
CMS3_k127_3153139_7	1120944.JONS01000010_gene412	4.866e-30	133.0	COG1577@1|root,COG1577@2|Bacteria,2IAQ7@201174|Actinobacteria,4D443@85005|Actinomycetales	201174|Actinobacteria	I	GHMP kinases N terminal domain	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_3153139_3	502025.Hoch_3408	2.109e-99	346.0	COG3407@1|root,COG3407@2|Bacteria,1N5EZ@1224|Proteobacteria,4322G@68525|delta/epsilon subdivisions,2WWNM@28221|Deltaproteobacteria,2YUWJ@29|Myxococcales	28221|Deltaproteobacteria	I	GHMP kinases N terminal domain	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
CMS3_k127_3153139_8	1123284.KB899042_gene1427	1.668e-12	78.0	COG1304@1|root,COG1577@1|root,COG1304@2|Bacteria,COG1577@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,26PAG@186821|Sporolactobacillaceae	91061|Bacilli	C	FMN-dependent dehydrogenase	fni	GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
CMS3_k127_3172843_1	502025.Hoch_5472	1.117e-122	398.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YYM7@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS3_k127_3172843_0	502025.Hoch_5473	2.213e-196	624.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2YUNU@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS3_k127_3193148_0	880073.Calab_2583	4.61e-132	433.0	COG2230@1|root,COG2230@2|Bacteria,2NQ94@2323|unclassified Bacteria	2|Bacteria	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS3_k127_3193148_1	502025.Hoch_5632	1.857e-99	336.0	COG3239@1|root,COG3239@2|Bacteria,1PP7Y@1224|Proteobacteria,42YWN@68525|delta/epsilon subdivisions,2WUKG@28221|Deltaproteobacteria,2YYFI@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_3198313_2	448385.sce7960	4.822e-59	233.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,SapC
CMS3_k127_3198313_6	243090.RB4375	3.359e-20	106.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF642
CMS3_k127_3198313_5	1122176.KB903609_gene5148	5.649e-22	112.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_3198313_3	1254432.SCE1572_49150	1.14e-48	197.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria	1224|Proteobacteria	M	Spore Coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Cu-binding_MopE,Lectin_C
CMS3_k127_3198313_1	1144275.COCOR_05458	4.596e-65	235.0	COG0515@1|root,COG0515@2|Bacteria	1144275.COCOR_05458|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3198313_0	502025.Hoch_3365	2.221e-191	620.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YUET@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3198313_4	391625.PPSIR1_28826	1.289e-27	123.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3209112_1	502025.Hoch_2509	2.16e-106	356.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3209112_2	1267535.KB906767_gene3028	1.429e-38	160.0	COG2843@1|root,COG2843@2|Bacteria,3Y8HU@57723|Acidobacteria	57723|Acidobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
CMS3_k127_3209112_0	502025.Hoch_2516	0.0	1036.0	COG0793@1|root,COG1361@1|root,COG0793@2|Bacteria,COG1361@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WTUX@28221|Deltaproteobacteria,2YTTM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_3209112_5	398578.Daci_4515	1.588e-21	110.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
CMS3_k127_3209112_3	404589.Anae109_2915	2.08e-36	154.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3209112_4	1411123.JQNH01000001_gene2225	4.977e-33	144.0	COG2010@1|root,COG2010@2|Bacteria,1N0EF@1224|Proteobacteria,2U91T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_3209112_7	378806.STAUR_7393	1.509e-05	56.0	COG3391@1|root,COG3391@2|Bacteria,1QX9W@1224|Proteobacteria,43C32@68525|delta/epsilon subdivisions,2X7DQ@28221|Deltaproteobacteria,2YVS2@29|Myxococcales	28221|Deltaproteobacteria	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
CMS3_k127_322081_6	502025.Hoch_6432	1.741e-15	78.0	COG0312@1|root,COG0312@2|Bacteria,1Q3C0@1224|Proteobacteria,4393A@68525|delta/epsilon subdivisions,2X495@28221|Deltaproteobacteria,2YYIX@29|Myxococcales	28221|Deltaproteobacteria	S	peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_322081_2	502025.Hoch_0028	7.453e-69	237.0	COG1716@1|root,COG1716@2|Bacteria,1Q2NZ@1224|Proteobacteria,438A6@68525|delta/epsilon subdivisions,2X3JM@28221|Deltaproteobacteria,2YWCB@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_322081_1	502025.Hoch_0029	5.445e-86	306.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,42Q6E@68525|delta/epsilon subdivisions,2WJGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM cobalamin synthesis protein P47K	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
CMS3_k127_322081_5	7425.NV14267-PA	2.013e-27	129.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,41W55@6656|Arthropoda,3SG5T@50557|Insecta,46HA7@7399|Hymenoptera	33208|Metazoa	S	Domain of unknown function (DUF1736)	TMTC3	GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_322081_4	391600.ABRU01000051_gene638	2.644e-47	179.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria,2KGW8@204458|Caulobacterales	204458|Caulobacterales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS3_k127_322081_0	502025.Hoch_3167	2.998e-313	989.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
CMS3_k127_3222158_2	225937.HP15_830	4.102e-62	219.0	2B7YH@1|root,3215N@2|Bacteria,1RJP9@1224|Proteobacteria,1S6AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_3222158_1	502025.Hoch_4902	5.848e-132	446.0	COG1073@1|root,COG1073@2|Bacteria,1NKA5@1224|Proteobacteria,438I9@68525|delta/epsilon subdivisions,2X9SF@28221|Deltaproteobacteria,2YX1V@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3222158_0	448385.sce7451	2.516e-320	1022.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1PEH3@1224|Proteobacteria,430NV@68525|delta/epsilon subdivisions,2WW17@28221|Deltaproteobacteria,2YTSZ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_3222158_4	1297742.A176_00954	6.16e-22	108.0	COG1357@1|root,COG1357@2|Bacteria,1RJ94@1224|Proteobacteria,4374B@68525|delta/epsilon subdivisions,2X3P3@28221|Deltaproteobacteria,2YWQE@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3222158_5	502025.Hoch_6449	4.868e-17	92.0	2AIJ9@1|root,3191D@2|Bacteria,1Q1ER@1224|Proteobacteria,435I2@68525|delta/epsilon subdivisions,2WZVR@28221|Deltaproteobacteria,2Z2UM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3222158_6	1387312.BAUS01000004_gene1690	2.085e-12	79.0	2BUPG@1|root,32Q0G@2|Bacteria,1PJNT@1224|Proteobacteria,2W82M@28216|Betaproteobacteria,2KNHN@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3222158_3	1297742.A176_03545	3.776e-45	179.0	COG1376@1|root,COG1376@2|Bacteria,1NKBB@1224|Proteobacteria,432T9@68525|delta/epsilon subdivisions,2WYN9@28221|Deltaproteobacteria,2YWNH@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS3_k127_3302489_3	502025.Hoch_0478	3.318e-121	409.0	COG4145@1|root,COG4145@2|Bacteria,1PG56@1224|Proteobacteria,42YZC@68525|delta/epsilon subdivisions,2WTWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_3302489_24	502025.Hoch_6467	1.332e-05	55.0	2A4TP@1|root,30TF5@2|Bacteria,1PD8M@1224|Proteobacteria,435F0@68525|delta/epsilon subdivisions,2X98W@28221|Deltaproteobacteria,2Z2NT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302489_13	502025.Hoch_6468	2.895e-43	171.0	2A465@1|root,30SR9@2|Bacteria,1PC3P@1224|Proteobacteria,4388A@68525|delta/epsilon subdivisions,2X1C4@28221|Deltaproteobacteria,2YW6K@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302489_6	502025.Hoch_6469	8.631e-82	291.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_6469|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302489_7	1121481.AUAS01000006_gene877	2.615e-71	263.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
CMS3_k127_3302489_23	1134474.O59_000466	1.849e-06	57.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302489_12	502025.Hoch_5363	3.161e-49	184.0	COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions,2WQGU@28221|Deltaproteobacteria,2YVQK@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302489_19	598467.BrE312_0040	1.465e-18	89.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,1S3ER@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_3302489_21	1033810.HLPCO_002949	3.517e-12	69.0	COG2128@1|root,COG2128@2|Bacteria,2NS09@2323|unclassified Bacteria	2|Bacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_3302489_4	1192034.CAP_1695	8.696e-119	404.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_3302489_9	1173028.ANKO01000077_gene5321	3.196e-59	227.0	COG4359@1|root,COG4359@2|Bacteria,1G0UA@1117|Cyanobacteria,1H793@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like	-	-	3.1.3.87	ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07394	RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
CMS3_k127_3302489_8	211165.AJLN01000050_gene5227	2.33e-65	228.0	COG0235@1|root,COG0235@2|Bacteria,1G2EA@1117|Cyanobacteria,1JHFB@1189|Stigonemataceae	1117|Cyanobacteria	G	Class II Aldolase and Adducin N-terminal domain	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS3_k127_3302489_16	208444.JNYY01000016_gene923	1.715e-25	114.0	COG1881@1|root,COG2133@1|root,COG1881@2|Bacteria,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4E1H5@85010|Pseudonocardiales	201174|Actinobacteria	G	Carbohydrate binding module (family 35)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,CBM_6,GSDH,PBP,fn3
CMS3_k127_3302489_22	448385.sce5359	1.456e-10	74.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_3302489_17	670487.Ocepr_0253	1.146e-24	119.0	COG0546@1|root,COG0546@2|Bacteria,1WKUS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_3302489_5	502025.Hoch_5885	3.084e-102	354.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,439RM@68525|delta/epsilon subdivisions,2X54F@28221|Deltaproteobacteria,2Z03P@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_3302489_1	502025.Hoch_5887	8.869e-189	627.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_3302489_10	502025.Hoch_1893	1.334e-57	220.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2YUX4@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	coaE	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CoaE,PseudoU_synth_2,S4
CMS3_k127_3302489_2	502025.Hoch_1894	2.814e-139	469.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2WIQI@28221|Deltaproteobacteria,2YUSK@29|Myxococcales	28221|Deltaproteobacteria	H	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_3302489_15	502025.Hoch_2512	1.523e-36	149.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302489_0	502025.Hoch_1895	5.392e-218	696.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42MWF@68525|delta/epsilon subdivisions,2WKAQ@28221|Deltaproteobacteria,2Z2XM@29|Myxococcales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS3_k127_3302489_18	502025.Hoch_1896	5.004e-19	89.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_3302489_11	502025.Hoch_1897	3.672e-53	196.0	2EI76@1|root,33BYI@2|Bacteria,1NMIN@1224|Proteobacteria,42XUD@68525|delta/epsilon subdivisions,2WSV6@28221|Deltaproteobacteria,2Z2Z6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302489_20	502025.Hoch_1898	8.985e-18	83.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,42WB9@68525|delta/epsilon subdivisions,2WSSJ@28221|Deltaproteobacteria,2YVJB@29|Myxococcales	28221|Deltaproteobacteria	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
CMS3_k127_3302521_2	1278073.MYSTI_03555	1.577e-153	496.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X7H1@28221|Deltaproteobacteria,2Z3GB@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_3302521_0	886293.Sinac_1156	1.072e-309	991.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_3302521_11	926549.KI421517_gene2074	1.654e-07	63.0	2EHJH@1|root,336RS@2|Bacteria,4NX01@976|Bacteroidetes,47SDR@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302521_10	1407650.BAUB01000001_gene48	1.502e-23	106.0	2E60I@1|root,330PY@2|Bacteria,1G8Z3@1117|Cyanobacteria,1H2XK@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF4333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4333
CMS3_k127_3302521_5	1487953.JMKF01000078_gene4088	1.065e-102	343.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3302521_1	1254432.SCE1572_31930	1.089e-170	573.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,4389V@68525|delta/epsilon subdivisions,2X3J8@28221|Deltaproteobacteria,2YWAY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3302521_9	378806.STAUR_5345	8.364e-34	143.0	COG5083@1|root,COG5083@2|Bacteria,1R6Q7@1224|Proteobacteria,434SH@68525|delta/epsilon subdivisions,2X905@28221|Deltaproteobacteria,2Z191@29|Myxococcales	28221|Deltaproteobacteria	S	LNS2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3302521_4	502025.Hoch_6778	1.634e-104	347.0	COG0491@1|root,COG0491@2|Bacteria,1Q2NG@1224|Proteobacteria,4389J@68525|delta/epsilon subdivisions,2X3IZ@28221|Deltaproteobacteria,2YWA6@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_3302521_6	502025.Hoch_5720	5.964e-71	266.0	COG0318@1|root,COG0318@2|Bacteria,1MW0Y@1224|Proteobacteria,42SEI@68525|delta/epsilon subdivisions,2WPEN@28221|Deltaproteobacteria,2YY7E@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3302521_8	502025.Hoch_5719	5.724e-55	207.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,42WKH@68525|delta/epsilon subdivisions,2WSGE@28221|Deltaproteobacteria,2YVQV@29|Myxococcales	28221|Deltaproteobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS3_k127_3302521_3	1254432.SCE1572_18300	1.344e-109	365.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S34@68525|delta/epsilon subdivisions,2X5AY@28221|Deltaproteobacteria,2Z34Z@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_330342_3	1304872.JAGC01000003_gene2864	3.237e-106	351.0	COG3866@1|root,COG3866@2|Bacteria,1RFAV@1224|Proteobacteria	1224|Proteobacteria	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_330342_1	1192034.CAP_1232	2.285e-144	470.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2WNNB@28221|Deltaproteobacteria,2YUAE@29|Myxococcales	28221|Deltaproteobacteria	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_330342_6	502025.Hoch_4487	5.079e-54	197.0	COG3794@1|root,COG3794@2|Bacteria,1Q9I8@1224|Proteobacteria,42XQQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
CMS3_k127_330342_12	1125863.JAFN01000001_gene3000	1.034e-15	87.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_330342_9	502025.Hoch_0083	4.71e-33	139.0	2BIBC@1|root,32CH4@2|Bacteria,1PDD7@1224|Proteobacteria,435G3@68525|delta/epsilon subdivisions,2WZTJ@28221|Deltaproteobacteria,2Z2QE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_330342_10	448385.sce7743	2.39e-29	136.0	COG1595@1|root,COG1595@2|Bacteria,1QA32@1224|Proteobacteria,434TA@68525|delta/epsilon subdivisions,2WZ4A@28221|Deltaproteobacteria,2Z1AN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_330342_13	1278073.MYSTI_04558	9.136e-15	88.0	COG0810@1|root,COG1716@1|root,COG0810@2|Bacteria,COG1716@2|Bacteria,1QX84@1224|Proteobacteria,430UC@68525|delta/epsilon subdivisions,2WVSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
CMS3_k127_330342_5	1242864.D187_008335	1.409e-73	260.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,42TXY@68525|delta/epsilon subdivisions,2WK09@28221|Deltaproteobacteria,2YYEE@29|Myxococcales	28221|Deltaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
CMS3_k127_330342_2	1254432.SCE1572_40655	1.06e-120	397.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,42M3Z@68525|delta/epsilon subdivisions,2WJIR@28221|Deltaproteobacteria,2YWFB@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
CMS3_k127_330342_0	391625.PPSIR1_36202	1.647e-154	520.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria,2YV4I@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C7
CMS3_k127_330342_8	502025.Hoch_6493	1.188e-39	161.0	29RMJ@1|root,30CQT@2|Bacteria,1QTPA@1224|Proteobacteria,4380Z@68525|delta/epsilon subdivisions,2X3B0@28221|Deltaproteobacteria,2YV6U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_330342_4	502025.Hoch_1915	3.004e-81	287.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2YZYM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
CMS3_k127_330759_2	1125863.JAFN01000001_gene2582	5.87e-94	316.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_330759_0	502025.Hoch_0395	4.65e-156	516.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2YTVG@29|Myxococcales	28221|Deltaproteobacteria	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
CMS3_k127_330759_1	502025.Hoch_0394	1.041e-121	398.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2YUVY@29|Myxococcales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_3319684_21	502025.Hoch_5192	2.475e-36	154.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440,SnoaL_2,SnoaL_3
CMS3_k127_3319684_26	500153.JOEK01000012_gene1295	7.232e-19	100.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria	201174|Actinobacteria	NU	MobA-related protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_3319684_7	502025.Hoch_5194	1.099e-106	358.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria,2Z3DA@29|Myxococcales	28221|Deltaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS3_k127_3319684_14	502025.Hoch_6704	3.475e-64	234.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_6704|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_17	402777.KB235904_gene3158	2.851e-52	201.0	COG0642@1|root,COG2199@1|root,COG3437@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_3319684_15	443143.GM18_0075	1.944e-57	227.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,dCache_3
CMS3_k127_3319684_12	502025.Hoch_5196	2.01e-71	249.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,42P98@68525|delta/epsilon subdivisions,2WJWW@28221|Deltaproteobacteria,2YVRM@29|Myxococcales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS3_k127_3319684_1	502025.Hoch_6408	6.168e-215	685.0	COG1044@1|root,COG1044@2|Bacteria,1R0DU@1224|Proteobacteria,43CWB@68525|delta/epsilon subdivisions,2X84C@28221|Deltaproteobacteria,2YZ3S@29|Myxococcales	28221|Deltaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
CMS3_k127_3319684_0	502025.Hoch_6407	1.283e-220	705.0	COG3292@1|root,COG3292@2|Bacteria,1Q3P3@1224|Proteobacteria,439GA@68525|delta/epsilon subdivisions,2X4S8@28221|Deltaproteobacteria,2YZHD@29|Myxococcales	28221|Deltaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_18	1192034.CAP_8147	3.008e-46	191.0	COG0613@1|root,COG0613@2|Bacteria,1R4N5@1224|Proteobacteria	1224|Proteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_10	502025.Hoch_4058	5.307e-85	305.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YYKD@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_3319684_30	1227453.C444_10259	6.157e-10	72.0	COG1653@1|root,arCOG00151@2157|Archaea,2Y2AY@28890|Euryarchaeota,23Z4Y@183963|Halobacteria	183963|Halobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_32	1379698.RBG1_1C00001G0853	1.748e-07	61.0	290MS@1|root,2ZNA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_5	502025.Hoch_5044	7.298e-143	468.0	2ANJD@1|root,31DIF@2|Bacteria,1QAU4@1224|Proteobacteria,43E3V@68525|delta/epsilon subdivisions,2WZMZ@28221|Deltaproteobacteria,2Z0Q6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_4	56110.Oscil6304_1643	9.861e-153	511.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_3319684_22	502025.Hoch_5627	8.645e-28	131.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
CMS3_k127_3319684_27	1161401.ASJA01000019_gene1166	3.85e-16	92.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,43WVT@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG1520 FOG WD40-like repeat	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS3_k127_3319684_2	502025.Hoch_5527	3.654e-210	674.0	COG1409@1|root,COG1409@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2X67D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_3319684_28	502025.Hoch_5526	2.464e-14	77.0	29Z2K@1|root,30M04@2|Bacteria,1QAUM@1224|Proteobacteria,43E42@68525|delta/epsilon subdivisions,2WZNA@28221|Deltaproteobacteria,2Z2EY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_19	502025.Hoch_6405	1.11e-37	155.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_6405|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3319684_29	502025.Hoch_1579	2.296e-11	75.0	COG0515@1|root,COG0515@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_3319684_13	502025.Hoch_6404	6.209e-66	245.0	COG0328@1|root,COG0328@2|Bacteria,1PE5Y@1224|Proteobacteria,42RJY@68525|delta/epsilon subdivisions,2WNDP@28221|Deltaproteobacteria,2Z32P@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS3_k127_3319684_8	502025.Hoch_0518	1.591e-97	328.0	COG0726@1|root,COG0726@2|Bacteria,1MWYU@1224|Proteobacteria,4317N@68525|delta/epsilon subdivisions,2WWU5@28221|Deltaproteobacteria,2YV2P@29|Myxococcales	28221|Deltaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_3319684_9	502025.Hoch_0517	6.385e-97	322.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3319684_25	1345697.M493_03215	2.198e-20	104.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1WFAK@129337|Geobacillus	91061|Bacilli	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_3319684_6	502025.Hoch_0516	1.467e-112	373.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42PI0@68525|delta/epsilon subdivisions,2WJ79@28221|Deltaproteobacteria,2YUU7@29|Myxococcales	28221|Deltaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_3319684_3	502025.Hoch_0515	1.491e-155	522.0	COG1807@1|root,COG1807@2|Bacteria,1P6BI@1224|Proteobacteria,433Q7@68525|delta/epsilon subdivisions,2WXUY@28221|Deltaproteobacteria,2Z13P@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3319684_23	502025.Hoch_0514	5.108e-26	111.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_3319684_31	1223545.GS4_07_00360	2.052e-09	69.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4GBH3@85026|Gordoniaceae	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
CMS3_k127_3324279_0	483219.LILAB_35260	5.558e-120	390.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2YU0I@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
CMS3_k127_3324279_7	309807.SRU_2104	2.712e-26	117.0	COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1FJ8P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Protein of unknown function (DUF3341)	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS3_k127_3324279_5	1297742.A176_05067	4.449e-45	177.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_3324279_4	1297742.A176_05066	2.223e-59	227.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YY91@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3324279_1	697282.Mettu_0164	6.708e-75	256.0	COG0491@1|root,COG0491@2|Bacteria,1RGCD@1224|Proteobacteria,1S4WB@1236|Gammaproteobacteria,1XF0G@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
CMS3_k127_3324279_2	671143.DAMO_0610	7.179e-62	228.0	COG0494@1|root,COG0494@2|Bacteria,2NPTC@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_3324279_6	671143.DAMO_0483	3.359e-37	155.0	COG3222@1|root,COG3222@2|Bacteria,2NRHT@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS3_k127_3324279_9	502025.Hoch_4798	1.512e-06	61.0	28PPK@1|root,2ZCC0@2|Bacteria,1RBNQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3343534_1	243090.RB6432	7.086e-22	98.0	COG2010@1|root,COG2755@1|root,COG5297@1|root,COG2010@2|Bacteria,COG2755@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Alginate_lyase2,Lipase_GDSL_2
CMS3_k127_3343534_0	208439.AJAP_02075	1.77e-70	253.0	COG4399@1|root,COG4399@2|Bacteria,2GMW6@201174|Actinobacteria,4E0Z2@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
CMS3_k127_3343534_3	215803.DB30_0715	1.036e-14	86.0	2BRBM@1|root,32KA6@2|Bacteria,1Q2R1@1224|Proteobacteria,438CK@68525|delta/epsilon subdivisions,2X3MX@28221|Deltaproteobacteria,2YWJU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3343534_2	502025.Hoch_5485	3.02e-18	85.0	2AIXE@1|root,319F2@2|Bacteria,1Q2IN@1224|Proteobacteria,4385F@68525|delta/epsilon subdivisions,2X3FF@28221|Deltaproteobacteria,2YVUW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3365547_9	357808.RoseRS_2906	1.628e-26	121.0	COG2091@1|root,COG2091@2|Bacteria,2G74T@200795|Chloroflexi,377PA@32061|Chloroflexia	32061|Chloroflexia	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_3365547_0	383372.Rcas_2879	0.0	2563.0	COG0236@1|root,COG0304@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG0304@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2G68I@200795|Chloroflexi,3765Y@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_3365547_2	765420.OSCT_0508	6.472e-188	602.0	COG1960@1|root,COG1960@2|Bacteria,2G7Q9@200795|Chloroflexi,37704@32061|Chloroflexia	32061|Chloroflexia	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3365547_5	1380390.JIAT01000010_gene4575	9.753e-84	296.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_3365547_1	448385.sce0471	4.029e-278	865.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
CMS3_k127_3365547_11	391625.PPSIR1_05308	6.844e-24	119.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	AhpC-TSA,DUF5011,MRJP,NHL,SGL,Thioredoxin_8
CMS3_k127_3365547_10	1002809.SSIL_0823	7.719e-26	120.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,26EBR@186818|Planococcaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF1080,GDPD
CMS3_k127_3365547_14	1120951.AUBG01000003_gene2761	0.0002372	48.0	2E3AK@1|root,32YA3@2|Bacteria,4PQ2A@976|Bacteroidetes,1IKYT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3365547_13	882086.SacxiDRAFT_1874	4.761e-06	53.0	COG1737@1|root,COG1737@2|Bacteria,2GSSP@201174|Actinobacteria,4EB5N@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CMS3_k127_3365547_12	273057.SSO2309	1.372e-21	110.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Radical_SAM,SPASM
CMS3_k127_3365547_7	439235.Dalk_1479	1.432e-40	173.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
CMS3_k127_3365547_4	1047013.AQSP01000138_gene1035	9.183e-88	309.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_3365547_6	246197.MXAN_2738	1.41e-75	286.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,43AJ6@68525|delta/epsilon subdivisions,2X5ZG@28221|Deltaproteobacteria,2Z37W@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7,zf-HC2
CMS3_k127_3365547_3	448385.sce4185	1.263e-170	555.0	COG5184@1|root,COG5184@2|Bacteria,1PEJQ@1224|Proteobacteria,439SY@68525|delta/epsilon subdivisions,2X560@28221|Deltaproteobacteria,2Z05W@29|Myxococcales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_3365547_8	7739.XP_002611076.1	2.157e-28	132.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,48CY1@7711|Chordata	33208|Metazoa	T	EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_3,EGF_CA,Lectin_C,TIL
CMS3_k127_3369872_1	502025.Hoch_6870	9.857e-194	622.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2YUDA@29|Myxococcales	28221|Deltaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS3_k127_3369872_9	502025.Hoch_6869	1.107e-42	159.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,2YW2J@29|Myxococcales	28221|Deltaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS3_k127_3369872_6	215803.DB30_6035	9.155e-74	252.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2YYNH@29|Myxococcales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS3_k127_3369872_7	502025.Hoch_6867	3.562e-66	230.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2YV9Q@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
CMS3_k127_3369872_3	502025.Hoch_6866	2.414e-112	364.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
CMS3_k127_3369872_8	502025.Hoch_6865	2.777e-62	237.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993,ko:K02022,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_3369872_13	502025.Hoch_0375	5.392e-23	99.0	2ANKT@1|root,31DK0@2|Bacteria,1QAVU@1224|Proteobacteria,435BY@68525|delta/epsilon subdivisions,2X9SV@28221|Deltaproteobacteria,2Z2GU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3369872_15	545696.HOLDEFILI_00962	3.381e-08	65.0	COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,3VQBD@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_3369872_14	1048339.KB913029_gene2741	1.246e-17	96.0	COG5542@1|root,COG5542@2|Bacteria,2HJW5@201174|Actinobacteria,4ETD2@85013|Frankiales	201174|Actinobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
CMS3_k127_3369872_12	1049564.TevJSym_ac01880	3.933e-33	149.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	nucH	-	3.1.3.5	ko:K01081,ko:K07004	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Exo_endo_phos,LTD,Metallophos
CMS3_k127_3369872_10	246197.MXAN_5043	1.904e-42	179.0	COG1506@1|root,COG2911@1|root,COG1506@2|Bacteria,COG2911@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_3369872_0	502025.Hoch_0376	1.061e-222	712.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WQFJ@28221|Deltaproteobacteria,2YV3N@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L,TPR_16,TPR_6
CMS3_k127_3369872_2	485913.Krac_7836	1.805e-148	485.0	COG1960@1|root,COG1960@2|Bacteria,2G7JH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_3369872_11	349102.Rsph17025_0585	2.874e-40	159.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,1FCB1@1060|Rhodobacter	28211|Alphaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS3_k127_3369872_4	502025.Hoch_4903	7.09e-95	320.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2YUWB@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS3_k127_3369872_5	502025.Hoch_6356	4.022e-88	296.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YTVN@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Pkinase,PocR,Sigma54_activat
CMS3_k127_3407123_1	644282.Deba_1925	1.822e-71	271.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2WJ7P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Peptidase M18, aminopeptidase I	apeA	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
CMS3_k127_3407123_3	370438.PTH_2904	6.766e-35	155.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,260KK@186807|Peptococcaceae	186801|Clostridia	E	PFAM Peptidase M18, aminopeptidase I	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
CMS3_k127_3407123_0	1192034.CAP_8789	7.53e-92	323.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	DUF5001,PHP
CMS3_k127_3407123_2	313628.LNTAR_18915	8.455e-64	225.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	ycbL	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_3407123_4	143224.JQMD01000002_gene263	2.52e-31	134.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,1I7V8@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS3_k127_3431382_4	502025.Hoch_4468	2.15e-95	336.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K02487,ko:K03832,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02000,ko02022,ko02035	2.C.1.1	-	-	CarbopepD_reg_2,FabA,KAsynt_C_assoc,Ketoacyl-synt_C,TonB_2,TonB_C,ketoacyl-synt
CMS3_k127_3431382_14	1178825.ALIH01000004_gene2985	8.593e-07	61.0	COG1470@1|root,COG2911@1|root,COG3209@1|root,COG3291@1|root,COG5184@1|root,COG1470@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3
CMS3_k127_3431382_12	1283299.AUKG01000001_gene2742	1.551e-20	92.0	COG4770@1|root,COG4770@2|Bacteria,2HRMS@201174|Actinobacteria,4CTPT@84995|Rubrobacteria	84995|Rubrobacteria	I	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
CMS3_k127_3431382_9	502025.Hoch_3306	1.217e-42	178.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	ycf22	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_3431382_0	502025.Hoch_3307	2.906e-129	422.0	COG1463@1|root,COG1463@2|Bacteria,1QTED@1224|Proteobacteria,437WX@68525|delta/epsilon subdivisions,2WWP6@28221|Deltaproteobacteria,2YVFU@29|Myxococcales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_3431382_3	502025.Hoch_3439	7.346e-102	349.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2YY7F@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter, ATP-binding protein	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_3431382_7	502025.Hoch_3440	1.615e-71	264.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,439ZR@68525|delta/epsilon subdivisions,2X1ZB@28221|Deltaproteobacteria,2YVE8@29|Myxococcales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_3431382_8	1192034.CAP_7067	7.55e-66	233.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,430J8@68525|delta/epsilon subdivisions,2WVN6@28221|Deltaproteobacteria,2Z0T2@29|Myxococcales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_3431382_6	502025.Hoch_3442	2.171e-92	309.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2YZVX@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
CMS3_k127_3431382_10	448385.sce2043	1.991e-28	133.0	2BP52@1|root,32HVW@2|Bacteria,1QAR1@1224|Proteobacteria,4358W@68525|delta/epsilon subdivisions,2WZK1@28221|Deltaproteobacteria,2Z2AG@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
CMS3_k127_3431382_1	502025.Hoch_3444	1.183e-118	396.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_3431382_15	1121104.AQXH01000001_gene1459	2.439e-05	57.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NRVM@976|Bacteroidetes,1IQDC@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
CMS3_k127_3431382_11	502025.Hoch_3445	8.182e-24	116.0	2A7HH@1|root,30WF4@2|Bacteria,1QATQ@1224|Proteobacteria,435AN@68525|delta/epsilon subdivisions,2WZMS@28221|Deltaproteobacteria,2Z2E3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3431382_2	502025.Hoch_3446	2.605e-116	396.0	COG0392@1|root,COG0392@2|Bacteria,1N7DR@1224|Proteobacteria,42N4R@68525|delta/epsilon subdivisions,2WS5Z@28221|Deltaproteobacteria,2Z11V@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_3431382_5	502025.Hoch_3447	7.129e-93	310.0	COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,42UBJ@68525|delta/epsilon subdivisions,2WQ5M@28221|Deltaproteobacteria,2YVNX@29|Myxococcales	28221|Deltaproteobacteria	GM	PFAM PHP domain protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS3_k127_3465758_1	502025.Hoch_5225	9.618e-98	320.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,437U1@68525|delta/epsilon subdivisions,2X33K@28221|Deltaproteobacteria,2YU2K@29|Myxococcales	28221|Deltaproteobacteria	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_3465758_0	502025.Hoch_5224	1.078e-243	762.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_3468826_2	404589.Anae109_1753	1.062e-21	104.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_3468826_1	926569.ANT_03320	1.384e-65	247.0	COG0066@1|root,COG0066@2|Bacteria,2G6JE@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS3_k127_3468826_0	926569.ANT_03310	5.693e-213	669.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS3_k127_3507150_10	665571.STHERM_c17700	4.974e-57	208.0	COG0508@1|root,COG0508@2|Bacteria,2J5U3@203691|Spirochaetes	203691|Spirochaetes	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
CMS3_k127_3507150_6	502025.Hoch_4697	3.732e-81	294.0	COG0515@1|root,COG0515@2|Bacteria,1Q38J@1224|Proteobacteria,438ZJ@68525|delta/epsilon subdivisions,2X44T@28221|Deltaproteobacteria,2YY98@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	masK	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_3507150_12	502025.Hoch_6468	9.877e-34	150.0	2A465@1|root,30SR9@2|Bacteria,1PC3P@1224|Proteobacteria,4388A@68525|delta/epsilon subdivisions,2X1C4@28221|Deltaproteobacteria,2YW6K@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507150_4	502025.Hoch_5765	4.458e-93	332.0	COG2755@1|root,COG2755@2|Bacteria,1MXTS@1224|Proteobacteria	1224|Proteobacteria	E	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS3_k127_3507150_9	404589.Anae109_1571	1.983e-60	232.0	COG4932@1|root,COG4932@2|Bacteria,1PBE9@1224|Proteobacteria,433JD@68525|delta/epsilon subdivisions,2WXZR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507150_1	404589.Anae109_1570	4.381e-115	389.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
CMS3_k127_3507150_8	502025.Hoch_3527	1.616e-70	242.0	COG2952@1|root,COG2952@2|Bacteria,1QJIU@1224|Proteobacteria,43826@68525|delta/epsilon subdivisions,2X3CC@28221|Deltaproteobacteria,2YVDW@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF507)	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
CMS3_k127_3507150_11	502025.Hoch_3528	1.005e-40	154.0	COG1051@1|root,COG1051@2|Bacteria,1QZ5Q@1224|Proteobacteria,42TKI@68525|delta/epsilon subdivisions,2WQF6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_3507150_7	215803.DB30_3266	1.457e-71	259.0	COG0515@1|root,COG0515@2|Bacteria,1P2GW@1224|Proteobacteria,439GQ@68525|delta/epsilon subdivisions,2X4SQ@28221|Deltaproteobacteria,2YZIF@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3507150_2	502025.Hoch_2406	5.734e-112	396.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria,1MWRF@1224|Proteobacteria,42UA0@68525|delta/epsilon subdivisions,2WS4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
CMS3_k127_3507150_5	266117.Rxyl_0619	1.315e-90	312.0	COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CPZ9@84995|Rubrobacteria	84995|Rubrobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_3507150_3	502025.Hoch_3530	3.153e-111	378.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	-	-	-	ko:K12583	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_tran_28_C,Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3507150_0	285535.JOEY01000019_gene2400	1.763e-115	381.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3543032_3	502025.Hoch_1915	8.849e-19	89.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2YZYM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
CMS3_k127_3543032_0	502025.Hoch_4902	2.362e-114	394.0	COG1073@1|root,COG1073@2|Bacteria,1NKA5@1224|Proteobacteria,438I9@68525|delta/epsilon subdivisions,2X9SF@28221|Deltaproteobacteria,2YX1V@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3543032_4	357808.RoseRS_1736	5.891e-10	72.0	COG1413@1|root,COG1674@1|root,COG5635@1|root,COG1413@2|Bacteria,COG1674@2|Bacteria,COG5635@2|Bacteria,2G8R0@200795|Chloroflexi,3766B@32061|Chloroflexia	32061|Chloroflexia	CDT	Armadillo/beta-catenin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_3543032_2	378806.STAUR_5468	1.119e-39	160.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
CMS3_k127_3543032_1	929712.KI912613_gene1424	6.839e-44	185.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria,4CR2C@84995|Rubrobacteria	84995|Rubrobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_3544023_11	215803.DB30_4667	2.914e-12	74.0	2DJS1@1|root,30745@2|Bacteria,1Q2J3@1224|Proteobacteria,4385Y@68525|delta/epsilon subdivisions,2X3FS@28221|Deltaproteobacteria,2YVWX@29|Myxococcales	28221|Deltaproteobacteria	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
CMS3_k127_3544023_5	234267.Acid_1455	2.781e-79	293.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,3Y46R@57723|Acidobacteria	57723|Acidobacteria	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PDZ_2,Peptidase_M28
CMS3_k127_3544023_7	502025.Hoch_4134	1.507e-67	235.0	COG2050@1|root,COG2050@2|Bacteria,1RHAN@1224|Proteobacteria,43157@68525|delta/epsilon subdivisions,2WWIW@28221|Deltaproteobacteria,2YVGQ@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
CMS3_k127_3544023_3	234267.Acid_6655	2.519e-95	322.0	2C57D@1|root,2Z7RS@2|Bacteria,3Y3Y2@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
CMS3_k127_3544023_10	1121430.JMLG01000019_gene1658	2.652e-14	83.0	2AP46@1|root,31E5T@2|Bacteria,1V79Z@1239|Firmicutes,24J9W@186801|Clostridia,262MN@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3544023_12	378806.STAUR_1112	1.04e-10	69.0	COG0745@1|root,COG0745@2|Bacteria,1MZ7D@1224|Proteobacteria,42VVV@68525|delta/epsilon subdivisions,2WRBW@28221|Deltaproteobacteria,2YVNP@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_3544023_2	1254432.SCE1572_44935	1.957e-124	412.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P6D@68525|delta/epsilon subdivisions,2WM1P@28221|Deltaproteobacteria,2YUD4@29|Myxococcales	28221|Deltaproteobacteria	T	DNA-binding response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_3544023_13	1122605.KB893643_gene597	7.609e-10	63.0	2DJ8B@1|root,32UCJ@2|Bacteria,4NTR0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3544023_4	502025.Hoch_5785	1.666e-82	284.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
CMS3_k127_3544023_0	502025.Hoch_5784	1.45e-218	687.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
CMS3_k127_3544023_1	502025.Hoch_5783	1.439e-169	565.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glutamate-cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS3_k127_3544023_8	1121918.ARWE01000001_gene3018	2.977e-51	202.0	COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,42RKD@68525|delta/epsilon subdivisions,2WNAE@28221|Deltaproteobacteria,43USK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS3_k127_3544023_6	1123257.AUFV01000009_gene2205	3.241e-76	264.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,1RQII@1236|Gammaproteobacteria,1X9KK@135614|Xanthomonadales	135614|Xanthomonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_3544023_9	392499.Swit_1412	2.222e-21	102.0	COG3791@1|root,COG3791@2|Bacteria,1N6S5@1224|Proteobacteria,2UG0P@28211|Alphaproteobacteria,2KD97@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_3570365_2	290397.Adeh_2826	2.488e-36	159.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,42QEH@68525|delta/epsilon subdivisions,2WKVC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Response regulator, receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ,Response_reg
CMS3_k127_3570365_1	404589.Anae109_3968	3.034e-89	315.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,42PA6@68525|delta/epsilon subdivisions,2WIIY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
CMS3_k127_3570365_3	1158292.JPOE01000005_gene1233	6.018e-25	117.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2VMT6@28216|Betaproteobacteria,1KNJZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Flp pilus assembly protein RcpC/CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS3_k127_3570365_5	1101188.KI912155_gene825	9.984e-05	53.0	COG4961@1|root,COG4961@2|Bacteria,2GWMA@201174|Actinobacteria	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS3_k127_3570365_4	880072.Desac_0791	9.285e-10	67.0	COG4960@1|root,COG4960@2|Bacteria,1N7J0@1224|Proteobacteria	1224|Proteobacteria	OU	Peptidase A24A, prepilin type IV	cpaA1	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
CMS3_k127_3570365_6	1123270.ATUR01000002_gene2514	0.0006574	46.0	COG3847@1|root,COG3847@2|Bacteria,1NNS6@1224|Proteobacteria,2UMCC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Pilus assembly protein	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS3_k127_3570365_0	502025.Hoch_6638	2.52e-135	453.0	COG1874@1|root,COG1874@2|Bacteria,1NDQP@1224|Proteobacteria,4388G@68525|delta/epsilon subdivisions,2X3I5@28221|Deltaproteobacteria,2YW75@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 35 family	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
CMS3_k127_3594867_1	1144275.COCOR_03299	5.968e-63	243.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_3594867_0	502025.Hoch_5408	2.157e-304	956.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YTZK@29|Myxococcales	28221|Deltaproteobacteria	CE	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
CMS3_k127_3594867_2	502025.Hoch_1497	2.498e-28	132.0	COG1524@1|root,COG1524@2|Bacteria,1MYH0@1224|Proteobacteria,42QJN@68525|delta/epsilon subdivisions,2WXWZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_3623773_1	502025.Hoch_1923	4.202e-47	174.0	COG0204@1|root,COG0204@2|Bacteria,1PZS9@1224|Proteobacteria,434JR@68525|delta/epsilon subdivisions,2WYX1@28221|Deltaproteobacteria,2Z0U7@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_3623773_0	886293.Sinac_1156	2.374e-190	618.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_3629678_1	1382306.JNIM01000001_gene2872	1.31e-26	122.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS3_k127_3629678_0	1254432.SCE1572_20490	1.917e-77	276.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,42VQH@68525|delta/epsilon subdivisions,2WRIC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_3669750_11	1254432.SCE1572_30850	4.346e-05	49.0	COG1858@1|root,COG1858@2|Bacteria,1Q3KS@1224|Proteobacteria,439DX@68525|delta/epsilon subdivisions,2X4NW@28221|Deltaproteobacteria,2YZBK@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3669750_8	448385.sce1024	6.369e-15	82.0	COG2863@1|root,COG2863@2|Bacteria,1NDS5@1224|Proteobacteria,43CTZ@68525|delta/epsilon subdivisions,2X81J@28221|Deltaproteobacteria,2YVKA@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3669750_5	1123060.JONP01000013_gene4049	7.673e-55	205.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,2JWAD@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_3669750_3	467200.ACFA01000925_gene1413	5.134e-82	282.0	COG4221@1|root,COG4221@2|Bacteria,2GP16@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3669750_1	497964.CfE428DRAFT_2211	9.401e-125	420.0	COG3882@1|root,COG3882@2|Bacteria,46TK1@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	NIF
CMS3_k127_3669750_12	987059.RBXJA2T_13714	9.246e-05	55.0	COG0236@1|root,COG0236@2|Bacteria,1NHXU@1224|Proteobacteria,2VY0K@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_3669750_10	469381.Dpep_0589	7.405e-07	59.0	COG0346@1|root,COG0346@2|Bacteria,3TAXT@508458|Synergistetes	508458|Synergistetes	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS3_k127_3669750_4	706587.Desti_3926	2.793e-56	216.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2MRQ4@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3669750_2	1304888.ATWF01000002_gene340	1.464e-85	315.0	COG1033@1|root,COG1033@2|Bacteria,2GFIN@200930|Deferribacteres	200930|Deferribacteres	K	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_3669750_6	644282.Deba_2835	1.632e-51	192.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42QPE@68525|delta/epsilon subdivisions,2WN39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_3669750_9	344747.PM8797T_24301	3.128e-12	78.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
CMS3_k127_3669750_7	1121396.KB892946_gene2895	1.047e-26	129.0	COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,42PXB@68525|delta/epsilon subdivisions,2WJKN@28221|Deltaproteobacteria,2MJ1J@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
CMS3_k127_3669750_0	1254432.SCE1572_06465	3.828e-159	533.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_367614_2	502025.Hoch_5841	1.864e-173	550.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2YUFJ@29|Myxococcales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS3_k127_367614_5	502025.Hoch_5842	1.305e-66	236.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2YV51@29|Myxococcales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS3_k127_367614_4	502025.Hoch_5843	2.471e-73	258.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS3_k127_367614_3	502025.Hoch_5852	6.799e-108	364.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K10108,ko:K10117,ko:K15770	ko02010,ko02030,map02010,map02030	M00194,M00196,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
CMS3_k127_367614_0	502025.Hoch_5853	3.985e-189	608.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	zraS	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02482,ko:K07709,ko:K10125	ko02020,map02020	M00499,M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1,sCache_3_2
CMS3_k127_367614_1	502025.Hoch_5854	4.07e-179	599.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	nla28	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_3690311_0	502025.Hoch_3149	3.672e-205	663.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YWIW@29|Myxococcales	28221|Deltaproteobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CMS3_k127_3712001_0	502025.Hoch_0467	3.936e-267	853.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2Z1W9@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
CMS3_k127_3712001_3	661478.OP10G_3381	5.354e-50	189.0	COG2720@1|root,COG2720@2|Bacteria	2|Bacteria	V	VanW like protein	vanW	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	VanW
CMS3_k127_3712001_10	1160718.SU9_04041	2.81e-07	63.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_11,Methyltransf_2,Methyltransf_25,Methyltransf_31
CMS3_k127_3712001_2	509190.Cseg_2337	2.193e-66	241.0	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,2TUDJ@28211|Alphaproteobacteria,2KGRX@204458|Caulobacterales	204458|Caulobacterales	I	3-phytase	-	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
CMS3_k127_3712001_8	479437.Elen_2651	1.699e-14	85.0	COG0641@1|root,COG0641@2|Bacteria,2I6AC@201174|Actinobacteria,4CVIZ@84998|Coriobacteriia	84998|Coriobacteriia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_3712001_9	1123320.KB889684_gene2351	7.856e-14	80.0	COG1309@1|root,COG1309@2|Bacteria,2GKYA@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3712001_5	1242864.D187_008834	4.332e-39	154.0	COG3794@1|root,COG3794@2|Bacteria,1Q2EH@1224|Proteobacteria,43807@68525|delta/epsilon subdivisions,2X3A8@28221|Deltaproteobacteria,2YV38@29|Myxococcales	28221|Deltaproteobacteria	C	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_3712001_1	1192034.CAP_0212	5.831e-114	381.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria,2Z3J1@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_3714712_1	215803.DB30_5754	5.956e-97	323.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS3_k127_3714712_3	502025.Hoch_4709	4.458e-45	172.0	2EQTB@1|root,33ID2@2|Bacteria,1P3AG@1224|Proteobacteria,4387H@68525|delta/epsilon subdivisions,2X3HD@28221|Deltaproteobacteria,2YW3P@29|Myxococcales	28221|Deltaproteobacteria	S	Lytic polysaccharide mono-oxygenase, cellulose-degrading	-	-	-	-	-	-	-	-	-	-	-	-	LPMO_10
CMS3_k127_3714712_0	1192034.CAP_1523	0.0	1045.0	COG0515@1|root,COG2909@1|root,COG0515@2|Bacteria,COG2909@2|Bacteria,1QA6R@1224|Proteobacteria,4393M@68525|delta/epsilon subdivisions,2X49J@28221|Deltaproteobacteria,2YYJG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_3714712_7	411684.HPDFL43_14972	9.963e-26	124.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,43KPD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS3_k127_3714712_6	1200567.JNKD01000027_gene1456	2.202e-26	128.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS3_k127_3714712_9	1150621.SMUL_2431	1.396e-11	76.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	3.1.1.32,3.1.1.4	ko:K01058,ko:K07126	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	DUF900,Sel1
CMS3_k127_3714712_2	745310.G432_01630	2.702e-79	294.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TV8M@28211|Alphaproteobacteria,2K1QN@204457|Sphingomonadales	204457|Sphingomonadales	C	Luciferase family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_3714712_4	243159.AFE_2322	1.038e-43	182.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,2NC2R@225057|Acidithiobacillales	225057|Acidithiobacillales	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_3714712_8	1056816.JAFQ01000003_gene7183	1.326e-14	83.0	COG1633@1|root,COG1633@2|Bacteria,2GN5C@201174|Actinobacteria,4FW7A@85025|Nocardiaceae	201174|Actinobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3727924_0	502025.Hoch_6714	1.121e-161	514.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS3_k127_3727924_1	1236959.BAMT01000005_gene153	6.543e-85	289.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,2KKMZ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS3_k127_3727924_2	1538295.JY96_19365	9.874e-65	242.0	COG3315@1|root,COG3315@2|Bacteria,1RCET@1224|Proteobacteria	1224|Proteobacteria	Q	COG3315 O-Methyltransferase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_373774_51	1370125.AUWT01000036_gene1539	0.0001658	50.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
CMS3_k127_373774_28	1120971.AUCA01000078_gene1864	1.274e-64	240.0	COG3173@1|root,COG3173@2|Bacteria,1V2AK@1239|Firmicutes,4HFXB@91061|Bacilli,279TH@186823|Alicyclobacillaceae	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_373774_44	483219.LILAB_33115	6.013e-22	111.0	COG1506@1|root,COG2885@1|root,COG1506@2|Bacteria,COG2885@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_373774_36	1192034.CAP_2122	3.122e-44	181.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
CMS3_k127_373774_46	1396141.BATP01000034_gene4198	8.091e-13	81.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
CMS3_k127_373774_37	1177179.A11A3_12183	2.98e-39	169.0	COG0730@1|root,COG0730@2|Bacteria,1P10Q@1224|Proteobacteria,1RY3A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_373774_35	411464.DESPIG_00919	1.131e-45	185.0	COG5653@1|root,COG5653@2|Bacteria,1NN79@1224|Proteobacteria,42ZVH@68525|delta/epsilon subdivisions,2WVIB@28221|Deltaproteobacteria,2MADX@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_373774_12	502025.Hoch_1917	6.512e-129	425.0	COG0833@1|root,COG0833@2|Bacteria,1QU71@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	-	-	-	ko:K03294,ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.5	-	-	AA_permease_2
CMS3_k127_373774_23	935863.AWZR01000007_gene259	2.391e-77	269.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_373774_0	886293.Sinac_1156	1.068e-280	908.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_373774_43	1232410.KI421427_gene1287	5.133e-24	104.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_373774_25	1192034.CAP_2321	1.234e-72	262.0	COG4935@1|root,COG4935@2|Bacteria,1Q3W5@1224|Proteobacteria,4343N@68525|delta/epsilon subdivisions,2X525@28221|Deltaproteobacteria,2Z009@29|Myxococcales	28221|Deltaproteobacteria	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein
CMS3_k127_373774_6	448385.sce6976	3.13e-171	563.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
CMS3_k127_373774_8	1254432.SCE1572_30850	3.002e-168	550.0	COG1858@1|root,COG1858@2|Bacteria,1Q3KS@1224|Proteobacteria,439DX@68525|delta/epsilon subdivisions,2X4NW@28221|Deltaproteobacteria,2YZBK@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_373774_49	926560.KE387023_gene2903	1.444e-05	57.0	COG3895@1|root,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
CMS3_k127_373774_41	247634.GPB2148_301	1.936e-28	132.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
CMS3_k127_373774_27	502025.Hoch_1817	6.9e-65	246.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_373774_16	335543.Sfum_0467	6.904e-116	397.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,2MQ4I@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_373774_48	445974.CLORAM_01624	1.718e-08	59.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,3VQC7@526524|Erysipelotrichia	526524|Erysipelotrichia	CO	Antioxidant, AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
CMS3_k127_373774_21	502025.Hoch_5015	4.877e-79	279.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_373774_4	448385.sce2889	4.911e-205	650.0	COG0274@1|root,COG0274@2|Bacteria,1R45J@1224|Proteobacteria,438PK@68525|delta/epsilon subdivisions,2X8TQ@28221|Deltaproteobacteria,2YXFJ@29|Myxococcales	28221|Deltaproteobacteria	F	D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit	kamD	-	5.4.3.3	ko:K01844	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	Lys-AminoMut_A
CMS3_k127_373774_19	1254432.SCE1572_17630	2.111e-85	290.0	COG2185@1|root,COG2185@2|Bacteria,1R6CI@1224|Proteobacteria,43CUR@68525|delta/epsilon subdivisions,2X82G@28221|Deltaproteobacteria,2YYB5@29|Myxococcales	28221|Deltaproteobacteria	I	Dimerisation domain of d-ornithine 4,5-aminomutase	-	-	5.4.3.3	ko:K18011	ko00310,map00310	-	R02852,R03275	RC00719	ko00000,ko00001,ko01000	-	-	-	B12-binding,OAM_dimer
CMS3_k127_373774_10	448385.sce6192	1.583e-141	472.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,42QYC@68525|delta/epsilon subdivisions,2WN66@28221|Deltaproteobacteria,2Z2W3@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Kce	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	4HBT,BKACE
CMS3_k127_373774_40	502025.Hoch_5014	3.059e-30	123.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_373774_50	1216976.AX27061_5520	0.0001618	50.0	COG1595@1|root,COG1595@2|Bacteria,1N1F5@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	hasI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_373774_30	502025.Hoch_4169	2.383e-61	216.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria,2YVPM@29|Myxococcales	28221|Deltaproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
CMS3_k127_373774_26	502025.Hoch_2507	5.275e-72	269.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_373774_5	502025.Hoch_4168	1.776e-177	579.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,42V1G@68525|delta/epsilon subdivisions,2WRCZ@28221|Deltaproteobacteria,2YWCA@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_373774_42	56780.SYN_02874	1.042e-26	121.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,42M1U@68525|delta/epsilon subdivisions,2WKK5@28221|Deltaproteobacteria,2MRYB@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	pfkB family carbohydrate kinase	-	-	2.7.1.15,2.7.1.4	ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_373774_18	243231.GSU2502	3.333e-106	379.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_373774_14	580332.Slit_2174	1.252e-117	407.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VKNA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	aidB_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
CMS3_k127_373774_24	502025.Hoch_4167	1.747e-76	261.0	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_373774_38	502025.Hoch_4166	5.274e-32	140.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_373774_33	502025.Hoch_4165	1.166e-54	213.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_373774_20	502025.Hoch_4568	1.869e-80	274.0	COG0235@1|root,COG0235@2|Bacteria,1N2XS@1224|Proteobacteria,42VFM@68525|delta/epsilon subdivisions,2WS66@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS3_k127_373774_9	1183438.GKIL_1654	4.641e-151	504.0	COG0659@1|root,COG0659@2|Bacteria,1G1CM@1117|Cyanobacteria	1117|Cyanobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
CMS3_k127_373774_32	448385.sce3073	6.655e-56	218.0	COG4402@1|root,COG4402@2|Bacteria,1QA5C@1224|Proteobacteria,434UU@68525|delta/epsilon subdivisions,2WZ5W@28221|Deltaproteobacteria,2Z1E4@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_373774_11	502025.Hoch_4162	3.801e-132	424.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42RNB@68525|delta/epsilon subdivisions,2WQ81@28221|Deltaproteobacteria,2YTTJ@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_373774_17	502025.Hoch_4161	1.542e-115	397.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42QW6@68525|delta/epsilon subdivisions,2WPZA@28221|Deltaproteobacteria,2YVC6@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	-	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS3_k127_373774_13	502025.Hoch_4160	1.284e-124	430.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2YUFD@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_373774_29	502025.Hoch_4158	8.236e-64	243.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,2YVCE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
CMS3_k127_373774_22	215803.DB30_8353	9.818e-78	281.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2YWNN@29|Myxococcales	28221|Deltaproteobacteria	M	ATP-grasp domain	ddlB1	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_373774_39	246197.MXAN_5952	8.475e-32	131.0	COG0454@1|root,COG0456@2|Bacteria,1NEWG@1224|Proteobacteria,42VG1@68525|delta/epsilon subdivisions,2WRCC@28221|Deltaproteobacteria,2Z1UQ@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS3_k127_373774_2	502025.Hoch_4810	1.929e-239	775.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,2YUKX@29|Myxococcales	28221|Deltaproteobacteria	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_373774_7	502025.Hoch_3904	8.646e-169	567.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,42NVH@68525|delta/epsilon subdivisions,2WJN9@28221|Deltaproteobacteria,2YU67@29|Myxococcales	28221|Deltaproteobacteria	F	imidazolonepropionase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_373774_1	292459.STH3193	9.298e-254	793.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS3_k127_373774_3	502025.Hoch_3903	5.779e-220	692.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria,2YUFR@29|Myxococcales	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CMS3_k127_373774_15	502025.Hoch_3902	2.86e-116	411.0	COG0457@1|root,COG0457@2|Bacteria,1QA96@1224|Proteobacteria,43DYT@68525|delta/epsilon subdivisions,2X92B@28221|Deltaproteobacteria,2Z1IW@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_37702_3	1227487.C474_03200	1.079e-30	128.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_37702_0	1122176.KB903551_gene4256	1.519e-71	266.0	COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,1IU97@117747|Sphingobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_37702_4	391625.PPSIR1_09520	2.56e-21	109.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_37702_2	283942.IL2442	2.188e-36	147.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,2QGJQ@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	MgtC family	mgtC	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_37702_1	404589.Anae109_3872	8.654e-66	237.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_380056_6	1254432.SCE1572_51470	2.789e-55	196.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2Z08H@29|Myxococcales	28221|Deltaproteobacteria	C	Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS3_k127_380056_7	502025.Hoch_2185	2.084e-44	164.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,431E6@68525|delta/epsilon subdivisions,2WWGA@28221|Deltaproteobacteria,2YVXB@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS3_k127_380056_0	502025.Hoch_2184	1.979e-179	575.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2YU4J@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_380056_12	1120999.JONM01000008_gene2004	8.425e-27	127.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,2KRQ5@206351|Neisseriales	206351|Neisseriales	L	nudix family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_380056_14	399739.Pmen_3657	6.438e-14	84.0	2BH9V@1|root,32BBC@2|Bacteria,1QIJS@1224|Proteobacteria,1TGET@1236|Gammaproteobacteria,1YDVW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_380056_5	502025.Hoch_3934	6.214e-75	274.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2Z2Z1@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS3_k127_380056_10	502025.Hoch_3935	4.722e-32	138.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2Z1N4@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_380056_1	502025.Hoch_3939	1.559e-174	554.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2YU37@29|Myxococcales	28221|Deltaproteobacteria	C	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
CMS3_k127_380056_2	502025.Hoch_3940	4.021e-110	387.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,42PNR@68525|delta/epsilon subdivisions,2WK3I@28221|Deltaproteobacteria,2YV9T@29|Myxococcales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF1730)	yjeS	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
CMS3_k127_380056_13	502025.Hoch_3207	4.978e-20	102.0	COG2010@1|root,COG2010@2|Bacteria,1QY9A@1224|Proteobacteria	1224|Proteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_380056_9	502025.Hoch_3614	1.257e-36	158.0	COG1196@1|root,COG1716@1|root,COG5164@1|root,COG1196@2|Bacteria,COG1716@2|Bacteria,COG5164@2|Bacteria	2|Bacteria	K	cell wall organization	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF11,FHA,HATPase_c,HTH_8,HisKA,PAS_3,Response_reg,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_380056_3	502025.Hoch_3218	1.027e-80	293.0	COG1451@1|root,COG1451@2|Bacteria,1P1X1@1224|Proteobacteria,4314C@68525|delta/epsilon subdivisions,2X3BB@28221|Deltaproteobacteria,2YV83@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_380056_11	502025.Hoch_4728	7.976e-28	116.0	COG3695@1|root,COG3695@2|Bacteria,1PZ1K@1224|Proteobacteria,42WV5@68525|delta/epsilon subdivisions,2WT08@28221|Deltaproteobacteria,2YVVE@29|Myxococcales	28221|Deltaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
CMS3_k127_380056_4	502025.Hoch_4729	5.03e-76	269.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1RGUX@1224|Proteobacteria,437BZ@68525|delta/epsilon subdivisions,2WQNB@28221|Deltaproteobacteria,2YVJC@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS3_k127_381601_2	378806.STAUR_7238	4.673e-108	369.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_381601_5	925775.XVE_4387	7.682e-23	113.0	COG4219@1|root,COG4219@2|Bacteria,1R3YH@1224|Proteobacteria,1RX87@1236|Gammaproteobacteria,1XCNJ@135614|Xanthomonadales	135614|Xanthomonadales	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS3_k127_381601_4	1297742.A176_01867	7.913e-36	140.0	COG3682@1|root,COG3682@2|Bacteria,1N3JW@1224|Proteobacteria,434IN@68525|delta/epsilon subdivisions,2WYVW@28221|Deltaproteobacteria,2Z0RS@29|Myxococcales	28221|Deltaproteobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_381601_1	1297742.A176_04476	7.405e-114	401.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_381601_6	1120983.KB894572_gene3153	1.184e-17	87.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,1JQ8N@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_381601_3	1254432.SCE1572_19565	1.412e-103	351.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,42UUC@68525|delta/epsilon subdivisions,2WQFQ@28221|Deltaproteobacteria,2YZP1@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS3_k127_381601_7	388051.AUFE01000063_gene5305	1.538e-10	70.0	COG1633@1|root,COG1633@2|Bacteria,1RGZG@1224|Proteobacteria,2VSVM@28216|Betaproteobacteria,1K16X@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
CMS3_k127_381601_0	502025.Hoch_1930	3.738e-155	499.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2YU3N@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_3831533_1	1254432.SCE1572_43295	3.286e-100	336.0	COG2010@1|root,COG2010@2|Bacteria,1QX4J@1224|Proteobacteria,437VA@68525|delta/epsilon subdivisions,2X34V@28221|Deltaproteobacteria,2YUNT@29|Myxococcales	28221|Deltaproteobacteria	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,Cu2_monooxygen
CMS3_k127_3831533_3	313596.RB2501_06330	5.558e-05	55.0	COG3637@1|root,COG3637@2|Bacteria,4NW7Z@976|Bacteroidetes,1I5D8@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS3_k127_3831533_0	502025.Hoch_5961	6.299e-136	462.0	COG2304@1|root,COG2304@2|Bacteria,1QANI@1224|Proteobacteria,4356Z@68525|delta/epsilon subdivisions,2X96C@28221|Deltaproteobacteria,2Z271@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS3_k127_3831533_2	502025.Hoch_5960	3.107e-34	136.0	COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YUHG@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_383441_5	661478.OP10G_4121	1.53e-109	376.0	COG0514@1|root,COG0514@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase (RecQ)	recQ	GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008270,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0017117,GO:0030894,GO:0032392,GO:0032508,GO:0032991,GO:0032993,GO:0033202,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043142,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1904949	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_383441_2	1192034.CAP_3040	2.317e-153	532.0	COG1360@1|root,COG5316@1|root,COG1360@2|Bacteria,COG5316@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF4139,DotU,OmpA
CMS3_k127_383441_14	1120948.KB903240_gene4091	4.334e-39	165.0	COG0500@1|root,COG2226@2|Bacteria,2INQ9@201174|Actinobacteria,4EEK7@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_383441_16	1280676.AUJO01000027_gene3054	4.661e-16	93.0	COG0584@1|root,COG0584@2|Bacteria,1V6FX@1239|Firmicutes,25D50@186801|Clostridia,4C1SF@830|Butyrivibrio	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
CMS3_k127_383441_13	215803.DB30_3297	2.589e-43	181.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,439KT@68525|delta/epsilon subdivisions,2X4XM@28221|Deltaproteobacteria,2YZT0@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_383441_19	1519464.HY22_02940	0.0003509	53.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PQQ_2,TPR_8
CMS3_k127_383441_4	1254432.SCE1572_02795	1.171e-113	385.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_383441_6	378806.STAUR_7238	1.59e-102	357.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_383441_11	502025.Hoch_4659	5.49e-57	211.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YYKC@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_383441_3	502025.Hoch_4455	4.847e-148	486.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2YUWB@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS3_k127_383441_9	502025.Hoch_6401	2.444e-74	259.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	ko:K03496,ko:K22491	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	B12-binding_2,DUF3967,HTH_17,MerR_1
CMS3_k127_383441_7	404589.Anae109_3008	4.286e-92	312.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2YW8F@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
CMS3_k127_383441_1	314230.DSM3645_25517	4.053e-166	550.0	COG0415@1|root,COG0415@2|Bacteria,2IXWI@203682|Planctomycetes	203682|Planctomycetes	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
CMS3_k127_383441_0	502025.Hoch_6275	2.763e-166	550.0	COG3303@1|root,COG3303@2|Bacteria,1NT38@1224|Proteobacteria,43CCP@68525|delta/epsilon subdivisions,2X7NK@28221|Deltaproteobacteria,2YZY2@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_383441_12	290397.Adeh_3077	5.81e-48	187.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
CMS3_k127_383441_10	502025.Hoch_6277	1.912e-64	243.0	COG3005@1|root,COG3005@2|Bacteria,1Q9NJ@1224|Proteobacteria,434HC@68525|delta/epsilon subdivisions,2WYUP@28221|Deltaproteobacteria,2Z0NR@29|Myxococcales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
CMS3_k127_3842104_4	502025.Hoch_5869	9.388e-08	63.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
CMS3_k127_3842104_1	1254432.SCE1572_34785	7.777e-31	134.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
CMS3_k127_3842104_0	1254432.SCE1572_18890	5.257e-142	478.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CMS3_k127_3842104_6	1094508.Tsac_0303	7.695e-07	63.0	COG4733@1|root,COG4733@2|Bacteria,1TT7S@1239|Firmicutes,24EIJ@186801|Clostridia,42FI7@68295|Thermoanaerobacterales	186801|Clostridia	S	Cell surface receptor IPT TIG	-	-	-	-	-	-	-	-	-	-	-	-	TIG,fn3
CMS3_k127_3842679_3	1254432.SCE1572_03630	2.788e-16	89.0	COG3391@1|root,COG3391@2|Bacteria,1R0BE@1224|Proteobacteria,43CTP@68525|delta/epsilon subdivisions,2X817@28221|Deltaproteobacteria,2Z05E@29|Myxococcales	28221|Deltaproteobacteria	E	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
CMS3_k127_3842679_0	886293.Sinac_1156	6.905e-234	768.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_3842679_1	382464.ABSI01000010_gene3794	1.456e-34	153.0	COG4888@1|root,COG4888@2|Bacteria,46UDG@74201|Verrucomicrobia	2|Bacteria	O	PFAM ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_3842679_2	886293.Sinac_2706	7.268e-32	140.0	COG3118@1|root,COG3118@2|Bacteria,2J53R@203682|Planctomycetes	203682|Planctomycetes	O	PFAM ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_3873333_2	502025.Hoch_1789	1.838e-140	450.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WK79@28221|Deltaproteobacteria,2YV9G@29|Myxococcales	28221|Deltaproteobacteria	H	aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_3873333_14	1254432.SCE1572_20660	6.261e-29	129.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_3873333_5	502025.Hoch_4453	2.456e-86	302.0	2AGK9@1|root,316TF@2|Bacteria,1PXZN@1224|Proteobacteria,434ZD@68525|delta/epsilon subdivisions,2WZA6@28221|Deltaproteobacteria,2Z1PC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3873333_13	1487953.JMKF01000044_gene2999	2.539e-33	134.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1HCM2@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS3_k127_3873333_7	1242864.D187_006454	9.617e-66	235.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,4386C@68525|delta/epsilon subdivisions,2X3G9@28221|Deltaproteobacteria,2YVYS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3873333_10	502025.Hoch_6559	8.428e-55	212.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TMP@68525|delta/epsilon subdivisions,2WR9C@28221|Deltaproteobacteria,2YV89@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_3873333_4	1254432.SCE1572_20990	2.955e-110	364.0	COG0604@1|root,COG0604@2|Bacteria,1R2DZ@1224|Proteobacteria,43DM8@68525|delta/epsilon subdivisions,2X65T@28221|Deltaproteobacteria,2Z39E@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3873333_15	378806.STAUR_1368	3.202e-24	110.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS3_k127_3873333_12	448385.sce9005	5.763e-36	150.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Thioredoxin_4,VKOR
CMS3_k127_3873333_6	1235798.C817_01111	1.601e-67	246.0	COG1250@1|root,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
CMS3_k127_3873333_1	59538.XP_005965360.1	3.662e-150	489.0	KOG1406@1|root,KOG1406@2759|Eukaryota,38CKQ@33154|Opisthokonta,3BDZX@33208|Metazoa,3CUCP@33213|Bilateria,483XX@7711|Chordata,48ZBY@7742|Vertebrata,3J60I@40674|Mammalia	2759|Eukaryota	I	Non-specific lipid-transfer protein	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_3873333_17	502025.Hoch_4589	2.278e-05	56.0	COG0745@1|root,COG3215@1|root,COG0745@2|Bacteria,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_3873333_9	324602.Caur_0022	3.085e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,377BM@32061|Chloroflexia	32061|Chloroflexia	K	Sigma-70, region 4 type 2	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_3873333_11	326427.Cagg_3669	8.081e-41	168.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G6F0@200795|Chloroflexi,377HR@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
CMS3_k127_3873333_8	2002.JOEQ01000023_gene1200	1.707e-63	227.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria,4EI20@85012|Streptosporangiales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3873333_0	329726.AM1_5955	0.0	1291.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS3_k127_3873333_3	391625.PPSIR1_00610	1.328e-139	462.0	COG0402@1|root,COG5184@1|root,COG0402@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,RCC1_2
CMS3_k127_3873333_16	1411123.JQNH01000001_gene2225	2.033e-13	72.0	COG2010@1|root,COG2010@2|Bacteria,1N0EF@1224|Proteobacteria,2U91T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_387476_7	1116472.MGMO_92c00470	0.0001884	47.0	2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,1XFPB@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CMS3_k127_387476_4	502025.Hoch_5696	8.612e-22	110.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria	1224|Proteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CMS3_k127_387476_6	319225.Plut_1571	1.129e-06	53.0	2E3QA@1|root,32YN8@2|Bacteria,1FFJG@1090|Chlorobi	1090|Chlorobi	M	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CMS3_k127_387476_8	1227453.C444_10259	0.0003977	53.0	COG1653@1|root,arCOG00151@2157|Archaea,2Y2AY@28890|Euryarchaeota,23Z4Y@183963|Halobacteria	183963|Halobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_387476_0	671143.DAMO_0613	4.282e-76	270.0	COG0535@1|root,COG0535@2|Bacteria,2NRPX@2323|unclassified Bacteria	2|Bacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_387476_1	1192034.CAP_4236	1.453e-51	195.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_387476_3	247490.KSU1_C0840	3.464e-45	174.0	COG2010@1|root,COG2010@2|Bacteria,2IZC1@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_387476_2	1122604.JONR01000007_gene2936	5.367e-47	183.0	28P4Q@1|root,2ZBZV@2|Bacteria,1RA48@1224|Proteobacteria,1S347@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_387476_5	1134474.O59_000466	4.135e-07	56.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3885210_0	926560.KE387023_gene1240	2.173e-80	287.0	COG0318@1|root,COG0318@2|Bacteria,1WM4M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CMS3_k127_3885210_1	1042163.BRLA_c023900	3.958e-72	271.0	COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,4HX2Z@91061|Bacilli	91061|Bacilli	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
CMS3_k127_3885210_2	504487.JCM19302_2612	1.984e-05	53.0	COG1033@1|root,COG1033@2|Bacteria,4NKTD@976|Bacteroidetes	976|Bacteroidetes	S	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_389747_6	1265313.HRUBRA_01348	1.607e-40	158.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
CMS3_k127_389747_8	1385935.N836_32595	1.973e-30	127.0	COG4902@1|root,COG4902@2|Bacteria,1G6BZ@1117|Cyanobacteria,1HBNX@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
CMS3_k127_389747_14	266117.Rxyl_1973	5.976e-13	77.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CSAX@84995|Rubrobacteria	84995|Rubrobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_389747_12	84531.JMTZ01000051_gene928	3.72e-19	100.0	2CGEX@1|root,32Z75@2|Bacteria,1PAQV@1224|Proteobacteria,1T6YK@1236|Gammaproteobacteria,1X8F2@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS3_k127_389747_9	502025.Hoch_4274	1.186e-28	130.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	-	ko:K02487,ko:K06596,ko:K07576	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	Autotransporter,Biotin_lipoyl,T2SSE_N
CMS3_k127_389747_5	313628.LNTAR_08784	1.198e-80	284.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	glp	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
CMS3_k127_389747_7	1487953.JMKF01000045_gene2926	7.251e-32	145.0	COG1073@1|root,COG1073@2|Bacteria,1GBEW@1117|Cyanobacteria	1117|Cyanobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_389747_16	502025.Hoch_5168	7.721e-12	69.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA_1	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_389747_13	1117647.M5M_01292	3.7e-16	91.0	2BXHT@1|root,2ZPUR@2|Bacteria,1P5T2@1224|Proteobacteria,1SUZ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_389747_3	502025.Hoch_0105	2.748e-115	386.0	COG2204@1|root,COG2204@2|Bacteria,1R0E3@1224|Proteobacteria,43CWJ@68525|delta/epsilon subdivisions,2WSIM@28221|Deltaproteobacteria,2YW6V@29|Myxococcales	2|Bacteria	T	response regulator	-	-	-	ko:K02282,ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022,ko02035,ko02044	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HTH_8,HisKA,PAS_7,PAS_9,Response_reg,Sigma54_activ_2,V4R,XylR_N
CMS3_k127_389747_2	502025.Hoch_0104	9.578e-116	381.0	2EF8C@1|root,3391B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_389747_4	404589.Anae109_3359	2.28e-83	311.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_4,Sigma54_activat
CMS3_k127_389747_15	269799.Gmet_0878	7.06e-12	73.0	COG2062@1|root,COG2062@2|Bacteria,1NH0V@1224|Proteobacteria,42WVA@68525|delta/epsilon subdivisions,2WT6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS3_k127_389747_0	378806.STAUR_8179	1.512e-208	666.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria,42UE9@68525|delta/epsilon subdivisions,2WR5R@28221|Deltaproteobacteria,2YXK9@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
CMS3_k127_389747_10	472759.Nhal_2917	2.541e-21	97.0	arCOG11477@1|root,32TJG@2|Bacteria,1MYXX@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_389747_1	640511.BC1002_5570	5.943e-125	437.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
CMS3_k127_389747_11	448385.sce2073	3.173e-19	96.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2Z01S@29|Myxococcales	28221|Deltaproteobacteria	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
CMS3_k127_3899547_16	448385.sce1653	3.458e-47	190.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1RATK@1224|Proteobacteria,42R5C@68525|delta/epsilon subdivisions,2WMZP@28221|Deltaproteobacteria,2YW9T@29|Myxococcales	28221|Deltaproteobacteria	T	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE_N,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_3899547_8	502025.Hoch_4522	3.371e-90	298.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2YVAI@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, CarD family	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
CMS3_k127_3899547_25	694429.Pyrfu_0133	6.109e-11	64.0	COG2110@1|root,arCOG04225@2157|Archaea,2XQEQ@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_3899547_20	224324.aq_987	9.566e-21	95.0	COG2110@1|root,COG2110@2|Bacteria,2G45I@200783|Aquificae	200783|Aquificae	S	Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_3899547_24	5147.XP_003343056.1	3.603e-11	70.0	COG0838@1|root,KOG4662@2759|Eukaryota	2759|Eukaryota	C	NADH dehydrogenase (quinone) activity	ND3	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031960,GO:0031966,GO:0031967,GO:0031975,GO:0032870,GO:0032981,GO:0032991,GO:0033108,GO:0033993,GO:0034622,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048545,GO:0050136,GO:0050896,GO:0051384,GO:0051716,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0070887,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K03880	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q4
CMS3_k127_3899547_10	502025.Hoch_4520	8.16e-88	299.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WN9U@28221|Deltaproteobacteria,2YUX6@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3354	Oxidored_q6
CMS3_k127_3899547_14	502025.Hoch_4519	2.57e-64	223.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2WQB1@28221|Deltaproteobacteria,2YVJM@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
CMS3_k127_3899547_1	1254432.SCE1572_03660	1.838e-153	502.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YU4Q@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
CMS3_k127_3899547_0	502025.Hoch_4517	1.896e-235	739.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WKMJ@28221|Deltaproteobacteria,2YU8F@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
CMS3_k127_3899547_3	502025.Hoch_4516	1.124e-150	498.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YUQD@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS3_k127_3899547_12	502025.Hoch_4515	7.222e-77	280.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
CMS3_k127_3899547_18	1242864.D187_006455	1.397e-25	122.0	2BK7J@1|root,32EMD@2|Bacteria,1QB42@1224|Proteobacteria,43E56@68525|delta/epsilon subdivisions,2WZRQ@28221|Deltaproteobacteria,2Z2M1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3899547_19	926562.Oweho_2181	1.654e-23	109.0	2AFQ6@1|root,315RZ@2|Bacteria,4PJXZ@976|Bacteroidetes,1IMQA@117743|Flavobacteriia,2PB7X@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CMS3_k127_3899547_27	1283300.ATXB01000002_gene3018	0.0008466	53.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1XFEG@135618|Methylococcales	135618|Methylococcales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
CMS3_k127_3899547_22	345341.KUTG_01472	2.162e-18	93.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria,4E4SF@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3899547_9	502025.Hoch_4661	2.23e-88	301.0	COG1266@1|root,COG1266@2|Bacteria,1R5BW@1224|Proteobacteria,434JF@68525|delta/epsilon subdivisions,2WYWP@28221|Deltaproteobacteria,2Z0TD@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_3899547_4	1323663.AROI01000014_gene118	1.597e-150	490.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	iEC042_1314.EC042_2616	tRNA-synt_1c
CMS3_k127_3899547_11	502025.Hoch_4663	2.061e-82	288.0	COG5549@1|root,COG5549@2|Bacteria,1PBXR@1224|Proteobacteria,43864@68525|delta/epsilon subdivisions,2X0VV@28221|Deltaproteobacteria,2YVXH@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
CMS3_k127_3899547_7	502025.Hoch_4665	2.456e-107	352.0	COG0745@1|root,COG0745@2|Bacteria,1PG0S@1224|Proteobacteria,4391F@68525|delta/epsilon subdivisions,2X46V@28221|Deltaproteobacteria,2YYDF@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3899547_2	502025.Hoch_4666	9.624e-152	526.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,43ARK@68525|delta/epsilon subdivisions,2X65I@28221|Deltaproteobacteria,2YWWX@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_3899547_13	502025.Hoch_4667	2.286e-69	249.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2YYZA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3899547_6	502025.Hoch_4668	1.331e-107	362.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	fgrL	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS3_k127_3899547_15	1123487.KB892866_gene1744	6.924e-51	195.0	COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,2VJQD@28216|Betaproteobacteria,2KY8Q@206389|Rhodocyclales	206389|Rhodocyclales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CMS3_k127_3899547_5	502025.Hoch_4669	1.903e-133	446.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_3899547_17	502025.Hoch_4670	5.458e-32	140.0	29YZ3@1|root,30KW0@2|Bacteria,1QAV8@1224|Proteobacteria,435BG@68525|delta/epsilon subdivisions,2WZNV@28221|Deltaproteobacteria,2Z2FQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3899547_26	502025.Hoch_1913	1.474e-07	64.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.5.1.28	ko:K01448,ko:K07448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036	-	-	-	Amidase_3,Muraidase,Pkinase,SH3_3,SLH
CMS3_k127_3899547_23	525904.Tter_1099	5.383e-16	89.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3900563_3	1267535.KB906767_gene5227	6.505e-95	325.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	-	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	Na_H_Exchanger
CMS3_k127_3900563_5	1267535.KB906767_gene5226	2.4e-88	312.0	COG0475@1|root,COG0475@2|Bacteria	2|Bacteria	P	glutathione-regulated potassium exporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS3_k127_3900563_0	1242864.D187_009431	9.702e-212	683.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,438BQ@68525|delta/epsilon subdivisions,2X3M4@28221|Deltaproteobacteria,2YWGW@29|Myxococcales	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
CMS3_k127_3900563_8	448385.sce1151	5.001e-39	153.0	COG0727@1|root,COG0727@2|Bacteria,1N3UP@1224|Proteobacteria,42U10@68525|delta/epsilon subdivisions,2WQ8S@28221|Deltaproteobacteria,2Z2PB@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
CMS3_k127_3900563_1	1278073.MYSTI_00174	1.025e-111	369.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,4345V@68525|delta/epsilon subdivisions,2WYPY@28221|Deltaproteobacteria,2YUFV@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS3_k127_3900563_4	1242864.D187_003462	8.501e-90	302.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,42RGG@68525|delta/epsilon subdivisions,2X6F0@28221|Deltaproteobacteria,2YXND@29|Myxococcales	28221|Deltaproteobacteria	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_3900563_9	378806.STAUR_7502	2.146e-21	97.0	COG0607@1|root,COG0607@2|Bacteria,1PY96@1224|Proteobacteria,4356F@68525|delta/epsilon subdivisions,2WZHI@28221|Deltaproteobacteria,2Z25Y@29|Myxococcales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_3900563_6	1122247.C731_2832	5.965e-77	266.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,234VT@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_3900563_2	215803.DB30_1147	1.992e-104	361.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria,2YUFP@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_3900563_7	502025.Hoch_6620	6.223e-60	220.0	COG4213@1|root,COG4213@2|Bacteria,1MX63@1224|Proteobacteria,4306C@68525|delta/epsilon subdivisions,2WVFZ@28221|Deltaproteobacteria,2YU0U@29|Myxococcales	28221|Deltaproteobacteria	G	Periplasmic binding protein domain	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
CMS3_k127_3930325_1	502025.Hoch_4934	1.406e-18	85.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2YTTI@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_3930325_0	502025.Hoch_2730	4.008e-131	429.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,42NNZ@68525|delta/epsilon subdivisions,2WJ7C@28221|Deltaproteobacteria,2YUD7@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_3942373_4	502025.Hoch_4049	4.47e-124	407.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2YUVF@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS3_k127_3942373_10	391625.PPSIR1_16345	1.75e-77	279.0	COG0515@1|root,COG0515@2|Bacteria	391625.PPSIR1_16345|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3942373_1	401053.AciPR4_3858	9.469e-132	448.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria,2JHRQ@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3942373_5	502025.Hoch_2544	6.96e-120	389.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2YTV2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
CMS3_k127_3942373_9	867903.ThesuDRAFT_01596	1.154e-104	355.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3WCSV@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
CMS3_k127_3942373_2	502025.Hoch_2547	8.339e-129	422.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_3942373_6	502025.Hoch_2548	3.963e-115	383.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2YUZF@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS3_k127_3942373_3	502025.Hoch_2549	3.358e-126	424.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CMS3_k127_3942373_13	502025.Hoch_2551	4.086e-47	179.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,2YVHI@29|Myxococcales	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS3_k127_3942373_0	502025.Hoch_2552	1.532e-270	844.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YU6B@29|Myxococcales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_3942373_7	502025.Hoch_2553	4.232e-112	370.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2YXG3@29|Myxococcales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_3942373_8	502025.Hoch_2555	2.031e-111	382.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	MA20_34515	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS3_k127_3942373_11	1192034.CAP_7808	9.032e-65	240.0	COG1994@1|root,COG1994@2|Bacteria,1QZHR@1224|Proteobacteria,43CIT@68525|delta/epsilon subdivisions,2X7T2@28221|Deltaproteobacteria,2Z3HE@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_3942467_4	864069.MicloDRAFT_00027960	1.752e-16	85.0	COG0845@1|root,COG0845@2|Bacteria,1R3U4@1224|Proteobacteria,2TW9A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	MA20_09450	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS3_k127_3942467_2	237368.SCABRO_02472	7.61e-84	295.0	COG1131@1|root,COG1131@2|Bacteria,2J4Y7@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,DUF4162
CMS3_k127_3942467_1	323850.Shew_0425	8.442e-94	334.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2QARZ@267890|Shewanellaceae	1236|Gammaproteobacteria	V	PFAM ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_3942467_0	448385.sce0478	2.055e-96	336.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,4377E@68525|delta/epsilon subdivisions,2X289@28221|Deltaproteobacteria,2YUWN@29|Myxococcales	28221|Deltaproteobacteria	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_3942467_3	1254432.SCE1572_11160	3.824e-83	290.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_3951231_0	502025.Hoch_4879	2.25e-135	453.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_3954081_0	502025.Hoch_4143	2.019e-198	640.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_7,TPR_8
CMS3_k127_3954081_1	502025.Hoch_6088	5.171e-88	302.0	COG3172@1|root,COG3172@2|Bacteria	2|Bacteria	H	ATPase kinase involved in NAD metabolism	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CMS3_k127_3954081_5	517417.Cpar_1521	2.402e-43	163.0	COG0758@1|root,COG0758@2|Bacteria,1FE5W@1090|Chlorobi	1090|Chlorobi	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
CMS3_k127_3954081_6	502025.Hoch_6029	5.105e-19	97.0	COG0810@1|root,COG0810@2|Bacteria,1PBUV@1224|Proteobacteria,4384F@68525|delta/epsilon subdivisions,2X9X5@28221|Deltaproteobacteria,2YVPR@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	-
CMS3_k127_3954081_3	502025.Hoch_3517	3.583e-54	203.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
CMS3_k127_3954081_2	395961.Cyan7425_4481	1.693e-68	239.0	COG2454@1|root,COG2454@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
CMS3_k127_3954081_4	1278073.MYSTI_06990	6.773e-50	184.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3955187_35	378806.STAUR_2318	1.525e-39	167.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,437Y9@68525|delta/epsilon subdivisions,2X9RZ@28221|Deltaproteobacteria,2YUSF@29|Myxococcales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS3_k127_3955187_20	448385.sce4422	1.193e-69	244.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,437H5@68525|delta/epsilon subdivisions,2X2QG@28221|Deltaproteobacteria,2YUX3@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS3_k127_3955187_8	502025.Hoch_6081	1.838e-115	382.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2YUM7@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3955187_5	1123368.AUIS01000031_gene1422	3.487e-136	441.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_3955187_9	502025.Hoch_0262	1.754e-105	360.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_3955187_0	1192034.CAP_0074	1.935e-226	723.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_3955187_28	1192034.CAP_0075	4.09e-53	193.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z13I@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_3955187_27	926566.Terro_0848	8.181e-54	199.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_3955187_46	1157640.AQWO01000018_gene5438	4.512e-05	57.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
CMS3_k127_3955187_43	391625.PPSIR1_00907	4.544e-19	104.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3955187_4	215803.DB30_1345	1.18e-163	525.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria,437FH@68525|delta/epsilon subdivisions,2X2N4@28221|Deltaproteobacteria,2YTXN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
CMS3_k127_3955187_29	502025.Hoch_4230	1.016e-52	196.0	COG0524@1|root,COG0524@2|Bacteria,1PEFW@1224|Proteobacteria,42T1E@68525|delta/epsilon subdivisions,2WP6U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PfkB domain protein	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_3955187_40	1094980.Mpsy_1538	9.402e-21	106.0	COG2304@1|root,COG4934@1|root,arCOG02902@2157|Archaea,arCOG03665@2157|Archaea	2157|Archaea	O	tripeptidyl-peptidase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,Peptidase_S8,Pro-kuma_activ,VWA,VWA_2
CMS3_k127_3955187_49	66373.JOFQ01000004_gene5335	0.0007567	47.0	COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS3_k127_3955187_41	1304878.AUGD01000011_gene4929	2.584e-20	98.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria,3JUZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3955187_48	1035191.HMPREF0185_03240	0.00069	52.0	COG3712@1|root,COG3712@2|Bacteria,1RGU3@1224|Proteobacteria,2VFK9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	PT	Domain of unknown function (DUF4974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4880,DUF4974,FecR
CMS3_k127_3955187_1	502025.Hoch_5477	2.793e-216	687.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YWI7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
CMS3_k127_3955187_47	446469.Sked_35370	0.0001837	55.0	COG2909@1|root,COG2909@2|Bacteria,2I6D5@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS3_k127_3955187_19	330214.NIDE4382	2.353e-70	271.0	COG0400@1|root,COG0400@2|Bacteria,3J1DU@40117|Nitrospirae	40117|Nitrospirae	S	Alpha/beta hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS3_k127_3955187_22	502025.Hoch_0418	1.011e-64	246.0	COG4783@1|root,COG4783@2|Bacteria,1PXKA@1224|Proteobacteria,43DVG@68525|delta/epsilon subdivisions,2X8Y4@28221|Deltaproteobacteria,2Z0G0@29|Myxococcales	28221|Deltaproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3955187_26	130081.XP_005706730.1	6.292e-57	209.0	COG1132@1|root,KOG0058@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.6.3.44	ko:K02069,ko:K05657,ko:K05658	ko02010,ko04976,ko05206,ko05226,map02010,map04976,map05206,map05226	M00211	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko04090,ko04147	3.A.1.201,9.B.25.1	-	-	ABC_membrane,ABC_tran
CMS3_k127_3955187_15	130081.XP_005706730.1	1.055e-81	290.0	COG1132@1|root,KOG0058@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.6.3.44	ko:K02069,ko:K05657,ko:K05658	ko02010,ko04976,ko05206,ko05226,map02010,map04976,map05206,map05226	M00211	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko04090,ko04147	3.A.1.201,9.B.25.1	-	-	ABC_membrane,ABC_tran
CMS3_k127_3955187_12	502025.Hoch_4659	2.532e-90	312.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YYKC@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_3955187_6	309807.SRU_1574	2.232e-133	432.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1FJJ9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_3955187_30	502025.Hoch_5724	2.118e-49	180.0	COG1610@1|root,COG1610@2|Bacteria,1PS1I@1224|Proteobacteria,43A7B@68525|delta/epsilon subdivisions,2X2EM@28221|Deltaproteobacteria,2Z2BW@29|Myxococcales	28221|Deltaproteobacteria	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS3_k127_3955187_38	1144275.COCOR_06347	2.712e-27	119.0	COG0631@1|root,COG0631@2|Bacteria,1P056@1224|Proteobacteria	1224|Proteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_3955187_16	1144275.COCOR_01712	1.092e-78	288.0	2EHQ8@1|root,33BG0@2|Bacteria	2|Bacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS3_k127_3955187_2	502025.Hoch_0175	1.487e-209	693.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria,2YXDW@29|Myxococcales	28221|Deltaproteobacteria	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS3_k127_3955187_36	1254432.SCE1572_32105	6.208e-31	129.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WRIB@28221|Deltaproteobacteria,2YVSI@29|Myxococcales	28221|Deltaproteobacteria	S	CBS domain	-	-	-	ko:K04767,ko:K07168,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_3955187_39	502025.Hoch_1899	1.852e-25	115.0	COG2524@1|root,COG2524@2|Bacteria,1QANB@1224|Proteobacteria,43E2I@68525|delta/epsilon subdivisions,2WZHW@28221|Deltaproteobacteria,2Z26K@29|Myxococcales	28221|Deltaproteobacteria	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_3955187_44	1254432.SCE1572_33375	1.402e-17	93.0	2BIBC@1|root,32CH4@2|Bacteria,1PDD7@1224|Proteobacteria,435G3@68525|delta/epsilon subdivisions,2WZTJ@28221|Deltaproteobacteria,2Z2QE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3955187_25	502025.Hoch_6657	4.955e-57	211.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3955187_31	502025.Hoch_3172	2.37e-48	194.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3955187_18	502025.Hoch_6657	2.595e-72	255.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3955187_7	1254432.SCE1572_35730	5.596e-123	412.0	COG3852@1|root,COG3852@2|Bacteria,1R0D4@1224|Proteobacteria,43CVR@68525|delta/epsilon subdivisions,2X83R@28221|Deltaproteobacteria,2Z3K9@29|Myxococcales	28221|Deltaproteobacteria	F	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Protoglobin
CMS3_k127_3955187_3	1192034.CAP_9006	2.019e-172	553.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_3955187_37	1173024.KI912151_gene2421	2.657e-28	119.0	COG1544@1|root,COG1544@2|Bacteria,1GR8R@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Sigma 54 modulation protein S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
CMS3_k127_3955187_33	502025.Hoch_0288	1.629e-41	168.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3955187_10	502025.Hoch_2046	2.54e-99	337.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2Z35Q@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS3_k127_3955187_32	1192034.CAP_3357	5.599e-48	184.0	COG0515@1|root,COG0515@2|Bacteria,1Q38J@1224|Proteobacteria,438ZJ@68525|delta/epsilon subdivisions,2X44T@28221|Deltaproteobacteria,2YY98@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	masK	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_3955187_17	43989.cce_3914	1.452e-75	280.0	COG4221@1|root,COG4221@2|Bacteria,1G4EK@1117|Cyanobacteria,3KIA0@43988|Cyanothece	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3955187_34	1278073.MYSTI_07641	3.466e-41	173.0	COG4447@1|root,COG4447@2|Bacteria,1QX8J@1224|Proteobacteria,43C1P@68525|delta/epsilon subdivisions,2X7CA@28221|Deltaproteobacteria,2YW1N@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS3_k127_3955187_42	448385.sce6202	1.406e-19	103.0	COG0526@1|root,COG0526@2|Bacteria,1QT4H@1224|Proteobacteria,4356V@68525|delta/epsilon subdivisions,2X96A@28221|Deltaproteobacteria,2Z26T@29|Myxococcales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_8
CMS3_k127_3955187_23	404589.Anae109_2837	1.613e-62	222.0	COG2885@1|root,COG2885@2|Bacteria,1Q9RC@1224|Proteobacteria,434J9@68525|delta/epsilon subdivisions,2WYWG@28221|Deltaproteobacteria,2Z0SZ@29|Myxococcales	28221|Deltaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3955187_11	404589.Anae109_2836	3.165e-93	326.0	COG1651@1|root,COG1651@2|Bacteria,1Q3GQ@1224|Proteobacteria,43994@68525|delta/epsilon subdivisions,2X4GG@28221|Deltaproteobacteria,2YYZ6@29|Myxococcales	28221|Deltaproteobacteria	O	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
CMS3_k127_3955187_45	335543.Sfum_2508	1.319e-14	86.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3955187_13	518766.Rmar_2536	4.162e-87	293.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1FIVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3955187_21	87626.PTD2_11099	1.279e-65	240.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S1AK@1236|Gammaproteobacteria,2Q4EP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	VPA0558	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_3955187_14	87626.PTD2_11104	1.865e-85	309.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1S8DW@1236|Gammaproteobacteria,2Q4B8@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_3955187_24	87626.PTD2_11109	3.316e-58	210.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,1SF26@1236|Gammaproteobacteria,2Q452@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_3956381_1	1278073.MYSTI_01470	2.322e-47	180.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria	1224|Proteobacteria	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS3_k127_3956381_5	641524.ADICYQ_3642	2.534e-23	111.0	COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,47PD9@768503|Cytophagia	976|Bacteroidetes	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD,PKD
CMS3_k127_3956381_4	1047013.AQSP01000131_gene1844	6.148e-24	111.0	COG1238@1|root,COG1238@2|Bacteria	2|Bacteria	I	metal cluster binding	yqaA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	SNARE_assoc
CMS3_k127_3956381_2	416348.Hlac_2869	4.254e-45	188.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
CMS3_k127_3956381_0	324602.Caur_1827	1.795e-61	217.0	COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi,37502@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS3_k127_3961257_1	215803.DB30_4129	6.19e-90	323.0	COG1409@1|root,COG1409@2|Bacteria,1Q1ST@1224|Proteobacteria,437FZ@68525|delta/epsilon subdivisions,2X2NK@28221|Deltaproteobacteria,2YU0N@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_3961257_2	1192034.CAP_2808	5.524e-57	216.0	COG4676@1|root,COG4676@2|Bacteria,1Q2DI@1224|Proteobacteria,437ZR@68525|delta/epsilon subdivisions,2X39P@28221|Deltaproteobacteria,2YV0B@29|Myxococcales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3961257_5	701347.Entcl_0960	0.000355	46.0	COG1476@1|root,COG1476@2|Bacteria,1QUCQ@1224|Proteobacteria,1T1TH@1236|Gammaproteobacteria,3X2I3@547|Enterobacter	1236|Gammaproteobacteria	K	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM,HTH_3
CMS3_k127_3961257_0	502025.Hoch_5053	1.365e-93	314.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
CMS3_k127_3966142_3	502025.Hoch_0363	1.274e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,1PXHP@1224|Proteobacteria,434K6@68525|delta/epsilon subdivisions,2WYXE@28221|Deltaproteobacteria,2Z0V1@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16
CMS3_k127_3966142_2	1196835.A458_20090	8.385e-31	134.0	COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1RSIE@1236|Gammaproteobacteria,1Z0V8@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
CMS3_k127_3966142_1	502025.Hoch_6795	9.05e-52	202.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_3966142_0	1297742.A176_03889	2.747e-56	198.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2YY0V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS3_k127_3974722_5	1297742.A176_04476	2.257e-119	417.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_3974722_6	626523.GCWU000342_01662	5.973e-111	374.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
CMS3_k127_3974722_8	1144275.COCOR_07096	4.706e-83	288.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2YUTZ@29|Myxococcales	28221|Deltaproteobacteria	M	Mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS3_k127_3974722_2	502025.Hoch_5049	6.975e-150	506.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2YUC2@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_3974722_13	404589.Anae109_0167	1.943e-54	217.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42S50@68525|delta/epsilon subdivisions,2X5NZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_3974722_0	502025.Hoch_0424	7.244e-196	647.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YU6B@29|Myxococcales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_3974722_12	502025.Hoch_0425	9.348e-71	263.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS3_k127_3974722_22	7918.ENSLOCP00000002858	4.771e-11	70.0	COG0484@1|root,KOG0715@2759|Eukaryota,38H0N@33154|Opisthokonta,3BAQ9@33208|Metazoa,3CZDG@33213|Bilateria,481CD@7711|Chordata,48V52@7742|Vertebrata,49VVV@7898|Actinopterygii	33208|Metazoa	O	homolog subfamily A member	DNAJA3	GO:0000002,GO:0000122,GO:0001775,GO:0001776,GO:0001932,GO:0001933,GO:0001941,GO:0001959,GO:0001960,GO:0002119,GO:0002164,GO:0002260,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0005102,GO:0005113,GO:0005126,GO:0005133,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006355,GO:0006357,GO:0006457,GO:0006469,GO:0006725,GO:0006807,GO:0006915,GO:0006919,GO:0006924,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007264,GO:0007275,GO:0007528,GO:0007568,GO:0007569,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008285,GO:0009058,GO:0009059,GO:0009295,GO:0009790,GO:0009791,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010556,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010951,GO:0010952,GO:0012501,GO:0016020,GO:0016043,GO:0019219,GO:0019220,GO:0019222,GO:0019897,GO:0019898,GO:0019899,GO:0019900,GO:0019901,GO:0022407,GO:0022409,GO:0023051,GO:0023052,GO:0023057,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030162,GO:0030217,GO:0030234,GO:0030544,GO:0030695,GO:0030971,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031347,GO:0031348,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031594,GO:0031647,GO:0031974,GO:0032042,GO:0032088,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032944,GO:0032946,GO:0033036,GO:0033077,GO:0033673,GO:0034097,GO:0034341,GO:0034613,GO:0034641,GO:0034645,GO:0035556,GO:0042102,GO:0042110,GO:0042127,GO:0042129,GO:0042221,GO:0042325,GO:0042326,GO:0042592,GO:0042645,GO:0042981,GO:0043029,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043113,GO:0043122,GO:0043124,GO:0043154,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043280,GO:0043281,GO:0043433,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045087,GO:0045088,GO:0045202,GO:0045211,GO:0045321,GO:0045785,GO:0045824,GO:0045859,GO:0045861,GO:0045862,GO:0045892,GO:0045934,GO:0045936,GO:0046483,GO:0046649,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050670,GO:0050671,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050821,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051059,GO:0051082,GO:0051090,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051252,GO:0051253,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051641,GO:0051668,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060330,GO:0060331,GO:0060334,GO:0060336,GO:0060548,GO:0060589,GO:0060759,GO:0060761,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070227,GO:0070231,GO:0070663,GO:0070665,GO:0070727,GO:0071340,GO:0071704,GO:0071840,GO:0071887,GO:0071944,GO:0072657,GO:0080090,GO:0080134,GO:0090304,GO:0097060,GO:0098590,GO:0098772,GO:0098794,GO:0099173,GO:1901360,GO:1901576,GO:1902531,GO:1902532,GO:1902679,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903507,GO:1990782,GO:2000112,GO:2000113,GO:2000116,GO:2000117,GO:2001056,GO:2001141	-	ko:K09504	ko05203,map05203	-	-	-	ko00000,ko00001,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_3974722_3	1242864.D187_005763	2.482e-134	447.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_3974722_20	1449353.JQMQ01000005_gene4783	6.548e-17	95.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,2NFGQ@228398|Streptacidiphilus	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_3974722_23	391625.PPSIR1_09216	7.425e-10	68.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_3974722_7	502025.Hoch_0427	1.073e-86	309.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,2YVME@29|Myxococcales	28221|Deltaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS3_k127_3974722_17	502025.Hoch_0428	5.876e-46	177.0	2AGTU@1|root,31723@2|Bacteria,1PYAB@1224|Proteobacteria,4357A@68525|delta/epsilon subdivisions,2WZI9@28221|Deltaproteobacteria,2Z27H@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3974722_4	502025.Hoch_0430	2.904e-128	423.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2YTY2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
CMS3_k127_3974722_1	502025.Hoch_0431	1.953e-171	548.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,2YU1V@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_3974722_19	502025.Hoch_0432	3.029e-40	154.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2YVQW@29|Myxococcales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS3_k127_3974722_18	502025.Hoch_0119	2.788e-43	169.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,2YVUV@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CMS3_k127_3974722_11	502025.Hoch_1776	1.018e-73	256.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2YVCY@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS3_k127_3974722_16	502025.Hoch_6841	9.608e-53	191.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2WP5B@28221|Deltaproteobacteria,2YVUD@29|Myxococcales	28221|Deltaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS3_k127_3974722_9	246197.MXAN_5598	6.593e-78	298.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,TSP_3
CMS3_k127_3974722_10	1197130.BAFM01000012_gene2204	1.304e-75	290.0	arCOG02903@1|root,arCOG03612@1|root,arCOG02903@2157|Archaea,arCOG03612@2157|Archaea	2157|Archaea	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Big_1,DUF1573,PKD,VWA
CMS3_k127_3976145_7	644282.Deba_0503	1.347e-34	140.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2WK3K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	(EAL) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
CMS3_k127_3976145_2	502025.Hoch_6344	2.727e-186	586.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2YXJE@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_3976145_1	502025.Hoch_0164	5.487e-320	1005.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,1Q385@1224|Proteobacteria,433YW@68525|delta/epsilon subdivisions,2X44A@28221|Deltaproteobacteria,2YY7W@29|Myxococcales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_3976145_3	1254432.SCE1572_12230	2.334e-100	351.0	COG1073@1|root,COG1073@2|Bacteria,1QRTY@1224|Proteobacteria,433U7@68525|delta/epsilon subdivisions,2X3GS@28221|Deltaproteobacteria,2YW15@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3976145_6	1242864.D187_003054	1.834e-52	197.0	COG0515@1|root,COG0515@2|Bacteria	1242864.D187_003054|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3976145_8	1225785.CM001983_gene2571	4.959e-21	102.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,1RP35@1236|Gammaproteobacteria,2JDUX@204037|Dickeya	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
CMS3_k127_3976145_0	502025.Hoch_0023	3.996e-320	1058.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria	1224|Proteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS3_k127_3976145_5	502025.Hoch_0022	8.334e-66	232.0	COG2804@1|root,COG2804@2|Bacteria,1Q2HQ@1224|Proteobacteria,4384J@68525|delta/epsilon subdivisions,2X3EH@28221|Deltaproteobacteria,2YVQB@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE_N
CMS3_k127_3981294_9	502025.Hoch_2608	9.524e-35	138.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_3981294_14	1192034.CAP_5114	2.025e-09	70.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
CMS3_k127_3981294_2	1242864.D187_003116	1.085e-130	431.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,42SJE@68525|delta/epsilon subdivisions,2WPS5@28221|Deltaproteobacteria,2YWQM@29|Myxococcales	28221|Deltaproteobacteria	C	Retinal pigment epithelial membrane protein	-	-	1.13.11.75	ko:K00464	-	-	R09601	RC00912	ko00000,ko01000	-	-	-	RPE65,TAT_signal
CMS3_k127_3981294_10	1242864.D187_003117	1.793e-32	145.0	COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,42VQ5@68525|delta/epsilon subdivisions,2WSX2@28221|Deltaproteobacteria,2YZU5@29|Myxococcales	28221|Deltaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_3981294_16	555793.WSK_2500	2.168e-07	62.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,2K0VB@204457|Sphingomonadales	204457|Sphingomonadales	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
CMS3_k127_3981294_3	1278073.MYSTI_00814	5.258e-115	383.0	COG1520@1|root,COG2234@1|root,COG1520@2|Bacteria,COG2234@2|Bacteria,1NI1E@1224|Proteobacteria,430IZ@68525|delta/epsilon subdivisions,2WW3C@28221|Deltaproteobacteria,2YYH1@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M10
CMS3_k127_3981294_6	502025.Hoch_5411	6.564e-84	286.0	COG0647@1|root,COG0647@2|Bacteria	2|Bacteria	G	UMP catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_3981294_1	448385.sce3269	9.201e-154	499.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2WINT@28221|Deltaproteobacteria,2YUPM@29|Myxococcales	28221|Deltaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS3_k127_3981294_7	88036.EFJ36013	1.549e-73	258.0	COG0580@1|root,KOG0223@2759|Eukaryota,37I8V@33090|Viridiplantae,3GEXA@35493|Streptophyta	35493|Streptophyta	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006833,GO:0008150,GO:0015250,GO:0015267,GO:0015318,GO:0015840,GO:0016020,GO:0016021,GO:0019755,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042044,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944	-	ko:K09874	-	-	-	-	ko00000,ko02000	1.A.8.12	-	-	MIP
CMS3_k127_3981294_4	1183438.GKIL_2889	1.731e-111	387.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_3981294_17	498211.CJA_0974	4.154e-06	56.0	COG0705@1|root,COG0705@2|Bacteria,1N8NS@1224|Proteobacteria,1SD4M@1236|Gammaproteobacteria,1FHFK@10|Cellvibrio	1236|Gammaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_3981294_5	502025.Hoch_5811	8.723e-96	341.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3981294_15	1254432.SCE1572_09955	2.747e-08	58.0	28HI5@1|root,2Z7TP@2|Bacteria,1Q2A9@1224|Proteobacteria,437X1@68525|delta/epsilon subdivisions,2X36R@28221|Deltaproteobacteria,2YUJV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3981294_0	502025.Hoch_3205	7.555e-181	579.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,4320V@68525|delta/epsilon subdivisions,2WW8U@28221|Deltaproteobacteria,2YW2I@29|Myxococcales	28221|Deltaproteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C
CMS3_k127_3981294_13	502025.Hoch_3204	1.849e-15	81.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,2YTST@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_3981294_11	671143.DAMO_1292	1.363e-29	119.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_3982337_1	1297742.A176_04083	7.622e-115	376.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,42PZ0@68525|delta/epsilon subdivisions,2WM9Y@28221|Deltaproteobacteria,2YUF3@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_3982337_0	1415754.JQMK01000002_gene2036	2.973e-147	494.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RPG7@1236|Gammaproteobacteria,466C3@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3982337_3	448385.sce8826	8.715e-12	74.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,F5_F8_type_C,PA14,Phosphoesterase
CMS3_k127_3987189_0	502025.Hoch_3749	1.263e-104	342.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_3991529_1	502025.Hoch_1928	1.699e-85	293.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CMS3_k127_3991529_0	502025.Hoch_1929	1.074e-151	485.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YTXZ@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS3_k127_4007108_2	502025.Hoch_5901	3.887e-47	175.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,432MH@68525|delta/epsilon subdivisions,2WYFU@28221|Deltaproteobacteria,2YVDK@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_4007108_0	644107.SL1157_1128	5.355e-144	477.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,4NAJC@97050|Ruegeria	28211|Alphaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_4007108_3	502025.Hoch_5900	8.024e-36	150.0	COG0457@1|root,COG2214@1|root,COG0457@2|Bacteria,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS3_k127_4007108_1	502025.Hoch_2574	2.425e-54	209.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2Z01G@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
CMS3_k127_4012602_0	502025.Hoch_2431	1.501e-131	424.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS3_k127_4012602_1	502025.Hoch_2430	4.71e-117	382.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,2YUVT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS3_k127_4012602_3	502025.Hoch_6592	5.109e-59	213.0	2AI7D@1|root,318MR@2|Bacteria,1Q0MU@1224|Proteobacteria,436RD@68525|delta/epsilon subdivisions,2X1E8@28221|Deltaproteobacteria,2YW7E@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4012602_4	502025.Hoch_6591	7.799e-46	171.0	2E05E@1|root,32VTR@2|Bacteria,1N5CW@1224|Proteobacteria,431HU@68525|delta/epsilon subdivisions,2WWRZ@28221|Deltaproteobacteria,2YVXX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4012602_5	502025.Hoch_6590	1.033e-42	158.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_4012602_2	502025.Hoch_6589	8.247e-67	228.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_4021726_2	502025.Hoch_0133	1.158e-165	527.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS3_k127_4021726_3	502025.Hoch_0132	5.447e-92	311.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WQJT@28221|Deltaproteobacteria,2YV3J@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx GppA	gppA-1	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS3_k127_4021726_6	498848.TaqDRAFT_5308	1.558e-06	55.0	COG0745@1|root,COG0745@2|Bacteria,1WK4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_4021726_0	502025.Hoch_5161	0.0	1012.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
CMS3_k127_4021726_5	502025.Hoch_1913	2.063e-07	63.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.5.1.28	ko:K01448,ko:K07448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036	-	-	-	Amidase_3,Muraidase,Pkinase,SH3_3,SLH
CMS3_k127_4021726_1	404589.Anae109_3049	2.191e-189	626.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
CMS3_k127_4023176_18	1173020.Cha6605_2511	1.464e-13	77.0	COG1309@1|root,COG1309@2|Bacteria,1GCMJ@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4023176_2	502025.Hoch_2178	4.071e-166	538.0	COG1807@1|root,COG1807@2|Bacteria,1QX93@1224|Proteobacteria,43C25@68525|delta/epsilon subdivisions,2X7CQ@28221|Deltaproteobacteria,2YUUE@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4023176_10	502025.Hoch_2177	5.263e-91	311.0	2A4RR@1|root,30TD5@2|Bacteria,1PD62@1224|Proteobacteria,435EI@68525|delta/epsilon subdivisions,2WZS8@28221|Deltaproteobacteria,2Z2MR@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4023176_3	502025.Hoch_2176	4.627e-161	524.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4023176_13	502025.Hoch_6070	4.085e-45	186.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_6070|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4023176_23	679926.Mpet_0132	4.959e-06	60.0	arCOG03264@1|root,arCOG06661@1|root,arCOG03264@2157|Archaea,arCOG06661@2157|Archaea	2157|Archaea	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Glucodextran_C,PEGA
CMS3_k127_4023176_17	65497.JODV01000002_gene4308	1.371e-18	99.0	COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,2GNTM@201174|Actinobacteria,4E143@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Metallophos,NAGPA
CMS3_k127_4023176_5	502025.Hoch_3669	5.896e-118	394.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4023176_21	1242864.D187_004623	1.176e-09	72.0	COG0457@1|root,COG0457@2|Bacteria,1PCAS@1224|Proteobacteria,433V6@68525|delta/epsilon subdivisions,2X3MF@28221|Deltaproteobacteria,2YWHN@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4023176_20	1183438.GKIL_3066	2.415e-10	73.0	COG2706@1|root,COG2706@2|Bacteria,1GQSX@1117|Cyanobacteria	1117|Cyanobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TIG,VCBS
CMS3_k127_4023176_11	67281.JNZZ01000001_gene2185	1.286e-68	255.0	COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,2GJ9M@201174|Actinobacteria,4194K@629295|Streptomyces griseus group	201174|Actinobacteria	MV	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1,SLT
CMS3_k127_4023176_6	502025.Hoch_2172	1.741e-116	398.0	COG0515@1|root,COG3266@1|root,COG0515@2|Bacteria,COG3266@2|Bacteria,1PEIZ@1224|Proteobacteria,433VS@68525|delta/epsilon subdivisions,2X3Q2@28221|Deltaproteobacteria,2YWTJ@29|Myxococcales	2|Bacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1,3.4.16.4	ko:K01286,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1565,Peptidase_S11,Pkinase,SPOR
CMS3_k127_4023176_7	83406.HDN1F_19500	7.529e-115	378.0	COG1633@1|root,COG1633@2|Bacteria,1R8DF@1224|Proteobacteria,1RSPX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4023176_9	1192034.CAP_5127	9.817e-95	331.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,4341P@68525|delta/epsilon subdivisions,2X4PD@28221|Deltaproteobacteria,2YZCK@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
CMS3_k127_4023176_12	469383.Cwoe_1575	2.344e-54	201.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4CPUH@84995|Rubrobacteria	84995|Rubrobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_4023176_4	502025.Hoch_2252	5.172e-161	512.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2YX5K@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
CMS3_k127_4023176_14	290397.Adeh_1639	6.126e-30	136.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2Z33F@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_4023176_1	502025.Hoch_2251	4.275e-177	564.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,2YU5H@29|Myxococcales	28221|Deltaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS3_k127_4023176_0	502025.Hoch_2249	6.973e-201	633.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2YWXC@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS3_k127_4023176_8	448385.sce4069	8.718e-114	389.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6Z3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat
CMS3_k127_4030746_17	1192034.CAP_4000	1.885e-08	66.0	COG2067@1|root,COG2067@2|Bacteria,1Q2WT@1224|Proteobacteria,438JN@68525|delta/epsilon subdivisions,2X3UB@28221|Deltaproteobacteria,2YX4H@29|Myxococcales	28221|Deltaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_4030746_7	1347368.HG964407_gene6685	8.797e-94	325.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,1ZCAI@1386|Bacillus	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS3_k127_4030746_9	56780.SYN_02346	5.719e-88	299.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_4030746_8	1242864.D187_006933	3.354e-89	308.0	COG3291@1|root,COG3291@2|Bacteria,1Q2FH@1224|Proteobacteria,4381E@68525|delta/epsilon subdivisions,2X3BG@28221|Deltaproteobacteria,2YV9C@29|Myxococcales	28221|Deltaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS3_k127_4030746_6	215803.DB30_3062	5.331e-99	331.0	2935G@1|root,2ZQNI@2|Bacteria,1Q1RV@1224|Proteobacteria,437F3@68525|delta/epsilon subdivisions,2X2MJ@28221|Deltaproteobacteria,2YTTE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4030746_5	1380390.JIAT01000011_gene2696	1.159e-109	377.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CS0R@84995|Rubrobacteria	84995|Rubrobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS3_k127_4030746_4	1254432.SCE1572_02795	1.35e-110	375.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4030746_12	448385.sce1077	4.513e-40	164.0	COG3206@1|root,COG3206@2|Bacteria,1QZTF@1224|Proteobacteria,43CNF@68525|delta/epsilon subdivisions,2X7VS@28221|Deltaproteobacteria,2Z3IM@29|Myxococcales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS3_k127_4030746_16	215803.DB30_5989	6.806e-13	83.0	COG3391@1|root,COG3391@2|Bacteria,1Q2JN@1224|Proteobacteria,4386H@68525|delta/epsilon subdivisions,2X9ZH@28221|Deltaproteobacteria,2YVZH@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Stig1
CMS3_k127_4030746_1	448385.sce8739	3.104e-170	553.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,4380T@68525|delta/epsilon subdivisions,2X3AT@28221|Deltaproteobacteria,2YZH7@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4030746_0	215803.DB30_0568	1.09e-181	610.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase,Pkinase_Tyr,WD40
CMS3_k127_4030746_10	1192034.CAP_1501	4.543e-66	242.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2WNI2@28221|Deltaproteobacteria,2YV54@29|Myxococcales	28221|Deltaproteobacteria	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_4030746_2	1192034.CAP_1502	5.771e-134	440.0	2AGSA@1|root,31707@2|Bacteria,1PY8B@1224|Proteobacteria,4355T@68525|delta/epsilon subdivisions,2WZGR@28221|Deltaproteobacteria,2Z247@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4030746_11	1192034.CAP_1503	1.121e-49	187.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,434YV@68525|delta/epsilon subdivisions,2WZ9S@28221|Deltaproteobacteria,2Z1NI@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4030746_14	1279009.ADICEAN_03167	4.852e-29	119.0	COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,47S1E@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF3127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3127
CMS3_k127_4030746_3	1394178.AWOO02000081_gene2194	1.891e-119	392.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4EG6Y@85012|Streptosporangiales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_4033602_0	378806.STAUR_2312	1.156e-134	438.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2YY0V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS3_k127_4033602_4	1254432.SCE1572_51580	7.625e-36	139.0	COG0517@1|root,COG0517@2|Bacteria,1N68U@1224|Proteobacteria,42UEN@68525|delta/epsilon subdivisions,2X9VF@28221|Deltaproteobacteria,2YVE6@29|Myxococcales	28221|Deltaproteobacteria	K	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_4033602_7	502025.Hoch_5681	1.152e-12	82.0	COG2010@1|root,COG2010@2|Bacteria,1PI4D@1224|Proteobacteria,435HI@68525|delta/epsilon subdivisions,2WZV4@28221|Deltaproteobacteria,2Z2TI@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4033602_2	502025.Hoch_5680	1.141e-78	300.0	29EP2@1|root,301KY@2|Bacteria,1Q96E@1224|Proteobacteria,437IB@68525|delta/epsilon subdivisions,2X2RW@28221|Deltaproteobacteria,2Z2TH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4033602_6	861299.J421_0153	8.062e-18	99.0	COG4409@1|root,COG4409@2|Bacteria,1ZUI0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4033602_3	1165841.SULAR_03857	4.377e-48	180.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4033602_1	502025.Hoch_0724	2.25e-132	451.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,42NRH@68525|delta/epsilon subdivisions,2WNIB@28221|Deltaproteobacteria,2Z01C@29|Myxococcales	28221|Deltaproteobacteria	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
CMS3_k127_4052783_0	502025.Hoch_5309	1.651e-277	862.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS3_k127_4052783_2	502025.Hoch_5307	2.863e-116	378.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,42T9X@68525|delta/epsilon subdivisions,2WP59@28221|Deltaproteobacteria,2YWRF@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_4052783_1	502025.Hoch_5306	2.686e-147	501.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2YVEB@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
CMS3_k127_4052783_3	1267005.KB911256_gene1500	2.505e-11	76.0	2DC2D@1|root,2ZCMG@2|Bacteria,1R8RP@1224|Proteobacteria,2U2PD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3829)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3829
CMS3_k127_4072039_4	870187.Thini_2547	2.159e-13	83.0	COG4188@1|root,COG4188@2|Bacteria,1QUVG@1224|Proteobacteria,1T22C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N,PAF-AH_p_II
CMS3_k127_4072039_3	1297742.A176_00720	1.165e-32	141.0	2CDI5@1|root,2Z7ZQ@2|Bacteria,1Q9TA@1224|Proteobacteria,42QB0@68525|delta/epsilon subdivisions,2WMJT@28221|Deltaproteobacteria,2Z1T9@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4072039_0	502025.Hoch_3299	8.748e-152	487.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WJ8G@28221|Deltaproteobacteria,2Z31K@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS3_k127_4072039_2	502025.Hoch_3298	2.192e-46	170.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2Z1I1@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_4072039_1	502025.Hoch_3297	2.044e-53	205.0	COG0810@1|root,COG0810@2|Bacteria,1NG3C@1224|Proteobacteria,42V3M@68525|delta/epsilon subdivisions,2WS05@28221|Deltaproteobacteria,2YZ7E@29|Myxococcales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
CMS3_k127_4074477_3	886293.Sinac_1156	3.696e-222	727.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4074477_1	886293.Sinac_1156	2.094e-240	790.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4074477_13	378806.STAUR_0867	6.722e-76	284.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria,2YU27@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS3_k127_4074477_14	502025.Hoch_5670	1.056e-62	228.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,433WA@68525|delta/epsilon subdivisions,2X3U0@28221|Deltaproteobacteria,2YX3S@29|Myxococcales	28221|Deltaproteobacteria	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_4074477_0	502025.Hoch_5669	2.16e-265	835.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YYWB@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS3_k127_4074477_8	391625.PPSIR1_30973	1.373e-125	419.0	COG0840@1|root,COG0840@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CMS3_k127_4074477_17	502025.Hoch_0076	4.41e-20	94.0	COG1826@1|root,COG1826@2|Bacteria,1PJQP@1224|Proteobacteria,4358S@68525|delta/epsilon subdivisions,2WZJX@28221|Deltaproteobacteria,2Z2A9@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_4074477_11	502025.Hoch_0075	9.443e-86	294.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2YVGX@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS3_k127_4074477_5	502025.Hoch_0074	1.559e-144	482.0	COG0457@1|root,COG0515@1|root,COG3170@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3170@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,PP2C_2,Pkinase,TPR_12
CMS3_k127_4074477_15	502025.Hoch_0073	3.997e-51	190.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
CMS3_k127_4074477_2	671143.DAMO_1619	7.033e-235	741.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_4074477_6	671143.DAMO_1620	3.782e-138	473.0	COG1013@1|root,COG1013@2|Bacteria,2NPAM@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_4074477_12	211114.JOEF01000017_gene3833	1.144e-85	292.0	COG0491@1|root,COG0491@2|Bacteria,2GN7R@201174|Actinobacteria,4E1FN@85010|Pseudonocardiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4074477_4	886293.Sinac_1421	2.196e-168	551.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4074477_16	1415780.JPOG01000001_gene2342	1.294e-34	141.0	COG1309@1|root,COG1309@2|Bacteria,1N6FM@1224|Proteobacteria,1SZ1U@1236|Gammaproteobacteria,1XCWH@135614|Xanthomonadales	135614|Xanthomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4074477_9	448385.sce7609	2.042e-124	416.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2YXGF@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_4074477_7	671143.DAMO_2705	1.424e-136	465.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS3_k127_4074477_10	1254432.SCE1572_44000	3.826e-100	340.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CMS3_k127_4092684_22	515635.Dtur_1285	5.926e-08	65.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
CMS3_k127_4092684_3	502025.Hoch_6000	8.322e-163	548.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJRH@28221|Deltaproteobacteria,2YUPB@29|Myxococcales	28221|Deltaproteobacteria	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_4092684_4	1123258.AQXZ01000018_gene668	3.251e-135	457.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_4092684_15	502025.Hoch_5999	2.732e-47	182.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_5999|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4092684_16	471855.Shel_27050	1.514e-41	177.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CUGE@84998|Coriobacteriia	84998|Coriobacteriia	T	phosphatase 2C	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
CMS3_k127_4092684_12	1297742.A176_06873	1.501e-67	254.0	COG0546@1|root,COG0546@2|Bacteria,1P19B@1224|Proteobacteria,431NT@68525|delta/epsilon subdivisions,2WWU8@28221|Deltaproteobacteria,2YVRG@29|Myxococcales	28221|Deltaproteobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4092684_21	309799.DICTH_0124	2.94e-08	63.0	2E1HF@1|root,32WVJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3996
CMS3_k127_4092684_10	502025.Hoch_5306	7.03e-87	313.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2YVEB@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
CMS3_k127_4092684_11	935261.JAGL01000032_gene3808	6.184e-75	269.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,43JDB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_4092684_17	204669.Acid345_1922	2.1e-41	157.0	COG2259@1|root,COG2259@2|Bacteria,3Y4XF@57723|Acidobacteria,2JMZV@204432|Acidobacteriia	204432|Acidobacteriia	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS3_k127_4092684_19	5786.XP_003288870.1	1.017e-24	114.0	29AKT@1|root,2RHPG@2759|Eukaryota,3XHBQ@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4092684_7	639283.Snov_2500	4.268e-114	379.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,3F0C1@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
CMS3_k127_4092684_20	221027.JO40_08920	2.154e-10	70.0	COG0454@1|root,COG0456@2|Bacteria,2J8DV@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_4092684_0	502025.Hoch_0152	0.0	1192.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,42NF1@68525|delta/epsilon subdivisions,2WK52@28221|Deltaproteobacteria,2YUP8@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
CMS3_k127_4092684_1	502025.Hoch_0151	1.014e-239	756.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,42NWU@68525|delta/epsilon subdivisions,2WKQQ@28221|Deltaproteobacteria,2YUNI@29|Myxococcales	28221|Deltaproteobacteria	O	MreB/Mbl protein	dnaK4	-	-	-	-	-	-	-	-	-	-	-	HSP70
CMS3_k127_4092684_14	502025.Hoch_0150	5.124e-58	207.0	2CNUX@1|root,32SHU@2|Bacteria,1REYT@1224|Proteobacteria,42R1S@68525|delta/epsilon subdivisions,2WMRC@28221|Deltaproteobacteria,2YVEV@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2760)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2760
CMS3_k127_4092684_6	502025.Hoch_5811	7.444e-115	391.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4092684_8	1254432.SCE1572_11010	1.379e-105	361.0	2A4SI@1|root,30TDY@2|Bacteria,1PD6V@1224|Proteobacteria,435EQ@68525|delta/epsilon subdivisions,2X98Q@28221|Deltaproteobacteria,2Z2N2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4092684_9	502025.Hoch_5811	6.282e-103	359.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4092684_5	502025.Hoch_6761	1.214e-130	447.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,43B58@68525|delta/epsilon subdivisions,2X6IU@28221|Deltaproteobacteria,2Z3BC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_4092684_2	502025.Hoch_6762	8.174e-186	595.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,42ND4@68525|delta/epsilon subdivisions,2WKQP@28221|Deltaproteobacteria,2YUMU@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_4092684_18	502025.Hoch_6563	1.452e-27	119.0	2AREK@1|root,31GQP@2|Bacteria,1QEE8@1224|Proteobacteria,434M9@68525|delta/epsilon subdivisions,2WYYT@28221|Deltaproteobacteria,2Z0Y7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_409846_2	502025.Hoch_0379	3.946e-29	134.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,2YVBU@29|Myxococcales	28221|Deltaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
CMS3_k127_409846_1	502025.Hoch_0378	1.572e-81	276.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,2YV5Y@29|Myxococcales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_409846_0	502025.Hoch_0377	8.328e-97	319.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,2YV6W@29|Myxococcales	28221|Deltaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS3_k127_409846_3	391625.PPSIR1_36607	8.132e-25	119.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_4100205_0	502025.Hoch_3451	1.676e-261	815.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2YUHB@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS3_k127_4100205_7	483219.LILAB_24740	3.837e-25	118.0	COG1633@1|root,COG1633@2|Bacteria,1QB4C@1224|Proteobacteria,435E6@68525|delta/epsilon subdivisions,2WZRT@28221|Deltaproteobacteria,2Z2M4@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4100205_5	1313421.JHBV01000003_gene619	1.971e-29	125.0	COG3485@1|root,COG3485@2|Bacteria,4NN13@976|Bacteroidetes,1IZE6@117747|Sphingobacteriia	976|Bacteroidetes	Q	Dioxygenase	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C
CMS3_k127_4100205_8	195105.CN97_15415	4.706e-21	104.0	COG0583@1|root,COG0583@2|Bacteria,1MXR1@1224|Proteobacteria,2TRA1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K19338	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS3_k127_4100205_4	266117.Rxyl_0662	4.426e-39	168.0	COG1368@1|root,COG1368@2|Bacteria,2H4QY@201174|Actinobacteria	201174|Actinobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_4100205_3	1303518.CCALI_00164	2.566e-62	226.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4100205_1	502025.Hoch_2507	1.32e-65	250.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_4100205_6	1242864.D187_000710	5.063e-26	125.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_4100205_2	502025.Hoch_2507	1.827e-65	249.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_4107898_6	1192034.CAP_0589	4.403e-41	158.0	COG0583@1|root,COG0583@2|Bacteria,1PKXJ@1224|Proteobacteria,43447@68525|delta/epsilon subdivisions,2X551@28221|Deltaproteobacteria,2Z04I@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_4107898_7	469382.Hbor_12380	5.046e-25	109.0	COG4460@1|root,2N65Q@2157|Archaea,2Y5QA@28890|Euryarchaeota,2409H@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS3_k127_4107898_8	1121920.AUAU01000021_gene2521	1.139e-13	76.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
CMS3_k127_4107898_4	644282.Deba_0140	7.777e-52	201.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,42WA6@68525|delta/epsilon subdivisions,2WRYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,SPASM
CMS3_k127_4107898_1	404589.Anae109_3729	7.485e-197	645.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	HEAT_2,TLC,cNMP_binding
CMS3_k127_4107898_3	404589.Anae109_3728	6.609e-52	195.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	1.8.1.9	ko:K00384,ko:K10914,ko:K16922	ko00450,ko02020,ko02024,ko02025,ko02026,ko05111,map00450,map02020,map02024,map02025,map02026,map05111	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko01002,ko03000	-	-	-	cNMP_binding
CMS3_k127_4107898_2	502025.Hoch_3712	2.279e-68	245.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_4107898_0	502025.Hoch_3711	3.202e-260	822.0	COG0823@1|root,COG0823@2|Bacteria,1PFBB@1224|Proteobacteria,432XJ@68525|delta/epsilon subdivisions,2WXKI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4107898_5	1242864.D187_007309	1.608e-48	176.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2WPP7@28221|Deltaproteobacteria,2YTYB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_4108202_0	1121422.AUMW01000002_gene2258	4.126e-52	209.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_4110505_2	502025.Hoch_6493	8.675e-57	207.0	29RMJ@1|root,30CQT@2|Bacteria,1QTPA@1224|Proteobacteria,4380Z@68525|delta/epsilon subdivisions,2X3B0@28221|Deltaproteobacteria,2YV6U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4110505_1	502025.Hoch_6494	6.907e-167	554.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,1Q2EC@1224|Proteobacteria,43804@68525|delta/epsilon subdivisions,2X3A2@28221|Deltaproteobacteria,2YV2B@29|Myxococcales	28221|Deltaproteobacteria	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS3_k127_4110505_0	502025.Hoch_6495	1.513e-223	726.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUCZ@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS3_k127_4113379_15	118161.KB235922_gene2358	3.122e-21	96.0	COG0454@1|root,COG0456@2|Bacteria,1G5EH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_4113379_6	1122951.ATUE01000006_gene1049	2.523e-74	267.0	COG1893@1|root,COG1893@2|Bacteria,1N0M5@1224|Proteobacteria,1RNZY@1236|Gammaproteobacteria,3NM1M@468|Moraxellaceae	1236|Gammaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS3_k127_4113379_14	204669.Acid345_0808	5.685e-24	117.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_0808|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4113379_5	215803.DB30_4561	1.336e-88	317.0	COG0451@1|root,COG0451@2|Bacteria,1RBSM@1224|Proteobacteria,42XUG@68525|delta/epsilon subdivisions,2WTSY@28221|Deltaproteobacteria,2YX8Q@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS3_k127_4113379_8	519989.ECTPHS_09819	1.705e-55	221.0	COG1092@1|root,COG1092@2|Bacteria,1QW1V@1224|Proteobacteria,1T4CI@1236|Gammaproteobacteria,1X2QV@135613|Chromatiales	135613|Chromatiales	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_4113379_10	880073.Calab_0094	1.354e-48	194.0	COG0526@1|root,COG0526@2|Bacteria,2NRMM@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
CMS3_k127_4113379_11	502025.Hoch_5457	5.12e-46	190.0	COG0511@1|root,COG0511@2|Bacteria	2|Bacteria	I	ligase activity, forming carbon-carbon bonds	accB	-	2.3.1.12,2.3.1.39,4.1.1.3	ko:K00627,ko:K00645,ko:K01572,ko:K02160	ko00010,ko00020,ko00061,ko00333,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00333,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00217,R00742,R01626,R02569,R11671	RC00004,RC00039,RC00040,RC00367,RC02727,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko01004,ko02000	3.B.1.1.1	-	-	Acyl_transf_1,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_4113379_0	502025.Hoch_5456	0.0	1007.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria,42P34@68525|delta/epsilon subdivisions,2WK9S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM carboxyl transferase	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
CMS3_k127_4113379_1	502025.Hoch_2088	6.17e-221	692.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUJ1@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS3_k127_4113379_12	1828.JOKB01000061_gene1816	5.181e-32	143.0	2EWTS@1|root,33Q5B@2|Bacteria,2HZQX@201174|Actinobacteria,4FXWW@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4113379_2	379066.GAU_0803	8.408e-187	615.0	COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4113379_3	391625.PPSIR1_41684	1.736e-156	517.0	COG0810@1|root,COG4402@1|root,COG0810@2|Bacteria,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_4113379_9	439235.Dalk_0248	7.671e-53	199.0	COG3327@1|root,COG3327@2|Bacteria,1RABS@1224|Proteobacteria	1224|Proteobacteria	K	COG3327 Phenylacetic acid-responsive transcriptional repressor	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
CMS3_k127_4113379_7	398525.KB900701_gene4519	4.215e-71	250.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,2TSTR@28211|Alphaproteobacteria,3JTTJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Fatty acid desaturase	MA20_28095	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS3_k127_4113379_4	502025.Hoch_6429	2.546e-122	399.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,42YFC@68525|delta/epsilon subdivisions,2WU03@28221|Deltaproteobacteria,2YUBP@29|Myxococcales	28221|Deltaproteobacteria	I	desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_4113379_13	1210884.HG799463_gene9888	1.012e-30	136.0	COG2706@1|root,COG3209@1|root,COG4719@1|root,COG2706@2|Bacteria,COG3209@2|Bacteria,COG4719@2|Bacteria,2J4YJ@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_4120603_0	861299.J421_4338	6.381e-39	163.0	COG0457@1|root,COG0457@2|Bacteria,1ZU8U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_4120603_2	469604.HMPREF0946_00718	1.698e-13	83.0	COG2885@1|root,COG2885@2|Bacteria,379ZG@32066|Fusobacteria	32066|Fusobacteria	M	OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA,YadA_anchor,YadA_head,YadA_stalk
CMS3_k127_4120603_1	502025.Hoch_6061	1.445e-16	87.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2YW5U@29|Myxococcales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS3_k127_4120603_3	574087.Acear_2216	6.119e-10	60.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WADA@53433|Halanaerobiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_4121889_13	502025.Hoch_5596	2.06e-32	145.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_4121889_10	1297742.A176_02689	3.545e-34	145.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,2YVTX@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS3_k127_4121889_5	502025.Hoch_5592	3.12e-75	266.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,2YVG8@29|Myxococcales	28221|Deltaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS3_k127_4121889_11	502025.Hoch_5591	4.411e-34	136.0	COG0737@1|root,COG0737@2|Bacteria,1QXU9@1224|Proteobacteria,43C6T@68525|delta/epsilon subdivisions,2X7H0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_4121889_7	502025.Hoch_2732	2.897e-64	225.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS3_k127_4121889_4	483219.LILAB_22845	4.234e-104	351.0	COG3320@1|root,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,42W94@68525|delta/epsilon subdivisions,2WR9E@28221|Deltaproteobacteria,2YUNG@29|Myxococcales	28221|Deltaproteobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
CMS3_k127_4121889_0	886293.Sinac_1156	4.359e-280	903.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4121889_9	1177154.Y5S_01444	4.809e-41	173.0	COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria,1S4N1@1236|Gammaproteobacteria,1XJTF@135619|Oceanospirillales	135619|Oceanospirillales	O	COG0625 Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N_3
CMS3_k127_4121889_3	448385.sce6656	1.308e-115	387.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	2|Bacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4121889_2	502025.Hoch_0390	2.667e-198	623.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2YWEI@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS3_k127_4121889_12	502025.Hoch_0391	2.318e-33	148.0	2DHU7@1|root,300Z2@2|Bacteria,1Q940@1224|Proteobacteria,433U6@68525|delta/epsilon subdivisions,2X3GR@28221|Deltaproteobacteria,2YW0V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
CMS3_k127_4121889_1	502025.Hoch_0392	3.786e-269	834.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YTUT@29|Myxococcales	28221|Deltaproteobacteria	O	heat shock protein 70	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_4128876_3	1192034.CAP_2176	1.468e-41	160.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YY6R@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS3_k127_4128876_1	292459.STH413	4.254e-109	385.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,247Q5@186801|Clostridia	186801|Clostridia	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,CMD,E3_binding
CMS3_k127_4128876_0	290397.Adeh_1826	7.617e-159	506.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2YTX4@29|Myxococcales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_4128876_2	1192034.CAP_6081	9.577e-60	212.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YV62@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS3_k127_414045_1	1449351.RISW2_05205	2.753e-08	62.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,4KKII@93682|Roseivivax	28211|Alphaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS3_k127_414045_0	751944.HALDL1_10145	2.474e-31	136.0	COG0596@1|root,arCOG01648@2157|Archaea,2XUNG@28890|Euryarchaeota,23SVU@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	catD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_4146863_4	391625.PPSIR1_22886	1.326e-51	196.0	COG2199@1|root,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X7CV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
CMS3_k127_4146863_1	502025.Hoch_2471	1.147e-86	295.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2YUYM@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS3_k127_4146863_0	404589.Anae109_0776	2.827e-126	426.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2YTSW@29|Myxococcales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
CMS3_k127_4146863_12	1245471.PCA10_23210	2.517e-07	62.0	COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S4IP@1236|Gammaproteobacteria,1YKI2@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
CMS3_k127_4146863_11	391625.PPSIR1_31713	1.036e-07	64.0	COG0457@1|root,COG0457@2|Bacteria	391625.PPSIR1_31713|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4146863_2	502025.Hoch_0497	8.399e-69	252.0	COG0515@1|root,COG3416@1|root,COG0515@2|Bacteria,COG3416@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_4146863_6	765420.OSCT_1861	3.708e-28	133.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_4146863_5	1278073.MYSTI_07503	1.894e-46	182.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_4146863_7	1121377.KB906400_gene1263	5.303e-23	103.0	2ED10@1|root,336XY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4146863_3	29306.JOBE01000067_gene3691	3.848e-60	216.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS3_k127_4146863_9	627192.SLG_10440	3.25e-13	70.0	COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2UKNY@28211|Alphaproteobacteria,2K64H@204457|Sphingomonadales	204457|Sphingomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS3_k127_4156493_2	502025.Hoch_2064	3.098e-97	349.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,42PQ6@68525|delta/epsilon subdivisions,2WJHR@28221|Deltaproteobacteria,2YV9V@29|Myxococcales	28221|Deltaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_4156493_0	96561.Dole_1921	1.487e-162	520.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,42NKV@68525|delta/epsilon subdivisions,2WKPA@28221|Deltaproteobacteria,2MIDW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4156493_3	439235.Dalk_0100	1.33e-38	164.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,42TAR@68525|delta/epsilon subdivisions,2WPQT@28221|Deltaproteobacteria,2MKA0@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_4156493_6	391625.PPSIR1_23659	0.0001793	55.0	COG0515@1|root,COG0515@2|Bacteria	391625.PPSIR1_23659|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4156493_1	448385.sce8739	2.487e-115	394.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,4380T@68525|delta/epsilon subdivisions,2X3AT@28221|Deltaproteobacteria,2YZH7@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4156493_4	658086.HMPREF0994_04801	2.076e-08	67.0	COG4409@1|root,COG4409@2|Bacteria,1V5Q1@1239|Firmicutes,24FGZ@186801|Clostridia,27R3R@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 32 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
CMS3_k127_4156493_5	448385.sce8599	2.856e-05	46.0	2A4BQ@1|root,30SXD@2|Bacteria,1PCFN@1224|Proteobacteria,438EV@68525|delta/epsilon subdivisions,2WYPE@28221|Deltaproteobacteria,2YWSY@29|Myxococcales	28221|Deltaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
CMS3_k127_4162094_1	502025.Hoch_4470	5.859e-65	232.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,43CGP@68525|delta/epsilon subdivisions,2X7RU@28221|Deltaproteobacteria,2YV1F@29|Myxococcales	28221|Deltaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CMS3_k127_4162094_0	502025.Hoch_4469	1.519e-173	555.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2YUGA@29|Myxococcales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS3_k127_4171563_20	1121396.KB893090_gene202	1.963e-26	126.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria,2MKTC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_4171563_19	479434.Sthe_1828	9.311e-32	130.0	COG5483@1|root,COG5483@2|Bacteria,2G97B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
CMS3_k127_4171563_31	457429.ABJI02000189_gene5987	3.008e-06	61.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_4171563_3	1192034.CAP_7430	1.231e-77	282.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria,2YUVI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4171563_35	1192034.CAP_2668	0.00023	53.0	COG1470@1|root,COG1470@2|Bacteria,1QZIJ@1224|Proteobacteria,43CK1@68525|delta/epsilon subdivisions,2X7UG@28221|Deltaproteobacteria,2YY6W@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_4171563_21	391625.PPSIR1_07997	9.22e-25	123.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_4171563_9	404380.Gbem_2063	4.055e-59	236.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_4171563_32	573370.DMR_12650	1.025e-05	54.0	2DSJI@1|root,33GEP@2|Bacteria,1N39S@1224|Proteobacteria,42UW5@68525|delta/epsilon subdivisions,2WR68@28221|Deltaproteobacteria,2MC9J@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
CMS3_k127_4171563_8	682795.AciX8_1487	7.823e-62	227.0	COG0535@1|root,COG0535@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_4171563_27	335543.Sfum_4010	1.406e-07	64.0	COG1117@1|root,COG1117@2|Bacteria,1NMB4@1224|Proteobacteria,42XIZ@68525|delta/epsilon subdivisions,2WTEA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4171563_11	483219.LILAB_32280	6.396e-53	216.0	COG0457@1|root,COG2956@1|root,COG3118@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3118@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
CMS3_k127_4171563_7	391625.PPSIR1_21929	1.249e-64	239.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA,VWA_2
CMS3_k127_4171563_18	1192034.CAP_1968	7.994e-35	141.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YWI7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
CMS3_k127_4171563_23	1121360.AUAQ01000013_gene2376	7.369e-11	71.0	COG1283@1|root,COG1283@2|Bacteria,2IAMX@201174|Actinobacteria,22JVK@1653|Corynebacteriaceae	201174|Actinobacteria	P	phosphate symporter	nptA	-	-	ko:K03324,ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1,2.A.58.2	-	-	Na_Pi_cotrans
CMS3_k127_4171563_17	118168.MC7420_6212	4.789e-38	157.0	COG0580@1|root,COG0580@2|Bacteria,1G0AW@1117|Cyanobacteria,1H75V@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
CMS3_k127_4171563_29	156889.Mmc1_2267	2.455e-07	57.0	COG0265@1|root,COG0265@2|Bacteria,1NTJ8@1224|Proteobacteria	1224|Proteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_4171563_1	573370.DMR_40750	9.351e-124	412.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42PMJ@68525|delta/epsilon subdivisions,2X5FZ@28221|Deltaproteobacteria,2MGQC@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
CMS3_k127_4171563_36	1403819.BATR01000031_gene1006	0.0003157	46.0	2EUQE@1|root,33N63@2|Bacteria,46XGX@74201|Verrucomicrobia,2IVVX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339
CMS3_k127_4171563_33	1517416.IDAT_05385	7.166e-05	56.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,1RVNC@1236|Gammaproteobacteria,2QF9P@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	membrane transporter protein	Z012_10580	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_4171563_24	156889.Mmc1_2254	3.667e-10	73.0	COG0265@1|root,COG0265@2|Bacteria,1NZFR@1224|Proteobacteria,2USTQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4171563_22	944479.JQLX01000013_gene1378	1.523e-22	112.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2M6HW@213113|Desulfurellales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS3_k127_4171563_28	316274.Haur_3469	1.654e-07	61.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,2GBDY@200795|Chloroflexi,375DC@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
CMS3_k127_4171563_13	156889.Mmc1_2250	9.328e-50	188.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	MA20_15190	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS3_k127_4171563_15	1430440.MGMSRv2_2375	2.333e-43	171.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	MA20_15190	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS3_k127_4171563_34	41431.PCC8801_0384	0.0001084	54.0	COG0265@1|root,COG0265@2|Bacteria,1G17C@1117|Cyanobacteria,3KGV2@43988|Cyanothece	1117|Cyanobacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	hhoA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_4171563_30	1126627.BAWE01000004_gene2727	9.041e-07	59.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3JQQI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	MA20_07235	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_4171563_10	1121106.JQKB01000044_gene4715	5.842e-57	216.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2JQVG@204441|Rhodospirillales	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_4171563_5	926562.Oweho_3443	4.821e-77	278.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2PA7T@246874|Cryomorphaceae	976|Bacteroidetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4171563_2	85643.Tmz1t_2954	6.35e-82	286.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,2VP5E@28216|Betaproteobacteria,2KVHQ@206389|Rhodocyclales	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_4171563_16	502025.Hoch_6594	4.065e-38	150.0	COG2426@1|root,COG2426@2|Bacteria,1PB7N@1224|Proteobacteria,432PT@68525|delta/epsilon subdivisions,2WYBP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
CMS3_k127_4171563_4	518766.Rmar_0797	1.736e-77	276.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJWW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4171563_12	1244869.H261_19169	3.5e-52	208.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,2V6WW@28211|Alphaproteobacteria,2JRJU@204441|Rhodospirillales	204441|Rhodospirillales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS3_k127_4171563_25	290397.Adeh_0249	7.41e-09	68.0	COG1413@1|root,COG1413@2|Bacteria,1QX4H@1224|Proteobacteria,42Z02@68525|delta/epsilon subdivisions,2WUJ9@28221|Deltaproteobacteria,2YVP1@29|Myxococcales	28221|Deltaproteobacteria	C	Type II secretion system (T2SS), protein E, N-terminal domain	frgA	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,T2SSE_N
CMS3_k127_4171563_26	1283300.ATXB01000001_gene2084	1.681e-08	68.0	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria,1XFER@135618|Methylococcales	135618|Methylococcales	M	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
CMS3_k127_4171563_6	243231.GSU0099	9.638e-68	235.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
CMS3_k127_4231460_0	1254432.SCE1572_32540	1.919e-51	207.0	COG5184@1|root,COG5184@2|Bacteria,1R0CH@1224|Proteobacteria,43CUZ@68525|delta/epsilon subdivisions,2X82R@28221|Deltaproteobacteria,2Z1VU@29|Myxococcales	28221|Deltaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4231460_1	1487953.JMKF01000088_gene5446	1.906e-24	120.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1G08F@1117|Cyanobacteria,1H8J6@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SBBP
CMS3_k127_425729_4	502025.Hoch_6845	3.771e-05	48.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,43AG6@68525|delta/epsilon subdivisions,2X63V@28221|Deltaproteobacteria,2Z0GY@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_425729_3	502025.Hoch_6453	3.061e-45	177.0	28W5H@1|root,2ZI6A@2|Bacteria,1QBFX@1224|Proteobacteria,435GD@68525|delta/epsilon subdivisions,2WZTW@28221|Deltaproteobacteria,2Z2QX@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS3_k127_425729_2	502025.Hoch_6454	2.788e-101	341.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,2YV17@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS3_k127_425729_0	1232410.KI421422_gene2090	1.57e-317	1006.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,43SBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ABC transporter	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_425729_1	502025.Hoch_2081	1.306e-116	377.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2Z1X0@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_4261829_3	502025.Hoch_2466	7.563e-11	76.0	2CDR8@1|root,32ZSF@2|Bacteria,1NCBG@1224|Proteobacteria,42V4S@68525|delta/epsilon subdivisions,2WSDP@28221|Deltaproteobacteria,2YVN6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4261829_2	357808.RoseRS_3593	1.134e-51	207.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi,37519@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
CMS3_k127_4261829_0	502025.Hoch_3643	1.158e-145	477.0	COG0455@1|root,COG0484@1|root,COG1426@1|root,COG0455@2|Bacteria,COG0484@2|Bacteria,COG1426@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2YUZU@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
CMS3_k127_4261829_1	1125863.JAFN01000001_gene282	1.165e-61	220.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS3_k127_426922_0	502025.Hoch_1608	6.365e-132	439.0	COG4249@1|root,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions,2WRUQ@28221|Deltaproteobacteria,2Z389@29|Myxococcales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS3_k127_426922_13	215803.DB30_1553	3.319e-42	172.0	COG5662@1|root,COG5662@2|Bacteria,1Q39S@1224|Proteobacteria,4390Y@68525|delta/epsilon subdivisions,2X465@28221|Deltaproteobacteria,2YYC2@29|Myxococcales	28221|Deltaproteobacteria	K	AntiSigma factor	actD	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_426922_10	1278073.MYSTI_00236	1.358e-52	190.0	COG1595@1|root,COG1595@2|Bacteria,1RHSF@1224|Proteobacteria,438JV@68525|delta/epsilon subdivisions,2X3UH@28221|Deltaproteobacteria,2YX4W@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HTH_24,Sigma70_r2,Sigma70_r4_2
CMS3_k127_426922_19	880073.Calab_1728	5.367e-06	59.0	COG2374@1|root,COG2374@2|Bacteria,2NRBP@2323|unclassified Bacteria	2|Bacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_426922_4	502025.Hoch_3588	2.705e-90	313.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,43190@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Fructosamine kinase	yniA	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CMS3_k127_426922_9	502025.Hoch_3589	2.067e-56	201.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42RY9@68525|delta/epsilon subdivisions,2WW61@28221|Deltaproteobacteria,2Z2RX@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_426922_20	641526.ADIWIN_1403	7.799e-06	57.0	COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,1HXI1@117743|Flavobacteriia	976|Bacteroidetes	O	peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
CMS3_k127_426922_16	1385517.N800_14665	6.703e-35	138.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1T5A0@1236|Gammaproteobacteria,1XDFF@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_426922_11	1254432.SCE1572_31010	2.004e-50	195.0	COG4402@1|root,COG4402@2|Bacteria,1QA5C@1224|Proteobacteria,434UU@68525|delta/epsilon subdivisions,2WZ5W@28221|Deltaproteobacteria,2Z1E4@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_426922_2	391625.PPSIR1_21719	1.966e-106	366.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CMS3_k127_426922_12	134676.ACPL_1561	2.482e-42	173.0	COG0557@1|root,COG0557@2|Bacteria,2GNSM@201174|Actinobacteria,4D9VN@85008|Micromonosporales	201174|Actinobacteria	K	RNB	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
CMS3_k127_426922_14	1205680.CAKO01000002_gene3100	3.721e-36	145.0	COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,2U72Z@28211|Alphaproteobacteria,2JXG0@204441|Rhodospirillales	204441|Rhodospirillales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_426922_15	1144275.COCOR_00077	3.597e-35	155.0	COG2050@1|root,COG2050@2|Bacteria,1RITB@1224|Proteobacteria,434FY@68525|delta/epsilon subdivisions,2X8VI@28221|Deltaproteobacteria,2Z0DN@29|Myxococcales	28221|Deltaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_426922_5	349163.Acry_0578	9.378e-89	312.0	COG0784@1|root,COG2461@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2461@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2JQV2@204441|Rhodospirillales	204441|Rhodospirillales	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_426922_1	448385.sce6976	7.417e-127	432.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K01932,ko:K03301	-	-	-	-	ko00000,ko01000	2.A.12	-	-	Glyco_transf_4,Glycos_transf_1,HEAT_2,TLC
CMS3_k127_426922_17	448385.sce6264	3.232e-12	79.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
CMS3_k127_426922_3	502025.Hoch_5811	3.538e-106	366.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4278341_6	1255043.TVNIR_1929	9.994e-66	227.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,1WVXE@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS3_k127_4278341_7	1142394.PSMK_04200	1.044e-65	234.0	COG1091@1|root,COG1091@2|Bacteria,2IZ38@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS3_k127_4278341_10	688245.CtCNB1_2755	7.55e-62	232.0	COG0438@1|root,COG0438@2|Bacteria,1NEWI@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4278341_12	688245.CtCNB1_2754	1.756e-36	157.0	2F6YM@1|root,33ZEM@2|Bacteria,1NXZX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_29
CMS3_k127_4278341_18	290397.Adeh_4027	2.101e-17	96.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4278341_15	502025.Hoch_3460	6.644e-26	116.0	COG0577@1|root,COG0577@2|Bacteria,1QXV8@1224|Proteobacteria,43C7Z@68525|delta/epsilon subdivisions,2X7IB@28221|Deltaproteobacteria,2YUZK@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CMS3_k127_4278341_2	903818.KI912268_gene1425	2.045e-107	374.0	COG4191@1|root,COG4191@2|Bacteria,3Y2IQ@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
CMS3_k127_4278341_5	391625.PPSIR1_41239	2.376e-72	267.0	COG0515@1|root,COG0515@2|Bacteria	391625.PPSIR1_41239|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4278341_4	768710.DesyoDRAFT_1775	5.871e-103	357.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4278341_20	1382306.JNIM01000001_gene4226	1.108e-09	71.0	COG0789@1|root,COG0789@2|Bacteria,2G9I9@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_4278341_11	1394178.AWOO02000009_gene4351	2.345e-54	203.0	COG0596@1|root,COG0596@2|Bacteria,2I6D8@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4278341_8	439235.Dalk_0030	1.515e-64	243.0	COG0596@1|root,COG1032@1|root,COG0596@2|Bacteria,COG1032@2|Bacteria,1RJ9Z@1224|Proteobacteria,42TDD@68525|delta/epsilon subdivisions,2WPHS@28221|Deltaproteobacteria,2MK5Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Radical_SAM
CMS3_k127_4278341_1	429009.Adeg_0556	1.272e-108	365.0	COG1239@1|root,COG1239@2|Bacteria,1UHYK@1239|Firmicutes,24BJ0@186801|Clostridia,42ESQ@68295|Thermoanaerobacterales	186801|Clostridia	H	Magnesium chelatase, subunit ChlI	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
CMS3_k127_4278341_16	1203605.HMPREF1531_00443	2.367e-21	110.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,2GN3S@201174|Actinobacteria,4DN4R@85009|Propionibacteriales	201174|Actinobacteria	H	subunit ChlI	bchI_2	-	6.6.1.1	ko:K03404	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
CMS3_k127_4278341_17	404589.Anae109_3979	2.152e-18	100.0	2C4SZ@1|root,344GS@2|Bacteria,1P2T8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4278341_3	502025.Hoch_5811	1.933e-104	359.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4278341_19	1192034.CAP_6467	6.813e-10	70.0	COG1262@1|root,COG1361@1|root,COG3055@1|root,COG5184@1|root,COG1262@2|Bacteria,COG1361@2|Bacteria,COG3055@2|Bacteria,COG5184@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4278341_0	502025.Hoch_4145	5.325e-232	758.0	COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4278341_9	1122604.JONR01000008_gene2236	2.113e-63	233.0	28WH1@1|root,2ZIH5@2|Bacteria,1R9QX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4278341_13	1166018.FAES_5442	4.395e-29	129.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
CMS3_k127_4278341_14	1323361.JPOC01000072_gene3104	1.025e-28	125.0	COG2730@1|root,COG2730@2|Bacteria,2HQAQ@201174|Actinobacteria,4FZ33@85025|Nocardiaceae	201174|Actinobacteria	G	Beta-galactosidase	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
CMS3_k127_4291192_9	380358.XALC_0934	7.526e-90	314.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RWVV@1236|Gammaproteobacteria,1XAIA@135614|Xanthomonadales	135614|Xanthomonadales	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_4291192_15	502025.Hoch_6875	5.595e-34	135.0	COG0745@1|root,COG0745@2|Bacteria,1RKDZ@1224|Proteobacteria,43F04@68525|delta/epsilon subdivisions,2WYKX@28221|Deltaproteobacteria,2Z1YF@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_4291192_6	391625.PPSIR1_36227	2.105e-115	390.0	COG1126@1|root,COG1126@2|Bacteria	2|Bacteria	E	abc transporter atp-binding protein	-	-	-	ko:K10038	ko02010,map02010	M00227	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.2	-	-	ABC_tran
CMS3_k127_4291192_4	1242864.D187_006469	1.87e-121	398.0	COG0596@1|root,COG0596@2|Bacteria,1REXZ@1224|Proteobacteria,43AQG@68525|delta/epsilon subdivisions,2X64D@28221|Deltaproteobacteria,2YZ99@29|Myxococcales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
CMS3_k127_4291192_8	1234595.C725_0839	4.18e-105	362.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,4BP8H@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_4291192_11	248742.XP_005643837.1	1.739e-72	251.0	COG4586@1|root,KOG2355@2759|Eukaryota,37PFS@33090|Viridiplantae,34HGZ@3041|Chlorophyta	3041|Chlorophyta	K	ABC transporter	-	-	-	ko:K12608	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019	-	-	-	ABC_tran
CMS3_k127_4291192_0	502025.Hoch_1373	2.685e-235	755.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,438BA@68525|delta/epsilon subdivisions,2X3KK@28221|Deltaproteobacteria,2YWFN@29|Myxococcales	28221|Deltaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS3_k127_4291192_17	1163409.UUA_11953	1.187e-15	91.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_4291192_12	378806.STAUR_0481	2.783e-59	212.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42URE@68525|delta/epsilon subdivisions,2X3JC@28221|Deltaproteobacteria,2YWB8@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4291192_20	700598.Niako_6950	5.384e-06	58.0	COG4922@1|root,COG4922@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
CMS3_k127_4291192_21	616991.JPOO01000003_gene984	1.661e-05	57.0	COG5485@1|root,COG5485@2|Bacteria,4PNKP@976|Bacteroidetes,1IK8M@117743|Flavobacteriia	976|Bacteroidetes	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_4291192_16	391625.PPSIR1_30474	2.682e-33	143.0	COG0745@1|root,COG0745@2|Bacteria	391625.PPSIR1_30474|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4291192_13	502025.Hoch_6335	2.241e-54	202.0	COG2979@1|root,COG2979@2|Bacteria	2|Bacteria	T	Protein of unknown function (DUF533)	-	-	-	ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	PG_binding_4,TerB,VanW
CMS3_k127_4291192_5	502025.Hoch_5713	5.924e-118	389.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2YVA6@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_4291192_1	502025.Hoch_5714	1.235e-158	526.0	COG1257@1|root,COG1257@2|Bacteria,1MXVE@1224|Proteobacteria,42R5Q@68525|delta/epsilon subdivisions,2WN6K@28221|Deltaproteobacteria,2YTT9@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
CMS3_k127_4291192_10	448385.sce3011	9.156e-86	307.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2YU8C@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_4291192_7	502025.Hoch_5716	2.623e-106	371.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,42S21@68525|delta/epsilon subdivisions,2WNRS@28221|Deltaproteobacteria,2YV7S@29|Myxococcales	28221|Deltaproteobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K01851,ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
CMS3_k127_4291192_3	502025.Hoch_5717	3.243e-132	445.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,42PNC@68525|delta/epsilon subdivisions,2WKSZ@28221|Deltaproteobacteria,2YUJF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
CMS3_k127_4291192_14	502025.Hoch_5610	1.833e-41	177.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,43BQ1@68525|delta/epsilon subdivisions,2X718@28221|Deltaproteobacteria,2Z3MK@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
CMS3_k127_4291192_2	983917.RGE_37240	7.876e-136	436.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2VJ36@28216|Betaproteobacteria,1KKKJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661,ko:K07536	ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220	M00116,M00540	R05592,R07263	RC01429,RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_4291326_12	631362.Thi970DRAFT_03359	2.592e-67	234.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,1WWYI@135613|Chromatiales	135613|Chromatiales	C	Aldehyde	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS3_k127_4291326_30	926564.KI911619_gene3994	0.0001393	52.0	COG0589@1|root,COG0589@2|Bacteria,2HF2A@201174|Actinobacteria,4F4R5@85017|Promicromonosporaceae	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_4291326_16	1227739.Hsw_3983	2.303e-49	183.0	2E4YY@1|root,32ZSQ@2|Bacteria,4P5XB@976|Bacteroidetes,47W1A@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4291326_11	1005048.CFU_3307	1.698e-73	262.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,4723B@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_4291326_7	215803.DB30_6882	6.226e-116	396.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4291326_23	1192034.CAP_1968	1.109e-20	105.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YWI7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
CMS3_k127_4291326_6	502025.Hoch_0262	2.464e-130	435.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_4291326_9	391625.PPSIR1_22074	1.274e-92	316.0	COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria	1224|Proteobacteria	I	fatty acid desaturase	desA3	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_4291326_1	391625.PPSIR1_25656	3.929e-239	752.0	COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42Q23@68525|delta/epsilon subdivisions,2WWQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_4291326_18	502025.Hoch_6795	8.6e-36	155.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_4291326_2	391625.PPSIR1_25641	7.006e-212	668.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_4291326_10	483219.LILAB_10430	2.063e-74	286.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YY0K@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
CMS3_k127_4291326_5	1192034.CAP_3557	5.216e-140	456.0	COG0535@1|root,COG0535@2|Bacteria,1NDTC@1224|Proteobacteria	1224|Proteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_4291326_4	1192034.CAP_2191	3.801e-157	499.0	COG0535@1|root,COG0535@2|Bacteria,1QAR5@1224|Proteobacteria,4358Z@68525|delta/epsilon subdivisions,2WZK5@28221|Deltaproteobacteria,2Z2AQ@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_4291326_14	391625.PPSIR1_25666	2.93e-65	256.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	mftB	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Radical_SAM
CMS3_k127_4291326_8	391625.PPSIR1_25681	3.924e-107	357.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_4291326_3	1192034.CAP_3559	8.491e-177	572.0	COG0535@1|root,COG2896@1|root,COG0535@2|Bacteria,COG2896@2|Bacteria	2|Bacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	-	-	2.7.1.121,4.1.99.22	ko:K02585,ko:K03639,ko:K05879	ko00561,ko00790,ko01100,ko04122,map00561,map00790,map01100,map04122	-	R01012,R09394	RC00015,RC00017,RC03420	ko00000,ko00001,ko01000	-	-	-	Dak2,Fer4_12,Glycos_transf_2,Nitro_FeMo-Co,Radical_SAM,SPASM
CMS3_k127_4291326_13	1131269.AQVV01000008_gene942	1.59e-66	246.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4291326_27	641491.DND132_1651	1.427e-08	69.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2M7W0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_4291326_24	1382230.ASAP_0842	1.466e-13	81.0	COG3394@1|root,COG3394@2|Bacteria,1PP39@1224|Proteobacteria,2U2UW@28211|Alphaproteobacteria,2JSGS@204441|Rhodospirillales	204441|Rhodospirillales	G	YdjC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
CMS3_k127_4291326_17	1123367.C666_04705	2.371e-39	156.0	COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,2WGWG@28216|Betaproteobacteria,2KZQC@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4291326_29	1385520.N802_04015	0.0001223	53.0	COG0382@1|root,COG0382@2|Bacteria,2IJV5@201174|Actinobacteria	201174|Actinobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_4291326_19	439235.Dalk_5124	6.091e-35	153.0	COG0535@1|root,COG0535@2|Bacteria,1PCDW@1224|Proteobacteria,430T3@68525|delta/epsilon subdivisions,2WW5X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_4291326_28	1410620.SHLA_9c000240	1.367e-06	63.0	COG0457@1|root,COG0457@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_4291326_22	221103.XP_007842434.1	4.304e-22	115.0	2CV03@1|root,2RQ0Y@2759|Eukaryota,39Y46@33154|Opisthokonta,3PBM9@4751|Fungi,3V3KR@5204|Basidiomycota,226A4@155619|Agaricomycetes,3W4JJ@5338|Agaricales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_4291326_0	391625.PPSIR1_25706	0.0	1018.0	COG0535@1|root,COG1032@1|root,COG0535@2|Bacteria,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_430392_3	391625.PPSIR1_13215	5.163e-07	61.0	COG0457@1|root,COG0457@2|Bacteria	391625.PPSIR1_13215|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_430392_4	391625.PPSIR1_13215	0.0001322	55.0	COG0457@1|root,COG0457@2|Bacteria	391625.PPSIR1_13215|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_430392_1	502025.Hoch_6688	8.432e-37	150.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,42WT6@68525|delta/epsilon subdivisions,2WSN5@28221|Deltaproteobacteria,2YVN7@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
CMS3_k127_430392_0	502025.Hoch_6687	1.165e-125	418.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
CMS3_k127_4339803_14	1192034.CAP_7971	4.847e-11	78.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,RCC1_2
CMS3_k127_4339803_4	502025.Hoch_4901	4.44e-109	398.0	COG2885@1|root,COG2885@2|Bacteria,1NRFN@1224|Proteobacteria,43CZ4@68525|delta/epsilon subdivisions,2X87C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS3_k127_4339803_7	502025.Hoch_4696	5.645e-91	330.0	COG4254@1|root,COG4254@2|Bacteria,1QX4F@1224|Proteobacteria,43BX2@68525|delta/epsilon subdivisions,2X77V@28221|Deltaproteobacteria,2YX6H@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS3_k127_4339803_10	378806.STAUR_7662	3.864e-55	220.0	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4339803_9	502025.Hoch_4948	1.471e-82	296.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,434N1@68525|delta/epsilon subdivisions,2WYZF@28221|Deltaproteobacteria,2Z0ZV@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_4339803_13	357808.RoseRS_1736	5.804e-14	85.0	COG1413@1|root,COG1674@1|root,COG5635@1|root,COG1413@2|Bacteria,COG1674@2|Bacteria,COG5635@2|Bacteria,2G8R0@200795|Chloroflexi,3766B@32061|Chloroflexia	32061|Chloroflexia	CDT	Armadillo/beta-catenin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_4339803_22	391625.PPSIR1_42144	4.873e-05	56.0	COG0810@1|root,COG0810@2|Bacteria,1QGPT@1224|Proteobacteria,434QY@68525|delta/epsilon subdivisions,2WZ24@28221|Deltaproteobacteria,2Z15Z@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4339803_15	1144275.COCOR_03961	3.512e-10	70.0	COG2374@1|root,COG3568@1|root,COG2374@2|Bacteria,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	XK27_02140	-	3.2.1.4	ko:K01179,ko:K07004	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	5_nucleotid_C,CHB_HEX_C_1,Calx-beta,Exo_endo_phos,Gram_pos_anchor,HemolysinCabind,LTD,Metallophos,SLH
CMS3_k127_4339803_0	502025.Hoch_4573	2.882e-211	715.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
CMS3_k127_4339803_6	502025.Hoch_4949	3.935e-92	310.0	COG0558@1|root,COG0558@2|Bacteria,1NJC1@1224|Proteobacteria,42XU7@68525|delta/epsilon subdivisions,2WT69@28221|Deltaproteobacteria,2Z0YR@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_4339803_11	1096769.Pelub83DRAFT_0203	5.598e-51	199.0	COG1213@1|root,COG1396@1|root,COG1213@2|Bacteria,COG1396@2|Bacteria,1RB54@1224|Proteobacteria,2U5XC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS3_k127_4339803_21	1242864.D187_003099	3.661e-07	61.0	COG1506@1|root,COG2885@1|root,COG1506@2|Bacteria,COG2885@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_4339803_19	449447.MAE_21930	1.554e-08	66.0	2DU7S@1|root,33P96@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4339803_17	1123242.JH636436_gene211	2.786e-09	69.0	COG1547@1|root,COG1547@2|Bacteria,2J0JA@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF309
CMS3_k127_4339803_16	1223523.H340_28255	3.557e-10	68.0	COG0517@1|root,COG2823@1|root,COG0517@2|Bacteria,COG2823@2|Bacteria,2GKSH@201174|Actinobacteria	201174|Actinobacteria	C	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
CMS3_k127_4339803_5	502025.Hoch_6429	3.856e-106	352.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,42YFC@68525|delta/epsilon subdivisions,2WU03@28221|Deltaproteobacteria,2YUBP@29|Myxococcales	28221|Deltaproteobacteria	I	desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_4339803_1	1144275.COCOR_05087	3.319e-164	524.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42QAU@68525|delta/epsilon subdivisions,2WMD2@28221|Deltaproteobacteria,2YUNE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K11731	ko00281,map00281	-	R08089	RC01893	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4339803_8	502025.Hoch_4952	4.195e-87	295.0	COG0745@1|root,COG0745@2|Bacteria,1QVDV@1224|Proteobacteria,43APF@68525|delta/epsilon subdivisions,2X631@28221|Deltaproteobacteria,2Z38J@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
CMS3_k127_4339803_2	502025.Hoch_3956	1.614e-130	432.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4339803_3	378806.STAUR_7772	1.926e-117	415.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43CAN@68525|delta/epsilon subdivisions,2X7M5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8,PAS,PAS_8,Sigma54_activat
CMS3_k127_4339803_18	1192034.CAP_4581	9.953e-09	65.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
CMS3_k127_4340140_0	1121957.ATVL01000009_gene1201	3.273e-124	413.0	COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,47KG2@768503|Cytophagia	976|Bacteroidetes	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
CMS3_k127_4340140_1	1206741.BAFX01000095_gene4637	4.634e-28	125.0	2EWTS@1|root,33Q5B@2|Bacteria,2HZQX@201174|Actinobacteria,4FXWW@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4353197_6	502025.Hoch_5344	2.37e-07	53.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2YU9T@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS3_k127_4353197_4	1242864.D187_002767	2.878e-50	195.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42PZQ@68525|delta/epsilon subdivisions,2WK7D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA,HD,HD_5,Response_reg
CMS3_k127_4353197_0	323850.Shew_3096	6.603e-93	315.0	COG3291@1|root,COG3291@2|Bacteria,1NE5Q@1224|Proteobacteria,1TCNR@1236|Gammaproteobacteria,2Q8VQ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
CMS3_k127_4353197_5	67267.JNXT01000003_gene4061	2.505e-26	123.0	2AS7Y@1|root,31HKZ@2|Bacteria,2I9TF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4353197_1	502025.Hoch_5342	1.147e-86	316.0	COG0784@1|root,COG1196@1|root,COG0784@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	frzS	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg
CMS3_k127_4353197_7	1278073.MYSTI_03804	2.572e-06	58.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_4353197_2	502025.Hoch_5340	1.043e-76	266.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	2|Bacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4353197_3	502025.Hoch_5339	1.748e-69	238.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2YU7F@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_4356352_1	502025.Hoch_2647	6.736e-115	385.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	2|Bacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4356352_5	378806.STAUR_2935	7.929e-27	128.0	COG3468@1|root,COG3468@2|Bacteria,1Q38T@1224|Proteobacteria,438ZU@68525|delta/epsilon subdivisions,2X8SP@28221|Deltaproteobacteria,2YY9Q@29|Myxococcales	28221|Deltaproteobacteria	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4356352_0	391625.PPSIR1_33891	1.286e-186	595.0	COG0379@1|root,COG0379@2|Bacteria	2|Bacteria	H	quinolinate synthetase A activity	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0750,iAPECO1_1312.APECO1_1338,iB21_1397.B21_00692,iBWG_1329.BWG_0602,iECBD_1354.ECBD_2917,iECB_1328.ECB_00703,iECDH10B_1368.ECDH10B_0817,iECDH1ME8569_1439.ECDH1ME8569_0703,iECD_1391.ECD_00703,iECED1_1282.ECED1_0711,iECOK1_1307.ECOK1_0750,iECP_1309.ECP_0761,iECS88_1305.ECS88_0766,iECSP_1301.ECSP_0802,iECs_1301.ECs0778,iETEC_1333.ETEC_0754,iEcDH1_1363.EcDH1_2892,iEcolC_1368.EcolC_2912,iHN637.CLJU_RS12020,iJN746.PP_1231,iJO1366.b0750,iJR904.b0750,iUMN146_1321.UM146_13905,iUTI89_1310.UTI89_C0747,iY75_1357.Y75_RS03905,iZ_1308.Z0919	NadA
CMS3_k127_4356352_3	1242864.D187_003974	2.291e-43	169.0	2A9QJ@1|root,30YXQ@2|Bacteria,1PKTX@1224|Proteobacteria,4382A@68525|delta/epsilon subdivisions,2X9VJ@28221|Deltaproteobacteria,2YVEA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4356352_6	1157640.AQWO01000022_gene1662	3.211e-20	105.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
CMS3_k127_4356352_2	502025.Hoch_5811	1.072e-97	340.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_436110_11	643648.Slip_0676	7.713e-67	231.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,42KFN@68298|Syntrophomonadaceae	186801|Clostridia	G	PFAM glycosyl transferase family 35	glgP2	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS3_k127_436110_10	290397.Adeh_1135	1.059e-67	245.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_436110_6	502025.Hoch_2523	3.147e-114	409.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_2523|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_436110_8	502025.Hoch_2524	1.771e-106	385.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HtaA,TIG
CMS3_k127_436110_3	502025.Hoch_3577	9.656e-133	467.0	2AIWV@1|root,319EH@2|Bacteria,1Q2HT@1224|Proteobacteria,433TN@68525|delta/epsilon subdivisions,2X3EP@28221|Deltaproteobacteria,2YVQT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_436110_4	502025.Hoch_3578	1.279e-124	414.0	COG3005@1|root,COG3005@2|Bacteria,1QX4N@1224|Proteobacteria,43BXD@68525|delta/epsilon subdivisions,2X786@28221|Deltaproteobacteria,2Z3DX@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_436110_5	404589.Anae109_0505	8.862e-124	403.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_436110_14	502025.Hoch_4190	2.794e-43	168.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,42U9S@68525|delta/epsilon subdivisions,2WQ1X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF882)	ycbK	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
CMS3_k127_436110_7	502025.Hoch_4189	1.94e-113	372.0	COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria,2YUUD@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM asparagine synthase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
CMS3_k127_436110_23	867903.ThesuDRAFT_01269	0.000185	46.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WCCN@538999|Clostridiales incertae sedis	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_436110_21	502025.Hoch_3486	3.854e-10	72.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
CMS3_k127_436110_2	525904.Tter_0039	2.674e-152	491.0	COG2046@1|root,COG2046@2|Bacteria,2NNS5@2323|unclassified Bacteria	2|Bacteria	P	PUA-like domain	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
CMS3_k127_436110_19	502025.Hoch_4184	1.294e-19	91.0	COG0425@1|root,COG0425@2|Bacteria,1NGCU@1224|Proteobacteria,42XTE@68525|delta/epsilon subdivisions,2WSIH@28221|Deltaproteobacteria,2YW4S@29|Myxococcales	28221|Deltaproteobacteria	O	Sulfurtransferase TusA	tusA-1	-	-	-	-	-	-	-	-	-	-	-	TusA
CMS3_k127_436110_12	502025.Hoch_4180	1.998e-59	210.0	COG1310@1|root,COG1310@2|Bacteria,1NYED@1224|Proteobacteria	1224|Proteobacteria	S	Prokaryotic homologs of the JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
CMS3_k127_436110_1	502025.Hoch_4179	2.95e-153	496.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2YU2W@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
CMS3_k127_436110_16	502025.Hoch_4178	4.716e-27	118.0	COG0476@1|root,COG0476@2|Bacteria,1PDDQ@1224|Proteobacteria,435G7@68525|delta/epsilon subdivisions,2WZTP@28221|Deltaproteobacteria,2Z2QN@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
CMS3_k127_436110_20	314345.SPV1_14259	8.59e-14	74.0	COG1135@1|root,COG1135@2|Bacteria	2|Bacteria	P	methionine transport	-	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Fer4,NIL
CMS3_k127_436110_15	502025.Hoch_4177	5.048e-38	143.0	COG1977@1|root,COG1977@2|Bacteria,1N4Z0@1224|Proteobacteria,43B8K@68525|delta/epsilon subdivisions,2X6MX@28221|Deltaproteobacteria,2Z3BT@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_436110_0	314345.SPV1_14249	1.147e-161	520.0	COG0498@1|root,COG0498@2|Bacteria,1R7X1@1224|Proteobacteria	1224|Proteobacteria	E	Threonine synthase	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS3_k127_4373768_6	1107311.Q767_01620	2.034e-46	186.0	COG3291@1|root,COG3386@1|root,COG5306@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4PM1B@976|Bacteroidetes	976|Bacteroidetes	G	SPTR Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4373768_9	1081644.IMCC13023_01450	1.028e-10	73.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4FN7F@85023|Microbacteriaceae	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
CMS3_k127_4373768_10	1229780.BN381_130143	5.753e-07	52.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4373768_2	502025.Hoch_1849	1.661e-107	359.0	COG1087@1|root,COG1087@2|Bacteria,1R0N8@1224|Proteobacteria,43CYU@68525|delta/epsilon subdivisions,2X870@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_4373768_7	484019.THA_1265	3.757e-17	97.0	COG4267@1|root,COG4267@2|Bacteria,2GCMS@200918|Thermotogae	200918|Thermotogae	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
CMS3_k127_4373768_0	266117.Rxyl_2668	7.447e-110	377.0	COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,4CQCT@84995|Rubrobacteria	84995|Rubrobacteria	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4
CMS3_k127_4373768_11	279238.Saro_3035	2.852e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2K04M@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_14,TPR_16,TPR_19,TPR_8
CMS3_k127_4373768_1	266117.Rxyl_2670	2.713e-109	381.0	28KNN@1|root,2ZA6V@2|Bacteria,2I2ZK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4373768_5	1254432.SCE1572_11160	5.365e-62	244.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_4373768_4	404589.Anae109_3499	7.51e-70	261.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_4373768_8	48698.ENSPFOP00000027847	5.473e-12	79.0	KOG4297@1|root,KOG4297@2759|Eukaryota,39Z2X@33154|Opisthokonta,3BNS0@33208|Metazoa,3D1AT@33213|Bilateria,48AZT@7711|Chordata,496RT@7742|Vertebrata	33208|Metazoa	TV	carbohydrate binding	-	-	-	ko:K06563	ko04145,ko05152,ko05162,map04145,map05152,map05162	-	-	-	ko00000,ko00001,ko04090,ko04091,ko04131,ko04516	-	-	-	Lectin_C
CMS3_k127_4373768_3	1206726.BAFV01000022_gene1703	5.891e-82	283.0	COG0388@1|root,COG0388@2|Bacteria,2H9Z0@201174|Actinobacteria,4G7F7@85025|Nocardiaceae	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS3_k127_4380588_13	1121920.AUAU01000008_gene1568	3.132e-28	119.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
CMS3_k127_4380588_6	448385.sce1002	9.834e-120	397.0	COG4225@1|root,COG4225@2|Bacteria,1MU2J@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl Hydrolase Family 88	yesR	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
CMS3_k127_4380588_5	290400.Jann_3081	2.817e-153	516.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TWBA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381,ko:K21416	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_4380588_3	1229780.BN381_420004	2.975e-221	690.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,3UX28@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4380588_10	1415780.JPOG01000001_gene2510	4.681e-46	190.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1X5V2@135614|Xanthomonadales	135614|Xanthomonadales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS3_k127_4380588_15	1415780.JPOG01000001_gene2509	5.087e-14	85.0	COG0760@1|root,COG0760@2|Bacteria,1NNJD@1224|Proteobacteria,1SVGM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
CMS3_k127_4380588_1	1415780.JPOG01000001_gene2508	3.438e-239	761.0	2DBUU@1|root,2ZB7U@2|Bacteria,1R8WF@1224|Proteobacteria,1SMN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS3_k127_4380588_12	96561.Dole_2544	2.229e-28	122.0	COG1309@1|root,COG1309@2|Bacteria,1N208@1224|Proteobacteria	1224|Proteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4380588_2	1254432.SCE1572_51745	3.138e-222	735.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4380588_14	180281.CPCC7001_2168	1.099e-26	125.0	COG2931@1|root,COG2931@2|Bacteria,1G2GC@1117|Cyanobacteria	1117|Cyanobacteria	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
CMS3_k127_4380588_17	869210.Marky_0049	1.701e-06	63.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,1WISP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_2,PQQ_3,Pkinase
CMS3_k127_4380588_4	768710.DesyoDRAFT_1775	4.772e-207	657.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4380588_8	502025.Hoch_6429	6.615e-100	334.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,42YFC@68525|delta/epsilon subdivisions,2WU03@28221|Deltaproteobacteria,2YUBP@29|Myxococcales	28221|Deltaproteobacteria	I	desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_4380588_7	1210884.HG799463_gene9741	4.281e-104	371.0	COG3852@1|root,COG3852@2|Bacteria,2J4Y6@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
CMS3_k127_4380588_11	502025.Hoch_4439	3.612e-30	132.0	2BH8Z@1|root,32BAE@2|Bacteria,1PY0R@1224|Proteobacteria,43E00@68525|delta/epsilon subdivisions,2WZB5@28221|Deltaproteobacteria,2Z1RC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4401153_0	502025.Hoch_6339	1.281e-168	537.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_4401153_1	502025.Hoch_6340	5.408e-142	458.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42PK4@68525|delta/epsilon subdivisions,2WM1G@28221|Deltaproteobacteria,2YUAW@29|Myxococcales	28221|Deltaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS3_k127_4414800_6	502025.Hoch_2096	7.66e-133	434.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUWW@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4414800_14	502025.Hoch_2095	2.054e-50	202.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yqfZ	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_4414800_1	502025.Hoch_0087	6.368e-187	606.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4414800_16	378806.STAUR_4787	1.017e-45	190.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,439KT@68525|delta/epsilon subdivisions,2X4XM@28221|Deltaproteobacteria,2YZT0@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_4414800_8	290397.Adeh_1711	1.321e-95	334.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4414800_21	1232410.KI421416_gene2645	1.157e-11	78.0	2EE6A@1|root,3380W@2|Bacteria,1NCBW@1224|Proteobacteria,42V9R@68525|delta/epsilon subdivisions,2WSI3@28221|Deltaproteobacteria,43VQV@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4414800_5	224324.aq_2109	1.546e-136	441.0	COG0113@1|root,COG0113@2|Bacteria,2G3MJ@200783|Aquificae	200783|Aquificae	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS3_k127_4414800_3	502025.Hoch_3452	1.172e-155	507.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2YUYH@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CMS3_k127_4414800_17	502025.Hoch_3244	6.208e-45	170.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,42VH9@68525|delta/epsilon subdivisions,2WT3R@28221|Deltaproteobacteria,2YVNR@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS3_k127_4414800_15	502025.Hoch_0282	3.311e-48	181.0	2CIY5@1|root,2ZET1@2|Bacteria,1P8MM@1224|Proteobacteria,4330I@68525|delta/epsilon subdivisions,2WXKY@28221|Deltaproteobacteria,2YW19@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4414800_0	502025.Hoch_1965	1.076e-232	737.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WV45@28221|Deltaproteobacteria,2YZDV@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_4414800_23	1192034.CAP_4284	0.0005274	48.0	COG0810@1|root,COG0810@2|Bacteria,1PER0@1224|Proteobacteria,42SI5@68525|delta/epsilon subdivisions,2WZ7N@28221|Deltaproteobacteria,2Z1I6@29|Myxococcales	28221|Deltaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB2	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_4414800_13	1192034.CAP_1513	2.432e-51	210.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2Z01G@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
CMS3_k127_4414800_18	1192034.CAP_6991	2.26e-34	147.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_4414800_20	1304885.AUEY01000025_gene2741	9.079e-12	79.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,42N9J@68525|delta/epsilon subdivisions,2WK7H@28221|Deltaproteobacteria,2MKSB@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Outer membrane protein transport protein (OMPP1 FadL TodX)	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_4414800_22	7370.XP_005182163.1	3.591e-08	67.0	COG4886@1|root,KOG1217@1|root,KOG3594@1|root,KOG1217@2759|Eukaryota,KOG1219@2759|Eukaryota,KOG4237@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera	33208|Metazoa	T	Calcium ion binding	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
CMS3_k127_4414800_7	502025.Hoch_1964	3.264e-117	390.0	2BKCR@1|root,32ETA@2|Bacteria,1RJ21@1224|Proteobacteria,430EX@68525|delta/epsilon subdivisions,2WVVF@28221|Deltaproteobacteria,2YUQK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4414800_2	502025.Hoch_1963	2.19e-168	561.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2WM5N@28221|Deltaproteobacteria,2Z33T@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_4414800_4	502025.Hoch_0279	2.551e-138	462.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUMV@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4428817_0	502025.Hoch_3337	0.0	1454.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YUJ6@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_4428817_12	1144275.COCOR_07398	4.681e-08	63.0	COG0791@1|root,COG0791@2|Bacteria,1P6W3@1224|Proteobacteria,42SV7@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,NLPC_P60
CMS3_k127_4428817_5	502025.Hoch_3540	4.922e-99	338.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,2Z219@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS3_k127_4428817_2	502025.Hoch_3544	1.684e-143	464.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,2YUTU@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS3_k127_4428817_4	502025.Hoch_4797	2.807e-114	414.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1MWVZ@1224|Proteobacteria,438G1@68525|delta/epsilon subdivisions,2X3QZ@28221|Deltaproteobacteria,2YWVV@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
CMS3_k127_4428817_7	502025.Hoch_3545	1.522e-66	235.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2YVFW@29|Myxococcales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS3_k127_4428817_1	886293.Sinac_1156	1.41e-268	879.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4428817_3	1254432.SCE1572_52185	3.536e-130	439.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
CMS3_k127_4428817_9	1254432.SCE1572_15140	8.584e-13	81.0	28V7D@1|root,2ZHAI@2|Bacteria,1RA29@1224|Proteobacteria,42R9H@68525|delta/epsilon subdivisions,2WN1D@28221|Deltaproteobacteria,2Z26N@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS3_k127_4428817_10	1120968.AUBX01000016_gene1697	2.308e-10	74.0	COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia	976|Bacteroidetes	N	ABC transporter substrate-binding component GldG	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_4428817_8	1047013.AQSP01000113_gene744	1.236e-44	183.0	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	gldF	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
CMS3_k127_4428817_6	518766.Rmar_1770	3.606e-97	327.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1FJR1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ABC transporter	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4428817_13	502025.Hoch_3546	7.956e-08	58.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2Z0ZJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_443312_11	502025.Hoch_6717	4.098e-05	46.0	2AIZE@1|root,319HE@2|Bacteria,1Q2SG@1224|Proteobacteria,438E3@68525|delta/epsilon subdivisions,2X3P8@28221|Deltaproteobacteria,2YWR0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_443312_0	502025.Hoch_3553	6.094e-149	485.0	COG2067@1|root,COG2067@2|Bacteria,1Q2WT@1224|Proteobacteria,438JN@68525|delta/epsilon subdivisions,2X3UB@28221|Deltaproteobacteria,2YX4H@29|Myxococcales	28221|Deltaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_443312_2	290397.Adeh_3473	1.402e-65	251.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,2YVAA@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
CMS3_k127_443312_4	502025.Hoch_3554	1.518e-63	227.0	COG1309@1|root,COG1309@2|Bacteria,1NDYG@1224|Proteobacteria,42WJ9@68525|delta/epsilon subdivisions,2X293@28221|Deltaproteobacteria,2YZAR@29|Myxococcales	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_5,TetR_N
CMS3_k127_443312_5	378806.STAUR_3258	2.763e-61	228.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria,2YYGP@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_443312_6	502025.Hoch_3555	1.679e-53	199.0	COG0121@1|root,COG0121@2|Bacteria,1PDCQ@1224|Proteobacteria,4390T@68525|delta/epsilon subdivisions,2X45Y@28221|Deltaproteobacteria,2YYBQ@29|Myxococcales	28221|Deltaproteobacteria	S	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
CMS3_k127_443312_1	502025.Hoch_3556	2.541e-81	280.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2WPBS@28221|Deltaproteobacteria,2Z198@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	agmH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_443312_3	502025.Hoch_3557	1.741e-65	233.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_3557|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_443312_9	502025.Hoch_3558	7.615e-15	85.0	COG1426@1|root,COG1426@2|Bacteria,1NIQS@1224|Proteobacteria,4387Z@68525|delta/epsilon subdivisions,2X3HR@28221|Deltaproteobacteria,2YW5H@29|Myxococcales	28221|Deltaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
CMS3_k127_443312_7	502025.Hoch_3559	2.254e-51	203.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2YVXU@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS3_k127_443312_10	448385.sce2826	9.544e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1R0CA@1224|Proteobacteria,43EDM@68525|delta/epsilon subdivisions,2X82F@28221|Deltaproteobacteria,2Z26J@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_443312_12	176275.XP_008598657.1	8.946e-05	54.0	COG5068@1|root,KOG0014@2759|Eukaryota,38EKQ@33154|Opisthokonta,3NUMI@4751|Fungi,3QQXW@4890|Ascomycota,215I6@147550|Sordariomycetes,3TH54@5125|Hypocreales	4751|Fungi	K	Transcription factor	RLM1	GO:0000981,GO:0000982,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006355,GO:0006357,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008150,GO:0008301,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0036003,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0043618,GO:0043620,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0061392,GO:0061393,GO:0065007,GO:0071214,GO:0071470,GO:0080090,GO:0097159,GO:0104004,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K09265,ko:K19807	ko04011,map04011	-	-	-	ko00000,ko00001,ko03000	-	-	-	SRF-TF
CMS3_k127_4449829_5	502025.Hoch_0507	4.643e-39	162.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS3_k127_4449829_0	502025.Hoch_0506	4.972e-135	438.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,2Z35M@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
CMS3_k127_4449829_6	502025.Hoch_0505	1.529e-35	147.0	COG1047@1|root,COG1047@2|Bacteria	2|Bacteria	O	modulation by symbiont of host adenylate cyclase-mediated signal transduction	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS3_k127_4449829_1	670487.Ocepr_0158	5.889e-88	311.0	COG0154@1|root,COG0154@2|Bacteria,1WIG3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CMS3_k127_4449829_9	1144275.COCOR_01215	1.051e-08	69.0	COG0810@1|root,COG1716@1|root,COG0810@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	bscD	-	-	ko:K03220,ko:K03832	-	M00332	-	-	ko00000,ko00002,ko02000,ko02044	2.C.1.1,3.A.6.1	-	-	FHA,TonB_2,TonB_C
CMS3_k127_4449829_3	502025.Hoch_5255	4.996e-83	298.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,43B0B@68525|delta/epsilon subdivisions,2X6EF@28221|Deltaproteobacteria,2Z3AR@29|Myxococcales	28221|Deltaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_4449829_4	1306990.BARG01000110_gene9859	1.119e-80	291.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_4449829_8	237368.SCABRO_02648	4.335e-09	68.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	spsI	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0016780	2.7.7.74,2.7.8.34	ko:K07281,ko:K07291	ko00562,map00562	-	R09669,R09670	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,NTP_transf_3
CMS3_k127_4449829_2	1150600.ADIARSV_3951	2.333e-86	308.0	COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,1IP24@117747|Sphingobacteriia	976|Bacteroidetes	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
CMS3_k127_4455514_15	945713.IALB_2307	5.094e-28	115.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2,Peptidase_C70,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_4455514_4	945713.IALB_2306	8.279e-71	256.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_4455514_14	1385518.N798_05590	9.755e-30	138.0	COG1502@1|root,COG1502@2|Bacteria,2GN2V@201174|Actinobacteria,4FE9K@85021|Intrasporangiaceae	201174|Actinobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
CMS3_k127_4455514_9	330214.NIDE0195	1.926e-43	176.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_4455514_13	502025.Hoch_3438	1.939e-35	137.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WT56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_4455514_17	1200557.JHWV01000017_gene820	1.221e-13	78.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,4H4IK@909932|Negativicutes	909932|Negativicutes	K	PFAM Transcription factor CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
CMS3_k127_4455514_1	502025.Hoch_2755	1.38e-175	570.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2YTW6@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS3_k127_4455514_5	391625.PPSIR1_16510	2.898e-69	243.0	COG0823@1|root,COG3266@1|root,COG0823@2|Bacteria,COG3266@2|Bacteria,1RI0N@1224|Proteobacteria,43CN9@68525|delta/epsilon subdivisions,2X7VJ@28221|Deltaproteobacteria,2Z048@29|Myxococcales	28221|Deltaproteobacteria	U	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
CMS3_k127_4455514_2	3218.PP1S2_113V6.2	5.657e-151	500.0	COG0626@1|root,KOG0053@2759|Eukaryota,37RGY@33090|Viridiplantae,3GB43@35493|Streptophyta	35493|Streptophyta	E	methionine	MGL	GO:0000096,GO:0000097,GO:0000098,GO:0001101,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0006950,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009067,GO:0009068,GO:0009069,GO:0009070,GO:0009086,GO:0009087,GO:0009092,GO:0009267,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009970,GO:0009987,GO:0009991,GO:0010035,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0018826,GO:0019343,GO:0019344,GO:0019346,GO:0019458,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0042221,GO:0042594,GO:0042631,GO:0043167,GO:0043168,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0048037,GO:0050662,GO:0050667,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0065003,GO:0070279,GO:0070887,GO:0071214,GO:0071229,GO:0071265,GO:0071266,GO:0071462,GO:0071496,GO:0071704,GO:0071840,GO:0097159,GO:0104004,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901700,GO:1901701	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_4455514_12	1079986.JH164852_gene200	7.464e-37	151.0	COG0583@1|root,COG0583@2|Bacteria,2ICPR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_4455514_0	765912.Thimo_2452	0.0	1686.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales	135613|Chromatiales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CMS3_k127_4455514_3	622637.KE124774_gene1484	5.268e-101	350.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,36XCM@31993|Methylocystaceae	28211|Alphaproteobacteria	V	ABC transporter transmembrane region	exsA	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4455514_19	595536.ADVE02000001_gene1442	1.386e-08	68.0	29XVG@1|root,30JMR@2|Bacteria,1Q3EW@1224|Proteobacteria,2VC3U@28211|Alphaproteobacteria,37154@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
CMS3_k127_4455514_18	338966.Ppro_0048	1.587e-09	68.0	2DRDY@1|root,33BC0@2|Bacteria,1NHDE@1224|Proteobacteria,42WZU@68525|delta/epsilon subdivisions,2WXJP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
CMS3_k127_4455514_6	1487953.JMKF01000041_gene3159	3.421e-61	237.0	COG0367@1|root,COG0367@2|Bacteria,1G3S7@1117|Cyanobacteria,1H8UK@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_4455514_20	269796.Rru_A1280	1.917e-06	61.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,2UFMX@28211|Alphaproteobacteria,2JZUA@204441|Rhodospirillales	204441|Rhodospirillales	T	HPr Serine kinase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4455514_8	395961.Cyan7425_1024	4.995e-50	196.0	COG4076@1|root,COG4076@2|Bacteria,1G4RK@1117|Cyanobacteria	1117|Cyanobacteria	J	PRMT5 arginine-N-methyltransferase	-	-	2.1.1.319	ko:K11434	ko04068,ko04922,map04068,map04922	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko00001,ko01000,ko03036	-	-	-	PRMT5_C,PrmA
CMS3_k127_4455514_7	4558.Sb10g028960.1	4.699e-57	215.0	COG0661@1|root,KOG1235@2759|Eukaryota,37N5M@33090|Viridiplantae,3GF6V@35493|Streptophyta,3KKZJ@4447|Liliopsida,3I4GY@38820|Poales	35493|Streptophyta	S	Beta-lactamase	-	-	-	ko:K08869	-	-	-	-	ko00000,ko01001	-	-	-	ABC1,Beta-lactamase,WaaY
CMS3_k127_4455514_16	1298863.AUEP01000001_gene972	9.979e-15	83.0	COG4529@1|root,COG4529@2|Bacteria,2GNX3@201174|Actinobacteria,4DN0U@85009|Propionibacteriales	201174|Actinobacteria	S	FAD-NAD(P)-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_9
CMS3_k127_447691_18	502025.Hoch_2556	1.791e-80	277.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria,2YUYK@29|Myxococcales	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
CMS3_k127_447691_15	502025.Hoch_2558	2.668e-98	339.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
CMS3_k127_447691_13	502025.Hoch_2559	6.456e-115	380.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WJV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_447691_10	502025.Hoch_2560	3.32e-124	437.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2YV07@29|Myxococcales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_447691_19	269799.Gmet_0193	1.269e-78	269.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria,43U0V@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS3_k127_447691_9	502025.Hoch_2562	1.7e-134	452.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2YUS7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS3_k127_447691_3	502025.Hoch_2563	5.692e-166	544.0	COG2203@1|root,COG5000@1|root,COG2203@2|Bacteria,COG5000@2|Bacteria,1RGKE@1224|Proteobacteria,43BX6@68525|delta/epsilon subdivisions,2WNRP@28221|Deltaproteobacteria,2YTVD@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HisKA,PAS,PAS_4
CMS3_k127_447691_4	502025.Hoch_2564	2.807e-148	493.0	COG4191@1|root,COG4191@2|Bacteria,1R9SH@1224|Proteobacteria,42QAE@68525|delta/epsilon subdivisions,2WM61@28221|Deltaproteobacteria,2Z2WP@29|Myxococcales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,dCache_1
CMS3_k127_447691_36	391625.PPSIR1_16740	8.56e-33	149.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_447691_14	502025.Hoch_5811	1.227e-109	378.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_447691_43	378806.STAUR_3148	1.822e-11	78.0	2AJ2K@1|root,319KX@2|Bacteria,1Q33W@1224|Proteobacteria,438UP@68525|delta/epsilon subdivisions,2X9IR@28221|Deltaproteobacteria,2YXTT@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_447691_26	161156.JQKW01000006_gene1373	8.997e-60	214.0	COG1136@1|root,COG1136@2|Bacteria,2GHBG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_447691_5	502025.Hoch_3460	1.308e-147	494.0	COG0577@1|root,COG0577@2|Bacteria,1QXV8@1224|Proteobacteria,43C7Z@68525|delta/epsilon subdivisions,2X7IB@28221|Deltaproteobacteria,2YUZK@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CMS3_k127_447691_28	1120985.AUMI01000004_gene1350	2.587e-50	202.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H40T@909932|Negativicutes	909932|Negativicutes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_447691_8	378806.STAUR_6358	5.079e-142	486.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2WM5N@28221|Deltaproteobacteria,2Z33T@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_447691_46	710111.FraQA3DRAFT_2501	3.111e-05	55.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4EU3X@85013|Frankiales	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_447691_25	1068980.ARVW01000001_gene2968	2.275e-60	222.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	cpsL	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,ATPgrasp_Ter
CMS3_k127_447691_42	797210.Halxa_0792	1.436e-12	78.0	COG0546@1|root,arCOG02296@2157|Archaea,2XXY2@28890|Euryarchaeota,23W42@183963|Halobacteria	183963|Halobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_447691_38	370438.PTH_1466	4.267e-27	126.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,267CB@186807|Peptococcaceae	186801|Clostridia	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_447691_34	502025.Hoch_4155	3.043e-37	148.0	COG4969@1|root,COG4969@2|Bacteria,1R0CQ@1224|Proteobacteria,43CV8@68525|delta/epsilon subdivisions,2X835@28221|Deltaproteobacteria,2Z3JW@29|Myxococcales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
CMS3_k127_447691_37	502025.Hoch_4155	3.107e-28	124.0	COG4969@1|root,COG4969@2|Bacteria,1R0CQ@1224|Proteobacteria,43CV8@68525|delta/epsilon subdivisions,2X835@28221|Deltaproteobacteria,2Z3JW@29|Myxococcales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
CMS3_k127_447691_45	767434.Fraau_2187	9.169e-06	55.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1X8A4@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
CMS3_k127_447691_1	502025.Hoch_4153	4.537e-198	629.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJ9@29|Myxococcales	28221|Deltaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_447691_16	502025.Hoch_4152	2.991e-93	332.0	COG0500@1|root,COG2226@2|Bacteria,1RASQ@1224|Proteobacteria,42QTY@68525|delta/epsilon subdivisions,2WMN2@28221|Deltaproteobacteria,2YWX8@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_447691_32	502025.Hoch_2507	1.457e-38	165.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_447691_12	502025.Hoch_4151	4.533e-122	406.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,2YUUH@29|Myxococcales	28221|Deltaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2
CMS3_k127_447691_39	243231.GSU2508	1.002e-18	100.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_447691_29	391625.PPSIR1_08866	1.008e-48	193.0	2A4SI@1|root,30TDY@2|Bacteria,1PD6V@1224|Proteobacteria,435EQ@68525|delta/epsilon subdivisions,2X98Q@28221|Deltaproteobacteria,2Z2N2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_447691_30	215803.DB30_7241	2.984e-42	172.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,4372N@68525|delta/epsilon subdivisions,2X1UJ@28221|Deltaproteobacteria,2Z0EY@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_447691_2	391625.PPSIR1_12878	2.435e-190	609.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2YYFS@29|Myxococcales	28221|Deltaproteobacteria	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS3_k127_447691_48	1250278.JQNQ01000001_gene2748	0.0007702	51.0	COG1266@1|root,COG1266@2|Bacteria,4NHRW@976|Bacteroidetes,1I1CE@117743|Flavobacteriia	976|Bacteroidetes	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_447691_27	234267.Acid_7187	1.744e-55	218.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_447691_33	502025.Hoch_4892	1.129e-37	148.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2WNWA@28221|Deltaproteobacteria,2YW6N@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_447691_47	502025.Hoch_2523	0.0002058	53.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_2523|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_447691_22	391625.PPSIR1_30489	1.808e-66	229.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,42VSH@68525|delta/epsilon subdivisions,2WRFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS3_k127_447691_17	1519464.HY22_05280	4.059e-92	316.0	COG1744@1|root,COG1744@2|Bacteria,1FDN9@1090|Chlorobi	1090|Chlorobi	S	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
CMS3_k127_447691_7	1379270.AUXF01000002_gene1764	1.565e-142	486.0	COG3845@1|root,COG3845@2|Bacteria,1ZSUG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
CMS3_k127_447691_11	502025.Hoch_6737	1.424e-123	418.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42RQG@68525|delta/epsilon subdivisions,2WNDT@28221|Deltaproteobacteria,2YZU8@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_447691_20	861299.J421_2315	1.027e-74	276.0	COG1079@1|root,COG1079@2|Bacteria,1ZTFZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_447691_24	1192034.CAP_7281	4.355e-62	226.0	COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,432YH@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyl hydrolases family 25	yegX	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
CMS3_k127_447691_6	555088.DealDRAFT_2903	7.28e-143	476.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,42K30@68298|Syntrophomonadaceae	186801|Clostridia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS3_k127_447691_35	330214.NIDE4322	1.025e-34	144.0	COG0744@1|root,COG0744@2|Bacteria,3J127@40117|Nitrospirae	40117|Nitrospirae	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS3_k127_447691_23	502025.Hoch_3476	1.144e-62	228.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_447691_0	1144275.COCOR_03319	5.7e-227	713.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2YXPT@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS3_k127_4482957_1	1396141.BATP01000061_gene4490	1.612e-98	338.0	COG2805@1|root,COG2805@2|Bacteria,46UF2@74201|Verrucomicrobia,2ITJW@203494|Verrucomicrobiae	74201|Verrucomicrobia	NU	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
CMS3_k127_4482957_0	1380394.JADL01000001_gene2668	2.801e-114	378.0	COG0662@1|root,COG0662@2|Bacteria,1NX8W@1224|Proteobacteria,2TY4P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_4482957_2	1220534.B655_1034	1.943e-65	251.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4507905_10	502025.Hoch_4074	2.932e-77	273.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4507905_21	1227349.C170_15350	2.397e-26	116.0	COG1670@1|root,COG1670@2|Bacteria,1V54D@1239|Firmicutes,4HIQW@91061|Bacilli,26Y91@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_4507905_16	1048339.KB913029_gene933	6.744e-49	181.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4ET6A@85013|Frankiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_4507905_22	502025.Hoch_6490	7.997e-22	109.0	2C9M1@1|root,2ZSUM@2|Bacteria,1R0NN@1224|Proteobacteria,43CZC@68525|delta/epsilon subdivisions,2X87J@28221|Deltaproteobacteria,2Z3MM@29|Myxococcales	502025.Hoch_6490|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4507905_15	393595.ABO_1568	1.921e-58	213.0	COG0625@1|root,COG0625@2|Bacteria,1R7YC@1224|Proteobacteria,1S06X@1236|Gammaproteobacteria,1XPJ2@135619|Oceanospirillales	135619|Oceanospirillales	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
CMS3_k127_4507905_19	391625.PPSIR1_41179	1.2e-30	132.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4507905_18	1313421.JHBV01000043_gene3191	1.34e-31	139.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_4507905_5	1403819.BATR01000162_gene5394	9.232e-129	421.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_4507905_9	450851.PHZ_c1272	7.259e-82	292.0	COG3000@1|root,COG3000@2|Bacteria,1PRYJ@1224|Proteobacteria,2V466@28211|Alphaproteobacteria,2KH00@204458|Caulobacterales	204458|Caulobacterales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_4507905_3	1254432.SCE1572_00985	1.342e-155	531.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
CMS3_k127_4507905_0	926550.CLDAP_00560	0.0	1881.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
CMS3_k127_4507905_2	1254432.SCE1572_18340	2.857e-171	546.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_4507905_11	1278073.MYSTI_07489	1.405e-67	249.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria,42S3P@68525|delta/epsilon subdivisions,2WNCE@28221|Deltaproteobacteria,2YUQB@29|Myxococcales	28221|Deltaproteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
CMS3_k127_4507905_8	1198232.CYCME_2222	1.045e-102	346.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,460KK@72273|Thiotrichales	72273|Thiotrichales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4507905_7	502025.Hoch_5360	2.901e-103	345.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,42QST@68525|delta/epsilon subdivisions,2WMN8@28221|Deltaproteobacteria,2YZ74@29|Myxococcales	28221|Deltaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CMS3_k127_4507905_6	743525.TSC_c19730	2.843e-119	423.0	COG0604@1|root,COG0604@2|Bacteria,1WI1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_4507905_23	502025.Hoch_6038	1.731e-21	102.0	2EQUD@1|root,33IE5@2|Bacteria,1N9A0@1224|Proteobacteria,43CZ1@68525|delta/epsilon subdivisions,2X878@28221|Deltaproteobacteria,2Z3MG@29|Myxococcales	1224|Proteobacteria	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS3_k127_4507905_26	215803.DB30_2423	1.486e-06	61.0	COG1404@1|root,COG3291@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YZ9E@29|Myxococcales	28221|Deltaproteobacteria	OQ	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
CMS3_k127_4507905_13	448385.sce4979	1.819e-60	215.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,1N34Y@1224|Proteobacteria,42TV3@68525|delta/epsilon subdivisions,2WQ5Z@28221|Deltaproteobacteria,2YUQ5@29|Myxococcales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_31
CMS3_k127_4507905_24	1296415.JACC01000009_gene2007	1.001e-20	102.0	COG0697@1|root,COG0697@2|Bacteria,4P10M@976|Bacteroidetes,1IGAV@117743|Flavobacteriia,2YJ46@290174|Aquimarina	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_4507905_14	1173026.Glo7428_2144	2.96e-59	230.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS3_k127_4507905_12	644968.DFW101_2140	5.642e-64	236.0	COG2173@1|root,COG2173@2|Bacteria,1N3QY@1224|Proteobacteria,42TQ8@68525|delta/epsilon subdivisions,2WNK8@28221|Deltaproteobacteria,2M9YV@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
CMS3_k127_4507905_17	59374.Fisuc_2480	1.92e-35	145.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K07110,ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,DUF4423,HTH_3,HTH_31,Peptidase_M78
CMS3_k127_4507905_27	264462.Bd3719	1.81e-05	55.0	29W44@1|root,30HNZ@2|Bacteria,1P948@1224|Proteobacteria	264462.Bd3719|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4507905_4	269799.Gmet_1647	2.352e-151	496.0	COG1858@1|root,COG1858@2|Bacteria,1QW34@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4507905_1	1248916.ANFY01000003_gene685	1.042e-210	665.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4507905_20	502025.Hoch_5231	1.024e-28	117.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YYE4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4517244_5	28444.JODQ01000004_gene6419	3.881e-43	182.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Metallophos
CMS3_k127_4517244_6	1463917.JODC01000034_gene8353	9.638e-09	66.0	COG1520@1|root,COG1520@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
CMS3_k127_4517244_4	502025.Hoch_5141	1.463e-89	301.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2YVHB@29|Myxococcales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS3_k127_4517244_1	502025.Hoch_5140	2.508e-128	439.0	2A42Z@1|root,32C6D@2|Bacteria,1QAC4@1224|Proteobacteria,434Z4@68525|delta/epsilon subdivisions,2X93A@28221|Deltaproteobacteria,2Z1P0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4517244_0	502025.Hoch_6586	3.347e-205	661.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2Z315@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
CMS3_k127_4517244_2	502025.Hoch_6585	2.935e-122	407.0	COG1721@1|root,COG1721@2|Bacteria,1N8IQ@1224|Proteobacteria,42S2K@68525|delta/epsilon subdivisions,2WNA2@28221|Deltaproteobacteria,2YVGE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4517244_3	502025.Hoch_6584	1.75e-116	379.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WIYY@28221|Deltaproteobacteria,2YWP3@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4520529_3	640511.BC1002_5570	7.35e-69	256.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
CMS3_k127_4520529_8	502025.Hoch_1817	5.48e-08	64.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4520529_6	1307759.JOMJ01000003_gene1541	8.265e-16	89.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	fleS	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Pkinase,Response_reg
CMS3_k127_4520529_7	1123229.AUBC01000014_gene3005	5.354e-09	66.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria,3JTG9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4520529_4	1144312.PMI09_04874	1.048e-37	145.0	COG2044@1|root,COG2044@2|Bacteria,1RGAZ@1224|Proteobacteria,2UBFX@28211|Alphaproteobacteria,4BEWP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_4520529_0	314262.MED193_14497	8.496e-140	450.0	COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,2TU6R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhaA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4520529_5	314230.DSM3645_08992	8.005e-32	145.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_4520529_2	1254432.SCE1572_17845	7.418e-88	310.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,430JB@68525|delta/epsilon subdivisions,2WVTU@28221|Deltaproteobacteria,2YWQ0@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_4520529_1	502025.Hoch_3417	3.123e-90	302.0	COG4292@1|root,COG4292@2|Bacteria,1QWAK@1224|Proteobacteria,42ZNP@68525|delta/epsilon subdivisions,2WUUY@28221|Deltaproteobacteria,2Z1WT@29|Myxococcales	28221|Deltaproteobacteria	S	K channel, inward rectifier	-	-	-	-	-	-	-	-	-	-	-	-	IRK,LtrA
CMS3_k127_4539226_3	502025.Hoch_2143	1.569e-23	106.0	2A4WF@1|root,30TI4@2|Bacteria,1PDD5@1224|Proteobacteria,435F2@68525|delta/epsilon subdivisions,2WZSM@28221|Deltaproteobacteria,2Z2NW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4539226_7	502025.Hoch_2366	8.924e-06	57.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4539226_2	215803.DB30_3928	1.414e-25	125.0	2C7GM@1|root,304FY@2|Bacteria,1QR31@1224|Proteobacteria,43DY7@68525|delta/epsilon subdivisions,2WZ6D@28221|Deltaproteobacteria,2Z1F6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4539226_1	997296.PB1_08577	2.829e-31	140.0	COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4HDPI@91061|Bacilli,1ZS8C@1386|Bacillus	91061|Bacilli	G	COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NAGPA,Pur_ac_phosph_N
CMS3_k127_4539226_0	502025.Hoch_5627	9.526e-157	514.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
CMS3_k127_4539226_5	1123508.JH636439_gene352	6.457e-09	64.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	HSP70,Pkinase,TIR_2,WD40
CMS3_k127_4541475_1	1242864.D187_005635	1.165e-173	559.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2YTYA@29|Myxococcales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS3_k127_4541475_3	570967.JMLV01000002_gene1908	1.281e-121	403.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2JPEF@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS3_k127_4541475_4	502025.Hoch_4919	1.081e-51	187.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria,2Z2Z7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS3_k127_4541475_7	502025.Hoch_4920	4.403e-37	155.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Belongs to the SUA5 family	sua5	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS3_k127_4541475_2	502025.Hoch_4921	6.308e-136	444.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,2Z31V@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CMS3_k127_4541475_0	886293.Sinac_1156	5.667e-268	872.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4541475_5	215803.DB30_7594	1.021e-44	175.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
CMS3_k127_4541475_6	1476583.DEIPH_ctg012orf0056	1.281e-43	177.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM_1	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_4541475_8	749414.SBI_05223	5.381e-09	66.0	COG0789@1|root,COG0789@2|Bacteria,2I9B3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_4543494_0	502025.Hoch_4451	5.114e-119	395.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_4543494_2	502025.Hoch_4450	1.366e-81	287.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_4543494_5	264462.Bd3044	4.66e-11	65.0	COG2036@1|root,COG2036@2|Bacteria,1N3S6@1224|Proteobacteria,42UYX@68525|delta/epsilon subdivisions,2MU6K@213481|Bdellovibrionales,2WQE4@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4543494_3	502025.Hoch_4448	3.395e-37	151.0	COG0526@1|root,COG0526@2|Bacteria,1RHR7@1224|Proteobacteria,42WV1@68525|delta/epsilon subdivisions,2WSIX@28221|Deltaproteobacteria,2YVQA@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_4543494_4	502025.Hoch_4448	9.652e-35	139.0	COG0526@1|root,COG0526@2|Bacteria,1RHR7@1224|Proteobacteria,42WV1@68525|delta/epsilon subdivisions,2WSIX@28221|Deltaproteobacteria,2YVQA@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_4564675_9	1144275.COCOR_04089	1.068e-25	122.0	2BCR5@1|root,326BM@2|Bacteria,1QAS5@1224|Proteobacteria,43E3F@68525|delta/epsilon subdivisions,2WZKS@28221|Deltaproteobacteria,2Z2BX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4564675_11	448385.sce1024	4.437e-13	81.0	COG2863@1|root,COG2863@2|Bacteria,1NDS5@1224|Proteobacteria,43CTZ@68525|delta/epsilon subdivisions,2X81J@28221|Deltaproteobacteria,2YVKA@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4564675_10	65393.PCC7424_2993	2.305e-22	110.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_66,HemolysinCabind
CMS3_k127_4564675_1	502025.Hoch_1456	1.014e-108	373.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z3I1@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4564675_3	502025.Hoch_3192	5.302e-77	265.0	COG3108@1|root,COG3108@2|Bacteria,1QABK@1224|Proteobacteria,434YH@68525|delta/epsilon subdivisions,2WZ9D@28221|Deltaproteobacteria,2Z1MT@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_2
CMS3_k127_4564675_4	502025.Hoch_4494	1.923e-71	244.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2YV1R@29|Myxococcales	28221|Deltaproteobacteria	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
CMS3_k127_4564675_0	1304885.AUEY01000018_gene1102	8.465e-297	937.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MI4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS3_k127_4564675_5	502025.Hoch_4493	1.324e-58	208.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,2YVW9@29|Myxococcales	28221|Deltaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_4564675_2	502025.Hoch_4492	6.036e-82	282.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2YVDG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_4564675_8	502025.Hoch_5446	8.674e-37	144.0	COG1366@1|root,COG1366@2|Bacteria,1NG3I@1224|Proteobacteria,42W69@68525|delta/epsilon subdivisions,2WS39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4564675_6	1192034.CAP_4226	3.992e-45	183.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Glucosaminidase,Glyco_hydro_19,PG_binding_1,SLT,TMP_2,VanY
CMS3_k127_4564675_7	477974.Daud_2033	1.378e-38	147.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26020@186807|Peptococcaceae	186801|Clostridia	EH	Anthranilate synthase component I	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
CMS3_k127_4567324_5	502025.Hoch_3372	1.272e-75	260.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2YUNH@29|Myxococcales	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS3_k127_4567324_1	880073.Calab_2574	0.0	1086.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_4567324_4	502025.Hoch_3374	1.283e-97	336.0	COG3391@1|root,COG3391@2|Bacteria,1QAIP@1224|Proteobacteria,43545@68525|delta/epsilon subdivisions,2WZF8@28221|Deltaproteobacteria,2Z20B@29|Myxococcales	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4567324_2	502025.Hoch_3375	8.84e-155	537.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Laminin_G_3,VCBS
CMS3_k127_4567324_6	502025.Hoch_3376	1.362e-52	196.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,42X25@68525|delta/epsilon subdivisions,2WSPI@28221|Deltaproteobacteria,2Z3GD@29|Myxococcales	28221|Deltaproteobacteria	D	Sporulation related domain	agmI	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS3_k127_4567324_0	502025.Hoch_3422	0.0	1117.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,2YTZJ@29|Myxococcales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS3_k127_4567324_3	502025.Hoch_3711	4.472e-129	424.0	COG0823@1|root,COG0823@2|Bacteria,1PFBB@1224|Proteobacteria,432XJ@68525|delta/epsilon subdivisions,2WXKI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4580090_0	502025.Hoch_2751	4.15e-274	851.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2YTT7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
CMS3_k127_4580090_7	1380394.JADL01000003_gene4842	3.833e-133	436.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,2TUBT@28211|Alphaproteobacteria,2JV5N@204441|Rhodospirillales	204441|Rhodospirillales	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4580090_2	1125863.JAFN01000001_gene1218	5.415e-266	851.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_4580090_11	1125863.JAFN01000001_gene1219	2.923e-49	192.0	COG2080@1|root,COG2080@2|Bacteria,1Q9C0@1224|Proteobacteria,42TB7@68525|delta/epsilon subdivisions,2WPGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_4580090_10	768672.Desfe_0769	1.575e-56	207.0	COG1319@1|root,arCOG01926@2157|Archaea,2XQPN@28889|Crenarchaeota	28889|Crenarchaeota	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_4580090_8	76114.ebA2066	1.432e-119	421.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_4580090_4	1244869.H261_14175	6.673e-224	711.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	-	-	-	-	-	-	-	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS3_k127_4580090_13	292459.STH1187	4.218e-33	146.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia	186801|Clostridia	I	TIGRFAM Methylmalonyl-CoA mutase, C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CMS3_k127_4580090_9	1244869.H261_12221	2.447e-118	415.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JPPM@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4580090_1	316055.RPE_3216	6.402e-272	853.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,3JRW4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS3_k127_4580090_3	1125863.JAFN01000001_gene1223	5.187e-255	820.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS3_k127_4580090_14	335543.Sfum_4076	2.78e-26	128.0	COG1014@1|root,COG1014@2|Bacteria,1RBZA@1224|Proteobacteria,42QT3@68525|delta/epsilon subdivisions,2X6H9@28221|Deltaproteobacteria,2MS04@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
CMS3_k127_4580090_6	1125863.JAFN01000001_gene1239	7.563e-145	501.0	COG0493@1|root,COG4231@1|root,COG0493@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WKYE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-2	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
CMS3_k127_4580090_15	589924.Ferp_2325	1.665e-18	91.0	arCOG10401@1|root,arCOG10401@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4580090_5	502025.Hoch_4573	1.98e-187	642.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
CMS3_k127_4580090_16	483219.LILAB_10390	6.187e-09	69.0	2A4RA@1|root,30TCP@2|Bacteria,1PD5N@1224|Proteobacteria,438SW@68525|delta/epsilon subdivisions,2X9CX@28221|Deltaproteobacteria,2YXPJ@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_4580090_12	448385.sce2440	9.816e-44	183.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,He_PIG,HemolysinCabind
CMS3_k127_4593879_4	502025.Hoch_5432	1.415e-53	201.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,42U6P@68525|delta/epsilon subdivisions,2WQ00@28221|Deltaproteobacteria,2YVG1@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS3_k127_4593879_1	502025.Hoch_5435	1.515e-96	320.0	COG1708@1|root,COG1708@2|Bacteria,1NKZT@1224|Proteobacteria,430VC@68525|delta/epsilon subdivisions,2WVUS@28221|Deltaproteobacteria,2Z164@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
CMS3_k127_4593879_11	273116.14324701	4.185e-06	57.0	COG0484@1|root,arCOG02846@2157|Archaea,2XV5D@28890|Euryarchaeota,241ME@183967|Thermoplasmata	183967|Thermoplasmata	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_4593879_8	502025.Hoch_5436	4.647e-24	103.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,2YW65@29|Myxococcales	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS3_k127_4593879_3	1254432.SCE1572_48960	1.217e-53	201.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2Z01G@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
CMS3_k127_4593879_10	269798.CHU_1238	1.284e-07	64.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Dockerin_1,Malectin
CMS3_k127_4593879_9	1121346.KB899808_gene3499	7.766e-18	90.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,4HHB5@91061|Bacilli,26WW1@186822|Paenibacillaceae	91061|Bacilli	NT	Chemotaxis protein CheW	cheW	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS3_k127_4593879_5	517418.Ctha_2353	3.38e-44	182.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	mcp64H-2	-	-	ko:K02660,ko:K03406,ko:K11525	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_3
CMS3_k127_4593879_6	1470591.BW41_01815	1.92e-40	165.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2U1VY@28211|Alphaproteobacteria,2K2T1@204457|Sphingomonadales	204457|Sphingomonadales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS3_k127_4593879_0	639282.DEFDS_0424	2.677e-125	434.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,2GEP8@200930|Deferribacteres	200930|Deferribacteres	T	two-component system, chemotaxis family, sensor kinase CheA with response regulator domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
CMS3_k127_4593879_2	156889.Mmc1_1528	3.14e-60	222.0	COG0745@1|root,COG2114@1|root,COG2201@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cyaD	-	2.1.1.80,3.1.1.61,3.5.1.44,4.6.1.1	ko:K00575,ko:K01768,ko:K03412,ko:K03413,ko:K07719,ko:K13924	ko00230,ko02020,ko02025,ko02030,ko04113,ko04213,map00230,map02020,map02025,map02030,map04113,map04213	M00506,M00518,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,FHA,Fer2,GAF,GAF_2,Guanylate_cyc,Pkinase,Response_reg
CMS3_k127_4613112_2	502025.Hoch_6035	8.102e-56	203.0	COG1266@1|root,COG1266@2|Bacteria,1PUV4@1224|Proteobacteria,434WT@68525|delta/epsilon subdivisions,2WZ7S@28221|Deltaproteobacteria,2Z1ID@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_4613112_12	1173020.Cha6605_0233	4.282e-15	81.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_4613112_8	1121939.L861_13770	2.472e-26	113.0	COG1017@1|root,COG1017@2|Bacteria,1RI9P@1224|Proteobacteria,1S7H7@1236|Gammaproteobacteria,1XMN2@135619|Oceanospirillales	135619|Oceanospirillales	C	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4613112_11	211586.SO_1237	8.635e-16	87.0	COG0517@1|root,COG0517@2|Bacteria,1N13S@1224|Proteobacteria,1SA4N@1236|Gammaproteobacteria,2QBWX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_4613112_5	290397.Adeh_1556	1.544e-35	147.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
CMS3_k127_4613112_0	319225.Plut_0344	1.633e-70	251.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4613112_6	1278073.MYSTI_05704	1.752e-32	131.0	29Z98@1|root,30M7E@2|Bacteria,1Q42T@1224|Proteobacteria,43457@68525|delta/epsilon subdivisions,2X5AM@28221|Deltaproteobacteria,2Z0CC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4613112_14	717605.Theco_3383	1.619e-05	58.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,4HBYA@91061|Bacilli,277A8@186822|Paenibacillaceae	91061|Bacilli	G	Arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,Glyco_hydro_53,SLH
CMS3_k127_4613112_10	935836.JAEL01000034_gene4412	1.185e-19	104.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,4H9WI@91061|Bacilli,1ZE1B@1386|Bacillus	91061|Bacilli	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cu_amine_oxidN1,NAGPA,SLH
CMS3_k127_4613112_1	1122134.KB893650_gene220	7.802e-67	236.0	2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4613112_3	391625.PPSIR1_07178	9.681e-55	202.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_4613112_9	1484460.JSWG01000008_gene2047	3.009e-21	111.0	COG0457@1|root,COG3206@1|root,COG0457@2|Bacteria,COG3206@2|Bacteria,4NH33@976|Bacteroidetes,1HYMC@117743|Flavobacteriia	976|Bacteroidetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_4613112_4	1121106.JQKB01000049_gene3069	4.525e-52	192.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4613112_7	247490.KSU1_B0521	2.662e-27	125.0	COG1840@1|root,COG1840@2|Bacteria,2IXGE@203682|Planctomycetes	203682|Planctomycetes	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
CMS3_k127_4623924_7	1192034.CAP_6386	1.899e-53	203.0	COG0625@1|root,COG0625@2|Bacteria,1R7YC@1224|Proteobacteria	1224|Proteobacteria	O	COG0695 glutaredoxin and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
CMS3_k127_4623924_9	1121468.AUBR01000008_gene2057	1.109e-25	113.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,42GWU@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
CMS3_k127_4623924_4	309801.trd_A0348	4.531e-74	256.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi,27XWZ@189775|Thermomicrobia	189775|Thermomicrobia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS3_k127_4623924_10	502025.Hoch_6874	6.693e-22	112.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
CMS3_k127_4623924_2	502025.Hoch_6876	1.452e-114	377.0	COG0392@1|root,COG0392@2|Bacteria,1R4IS@1224|Proteobacteria,42WRK@68525|delta/epsilon subdivisions,2WSAB@28221|Deltaproteobacteria,2Z0VY@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS3_k127_4623924_3	502025.Hoch_6877	6.241e-110	364.0	COG0501@1|root,COG0501@2|Bacteria,1NG7Y@1224|Proteobacteria,439MR@68525|delta/epsilon subdivisions,2X4YW@28221|Deltaproteobacteria,2YZV7@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_4623924_0	502025.Hoch_6878	1.025e-240	772.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,42PVB@68525|delta/epsilon subdivisions,2WIMK@28221|Deltaproteobacteria,2YZ8C@29|Myxococcales	28221|Deltaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CMS3_k127_4623924_1	502025.Hoch_6880	4.825e-222	720.0	COG0457@1|root,COG0699@1|root,COG0457@2|Bacteria,COG0699@2|Bacteria,1NBKR@1224|Proteobacteria,42NDN@68525|delta/epsilon subdivisions,2WY2Q@28221|Deltaproteobacteria,2YW2X@29|Myxococcales	28221|Deltaproteobacteria	S	50S ribosome-binding GTPase	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MMR_HSR1
CMS3_k127_4623924_5	502025.Hoch_6881	6.076e-70	270.0	COG0164@1|root,COG0164@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS3_k127_4623924_12	690850.Desaf_0775	6.991e-11	75.0	COG5434@1|root,COG5434@2|Bacteria,1R1I5@1224|Proteobacteria,4320W@68525|delta/epsilon subdivisions,2WWIY@28221|Deltaproteobacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4623924_6	290397.Adeh_2471	1.06e-65	245.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2WM5N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4623924_8	502025.Hoch_6883	1.544e-49	179.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPZ9@28221|Deltaproteobacteria,2YV95@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_463107_0	502025.Hoch_4971	2.213e-154	504.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_463107_2	502025.Hoch_4970	3.898e-53	192.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2YVK3@29|Myxococcales	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS3_k127_463107_1	502025.Hoch_4969	3.073e-63	221.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2YYUB@29|Myxococcales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_4635331_1	1192034.CAP_4239	4.644e-120	403.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	2|Bacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_4635331_2	1242864.D187_004492	4.906e-93	342.0	COG4403@1|root,COG4403@2|Bacteria,1PR3F@1224|Proteobacteria,438MM@68525|delta/epsilon subdivisions,2X8SR@28221|Deltaproteobacteria,2YXA3@29|Myxococcales	28221|Deltaproteobacteria	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
CMS3_k127_4635331_4	378806.STAUR_6184	1.22e-37	162.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,438GN@68525|delta/epsilon subdivisions,2X3RG@28221|Deltaproteobacteria,2YWXM@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_4635331_3	224324.aq_220	1.841e-47	174.0	COG0756@1|root,COG0756@2|Bacteria,2G4CU@200783|Aquificae	200783|Aquificae	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS3_k127_4635331_0	448385.sce4541	2.322e-262	827.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2YUER@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS3_k127_4635331_5	502025.Hoch_3848	7.944e-36	138.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2YVRR@29|Myxococcales	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS3_k127_4639394_1	502025.Hoch_0217	1.359e-71	245.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YWJD@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_4639394_0	502025.Hoch_5305	4.288e-151	511.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
CMS3_k127_4639394_2	448385.sce7925	2.832e-61	223.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce7925|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4651210_3	502025.Hoch_2319	1.338e-84	285.0	COG1716@1|root,COG1716@2|Bacteria,1QJBG@1224|Proteobacteria,433TM@68525|delta/epsilon subdivisions,2X3EM@28221|Deltaproteobacteria,2YVQN@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_4651210_1	391625.PPSIR1_12428	1.127e-163	543.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,2YXV4@29|Myxococcales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS3_k127_4651210_0	502025.Hoch_4947	4.321e-175	557.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,2YUN0@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS3_k127_4651210_5	1487953.JMKF01000006_gene5798	3.235e-14	86.0	COG1357@1|root,COG1357@2|Bacteria,1G15H@1117|Cyanobacteria,1H95A@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_4651210_2	1191523.MROS_1507	1.472e-154	496.0	COG1048@1|root,COG1048@2|Bacteria	2|Bacteria	C	aconitate hydratase activity	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_4654448_4	502025.Hoch_2484	9.379e-25	105.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2Z2HK@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
CMS3_k127_4654448_3	502025.Hoch_2483	2.717e-26	115.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2YVTF@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS3_k127_4654448_0	502025.Hoch_2482	9.24e-175	563.0	COG0737@1|root,COG0737@2|Bacteria,1NDBC@1224|Proteobacteria,42V2W@68525|delta/epsilon subdivisions,2WS9M@28221|Deltaproteobacteria,2YV8Z@29|Myxococcales	28221|Deltaproteobacteria	F	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_4654448_2	1452718.JBOY01000059_gene1585	5.784e-35	139.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CMS3_k127_4654448_1	502025.Hoch_2233	2.166e-37	152.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,4347A@68525|delta/epsilon subdivisions,2X1TP@28221|Deltaproteobacteria,2YYDQ@29|Myxococcales	1224|Proteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
CMS3_k127_4657329_1	886293.Sinac_4842	1.058e-46	190.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS3_k127_4657329_2	502025.Hoch_6124	3.964e-40	153.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria,2YW3H@29|Myxococcales	28221|Deltaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS3_k127_4657329_0	1185876.BN8_06618	2.888e-119	407.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CMS3_k127_4690389_2	264462.Bd0254	1.568e-62	228.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342,ko:K03703,ko:K04096	ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DUF4357,GIY-YIG,RNase_T
CMS3_k127_4690389_0	502025.Hoch_4835	1.73e-187	631.0	COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,42NV8@68525|delta/epsilon subdivisions,2WJIW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DEAD_2	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
CMS3_k127_4690389_1	1254432.SCE1572_22680	1.495e-82	293.0	COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,43347@68525|delta/epsilon subdivisions,2X4FK@28221|Deltaproteobacteria,2YYXB@29|Myxococcales	28221|Deltaproteobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
CMS3_k127_4690389_3	1051501.AYTL01000031_gene1463	7.254e-08	60.0	COG0500@1|root,COG2226@2|Bacteria,1V9BF@1239|Firmicutes,4HK9K@91061|Bacilli,1ZGGF@1386|Bacillus	91061|Bacilli	Q	Methyltransferase domain	ydaC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_4690389_4	655815.ZPR_3783	2.086e-05	53.0	COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,1HWXI@117743|Flavobacteriia	976|Bacteroidetes	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
CMS3_k127_4698154_3	502025.Hoch_3217	1.173e-73	257.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2YU35@29|Myxococcales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS3_k127_4698154_2	502025.Hoch_3653	1.137e-113	374.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2YUX2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS3_k127_4698154_0	502025.Hoch_3652	1.638e-158	505.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,2YU4X@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS3_k127_4698154_1	502025.Hoch_3651	4.343e-126	430.0	COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2YVWN@29|Myxococcales	28221|Deltaproteobacteria	J	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_4698154_6	502025.Hoch_3219	6.442e-38	150.0	2BT02@1|root,32N40@2|Bacteria,1Q3JG@1224|Proteobacteria,439CC@68525|delta/epsilon subdivisions,2X4KJ@28221|Deltaproteobacteria,2Z05X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS3_k127_4698154_8	338963.Pcar_1964	0.000455	49.0	COG0745@1|root,COG0745@2|Bacteria,1QZ5N@1224|Proteobacteria,4307W@68525|delta/epsilon subdivisions,2X7RC@28221|Deltaproteobacteria,43UV3@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
CMS3_k127_4698154_4	1254432.SCE1572_02930	1.462e-52	200.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,42X9G@68525|delta/epsilon subdivisions,2WSQS@28221|Deltaproteobacteria,2YV88@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS3_k127_4698154_5	1242864.D187_004363	2.811e-43	167.0	COG1191@1|root,COG1191@2|Bacteria	2|Bacteria	K	sigma factor activity	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_4698154_7	502025.Hoch_3647	4.971e-25	105.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_4701492_0	502025.Hoch_4013	4.461e-138	457.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria,2YUVI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4701492_5	448385.sce4951	4.557e-38	166.0	2ANDU@1|root,31DCF@2|Bacteria,1QAIC@1224|Proteobacteria,43541@68525|delta/epsilon subdivisions,2X956@28221|Deltaproteobacteria,2Z1ZX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_4701492_3	1192034.CAP_6502	2.215e-68	260.0	COG1470@1|root,COG1470@2|Bacteria,1Q9IM@1224|Proteobacteria,434EQ@68525|delta/epsilon subdivisions,2WYS3@28221|Deltaproteobacteria,2Z0GH@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_4701492_4	502025.Hoch_4010	3.612e-47	172.0	2AGM5@1|root,316UC@2|Bacteria,1PY0S@1224|Proteobacteria,43509@68525|delta/epsilon subdivisions,2WZB6@28221|Deltaproteobacteria,2Z1RE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4701492_2	502025.Hoch_4009	3.623e-71	241.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2YV8E@29|Myxococcales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS3_k127_4701492_1	502025.Hoch_4008	8.489e-80	274.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2YUYC@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS3_k127_4701492_6	485915.Dret_2068	5.683e-31	122.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2M882@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_4706838_3	502025.Hoch_5776	4.011e-57	205.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42RAY@68525|delta/epsilon subdivisions,2WMP5@28221|Deltaproteobacteria,2Z311@29|Myxococcales	28221|Deltaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_4706838_0	502025.Hoch_5777	3.491e-74	266.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4706838_1	502025.Hoch_5441	4.628e-61	220.0	COG3266@1|root,COG3266@2|Bacteria,1R0AG@1224|Proteobacteria,43CSZ@68525|delta/epsilon subdivisions,2X80I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Collagen triple helix	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
CMS3_k127_4706838_4	269799.Gmet_1856	2.311e-52	196.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,43TNN@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	TIGRFAM cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS3_k127_4706838_2	502025.Hoch_5480	1.923e-60	222.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,2YVCX@29|Myxococcales	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CMS3_k127_4706838_5	502025.Hoch_5479	2.632e-43	168.0	COG4942@1|root,COG4942@2|Bacteria	2|Bacteria	D	peptidase	filA	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS3_k127_4706838_6	1242864.D187_006564	4.976e-34	139.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2YZGM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_4727115_4	1408303.JNJJ01000052_gene1647	2.308e-05	50.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_4727115_1	1297742.A176_05463	5.253e-38	160.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CMS3_k127_4727115_0	557599.MKAN_25740	4.759e-186	597.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,232FY@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_4727115_3	1254432.SCE1572_51465	7.318e-17	83.0	COG0838@1|root,COG0838@2|Bacteria,1PPP3@1224|Proteobacteria,42VF4@68525|delta/epsilon subdivisions,2WRIV@28221|Deltaproteobacteria,2Z22Z@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS3_k127_4737885_3	448385.sce3565	4.299e-51	198.0	COG2885@1|root,COG3391@1|root,COG5184@1|root,COG2885@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_4737885_11	84751.XP_007882496.1	7.187e-11	75.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38DMI@33154|Opisthokonta,3PF4P@4751|Fungi,3V643@5204|Basidiomycota	4751|Fungi	T	Si dkey-21a6.5	-	-	-	-	-	-	-	-	-	-	-	-	Ephrin_rec_like
CMS3_k127_4737885_5	344747.PM8797T_00177	1.069e-33	147.0	2ESRG@1|root,33K9V@2|Bacteria,2J33K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4737885_6	1307759.JOMJ01000004_gene2996	8.082e-22	98.0	COG1225@1|root,COG1225@2|Bacteria,1N16N@1224|Proteobacteria	1224|Proteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_4737885_17	1394178.AWOO02000002_gene1740	7.796e-05	47.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_4737885_9	1085623.GNIT_1336	1.676e-16	85.0	COG3832@1|root,COG3832@2|Bacteria,1QYT7@1224|Proteobacteria,1T3TM@1236|Gammaproteobacteria,46ATM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_4737885_15	525263.HMPREF0298_1241	5.769e-08	63.0	2DBMC@1|root,2Z9YC@2|Bacteria,2IQNQ@201174|Actinobacteria,22RCI@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4737885_14	518766.Rmar_2198	1.068e-09	64.0	COG3255@1|root,COG3255@2|Bacteria,4NYB1@976|Bacteroidetes	976|Bacteroidetes	I	Sterol-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_4737885_8	95619.PM1_0204850	7.775e-18	96.0	COG3315@1|root,COG3315@2|Bacteria,1RCET@1224|Proteobacteria,1S2A1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG3315 O-Methyltransferase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_4737885_0	391625.PPSIR1_38721	2.462e-88	302.0	COG2304@1|root,COG2304@2|Bacteria,1Q9UZ@1224|Proteobacteria,434MH@68525|delta/epsilon subdivisions,2WYYZ@28221|Deltaproteobacteria,2Z0YT@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_4737885_1	7739.XP_002606139.1	2.689e-75	270.0	KOG1216@1|root,KOG1217@1|root,KOG1216@2759|Eukaryota,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,48CY1@7711|Chordata	33208|Metazoa	T	EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_3,EGF_CA,Lectin_C,TIL
CMS3_k127_4737885_16	391625.PPSIR1_07992	3.892e-05	55.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_4737885_10	1122134.KB893650_gene1715	3.462e-13	72.0	COG5126@1|root,COG5126@2|Bacteria,1N188@1224|Proteobacteria,1SAIA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DTZ	signal transduction protein with EFhand domain	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5,EF-hand_6,EF-hand_7,EF-hand_8
CMS3_k127_4737885_7	483219.LILAB_15380	1.395e-21	101.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
CMS3_k127_4737885_4	391625.PPSIR1_40859	4.338e-41	163.0	2DSD6@1|root,33FM0@2|Bacteria,1PBXM@1224|Proteobacteria,43862@68525|delta/epsilon subdivisions,2X3FW@28221|Deltaproteobacteria,2YVX7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4774746_9	903814.ELI_2739	4.927e-15	74.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,25VBQ@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS3_k127_4774746_6	448385.sce3731	2.8e-65	228.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,2Z0D5@29|Myxococcales	28221|Deltaproteobacteria	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
CMS3_k127_4774746_3	448385.sce3730	3.523e-277	861.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2YXEU@29|Myxococcales	28221|Deltaproteobacteria	H	acetolactate synthase	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_4774746_4	1173028.ANKO01000094_gene2637	3.287e-262	818.0	COG0129@1|root,COG0129@2|Bacteria,1G0KD@1117|Cyanobacteria,1H8V6@1150|Oscillatoriales	1117|Cyanobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS3_k127_4774746_1	502025.Hoch_0066	6.549e-310	984.0	2C4IS@1|root,2Z81U@2|Bacteria,1MWZ8@1224|Proteobacteria,43CYA@68525|delta/epsilon subdivisions,2X86G@28221|Deltaproteobacteria,2YXH8@29|Myxococcales	28221|Deltaproteobacteria	S	Lantibiotic biosynthesis dehydratase C-term	-	-	-	ko:K20483	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	Lant_dehydr_C,Lant_dehydr_N
CMS3_k127_4774746_7	502025.Hoch_0448	8.974e-30	125.0	28YPV@1|root,2ZKHE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4774746_2	886293.Sinac_1156	1.117e-279	904.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4774746_0	391625.PPSIR1_37049	0.0	1245.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,433QQ@68525|delta/epsilon subdivisions,2WY7P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_4774746_10	502025.Hoch_4172	1.971e-10	70.0	COG1716@1|root,COG1716@2|Bacteria,1Q2JX@1224|Proteobacteria,433U4@68525|delta/epsilon subdivisions,2X3GN@28221|Deltaproteobacteria,2YW0G@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_4774746_8	247490.KSU1_B0003	4.158e-25	118.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_4774746_5	448385.sce2769	3.104e-146	466.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,42UEB@68525|delta/epsilon subdivisions,2WR1X@28221|Deltaproteobacteria,2YU0H@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_4776570_9	1192034.CAP_4200	3.067e-43	170.0	COG3537@1|root,COG3537@2|Bacteria,1MXCY@1224|Proteobacteria,43BAT@68525|delta/epsilon subdivisions,2X6PZ@28221|Deltaproteobacteria,2YX4I@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
CMS3_k127_4776570_2	502025.Hoch_3213	6.585e-139	455.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
CMS3_k127_4776570_3	502025.Hoch_3212	1.58e-123	404.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2YWX3@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS3_k127_4776570_5	502025.Hoch_3395	5.804e-89	317.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_3395|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4776570_0	502025.Hoch_3394	7.478e-261	826.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YUHY@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
CMS3_k127_4776570_4	502025.Hoch_3392	1.506e-95	317.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,43BH3@68525|delta/epsilon subdivisions,2X6VD@28221|Deltaproteobacteria,2Z3D7@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
CMS3_k127_4776570_7	502025.Hoch_3391	1.234e-49	185.0	COG0848@1|root,COG0848@2|Bacteria,1PYYB@1224|Proteobacteria,437A4@68525|delta/epsilon subdivisions,2X2EF@28221|Deltaproteobacteria,2Z2TJ@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_4776570_10	502025.Hoch_3390	1.482e-37	147.0	COG0848@1|root,COG0848@2|Bacteria,1NA7P@1224|Proteobacteria,42V1Q@68525|delta/epsilon subdivisions,2WSGW@28221|Deltaproteobacteria,2YY8R@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_4776570_1	1254432.SCE1572_18270	1.995e-160	510.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2YU1K@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CMS3_k127_4779441_0	502025.Hoch_4934	3.655e-173	548.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2YTTI@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_4779441_3	502025.Hoch_4935	2.494e-101	336.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2YUS2@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_4779441_8	502025.Hoch_4936	2.415e-21	96.0	2B0TN@1|root,31T65@2|Bacteria,1QQVP@1224|Proteobacteria,437AY@68525|delta/epsilon subdivisions,2WYT2@28221|Deltaproteobacteria,2Z0J5@29|Myxococcales	28221|Deltaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
CMS3_k127_4779441_5	502025.Hoch_5612	9.367e-39	160.0	2BK7J@1|root,32EMD@2|Bacteria,1QB42@1224|Proteobacteria,43E56@68525|delta/epsilon subdivisions,2WZRQ@28221|Deltaproteobacteria,2Z2M1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4779441_1	502025.Hoch_5614	7.635e-167	546.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2YU98@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS3_k127_4779441_6	502025.Hoch_5615	6.454e-35	156.0	2AIXH@1|root,319F5@2|Bacteria,1Q2IZ@1224|Proteobacteria,4385R@68525|delta/epsilon subdivisions,2X3FK@28221|Deltaproteobacteria,2YVWB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CMS3_k127_4779441_2	1242864.D187_008445	1.769e-117	404.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria,4340K@68525|delta/epsilon subdivisions,2X4FG@28221|Deltaproteobacteria,2YYX6@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
CMS3_k127_4779441_9	1177594.MIC448_700001	1.553e-11	70.0	COG1409@1|root,COG3204@1|root,COG1409@2|Bacteria,COG3204@2|Bacteria,2I94U@201174|Actinobacteria,4FN98@85023|Microbacteriaceae	201174|Actinobacteria	K	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
CMS3_k127_4779441_7	118161.KB235922_gene3936	4.101e-30	128.0	2C4HM@1|root,2ZFRV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4779441_4	1278073.MYSTI_03945	2.884e-72	267.0	COG0402@1|root,COG2374@1|root,COG3209@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,COG3209@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,LTD,TSP_3
CMS3_k127_4783471_6	391625.PPSIR1_30681	8.049e-83	294.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CMS3_k127_4783471_1	378806.STAUR_4285	1.98e-150	488.0	COG2960@1|root,COG2960@2|Bacteria,1R494@1224|Proteobacteria,43CJP@68525|delta/epsilon subdivisions,2X7U1@28221|Deltaproteobacteria,2YXZK@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_4783471_0	448385.sce2930	8.736e-196	627.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,430JB@68525|delta/epsilon subdivisions,2WVTU@28221|Deltaproteobacteria,2YWQ0@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_4783471_14	1121896.JMLU01000036_gene129	9.472e-17	91.0	COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,1I1P7@117743|Flavobacteriia,2NZWJ@237|Flavobacterium	976|Bacteroidetes	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS3_k127_4783471_9	1254432.SCE1572_31600	2.14e-43	173.0	29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,4383H@68525|delta/epsilon subdivisions,2X3DF@28221|Deltaproteobacteria,2YVJ0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4783471_13	521674.Plim_2820	1.521e-18	89.0	2DRK9@1|root,33C5C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4783471_3	1287276.X752_01795	2.893e-145	482.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2TR7P@28211|Alphaproteobacteria,43IKB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Xylulose kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
CMS3_k127_4783471_8	502025.Hoch_5331	1.288e-60	213.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,43F3T@68525|delta/epsilon subdivisions,2X9UG@28221|Deltaproteobacteria,2YV6A@29|Myxococcales	28221|Deltaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	-	-	-	-	-	-	-	-	-	-	-	-	ChaC
CMS3_k127_4783471_2	1192034.CAP_3456	9.843e-149	496.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42Q1R@68525|delta/epsilon subdivisions,2WM4U@28221|Deltaproteobacteria,2YWW8@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249,ko:K11731	ko00071,ko00280,ko00281,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00281,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R08089	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4783471_10	525904.Tter_1681	2.485e-43	172.0	COG2843@1|root,COG3103@1|root,COG2843@2|Bacteria,COG4991@2|Bacteria,2NPJI@2323|unclassified Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	2.7.11.1	ko:K07282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PGA_cap,SH3_3,SH3_4
CMS3_k127_4783471_12	391625.PPSIR1_19664	1.617e-30	135.0	COG1470@1|root,COG1470@2|Bacteria,1Q21G@1224|Proteobacteria,437PA@68525|delta/epsilon subdivisions,2X2XJ@28221|Deltaproteobacteria,2YX5A@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4783471_7	326427.Cagg_1771	2.77e-67	262.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_2
CMS3_k127_4783471_4	391625.PPSIR1_21719	1.722e-106	366.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CMS3_k127_4783471_5	391625.PPSIR1_21719	9.22e-103	355.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CMS3_k127_4795230_8	391625.PPSIR1_13375	1.3e-57	214.0	COG3356@1|root,COG3356@2|Bacteria,1Q66U@1224|Proteobacteria,4358C@68525|delta/epsilon subdivisions,2WZJF@28221|Deltaproteobacteria,2Z29I@29|Myxococcales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS3_k127_4795230_5	391625.PPSIR1_13375	1.955e-85	304.0	COG3356@1|root,COG3356@2|Bacteria,1Q66U@1224|Proteobacteria,4358C@68525|delta/epsilon subdivisions,2WZJF@28221|Deltaproteobacteria,2Z29I@29|Myxococcales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS3_k127_4795230_12	330214.NIDE0745	3.848e-31	142.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4795230_10	290397.Adeh_0447	8.02e-41	167.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4795230_13	404589.Anae109_4164	1.939e-10	67.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_4795230_7	234267.Acid_3322	2.422e-58	210.0	COG2846@1|root,COG2846@2|Bacteria,3Y4SU@57723|Acidobacteria	57723|Acidobacteria	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
CMS3_k127_4795230_1	448385.sce3280	3.939e-158	514.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2X7TS@28221|Deltaproteobacteria,2YXZZ@29|Myxococcales	28221|Deltaproteobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
CMS3_k127_4795230_14	471852.Tcur_0258	6.116e-08	60.0	COG2105@1|root,COG2105@2|Bacteria,2GUIC@201174|Actinobacteria,4EQEW@85012|Streptosporangiales	201174|Actinobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS3_k127_4795230_11	1122997.AUDD01000001_gene2413	1.027e-31	140.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4DNBW@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT,Nitroreductase
CMS3_k127_4795230_6	1123269.NX02_00985	1.414e-64	226.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2U70V@28211|Alphaproteobacteria,2K4UN@204457|Sphingomonadales	204457|Sphingomonadales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_4795230_3	1254432.SCE1572_47310	8.724e-97	325.0	COG1475@1|root,COG1475@2|Bacteria,1Q2AH@1224|Proteobacteria,437X8@68525|delta/epsilon subdivisions,2X9QN@28221|Deltaproteobacteria,2YUMN@29|Myxococcales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_4795230_2	502025.Hoch_0415	1.755e-114	391.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42N28@68525|delta/epsilon subdivisions,2WJVR@28221|Deltaproteobacteria,2Z336@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	hemU	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS3_k127_4795230_4	502025.Hoch_0414	1.407e-95	320.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WIWA@28221|Deltaproteobacteria,2Z33X@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS3_k127_4795230_9	502025.Hoch_0419	1.268e-53	203.0	COG4558@1|root,COG4558@2|Bacteria,1QTSV@1224|Proteobacteria,43CYE@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Periplasmic binding protein	hmuT	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_4795230_0	502025.Hoch_5520	7.175e-225	706.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
CMS3_k127_4816774_0	465541.ATCJ01000005_gene2058	5.556e-112	383.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria	201174|Actinobacteria	CG	Glycosyltransferase, MGT family	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
CMS3_k127_4816774_1	765912.Thimo_1441	7.565e-85	288.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS3_k127_4816774_2	1123261.AXDW01000007_gene2324	2.867e-39	157.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4816774_4	509635.N824_05815	2.45e-19	91.0	COG0236@1|root,COG0236@2|Bacteria,4PNC8@976|Bacteroidetes	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_4816774_3	765912.Thimo_1437	1.096e-31	127.0	COG2091@1|root,COG3321@1|root,COG2091@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria,1X0HS@135613|Chromatiales	135613|Chromatiales	Q	PFAM acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_4820218_11	502025.Hoch_3779	7.785e-10	71.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2YWMX@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1716	ECH_1
CMS3_k127_4820218_3	391625.PPSIR1_10405	4.409e-103	360.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2YWS8@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_4820218_0	502025.Hoch_3781	7.097e-168	537.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4820218_12	378806.STAUR_5828	9.511e-10	72.0	COG3055@1|root,COG3055@2|Bacteria,1Q957@1224|Proteobacteria,438WZ@68525|delta/epsilon subdivisions,2X9SM@28221|Deltaproteobacteria,2YY28@29|Myxococcales	28221|Deltaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
CMS3_k127_4820218_8	391625.PPSIR1_03638	5.557e-44	180.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	1224|Proteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_4820218_2	502025.Hoch_3724	1.446e-119	395.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2YWNS@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase, class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_4820218_6	502025.Hoch_3723	9.618e-60	230.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
CMS3_k127_4820218_13	1174528.JH992898_gene1559	1.879e-09	64.0	COG0642@1|root,COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1JH73@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_4820218_5	502025.Hoch_3722	2.198e-65	250.0	COG0457@1|root,COG0664@1|root,COG0457@2|Bacteria,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_4820218_10	502025.Hoch_3721	1.466e-10	67.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	nuoF	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
CMS3_k127_4820218_15	1293048.CBMB010000010_gene3725	5.923e-06	60.0	COG1520@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,arCOG02556@2157|Archaea,2XZQY@28890|Euryarchaeota,23X43@183963|Halobacteria	183963|Halobacteria	S	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_4820218_14	1429916.X566_04305	2.701e-08	64.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2TU29@28211|Alphaproteobacteria,3JQN5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	HEAT repeat	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_4820218_4	502025.Hoch_3719	3.1e-69	254.0	COG5495@1|root,COG5495@2|Bacteria,1RDUW@1224|Proteobacteria,43799@68525|delta/epsilon subdivisions,2X2CQ@28221|Deltaproteobacteria,2YVZN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
CMS3_k127_4820218_7	502025.Hoch_3718	2.873e-55	215.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,2YVKY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
CMS3_k127_4820218_1	502025.Hoch_3717	2.375e-163	524.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS3_k127_4820218_16	391625.PPSIR1_34962	0.0002336	53.0	COG3266@1|root,COG3266@2|Bacteria,1PYFJ@1224|Proteobacteria,435BK@68525|delta/epsilon subdivisions,2WZP2@28221|Deltaproteobacteria,2Z2G1@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4828909_10	1120956.JHZK01000012_gene3638	4.492e-17	94.0	COG1920@1|root,COG1920@2|Bacteria,1RJPN@1224|Proteobacteria,2UAA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
CMS3_k127_4828909_5	502025.Hoch_0060	1.106e-104	360.0	COG0391@1|root,COG0391@2|Bacteria,1NK78@1224|Proteobacteria	1224|Proteobacteria	S	LPPG Fo 2-phospho-L-lactate transferase	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
CMS3_k127_4828909_6	502025.Hoch_0061	1.122e-75	267.0	COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,4324K@68525|delta/epsilon subdivisions,2WY50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.12,6.3.2.17,6.3.2.31,6.3.2.34	ko:K12234,ko:K22099	ko00680,ko00790,ko01120,map00680,map00790,map01120	M00378,M00840	R00942,R02237,R04241,R09399,R09400	RC00064,RC00090,RC00141,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
CMS3_k127_4828909_7	502025.Hoch_0062	9.156e-70	258.0	COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria	1224|Proteobacteria	S	NADPH-dependent f420 reductase	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
CMS3_k127_4828909_3	247633.GP2143_01765	5.424e-120	394.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,1RQYQ@1236|Gammaproteobacteria,1J5B4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_4828909_4	35754.JNYJ01000003_gene6578	1.461e-105	364.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4DAS8@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_4828909_8	525368.HMPREF0591_6223	4.547e-43	178.0	COG0204@1|root,COG0204@2|Bacteria,2GNBB@201174|Actinobacteria,23691@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_4828909_2	1278073.MYSTI_04824	2.49e-122	400.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,437H0@68525|delta/epsilon subdivisions,2X2QC@28221|Deltaproteobacteria,2YXMK@29|Myxococcales	28221|Deltaproteobacteria	P	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_4828909_9	391625.PPSIR1_28686	1.625e-25	113.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	kstR	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_4828909_1	1323361.JPOC01000033_gene1501	5e-139	478.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FV7A@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_4828909_0	1149133.ppKF707_2621	2.463e-182	606.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1YJDT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_4832581_16	502025.Hoch_4879	6.092e-67	245.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_4832581_6	502025.Hoch_5137	1.521e-136	473.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS3_k127_4832581_21	1163407.UU7_05574	1.338e-50	184.0	COG1522@1|root,COG1522@2|Bacteria,1RJK0@1224|Proteobacteria,1S6HD@1236|Gammaproteobacteria,1X6QR@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
CMS3_k127_4832581_11	1121428.DESHY_110193___1	1.991e-98	335.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia,262MF@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_4832581_29	1110502.TMO_0240	1.423e-24	108.0	COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,2UA2S@28211|Alphaproteobacteria,2JTVM@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS3_k127_4832581_4	342113.DM82_1795	1.769e-146	491.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,1KDQ8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_4832581_22	502025.Hoch_6704	8.667e-50	197.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_6704|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4832581_5	502025.Hoch_6599	2.958e-142	459.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydrogenase chorismate mutase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
CMS3_k127_4832581_33	399549.Msed_0681	2.354e-16	92.0	COG0644@1|root,arCOG00570@2157|Archaea,2XPWV@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,Trp_halogenase
CMS3_k127_4832581_9	1382359.JIAL01000001_gene3006	1.703e-117	406.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS3_k127_4832581_24	388413.ALPR1_21202	8.402e-39	158.0	COG2234@1|root,COG2234@2|Bacteria,4NMH1@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_4832581_36	929703.KE386491_gene2777	4.073e-15	86.0	28N7K@1|root,2ZBC9@2|Bacteria,4NHU8@976|Bacteroidetes,47N9I@768503|Cytophagia	976|Bacteroidetes	S	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_4832581_17	234267.Acid_0434	3.622e-59	224.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,FAD_oxidored,GMC_oxred_C,GMC_oxred_N
CMS3_k127_4832581_35	1192034.CAP_0553	1.229e-15	84.0	2AH09@1|root,31793@2|Bacteria,1PYJ1@1224|Proteobacteria,435DZ@68525|delta/epsilon subdivisions,2WZRH@28221|Deltaproteobacteria,2Z2KK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4832581_32	580332.Slit_1110	1.083e-16	93.0	COG4848@1|root,COG4848@2|Bacteria,1NE0R@1224|Proteobacteria,2VXNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0354 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1444
CMS3_k127_4832581_10	1122603.ATVI01000005_gene3858	1.622e-103	343.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RYF6@1236|Gammaproteobacteria,1X6VE@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4832581_13	1254432.SCE1572_17640	1.445e-86	294.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4832581_3	502025.Hoch_0562	3.757e-157	503.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2Z073@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_4832581_0	502025.Hoch_0561	4.448e-283	895.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2YW51@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
CMS3_k127_4832581_2	502025.Hoch_0560	3.955e-178	565.0	COG1453@1|root,COG1453@2|Bacteria,1QZ5K@1224|Proteobacteria,43CG9@68525|delta/epsilon subdivisions,2X7RA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
CMS3_k127_4832581_23	502025.Hoch_4938	1.785e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,1Q4ZI@1224|Proteobacteria,42TYH@68525|delta/epsilon subdivisions,2WQNG@28221|Deltaproteobacteria,2YYP8@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	carQ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_4832581_34	502025.Hoch_1117	5.391e-16	85.0	2ANH0@1|root,31DFR@2|Bacteria,1QAP5@1224|Proteobacteria,43E2N@68525|delta/epsilon subdivisions,2WZIE@28221|Deltaproteobacteria,2Z27P@29|Myxococcales	502025.Hoch_1117|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4832581_26	404589.Anae109_2205	2.907e-33	136.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,42UKS@68525|delta/epsilon subdivisions,2WQV2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
CMS3_k127_4832581_7	502025.Hoch_5948	6.396e-128	421.0	COG3563@1|root,COG3563@2|Bacteria,1MW0T@1224|Proteobacteria,42PXV@68525|delta/epsilon subdivisions,2WNAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Capsule polysaccharide biosynthesis protein	-	-	-	ko:K07266	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS3_k127_4832581_19	502025.Hoch_3169	2.418e-52	193.0	COG0262@1|root,COG0262@2|Bacteria,1RH02@1224|Proteobacteria,43ACN@68525|delta/epsilon subdivisions,2X5SI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS3_k127_4832581_31	1192034.CAP_4084	5.707e-17	92.0	COG3391@1|root,COG3391@2|Bacteria,1Q2JN@1224|Proteobacteria,4386H@68525|delta/epsilon subdivisions,2X9ZH@28221|Deltaproteobacteria,2YVZH@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Stig1
CMS3_k127_4832581_40	391625.PPSIR1_07268	1.643e-06	60.0	2AJJV@1|root,31A6Q@2|Bacteria,1Q51M@1224|Proteobacteria,435IH@68525|delta/epsilon subdivisions,2WZW5@28221|Deltaproteobacteria,2Z2VC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4832581_28	448385.sce7743	1.49e-27	127.0	COG1595@1|root,COG1595@2|Bacteria,1QA32@1224|Proteobacteria,434TA@68525|delta/epsilon subdivisions,2WZ4A@28221|Deltaproteobacteria,2Z1AN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4832581_37	1242864.D187_000180	2.319e-13	85.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4832581_12	391625.PPSIR1_21769	1.729e-89	308.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,RCC1_2
CMS3_k127_4832581_41	1089439.KB902239_gene506	0.0009726	42.0	2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4832581_1	290397.Adeh_3959	5.981e-229	724.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2YU49@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
CMS3_k127_4832581_20	1089553.Tph_c01630	4.015e-52	188.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,42GMY@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS3_k127_4832581_8	945713.IALB_2266	2.212e-122	400.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2,Thioredoxin
CMS3_k127_4832581_30	502025.Hoch_4460	1.121e-20	98.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_4833641_7	502025.Hoch_2542	5.207e-158	505.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2YXED@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_4833641_24	7165.AGAP005065-PA	1.551e-09	70.0	COG5640@1|root,KOG3627@2759|Eukaryota,38VP7@33154|Opisthokonta,3C5Z0@33208|Metazoa,3DM0X@33213|Bilateria,425EX@6656|Arthropoda,3SRQZ@50557|Insecta,456GJ@7147|Diptera,45JXC@7148|Nematocera	33208|Metazoa	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_4833641_18	502025.Hoch_1830	3.16e-19	104.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_4833641_23	1242864.D187_002533	1.058e-09	72.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_4833641_20	310453.XP_007586495.1	4.398e-13	76.0	COG2940@1|root,KOG1083@2759|Eukaryota,38HZ1@33154|Opisthokonta,3NYRQ@4751|Fungi,3QMGW@4890|Ascomycota,20432@147541|Dothideomycetes	4751|Fungi	K	Cysteine-rich motif following a subset of SET domains	-	-	2.1.1.43,2.3.1.225	ko:K06101,ko:K16675	ko00310,ko04391,map00310,map04391	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	SET
CMS3_k127_4833641_9	269799.Gmet_1640	7.382e-126	412.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,43TVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_4833641_19	502025.Hoch_4155	6.665e-14	86.0	COG4969@1|root,COG4969@2|Bacteria,1R0CQ@1224|Proteobacteria,43CV8@68525|delta/epsilon subdivisions,2X835@28221|Deltaproteobacteria,2Z3JW@29|Myxococcales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
CMS3_k127_4833641_1	502025.Hoch_3814	9.272e-291	916.0	COG0784@1|root,COG2199@1|root,COG2203@1|root,COG3437@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS3_k127_4833641_3	502025.Hoch_3813	3.326e-201	669.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42N2U@68525|delta/epsilon subdivisions,2WJRR@28221|Deltaproteobacteria,2YXAZ@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	msbA1	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4833641_2	502025.Hoch_3812	5.797e-208	661.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,2YWGZ@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4833641_0	502025.Hoch_3816	0.0	3735.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,4391J@68525|delta/epsilon subdivisions,2X472@28221|Deltaproteobacteria,2YYDY@29|Myxococcales	28221|Deltaproteobacteria	GO	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
CMS3_k127_4833641_21	1463853.JOHW01000019_gene1825	7.1e-13	80.0	COG1716@1|root,COG1716@2|Bacteria,2HPF7@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,FHA
CMS3_k127_4833641_25	1278073.MYSTI_00468	9.713e-05	50.0	COG0558@1|root,COG2246@1|root,COG0558@2|Bacteria,COG2246@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria,2YWYE@29|Myxococcales	28221|Deltaproteobacteria	I	GtrA-like protein	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,GtrA
CMS3_k127_4833641_22	1123278.KB893388_gene5692	3.701e-10	70.0	COG3047@1|root,COG3047@2|Bacteria,4NSNH@976|Bacteroidetes,47R79@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
CMS3_k127_4833641_10	502025.Hoch_1966	4.056e-103	366.0	COG1413@1|root,COG1413@2|Bacteria,1PYBK@1224|Proteobacteria,43E33@68525|delta/epsilon subdivisions,2WZJM@28221|Deltaproteobacteria,2Z29W@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_4833641_14	1242864.D187_005930	2.474e-67	264.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria	1224|Proteobacteria	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS3_k127_4833641_17	502025.Hoch_6453	7.993e-23	108.0	28W5H@1|root,2ZI6A@2|Bacteria,1QBFX@1224|Proteobacteria,435GD@68525|delta/epsilon subdivisions,2WZTW@28221|Deltaproteobacteria,2Z2QX@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS3_k127_4833641_11	1123368.AUIS01000025_gene1492	3.3e-94	319.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,2NC5Z@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS3_k127_4833641_5	502025.Hoch_2394	1.727e-170	554.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,2YU84@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS3_k127_4833641_16	502025.Hoch_2395	1.797e-33	132.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS3_k127_4833641_12	1254432.SCE1572_27340	2.144e-92	327.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2YU0A@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_4833641_8	502025.Hoch_2397	1.698e-148	483.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2YUZD@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_4833641_4	502025.Hoch_2398	3.567e-187	601.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,2YTVE@29|Myxococcales	28221|Deltaproteobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_4833641_13	1283300.ATXB01000001_gene1869	1.689e-75	262.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1XEP3@135618|Methylococcales	135618|Methylococcales	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS3_k127_4833641_15	1123236.KB899376_gene1159	7.834e-42	161.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,4677T@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS3_k127_4833641_6	1297742.A176_02362	6.454e-163	523.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS3_k127_4841058_1	502025.Hoch_5520	3.191e-17	80.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
CMS3_k127_4841058_0	502025.Hoch_5776	1.057e-166	548.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42RAY@68525|delta/epsilon subdivisions,2WMP5@28221|Deltaproteobacteria,2Z311@29|Myxococcales	28221|Deltaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_4841058_2	502025.Hoch_5777	2.784e-13	84.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4841638_9	1229780.BN381_80295	3.261e-92	315.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_4841638_14	502025.Hoch_0064	8.736e-53	197.0	COG1309@1|root,COG1309@2|Bacteria,1NP72@1224|Proteobacteria,42T8H@68525|delta/epsilon subdivisions,2WPNA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS3_k127_4841638_17	391165.GbCGDNIH1_0247	4.886e-36	154.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS3_k127_4841638_25	391625.PPSIR1_25576	8.268e-12	78.0	COG4633@1|root,COG4633@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
CMS3_k127_4841638_5	502025.Hoch_0262	8.05e-138	465.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_4841638_19	502025.Hoch_0263	9.122e-29	116.0	COG0271@1|root,COG0271@2|Bacteria,1R3MQ@1224|Proteobacteria,43DKY@68525|delta/epsilon subdivisions,2X8S4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS3_k127_4841638_7	1297742.A176_04476	3.898e-96	349.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4841638_3	502025.Hoch_0264	2.705e-227	715.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YU0C@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_4841638_20	710685.MycrhN_5533	2.019e-27	130.0	COG3178@1|root,COG3178@2|Bacteria,2GN8T@201174|Actinobacteria,23F8B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
CMS3_k127_4841638_27	425104.Ssed_4015	9.344e-12	78.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,2Q9VQ@267890|Shewanellaceae	1236|Gammaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0009266,GO:0009628,GO:0009898,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0019725,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0042221,GO:0042493,GO:0042592,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0071502,GO:0071840,GO:0071944,GO:0098552,GO:0098562,GO:0140096	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	iECSE_1348.ECSE_4435	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
CMS3_k127_4841638_16	1192034.CAP_8210	1.902e-43	161.0	COG4270@1|root,COG4270@2|Bacteria,1NAUW@1224|Proteobacteria,4385E@68525|delta/epsilon subdivisions,2X3FE@28221|Deltaproteobacteria,2YVUU@29|Myxococcales	28221|Deltaproteobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS3_k127_4841638_31	272942.RCAP_rcc02638	5.87e-06	57.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2VAV1@28211|Alphaproteobacteria,1FC50@1060|Rhodobacter	28211|Alphaproteobacteria	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_4841638_32	1144275.COCOR_00495	3.044e-05	58.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,Cadherin-like,DUF3494,Esterase_phd,Flg_new,RCC1,RCC1_2,SLH
CMS3_k127_4841638_30	3055.EDO97194	1.622e-07	65.0	KOG4569@1|root,KOG4569@2759|Eukaryota	2759|Eukaryota	G	phospholipase A1 activity	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
CMS3_k127_4841638_2	502025.Hoch_0026	1.274e-270	846.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CMS3_k127_4841638_0	502025.Hoch_0025	8.504e-297	929.0	COG3973@1|root,COG3973@2|Bacteria,1P638@1224|Proteobacteria,42MXR@68525|delta/epsilon subdivisions,2WK1Z@28221|Deltaproteobacteria,2Z32G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD_C_2
CMS3_k127_4841638_24	1117108.PAALTS15_01262	7.525e-14	86.0	COG0454@1|root,COG0456@2|Bacteria,1UZC5@1239|Firmicutes,4HFDR@91061|Bacilli,26UAI@186822|Paenibacillaceae	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
CMS3_k127_4841638_29	316274.Haur_4335	1.41e-09	72.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi,37544@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20,fn3
CMS3_k127_4841638_22	1469557.JSWF01000045_gene472	9.114e-17	96.0	COG2356@1|root,COG2356@2|Bacteria,4NINJ@976|Bacteroidetes,1HZEY@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CMS3_k127_4841638_12	483219.LILAB_10430	2.564e-55	222.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YY0K@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
CMS3_k127_4841638_13	926560.KE387023_gene2235	1.473e-54	200.0	COG0454@1|root,COG0456@2|Bacteria,1WMPD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,FR47
CMS3_k127_4841638_26	1306990.BARG01000042_gene4916	8.942e-12	80.0	COG5555@1|root,COG5555@2|Bacteria,2GKZ9@201174|Actinobacteria	201174|Actinobacteria	N	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
CMS3_k127_4841638_6	502025.Hoch_0215	2.621e-112	407.0	COG3419@1|root,COG3419@2|Bacteria	2|Bacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilC	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
CMS3_k127_4841638_1	502025.Hoch_5222	3.298e-287	888.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJBM@28221|Deltaproteobacteria,2YTUN@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS3_k127_4841638_8	502025.Hoch_0553	1.064e-92	314.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,43AKH@68525|delta/epsilon subdivisions,2WW5J@28221|Deltaproteobacteria,2YV4B@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS3_k127_4841638_10	502025.Hoch_0552	4.102e-83	282.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,42S73@68525|delta/epsilon subdivisions,2WNPE@28221|Deltaproteobacteria,2YV3B@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_4841638_15	391625.PPSIR1_26061	9.875e-50	190.0	COG0144@1|root,COG0144@2|Bacteria	2|Bacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
CMS3_k127_4841638_4	880073.Calab_3750	1.698e-155	527.0	COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972,ko:K10754	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	M00289,M00295	R00382	RC00005	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS3_k127_4841638_23	591158.SSMG_02932	6.999e-15	78.0	2B0P2@1|root,31T0U@2|Bacteria,2GRH2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4841638_33	317655.Sala_2510	3.138e-05	53.0	COG2608@1|root,COG2608@2|Bacteria,1RDCB@1224|Proteobacteria,2UCEK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	mercuric transport protein	-	-	-	ko:K08363	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	MerT
CMS3_k127_4841638_18	1122138.AQUZ01000002_gene2113	3.16e-34	136.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria,4DWMH@85009|Propionibacteriales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS3_k127_4841638_11	1254432.SCE1572_07655	1.408e-57	212.0	COG0703@1|root,COG3620@1|root,COG0703@2|Bacteria,COG3620@2|Bacteria,1MX66@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	-	ko:K15546	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31,SKI
CMS3_k127_4841638_21	502025.Hoch_5224	4.312e-21	93.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_4842879_1	1265505.ATUG01000001_gene4392	4.58e-41	157.0	2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
CMS3_k127_4842879_2	187303.BN69_2421	3.521e-34	138.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4842879_3	357808.RoseRS_1610	5.68e-07	62.0	COG0739@1|root,COG1470@1|root,COG5479@1|root,COG0739@2|Bacteria,COG1470@2|Bacteria,COG5479@2|Bacteria	2|Bacteria	M	isomerase activity	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF4384,LGFP,OapA,OapA_N,PEGA,Peptidase_M23
CMS3_k127_4842879_0	502025.Hoch_0113	5.784e-131	423.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2YU10@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS3_k127_4845307_7	1151117.AJLF01000001_gene1492	2.015e-09	68.0	arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
CMS3_k127_4845307_4	502025.Hoch_2678	1.286e-32	137.0	COG0633@1|root,COG0633@2|Bacteria,1NJZK@1224|Proteobacteria,42XW4@68525|delta/epsilon subdivisions,2WT8P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS3_k127_4845307_3	290397.Adeh_4231	1.872e-39	153.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,42VWF@68525|delta/epsilon subdivisions,2WRX8@28221|Deltaproteobacteria,2YVKZ@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
CMS3_k127_4845307_1	502025.Hoch_5692	7.848e-93	315.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,42NY0@68525|delta/epsilon subdivisions,2X3G8@28221|Deltaproteobacteria,2YVYR@29|Myxococcales	28221|Deltaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CMS3_k127_4845307_0	502025.Hoch_5693	2.493e-174	563.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_5,DUF285,DUF5011,F5_F8_type_C,Flg_new,LRR_5,NPCBM,Peptidase_M60
CMS3_k127_4845307_2	502025.Hoch_5696	7.208e-90	311.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria	1224|Proteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CMS3_k127_4846365_1	1254432.SCE1572_34165	1.596e-85	301.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_34165|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_4846365_2	1201293.AKXQ01000003_gene2495	8.476e-10	73.0	COG4188@1|root,COG4188@2|Bacteria,1QUVG@1224|Proteobacteria,1T22C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N,PAF-AH_p_II
CMS3_k127_4846365_0	1254432.SCE1572_06465	3.602e-175	582.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4850049_4	693986.MOC_0408	3.851e-25	121.0	COG2267@1|root,COG2267@2|Bacteria,1MW9H@1224|Proteobacteria,2U1YC@28211|Alphaproteobacteria,1JRVA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4850049_3	502025.Hoch_0476	1.365e-49	188.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,42WB9@68525|delta/epsilon subdivisions,2WQ0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM PHA accumulation regulator DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
CMS3_k127_4850049_0	502025.Hoch_0478	1.473e-181	580.0	COG4145@1|root,COG4145@2|Bacteria,1PG56@1224|Proteobacteria,42YZC@68525|delta/epsilon subdivisions,2WTWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_4850049_2	315749.Bcer98_1044	1.319e-68	248.0	COG3243@1|root,COG3243@2|Bacteria,1V0SA@1239|Firmicutes,4HCRB@91061|Bacilli,1ZAX8@1386|Bacillus	91061|Bacilli	I	Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_4850049_1	502025.Hoch_0481	2.018e-111	364.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
CMS3_k127_485850_0	502025.Hoch_1780	5e-324	1011.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS3_k127_485850_2	502025.Hoch_0551	6.182e-106	354.0	COG1388@1|root,COG3770@1|root,COG1388@2|Bacteria,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,42VK7@68525|delta/epsilon subdivisions,2WS1M@28221|Deltaproteobacteria,2YVMA@29|Myxococcales	28221|Deltaproteobacteria	M	LysM domain protein	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M74
CMS3_k127_485850_3	84531.JMTZ01000023_gene4233	1.006e-92	337.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1X499@135614|Xanthomonadales	1236|Gammaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
CMS3_k127_485850_1	1254432.SCE1572_45120	1.402e-165	556.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_485850_4	1192034.CAP_4468	8.024e-80	278.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,43AKE@68525|delta/epsilon subdivisions,2WMV2@28221|Deltaproteobacteria,2YZQY@29|Myxococcales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_485850_7	1443665.JACA01000003_gene903	2.79e-10	72.0	2A6K5@1|root,30VDT@2|Bacteria,4NMRY@976|Bacteroidetes,1I2ZW@117743|Flavobacteriia,2YIGG@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_485850_6	391625.PPSIR1_35392	2.897e-24	116.0	COG5640@1|root,COG5640@2|Bacteria,1N2J1@1224|Proteobacteria	1224|Proteobacteria	M	COG5640 Secreted trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_485850_5	448385.sce9161	1.434e-59	220.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4859408_7	1146883.BLASA_1468	2.045e-11	71.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	sgaR	-	-	ko:K02479,ko:K07684,ko:K07685	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_4859408_0	886293.Sinac_1156	1.063e-290	934.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4859408_2	391625.PPSIR1_24619	6.982e-118	397.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,42PAQ@68525|delta/epsilon subdivisions,2WMYT@28221|Deltaproteobacteria,2Z2BP@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_4859408_4	756272.Plabr_3356	4.976e-60	231.0	COG0596@1|root,COG0596@2|Bacteria,2IZ5A@203682|Planctomycetes	203682|Planctomycetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4859408_1	530564.Psta_4360	6.755e-159	521.0	COG2141@1|root,COG2141@2|Bacteria,2J00I@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_4859408_3	1463825.JNXC01000002_gene4648	4.312e-95	322.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4DZQJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_NADP
CMS3_k127_4859408_6	391625.PPSIR1_16195	1.497e-40	152.0	COG0760@1|root,COG0760@2|Bacteria,1Q4IW@1224|Proteobacteria,43A0D@68525|delta/epsilon subdivisions,2X2FD@28221|Deltaproteobacteria,2Z2B6@29|Myxococcales	28221|Deltaproteobacteria	M	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_3
CMS3_k127_4859408_5	502025.Hoch_2723	1.106e-53	194.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2Z0NX@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
CMS3_k127_4859645_0	502025.Hoch_2608	8.912e-143	471.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_4863721_27	1218084.BBJK01000004_gene585	3.265e-14	76.0	COG1917@1|root,COG1917@2|Bacteria,1NHA7@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4437)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4437
CMS3_k127_4863721_17	404589.Anae109_3542	1.885e-49	185.0	2DN8B@1|root,32W2U@2|Bacteria,1R03I@1224|Proteobacteria,42XCH@68525|delta/epsilon subdivisions,2WT8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4863721_23	502025.Hoch_5244	2.066e-27	132.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS,Ub-Mut7C
CMS3_k127_4863721_0	502025.Hoch_5245	0.0	1043.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,4347Y@68525|delta/epsilon subdivisions,2X9D5@28221|Deltaproteobacteria,2Z1DR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS3_k127_4863721_12	502025.Hoch_5264	1.087e-72	282.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,42PSZ@68525|delta/epsilon subdivisions,2WMBH@28221|Deltaproteobacteria,2YVSB@29|Myxococcales	28221|Deltaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS3_k127_4863721_7	502025.Hoch_5265	2.344e-102	364.0	COG4775@1|root,COG4775@2|Bacteria,1QX52@1224|Proteobacteria,43BXS@68525|delta/epsilon subdivisions,2X78I@28221|Deltaproteobacteria,2Z3DY@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
CMS3_k127_4863721_20	1254432.SCE1572_04015	4.259e-35	156.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-2	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_4863721_24	1254432.SCE1572_04010	4.216e-24	111.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42TAW@68525|delta/epsilon subdivisions,2WP4Q@28221|Deltaproteobacteria,2Z2DP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS3_k127_4863721_4	344747.PM8797T_05550	1.227e-119	393.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IZS3@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
CMS3_k127_4863721_19	1240350.AMZE01000019_gene1205	1.806e-43	166.0	COG0500@1|root,COG0500@2|Bacteria,1RAE4@1224|Proteobacteria,1S0RC@1236|Gammaproteobacteria,1YVGJ@136845|Pseudomonas putida group	1236|Gammaproteobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family	tpm	GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
CMS3_k127_4863721_6	102125.Xen7305DRAFT_00001820	1.498e-102	341.0	COG0491@1|root,COG1141@1|root,COG0491@2|Bacteria,COG1141@2|Bacteria,1G3D1@1117|Cyanobacteria,3VIAS@52604|Pleurocapsales	1117|Cyanobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
CMS3_k127_4863721_13	243090.RB5029	4.854e-70	257.0	COG4798@1|root,COG4798@2|Bacteria,2IYU0@203682|Planctomycetes	203682|Planctomycetes	S	COG2226 Methylase involved in ubiquinone menaquinone	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_4863721_22	502025.Hoch_4490	3.663e-32	130.0	COG3703@1|root,COG3703@2|Bacteria	2|Bacteria	P	gamma-glutamylcyclotransferase activity	ykqA	-	-	-	-	-	-	-	-	-	-	-	AIG2_2,GGACT
CMS3_k127_4863721_11	290397.Adeh_0738	1.013e-72	267.0	COG0122@1|root,COG0122@2|Bacteria,1P0FP@1224|Proteobacteria	1224|Proteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS3_k127_4863721_3	502025.Hoch_4485	6.497e-126	425.0	COG1086@1|root,COG1215@1|root,COG1086@2|Bacteria,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QGX@68525|delta/epsilon subdivisions,2WJPU@28221|Deltaproteobacteria,2YV0M@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4863721_10	1379698.RBG1_1C00001G1631	1.471e-73	263.0	COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria	2|Bacteria	E	Metallopeptidase family M24	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_4863721_21	649638.Trad_1722	5.959e-35	152.0	COG2267@1|root,COG2267@2|Bacteria,1WIH1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
CMS3_k127_4863721_1	1278073.MYSTI_01686	2.556e-156	510.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42ZA9@68525|delta/epsilon subdivisions,2WU3B@28221|Deltaproteobacteria,2YU7S@29|Myxococcales	28221|Deltaproteobacteria	KT	GAF domain	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GAF_3,HTH_8,Sigma54_activat
CMS3_k127_4863721_15	107635.AZUO01000001_gene1386	9.355e-61	213.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2U5EA@28211|Alphaproteobacteria,36YXA@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS3_k127_4863721_16	290397.Adeh_0767	6.491e-51	192.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
CMS3_k127_4863721_8	502025.Hoch_4484	7.238e-101	333.0	COG5424@1|root,COG5424@2|Bacteria,1Q9R2@1224|Proteobacteria,434J3@68525|delta/epsilon subdivisions,2X8WX@28221|Deltaproteobacteria,2Z0SN@29|Myxococcales	28221|Deltaproteobacteria	H	Iron-containing redox enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
CMS3_k127_4863721_9	1192034.CAP_1511	1.908e-96	335.0	COG0265@1|root,COG0515@1|root,COG3287@1|root,COG0265@2|Bacteria,COG0515@2|Bacteria,COG3287@2|Bacteria,1PEIZ@1224|Proteobacteria,433VS@68525|delta/epsilon subdivisions,2X3Q2@28221|Deltaproteobacteria,2YWTJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PDZ_2,Pkinase
CMS3_k127_4863721_14	1192034.CAP_7213	9.449e-69	252.0	COG4580@1|root,COG4580@2|Bacteria	2|Bacteria	M	maltodextrin transmembrane transporter activity	lamB	-	-	ko:K02024	-	-	-	-	ko00000,ko02000	1.B.3.1.1	-	-	LamB,Porin_8,Sugarporin_N
CMS3_k127_4863721_2	1192034.CAP_7214	5.965e-151	518.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,433VR@68525|delta/epsilon subdivisions,2X3PU@28221|Deltaproteobacteria,2YWT2@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
CMS3_k127_4863721_5	391625.PPSIR1_23404	1.254e-107	367.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2Z2WE@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_4863721_18	1313301.AUGC01000007_gene578	4.753e-44	175.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
CMS3_k127_4863721_25	596323.HMPREF0554_0653	6.341e-15	83.0	COG2077@1|root,COG2077@2|Bacteria,37A77@32066|Fusobacteria	32066|Fusobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_4866536_4	247490.KSU1_C1622	3.839e-113	370.0	COG1730@1|root,COG1730@2|Bacteria	2|Bacteria	O	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
CMS3_k127_4866536_0	909663.KI867150_gene300	4.828e-225	720.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MR4V@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS3_k127_4866536_10	585394.RHOM_06830	1.1e-16	82.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS3_k127_4866536_14	1192034.CAP_7630	7.825e-05	53.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YY0K@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
CMS3_k127_4866536_5	1297742.A176_03832	2.983e-69	254.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MWRF@1224|Proteobacteria,42P9S@68525|delta/epsilon subdivisions,2WJI7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12
CMS3_k127_4866536_9	483219.LILAB_15385	7.804e-21	105.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_4866536_11	1144275.COCOR_07153	9.569e-10	71.0	COG3391@1|root,COG3391@2|Bacteria,1QX9W@1224|Proteobacteria,43C32@68525|delta/epsilon subdivisions,2X7DQ@28221|Deltaproteobacteria,2YVS2@29|Myxococcales	28221|Deltaproteobacteria	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
CMS3_k127_4866536_1	1254432.SCE1572_45120	1.389e-176	590.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_4866536_12	448385.sce3564	2.52e-07	64.0	COG1361@1|root,COG3055@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,DUF11,HYR,NPCBM_assoc,OmpA,OmpA_membrane
CMS3_k127_4866536_8	96561.Dole_0490	6.1e-24	119.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WKJV@28221|Deltaproteobacteria,2MHMF@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
CMS3_k127_4866536_13	485917.Phep_3746	4.545e-05	51.0	COG1361@1|root,COG2133@1|root,COG3291@1|root,COG4625@1|root,COG1361@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NDZC@976|Bacteroidetes,1IRJP@117747|Sphingobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,DUF11,He_PIG,fn3
CMS3_k127_4866536_2	1254432.SCE1572_45120	1.319e-159	538.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_4866536_3	937777.Deipe_0633	4.177e-132	430.0	COG0039@1|root,COG0039@2|Bacteria,1WJHY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS3_k127_4866536_6	502025.Hoch_5147	1.439e-59	208.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2YU09@29|Myxococcales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
CMS3_k127_4883402_11	1254432.SCE1572_14240	1.037e-41	175.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1QA6R@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4883402_10	502025.Hoch_5893	3.729e-62	224.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	1224|Proteobacteria	T	SMART protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_4883402_13	1030157.AFMP01000064_gene2191	0.0002437	51.0	COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2UJ8K@28211|Alphaproteobacteria,2KDGQ@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_4883402_5	927677.ALVU02000008_gene18	1.048e-92	323.0	COG0412@1|root,COG0412@2|Bacteria,1GGA6@1117|Cyanobacteria	1117|Cyanobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_4883402_7	1278073.MYSTI_03226	1.854e-76	271.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,42QS8@68525|delta/epsilon subdivisions,2WMV7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CMS3_k127_4883402_1	314230.DSM3645_07745	2.017e-234	734.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS3_k127_4883402_9	502025.Hoch_6087	1.897e-63	228.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,42ME7@68525|delta/epsilon subdivisions,2WSGX@28221|Deltaproteobacteria,2YW1S@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_4883402_2	1177181.T9A_02383	2.363e-164	526.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,1RNDU@1236|Gammaproteobacteria,1XMS6@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4883402_0	886293.Sinac_1156	9.511e-240	788.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4883402_6	1173024.KI912150_gene1249	4.747e-79	269.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1JJWX@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS3_k127_4883402_8	1121104.AQXH01000001_gene2197	1.858e-75	263.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1IUKS@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_4883402_3	502025.Hoch_2064	2.217e-141	468.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,42PQ6@68525|delta/epsilon subdivisions,2WJHR@28221|Deltaproteobacteria,2YV9V@29|Myxococcales	28221|Deltaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_4883402_4	866536.Belba_3010	8.83e-97	320.0	COG1960@1|root,COG1960@2|Bacteria,4NH3I@976|Bacteroidetes,47MEG@768503|Cytophagia	976|Bacteroidetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4885813_1	391625.PPSIR1_24749	6.061e-63	242.0	COG0437@1|root,COG0664@1|root,COG0437@2|Bacteria,COG0664@2|Bacteria,1QZTQ@1224|Proteobacteria,43CNM@68525|delta/epsilon subdivisions,2X2C7@28221|Deltaproteobacteria,2YX3F@29|Myxococcales	28221|Deltaproteobacteria	CT	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,cNMP_binding
CMS3_k127_4887372_7	502025.Hoch_2386	8.827e-14	81.0	COG0515@1|root,COG3063@1|root,COG0515@2|Bacteria,COG3063@2|Bacteria,1Q2R6@1224|Proteobacteria,433VB@68525|delta/epsilon subdivisions,2X3MY@28221|Deltaproteobacteria,2YWK6@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4887372_5	1192034.CAP_0782	4.067e-37	147.0	COG1595@1|root,COG1595@2|Bacteria,1Q6A3@1224|Proteobacteria,439KI@68525|delta/epsilon subdivisions,2X4XA@28221|Deltaproteobacteria,2YZSJ@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_4887372_0	1254432.SCE1572_06465	4.019e-129	455.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4887372_1	502025.Hoch_2589	9.347e-116	383.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_4887372_10	1242864.D187_006013	0.0001425	47.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_4887372_9	1144275.COCOR_01514	0.0001206	52.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YU2G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_4887372_3	1242864.D187_004040	9.202e-61	217.0	COG1502@1|root,COG1502@2|Bacteria,1RG9Z@1224|Proteobacteria,42RRF@68525|delta/epsilon subdivisions,2X6P0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
CMS3_k127_4887372_2	497964.CfE428DRAFT_4291	2.131e-110	375.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_4887372_4	290397.Adeh_0789	9.311e-46	169.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_4889977_0	502025.Hoch_3406	4.839e-123	401.0	COG1257@1|root,COG1257@2|Bacteria,1MXVE@1224|Proteobacteria,42R5Q@68525|delta/epsilon subdivisions,2WN6K@28221|Deltaproteobacteria,2YTT9@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
CMS3_k127_4889977_1	502025.Hoch_3405	1.712e-118	404.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Squalene phytoene synthase	hpnC	-	2.5.1.103,2.5.1.32,2.5.1.99,4.2.3.156	ko:K02291,ko:K21678,ko:K21679	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS3_k127_4889977_2	290397.Adeh_0730	2.788e-35	136.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2YU66@29|Myxococcales	28221|Deltaproteobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS3_k127_4890339_2	1192034.CAP_8371	9.622e-24	117.0	2ANWS@1|root,31DXD@2|Bacteria,1QB7T@1224|Proteobacteria,43E5G@68525|delta/epsilon subdivisions,2X98S@28221|Deltaproteobacteria,2Z2NC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4890339_1	1192034.CAP_8370	1.322e-58	223.0	COG4775@1|root,COG4775@2|Bacteria,1PBXZ@1224|Proteobacteria,433TZ@68525|delta/epsilon subdivisions,2X3G3@28221|Deltaproteobacteria,2YVY6@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
CMS3_k127_4890339_3	1502852.FG94_02976	4.457e-20	100.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4768Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HATPase_c,HisKA,Response_reg
CMS3_k127_4890339_0	1144275.COCOR_02951	1.921e-80	282.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
CMS3_k127_491339_28	391625.PPSIR1_19744	1.865e-09	59.0	COG0784@1|root,COG0784@2|Bacteria,1QAM7@1224|Proteobacteria,43563@68525|delta/epsilon subdivisions,2WZH3@28221|Deltaproteobacteria,2Z24X@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
CMS3_k127_491339_29	679926.Mpet_0531	2.536e-09	63.0	COG0835@1|root,arCOG02395@2157|Archaea,2XX4H@28890|Euryarchaeota	28890|Euryarchaeota	N	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS3_k127_491339_11	1499967.BAYZ01000004_gene4927	5.663e-97	345.0	COG0643@1|root,COG0643@2|Bacteria,2NQEX@2323|unclassified Bacteria	2|Bacteria	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K02487,ko:K03407,ko:K06596	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
CMS3_k127_491339_25	1121937.AUHJ01000011_gene2875	1.914e-24	121.0	COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria,46AA5@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_491339_24	1192034.CAP_6469	1.856e-27	130.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD
CMS3_k127_491339_2	502025.Hoch_4960	1.497e-248	788.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NHP@68525|delta/epsilon subdivisions,2X6U1@28221|Deltaproteobacteria,2Z35Z@29|Myxococcales	28221|Deltaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
CMS3_k127_491339_6	502025.Hoch_4961	1.034e-158	513.0	COG1520@1|root,COG1520@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_491339_12	768710.DesyoDRAFT_4626	2.296e-90	308.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,260DU@186807|Peptococcaceae	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS3_k127_491339_13	502025.Hoch_4963	4.525e-84	296.0	COG2856@1|root,COG2856@2|Bacteria,1Q3RV@1224|Proteobacteria,439JX@68525|delta/epsilon subdivisions,2X4WK@28221|Deltaproteobacteria,2YZRC@29|Myxococcales	28221|Deltaproteobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_491339_32	526225.Gobs_2286	9.825e-07	62.0	COG2755@1|root,COG2755@2|Bacteria,2IP29@201174|Actinobacteria	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_491339_0	570952.ATVH01000013_gene2807	1.063e-279	874.0	COG2909@1|root,COG2909@2|Bacteria,1RM5A@1224|Proteobacteria,2UB6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_491339_20	570952.ATVH01000013_gene2808	6.734e-43	160.0	COG2346@1|root,COG2346@2|Bacteria,1Q21Q@1224|Proteobacteria,2UHMU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_491339_18	1487953.JMKF01000061_gene4799	1.238e-50	192.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
CMS3_k127_491339_15	1192034.CAP_8408	1.642e-63	224.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,430PS@68525|delta/epsilon subdivisions,2WW31@28221|Deltaproteobacteria,2YVG0@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_491339_16	1192034.CAP_8408	8.931e-57	205.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,430PS@68525|delta/epsilon subdivisions,2WW31@28221|Deltaproteobacteria,2YVG0@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_491339_10	247634.GPB2148_3218	7.829e-103	356.0	COG2141@1|root,COG2141@2|Bacteria,1MXZH@1224|Proteobacteria,1RMB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate	rutA	GO:0003674,GO:0003824,GO:0004497,GO:0006139,GO:0006206,GO:0006208,GO:0006210,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0017144,GO:0019740,GO:0019859,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0052614,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.14.99.46	ko:K09018	ko00240,ko01100,map00240,map01100	-	R09936	RC02732	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_1123,iECUMN_1333.ECUMN_1195	Bac_luciferase
CMS3_k127_491339_22	391625.PPSIR1_40235	3.541e-35	137.0	COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_491339_7	391625.PPSIR1_40240	1.101e-136	448.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_491339_17	1173028.ANKO01000147_gene1272	4.118e-51	199.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.7	ko:K02342,ko:K02660	ko00230,ko00240,ko01100,ko02020,ko02025,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map02025,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044,ko03032,ko03400	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,MASE1,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS3_k127_491339_34	1266909.AUAG01000002_gene1312	0.0005175	51.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,1WZZ3@135613|Chromatiales	135613|Chromatiales	F	Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
CMS3_k127_491339_9	880073.Calab_1003	2.3e-104	358.0	COG1301@1|root,COG1301@2|Bacteria,2NP6X@2323|unclassified Bacteria	2|Bacteria	U	Sodium:dicarboxylate symporter family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
CMS3_k127_491339_5	1254432.SCE1572_03440	5.385e-166	548.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
CMS3_k127_491339_4	1237149.C900_00619	3.165e-187	604.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,47MRU@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
CMS3_k127_491339_23	391625.PPSIR1_41689	8.095e-30	136.0	2DDNF@1|root,2ZIP8@2|Bacteria,1P069@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_491339_8	472759.Nhal_0362	2.868e-132	437.0	COG2159@1|root,COG2159@2|Bacteria,1QDV1@1224|Proteobacteria,1RYCT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_491339_3	391625.PPSIR1_37349	1.849e-195	645.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_491339_30	43354.JOIJ01000008_gene3050	4.642e-08	60.0	COG0697@1|root,COG0697@2|Bacteria,2GMPU@201174|Actinobacteria,4E35E@85010|Pseudonocardiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_491339_27	443143.GM18_4346	4.861e-13	77.0	COG2346@1|root,COG2346@2|Bacteria,1Q6FD@1224|Proteobacteria,4331P@68525|delta/epsilon subdivisions,2WXI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_491339_21	1123053.AUDG01000041_gene846	5.174e-41	171.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,PPC,Peptidase_S8
CMS3_k127_491339_26	502025.Hoch_4107	2.921e-18	99.0	COG2755@1|root,COG2755@2|Bacteria,1NRYP@1224|Proteobacteria,437FJ@68525|delta/epsilon subdivisions,2X2N6@28221|Deltaproteobacteria,2YTXW@29|Myxococcales	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS3_k127_491339_1	886293.Sinac_1156	6.556e-266	858.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_4929122_0	314230.DSM3645_22204	0.0	1453.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2IY5P@203682|Planctomycetes	203682|Planctomycetes	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_4929122_3	1123279.ATUS01000003_gene506	7.363e-28	130.0	COG2234@1|root,COG2234@2|Bacteria,1R2N8@1224|Proteobacteria,1T5U9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4929122_1	448385.sce4861	8.169e-110	368.0	COG5337@1|root,COG5337@2|Bacteria,1Q378@1224|Proteobacteria,438XY@68525|delta/epsilon subdivisions,2X9VC@28221|Deltaproteobacteria,2YY5I@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_4929122_2	502025.Hoch_2386	1.893e-97	350.0	COG0515@1|root,COG3063@1|root,COG0515@2|Bacteria,COG3063@2|Bacteria,1Q2R6@1224|Proteobacteria,433VB@68525|delta/epsilon subdivisions,2X3MY@28221|Deltaproteobacteria,2YWK6@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4944847_1	105559.Nwat_1036	6.628e-131	428.0	COG1858@1|root,COG1858@2|Bacteria,1QW34@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4944847_5	156978.CIMIT_05985	5.894e-11	65.0	COG2835@1|root,COG2835@2|Bacteria,2I1D4@201174|Actinobacteria,22P53@1653|Corynebacteriaceae	201174|Actinobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
CMS3_k127_4944847_3	502025.Hoch_4498	2.494e-48	177.0	COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WS0J@28221|Deltaproteobacteria,2Z2ZP@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_4944847_2	502025.Hoch_4497	5.658e-121	398.0	COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,42R5A@68525|delta/epsilon subdivisions,2WN5N@28221|Deltaproteobacteria,2YUW3@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	catA	-	-	ko:K14696	-	-	-	-	ko00000,ko02000	2.A.4.6	-	-	Cation_efflux,ZT_dimer
CMS3_k127_4944847_4	502025.Hoch_5166	1.867e-16	94.0	COG1834@1|root,COG1834@2|Bacteria,1Q2GQ@1224|Proteobacteria,43839@68525|delta/epsilon subdivisions,2X3D8@28221|Deltaproteobacteria,2YVI2@29|Myxococcales	28221|Deltaproteobacteria	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS3_k127_4944847_0	448385.sce6911	1.01e-148	479.0	COG0010@1|root,COG0010@2|Bacteria,1Q4HC@1224|Proteobacteria,42Z7A@68525|delta/epsilon subdivisions,2WU9B@28221|Deltaproteobacteria,2YUSB@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_4944847_6	240015.ACP_1893	1.687e-05	55.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria,2JJAJ@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4953310_1	502025.Hoch_6531	2.033e-139	453.0	COG0531@1|root,COG0531@2|Bacteria,1R4IZ@1224|Proteobacteria,42MTQ@68525|delta/epsilon subdivisions,2WK39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
CMS3_k127_4953310_4	580332.Slit_1870	1.043e-17	89.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_4953310_3	1192034.CAP_7191	3.411e-27	127.0	2ANKP@1|root,31DJW@2|Bacteria,1QAVS@1224|Proteobacteria,435BV@68525|delta/epsilon subdivisions,2WZPD@28221|Deltaproteobacteria,2Z2GM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4953310_2	502025.Hoch_1985	7.184e-88	310.0	COG0515@1|root,COG0515@2|Bacteria,1Q35Q@1224|Proteobacteria,438W9@68525|delta/epsilon subdivisions,2X41T@28221|Deltaproteobacteria,2YXZI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4953310_5	1254432.SCE1572_26215	1.131e-09	70.0	COG4935@1|root,COG4935@2|Bacteria,1RK8D@1224|Proteobacteria,43C35@68525|delta/epsilon subdivisions,2X7DS@28221|Deltaproteobacteria,2YYHI@29|Myxococcales	28221|Deltaproteobacteria	O	Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PPC
CMS3_k127_4953310_6	658187.LDG_5898	6.244e-06	57.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1JCV3@118969|Legionellales	118969|Legionellales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LysM,RHS_repeat
CMS3_k127_4953310_0	42256.RradSPS_0409	1.673e-265	834.0	COG1297@1|root,COG1297@2|Bacteria,2I9UD@201174|Actinobacteria	201174|Actinobacteria	S	oligopeptide transporter opt family	opt	-	-	-	-	-	-	-	-	-	-	-	OPT
CMS3_k127_4953310_7	1201293.AKXQ01000003_gene2495	0.0008308	50.0	COG4188@1|root,COG4188@2|Bacteria,1QUVG@1224|Proteobacteria,1T22C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N,PAF-AH_p_II
CMS3_k127_4981277_1	1007105.PT7_2255	6.449e-52	188.0	COG3791@1|root,COG3791@2|Bacteria,1RD31@1224|Proteobacteria,2VS8R@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_4981277_0	290397.Adeh_3723	1.723e-202	657.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS3_k127_4981277_3	246197.MXAN_5953	5.922e-20	106.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2YWMC@29|Myxococcales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_4981277_2	502025.Hoch_1923	1.972e-31	126.0	COG0204@1|root,COG0204@2|Bacteria,1PZS9@1224|Proteobacteria,434JR@68525|delta/epsilon subdivisions,2WYX1@28221|Deltaproteobacteria,2Z0U7@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_4990276_4	713586.KB900536_gene2871	8.004e-11	63.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4990276_2	290397.Adeh_2888	3.074e-36	147.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4990276_1	1254432.SCE1572_30895	3.137e-45	168.0	COG1017@1|root,COG1017@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	VPA1107	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Globin
CMS3_k127_4990276_0	522306.CAP2UW1_2094	5.884e-180	587.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2VN25@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
CMS3_k127_5003868_2	502025.Hoch_0246	1.488e-89	308.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5003868_1	502025.Hoch_0245	3.921e-92	313.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	iAF1260.b1912,iAPECO1_1312.APECO1_954,iB21_1397.B21_01866,iBWG_1329.BWG_1721,iE2348C_1286.E2348C_2030,iEC042_1314.EC042_2073,iEC55989_1330.EC55989_2132,iECABU_c1320.ECABU_c21710,iECBD_1354.ECBD_1731,iECB_1328.ECB_01877,iECDH10B_1368.ECDH10B_2053,iECDH1ME8569_1439.ECDH1ME8569_1852,iECD_1391.ECD_01877,iECED1_1282.ECED1_2177,iECH74115_1262.ECH74115_2684,iECIAI1_1343.ECIAI1_1996,iECIAI39_1322.ECIAI39_1143,iECNA114_1301.ECNA114_2003,iECO103_1326.ECO103_2168,iECO111_1330.ECO111_2492,iECO26_1355.ECO26_2804,iECOK1_1307.ECOK1_2029,iECP_1309.ECP_1852,iECS88_1305.ECS88_1966,iECSF_1327.ECSF_1764,iECSP_1301.ECSP_2516,iECUMN_1333.ECUMN_2204,iECs_1301.ECs2650,iETEC_1333.ETEC_2020,iEcDH1_1363.EcDH1_1734,iEcE24377_1341.EcE24377A_2145,iEcHS_1320.EcHS_A2010,iEcSMS35_1347.EcSMS35_1271,iEcolC_1368.EcolC_1727,iG2583_1286.G2583_2363,iJO1366.b1912,iJR904.b1912,iLF82_1304.LF82_1635,iNRG857_1313.NRG857_09550,iSDY_1059.SDY_1106,iSSON_1240.SSON_1206,iSbBS512_1146.SbBS512_E1039,iUMN146_1321.UM146_07620,iUMNK88_1353.UMNK88_2386,iUTI89_1310.UTI89_C2113,iY75_1357.Y75_RS10025,iYL1228.KPN_02410,iZ_1308.Z3000,ic_1306.c2325	CDP-OH_P_transf
CMS3_k127_5003868_0	502025.Hoch_3674	8.915e-100	362.0	COG2010@1|root,COG4733@1|root,COG2010@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,PSCyt1,SLH,WD40,fn3
CMS3_k127_5003868_4	82654.Pse7367_0716	1.364e-42	167.0	COG3264@1|root,COG3264@2|Bacteria,1G2UD@1117|Cyanobacteria,1H8A1@1150|Oscillatoriales	1117|Cyanobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	DEP,MS_channel
CMS3_k127_5003868_3	502025.Hoch_0219	2.941e-67	231.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2YWRT@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
CMS3_k127_5007449_1	391625.PPSIR1_09505	7.589e-32	132.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,42QZE@68525|delta/epsilon subdivisions,2WS8W@28221|Deltaproteobacteria,2YW5B@29|Myxococcales	28221|Deltaproteobacteria	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS3_k127_5007449_0	391625.PPSIR1_09510	6.617e-100	351.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
CMS3_k127_5007449_2	1485545.JQLW01000010_gene1653	6.818e-13	83.0	COG4188@1|root,COG4188@2|Bacteria,1QUVG@1224|Proteobacteria	1224|Proteobacteria	S	COG1073 hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N
CMS3_k127_5010147_5	502025.Hoch_3855	1.755e-19	93.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS3_k127_5010147_7	1232429.CBLL010000067_gene1668	5.864e-16	80.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,1WA8F@1268|Micrococcaceae	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
CMS3_k127_5010147_0	502025.Hoch_6193	2.537e-219	710.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2YU1F@29|Myxococcales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS3_k127_5010147_6	502025.Hoch_3852	5.663e-18	93.0	COG1550@1|root,COG1550@2|Bacteria,1NBXZ@1224|Proteobacteria,42W9E@68525|delta/epsilon subdivisions,2WRK0@28221|Deltaproteobacteria,2YW04@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
CMS3_k127_5010147_4	502025.Hoch_3851	1.281e-21	109.0	COG0858@1|root,COG0858@2|Bacteria	2|Bacteria	J	rRNA processing	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS3_k127_5010147_3	398767.Glov_1671	1.593e-58	220.0	COG0618@1|root,COG0618@2|Bacteria,1RAUQ@1224|Proteobacteria,42RKG@68525|delta/epsilon subdivisions,2WN0X@28221|Deltaproteobacteria,43TAU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_5010147_1	502025.Hoch_3850	6.563e-83	287.0	COG2133@1|root,COG2133@2|Bacteria,1PEHH@1224|Proteobacteria,437W5@68525|delta/epsilon subdivisions,2X35P@28221|Deltaproteobacteria,2YUDG@29|Myxococcales	28221|Deltaproteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_5010147_2	1439940.BAY1663_01540	6.872e-69	243.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
CMS3_k127_5012591_0	502025.Hoch_6085	2.703e-31	125.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_6085|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5018575_1	502025.Hoch_6008	2.68e-37	152.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2YVHS@29|Myxococcales	28221|Deltaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS3_k127_5018575_0	502025.Hoch_6009	2.61e-245	771.0	COG0773@1|root,COG1246@1|root,COG0773@2|Bacteria,COG1246@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2YU74@29|Myxococcales	28221|Deltaproteobacteria	M	Mur ligase family, catalytic domain	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_5036728_1	1192034.CAP_0175	1.709e-28	125.0	COG0457@1|root,COG0457@2|Bacteria,1P0DI@1224|Proteobacteria,431RN@68525|delta/epsilon subdivisions,2WWCP@28221|Deltaproteobacteria,2Z3IU@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5036728_0	1192034.CAP_7954	2.167e-95	335.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CMS3_k127_5037074_0	246197.MXAN_6997	4.003e-113	398.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1NH16@1224|Proteobacteria	1224|Proteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_5037074_1	404589.Anae109_0870	0.00025	45.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
CMS3_k127_5041830_4	502025.Hoch_2541	9.626e-105	346.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YWIW@29|Myxococcales	28221|Deltaproteobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
CMS3_k127_5041830_9	710687.KI912270_gene1421	5.612e-08	65.0	COG4402@1|root,COG4402@2|Bacteria,2I90K@201174|Actinobacteria,236XA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_5041830_3	502025.Hoch_5811	4.165e-109	373.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5041830_5	502025.Hoch_3859	6.234e-70	256.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2WNND@28221|Deltaproteobacteria,2Z2YW@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS3_k127_5041830_7	404589.Anae109_0480	3.394e-53	213.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2YV59@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS3_k127_5041830_1	502025.Hoch_3862	4.153e-255	797.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS3_k127_5041830_2	502025.Hoch_3863	5.409e-147	490.0	COG3107@1|root,COG3107@2|Bacteria,1R0ND@1224|Proteobacteria,42NIT@68525|delta/epsilon subdivisions,2WMMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidoglycan biosynthetic process	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_5041830_6	502025.Hoch_3865	4.651e-63	229.0	COG0457@1|root,COG3824@1|root,COG0457@2|Bacteria,COG3824@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria,2YW72@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
CMS3_k127_5041830_0	502025.Hoch_4061	0.0	1771.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2YU4G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_5052845_3	886293.Sinac_3407	4.242e-31	125.0	COG0789@1|root,COG0789@2|Bacteria,2J3U2@203682|Planctomycetes	203682|Planctomycetes	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_5052845_2	1192034.CAP_3813	2.144e-33	150.0	COG3055@1|root,COG5640@1|root,COG3055@2|Bacteria,COG5640@2|Bacteria,1QY1Z@1224|Proteobacteria,43283@68525|delta/epsilon subdivisions,2WY98@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_5052845_1	502025.Hoch_1795	2.008e-121	398.0	COG2159@1|root,COG2159@2|Bacteria,1Q4Y5@1224|Proteobacteria,4304H@68525|delta/epsilon subdivisions,2WVAR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_5052845_0	502025.Hoch_5231	6.522e-158	511.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YYE4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_5059155_12	502025.Hoch_4111	2.042e-05	46.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2YUGE@29|Myxococcales	28221|Deltaproteobacteria	J	Elongation factor G, domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_5059155_1	502025.Hoch_4112	1.348e-154	496.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2YVCP@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS3_k127_5059155_10	502025.Hoch_4115	3.592e-20	93.0	COG2146@1|root,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	ko:K14952	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	Lactamase_B_3,Rieske
CMS3_k127_5059155_6	502025.Hoch_4117	7.09e-58	213.0	COG2025@1|root,COG2025@2|Bacteria	2|Bacteria	C	fatty acid beta-oxidation using acyl-CoA dehydrogenase	etfA-1	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS3_k127_5059155_9	502025.Hoch_4118	1.354e-20	107.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	eftB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_5059155_2	502025.Hoch_4119	3.654e-118	395.0	COG0045@1|root,COG0045@2|Bacteria	2|Bacteria	C	succinate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS3_k127_5059155_7	2074.JNYD01000010_gene1031	3.257e-55	205.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_5059155_3	502025.Hoch_2407	2.263e-104	351.0	COG0617@1|root,COG0617@2|Bacteria,1P341@1224|Proteobacteria,42P8G@68525|delta/epsilon subdivisions,2WJYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Metal-dependent phosphohydrolase, HD	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS3_k127_5059155_0	502025.Hoch_2406	0.0	1030.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria,1MWRF@1224|Proteobacteria,42UA0@68525|delta/epsilon subdivisions,2WS4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
CMS3_k127_5059155_4	502025.Hoch_2401	3.324e-81	287.0	2DYJ3@1|root,34A1W@2|Bacteria,1PDJB@1224|Proteobacteria,435GY@68525|delta/epsilon subdivisions,2X99N@28221|Deltaproteobacteria,2Z2SE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CMS3_k127_5067452_0	502025.Hoch_4657	1.472e-140	456.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2YVDN@29|Myxococcales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS3_k127_5067452_4	502025.Hoch_5401	1.537e-54	200.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS3_k127_5067452_2	502025.Hoch_5811	7.161e-107	366.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5067452_5	1217648.F933_01804	1.018e-36	150.0	COG5595@1|root,COG5595@2|Bacteria,1NDR3@1224|Proteobacteria,1RRXG@1236|Gammaproteobacteria,3NQ2W@468|Moraxellaceae	1236|Gammaproteobacteria	S	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2310
CMS3_k127_5067452_3	1144275.COCOR_02951	3.248e-61	233.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
CMS3_k127_5067452_7	857087.Metme_0486	3.357e-31	135.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
CMS3_k127_5067452_6	269798.CHU_2379	1.047e-32	136.0	COG0726@1|root,COG3405@1|root,COG0726@2|Bacteria,COG3405@2|Bacteria,4NUMA@976|Bacteroidetes,47UIR@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 11	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_11
CMS3_k127_5067452_1	1242864.D187_002403	2.816e-115	393.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X7AD@28221|Deltaproteobacteria,2YUMR@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_5067452_8	502025.Hoch_5174	4.374e-31	129.0	2E1HF@1|root,32WVJ@2|Bacteria,1NHTX@1224|Proteobacteria,42X6V@68525|delta/epsilon subdivisions,2WSSD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5087706_1	886293.Sinac_1156	3.77e-209	691.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5087706_5	448385.sce1948	1.095e-111	384.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
CMS3_k127_5087706_9	1121937.AUHJ01000004_gene1135	1.141e-55	206.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,467CH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Na -dependent transporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS3_k127_5087706_3	314230.DSM3645_16830	2.361e-155	499.0	COG0520@1|root,COG0520@2|Bacteria,2IX8C@203682|Planctomycetes	203682|Planctomycetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_5087706_2	886293.Sinac_1156	6.103e-176	588.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5087706_12	215803.DB30_5017	7.721e-10	68.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,4345S@68525|delta/epsilon subdivisions,2X1UG@28221|Deltaproteobacteria,2YTU5@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
CMS3_k127_5087706_6	1121935.AQXX01000064_gene3298	2.821e-95	331.0	COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,1RRAQ@1236|Gammaproteobacteria,1XKF1@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_5087706_7	526225.Gobs_4316	1.624e-85	295.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4EU5K@85013|Frankiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_5087706_8	1192034.CAP_0893	3.943e-78	271.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CMS3_k127_5087706_11	502025.Hoch_6453	6.708e-20	99.0	28W5H@1|root,2ZI6A@2|Bacteria,1QBFX@1224|Proteobacteria,435GD@68525|delta/epsilon subdivisions,2WZTW@28221|Deltaproteobacteria,2Z2QX@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS3_k127_5087706_4	502025.Hoch_5171	3.981e-118	415.0	COG4775@1|root,COG4775@2|Bacteria,1Q2CZ@1224|Proteobacteria,437ZA@68525|delta/epsilon subdivisions,2X399@28221|Deltaproteobacteria,2YUX9@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_5087706_10	926550.CLDAP_01280	2.754e-55	220.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5087706_0	502025.Hoch_3879	9.228e-220	694.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2YUJ3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS3_k127_5091798_0	502025.Hoch_3831	1.166e-178	574.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	pp2c12	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
CMS3_k127_5091798_1	1242864.D187_003261	1.575e-16	89.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
CMS3_k127_5099234_1	698761.RTCIAT899_CH14615	4.651e-12	78.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,4BCCW@82115|Rhizobiaceae	28211|Alphaproteobacteria	U	Biopolymer transport protein	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
CMS3_k127_5099234_0	391625.PPSIR1_27668	1.108e-119	410.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,42ZYH@68525|delta/epsilon subdivisions,2WVEZ@28221|Deltaproteobacteria,2YZS1@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CBM_20,DUF3459
CMS3_k127_5099539_1	502025.Hoch_2509	6.073e-99	354.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5099539_0	502025.Hoch_2508	6.543e-195	622.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5099539_10	682795.AciX8_1677	3.881e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,3Y404@57723|Acidobacteria,2JHJ1@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5099539_3	945550.VISI1226_10607	4.358e-54	211.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XSRH@135623|Vibrionales	135623|Vibrionales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_2
CMS3_k127_5099539_9	502025.Hoch_5563	9.825e-14	84.0	COG5184@1|root,COG5184@2|Bacteria,1QF75@1224|Proteobacteria,434P4@68525|delta/epsilon subdivisions,2WZ0D@28221|Deltaproteobacteria,2Z125@29|Myxococcales	28221|Deltaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5099539_8	404589.Anae109_2070	2.583e-31	142.0	2ANHB@1|root,31DG4@2|Bacteria,1QAPZ@1224|Proteobacteria,43582@68525|delta/epsilon subdivisions,2WZJ2@28221|Deltaproteobacteria,2Z28Y@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5099539_6	483219.LILAB_30350	4.675e-35	151.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
CMS3_k127_5099539_4	483219.LILAB_29355	7.807e-39	153.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,2YV02@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_5099539_2	1242864.D187_006890	1.007e-70	261.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_5099539_7	404589.Anae109_4372	9.814e-35	141.0	COG2204@1|root,COG3437@1|root,COG3852@1|root,COG2204@2|Bacteria,COG3437@2|Bacteria,COG3852@2|Bacteria,1QUN9@1224|Proteobacteria,43CD3@68525|delta/epsilon subdivisions,2X7NY@28221|Deltaproteobacteria,2Z2WN@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg
CMS3_k127_5099539_5	502025.Hoch_2507	2.39e-36	153.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_5128945_8	556268.OFAG_01428	1.241e-72	263.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,473B4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	bbsI	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS3_k127_5128945_13	1423724.BAMM01000011_gene1263	1.05e-08	67.0	COG0681@1|root,COG0681@2|Bacteria,1V2RW@1239|Firmicutes,4I0WP@91061|Bacilli,3FCBK@33958|Lactobacillaceae	91061|Bacilli	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS3_k127_5128945_9	502025.Hoch_4105	1.303e-37	150.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,2YVSW@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS3_k127_5128945_3	502025.Hoch_4104	7.557e-119	386.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2YUEF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS3_k127_5128945_11	502025.Hoch_4103	8.713e-18	85.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2X2JA@28221|Deltaproteobacteria,2YW1J@29|Myxococcales	28221|Deltaproteobacteria	H	Thiamine biosynthesis	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_5128945_4	502025.Hoch_4102	9.263e-112	367.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria,2Z1HI@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_5128945_5	502025.Hoch_1885	1.143e-108	363.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,2YZJS@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS3_k127_5128945_7	502025.Hoch_1886	4.82e-94	332.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2YV04@29|Myxococcales	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_5128945_2	502025.Hoch_1888	4.43e-168	543.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WNNQ@28221|Deltaproteobacteria,2YUZI@29|Myxococcales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_5128945_12	1435356.Y013_11250	8.264e-13	81.0	COG3693@1|root,COG3693@2|Bacteria,2I9V3@201174|Actinobacteria,4G8R5@85025|Nocardiaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS3_k127_5128945_0	886293.Sinac_1156	1.963e-286	922.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5128945_1	984262.SGRA_3613	2.367e-185	591.0	COG0189@1|root,COG0189@2|Bacteria,4NH5R@976|Bacteroidetes	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5128945_6	691883.XP_009496844.1	1.841e-103	363.0	COG3608@1|root,2QUCF@2759|Eukaryota,39WH0@33154|Opisthokonta	33154|Opisthokonta	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,HutD
CMS3_k127_5128945_10	502025.Hoch_1889	8.802e-36	143.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,2YW6X@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS3_k127_5137705_14	5664.LmjF.34.3190	2.281e-06	53.0	COG0451@1|root,KOG1502@2759|Eukaryota,3XRRF@5653|Kinetoplastida	5653|Kinetoplastida	V	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_5137705_3	1047013.AQSP01000142_gene242	7.852e-128	436.0	COG2511@1|root,COG2511@2|Bacteria	2|Bacteria	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
CMS3_k127_5137705_2	1499683.CCFF01000013_gene324	1.634e-190	636.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS3_k127_5137705_0	502025.Hoch_6655	4.707e-278	863.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2YUA8@29|Myxococcales	28221|Deltaproteobacteria	J	glutaminyl-tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
CMS3_k127_5137705_10	221360.RS9917_07005	1.332e-19	96.0	COG2062@1|root,COG2062@2|Bacteria,1G6QD@1117|Cyanobacteria,1H1C1@1129|Synechococcus	1117|Cyanobacteria	T	Phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS3_k127_5137705_1	1254432.SCE1572_50885	7.264e-232	754.0	COG0515@1|root,COG2909@1|root,COG0515@2|Bacteria,COG2909@2|Bacteria,1QA6R@1224|Proteobacteria,4393M@68525|delta/epsilon subdivisions,2X49J@28221|Deltaproteobacteria,2YYJG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5137705_5	1192034.CAP_0196	6.862e-101	340.0	COG3503@1|root,COG3503@2|Bacteria,1QQ9D@1224|Proteobacteria,431ME@68525|delta/epsilon subdivisions,2WWTB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS3_k127_5137705_12	525904.Tter_2790	3.189e-08	58.0	2CA4F@1|root,33DCB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5137705_13	391625.PPSIR1_23759	1.316e-06	61.0	COG5164@1|root,COG5164@2|Bacteria,1NIMU@1224|Proteobacteria,43309@68525|delta/epsilon subdivisions,2WY60@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5137705_6	502025.Hoch_4785	1.142e-54	205.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YV6N@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_5137705_11	485917.Phep_3786	1.663e-11	75.0	COG3568@1|root,COG3568@2|Bacteria,4NPXM@976|Bacteroidetes,1IXS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_5137705_7	1123053.AUDG01000037_gene298	8.365e-25	122.0	COG0739@1|root,COG1680@1|root,COG0739@2|Bacteria,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4185,GBS_Bsp-like,OapA,Peptidase_M23
CMS3_k127_5137705_8	290397.Adeh_1015	3.086e-20	90.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,42NVI@68525|delta/epsilon subdivisions,2WJTD@28221|Deltaproteobacteria,2YTYS@29|Myxococcales	28221|Deltaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_5143537_2	502025.Hoch_3601	3.636e-28	115.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2X5NA@28221|Deltaproteobacteria,2Z36H@29|Myxococcales	28221|Deltaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_5143537_1	502025.Hoch_5812	1.266e-34	147.0	COG4577@1|root,COG4577@2|Bacteria,1R55P@1224|Proteobacteria,42RUF@68525|delta/epsilon subdivisions,2WNT1@28221|Deltaproteobacteria,2Z1MN@29|Myxococcales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
CMS3_k127_5143537_0	502025.Hoch_5813	2.405e-93	309.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,42P3A@68525|delta/epsilon subdivisions,2WIJU@28221|Deltaproteobacteria,2YYR4@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
CMS3_k127_5144646_5	448385.sce9236	1.287e-85	301.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
CMS3_k127_5144646_3	448385.sce9236	2.722e-132	447.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
CMS3_k127_5144646_2	1192034.CAP_4130	5.85e-135	442.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
CMS3_k127_5144646_1	502025.Hoch_6072	2.695e-157	507.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2YZWP@29|Myxococcales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS3_k127_5144646_9	935567.JAES01000002_gene720	7.006e-39	148.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S69Q@1236|Gammaproteobacteria,1X8MY@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_5144646_11	1338011.BD94_2338	1.263e-06	58.0	COG3637@1|root,COG3637@2|Bacteria,4NVT2@976|Bacteroidetes,1I8VN@117743|Flavobacteriia,34RGW@308865|Elizabethkingia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS3_k127_5144646_4	1192034.CAP_4231	4.723e-115	394.0	COG0793@1|root,COG3485@1|root,COG0793@2|Bacteria,COG3485@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_5144646_7	502025.Hoch_5186	2.847e-80	278.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
CMS3_k127_5144646_10	1123228.AUIH01000001_gene1208	9.793e-19	89.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,1S8ZV@1236|Gammaproteobacteria,1XKGB@135619|Oceanospirillales	135619|Oceanospirillales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS3_k127_5144646_6	483219.LILAB_03760	1.066e-80	286.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2Z2R6@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_5144646_8	1121451.DESAM_21375	1.211e-62	245.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2M9X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
CMS3_k127_5144646_0	246197.MXAN_0988	0.0	1439.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
CMS3_k127_5154197_0	378806.STAUR_0709	4.408e-128	434.0	COG0457@1|root,COG0515@1|root,COG3267@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3267@2|Bacteria,1MV1P@1224|Proteobacteria,43C0J@68525|delta/epsilon subdivisions,2X7B7@28221|Deltaproteobacteria,2YUMJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5154197_1	1192034.CAP_4200	5.632e-107	366.0	COG3537@1|root,COG3537@2|Bacteria,1MXCY@1224|Proteobacteria,43BAT@68525|delta/epsilon subdivisions,2X6PZ@28221|Deltaproteobacteria,2YX4I@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
CMS3_k127_5158769_13	1121405.dsmv_0802	2.124e-17	83.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2WRUT@28221|Deltaproteobacteria,2MNXP@213118|Desulfobacterales	28221|Deltaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS3_k127_5158769_8	357808.RoseRS_2516	1.357e-41	167.0	COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Methionine synthase, vitamin-B12 independent	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_5158769_12	1223544.GSI01S_05_00660	8.385e-29	129.0	COG3315@1|root,COG3315@2|Bacteria,2GN89@201174|Actinobacteria,4GFDQ@85026|Gordoniaceae	201174|Actinobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_5158769_10	502025.Hoch_4820	3.027e-32	133.0	COG0484@1|root,COG0484@2|Bacteria,1NQ7Z@1224|Proteobacteria	1224|Proteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS3_k127_5158769_9	1254432.SCE1572_42340	4.542e-33	136.0	COG3215@1|root,COG3215@2|Bacteria,1QZU1@1224|Proteobacteria,43CP3@68525|delta/epsilon subdivisions,2X7WD@28221|Deltaproteobacteria,2Z2BM@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_5158769_1	269799.Gmet_3192	2.103e-150	493.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS3_k127_5158769_7	502025.Hoch_5497	7.532e-47	187.0	COG0720@1|root,COG0720@2|Bacteria,1N10D@1224|Proteobacteria,433I0@68525|delta/epsilon subdivisions,2WXNU@28221|Deltaproteobacteria,2Z1HK@29|Myxococcales	28221|Deltaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_5158769_2	1144275.COCOR_03797	1.037e-133	464.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,438M3@68525|delta/epsilon subdivisions,2X1ZS@28221|Deltaproteobacteria,2YX8A@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
CMS3_k127_5158769_0	502025.Hoch_5496	5.397e-231	731.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YTZI@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
CMS3_k127_5158769_6	1144275.COCOR_04135	5.702e-50	194.0	COG0664@1|root,COG3266@1|root,COG0664@2|Bacteria,COG3266@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YXD4@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_5158769_3	502025.Hoch_5494	2.976e-77	264.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,430W9@68525|delta/epsilon subdivisions,2WW2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
CMS3_k127_5158769_4	765869.BDW_13720	4.123e-65	235.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2MSNM@213481|Bdellovibrionales,2X6YI@28221|Deltaproteobacteria	213481|Bdellovibrionales	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Pkinase,PocR,Sigma54_activat
CMS3_k127_5168820_4	69395.JQLZ01000007_gene1748	2.287e-05	56.0	COG3712@1|root,COG3712@2|Bacteria,1NR9D@1224|Proteobacteria,2UP72@28211|Alphaproteobacteria,2KI6J@204458|Caulobacterales	204458|Caulobacterales	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS3_k127_5168820_3	391625.PPSIR1_35672	1.809e-32	147.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD
CMS3_k127_5168820_1	570952.ATVH01000015_gene1569	4.539e-116	385.0	COG3616@1|root,COG3616@2|Bacteria,1N2SF@1224|Proteobacteria,2VFY5@28211|Alphaproteobacteria,2JRKP@204441|Rhodospirillales	204441|Rhodospirillales	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS3_k127_5168820_2	192875.XP_004363575.1	1.605e-46	191.0	2EQBW@1|root,2STD3@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5168820_0	756272.Plabr_2494	7.937e-153	492.0	COG0446@1|root,COG0446@2|Bacteria,2IXBK@203682|Planctomycetes	203682|Planctomycetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_5185286_0	1278073.MYSTI_04946	9.235e-121	402.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2YXPT@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS3_k127_5185286_2	1177181.T9A_01961	1.653e-39	150.0	COG2259@1|root,COG2259@2|Bacteria,1MZC7@1224|Proteobacteria,1SANJ@1236|Gammaproteobacteria,1XPJK@135619|Oceanospirillales	135619|Oceanospirillales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS3_k127_5185286_1	502025.Hoch_3477	1.409e-52	191.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,42RN4@68525|delta/epsilon subdivisions,2WP37@28221|Deltaproteobacteria,2YVD3@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS3_k127_5192807_0	502025.Hoch_3647	3.172e-206	644.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_5192807_3	502025.Hoch_3211	5.349e-118	403.0	2ARW7@1|root,31H81@2|Bacteria,1QEXJ@1224|Proteobacteria,439J5@68525|delta/epsilon subdivisions,2X4VQ@28221|Deltaproteobacteria,2YZPU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5192807_6	215803.DB30_4708	2.806e-45	186.0	COG0388@1|root,COG0388@2|Bacteria,1Q1Q0@1224|Proteobacteria,439D4@68525|delta/epsilon subdivisions,2X4MT@28221|Deltaproteobacteria,2YZ9K@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS3_k127_5192807_5	861299.J421_3449	1.51e-75	263.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_5192807_7	321332.CYB_2397	1.657e-36	147.0	COG1994@1|root,COG1994@2|Bacteria,1G5AD@1117|Cyanobacteria,1H0JV@1129|Synechococcus	1117|Cyanobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
CMS3_k127_5192807_10	391625.PPSIR1_16775	5.044e-15	88.0	COG3921@1|root,COG3921@2|Bacteria,1QASS@1224|Proteobacteria,4359Z@68525|delta/epsilon subdivisions,2WZM2@28221|Deltaproteobacteria,2Z2CT@29|Myxococcales	28221|Deltaproteobacteria	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
CMS3_k127_5192807_2	1382356.JQMP01000001_gene901	3.694e-121	407.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
CMS3_k127_5192807_1	502025.Hoch_4723	1.652e-201	656.0	COG4783@1|root,COG4783@2|Bacteria,1R0NF@1224|Proteobacteria,43CZ3@68525|delta/epsilon subdivisions,2X87B@28221|Deltaproteobacteria,2Z3MH@29|Myxococcales	28221|Deltaproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5192807_8	502025.Hoch_4722	2.631e-36	142.0	COG3215@1|root,COG3215@2|Bacteria,1Q2S4@1224|Proteobacteria,43266@68525|delta/epsilon subdivisions,2WXR8@28221|Deltaproteobacteria,2YVFJ@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
CMS3_k127_5192807_4	502025.Hoch_4721	2.267e-90	306.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2YVVU@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_5198805_11	502025.Hoch_5066	5.497e-73	251.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YUHH@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS3_k127_5198805_5	502025.Hoch_5067	1.28e-118	392.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YV9N@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CMS3_k127_5198805_12	502025.Hoch_5069	3.891e-66	248.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5198805_7	502025.Hoch_5070	1.86e-102	339.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42PZ9@68525|delta/epsilon subdivisions,2WM8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5198805_13	502025.Hoch_5071	3.712e-65	226.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS3_k127_5198805_9	502025.Hoch_5072	3.273e-76	265.0	COG0726@1|root,COG0726@2|Bacteria,1PEGX@1224|Proteobacteria,437HX@68525|delta/epsilon subdivisions,2WTK9@28221|Deltaproteobacteria,2Z1M4@29|Myxococcales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_5198805_6	502025.Hoch_4839	2.909e-117	387.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,42SUP@68525|delta/epsilon subdivisions,2WPBD@28221|Deltaproteobacteria,2YU07@29|Myxococcales	28221|Deltaproteobacteria	E	N-succinyltransferase beta subunit	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
CMS3_k127_5198805_2	404589.Anae109_1105	1.483e-153	499.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5198805_10	502025.Hoch_4842	4.177e-75	280.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,Wzy_C
CMS3_k127_5198805_1	502025.Hoch_4243	8.133e-170	543.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,43DT3@68525|delta/epsilon subdivisions,2WYT8@28221|Deltaproteobacteria,2Z0JK@29|Myxococcales	28221|Deltaproteobacteria	C	Radical SAM superfamily	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Radical_SAM
CMS3_k127_5198805_4	502025.Hoch_4244	1.665e-120	395.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,42RV7@68525|delta/epsilon subdivisions,2WNZT@28221|Deltaproteobacteria,2YZ8A@29|Myxococcales	28221|Deltaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
CMS3_k127_5198805_18	648996.Theam_1762	0.0005024	51.0	COG0750@1|root,COG0750@2|Bacteria,2G3QY@200783|Aquificae	200783|Aquificae	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS3_k127_5198805_3	502025.Hoch_6704	2.723e-133	434.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_6704|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5198805_8	502025.Hoch_6705	5.138e-90	316.0	COG4913@1|root,COG4913@2|Bacteria	2|Bacteria	D	Putative exonuclease SbcCD, C subunit	yacH	-	-	-	-	-	-	-	-	-	-	-	DUF3300,SbcCD_C,TMP_2,YqaJ
CMS3_k127_5198805_0	448385.sce3068	1.556e-195	630.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42PEY@68525|delta/epsilon subdivisions,2WJJ3@28221|Deltaproteobacteria,2YUIV@29|Myxococcales	28221|Deltaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_5198805_14	1278073.MYSTI_02671	6.905e-56	218.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_5199006_0	502025.Hoch_0008	4.183e-152	497.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2YUN7@29|Myxococcales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS3_k127_5199006_2	502025.Hoch_0009	3.133e-33	136.0	COG1801@1|root,COG1801@2|Bacteria,1N66P@1224|Proteobacteria,42U3V@68525|delta/epsilon subdivisions,2WQYP@28221|Deltaproteobacteria,2Z2V4@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_5199006_1	502025.Hoch_0010	7.412e-69	238.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2YTW3@29|Myxococcales	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS3_k127_5207993_3	765911.Thivi_2846	4.344e-129	424.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,1S0QY@1236|Gammaproteobacteria,1WXB1@135613|Chromatiales	135613|Chromatiales	J	S1, RNA binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_5207993_8	502025.Hoch_3199	1.323e-19	93.0	2AQ5Z@1|root,31FBG@2|Bacteria,1PCFM@1224|Proteobacteria,43E4N@68525|delta/epsilon subdivisions,2X980@28221|Deltaproteobacteria,2Z2HX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5207993_4	502025.Hoch_5322	1.293e-108	372.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TPR_12
CMS3_k127_5207993_2	391625.PPSIR1_05538	1.426e-155	523.0	2BKKY@1|root,32F29@2|Bacteria,1QTPH@1224|Proteobacteria,438GE@68525|delta/epsilon subdivisions,2X3R7@28221|Deltaproteobacteria,2YWWS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5207993_7	1242864.D187_002107	3.693e-33	148.0	COG1525@1|root,COG1525@2|Bacteria,1Q1YZ@1224|Proteobacteria,437KZ@68525|delta/epsilon subdivisions,2X2V2@28221|Deltaproteobacteria,2YW2G@29|Myxococcales	28221|Deltaproteobacteria	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS3_k127_5207993_6	483219.LILAB_05955	8.308e-92	323.0	2C5G2@1|root,2ZXM4@2|Bacteria,1P4E3@1224|Proteobacteria,43C5T@68525|delta/epsilon subdivisions,2X7G1@28221|Deltaproteobacteria,2YZYE@29|Myxococcales	28221|Deltaproteobacteria	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CMS3_k127_5207993_5	391625.PPSIR1_05553	3.937e-103	351.0	COG1525@1|root,COG1525@2|Bacteria,1P7XF@1224|Proteobacteria,432GM@68525|delta/epsilon subdivisions,2WY1F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
CMS3_k127_5207993_0	502025.Hoch_2126	5.918e-244	765.0	COG2866@1|root,COG2866@2|Bacteria,1R586@1224|Proteobacteria,433ZT@68525|delta/epsilon subdivisions,2X4AT@28221|Deltaproteobacteria,2YYMP@29|Myxococcales	28221|Deltaproteobacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_5207993_1	502025.Hoch_4143	3.063e-168	575.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_7,TPR_8
CMS3_k127_5241432_4	1254432.SCE1572_10985	5.365e-46	168.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,42RF8@68525|delta/epsilon subdivisions,2WNSP@28221|Deltaproteobacteria,2YVG6@29|Myxococcales	28221|Deltaproteobacteria	T	Chemotaxis protein CheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_5241432_10	404380.Gbem_0749	4.723e-27	118.0	COG2203@1|root,COG2203@2|Bacteria,1RJ35@1224|Proteobacteria,42T0K@68525|delta/epsilon subdivisions,2WPIM@28221|Deltaproteobacteria,43T60@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3
CMS3_k127_5241432_1	243231.GSU2214	5.978e-85	314.0	COG2201@1|root,COG2201@2|Bacteria,1R5IM@1224|Proteobacteria,42Q4X@68525|delta/epsilon subdivisions,2WMDB@28221|Deltaproteobacteria,43T38@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB40H-1	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS3_k127_5241432_2	215803.DB30_0056	4.105e-81	293.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,2YUW4@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS3_k127_5241432_9	1144275.COCOR_02642	4.689e-27	128.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CMS3_k127_5241432_7	1232410.KI421413_gene810	2.041e-29	127.0	COG0745@1|root,COG0745@2|Bacteria,1NV0N@1224|Proteobacteria,42ZH3@68525|delta/epsilon subdivisions,2WUW0@28221|Deltaproteobacteria,43UQG@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,zinc_ribbon_4
CMS3_k127_5241432_6	690850.Desaf_2727	2.371e-34	145.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WNT6@28221|Deltaproteobacteria,2MAZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS3_k127_5241432_8	1232410.KI421413_gene813	1.715e-28	134.0	COG0835@1|root,COG0835@2|Bacteria,1RG4A@1224|Proteobacteria,43AIK@68525|delta/epsilon subdivisions,2X5YT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	cheW64H-1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS3_k127_5241432_0	391625.PPSIR1_08966	5.005e-189	614.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2YU8D@29|Myxococcales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric domain	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS3_k127_5241432_5	215803.DB30_0061	8.347e-35	136.0	COG0745@1|root,COG0745@2|Bacteria,1N1TA@1224|Proteobacteria,42V03@68525|delta/epsilon subdivisions,2WPZR@28221|Deltaproteobacteria,2YVV2@29|Myxococcales	28221|Deltaproteobacteria	T	Chemotaxis protein CheY	cheY40H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_5241432_11	582515.KR51_00034220	2.815e-19	104.0	COG1750@1|root,COG1750@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Lon_C,SdrD_B
CMS3_k127_5241432_12	502025.Hoch_0246	2.003e-14	85.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5241432_13	502025.Hoch_0246	8.328e-11	74.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5241432_3	502025.Hoch_0246	2.501e-55	220.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5241432_14	710111.FraQA3DRAFT_0235	2.93e-06	53.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
CMS3_k127_525800_5	502025.Hoch_0083	2.053e-05	56.0	2BIBC@1|root,32CH4@2|Bacteria,1PDD7@1224|Proteobacteria,435G3@68525|delta/epsilon subdivisions,2WZTJ@28221|Deltaproteobacteria,2Z2QE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_525800_4	1521187.JPIM01000045_gene1429	2.211e-11	78.0	COG0457@1|root,COG0457@2|Bacteria,2GBDY@200795|Chloroflexi,375DC@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
CMS3_k127_525800_1	502025.Hoch_6486	3.261e-142	467.0	COG2244@1|root,COG2244@2|Bacteria,1QT9H@1224|Proteobacteria,439PF@68525|delta/epsilon subdivisions,2X50Z@28221|Deltaproteobacteria,2YZYN@29|Myxococcales	28221|Deltaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt
CMS3_k127_525800_0	1192034.CAP_7313	4.206e-230	754.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
CMS3_k127_5260916_10	502025.Hoch_3892	5.276e-09	67.0	2EQUD@1|root,33IE5@2|Bacteria,1N9A0@1224|Proteobacteria,43CZ1@68525|delta/epsilon subdivisions,2X878@28221|Deltaproteobacteria,2Z3MG@29|Myxococcales	1224|Proteobacteria	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS3_k127_5260916_6	247490.KSU1_C0452	2.171e-25	124.0	COG1629@1|root,COG4771@2|Bacteria,2J2B7@203682|Planctomycetes	203682|Planctomycetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS3_k127_5260916_8	391625.PPSIR1_18477	3.044e-11	72.0	COG3921@1|root,COG3921@2|Bacteria	2|Bacteria	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
CMS3_k127_5260916_2	1210884.HG799466_gene12339	3.662e-99	347.0	COG2204@1|root,COG2204@2|Bacteria,2IY6A@203682|Planctomycetes	203682|Planctomycetes	T	Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat
CMS3_k127_5260916_0	502025.Hoch_4591	1.773e-112	368.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,2YTSA@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_5260916_1	502025.Hoch_4590	3.014e-101	337.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2YV3C@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_5260916_5	502025.Hoch_4589	1.068e-46	178.0	COG0745@1|root,COG3215@1|root,COG0745@2|Bacteria,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_5260916_13	269799.Gmet_3418	0.0001408	50.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
CMS3_k127_5260916_3	398767.Glov_0508	5.182e-98	332.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43UKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
CMS3_k127_5260916_7	502025.Hoch_4588	4.869e-24	109.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2YW0Y@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_5260916_4	290397.Adeh_0135	5.688e-55	209.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS3_k127_5260916_12	1437824.BN940_04156	9.213e-08	59.0	COG1886@1|root,COG1886@2|Bacteria,1N8MX@1224|Proteobacteria,2WFSY@28216|Betaproteobacteria,3T3K8@506|Alcaligenaceae	28216|Betaproteobacteria	NU	COG1886 Flagellar motor switch type III secretory pathway protein	-	-	-	ko:K03225	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1	-	-	FliMN_C
CMS3_k127_5278565_1	1192034.CAP_7183	2.292e-91	318.0	COG2303@1|root,COG2303@2|Bacteria,1PEB3@1224|Proteobacteria,42WR0@68525|delta/epsilon subdivisions,2WS23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_5278565_0	502025.Hoch_0686	1.738e-143	471.0	COG3203@1|root,COG3203@2|Bacteria,1QVA0@1224|Proteobacteria,42P8X@68525|delta/epsilon subdivisions,2WM47@28221|Deltaproteobacteria,2YXTN@29|Myxococcales	28221|Deltaproteobacteria	M	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,FG-GAP_2
CMS3_k127_5284112_1	502025.Hoch_0049	2.276e-27	112.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,42SG1@68525|delta/epsilon subdivisions,2WP1E@28221|Deltaproteobacteria,2YUU8@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CMS3_k127_5284112_0	502025.Hoch_0048	6.977e-100	332.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
CMS3_k127_528729_10	443143.GM18_3946	3.091e-44	183.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,43W1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_528729_15	1121920.AUAU01000026_gene1445	3.683e-22	104.0	COG3303@1|root,COG3303@2|Bacteria,3Y9EA@57723|Acidobacteria	57723|Acidobacteria	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_528729_14	448385.sce4507	1.207e-22	108.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
CMS3_k127_528729_20	391625.PPSIR1_00085	8.988e-06	59.0	COG3712@1|root,COG3712@2|Bacteria,1PBZ9@1224|Proteobacteria,433U5@68525|delta/epsilon subdivisions,2X3GP@28221|Deltaproteobacteria,2YW0J@29|Myxococcales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,zf-HC2
CMS3_k127_528729_12	1121456.ATVA01000015_gene2497	3.718e-23	104.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2X2AA@28221|Deltaproteobacteria,2MF3K@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FixO
CMS3_k127_528729_16	1028801.RG1141_PA14930	7.61e-13	73.0	COG0784@1|root,COG2199@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4B88G@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
CMS3_k127_528729_19	1219031.BBJR01000052_gene1527	4.437e-08	63.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,4AC4K@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator	vsrC	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_528729_13	1121904.ARBP01000009_gene4385	4.731e-23	111.0	2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes,47SQF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_528729_9	502025.Hoch_6702	2.567e-45	176.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WN6T@28221|Deltaproteobacteria,2Z0I0@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS3_k127_528729_21	1122963.AUHB01000007_gene3674	2.654e-05	55.0	COG2345@1|root,COG2345@2|Bacteria,1RIDX@1224|Proteobacteria,2U9M4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
CMS3_k127_528729_11	502025.Hoch_3437	1.913e-28	127.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS3_k127_528729_17	326297.Sama_0439	1.16e-10	75.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,2QEJS@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,PKD,P_proprotein,Peptidase_S8
CMS3_k127_528729_1	502025.Hoch_2147	3.977e-157	517.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2YVAG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_528729_6	502025.Hoch_2148	1.469e-98	331.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_528729_2	502025.Hoch_2149	8.839e-155	504.0	COG0827@1|root,COG0827@2|Bacteria,1MVG5@1224|Proteobacteria,42PJ2@68525|delta/epsilon subdivisions,2WPNM@28221|Deltaproteobacteria,2YVTI@29|Myxococcales	28221|Deltaproteobacteria	L	DNA modification methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
CMS3_k127_528729_3	502025.Hoch_5100	5.086e-149	484.0	COG0247@1|root,COG0247@2|Bacteria,1QA7J@1224|Proteobacteria,434VW@68525|delta/epsilon subdivisions,2X91N@28221|Deltaproteobacteria,2Z1GG@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS3_k127_528729_7	88036.EFJ08678	8.703e-76	291.0	COG0626@1|root,KOG0053@2759|Eukaryota,37K09@33090|Viridiplantae,3G79I@35493|Streptophyta	35493|Streptophyta	E	Cystathionine gamma-synthase	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
CMS3_k127_528729_4	502025.Hoch_3322	6.816e-136	480.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria,2YXRA@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_528729_0	502025.Hoch_3321	2.853e-223	709.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria,2YXRA@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_528729_5	391625.PPSIR1_30230	1.468e-121	405.0	COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,42R72@68525|delta/epsilon subdivisions,2WMSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_528729_8	797209.ZOD2009_04167	1.019e-45	185.0	COG1250@1|root,arCOG00250@2157|Archaea,2XT9S@28890|Euryarchaeota,23TDY@183963|Halobacteria	183963|Halobacteria	I	3-hydroxyacyl-CoA dehydrogenase	hbd3	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_5319944_8	501479.ACNW01000106_gene4802	5.925e-05	55.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4214,GDPD,He_PIG,HemolysinCabind,PPC,Peptidase_M10_C
CMS3_k127_5319944_6	483219.LILAB_21390	4.816e-88	330.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,43AJ6@68525|delta/epsilon subdivisions,2X5ZG@28221|Deltaproteobacteria,2Z37W@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7,zf-HC2
CMS3_k127_5319944_3	1254432.SCE1572_51245	2.315e-120	430.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat
CMS3_k127_5319944_7	1323663.AROI01000051_gene3986	8.419e-11	73.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,1RN3V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	gppA	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643	HD,Ppx-GppA
CMS3_k127_5319944_4	391625.PPSIR1_33259	4.87e-119	393.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2YXG3@29|Myxococcales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_5319944_0	502025.Hoch_5707	4.842e-317	997.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,2YU71@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS3_k127_5319944_5	909663.KI867150_gene836	4.722e-107	355.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2MQZ1@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_5319944_2	1379270.AUXF01000001_gene2083	5.941e-135	436.0	COG0451@1|root,COG0451@2|Bacteria,1ZUJJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_5319944_1	1192034.CAP_8536	2.209e-260	817.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales	2|Bacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Big_3_2,Big_3_3,CARDB,DUF1573,DUF4347,F5_F8_type_C,FlgD_ig,Kelch_4,Laminin_G_3,Lectin_C,PAP2,Prenyltrans,VCBS
CMS3_k127_5378346_11	1254432.SCE1572_06465	1.881e-08	57.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5378346_12	1463861.JNXE01000035_gene2572	1.866e-06	62.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,2GMBZ@201174|Actinobacteria	201174|Actinobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NB-ARC,TPR_10,TPR_12,TPR_6
CMS3_k127_5378346_6	378806.STAUR_5358	2.601e-41	175.0	COG1729@1|root,COG1729@2|Bacteria,1N780@1224|Proteobacteria,42V4V@68525|delta/epsilon subdivisions,2WR6U@28221|Deltaproteobacteria,2YW0N@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5378346_10	1144275.COCOR_05146	3.227e-09	66.0	2AIZJ@1|root,319HM@2|Bacteria,1Q2SU@1224|Proteobacteria,438EK@68525|delta/epsilon subdivisions,2X3PJ@28221|Deltaproteobacteria,2YWS6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
CMS3_k127_5378346_8	1144275.COCOR_05233	9.838e-15	84.0	COG2849@1|root,COG2849@2|Bacteria,1NMUU@1224|Proteobacteria,432BU@68525|delta/epsilon subdivisions,2WT7D@28221|Deltaproteobacteria,2Z2M9@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS3_k127_5378346_1	502025.Hoch_5946	7.959e-115	390.0	2E7E8@1|root,331X9@2|Bacteria,1NB1R@1224|Proteobacteria,42WG3@68525|delta/epsilon subdivisions,2WS1D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
CMS3_k127_5378346_2	502025.Hoch_5947	1.9e-112	376.0	COG3562@1|root,COG3562@2|Bacteria,1MUZT@1224|Proteobacteria,42P5Z@68525|delta/epsilon subdivisions,2WNDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Capsule polysaccharide biosynthesis protein	-	-	-	ko:K07265	-	-	-	-	ko00000	-	-	-	Capsule_synth
CMS3_k127_5378346_3	502025.Hoch_5949	5.49e-86	311.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2YYFF@29|Myxococcales	28221|Deltaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS3_k127_5378346_5	748658.KB907316_gene472	1.412e-41	175.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1WY5Q@135613|Chromatiales	135613|Chromatiales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
CMS3_k127_5378346_0	502025.Hoch_5951	2.535e-129	417.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2YUE2@29|Myxococcales	28221|Deltaproteobacteria	H	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS3_k127_5378346_9	460265.Mnod_2049	9.335e-11	72.0	COG3524@1|root,COG3524@2|Bacteria,1R3ZY@1224|Proteobacteria,2U0I2@28211|Alphaproteobacteria,1JSVH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	COG3524 Capsule polysaccharide export protein	-	-	-	ko:K10107	ko02010,map02010	M00249	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101	-	-	-
CMS3_k127_5378346_7	502025.Hoch_5954	4.602e-25	106.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2YVKG@29|Myxococcales	28221|Deltaproteobacteria	GM	ABC transporter	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_537990_1	502025.Hoch_3747	3.445e-104	343.0	COG0515@1|root,COG3170@1|root,COG0515@2|Bacteria,COG3170@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUMV@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_537990_6	391625.PPSIR1_00907	7.754e-20	102.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_537990_2	485913.Krac_9897	1.11e-81	287.0	COG0661@1|root,COG0661@2|Bacteria,2G6DN@200795|Chloroflexi	2|Bacteria	S	PFAM ABC-1 domain protein	aarF	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CMS3_k127_537990_0	665571.STHERM_c16030	5.846e-226	715.0	COG0441@1|root,COG0441@2|Bacteria,2J5ID@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
CMS3_k127_537990_3	667014.Thein_1593	2.287e-56	203.0	COG0290@1|root,COG0290@2|Bacteria,2GH65@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS3_k127_537990_7	502025.Hoch_3746	4.262e-18	85.0	COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WREY@28221|Deltaproteobacteria,2Z2C4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS3_k127_537990_4	502025.Hoch_3745	1.638e-41	155.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,2Z23K@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS3_k127_5380537_15	378806.STAUR_3552	1.719e-18	98.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,42P3W@68525|delta/epsilon subdivisions,2WNCT@28221|Deltaproteobacteria,2YYDE@29|Myxococcales	28221|Deltaproteobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS3_k127_5380537_2	1163408.UU9_03113	4.293e-133	429.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,1X399@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_5380537_1	661478.OP10G_2698	3.793e-134	436.0	COG1088@1|root,COG1088@2|Bacteria	2|Bacteria	M	dTDP-glucose 4,6-dehydratase activity	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_5380537_11	1538295.JY96_18535	7.116e-49	186.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,2VIY0@28216|Betaproteobacteria,1KNNU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_5380537_18	1040982.AXAL01000011_gene1174	3.061e-11	69.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_17	1288494.EBAPG3_25650	1.088e-13	74.0	COG1553@1|root,COG1553@2|Bacteria,1N3C3@1224|Proteobacteria,2WCPP@28216|Betaproteobacteria,373SV@32003|Nitrosomonadales	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_5380537_4	264732.Moth_0199	1.769e-78	276.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42EN3@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase class V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_5380537_6	383372.Rcas_0264	4.236e-67	256.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_20	448385.sce1247	2.204e-08	68.0	COG1621@1|root,COG1621@2|Bacteria,1PG02@1224|Proteobacteria,434QU@68525|delta/epsilon subdivisions,2X8ZG@28221|Deltaproteobacteria,2Z15S@29|Myxococcales	28221|Deltaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_5	1254432.SCE1572_05300	2.096e-72	276.0	COG5184@1|root,COG5184@2|Bacteria,1PEJQ@1224|Proteobacteria,439SY@68525|delta/epsilon subdivisions,2X560@28221|Deltaproteobacteria,2Z05W@29|Myxococcales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_5380537_16	448385.sce1247	1.398e-14	89.0	COG1621@1|root,COG1621@2|Bacteria,1PG02@1224|Proteobacteria,434QU@68525|delta/epsilon subdivisions,2X8ZG@28221|Deltaproteobacteria,2Z15S@29|Myxococcales	28221|Deltaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_21	448385.sce6598	2.683e-08	67.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2Z0FT@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD,fn3
CMS3_k127_5380537_9	326427.Cagg_0670	1.415e-52	210.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
CMS3_k127_5380537_12	867845.KI911784_gene654	1.11e-39	169.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_5380537_13	502025.Hoch_6135	6.324e-38	158.0	2C9M1@1|root,2ZSUM@2|Bacteria,1R0NN@1224|Proteobacteria,43CZC@68525|delta/epsilon subdivisions,2X87J@28221|Deltaproteobacteria,2Z3MM@29|Myxococcales	502025.Hoch_6135|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_3	502025.Hoch_0107	2.179e-100	336.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,2YZZD@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
CMS3_k127_5380537_19	1297742.A176_07060	2.022e-09	70.0	COG4935@1|root,COG4935@2|Bacteria,1Q3W5@1224|Proteobacteria,4343N@68525|delta/epsilon subdivisions,2X525@28221|Deltaproteobacteria,2Z009@29|Myxococcales	28221|Deltaproteobacteria	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein
CMS3_k127_5380537_8	502025.Hoch_5220	1.249e-55	203.0	COG3386@1|root,COG3386@2|Bacteria,1NFEJ@1224|Proteobacteria,43BX0@68525|delta/epsilon subdivisions,2X77S@28221|Deltaproteobacteria,2YVY8@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_0	502025.Hoch_5821	4.544e-167	529.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria	1224|Proteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5380537_14	1240349.ANGC01000083_gene101	2.429e-19	96.0	COG1309@1|root,COG1309@2|Bacteria,2IBGU@201174|Actinobacteria,4G6A7@85025|Nocardiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_10	215803.DB30_3347	1.361e-50	202.0	COG3005@1|root,COG3005@2|Bacteria,1Q3RM@1224|Proteobacteria,439JH@68525|delta/epsilon subdivisions,2X4W4@28221|Deltaproteobacteria,2YZQG@29|Myxococcales	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5380537_7	1278073.MYSTI_05014	2.051e-60	239.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,42NYN@68525|delta/epsilon subdivisions,2WJFE@28221|Deltaproteobacteria,2YYKS@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
CMS3_k127_5380537_22	319003.Bra1253DRAFT_01363	5.613e-08	62.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2U1EH@28211|Alphaproteobacteria,3K65K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS3_k127_5409787_3	1123368.AUIS01000019_gene1214	2.58e-154	506.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_5409787_10	1123368.AUIS01000019_gene1213	7.826e-61	213.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales	225057|Acidithiobacillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_5409787_2	448385.sce8916	2.741e-194	660.0	COG0515@1|root,COG2909@1|root,COG0515@2|Bacteria,COG2909@2|Bacteria,1QA6R@1224|Proteobacteria,4393M@68525|delta/epsilon subdivisions,2X49J@28221|Deltaproteobacteria,2YYJG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5409787_11	502025.Hoch_5840	3.554e-37	153.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42STT@68525|delta/epsilon subdivisions,2WPJI@28221|Deltaproteobacteria,2YVDD@29|Myxococcales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_5409787_1	502025.Hoch_5839	1.553e-270	880.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJEY@28221|Deltaproteobacteria,2YUDX@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CMS3_k127_5409787_5	502025.Hoch_5838	1.705e-117	403.0	COG0845@1|root,COG0845@2|Bacteria,1Q2C6@1224|Proteobacteria,437YK@68525|delta/epsilon subdivisions,2X38G@28221|Deltaproteobacteria,2YUTX@29|Myxococcales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3
CMS3_k127_5409787_6	215803.DB30_6882	4.026e-116	393.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5409787_0	502025.Hoch_6348	0.0	1079.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_5409787_9	502025.Hoch_6347	9.169e-76	282.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_5409787_7	502025.Hoch_6346	6.671e-115	387.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MU2@68525|delta/epsilon subdivisions,2WMYH@28221|Deltaproteobacteria,2Z0RU@29|Myxococcales	28221|Deltaproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_5409787_4	1192034.CAP_5604	7.123e-122	421.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
CMS3_k127_5409787_8	1192034.CAP_7388	6.206e-80	273.0	COG0366@1|root,COG0535@1|root,COG0366@2|Bacteria,COG0535@2|Bacteria,1NJ3W@1224|Proteobacteria,42PQJ@68525|delta/epsilon subdivisions,2WKAV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
CMS3_k127_544989_9	7739.XP_002606139.1	2.417e-17	88.0	KOG1216@1|root,KOG1217@1|root,KOG1216@2759|Eukaryota,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,48CY1@7711|Chordata	33208|Metazoa	T	EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_3,EGF_CA,Lectin_C,TIL
CMS3_k127_544989_3	243231.GSU3259	1.196e-120	406.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria,43U0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
CMS3_k127_544989_7	502025.Hoch_6281	2.887e-52	202.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
CMS3_k127_544989_2	163908.KB235896_gene663	1.91e-180	587.0	COG4097@1|root,COG5126@1|root,COG4097@2|Bacteria,COG5126@2|Bacteria,1G2G1@1117|Cyanobacteria,1HKUB@1161|Nostocales	1117|Cyanobacteria	P	FAD-binding domain	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	EF-hand_7,EF-hand_8,FAD_binding_8,Ferric_reduct,NAD_binding_1,NAD_binding_6
CMS3_k127_544989_0	391625.PPSIR1_28921	0.0	1049.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_544989_8	391625.PPSIR1_28916	8.545e-44	176.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42RCZ@68525|delta/epsilon subdivisions,2WN2W@28221|Deltaproteobacteria,2YWQC@29|Myxococcales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS3_k127_544989_12	944564.HMPREF9200_1656	2.625e-13	83.0	COG1538@1|root,COG1538@2|Bacteria,1TRDS@1239|Firmicutes,4H2S7@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	tolC	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_544989_10	391625.PPSIR1_28911	1.367e-16	87.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_544989_11	448385.sce7595	5.081e-15	79.0	2DR0H@1|root,339NS@2|Bacteria,1R3N7@1224|Proteobacteria,42X1P@68525|delta/epsilon subdivisions,2X8S7@28221|Deltaproteobacteria,2Z3NK@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
CMS3_k127_544989_5	290397.Adeh_2273	1.009e-86	299.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,42RCU@68525|delta/epsilon subdivisions,2X2M1@28221|Deltaproteobacteria,2Z04Y@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS3_k127_544989_1	290397.Adeh_2274	3.99e-262	816.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions,2WJUK@28221|Deltaproteobacteria,2YWYV@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
CMS3_k127_544989_4	290397.Adeh_2275	1.402e-102	348.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,43AKU@68525|delta/epsilon subdivisions,2X60W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome C oxidase subunit II, transmembrane domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CMS3_k127_544989_6	290397.Adeh_2276	9.599e-57	209.0	COG1999@1|root,COG1999@2|Bacteria,1R9EM@1224|Proteobacteria,42N5F@68525|delta/epsilon subdivisions,2WKG7@28221|Deltaproteobacteria,2YV22@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
CMS3_k127_5482807_0	215803.DB30_5799	6.49e-122	400.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,437GZ@68525|delta/epsilon subdivisions,2X2QB@28221|Deltaproteobacteria,2YUHU@29|Myxococcales	28221|Deltaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_5482807_1	2002.JOEQ01000004_gene3067	1.575e-07	63.0	COG0558@1|root,COG0558@2|Bacteria,2IETF@201174|Actinobacteria,4EFR0@85012|Streptosporangiales	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_5484567_2	404589.Anae109_0189	3.515e-48	184.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
CMS3_k127_5484567_1	2002.JOEQ01000021_gene6740	5.895e-74	269.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EJI6@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_5484567_0	2002.JOEQ01000021_gene6740	1.177e-97	356.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4EJI6@85012|Streptosporangiales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_5490700_3	1379698.RBG1_1C00001G0115	7.934e-39	162.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5490700_1	459349.CLOAM0589	3.41e-112	373.0	28II6@1|root,2Z8JB@2|Bacteria,2NNT1@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5490700_0	502025.Hoch_1919	0.0	1042.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,2YUGV@29|Myxococcales	28221|Deltaproteobacteria	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS3_k127_5490700_2	1121935.AQXX01000127_gene1191	5.85e-66	258.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,1S91X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_5500974_5	1144275.COCOR_06625	4.579e-10	68.0	COG3637@1|root,COG3637@2|Bacteria,1Q9QE@1224|Proteobacteria,434IR@68525|delta/epsilon subdivisions,2X8WU@28221|Deltaproteobacteria,2Z0RY@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS3_k127_5500974_1	1123024.AUII01000015_gene3750	8.024e-87	306.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DXC9@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
CMS3_k127_5500974_3	208444.JNYY01000005_gene6334	6.233e-32	133.0	COG1309@1|root,COG1653@1|root,COG1309@2|Bacteria,COG1653@2|Bacteria,2IIK3@201174|Actinobacteria,4E2YS@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_5500974_4	742817.HMPREF9449_01618	1.364e-22	102.0	2ARAZ@1|root,31GKZ@2|Bacteria,4NKJD@976|Bacteroidetes,2FPQT@200643|Bacteroidia,22Y6A@171551|Porphyromonadaceae	976|Bacteroidetes	S	Domain of unknown function (DUF3332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3332
CMS3_k127_5500974_0	1192034.CAP_6957	7.992e-117	382.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,43B0F@68525|delta/epsilon subdivisions,2X6EI@28221|Deltaproteobacteria,2Z3AT@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2,S4
CMS3_k127_5500974_2	404589.Anae109_3775	9.71e-51	200.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_5512503_0	502025.Hoch_0252	2.765e-246	809.0	COG1196@1|root,COG4796@1|root,COG1196@2|Bacteria,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS3_k127_5512503_5	502025.Hoch_0250	1.321e-18	100.0	COG3167@1|root,COG3167@2|Bacteria	2|Bacteria	NU	carbon utilization	mshJ	-	-	ko:K02664,ko:K02665,ko:K12280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO,T2SSM,T2SSM_b
CMS3_k127_5512503_3	502025.Hoch_0249	1.965e-37	160.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
CMS3_k127_5512503_1	502025.Hoch_0248	2.741e-156	499.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_5512503_2	290397.Adeh_0639	2.127e-128	427.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5535313_1	1192034.CAP_5278	3.226e-57	211.0	COG1357@1|root,COG1357@2|Bacteria,1RJ94@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5535313_0	298653.Franean1_6417	1.828e-67	244.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4EWFM@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_5535313_2	1449350.OCH239_03795	5.28e-13	83.0	2BHIR@1|root,33SZU@2|Bacteria,1NR6P@1224|Proteobacteria,2UQC7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_55627_0	502025.Hoch_0502	1.617e-177	578.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_0502|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_55627_1	1192034.CAP_3945	7.308e-121	402.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,438QR@68525|delta/epsilon subdivisions,2X3Y0@28221|Deltaproteobacteria,2YXIR@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_55627_4	38727.Pavir.Aa02930.1.p	2.101e-39	157.0	COG1234@1|root,2QVD0@2759|Eukaryota,37J4D@33090|Viridiplantae,3GGSH@35493|Streptophyta,3KTH7@4447|Liliopsida,3IN1Y@38820|Poales	35493|Streptophyta	S	Beta-lactamase superfamily domain	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS3_k127_55627_2	502025.Hoch_4569	2.865e-95	328.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_55627_3	768706.Desor_4304	5.461e-91	320.0	COG0210@1|root,COG1112@1|root,COG2852@1|root,COG0210@2|Bacteria,COG1112@2|Bacteria,COG2852@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia,263S0@186807|Peptococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559
CMS3_k127_5586175_2	502025.Hoch_5012	4.272e-128	415.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2YTVY@29|Myxococcales	28221|Deltaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS3_k127_5586175_3	502025.Hoch_3949	3.552e-74	268.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2X3AE@28221|Deltaproteobacteria,2YV4E@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS3_k127_5586175_0	502025.Hoch_3948	6.083e-193	610.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2YU2Z@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS3_k127_5586175_1	502025.Hoch_3947	3.296e-145	488.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2YV05@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS3_k127_5586175_4	502025.Hoch_3946	7.615e-46	187.0	2EFBC@1|root,33949@2|Bacteria,1NQ59@1224|Proteobacteria,42XCI@68525|delta/epsilon subdivisions,2WT2R@28221|Deltaproteobacteria,2Z201@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5586175_7	483219.LILAB_29420	1.481e-13	84.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,OmpA,Phenol_MetA_deg,TSP_3
CMS3_k127_5586175_5	502025.Hoch_6837	2.903e-34	133.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS3_k127_561613_12	502025.Hoch_0050	5.057e-05	53.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YYJX@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_561613_0	502025.Hoch_0051	3.191e-137	457.0	COG1807@1|root,COG1807@2|Bacteria,1N8ZV@1224|Proteobacteria,42WB6@68525|delta/epsilon subdivisions,2WRTT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CMS3_k127_561613_8	1122919.KB905588_gene4060	5.111e-21	104.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS3_k127_561613_7	1192034.CAP_3241	4.21e-26	126.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
CMS3_k127_561613_3	502025.Hoch_0054	4.779e-89	303.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1PQD2@1224|Proteobacteria,4323R@68525|delta/epsilon subdivisions,2WXJB@28221|Deltaproteobacteria,2Z10C@29|Myxococcales	28221|Deltaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_1,TPR_17,TPR_8
CMS3_k127_561613_5	502025.Hoch_0489	1.404e-73	253.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
CMS3_k127_561613_11	502025.Hoch_0488	1.302e-15	87.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	-
CMS3_k127_561613_1	502025.Hoch_0487	4.871e-116	379.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,42VIT@68525|delta/epsilon subdivisions,2WS62@28221|Deltaproteobacteria,2YZJ3@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS3_k127_561613_2	502025.Hoch_0486	4.276e-91	305.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,2YUTJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS3_k127_561613_4	502025.Hoch_0485	1.626e-81	279.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2WQ6V@28221|Deltaproteobacteria,2YVMH@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS3_k127_561613_10	62928.azo2142	2.057e-17	95.0	COG2905@1|root,COG2905@2|Bacteria,1N7MU@1224|Proteobacteria,2VVGU@28216|Betaproteobacteria,2KZVZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_561613_9	886293.Sinac_1156	1.571e-18	95.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_565182_10	575540.Isop_1997	9.013e-20	91.0	COG1595@1|root,COG1595@2|Bacteria,2J0KR@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_565182_8	765912.Thimo_0827	1.535e-25	121.0	COG0641@1|root,COG0641@2|Bacteria,1QEJV@1224|Proteobacteria,1SIWC@1236|Gammaproteobacteria,1WZPC@135613|Chromatiales	135613|Chromatiales	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_565182_11	755731.Clo1100_3357	4.525e-19	98.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,36IC8@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_565182_9	204669.Acid345_3980	8.139e-21	109.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_8
CMS3_k127_565182_1	404589.Anae109_3191	3.344e-145	483.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
CMS3_k127_565182_6	1192034.CAP_5108	1.08e-43	168.0	COG1595@1|root,COG1595@2|Bacteria,1NBAJ@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_565182_7	644801.Psest_3192	1.308e-33	144.0	COG2199@1|root,COG3706@2|Bacteria,1RD8D@1224|Proteobacteria,1SYKF@1236|Gammaproteobacteria,1Z108@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	2.7.7.65	ko:K21019	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	CIA30,GGDEF
CMS3_k127_565182_5	1120973.AQXL01000121_gene61	3.346e-44	183.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279ZW@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_565182_2	28042.GU90_13770	4.001e-139	455.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DZBV@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	fadD36	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087	-	ko:K12429,ko:K18662	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_565182_12	479435.Kfla_0902	5.958e-11	73.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4DS6I@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_565182_0	502025.Hoch_3357	6.569e-169	549.0	COG4402@1|root,COG4402@2|Bacteria,1QA5C@1224|Proteobacteria,434UU@68525|delta/epsilon subdivisions,2WZ5W@28221|Deltaproteobacteria,2Z1E4@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_565182_3	1254432.SCE1572_51745	3.934e-122	410.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_565182_13	1380356.JNIK01000013_gene4284	4.607e-06	55.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4ETXS@85013|Frankiales	201174|Actinobacteria	EP	Oligopeptide/dipeptide transporter, C-terminal region	dppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_5686662_5	112098.XP_008615955.1	6.289e-50	207.0	2EN7E@1|root,2SRQ7@2759|Eukaryota	2759|Eukaryota	O	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5686662_6	1313172.YM304_13720	3.893e-48	201.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM26,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
CMS3_k127_5686662_11	324057.Pjdr2_0674	1.996e-10	76.0	COG3934@1|root,COG4124@1|root,COG3934@2|Bacteria,COG4124@2|Bacteria,1V19K@1239|Firmicutes,4IQ1F@91061|Bacilli,2765Y@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5686662_10	1283299.AUKG01000001_gene1561	6.947e-14	87.0	COG2706@1|root,COG2723@1|root,COG3209@1|root,COG2706@2|Bacteria,COG2723@2|Bacteria,COG3209@2|Bacteria,2I7W7@201174|Actinobacteria,4CU6U@84995|Rubrobacteria	2|Bacteria	GM	COG3209 Rhs family protein	-	-	-	ko:K21000	ko02025,map02025	-	-	-	ko00000,ko00001	-	GH39	-	He_PIG,Lactonase,RHS_repeat
CMS3_k127_5686662_4	502025.Hoch_4207	1.34e-63	223.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2YV5G@29|Myxococcales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_5686662_0	502025.Hoch_4206	0.0	1509.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2YUKG@29|Myxococcales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS3_k127_5686662_3	502025.Hoch_4205	9.33e-70	244.0	COG1413@1|root,COG1413@2|Bacteria,1PC2V@1224|Proteobacteria,4387S@68525|delta/epsilon subdivisions,2X3HJ@28221|Deltaproteobacteria,2YW4Z@29|Myxococcales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_5686662_12	404589.Anae109_3722	2.752e-07	63.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,LRR_5,Peptidase_C1,TIG
CMS3_k127_5686662_2	391625.PPSIR1_00610	9.682e-134	445.0	COG0402@1|root,COG5184@1|root,COG0402@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,RCC1_2
CMS3_k127_5686662_8	378806.STAUR_7433	1.071e-29	130.0	COG1361@1|root,COG3055@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5686662_14	1242864.D187_000504	4.808e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,1PXHP@1224|Proteobacteria,434K6@68525|delta/epsilon subdivisions,2WYXE@28221|Deltaproteobacteria,2Z0V1@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16
CMS3_k127_5686662_1	502025.Hoch_4202	2.111e-275	861.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2YXGK@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_5695153_1	502025.Hoch_6531	1.071e-159	511.0	COG0531@1|root,COG0531@2|Bacteria,1R4IZ@1224|Proteobacteria,42MTQ@68525|delta/epsilon subdivisions,2WK39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
CMS3_k127_5695153_6	502025.Hoch_1918	1.143e-85	299.0	COG2304@1|root,COG2304@2|Bacteria,1Q8X2@1224|Proteobacteria,439TN@68525|delta/epsilon subdivisions,2X571@28221|Deltaproteobacteria,2Z07B@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_5695153_0	502025.Hoch_6348	0.0	1090.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_5695153_5	502025.Hoch_6347	2.146e-104	353.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_5695153_4	502025.Hoch_6346	4.108e-138	469.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MU2@68525|delta/epsilon subdivisions,2WMYH@28221|Deltaproteobacteria,2Z0RU@29|Myxococcales	28221|Deltaproteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_5695153_11	502025.Hoch_6345	7.626e-36	144.0	COG1309@1|root,COG1309@2|Bacteria,1NDYG@1224|Proteobacteria,42WJ9@68525|delta/epsilon subdivisions,2X293@28221|Deltaproteobacteria,2YZAR@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5695153_15	644283.Micau_4758	1.953e-05	56.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4DEEW@85008|Micromonosporales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_5695153_8	350054.Mflv_4603	1.563e-64	230.0	COG0300@1|root,COG0300@2|Bacteria,2I2VP@201174|Actinobacteria,237EA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5695153_14	1390370.O203_09930	2.789e-12	80.0	COG2717@1|root,COG2717@2|Bacteria,1R4CY@1224|Proteobacteria,1SJ59@1236|Gammaproteobacteria,1YJ9W@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
CMS3_k127_5695153_7	1278073.MYSTI_00197	8.024e-80	278.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2Z2WE@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
CMS3_k127_5695153_3	1340493.JNIF01000004_gene1069	7.222e-156	499.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS3_k127_5695153_12	502025.Hoch_4464	1.085e-32	129.0	COG1977@1|root,COG1977@2|Bacteria,1N4M4@1224|Proteobacteria,43BB7@68525|delta/epsilon subdivisions,2X6QD@28221|Deltaproteobacteria,2Z3C9@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
CMS3_k127_5695153_13	306281.AJLK01000102_gene3405	1.021e-28	122.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5695153_9	710687.KI912270_gene5103	7.07e-53	207.0	COG0500@1|root,COG2226@2|Bacteria,2GJUF@201174|Actinobacteria,236M1@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_5695153_2	448385.sce1307	1.38e-159	508.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2Z30G@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS3_k127_5702382_4	886293.Sinac_1156	7.778e-07	53.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5702382_2	457429.ABJI02000832_gene2528	5.966e-21	101.0	2ATW3@1|root,31JFB@2|Bacteria,2IJBG@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_5702382_1	1449346.JQMO01000003_gene6900	3.619e-123	417.0	COG1960@1|root,COG1960@2|Bacteria,2GKRK@201174|Actinobacteria,2M0C6@2063|Kitasatospora	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5702382_0	1174528.JH992893_gene5692	2.263e-310	1009.0	COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1JKIU@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Abhydrolase_1,Acyl_transf_1,Hydrolase_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Sulfotransfer_3,ketoacyl-synt
CMS3_k127_5702382_3	380358.XALC_0934	1.493e-07	54.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RWVV@1236|Gammaproteobacteria,1XAIA@135614|Xanthomonadales	135614|Xanthomonadales	H	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_5702420_1	502025.Hoch_4987	3.805e-78	265.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_5702420_11	202952.BBLI01000004_gene491	2.502e-06	54.0	2DR59@1|root,33A7S@2|Bacteria,1NMH2@1224|Proteobacteria,1SIVW@1236|Gammaproteobacteria,3NS87@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5702420_7	502025.Hoch_2476	3.763e-15	82.0	COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria,42T5V@68525|delta/epsilon subdivisions,2WS5U@28221|Deltaproteobacteria,2YVW0@29|Myxococcales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
CMS3_k127_5702420_5	1144275.COCOR_07432	3.304e-38	156.0	COG0784@1|root,COG3447@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3447@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_5702420_10	679926.Mpet_0602	7.114e-08	62.0	COG0642@1|root,arCOG02352@1|root,arCOG02385@1|root,arCOG06712@1|root,arCOG02352@2157|Archaea,arCOG02385@2157|Archaea,arCOG06192@2157|Archaea,arCOG06193@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_5702420_8	1235794.C811_01231	4.77e-12	75.0	COG2197@1|root,COG2197@2|Bacteria,2IJB1@201174|Actinobacteria,4CV45@84998|Coriobacteriia	84998|Coriobacteriia	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS3_k127_5702420_2	675635.Psed_2779	1.592e-50	191.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DXBC@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_5702420_6	502025.Hoch_5181	1.705e-20	105.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,42W1X@68525|delta/epsilon subdivisions,2WRUK@28221|Deltaproteobacteria,2YV9X@29|Myxococcales	28221|Deltaproteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CMS3_k127_5702420_3	502025.Hoch_4123	1.774e-46	180.0	2CDCQ@1|root,307SM@2|Bacteria,1QST3@1224|Proteobacteria,4355I@68525|delta/epsilon subdivisions,2WZGF@28221|Deltaproteobacteria,2Z23I@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5702420_4	869210.Marky_0211	6.195e-46	169.0	COG1832@1|root,COG1832@2|Bacteria,1WJSJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS3_k127_5702420_0	502025.Hoch_0315	2.347e-98	327.0	COG1597@1|root,COG1597@2|Bacteria,1PV0P@1224|Proteobacteria,42XZR@68525|delta/epsilon subdivisions,2WTF1@28221|Deltaproteobacteria,2YVY3@29|Myxococcales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_5703282_1	502025.Hoch_2686	1.396e-178	575.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_5703282_6	483219.LILAB_20570	1.007e-83	294.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,42T1K@68525|delta/epsilon subdivisions,2WP7Y@28221|Deltaproteobacteria,2YXPS@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
CMS3_k127_5703282_0	502025.Hoch_2255	1.459e-206	649.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YX7D@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_5703282_13	391625.PPSIR1_03883	7.356e-24	118.0	COG0625@1|root,COG0625@2|Bacteria,1RM4P@1224|Proteobacteria	1224|Proteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_N_3
CMS3_k127_5703282_8	502025.Hoch_2436	6.577e-80	291.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5703282_5	502025.Hoch_2437	2.606e-100	337.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2YV5E@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS3_k127_5703282_4	502025.Hoch_2438	1.652e-113	388.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2YUVE@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS3_k127_5703282_9	944481.JAFP01000001_gene1328	1.935e-64	247.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2M703@213113|Desulfurellales	28221|Deltaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS3_k127_5703282_10	502025.Hoch_6573	2.574e-55	213.0	COG0500@1|root,COG2226@2|Bacteria,1QZ7W@1224|Proteobacteria,43CZE@68525|delta/epsilon subdivisions,2WYCC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_5703282_12	266117.Rxyl_0794	9.63e-25	106.0	COG1254@1|root,COG1254@2|Bacteria,2IT6J@201174|Actinobacteria,4CTJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS3_k127_5703282_2	443143.GM18_4161	2.74e-137	447.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,43T9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS3_k127_5703282_3	502025.Hoch_6575	9.144e-132	425.0	COG0639@1|root,COG0639@2|Bacteria,1Q2D6@1224|Proteobacteria,437ZG@68525|delta/epsilon subdivisions,2X39H@28221|Deltaproteobacteria,2YUYG@29|Myxococcales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_5703282_11	502025.Hoch_6576	3.669e-26	123.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,2YVT9@29|Myxococcales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS3_k127_5703282_7	706587.Desti_4009	8.277e-83	287.0	COG3872@1|root,COG3872@2|Bacteria,1RCB0@1224|Proteobacteria,42R3I@68525|delta/epsilon subdivisions,2WMZR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
CMS3_k127_5703282_14	502025.Hoch_6577	2.539e-20	93.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2YTSK@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_5705241_0	502025.Hoch_4987	1.862e-293	908.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_5705241_3	1121930.AQXG01000002_gene1975	3.97e-08	63.0	28IZY@1|root,2Z8X8@2|Bacteria,4NKJG@976|Bacteroidetes,1IYGD@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5705241_2	1192034.CAP_4463	6.352e-10	70.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	peaA	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Cytochrome_CBB3,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
CMS3_k127_5723524_0	502025.Hoch_5748	2.838e-265	841.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS3_k127_5723524_4	290397.Adeh_1445	1.714e-19	94.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5723524_3	391589.RGAI101_4059	4.969e-29	123.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,2P51I@2433|Roseobacter	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_5723524_2	502025.Hoch_6667	1.024e-134	469.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_6667|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5723524_1	937777.Deipe_1399	1.198e-183	587.0	COG1523@1|root,COG1523@2|Bacteria,1WJJM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS3_k127_5726037_4	502025.Hoch_6432	1.393e-155	539.0	COG0312@1|root,COG0312@2|Bacteria,1Q3C0@1224|Proteobacteria,4393A@68525|delta/epsilon subdivisions,2X495@28221|Deltaproteobacteria,2YYIX@29|Myxococcales	28221|Deltaproteobacteria	S	peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_5726037_1	502025.Hoch_6433	1.377e-224	711.0	COG0312@1|root,COG3009@1|root,COG0312@2|Bacteria,COG3009@2|Bacteria,1Q3C0@1224|Proteobacteria,4393A@68525|delta/epsilon subdivisions,2X495@28221|Deltaproteobacteria,2YYIX@29|Myxococcales	28221|Deltaproteobacteria	S	peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_5726037_6	944480.ATUV01000001_gene1386	3.837e-76	279.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2M6ST@213113|Desulfurellales	28221|Deltaproteobacteria	O	Hsp70 protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_5726037_10	502025.Hoch_6434	2.274e-39	157.0	COG0784@1|root,COG4567@1|root,COG0784@2|Bacteria,COG4567@2|Bacteria	2|Bacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg,SBP_bac_3
CMS3_k127_5726037_11	344747.PM8797T_14354	1.123e-37	161.0	COG0793@1|root,COG2234@1|root,COG0793@2|Bacteria,COG2234@2|Bacteria,2IXR2@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M28
CMS3_k127_5726037_3	502025.Hoch_3164	3.209e-199	661.0	COG2304@1|root,COG4676@1|root,COG4783@1|root,COG2304@2|Bacteria,COG4676@2|Bacteria,COG4783@2|Bacteria,1PCRX@1224|Proteobacteria,433WB@68525|delta/epsilon subdivisions,2X9AU@28221|Deltaproteobacteria,2YX4K@29|Myxococcales	28221|Deltaproteobacteria	E	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
CMS3_k127_5726037_0	502025.Hoch_0166	0.0	1044.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_5726037_2	502025.Hoch_0181	4.806e-219	687.0	COG1509@1|root,COG1509@2|Bacteria,1R8HT@1224|Proteobacteria,43DMX@68525|delta/epsilon subdivisions,2X6DS@28221|Deltaproteobacteria,2YUSV@29|Myxococcales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	kamA1	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C
CMS3_k127_5726037_9	502025.Hoch_0180	1.115e-45	168.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_5726037_5	1201288.M900_1005	6.94e-91	322.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,42Y3Q@68525|delta/epsilon subdivisions,2MTU8@213481|Bdellovibrionales,2WT53@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
CMS3_k127_5726037_13	713587.THITH_05010	6.732e-07	62.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
CMS3_k127_5726037_7	502025.Hoch_0362	4.023e-71	263.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,4389R@68525|delta/epsilon subdivisions,2XA3N@28221|Deltaproteobacteria,2YWAI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_5726037_14	313606.M23134_02455	0.0003131	54.0	COG3047@1|root,COG3047@2|Bacteria,4PM1M@976|Bacteroidetes,47XZM@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
CMS3_k127_5726037_8	502025.Hoch_4902	4.144e-65	237.0	COG1073@1|root,COG1073@2|Bacteria,1NKA5@1224|Proteobacteria,438I9@68525|delta/epsilon subdivisions,2X9SF@28221|Deltaproteobacteria,2YX1V@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5738827_5	502025.Hoch_4470	1.278e-34	145.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,43CGP@68525|delta/epsilon subdivisions,2X7RU@28221|Deltaproteobacteria,2YV1F@29|Myxococcales	28221|Deltaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CMS3_k127_5738827_0	1125863.JAFN01000001_gene1833	1.87e-155	507.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_5738827_2	469383.Cwoe_4390	1.668e-57	209.0	COG0327@1|root,COG0327@2|Bacteria,2HQUS@201174|Actinobacteria,4CSMH@84995|Rubrobacteria	84995|Rubrobacteria	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS3_k127_5738827_1	1192034.CAP_5604	3.951e-119	398.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
CMS3_k127_5738827_3	502025.Hoch_3230	7.308e-44	174.0	COG0789@1|root,COG0789@2|Bacteria,1Q71A@1224|Proteobacteria,433UC@68525|delta/epsilon subdivisions,2XA1C@28221|Deltaproteobacteria,2YW54@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_5738827_4	1192034.CAP_7611	1.045e-42	158.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YUC8@29|Myxococcales	28221|Deltaproteobacteria	GM	RmlD substrate binding domain	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_5747826_1	502025.Hoch_5018	4.099e-91	316.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YUC8@29|Myxococcales	28221|Deltaproteobacteria	GM	RmlD substrate binding domain	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_5747826_0	378806.STAUR_2362	6e-115	377.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YU1X@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_5747826_2	1192034.CAP_0612	4.495e-48	198.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_0612|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5747826_3	502025.Hoch_4952	2.415e-06	59.0	COG0745@1|root,COG0745@2|Bacteria,1QVDV@1224|Proteobacteria,43APF@68525|delta/epsilon subdivisions,2X631@28221|Deltaproteobacteria,2Z38J@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
CMS3_k127_5752989_1	502025.Hoch_3629	9.069e-138	439.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43957@68525|delta/epsilon subdivisions,2X4BI@28221|Deltaproteobacteria,2YYP6@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS3_k127_5752989_0	502025.Hoch_3248	0.0	1829.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
CMS3_k127_5752989_2	502025.Hoch_3249	1.368e-122	401.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
CMS3_k127_5752989_9	675635.Psed_2060	1.753e-06	57.0	COG1309@1|root,COG1309@2|Bacteria,2GKE2@201174|Actinobacteria,4E2RY@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5752989_7	1304888.ATWF01000001_gene739	8.714e-22	111.0	COG0457@1|root,COG0457@2|Bacteria,2GG73@200930|Deferribacteres	200930|Deferribacteres	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_5752989_6	1280380.KR100_02380	4.252e-53	204.0	COG2931@1|root,COG3420@1|root,COG2931@2|Bacteria,COG3420@2|Bacteria,1G1I0@1117|Cyanobacteria,1GZV9@1129|Synechococcus	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
CMS3_k127_5752989_4	502025.Hoch_3259	2.039e-95	318.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2YVHT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
CMS3_k127_5752989_5	1254432.SCE1572_01535	2.363e-75	270.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,42Q1N@68525|delta/epsilon subdivisions,2WK3A@28221|Deltaproteobacteria,2Z377@29|Myxococcales	28221|Deltaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
CMS3_k127_5752989_3	1242864.D187_004741	4.757e-118	385.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS3_k127_5757943_2	324057.Pjdr2_0605	7.02e-22	99.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HD58@91061|Bacilli,26UDF@186822|Paenibacillaceae	91061|Bacilli	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS3_k127_5757943_0	6500.XP_005092325.1	5.102e-110	366.0	COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria	33208|Metazoa	ET	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS3_k127_5757943_1	1179773.BN6_04490	8.286e-47	189.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_5758592_0	448385.sce4861	6.621e-13	81.0	COG5337@1|root,COG5337@2|Bacteria,1Q378@1224|Proteobacteria,438XY@68525|delta/epsilon subdivisions,2X9VC@28221|Deltaproteobacteria,2YY5I@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_5773277_3	1192034.CAP_7100	3.461e-09	68.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	peaA	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Cytochrome_CBB3,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
CMS3_k127_5773277_2	1150626.PHAMO_340131	1.309e-11	78.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2TQZ1@28211|Alphaproteobacteria,2JTBK@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
CMS3_k127_5773277_0	1242864.D187_002403	2.879e-80	293.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X7AD@28221|Deltaproteobacteria,2YUMR@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_5780156_0	502025.Hoch_6041	6.954e-267	888.0	COG0470@1|root,COG1413@1|root,COG0470@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,HEAT_2,NB-ARC,TPR_10,TPR_12,Trypsin_2
CMS3_k127_5780156_3	523791.Kkor_1536	4.344e-59	224.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CMS3_k127_5780156_4	1163407.UU7_05349	3.163e-23	117.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1X3Q3@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CMS3_k127_5780156_2	215803.DB30_5174	4.389e-79	291.0	COG3291@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5492@2|Bacteria,1PEIB@1224|Proteobacteria,439WA@68525|delta/epsilon subdivisions,2X5AJ@28221|Deltaproteobacteria,2YWZV@29|Myxococcales	28221|Deltaproteobacteria	N	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
CMS3_k127_5780156_5	1484460.JSWG01000015_gene990	2.697e-15	90.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M
CMS3_k127_5780156_1	502025.Hoch_2038	1.443e-84	287.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria,2YZQK@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5808221_1	502025.Hoch_3893	1.671e-181	573.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,2YUJZ@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome b subunit of the bc complex	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
CMS3_k127_5808221_8	502025.Hoch_3894	3.126e-60	213.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,42R5N@68525|delta/epsilon subdivisions,2X67B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS3_k127_5808221_9	502025.Hoch_3895	3.146e-48	175.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2X6N0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS3_k127_5808221_6	502025.Hoch_3897	2.659e-91	310.0	COG2267@1|root,COG2267@2|Bacteria,1QX85@1224|Proteobacteria,42W1M@68525|delta/epsilon subdivisions,2WR6V@28221|Deltaproteobacteria,2YUZN@29|Myxococcales	28221|Deltaproteobacteria	I	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
CMS3_k127_5808221_17	1125863.JAFN01000001_gene405	1.027e-11	79.0	COG3291@1|root,COG3291@2|Bacteria,1NM1Z@1224|Proteobacteria,42XEW@68525|delta/epsilon subdivisions,2WSVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5808221_0	404589.Anae109_1384	5.622e-213	679.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS3_k127_5808221_5	502025.Hoch_6795	1.485e-95	350.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_5808221_7	502025.Hoch_6795	1.774e-70	274.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_5808221_18	1192034.CAP_6943	4.623e-10	75.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
CMS3_k127_5808221_11	1120945.ATUW01000009_gene1052	8.047e-35	153.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4D3VG@85005|Actinomycetales	201174|Actinobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
CMS3_k127_5808221_3	502025.Hoch_3270	5.36e-152	488.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,2YUMG@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_5808221_2	502025.Hoch_3269	2.17e-168	537.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,2YTW5@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS3_k127_5808221_16	1304275.C41B8_08910	6.277e-22	113.0	COG2199@1|root,COG3706@2|Bacteria,1R3YY@1224|Proteobacteria,1RZ1W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GAF,GGDEF,PAS,PAS_8,PAS_9
CMS3_k127_5808221_10	309801.trd_1313	6.71e-39	168.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_5808221_4	502025.Hoch_3268	1.177e-101	337.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS3_k127_5808221_14	502025.Hoch_3267	5.274e-26	114.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2YVR1@29|Myxococcales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS3_k127_5808221_15	871968.DESME_12035	3.612e-25	109.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,260JZ@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_5811867_31	448385.sce0686	1.238e-13	84.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat
CMS3_k127_5811867_15	1254432.SCE1572_39310	4.561e-86	301.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1QA6R@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase
CMS3_k127_5811867_1	886293.Sinac_1156	2.507e-289	941.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5811867_6	215803.DB30_4888	4.147e-151	491.0	COG1858@1|root,COG1858@2|Bacteria,1PQCR@1224|Proteobacteria,437IU@68525|delta/epsilon subdivisions,2WYKN@28221|Deltaproteobacteria,2YZNB@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5811867_4	502025.Hoch_3844	2.173e-201	634.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2YUJM@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS3_k127_5811867_8	502025.Hoch_3843	6.252e-129	439.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2YUIU@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS3_k127_5811867_16	502025.Hoch_3841	1.909e-65	243.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria,2YV0G@29|Myxococcales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CMS3_k127_5811867_21	502025.Hoch_6704	1.413e-54	206.0	COG0745@1|root,COG0745@2|Bacteria	502025.Hoch_6704|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5811867_18	448385.sce4956	4.162e-56	214.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1QZX9@1224|Proteobacteria,42R2T@68525|delta/epsilon subdivisions,2WN6F@28221|Deltaproteobacteria,2Z39M@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_5811867_3	502025.Hoch_5556	2.372e-215	678.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2YTTF@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS3_k127_5811867_7	502025.Hoch_5555	5.493e-141	457.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,2YU17@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_5811867_13	502025.Hoch_5811	5.613e-103	355.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5811867_9	502025.Hoch_3976	9.728e-125	414.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	bcsC	-	1.8.1.9,2.7.11.1	ko:K00384,ko:K02453,ko:K11912,ko:K20543	ko00450,ko02025,ko03070,ko05111,map00450,map02025,map03070,map05111	M00331	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02044	1.B.55.3,3.A.15	-	-	BCSC_C,NfrA_C,TPR_16,TPR_19,TPR_8
CMS3_k127_5811867_2	502025.Hoch_3975	7.993e-244	764.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2YUAA@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_5811867_5	502025.Hoch_3974	1.836e-156	513.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YUSA@29|Myxococcales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS3_k127_5811867_29	1301100.HG529367_gene1345	4.854e-19	103.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,36DFY@31979|Clostridiaceae	186801|Clostridia	L	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
CMS3_k127_5811867_11	1254432.SCE1572_49150	1.74e-115	393.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria	1224|Proteobacteria	M	Spore Coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Cu-binding_MopE,Lectin_C
CMS3_k127_5811867_26	1123504.JQKD01000005_gene4773	6.993e-35	138.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,2VQZM@28216|Betaproteobacteria,4ADQK@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_5811867_14	502025.Hoch_3973	6.218e-92	309.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2YURX@29|Myxococcales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS3_k127_5811867_0	502025.Hoch_3972	0.0	1095.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2YUN3@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_5811867_27	502025.Hoch_3971	9.59e-33	139.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2YVZ7@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS3_k127_5811867_20	502025.Hoch_3970	1.287e-55	199.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2YVDF@29|Myxococcales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS3_k127_5811867_17	502025.Hoch_3969	7.123e-57	219.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_3969|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5811867_32	13035.Dacsa_3061	1.941e-11	74.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_5811867_25	886293.Sinac_1035	1.672e-39	163.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS3_k127_5811867_10	1192034.CAP_0930	9.264e-117	409.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria,2YWVC@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	HYR,VCBS
CMS3_k127_5811867_22	502025.Hoch_3968	3.189e-54	198.0	2A6Q2@1|root,30VI0@2|Bacteria,1QABI@1224|Proteobacteria,434YG@68525|delta/epsilon subdivisions,2X92X@28221|Deltaproteobacteria,2Z1MS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5811867_12	1254432.SCE1572_17640	2.132e-109	360.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5811867_23	635013.TherJR_2805	1.237e-51	205.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,267E8@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
CMS3_k127_5811867_24	1173024.KI912153_gene187	4.942e-43	179.0	COG0737@1|root,COG4894@1|root,COG0737@2|Bacteria,COG4894@2|Bacteria,1GBZ0@1117|Cyanobacteria,1JMFB@1189|Stigonemataceae	1117|Cyanobacteria	F	5'-nucleotidase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
CMS3_k127_5811867_35	7070.TC006293-PA	5.225e-05	54.0	2950X@1|root,2RBYN@2759|Eukaryota,38GI5@33154|Opisthokonta,3BGRR@33208|Metazoa,3CXES@33213|Bilateria	33208|Metazoa	S	UPF0764 protein C16orf89 homolog	C16orf89	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016020,GO:0042802,GO:0042803,GO:0044424,GO:0044444,GO:0044464,GO:0046983	-	-	-	-	-	-	-	-	-	-	DUF4735
CMS3_k127_5811867_19	1192034.CAP_1238	9.177e-56	216.0	COG4733@1|root,COG4935@1|root,COG5184@1|root,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2Z3N3@29|Myxococcales	28221|Deltaproteobacteria	DOZ	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
CMS3_k127_5818760_1	935948.KE386495_gene1578	1.282e-268	837.0	COG1274@1|root,COG1274@2|Bacteria,1TQED@1239|Firmicutes,249NP@186801|Clostridia,42FYF@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CMS3_k127_5818760_8	502025.Hoch_3385	2.82e-95	327.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,2YUWI@29|Myxococcales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_5818760_12	1123366.TH3_07127	7.325e-54	201.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,2TRJH@28211|Alphaproteobacteria,2JZAC@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
CMS3_k127_5818760_11	502025.Hoch_3384	1.504e-66	242.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	CarboxypepD_reg,PD40
CMS3_k127_5818760_17	502025.Hoch_3437	9.354e-35	144.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS3_k127_5818760_15	1254432.SCE1572_07095	2.605e-39	162.0	28IX1@1|root,2Z8V3@2|Bacteria,1N0WD@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
CMS3_k127_5818760_2	502025.Hoch_1779	7.203e-205	645.0	COG0436@1|root,COG0436@2|Bacteria,1QHKS@1224|Proteobacteria,42Z0T@68525|delta/epsilon subdivisions,2WU4I@28221|Deltaproteobacteria,2YTVA@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_5818760_9	502025.Hoch_6483	5.766e-81	278.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,2YVD8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS3_k127_5818760_7	502025.Hoch_6482	1.409e-95	340.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
CMS3_k127_5818760_3	471223.GWCH70_0033	1.081e-185	612.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1WEZ0@129337|Geobacillus	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS3_k127_5818760_13	502025.Hoch_0469	5.665e-51	203.0	COG1413@1|root,COG1413@2|Bacteria,1QAW1@1224|Proteobacteria,43E4E@68525|delta/epsilon subdivisions,2WZPH@28221|Deltaproteobacteria,2Z2H1@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_5818760_5	502025.Hoch_0468	4.084e-103	351.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2YUWH@29|Myxococcales	28221|Deltaproteobacteria	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS3_k127_5818760_6	502025.Hoch_6721	2.099e-98	326.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2YV8C@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS3_k127_5818760_10	502025.Hoch_6720	3.48e-78	265.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,42T4F@68525|delta/epsilon subdivisions,2WP6B@28221|Deltaproteobacteria,2YVEY@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS3_k127_5818760_14	502025.Hoch_6719	1.453e-50	201.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2YVAC@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
CMS3_k127_5818760_4	502025.Hoch_0237	3.093e-163	549.0	COG0457@1|root,COG0457@2|Bacteria,1NEMW@1224|Proteobacteria,42WBX@68525|delta/epsilon subdivisions,2WRAD@28221|Deltaproteobacteria,2YXW6@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_8
CMS3_k127_5818760_0	502025.Hoch_4111	3.912e-280	876.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2YUGE@29|Myxococcales	28221|Deltaproteobacteria	J	Elongation factor G, domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_5841419_7	502025.Hoch_4569	1.588e-80	284.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5841419_2	502025.Hoch_3669	3.026e-199	629.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_5841419_4	502025.Hoch_3670	3.589e-112	381.0	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5841419_0	1254432.SCE1572_45180	3.094e-233	744.0	COG0574@1|root,COG0574@2|Bacteria,1P35R@1224|Proteobacteria,4340K@68525|delta/epsilon subdivisions,2X4FG@28221|Deltaproteobacteria,2YYX6@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
CMS3_k127_5841419_14	983917.RGE_30040	7.046e-50	199.0	COG3837@1|root,COG3837@2|Bacteria,1PR0G@1224|Proteobacteria,2WBKD@28216|Betaproteobacteria,1KP4X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_5841419_10	1121272.KB903283_gene4935	2.071e-70	246.0	COG1733@1|root,COG1733@2|Bacteria,2I9HE@201174|Actinobacteria,4DIGA@85008|Micromonosporales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS3_k127_5841419_6	1089551.KE386572_gene2233	7.371e-95	317.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,4BSGF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_5841419_15	1296415.JACC01000063_gene3908	4.197e-46	186.0	28HH2@1|root,33750@2|Bacteria,4NXNM@976|Bacteroidetes,1IIC1@117743|Flavobacteriia	976|Bacteroidetes	M	Thiol-activated cytolysin	-	-	-	ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	Thiol_cytolysin
CMS3_k127_5841419_23	502025.Hoch_6029	2.688e-16	93.0	COG0810@1|root,COG0810@2|Bacteria,1PBUV@1224|Proteobacteria,4384F@68525|delta/epsilon subdivisions,2X9X5@28221|Deltaproteobacteria,2YVPR@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	-
CMS3_k127_5841419_19	448385.sce0418	1.765e-39	163.0	2ANIU@1|root,31DHW@2|Bacteria,1QATB@1224|Proteobacteria,435AE@68525|delta/epsilon subdivisions,2WZMG@28221|Deltaproteobacteria,2Z2DG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5841419_26	643562.Daes_2941	1.775e-06	51.0	2EIZA@1|root,33CQH@2|Bacteria,1NJDM@1224|Proteobacteria,42WT9@68525|delta/epsilon subdivisions,2WT1N@28221|Deltaproteobacteria,2ME4V@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
CMS3_k127_5841419_11	483219.LILAB_20575	9.721e-59	219.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
CMS3_k127_5841419_8	1300345.LF41_438	6.228e-79	272.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1X41P@135614|Xanthomonadales	135614|Xanthomonadales	KT	XRE family transcriptional regulator	VL23_03445	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5841419_12	177437.HRM2_03410	3.44e-58	214.0	COG0642@1|root,COG0642@2|Bacteria,1R514@1224|Proteobacteria,43AF9@68525|delta/epsilon subdivisions,2X5V0@28221|Deltaproteobacteria,2MK27@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_5841419_9	237368.SCABRO_01266	1.561e-73	266.0	COG0079@1|root,COG0079@2|Bacteria	2|Bacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5841419_5	502025.Hoch_5425	2.673e-95	317.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2Z0YN@29|Myxococcales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_5841419_21	7739.XP_002606139.1	2.298e-27	126.0	KOG1216@1|root,KOG1217@1|root,KOG1216@2759|Eukaryota,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,48CY1@7711|Chordata	33208|Metazoa	T	EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_3,EGF_CA,Lectin_C,TIL
CMS3_k127_5841419_18	502025.Hoch_1530	1.784e-41	169.0	COG3203@1|root,COG3203@2|Bacteria,1QVA0@1224|Proteobacteria,42P8X@68525|delta/epsilon subdivisions,2WM47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,FG-GAP_2
CMS3_k127_5841419_13	502025.Hoch_1530	2.121e-57	218.0	COG3203@1|root,COG3203@2|Bacteria,1QVA0@1224|Proteobacteria,42P8X@68525|delta/epsilon subdivisions,2WM47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,FG-GAP_2
CMS3_k127_5841419_22	502025.Hoch_0386	4.101e-17	91.0	COG0500@1|root,COG2226@2|Bacteria,1QA2K@1224|Proteobacteria,43DX6@68525|delta/epsilon subdivisions,2WZ3U@28221|Deltaproteobacteria,2Z19N@29|Myxococcales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_5841419_3	448385.sce3735	3.06e-163	520.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_5841419_1	290397.Adeh_2071	1.098e-223	703.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_5859194_0	83406.HDN1F_10410	1.813e-178	567.0	COG1960@1|root,COG1960@2|Bacteria,1R81V@1224|Proteobacteria,1SM92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5859668_2	419947.MRA_1846	1.48e-125	416.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,235H0@1762|Mycobacteriaceae	201174|Actinobacteria	S	peptidase S15	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_5859668_4	502025.Hoch_6401	1.77e-62	227.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	ko:K03496,ko:K22491	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	B12-binding_2,DUF3967,HTH_17,MerR_1
CMS3_k127_5859668_3	1121430.JMLG01000002_gene1059	7.302e-81	288.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia,263EX@186807|Peptococcaceae	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_5859668_8	42256.RradSPS_0393	1.518e-30	134.0	COG5424@1|root,COG5424@2|Bacteria	2|Bacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	-	-	1.3.3.11,2.6.1.76	ko:K00836,ko:K06137	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Cupin_2,Haem_oxygenas_2
CMS3_k127_5859668_5	502025.Hoch_5432	1.092e-56	202.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,42U6P@68525|delta/epsilon subdivisions,2WQ00@28221|Deltaproteobacteria,2YVG1@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS3_k127_5859668_1	502025.Hoch_6281	3.021e-126	422.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
CMS3_k127_5859668_0	502025.Hoch_6280	1.898e-129	429.0	COG3005@1|root,COG3005@2|Bacteria,1R03H@1224|Proteobacteria,43CQK@68525|delta/epsilon subdivisions,2X7Y1@28221|Deltaproteobacteria,2Z1GR@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_5860037_5	502025.Hoch_5954	3.173e-71	254.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,42NNW@68525|delta/epsilon subdivisions,2WMWA@28221|Deltaproteobacteria,2YVKG@29|Myxococcales	28221|Deltaproteobacteria	GM	ABC transporter	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_5860037_4	502025.Hoch_5955	2.398e-77	266.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42SZT@68525|delta/epsilon subdivisions,2WPTX@28221|Deltaproteobacteria,2YZ9V@29|Myxococcales	28221|Deltaproteobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09688,ko:K09690	ko02010,map02010	M00249,M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.101,3.A.1.103	-	-	ABC2_membrane
CMS3_k127_5860037_2	314278.NB231_02843	1.031e-96	327.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1WWFJ@135613|Chromatiales	135613|Chromatiales	M	Arabinose 5-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,SIS
CMS3_k127_5860037_7	404589.Anae109_3900	3.425e-62	226.0	2EGEF@1|root,33A6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5860037_12	502025.Hoch_5446	7.737e-13	80.0	COG1366@1|root,COG1366@2|Bacteria,1NG3I@1224|Proteobacteria,42W69@68525|delta/epsilon subdivisions,2WS39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5860037_14	502025.Hoch_1932	3.716e-09	66.0	2A7EC@1|root,30WBT@2|Bacteria,1PDJ7@1224|Proteobacteria,43E64@68525|delta/epsilon subdivisions,2WZUI@28221|Deltaproteobacteria,2Z2SD@29|Myxococcales	28221|Deltaproteobacteria	S	Copper binding periplasmic protein CusF	-	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
CMS3_k127_5860037_0	439235.Dalk_2721	1.644e-100	345.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2MJ0P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_5860037_15	448385.sce2249	8.804e-09	69.0	COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,4313T@68525|delta/epsilon subdivisions,2WWBJ@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_5860037_11	1242864.D187_004270	3.679e-17	96.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5860037_3	1278073.MYSTI_06621	9.662e-83	294.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,439QP@68525|delta/epsilon subdivisions,2X537@28221|Deltaproteobacteria,2Z01T@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix domain	dpbF	-	-	-	-	-	-	-	-	-	-	-	HHH_5,HHH_8
CMS3_k127_5860037_16	1254432.SCE1572_18895	1.306e-07	64.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	DUF4214,SBBP,TPR_19
CMS3_k127_5860037_1	1254432.SCE1572_45120	2.25e-99	360.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_5860037_8	1229172.JQFA01000002_gene4296	6.909e-61	226.0	COG2114@1|root,COG2114@2|Bacteria,1GCNK@1117|Cyanobacteria,1HDZQ@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_5860037_6	195250.CM001776_gene4045	3.781e-69	246.0	COG1215@1|root,COG1215@2|Bacteria,1GMST@1117|Cyanobacteria,1H0CG@1129|Synechococcus	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5860037_10	596151.DesfrDRAFT_2459	4.231e-42	174.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_587665_0	1232410.KI421425_gene1553	9.045e-243	772.0	COG4932@1|root,COG4932@2|Bacteria,1QZFW@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS3_k127_5898744_2	502025.Hoch_2388	1.668e-48	178.0	2AYUN@1|root,31R03@2|Bacteria,1QNIW@1224|Proteobacteria,43861@68525|delta/epsilon subdivisions,2X3FV@28221|Deltaproteobacteria,2YVX4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5898744_3	1500893.JQNB01000001_gene17	8.638e-22	110.0	2CA5V@1|root,2Z9I7@2|Bacteria,1R50M@1224|Proteobacteria,1THFK@1236|Gammaproteobacteria,1X4JB@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5898744_0	344747.PM8797T_09984	1.553e-77	291.0	COG3829@1|root,COG3829@2|Bacteria,2J53D@203682|Planctomycetes	203682|Planctomycetes	KT	Two component, sigma54 specific, transcriptional regulator, Fis family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS3_k127_5898744_4	691883.XP_009498109.1	0.0007249	51.0	COG1404@1|root,KOG0595@1|root,KOG0595@2759|Eukaryota,KOG3525@2759|Eukaryota,38EIV@33154|Opisthokonta	33154|Opisthokonta	OT	extracellular matrix	FRAS1	GO:0001655,GO:0001656,GO:0001822,GO:0002009,GO:0003338,GO:0005575,GO:0005576,GO:0005604,GO:0006810,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0015031,GO:0015833,GO:0030326,GO:0031012,GO:0032501,GO:0032502,GO:0033036,GO:0035107,GO:0035108,GO:0035113,GO:0042886,GO:0043588,GO:0044420,GO:0044421,GO:0045184,GO:0048513,GO:0048598,GO:0048729,GO:0048731,GO:0048736,GO:0048856,GO:0051179,GO:0051234,GO:0060021,GO:0060173,GO:0060429,GO:0060993,GO:0061618,GO:0062023,GO:0071702,GO:0071705,GO:0072001	-	ko:K17885	-	-	-	-	ko00000,ko02000,ko03029	2.A.29.25	-	-	Cadherin_3,Calx-beta,Pkinase,VWC
CMS3_k127_5898744_1	502025.Hoch_3601	6.776e-57	205.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2X5NA@28221|Deltaproteobacteria,2Z36H@29|Myxococcales	28221|Deltaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_5900100_7	502025.Hoch_5698	7.076e-53	205.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_5698|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900100_8	204669.Acid345_1475	2.59e-35	149.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_5900100_5	502025.Hoch_5699	5.116e-61	228.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_5699|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900100_4	502025.Hoch_6562	4.281e-76	260.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2X2RV@28221|Deltaproteobacteria,2YW4J@29|Myxococcales	28221|Deltaproteobacteria	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS3_k127_5900100_2	292459.STH1727	3.353e-88	303.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
CMS3_k127_5900100_10	1254432.SCE1572_39595	1.51e-23	113.0	2AGUQ@1|root,31732@2|Bacteria,1PYBC@1224|Proteobacteria,43E2X@68525|delta/epsilon subdivisions,2WZJA@28221|Deltaproteobacteria,2Z299@29|Myxococcales	28221|Deltaproteobacteria	S	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_5900100_1	583355.Caka_2769	2.732e-113	383.0	COG0635@1|root,COG0635@2|Bacteria,46TQX@74201|Verrucomicrobia,3K7DD@414999|Opitutae	414999|Opitutae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS3_k127_5900100_6	502025.Hoch_4101	6.06e-60	215.0	COG0664@1|root,COG0664@2|Bacteria,1QAZ0@1224|Proteobacteria,43E4R@68525|delta/epsilon subdivisions,2WZQH@28221|Deltaproteobacteria,2Z2IM@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_5900100_12	266117.Rxyl_0937	8.125e-11	71.0	COG0517@1|root,COG0517@2|Bacteria,2GSAR@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
CMS3_k127_5900100_0	1229780.BN381_290075	3.069e-126	410.0	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Ald_deCOase
CMS3_k127_5900100_3	502025.Hoch_5367	3.277e-77	261.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_5900122_1	1122951.ATUE01000006_gene1299	1.852e-56	211.0	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1T2C6@1236|Gammaproteobacteria,3NKZE@468|Moraxellaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS3_k127_5900122_0	502025.Hoch_6589	1.218e-79	268.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_5904046_0	1192034.CAP_7388	2.844e-242	771.0	COG0366@1|root,COG0535@1|root,COG0366@2|Bacteria,COG0535@2|Bacteria,1NJ3W@1224|Proteobacteria,42PQJ@68525|delta/epsilon subdivisions,2WKAV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
CMS3_k127_5904046_4	1172188.KB911821_gene1734	3.862e-17	96.0	COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4FF9Y@85021|Intrasporangiaceae	201174|Actinobacteria	S	Metal-dependent phosphoesterase	PPA1328	-	3.1.3.97,3.1.4.57	ko:K07053,ko:K20859	ko00440,map00440	-	R00188,R10972,R10973,R11188	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	PHP
CMS3_k127_5904046_2	502025.Hoch_5811	7.309e-100	345.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5904046_1	1144275.COCOR_00733	2.036e-112	391.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
CMS3_k127_5905030_0	398720.MED217_05937	2.037e-124	419.0	COG3693@1|root,COG3693@2|Bacteria,4PMHJ@976|Bacteroidetes,1IMUF@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS3_k127_5905030_2	448385.sce7917	1.52e-83	309.0	COG1388@1|root,COG3770@1|root,COG1388@2|Bacteria,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,42VK7@68525|delta/epsilon subdivisions,2WS1M@28221|Deltaproteobacteria,2YVMA@29|Myxococcales	28221|Deltaproteobacteria	M	LysM domain protein	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M74
CMS3_k127_5905030_7	502025.Hoch_5791	1.873e-46	179.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GerE,Yop-YscD_cpl
CMS3_k127_5905030_3	502025.Hoch_4058	1.373e-63	230.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YYKD@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_5905030_1	502025.Hoch_4058	8.887e-106	374.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YYKD@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_5905030_5	525904.Tter_2578	6.895e-59	214.0	COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_5905030_6	266117.Rxyl_0438	3.641e-50	196.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CMS3_k127_5905030_10	502025.Hoch_5387	3.935e-17	82.0	2AGJK@1|root,316SP@2|Bacteria,1PXYX@1224|Proteobacteria,434YM@68525|delta/epsilon subdivisions,2WZ9F@28221|Deltaproteobacteria,2Z1MY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5905030_4	1288826.MSNKSG1_11883	3.313e-63	226.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,467FG@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS3_k127_5905030_9	134676.ACPL_7501	5.207e-41	160.0	COG0515@1|root,COG0515@2|Bacteria,2IB91@201174|Actinobacteria,4D9FG@85008|Micromonosporales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_5909997_5	502025.Hoch_0259	3.078e-55	200.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GerE
CMS3_k127_5909997_4	502025.Hoch_0200	3.361e-94	345.0	COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,42XHB@68525|delta/epsilon subdivisions,2WSKY@28221|Deltaproteobacteria,2YVC2@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_5909997_1	502025.Hoch_5811	1.957e-101	362.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5909997_7	1298863.AUEP01000004_gene2094	2.146e-27	123.0	2EVIQ@1|root,33NYW@2|Bacteria,2IIIZ@201174|Actinobacteria,4DUAA@85009|Propionibacteriales	201174|Actinobacteria	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
CMS3_k127_5909997_0	886293.Sinac_1156	4.699e-283	913.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5909997_6	502025.Hoch_2840	1.815e-48	195.0	COG0500@1|root,COG2226@2|Bacteria,1PEJ8@1224|Proteobacteria,43148@68525|delta/epsilon subdivisions,2WX1D@28221|Deltaproteobacteria,2YV36@29|Myxococcales	28221|Deltaproteobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_5909997_3	760192.Halhy_3817	1.892e-98	332.0	COG1237@1|root,COG1237@2|Bacteria,4PJ4J@976|Bacteroidetes,1IZIT@117747|Sphingobacteriia	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_5909997_2	497964.CfE428DRAFT_1688	1.18e-98	347.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
CMS3_k127_5909997_8	7739.XP_002601494.1	5.117e-10	71.0	KOG1217@1|root,KOG1217@2759|Eukaryota,3AH1R@33154|Opisthokonta,3BWTW@33208|Metazoa,3DEM0@33213|Bilateria,48RN8@7711|Chordata	33208|Metazoa	T	Mucin 4, cell surface associated	MUC4	-	-	ko:K22017	-	-	-	-	ko00000,ko04131	-	-	-	AMOP,EGF,EGF_3,EGF_CA,NIDO,VWD,hEGF
CMS3_k127_591287_23	290397.Adeh_0078	3.712e-07	55.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_591287_0	1121904.ARBP01000007_gene2888	3.727e-234	773.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,47MF6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_591287_8	502025.Hoch_3466	1.617e-116	404.0	2DWMJ@1|root,3410X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_591287_12	502025.Hoch_3468	4.73e-82	290.0	COG1716@1|root,COG1716@2|Bacteria,1QH9U@1224|Proteobacteria,434RS@68525|delta/epsilon subdivisions,2WZ2V@28221|Deltaproteobacteria,2Z17M@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_591287_13	502025.Hoch_3469	1.614e-81	283.0	COG0631@1|root,COG0631@2|Bacteria,1NCRX@1224|Proteobacteria,43ABC@68525|delta/epsilon subdivisions,2X2PV@28221|Deltaproteobacteria,2Z0FJ@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_591287_20	448385.sce2038	1.389e-40	173.0	COG1716@1|root,COG3591@1|root,COG1716@2|Bacteria,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	3.2.1.14	ko:K01183,ko:K03791	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18,GH19	-	Trypsin,Trypsin_2
CMS3_k127_591287_3	502025.Hoch_3472	1.008e-144	471.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439KJ@68525|delta/epsilon subdivisions,2X4XC@28221|Deltaproteobacteria,2Z096@29|Myxococcales	28221|Deltaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_591287_4	502025.Hoch_3473	3.383e-137	464.0	COG3049@1|root,COG3049@2|Bacteria,1RHU2@1224|Proteobacteria,42XVE@68525|delta/epsilon subdivisions,2WT93@28221|Deltaproteobacteria,2YW4E@29|Myxococcales	28221|Deltaproteobacteria	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_591287_24	247490.KSU1_D0432	2.614e-05	54.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_591287_21	391625.PPSIR1_11405	3.826e-25	116.0	COG0695@1|root,COG0695@2|Bacteria,1PPNM@1224|Proteobacteria,437CJ@68525|delta/epsilon subdivisions,2X2I6@28221|Deltaproteobacteria,2Z2DY@29|Myxococcales	28221|Deltaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS3_k127_591287_7	502025.Hoch_3272	2.259e-126	418.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2Z30T@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS3_k127_591287_9	1232410.KI421418_gene2304	9.399e-114	377.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,43SBV@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS3_k127_591287_6	502025.Hoch_3273	6.498e-127	418.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_591287_5	502025.Hoch_3576	1.532e-136	447.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,2YUM6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS3_k127_591287_16	251221.35214856	2.504e-55	203.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
CMS3_k127_591287_15	1223521.BBJX01000018_gene643	3.608e-56	203.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,4ABWJ@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS3_k127_591287_17	1297581.H919_01040	8.091e-54	200.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,4HG4T@91061|Bacilli,21WXP@150247|Anoxybacillus	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS3_k127_591287_19	765869.BDW_06770	1.026e-41	158.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2MUST@213481|Bdellovibrionales,2WPPE@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_591287_11	502025.Hoch_3692	1.716e-86	301.0	COG0354@1|root,COG0354@2|Bacteria,1QYGE@1224|Proteobacteria,43CCJ@68525|delta/epsilon subdivisions,2WYDB@28221|Deltaproteobacteria,2Z3H2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
CMS3_k127_591287_1	502025.Hoch_3695	8.262e-233	757.0	COG4775@1|root,COG4775@2|Bacteria,1R75N@1224|Proteobacteria,42MIG@68525|delta/epsilon subdivisions,2WMI0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_591287_2	502025.Hoch_3696	4.036e-213	716.0	COG2911@1|root,COG2911@2|Bacteria,1Q9EY@1224|Proteobacteria,4377C@68525|delta/epsilon subdivisions,2X287@28221|Deltaproteobacteria,2Z2EJ@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:DUF490	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS3_k127_591287_22	620914.JH621253_gene2580	1.251e-21	105.0	COG5384@1|root,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes,1IJ9Q@117743|Flavobacteriia	976|Bacteroidetes	JQ	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,TSP_3
CMS3_k127_5918568_10	1298863.AUEP01000007_gene409	3.447e-15	76.0	COG1028@1|root,COG1028@2|Bacteria,2HRAZ@201174|Actinobacteria,4DQ01@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_5918568_3	479432.Sros_2067	1.707e-125	407.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4EI03@85012|Streptosporangiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5918568_4	1137799.GZ78_07265	1.844e-112	382.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,1RYCC@1236|Gammaproteobacteria,1XRGZ@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_5918568_1	43759.JNWK01000016_gene312	1.179e-159	529.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE30	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5918568_6	1229780.BN381_430049	8.011e-72	270.0	COG0596@1|root,COG0596@2|Bacteria,2I9EI@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_5918568_0	502025.Hoch_1373	3.81e-255	825.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,438BA@68525|delta/epsilon subdivisions,2X3KK@28221|Deltaproteobacteria,2YWFN@29|Myxococcales	28221|Deltaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS3_k127_5918568_9	240292.Ava_2167	3.625e-43	180.0	COG2335@1|root,COG2335@2|Bacteria,1G5TY@1117|Cyanobacteria,1HNEC@1161|Nostocales	1117|Cyanobacteria	M	COGs COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS3_k127_5918568_2	489825.LYNGBM3L_63840	1.3e-127	453.0	COG4320@1|root,COG4320@2|Bacteria,1G2CN@1117|Cyanobacteria,1H7R5@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
CMS3_k127_5918568_7	420324.KI911950_gene7039	7.16e-44	183.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_5918568_5	622637.KE124774_gene2837	6.869e-104	355.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,36ZVX@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_592481_13	378806.STAUR_7364	6.129e-69	239.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria,2YXV7@29|Myxococcales	28221|Deltaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
CMS3_k127_592481_17	710696.Intca_0794	9.768e-47	174.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4FF9T@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG3464 Transposase and inactivated derivatives	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
CMS3_k127_592481_25	1144275.COCOR_01519	1.997e-07	64.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_592481_10	886293.Sinac_4113	1.569e-76	269.0	COG4977@1|root,COG4977@2|Bacteria,2IXH9@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	ko:K17736	-	-	-	-	ko00000,ko03000	-	-	-	DJ-1_PfpI,HTH_18
CMS3_k127_592481_11	622637.KE124774_gene479	4.469e-73	261.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2U0CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
CMS3_k127_592481_23	760192.Halhy_3107	1.112e-16	89.0	2AC8D@1|root,311T2@2|Bacteria,4NXA6@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_592481_20	420324.KI911973_gene3066	9.404e-24	106.0	COG3039@1|root,COG3039@2|Bacteria,1RAFC@1224|Proteobacteria,2VGSG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	IS5 family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_5
CMS3_k127_592481_22	880073.Calab_3278	1.622e-17	87.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
CMS3_k127_592481_19	502025.Hoch_1576	1.041e-24	109.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_592481_0	1499967.BAYZ01000061_gene5928	3.041e-267	843.0	COG2759@1|root,COG2759@2|Bacteria,2NP2R@2323|unclassified Bacteria	2|Bacteria	F	Formate--tetrahydrofolate ligase	fhs	GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
CMS3_k127_592481_3	573413.Spirs_2429	2.484e-133	431.0	COG0190@1|root,COG0190@2|Bacteria,2J5PR@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS3_k127_592481_1	96561.Dole_1516	1.862e-191	623.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MI2I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS3_k127_592481_16	1161401.ASJA01000003_gene2857	9.157e-49	192.0	COG1680@1|root,COG1680@2|Bacteria,1QJH7@1224|Proteobacteria,2VFCQ@28211|Alphaproteobacteria,44130@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_592481_26	1458427.BAWN01000094_gene2212	2.72e-06	54.0	COG0399@1|root,COG4448@1|root,COG0399@2|Bacteria,COG4448@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
CMS3_k127_592481_9	251221.35214774	2.081e-85	321.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
CMS3_k127_592481_24	886293.Sinac_7318	5.778e-09	65.0	COG1595@1|root,COG1595@2|Bacteria,2J0K1@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
CMS3_k127_592481_12	886293.Sinac_7479	1.558e-71	275.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_592481_4	1125863.JAFN01000001_gene1617	3.634e-130	440.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS3_k127_592481_7	1380390.JIAT01000014_gene6241	9.028e-91	309.0	COG4948@1|root,COG4948@2|Bacteria,2I7AE@201174|Actinobacteria,4CPIJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_592481_14	929703.KE386491_gene2333	2.589e-57	227.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_592481_5	554065.XP_005847687.1	4.763e-124	425.0	COG1070@1|root,KOG2531@2759|Eukaryota,37N8F@33090|Viridiplantae,34HBU@3041|Chlorophyta	3041|Chlorophyta	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS3_k127_592481_2	1128421.JAGA01000002_gene1087	8.718e-163	522.0	COG2115@1|root,COG2115@2|Bacteria,2NQDI@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_592481_6	552811.Dehly_1170	2.687e-107	360.0	COG0501@1|root,COG0501@2|Bacteria,2G6UV@200795|Chloroflexi,34D0W@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS3_k127_592481_15	661478.OP10G_3719	1.124e-53	202.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS3_k127_592481_21	945713.IALB_2435	3.097e-18	90.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
CMS3_k127_592481_8	756272.Plabr_2714	4.277e-88	297.0	COG2755@1|root,COG2755@2|Bacteria,2J37I@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_592481_18	906888.JCM19314_531	5.41e-41	157.0	COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,1I30K@117743|Flavobacteriia,3HKGJ@363408|Nonlabens	976|Bacteroidetes	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_5925701_2	648885.KB316283_gene2809	1.84e-116	396.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,1JS8T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_5925701_4	1355374.JARU01000001_gene618	3.384e-18	98.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42NNF@68525|delta/epsilon subdivisions,2YTMC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS3_k127_5925701_5	1077144.AGFF01000012_gene2572	0.0007743	49.0	COG1933@1|root,COG1933@2|Bacteria,2GTA2@201174|Actinobacteria	201174|Actinobacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5925701_1	502025.Hoch_5121	4.076e-126	419.0	COG2304@1|root,COG2304@2|Bacteria,1REJW@1224|Proteobacteria,43BIH@68525|delta/epsilon subdivisions,2X6WV@28221|Deltaproteobacteria,2YVF8@29|Myxococcales	28221|Deltaproteobacteria	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_5925701_0	502025.Hoch_2750	3.024e-226	721.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2YUGB@29|Myxococcales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.3.4.14,6.3.4.6,6.4.1.2	ko:K01941,ko:K01961	ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R00774,R04385	RC00040,RC00253,RC00367,RC00378	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS3_k127_5925701_3	292459.STH3142	3.832e-26	113.0	COG4231@1|root,COG4231@2|Bacteria,1VIY6@1239|Firmicutes,24PDQ@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS3_k127_5927505_8	1192034.CAP_2899	1.266e-36	160.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2WM39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5927505_6	391625.PPSIR1_21719	7.044e-48	190.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CMS3_k127_5927505_4	502025.Hoch_3245	1.349e-72	251.0	COG4122@1|root,COG4122@2|Bacteria,1R4VI@1224|Proteobacteria,42VVN@68525|delta/epsilon subdivisions,2WRTH@28221|Deltaproteobacteria,2YVK4@29|Myxococcales	28221|Deltaproteobacteria	S	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
CMS3_k127_5927505_5	215803.DB30_1747	2.64e-53	206.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	MA20_04930	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS3_k127_5927505_1	1254432.SCE1572_45120	1.7e-122	431.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_5927505_0	448385.sce4588	4.96e-138	455.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
CMS3_k127_5927505_3	1297742.A176_04476	2.311e-101	363.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_5927505_2	502025.Hoch_0120	4.386e-119	414.0	COG5107@1|root,COG5107@2|Bacteria	2|Bacteria	A	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
CMS3_k127_5927505_7	243090.RB6432	1.384e-46	178.0	COG2010@1|root,COG2755@1|root,COG5297@1|root,COG2010@2|Bacteria,COG2755@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Alginate_lyase2,Lipase_GDSL_2
CMS3_k127_5927505_11	1048339.KB913029_gene270	0.0001134	46.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4EWAG@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_5928672_0	1449357.JQLK01000001_gene1286	0.0	1155.0	COG5013@1|root,COG5013@2|Bacteria,1WJC1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
CMS3_k127_5928672_5	575540.Isop_2491	5.955e-107	364.0	COG2204@1|root,COG2204@2|Bacteria,2IYHI@203682|Planctomycetes	203682|Planctomycetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5928672_10	644282.Deba_3291	1.281e-44	181.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GerE,HATPase_c,HisKA
CMS3_k127_5928672_18	290397.Adeh_1321	3.264e-19	93.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5928672_19	1122603.ATVI01000005_gene2888	5.823e-08	60.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_5928672_11	502025.Hoch_1336	1.681e-38	162.0	COG0457@1|root,COG0457@2|Bacteria,1Q2MK@1224|Proteobacteria,43886@68525|delta/epsilon subdivisions,2X3HX@28221|Deltaproteobacteria,2YW6E@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5928672_8	439235.Dalk_3834	1.414e-58	228.0	COG1960@1|root,COG1960@2|Bacteria,1R59X@1224|Proteobacteria,42P22@68525|delta/epsilon subdivisions,2WKQN@28221|Deltaproteobacteria,2MJCR@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5928672_17	378806.STAUR_6633	6.513e-24	111.0	COG4689@1|root,COG4689@2|Bacteria,1R7YD@1224|Proteobacteria,42XRR@68525|delta/epsilon subdivisions,2WTD1@28221|Deltaproteobacteria,2YY3B@29|Myxococcales	28221|Deltaproteobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
CMS3_k127_5928672_15	1232410.KI421421_gene3250	4.344e-28	129.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_5928672_7	85643.Tmz1t_2948	4.681e-86	312.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,2VSQQ@28216|Betaproteobacteria,2KXX8@206389|Rhodocyclales	206389|Rhodocyclales	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
CMS3_k127_5928672_4	1232410.KI421421_gene3272	1.594e-133	458.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2X5NK@28221|Deltaproteobacteria,43W2S@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS3_k127_5928672_1	1187851.A33M_3197	2.41e-198	625.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_5928672_2	1232410.KI421421_gene3270	2.474e-150	484.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_5928672_14	671143.DAMO_1385	9.351e-34	150.0	COG0731@1|root,COG0731@2|Bacteria,2NR61@2323|unclassified Bacteria	2|Bacteria	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_5928672_12	1278073.MYSTI_01631	4.291e-38	158.0	2BRHH@1|root,32KGG@2|Bacteria,1Q2UB@1224|Proteobacteria,438GJ@68525|delta/epsilon subdivisions,2X21P@28221|Deltaproteobacteria,2YWXE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5928672_6	378806.STAUR_1603	2.945e-95	333.0	29NRY@1|root,309PY@2|Bacteria,1QT0E@1224|Proteobacteria,438CE@68525|delta/epsilon subdivisions,2X3MR@28221|Deltaproteobacteria,2YWJ7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5928672_22	1254432.SCE1572_17060	0.0007891	51.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,42NMF@68525|delta/epsilon subdivisions,2WIJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS3_k127_5928672_16	1254432.SCE1572_32105	5.85e-24	106.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WRIB@28221|Deltaproteobacteria,2YVSI@29|Myxococcales	28221|Deltaproteobacteria	S	CBS domain	-	-	-	ko:K04767,ko:K07168,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_5928672_13	502025.Hoch_5234	5.728e-34	132.0	2E4KV@1|root,32ZFU@2|Bacteria,1NPD5@1224|Proteobacteria,42XQS@68525|delta/epsilon subdivisions,2WTAP@28221|Deltaproteobacteria,2YVXV@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
CMS3_k127_5928672_3	502025.Hoch_5958	9.079e-140	471.0	COG0457@1|root,COG0457@2|Bacteria,1PC8F@1224|Proteobacteria,438AR@68525|delta/epsilon subdivisions,2X3K3@28221|Deltaproteobacteria,2YWDI@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS3_k127_5940643_2	1254432.SCE1572_51745	8.37e-80	293.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_5940643_1	1123508.JH636440_gene2902	1.238e-97	361.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_5940643_0	82654.Pse7367_0584	2.577e-162	540.0	COG2304@1|root,COG2304@2|Bacteria,1GQAG@1117|Cyanobacteria,1H979@1150|Oscillatoriales	1117|Cyanobacteria	T	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_5948107_8	742738.HMPREF9460_00780	5.406e-06	57.0	COG3064@1|root,COG3064@2|Bacteria,1VB1V@1239|Firmicutes,24BPB@186801|Clostridia,269DK@186813|unclassified Clostridiales	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5948107_4	1179773.BN6_28070	1.716e-34	136.0	COG0346@1|root,COG1865@1|root,COG0346@2|Bacteria,COG1865@2|Bacteria,2II17@201174|Actinobacteria,4E6CD@85010|Pseudonocardiales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_5948107_3	502025.Hoch_5414	9.742e-78	271.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,42PYC@68525|delta/epsilon subdivisions,2WMC4@28221|Deltaproteobacteria,2YUJR@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_5948107_0	1254432.SCE1572_22680	1.137e-161	523.0	COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,43347@68525|delta/epsilon subdivisions,2X4FK@28221|Deltaproteobacteria,2YYXB@29|Myxococcales	28221|Deltaproteobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
CMS3_k127_5948107_6	1122611.KB903967_gene5140	6.123e-19	94.0	COG1309@1|root,COG1309@2|Bacteria,2I16R@201174|Actinobacteria,4EM5K@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5948107_2	502025.Hoch_1524	1.259e-95	339.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,437RI@68525|delta/epsilon subdivisions,2X30A@28221|Deltaproteobacteria,2YTW2@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5948107_1	502025.Hoch_1523	2.191e-121	402.0	COG1232@1|root,COG1232@2|Bacteria,1RFQU@1224|Proteobacteria,43CYS@68525|delta/epsilon subdivisions,2X86X@28221|Deltaproteobacteria,2Z3MD@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_5948107_5	1254432.SCE1572_08850	1.28e-21	96.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2Z30G@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS3_k127_5974430_24	502025.Hoch_0573	3.728e-33	139.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX4C@1224|Proteobacteria,43BWW@68525|delta/epsilon subdivisions,2X77N@28221|Deltaproteobacteria,2YXG1@29|Myxococcales	2|Bacteria	DEZ	TIGRFAM cysteine-rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4215,RCC1_2
CMS3_k127_5974430_0	502025.Hoch_6414	1.073e-320	991.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2YU1P@29|Myxococcales	28221|Deltaproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
CMS3_k127_5974430_17	570952.ATVH01000013_gene2726	1.249e-67	240.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,2JTKV@204441|Rhodospirillales	204441|Rhodospirillales	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_5974430_11	518766.Rmar_2420	9.243e-107	354.0	COG1218@1|root,COG1218@2|Bacteria,4PEDQ@976|Bacteroidetes,1FIY0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS3_k127_5974430_27	1120950.KB892756_gene6670	3.102e-17	98.0	COG3055@1|root,COG3055@2|Bacteria,2HC50@201174|Actinobacteria	201174|Actinobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
CMS3_k127_5974430_15	400682.PAC_15722417	1.238e-83	308.0	COG1501@1|root,KOG1066@2759|Eukaryota,3AJ9M@33154|Opisthokonta	33154|Opisthokonta	G	Glycosyl hydrolases family 31	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_31
CMS3_k127_5974430_19	502025.Hoch_6683	5.893e-51	190.0	COG3921@1|root,COG3921@2|Bacteria	2|Bacteria	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
CMS3_k127_5974430_22	502025.Hoch_3631	2.486e-43	159.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,4399V@68525|delta/epsilon subdivisions,2X4HB@28221|Deltaproteobacteria,2YZ0N@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_5974430_31	215803.DB30_8877	4.513e-13	79.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,4399V@68525|delta/epsilon subdivisions,2X4HB@28221|Deltaproteobacteria,2YZ0N@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_5974430_12	502025.Hoch_5332	1.808e-105	350.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZAP@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_5974430_32	391625.PPSIR1_30060	7.868e-08	66.0	2BHU8@1|root,32BXY@2|Bacteria,1QZTM@1224|Proteobacteria,43CNI@68525|delta/epsilon subdivisions,2X7VV@28221|Deltaproteobacteria,2Z2V9@29|Myxococcales	391625.PPSIR1_30060|-	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5974430_13	595460.RRSWK_01373	2.832e-97	351.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
CMS3_k127_5974430_16	502025.Hoch_0400	9.68e-80	284.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Sigma54_activat
CMS3_k127_5974430_23	742767.HMPREF9456_01663	2.177e-41	177.0	COG0708@1|root,COG0708@2|Bacteria,4PKV5@976|Bacteroidetes,2G04P@200643|Bacteroidia,22ZHZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
CMS3_k127_5974430_4	266779.Meso_2458	1.982e-195	624.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
CMS3_k127_5974430_5	404589.Anae109_3668	1.153e-181	586.0	COG2197@1|root,COG2197@2|Bacteria,1R03J@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS3_k127_5974430_30	314270.RB2083_1555	4.392e-13	80.0	COG0558@1|root,COG0558@2|Bacteria,1NJC1@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_5974430_25	935548.KI912159_gene4523	1.145e-26	127.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2TV6V@28211|Alphaproteobacteria,43KTG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS3_k127_5974430_20	861299.J421_0060	1.975e-47	188.0	COG1524@1|root,COG1524@2|Bacteria,1ZT33@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_5974430_21	1117108.PAALTS15_24834	1.472e-44	171.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	HTH_3,Methyltransf_11,Methyltransf_23,Methyltransf_25,TehB
CMS3_k127_5974430_10	502025.Hoch_1456	1.081e-109	375.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z3I1@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5974430_1	378806.STAUR_1409	2.596e-242	794.0	COG0515@1|root,COG0515@2|Bacteria,1QX3Z@1224|Proteobacteria,430FI@68525|delta/epsilon subdivisions,2WVPS@28221|Deltaproteobacteria,2YTUJ@29|Myxococcales	28221|Deltaproteobacteria	T	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_5974430_18	215803.DB30_0229	5.741e-59	234.0	COG0457@1|root,COG0457@2|Bacteria,1QTNQ@1224|Proteobacteria,4380C@68525|delta/epsilon subdivisions,2X3AD@28221|Deltaproteobacteria,2YV4C@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_5974430_35	378806.STAUR_3314	0.0005325	51.0	2AJ12@1|root,319J6@2|Bacteria,1Q2X8@1224|Proteobacteria,438KD@68525|delta/epsilon subdivisions,2X3UY@28221|Deltaproteobacteria,2YX6J@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5974430_26	518766.Rmar_2816	9.69e-20	104.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447,ko:K17733	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011	-	-	-	Amidase_2,Big_2
CMS3_k127_5974430_33	765420.OSCT_1833	2.734e-06	60.0	COG3209@1|root,COG4733@1|root,COG3209@2|Bacteria,COG4733@2|Bacteria,2GBJ3@200795|Chloroflexi,377JF@32061|Chloroflexia	32061|Chloroflexia	MT	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14,Peptidase_C11,Peptidase_M23,fn3
CMS3_k127_5974430_3	614083.AWQR01000007_gene368	7.423e-197	627.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,4A9MZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_5974430_28	1121373.KB903643_gene3461	3.285e-15	89.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS3_k127_5974430_9	1142394.PSMK_25200	4.09e-134	441.0	COG0167@1|root,COG0167@2|Bacteria,2IX71@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.1,1.3.1.14	ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_5974430_7	1192034.CAP_8588	4.193e-166	548.0	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,42X2Z@68525|delta/epsilon subdivisions,2WTRX@28221|Deltaproteobacteria,2YTSH@29|Myxococcales	28221|Deltaproteobacteria	FH	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
CMS3_k127_5974430_8	760192.Halhy_3357	3.306e-150	508.0	COG0160@1|root,COG0160@2|Bacteria,4NIHH@976|Bacteroidetes,1IWIQ@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_5974430_2	1051632.TPY_1321	5.001e-202	640.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia	186801|Clostridia	F	PFAM amidohydrolase	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
CMS3_k127_5974430_6	1192034.CAP_8584	1.795e-170	550.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WP4Z@28221|Deltaproteobacteria,2YU7V@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS3_k127_5974430_14	448385.sce6401	7.827e-93	310.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YUP4@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_59813_7	502025.Hoch_3414	3.314e-76	277.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
CMS3_k127_59813_1	502025.Hoch_3415	1.691e-212	671.0	COG0031@1|root,COG0031@2|Bacteria,1QQKZ@1224|Proteobacteria,42PVJ@68525|delta/epsilon subdivisions,2WKKY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS3_k127_59813_5	502025.Hoch_3416	1.536e-109	363.0	COG0402@1|root,COG0402@2|Bacteria,1Q1P7@1224|Proteobacteria,42U3F@68525|delta/epsilon subdivisions,2WR49@28221|Deltaproteobacteria,2YVEP@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_59813_0	502025.Hoch_4147	0.0	1310.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS3_k127_59813_8	502025.Hoch_4717	5.205e-50	186.0	COG2821@1|root,COG2821@2|Bacteria,1NIC3@1224|Proteobacteria,433CJ@68525|delta/epsilon subdivisions,2WXQG@28221|Deltaproteobacteria,2Z1V4@29|Myxococcales	28221|Deltaproteobacteria	M	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
CMS3_k127_59813_4	1283299.AUKG01000002_gene4966	2.867e-120	401.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_59813_9	1297742.A176_05727	2.249e-42	165.0	2C7SF@1|root,3309N@2|Bacteria,1N9DW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_59813_6	502025.Hoch_4070	3.729e-107	369.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_59813_3	391625.PPSIR1_11465	4.43e-180	604.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_59813_2	502025.Hoch_5509	5.371e-185	620.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,43C0B@68525|delta/epsilon subdivisions,2X7B2@28221|Deltaproteobacteria,2Z3EU@29|Myxococcales	28221|Deltaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS3_k127_6017203_4	1048339.KB913029_gene1981	0.0009052	47.0	COG2931@1|root,COG2931@2|Bacteria,2I7DQ@201174|Actinobacteria,4EXHP@85013|Frankiales	2|Bacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS3_k127_6017203_1	485913.Krac_2435	4.077e-87	326.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_6017203_0	1382306.JNIM01000001_gene1023	2.244e-263	846.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_6017203_2	1382306.JNIM01000001_gene1022	4.015e-55	205.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_6017203_3	1122609.AUGT01000009_gene3207	8.457e-23	111.0	COG1404@1|root,COG1470@1|root,COG2373@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG2373@2|Bacteria,2HQ9W@201174|Actinobacteria,4DRST@85009|Propionibacteriales	201174|Actinobacteria	MO	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6017203_5	631362.Thi970DRAFT_01930	0.0009645	43.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales	135613|Chromatiales	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS3_k127_6018714_3	502025.Hoch_3174	2.327e-174	561.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,2Z3IH@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
CMS3_k127_6018714_4	502025.Hoch_3175	1.603e-161	514.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_6018714_7	502025.Hoch_3176	6.652e-103	361.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,42ZX4@68525|delta/epsilon subdivisions,2WVHE@28221|Deltaproteobacteria,2YUT3@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_6018714_1	502025.Hoch_3177	1.209e-222	725.0	COG2304@1|root,COG2304@2|Bacteria,1NX8F@1224|Proteobacteria,430QD@68525|delta/epsilon subdivisions,2WVNR@28221|Deltaproteobacteria,2YW4W@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_6018714_0	886293.Sinac_1156	2.756e-285	922.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_6018714_6	502025.Hoch_3178	2.068e-118	391.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WN0Z@28221|Deltaproteobacteria,2YUJN@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 3 N terminal domain	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS3_k127_6018714_9	483219.LILAB_10430	3.588e-22	112.0	COG1520@1|root,COG5184@1|root,COG1520@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YY0K@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
CMS3_k127_6018714_5	502025.Hoch_3181	1.482e-147	487.0	2AIV6@1|root,319CD@2|Bacteria,1Q2BD@1224|Proteobacteria,437XV@68525|delta/epsilon subdivisions,2X37S@28221|Deltaproteobacteria,2YUR7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6018714_2	502025.Hoch_3182	5.463e-184	585.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,2YX7S@29|Myxococcales	28221|Deltaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
CMS3_k127_6030655_0	502025.Hoch_0154	7.462e-47	181.0	29XG3@1|root,30J6J@2|Bacteria,1QSSU@1224|Proteobacteria,4355H@68525|delta/epsilon subdivisions,2X95V@28221|Deltaproteobacteria,2Z23G@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6055179_2	1278073.MYSTI_02453	1.311e-31	129.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42Q78@68525|delta/epsilon subdivisions,2WJHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarboxypepD_reg,DUF3520,VWA,vWF_A
CMS3_k127_6055179_1	1297742.A176_01014	7.957e-68	236.0	COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,42ZYJ@68525|delta/epsilon subdivisions,2WRXQ@28221|Deltaproteobacteria,2YUY5@29|Myxococcales	28221|Deltaproteobacteria	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
CMS3_k127_6055179_3	67275.JOAP01000004_gene6658	1.525e-05	53.0	COG1396@1|root,COG1396@2|Bacteria,2GNTQ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS3_k127_6055179_0	926566.Terro_2393	1.113e-138	452.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6067757_2	309807.SRU_1149	2.004e-93	325.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1FIM8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_6067757_0	391625.PPSIR1_08147	5.447e-135	449.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2YY2P@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
CMS3_k127_6067757_1	502025.Hoch_6002	1.864e-97	325.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YURD@29|Myxococcales	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_6067757_4	929712.KI912613_gene306	7.329e-05	54.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
CMS3_k127_6067757_3	543632.JOJL01000002_gene8254	4.984e-05	56.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4D8Q0@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE,TPR_12
CMS3_k127_6073316_2	502025.Hoch_6622	7.39e-62	227.0	COG4214@1|root,COG4214@2|Bacteria,1QYSC@1224|Proteobacteria	1224|Proteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10544	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	BPD_transp_2
CMS3_k127_6073316_0	1254432.SCE1572_33190	1.645e-126	447.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,42YKP@68525|delta/epsilon subdivisions,2WUQ9@28221|Deltaproteobacteria,2YU8Z@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	rbsA	-	3.6.3.17	ko:K02056,ko:K05776,ko:K10441,ko:K10542,ko:K10545,ko:K10548	ko02010,map02010	M00189,M00212,M00214,M00215,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
CMS3_k127_6073316_1	1297742.A176_06439	1.711e-86	312.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_15
CMS3_k127_607378_1	383381.EH30_10380	2.412e-59	206.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria,2K28H@204457|Sphingomonadales	204457|Sphingomonadales	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_607378_0	1206731.BAGB01000147_gene4240	4.339e-150	497.0	COG1053@1|root,COG1053@2|Bacteria,2IA7Q@201174|Actinobacteria,4G5SH@85025|Nocardiaceae	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
CMS3_k127_6077369_1	1492922.GY26_06660	2.406e-43	171.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1J5AK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG0657 Esterase lipase	aes	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CMS3_k127_6077369_0	1254432.SCE1572_27875	3.51e-301	964.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36
CMS3_k127_6077369_2	640511.BC1002_6656	4.136e-26	120.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VSSJ@28216|Betaproteobacteria,1K5FA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,SAM_1,TPR_12,Trans_reg_C
CMS3_k127_6083918_4	502025.Hoch_4176	1.493e-59	214.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42Q7U@68525|delta/epsilon subdivisions,2WPC0@28221|Deltaproteobacteria,2YY7Y@29|Myxococcales	28221|Deltaproteobacteria	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS3_k127_6083918_0	502025.Hoch_4175	2.379e-142	459.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YWJD@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK-1	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_6083918_3	502025.Hoch_4174	4.841e-65	225.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2X5QF@28221|Deltaproteobacteria,2Z36V@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_6083918_7	439235.Dalk_1095	6.816e-18	88.0	292SY@1|root,2ZQAN@2|Bacteria,1P40A@1224|Proteobacteria,433JE@68525|delta/epsilon subdivisions,2WYAR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6083918_5	502025.Hoch_4172	5.144e-38	149.0	COG1716@1|root,COG1716@2|Bacteria,1Q2JX@1224|Proteobacteria,433U4@68525|delta/epsilon subdivisions,2X3GN@28221|Deltaproteobacteria,2YW0G@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_6083918_2	502025.Hoch_4171	4.016e-89	296.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2WNG7@28221|Deltaproteobacteria,2YUWK@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS3_k127_6083918_1	502025.Hoch_4170	2.175e-114	379.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,2YUT5@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class II (D, K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
CMS3_k127_6083918_8	391625.PPSIR1_25111	6.164e-06	56.0	COG5549@1|root,COG5549@2|Bacteria,1PEIF@1224|Proteobacteria,43931@68525|delta/epsilon subdivisions,2X48W@28221|Deltaproteobacteria,2YYIC@29|Myxococcales	28221|Deltaproteobacteria	O	Dual-action HEIGH metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M57
CMS3_k127_6083918_6	1144275.COCOR_05799	2.279e-26	122.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria	1224|Proteobacteria	E	COG2303 Choline dehydrogenase and related flavoproteins	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_608821_4	1192034.CAP_3433	2.679e-63	229.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,437Y9@68525|delta/epsilon subdivisions,2X9RZ@28221|Deltaproteobacteria,2YUSF@29|Myxococcales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS3_k127_608821_7	448385.sce4424	2.804e-50	194.0	2A45R@1|root,30SQS@2|Bacteria,1PC2Q@1224|Proteobacteria,4387Q@68525|delta/epsilon subdivisions,2X3HH@28221|Deltaproteobacteria,2YW4R@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS3_k127_608821_2	502025.Hoch_4790	1.407e-91	317.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YYCB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_608821_0	335543.Sfum_0829	5.371e-119	391.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2MREJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_608821_10	502025.Hoch_6608	2.907e-27	119.0	COG1468@1|root,COG1468@2|Bacteria,1QAI2@1224|Proteobacteria,43E1D@68525|delta/epsilon subdivisions,2X952@28221|Deltaproteobacteria,2Z1ZI@29|Myxococcales	28221|Deltaproteobacteria	L	defense response to virus	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_608821_5	639030.JHVA01000001_gene2022	1.253e-58	214.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_608821_8	715451.ambt_10865	1.458e-45	175.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria,464F0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
CMS3_k127_608821_1	1229780.BN381_130241	1.971e-97	327.0	COG2220@1|root,COG2220@2|Bacteria,2GMFQ@201174|Actinobacteria	201174|Actinobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS3_k127_608821_3	448385.sce3602	1.616e-88	330.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.3.5,3.2.1.14	ko:K01081,ko:K01183,ko:K20276	ko00230,ko00240,ko00520,ko00760,ko01100,ko01110,ko02024,map00230,map00240,map00520,map00760,map01100,map01110,map02024	-	R00183,R00511,R00963,R01126,R01206,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02334,R02719,R03346	RC00017,RC00467	ko00000,ko00001,ko01000	-	GH18	-	F5_F8_type_C,Melibiase_2,NPCBM_assoc,PKD,PPC,Trypsin_2,VPEP
CMS3_k127_608821_9	1121930.AQXG01000001_gene1405	1.328e-35	140.0	COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,1ITWU@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K01802,ko:K03774,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS3_k127_608821_6	1210884.HG799468_gene13789	1.477e-51	205.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_608821_12	1144275.COCOR_03942	9.26e-07	55.0	COG0488@1|root,COG0488@2|Bacteria,1QUVR@1224|Proteobacteria,42P66@68525|delta/epsilon subdivisions,2WJ2D@28221|Deltaproteobacteria,2YWET@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_608821_11	716544.wcw_1110	8.315e-17	80.0	COG2947@1|root,COG2947@2|Bacteria,2JH2Z@204428|Chlamydiae	204428|Chlamydiae	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS3_k127_6110453_2	502025.Hoch_5811	1.378e-38	147.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6110453_0	1278073.MYSTI_03787	1.175e-168	547.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42Q78@68525|delta/epsilon subdivisions,2WJHK@28221|Deltaproteobacteria,2YU6Z@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
CMS3_k127_6110453_1	502025.Hoch_4638	3.521e-40	156.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_6117687_5	502025.Hoch_6795	1.26e-67	255.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_6117687_9	215803.DB30_3516	3.225e-19	103.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,438GN@68525|delta/epsilon subdivisions,2X3RG@28221|Deltaproteobacteria,2YWXM@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_6117687_10	1337093.MBE-LCI_3444	1.68e-16	96.0	COG1361@1|root,COG1361@2|Bacteria,1R59C@1224|Proteobacteria,2TUS0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_6117687_11	215803.DB30_5455	5.965e-15	91.0	COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
CMS3_k127_6117687_12	472175.EL18_00003	0.0002444	56.0	COG2304@1|root,COG2304@2|Bacteria,1PBVT@1224|Proteobacteria,2U3NK@28211|Alphaproteobacteria,43HG7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
CMS3_k127_6117687_3	502025.Hoch_6795	3.301e-85	323.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_6117687_8	330214.NIDE1608	2.141e-21	103.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
CMS3_k127_6117687_6	1095769.CAHF01000011_gene2048	1.031e-28	124.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,4735G@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6117687_1	502025.Hoch_2386	2.07e-105	369.0	COG0515@1|root,COG3063@1|root,COG0515@2|Bacteria,COG3063@2|Bacteria,1Q2R6@1224|Proteobacteria,433VB@68525|delta/epsilon subdivisions,2X3MY@28221|Deltaproteobacteria,2YWK6@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6117687_2	502025.Hoch_5885	3.674e-102	338.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,439RM@68525|delta/epsilon subdivisions,2X54F@28221|Deltaproteobacteria,2Z03P@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_6117687_0	502025.Hoch_4868	9.295e-159	542.0	COG2909@1|root,COG3710@1|root,COG2909@2|Bacteria,COG3710@2|Bacteria,1QAQG@1224|Proteobacteria,43E31@68525|delta/epsilon subdivisions,2WZJI@28221|Deltaproteobacteria,2Z29P@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS3_k127_6117687_4	404589.Anae109_2216	8.007e-74	252.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2WISR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_6120997_10	945713.IALB_1235	2.251e-05	52.0	28J1N@1|root,2Z8YI@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS3_k127_6120997_4	1245471.PCA10_07370	6.8e-43	177.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1YDRA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS3_k127_6120997_0	502025.Hoch_5509	1.038e-190	634.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,43C0B@68525|delta/epsilon subdivisions,2X7B2@28221|Deltaproteobacteria,2Z3EU@29|Myxococcales	28221|Deltaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
CMS3_k127_6120997_3	1288826.MSNKSG1_14177	7.958e-102	340.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,1RRTZ@1236|Gammaproteobacteria,464S0@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	CorA-like Mg2+ transporter protein	zntB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
CMS3_k127_6120997_8	768671.ThimaDRAFT_1754	9.034e-08	57.0	2DQWF@1|root,3392H@2|Bacteria,1N93V@1224|Proteobacteria,1SFNS@1236|Gammaproteobacteria,1WZ6Y@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
CMS3_k127_6120997_2	1254432.SCE1572_37735	1.446e-112	394.0	COG2010@1|root,COG2010@2|Bacteria,1QX4J@1224|Proteobacteria,43CNY@68525|delta/epsilon subdivisions,2X7W8@28221|Deltaproteobacteria,2YX21@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,Cu2_monooxygen
CMS3_k127_6120997_7	1123508.JH636439_gene345	2.595e-09	71.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_6120997_5	1123276.KB893245_gene1111	1.131e-23	116.0	COG2010@1|root,COG2010@2|Bacteria,4PPRH@976|Bacteroidetes,47YQV@768503|Cytophagia	976|Bacteroidetes	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_6120997_6	483219.LILAB_13220	4.649e-23	103.0	2AGJK@1|root,316SP@2|Bacteria,1PXYX@1224|Proteobacteria,434YM@68525|delta/epsilon subdivisions,2WZ9F@28221|Deltaproteobacteria,2Z1MY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6120997_1	502025.Hoch_4223	1.113e-117	402.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,439A0@68525|delta/epsilon subdivisions,2X4HG@28221|Deltaproteobacteria,2YZ10@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_6137582_0	502025.Hoch_3597	3.022e-210	676.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CBM9_1,CarboxypepD_reg,DUF11,DUF4384,NPCBM_assoc,PA14,PEGA
CMS3_k127_6137582_4	743525.TSC_c23990	1.583e-14	84.0	COG5624@1|root,COG5624@2|Bacteria,1WJK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6137582_1	502025.Hoch_3596	3.934e-91	306.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2YVGU@29|Myxococcales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS3_k127_6137582_2	1121346.KB899811_gene1687	6.93e-64	228.0	COG1028@1|root,COG1028@2|Bacteria,1UI3U@1239|Firmicutes,4ISCX@91061|Bacilli,26UQ4@186822|Paenibacillaceae	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	yusZ	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_6145561_7	502025.Hoch_2208	1.893e-85	290.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,2YU5T@29|Myxococcales	28221|Deltaproteobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS3_k127_6145561_0	502025.Hoch_5559	2.541e-281	887.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2YU4V@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
CMS3_k127_6145561_1	1254432.SCE1572_15335	2.884e-173	556.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4Y@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6145561_4	502025.Hoch_2511	5.796e-127	424.0	2AIWW@1|root,319EI@2|Bacteria,1Q2HU@1224|Proteobacteria,4384N@68525|delta/epsilon subdivisions,2X3EQ@28221|Deltaproteobacteria,2YVQU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6145561_5	502025.Hoch_2514	8.777e-106	349.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2YV9J@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS3_k127_6145561_3	502025.Hoch_2515	6.905e-139	454.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YU1B@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_6145561_9	1430331.EP10_10570	3.742e-15	86.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4HIRG@91061|Bacilli,1WFX4@129337|Geobacillus	91061|Bacilli	H	Sirohaem biosynthesis protein central	sirC	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
CMS3_k127_6145561_11	929558.SMGD1_0994	1.78e-14	84.0	COG3794@1|root,COG3794@2|Bacteria,1Q9I8@1224|Proteobacteria,42XQQ@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
CMS3_k127_6145561_10	944480.ATUV01000002_gene132	3.941e-15	89.0	COG0558@1|root,COG1213@1|root,COG0558@2|Bacteria,COG1213@2|Bacteria,1NN43@1224|Proteobacteria,432HN@68525|delta/epsilon subdivisions,2WYCV@28221|Deltaproteobacteria,2M7MC@213113|Desulfurellales	28221|Deltaproteobacteria	IM	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS3_k127_6145561_2	502025.Hoch_5878	4.508e-159	526.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42MDS@68525|delta/epsilon subdivisions,2WJM3@28221|Deltaproteobacteria,2YTXA@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
CMS3_k127_6145561_6	502025.Hoch_5876	6.017e-98	333.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,2Z21W@29|Myxococcales	28221|Deltaproteobacteria	L	Putative RNA methylase family UPF0020	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
CMS3_k127_6145561_12	1461577.CCMH01000037_gene115	7.867e-14	78.0	2CK2Y@1|root,32SBF@2|Bacteria,4NTZD@976|Bacteroidetes,1I4T5@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM Photosynthetic reaction centre cytochrome C subunit	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	CytoC_RC
CMS3_k127_6145561_8	596152.DesU5LDRAFT_1275	1.741e-19	92.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42PHH@68525|delta/epsilon subdivisions,2WV9C@28221|Deltaproteobacteria,2M8TF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS3_k127_6145561_13	1297742.A176_05190	1.851e-06	55.0	2BQGY@1|root,32JCG@2|Bacteria,1Q9S5@1224|Proteobacteria,434JV@68525|delta/epsilon subdivisions,2WYX4@28221|Deltaproteobacteria,2Z0UF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6186451_0	1192034.CAP_5604	7.662e-131	434.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
CMS3_k127_6206488_1	1125863.JAFN01000001_gene2171	1.286e-126	417.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_6206488_3	391625.PPSIR1_28093	1.517e-91	329.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS3_k127_6206488_14	1161401.ASJA01000002_gene2755	0.0007773	51.0	COG2931@1|root,COG3420@1|root,COG2931@2|Bacteria,COG3420@2|Bacteria,1NRRU@1224|Proteobacteria,2UQ51@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6206488_12	316067.Geob_2464	1.161e-05	58.0	COG4447@1|root,COG4447@2|Bacteria,1PK4G@1224|Proteobacteria,431VP@68525|delta/epsilon subdivisions,2WW8N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
CMS3_k127_6206488_0	502025.Hoch_6020	0.0	1573.0	COG0457@1|root,COG0515@1|root,COG0642@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
CMS3_k127_6206488_4	511051.CSE_12980	1.41e-53	215.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
CMS3_k127_6206488_2	290397.Adeh_3471	1.502e-112	382.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6206488_10	1278073.MYSTI_06251	1.334e-16	95.0	COG0457@1|root,COG0457@2|Bacteria,1NK0T@1224|Proteobacteria,42X28@68525|delta/epsilon subdivisions,2WT4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6206488_6	1191523.MROS_0394	7.293e-47	194.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_0394|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6206488_13	1218108.KB908296_gene3032	4.687e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes,1I1JW@117743|Flavobacteriia	976|Bacteroidetes	H	tetratricopeptide repeat	batC	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_6206488_8	378806.STAUR_6340	6.419e-35	154.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2YV46@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
CMS3_k127_6206488_5	448385.sce6504	1.125e-47	187.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2WKKE@28221|Deltaproteobacteria,2YXC9@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CMS3_k127_6206488_9	391625.PPSIR1_31753	1.175e-16	92.0	2DQMB@1|root,337KD@2|Bacteria,1NKJH@1224|Proteobacteria,42X0X@68525|delta/epsilon subdivisions,2WSJT@28221|Deltaproteobacteria,2YVNT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6206488_7	1499967.BAYZ01000069_gene1845	2.215e-36	142.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_6227057_4	886293.Sinac_1156	6.332e-130	442.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_6227057_13	290397.Adeh_1153	1.708e-50	188.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42QU8@68525|delta/epsilon subdivisions,2X5Q5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS3_k127_6227057_8	1254432.SCE1572_32545	5.486e-80	283.0	COG1266@1|root,COG1266@2|Bacteria,1R5BW@1224|Proteobacteria	1224|Proteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_6227057_0	502025.Hoch_6480	0.0	1034.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_6227057_19	1254432.SCE1572_04970	1.665e-18	91.0	2AH1Z@1|root,317B3@2|Bacteria,1PYKX@1224|Proteobacteria,435FG@68525|delta/epsilon subdivisions,2WZT0@28221|Deltaproteobacteria,2Z2PH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6227057_20	990285.RGCCGE502_18060	4.319e-13	74.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4B88G@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
CMS3_k127_6227057_3	1120972.AUMH01000005_gene834	4.969e-133	443.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HEG0@91061|Bacilli,27ANS@186823|Alicyclobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6227057_10	391625.PPSIR1_13885	1.338e-68	247.0	COG1409@1|root,COG1409@2|Bacteria,1NXRI@1224|Proteobacteria,43547@68525|delta/epsilon subdivisions,2WZF9@28221|Deltaproteobacteria,2Z20E@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS3_k127_6227057_11	1206743.BAGM01000101_gene2583	9.302e-58	210.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,4G0CF@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_6227057_12	909663.KI867150_gene87	1.039e-51	199.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
CMS3_k127_6227057_1	502025.Hoch_5825	3.269e-168	547.0	COG1454@1|root,COG3508@1|root,COG1454@2|Bacteria,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,42Z7C@68525|delta/epsilon subdivisions,2WTZE@28221|Deltaproteobacteria,2YY2N@29|Myxococcales	28221|Deltaproteobacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CMS3_k127_6227057_9	1054213.HMPREF9946_04103	4.727e-69	249.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	maleylacetate reductase	macA	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS3_k127_6227057_16	391625.PPSIR1_30474	4.388e-26	125.0	COG0745@1|root,COG0745@2|Bacteria	391625.PPSIR1_30474|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6227057_6	211165.AJLN01000116_gene3228	4.445e-108	364.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1JJDA@1189|Stigonemataceae	1117|Cyanobacteria	O	Peptide methionine sulfoxide reductase	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS3_k127_6227057_22	502025.Hoch_5781	2.928e-09	69.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03110,ko:K03832	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	2.C.1.1,3.A.5.1,3.A.5.2,3.A.5.7	-	-	CarbopepD_reg_2,TonB_2,TonB_C
CMS3_k127_6227057_5	502025.Hoch_5887	1.501e-128	462.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_6227057_17	745411.B3C1_17847	3.284e-24	121.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T1I4@1236|Gammaproteobacteria,1J6CG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2203 FOG GAF domain	cyaA	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
CMS3_k127_6227057_15	448385.sce2313	1.585e-39	171.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,439AS@68525|delta/epsilon subdivisions,2X4IF@28221|Deltaproteobacteria,2YZ31@29|Myxococcales	28221|Deltaproteobacteria	KLT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Response_reg
CMS3_k127_6227057_14	671143.DAMO_1570	1.807e-48	188.0	COG0639@1|root,COG0639@2|Bacteria,2NQ2C@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase	prp1	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
CMS3_k127_6227057_21	215803.DB30_7922	7.645e-13	75.0	2EV1C@1|root,33NGG@2|Bacteria,1NKKY@1224|Proteobacteria,42X6Y@68525|delta/epsilon subdivisions,2WTH7@28221|Deltaproteobacteria,2Z0VE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6227057_2	861299.J421_3743	1.019e-147	485.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_6227057_7	502025.Hoch_0262	6.972e-83	299.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_6227057_24	1297742.A176_05991	0.0002252	51.0	2APHR@1|root,31EKS@2|Bacteria,1QBX0@1224|Proteobacteria,435IF@68525|delta/epsilon subdivisions,2WZW3@28221|Deltaproteobacteria,2Z2VA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6227057_23	391625.PPSIR1_40859	1.064e-06	52.0	2DSD6@1|root,33FM0@2|Bacteria,1PBXM@1224|Proteobacteria,43862@68525|delta/epsilon subdivisions,2X3FW@28221|Deltaproteobacteria,2YVX7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6234848_1	502025.Hoch_3765	4.746e-123	398.0	COG0247@1|root,COG1150@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2YUAI@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8
CMS3_k127_6234848_12	1220534.B655_0330	5.862e-06	59.0	COG5635@1|root,arCOG06468@1|root,arCOG02967@2157|Archaea,arCOG06468@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
CMS3_k127_6234848_0	1192034.CAP_7183	1.492e-182	591.0	COG2303@1|root,COG2303@2|Bacteria,1PEB3@1224|Proteobacteria,42WR0@68525|delta/epsilon subdivisions,2WS23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_6234848_8	7739.XP_002602709.1	1.793e-14	82.0	COG0790@1|root,KOG4014@2759|Eukaryota,38B5E@33154|Opisthokonta,3BA0U@33208|Metazoa,3CV6K@33213|Bilateria,480DC@7711|Chordata	33208|Metazoa	S	Cytochrome c oxidase assembly factor 7	COA7	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K18180	ko04714,map04714	-	-	-	ko00000,ko00001,ko03029	-	-	-	Sel1
CMS3_k127_6234848_10	1144275.COCOR_06061	6.538e-10	72.0	COG3712@1|root,COG3712@2|Bacteria,1PBZ9@1224|Proteobacteria,433U5@68525|delta/epsilon subdivisions,2X3GP@28221|Deltaproteobacteria,2YW0J@29|Myxococcales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,zf-HC2
CMS3_k127_6234848_5	1254432.SCE1572_34880	3.497e-31	130.0	COG1595@1|root,COG1595@2|Bacteria,1R7KF@1224|Proteobacteria,4385W@68525|delta/epsilon subdivisions,2X9YP@28221|Deltaproteobacteria,2YVWM@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6234848_2	502025.Hoch_2327	2.156e-60	223.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	bcsC	-	1.8.1.9,2.7.11.1	ko:K00384,ko:K02453,ko:K11912,ko:K14949,ko:K20543	ko00450,ko02025,ko03070,ko05111,ko05152,map00450,map02025,map03070,map05111,map05152	M00331	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02044	1.B.55.3,3.A.15	-	-	BCSC_C,Pkinase,PknG_TPR,PknG_rubred,TPR_16,TPR_19,TPR_8
CMS3_k127_6234848_6	406124.ACPC01000019_gene3051	1.026e-27	120.0	COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,4HKIJ@91061|Bacilli,1ZHSP@1386|Bacillus	91061|Bacilli	S	COG3030 Protein affecting phage T7 exclusion by the F plasmid	fxsA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
CMS3_k127_6234848_11	525909.Afer_0938	5.681e-07	59.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4CN9D@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS3_k127_6234848_3	1177181.T9A_02173	9.372e-55	205.0	COG1073@1|root,COG1073@2|Bacteria,1PQAX@1224|Proteobacteria,1S02C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF2048
CMS3_k127_6234848_7	502025.Hoch_4784	9.71e-25	108.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,2YYG9@29|Myxococcales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
CMS3_k127_6246306_1	502025.Hoch_0142	4.954e-156	497.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2YV60@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS3_k127_6246306_0	502025.Hoch_6834	4.271e-198	633.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2YV6I@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS3_k127_6246306_3	502025.Hoch_6819	3.548e-77	273.0	29RQC@1|root,30CTT@2|Bacteria,1QTPW@1224|Proteobacteria,435D4@68525|delta/epsilon subdivisions,2WZQP@28221|Deltaproteobacteria,2Z2IY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_6246306_2	502025.Hoch_6820	6.117e-136	449.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2YUZA@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
CMS3_k127_6246306_4	1382306.JNIM01000001_gene1070	2.855e-62	231.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_6246306_5	502025.Hoch_6446	5.31e-38	147.0	COG0745@1|root,COG3215@1|root,COG0745@2|Bacteria,COG3215@2|Bacteria,1QXTP@1224|Proteobacteria,43C61@68525|delta/epsilon subdivisions,2X7G9@28221|Deltaproteobacteria,2YVX0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
CMS3_k127_6260780_4	502025.Hoch_2317	6.009e-79	284.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS3_k127_6260780_7	1122939.ATUD01000001_gene643	3.462e-46	190.0	COG3268@1|root,COG3268@2|Bacteria,2GMKU@201174|Actinobacteria,4CSJP@84995|Rubrobacteria	84995|Rubrobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
CMS3_k127_6260780_0	502025.Hoch_2315	3.869e-154	514.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,2YU0X@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_6260780_6	1192034.CAP_6129	1.405e-55	222.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WR3G@28221|Deltaproteobacteria,2YXS5@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_6260780_8	1521187.JPIM01000061_gene1000	3.371e-37	149.0	COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi,375Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_6260780_2	502025.Hoch_1786	6.421e-133	433.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,2YTWJ@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_6260780_1	502025.Hoch_2736	1.103e-145	491.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_2736|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6283999_7	502025.Hoch_4508	4.978e-48	186.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2Z0RQ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6283999_2	448385.sce3387	3.073e-127	428.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6283999_3	502025.Hoch_6095	2.694e-120	398.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YUV2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS3_k127_6283999_0	502025.Hoch_6093	1.303e-153	512.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS3_k127_6283999_4	502025.Hoch_6092	5.48e-96	340.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2WJW1@28221|Deltaproteobacteria,2YUUB@29|Myxococcales	28221|Deltaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_6283999_9	502025.Hoch_6091	1.818e-35	140.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,42UZH@68525|delta/epsilon subdivisions,2WR2R@28221|Deltaproteobacteria,2YVFS@29|Myxococcales	28221|Deltaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CMS3_k127_6283999_1	1242864.D187_006516	2.424e-139	467.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_6283999_5	493475.GARC_3232	3.305e-89	301.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,46D3A@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
CMS3_k127_6283999_6	502025.Hoch_1948	7.967e-57	214.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
CMS3_k127_6283999_8	1254432.SCE1572_43940	1.975e-47	177.0	28T75@1|root,2ZFFV@2|Bacteria,1RBYB@1224|Proteobacteria,43DNG@68525|delta/epsilon subdivisions,2X6JU@28221|Deltaproteobacteria,2Z10T@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6298595_7	1149133.ppKF707_2621	6.086e-32	141.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1YJDT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6298595_4	1278073.MYSTI_04822	2.94e-104	349.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6298595_1	1278073.MYSTI_04821	8.191e-169	537.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,42S7Z@68525|delta/epsilon subdivisions,2WNZM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2199	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6298595_0	66377.JOBH01000002_gene503	4.513e-181	593.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	ltp3	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
CMS3_k127_6298595_3	1278073.MYSTI_04818	5.639e-154	502.0	COG0183@1|root,COG0183@2|Bacteria,1PSXC@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
CMS3_k127_6298595_5	935866.JAER01000002_gene1929	6.281e-53	198.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,4DMZC@85009|Propionibacteriales	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_6298595_6	1278073.MYSTI_04816	7.005e-53	199.0	COG1545@1|root,COG1545@2|Bacteria,1PTPN@1224|Proteobacteria,432C1@68525|delta/epsilon subdivisions,2WXU2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	OB_aCoA_assoc
CMS3_k127_6298595_8	1254432.SCE1572_31405	8.659e-11	74.0	COG1141@1|root,COG1141@2|Bacteria,1QAPI@1224|Proteobacteria,4357M@68525|delta/epsilon subdivisions,2X96K@28221|Deltaproteobacteria,2Z28A@29|Myxococcales	28221|Deltaproteobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
CMS3_k127_6298595_2	1206725.BAFU01000218_gene4281	7.808e-159	511.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4FWXS@85025|Nocardiaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
CMS3_k127_6309368_0	502025.Hoch_5407	1.898e-192	612.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_6340937_0	159749.K0STR7	1.043e-40	158.0	COG0800@1|root,2QVAJ@2759|Eukaryota,2XC3K@2836|Bacillariophyta	2836|Bacillariophyta	G	KDPG and KHG aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase
CMS3_k127_6340937_1	1121918.ARWE01000001_gene223	1.35e-24	121.0	COG3419@1|root,COG3419@2|Bacteria	2|Bacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
CMS3_k127_6340937_5	395493.BegalDRAFT_3063	5.575e-05	51.0	COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,1SC9Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
CMS3_k127_6340937_4	1415780.JPOG01000001_gene3102	1.17e-07	64.0	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1S7JH@1236|Gammaproteobacteria,1X6RM@135614|Xanthomonadales	135614|Xanthomonadales	NU	pilus assembly protein PilW	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
CMS3_k127_6340937_2	502025.Hoch_6795	1.809e-09	63.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_6353194_6	502025.Hoch_1890	1.188e-17	83.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS3_k127_6353194_0	502025.Hoch_1891	2.86e-130	425.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria,2YYV1@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS3_k127_6353194_1	502025.Hoch_0232	1.306e-113	383.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YUIT@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_6353194_4	1232410.KI421413_gene692	1.024e-95	326.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS3_k127_6353194_2	502025.Hoch_5651	3.004e-99	329.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YUT4@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_6353194_5	502025.Hoch_5650	6.83e-21	104.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2YVWU@29|Myxococcales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_6353194_3	502025.Hoch_5649	5.17e-97	324.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2YXTZ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_6366350_3	1192034.CAP_8905	5.626e-08	54.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2YTTC@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_6366350_0	502025.Hoch_3755	2.914e-92	323.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2YUTG@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
CMS3_k127_6366350_1	502025.Hoch_3756	8.066e-64	220.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,2YU1S@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_6386950_3	448385.sce3620	3.462e-47	173.0	COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,439ZZ@68525|delta/epsilon subdivisions,2X4EZ@28221|Deltaproteobacteria,2YYW8@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.77,1.2.1.91,3.3.2.12	ko:K02618,ko:K15514	ko00360,ko00362,ko01120,map00360,map00362,map01120	-	R09554,R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_6386950_1	1254432.SCE1572_34165	1.399e-118	404.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_34165|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_6386950_0	945713.IALB_2872	5.517e-175	561.0	COG1048@1|root,COG1048@2|Bacteria	2|Bacteria	C	aconitate hydratase activity	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_6421596_1	1487953.JMKF01000043_gene2565	1.324e-09	70.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,1G8GY@1117|Cyanobacteria,1HCH7@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6425927_1	585531.HMPREF0063_12492	2.487e-82	280.0	COG1064@1|root,COG1064@2|Bacteria,2IP10@201174|Actinobacteria,4DWMY@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_6425927_2	1396141.BATP01000005_gene5986	4.138e-35	152.0	COG2267@1|root,COG2267@2|Bacteria,46XEA@74201|Verrucomicrobia,2IVN7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_6425927_4	1123399.AQVE01000003_gene2089	3.396e-11	69.0	COG3255@1|root,COG3255@2|Bacteria,1N206@1224|Proteobacteria,1S8RI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_6425927_0	1278073.MYSTI_04823	5.046e-129	428.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,42NUM@68525|delta/epsilon subdivisions,2WKR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 2-nitropropane dioxygenase NPD	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_6425927_3	1206726.BAFV01000123_gene6333	1.725e-22	102.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4FWXS@85025|Nocardiaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
CMS3_k127_6431577_1	502025.Hoch_3644	3.254e-151	487.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,2YUC0@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS3_k127_6431577_4	56780.SYN_01352	7.983e-35	136.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS3_k127_6431577_3	502025.Hoch_2238	5.303e-37	142.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2YVHC@29|Myxococcales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS3_k127_6431577_2	502025.Hoch_6765	4.972e-135	438.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,2YUP1@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
CMS3_k127_6431577_0	1260251.SPISAL_07110	2.889e-157	511.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS3_k127_6431577_5	246197.MXAN_1463	4.398e-27	111.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YTXJ@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_6451558_28	404589.Anae109_4341	2.202e-16	87.0	COG0457@1|root,COG0457@2|Bacteria,1QQ0R@1224|Proteobacteria,433U8@68525|delta/epsilon subdivisions,2X3GZ@28221|Deltaproteobacteria,2YW20@29|Myxococcales	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,zinc_ribbon_4
CMS3_k127_6451558_1	391625.PPSIR1_34317	9.913e-158	522.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,4347K@68525|delta/epsilon subdivisions,2X42E@28221|Deltaproteobacteria,2YY2K@29|Myxococcales	28221|Deltaproteobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_6451558_27	1541065.JRFE01000009_gene4500	1.871e-23	113.0	COG2931@1|root,COG2931@2|Bacteria,1GCGV@1117|Cyanobacteria,3VKJD@52604|Pleurocapsales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS3_k127_6451558_16	502025.Hoch_2672	4.713e-61	218.0	COG0546@1|root,COG0546@2|Bacteria,1P7U4@1224|Proteobacteria,432VF@68525|delta/epsilon subdivisions,2WYF8@28221|Deltaproteobacteria,2YVV8@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	gph1	-	-	-	-	-	-	-	-	-	-	-	HAD,Hydrolase_like
CMS3_k127_6451558_17	671143.DAMO_1672	1.897e-59	211.0	COG0723@1|root,COG0723@2|Bacteria,2NRUZ@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS3_k127_6451558_3	671143.DAMO_1671	7.773e-136	435.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS3_k127_6451558_7	671143.DAMO_1670	5.071e-104	344.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
CMS3_k127_6451558_22	2340.JV46_19520	2.155e-42	165.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,1SFWW@1236|Gammaproteobacteria,1JBGH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
CMS3_k127_6451558_12	1120956.JHZK01000027_gene1193	4.127e-82	283.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2UAN7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_6451558_29	292459.STH1011	1.197e-08	68.0	COG0170@1|root,COG1836@1|root,COG0170@2|Bacteria,COG1836@2|Bacteria,1V7I1@1239|Firmicutes,24GQ3@186801|Clostridia	186801|Clostridia	I	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
CMS3_k127_6451558_13	1123258.AQXZ01000018_gene668	7.359e-76	274.0	COG1233@1|root,COG1233@2|Bacteria	2|Bacteria	Q	all-trans-retinol 13,14-reductase activity	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_6451558_25	290397.Adeh_0929	3.409e-33	140.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria,2YUZS@29|Myxococcales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CMS3_k127_6451558_19	290397.Adeh_0928	3.648e-53	211.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
CMS3_k127_6451558_14	502025.Hoch_0566	2.053e-73	254.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z13M@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CMS3_k127_6451558_11	502025.Hoch_0567	1.338e-91	306.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,42NEX@68525|delta/epsilon subdivisions,2WJ1Y@28221|Deltaproteobacteria,2YUXF@29|Myxococcales	28221|Deltaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS3_k127_6451558_15	502025.Hoch_0568	7.973e-67	252.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2YVIB@29|Myxococcales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
CMS3_k127_6451558_4	502025.Hoch_1806	9.416e-131	442.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_6451558_21	502025.Hoch_1807	5.509e-48	179.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,2YW1G@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_6451558_20	502025.Hoch_1808	1.122e-51	187.0	COG0848@1|root,COG0848@2|Bacteria,1QAS7@1224|Proteobacteria,43E3G@68525|delta/epsilon subdivisions,2WZKU@28221|Deltaproteobacteria,2Z2C1@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_6451558_9	502025.Hoch_1809	1.9e-101	342.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,43BH3@68525|delta/epsilon subdivisions,2X5KK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Adventurous gliding motility	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
CMS3_k127_6451558_0	1192034.CAP_5827	9.357e-181	582.0	COG1012@1|root,COG1012@2|Bacteria,1R528@1224|Proteobacteria,433YD@68525|delta/epsilon subdivisions,2X42A@28221|Deltaproteobacteria,2YY1Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.5	ko:K00129	ko00010,ko00340,ko00350,ko00360,ko00410,ko00980,ko00982,ko01100,ko01110,ko01120,ko05204,map00010,map00340,map00350,map00360,map00410,map00980,map00982,map01100,map01110,map01120,map05204	-	R00711,R00904,R02536,R02537,R02695,R02697,R03300,R03302,R04882,R04883,R04888,R04889,R04891,R04892,R04996,R07104,R08282,R08283,R08307	RC00047,RC00080,RC00242,RC01735	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_6451558_23	357808.RoseRS_3829	1.364e-37	163.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
CMS3_k127_6451558_10	502025.Hoch_2673	7.757e-94	327.0	COG0265@1|root,COG0265@2|Bacteria,1NE6G@1224|Proteobacteria,4321S@68525|delta/epsilon subdivisions,2WWD7@28221|Deltaproteobacteria,2YXPK@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_6451558_2	502025.Hoch_2654	1.858e-153	499.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,437G6@68525|delta/epsilon subdivisions,2X2NS@28221|Deltaproteobacteria,2YU1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_6451558_26	1254432.SCE1572_33300	1.089e-27	132.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
CMS3_k127_6451558_8	502025.Hoch_0070	3.363e-102	348.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6	-	-	Cadherin_3,DUF11,DUF4347,OmpA,Phenol_MetA_deg,TSP_3
CMS3_k127_6451558_18	502025.Hoch_0420	4.029e-55	201.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,431ED@68525|delta/epsilon subdivisions,2WWZ0@28221|Deltaproteobacteria,2YVD5@29|Myxococcales	28221|Deltaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS3_k127_6451558_5	502025.Hoch_0069	1.059e-128	425.0	COG0639@1|root,COG4103@1|root,COG0639@2|Bacteria,COG4103@2|Bacteria,1NJ9V@1224|Proteobacteria,438VE@68525|delta/epsilon subdivisions,2X417@28221|Deltaproteobacteria,2YXWH@29|Myxococcales	28221|Deltaproteobacteria	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_646237_8	502025.Hoch_0005	5.536e-137	476.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_646237_0	502025.Hoch_0004	0.0	1059.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2YU54@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS3_k127_646237_6	502025.Hoch_0003	3.496e-142	463.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,42SYJ@68525|delta/epsilon subdivisions,2WP80@28221|Deltaproteobacteria,2YV1Z@29|Myxococcales	28221|Deltaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CMS3_k127_646237_2	502025.Hoch_0002	2.842e-170	541.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2YUS5@29|Myxococcales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS3_k127_646237_1	502025.Hoch_0001	2.342e-191	610.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2YTT2@29|Myxococcales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS3_k127_646237_17	269799.Gmet_3564	1.564e-11	65.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,42WSU@68525|delta/epsilon subdivisions,2WSI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS3_k127_646237_16	391625.PPSIR1_35087	1.038e-13	77.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2YVYX@29|Myxococcales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS3_k127_646237_15	1123320.KB889730_gene6008	1.72e-20	99.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS3_k127_646237_5	502025.Hoch_6897	3.86e-143	480.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2YV0H@29|Myxococcales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS3_k127_646237_14	502025.Hoch_6896	1.024e-39	169.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria,2YW74@29|Myxococcales	28221|Deltaproteobacteria	S	R3H domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
CMS3_k127_646237_7	502025.Hoch_6895	1.234e-140	460.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,2YUQ3@29|Myxococcales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS3_k127_646237_9	502025.Hoch_6894	8.886e-115	383.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YUQI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_646237_3	502025.Hoch_6893	3.592e-169	542.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2YU21@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
CMS3_k127_646237_12	502025.Hoch_6892	6.561e-44	181.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,2Z324@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS3_k127_646237_13	502025.Hoch_6890	2.526e-41	173.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,42SB8@68525|delta/epsilon subdivisions,2WPKF@28221|Deltaproteobacteria,2YZGS@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS3_k127_646237_10	502025.Hoch_6889	8.095e-100	367.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS3_k127_646237_4	502025.Hoch_6888	3.881e-151	509.0	COG0745@1|root,COG0810@1|root,COG0745@2|Bacteria,COG0810@2|Bacteria,1NVZF@1224|Proteobacteria,42ZUK@68525|delta/epsilon subdivisions,2X7NR@28221|Deltaproteobacteria,2Z3H7@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,Response_reg
CMS3_k127_646237_11	502025.Hoch_6887	3.568e-88	327.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_6485012_8	1267535.KB906767_gene2128	8.687e-30	134.0	COG2227@1|root,COG2227@2|Bacteria,3Y8MU@57723|Acidobacteria	57723|Acidobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_6485012_5	1192034.CAP_0893	1.544e-71	253.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CMS3_k127_6485012_3	448385.sce4588	1.183e-127	425.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
CMS3_k127_6485012_4	502025.Hoch_4953	1.902e-126	412.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0D@68525|delta/epsilon subdivisions,2WRKF@28221|Deltaproteobacteria,2YV99@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS3_k127_6485012_1	502025.Hoch_4955	5.927e-216	699.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42QUN@68525|delta/epsilon subdivisions,2WN6Q@28221|Deltaproteobacteria,2YU60@29|Myxococcales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_6485012_10	502025.Hoch_4460	2.282e-14	88.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_6485012_2	502025.Hoch_4956	2.574e-149	479.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2YU7R@29|Myxococcales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS3_k127_6485012_7	502025.Hoch_4957	1.663e-48	180.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_6485012_15	867903.ThesuDRAFT_01273	0.0005863	49.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,3WDP3@538999|Clostridiales incertae sedis	186801|Clostridia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
CMS3_k127_6485012_13	319225.Plut_1571	4.221e-07	62.0	2E3QA@1|root,32YN8@2|Bacteria,1FFJG@1090|Chlorobi	1090|Chlorobi	M	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CMS3_k127_6485012_9	391625.PPSIR1_01572	4.673e-29	130.0	2DB6X@1|root,2Z7IP@2|Bacteria	391625.PPSIR1_01572|-	S	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6485012_0	502025.Hoch_4959	1.883e-273	869.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4399Y@68525|delta/epsilon subdivisions,2X4HE@28221|Deltaproteobacteria,2YZ0V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase; unclassified specificity.	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6510075_2	1313172.YM304_13760	3.503e-11	70.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
CMS3_k127_6510075_1	448385.sce1947	6.552e-29	130.0	2AJ4E@1|root,319NX@2|Bacteria,1Q3DF@1224|Proteobacteria,43950@68525|delta/epsilon subdivisions,2X4BA@28221|Deltaproteobacteria,2YYNQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6510075_0	1000565.METUNv1_00212	4.314e-62	221.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUM4@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6518426_2	502025.Hoch_3893	4.762e-72	250.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,2YUJZ@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome b subunit of the bc complex	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
CMS3_k127_6518426_5	502025.Hoch_3892	1.037e-48	183.0	2EQUD@1|root,33IE5@2|Bacteria,1N9A0@1224|Proteobacteria,43CZ1@68525|delta/epsilon subdivisions,2X878@28221|Deltaproteobacteria,2Z3MG@29|Myxococcales	1224|Proteobacteria	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS3_k127_6518426_6	314278.NB231_03600	4.563e-10	73.0	COG3746@1|root,COG3746@2|Bacteria,1RAJS@1224|Proteobacteria,1S3ID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CMS3_k127_6518426_7	448385.sce7858	0.0002967	48.0	2E5WH@1|root,330KI@2|Bacteria,1QAVR@1224|Proteobacteria,435BU@68525|delta/epsilon subdivisions,2WZPC@28221|Deltaproteobacteria,2Z2GK@29|Myxococcales	28221|Deltaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS3_k127_6518426_3	502025.Hoch_3591	8.236e-59	228.0	COG0637@1|root,COG0637@2|Bacteria,1RC0Z@1224|Proteobacteria,42Q7Y@68525|delta/epsilon subdivisions,2X5M6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS3_k127_6518426_0	502025.Hoch_3592	2.69e-148	487.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2Z2XK@29|Myxococcales	28221|Deltaproteobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_6518426_1	502025.Hoch_3593	4.809e-113	389.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria,2YUYZ@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_6520681_0	502025.Hoch_4615	0.0	1069.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WSCX@28221|Deltaproteobacteria,2YXM3@29|Myxococcales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TPR_14,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
CMS3_k127_6520681_7	502025.Hoch_4616	3.456e-86	312.0	COG1716@1|root,COG1716@2|Bacteria,1Q8QY@1224|Proteobacteria,437GG@68525|delta/epsilon subdivisions,2X2P3@28221|Deltaproteobacteria,2Z08U@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_6520681_4	502025.Hoch_4617	3.111e-111	376.0	COG1716@1|root,COG1716@2|Bacteria,1Q2GC@1224|Proteobacteria,4382T@68525|delta/epsilon subdivisions,2X0C6@28221|Deltaproteobacteria,2YVG7@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_6520681_12	717606.PaecuDRAFT_1199	0.0006629	48.0	COG3468@1|root,COG3468@2|Bacteria,1UJR4@1239|Firmicutes,4ITDS@91061|Bacilli,26UFP@186822|Paenibacillaceae	91061|Bacilli	MU	cell surface receptor IPT TIG domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
CMS3_k127_6520681_2	502025.Hoch_4510	6.622e-134	441.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YYKC@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_6520681_3	502025.Hoch_4584	1.029e-123	422.0	COG2227@1|root,COG2227@2|Bacteria,1QZT3@1224|Proteobacteria,42QXG@68525|delta/epsilon subdivisions,2WMWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_6520681_8	502025.Hoch_4583	6.685e-76	264.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria,2Z31F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS3_k127_6520681_1	502025.Hoch_4575	2.146e-257	798.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2YUPP@29|Myxococcales	28221|Deltaproteobacteria	H	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_6520681_9	502025.Hoch_4574	3.809e-57	201.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_6520681_5	391625.PPSIR1_12663	1.176e-107	370.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_6520681_10	391625.PPSIR1_12668	7.84e-53	196.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CMS3_k127_6520681_6	502025.Hoch_5596	2.996e-99	341.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
CMS3_k127_6535564_0	502025.Hoch_2720	1.847e-85	317.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria	1224|Proteobacteria	C	12 heme-binding sites	cbcC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_6535564_8	502025.Hoch_2611	4.502e-17	87.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2YW2T@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_6535564_3	483219.LILAB_05730	1.418e-38	158.0	COG3137@1|root,COG3137@2|Bacteria,1N2DE@1224|Proteobacteria,42W9S@68525|delta/epsilon subdivisions,2WTC1@28221|Deltaproteobacteria,2YVUC@29|Myxococcales	28221|Deltaproteobacteria	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
CMS3_k127_6535564_4	344747.PM8797T_11014	3.203e-34	144.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_6535564_10	470145.BACCOP_02670	3.138e-13	81.0	COG1331@1|root,COG1331@2|Bacteria,4NMU8@976|Bacteroidetes,2G0P6@200643|Bacteroidia,4AVB2@815|Bacteroidaceae	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
CMS3_k127_6535564_1	765420.OSCT_2368	1.056e-82	284.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi,376R3@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_6535564_7	1192034.CAP_3547	7.859e-21	109.0	COG3210@1|root,COG4786@1|root,COG5184@1|root,COG3210@2|Bacteria,COG4786@2|Bacteria,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_6535564_5	502025.Hoch_6490	1.426e-27	130.0	2C9M1@1|root,2ZSUM@2|Bacteria,1R0NN@1224|Proteobacteria,43CZC@68525|delta/epsilon subdivisions,2X87J@28221|Deltaproteobacteria,2Z3MM@29|Myxococcales	502025.Hoch_6490|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6535564_9	1038860.AXAP01000036_gene3341	7.102e-15	87.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria,3JUZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_65975_2	1160137.KB907308_gene6609	2.016e-33	138.0	COG2114@1|root,COG2114@2|Bacteria,2GJRI@201174|Actinobacteria,4FWTA@85025|Nocardiaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_65975_0	292459.STH1541	4.45e-91	310.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS3_k127_65975_3	1395587.P364_0108570	1.488e-13	85.0	COG1595@1|root,COG1595@2|Bacteria,1VIG7@1239|Firmicutes,4HTNK@91061|Bacilli,26U1D@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_65975_4	1211819.CALK01000028_gene1955	0.0001437	55.0	COG0454@1|root,COG0456@2|Bacteria,1UHVP@1239|Firmicutes,3VP5I@526524|Erysipelotrichia	526524|Erysipelotrichia	K	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
CMS3_k127_65975_1	502025.Hoch_4829	3.132e-44	164.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,2YUWI@29|Myxococcales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_6615038_1	1385519.N801_18290	4.37e-142	459.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4FIVS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_6615038_2	391165.GbCGDNIH1_0246	1.013e-81	284.0	COG0535@1|root,COG0535@2|Bacteria,1Q8U2@1224|Proteobacteria,2UYJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_6615038_0	404589.Anae109_3347	2.232e-166	554.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1NKQ0@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_6615038_3	743525.TSC_c11660	2.193e-25	116.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1WKSF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_6615038_4	595537.Varpa_4621	1.134e-21	99.0	COG2044@1|root,COG2044@2|Bacteria,1RGAZ@1224|Proteobacteria,2VYDA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_6616954_2	502025.Hoch_1928	2.435e-40	154.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CMS3_k127_6616954_4	502025.Hoch_1927	3.061e-32	136.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,2YVNJ@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS3_k127_6616954_5	378806.STAUR_1644	2.315e-21	104.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42V5H@68525|delta/epsilon subdivisions,2WQF4@28221|Deltaproteobacteria,2Z2ZJ@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ-1	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS3_k127_6616954_0	502025.Hoch_1925	1.712e-214	688.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_6616954_1	502025.Hoch_1924	3.562e-66	230.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,43B7N@68525|delta/epsilon subdivisions,2X6M3@28221|Deltaproteobacteria,2YVTK@29|Myxococcales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
CMS3_k127_6616954_3	502025.Hoch_1923	9.065e-40	156.0	COG0204@1|root,COG0204@2|Bacteria,1PZS9@1224|Proteobacteria,434JR@68525|delta/epsilon subdivisions,2WYX1@28221|Deltaproteobacteria,2Z0U7@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_6689832_30	502025.Hoch_4281	4.367e-06	48.0	COG1376@1|root,COG1376@2|Bacteria,1NKBB@1224|Proteobacteria,432T9@68525|delta/epsilon subdivisions,2WYN9@28221|Deltaproteobacteria,2YWNH@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS3_k127_6689832_35	358681.BBR47_21350	0.0001551	51.0	2C7XS@1|root,32WBT@2|Bacteria,1VC63@1239|Firmicutes,4HN5J@91061|Bacilli,272WM@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF3109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3109
CMS3_k127_6689832_12	1123023.JIAI01000009_gene1232	1.782e-70	254.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4EA1A@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6689832_6	1122939.ATUD01000012_gene3143	1.944e-146	474.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4CRE2@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_6689832_21	638302.HMPREF0908_1490	5.763e-27	117.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4H40Q@909932|Negativicutes	909932|Negativicutes	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS3_k127_6689832_3	215803.DB30_7820	4.656e-173	555.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1NN02@1224|Proteobacteria,433C0@68525|delta/epsilon subdivisions,2WX8B@28221|Deltaproteobacteria,2YUB3@29|Myxococcales	28221|Deltaproteobacteria	K	Pfam:DUF955	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_19,HTH_3,Peptidase_M78
CMS3_k127_6689832_0	502025.Hoch_0491	4.992e-301	960.0	COG0515@1|root,COG2909@1|root,COG0515@2|Bacteria,COG2909@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
CMS3_k127_6689832_1	502025.Hoch_0492	1.665e-184	591.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YYKF@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	pcaF	-	2.3.1.174,2.3.1.9	ko:K00626,ko:K07823	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_6689832_2	215803.DB30_3031	7.536e-179	592.0	COG0860@1|root,COG0860@2|Bacteria,1NTG0@1224|Proteobacteria,4390F@68525|delta/epsilon subdivisions,2X45H@28221|Deltaproteobacteria,2YYB1@29|Myxococcales	28221|Deltaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
CMS3_k127_6689832_27	1307761.L21SP2_1215	1.115e-08	69.0	COG0653@1|root,COG0653@2|Bacteria,2J5UR@203691|Spirochaetes	203691|Spirochaetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_6689832_7	502025.Hoch_6831	3.477e-118	398.0	COG3733@1|root,COG3733@2|Bacteria	2|Bacteria	Q	amine oxidase	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid
CMS3_k127_6689832_13	502025.Hoch_6816	3.596e-62	227.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,4330X@68525|delta/epsilon subdivisions,2WXN7@28221|Deltaproteobacteria,2Z0X5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6689832_11	1254432.SCE1572_07800	1.975e-76	279.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6689832_33	1324957.K933_02846	2.633e-05	58.0	COG3391@1|root,arCOG02562@2157|Archaea,2XX0P@28890|Euryarchaeota,23VHS@183963|Halobacteria	183963|Halobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
CMS3_k127_6689832_24	1330700.JQNC01000003_gene1982	1.502e-13	83.0	COG1470@1|root,COG3895@1|root,COG1470@2|Bacteria,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
CMS3_k127_6689832_18	502025.Hoch_6815	3.028e-37	142.0	COG3536@1|root,COG3536@2|Bacteria,1NICI@1224|Proteobacteria,435J1@68525|delta/epsilon subdivisions,2WZX3@28221|Deltaproteobacteria,2Z0WY@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS3_k127_6689832_9	502025.Hoch_6814	1.564e-91	317.0	COG0863@1|root,COG0863@2|Bacteria,1NCJF@1224|Proteobacteria,42WGQ@68525|delta/epsilon subdivisions,2WS8Q@28221|Deltaproteobacteria,2YVW5@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_6689832_20	502025.Hoch_4274	3.486e-35	148.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	-	ko:K02487,ko:K06596,ko:K07576	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	Autotransporter,Biotin_lipoyl,T2SSE_N
CMS3_k127_6689832_10	1210884.HG799462_gene7911	4.002e-79	293.0	COG0603@1|root,COG0603@2|Bacteria,2IXBD@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS3_k127_6689832_5	404589.Anae109_0600	8.127e-165	533.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria	1224|Proteobacteria	K	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD
CMS3_k127_6689832_31	1121428.DESHY_160129___1	9.362e-06	57.0	arCOG08608@1|root,32CXY@2|Bacteria,1V6CC@1239|Firmicutes,24AQP@186801|Clostridia,26284@186807|Peptococcaceae	186801|Clostridia	S	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Zn_dep_PLPC
CMS3_k127_6689832_29	1297742.A176_05132	5.163e-07	63.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
CMS3_k127_6689832_17	997884.HMPREF1068_02971	4.619e-42	175.0	COG0705@1|root,COG0705@2|Bacteria,4NP9G@976|Bacteroidetes,2FNME@200643|Bacteroidia,4AP39@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
CMS3_k127_6689832_15	1032480.MLP_15650	6.238e-50	200.0	COG1368@1|root,COG1368@2|Bacteria,2I7CJ@201174|Actinobacteria,4DUXQ@85009|Propionibacteriales	201174|Actinobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_6689832_25	1112204.GPOL_c28020	1.945e-11	70.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4GDW6@85026|Gordoniaceae	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
CMS3_k127_6689832_34	1254432.SCE1572_14985	4.587e-05	46.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTTN@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS3_k127_6689832_26	1254432.SCE1572_09970	5.237e-10	74.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	peaA	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Cytochrome_CBB3,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
CMS3_k127_6689832_14	760117.JN27_17805	4.413e-53	214.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,472VG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_6689832_4	1297742.A176_06458	3.027e-170	581.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria	1224|Proteobacteria	E	aminopeptidase N	-	-	3.4.11.14	ko:K01263	-	-	-	-	ko00000,ko01000	-	-	-	ERAP1_C,Peptidase_M1
CMS3_k127_6689832_23	502025.Hoch_6490	8.794e-17	94.0	2C9M1@1|root,2ZSUM@2|Bacteria,1R0NN@1224|Proteobacteria,43CZC@68525|delta/epsilon subdivisions,2X87J@28221|Deltaproteobacteria,2Z3MM@29|Myxococcales	502025.Hoch_6490|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6689832_28	391625.PPSIR1_00510	2.524e-08	68.0	COG1073@1|root,COG1073@2|Bacteria,1QZSS@1224|Proteobacteria,43CMQ@68525|delta/epsilon subdivisions,2X7UU@28221|Deltaproteobacteria,2YW90@29|Myxococcales	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6689832_8	502025.Hoch_3311	9.624e-97	341.0	COG0793@1|root,COG0793@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_6689832_19	502025.Hoch_5318	2.231e-35	137.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2YVDP@29|Myxococcales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS3_k127_6699326_5	502025.Hoch_0280	8.936e-86	293.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2199@2|Bacteria,1QWDQ@1224|Proteobacteria	1224|Proteobacteria	T	ggdef domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
CMS3_k127_6699326_3	502025.Hoch_0281	1.577e-131	437.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YUUX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_6699326_1	378806.STAUR_3626	4.786e-181	576.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,2YY78@29|Myxococcales	28221|Deltaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CMS3_k127_6699326_0	502025.Hoch_0319	1.938e-255	809.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria,2Z2WU@29|Myxococcales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
CMS3_k127_6699326_8	502025.Hoch_0318	4.525e-14	77.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
CMS3_k127_6699326_4	1192034.CAP_0326	1.483e-105	374.0	2DG6Z@1|root,2ZUS9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6699326_2	502025.Hoch_0317	1.435e-141	472.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Cu_amine_oxidN1,Tail_P2_I
CMS3_k127_6699326_6	1192034.CAP_2773	3.49e-45	183.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	B_lectin,SseB
CMS3_k127_6738541_1	502025.Hoch_4876	2.249e-133	432.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2YUID@29|Myxococcales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS3_k127_6738541_3	502025.Hoch_4875	9.272e-92	312.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2YVS3@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS3_k127_6738541_2	502025.Hoch_4874	2.482e-102	345.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2YVIS@29|Myxococcales	28221|Deltaproteobacteria	M	SurA N-terminal domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
CMS3_k127_6738541_4	502025.Hoch_4871	1.05e-76	269.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_6738541_5	502025.Hoch_6343	2.769e-45	183.0	COG2204@1|root,COG2204@2|Bacteria,1R0E3@1224|Proteobacteria,43CWJ@68525|delta/epsilon subdivisions,2WSIM@28221|Deltaproteobacteria,2YW6V@29|Myxococcales	2|Bacteria	T	response regulator	cpaE	-	2.7.13.3	ko:K02282,ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022,ko02035,ko02044	-	-	-	HATPase_c,HTH_18,HisKA,Response_reg
CMS3_k127_6738541_0	502025.Hoch_4100	1.518e-179	571.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,42NE7@68525|delta/epsilon subdivisions,2WJ77@28221|Deltaproteobacteria,2Z35P@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_6738541_6	1123487.KB892857_gene2411	2.901e-45	179.0	COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,2VKVW@28216|Betaproteobacteria,2KVV9@206389|Rhodocyclales	206389|Rhodocyclales	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
CMS3_k127_6738541_9	1192034.CAP_7221	4.15e-12	80.0	29XGE@1|root,30J6W@2|Bacteria,1R0E6@1224|Proteobacteria,43CWN@68525|delta/epsilon subdivisions,2WUSC@28221|Deltaproteobacteria,2Z1N5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6748062_5	502025.Hoch_3517	8.576e-56	201.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
CMS3_k127_6748062_7	1192034.CAP_4463	9.369e-16	89.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	peaA	-	1.4.9.1	ko:K08685	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Cytochrome_CBB3,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV
CMS3_k127_6748062_8	1218084.BBJK01000006_gene877	0.0005708	54.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,1K03X@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
CMS3_k127_6748062_6	1254432.SCE1572_34785	7.2e-43	179.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
CMS3_k127_6748062_0	502025.Hoch_3514	2.221e-240	757.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YZ4W@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_6748062_3	298654.FraEuI1c_3326	8.223e-94	320.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4EU68@85013|Frankiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_6748062_1	471852.Tcur_2187	1.211e-108	378.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4EGU0@85012|Streptosporangiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_6748062_2	378806.STAUR_0497	8.546e-99	329.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2WUIA@28221|Deltaproteobacteria,2YV7F@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
CMS3_k127_6748062_4	502025.Hoch_0157	3.845e-76	267.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WKU4@28221|Deltaproteobacteria,2Z2YS@29|Myxococcales	28221|Deltaproteobacteria	O	Hsp33 protein	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS3_k127_6754960_11	502025.Hoch_5365	5.954e-14	71.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,43BZ3@68525|delta/epsilon subdivisions,2X79U@28221|Deltaproteobacteria,2YU7U@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_6754960_13	1125863.JAFN01000001_gene830	5.822e-05	56.0	COG4188@1|root,COG4188@2|Bacteria,1QUVG@1224|Proteobacteria,43DFI@68525|delta/epsilon subdivisions,2X8MG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	COG1073 hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6754960_7	391625.PPSIR1_07263	8.096e-19	94.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6754960_9	1120950.KB892740_gene2603	4.172e-15	83.0	COG1309@1|root,COG1309@2|Bacteria,2HD07@201174|Actinobacteria,4DSG2@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6754960_10	1487953.JMKF01000042_gene2633	9.796e-15	89.0	COG3049@1|root,COG4188@1|root,COG3049@2|Bacteria,COG4188@2|Bacteria,1G5D4@1117|Cyanobacteria,1HASR@1150|Oscillatoriales	1117|Cyanobacteria	M	Alpha/beta hydrolase of unknown function (DUF1400)	-	-	-	-	-	-	-	-	-	-	-	-	AAT,DUF1400
CMS3_k127_6754960_5	290397.Adeh_0115	1.454e-63	238.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6754960_3	448385.sce0439	9.4e-105	361.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_6754960_6	1144275.COCOR_02883	2.488e-37	157.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,430Q8@68525|delta/epsilon subdivisions,2WVYQ@28221|Deltaproteobacteria,2YU06@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
CMS3_k127_6754960_0	502025.Hoch_2763	4.289e-161	526.0	COG1073@1|root,COG1073@2|Bacteria,1QTD8@1224|Proteobacteria,437WB@68525|delta/epsilon subdivisions,2WYPU@28221|Deltaproteobacteria,2YUPN@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6754960_1	502025.Hoch_2764	1.206e-141	461.0	2BJUS@1|root,32E6Z@2|Bacteria,1QTMY@1224|Proteobacteria,437ZY@68525|delta/epsilon subdivisions,2X39V@28221|Deltaproteobacteria,2YV11@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6754960_2	1120973.AQXL01000102_gene2649	1.999e-120	418.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,278QU@186823|Alicyclobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6754960_8	1408416.JNJT01000002_gene173	2.311e-17	93.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_6754960_4	1242864.D187_000579	4.674e-78	286.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,430Q8@68525|delta/epsilon subdivisions,2WVYQ@28221|Deltaproteobacteria,2YU06@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
CMS3_k127_6771461_17	1293054.HSACCH_00450	7.538e-18	86.0	COG2128@1|root,COG2128@2|Bacteria,1UVG3@1239|Firmicutes	1239|Firmicutes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6771461_18	1089550.ATTH01000002_gene47	1.766e-17	90.0	COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes,1FK4T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PA26 p53-induced protein (sestrin)	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6771461_5	391625.PPSIR1_04008	2.882e-114	385.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42NUP@68525|delta/epsilon subdivisions,2WKSD@28221|Deltaproteobacteria,2Z2YE@29|Myxococcales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-1	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS3_k127_6771461_13	502025.Hoch_2607	2.291e-43	169.0	COG3031@1|root,COG3031@2|Bacteria,1NB50@1224|Proteobacteria,42WPG@68525|delta/epsilon subdivisions,2WREX@28221|Deltaproteobacteria,2YVJ9@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CMS3_k127_6771461_0	502025.Hoch_0186	3.76e-267	833.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WUE6@28221|Deltaproteobacteria,2YTX9@29|Myxococcales	28221|Deltaproteobacteria	V	Efflux ABC transporter, permease ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_6771461_4	251221.35214720	5.898e-150	494.0	COG1164@1|root,COG1164@2|Bacteria,1G4TD@1117|Cyanobacteria	1117|Cyanobacteria	E	Peptidase family M3	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS3_k127_6771461_7	1184267.A11Q_2192	3.686e-99	338.0	COG3616@1|root,COG3616@2|Bacteria	2|Bacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
CMS3_k127_6771461_16	765912.Thimo_1242	7.736e-19	92.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria,1WXC2@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6771461_10	267608.RSc0992	3.811e-53	195.0	COG0625@1|root,COG3832@1|root,COG0625@2|Bacteria,COG3832@2|Bacteria,1RC4Y@1224|Proteobacteria,2VW3S@28216|Betaproteobacteria,1KH88@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gstF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1,GST_C,GST_N,GST_N_3
CMS3_k127_6771461_22	378806.STAUR_4890	6.824e-05	55.0	2ANK1@1|root,31DJ4@2|Bacteria,1QAV1@1224|Proteobacteria,435BA@68525|delta/epsilon subdivisions,2WZNP@28221|Deltaproteobacteria,2Z2FG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6771461_3	391625.PPSIR1_08511	4.284e-188	609.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS3_k127_6771461_1	886293.Sinac_1156	7.098e-204	689.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_6771461_8	502025.Hoch_0246	2.618e-83	294.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6771461_14	1254432.SCE1572_50145	5.313e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,1N4RS@1224|Proteobacteria,43E0K@68525|delta/epsilon subdivisions,2WZCJ@28221|Deltaproteobacteria,2Z1UN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6771461_21	448385.sce6997	2.167e-06	61.0	COG1729@1|root,COG3712@1|root,COG1729@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_6,WG_beta_rep
CMS3_k127_6771461_6	502025.Hoch_0219	3.649e-105	350.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2YWRT@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
CMS3_k127_6771461_2	269799.Gmet_3532	1.538e-192	614.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_6771461_23	432096.XP_003954735.1	0.0001503	53.0	COG0484@1|root,KOG0715@2759|Eukaryota,39JBD@33154|Opisthokonta,3Q3N5@4751|Fungi,3RKQ2@4890|Ascomycota,3RS1J@4891|Saccharomycetes,3RZ82@4893|Saccharomycetaceae	4751|Fungi	O	to Saccharomyces cerevisiae JEM1 (YJL073W)	-	GO:0000003,GO:0000741,GO:0000742,GO:0000746,GO:0000747,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0006997,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0016020,GO:0016043,GO:0019538,GO:0019941,GO:0019953,GO:0022414,GO:0030163,GO:0030433,GO:0033554,GO:0034975,GO:0034976,GO:0036503,GO:0042175,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044764,GO:0048284,GO:0050896,GO:0051082,GO:0051087,GO:0051603,GO:0051704,GO:0051716,GO:0071704,GO:0071840,GO:1901564,GO:1901565,GO:1901575,GO:1901698	-	ko:K09523	ko04141,ko05164,map04141,map05164	-	-	-	ko00000,ko00001,ko03110	-	-	-	DnaJ
CMS3_k127_6771461_9	1192034.CAP_3635	8.396e-62	236.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria,2YUVI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6771461_19	91464.S7335_1916	8.827e-15	83.0	COG2340@1|root,COG2931@1|root,COG2340@2|Bacteria,COG2931@2|Bacteria,1G4UZ@1117|Cyanobacteria,1H1QM@1129|Synechococcus	1117|Cyanobacteria	Q	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,HemolysinCabind
CMS3_k127_6771461_12	502025.Hoch_4908	4.452e-46	183.0	COG3744@1|root,COG3744@2|Bacteria,1NY7K@1224|Proteobacteria,4380D@68525|delta/epsilon subdivisions,2X3AF@28221|Deltaproteobacteria,2YV4N@29|Myxococcales	28221|Deltaproteobacteria	S	PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6771461_24	34740.HMEL002154-PA	0.0003446	53.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4430M@7088|Lepidoptera	33208|Metazoa	T	Epidermal growth factor-like domain.	dp	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA
CMS3_k127_6771461_15	391625.PPSIR1_13350	8.544e-24	118.0	COG2010@1|root,COG5297@1|root,COG2010@2|Bacteria,COG5297@2|Bacteria,1RCAB@1224|Proteobacteria,439EV@68525|delta/epsilon subdivisions,2X4Q2@28221|Deltaproteobacteria,2YZDM@29|Myxococcales	28221|Deltaproteobacteria	CG	Protein of unknown function (DUF1588)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3
CMS3_k127_6771461_25	1049564.TevJSym_cd00010	0.000602	53.0	COG4102@1|root,COG4102@2|Bacteria,1RG65@1224|Proteobacteria,1S41M@1236|Gammaproteobacteria,1J9VH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6773847_0	1125863.JAFN01000001_gene663	0.0	1622.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_6773847_1	1121920.AUAU01000008_gene1590	3.345e-111	381.0	COG0167@1|root,COG0167@2|Bacteria,3Y464@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_6773847_5	313606.M23134_02198	5.501e-12	69.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	CHAP,NLPC_P60
CMS3_k127_6773847_4	1192034.CAP_4811	7.585e-23	114.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	3.1.1.32,3.1.1.4	ko:K01058,ko:K07502	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	DUF2911,PEGA,T5orf172
CMS3_k127_6773847_3	502025.Hoch_2097	8.887e-35	140.0	COG0848@1|root,COG0848@2|Bacteria,1Q5DA@1224|Proteobacteria,42VMC@68525|delta/epsilon subdivisions,2X5N3@28221|Deltaproteobacteria,2Z0B1@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_6773847_2	502025.Hoch_2098	1.906e-59	213.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,42YY2@68525|delta/epsilon subdivisions,2WUI6@28221|Deltaproteobacteria,2Z0E8@29|Myxococcales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_6780818_4	448385.sce7465	6.032e-26	111.0	COG2010@1|root,COG2010@2|Bacteria,1QX4J@1224|Proteobacteria,437VA@68525|delta/epsilon subdivisions,2X34V@28221|Deltaproteobacteria,2YUNT@29|Myxococcales	28221|Deltaproteobacteria	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,Cu2_monooxygen
CMS3_k127_6780818_5	1134912.AJTV01000042_gene3570	1.704e-19	95.0	COG1309@1|root,COG1309@2|Bacteria,1N51S@1224|Proteobacteria,2UEHT@28211|Alphaproteobacteria,3706B@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6780818_0	1254432.SCE1572_22435	7.606e-146	499.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,42RYP@68525|delta/epsilon subdivisions,2WNDE@28221|Deltaproteobacteria,2YYGQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.99	ko:K19176	-	-	-	-	ko00000,ko01000	-	-	-	Amidase
CMS3_k127_6780818_2	411471.SUBVAR_05536	5.043e-140	467.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS3_k127_6780818_3	502025.Hoch_5964	1.237e-98	332.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,42ZS4@68525|delta/epsilon subdivisions,2WV20@28221|Deltaproteobacteria,2YUUK@29|Myxococcales	28221|Deltaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
CMS3_k127_6780818_1	502025.Hoch_5477	1.52e-140	453.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YWI7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
CMS3_k127_6790982_11	502025.Hoch_6088	1.162e-13	72.0	COG3172@1|root,COG3172@2|Bacteria	2|Bacteria	H	ATPase kinase involved in NAD metabolism	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CMS3_k127_6790982_0	502025.Hoch_4143	0.0	2712.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_7,TPR_8
CMS3_k127_6790982_12	378806.STAUR_3313	2.246e-10	72.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2XA07@28221|Deltaproteobacteria,2YZHM@29|Myxococcales	28221|Deltaproteobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PKD
CMS3_k127_6790982_8	448385.sce2055	1.944e-36	158.0	COG3055@1|root,COG3203@1|root,COG3055@2|Bacteria,COG3203@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6790982_6	502025.Hoch_4425	6.99e-37	140.0	COG4576@1|root,COG4576@2|Bacteria,1Q0YX@1224|Proteobacteria,434YC@68525|delta/epsilon subdivisions,2WZ99@28221|Deltaproteobacteria,2Z1MJ@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
CMS3_k127_6790982_9	502025.Hoch_4426	2.842e-30	126.0	COG4576@1|root,COG4576@2|Bacteria,1Q8QH@1224|Proteobacteria,4354D@68525|delta/epsilon subdivisions,2WZFG@28221|Deltaproteobacteria,2Z20V@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
CMS3_k127_6790982_3	502025.Hoch_4427	1.651e-83	285.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria,2YVQQ@29|Myxococcales	28221|Deltaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS3_k127_6790982_4	483219.LILAB_22310	1.098e-48	198.0	COG0515@1|root,COG0515@2|Bacteria	483219.LILAB_22310|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_6790982_7	926554.KI912637_gene3408	1.394e-36	159.0	COG3221@1|root,COG3221@2|Bacteria,1WIG6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_6790982_5	1144275.COCOR_02944	4.796e-39	150.0	COG3011@1|root,COG3011@2|Bacteria,1QDWV@1224|Proteobacteria,43EB9@68525|delta/epsilon subdivisions,2X07W@28221|Deltaproteobacteria,2Z012@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS3_k127_6790982_10	215803.DB30_4712	6.937e-23	102.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria,2Z0RF@29|Myxococcales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
CMS3_k127_6790982_1	886293.Sinac_1156	7.908e-305	975.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_6790982_2	1278073.MYSTI_03060	1.661e-92	321.0	2AIU5@1|root,319B7@2|Bacteria,1Q28R@1224|Proteobacteria,437VQ@68525|delta/epsilon subdivisions,2X359@28221|Deltaproteobacteria,2YUC5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6806320_3	404589.Anae109_0984	3.31e-150	503.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2YX41@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_6806320_0	502025.Hoch_5038	0.0	1043.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,42Z17@68525|delta/epsilon subdivisions,2WURE@28221|Deltaproteobacteria,2YUPJ@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CMS3_k127_6806320_2	502025.Hoch_4566	1.217e-207	665.0	COG4325@1|root,COG4325@2|Bacteria,1QKIM@1224|Proteobacteria,43411@68525|delta/epsilon subdivisions,2X4JG@28221|Deltaproteobacteria,2YZ4U@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
CMS3_k127_6806320_8	290397.Adeh_4239	6.141e-12	74.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
CMS3_k127_6806320_1	1254432.SCE1572_06465	8.308e-210	696.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_6806320_6	1411123.JQNH01000001_gene2362	6.517e-37	163.0	COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cyclic nucleotide-binding	MA20_09210	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV,cNMP_binding
CMS3_k127_6806320_5	502025.Hoch_6539	9.523e-52	199.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6806320_7	502025.Hoch_5430	1.501e-15	81.0	COG4783@1|root,COG4783@2|Bacteria,1QYGM@1224|Proteobacteria,43CCT@68525|delta/epsilon subdivisions,2X7NP@28221|Deltaproteobacteria,2Z3H5@29|Myxococcales	28221|Deltaproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_6815183_1	502025.Hoch_0049	7.153e-138	460.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,42SG1@68525|delta/epsilon subdivisions,2WP1E@28221|Deltaproteobacteria,2YUU8@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CMS3_k127_6815183_0	502025.Hoch_0050	8.126e-140	450.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YYJX@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6827342_5	309807.SRU_0977	3.603e-57	224.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6827342_6	1517681.HW45_08925	1.576e-06	61.0	COG2831@1|root,COG2831@2|Bacteria,1R2TR@1224|Proteobacteria,1SZV1@1236|Gammaproteobacteria,1Y2X7@135623|Vibrionales	135623|Vibrionales	U	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_6827342_0	502025.Hoch_2258	1.788e-200	643.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,2YWEJ@29|Myxococcales	28221|Deltaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS3_k127_6827342_4	502025.Hoch_2259	7.558e-66	243.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2WMSC@28221|Deltaproteobacteria,2YUZC@29|Myxococcales	28221|Deltaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS3_k127_6827342_1	502025.Hoch_2260	1.325e-110	367.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2YV00@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_6827342_2	502025.Hoch_2065	2.406e-91	312.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,2YVSY@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_6827342_3	502025.Hoch_5811	7.133e-84	302.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6830195_2	644966.Tmar_2139	8.876e-57	215.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	lysDH	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS3_k127_6830195_4	1515613.HQ37_04120	4.839e-15	80.0	2F643@1|root,33YND@2|Bacteria,4P41A@976|Bacteroidetes,2FSU4@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6830195_5	1236976.JCM16418_2659	2.024e-10	74.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,26T0E@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS3_k127_6830195_0	935948.KE386494_gene589	3.215e-112	386.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,42F3H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	msmX	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE,TOBE_2
CMS3_k127_6830195_1	215803.DB30_1694	1.098e-87	318.0	COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,43EXV@68525|delta/epsilon subdivisions,2X9AJ@28221|Deltaproteobacteria,2YZDJ@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10108,ko:K15770	ko02010,ko02030,map02010,map02030	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	SBP_bac_1
CMS3_k127_6830195_3	1278073.MYSTI_05944	2.581e-17	97.0	COG1175@1|root,COG2182@1|root,COG1175@2|Bacteria,COG2182@2|Bacteria,1MXKR@1224|Proteobacteria,42UM4@68525|delta/epsilon subdivisions,2WQPJ@28221|Deltaproteobacteria,2YUAR@29|Myxococcales	28221|Deltaproteobacteria	P	Sugar ABC transporter permease	malF	-	-	ko:K10109,ko:K15770,ko:K15771	ko02010,map02010	M00194,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22	-	-	BPD_transp_1,SBP_bac_8
CMS3_k127_6850497_8	1121935.AQXX01000142_gene2315	5.243e-34	152.0	COG1240@1|root,COG1240@2|Bacteria,1R4IW@1224|Proteobacteria,1SN40@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6850497_3	391625.PPSIR1_16285	2.385e-83	292.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2WM5N@28221|Deltaproteobacteria,2Z33T@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_6850497_16	715226.ABI_23970	1.199e-10	74.0	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,2UQ3C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_6850497_6	502025.Hoch_5114	3.985e-49	183.0	28XBK@1|root,2ZJ9G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6850497_4	1242864.D187_005496	1.245e-71	261.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,42UK8@68525|delta/epsilon subdivisions,2WQG7@28221|Deltaproteobacteria,2Z0U2@29|Myxococcales	28221|Deltaproteobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_transf_28,UDPGT
CMS3_k127_6850497_12	1996.JOFO01000042_gene5076	2.825e-24	115.0	COG0500@1|root,COG0500@2|Bacteria,2I2Y4@201174|Actinobacteria,4EGRS@85012|Streptosporangiales	201174|Actinobacteria	Q	Dimerisation domain	-	-	2.1.1.302	ko:K21377	-	-	-	-	ko00000,ko01000	-	-	-	Dimerisation2,Methyltransf_2
CMS3_k127_6850497_1	1254432.SCE1572_45120	1.588e-159	543.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,43AGY@68525|delta/epsilon subdivisions,2X5WX@28221|Deltaproteobacteria,2YWWR@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7
CMS3_k127_6850497_13	367299.JOEE01000008_gene437	5.642e-23	101.0	COG2329@1|root,COG2329@2|Bacteria,2GWCF@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_6850497_7	1297742.A176_02619	3.438e-45	171.0	COG1309@1|root,COG1309@2|Bacteria,1RITZ@1224|Proteobacteria,438VB@68525|delta/epsilon subdivisions,2WYC9@28221|Deltaproteobacteria,2Z0YF@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6850497_2	1297742.A176_02620	2.714e-129	433.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,42NEJ@68525|delta/epsilon subdivisions,2WM86@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_6850497_15	118168.MC7420_2604	5.183e-16	92.0	COG1216@1|root,COG1216@2|Bacteria,1G024@1117|Cyanobacteria,1HEWZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6850497_11	479435.Kfla_1169	1.767e-24	121.0	COG2706@1|root,COG2706@2|Bacteria,2IAVI@201174|Actinobacteria,4DWXA@85009|Propionibacteriales	201174|Actinobacteria	G	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_6850497_0	864069.MicloDRAFT_00008900	2.637e-178	570.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,1JS3J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0061 (SELO) family	MA20_28420	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
CMS3_k127_6850497_14	375286.mma_1868	6.071e-20	94.0	COG0500@1|root,COG0500@2|Bacteria,1R5D7@1224|Proteobacteria,2WH3J@28216|Betaproteobacteria,4792P@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS3_k127_6850497_5	653045.Strvi_6126	1.825e-67	246.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_6850497_9	1219077.VAZ01S_142_00030	2.696e-32	135.0	2DD81@1|root,2ZGZ6@2|Bacteria,1QKTK@1224|Proteobacteria,1TIYR@1236|Gammaproteobacteria,1Y01F@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6877167_1	1121935.AQXX01000127_gene1191	1.042e-68	258.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,1S91X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_6877167_6	1056820.KB900656_gene3627	1.78e-06	60.0	COG2010@1|root,COG2133@1|root,COG3386@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3386@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,2PNE9@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	C	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Cytochrome_CBB3,GSDH,PSCyt3,PSD3,PSD4,PSD5,SGL
CMS3_k127_6877167_3	215803.DB30_0686	5.505e-27	126.0	2AIUN@1|root,319BU@2|Bacteria,1Q29W@1224|Proteobacteria,437WR@68525|delta/epsilon subdivisions,2X36D@28221|Deltaproteobacteria,2YUHX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6878460_17	502025.Hoch_3449	4.074e-25	116.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,42U2Q@68525|delta/epsilon subdivisions,2WQK9@28221|Deltaproteobacteria,2YW3Q@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
CMS3_k127_6878460_3	502025.Hoch_3908	3.634e-143	461.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2YUGW@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS3_k127_6878460_15	240015.ACP_2054	1.443e-29	126.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria,2JJCJ@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS3_k127_6878460_12	502025.Hoch_3910	1.918e-47	174.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,2YVCN@29|Myxococcales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS3_k127_6878460_7	644282.Deba_3239	2.259e-80	276.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS3_k127_6878460_6	448385.sce6943	1.438e-80	299.0	COG0613@1|root,COG0613@2|Bacteria,1R4N5@1224|Proteobacteria,4384B@68525|delta/epsilon subdivisions,2X3E7@28221|Deltaproteobacteria,2YVP6@29|Myxococcales	28221|Deltaproteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6878460_2	1254432.SCE1572_37310	5.105e-146	473.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YX7D@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_6878460_0	502025.Hoch_0260	1.552e-213	670.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,42MB5@68525|delta/epsilon subdivisions,2WK7V@28221|Deltaproteobacteria,2YTWG@29|Myxococcales	28221|Deltaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
CMS3_k127_6878460_18	483219.LILAB_15385	5.877e-18	96.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_6878460_4	1254432.SCE1572_51745	1.134e-137	475.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_6878460_14	935548.KI912159_gene6276	2.495e-32	146.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria	1224|Proteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_6878460_5	518766.Rmar_1010	1.229e-86	310.0	COG0778@1|root,COG0778@2|Bacteria,4NQ04@976|Bacteroidetes	976|Bacteroidetes	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_6878460_10	502025.Hoch_3912	3.952e-62	226.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2YZQW@29|Myxococcales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS3_k127_6878460_11	502025.Hoch_3913	4.321e-58	207.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2YVJK@29|Myxococcales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS3_k127_6878460_8	502025.Hoch_3914	6.878e-80	280.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CHU_C,DUF11
CMS3_k127_6878460_9	502025.Hoch_2311	8.425e-74	270.0	COG0532@1|root,COG0532@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	pvpA	-	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	IF2_N
CMS3_k127_6878460_1	502025.Hoch_2310	2.551e-147	479.0	COG0446@1|root,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the GcvT family	-	-	1.4.99.5,1.5.3.1	ko:K00302,ko:K10815	ko00260,ko00460,ko01100,ko01110,map00260,map00460,map01100,map01110	-	R00374,R00610,R05704	RC00060,RC00557,RC02808	ko00000,ko00001,ko01000,ko02042	-	-	-	Fer2_4,Fer2_BFD,NAD_binding_8,Pyr_redox_2
CMS3_k127_6878460_16	502025.Hoch_2309	5.502e-27	126.0	COG0665@1|root,COG0665@2|Bacteria,1QAP8@1224|Proteobacteria,4357F@68525|delta/epsilon subdivisions,2X96I@28221|Deltaproteobacteria,2Z27U@29|Myxococcales	28221|Deltaproteobacteria	E	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
CMS3_k127_6878460_13	502025.Hoch_2308	5.124e-36	147.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria,2YUM5@29|Myxococcales	28221|Deltaproteobacteria	E	Sarcosine oxidase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
CMS3_k127_6900474_0	502025.Hoch_0265	6.4e-175	557.0	COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria,42Q9G@68525|delta/epsilon subdivisions,2WMIK@28221|Deltaproteobacteria,2Z23Z@29|Myxococcales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_6900474_4	1210884.HG799466_gene12383	4.83e-69	244.0	COG1526@1|root,COG1526@2|Bacteria,2IZ61@203682|Planctomycetes	203682|Planctomycetes	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS3_k127_6900474_1	502025.Hoch_1843	1.246e-112	399.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,42V1G@68525|delta/epsilon subdivisions,2WRCZ@28221|Deltaproteobacteria,2YWCA@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_6900474_5	502025.Hoch_6468	1.637e-43	181.0	2A465@1|root,30SR9@2|Bacteria,1PC3P@1224|Proteobacteria,4388A@68525|delta/epsilon subdivisions,2X1C4@28221|Deltaproteobacteria,2YW6K@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6900474_7	502025.Hoch_6469	2.352e-10	71.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_6469|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6900474_2	404589.Anae109_2327	3.425e-83	312.0	COG3506@1|root,COG5276@1|root,COG3506@2|Bacteria,COG5276@2|Bacteria,1Q8G3@1224|Proteobacteria,438JI@68525|delta/epsilon subdivisions,2X3U7@28221|Deltaproteobacteria,2YX4C@29|Myxococcales	28221|Deltaproteobacteria	U	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,TIG
CMS3_k127_6900474_8	391625.PPSIR1_18267	1.182e-05	59.0	2DSD6@1|root,33FM0@2|Bacteria,1PBXM@1224|Proteobacteria,43862@68525|delta/epsilon subdivisions,2X3FW@28221|Deltaproteobacteria,2YVX7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6900474_3	502025.Hoch_3412	1.828e-80	280.0	2CKRJ@1|root,304M1@2|Bacteria,1Q9ZX@1224|Proteobacteria,43DW9@68525|delta/epsilon subdivisions,2WZ1Q@28221|Deltaproteobacteria,2Z14P@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_69010_3	111781.Lepto7376_3266	5.536e-08	64.0	COG4188@1|root,COG4188@2|Bacteria,1G2BZ@1117|Cyanobacteria,1H6WB@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Alpha beta hydrolase of	-	-	-	-	-	-	-	-	-	-	-	-	DUF1400,Hydrolase_4,PAF-AH_p_II
CMS3_k127_69010_2	1219045.BV98_000192	1.302e-13	81.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,2U0VE@28211|Alphaproteobacteria,2KEAF@204457|Sphingomonadales	204457|Sphingomonadales	G	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_69010_0	7739.XP_002606139.1	8.716e-129	449.0	KOG1216@1|root,KOG1217@1|root,KOG1216@2759|Eukaryota,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,48CY1@7711|Chordata	33208|Metazoa	T	EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_3,EGF_CA,Lectin_C,TIL
CMS3_k127_6907029_1	502025.Hoch_3266	1.582e-20	93.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMIV@28221|Deltaproteobacteria,2YXJZ@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_6907029_0	404589.Anae109_1700	2.502e-37	154.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
CMS3_k127_6907919_3	502025.Hoch_2497	1.193e-87	298.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2YVC9@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS3_k127_6907919_4	502025.Hoch_2496	1.318e-76	271.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions,2WK7W@28221|Deltaproteobacteria,2YVDS@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS3_k127_6907919_1	502025.Hoch_2129	1.556e-140	459.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_6907919_2	1379698.RBG1_1C00001G1511	1.1e-133	443.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_6907919_6	1379698.RBG1_1C00001G1510	1.543e-46	193.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_6907919_7	1406840.Q763_13015	0.0001301	55.0	2A9IE@1|root,30YQS@2|Bacteria,4PCMJ@976|Bacteroidetes,1IBV6@117743|Flavobacteriia,2NXI3@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6907919_0	502025.Hoch_5631	7.697e-248	792.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,2YV5A@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
CMS3_k127_6907919_5	502025.Hoch_3264	1.626e-64	237.0	COG1196@1|root,COG1196@2|Bacteria,1Q5CV@1224|Proteobacteria,439J1@68525|delta/epsilon subdivisions,2X4VH@28221|Deltaproteobacteria,2Z08N@29|Myxococcales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_69097_0	502025.Hoch_0475	8.253e-91	313.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_69097_1	1242864.D187_000425	1.798e-21	100.0	2AIV6@1|root,319CD@2|Bacteria,1Q2BD@1224|Proteobacteria,437XV@68525|delta/epsilon subdivisions,2X37S@28221|Deltaproteobacteria,2YUR7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6922604_1	344747.PM8797T_21498	5.612e-93	325.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
CMS3_k127_6922604_2	1210908.HSB1_32250	1.032e-68	246.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_6922604_13	1121033.AUCF01000008_gene5649	2.371e-09	66.0	28P7A@1|root,30X9H@2|Bacteria,1NMJ8@1224|Proteobacteria,2UJXA@28211|Alphaproteobacteria,2JY82@204441|Rhodospirillales	204441|Rhodospirillales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS3_k127_6922604_4	502025.Hoch_3817	7.603e-54	199.0	COG0682@1|root,COG0682@2|Bacteria,1Q2R4@1224|Proteobacteria,438CQ@68525|delta/epsilon subdivisions,2WP0G@28221|Deltaproteobacteria,2YWK4@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_6922604_5	316055.RPE_1212	8.236e-51	190.0	COG3327@1|root,COG3327@2|Bacteria,1RABS@1224|Proteobacteria,2UDJW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG3327 Phenylacetic acid-responsive transcriptional repressor	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
CMS3_k127_6922604_8	247490.KSU1_D0395	8.491e-32	142.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_6922604_9	264462.Bd3094	5.048e-23	110.0	2FF6Q@1|root,3474Q@2|Bacteria,1P383@1224|Proteobacteria,431XS@68525|delta/epsilon subdivisions,2MUBV@213481|Bdellovibrionales,2WWB3@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6922604_11	1172188.KB911820_gene2657	6.525e-15	88.0	2EVIQ@1|root,33NYW@2|Bacteria,2IIIZ@201174|Actinobacteria,4FHQ3@85021|Intrasporangiaceae	201174|Actinobacteria	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
CMS3_k127_6922604_6	1192034.CAP_8147	9.293e-50	203.0	COG0613@1|root,COG0613@2|Bacteria,1R4N5@1224|Proteobacteria	1224|Proteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6922604_7	78245.Xaut_4256	6.812e-45	175.0	COG0599@1|root,COG0599@2|Bacteria,1RK66@1224|Proteobacteria,2UA98@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6922604_10	713586.KB900536_gene325	1.618e-22	109.0	COG0599@1|root,COG0599@2|Bacteria,1RK66@1224|Proteobacteria	1224|Proteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6922604_0	1380394.JADL01000001_gene2784	2.787e-123	408.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria,2TVNH@28211|Alphaproteobacteria,2JQZB@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_6922604_3	1254432.SCE1572_00985	5.471e-62	238.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
CMS3_k127_6928420_3	1192124.LIG30_2588	1.351e-24	104.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,1K32K@119060|Burkholderiaceae	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CMS3_k127_6928420_0	941449.dsx2_2410	3.44e-277	879.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2M7WE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS3_k127_6928420_1	448385.sce8727	2.018e-43	168.0	COG5184@1|root,COG5184@2|Bacteria,1R0E5@1224|Proteobacteria,43CWM@68525|delta/epsilon subdivisions,2X84N@28221|Deltaproteobacteria,2Z25N@29|Myxococcales	28221|Deltaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6928420_5	1380390.JIAT01000010_gene4001	5.7e-24	108.0	COG0589@1|root,COG1670@1|root,COG0589@2|Bacteria,COG1670@2|Bacteria,2HP6J@201174|Actinobacteria,4CQIP@84995|Rubrobacteria	84995|Rubrobacteria	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
CMS3_k127_6928420_2	1265313.HRUBRA_01315	2.977e-25	122.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,1T1H2@1236|Gammaproteobacteria,1J4VF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the PEP-utilizing enzyme family	ptsP	GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS3_k127_6928420_4	306281.AJLK01000030_gene1328	5.144e-24	104.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_6952135_2	448385.sce6263	1.968e-45	170.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
CMS3_k127_6952135_3	1192034.CAP_8672	7.059e-42	178.0	COG2905@1|root,COG3202@1|root,COG2905@2|Bacteria,COG3202@2|Bacteria,1RERN@1224|Proteobacteria	1224|Proteobacteria	T	Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_6952135_4	69042.WH5701_15611	1.803e-25	110.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
CMS3_k127_6952135_1	502025.Hoch_6702	4.153e-76	269.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42Q7D@68525|delta/epsilon subdivisions,2WN6T@28221|Deltaproteobacteria,2Z0I0@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS3_k127_6952135_0	391625.PPSIR1_03373	3.7e-170	566.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2YU2E@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_6960153_43	1487953.JMKF01000095_gene5153	3.35e-36	141.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_6960153_64	1317122.ATO12_20975	5.121e-09	62.0	2BP1A@1|root,32HRS@2|Bacteria,4PH5E@976|Bacteroidetes,1IHVG@117743|Flavobacteriia,2YJXA@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_55	1242864.D187_008444	1.685e-18	96.0	2AIUN@1|root,319BU@2|Bacteria,1Q29W@1224|Proteobacteria,437WR@68525|delta/epsilon subdivisions,2X36D@28221|Deltaproteobacteria,2YUHX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_16	1144275.COCOR_03484	8.894e-98	337.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,PEGA,Pkinase
CMS3_k127_6960153_44	391625.PPSIR1_03368	5.927e-34	145.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria,2YXSM@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CMS3_k127_6960153_23	404589.Anae109_4402	8.017e-81	281.0	COG4427@1|root,COG4427@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
CMS3_k127_6960153_9	448385.sce7527	5.496e-181	578.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,432XE@68525|delta/epsilon subdivisions,2WYHS@28221|Deltaproteobacteria,2YU0E@29|Myxococcales	28221|Deltaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_47	448385.sce7526	2.157e-27	124.0	COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,43BB8@68525|delta/epsilon subdivisions,2X6QE@28221|Deltaproteobacteria,2YVUR@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
CMS3_k127_6960153_69	1198114.AciX9_1045	1.145e-05	57.0	COG3266@1|root,COG3266@2|Bacteria,3Y99V@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Collagen triple helix	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
CMS3_k127_6960153_13	1385935.N836_32270	2.369e-135	441.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1H8KG@1150|Oscillatoriales	1117|Cyanobacteria	M	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_6960153_40	502025.Hoch_3159	3.337e-40	153.0	COG0517@1|root,COG0517@2|Bacteria,1QAJW@1224|Proteobacteria,42XWB@68525|delta/epsilon subdivisions,2WTBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_6960153_45	502025.Hoch_3160	4.669e-31	137.0	COG0517@1|root,COG0517@2|Bacteria,1QAJV@1224|Proteobacteria,43557@68525|delta/epsilon subdivisions,2WZG5@28221|Deltaproteobacteria,2Z22P@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_6960153_33	502025.Hoch_4569	8.989e-58	216.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6960153_37	1487953.JMKF01000050_gene1926	8.771e-53	199.0	2CCCK@1|root,2Z7UH@2|Bacteria,1GGQS@1117|Cyanobacteria,1HH0S@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_5	331869.BAL199_27766	3.989e-232	728.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6960153_19	331869.BAL199_27751	8.848e-90	303.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,4BS4B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_6960153_26	1500301.JQMF01000023_gene5581	5.094e-76	274.0	COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2V5U1@28211|Alphaproteobacteria,4BGB5@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
CMS3_k127_6960153_11	502025.Hoch_2360	3.672e-142	467.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2YWS4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS3_k127_6960153_0	502025.Hoch_2359	0.0	1439.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_6960153_17	1192034.CAP_4649	1.11e-90	320.0	COG2931@1|root,COG2931@2|Bacteria,1PG5F@1224|Proteobacteria,43F2Q@68525|delta/epsilon subdivisions,2X35A@28221|Deltaproteobacteria,2YY8H@29|Myxococcales	28221|Deltaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_21	1242864.D187_005808	1.634e-87	304.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,4372N@68525|delta/epsilon subdivisions,2X1UJ@28221|Deltaproteobacteria,2Z0EY@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_6960153_8	502025.Hoch_4262	2.066e-181	596.0	COG0025@1|root,COG1762@1|root,COG0025@2|Bacteria,COG1762@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_6960153_41	1869.MB27_04020	7.293e-40	152.0	2CHCP@1|root,32S5R@2|Bacteria,2IRB0@201174|Actinobacteria,4DEPC@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS3_k127_6960153_28	639282.DEFDS_1120	5.449e-66	250.0	COG1127@1|root,COG1127@2|Bacteria,2GEYW@200930|Deferribacteres	200930|Deferribacteres	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_6960153_30	56780.SYN_00410	9.928e-66	249.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2MQE7@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	PFAM ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_6960153_25	909613.UO65_4795	6.287e-79	274.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,4E086@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	echA21	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_6960153_70	398525.KB900701_gene7348	0.0001312	53.0	COG1054@1|root,COG2900@1|root,COG1054@2|Bacteria,COG2900@2|Bacteria,1MUFV@1224|Proteobacteria,2TUB5@28211|Alphaproteobacteria,3JRTF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
CMS3_k127_6960153_20	391625.PPSIR1_39475	2.314e-88	306.0	COG2114@1|root,COG2114@2|Bacteria,1MWHK@1224|Proteobacteria,439X7@68525|delta/epsilon subdivisions,2X1UA@28221|Deltaproteobacteria,2YZZF@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_6960153_66	1297570.MESS4_830016	4.002e-08	66.0	29WNZ@1|root,30I9V@2|Bacteria,1RD7D@1224|Proteobacteria,2U7N7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_7	448385.sce2507	1.034e-184	590.0	COG0300@1|root,COG1028@1|root,COG0300@2|Bacteria,COG1028@2|Bacteria,1R4BM@1224|Proteobacteria,42PS2@68525|delta/epsilon subdivisions,2WJJK@28221|Deltaproteobacteria,2YU82@29|Myxococcales	28221|Deltaproteobacteria	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_6960153_48	404589.Anae109_2605	1.995e-26	122.0	2E2DB@1|root,32XI5@2|Bacteria,1N20T@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4262)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4262
CMS3_k127_6960153_60	1192034.CAP_3825	5.012e-13	75.0	29ZQ8@1|root,30MQZ@2|Bacteria,1QB4G@1224|Proteobacteria,435E7@68525|delta/epsilon subdivisions,2WZRU@28221|Deltaproteobacteria,2Z2M5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_6960153_63	448385.sce2670	4.617e-10	72.0	2DQ41@1|root,334MP@2|Bacteria,1QWJG@1224|Proteobacteria	1224|Proteobacteria	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1
CMS3_k127_6960153_51	1202768.JROF01000003_gene3080	9.936e-21	96.0	COG0824@1|root,arCOG01137@2157|Archaea,2XXHC@28890|Euryarchaeota,23VWV@183963|Halobacteria	183963|Halobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_6960153_29	1123242.JH636436_gene523	8.971e-66	244.0	COG1413@1|root,COG3303@1|root,COG1413@2|Bacteria,COG3303@2|Bacteria,2J0SN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_6960153_46	72019.SARC_12327T0	3.819e-28	124.0	2D1RT@1|root,2S4WQ@2759|Eukaryota	2759|Eukaryota	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_6960153_71	1380387.JADM01000010_gene3842	0.0005063	50.0	COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,1XHM4@135619|Oceanospirillales	135619|Oceanospirillales	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
CMS3_k127_6960153_39	1254432.SCE1572_25125	1.27e-42	165.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_6960153_52	649349.Lbys_0105	6.564e-20	96.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_6960153_50	1168067.JAGP01000001_gene144	4.734e-21	106.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_6960153_32	502025.Hoch_4794	1.382e-64	231.0	COG3770@1|root,COG3770@2|Bacteria,1QA7G@1224|Proteobacteria,43DYC@68525|delta/epsilon subdivisions,2WZ6W@28221|Deltaproteobacteria,2Z1GB@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-insensitive murein endopeptidase	-	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
CMS3_k127_6960153_1	502025.Hoch_6627	0.0	1052.0	COG0791@1|root,COG0791@2|Bacteria,1MU8A@1224|Proteobacteria,43C67@68525|delta/epsilon subdivisions,2X7GE@28221|Deltaproteobacteria,2YYT0@29|Myxococcales	28221|Deltaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
CMS3_k127_6960153_67	1227500.C494_13116	9.441e-08	61.0	COG1475@1|root,arCOG00622@2157|Archaea,2XTYJ@28890|Euryarchaeota,23S7H@183963|Halobacteria	183963|Halobacteria	K	COG0517 FOG CBS domain	cbs10	-	-	-	-	-	-	-	-	-	-	-	CBS,ParBc
CMS3_k127_6960153_27	1121920.AUAU01000002_gene1999	3.763e-72	259.0	COG3174@1|root,COG3174@2|Bacteria,3Y601@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
CMS3_k127_6960153_34	1116375.VEJY3_18331	2.739e-55	202.0	COG3911@1|root,COG3911@2|Bacteria,1RBSG@1224|Proteobacteria,1S31D@1236|Gammaproteobacteria,1XZZB@135623|Vibrionales	135623|Vibrionales	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CMS3_k127_6960153_65	91464.S7335_5339	2.456e-08	67.0	COG2133@1|root,COG2911@1|root,COG2931@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,1GJ0F@1117|Cyanobacteria,1H1MZ@1129|Synechococcus	1117|Cyanobacteria	Q	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_42	448385.sce3099	2.207e-37	163.0	2AIUZ@1|root,319C5@2|Bacteria,1Q2AQ@1224|Proteobacteria,437XB@68525|delta/epsilon subdivisions,2X9R0@28221|Deltaproteobacteria,2Z0BZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_10	1454004.AW11_03331	1.768e-144	484.0	COG1226@1|root,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria	1224|Proteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS3_k127_6960153_3	83406.HDN1F_15990	9.867e-283	923.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,1J4JG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit	-	-	5.4.99.2,5.4.99.63	ko:K01847,ko:K14447	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS3_k127_6960153_31	83406.HDN1F_15980	4.345e-65	233.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,1RP15@1236|Gammaproteobacteria,1J4Q4@118884|unclassified Gammaproteobacteria	1224|Proteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_6960153_36	1443111.JASG01000004_gene3633	2.369e-53	203.0	COG0738@1|root,COG0738@2|Bacteria,1QVNU@1224|Proteobacteria,2UMIH@28211|Alphaproteobacteria,3ZVC6@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_6960153_56	313628.LNTAR_00630	3.572e-18	90.0	2FHFB@1|root,3499D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6960153_54	1449069.JMLO01000011_gene2494	7.959e-19	95.0	COG2186@1|root,COG2186@2|Bacteria,2I90D@201174|Actinobacteria,4FYCG@85025|Nocardiaceae	201174|Actinobacteria	K	FCD	mce2R	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS3_k127_6960153_6	502025.Hoch_3323	1.127e-193	633.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,42YBA@68525|delta/epsilon subdivisions,2WUP5@28221|Deltaproteobacteria,2YX31@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CMS3_k127_6960153_18	266265.Bxe_A2766	4.02e-90	308.0	COG2267@1|root,COG2267@2|Bacteria,1MUFB@1224|Proteobacteria,2VRAQ@28216|Betaproteobacteria,1K14I@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS3_k127_6960153_49	222534.KB893719_gene1048	1.858e-22	104.0	COG5514@1|root,COG5514@2|Bacteria,2IS68@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
CMS3_k127_6960153_72	1122604.JONR01000025_gene4566	0.0006314	45.0	COG5514@1|root,COG5514@2|Bacteria,1MX90@1224|Proteobacteria,1S9SH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
CMS3_k127_6960153_2	886293.Sinac_1156	4.225e-285	918.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_6960153_4	502025.Hoch_3585	4.469e-256	812.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42Q9Q@68525|delta/epsilon subdivisions,2WKCR@28221|Deltaproteobacteria,2YZDF@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_6960153_62	313603.FB2170_05360	6.091e-11	76.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2PGZ8@252356|Maribacter	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_6960153_15	448385.sce6715	2.269e-121	419.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,42NT4@68525|delta/epsilon subdivisions,2WJFM@28221|Deltaproteobacteria,2YYSM@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_6960153_12	1192034.CAP_4178	4.996e-141	460.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,42PZC@68525|delta/epsilon subdivisions,2WK59@28221|Deltaproteobacteria,2YWAH@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_6960153_22	448385.sce6717	1.054e-86	325.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QF5@68525|delta/epsilon subdivisions,2WK2K@28221|Deltaproteobacteria,2YXMZ@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6960153_14	448385.sce6718	3.265e-122	405.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,42PK1@68525|delta/epsilon subdivisions,2WJ65@28221|Deltaproteobacteria,2Z12Q@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS3_k127_6960153_24	215803.DB30_3565	7.797e-80	278.0	COG1960@1|root,COG1960@2|Bacteria,1N2Q3@1224|Proteobacteria,439IY@68525|delta/epsilon subdivisions,2X4VE@28221|Deltaproteobacteria,2YZPD@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_M
CMS3_k127_6960153_53	1217718.ALOU01000005_gene1436	7.028e-19	94.0	COG1309@1|root,COG1309@2|Bacteria,1RIG0@1224|Proteobacteria,2VYKM@28216|Betaproteobacteria,1K9ZF@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6960153_58	247634.GPB2148_958	5.352e-16	89.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,1S1Y5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_6960153_35	502025.Hoch_2461	1.234e-53	201.0	COG1051@1|root,COG1051@2|Bacteria,1RJAP@1224|Proteobacteria,42SFP@68525|delta/epsilon subdivisions,2WPBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_6960153_38	1121935.AQXX01000127_gene1191	2.007e-44	181.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,1S91X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_6978024_14	1123228.AUIH01000010_gene3984	9.686e-11	72.0	COG4102@1|root,COG4102@2|Bacteria,1RG65@1224|Proteobacteria,1S41M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6978024_13	1192034.CAP_0290	1.27e-16	85.0	2AYRE@1|root,31QWF@2|Bacteria,1QNFJ@1224|Proteobacteria,43DZP@68525|delta/epsilon subdivisions,2X93E@28221|Deltaproteobacteria,2Z1PQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6978024_4	383372.Rcas_0264	1.338e-59	222.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6978024_7	290397.Adeh_4042	1.999e-34	149.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS3_k127_6978024_12	290397.Adeh_2167	1.167e-19	97.0	COG3945@1|root,COG3945@2|Bacteria,1QAVJ@1224|Proteobacteria,435BP@68525|delta/epsilon subdivisions,2WZP5@28221|Deltaproteobacteria,2Z2G7@29|Myxococcales	28221|Deltaproteobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_6978024_0	448385.sce8281	5.696e-191	612.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YYIW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_6978024_3	502025.Hoch_4714	1.374e-77	269.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,43A6F@68525|delta/epsilon subdivisions,2XA3X@28221|Deltaproteobacteria,2Z18A@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
CMS3_k127_6978024_5	927677.ALVU02000001_gene1366	1.048e-54	219.0	COG2761@1|root,COG2761@2|Bacteria,1G41Q@1117|Cyanobacteria	1117|Cyanobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_6978024_6	1388763.O165_023050	1.546e-43	175.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1YY5S@136845|Pseudomonas putida group	1236|Gammaproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	iAF1260.b3502,iB21_1397.B21_03304,iBWG_1329.BWG_3192,iECBD_1354.ECBD_0238,iECB_1328.ECB_03351,iECDH10B_1368.ECDH10B_3678,iECDH1ME8569_1439.ECDH1ME8569_3381,iECD_1391.ECD_03351,iECH74115_1262.ECH74115_4851,iECIAI1_1343.ECIAI1_3649,iECO103_1326.ECO103_4229,iECO111_1330.ECO111_4311,iECO26_1355.ECO26_4590,iECSE_1348.ECSE_3768,iECSP_1301.ECSP_4482,iECs_1301.ECs4374,iETEC_1333.ETEC_3749,iEcDH1_1363.EcDH1_0212,iEcE24377_1341.EcE24377A_3985,iEcHS_1320.EcHS_A3704,iEcolC_1368.EcolC_0214,iG2583_1286.G2583_4228,iJO1366.b3502,iSFV_1184.SFV_3514,iSF_1195.SF3535,iS_1188.S4233,iUMNK88_1353.UMNK88_4279,iY75_1357.Y75_RS19690,iZ_1308.Z4904	ArsB
CMS3_k127_6978024_9	1380393.JHVP01000003_gene836	8.801e-28	129.0	COG1785@1|root,COG1785@2|Bacteria,2GM8A@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS3_k127_6978024_8	378806.STAUR_4740	2.325e-29	131.0	COG2315@1|root,COG2315@2|Bacteria,1Q2G4@1224|Proteobacteria,4382J@68525|delta/epsilon subdivisions,2X3CK@28221|Deltaproteobacteria,2YVFB@29|Myxococcales	28221|Deltaproteobacteria	S	YjbR	difB	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS3_k127_6978024_10	1242864.D187_000127	5.905e-26	117.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_6978024_2	391625.PPSIR1_38761	3.518e-82	303.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,43AJ6@68525|delta/epsilon subdivisions,2X5ZG@28221|Deltaproteobacteria,2Z37W@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_7,zf-HC2
CMS3_k127_6978024_11	502025.Hoch_4124	3.099e-21	100.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS3_k127_6978024_1	1167006.UWK_00244	5.917e-88	309.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42NID@68525|delta/epsilon subdivisions,2WJ4P@28221|Deltaproteobacteria,2MJ6G@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CMS3_k127_6981146_7	502025.Hoch_2081	8.61e-12	66.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2Z1X0@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_6981146_6	502025.Hoch_2082	6.044e-25	122.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	Abi
CMS3_k127_6981146_1	690850.Desaf_1438	6.487e-186	596.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2M96K@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS3_k127_6981146_3	502025.Hoch_6442	8.078e-144	475.0	COG1305@1|root,COG1305@2|Bacteria,1R0BY@1224|Proteobacteria,43DTA@68525|delta/epsilon subdivisions,2X8VQ@28221|Deltaproteobacteria,2Z0KI@29|Myxococcales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_6981146_2	261292.Nit79A3_1296	6.096e-181	573.0	COG1960@1|root,COG1960@2|Bacteria,1R9RG@1224|Proteobacteria,2WDMG@28216|Betaproteobacteria,3745S@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6981146_4	261292.Nit79A3_1297	5.576e-143	477.0	COG3221@1|root,COG3221@2|Bacteria,1N92V@1224|Proteobacteria,2WBUH@28216|Betaproteobacteria,373TX@32003|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
CMS3_k127_6981146_0	261292.Nit79A3_1298	6.284e-189	612.0	COG0425@1|root,COG0425@2|Bacteria,1R8DP@1224|Proteobacteria,2WFJB@28216|Betaproteobacteria,373Y3@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_6981146_5	1254432.SCE1572_34165	7.289e-30	124.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_34165|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_699750_5	290317.Cpha266_0782	7.776e-22	108.0	28J1N@1|root,2Z8YI@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS3_k127_699750_3	314345.SPV1_08993	9.362e-58	206.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria	1224|Proteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CMS3_k127_699750_0	886293.Sinac_5055	6.07e-281	897.0	COG3002@1|root,COG3002@2|Bacteria,2IX3X@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
CMS3_k127_699750_1	1210884.HG799468_gene13812	9.801e-109	373.0	COG1009@1|root,COG1009@2|Bacteria,2IXWW@203682|Planctomycetes	203682|Planctomycetes	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L)	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
CMS3_k127_699750_2	1123242.JH636434_gene5376	1.066e-61	241.0	COG1008@1|root,COG1008@2|Bacteria,2IXKM@203682|Planctomycetes	203682|Planctomycetes	C	NADH ubiquinone oxidoreductase subunit 4 (Chain M)	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_699750_4	1394178.AWOO02000009_gene4351	6.707e-51	192.0	COG0596@1|root,COG0596@2|Bacteria,2I6D8@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7099885_6	946362.XP_004991535.1	1.154e-06	59.0	2D01Y@1|root,2SCG5@2759|Eukaryota,38TBM@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Reprolysin_3
CMS3_k127_7099885_0	502025.Hoch_3426	7.152e-202	653.0	COG1331@1|root,COG1331@2|Bacteria,1NF9Z@1224|Proteobacteria,43AQ1@68525|delta/epsilon subdivisions,2WXG6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7099885_3	391625.PPSIR1_10555	2.675e-95	335.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7099885_2	391625.PPSIR1_39635	1.01e-140	454.0	28H6T@1|root,2Z7J4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7099885_1	502025.Hoch_3753	2.571e-197	639.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2YTVH@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS3_k127_7111612_4	67332.FM21_28975	5.11e-05	56.0	COG1474@1|root,COG1474@2|Bacteria,2HM4W@201174|Actinobacteria	201174|Actinobacteria	LO	P-loop Domain of unknown function (DUF2791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2791
CMS3_k127_7111612_1	1192868.CAIU01000038_gene4413	1.35e-60	215.0	COG1670@1|root,COG1670@2|Bacteria,1RHBD@1224|Proteobacteria,2U925@28211|Alphaproteobacteria,43R77@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_7111612_2	425104.Ssed_2792	2.049e-49	184.0	COG1670@1|root,COG1670@2|Bacteria,1PEMZ@1224|Proteobacteria,1TAG3@1236|Gammaproteobacteria,2QCS4@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_7111612_0	378806.STAUR_7238	8.052e-94	328.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_7111612_3	1210908.HSB1_23050	1.963e-26	112.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_7154399_0	502025.Hoch_4050	4.794e-129	421.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2YTWZ@29|Myxococcales	28221|Deltaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS3_k127_7154399_1	502025.Hoch_4051	3.815e-74	255.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42PHT@68525|delta/epsilon subdivisions,2WKTH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS3_k127_7167311_3	404589.Anae109_2321	3.494e-79	275.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_7167311_0	1144275.COCOR_07231	9.105e-92	340.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX4C@1224|Proteobacteria,43BWW@68525|delta/epsilon subdivisions,2X77N@28221|Deltaproteobacteria,2YXG1@29|Myxococcales	28221|Deltaproteobacteria	DEZ	TIGRFAM cysteine-rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_7167311_1	404589.Anae109_3722	1.716e-85	320.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,LRR_5,Peptidase_C1,TIG
CMS3_k127_7167311_2	404589.Anae109_2321	1.272e-80	278.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_7167311_5	1163408.UU9_01304	9.504e-05	53.0	COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,1MXHM@1224|Proteobacteria,1RMWB@1236|Gammaproteobacteria,1X4W4@135614|Xanthomonadales	135614|Xanthomonadales	P	Iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FTR1
CMS3_k127_7167311_4	1121946.AUAX01000026_gene6225	2.809e-45	186.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4DAX8@85008|Micromonosporales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,GerE,Guanylate_cyc,Trans_reg_C
CMS3_k127_7211909_16	1144275.COCOR_05538	4.545e-05	51.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_7211909_11	796606.BMMGA3_07950	1.517e-38	164.0	COG0584@1|root,COG3540@1|root,COG0584@2|Bacteria,COG3540@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli,1ZCIE@1386|Bacillus	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.3.1,3.1.4.46	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	M00126	R01030,R01470,R04620	RC00017,RC00425	ko00000,ko00001,ko00002,ko01000	-	-	-	GDPD
CMS3_k127_7211909_3	926554.KI912640_gene1366	5.517e-118	391.0	COG1960@1|root,COG1960@2|Bacteria,1WMGQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7211909_8	713587.THITH_07800	7.515e-65	234.0	COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,1RYP5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS3_k127_7211909_9	446462.Amir_0405	1.561e-57	220.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4DZRE@85010|Pseudonocardiales	201174|Actinobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_7211909_6	1502851.FG93_04310	4.513e-72	262.0	COG2358@1|root,COG2358@2|Bacteria,1Q1N8@1224|Proteobacteria,2V9C0@28211|Alphaproteobacteria,3K4DF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
CMS3_k127_7211909_15	1125863.JAFN01000001_gene2807	6.774e-06	55.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS3_k127_7211909_0	886293.Sinac_1156	2.918e-256	835.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_7211909_14	1254432.SCE1572_00520	9.196e-14	87.0	COG4409@1|root,COG4409@2|Bacteria,1NUCS@1224|Proteobacteria,43DX9@68525|delta/epsilon subdivisions,2X90E@28221|Deltaproteobacteria,2Z1A2@29|Myxococcales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF4185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185
CMS3_k127_7211909_4	1121920.AUAU01000014_gene2803	3.173e-108	371.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_7211909_1	502025.Hoch_4573	1.814e-194	648.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
CMS3_k127_7211909_10	1254432.SCE1572_34990	7.475e-54	210.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,43AY5@68525|delta/epsilon subdivisions,2X6CI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_7211909_12	1040983.AXAE01000001_gene2641	3.23e-29	127.0	COG3791@1|root,COG3791@2|Bacteria,1NC41@1224|Proteobacteria	1224|Proteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_7211909_5	502025.Hoch_5278	4.166e-74	263.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
CMS3_k127_7211909_2	118166.JH976537_gene3474	1.82e-184	585.0	COG0436@1|root,COG0436@2|Bacteria,1G0NC@1117|Cyanobacteria,1H74E@1150|Oscillatoriales	1117|Cyanobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_7211909_13	502025.Hoch_4468	9.321e-16	89.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K02487,ko:K03832,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02000,ko02022,ko02035	2.C.1.1	-	-	CarbopepD_reg_2,FabA,KAsynt_C_assoc,Ketoacyl-synt_C,TonB_2,TonB_C,ketoacyl-synt
CMS3_k127_7216756_26	1192034.CAP_1583	4.761e-07	55.0	COG1633@1|root,COG1633@2|Bacteria,1R8DF@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7216756_21	1415780.JPOG01000001_gene2869	1.428e-19	97.0	COG1309@1|root,COG1309@2|Bacteria,1N5HZ@1224|Proteobacteria,1SANK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_7216756_18	448385.sce9226	1.811e-35	143.0	COG5031@1|root,COG5031@2|Bacteria,1NKS8@1224|Proteobacteria,434J5@68525|delta/epsilon subdivisions,2WYWC@28221|Deltaproteobacteria,2Z0SR@29|Myxococcales	28221|Deltaproteobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7216756_28	237368.SCABRO_00346	3.701e-05	54.0	COG2010@1|root,COG2010@2|Bacteria,2IYC2@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_7216756_4	1089553.Tph_c26440	1.598e-112	386.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
CMS3_k127_7216756_19	502025.Hoch_3130	1.767e-32	136.0	2E7B7@1|root,331UM@2|Bacteria,1NB58@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7216756_8	502025.Hoch_0547	2.457e-93	332.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TPR_12
CMS3_k127_7216756_10	502025.Hoch_5471	6.381e-72	258.0	COG1595@1|root,COG1595@2|Bacteria,1Q2GH@1224|Proteobacteria,43830@68525|delta/epsilon subdivisions,2X0DG@28221|Deltaproteobacteria,2YVH2@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-binding regulatory protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_7216756_23	391625.PPSIR1_01587	2.845e-16	91.0	COG1409@1|root,COG3656@1|root,COG1409@2|Bacteria,COG3656@2|Bacteria	2|Bacteria	N	Periplasmic Protein	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS3_k127_7216756_12	391625.PPSIR1_02146	1.216e-55	212.0	COG3325@1|root,COG3325@2|Bacteria,1NQ14@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7216756_6	96561.Dole_0409	1.01e-106	368.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS3_k127_7216756_3	391625.PPSIR1_15265	2.931e-125	406.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
CMS3_k127_7216756_5	400682.PAC_15714731	1.752e-111	388.0	2E0GU@1|root,2S7X7@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7216756_17	502025.Hoch_2396	5.267e-37	161.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2YU0A@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_7216756_2	1333998.M2A_2240	4.783e-131	434.0	COG1960@1|root,COG1960@2|Bacteria,1R3VD@1224|Proteobacteria,2U2WQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7216756_9	1248760.ANFZ01000014_gene2098	2.018e-77	273.0	COG1960@1|root,COG1960@2|Bacteria,1R7M8@1224|Proteobacteria,2TS45@28211|Alphaproteobacteria,2KCQD@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS3_k127_7216756_27	246197.MXAN_5043	3.998e-06	60.0	COG1506@1|root,COG2911@1|root,COG1506@2|Bacteria,COG2911@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
CMS3_k127_7216756_24	70448.A0A090M5K8	3.359e-09	66.0	KOG1940@1|root,KOG1940@2759|Eukaryota,37INM@33090|Viridiplantae,34IZN@3041|Chlorophyta	3041|Chlorophyta	O	CHY zinc finger	-	-	-	ko:K16276	-	-	-	-	ko00000,ko04121	-	-	-	Hemerythrin,zf-CHY,zf-RING_2,zinc_ribbon_6
CMS3_k127_7216756_0	985054.JQEZ01000003_gene1287	0.0	1290.0	COG0452@1|root,COG2105@1|root,COG0452@2|Bacteria,COG2105@2|Bacteria,1NZ4M@1224|Proteobacteria,2V21Z@28211|Alphaproteobacteria,4ND25@97050|Ruegeria	28211|Alphaproteobacteria	H	Phytochelatin synthase	-	-	-	-	-	-	-	-	-	-	-	-	Ank_4,Flavoprotein,GGACT,Phytochelatin
CMS3_k127_7216756_13	1380394.JADL01000008_gene3484	1.349e-54	211.0	COG2114@1|root,COG2114@2|Bacteria,1MY09@1224|Proteobacteria,2U2KA@28211|Alphaproteobacteria,2JX68@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_7216756_7	406552.NJ7G_2116	2.802e-106	355.0	COG1653@1|root,arCOG00151@2157|Archaea,2Y2AY@28890|Euryarchaeota,23Z4Y@183963|Halobacteria	183963|Halobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7216756_1	886293.Sinac_1156	1.483e-307	988.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_7216756_25	865937.Gilli_0558	1.568e-08	68.0	COG1520@1|root,COG2304@1|root,COG3391@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG3391@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia,2P5SV@244698|Gillisia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
CMS3_k127_7216756_16	930169.B5T_00157	1.643e-41	177.0	COG4188@1|root,COG4188@2|Bacteria,1Q4K6@1224|Proteobacteria,1S7GC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7216756_29	215803.DB30_8034	0.0003849	51.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_7216756_15	290397.Adeh_4051	3.9e-44	186.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,42SBM@68525|delta/epsilon subdivisions,2WQ24@28221|Deltaproteobacteria,2Z0M5@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS3_k127_7216756_11	502025.Hoch_2723	1.169e-59	214.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2Z0NX@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
CMS3_k127_7246477_9	290397.Adeh_1993	2.359e-34	134.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_7246477_1	1121918.ARWE01000001_gene445	1.979e-128	430.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_7246477_16	204669.Acid345_0759	1.518e-12	72.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS3_k127_7246477_0	269799.Gmet_0597	2.851e-173	560.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_7246477_13	748247.AZKH_2875	1.728e-22	112.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2WF5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7246477_14	8932.XP_005512985.1	4.909e-17	98.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BAFT@33208|Metazoa,3CRZB@33213|Bilateria,485Y1@7711|Chordata,48WDE@7742|Vertebrata,4GHY1@8782|Aves	33208|Metazoa	T	neurogenic locus notch	NOTCH1	GO:0000003,GO:0000122,GO:0000139,GO:0000278,GO:0000578,GO:0000902,GO:0000904,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0000988,GO:0000989,GO:0001012,GO:0001067,GO:0001076,GO:0001190,GO:0001503,GO:0001525,GO:0001568,GO:0001570,GO:0001649,GO:0001654,GO:0001655,GO:0001666,GO:0001667,GO:0001669,GO:0001700,GO:0001701,GO:0001708,GO:0001709,GO:0001726,GO:0001736,GO:0001738,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0001756,GO:0001763,GO:0001816,GO:0001822,GO:0001837,GO:0001840,GO:0001889,GO:0001894,GO:0001932,GO:0001933,GO:0001934,GO:0001942,GO:0001944,GO:0001947,GO:0002009,GO:0002011,GO:0002040,GO:0002051,GO:0002052,GO:0002064,GO:0002065,GO:0002066,GO:0002067,GO:0002085,GO:0002164,GO:0002165,GO:0002193,GO:0002213,GO:0002237,GO:0002244,GO:0002376,GO:0002437,GO:0002520,GO:0002682,GO:0002683,GO:0002684,GO:0002790,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003143,GO:0003151,GO:0003156,GO:0003157,GO:0003158,GO:0003160,GO:0003161,GO:0003162,GO:0003169,GO:0003170,GO:0003171,GO:0003174,GO:0003176,GO:0003177,GO:0003178,GO:0003179,GO:0003180,GO:0003181,GO:0003182,GO:0003183,GO:0003184,GO:0003188,GO:0003190,GO:0003192,GO:0003197,GO:0003198,GO:0003203,GO:0003205,GO:0003206,GO:0003207,GO:0003208,GO:0003209,GO:0003211,GO:0003213,GO:0003214,GO:0003215,GO:0003219,GO:0003222,GO:0003229,GO:0003230,GO:0003231,GO:0003241,GO:0003250,GO:0003252,GO:0003256,GO:0003264,GO:0003266,GO:0003270,GO:0003272,GO:0003273,GO:0003279,GO:0003281,GO:0003330,GO:0003332,GO:0003344,GO:0003348,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0004857,GO:0004888,GO:0005102,GO:0005112,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005768,GO:0005770,GO:0005783,GO:0005789,GO:0005794,GO:0005796,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0005911,GO:0005912,GO:0006109,GO:0006110,GO:0006139,GO:0006140,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006725,GO:0006807,GO:0006810,GO:0006915,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007050,GO:0007154,GO:0007155,GO:0007157,GO:0007162,GO:0007163,GO:0007164,GO:0007165,GO:0007166,GO:0007219,GO:0007221,GO:0007267,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007292,GO:0007293,GO:0007297,GO:0007298,GO:0007304,GO:0007306,GO:0007308,GO:0007309,GO:0007314,GO:0007346,GO:0007350,GO:0007351,GO:0007368,GO:0007386,GO:0007389,GO:0007391,GO:0007398,GO:0007399,GO:0007400,GO:0007403,GO:0007405,GO:0007409,GO:0007411,GO:0007417,GO:0007419,GO:0007420,GO:0007422,GO:0007423,GO:0007424,GO:0007440,GO:0007442,GO:0007443,GO:0007444,GO:0007446,GO:0007447,GO:0007449,GO:0007450,GO:0007451,GO:0007455,GO:0007460,GO:0007464,GO:0007472,GO:0007473,GO:0007474,GO:0007476,GO:0007478,GO:0007480,GO:0007483,GO:0007484,GO:0007485,GO:0007492,GO:0007498,GO:0007507,GO:0007517,GO:0007519,GO:0007521,GO:0007548,GO:0007552,GO:0007560,GO:0007568,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008045,GO:0008052,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008284,GO:0008285,GO:0008340,GO:0008347,GO:0008356,GO:0008358,GO:0008407,GO:0008544,GO:0008587,GO:0008593,GO:0008595,GO:0009058,GO:0009059,GO:0009306,GO:0009605,GO:0009607,GO:0009608,GO:0009611,GO:0009617,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009799,GO:0009855,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009912,GO:0009913,GO:0009948,GO:0009950,GO:0009952,GO:0009953,GO:0009954,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0009994,GO:0009996,GO:0010001,GO:0010002,GO:0010033,GO:0010160,GO:0010243,GO:0010259,GO:0010453,GO:0010454,GO:0010455,GO:0010467,GO:0010468,GO:0010470,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010594,GO:0010596,GO:0010604,GO:0010605,GO:0010611,GO:0010614,GO:0010623,GO:0010628,GO:0010629,GO:0010631,GO:0010632,GO:0010633,GO:0010646,GO:0010647,GO:0010648,GO:0010717,GO:0010718,GO:0010720,GO:0010721,GO:0010810,GO:0010812,GO:0010830,GO:0010832,GO:0010927,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0014013,GO:0014014,GO:0014015,GO:0014016,GO:0014017,GO:0014019,GO:0014031,GO:0014070,GO:0014706,GO:0014741,GO:0014743,GO:0014807,GO:0014855,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0016202,GO:0016324,GO:0016330,GO:0016331,GO:0016333,GO:0016348,GO:0016360,GO:0016477,GO:0016525,GO:0017145,GO:0017157,GO:0017158,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019827,GO:0019899,GO:0019953,GO:0021510,GO:0021514,GO:0021515,GO:0021517,GO:0021522,GO:0021523,GO:0021531,GO:0021536,GO:0021538,GO:0021700,GO:0021781,GO:0021915,GO:0021953,GO:0021986,GO:0022008,GO:0022402,GO:0022404,GO:0022405,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022416,GO:0022603,GO:0022607,GO:0022610,GO:0022612,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030054,GO:0030097,GO:0030100,GO:0030111,GO:0030139,GO:0030141,GO:0030154,GO:0030155,GO:0030178,GO:0030182,GO:0030216,GO:0030234,GO:0030278,GO:0030279,GO:0030323,GO:0030324,GO:0030326,GO:0030334,GO:0030335,GO:0030336,GO:0030510,GO:0030513,GO:0030514,GO:0030539,GO:0030703,GO:0030707,GO:0030708,GO:0030713,GO:0030718,GO:0030720,GO:0030808,GO:0030811,GO:0030850,GO:0030855,GO:0030856,GO:0030857,GO:0030858,GO:0030900,GO:0031016,GO:0031017,GO:0031069,GO:0031090,GO:0031099,GO:0031100,GO:0031175,GO:0031224,GO:0031226,GO:0031252,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031344,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031490,GO:0031960,GO:0031974,GO:0031981,GO:0031982,GO:0031984,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032270,GO:0032354,GO:0032495,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032633,GO:0032774,GO:0032835,GO:0032870,GO:0032872,GO:0032873,GO:0032879,GO:0032940,GO:0032989,GO:0032990,GO:0032991,GO:0033002,GO:0033036,GO:0033554,GO:0033993,GO:0034641,GO:0034645,GO:0034654,GO:0034698,GO:0035003,GO:0035050,GO:0035051,GO:0035107,GO:0035108,GO:0035112,GO:0035113,GO:0035114,GO:0035116,GO:0035120,GO:0035126,GO:0035137,GO:0035148,GO:0035153,GO:0035155,GO:0035157,GO:0035161,GO:0035162,GO:0035163,GO:0035165,GO:0035166,GO:0035167,GO:0035168,GO:0035170,GO:0035171,GO:0035172,GO:0035203,GO:0035204,GO:0035214,GO:0035215,GO:0035218,GO:0035220,GO:0035222,GO:0035239,GO:0035265,GO:0035272,GO:0035282,GO:0035285,GO:0035295,GO:0035315,GO:0035850,GO:0035886,GO:0035904,GO:0035907,GO:0035914,GO:0035924,GO:0036003,GO:0036011,GO:0036099,GO:0036293,GO:0036294,GO:0036335,GO:0038023,GO:0040007,GO:0040008,GO:0040009,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040019,GO:0040034,GO:0042051,GO:0042060,GO:0042063,GO:0042067,GO:0042127,GO:0042175,GO:0042221,GO:0042246,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042386,GO:0042387,GO:0042461,GO:0042462,GO:0042478,GO:0042480,GO:0042490,GO:0042491,GO:0042493,GO:0042592,GO:0042633,GO:0042659,GO:0042660,GO:0042661,GO:0042663,GO:0042675,GO:0042676,GO:0042686,GO:0042688,GO:0042689,GO:0042691,GO:0042692,GO:0042693,GO:0042706,GO:0042733,GO:0042886,GO:0042981,GO:0042995,GO:0043009,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043296,GO:0043408,GO:0043409,GO:0043410,GO:0043467,GO:0043470,GO:0043502,GO:0043523,GO:0043525,GO:0043535,GO:0043537,GO:0043565,GO:0043583,GO:0043588,GO:0043618,GO:0043620,GO:0043696,GO:0043697,GO:0043900,GO:0043902,GO:0043903,GO:0044057,GO:0044085,GO:0044087,GO:0044092,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044703,GO:0044782,GO:0045069,GO:0045070,GO:0045165,GO:0045168,GO:0045177,GO:0045184,GO:0045314,GO:0045316,GO:0045445,GO:0045446,GO:0045463,GO:0045465,GO:0045466,GO:0045468,GO:0045595,GO:0045596,GO:0045597,GO:0045601,GO:0045603,GO:0045604,GO:0045605,GO:0045606,GO:0045607,GO:0045608,GO:0045610,GO:0045611,GO:0045612,GO:0045613,GO:0045614,GO:0045616,GO:0045618,GO:0045631,GO:0045632,GO:0045661,GO:0045662,GO:0045664,GO:0045665,GO:0045667,GO:0045668,GO:0045682,GO:0045683,GO:0045684,GO:0045685,GO:0045686,GO:0045687,GO:0045747,GO:0045765,GO:0045786,GO:0045787,GO:0045844,GO:0045892,GO:0045893,GO:0045920,GO:0045926,GO:0045927,GO:0045931,GO:0045934,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0045955,GO:0045967,GO:0045995,GO:0046328,GO:0046329,GO:0046331,GO:0046425,GO:0046427,GO:0046483,GO:0046530,GO:0046532,GO:0046533,GO:0046552,GO:0046578,GO:0046579,GO:0046620,GO:0046622,GO:0046661,GO:0046666,GO:0046667,GO:0046782,GO:0046843,GO:0046903,GO:0046982,GO:0046983,GO:0048052,GO:0048056,GO:0048103,GO:0048138,GO:0048139,GO:0048190,GO:0048232,GO:0048259,GO:0048337,GO:0048468,GO:0048469,GO:0048477,GO:0048505,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048534,GO:0048542,GO:0048545,GO:0048546,GO:0048562,GO:0048563,GO:0048565,GO:0048568,GO:0048569,GO:0048580,GO:0048581,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048592,GO:0048598,GO:0048599,GO:0048608,GO:0048609,GO:0048619,GO:0048634,GO:0048636,GO:0048638,GO:0048639,GO:0048644,GO:0048645,GO:0048646,GO:0048663,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048708,GO:0048709,GO:0048710,GO:0048711,GO:0048713,GO:0048715,GO:0048729,GO:0048730,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048738,GO:0048749,GO:0048754,GO:0048762,GO:0048803,GO:0048805,GO:0048806,GO:0048808,GO:0048812,GO:0048839,GO:0048844,GO:0048845,GO:0048856,GO:0048858,GO:0048859,GO:0048863,GO:0048864,GO:0048865,GO:0048867,GO:0048869,GO:0048870,GO:0048871,GO:0048872,GO:0048873,GO:0048934,GO:0048935,GO:0048936,GO:0050434,GO:0050663,GO:0050673,GO:0050678,GO:0050679,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050790,GO:0050792,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0050922,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051056,GO:0051057,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051145,GO:0051147,GO:0051148,GO:0051153,GO:0051154,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051271,GO:0051272,GO:0051301,GO:0051489,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051890,GO:0051960,GO:0051961,GO:0051962,GO:0055001,GO:0055006,GO:0055008,GO:0055010,GO:0055016,GO:0055017,GO:0055021,GO:0055023,GO:0055024,GO:0055025,GO:0055123,GO:0060019,GO:0060038,GO:0060039,GO:0060043,GO:0060045,GO:0060089,GO:0060113,GO:0060120,GO:0060173,GO:0060249,GO:0060250,GO:0060251,GO:0060253,GO:0060255,GO:0060271,GO:0060284,GO:0060288,GO:0060289,GO:0060317,GO:0060322,GO:0060379,GO:0060411,GO:0060412,GO:0060415,GO:0060419,GO:0060420,GO:0060421,GO:0060429,GO:0060485,GO:0060491,GO:0060512,GO:0060525,GO:0060528,GO:0060537,GO:0060538,GO:0060541,GO:0060548,GO:0060560,GO:0060561,GO:0060562,GO:0060563,GO:0060571,GO:0060581,GO:0060582,GO:0060627,GO:0060740,GO:0060742,GO:0060768,GO:0060828,GO:0060837,GO:0060840,GO:0060841,GO:0060842,GO:0060843,GO:0060947,GO:0060948,GO:0060956,GO:0060972,GO:0060973,GO:0060976,GO:0060977,GO:0060979,GO:0060982,GO:0061005,GO:0061008,GO:0061053,GO:0061061,GO:0061138,GO:0061311,GO:0061314,GO:0061326,GO:0061331,GO:0061333,GO:0061344,GO:0061351,GO:0061371,GO:0061382,GO:0061383,GO:0061384,GO:0061418,GO:0061419,GO:0061437,GO:0061440,GO:0061448,GO:0061458,GO:0061525,GO:0061564,GO:0062012,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070161,GO:0070167,GO:0070168,GO:0070302,GO:0070303,GO:0070372,GO:0070374,GO:0070482,GO:0070848,GO:0070887,GO:0070925,GO:0070986,GO:0071310,GO:0071363,GO:0071371,GO:0071372,GO:0071453,GO:0071456,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072001,GO:0072002,GO:0072006,GO:0072007,GO:0072008,GO:0072009,GO:0072012,GO:0072017,GO:0072044,GO:0072073,GO:0072080,GO:0072089,GO:0072091,GO:0072109,GO:0072132,GO:0072143,GO:0072144,GO:0072148,GO:0072358,GO:0072359,GO:0072602,GO:0080090,GO:0080134,GO:0080135,GO:0090049,GO:0090051,GO:0090068,GO:0090090,GO:0090092,GO:0090100,GO:0090101,GO:0090130,GO:0090132,GO:0090257,GO:0090287,GO:0090288,GO:0090304,GO:0090596,GO:0090598,GO:0097084,GO:0097150,GO:0097159,GO:0097223,GO:0097435,GO:0097485,GO:0097659,GO:0097708,GO:0098588,GO:0098590,GO:0098609,GO:0098727,GO:0098742,GO:0098772,GO:0098773,GO:0098791,GO:0098796,GO:0098797,GO:0098827,GO:0099503,GO:0120025,GO:0120031,GO:0120032,GO:0120035,GO:0120036,GO:0120039,GO:0140110,GO:1900087,GO:1900371,GO:1900542,GO:1901187,GO:1901189,GO:1901201,GO:1901213,GO:1901214,GO:1901216,GO:1901342,GO:1901343,GO:1901360,GO:1901362,GO:1901363,GO:1901522,GO:1901532,GO:1901533,GO:1901576,GO:1901652,GO:1901698,GO:1901700,GO:1901861,GO:1901863,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902263,GO:1902337,GO:1902339,GO:1902531,GO:1902532,GO:1902533,GO:1902679,GO:1902680,GO:1902692,GO:1902742,GO:1902806,GO:1902808,GO:1903053,GO:1903054,GO:1903224,GO:1903305,GO:1903306,GO:1903506,GO:1903507,GO:1903508,GO:1903530,GO:1903531,GO:1903578,GO:1903670,GO:1903671,GO:1903706,GO:1903707,GO:1903847,GO:1903849,GO:1903900,GO:1903902,GO:1904018,GO:1904238,GO:1904747,GO:1904748,GO:1904892,GO:1904894,GO:1905207,GO:1905314,GO:1905456,GO:1905457,GO:1905651,GO:1905653,GO:1905770,GO:1905772,GO:1905902,GO:1905904,GO:1990837,GO:2000026,GO:2000027,GO:2000043,GO:2000045,GO:2000047,GO:2000048,GO:2000112,GO:2000113,GO:2000136,GO:2000137,GO:2000145,GO:2000146,GO:2000147,GO:2000177,GO:2000179,GO:2000181,GO:2000209,GO:2000241,GO:2000380,GO:2000382,GO:2000543,GO:2000648,GO:2000736,GO:2000737,GO:2000811,GO:2000826,GO:2000973,GO:2000974,GO:2000980,GO:2000981,GO:2001013,GO:2001026,GO:2001027,GO:2001141,GO:2001169	-	ko:K02599,ko:K20994	ko01522,ko04320,ko04330,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002	-	-	-	Ank,Ank_2,Ank_5,DUF3454,EGF,EGF_CA,NOD,NODP,Notch,hEGF
CMS3_k127_7246477_12	1125863.JAFN01000001_gene1912	7.389e-26	127.0	COG3880@1|root,COG3880@2|Bacteria,1NT4T@1224|Proteobacteria,42Z7E@68525|delta/epsilon subdivisions,2WUQB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM UvrB UvrC protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
CMS3_k127_7246477_15	1120958.AULD01000005_gene1651	7.96e-15	87.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4FM4B@85023|Microbacteriaceae	201174|Actinobacteria	O	ResB-like family	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS3_k127_7246477_4	443144.GM21_3558	2.219e-80	277.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS3_k127_7246477_24	566461.SSFG_00091	0.0006626	53.0	2B7WC@1|root,3213B@2|Bacteria,2H50F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7246477_19	546268.NEISUBOT_05368	1.931e-10	74.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,2KPGY@206351|Neisseriales	206351|Neisseriales	O	cytochrome c-type biogenesis protein CcsB	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS3_k127_7246477_2	58123.JOFJ01000015_gene4408	8.395e-113	391.0	COG0220@1|root,COG0220@2|Bacteria,2IEHH@201174|Actinobacteria	201174|Actinobacteria	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7246477_7	373994.Riv7116_6903	3.222e-38	166.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1HMK8@1161|Nostocales	1117|Cyanobacteria	H	PFAM Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_7246477_8	443143.GM18_0616	1.025e-34	150.0	COG4346@1|root,COG4346@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT,PMT_2,PMT_4TMC
CMS3_k127_7246477_10	1121430.JMLG01000010_gene218	3.563e-34	140.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,261N0@186807|Peptococcaceae	186801|Clostridia	N	PFAM OmpA	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS3_k127_7246477_11	1415780.JPOG01000001_gene845	2.876e-29	132.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1X322@135614|Xanthomonadales	135614|Xanthomonadales	N	Flagellar motor protein	motB1	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS3_k127_7246477_6	1121413.JMKT01000008_gene1392	1.922e-45	173.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria,2M7ZH@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CMS3_k127_7246477_20	688269.Theth_0037	1.393e-08	67.0	COG1536@1|root,COG1536@2|Bacteria,2GCFH@200918|Thermotogae	200918|Thermotogae	N	flagellar motor switch protein FliG	fliG	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046982,GO:0046983	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
CMS3_k127_7246477_5	1191523.MROS_0147	1.538e-54	209.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
CMS3_k127_7246477_17	1131269.AQVV01000004_gene570	1.83e-12	75.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS3_k127_7246477_21	391625.PPSIR1_31553	2.453e-07	57.0	2ESCQ@1|root,33JXH@2|Bacteria,1P9JE@1224|Proteobacteria,4325U@68525|delta/epsilon subdivisions,2WXM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7246477_22	331678.Cphamn1_2259	1.773e-06	51.0	COG2710@1|root,COG2710@2|Bacteria,1FDDI@1090|Chlorobi	1090|Chlorobi	F	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex	bchB	-	1.3.7.7	ko:K04039	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
CMS3_k127_7246477_3	247490.KSU1_C1622	5.671e-100	336.0	COG1730@1|root,COG1730@2|Bacteria	2|Bacteria	O	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
CMS3_k127_7266581_8	502025.Hoch_2186	4.36e-82	275.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CMS3_k127_7266581_7	338963.Pcar_2350	2.263e-88	311.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,43SDT@69541|Desulfuromonadales	28221|Deltaproteobacteria	A	Domain of unknown function (DUF3552)	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS3_k127_7266581_17	502025.Hoch_2189	8.054e-48	177.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria,2Z0X7@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS3_k127_7266581_3	1340493.JNIF01000003_gene2016	2.992e-169	549.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria	57723|Acidobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_7266581_13	937774.TEQUI_1238	4.031e-64	221.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,3T3MV@506|Alcaligenaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS3_k127_7266581_18	502025.Hoch_2191	4.037e-44	169.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,4384G@68525|delta/epsilon subdivisions,2X3ED@28221|Deltaproteobacteria,2YVPT@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS3_k127_7266581_26	945543.VIBR0546_19449	1.705e-18	93.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,1S9YH@1236|Gammaproteobacteria,1XTU9@135623|Vibrionales	135623|Vibrionales	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	GO:0006457,GO:0008150,GO:0009987	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
CMS3_k127_7266581_2	1192034.CAP_5772	1.763e-193	623.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YUFN@29|Myxococcales	28221|Deltaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CMS3_k127_7266581_22	1278073.MYSTI_05497	4.239e-30	136.0	COG0633@1|root,COG0633@2|Bacteria,1Q2HK@1224|Proteobacteria,4384E@68525|delta/epsilon subdivisions,2X3EB@28221|Deltaproteobacteria,2YVPH@29|Myxococcales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS3_k127_7266581_21	502025.Hoch_2192	1.673e-34	138.0	COG0824@1|root,COG0824@2|Bacteria,1Q2J2@1224|Proteobacteria,433TX@68525|delta/epsilon subdivisions,2X3FR@28221|Deltaproteobacteria,2YVWT@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT
CMS3_k127_7266581_14	502025.Hoch_2193	2.28e-58	220.0	COG2969@1|root,COG2969@2|Bacteria,1R39Y@1224|Proteobacteria,43DJU@68525|delta/epsilon subdivisions,2X8R3@28221|Deltaproteobacteria,2YW22@29|Myxococcales	28221|Deltaproteobacteria	S	Stringent starvation protein B	-	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
CMS3_k127_7266581_24	502025.Hoch_3286	5.786e-21	99.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42WGE@68525|delta/epsilon subdivisions,2WRF1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS3_k127_7266581_23	502025.Hoch_5120	8.516e-22	112.0	2DUA0@1|root,33PJB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7266581_0	502025.Hoch_5119	0.0	1008.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS3_k127_7266581_19	502025.Hoch_2194	7.138e-42	168.0	COG1539@1|root,COG1539@2|Bacteria,1PSII@1224|Proteobacteria,435F9@68525|delta/epsilon subdivisions,2WZST@28221|Deltaproteobacteria,2Z2P6@29|Myxococcales	28221|Deltaproteobacteria	H	Dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS3_k127_7266581_12	502025.Hoch_2195	2.052e-64	225.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,4321P@68525|delta/epsilon subdivisions,2WWQH@28221|Deltaproteobacteria,2Z2ZF@29|Myxococcales	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS3_k127_7266581_11	1408416.JNJT01000003_gene149	2.33e-65	228.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3WTN3@544448|Tenericutes	544448|Tenericutes	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS3_k127_7266581_4	502025.Hoch_2197	4.553e-144	472.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS3_k127_7266581_15	502025.Hoch_2198	7.938e-56	216.0	COG2802@1|root,COG2802@2|Bacteria,1Q90Z@1224|Proteobacteria,43426@68525|delta/epsilon subdivisions,2X4S2@28221|Deltaproteobacteria,2YVIH@29|Myxococcales	28221|Deltaproteobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
CMS3_k127_7266581_20	861299.J421_6372	2.094e-36	146.0	COG1028@1|root,COG1028@2|Bacteria,1ZTPZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_7266581_27	240015.ACP_3146	1.797e-18	100.0	COG4911@1|root,COG4911@2|Bacteria,3Y4VB@57723|Acidobacteria,2JJJA@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
CMS3_k127_7266581_16	861299.J421_3591	4.704e-52	192.0	COG1028@1|root,COG1028@2|Bacteria,1ZTNC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS3_k127_7266581_9	502025.Hoch_2200	9.956e-82	278.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
CMS3_k127_7266581_10	502025.Hoch_2201	5.84e-74	253.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2YV2V@29|Myxococcales	28221|Deltaproteobacteria	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS3_k127_7266581_6	864702.OsccyDRAFT_2627	3.618e-119	396.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria,1H6YM@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS3_k127_7266581_25	1122621.ATZA01000023_gene4206	3.605e-20	106.0	2E6H2@1|root,33149@2|Bacteria,4P13M@976|Bacteroidetes,1IW07@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7266581_1	502025.Hoch_3302	9.733e-195	621.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WMKF@28221|Deltaproteobacteria,2YWSM@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_7266581_5	502025.Hoch_3303	1.416e-132	439.0	COG4191@1|root,COG4191@2|Bacteria,1R95R@1224|Proteobacteria,42PEG@68525|delta/epsilon subdivisions,2WM8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_7289617_6	1282360.ABAC460_22605	1.686e-07	64.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2KIH3@204458|Caulobacterales	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PPC,Peptidase_M10_C
CMS3_k127_7289617_4	1144275.COCOR_00768	8.687e-17	88.0	COG0457@1|root,COG0457@2|Bacteria,1QAW9@1224|Proteobacteria,435C2@68525|delta/epsilon subdivisions,2WZPK@28221|Deltaproteobacteria,2Z2H6@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7289617_1	502025.Hoch_3876	6.131e-68	254.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria,2YXDF@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
CMS3_k127_7289617_8	1121918.ARWE01000001_gene1273	0.0008646	52.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CMS3_k127_7289617_7	7230.FBpp0167103	6.582e-05	55.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera,45XHP@7214|Drosophilidae	33208|Metazoa	T	Calcium ion binding	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
CMS3_k127_7289617_2	172045.KS04_15910	9.885e-41	173.0	COG4276@1|root,COG4276@2|Bacteria,4NQ3V@976|Bacteroidetes,1I398@117743|Flavobacteriia,34RVK@308865|Elizabethkingia	976|Bacteroidetes	S	Cell division protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7289617_0	502025.Hoch_6613	2.054e-220	701.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
CMS3_k127_7310606_5	1254432.SCE1572_06470	3.162e-17	86.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_06470|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_7310606_1	246197.MXAN_5247	1.94e-73	270.0	COG3507@1|root,COG3507@2|Bacteria,1R5F2@1224|Proteobacteria,43E6V@68525|delta/epsilon subdivisions,2X7I1@28221|Deltaproteobacteria,2YZ3Q@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS3_k127_7310606_4	1123392.AQWL01000008_gene1237	9.602e-18	98.0	COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,2VKDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,PA14
CMS3_k127_7310606_6	337191.KTR9_2025	9.64e-15	88.0	COG4409@1|root,COG4409@2|Bacteria,2GKYI@201174|Actinobacteria,4GAXV@85026|Gordoniaceae	201174|Actinobacteria	G	Domain of unknown function (DUF4185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185
CMS3_k127_7310606_0	443143.GM18_0814	9.984e-101	345.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,43TEU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_7310606_3	502025.Hoch_4028	1.613e-54	193.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2YV9P@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS3_k127_7310606_2	502025.Hoch_4027	7.993e-55	195.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2YVJG@29|Myxococcales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS3_k127_7346147_0	502025.Hoch_3372	1.225e-190	608.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,2YUNH@29|Myxococcales	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS3_k127_7346147_1	502025.Hoch_3371	1.041e-163	520.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,2YTSG@29|Myxococcales	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
CMS3_k127_7433684_2	671143.DAMO_0351	3.897e-20	96.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7433684_0	1379698.RBG1_1C00001G0113	1.502e-55	207.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7433684_1	1379698.RBG1_1C00001G0114	2.946e-35	138.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7447025_0	502025.Hoch_6047	1.041e-78	276.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	CBS,HTH_17,Na_H_Exchanger,PTS_EIIA_2
CMS3_k127_7447025_1	937777.Deipe_2180	1.382e-38	157.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
CMS3_k127_7447025_2	937777.Deipe_2178	4.881e-17	94.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,PG_binding_1,Trypsin_2
CMS3_k127_7450376_9	797114.C475_10734	1.256e-13	81.0	COG0420@1|root,arCOG00397@2157|Archaea,2XT7A@28890|Euryarchaeota,23SK4@183963|Halobacteria	183963|Halobacteria	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity	mre11	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
CMS3_k127_7450376_10	1121413.JMKT01000009_gene1819	6.042e-09	64.0	COG0515@1|root,COG0515@2|Bacteria,1PGDP@1224|Proteobacteria,43A48@68525|delta/epsilon subdivisions,2X2PI@28221|Deltaproteobacteria,2MDES@213115|Desulfovibrionales	28221|Deltaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7450376_5	861299.J421_5728	2.36e-91	323.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_7450376_1	298654.FraEuI1c_3065	2.308e-202	651.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_7450376_3	502025.Hoch_5834	1.364e-120	397.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,42TKC@68525|delta/epsilon subdivisions,2WQ16@28221|Deltaproteobacteria,2YWBJ@29|Myxococcales	28221|Deltaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
CMS3_k127_7450376_6	944480.ATUV01000001_gene1386	2.829e-70	264.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2M6ST@213113|Desulfurellales	28221|Deltaproteobacteria	O	Hsp70 protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_7450376_4	483219.LILAB_00890	1.569e-119	419.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PZJ@68525|delta/epsilon subdivisions,2WMGB@28221|Deltaproteobacteria,2YVBK@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_7450376_0	502025.Hoch_6605	4.512e-211	670.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YX9H@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase beta thumb	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
CMS3_k127_7450376_8	1030157.AFMP01000009_gene3652	7.234e-40	170.0	COG2030@1|root,COG2030@2|Bacteria,1R55D@1224|Proteobacteria,2V6YM@28211|Alphaproteobacteria,2KAS6@204457|Sphingomonadales	204457|Sphingomonadales	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_7450376_11	1298593.TOL_2993	4.265e-06	57.0	COG5608@1|root,COG5608@2|Bacteria,1N4VR@1224|Proteobacteria,1SAT2@1236|Gammaproteobacteria,1XMFE@135619|Oceanospirillales	135619|Oceanospirillales	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
CMS3_k127_7450376_7	1128421.JAGA01000002_gene1688	1.098e-44	178.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS3_k127_7450376_2	765869.BDW_07945	1.304e-127	423.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,42QEQ@68525|delta/epsilon subdivisions,2WQEB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	glp	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
CMS3_k127_745899_6	215803.DB30_7789	2.401e-93	321.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,4352D@68525|delta/epsilon subdivisions,2X2SX@28221|Deltaproteobacteria,2YWNC@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_745899_8	502025.Hoch_6657	1.306e-56	210.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_745899_1	391625.PPSIR1_00802	3.961e-176	567.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_745899_3	391625.PPSIR1_00807	1.85e-127	417.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43BP2@68525|delta/epsilon subdivisions,2WK8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	molybdopterin oxidoreductase Fe4S4 region	sfrA	-	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_10,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_745899_0	391625.PPSIR1_00812	1.31e-232	731.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_745899_2	1403819.BATR01000007_gene204	3.395e-131	426.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49,SDH_sah
CMS3_k127_745899_4	1278073.MYSTI_06076	6.138e-125	422.0	COG0013@1|root,COG0013@2|Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_745899_10	1242864.D187_001276	3.237e-44	183.0	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_745899_9	502025.Hoch_4696	9.495e-55	211.0	COG4254@1|root,COG4254@2|Bacteria,1QX4F@1224|Proteobacteria,43BX2@68525|delta/epsilon subdivisions,2X77V@28221|Deltaproteobacteria,2YX6H@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS3_k127_745899_7	502025.Hoch_4695	3.36e-64	239.0	COG4932@1|root,COG4932@2|Bacteria,1QXTV@1224|Proteobacteria,43C6B@68525|delta/epsilon subdivisions,2X7GH@28221|Deltaproteobacteria,2YXCU@29|Myxococcales	28221|Deltaproteobacteria	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_745899_5	502025.Hoch_0554	1.577e-122	405.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2WPP7@28221|Deltaproteobacteria,2YTYB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_7499028_1	391625.PPSIR1_18842	3.576e-43	164.0	COG1309@1|root,COG1309@2|Bacteria,1RCDH@1224|Proteobacteria,42VJ5@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K13770,ko:K19736	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_7499028_3	1347087.CBYO010000007_gene1136	9.341e-09	68.0	COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,4HA1I@91061|Bacilli	91061|Bacilli	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CMS3_k127_7499028_0	502025.Hoch_3517	1.149e-100	338.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
CMS3_k127_751915_12	118166.JH976537_gene833	3.001e-57	214.0	COG3781@1|root,COG3781@2|Bacteria,1G0BA@1117|Cyanobacteria,1H9QM@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG3781 membrane protein	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
CMS3_k127_751915_22	502025.Hoch_6468	8.409e-29	128.0	2A465@1|root,30SR9@2|Bacteria,1PC3P@1224|Proteobacteria,4388A@68525|delta/epsilon subdivisions,2X1C4@28221|Deltaproteobacteria,2YW6K@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_751915_14	502025.Hoch_6467	2.651e-46	191.0	2A4TP@1|root,30TF5@2|Bacteria,1PD8M@1224|Proteobacteria,435F0@68525|delta/epsilon subdivisions,2X98W@28221|Deltaproteobacteria,2Z2NT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_751915_18	1396141.BATP01000001_gene5307	8.877e-38	159.0	COG1913@1|root,COG1913@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
CMS3_k127_751915_15	349521.HCH_00733	3.812e-46	175.0	29681@1|root,2ZTI1@2|Bacteria,1RA8W@1224|Proteobacteria,1SAMV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
CMS3_k127_751915_20	215803.DB30_1719	1.236e-32	144.0	COG0739@1|root,COG0739@2|Bacteria,1PVZJ@1224|Proteobacteria,435UX@68525|delta/epsilon subdivisions,2X0AE@28221|Deltaproteobacteria,2YWKP@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_751915_29	1144275.COCOR_06877	8.459e-10	68.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_751915_4	243231.GSU2327	3.772e-120	401.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria,43UK3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_751915_10	330214.NIDE0211	1.974e-79	289.0	COG3496@1|root,COG3496@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1365)	-	-	2.1.1.79	ko:K00574,ko:K09701	-	-	-	-	ko00000,ko01000	-	-	-	DUF1365
CMS3_k127_751915_5	338966.Ppro_0127	4.924e-120	398.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,42PB7@68525|delta/epsilon subdivisions,2WKGA@28221|Deltaproteobacteria,43TGT@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS,DUF1365
CMS3_k127_751915_6	582744.Msip34_1307	4.627e-102	360.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,2VI5F@28216|Betaproteobacteria,2KMFN@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Putative methyltransferase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS3_k127_751915_16	96561.Dole_0352	9.728e-43	178.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,42R9G@68525|delta/epsilon subdivisions,2WMTN@28221|Deltaproteobacteria,2MMGZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
CMS3_k127_751915_8	391625.PPSIR1_23234	1.371e-93	332.0	COG2304@1|root,COG2304@2|Bacteria,1Q2PD@1224|Proteobacteria,438AP@68525|delta/epsilon subdivisions,2X3K0@28221|Deltaproteobacteria,2YWD7@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
CMS3_k127_751915_30	44056.XP_009039164.1	0.0001104	55.0	KOG3638@1|root,KOG3638@2759|Eukaryota	2759|Eukaryota	M	intein-mediated protein splicing	-	GO:0003002,GO:0003674,GO:0003824,GO:0004175,GO:0005102,GO:0005488,GO:0005496,GO:0005515,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007267,GO:0007275,GO:0007350,GO:0007365,GO:0007367,GO:0007389,GO:0008150,GO:0008152,GO:0008233,GO:0008289,GO:0009790,GO:0009880,GO:0009987,GO:0010467,GO:0015485,GO:0016020,GO:0016485,GO:0016540,GO:0016787,GO:0019538,GO:0023052,GO:0032501,GO:0032502,GO:0032934,GO:0035282,GO:0036094,GO:0043170,GO:0043178,GO:0044238,GO:0044464,GO:0048856,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901564	-	ko:K06224,ko:K11990,ko:K16669	ko04340,ko04341,ko04391,ko04392,map04340,map04341,map04391,map04392	M00678	-	-	ko00000,ko00001,ko00002,ko00536,ko01002,ko04516	-	-	-	Ground-like,Hint,Kelch_4
CMS3_k127_751915_9	1121033.AUCF01000020_gene730	2.799e-89	303.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5HA@28211|Alphaproteobacteria,2JRUX@204441|Rhodospirillales	204441|Rhodospirillales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_751915_24	555500.I215_12733	7.403e-20	104.0	COG4632@1|root,COG4632@2|Bacteria,4NQZB@976|Bacteroidetes,1IIJ0@117743|Flavobacteriia	976|Bacteroidetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
CMS3_k127_751915_17	404589.Anae109_0883	2.087e-38	151.0	COG5516@1|root,COG5516@2|Bacteria,1N7M4@1224|Proteobacteria	1224|Proteobacteria	S	Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
CMS3_k127_751915_19	1123073.KB899241_gene2115	3.705e-37	143.0	COG0346@1|root,COG0346@2|Bacteria,1N3K0@1224|Proteobacteria,1SBM8@1236|Gammaproteobacteria,1X6WJ@135614|Xanthomonadales	135614|Xanthomonadales	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_751915_21	68170.KL590490_gene1267	1.021e-31	141.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	exbB2	-	-	ko:K03561,ko:K12287	-	-	-	-	ko00000,ko02000,ko02044	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
CMS3_k127_751915_0	502025.Hoch_4902	6.015e-164	537.0	COG1073@1|root,COG1073@2|Bacteria,1NKA5@1224|Proteobacteria,438I9@68525|delta/epsilon subdivisions,2X9SF@28221|Deltaproteobacteria,2YX1V@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_751915_1	502025.Hoch_5306	1.018e-151	506.0	COG2208@1|root,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2YVEB@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
CMS3_k127_751915_2	1242864.D187_001086	1.134e-136	455.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria	1224|Proteobacteria	M	Spore Coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_751915_13	502025.Hoch_4039	1.929e-53	207.0	2E00X@1|root,32VQ9@2|Bacteria,1NZY3@1224|Proteobacteria,431M9@68525|delta/epsilon subdivisions,2WWPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_751915_11	502025.Hoch_4040	1.482e-61	220.0	COG0569@1|root,COG0569@2|Bacteria,1R7KM@1224|Proteobacteria,42PJH@68525|delta/epsilon subdivisions,2WMZT@28221|Deltaproteobacteria,2YVX6@29|Myxococcales	28221|Deltaproteobacteria	C	TrkA-C domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS3_k127_751915_3	502025.Hoch_4041	2.675e-123	419.0	COG0168@1|root,COG0168@2|Bacteria,1N412@1224|Proteobacteria,42MBI@68525|delta/epsilon subdivisions,2WIZ9@28221|Deltaproteobacteria,2YURM@29|Myxococcales	28221|Deltaproteobacteria	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS3_k127_751915_7	502025.Hoch_0884	1.019e-93	334.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
CMS3_k127_751915_26	446462.Amir_3028	2.449e-11	76.0	COG1044@1|root,COG1044@2|Bacteria,2IAF7@201174|Actinobacteria,4E8AS@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
CMS3_k127_751915_25	502025.Hoch_2677	2.626e-15	89.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_751915_28	525368.HMPREF0591_6063	2.012e-10	70.0	2E9A0@1|root,333I1@2|Bacteria,2HSBR@201174|Actinobacteria,233C7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4333
CMS3_k127_7525821_2	502025.Hoch_6887	1.041e-73	251.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_7525821_1	502025.Hoch_6886	1.329e-86	294.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2Z0N2@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS3_k127_7525821_0	502025.Hoch_6885	1.697e-88	306.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,42T7F@68525|delta/epsilon subdivisions,2WP8W@28221|Deltaproteobacteria,2YWFQ@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_7616282_6	1192034.CAP_2556	6.92e-20	96.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
CMS3_k127_7616282_9	269796.Rru_A0691	3.209e-10	68.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1R6YN@1224|Proteobacteria,2U3FG@28211|Alphaproteobacteria,2JQBD@204441|Rhodospirillales	204441|Rhodospirillales	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS3_k127_7616282_7	502025.Hoch_1830	8.951e-19	98.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_7616282_11	1254432.SCE1572_43550	7.672e-05	54.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
CMS3_k127_7616282_0	502025.Hoch_1460	3.46e-133	460.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,4383V@68525|delta/epsilon subdivisions,2X0HP@28221|Deltaproteobacteria,2YVM9@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_7616282_10	96561.Dole_1273	2.886e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1RKQQ@1224|Proteobacteria,42T9T@68525|delta/epsilon subdivisions,2WPQ0@28221|Deltaproteobacteria,2MN67@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_16,TPR_2,TPR_8
CMS3_k127_7616282_8	1254432.SCE1572_00325	4.003e-18	100.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2YZYM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
CMS3_k127_7616282_4	448385.sce1847	2.068e-36	159.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
CMS3_k127_7616282_2	1121935.AQXX01000059_gene1976	9.312e-74	281.0	COG0300@1|root,COG0300@2|Bacteria,1QUVN@1224|Proteobacteria,1T22I@1236|Gammaproteobacteria,1XJDB@135619|Oceanospirillales	135619|Oceanospirillales	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_7616282_3	502025.Hoch_6108	1.749e-38	156.0	COG0782@1|root,COG0782@2|Bacteria,1MZNI@1224|Proteobacteria,42VKP@68525|delta/epsilon subdivisions,2WSC9@28221|Deltaproteobacteria,2Z1RW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcription elongation factor, GreA/GreB, C-term	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
CMS3_k127_7616282_1	883156.HMPREF9282_00809	2.532e-113	382.0	COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4H1ZC@909932|Negativicutes	909932|Negativicutes	P	transporter	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
CMS3_k127_7616282_5	1151061.CAJY01000017_gene356	1.338e-27	117.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	ADP_ribosyl_GH,Lpp-LpqN,Pkinase
CMS3_k127_810539_4	744979.R2A130_1777	2.735e-90	301.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_810539_5	929712.KI912613_gene3309	1.565e-82	287.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria,4CPPS@84995|Rubrobacteria	84995|Rubrobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
CMS3_k127_810539_1	391625.PPSIR1_28641	1.875e-174	553.0	COG0714@1|root,COG0714@2|Bacteria,1QAW5@1224|Proteobacteria,42PY2@68525|delta/epsilon subdivisions,2WKGF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
CMS3_k127_810539_8	391625.PPSIR1_07178	5.735e-53	197.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_810539_6	1206729.BAFZ01000050_gene5395	6.303e-78	278.0	COG1020@1|root,COG1020@2|Bacteria,2GPHZ@201174|Actinobacteria,4FURZ@85025|Nocardiaceae	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_810539_2	502025.Hoch_5238	6.318e-138	445.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YU8R@29|Myxococcales	28221|Deltaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_810539_3	502025.Hoch_5237	1.163e-97	323.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_827664_2	404589.Anae109_4276	2.698e-10	65.0	COG3213@1|root,COG3213@2|Bacteria,1Q61U@1224|Proteobacteria,4328M@68525|delta/epsilon subdivisions,2WXFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NnrS protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
CMS3_k127_827664_3	118166.JH976538_gene4978	2.071e-05	56.0	COG5279@1|root,COG5279@2|Bacteria,1G2DZ@1117|Cyanobacteria,1HA0U@1150|Oscillatoriales	1117|Cyanobacteria	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_827664_1	522772.Dacet_1674	1.858e-28	125.0	COG1763@1|root,COG1763@2|Bacteria,2GFTP@200930|Deferribacteres	200930|Deferribacteres	H	Molybdopterin guanine dinucleotide synthesis protein B	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
CMS3_k127_827664_5	243231.GSU1945	0.0007093	49.0	COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,1Q4PP@1224|Proteobacteria,42YRG@68525|delta/epsilon subdivisions,2WUJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3
CMS3_k127_827664_4	247490.KSU1_D0439	2.215e-05	55.0	COG0823@1|root,COG0823@2|Bacteria,2J1JX@203682|Planctomycetes	203682|Planctomycetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_850929_0	290397.Adeh_1015	4.068e-82	281.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,42NVI@68525|delta/epsilon subdivisions,2WJTD@28221|Deltaproteobacteria,2YTYS@29|Myxococcales	28221|Deltaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_850929_2	502025.Hoch_3172	4.878e-39	158.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,42QGY@68525|delta/epsilon subdivisions,2WKHR@28221|Deltaproteobacteria,2Z0V8@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_850929_5	502025.Hoch_1818	8.985e-06	56.0	COG0457@1|root,COG0457@2|Bacteria,1R0CA@1224|Proteobacteria,43EDM@68525|delta/epsilon subdivisions,2X82F@28221|Deltaproteobacteria,2Z26J@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_850929_3	483219.LILAB_16385	3.907e-35	145.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42VZ4@68525|delta/epsilon subdivisions,2WRDI@28221|Deltaproteobacteria,2YW4T@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_850929_4	391625.PPSIR1_18342	4.984e-22	108.0	2DSXQ@1|root,33HVC@2|Bacteria,1N9KU@1224|Proteobacteria,43CND@68525|delta/epsilon subdivisions,2X7VP@28221|Deltaproteobacteria,2Z3IK@29|Myxococcales	28221|Deltaproteobacteria	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1
CMS3_k127_850929_1	502025.Hoch_1923	8.119e-50	199.0	COG0204@1|root,COG0204@2|Bacteria,1PZS9@1224|Proteobacteria,434JR@68525|delta/epsilon subdivisions,2WYX1@28221|Deltaproteobacteria,2Z0U7@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_851284_2	1120936.KB907208_gene678	1.476e-32	134.0	COG2730@1|root,COG2730@2|Bacteria,2HQAQ@201174|Actinobacteria,4EJKM@85012|Streptosporangiales	201174|Actinobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.123	ko:K05991	-	-	-	-	ko00000,ko01000	-	GH5	-	Cellulase
CMS3_k127_851284_1	1380390.JIAT01000009_gene1680	1.482e-84	288.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria,4CU4M@84995|Rubrobacteria	84995|Rubrobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_851284_0	644282.Deba_0630	8.898e-102	358.0	COG0745@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg,sCache_2
CMS3_k127_865983_0	292415.Tbd_2266	4.271e-267	844.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_865983_2	243924.LT42_05455	2.153e-37	163.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1S8ZG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	cueR	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind
CMS3_k127_865983_5	1110502.TMO_1754	1.486e-10	69.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,2UJAW@28211|Alphaproteobacteria,2JUIS@204441|Rhodospirillales	204441|Rhodospirillales	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
CMS3_k127_865983_3	1254432.SCE1572_45175	3.913e-18	95.0	2AIUN@1|root,319BU@2|Bacteria,1Q29W@1224|Proteobacteria,437WR@68525|delta/epsilon subdivisions,2X36D@28221|Deltaproteobacteria,2YUHX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_865983_1	502025.Hoch_6474	1.651e-149	481.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,42PNZ@68525|delta/epsilon subdivisions,2WM13@28221|Deltaproteobacteria,2YUDU@29|Myxococcales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS3_k127_865983_4	502025.Hoch_6473	3.796e-16	79.0	COG3255@1|root,COG3255@2|Bacteria,1PWYZ@1224|Proteobacteria,432A7@68525|delta/epsilon subdivisions,2WXR1@28221|Deltaproteobacteria,2YW4M@29|Myxococcales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_871639_9	443143.GM18_1366	1.858e-51	190.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS3_k127_871639_12	502025.Hoch_2512	9.978e-28	124.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_871639_2	502025.Hoch_1843	4.387e-123	422.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,42V1G@68525|delta/epsilon subdivisions,2WRCZ@28221|Deltaproteobacteria,2YWCA@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_871639_3	502025.Hoch_0313	5.417e-121	406.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42UMR@68525|delta/epsilon subdivisions,2WQ71@28221|Deltaproteobacteria,2YVN1@29|Myxococcales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS3_k127_871639_11	502025.Hoch_6451	3.777e-29	136.0	COG0457@1|root,COG0457@2|Bacteria,1QASZ@1224|Proteobacteria,435A3@68525|delta/epsilon subdivisions,2WZM6@28221|Deltaproteobacteria,2Z2D1@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_871639_4	502025.Hoch_6452	3.432e-101	351.0	COG0515@1|root,COG0515@2|Bacteria	502025.Hoch_6452|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_871639_13	502025.Hoch_6001	6.017e-27	124.0	COG1534@1|root,COG1534@2|Bacteria,1Q1J9@1224|Proteobacteria,42WJ8@68525|delta/epsilon subdivisions,2WRWD@28221|Deltaproteobacteria,2Z332@29|Myxococcales	28221|Deltaproteobacteria	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
CMS3_k127_871639_8	460265.Mnod_6880	3.799e-72	255.0	COG3662@1|root,COG3662@2|Bacteria,1R50Q@1224|Proteobacteria,2TSG5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
CMS3_k127_871639_1	269799.Gmet_1089	8.137e-128	427.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2WMH2@28221|Deltaproteobacteria,43TI5@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS3_k127_871639_10	502025.Hoch_3797	2.837e-47	175.0	COG2036@1|root,COG2036@2|Bacteria,1N3S6@1224|Proteobacteria,42UYX@68525|delta/epsilon subdivisions,2WQE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_871639_6	502025.Hoch_2723	3.412e-82	290.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2Z0NX@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
CMS3_k127_871639_0	246197.MXAN_7310	3.579e-133	428.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,42YTV@68525|delta/epsilon subdivisions,2WTY1@28221|Deltaproteobacteria,2YYUF@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
CMS3_k127_871639_7	502025.Hoch_0367	6.86e-78	295.0	COG0500@1|root,COG2226@2|Bacteria,1NDFZ@1224|Proteobacteria,42R89@68525|delta/epsilon subdivisions,2X5PC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	UbiE COQ5 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_871639_15	246197.MXAN_5315	9.551e-06	59.0	COG3794@1|root,COG3794@2|Bacteria,1Q2EH@1224|Proteobacteria,43807@68525|delta/epsilon subdivisions,2X3A8@28221|Deltaproteobacteria,2YV38@29|Myxococcales	28221|Deltaproteobacteria	C	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_871639_5	243233.MCA1365	5.587e-97	327.0	COG0727@1|root,COG0727@2|Bacteria,1N37X@1224|Proteobacteria	1224|Proteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS3_k127_871639_14	246197.MXAN_6216	3.506e-24	115.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS3_k127_88144_3	502025.Hoch_3520	4.23e-146	474.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWC8@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_88144_5	926562.Oweho_3326	2.597e-120	406.0	COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	macB_3	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_88144_6	502025.Hoch_3518	1.932e-114	381.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2Z1Y7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_88144_24	765420.OSCT_1025	5.454e-21	103.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,3772Y@32061|Chloroflexia	32061|Chloroflexia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS3_k127_88144_22	1242864.D187_005314	1.039e-30	128.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,1P49S@1224|Proteobacteria,4350R@68525|delta/epsilon subdivisions,2WZBJ@28221|Deltaproteobacteria,2Z1SD@29|Myxococcales	28221|Deltaproteobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_88144_11	1173028.ANKO01000129_gene1998	2.277e-52	209.0	COG1785@1|root,COG1785@2|Bacteria,1G4BJ@1117|Cyanobacteria	1117|Cyanobacteria	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS3_k127_88144_20	1206731.BAGB01000061_gene3326	2.593e-34	143.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4G0P0@85025|Nocardiaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_88144_9	1144275.COCOR_02243	1.267e-98	344.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CMS3_k127_88144_13	502025.Hoch_5007	6.438e-42	171.0	COG0589@1|root,COG0589@2|Bacteria,1NN89@1224|Proteobacteria,434TG@68525|delta/epsilon subdivisions,2WZ4G@28221|Deltaproteobacteria,2Z1B6@29|Myxococcales	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_88144_15	1254432.SCE1572_35725	4.091e-38	159.0	COG0529@1|root,COG0529@2|Bacteria,1QTVY@1224|Proteobacteria,434UM@68525|delta/epsilon subdivisions,2WZ5M@28221|Deltaproteobacteria,2Z1DN@29|Myxococcales	28221|Deltaproteobacteria	P	Adenylylsulfate kinase	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS3_k127_88144_4	1254432.SCE1572_35720	4.989e-136	442.0	COG3173@1|root,COG3173@2|Bacteria,1R8W5@1224|Proteobacteria,42PZM@68525|delta/epsilon subdivisions,2WM50@28221|Deltaproteobacteria,2YXAW@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_88144_27	469383.Cwoe_1887	5.388e-15	85.0	COG0517@1|root,COG0517@2|Bacteria,2HPZ3@201174|Actinobacteria,4CREF@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_88144_21	502025.Hoch_5116	3.951e-34	138.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_88144_14	215803.DB30_5108	1.138e-40	154.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2Z0B0@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_88144_12	502025.Hoch_0149	2.447e-46	172.0	COG1186@1|root,COG1186@2|Bacteria,1ND5C@1224|Proteobacteria,430VS@68525|delta/epsilon subdivisions,2WW3U@28221|Deltaproteobacteria,2Z2GT@29|Myxococcales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS3_k127_88144_0	330214.NIDE2929	1.191e-242	764.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	2|Bacteria	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	3.4.21.53	ko:K03798,ko:K04076,ko:K13525,ko:K17681	ko04141,ko05134,map04141,map05134	M00400,M00403,M00742	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03019,ko03029,ko03110,ko04131,ko04147	3.A.16.1	-	-	AAA,FtsH_ext,Peptidase_M41
CMS3_k127_88144_23	1201288.M900_1863	1.032e-29	135.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
CMS3_k127_88144_26	283942.IL0161	1.882e-19	102.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MVJE@1224|Proteobacteria,1RQ2M@1236|Gammaproteobacteria,2QF1S@267893|Idiomarinaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,PA,Peptidase_S8
CMS3_k127_88144_18	926564.KI911678_gene5264	5.842e-35	143.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2HQIW@201174|Actinobacteria,4F5H7@85017|Promicromonosporaceae	2|Bacteria	O	Subtilase family	bpr	GO:0005575,GO:0005576	3.2.1.4	ko:K01179,ko:K13276	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Malectin,PKD,Peptidase_M6,Peptidase_S8
CMS3_k127_88144_16	861299.J421_1866	3.51e-37	162.0	28P9J@1|root,2ZC30@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_88144_1	391625.PPSIR1_37129	3.034e-241	756.0	COG0069@1|root,COG4638@1|root,COG0069@2|Bacteria,COG4638@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJJR@28221|Deltaproteobacteria,2Z2X8@29|Myxococcales	28221|Deltaproteobacteria	E	Conserved region in glutamate synthase	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Fer4_7,Fer4_9,GXGXG,Glu_syn_central,Glu_synthase
CMS3_k127_88144_25	1192034.CAP_5110	2.916e-20	96.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_88144_7	1123261.AXDW01000002_gene1665	4.849e-104	361.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1X42V@135614|Xanthomonadales	135614|Xanthomonadales	H	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS3_k127_88144_8	502025.Hoch_6056	5.538e-102	346.0	COG0515@1|root,COG0515@2|Bacteria,1Q31E@1224|Proteobacteria,438RJ@68525|delta/epsilon subdivisions,2X991@28221|Deltaproteobacteria,2YXKM@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_88144_19	1254432.SCE1572_16540	1.31e-34	154.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_16540|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_88144_10	246197.MXAN_0755	1.139e-58	223.0	COG0515@1|root,COG0515@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pkn9	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_88144_17	870187.Thini_0126	6.032e-36	158.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,46162@72273|Thiotrichales	72273|Thiotrichales	P	arsenate reductase	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS3_k127_88144_2	886293.Sinac_1156	2.266e-231	745.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_903260_5	391625.PPSIR1_03323	5.324e-15	78.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2X5YA@28221|Deltaproteobacteria,2YUMQ@29|Myxococcales	28221|Deltaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS3_k127_903260_7	391625.PPSIR1_21539	5.453e-10	64.0	COG2378@1|root,COG2378@2|Bacteria,1Q3JM@1224|Proteobacteria,439CG@68525|delta/epsilon subdivisions,2X4KT@28221|Deltaproteobacteria,2YZ7T@29|Myxococcales	28221|Deltaproteobacteria	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS3_k127_903260_4	404589.Anae109_4096	1.386e-25	121.0	COG1538@1|root,COG1538@2|Bacteria,1PKT6@1224|Proteobacteria,4354V@68525|delta/epsilon subdivisions,2X95H@28221|Deltaproteobacteria,2Z21V@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
CMS3_k127_903260_1	404589.Anae109_4095	8.919e-81	296.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,42SFA@68525|delta/epsilon subdivisions,2WUV2@28221|Deltaproteobacteria,2YVKJ@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS3_k127_903260_0	404589.Anae109_4094	0.0	1130.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS3_k127_903260_6	521393.JH806633_gene1771	3.546e-13	73.0	COG0640@1|root,COG0640@2|Bacteria,2IMSD@201174|Actinobacteria,4D5UX@85005|Actinomycetales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	smtB	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010043,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0044212,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS3_k127_903260_2	1489678.RDMS_12985	1.312e-79	276.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	zitB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	iNRG857_1313.NRG857_03325,iPC815.YPO1129	Cation_efflux,ZT_dimer
CMS3_k127_903260_3	502025.Hoch_2491	2.633e-54	214.0	COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUXH@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
CMS3_k127_914148_3	246194.CHY_1999	6.585e-32	137.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,42EY5@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Conserved carboxylase region	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
CMS3_k127_914148_1	502025.Hoch_0255	2.42e-60	212.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria,2YVRN@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS3_k127_914148_2	502025.Hoch_0254	1.804e-39	149.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,2YVP4@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_914148_0	502025.Hoch_0253	8.27e-143	468.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria,2YV4V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CMS3_k127_934418_2	279714.FuraDRAFT_3206	1.287e-151	489.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CMS3_k127_934418_1	391625.PPSIR1_41589	1.769e-152	498.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_934418_14	593117.TGAM_1390	1.733e-06	59.0	COG4945@1|root,arCOG03264@1|root,arCOG01310@2157|Archaea,arCOG03264@2157|Archaea,arCOG03771@2157|Archaea,2XSTV@28890|Euryarchaeota,245KU@183968|Thermococci	183968|Thermococci	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C,PEGA
CMS3_k127_934418_11	1254432.SCE1572_07145	9.126e-32	133.0	COG3428@1|root,COG3428@2|Bacteria,1Q645@1224|Proteobacteria,435EH@68525|delta/epsilon subdivisions,2WZS7@28221|Deltaproteobacteria,2Z2MQ@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CMS3_k127_934418_12	502025.Hoch_3877	2.66e-29	132.0	COG0457@1|root,COG0457@2|Bacteria,1QAW9@1224|Proteobacteria,435C2@68525|delta/epsilon subdivisions,2WZPK@28221|Deltaproteobacteria,2Z2H6@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_934418_4	502025.Hoch_3876	3.776e-119	403.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria,2YXDF@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
CMS3_k127_934418_15	1380386.JIAW01000021_gene2113	2.136e-05	57.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,23EVE@1762|Mycobacteriaceae	201174|Actinobacteria	S	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,PD40,PQQ_2
CMS3_k127_934418_0	502025.Hoch_6321	9.28e-171	560.0	COG1629@1|root,COG4771@2|Bacteria,1QZT6@1224|Proteobacteria,43CN5@68525|delta/epsilon subdivisions,2X7VE@28221|Deltaproteobacteria,2Z2JA@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_934418_6	502025.Hoch_3875	1.818e-85	291.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,42NZ8@68525|delta/epsilon subdivisions,2WK0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
CMS3_k127_934418_8	502025.Hoch_3874	5.614e-54	216.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_934418_10	502025.Hoch_3873	3.552e-40	173.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_934418_7	1192034.CAP_1552	1.459e-65	256.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD
CMS3_k127_934418_3	502025.Hoch_0400	1.264e-145	475.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Sigma54_activat
CMS3_k127_934418_9	502025.Hoch_0401	9.973e-51	186.0	2AS5D@1|root,32BXX@2|Bacteria,1QADV@1224|Proteobacteria,4350N@68525|delta/epsilon subdivisions,2X93Y@28221|Deltaproteobacteria,2Z1S2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_934418_5	502025.Hoch_0402	8.041e-93	322.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX63@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
CMS3_k127_950081_13	1229780.BN381_50061	1.21e-66	239.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,3UWHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_950081_20	391625.PPSIR1_26493	3.689e-51	204.0	COG0625@1|root,COG0625@2|Bacteria,1PD8F@1224|Proteobacteria,435EY@68525|delta/epsilon subdivisions,2WZSI@28221|Deltaproteobacteria,2Z2NR@29|Myxococcales	28221|Deltaproteobacteria	H	glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3,GST_N
CMS3_k127_950081_26	1305836.AXVE01000012_gene88	1.55e-34	141.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	yueD	-	-	-	-	-	-	-	-	-	-	-	DUF4336,adh_short,adh_short_C2
CMS3_k127_950081_14	391625.PPSIR1_06381	4.629e-65	243.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pknB	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_950081_7	1297742.A176_03049	5.835e-87	302.0	2AITU@1|root,319AW@2|Bacteria,1Q27H@1224|Proteobacteria,437U3@68525|delta/epsilon subdivisions,2X33P@28221|Deltaproteobacteria,2YU31@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_950081_0	886293.Sinac_1156	7.175e-317	1010.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,2J2QS@203682|Planctomycetes	203682|Planctomycetes	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_950081_18	398767.Glov_3614	3.084e-52	196.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WK8V@28221|Deltaproteobacteria,43VZ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
CMS3_k127_950081_33	1283299.AUKG01000002_gene5121	6.86e-10	66.0	2DS52@1|root,33EJF@2|Bacteria,2H1N9@201174|Actinobacteria,4CST5@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_950081_2	1254432.SCE1572_00985	3.513e-234	760.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
CMS3_k127_950081_4	247639.MGP2080_08841	1.785e-126	417.0	COG2271@1|root,COG2271@2|Bacteria,1MXUC@1224|Proteobacteria,1RRF8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_950081_30	1123277.KB893172_gene717	1.01e-15	90.0	COG2010@1|root,COG2010@2|Bacteria,4PPRH@976|Bacteroidetes,47YQV@768503|Cytophagia	976|Bacteroidetes	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_950081_9	1333998.M2A_0505	4.208e-85	289.0	COG2102@1|root,COG2102@2|Bacteria,1MUU2@1224|Proteobacteria,2U3M8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
CMS3_k127_950081_23	945713.IALB_2304	1.611e-43	166.0	2CBKC@1|root,32RTJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_950081_17	396588.Tgr7_0249	2.929e-52	201.0	COG3128@1|root,COG3128@2|Bacteria,1MVVI@1224|Proteobacteria	1224|Proteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
CMS3_k127_950081_24	521011.Mpal_1345	1.686e-42	171.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
CMS3_k127_950081_8	246197.MXAN_4557	1.324e-86	313.0	COG0515@1|root,COG0515@2|Bacteria	246197.MXAN_4557|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_950081_21	502025.Hoch_6343	2.263e-50	193.0	COG2204@1|root,COG2204@2|Bacteria,1R0E3@1224|Proteobacteria,43CWJ@68525|delta/epsilon subdivisions,2WSIM@28221|Deltaproteobacteria,2YW6V@29|Myxococcales	2|Bacteria	T	response regulator	cpaE	-	2.7.13.3	ko:K02282,ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022,ko02035,ko02044	-	-	-	HATPase_c,HTH_18,HisKA,Response_reg
CMS3_k127_950081_36	1121406.JAEX01000016_gene1884	3.822e-05	57.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,2MGAZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
CMS3_k127_950081_22	1297742.A176_02836	2.552e-44	181.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,2Z01G@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
CMS3_k127_950081_15	1242864.D187_007102	9.274e-62	239.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_950081_29	1177594.MIC448_20006	2.132e-16	89.0	COG0737@1|root,COG2374@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,2GKC3@201174|Actinobacteria,4FK4R@85023|Microbacteriaceae	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Big_3_5,Exo_endo_phos,LTD,Metallophos
CMS3_k127_950081_3	215803.DB30_4777	4.308e-152	494.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42UHA@68525|delta/epsilon subdivisions,2WQA0@28221|Deltaproteobacteria,2YUHZ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS3_k127_950081_11	472759.Nhal_0303	3.235e-73	250.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,1S1HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_950081_5	1144275.COCOR_04205	5.879e-111	377.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YY4Y@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70,PilZ
CMS3_k127_950081_32	1379698.RBG1_1C00001G0231	8.974e-11	75.0	COG1413@1|root,COG1413@2|Bacteria,2NRMK@2323|unclassified Bacteria	2|Bacteria	C	HEAT repeats	CP_0755	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Response_reg
CMS3_k127_950081_31	1007103.AFHW01000103_gene5316	1.509e-11	77.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,4HBV6@91061|Bacilli,26RX7@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	cnpD3	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
CMS3_k127_950081_27	404589.Anae109_1701	1.445e-33	148.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,42VV6@68525|delta/epsilon subdivisions,2WS0G@28221|Deltaproteobacteria,2Z2P8@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
CMS3_k127_950081_6	991905.SL003B_3469	7.675e-90	314.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,4BQ02@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS3_k127_950081_16	1173028.ANKO01000116_gene5719	2.554e-53	199.0	COG2114@1|root,COG2114@2|Bacteria,1G6D6@1117|Cyanobacteria,1HB2S@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_950081_35	1254432.SCE1572_11855	1.542e-06	60.0	COG3391@1|root,COG3391@2|Bacteria,1Q2JN@1224|Proteobacteria,4386H@68525|delta/epsilon subdivisions,2X9ZH@28221|Deltaproteobacteria,2YVZH@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Stig1
CMS3_k127_950081_1	502025.Hoch_4267	1.338e-301	933.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2YU94@29|Myxococcales	28221|Deltaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_950081_25	448385.sce1365	2.77e-40	165.0	COG1520@1|root,COG1520@2|Bacteria,1Q2JS@1224|Proteobacteria,4386K@68525|delta/epsilon subdivisions,2X3GH@28221|Deltaproteobacteria,2YVZV@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_950081_34	1297742.A176_07047	3.164e-09	69.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS3_k127_950081_12	448385.sce2856	2.261e-67	252.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2WNTB@28221|Deltaproteobacteria,2Z0SP@29|Myxococcales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
CMS3_k127_950081_19	1452718.JBOY01000094_gene2906	1.718e-51	190.0	COG3791@1|root,COG3791@2|Bacteria,1RD31@1224|Proteobacteria,1S42C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alanine acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_950081_10	404589.Anae109_3852	4.309e-77	274.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS3_k127_96643_8	502025.Hoch_1957	3.484e-86	288.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS3_k127_96643_6	502025.Hoch_5292	1.286e-109	375.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWWJ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS3_k127_96643_0	502025.Hoch_1995	1.431e-220	692.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2YTUP@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_96643_5	502025.Hoch_0359	2.618e-126	413.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2WN8T@28221|Deltaproteobacteria,2Z308@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS3_k127_96643_9	404589.Anae109_3887	4.463e-80	276.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_96643_15	1121396.KB893051_gene3439	1.569e-11	75.0	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MHXZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_96643_7	1379698.RBG1_1C00001G1237	8.295e-102	352.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	zraR	GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_96643_14	290397.Adeh_3776	3.403e-37	152.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2YVR5@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS3_k127_96643_2	502025.Hoch_5215	1.559e-185	602.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS3_k127_96643_3	502025.Hoch_5214	2.646e-170	561.0	COG0206@1|root,COG3170@1|root,COG0206@2|Bacteria,COG3170@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2YTTW@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS3_k127_96643_10	502025.Hoch_6855	1.668e-78	265.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,42PR0@68525|delta/epsilon subdivisions,2X1Z5@28221|Deltaproteobacteria,2Z0GI@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep
CMS3_k127_96643_16	1297742.A176_07080	7.494e-06	59.0	COG4775@1|root,COG4775@2|Bacteria,1QUE3@1224|Proteobacteria,430IG@68525|delta/epsilon subdivisions,2WVP9@28221|Deltaproteobacteria,2YVI0@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_96643_4	502025.Hoch_6856	2.411e-134	432.0	COG0863@1|root,COG4123@1|root,COG0863@2|Bacteria,COG4123@2|Bacteria,1NXST@1224|Proteobacteria,43A23@68525|delta/epsilon subdivisions,2X2KZ@28221|Deltaproteobacteria,2Z1WP@29|Myxococcales	28221|Deltaproteobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_96643_13	1333998.M2A_1992	3.166e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,1NB4W@1224|Proteobacteria,2UIGM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_96643_12	1192034.CAP_4410	6.884e-41	159.0	COG5031@1|root,COG5031@2|Bacteria,1NF8V@1224|Proteobacteria,434IK@68525|delta/epsilon subdivisions,2X8WT@28221|Deltaproteobacteria,2Z0RP@29|Myxococcales	28221|Deltaproteobacteria	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	-	-	-	-	-	-	-	-	-	Coq4
CMS3_k127_96643_1	404589.Anae109_3440	1.022e-185	602.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YUNQ@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_974084_12	1280954.HPO_01702	7.83e-21	93.0	COG0454@1|root,COG0456@2|Bacteria,1RHB3@1224|Proteobacteria,2UD6D@28211|Alphaproteobacteria,43YQS@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	MA20_22190	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_974084_6	391625.PPSIR1_20849	3.12e-64	231.0	COG0121@1|root,COG0121@2|Bacteria,1QJ12@1224|Proteobacteria,43E2Q@68525|delta/epsilon subdivisions,2X96J@28221|Deltaproteobacteria,2Z280@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoinositide phospholipase C, Ca2+-dependent	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1
CMS3_k127_974084_0	1254432.SCE1572_51745	1.986e-211	701.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1Q4QW@1224|Proteobacteria,4388X@68525|delta/epsilon subdivisions,2X3II@28221|Deltaproteobacteria,2YW8D@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS3_k127_974084_13	941449.dsx2_2749	1.39e-15	81.0	COG1246@1|root,COG1246@2|Bacteria,1R0RF@1224|Proteobacteria,43D0Y@68525|delta/epsilon subdivisions,2X88U@28221|Deltaproteobacteria,2MHDF@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM C_GCAxxG_C_C family protein	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
CMS3_k127_974084_5	378806.STAUR_6882	3.153e-76	267.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
CMS3_k127_974084_1	1415779.JOMH01000001_gene3235	9.626e-182	590.0	COG0477@1|root,COG2814@2|Bacteria,1R2KY@1224|Proteobacteria,1RZ6A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Pfam Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_974084_9	926561.KB900618_gene414	1.578e-35	144.0	COG1670@1|root,COG1670@2|Bacteria,1V36S@1239|Firmicutes,24FW8@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_974084_3	502025.Hoch_6393	1.138e-109	372.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_974084_10	502025.Hoch_3438	2.461e-31	128.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WT56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_974084_2	886293.Sinac_0398	3.285e-111	370.0	COG3239@1|root,COG3239@2|Bacteria,2J2N5@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_974084_4	502025.Hoch_5811	1.734e-103	357.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TR@1224|Proteobacteria,437GP@68525|delta/epsilon subdivisions,2X2PH@28221|Deltaproteobacteria,2YX5V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_974084_15	1297742.A176_00262	1.508e-10	76.0	COG1470@1|root,COG2885@1|root,COG4719@1|root,COG1470@2|Bacteria,COG2885@2|Bacteria,COG4719@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
CMS3_k127_974084_16	1192034.CAP_3810	0.0009793	52.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1,RCC1_2
CMS3_k127_974084_11	10224.XP_002738893.1	7.732e-28	131.0	2D060@1|root,2SCYI@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_974084_8	7739.XP_002597416.1	1.522e-43	182.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,48CY1@7711|Chordata	33208|Metazoa	T	EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_3,EGF_CA,Lectin_C,TIL
CMS3_k127_974084_7	502025.Hoch_4959	6.803e-61	235.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4399Y@68525|delta/epsilon subdivisions,2X4HE@28221|Deltaproteobacteria,2YZ0V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase; unclassified specificity.	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_974400_0	502025.Hoch_4570	3.398e-59	216.0	2AN96@1|root,31D78@2|Bacteria,1QAAX@1224|Proteobacteria,434Y2@68525|delta/epsilon subdivisions,2WZ8X@28221|Deltaproteobacteria,2Z1KT@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS3_k127_980906_7	502025.Hoch_3320	7.307e-45	164.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_980906_8	502025.Hoch_1864	5.051e-39	153.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_980906_6	56110.Oscil6304_2231	6.089e-79	276.0	COG2513@1|root,COG2513@2|Bacteria,1G300@1117|Cyanobacteria,1H9AY@1150|Oscillatoriales	1117|Cyanobacteria	G	COG2513 PEP phosphonomutase and related enzymes	-	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
CMS3_k127_980906_0	502025.Hoch_4217	3.966e-308	961.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2YXS2@29|Myxococcales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
CMS3_k127_980906_1	502025.Hoch_6332	1.094e-225	722.0	COG0515@1|root,COG3642@1|root,COG0515@2|Bacteria,COG3642@2|Bacteria,1MV1P@1224|Proteobacteria,434IZ@68525|delta/epsilon subdivisions,2X8WW@28221|Deltaproteobacteria,2Z0SD@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_19
CMS3_k127_980906_5	502025.Hoch_6331	1.254e-113	377.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria,2YUVV@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
CMS3_k127_980906_3	502025.Hoch_6330	1.536e-117	403.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
CMS3_k127_980906_9	502025.Hoch_0258	7.066e-33	142.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
CMS3_k127_980906_4	1120950.KB892748_gene3199	3.499e-115	404.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria,4DPPX@85009|Propionibacteriales	201174|Actinobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_980906_2	1192034.CAP_2756	1.405e-167	535.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_990136_2	502025.Hoch_1912	1.06e-37	146.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	mauB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.4.9.1,1.4.9.2	ko:K13372,ko:K15229	ko00350,ko00360,ko00680,ko00950,ko01100,ko01110,ko01120,map00350,map00360,map00680,map00950,map01100,map01110,map01120	-	R00606,R02382,R02612,R04300	RC00062,RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_H
CMS3_k127_990136_3	502025.Hoch_4223	2.022e-08	66.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,439A0@68525|delta/epsilon subdivisions,2X4HG@28221|Deltaproteobacteria,2YZ10@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_990136_0	1254432.SCE1572_03260	9.369e-147	478.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
CMS3_k127_990136_1	1254432.SCE1572_33980	1.667e-63	247.0	COG2755@1|root,COG2755@2|Bacteria,1R7BU@1224|Proteobacteria,43428@68525|delta/epsilon subdivisions,2X4SY@28221|Deltaproteobacteria,2YZIV@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_994952_3	502025.Hoch_5512	4.024e-188	600.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales	28221|Deltaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
CMS3_k127_994952_7	448385.sce3914	1.138e-48	184.0	COG3177@1|root,COG3177@2|Bacteria,1Q2H9@1224|Proteobacteria,4383Y@68525|delta/epsilon subdivisions,2X3DX@28221|Deltaproteobacteria,2YVMK@29|Myxococcales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
CMS3_k127_994952_5	502025.Hoch_1950	7.166e-110	363.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2YUXX@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS3_k127_994952_9	502025.Hoch_1951	3.594e-13	73.0	COG3116@1|root,COG3116@2|Bacteria	2|Bacteria	D	cell division	ftsL	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
CMS3_k127_994952_1	502025.Hoch_1952	1.43e-217	700.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,2YTT3@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
CMS3_k127_994952_0	502025.Hoch_1954	8.219e-275	872.0	COG0769@1|root,COG0770@1|root,COG0769@2|Bacteria,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,43BV1@68525|delta/epsilon subdivisions,2X760@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.10,6.3.2.13	ko:K15792	ko00300,ko00550,map00300,map00550	-	R02788,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_994952_4	502025.Hoch_1955	2.053e-184	582.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2YWXN@29|Myxococcales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
CMS3_k127_994952_8	1297742.A176_05762	5.447e-17	92.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
CMS3_k127_994952_2	502025.Hoch_1956	1.888e-197	625.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2YU89@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
CMS3_k127_994952_6	502025.Hoch_1957	3.121e-51	194.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS3_k127_996166_2	502025.Hoch_6773	8.153e-43	158.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	pph1	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_996166_0	502025.Hoch_6775	1.704e-114	393.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
CMS3_k127_996166_1	502025.Hoch_6776	2.748e-66	236.0	COG0454@1|root,COG0456@2|Bacteria,1QGYZ@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS3_k127_996166_3	1254432.SCE1572_17160	1.147e-09	59.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2YTZC@29|Myxococcales	28221|Deltaproteobacteria	C	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
## 5804 queries scanned
## Total time (seconds): 230.7877299785614
## Rate: 25.15 q/s