## Sat Nov 9 20:16:05 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS3_bin.131.fa -m mmseqs --itype genome -o CMS3_bin.131 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS3_bin.131 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs CMS3_k127_1050417_5 992406.RIA_0505 7.806e-80 273.0 COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia 976|Bacteroidetes D Di-iron-containing protein involved in the repair of iron-sulfur clusters ric - - ko:K07322 - - - - ko00000 - - - Hemerythrin,ScdA_N CMS3_k127_1050417_7 1122225.AULQ01000005_gene2510 2.662e-50 182.0 COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1I2ZX@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - Rrf2 CMS3_k127_1050417_8 1444309.JAQG01000019_gene523 1.453e-46 172.0 COG3832@1|root,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity - - - - - - - - - - - - AHSA1,PDZ_2,Polyketide_cyc2 CMS3_k127_1050417_4 1121875.KB907549_gene1707 2.828e-157 519.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_1050417_15 1123008.KB905693_gene1330 6.565e-18 88.0 COG4319@1|root,COG4319@2|Bacteria,4NT6G@976|Bacteroidetes,2FTV9@200643|Bacteroidia,22YRG@171551|Porphyromonadaceae 976|Bacteroidetes S Calcium/calmodulin dependent protein kinase II association domain - - - - - - - - - - - - DUF4440 CMS3_k127_1050417_2 1123278.KB893563_gene4537 3.005e-182 583.0 COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,47KIK@768503|Cytophagia 976|Bacteroidetes G PFAM FGGY family of carbohydrate kinases, N-terminal domain xylB_2 - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N CMS3_k127_1050417_0 1121011.AUCB01000015_gene45 1.03e-217 682.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,1HXW8@117743|Flavobacteriia,23G0V@178469|Arenibacter 976|Bacteroidetes G Catalyzes the interconversion of D-xylose to D-xylulose xylA - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - - CMS3_k127_1050417_10 1121904.ARBP01000007_gene3076 4.937e-36 150.0 COG4977@1|root,COG4977@2|Bacteria,4PPMY@976|Bacteroidetes 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_1050417_14 225937.HP15_2144 3.622e-18 97.0 COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,4677J@72275|Alteromonadaceae 1236|Gammaproteobacteria CO Thioredoxin-like resA - - - - - - - - - - - AhpC-TSA,Redoxin CMS3_k127_1050417_13 585.DR95_1535 1.415e-26 120.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,3Z17R@583|Proteus 1236|Gammaproteobacteria U Involved in the TonB-independent uptake of proteins tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N CMS3_k127_1050417_6 929556.Solca_1496 5.148e-79 272.0 COG1670@1|root,COG1670@2|Bacteria,4NUGW@976|Bacteroidetes 976|Bacteroidetes J GNAT acetyltransferase - - - - - - - - - - - - GNAT_acetyltran CMS3_k127_1050417_3 1047013.AQSP01000095_gene2303 6.633e-158 526.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1050417_12 1405.DJ92_3414 1.778e-31 136.0 COG0491@1|root,COG0491@2|Bacteria,1U974@1239|Firmicutes,4IJ9B@91061|Bacilli,1ZN0N@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_1050417_11 1317122.ATO12_01855 2.032e-35 137.0 COG0640@1|root,COG0640@2|Bacteria,4NSYA@976|Bacteroidetes,1I3DD@117743|Flavobacteriia,2YJRM@290174|Aquimarina 976|Bacteroidetes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 CMS3_k127_1050417_1 1286632.P278_00800 2.695e-195 620.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia 976|Bacteroidetes E COG0076 Glutamate decarboxylase and related PLP-dependent - - - - - - - - - - - - Pyridoxal_deC CMS3_k127_1050417_9 204669.Acid345_0069 1.788e-43 173.0 COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria,2JKB5@204432|Acidobacteriia 204432|Acidobacteriia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_1075005_0 929703.KE386491_gene2653 1.419e-254 795.0 COG0008@1|root,COG0008@2|Bacteria,4NFCC@976|Bacteroidetes,47MT0@768503|Cytophagia 976|Bacteroidetes J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C CMS3_k127_1075005_3 929703.KE386491_gene479 1.039e-69 244.0 COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K5B@768503|Cytophagia 976|Bacteroidetes H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase CMS3_k127_1075005_1 1121012.AUKX01000010_gene2027 7.517e-174 559.0 COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1I0X7@117743|Flavobacteriia,23FWQ@178469|Arenibacter 976|Bacteroidetes E Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_1075005_4 655815.ZPR_2499 8.385e-06 50.0 2E97G@1|root,333FY@2|Bacteria,4NWTY@976|Bacteroidetes,1I5KD@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1075005_2 1237149.C900_05709 3.54e-105 349.0 COG0583@1|root,COG0583@2|Bacteria,4NGUF@976|Bacteroidetes,47N1G@768503|Cytophagia 976|Bacteroidetes K LysR substrate binding domain - - - ko:K03576 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate CMS3_k127_1090279_1 1408433.JHXV01000012_gene3982 2.556e-51 185.0 COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia,2PAX6@246874|Cryomorphaceae 976|Bacteroidetes I NUDIX domain idi - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - NUDIX CMS3_k127_1090279_0 760192.Halhy_0344 2.454e-150 492.0 COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia 976|Bacteroidetes L DNA photolyase phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 CMS3_k127_1090279_2 1317122.ATO12_00430 2.122e-50 183.0 COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia,2YIVA@290174|Aquimarina 976|Bacteroidetes S SRPBCC domain-containing protein - - - - - - - - - - - - Polyketide_cyc CMS3_k127_111586_18 226186.BT_4574 2.231e-30 124.0 COG0239@1|root,COG0239@2|Bacteria,4NV3N@976|Bacteroidetes,2FUP5@200643|Bacteroidia,4AR5I@815|Bacteroidaceae 976|Bacteroidetes D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB CMS3_k127_111586_24 255470.cbdbA610 1.512e-10 68.0 COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi,34CZJ@301297|Dehalococcoidia 301297|Dehalococcoidia T HD domain - - - - - - - - - - - - HD,Response_reg CMS3_k127_111586_8 997296.PB1_11979 1.998e-116 384.0 COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,1ZBD0@1386|Bacillus 91061|Bacilli S Carbon-nitrogen hydrolase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase CMS3_k127_111586_14 926562.Oweho_0904 2.193e-58 206.0 COG0727@1|root,COG0727@2|Bacteria,4NJH9@976|Bacteroidetes,1HZQ3@117743|Flavobacteriia,2PAWU@246874|Cryomorphaceae 976|Bacteroidetes S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC CMS3_k127_111586_20 392500.Swoo_4356 1.565e-21 98.0 COG3040@1|root,COG3040@2|Bacteria,1PX5K@1224|Proteobacteria,1T8RX@1236|Gammaproteobacteria,2QE8T@267890|Shewanellaceae 1236|Gammaproteobacteria M lipid binding - - - - - - - - - - - - - CMS3_k127_111586_16 1279009.ADICEAN_00875 6.302e-39 168.0 COG2885@1|root,COG2885@2|Bacteria,4NECX@976|Bacteroidetes 976|Bacteroidetes M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,OmpA CMS3_k127_111586_22 1469557.JSWF01000016_gene2144 1.467e-11 71.0 2AB4R@1|root,310IS@2|Bacteria,4NPUV@976|Bacteroidetes,1I2GC@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - LEA_2 CMS3_k127_111586_10 1237149.C900_04937 1.325e-97 328.0 COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,47MFN@768503|Cytophagia 976|Bacteroidetes C PFAM Glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,Phytase-like CMS3_k127_111586_6 1124780.ANNU01000072_gene1057 3.58e-127 414.0 COG0524@1|root,COG0524@2|Bacteria,4NIHI@976|Bacteroidetes,47NUW@768503|Cytophagia 976|Bacteroidetes G Belongs to the carbohydrate kinase PfkB family - - - - - - - - - - - - PfkB CMS3_k127_111586_17 1237149.C900_05257 2.506e-33 141.0 29N3N@1|root,33SHJ@2|Bacteria,4P1XQ@976|Bacteroidetes,47TMQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_111586_3 1124780.ANNU01000058_gene889 1.799e-200 631.0 COG0626@1|root,COG0626@2|Bacteria,4NIV1@976|Bacteroidetes,47P29@768503|Cytophagia 976|Bacteroidetes E Cys/Met metabolism PLP-dependent enzyme - - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_111586_7 643867.Ftrac_0721 2.667e-120 396.0 COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,47MJP@768503|Cytophagia 976|Bacteroidetes E Putative serine dehydratase domain - - 4.3.1.27 ko:K20757 - - - - ko00000,ko01000 - - - Ala_racemase_N,D-ser_dehydrat CMS3_k127_111586_5 1237149.C900_02886 5.568e-131 445.0 COG0515@1|root,COG0515@2|Bacteria 1237149.C900_02886|- KLT protein kinase activity - - - - - - - - - - - - - CMS3_k127_111586_4 1237149.C900_02885 2.851e-195 618.0 COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,4NE2Y@976|Bacteroidetes,47KD4@768503|Cytophagia 976|Bacteroidetes P COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - - - - - - - - - - Lactamase_B,Rhodanese CMS3_k127_111586_15 1121373.KB903662_gene139 5.028e-49 180.0 COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,47XSN@768503|Cytophagia 976|Bacteroidetes C Haem-binding domain - - - - - - - - - - - - Haem_bd CMS3_k127_111586_1 1189612.A33Q_1529 8.532e-241 750.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47K0E@768503|Cytophagia 976|Bacteroidetes C Dihydrolipoyl dehydrogenase lpd - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim CMS3_k127_111586_2 1120968.AUBX01000011_gene3253 6.646e-216 683.0 COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,47K2Z@768503|Cytophagia 976|Bacteroidetes C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS3_k127_111586_0 1124780.ANNU01000052_gene3583 0.0 1380.0 COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,47JXI@768503|Cytophagia 976|Bacteroidetes C 2-oxoglutarate dehydrogenase, E1 sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr CMS3_k127_111586_13 1124780.ANNU01000052_gene3582 2.17e-58 212.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,47PR5@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 CMS3_k127_111586_19 1189612.A33Q_2243 1.127e-23 106.0 COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,47QUB@768503|Cytophagia 976|Bacteroidetes J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM CMS3_k127_111586_9 761193.Runsl_4094 4.312e-104 342.0 COG0336@1|root,COG0336@2|Bacteria,4NF2Q@976|Bacteroidetes,47MGG@768503|Cytophagia 976|Bacteroidetes J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT CMS3_k127_111586_11 945713.IALB_0441 2.382e-83 283.0 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_111586_12 1191523.MROS_0359 7.948e-79 274.0 COG2972@1|root,COG2972@2|Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - HATPase_c_5,His_kinase CMS3_k127_1122202_0 1237149.C900_01650 5.874e-144 462.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,47MGR@768503|Cytophagia 976|Bacteroidetes EF Ribose-phosphate pyrophosphokinase prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N CMS3_k127_1122202_1 643867.Ftrac_0552 3.867e-77 264.0 COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,47NVP@768503|Cytophagia 976|Bacteroidetes J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C CMS3_k127_1122202_2 643867.Ftrac_0555 6.18e-76 258.0 COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,47Q0M@768503|Cytophagia 976|Bacteroidetes J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro CMS3_k127_1122202_3 886379.AEWI01000026_gene444 2.408e-64 226.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia,3XJMR@558415|Marinilabiliaceae 976|Bacteroidetes J Putative tRNA binding domain metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind CMS3_k127_1132558_0 1121875.KB907553_gene24 6.04e-175 580.0 COG0412@1|root,COG1262@1|root,COG2114@1|root,COG0412@2|Bacteria,COG1262@2|Bacteria,COG2114@2|Bacteria,4PPKM@976|Bacteroidetes 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc CMS3_k127_1132558_1 1121875.KB907556_gene573 1.917e-164 525.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1HXBS@117743|Flavobacteriia 976|Bacteroidetes J Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related - - - - - - - - - - - - Amidase CMS3_k127_1142795_1 616991.JPOO01000001_gene3360 5.12e-65 235.0 COG2207@1|root,COG2207@2|Bacteria,4PI6R@976|Bacteroidetes,1IG3A@117743|Flavobacteriia,23IGX@178469|Arenibacter 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_1142795_0 1237149.C900_04608 2.472e-183 599.0 COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia 976|Bacteroidetes M AsmA-like C-terminal region - - - - - - - - - - - - AsmA,AsmA_2,DUF3971 CMS3_k127_1189156_6 1120965.AUBV01000003_gene635 2.352e-22 100.0 COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,47K3H@768503|Cytophagia 976|Bacteroidetes FP Ppx GppA phosphatase - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA CMS3_k127_1189156_0 1239962.C943_02603 7.004e-272 843.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) pccB - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS3_k127_1189156_5 751944.HALDL1_11185 7.189e-68 237.0 COG1028@1|root,arCOG01259@2157|Archaea,2XV13@28890|Euryarchaeota,23URP@183963|Halobacteria 183963|Halobacteria I COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 CMS3_k127_1189156_1 1237149.C900_01074 4.593e-184 580.0 COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,47MIG@768503|Cytophagia 976|Bacteroidetes G PFAM M42 glutamyl aminopeptidase frvX - - - - - - - - - - - Peptidase_M42 CMS3_k127_1189156_4 926549.KI421517_gene2920 6.811e-97 330.0 COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,47K1U@768503|Cytophagia 976|Bacteroidetes E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase CMS3_k127_1189156_3 1189612.A33Q_3332 5.97e-97 327.0 COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,47JBE@768503|Cytophagia 976|Bacteroidetes E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase CMS3_k127_1189156_2 1237149.C900_01082 8.706e-135 438.0 COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia 976|Bacteroidetes E chorismate mutase pheB - 5.4.99.5 ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,DAHP_synth_1 CMS3_k127_12080_17 1121859.KB890739_gene2158 8.339e-06 52.0 2ESD2@1|root,33JXU@2|Bacteria,4NXJ7@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_12080_15 1237149.C900_05891 1.193e-47 180.0 COG3103@1|root,COG3103@2|Bacteria,4NIH7@976|Bacteroidetes,47P4Z@768503|Cytophagia 976|Bacteroidetes T Sh3 type 3 domain protein - - - - - - - - - - - - SH3_3,SH3_4 CMS3_k127_12080_1 1237149.C900_05890 7.456e-197 643.0 COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes,47MS8@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD CMS3_k127_12080_2 1237149.C900_05889 3.927e-167 542.0 COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,47KB6@768503|Cytophagia 976|Bacteroidetes J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr CMS3_k127_12080_11 1124780.ANNU01000019_gene1703 7.403e-57 199.0 2BXI1@1|root,32R1C@2|Bacteria,4NR9I@976|Bacteroidetes,47QU5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_12080_3 1048983.EL17_03790 1.507e-150 483.0 COG0611@1|root,COG0611@2|Bacteria,4NDUT@976|Bacteroidetes,47JR7@768503|Cytophagia 976|Bacteroidetes H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CMS3_k127_12080_13 866536.Belba_2024 3.516e-53 190.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia 976|Bacteroidetes E PFAM Glyoxalase bleomycin resistance protein dioxygenase mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 CMS3_k127_12080_12 643867.Ftrac_1574 2.547e-53 190.0 2BJ0K@1|root,32D95@2|Bacteria,4NQN9@976|Bacteroidetes,47QR4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_12080_14 1313301.AUGC01000001_gene1801 1.924e-50 180.0 COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes 976|Bacteroidetes S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn CMS3_k127_12080_0 1237149.C900_03692 1.63e-322 995.0 COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,47JRN@768503|Cytophagia 976|Bacteroidetes F PFAM Glutamine amidotransferase, class-II purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7 CMS3_k127_12080_7 1237149.C900_03683 1.283e-112 369.0 COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47MMI@768503|Cytophagia 976|Bacteroidetes M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race CMS3_k127_12080_10 1191523.MROS_0345 3.259e-66 229.0 COG2110@1|root,COG2110@2|Bacteria 2|Bacteria P phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - - - - - - - - - - Macro CMS3_k127_12080_5 1237149.C900_03682 1.557e-142 456.0 COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,47KZ9@768503|Cytophagia 976|Bacteroidetes I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_12080_9 694427.Palpr_0822 3.653e-76 263.0 COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,2FM2B@200643|Bacteroidia,22X69@171551|Porphyromonadaceae 976|Bacteroidetes F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CMS3_k127_12080_8 1237149.C900_03679 1.155e-89 304.0 COG0697@1|root,COG0697@2|Bacteria,4NE8D@976|Bacteroidetes,47JNH@768503|Cytophagia 976|Bacteroidetes EG PFAM EamA-like transporter family - - - - - - - - - - - - EamA CMS3_k127_12080_6 1237149.C900_03678 8.265e-130 423.0 COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes,47JHT@768503|Cytophagia 976|Bacteroidetes S Permease YjgP YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ CMS3_k127_12080_4 643867.Ftrac_0312 4.072e-144 460.0 COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,47JEY@768503|Cytophagia 976|Bacteroidetes J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT CMS3_k127_1212743_4 1009370.ALO_01429 3.482e-09 59.0 2AV93@1|root,31M00@2|Bacteria,1V94N@1239|Firmicutes,4H7KF@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - CMS3_k127_1212743_2 871963.Desdi_0799 4.186e-52 194.0 COG1143@1|root,COG1143@2|Bacteria,1UIF0@1239|Firmicutes,25EKC@186801|Clostridia,2657D@186807|Peptococcaceae 186801|Clostridia C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4 CMS3_k127_1212743_0 861299.J421_0786 3.932e-282 884.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT4G@142182|Gemmatimonadetes 142182|Gemmatimonadetes EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_1212743_3 404589.Anae109_2420 1.432e-37 156.0 2DEK6@1|root,2ZNAE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1212743_1 1313421.JHBV01000016_gene5527 1.043e-54 202.0 COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1IWYM@117747|Sphingobacteriia 976|Bacteroidetes S Pregnancy-associated plasma protein-A - - - - - - - - - - - - Peptidase_M43 CMS3_k127_1235043_0 1237149.C900_05293 4.144e-146 476.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_1235043_1 1408473.JHXO01000012_gene293 6.755e-76 258.0 COG2353@1|root,COG2353@2|Bacteria,4NNMD@976|Bacteroidetes,2FVBK@200643|Bacteroidia 976|Bacteroidetes S YceI-like domain - - - - - - - - - - - - YceI CMS3_k127_1235043_2 1123278.KB893582_gene1095 6.334e-60 213.0 COG0664@1|root,COG0664@2|Bacteria,4NM4K@976|Bacteroidetes,47PUR@768503|Cytophagia 976|Bacteroidetes K Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - Crp,cNMP_binding CMS3_k127_1249352_12 313603.FB2170_14718 6.85e-28 114.0 COG1960@1|root,COG1960@2|Bacteria,4NEM4@976|Bacteroidetes,1I0VR@117743|Flavobacteriia,2PHW4@252356|Maribacter 976|Bacteroidetes C Acetyl-CoA dehydrogenase C-terminal like - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N CMS3_k127_1249352_5 760192.Halhy_4520 9.453e-180 574.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_1249352_10 1123277.KB893194_gene5828 1.01e-41 156.0 2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DoxX_2 CMS3_k127_1249352_4 1191523.MROS_0028 2.638e-212 669.0 COG2160@1|root,COG2160@2|Bacteria 2|Bacteria G L-arabinose isomerase activity araA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060 Arabinose_Iso_C,Arabinose_Isome CMS3_k127_1249352_2 1121904.ARBP01000027_gene735 3.447e-282 878.0 COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,47U48@768503|Cytophagia 976|Bacteroidetes S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family sglT - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_1249352_9 926549.KI421517_gene1213 2.284e-110 360.0 COG0235@1|root,COG0235@2|Bacteria,4NGMP@976|Bacteroidetes,47MSX@768503|Cytophagia 976|Bacteroidetes G PFAM Class II Aldolase and Adducin N-terminal domain araD - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II CMS3_k127_1249352_3 700598.Niako_3636 9.373e-231 726.0 COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,1IQ36@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the ribulokinase family araB - 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N CMS3_k127_1249352_1 929562.Emtol_2210 7.075e-290 902.0 COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47NJB@768503|Cytophagia 976|Bacteroidetes S Beta-L-arabinofuranosidase, GH127 - - - ko:K09955 - - - - ko00000 - - - Glyco_hydro_127 CMS3_k127_1249352_8 926549.KI421517_gene3752 8.336e-131 427.0 COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,47KAR@768503|Cytophagia 976|Bacteroidetes G Converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim CMS3_k127_1249352_13 1507.HMPREF0262_01211 1.113e-27 117.0 COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia,36JK7@31979|Clostridiaceae 186801|Clostridia M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_1249352_0 1454007.JAUG01000053_gene2497 0.0 1054.0 COG1262@1|root,COG1262@2|Bacteria,4NJRT@976|Bacteroidetes,1IVR7@117747|Sphingobacteriia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS3_k127_1249352_7 471854.Dfer_2569 3.746e-136 445.0 2CD20@1|root,2ZA3P@2|Bacteria,4NHWK@976|Bacteroidetes,47N3B@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1249352_6 926556.Echvi_1437 3.528e-168 539.0 COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,47U2I@768503|Cytophagia 976|Bacteroidetes V PFAM Inner membrane protein CreD creD - - ko:K06143 - - - - ko00000 - - - CreD CMS3_k127_1249352_11 1239962.C943_00711 2.703e-33 132.0 COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,47R9V@768503|Cytophagia 976|Bacteroidetes K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_34 CMS3_k127_1249352_14 643867.Ftrac_3773 4.954e-10 60.0 COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,47P7G@768503|Cytophagia 976|Bacteroidetes Q membrane - - - - - - - - - - - - - CMS3_k127_1279371_17 485918.Cpin_6205 1.817e-21 107.0 COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,1IPFV@117747|Sphingobacteriia 976|Bacteroidetes KT BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M56 CMS3_k127_1279371_15 1484460.JSWG01000009_gene474 2.979e-26 111.0 COG0640@1|root,COG0640@2|Bacteria,4NR48@976|Bacteroidetes,1I39F@117743|Flavobacteriia 976|Bacteroidetes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 CMS3_k127_1279371_2 1469557.JSWF01000028_gene3041 2.677e-180 580.0 COG2234@1|root,COG2234@2|Bacteria,4NIAY@976|Bacteroidetes,1HZ2X@117743|Flavobacteriia 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 CMS3_k127_1279371_1 1237149.C900_01148 8.147e-283 875.0 COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_1279371_14 760192.Halhy_4272 9.297e-27 115.0 COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,1IUMH@117747|Sphingobacteriia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_1279371_4 1288963.ADIS_2787 3.829e-73 256.0 COG0111@1|root,COG0111@2|Bacteria,4NE9J@976|Bacteroidetes,47JBD@768503|Cytophagia 976|Bacteroidetes EH D-isomer specific 2-hydroxyacid dehydrogenase ghrA - 1.1.1.79,1.1.1.81 ko:K12972 ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R01388,R01392,R02527 RC00031,RC00042,RC00670 ko00000,ko00001,ko01000 - - - 2-Hacid_dh_C CMS3_k127_1279371_13 313606.M23134_02861 1.624e-29 122.0 COG2885@1|root,COG2885@2|Bacteria,4P5MU@976|Bacteroidetes 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA CMS3_k127_1279371_6 1237149.C900_05477 2.666e-55 198.0 COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_1279371_16 1185876.BN8_02183 2.574e-23 110.0 COG1413@1|root,COG1413@2|Bacteria,4NKJR@976|Bacteroidetes,47NH6@768503|Cytophagia 976|Bacteroidetes C HEAT repeats - - - - - - - - - - - - HEAT_2 CMS3_k127_1279371_9 1218108.KB908302_gene2742 6.347e-44 171.0 COG3595@1|root,COG3595@2|Bacteria,4NKSN@976|Bacteroidetes,1I2JR@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4097 CMS3_k127_1279371_11 1237149.C900_05480 3.349e-39 156.0 COG3595@1|root,COG3595@2|Bacteria,4NT4J@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1279371_3 1121875.KB907547_gene3381 2.297e-156 505.0 COG1288@1|root,COG1288@2|Bacteria,4NEUI@976|Bacteroidetes,1HYKQ@117743|Flavobacteriia 976|Bacteroidetes S C4-dicarboxylate anaerobic carrier - - - - - - - - - - - - DcuC CMS3_k127_1279371_12 1484460.JSWG01000001_gene2089 1.115e-35 142.0 COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NKQV@976|Bacteroidetes,1HYSN@117743|Flavobacteriia 976|Bacteroidetes T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - CMS3_k127_1279371_7 1178825.ALIH01000007_gene1710 3.486e-53 194.0 COG0346@1|root,COG0346@2|Bacteria,4NN6H@976|Bacteroidetes,1I2IV@117743|Flavobacteriia 976|Bacteroidetes E Glyoxalase-like domain - - - ko:K07032 - - - - ko00000 - - - Glyoxalase CMS3_k127_1279371_8 1296416.JACB01000029_gene4242 3.597e-51 182.0 COG0640@1|root,COG0640@2|Bacteria,4NTCN@976|Bacteroidetes,1IJ3T@117743|Flavobacteriia,2YM5I@290174|Aquimarina 976|Bacteroidetes K Sugar-specific transcriptional regulator TrmB - - - - - - - - - - - - HTH_20,HTH_5 CMS3_k127_1279371_5 1317122.ATO12_05730 7.53e-73 248.0 COG3832@1|root,COG3832@2|Bacteria,4NR9F@976|Bacteroidetes,1IGFV@117743|Flavobacteriia,2YHDA@290174|Aquimarina 976|Bacteroidetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 CMS3_k127_1279371_0 760192.Halhy_6518 0.0 1032.0 COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IR4V@117747|Sphingobacteriia 976|Bacteroidetes E peptidase S9B dipeptidylpeptidase IV domain protein - - - - - - - - - - - - DPPIV_N,Peptidase_S9 CMS3_k127_1279371_10 1121346.KB899855_gene105 2.265e-41 163.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,26RYV@186822|Paenibacillaceae 91061|Bacilli O Peptidase S8 epr - 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 CMS3_k127_1329093_8 309801.trd_0147 0.0006524 42.0 COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi,27YVD@189775|Thermomicrobia 189775|Thermomicrobia C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_8 CMS3_k127_1329093_0 313603.FB2170_11651 0.0 1450.0 COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI8X@252356|Maribacter 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_1329093_5 1250232.JQNJ01000001_gene3522 1.303e-69 248.0 COG2207@1|root,COG2207@2|Bacteria,4NF8Q@976|Bacteroidetes,1I16E@117743|Flavobacteriia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_1329093_3 1283300.ATXB01000002_gene2890 7.867e-116 387.0 COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,1RNY6@1236|Gammaproteobacteria 1236|Gammaproteobacteria C ATP ADP translocase - - - ko:K03301 - - - - ko00000 2.A.12 - - MFS_1,TLC CMS3_k127_1329093_2 471854.Dfer_0310 6.507e-116 380.0 COG0656@1|root,COG0656@2|Bacteria,4NK47@976|Bacteroidetes,47MZY@768503|Cytophagia 976|Bacteroidetes S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CMS3_k127_1329093_6 1293054.HSACCH_02658 2.616e-30 130.0 COG2819@1|root,COG2819@2|Bacteria,1UZZZ@1239|Firmicutes,248ZU@186801|Clostridia,3WC1W@53433|Halanaerobiales 186801|Clostridia S Putative esterase - - - - - - - - - - - - Esterase CMS3_k127_1329093_4 1408813.AYMG01000017_gene5590 2.369e-89 298.0 COG3145@1|root,COG3145@2|Bacteria,4NFEG@976|Bacteroidetes,1INR0@117747|Sphingobacteriia 976|Bacteroidetes L PFAM 2OG-Fe(II) oxygenase superfamily - - - - - - - - - - - - 2OG-FeII_Oxy_2 CMS3_k127_1329093_7 714943.Mucpa_3014 2.82e-22 98.0 COG2169@1|root,COG2169@2|Bacteria,4NV90@976|Bacteroidetes,1IU0R@117747|Sphingobacteriia 976|Bacteroidetes F Metal binding domain of Ada - - - - - - - - - - - - Ada_Zn_binding CMS3_k127_1329093_1 925409.KI911562_gene1457 1.476e-120 389.0 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,1IP7V@117747|Sphingobacteriia 976|Bacteroidetes K 6-O-methylguanine DNA methyltransferase, DNA binding domain ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,HTH_18,Methyltransf_1N CMS3_k127_1363927_27 1237149.C900_05121 7.995e-18 88.0 2ECXC@1|root,336UI@2|Bacteria,4NV8T@976|Bacteroidetes,47RWP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1363927_24 643867.Ftrac_0761 4.194e-30 123.0 COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,47SC6@768503|Cytophagia 976|Bacteroidetes U PFAM Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG CMS3_k127_1363927_19 313606.M23134_02308 3.033e-83 282.0 28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1363927_22 1121904.ARBP01000016_gene5228 4.051e-43 158.0 COG0234@1|root,COG0234@2|Bacteria,4NS7D@976|Bacteroidetes,47QCW@768503|Cytophagia 976|Bacteroidetes O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 CMS3_k127_1363927_0 1237149.C900_05125 4.518e-287 888.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,47JYW@768503|Cytophagia 976|Bacteroidetes O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 CMS3_k127_1363927_28 1124780.ANNU01000049_gene2212 1.57e-10 66.0 2AD7J@1|root,312WH@2|Bacteria 2|Bacteria S Domain of unknown function (DUF1987) - - - - - - - - - - - - DUF1987 CMS3_k127_1363927_3 760192.Halhy_4006 1.002e-226 711.0 COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1IP39@117747|Sphingobacteriia 976|Bacteroidetes E COG3104 Dipeptide tripeptide permease - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 CMS3_k127_1363927_1 1279009.ADICEAN_02424 1.872e-275 854.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,47JC3@768503|Cytophagia 976|Bacteroidetes H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CMS3_k127_1363927_4 1443665.JACA01000022_gene5111 5.242e-183 584.0 COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia,2YHQF@290174|Aquimarina 976|Bacteroidetes F Na+ dependent nucleoside transporter C-terminus nupC - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N CMS3_k127_1363927_18 1237149.C900_05134 9.824e-86 287.0 COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,47KJI@768503|Cytophagia 976|Bacteroidetes L PFAM Uncharacterised ACR, COG1259 - - - ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR CMS3_k127_1363927_9 1237149.C900_05135 1.192e-147 473.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,47JUQ@768503|Cytophagia 976|Bacteroidetes C Electron transfer flavoprotein, alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha CMS3_k127_1363927_11 1237149.C900_05136 1.638e-120 390.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,47KZ2@768503|Cytophagia 976|Bacteroidetes C Electron transfer flavoprotein etfB - - ko:K03521 - - - - ko00000 - - - ETF CMS3_k127_1363927_20 643867.Ftrac_2982 1.449e-80 278.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF CMS3_k127_1363927_23 991.IW20_20825 4.537e-35 148.0 COG4932@1|root,COG4935@1|root,COG4932@2|Bacteria,COG4935@2|Bacteria,4PKCH@976|Bacteroidetes,1IJ7H@117743|Flavobacteriia,2P0K8@237|Flavobacterium 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,DUF11,SdrD_B CMS3_k127_1363927_26 1296416.JACB01000029_gene4121 1.65e-18 97.0 COG5295@1|root,COG5295@2|Bacteria,4NH9J@976|Bacteroidetes,1HYNF@117743|Flavobacteriia 976|Bacteroidetes UW domain protein - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - YadA_head CMS3_k127_1363927_29 1137281.D778_02636 9.394e-09 63.0 COG0457@1|root,COG0457@2|Bacteria,4NQ3P@976|Bacteroidetes,1I2ED@117743|Flavobacteriia 976|Bacteroidetes S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_6 CMS3_k127_1363927_2 1237149.C900_05140 7.735e-241 752.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C CMS3_k127_1363927_7 1279009.ADICEAN_03945 3.01e-160 516.0 COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,47JEX@768503|Cytophagia 976|Bacteroidetes M Mur ligase middle domain mpl - 6.3.2.45,6.3.2.8 ko:K01924,ko:K02558 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS3_k127_1363927_13 1237149.C900_05142 4.519e-111 364.0 COG0847@1|root,COG0847@2|Bacteria,4NE82@976|Bacteroidetes,47N5P@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T CMS3_k127_1363927_14 1237149.C900_00936 1.185e-107 354.0 COG4783@1|root,COG4783@2|Bacteria,4PKN7@976|Bacteroidetes,47YC0@768503|Cytophagia 976|Bacteroidetes S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 CMS3_k127_1363927_17 1237149.C900_00937 2.391e-99 327.0 COG0179@1|root,COG0179@2|Bacteria,4NGCT@976|Bacteroidetes,47MHB@768503|Cytophagia 976|Bacteroidetes Q PFAM fumarylacetoacetate (FAA) hydrolase fahA - - - - - - - - - - - FAA_hydrolase CMS3_k127_1363927_5 1237149.C900_00938 1.638e-163 535.0 COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,47JZB@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 CMS3_k127_1363927_21 1237149.C900_05652 3.927e-70 240.0 COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,47PUA@768503|Cytophagia 976|Bacteroidetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA CMS3_k127_1363927_10 643867.Ftrac_0981 2.543e-141 452.0 COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,47JJD@768503|Cytophagia 976|Bacteroidetes G PFAM Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N CMS3_k127_1363927_6 1237149.C900_00613 3.84e-163 519.0 COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,47JQN@768503|Cytophagia 976|Bacteroidetes G PFAM Transketolase, C-terminal domain dxs - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C CMS3_k127_1363927_8 1237149.C900_00593 4.737e-159 511.0 COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,47JJU@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_1363927_15 886379.AEWI01000007_gene762 1.712e-106 356.0 COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,2FMH5@200643|Bacteroidia,3XIID@558415|Marinilabiliaceae 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - DUF1624,DUF5009 CMS3_k127_1363927_16 1237149.C900_01420 2.385e-102 346.0 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia 976|Bacteroidetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ccmG - - - - - - - - - - - AhpC-TSA,DUF4369 CMS3_k127_1363927_12 1305737.JAFX01000001_gene295 6.95e-117 378.0 COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,47JX6@768503|Cytophagia 976|Bacteroidetes G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA CMS3_k127_1363927_25 1237149.C900_05060 1.096e-27 113.0 COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,47MP4@768503|Cytophagia 976|Bacteroidetes D PFAM ABC transporter ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran CMS3_k127_137401_4 1286632.P278_03710 1.711e-10 62.0 COG2044@1|root,COG2044@2|Bacteria,4P2I4@976|Bacteroidetes,1I8SH@117743|Flavobacteriia 976|Bacteroidetes S DsrE/DsrF-like family - - - - - - - - - - - - DrsE CMS3_k127_137401_1 305900.GV64_04920 2.47e-67 235.0 COG0702@1|root,COG0702@2|Bacteria,1QR3E@1224|Proteobacteria,1S37H@1236|Gammaproteobacteria 1236|Gammaproteobacteria GM epimerase - - - - - - - - - - - - Epimerase,NAD_binding_10,Semialdhyde_dh CMS3_k127_137401_6 373994.Riv7116_6509 0.0005251 48.0 29BEN@1|root,30XE7@2|Bacteria,1GD88@1117|Cyanobacteria 1117|Cyanobacteria S Protein of unknown function with HXXEE motif - - - - - - - - - - - - HXXEE CMS3_k127_137401_0 742817.HMPREF9449_01310 3.711e-160 513.0 COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,2FNNA@200643|Bacteroidia,22W6P@171551|Porphyromonadaceae 976|Bacteroidetes C NADH:flavin oxidoreductase / NADH oxidase family namA - - - - - - - - - - - Oxidored_FMN CMS3_k127_137401_2 742817.HMPREF9449_01309 3.735e-59 214.0 COG0300@1|root,COG0300@2|Bacteria,4NIAI@976|Bacteroidetes,2FRZY@200643|Bacteroidia,22XM7@171551|Porphyromonadaceae 976|Bacteroidetes S KR domain - - - ko:K07124 - - - - ko00000 - - - adh_short CMS3_k127_137401_3 566466.NOR53_1919 7.775e-11 68.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,1S3BH@1236|Gammaproteobacteria,1J9WR@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria T Sh3 type 3 domain protein - - - - - - - - - - - - AMIN CMS3_k127_137401_5 1469245.JFBG01000071_gene66 0.0002323 49.0 COG0457@1|root,COG0457@2|Bacteria,1N8DP@1224|Proteobacteria,1SDM6@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_137564_4 926556.Echvi_3383 5.173e-145 464.0 COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,47JZ3@768503|Cytophagia 976|Bacteroidetes D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA CMS3_k127_137564_3 1237149.C900_00266 1.442e-219 698.0 COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,47K9B@768503|Cytophagia 976|Bacteroidetes L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 CMS3_k127_137564_1 1048983.EL17_01920 4.227e-224 699.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia 976|Bacteroidetes H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 CMS3_k127_137564_9 1237149.C900_05671 1.776e-50 186.0 2CYF8@1|root,32T43@2|Bacteria,4NUAU@976|Bacteroidetes,47RBY@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_137564_5 1237149.C900_05670 1.106e-139 447.0 COG0496@1|root,COG0496@2|Bacteria,4NEJ5@976|Bacteroidetes,47JN8@768503|Cytophagia 976|Bacteroidetes S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE CMS3_k127_137564_0 1237149.C900_05195 1.182e-310 972.0 COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,47K5C@768503|Cytophagia 976|Bacteroidetes L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII CMS3_k127_137564_2 1237149.C900_05208 6.783e-223 709.0 COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,47M2A@768503|Cytophagia 976|Bacteroidetes O COGs COG1331 Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH CMS3_k127_137564_6 1237149.C900_05209 3.113e-107 358.0 COG2755@1|root,COG2755@2|Bacteria,4NFN6@976|Bacteroidetes,47JI4@768503|Cytophagia 976|Bacteroidetes E PFAM GSCFA family - - - - - - - - - - - - GSCFA CMS3_k127_137564_7 153721.MYP_2348 1.324e-58 206.0 COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,47PY1@768503|Cytophagia 976|Bacteroidetes J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N CMS3_k127_137564_10 1237149.C900_05223 1.329e-40 151.0 COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,47R23@768503|Cytophagia 976|Bacteroidetes J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 CMS3_k127_137564_8 153721.MYP_2346 2.005e-51 184.0 COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia 976|Bacteroidetes J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 CMS3_k127_137564_12 1408813.AYMG01000030_gene679 1.836e-10 68.0 2DPQ3@1|root,332XU@2|Bacteria,4NX0W@976|Bacteroidetes,1IU7V@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_137564_13 1121897.AUGO01000008_gene2742 3.998e-09 60.0 COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1I2TY@117743|Flavobacteriia,2NZZ4@237|Flavobacterium 976|Bacteroidetes UW Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen,Peptidase_S74 CMS3_k127_1377715_2 1237149.C900_04399 2.105e-160 515.0 COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,47KTS@768503|Cytophagia 976|Bacteroidetes O Zn-dependent protease with chaperone function - - 3.4.24.84 ko:K03799,ko:K06013 ko00900,ko01130,map00900,map01130 M00743 R09845 RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N CMS3_k127_1377715_3 1237149.C900_01598 1.744e-120 398.0 COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia 976|Bacteroidetes P TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF CMS3_k127_1377715_0 1237149.C900_01599 2.662e-210 715.0 COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,47MGN@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD CMS3_k127_1377715_6 643867.Ftrac_1276 6.676e-24 104.0 2E5E8@1|root,33066@2|Bacteria,4NWR2@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1377715_8 1227499.C493_02101 5.943e-19 91.0 COG0824@1|root,arCOG01137@2157|Archaea,2XZ99@28890|Euryarchaeota,23WUB@183963|Halobacteria 183963|Halobacteria S Thioesterase superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 CMS3_k127_1377715_5 504472.Slin_1394 2.698e-108 359.0 COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia 976|Bacteroidetes J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine sua5 - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC CMS3_k127_1377715_1 1237149.C900_01604 1.579e-190 601.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,47K8V@768503|Cytophagia 976|Bacteroidetes G Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK CMS3_k127_1377715_9 1122176.KB903532_gene2627 1.775e-09 61.0 COG4568@1|root,COG4568@2|Bacteria,4NXSW@976|Bacteroidetes 976|Bacteroidetes K rho-dependent transcription termination - - - ko:K19000 - - - - ko00000,ko03021 - - - - CMS3_k127_1377715_7 996637.SGM_3570 2.159e-23 109.0 COG0662@1|root,COG0662@2|Bacteria,2IHNU@201174|Actinobacteria 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 CMS3_k127_1377715_10 326297.Sama_1819 1.34e-06 57.0 COG4319@1|root,COG4319@2|Bacteria,1N8AM@1224|Proteobacteria,1SSA6@1236|Gammaproteobacteria,2QAR8@267890|Shewanellaceae 1236|Gammaproteobacteria S ketosteroid isomerase - - - - - - - - - - - - DUF4440 CMS3_k127_1377715_4 1047013.AQSP01000121_gene2702 3.751e-119 403.0 COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria 2|Bacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 CMS3_k127_1396334_7 1121904.ARBP01000009_gene4328 7.827e-21 99.0 COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia 976|Bacteroidetes KT PFAM Peptidase M56, BlaR1 - - - - - - - - - - - - Peptidase_M56 CMS3_k127_1396334_4 1358423.N180_16145 2.267e-39 149.0 COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia 976|Bacteroidetes K Transcriptional repressor, CopY family - - - - - - - - - - - - Penicillinase_R CMS3_k127_1396334_2 643867.Ftrac_1925 5.258e-125 409.0 COG1226@1|root,COG1226@2|Bacteria,4NMSS@976|Bacteroidetes,47UA5@768503|Cytophagia 976|Bacteroidetes P TrkA-N domain - - - - - - - - - - - - Ion_trans_2,TrkA_N CMS3_k127_1396334_5 643867.Ftrac_1924 4.936e-31 138.0 COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NJKM@976|Bacteroidetes,47NZZ@768503|Cytophagia 976|Bacteroidetes KT Stage II sporulation protein E (SpoIIE) - - - - - - - - - - - - SpoIIE,TPR_12,TPR_8 CMS3_k127_1396334_0 1121904.ARBP01000012_gene1304 1.691e-245 770.0 COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,47M6V@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 CMS3_k127_1396334_6 1121011.AUCB01000032_gene1978 9.54e-24 121.0 COG2931@1|root,COG5384@1|root,COG2931@2|Bacteria,COG5384@2|Bacteria,4PKHZ@976|Bacteroidetes,1IK83@117743|Flavobacteriia,23H69@178469|Arenibacter 976|Bacteroidetes J C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,TSP_3 CMS3_k127_1396334_8 383372.Rcas_2841 1.658e-13 87.0 COG1572@1|root,COG1572@2|Bacteria,2G83M@200795|Chloroflexi,377MG@32061|Chloroflexia 32061|Chloroflexia Q CARDB - - - - - - - - - - - - CARDB,Chlam_PMP,DUF1573 CMS3_k127_1396334_1 391598.FBBAL38_08809 2.923e-155 556.0 COG1470@1|root,COG2133@1|root,COG2304@1|root,COG2706@1|root,COG3209@1|root,COG3291@1|root,COG3420@1|root,COG4733@1|root,COG5279@1|root,COG1470@2|Bacteria,COG2133@2|Bacteria,COG2304@2|Bacteria,COG2706@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,COG5279@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia 976|Bacteroidetes DZ TIGRFAM Bacterial surface protein 26-residue repeat - - - - - - - - - - - - CHU_C,Cadherin,DUF285,TIG,TSP_3 CMS3_k127_1396334_3 313603.FB2170_07035 4.865e-76 294.0 COG2304@1|root,COG3291@1|root,COG5183@1|root,COG5644@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,COG5183@2|Bacteria,COG5644@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia,2PI55@252356|Maribacter 976|Bacteroidetes DZ Mycoplasma protein of unknown function, DUF285 - - - - - - - - - - - - CHU_C,Cadherin,DUF285,TIG,TSP_3 CMS3_k127_142753_1 1237149.C900_00659 4.843e-127 419.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,PAS_8 CMS3_k127_142753_0 313606.M23134_06842 3.575e-225 704.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold nagA - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_142753_4 1123256.KB907925_gene1426 9.689e-07 59.0 28KNT@1|root,2ZA6Z@2|Bacteria,1R4VT@1224|Proteobacteria,1S5JM@1236|Gammaproteobacteria,1X6JZ@135614|Xanthomonadales 135614|Xanthomonadales S EthD domain - - - - - - - - - - - - EthD CMS3_k127_142753_2 946362.XP_004990555.1 9.814e-56 209.0 COG0451@1|root,KOG1430@2759|Eukaryota,38E2M@33154|Opisthokonta 33154|Opisthokonta EI 3-beta-hydroxy-delta5-steroid dehydrogenase activity ERG26 GO:0000003,GO:0000166,GO:0000252,GO:0003006,GO:0003674,GO:0003824,GO:0003854,GO:0004769,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0005783,GO:0005789,GO:0006066,GO:0006629,GO:0006694,GO:0006696,GO:0006700,GO:0006702,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007548,GO:0008150,GO:0008152,GO:0008202,GO:0008204,GO:0008207,GO:0008209,GO:0008289,GO:0008406,GO:0008584,GO:0008610,GO:0009058,GO:0009719,GO:0009725,GO:0009889,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010288,GO:0010817,GO:0010959,GO:0012505,GO:0014070,GO:0016020,GO:0016125,GO:0016126,GO:0016128,GO:0016129,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016853,GO:0016860,GO:0016863,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019866,GO:0021537,GO:0021543,GO:0021761,GO:0021766,GO:0022414,GO:0030154,GO:0030283,GO:0030900,GO:0031090,GO:0031960,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031984,GO:0032501,GO:0032502,GO:0032879,GO:0033327,GO:0033764,GO:0033993,GO:0034698,GO:0034754,GO:0034756,GO:0034757,GO:0036094,GO:0042175,GO:0042180,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043269,GO:0043271,GO:0044107,GO:0044108,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045137,GO:0046165,GO:0046546,GO:0046661,GO:0046686,GO:0046890,GO:0048037,GO:0048513,GO:0048519,GO:0048545,GO:0048608,GO:0048731,GO:0048856,GO:0048869,GO:0050662,GO:0050789,GO:0050810,GO:0050896,GO:0051049,GO:0051051,GO:0051287,GO:0051384,GO:0051385,GO:0051412,GO:0055114,GO:0060322,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0080090,GO:0097159,GO:0097305,GO:0097384,GO:0098827,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617,GO:1901654,GO:1901700,GO:1902652,GO:1902653 1.1.1.145,1.1.1.170,1.1.1.181,5.3.3.1 ko:K00070,ko:K07748,ko:K12408 ko00100,ko00120,ko00140,ko01100,ko01130,ko04913,ko04925,ko04927,ko04934,map00100,map00120,map00140,map01100,map01130,map04913,map04925,map04927,map04934 M00101,M00104,M00107,M00110 R01837,R02216,R02499,R02840,R03327,R04163,R04263,R04678,R04849,R07494,R08721,R08723,R08724,R08728 RC00146,RC01111,RC01163 ko00000,ko00001,ko00002,ko01000 - - - 3Beta_HSD CMS3_k127_142753_3 946077.W5A_01285 3.05e-38 149.0 2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4382) - - - - - - - - - - - - CarboxypepD_reg,DUF4382 CMS3_k127_1446888_1 1408473.JHXO01000001_gene2311 8.857e-101 339.0 COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,2FN6I@200643|Bacteroidia 976|Bacteroidetes EH Anthranilate synthase component I trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind CMS3_k127_1446888_0 700598.Niako_5256 7.615e-292 915.0 COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,1IP7E@117747|Sphingobacteriia 976|Bacteroidetes S COGs COG3533 conserved - - - ko:K09955 - - - - ko00000 - - - DUF4986,Glyco_hydro_127 CMS3_k127_1446888_2 216432.CA2559_00255 6.849e-49 178.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1I18C@117743|Flavobacteriia 976|Bacteroidetes K AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_1449946_0 1122176.KB903546_gene1037 1.909e-258 816.0 COG5373@1|root,COG5373@2|Bacteria,4NGKV@976|Bacteroidetes,1IP94@117747|Sphingobacteriia 976|Bacteroidetes S membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 CMS3_k127_1449946_4 1122621.ATZA01000039_gene2599 6.47e-90 325.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1449946_14 1121011.AUCB01000001_gene615 2.018e-06 52.0 COG1960@1|root,COG1960@2|Bacteria,4NEM4@976|Bacteroidetes,1I0VR@117743|Flavobacteriia,23I8J@178469|Arenibacter 976|Bacteroidetes I Acetyl-CoA dehydrogenase C-terminal like - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N CMS3_k127_1449946_6 195250.CM001776_gene345 3.852e-62 246.0 COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria,1GZQ3@1129|Synechococcus 1117|Cyanobacteria M WD domain, G-beta repeat - - - - - - - - - - - - WD40 CMS3_k127_1449946_7 221288.JH992901_gene5748 8.185e-61 241.0 COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria 1117|Cyanobacteria A WD domain, G-beta repeat - - - - - - - - - - - - WD40 CMS3_k127_1449946_13 313596.RB2501_04510 3.274e-07 63.0 2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia 976|Bacteroidetes S TIR domain - - - - - - - - - - - - TIR_2 CMS3_k127_1449946_9 1158609.I586_02704 1.705e-40 159.0 COG1670@1|root,COG1670@2|Bacteria,1V5BA@1239|Firmicutes,4HHR5@91061|Bacilli,4B0VX@81852|Enterococcaceae 91061|Bacilli J Acetyltransferase (GNAT) domain ydaF_1 - - - - - - - - - - - Acetyltransf_3 CMS3_k127_1449946_10 1237149.C900_03331 1.782e-38 151.0 COG0484@1|root,COG0484@2|Bacteria 2|Bacteria O heat shock protein binding - - - - - - - - - - - - - CMS3_k127_1449946_3 1237149.C900_03330 9.454e-144 463.0 COG1054@1|root,COG1054@2|Bacteria,4NEG6@976|Bacteroidetes,47JH6@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0176 family yceA - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C CMS3_k127_1449946_5 313606.M23134_00672 1.945e-86 289.0 COG0521@1|root,COG0521@2|Bacteria,4PIS5@976|Bacteroidetes,47KA4@768503|Cytophagia 976|Bacteroidetes H Probable molybdopterin binding domain - - 2.7.7.75 ko:K03831 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth CMS3_k127_1449946_8 1279009.ADICEAN_01481 1.518e-56 207.0 28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,47SGM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1449946_1 1237149.C900_01787 3.592e-180 574.0 COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 CMS3_k127_1449946_2 1307436.PBF_17539 8.468e-147 467.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,1ZAUT@1386|Bacillus 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt CMS3_k127_1449946_11 866536.Belba_2118 1.338e-37 142.0 COG1760@1|root,COG1760@2|Bacteria,4NFXU@976|Bacteroidetes,47NN2@768503|Cytophagia 976|Bacteroidetes E Serine dehydratase - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_beta CMS3_k127_1456247_3 1443665.JACA01000035_gene2353 3.587e-187 602.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HYZH@117743|Flavobacteriia,2YISC@290174|Aquimarina 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_1456247_12 1237149.C900_00291 1.538e-47 174.0 2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 CMS3_k127_1456247_15 1121904.ARBP01000003_gene6334 8.526e-43 167.0 COG4632@1|root,COG4632@2|Bacteria,4NQZB@976|Bacteroidetes,47Q6A@768503|Cytophagia 976|Bacteroidetes G Phosphodiester glycosidase - - - - - - - - - - - - NAGPA CMS3_k127_1456247_11 927658.AJUM01000043_gene812 8.179e-51 191.0 COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,2FMGJ@200643|Bacteroidia,3XIV5@558415|Marinilabiliaceae 976|Bacteroidetes I Diacylglycerol kinase catalytic domain (presumed) - - - - - - - - - - - - DAGK_cat CMS3_k127_1456247_5 929562.Emtol_2575 3.53e-134 459.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_1456247_20 504472.Slin_3773 1.689e-27 116.0 COG1695@1|root,COG1695@2|Bacteria,4P442@976|Bacteroidetes,47V9Z@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_1456247_22 1121931.AUHG01000012_gene2607 7.374e-08 62.0 COG2318@1|root,COG2318@2|Bacteria,4NNW4@976|Bacteroidetes,1I28C@117743|Flavobacteriia 976|Bacteroidetes J DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_1456247_14 1408473.JHXO01000011_gene2983 1.108e-43 162.0 COG3070@1|root,COG3070@2|Bacteria,4NQWP@976|Bacteroidetes,2FTFF@200643|Bacteroidia 976|Bacteroidetes K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N CMS3_k127_1456247_7 717231.Flexsi_0218 1.108e-105 357.0 COG0025@1|root,COG0025@2|Bacteria 2|Bacteria P sodium:proton antiporter activity - - 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - Na_H_Exchanger CMS3_k127_1456247_10 471854.Dfer_4276 9.997e-56 199.0 COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes 976|Bacteroidetes S Pfam Activator of Hsp90 ATPase - - - - - - - - - - - - 3-dmu-9_3-mt,AHSA1 CMS3_k127_1456247_16 743722.Sph21_4600 3.542e-41 154.0 COG0640@1|root,COG0640@2|Bacteria,4NSDX@976|Bacteroidetes,1IXV7@117747|Sphingobacteriia 976|Bacteroidetes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 CMS3_k127_1456247_1 886377.Murru_0073 5.637e-224 705.0 COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,1I137@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_1456247_18 37919.EP51_05135 4.053e-32 128.0 2ED24@1|root,336Z2@2|Bacteria,2HJJJ@201174|Actinobacteria,4G6XU@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - CMS3_k127_1456247_0 1296416.JACB01000042_gene1790 1.256e-270 850.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia,2YHQ2@290174|Aquimarina 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_1456247_9 1121904.ARBP01000008_gene3413 2.384e-76 259.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PA8@768503|Cytophagia 976|Bacteroidetes C 2Fe-2S -binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_1456247_21 1356852.N008_09185 3.623e-14 74.0 COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes,47RZY@768503|Cytophagia 976|Bacteroidetes H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS CMS3_k127_1456247_13 1121904.ARBP01000005_gene4463 6.735e-44 164.0 COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,47QJT@768503|Cytophagia 976|Bacteroidetes H Molybdopterin converting factor, large subunit moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE CMS3_k127_1456247_8 373903.Hore_01880 2.22e-77 265.0 COG4912@1|root,COG4912@2|Bacteria,1UYUP@1239|Firmicutes,24ACV@186801|Clostridia 186801|Clostridia L PFAM DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation CMS3_k127_1456247_2 391587.KAOT1_01844 3.577e-207 654.0 COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes,1HX25@117743|Flavobacteriia 976|Bacteroidetes S Peptidase m28 - - - - - - - - - - - - Peptidase_M28,fn3 CMS3_k127_1456247_4 1237149.C900_00839 7.27e-178 588.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_1456247_19 1237149.C900_00248 3.4e-28 116.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_1456247_6 929562.Emtol_0994 5.331e-119 412.0 COG1629@1|root,COG2373@1|root,COG1629@2|Bacteria,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,47K94@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - A2M,A2M_N,A2M_comp,A2M_recep,Plug,Thiol-ester_cl CMS3_k127_1486465_5 1237149.C900_03994 2.4e-48 182.0 2A7CX@1|root,334RT@2|Bacteria,4NVQR@976|Bacteroidetes,47RXJ@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_1486465_3 1237149.C900_03993 4.334e-118 385.0 COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,47JJ9@768503|Cytophagia 976|Bacteroidetes I enoyl-CoA hydratase isomerase family - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 CMS3_k127_1486465_6 1237149.C900_03992 4.634e-33 137.0 COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia 976|Bacteroidetes I phosphoesterase, PA-phosphatase related - - - - - - - - - - - - - CMS3_k127_1486465_1 1237149.C900_03991 4.388e-220 691.0 COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes,47KC2@768503|Cytophagia 976|Bacteroidetes K RNA polymerase, sigma-54 factor rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD CMS3_k127_1486465_0 1120965.AUBV01000005_gene1645 2.605e-231 724.0 COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,47JG8@768503|Cytophagia 976|Bacteroidetes J Asparaginyl-tRNA synthetase asnS - 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon CMS3_k127_1486465_8 620914.JH621249_gene3301 5.674e-08 59.0 COG1874@1|root,COG1874@2|Bacteria,4P0ZW@976|Bacteroidetes 976|Bacteroidetes G Beta-galactosidase - - - - - - - - - - - - Glyco_hydro_42 CMS3_k127_1486465_2 1237149.C900_03983 6.333e-152 495.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,4NG2F@976|Bacteroidetes,47JYX@768503|Cytophagia 976|Bacteroidetes G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N CMS3_k127_1486465_4 1123277.KB893177_gene3622 6.59e-62 219.0 COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,47NJ0@768503|Cytophagia 976|Bacteroidetes S Peptidase S16, lon domain protein - - 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - LON_substr_bdg CMS3_k127_1486465_7 1313301.AUGC01000001_gene1409 2.226e-15 76.0 COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes 976|Bacteroidetes C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS3_k127_1488010_3 1313301.AUGC01000004_gene2230 0.0002091 50.0 COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 CMS3_k127_1488010_2 1250232.JQNJ01000001_gene3386 1.373e-53 195.0 COG0727@1|root,COG0727@2|Bacteria,4NMJ0@976|Bacteroidetes,1I1AF@117743|Flavobacteriia 976|Bacteroidetes S PFAM Uncharacterised protein family (UPF0153) - - - - - - - - - - - - CxxCxxCC CMS3_k127_1488010_1 926549.KI421517_gene3572 1.775e-87 305.0 COG0739@1|root,COG0739@2|Bacteria,4NEBZ@976|Bacteroidetes,47JJ1@768503|Cytophagia 976|Bacteroidetes M Peptidase family M23 - - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23,SH3_3,SH3_4 CMS3_k127_1488010_0 1313421.JHBV01000012_gene4088 9.11e-112 368.0 COG0644@1|root,COG0644@2|Bacteria 2|Bacteria C geranylgeranyl reductase activity - - - - - - - - - - - - FAD_binding_3,Lycopene_cycl,Trp_halogenase CMS3_k127_1514489_9 1237149.C900_01193 9.031e-51 184.0 COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,47KM1@768503|Cytophagia 976|Bacteroidetes D Belongs to the ABC-4 integral membrane protein family. FtsX subfamily ftsX GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX CMS3_k127_1514489_5 1237149.C900_01196 2.737e-87 290.0 COG1595@1|root,COG1595@2|Bacteria,4NX8R@976|Bacteroidetes,47PIG@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_ECF,Sigma70_r2 CMS3_k127_1514489_0 743722.Sph21_2245 0.0 1094.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1IQBM@117747|Sphingobacteriia 976|Bacteroidetes C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA CMS3_k127_1514489_12 1237149.C900_00315 8.399e-44 164.0 COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 CMS3_k127_1514489_3 1237149.C900_00316 4.337e-105 346.0 COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes,47MMS@768503|Cytophagia 976|Bacteroidetes H TIGRFAM GTP cyclohydrolase I folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI CMS3_k127_1514489_8 1239962.C943_02757 1.275e-61 214.0 COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,47PQ5@768503|Cytophagia 976|Bacteroidetes H PFAM 6-pyruvoyl tetrahydropterin synthase ygcM - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS CMS3_k127_1514489_2 344747.PM8797T_04345 4.56e-145 467.0 COG1446@1|root,COG1446@2|Bacteria,2IZ4V@203682|Planctomycetes 203682|Planctomycetes E PFAM peptidase T2 asparaginase 2 - - 3.4.19.5,3.5.1.26 ko:K01444,ko:K13051 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2,DUF4440 CMS3_k127_1514489_6 1237149.C900_04913 5.743e-82 278.0 COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,47SZE@768503|Cytophagia 976|Bacteroidetes T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos CMS3_k127_1514489_7 1124780.ANNU01000012_gene3912 1.261e-61 214.0 28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,47QD1@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0403 family yqiW - - - - - - - - - - - Disulph_isomer CMS3_k127_1514489_11 643867.Ftrac_0912 4.52e-47 172.0 COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,47QBC@768503|Cytophagia 976|Bacteroidetes S FeS assembly SUF system protein yitW - - - - - - - - - - - FeS_assembly_P CMS3_k127_1514489_10 1121904.ARBP01000003_gene6458 1.131e-50 183.0 COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,47Q7A@768503|Cytophagia 976|Bacteroidetes S SufE protein probably involved in Fe-S center assembly sufE - - ko:K02426 - - - - ko00000 - - - SufE CMS3_k127_1514489_1 643867.Ftrac_0910 7.795e-184 582.0 COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,47JNS@768503|Cytophagia 976|Bacteroidetes E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 CMS3_k127_1514489_4 1121904.ARBP01000016_gene5255 1.73e-103 350.0 COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,47K0R@768503|Cytophagia 976|Bacteroidetes O TIGRFAM FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 CMS3_k127_1552396_0 1121896.JMLU01000026_gene681 3.184e-19 103.0 COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia,2NSHK@237|Flavobacterium 976|Bacteroidetes M RHS repeat-associated core domain - - - - - - - - - - - - - CMS3_k127_1552396_1 471854.Dfer_2225 1.061e-12 81.0 COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - SBBP CMS3_k127_1596893_0 1121904.ARBP01000009_gene4264 2.154e-93 327.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1605875_3 742727.HMPREF9447_04273 6.187e-23 100.0 COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,2FTE9@200643|Bacteroidia,4ARNF@815|Bacteroidaceae 976|Bacteroidetes IQ Phosphopantetheine attachment site acpP2 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_1605875_5 746697.Aeqsu_1520 3.301e-06 55.0 28JFU@1|root,2Z99Q@2|Bacteria,4NJ9K@976|Bacteroidetes,1HYW4@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1605875_0 1046627.BZARG_395 1.456e-76 267.0 COG4984@1|root,COG4984@2|Bacteria,4NGMI@976|Bacteroidetes,1I06Q@117743|Flavobacteriia 976|Bacteroidetes S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 CMS3_k127_1605875_1 1046627.BZARG_394 1.175e-74 263.0 28PXB@1|root,2ZCHA@2|Bacteria,4NNEG@976|Bacteroidetes,1I66S@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4401) - - - - - - - - - - - - DUF4401 CMS3_k127_1605875_2 445961.IW15_07990 3.232e-37 145.0 COG4929@1|root,COG4929@2|Bacteria,4NRFH@976|Bacteroidetes,1I3D3@117743|Flavobacteriia,3ZRZ7@59732|Chryseobacterium 976|Bacteroidetes S GDYXXLXY protein - - - - - - - - - - - - GDYXXLXY CMS3_k127_1660974_1 313606.M23134_02050 2.531e-118 392.0 COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_1660974_3 1123368.AUIS01000038_gene37 5.566e-71 246.0 COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,1S4YT@1236|Gammaproteobacteria,2ND78@225057|Acidithiobacillales 225057|Acidithiobacillales S Dienelactone hydrolase family - - - - - - - - - - - - DLH CMS3_k127_1660974_0 313603.FB2170_01836 0.0 1703.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia,2PGS6@252356|Maribacter 976|Bacteroidetes M Tricorn protease C1 domain - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ CMS3_k127_1660974_2 700598.Niako_4080 5.737e-87 292.0 COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,1IT9J@117747|Sphingobacteriia 976|Bacteroidetes U Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP CMS3_k127_1663824_6 1237149.C900_03789 2.947e-90 308.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS3_k127_1663824_7 1237149.C900_03788 5.427e-80 272.0 COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia 976|Bacteroidetes S PFAM O-methyltransferase mdmC - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 CMS3_k127_1663824_1 1124780.ANNU01000075_gene834 2.083e-178 567.0 COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,47JFQ@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_1663824_0 1124780.ANNU01000008_gene2775 2.154e-196 620.0 COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia 976|Bacteroidetes E Belongs to the peptidase M24B family pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 CMS3_k127_1663824_12 1116369.KB890024_gene3076 9.754e-22 100.0 COG0394@1|root,COG1246@1|root,COG0394@2|Bacteria,COG1246@2|Bacteria,1MWYQ@1224|Proteobacteria,2TU1U@28211|Alphaproteobacteria,43NQK@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T Low molecular weight phosphatase family arsC1 - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc CMS3_k127_1663824_10 313606.M23134_00440 4.855e-59 207.0 COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia 976|Bacteroidetes J Endoribonuclease L-PSP - - 3.5.99.5 ko:K15067 ko00380,map00380 - R03887 RC01015 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP CMS3_k127_1663824_3 1237149.C900_00090 1.743e-117 384.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,47M4X@768503|Cytophagia 976|Bacteroidetes J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS CMS3_k127_1663824_2 153721.MYP_98 1.132e-118 385.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,47M3D@768503|Cytophagia 976|Bacteroidetes J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 CMS3_k127_1663824_11 1048983.EL17_06475 3.442e-50 181.0 COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,47Q9B@768503|Cytophagia 976|Bacteroidetes J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 CMS3_k127_1663824_9 1237149.C900_00094 8.389e-66 229.0 COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,47PQ7@768503|Cytophagia 976|Bacteroidetes J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 CMS3_k127_1663824_8 1237149.C900_00095 1.893e-79 271.0 COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,47KJC@768503|Cytophagia 976|Bacteroidetes J TIGRFAM pseudouridine synthase, RluA family - - 5.4.99.23,5.4.99.24 ko:K06179,ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 CMS3_k127_1663824_5 1237149.C900_01144 1.98e-97 329.0 COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,47JX1@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_1663824_4 1124780.ANNU01000043_gene343 1.509e-97 321.0 COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia 976|Bacteroidetes T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS3_k127_1696901_3 1237149.C900_04024 2.552e-52 189.0 COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Outer membrane assembly lipoprotein YfiO yfiO - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO CMS3_k127_1696901_2 1237149.C900_04025 1.435e-63 226.0 2AEI8@1|root,331SH@2|Bacteria,4NWWM@976|Bacteroidetes,47S6K@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1696901_0 1237149.C900_04026 1.168e-161 524.0 COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,47KAE@768503|Cytophagia 976|Bacteroidetes M OstA-like protein - - - - - - - - - - - - OstA,OstA_2 CMS3_k127_1696901_1 1354314.CHV_b0013 9.241e-81 283.0 COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,47M2U@768503|Cytophagia 976|Bacteroidetes D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS_C CMS3_k127_1722314_10 515635.Dtur_1285 1.584e-13 83.0 COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - PPC,Peptidase_M8,Peptidase_S8,SLH CMS3_k127_1722314_8 1121373.KB903632_gene414 1.712e-39 161.0 2E0MA@1|root,32W6I@2|Bacteria,4NNWD@976|Bacteroidetes,47Q2K@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_1722314_0 1237149.C900_05107 0.0 1071.0 COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes,47NKP@768503|Cytophagia 976|Bacteroidetes M WD40 repeats - - - - - - - - - - - - WD40 CMS3_k127_1722314_1 1237149.C900_05108 0.0 1040.0 COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia 976|Bacteroidetes C - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - HEAT_2,cNMP_binding CMS3_k127_1722314_5 1237149.C900_01582 2.014e-63 230.0 COG0457@1|root,COG0457@2|Bacteria 1237149.C900_01582|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - CMS3_k127_1722314_3 1237149.C900_01581 3.189e-113 371.0 COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,47MT6@768503|Cytophagia 976|Bacteroidetes O PFAM SPFH domain Band 7 family - - - - - - - - - - - - Band_7 CMS3_k127_1722314_2 1237149.C900_01580 1.35e-217 681.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia 976|Bacteroidetes C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt CMS3_k127_1722314_9 643867.Ftrac_0876 5.385e-24 104.0 COG4281@1|root,COG4281@2|Bacteria,4NVK0@976|Bacteroidetes,47RZ1@768503|Cytophagia 976|Bacteroidetes I Acyl CoA binding protein - - - - - - - - - - - - ACBP CMS3_k127_1722314_6 1237149.C900_01578 1.157e-54 199.0 COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,47PRE@768503|Cytophagia 976|Bacteroidetes J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA CMS3_k127_1722314_4 1237149.C900_01576 3.358e-102 335.0 COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,47JSE@768503|Cytophagia 976|Bacteroidetes S PFAM Nucleoside recognition spmA - - ko:K06373 - - - - ko00000 - - - Gate CMS3_k127_1730560_2 1150600.ADIARSV_3322 2.359e-179 588.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ0T@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1730560_6 1121904.ARBP01000012_gene1244 9.471e-69 246.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1730560_7 760192.Halhy_2972 2.38e-62 229.0 COG5337@1|root,COG5337@2|Bacteria,4P3EE@976|Bacteroidetes 976|Bacteroidetes M CotH kinase protein - - - ko:K06330 - - - - ko00000 - - - CotH CMS3_k127_1730560_9 1048983.EL17_10520 2.838e-22 108.0 COG4403@1|root,COG4403@2|Bacteria,4PKR3@976|Bacteroidetes,47QES@768503|Cytophagia 976|Bacteroidetes V Lanthionine synthetase C family protein - - - - - - - - - - - - - CMS3_k127_1730560_8 1121904.ARBP01000004_gene1023 1.499e-32 129.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 2|Bacteria K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_1730560_1 760192.Halhy_2192 1.491e-181 599.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IPB0@117747|Sphingobacteriia 976|Bacteroidetes V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1730560_0 1123278.KB893589_gene495 0.0 1065.0 COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47MAT@768503|Cytophagia 976|Bacteroidetes CG Cytochrome c, class I - - - ko:K08738,ko:K09992 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA CMS3_k127_1730560_4 1122137.AQXF01000004_gene1524 1.725e-164 526.0 COG0477@1|root,COG2814@2|Bacteria,1QWEI@1224|Proteobacteria,2U6BP@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Nucleoside H+ symporter - - - - - - - - - - - - Nuc_H_symport CMS3_k127_1730560_3 700598.Niako_2203 1.169e-174 556.0 COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_1730560_5 643867.Ftrac_3686 1.148e-141 462.0 COG2010@1|root,COG2010@2|Bacteria,4NF0A@976|Bacteroidetes,47J8Z@768503|Cytophagia 976|Bacteroidetes C PFAM Class III cytochrome C family actA - - - - - - - - - - - Cytochrom_C,Cytochrom_CIII,Cytochrome_C7 CMS3_k127_1730560_10 1120968.AUBX01000014_gene2322 8.111e-08 53.0 COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain nrfC - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molydop_binding CMS3_k127_1739078_5 1313301.AUGC01000005_gene329 5.825e-06 50.0 COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes 976|Bacteroidetes NU tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8 CMS3_k127_1739078_1 1122176.KB903531_gene2809 2.045e-90 306.0 COG0412@1|root,COG0412@2|Bacteria,4NKMA@976|Bacteroidetes,1IV93@117747|Sphingobacteriia 976|Bacteroidetes Q BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DLH CMS3_k127_1739078_3 1408473.JHXO01000009_gene3256 7.753e-35 138.0 COG4319@1|root,COG4319@2|Bacteria,4NSIN@976|Bacteroidetes 976|Bacteroidetes S ketosteroid isomerase - - - - - - - - - - - - DUF4440 CMS3_k127_1739078_0 1124780.ANNU01000078_gene757 1.5e-277 876.0 COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,47JEM@768503|Cytophagia 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_1739078_4 1121904.ARBP01000017_gene5134 4.675e-26 110.0 COG1695@1|root,COG1695@2|Bacteria,4P6G7@976|Bacteroidetes,47VZ7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_1739078_2 1237149.C900_03947 1.383e-58 217.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1751973_1 316274.Haur_3711 9.406e-52 196.0 COG4641@1|root,COG4641@2|Bacteria 2|Bacteria M Protein conserved in bacteria - - - ko:K06320 - - - - ko00000 - - - DUF3880,Glyco_trans_1_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 CMS3_k127_1751973_0 643867.Ftrac_2414 1.57e-117 392.0 28ICP@1|root,2Z8EZ@2|Bacteria,4NKKI@976|Bacteroidetes,47N2N@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1751973_2 1121859.KB890739_gene2391 5.503e-30 124.0 COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,47Y4H@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 CMS3_k127_1755927_3 1124780.ANNU01000033_gene1310 1.149e-111 375.0 COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,47NKF@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_1755927_0 1408473.JHXO01000013_gene608 0.0 1835.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2G0EK@200643|Bacteroidia 976|Bacteroidetes V AcrB/AcrD/AcrF family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran CMS3_k127_1755927_7 880070.Cycma_4601 1.853e-22 102.0 2DSGB@1|root,33G1A@2|Bacteria,4NZ4A@976|Bacteroidetes,47V5I@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1755927_2 313606.M23134_06918 1.181e-176 562.0 COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47JWT@768503|Cytophagia 976|Bacteroidetes S integral membrane protein - - - - - - - - - - - - DUF819 CMS3_k127_1755927_4 324602.Caur_1131 1.762e-101 351.0 COG2866@1|root,COG2866@2|Bacteria,2G7PS@200795|Chloroflexi,376WU@32061|Chloroflexia 32061|Chloroflexia E PFAM peptidase M14, carboxypeptidase A - - - - - - - - - - - - Peptidase_M14 CMS3_k127_1755927_1 1237149.C900_01529 2.162e-268 848.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_1755927_5 929562.Emtol_0833 2.53e-94 319.0 COG2367@1|root,COG2367@2|Bacteria,4PMKC@976|Bacteroidetes,47JSP@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 CMS3_k127_1755927_6 1279009.ADICEAN_03262 1.17e-28 119.0 2E6VI@1|root,331F4@2|Bacteria,4NWUI@976|Bacteroidetes,47T84@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1755927_9 1392488.JHZY01000004_gene3519 6.571e-08 61.0 2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,1I2EY@117743|Flavobacteriia,2XJEQ@283735|Leeuwenhoekiella 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1755927_8 565045.NOR51B_2828 2.688e-14 74.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria 1236|Gammaproteobacteria S amidohydrolase hipO - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_1847588_2 388413.ALPR1_00675 1.45e-166 543.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase CMS3_k127_1847588_5 903814.ELI_3666 3.533e-33 134.0 COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia,25W3H@186806|Eubacteriaceae 186801|Clostridia S Aminoacyl-tRNA editing domain proX - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit CMS3_k127_1847588_0 1047013.AQSP01000134_gene1353 1.716e-284 902.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_1847588_3 1121104.AQXH01000001_gene1951 4.696e-120 398.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - - - - - - - - - - Amidohydro_1 CMS3_k127_1847588_1 1237149.C900_04385 1.585e-175 556.0 COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,47J9X@768503|Cytophagia 976|Bacteroidetes C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C CMS3_k127_1847588_4 1237149.C900_04383 4.418e-102 340.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,47KBE@768503|Cytophagia 976|Bacteroidetes M Tetratricopeptide repeat protein - - - - - - - - - - - - OmpA,TPR_16,TPR_2,TPR_8 CMS3_k127_1878004_3 313606.M23134_08314 7.116e-59 210.0 COG1595@1|root,COG1595@2|Bacteria,4NU4K@976|Bacteroidetes,47UQA@768503|Cytophagia 976|Bacteroidetes K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_1878004_2 1237149.C900_05603 1.237e-103 343.0 COG0500@1|root,COG2226@2|Bacteria,4NE6P@976|Bacteroidetes,47K6K@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase domain rebM - - - - - - - - - - - Methyltransf_11 CMS3_k127_1878004_1 269798.CHU_1791 1.825e-114 377.0 COG1215@1|root,COG1215@2|Bacteria,4PKBU@976|Bacteroidetes,47MX1@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_trans_2_3,Glycos_transf_2 CMS3_k127_1878004_0 1237149.C900_05601 7.05e-130 421.0 COG1215@1|root,COG1215@2|Bacteria,4PKF3@976|Bacteroidetes,47XY0@768503|Cytophagia 976|Bacteroidetes M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_1878004_4 1237149.C900_05600 4.397e-18 86.0 2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,47QS1@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 CMS3_k127_19376_2 1121904.ARBP01000002_gene6689 6.143e-123 431.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes 2|Bacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - CHAT,TPR_12,TPR_16,TPR_7,TPR_8 CMS3_k127_19376_9 1499967.BAYZ01000156_gene556 1.166e-61 219.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.222,2.1.1.64 ko:K00568,ko:K20444 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 CMS3_k127_19376_5 1296416.JACB01000043_gene1851 1.892e-108 361.0 COG0460@1|root,COG0460@2|Bacteria,4NHRC@976|Bacteroidetes,1HZK9@117743|Flavobacteriia,2YKHN@290174|Aquimarina 976|Bacteroidetes E Homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 CMS3_k127_19376_8 76114.ebA6209 3.734e-66 229.0 COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2WA5A@28216|Betaproteobacteria,2KXNR@206389|Rhodocyclales 206389|Rhodocyclales J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 CMS3_k127_19376_0 1237149.C900_00798 5.73e-256 812.0 COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,47JKP@768503|Cytophagia 976|Bacteroidetes M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,6.3.2.10 ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 - R00401,R04573,R04617 RC00064,RC00141,RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M CMS3_k127_19376_7 1237149.C900_00799 6.131e-76 264.0 COG0454@1|root,COG0456@2|Bacteria,4NKGU@976|Bacteroidetes 976|Bacteroidetes K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 CMS3_k127_19376_11 1121930.AQXG01000001_gene1371 1.199e-43 161.0 COG0073@1|root,COG0073@2|Bacteria,4NQ9I@976|Bacteroidetes 976|Bacteroidetes J tRNA-binding protein csaA - - ko:K06878 - - - - ko00000 - - - tRNA_bind CMS3_k127_19376_3 1237149.C900_00804 7.725e-117 379.0 COG0106@1|root,COG0106@2|Bacteria,4NK0E@976|Bacteroidetes,47NT9@768503|Cytophagia 976|Bacteroidetes E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase - - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS3_k127_19376_6 761193.Runsl_2215 3.164e-86 290.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,47KCE@768503|Cytophagia 976|Bacteroidetes T PFAM response regulator receiver rprY - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_19376_4 1124780.ANNU01000048_gene2161 3.174e-111 376.0 COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_19376_1 1237149.C900_00811 1.429e-199 628.0 COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,47JBT@768503|Cytophagia 976|Bacteroidetes E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CMS3_k127_19376_10 1313421.JHBV01000052_gene192 5.692e-49 183.0 COG3209@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5384@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5384@2|Bacteria,4PPW2@976|Bacteroidetes,1J12N@117747|Sphingobacteriia 2|Bacteria JMU domain protein - - 3.2.1.4 ko:K01179,ko:K19360,ko:K21449 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko02000,ko03036 1.B.40.2 GH5,GH9 - FIVAR,LRR_5,Phospholip_A2_3 CMS3_k127_1962297_0 1237149.C900_03423 1.897e-231 742.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2,TPR_21,TPR_6,TPR_8 CMS3_k127_1962297_1 1237149.C900_03422 4.615e-109 373.0 COG4206@1|root,COG4206@2|Bacteria,4NGYD@976|Bacteroidetes,47JSU@768503|Cytophagia 976|Bacteroidetes H Psort location OuterMembrane, score - - - - - - - - - - - - TonB_dep_Rec CMS3_k127_1962297_5 1237149.C900_03421 2.371e-48 182.0 COG3087@1|root,COG3087@2|Bacteria,4NVU5@976|Bacteroidetes,47S99@768503|Cytophagia 976|Bacteroidetes D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - SPOR CMS3_k127_1962297_2 1124780.ANNU01000025_gene3403 7.25e-101 333.0 COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,47N0M@768503|Cytophagia 976|Bacteroidetes U PFAM MotA TolQ ExbB proton channel exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB CMS3_k127_1962297_4 643867.Ftrac_0328 5.426e-50 180.0 COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,47R2X@768503|Cytophagia 976|Bacteroidetes U Biopolymer transport protein ExbD TolR exbD - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD CMS3_k127_1962297_6 1237149.C900_03418 2.207e-47 181.0 COG3170@1|root,COG3170@2|Bacteria,4PKQP@976|Bacteroidetes,47JDN@768503|Cytophagia 976|Bacteroidetes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - CMS3_k127_1962297_3 1120965.AUBV01000007_gene2500 3.457e-69 238.0 COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,47K0F@768503|Cytophagia 976|Bacteroidetes H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M CMS3_k127_198611_7 880073.Calab_3195 3.592e-114 380.0 COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria 2|Bacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K04487,ko:K11717 ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122 - R03599,R07460,R11528,R11529 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CMS3_k127_198611_12 518766.Rmar_2771 1.134e-41 162.0 COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes 976|Bacteroidetes S MobA-related protein - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 CMS3_k127_198611_16 765420.OSCT_2308 0.0001208 53.0 COG2105@1|root,COG2105@2|Bacteria,2G9XK@200795|Chloroflexi,377R8@32061|Chloroflexia 32061|Chloroflexia S PFAM AIG2 family protein - - - - - - - - - - - - GGACT CMS3_k127_198611_9 468059.AUHA01000002_gene938 3.69e-62 224.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,1IPA5@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_198611_3 580340.Tlie_1160 5.697e-138 449.0 COG0520@1|root,COG0520@2|Bacteria,3TAAX@508458|Synergistetes 508458|Synergistetes E TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - - - - - - - - - - Aminotran_5 CMS3_k127_198611_1 1408433.JHXV01000001_gene821 1.08e-191 612.0 COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,1IITP@117743|Flavobacteriia,2PBDU@246874|Cryomorphaceae 976|Bacteroidetes Q Flavin containing amine oxidoreductase - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,NAD_binding_8 CMS3_k127_198611_11 1237149.C900_02076 8.89e-49 180.0 COG1416@1|root,COG1416@2|Bacteria,4NQQE@976|Bacteroidetes,47YKC@768503|Cytophagia 976|Bacteroidetes S DsrE/DsrF-like family - - - - - - - - - - - - DrsE CMS3_k127_198611_15 1123008.KB905697_gene3328 3.643e-13 71.0 2BF9Z@1|root,3292V@2|Bacteria,4P6RX@976|Bacteroidetes,2FZNS@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_198611_14 1189612.A33Q_1729 3.07e-18 85.0 COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,47S1G@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Arc,RHH_5 CMS3_k127_198611_4 1121904.ARBP01000020_gene2818 1.249e-125 407.0 COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia 976|Bacteroidetes O membrane protease - - - - - - - - - - - - Band_7 CMS3_k127_198611_6 1123278.KB893623_gene3429 1.281e-122 409.0 COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_198611_5 643867.Ftrac_1699 1.208e-122 399.0 COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,47K35@768503|Cytophagia 976|Bacteroidetes S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 CMS3_k127_198611_0 760192.Halhy_1321 2.337e-263 827.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1IVS2@117747|Sphingobacteriia 976|Bacteroidetes EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_198611_8 1121904.ARBP01000003_gene6153 5.847e-108 358.0 COG0667@1|root,COG0667@2|Bacteria,4NHAU@976|Bacteroidetes,47NRK@768503|Cytophagia 976|Bacteroidetes C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CMS3_k127_198611_2 1122176.KB903532_gene2712 3.85e-143 462.0 COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,1ISEJ@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - DUF5001,PHP CMS3_k127_198611_13 498211.CJA_2991 2.036e-22 109.0 COG2207@1|root,COG2207@2|Bacteria,1NVER@1224|Proteobacteria,1RQWM@1236|Gammaproteobacteria,1FGF1@10|Cellvibrio 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - Arabinose_bd,HTH_18 CMS3_k127_198611_10 118161.KB235922_gene2880 1.721e-60 232.0 COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,3VHWS@52604|Pleurocapsales 1117|Cyanobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_198611_17 398512.JQKC01000009_gene559 0.0002405 44.0 COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes 1239|Firmicutes L Exonuclease yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 CMS3_k127_1990130_14 1041138.KB890225_gene6213 0.0008684 44.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase cyaF2 - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,TPR_16,TPR_19,TPR_2,TPR_8 CMS3_k127_1990130_13 1120965.AUBV01000001_gene3459 2.935e-23 109.0 2DP33@1|root,330AX@2|Bacteria,4NX23@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1990130_1 1237149.C900_02538 1.172e-173 566.0 COG0508@1|root,COG0508@2|Bacteria,4PKNP@976|Bacteroidetes,47MW8@768503|Cytophagia 976|Bacteroidetes C Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 CMS3_k127_1990130_10 1237149.C900_02539 1.639e-73 252.0 COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,47M9N@768503|Cytophagia 976|Bacteroidetes K Belongs to the UPF0301 (AlgH) family - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 CMS3_k127_1990130_8 1237149.C900_02540 2.828e-81 274.0 COG4445@1|root,COG4445@2|Bacteria,4NP3S@976|Bacteroidetes,47Q34@768503|Cytophagia 976|Bacteroidetes FJ tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) - - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE CMS3_k127_1990130_9 1237149.C900_02541 2.388e-75 259.0 COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,47P7A@768503|Cytophagia 976|Bacteroidetes H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx CMS3_k127_1990130_5 1237149.C900_02542 2.768e-97 331.0 COG1215@1|root,COG1215@2|Bacteria,4NMSY@976|Bacteroidetes,47NMB@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_1990130_6 1120968.AUBX01000009_gene451 1.31e-95 318.0 COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47K51@768503|Cytophagia 976|Bacteroidetes S PFAM GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L CMS3_k127_1990130_3 1237149.C900_04237 2.376e-160 509.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,47JQX@768503|Cytophagia 976|Bacteroidetes C Thioredoxin reductase trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS3_k127_1990130_2 1237149.C900_04236 8.575e-167 526.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS3_k127_1990130_0 1237149.C900_04235 4.985e-313 973.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,47KTE@768503|Cytophagia 976|Bacteroidetes J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 CMS3_k127_1990130_12 1120966.AUBU01000010_gene2718 2.806e-36 138.0 COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,47R7H@768503|Cytophagia 976|Bacteroidetes J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 CMS3_k127_1990130_4 1237149.C900_04233 2.082e-158 516.0 COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,47JCU@768503|Cytophagia 976|Bacteroidetes S Permease YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ CMS3_k127_1990130_11 643867.Ftrac_0683 1.398e-46 171.0 COG3832@1|root,COG3832@2|Bacteria,4NNY1@976|Bacteroidetes,47R94@768503|Cytophagia 976|Bacteroidetes S Pfam Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 CMS3_k127_1990130_7 929556.Solca_4215 6.854e-93 308.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,1IPW9@117747|Sphingobacteriia 976|Bacteroidetes J elongation factor G domain IV fusA2 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CMS3_k127_2035481_3 1123278.KB893554_gene3964 1.877e-39 149.0 COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia 976|Bacteroidetes I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom CMS3_k127_2035481_0 1237149.C900_01115 3.122e-240 750.0 COG0318@1|root,COG0318@2|Bacteria,4NDYR@976|Bacteroidetes,47JUW@768503|Cytophagia 976|Bacteroidetes IQ PFAM GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 CMS3_k127_2035481_2 886377.Murru_1686 1.903e-54 203.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - Abhydrolase_6,DLH CMS3_k127_2035481_1 929562.Emtol_1304 1.78e-152 486.0 COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,47K03@768503|Cytophagia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA,Succ_CoA_lig CMS3_k127_2064589_55 1492737.FEM08_14010 1.216e-06 50.0 COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia,2NSAS@237|Flavobacterium 976|Bacteroidetes C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A CMS3_k127_2064589_50 1168034.FH5T_08920 7.743e-21 94.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C CMS3_k127_2064589_39 926549.KI421517_gene2268 1.558e-44 166.0 COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,47Q9K@768503|Cytophagia 976|Bacteroidetes C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B CMS3_k127_2064589_36 1237149.C900_04604 2.761e-53 192.0 COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP CMS3_k127_2064589_2 1237149.C900_04605 6.102e-281 869.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,47JFI@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N CMS3_k127_2064589_15 926556.Echvi_0607 6.075e-111 365.0 COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,47JM0@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt CMS3_k127_2064589_47 1279009.ADICEAN_02902 1.602e-27 122.0 2DBER@1|root,2Z8TN@2|Bacteria,4NK2P@976|Bacteroidetes,47P45@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2064589_43 471854.Dfer_2850 5.574e-36 146.0 COG0500@1|root,COG2226@2|Bacteria,4NSPB@976|Bacteroidetes,47RD0@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_12,Methyltransf_2,Methyltransf_25 CMS3_k127_2064589_19 1121904.ARBP01000013_gene453 6.629e-108 365.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2 CMS3_k127_2064589_38 313606.M23134_04763 6.298e-51 184.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,47QVZ@768503|Cytophagia 976|Bacteroidetes O OsmC-like protein - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC CMS3_k127_2064589_7 1237149.C900_00365 2.534e-175 557.0 COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia 976|Bacteroidetes K Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - CMS3_k127_2064589_41 1237149.C900_00366 6.495e-38 149.0 COG1238@1|root,COG1238@2|Bacteria,4NMW6@976|Bacteroidetes,47VDA@768503|Cytophagia 976|Bacteroidetes I metal cluster binding - - - - - - - - - - - - SNARE_assoc CMS3_k127_2064589_9 1237149.C900_00369 3.348e-169 538.0 COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,47MAZ@768503|Cytophagia 976|Bacteroidetes E PFAM aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CMS3_k127_2064589_10 1189612.A33Q_2548 3.467e-168 540.0 COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,47KR9@768503|Cytophagia 976|Bacteroidetes G Phosphoglucomutase phosphomannomutase alpha beta alpha domain I glmM - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS3_k127_2064589_49 1237149.C900_00372 1.021e-23 101.0 2E5GR@1|root,3308C@2|Bacteria,4NUPC@976|Bacteroidetes,47S69@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2064589_17 1279009.ADICEAN_00625 5.612e-110 361.0 COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,47K4M@768503|Cytophagia 976|Bacteroidetes S PFAM MazG nucleotide pyrophosphohydrolase mazG - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - MazG CMS3_k127_2064589_6 1121904.ARBP01000012_gene1293 1.04e-194 626.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria 2|Bacteria P domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N CMS3_k127_2064589_3 1237149.C900_00375 4.139e-255 794.0 COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,47MCS@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family glyQS - 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b CMS3_k127_2064589_30 1279009.ADICEAN_00647 6.875e-75 259.0 COG3228@1|root,COG3228@2|Bacteria,4NMII@976|Bacteroidetes,47QA7@768503|Cytophagia 976|Bacteroidetes S Glucose-regulated metallo-peptidase M90 - - - ko:K09933 - - - - ko00000,ko01002 - - - Peptidase_M90 CMS3_k127_2064589_12 1237149.C900_03148 2.421e-166 534.0 COG0232@1|root,COG0232@2|Bacteria,4NENM@976|Bacteroidetes,47KD3@768503|Cytophagia 976|Bacteroidetes F Deoxyguanosinetriphosphate triphosphohydrolase-like protein dgt - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc CMS3_k127_2064589_1 1237149.C900_03147 4.802e-319 995.0 COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia 976|Bacteroidetes S COGs COG1033 exporter of the RND superfamily protein - - - ko:K07003 - - - - ko00000 - - - MMPL CMS3_k127_2064589_0 1237149.C900_03146 0.0 1625.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia 976|Bacteroidetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 CMS3_k127_2064589_24 643867.Ftrac_2466 3.967e-92 307.0 COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia 976|Bacteroidetes M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 CMS3_k127_2064589_48 1124780.ANNU01000006_gene2887 4.475e-26 110.0 COG5512@1|root,COG5512@2|Bacteria,4NXIK@976|Bacteroidetes,47S8C@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 CMS3_k127_2064589_14 926556.Echvi_1156 5.784e-113 375.0 COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,47JMB@768503|Cytophagia 976|Bacteroidetes L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_15,SMC_N CMS3_k127_2064589_11 1189612.A33Q_4275 2.653e-167 531.0 COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,47M0Z@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh CMS3_k127_2064589_31 1237149.C900_04663 2.161e-74 256.0 COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,47PPQ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_21,TPR_6,TPR_7,TPR_8 CMS3_k127_2064589_33 1237149.C900_04662 6.222e-69 238.0 COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,47PCJ@768503|Cytophagia 976|Bacteroidetes H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase CMS3_k127_2064589_4 1237149.C900_01718 3.095e-219 690.0 COG1055@1|root,COG1055@2|Bacteria,4NGWD@976|Bacteroidetes,47KPC@768503|Cytophagia 976|Bacteroidetes P Citrate transporter - - - - - - - - - - - - CitMHS_2 CMS3_k127_2064589_18 1237149.C900_01721 2.088e-108 361.0 COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia 976|Bacteroidetes O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK CMS3_k127_2064589_35 1237149.C900_01722 5.82e-54 198.0 COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K36@768503|Cytophagia 976|Bacteroidetes H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase CMS3_k127_2064589_23 1237149.C900_01723 2.24e-94 324.0 COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,47N37@768503|Cytophagia 976|Bacteroidetes I membrane - - - - - - - - - - - - - CMS3_k127_2064589_22 1124780.ANNU01000006_gene2874 3.721e-98 336.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,47MJ6@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_8 CMS3_k127_2064589_42 641524.ADICYQ_4941 6.349e-37 146.0 COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes,47R6J@768503|Cytophagia 976|Bacteroidetes S Lipopolysaccharide-assembly, LptC-related - - - - - - - - - - - - LptC CMS3_k127_2064589_8 1237149.C900_01726 1.693e-173 553.0 COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,47KQX@768503|Cytophagia 976|Bacteroidetes S CBS domain tlyC - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 CMS3_k127_2064589_5 643867.Ftrac_2006 7.339e-198 638.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,47KBN@768503|Cytophagia 976|Bacteroidetes O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_2 CMS3_k127_2064589_51 1121859.KB890738_gene3589 4.149e-20 92.0 COG2921@1|root,COG2921@2|Bacteria 2|Bacteria S Belongs to the UPF0250 family ybeD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K09158 - - - - ko00000 - - - DUF493 CMS3_k127_2064589_37 1237149.C900_01729 3.399e-53 195.0 COG0500@1|root,COG0500@2|Bacteria,4NPKT@976|Bacteroidetes 976|Bacteroidetes Q Protein of unknown function (DUF1698) - - - - - - - - - - - - Methyltransf_11,Methyltransf_31 CMS3_k127_2064589_45 1123276.KB893266_gene4475 3.537e-30 122.0 COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,47RW0@768503|Cytophagia 976|Bacteroidetes H PFAM Pterin 4 alpha carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a CMS3_k127_2064589_25 761193.Runsl_5534 4.156e-92 307.0 COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,47JDW@768503|Cytophagia 976|Bacteroidetes H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase CMS3_k127_2064589_44 468059.AUHA01000007_gene2681 1.793e-32 131.0 COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1IT7T@117747|Sphingobacteriia 976|Bacteroidetes O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS3_k127_2064589_40 643867.Ftrac_0166 7.06e-40 158.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,47XGI@768503|Cytophagia 976|Bacteroidetes T Universal stress protein family - - - - - - - - - - - - Usp CMS3_k127_2064589_29 865937.Gilli_0341 2.269e-79 278.0 COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,1HYJ8@117743|Flavobacteriia,2P6DA@244698|Gillisia 976|Bacteroidetes K Restriction endonuclease - - - - - - - - - - - - ATP-cone,Mrr_cat CMS3_k127_2064589_46 1237149.C900_02499 3.083e-28 118.0 COG1846@1|root,COG1846@2|Bacteria,4NQDH@976|Bacteroidetes,47QST@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 CMS3_k127_2064589_28 1237149.C900_02500 5.75e-80 271.0 COG2085@1|root,COG2085@2|Bacteria,4NQ1G@976|Bacteroidetes,47Q30@768503|Cytophagia 976|Bacteroidetes S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored CMS3_k127_2064589_26 1121930.AQXG01000017_gene3137 1.588e-86 292.0 COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,1IWMK@117747|Sphingobacteriia 976|Bacteroidetes M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like CMS3_k127_2064589_16 1121930.AQXG01000017_gene3135 3.454e-110 369.0 COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes 976|Bacteroidetes M FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_2064589_27 1313421.JHBV01000042_gene3354 2.024e-84 294.0 COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1IVIT@117747|Sphingobacteriia 976|Bacteroidetes M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_2064589_20 313606.M23134_01607 4.419e-101 333.0 COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,47TWR@768503|Cytophagia 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_2064589_21 1121904.ARBP01000002_gene6765 1.646e-98 335.0 2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2064589_13 1123277.KB893206_gene3393 1.086e-119 411.0 COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47K1N@768503|Cytophagia 976|Bacteroidetes M COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40 CMS3_k127_2064589_32 643867.Ftrac_1238 3.174e-72 254.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,47KE6@768503|Cytophagia 976|Bacteroidetes M TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF CMS3_k127_2064589_52 1202532.FF52_04535 2.221e-14 87.0 COG1361@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - CHU_C,DUF11,SprB CMS3_k127_2064589_34 485918.Cpin_3622 5.638e-65 250.0 COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia 976|Bacteroidetes M conserved repeat domain protein - - - - - - - - - - - - CHU_C,Calx-beta,DUF11,SprB CMS3_k127_2064589_54 1123242.JH636434_gene3785 5.619e-12 79.0 COG2931@1|root,COG2931@2|Bacteria 2|Bacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - An_peroxidase,HemolysinCabind,PD40 CMS3_k127_2066914_3 700598.Niako_4818 4.441e-110 367.0 COG2072@1|root,COG2072@2|Bacteria,4NGC0@976|Bacteroidetes,1IXN7@117747|Sphingobacteriia 976|Bacteroidetes C Flavin-binding monooxygenase-like - - 1.14.13.168 ko:K11816 ko00380,ko01100,map00380,map01100 - R10181 RC00866 ko00000,ko00001,ko01000 - - - FMO-like,Pyr_redox_3 CMS3_k127_2066914_5 1410653.JHVC01000021_gene1281 2.381e-62 225.0 COG1404@1|root,COG1404@2|Bacteria,1UFB1@1239|Firmicutes,24DCR@186801|Clostridia,36H0Y@31979|Clostridiaceae 186801|Clostridia O Belongs to the peptidase S8 family - - - - - - - - - - - - Peptidase_S8 CMS3_k127_2066914_0 1121875.KB907550_gene622 0.0 1494.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia 976|Bacteroidetes M Tricorn protease homolog - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ CMS3_k127_2066914_2 1254432.SCE1572_01320 5.107e-115 379.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42QBD@68525|delta/epsilon subdivisions,2WM4P@28221|Deltaproteobacteria,2YZSV@29|Myxococcales 28221|Deltaproteobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 CMS3_k127_2066914_4 1274524.BSONL12_12806 2.251e-78 282.0 COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4HB23@91061|Bacilli,1ZCVJ@1386|Bacillus 91061|Bacilli E gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS3_k127_2066914_1 760192.Halhy_5259 1.175e-265 826.0 COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - CMS3_k127_2112103_33 411154.GFO_3002 1.652e-42 160.0 COG1228@1|root,COG1228@2|Bacteria,4NGGD@976|Bacteroidetes,1I07B@117743|Flavobacteriia 976|Bacteroidetes Q amidohydrolase - - - - - - - - - - - - Amidohydro_1,SnoaL_2 CMS3_k127_2112103_34 1123073.KB899242_gene1192 1.158e-38 151.0 2DPQD@1|root,332Z4@2|Bacteria,1R3FS@1224|Proteobacteria,1T67D@1236|Gammaproteobacteria,1X7FX@135614|Xanthomonadales 1224|Proteobacteria S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_2112103_2 1123073.KB899241_gene3087 1.313e-264 824.0 COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,1X4F1@135614|Xanthomonadales 135614|Xanthomonadales E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N CMS3_k127_2112103_21 760192.Halhy_3759 9.405e-107 351.0 2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,1INP8@117747|Sphingobacteriia 976|Bacteroidetes S Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_2112103_37 401053.AciPR4_0236 6.643e-20 104.0 COG0412@1|root,COG0412@2|Bacteria,3Y7E5@57723|Acidobacteria 57723|Acidobacteria Q Dienelactone hydrolase - - - - - - - - - - - - - CMS3_k127_2112103_35 313594.PI23P_08110 8.876e-29 117.0 COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia,3VXBM@52959|Polaribacter 976|Bacteroidetes O C-terminal domain of 1-Cys peroxiredoxin - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA CMS3_k127_2112103_39 1349785.BAUG01000045_gene2272 9.461e-11 62.0 COG0450@1|root,COG0450@2|Bacteria,4NEZZ@976|Bacteroidetes,1I036@117743|Flavobacteriia 976|Bacteroidetes O PFAM C-terminal domain of 1-Cys peroxiredoxin - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA CMS3_k127_2112103_7 866536.Belba_1137 1.757e-175 558.0 COG0477@1|root,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,47KR8@768503|Cytophagia 976|Bacteroidetes EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_2112103_13 1121875.KB907547_gene3045 2.715e-146 487.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia 976|Bacteroidetes EU peptidase - - - - - - - - - - - - FGE-sulfatase,PD40,Peptidase_S9 CMS3_k127_2112103_17 313606.M23134_07914 5.143e-117 379.0 COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47KDC@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_2112103_6 929562.Emtol_2888 3.783e-179 571.0 COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,47M24@768503|Cytophagia 976|Bacteroidetes C PFAM Acetyl-CoA hydrolase transferase cat2 - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro CMS3_k127_2112103_27 1237149.C900_02771 3.921e-69 239.0 COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,47PV2@768503|Cytophagia 976|Bacteroidetes O PFAM Scaffold protein Nfu NifU N terminal - - - - - - - - - - - - Nfu_N,NifU CMS3_k127_2112103_14 1286632.P278_11690 1.131e-144 470.0 COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1HYNS@117743|Flavobacteriia 976|Bacteroidetes C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - - - - - - - - - - SDF CMS3_k127_2112103_11 1237149.C900_02769 4.036e-159 508.0 COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia 976|Bacteroidetes E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt CMS3_k127_2112103_9 1237149.C900_02768 2.152e-171 550.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia 976|Bacteroidetes S Oxygen tolerance - - - - - - - - - - - - BatD CMS3_k127_2112103_38 1185876.BN8_06325 4.777e-18 85.0 2A7GX@1|root,30WEH@2|Bacteria,4P9UT@976|Bacteroidetes,47S3Y@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2112103_16 1185876.BN8_04147 6.513e-125 411.0 COG1600@1|root,COG1600@2|Bacteria,4NFCJ@976|Bacteroidetes,47JAQ@768503|Cytophagia 976|Bacteroidetes C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 CMS3_k127_2112103_18 1167006.UWK_02391 2.173e-116 384.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2MI8N@213118|Desulfobacterales 28221|Deltaproteobacteria P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA CMS3_k127_2112103_5 1237149.C900_02766 5.585e-181 570.0 COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,47M82@768503|Cytophagia 976|Bacteroidetes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N CMS3_k127_2112103_24 1237149.C900_02765 4.273e-99 334.0 COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,47N34@768503|Cytophagia 976|Bacteroidetes H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE CMS3_k127_2112103_32 1237149.C900_02763 2.753e-58 211.0 COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,47Q1F@768503|Cytophagia 976|Bacteroidetes P ZIP Zinc transporter - - - - - - - - - - - - Zip CMS3_k127_2112103_1 1123278.KB893590_gene5398 1.741e-294 914.0 COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47JMW@768503|Cytophagia 976|Bacteroidetes I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C CMS3_k127_2112103_26 153721.MYP_55 3.926e-76 264.0 COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,47MHM@768503|Cytophagia 976|Bacteroidetes M Lipid A biosynthesis acyltransferase waaM - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans CMS3_k127_2112103_4 1237149.C900_03224 8.822e-185 589.0 COG4623@1|root,COG4623@2|Bacteria,4NHFW@976|Bacteroidetes,47NX6@768503|Cytophagia 976|Bacteroidetes M soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein mltF - - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT CMS3_k127_2112103_36 643867.Ftrac_1790 3.039e-23 105.0 2CHP7@1|root,34AJV@2|Bacteria,4P6FP@976|Bacteroidetes,47WXM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2112103_8 1237149.C900_03222 3.3e-175 559.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47KM9@768503|Cytophagia 976|Bacteroidetes H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid kmo - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS3_k127_2112103_12 880070.Cycma_1685 5.987e-157 506.0 COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,47KPP@768503|Cytophagia 976|Bacteroidetes E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively kynU - 3.7.1.3 ko:K01556 ko00380,ko01100,map00380,map01100 M00038 R00987,R02668,R03936 RC00284,RC00415 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 CMS3_k127_2112103_10 643867.Ftrac_2833 2.974e-170 539.0 COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 CMS3_k127_2112103_25 153721.MYP_1685 7.744e-93 307.0 COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia 976|Bacteroidetes G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO CMS3_k127_2112103_23 1237149.C900_03218 1.1e-99 331.0 COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,47JB0@768503|Cytophagia 976|Bacteroidetes IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_2112103_3 1237149.C900_03217 4.084e-244 761.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family - - 1.2.1.3,1.2.1.32,1.2.1.85 ko:K00128,ko:K10217 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220 M00038,M00135,M00569 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_2112103_22 1237149.C900_01781 4.674e-103 340.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - CMS3_k127_2112103_0 926549.KI421517_gene314 0.0 1038.0 COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia 976|Bacteroidetes H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C CMS3_k127_2112103_20 1237149.C900_03460 2.019e-111 364.0 COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,47MUR@768503|Cytophagia 976|Bacteroidetes D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA CMS3_k127_2112103_29 313606.M23134_03833 5.462e-68 233.0 COG0105@1|root,COG0105@2|Bacteria,4NM5B@976|Bacteroidetes,47PQ3@768503|Cytophagia 976|Bacteroidetes F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK CMS3_k127_2112103_15 1237149.C900_03206 2.028e-133 432.0 COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,47JVC@768503|Cytophagia 976|Bacteroidetes S phosphoesterase RecJ domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS3_k127_2112103_30 1237149.C900_03205 1.613e-61 223.0 COG0545@1|root,COG0545@2|Bacteria,4NPBZ@976|Bacteroidetes,47XJV@768503|Cytophagia 976|Bacteroidetes M FKBP-type peptidyl-prolyl cis-trans isomerase - - - - - - - - - - - - FKBP_C CMS3_k127_2112103_28 929703.KE386491_gene3454 4.921e-69 239.0 COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,47PE9@768503|Cytophagia 976|Bacteroidetes F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like CMS3_k127_2112103_31 1124780.ANNU01000010_gene3631 4.965e-60 213.0 COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,47P8Z@768503|Cytophagia 976|Bacteroidetes F Belongs to the uridine kinase family udk - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK CMS3_k127_2112103_19 1237149.C900_03200 2.623e-115 381.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG CMS3_k127_2177268_3 153721.MYP_93 1.663e-17 83.0 COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,47MJ5@768503|Cytophagia 976|Bacteroidetes T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS3_k127_2177268_1 1237149.C900_01142 5.227e-83 284.0 COG3170@1|root,COG3170@2|Bacteria,4NF47@976|Bacteroidetes,47M60@768503|Cytophagia 976|Bacteroidetes NU Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 CMS3_k127_2177268_0 1237149.C900_01141 1.959e-91 311.0 COG4324@1|root,COG4324@2|Bacteria,4NF0V@976|Bacteroidetes,47NVX@768503|Cytophagia 976|Bacteroidetes I Putative aminopeptidase - - - - - - - - - - - - Aminopep CMS3_k127_2177268_2 1237149.C900_01140 4.246e-70 248.0 28NIY@1|root,2ZBK8@2|Bacteria,4NM7G@976|Bacteroidetes,47PEJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2210787_18 1237149.C900_01588 2.365e-09 59.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - 3.4.11.2,3.4.24.3 ko:K01256,ko:K01387 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002,ko02042 - - - HEAT_2,HEAT_PBS,Peptidase_M1,Peptidase_M9,Peptidase_M9_N CMS3_k127_2210787_10 1237149.C900_01589 2.502e-91 312.0 COG2972@1|root,COG2972@2|Bacteria,4NFDP@976|Bacteroidetes,47N4N@768503|Cytophagia 976|Bacteroidetes T PFAM histidine kinase internal region - - - - - - - - - - - - His_kinase CMS3_k127_2210787_13 1237149.C900_01590 1.001e-76 269.0 COG2972@1|root,COG2972@2|Bacteria,4NPKE@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase CMS3_k127_2210787_12 1121904.ARBP01000001_gene5369 1.461e-89 302.0 COG3279@1|root,COG3279@2|Bacteria,4NJW4@976|Bacteroidetes 976|Bacteroidetes T LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_2210787_17 742725.HMPREF9450_00762 1.501e-36 141.0 COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,2FTIA@200643|Bacteroidia,22VQ1@171550|Rikenellaceae 976|Bacteroidetes J Translation initiation factor SUI1 - - - ko:K03113 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - SUI1 CMS3_k127_2210787_15 1237149.C900_00284 1.885e-69 245.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp CMS3_k127_2210787_5 1237149.C900_00280 3.079e-112 369.0 COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,47JDA@768503|Cytophagia 976|Bacteroidetes H Belongs to the MenA family. Type 1 subfamily menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA CMS3_k127_2210787_14 866536.Belba_2231 1.135e-71 246.0 COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,47P7U@768503|Cytophagia 976|Bacteroidetes O Belongs to the glutathione peroxidase family gpx1 - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx CMS3_k127_2210787_0 1237149.C900_00279 4.117e-259 811.0 COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,47K91@768503|Cytophagia 976|Bacteroidetes J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d CMS3_k127_2210787_2 1107311.Q767_02560 1.198e-181 571.0 COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1HXQG@117743|Flavobacteriia,2NSM3@237|Flavobacterium 976|Bacteroidetes O Deoxyhypusine synthase dys1 - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS CMS3_k127_2210787_7 1121011.AUCB01000005_gene2387 1.663e-110 366.0 COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,1HX0R@117743|Flavobacteriia,23GHH@178469|Arenibacter 976|Bacteroidetes S Amidinotransferase - - - - - - - - - - - - Amidinotransf CMS3_k127_2210787_8 873517.HMPREF1977_0029 2.61e-102 341.0 COG1834@1|root,COG1834@2|Bacteria,4NEUJ@976|Bacteroidetes,1HWNG@117743|Flavobacteriia,1EQ90@1016|Capnocytophaga 976|Bacteroidetes E amidinotransferase - - - - - - - - - - - - Amidinotransf CMS3_k127_2210787_1 1237149.C900_00272 2.534e-241 751.0 COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,47JRV@768503|Cytophagia 976|Bacteroidetes E PFAM Pyridoxal-dependent decarboxylase, C-terminal sheet domain speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CMS3_k127_2210787_9 1313301.AUGC01000001_gene1534 4.816e-102 338.0 COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes 976|Bacteroidetes S Pfam Glycosyl transferase family 2 dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 CMS3_k127_2210787_3 1279009.ADICEAN_00098 1.004e-135 443.0 COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,47KVD@768503|Cytophagia 976|Bacteroidetes M ABC-type transport system involved in lipoprotein release permease component lolE_1 - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD CMS3_k127_2210787_4 1121904.ARBP01000004_gene874 2.524e-128 421.0 COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,47KTI@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised conserved protein UCP016719 - - - - - - - - - - - - DUF1343 CMS3_k127_2210787_6 1121859.KB890739_gene2599 1.166e-110 365.0 COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,47JDP@768503|Cytophagia 976|Bacteroidetes J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N CMS3_k127_2210787_16 1237149.C900_02640 7.555e-57 203.0 COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,47Q9G@768503|Cytophagia 976|Bacteroidetes H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - 2TM,DHFR_1 CMS3_k127_2210787_11 604354.TSIB_0893 5.892e-91 308.0 COG1171@1|root,arCOG01431@2157|Archaea,2XT4W@28890|Euryarchaeota 28890|Euryarchaeota E Threonine dehydratase ilvA2 - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_4,PALP CMS3_k127_2210787_19 871968.DESME_07775 3.317e-05 47.0 COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,2641B@186807|Peptococcaceae 186801|Clostridia S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE CMS3_k127_223844_15 760192.Halhy_2134 5.493e-167 535.0 COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1IWRU@117747|Sphingobacteriia 976|Bacteroidetes Q COGs COG1228 Imidazolonepropionase and related amidohydrolase - - - - - - - - - - - - Amidohydro_1 CMS3_k127_223844_50 1127692.HMPREF9075_00811 4.85e-33 139.0 COG3884@1|root,COG3884@2|Bacteria,4NMMY@976|Bacteroidetes,1I2IB@117743|Flavobacteriia,1EQDN@1016|Capnocytophaga 976|Bacteroidetes I Acyl-ACP thioesterase - - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE CMS3_k127_223844_58 1121904.ARBP01000027_gene714 2.236e-26 112.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_223844_19 1047013.AQSP01000134_gene1348 6.087e-156 523.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_223844_53 1237149.C900_00635 5.125e-32 129.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - CMS3_k127_223844_31 1123234.AUKI01000019_gene365 2.743e-100 342.0 COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1HY7E@117743|Flavobacteriia 976|Bacteroidetes M D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 CMS3_k127_223844_17 1237149.C900_00747 6.944e-163 527.0 COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family alkH - 1.2.1.3,1.2.1.68 ko:K00128,ko:K00154 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_223844_40 1121904.ARBP01000003_gene6253 4.067e-67 231.0 COG4696@1|root,COG4696@2|Bacteria,4NNW2@976|Bacteroidetes,47PPX@768503|Cytophagia 976|Bacteroidetes S PFAM Phosphoribosyl-ATP pyrophosphohydrolase - - - - - - - - - - - - PRA-PH CMS3_k127_223844_39 102125.Xen7305DRAFT_00029450 1.227e-67 236.0 COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,3VMJH@52604|Pleurocapsales 1117|Cyanobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 CMS3_k127_223844_6 1237149.C900_00750 3.568e-240 764.0 COG1752@1|root,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,47QDC@768503|Cytophagia 976|Bacteroidetes M Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin CMS3_k127_223844_21 1237149.C900_00751 2.84e-146 475.0 COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,47MV0@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 CMS3_k127_223844_5 643867.Ftrac_2502 3.514e-264 837.0 COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,47JTC@768503|Cytophagia 976|Bacteroidetes CO Cytochrome c biogenesis protein transmembrane region dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 CMS3_k127_223844_54 1121373.KB903621_gene1928 1.804e-28 134.0 COG4232@1|root,COG4232@2|Bacteria,4NVNB@976|Bacteroidetes,47SK7@768503|Cytophagia 976|Bacteroidetes CO Disulphide bond corrector protein DsbC - - - - - - - - - - - - DsbC CMS3_k127_223844_8 1237149.C900_00754 8.365e-220 689.0 COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase family M20 M25 M40 dapE - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS3_k127_223844_37 1237149.C900_04539 2.365e-82 278.0 COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,47MPA@768503|Cytophagia 976|Bacteroidetes I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf CMS3_k127_223844_0 1237149.C900_04538 0.0 1507.0 28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_223844_44 153721.MYP_959 4.417e-53 190.0 COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,47Q8I@768503|Cytophagia 976|Bacteroidetes T PFAM Prokaryotic dksA traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR CMS3_k127_223844_36 643867.Ftrac_2757 6.378e-83 278.0 COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,47NG4@768503|Cytophagia 976|Bacteroidetes D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB CMS3_k127_223844_30 926556.Echvi_0719 1.569e-102 339.0 COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,47JIE@768503|Cytophagia 976|Bacteroidetes J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CMS3_k127_223844_9 1120965.AUBV01000004_gene662 4.574e-191 606.0 COG1150@1|root,COG1150@2|Bacteria,4NF3K@976|Bacteroidetes,47JED@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_8,Fer4_9 CMS3_k127_223844_23 1237149.C900_00900 7.134e-136 436.0 COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,47KRT@768503|Cytophagia 976|Bacteroidetes C PFAM Cysteine-rich domain - - - - - - - - - - - - CCG CMS3_k127_223844_49 313598.MED152_05055 3.789e-34 137.0 28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia,3VWFS@52959|Polaribacter 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_223844_7 1237149.C900_00894 4.715e-229 728.0 COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47JJM@768503|Cytophagia 976|Bacteroidetes MU Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA,PD40,TPR_16,TPR_2,TPR_8 CMS3_k127_223844_26 1122180.Lokhon_00646 3.46e-123 407.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2TR5X@28211|Alphaproteobacteria,2P878@245186|Loktanella 28211|Alphaproteobacteria E Peptidase family M20/M25/M40 amaB GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 CMS3_k127_223844_4 1237149.C900_00745 6.029e-308 974.0 COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,47KBD@768503|Cytophagia 976|Bacteroidetes M AsmA-like C-terminal region - - - - - - - - - - - - AsmA,AsmA_2 CMS3_k127_223844_61 1170562.Cal6303_0515 3.117e-22 101.0 COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1HJH3@1161|Nostocales 1117|Cyanobacteria O Peptidyl-prolyl cis-trans isomerase fkpA - 5.2.1.8 ko:K01802,ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C CMS3_k127_223844_20 1121957.ATVL01000006_gene2932 1.942e-154 509.0 COG1305@1|root,COG1305@2|Bacteria,4PMBI@976|Bacteroidetes,47YQ0@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857 CMS3_k127_223844_11 880071.Fleli_1325 5.758e-178 578.0 COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,47KR7@768503|Cytophagia 976|Bacteroidetes E Transglutaminase-like superfamily - - - - - - - - - - - - DUF3857,Transglut_core CMS3_k127_223844_47 313606.M23134_05014 5.588e-41 155.0 COG1959@1|root,COG1959@2|Bacteria,4NR6M@976|Bacteroidetes,47RSD@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - Rrf2 CMS3_k127_223844_69 382464.ABSI01000013_gene1866 1.428e-06 55.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2911,DUF4440,SnoaL_2,SnoaL_3 CMS3_k127_223844_33 1121930.AQXG01000002_gene2373 1.214e-90 302.0 COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,1IQSX@117747|Sphingobacteriia 976|Bacteroidetes L DNA-3-methyladenine glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco CMS3_k127_223844_2 1237149.C900_02054 3.2e-321 1004.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47YDB@768503|Cytophagia 976|Bacteroidetes O Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 CMS3_k127_223844_56 1296416.JACB01000026_gene3919 2.716e-27 113.0 COG1280@1|root,COG1280@2|Bacteria,4NMHH@976|Bacteroidetes,1I1HP@117743|Flavobacteriia,2YIK9@290174|Aquimarina 976|Bacteroidetes E LysE type translocator - - - - - - - - - - - - LysE CMS3_k127_223844_12 471854.Dfer_2714 6.642e-176 561.0 COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase family M20 M25 M40 - - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_223844_55 926549.KI421517_gene1919 1.969e-27 115.0 COG2146@1|root,COG2146@2|Bacteria,4NVFP@976|Bacteroidetes,47S4K@768503|Cytophagia 976|Bacteroidetes P Rieske [2Fe-2S] domain - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske CMS3_k127_223844_3 1237149.C900_03155 2.45e-308 966.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia 976|Bacteroidetes E PFAM Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 CMS3_k127_223844_51 1463885.KL578430_gene6947 2.434e-32 130.0 COG1670@1|root,COG1670@2|Bacteria,2HE22@201174|Actinobacteria 201174|Actinobacteria J SnoaL-like domain - - - - - - - - - - - - SnoaL_2 CMS3_k127_223844_63 1185876.BN8_01920 1.377e-17 83.0 COG1670@1|root,COG1670@2|Bacteria,4NTU9@976|Bacteroidetes,47UWA@768503|Cytophagia 976|Bacteroidetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 CMS3_k127_223844_57 504472.Slin_2140 3.894e-27 111.0 COG1670@1|root,COG1670@2|Bacteria,4NTU9@976|Bacteroidetes,47UWA@768503|Cytophagia 976|Bacteroidetes J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 CMS3_k127_223844_43 1120965.AUBV01000007_gene2714 8.125e-56 203.0 COG3548@1|root,COG3548@2|Bacteria,4NW8Z@976|Bacteroidetes,47V92@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 CMS3_k127_223844_59 313606.M23134_06953 1.267e-24 122.0 COG4249@1|root,COG4249@2|Bacteria 2|Bacteria S B-1 B cell differentiation - - - - - - - - - - - - Amidase_2,PG_binding_1,Peptidase_C14,WD40 CMS3_k127_223844_65 28072.Nos7524_2352 1.598e-12 82.0 COG0464@1|root,COG0464@2|Bacteria,1G062@1117|Cyanobacteria,1HM1J@1161|Nostocales 1117|Cyanobacteria O PFAM ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA,AAA_2 CMS3_k127_223844_35 643867.Ftrac_1104 7.883e-86 319.0 COG4249@1|root,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes,47UFX@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 CMS3_k127_223844_22 1237149.C900_03194 3.616e-139 451.0 COG0520@1|root,COG0520@2|Bacteria,4NJEQ@976|Bacteroidetes,47NQ3@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_223844_24 402612.FP0075 5.146e-132 434.0 COG3488@1|root,COG3488@2|Bacteria,4NGBS@976|Bacteroidetes,1HY8W@117743|Flavobacteriia,2NVR8@237|Flavobacterium 976|Bacteroidetes C Di-haem oxidoreductase, putative peroxidase - - - - - - - - - - - - DHOR CMS3_k127_223844_60 1121904.ARBP01000035_gene1753 5.742e-23 103.0 COG0723@1|root,COG0723@2|Bacteria,4NJPJ@976|Bacteroidetes 976|Bacteroidetes C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636 ko00195,ko01100,map00195,map01100 M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske CMS3_k127_223844_27 1121904.ARBP01000035_gene1752 4.941e-113 377.0 COG1730@1|root,COG1730@2|Bacteria 2|Bacteria O sister chromatid segregation - - - - - - - - - - - - - CMS3_k127_223844_46 153721.MYP_1866 6.757e-44 163.0 COG0346@1|root,COG0346@2|Bacteria,4NRSZ@976|Bacteroidetes,47QSC@768503|Cytophagia 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase CMS3_k127_223844_18 1237149.C900_00764 2.281e-158 509.0 COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M0Y@768503|Cytophagia 976|Bacteroidetes C Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB CMS3_k127_223844_38 1121904.ARBP01000001_gene5620 2.644e-80 284.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,PAS_8 CMS3_k127_223844_16 1237149.C900_01528 1.635e-165 532.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_223844_66 1237149.C900_02035 6.28e-11 68.0 2E3RG@1|root,32YP4@2|Bacteria,4NUUF@976|Bacteroidetes,47SX9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_223844_14 1124780.ANNU01000015_gene2000 4.624e-174 551.0 COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes,47M9W@768503|Cytophagia 976|Bacteroidetes J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 CMS3_k127_223844_25 1237149.C900_00793 5.97e-132 435.0 2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,47PAS@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Beta_helix CMS3_k127_223844_42 1191523.MROS_1498 1.8e-56 199.0 COG0432@1|root,COG0432@2|Bacteria 2|Bacteria S Uncharacterised protein family UPF0047 yjbQ - - - - - - - - - - - UPF0047 CMS3_k127_223844_48 1237149.C900_03160 2.464e-37 147.0 COG1714@1|root,COG1714@2|Bacteria,4NW7J@976|Bacteroidetes,47X24@768503|Cytophagia 976|Bacteroidetes S RDD family - - - - - - - - - - - - RDD CMS3_k127_223844_64 1408473.JHXO01000008_gene2641 1.57e-17 85.0 2EFW8@1|root,339NG@2|Bacteria,4NXQM@976|Bacteroidetes,2FVI3@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_223844_34 1124780.ANNU01000006_gene2868 1.982e-87 304.0 COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia 976|Bacteroidetes M PDZ DHR GLGF domain protein - - - - - - - - - - - - Asp_protease_2,PDZ,PDZ_2 CMS3_k127_223844_41 929562.Emtol_2098 9.571e-61 215.0 COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,47Q15@768503|Cytophagia 976|Bacteroidetes S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox CMS3_k127_223844_45 1237149.C900_03495 5.427e-47 172.0 COG0251@1|root,COG0251@2|Bacteria,4NPT2@976|Bacteroidetes,47QK8@768503|Cytophagia 976|Bacteroidetes J Endoribonuclease L-PSP - - - - - - - - - - - - Aldo_ket_red,Ribonuc_L-PSP CMS3_k127_223844_13 1237149.C900_02057 6.1e-175 554.0 COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,47MPT@768503|Cytophagia 976|Bacteroidetes J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CMS3_k127_223844_32 1279009.ADICEAN_04006 3.166e-91 308.0 COG2515@1|root,COG2515@2|Bacteria,4NEP9@976|Bacteroidetes,47JNZ@768503|Cytophagia 976|Bacteroidetes E 1-aminocyclopropane-1-carboxylate deaminase acdS - 3.5.99.7 ko:K01505 ko00270,map00270 - R00997 RC00419 ko00000,ko00001,ko01000 - - - PALP CMS3_k127_223844_10 153721.MYP_4409 3.581e-190 602.0 COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,47K0I@768503|Cytophagia 976|Bacteroidetes O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI CMS3_k127_223844_28 1237149.C900_02854 4.936e-112 368.0 COG0300@1|root,COG0300@2|Bacteria,4NEMK@976|Bacteroidetes,47JGN@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS3_k127_223844_1 1237149.C900_02745 0.0 1321.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia 976|Bacteroidetes L PFAM Helicase conserved C-terminal domain - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N CMS3_k127_223844_29 1237149.C900_02744 3.556e-108 359.0 COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,47M0Q@768503|Cytophagia 976|Bacteroidetes M ABC-type transport system involved in lipoprotein release permease component lolE_2 - - ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125,3.A.1.15.3,3.A.1.15.5 - - FtsX,MacB_PCD CMS3_k127_2244161_5 1121374.KB891575_gene1103 2.234e-84 289.0 COG2040@1|root,COG2040@2|Bacteria,1QU2A@1224|Proteobacteria,1RS8M@1236|Gammaproteobacteria 1236|Gammaproteobacteria H homocysteine mmuM GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans CMS3_k127_2244161_7 472175.EL18_01162 2.018e-76 268.0 COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,43JDU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Eukaryotic DNA topoisomerase I, catalytic core MA20_25110 - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_I CMS3_k127_2244161_0 865937.Gilli_0352 7.639e-251 790.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,1HXGN@117743|Flavobacteriia,2P69G@244698|Gillisia 976|Bacteroidetes P TrkA-C domain - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N CMS3_k127_2244161_1 1121904.ARBP01000008_gene3401 3.056e-218 706.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_2244161_10 1121904.ARBP01000017_gene5134 6.321e-43 159.0 COG1695@1|root,COG1695@2|Bacteria,4P6G7@976|Bacteroidetes,47VZ7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_2244161_8 471854.Dfer_1018 7.024e-57 201.0 COG0454@1|root,COG0456@2|Bacteria,4NQ7Z@976|Bacteroidetes,47QG5@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 CMS3_k127_2244161_12 655815.ZPR_2286 2.421e-35 140.0 COG1846@1|root,COG1846@2|Bacteria,4NQNI@976|Bacteroidetes,1I3F3@117743|Flavobacteriia 976|Bacteroidetes K MarR family - - - - - - - - - - - - MarR,MarR_2 CMS3_k127_2244161_2 1237149.C900_04258 1.438e-154 492.0 COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,47JVM@768503|Cytophagia 976|Bacteroidetes E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738,ko:K12339 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03132,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS3_k127_2244161_4 755732.Fluta_2259 4.249e-114 378.0 COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZK0@117743|Flavobacteriia,2PC39@246874|Cryomorphaceae 976|Bacteroidetes K PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_2244161_3 1121859.KB890759_gene1973 7.442e-149 479.0 COG2267@1|root,COG2267@2|Bacteria,4NIGT@976|Bacteroidetes 976|Bacteroidetes I Alpha/beta hydrolase family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Hydrolase_4 CMS3_k127_2244161_6 1506583.JQJY01000007_gene4107 7.265e-78 266.0 COG4775@1|root,COG4775@2|Bacteria,4NRT9@976|Bacteroidetes,1I4PV@117743|Flavobacteriia,2NYF2@237|Flavobacterium 976|Bacteroidetes M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - CMS3_k127_2244161_9 485918.Cpin_2473 7.319e-53 192.0 COG2318@1|root,COG2318@2|Bacteria,4NQNZ@976|Bacteroidetes 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_2244161_11 1286632.P278_03710 3.752e-38 144.0 COG2044@1|root,COG2044@2|Bacteria,4P2I4@976|Bacteroidetes,1I8SH@117743|Flavobacteriia 976|Bacteroidetes S DsrE/DsrF-like family - - - - - - - - - - - - DrsE CMS3_k127_2250364_4 1121104.AQXH01000003_gene329 1.053e-30 122.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase CMS3_k127_2250364_1 388413.ALPR1_00680 1.152e-146 473.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cu_amine_oxidN1,Phytase-like CMS3_k127_2250364_0 1267211.KI669560_gene418 0.0 1013.0 COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IVF5@117747|Sphingobacteriia 976|Bacteroidetes S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS3_k127_2250364_2 1237149.C900_01756 6.145e-67 231.0 COG3832@1|root,COG3832@2|Bacteria,4NPKI@976|Bacteroidetes,47UX1@768503|Cytophagia 976|Bacteroidetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 CMS3_k127_2250364_3 1237149.C900_01755 3.859e-47 176.0 COG2169@1|root,COG2169@2|Bacteria 2|Bacteria K sequence-specific DNA binding melR GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.1.31.1,3.2.2.21 ko:K01174,ko:K03490,ko:K13529,ko:K15051 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,Cupin_2,HTH_18,HTH_AraC CMS3_k127_2268911_2 1313301.AUGC01000004_gene2230 4.753e-88 301.0 COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 CMS3_k127_2268911_3 1237149.C900_01010 2.784e-86 289.0 COG1595@1|root,COG1595@2|Bacteria,4NEFR@976|Bacteroidetes,47JFG@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_2268911_9 1123057.P872_06665 1.543e-09 62.0 2EK82@1|root,33DYE@2|Bacteria,4NYF0@976|Bacteroidetes,47SMK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - zf-HC2 CMS3_k127_2268911_6 1237149.C900_01012 1.61e-67 235.0 COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,47M4J@768503|Cytophagia 976|Bacteroidetes F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin CMS3_k127_2268911_4 471854.Dfer_3826 3.422e-75 256.0 COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes,47JKF@768503|Cytophagia 976|Bacteroidetes H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CMS3_k127_2268911_5 1237149.C900_01018 9.484e-72 246.0 COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,47P9Z@768503|Cytophagia 976|Bacteroidetes J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF CMS3_k127_2268911_1 1279009.ADICEAN_00814 1.031e-118 385.0 COG0528@1|root,COG0528@2|Bacteria,4NE8Z@976|Bacteroidetes,47JC6@768503|Cytophagia 976|Bacteroidetes F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase CMS3_k127_2268911_7 866536.Belba_1689 7.705e-34 136.0 COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia 976|Bacteroidetes I Acetyl propionyl-CoA carboxylase alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl CMS3_k127_2268911_10 1341151.ASZU01000033_gene1638 1.445e-06 51.0 2EG8N@1|root,33A0G@2|Bacteria,1UPXM@1239|Firmicutes,4IVCT@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - CMS3_k127_2268911_8 1236518.BAKP01000026_gene1675 7.023e-12 66.0 2DD50@1|root,2ZGIJ@2|Bacteria,4P8A2@976|Bacteroidetes,2FZIU@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2268911_0 1048983.EL17_05105 6.512e-119 383.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia 976|Bacteroidetes J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 CMS3_k127_22841_8 545695.TREAZ_1756 2.295e-11 75.0 COG0457@1|root,COG3210@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,2J58Z@203691|Spirochaetes 203691|Spirochaetes M Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_12,TPR_16,TPR_2,TPR_7,TPR_8 CMS3_k127_22841_2 643867.Ftrac_0465 5.856e-97 332.0 COG0642@1|root,COG2205@2|Bacteria,4P2BP@976|Bacteroidetes 976|Bacteroidetes T signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA CMS3_k127_22841_0 1237149.C900_00537 5.167e-212 680.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 CMS3_k127_22841_4 616991.JPOO01000003_gene2285 1.634e-64 224.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1I17D@117743|Flavobacteriia,23HUE@178469|Arenibacter 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_22841_5 1237149.C900_03285 2.883e-44 166.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_22841_9 1144275.COCOR_00143 4.383e-05 52.0 COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria 1224|Proteobacteria S YCII-related domain - - - - - - - - - - - - YCII CMS3_k127_22841_7 387093.SUN_0762 2.844e-35 149.0 COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2YTDF@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - CMS3_k127_22841_3 1379698.RBG1_1C00001G0108 1.436e-80 278.0 COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria 2|Bacteria P Belongs to the bacterial solute-binding protein 9 family znuA - - ko:K02077,ko:K09815,ko:K09818 ko02010,map02010 M00242,M00243,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA CMS3_k127_22841_6 1379698.RBG1_1C00001G0109 8.108e-42 164.0 COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria 2|Bacteria U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 CMS3_k127_22841_1 700598.Niako_5205 6.357e-185 606.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IV3C@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_2358638_2 1237149.C900_05604 6.606e-161 517.0 COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia 976|Bacteroidetes M HlyD membrane-fusion protein of T1SS - - - - - - - - - - - - HlyD,HlyD_3,HlyD_D23 CMS3_k127_2358638_1 1237149.C900_05605 8.625e-182 579.0 COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47JWH@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_2358638_0 1237149.C900_02626 2.095e-282 875.0 COG1012@1|root,COG1012@2|Bacteria 2|Bacteria C belongs to the aldehyde dehydrogenase family paaN - - - - - - - - - - - Aldedh CMS3_k127_2358638_3 1237149.C900_02634 1.222e-93 313.0 COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,47PQP@768503|Cytophagia 976|Bacteroidetes S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS3_k127_2430041_7 1237149.C900_00261 8.207e-31 126.0 COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia 976|Bacteroidetes S PFAM PASTA domain spk1 - 2.7.11.1,6.3.2.4 ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01001,ko01011 - - - PASTA CMS3_k127_2430041_2 1237149.C900_00260 1.644e-111 383.0 28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,47JC7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2430041_0 1296416.JACB01000003_gene706 3.697e-126 409.0 COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,1HWS5@117743|Flavobacteriia,2YJAC@290174|Aquimarina 976|Bacteroidetes S Polyphosphate kinase 2 (PPK2) - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 CMS3_k127_2430041_3 1317122.ATO12_01035 4.822e-100 333.0 COG2326@1|root,COG2326@2|Bacteria,4NEXB@976|Bacteroidetes,1HXCV@117743|Flavobacteriia,2YINC@290174|Aquimarina 976|Bacteroidetes S Polyphosphate kinase 2 (PPK2) - - 2.7.4.1 ko:K22468 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PPK2 CMS3_k127_2430041_1 1237149.C900_00515 3.421e-123 407.0 COG0750@1|root,COG0750@2|Bacteria,4NI5C@976|Bacteroidetes,47K57@768503|Cytophagia 976|Bacteroidetes M Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 CMS3_k127_2430041_6 925409.KI911562_gene650 1.197e-33 139.0 COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,1IS3Y@117747|Sphingobacteriia 976|Bacteroidetes S HAD-superfamily hydrolase subfamily IA, variant 3 yihX - 3.1.3.10 ko:K20866 ko00010,ko01120,map00010,map01120 - R00947 RC00078 ko00000,ko00001,ko01000 - - - HAD_2 CMS3_k127_2430041_9 1313301.AUGC01000003_gene2119 1.68e-10 70.0 COG1266@1|root,COG1266@2|Bacteria,4P5RH@976|Bacteroidetes 976|Bacteroidetes S CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_2430041_5 665571.STHERM_c18100 5.912e-45 183.0 COG0300@1|root,COG0300@2|Bacteria,2J5I8@203691|Spirochaetes 203691|Spirochaetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short CMS3_k127_2430041_4 1237149.C900_04174 3.623e-69 256.0 COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,47KEU@768503|Cytophagia 976|Bacteroidetes GM NmrA-like family dfrA - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase CMS3_k127_2510675_0 1237149.C900_02790 3.202e-299 930.0 COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia 976|Bacteroidetes O PFAM Cytochrome c assembly protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm CMS3_k127_2510675_5 643867.Ftrac_2484 3.057e-51 184.0 COG2332@1|root,COG2332@2|Bacteria,4NN85@976|Bacteroidetes,47PIE@768503|Cytophagia 976|Bacteroidetes O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH - - - ko:K02197 - - - - ko00000 - - - CcmE CMS3_k127_2510675_3 1124780.ANNU01000005_gene2415 2.502e-91 305.0 COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,47MYQ@768503|Cytophagia 976|Bacteroidetes O PFAM Cytochrome c assembly protein ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm CMS3_k127_2510675_1 153721.MYP_999 2.108e-187 590.0 COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,47K8D@768503|Cytophagia 976|Bacteroidetes M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd CMS3_k127_2510675_2 926549.KI421517_gene2194 2.225e-143 462.0 COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia 976|Bacteroidetes GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase CMS3_k127_2510675_4 1239962.C943_00614 5.669e-80 272.0 COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,47K0P@768503|Cytophagia 976|Bacteroidetes O ABC-type transport system involved in cytochrome c biogenesis permease component ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB CMS3_k127_2510675_6 643867.Ftrac_2489 7.643e-44 167.0 2A7E3@1|root,30WBH@2|Bacteria,4P9R0@976|Bacteroidetes,47RWQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2514771_6 1267211.KI669560_gene1865 2.197e-06 54.0 COG1961@1|root,COG1961@2|Bacteria,4NHXM@976|Bacteroidetes 976|Bacteroidetes L Recombinase - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CMS3_k127_2514771_1 1237149.C900_01576 2.219e-96 325.0 COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,47JSE@768503|Cytophagia 976|Bacteroidetes S PFAM Nucleoside recognition spmA - - ko:K06373 - - - - ko00000 - - - Gate CMS3_k127_2514771_4 1237149.C900_01572 1.87e-54 197.0 COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes,47QR6@768503|Cytophagia 976|Bacteroidetes CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin CMS3_k127_2514771_0 1237149.C900_01566 8.476e-188 596.0 COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia 976|Bacteroidetes E PFAM Sodium alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp CMS3_k127_2514771_2 1313301.AUGC01000007_gene628 9.961e-90 302.0 COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes 976|Bacteroidetes E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase CMS3_k127_2528963_2 566466.NOR53_491 2.736e-09 63.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C CMS3_k127_2528963_0 926556.Echvi_3095 2.302e-181 583.0 COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_2528963_1 1185876.BN8_03058 7.28e-110 368.0 COG0577@1|root,COG0577@2|Bacteria,4NI0C@976|Bacteroidetes,47M9R@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_2555114_27 886293.Sinac_4765 4.514e-46 184.0 COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes 203682|Planctomycetes U Pkd domain containing protein - - 2.7.11.1 ko:K12567 ko05410,ko05414,map05410,map05414 - - - ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812 - - - - CMS3_k127_2555114_21 1124780.ANNU01000073_gene717 1.608e-57 218.0 COG2067@1|root,COG2067@2|Bacteria,4NG4A@976|Bacteroidetes,47V9Y@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - - CMS3_k127_2555114_18 643867.Ftrac_0814 1.489e-82 299.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2 CMS3_k127_2555114_23 1237149.C900_03842 6.589e-52 193.0 2EHJH@1|root,32W49@2|Bacteria,4NTI9@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2555114_24 1237149.C900_05577 8.963e-51 186.0 298PT@1|root,2ZVU7@2|Bacteria,4NPTP@976|Bacteroidetes,47RY6@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2555114_8 485918.Cpin_1877 2.052e-163 525.0 COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,1IP0X@117747|Sphingobacteriia 976|Bacteroidetes H AMP-binding enzyme paaK - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 CMS3_k127_2555114_33 485918.Cpin_1876 2.044e-27 116.0 COG0736@1|root,COG0736@2|Bacteria,4P5DA@976|Bacteroidetes 976|Bacteroidetes I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS CMS3_k127_2555114_6 1122605.KB893626_gene2729 9.087e-187 598.0 COG0457@1|root,COG0457@2|Bacteria,4PKJM@976|Bacteroidetes,1J0ZM@117747|Sphingobacteriia 976|Bacteroidetes S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT CMS3_k127_2555114_7 1237149.C900_02902 1.571e-175 563.0 COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,47K5X@768503|Cytophagia 976|Bacteroidetes Q Flavin containing amine oxidoreductase - - 1.3.99.23 ko:K09516 ko00830,map00830 - R07163 RC01835 ko00000,ko00001,ko01000 - - - Amino_oxidase,NAD_binding_8 CMS3_k127_2555114_0 1122605.KB893626_gene2733 0.0 1158.0 COG0204@1|root,COG2227@1|root,COG4258@1|root,COG0204@2|Bacteria,COG2227@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1IQPB@117747|Sphingobacteriia 976|Bacteroidetes I Phosphate acyltransferases - - - ko:K07003 - - - - ko00000 - - - Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31 CMS3_k127_2555114_11 929713.NIASO_17970 1.049e-132 434.0 COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1IS4P@117747|Sphingobacteriia 976|Bacteroidetes M Uncharacterized protein conserved in bacteria (DUF2062) - - - - - - - - - - - - Acyltransferase,DUF2062,Glycos_transf_2 CMS3_k127_2555114_36 714943.Mucpa_6799 1.041e-20 95.0 COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,1IUPZ@117747|Sphingobacteriia 976|Bacteroidetes I FabA-like domain fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CMS3_k127_2555114_25 485918.Cpin_1869 4.426e-47 177.0 COG2834@1|root,COG2834@2|Bacteria,4NT30@976|Bacteroidetes,1IU2D@117747|Sphingobacteriia 976|Bacteroidetes M Outer membrane lipoprotein carrier protein LolA lolA - - ko:K03634 - - - - ko00000 - - - LolA CMS3_k127_2555114_20 485918.Cpin_1868 5.911e-64 228.0 COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1ISZA@117747|Sphingobacteriia 976|Bacteroidetes G Polysaccharide deacetylase pgdA - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - DUF3298,Polysacc_deac_1 CMS3_k127_2555114_17 485918.Cpin_1867 4.002e-91 312.0 COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1ISE9@117747|Sphingobacteriia 976|Bacteroidetes IQ Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2,ketoacyl-synt CMS3_k127_2555114_10 929713.NIASO_13495 2.081e-138 450.0 COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,1IRGP@117747|Sphingobacteriia 976|Bacteroidetes IQ Belongs to the beta-ketoacyl-ACP synthases family - - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_2555114_32 485918.Cpin_1865 1.536e-27 113.0 COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,1ITV3@117747|Sphingobacteriia 976|Bacteroidetes IQ Phosphopantetheine attachment site acpP2 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_2555114_28 929713.NIASO_13505 1.33e-45 171.0 COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,1ITHW@117747|Sphingobacteriia 976|Bacteroidetes IQ 3-oxoacyl-ACP synthase - - - - - - - - - - - - - CMS3_k127_2555114_9 153721.MYP_192 4.441e-162 520.0 COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia 976|Bacteroidetes C Tryptophan halogenase fixC - - - - - - - - - - - Trp_halogenase CMS3_k127_2555114_12 485918.Cpin_1862 6.576e-118 389.0 COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IUWM@117747|Sphingobacteriia 976|Bacteroidetes Q O-methyltransferase crtF - - - - - - - - - - - Methyltransf_2 CMS3_k127_2555114_14 929713.NIASO_13525 5.186e-105 352.0 COG0304@1|root,COG0304@2|Bacteria,4NE8K@976|Bacteroidetes,1IPY4@117747|Sphingobacteriia 976|Bacteroidetes IQ Belongs to the beta-ketoacyl-ACP synthases family fabF2 - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_2555114_29 485918.Cpin_1860 2.829e-45 168.0 COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,1ITSJ@117747|Sphingobacteriia 976|Bacteroidetes S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 CMS3_k127_2555114_35 1313421.JHBV01000138_gene1237 1.963e-22 106.0 2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,1IZ7S@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2555114_31 714943.Mucpa_6804 8.832e-30 123.0 COG4706@1|root,COG4706@2|Bacteria,4NSB5@976|Bacteroidetes,1IU4J@117747|Sphingobacteriia 976|Bacteroidetes I dehydratase - - - - - - - - - - - - - CMS3_k127_2555114_15 485918.Cpin_1857 3.731e-100 334.0 COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,1IT2S@117747|Sphingobacteriia 976|Bacteroidetes S Bacterial lipid A biosynthesis acyltransferase - - - - - - - - - - - - Lip_A_acyltrans CMS3_k127_2555114_34 1237149.C900_02916 1.222e-26 110.0 COG0236@1|root,COG0236@2|Bacteria,4NV57@976|Bacteroidetes,47SD1@768503|Cytophagia 976|Bacteroidetes IQ acyl carrier protein acpP_2 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_2555114_5 485918.Cpin_1855 1.247e-194 614.0 COG0304@1|root,COG0304@2|Bacteria,4NFBN@976|Bacteroidetes,1IR9V@117747|Sphingobacteriia 976|Bacteroidetes IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_2555114_13 153721.MYP_4250 2.097e-105 347.0 COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,47N90@768503|Cytophagia 976|Bacteroidetes IQ KR domain fabG3 - 1.1.1.100,1.1.1.36 ko:K00023,ko:K00059 ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212 M00083,M00373,M00572 R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00103,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_2555114_3 485918.Cpin_1853 1.841e-202 642.0 COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1IQ55@117747|Sphingobacteriia 976|Bacteroidetes E Aromatic amino acid lyase hutH - 4.3.1.23,4.3.1.3 ko:K01745,ko:K10774 ko00340,ko00350,ko01100,map00340,map00350,map01100 M00045 R00737,R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic CMS3_k127_2555114_4 1124780.ANNU01000019_gene1740 2.463e-197 659.0 COG4447@1|root,COG4447@2|Bacteria,4NI13@976|Bacteroidetes,47NV6@768503|Cytophagia 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_2555114_19 1121920.AUAU01000012_gene2642 2.32e-70 252.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - Beta_helix,Calx-beta,SdrD_B CMS3_k127_2555114_22 592015.HMPREF1705_00103 3.813e-56 207.0 COG2897@1|root,COG2897@2|Bacteria,3TA04@508458|Synergistetes 508458|Synergistetes P PFAM Rhodanese domain protein - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese CMS3_k127_2555114_2 1286632.P278_33300 4.866e-208 657.0 COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia 976|Bacteroidetes P Arylsulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C CMS3_k127_2555114_1 1121904.ARBP01000003_gene6496 1.817e-263 837.0 COG0308@1|root,COG0308@2|Bacteria,4NGTZ@976|Bacteroidetes,47MWS@768503|Cytophagia 976|Bacteroidetes E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 CMS3_k127_2555114_30 866536.Belba_0973 1.999e-44 165.0 COG0662@1|root,COG0662@2|Bacteria,4NS6V@976|Bacteroidetes,47QTI@768503|Cytophagia 976|Bacteroidetes G mannose-6-phosphate isomerase - - - - - - - - - - - - Cupin_2 CMS3_k127_2555114_16 1519464.HY22_13050 8.807e-95 326.0 COG2382@1|root,COG2382@2|Bacteria 2|Bacteria P enterobactin catabolic process yjcH - - ko:K07214 - - - - ko00000 - - - Esterase CMS3_k127_2636916_4 313606.M23134_02050 8.068e-29 124.0 COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_2636916_0 1279009.ADICEAN_00515 3.974e-141 473.0 COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_2636916_6 388413.ALPR1_01500 1.485e-18 91.0 COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes,47QI2@768503|Cytophagia 976|Bacteroidetes S DoxX - - - - - - - - - - - - DoxX CMS3_k127_2636916_3 216432.CA2559_04115 2.144e-52 191.0 28P81@1|root,2ZC26@2|Bacteria,4NMAX@976|Bacteroidetes,1IJFA@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2636916_5 1185876.BN8_01660 2.199e-26 126.0 COG1874@1|root,COG2374@1|root,COG2755@1|root,COG4625@1|root,COG1874@2|Bacteria,COG2374@2|Bacteria,COG2755@2|Bacteria,COG4625@2|Bacteria,4NI5S@976|Bacteroidetes,47NAE@768503|Cytophagia 976|Bacteroidetes G Endonuclease/Exonuclease/phosphatase family - - - ko:K07004 - - - - ko00000 - - - Big_5,Calx-beta,Exo_endo_phos,He_PIG,LTD,VCBS CMS3_k127_2636916_1 1121859.KB890759_gene1906 2.787e-80 273.0 COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,47JY6@768503|Cytophagia 976|Bacteroidetes J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 CMS3_k127_2636916_2 1237149.C900_03417 1.146e-71 250.0 COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,47K0F@768503|Cytophagia 976|Bacteroidetes H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M CMS3_k127_2678193_5 1124780.ANNU01000064_gene448 8.365e-24 106.0 COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,47KF7@768503|Cytophagia 976|Bacteroidetes U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas CMS3_k127_2678193_0 1237149.C900_05936 1.984e-281 872.0 COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,47KXM@768503|Cytophagia 976|Bacteroidetes F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase CMS3_k127_2678193_7 1237149.C900_05933 0.0001496 44.0 COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia 976|Bacteroidetes P TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF CMS3_k127_2678193_1 1237149.C900_05056 1.947e-211 666.0 COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,47KFG@768503|Cytophagia 976|Bacteroidetes J Poly A polymerase head domain cca - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd CMS3_k127_2678193_4 1237149.C900_05057 2.505e-55 201.0 COG0457@1|root,COG0457@2|Bacteria,4NSYY@976|Bacteroidetes,47R4Q@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - ANAPC3,TPR_2,TPR_8 CMS3_k127_2678193_3 1237149.C900_05058 4.023e-57 204.0 COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,47P7T@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_2678193_6 743722.Sph21_1088 4.639e-11 70.0 2A95J@1|root,30YA2@2|Bacteria,4NP9E@976|Bacteroidetes,1ITH5@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2678193_2 1237149.C900_05060 7.908e-75 254.0 COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,47MP4@768503|Cytophagia 976|Bacteroidetes D PFAM ABC transporter ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran CMS3_k127_2693857_3 1048983.EL17_05105 1.423e-237 736.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,47JYT@768503|Cytophagia 976|Bacteroidetes J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 CMS3_k127_2693857_45 1124780.ANNU01000035_gene255 1.156e-21 96.0 COG0690@1|root,COG0690@2|Bacteria,4NX53@976|Bacteroidetes,47RVC@768503|Cytophagia 976|Bacteroidetes U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE CMS3_k127_2693857_13 1237149.C900_04670 5.256e-99 325.0 COG0250@1|root,COG0250@2|Bacteria,4NF2X@976|Bacteroidetes,47KBF@768503|Cytophagia 976|Bacteroidetes K Participates in transcription elongation, termination and antitermination nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG CMS3_k127_2693857_21 1121904.ARBP01000007_gene2900 6.481e-76 256.0 COG0080@1|root,COG0080@2|Bacteria,4NM60@976|Bacteroidetes,47PEZ@768503|Cytophagia 976|Bacteroidetes J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N CMS3_k127_2693857_12 643867.Ftrac_3022 4.993e-113 368.0 COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,47JJZ@768503|Cytophagia 976|Bacteroidetes J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 CMS3_k127_2693857_25 1279009.ADICEAN_00802 3.095e-65 227.0 COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,47JGP@768503|Cytophagia 976|Bacteroidetes J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 CMS3_k127_2693857_32 1121957.ATVL01000006_gene2853 3.356e-56 198.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,47PSQ@768503|Cytophagia 976|Bacteroidetes J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N CMS3_k127_2693857_1 1237149.C900_04675 0.0 2250.0 COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,47JXH@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 CMS3_k127_2693857_0 1237149.C900_04676 0.0 2471.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,47JP0@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 CMS3_k127_2693857_34 1237149.C900_04677 5.863e-52 185.0 COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,47R37@768503|Cytophagia 976|Bacteroidetes T Protein of unknown function (DUF3467) - - - - - - - - - - - - DUF3467 CMS3_k127_2693857_22 643867.Ftrac_3028 5.325e-71 241.0 COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,47PCE@768503|Cytophagia 976|Bacteroidetes J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 CMS3_k127_2693857_20 1239962.C943_00514 1.614e-76 258.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,47P7P@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 CMS3_k127_2693857_2 452471.Aasi_0125 0.0 1162.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia 976|Bacteroidetes J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CMS3_k127_2693857_31 1237149.C900_04681 1.003e-56 198.0 COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,47Q8W@768503|Cytophagia 976|Bacteroidetes J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 CMS3_k127_2693857_14 1239962.C943_00511 1.144e-95 316.0 COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,47KMY@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 CMS3_k127_2693857_17 1237149.C900_01037 1.832e-91 304.0 COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,47J8V@768503|Cytophagia 976|Bacteroidetes J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 CMS3_k127_2693857_41 1279009.ADICEAN_00790 3.001e-36 139.0 COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,47R4F@768503|Cytophagia 976|Bacteroidetes J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 CMS3_k127_2693857_9 926549.KI421517_gene260 2.022e-129 417.0 COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes,47JS0@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C CMS3_k127_2693857_36 643867.Ftrac_3036 5.452e-48 172.0 COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,47QCA@768503|Cytophagia 976|Bacteroidetes J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 CMS3_k127_2693857_35 1124780.ANNU01000035_gene237 9.655e-51 185.0 COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,47QFH@768503|Cytophagia 976|Bacteroidetes J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 CMS3_k127_2693857_10 1237149.C900_01042 4.448e-129 415.0 COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,47MFE@768503|Cytophagia 976|Bacteroidetes J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C CMS3_k127_2693857_23 1124780.ANNU01000035_gene235 1.691e-70 240.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,47P74@768503|Cytophagia 976|Bacteroidetes J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 CMS3_k127_2693857_47 1237149.C900_01044 1.131e-17 83.0 COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,47S5W@768503|Cytophagia 976|Bacteroidetes J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 CMS3_k127_2693857_40 1124780.ANNU01000035_gene234 2.578e-37 141.0 COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,47R6N@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 CMS3_k127_2693857_26 643867.Ftrac_3042 1.174e-64 222.0 COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,47PQH@768503|Cytophagia 976|Bacteroidetes J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 CMS3_k127_2693857_37 761193.Runsl_1690 3.164e-47 173.0 COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,47R7A@768503|Cytophagia 976|Bacteroidetes J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 CMS3_k127_2693857_16 1237149.C900_01048 6.907e-94 312.0 COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,47KSN@768503|Cytophagia 976|Bacteroidetes J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C CMS3_k127_2693857_38 1166018.FAES_5326 5.877e-42 155.0 COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,47QB0@768503|Cytophagia 976|Bacteroidetes J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 CMS3_k127_2693857_27 1124780.ANNU01000035_gene229 1.305e-61 214.0 COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,47PPU@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 CMS3_k127_2693857_19 1279009.ADICEAN_00777 1.141e-81 274.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,47PER@768503|Cytophagia 976|Bacteroidetes J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 CMS3_k127_2693857_42 1237149.C900_01052 4.64e-35 136.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,47RC9@768503|Cytophagia 976|Bacteroidetes J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p CMS3_k127_2693857_18 1237149.C900_01053 1.392e-89 297.0 COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,47M7G@768503|Cytophagia 976|Bacteroidetes J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C CMS3_k127_2693857_44 1237149.C900_01054 4.162e-22 96.0 COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 CMS3_k127_2693857_30 153721.MYP_1347 1.517e-57 203.0 COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes,47PP0@768503|Cytophagia 976|Bacteroidetes J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A CMS3_k127_2693857_4 1124780.ANNU01000035_gene224 1.436e-214 672.0 COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,47JRD@768503|Cytophagia 976|Bacteroidetes U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY CMS3_k127_2693857_11 1237149.C900_01057 5.459e-124 401.0 COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,47KDT@768503|Cytophagia 976|Bacteroidetes E TIGRFAM methionine aminopeptidase, type I map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 CMS3_k127_2693857_39 1124780.ANNU01000035_gene222 2.42e-38 143.0 COG0361@1|root,COG0361@2|Bacteria,4NS6S@976|Bacteroidetes,47RFD@768503|Cytophagia 976|Bacteroidetes J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a CMS3_k127_2693857_48 1279009.ADICEAN_00769 6.638e-15 75.0 COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,47SMT@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 CMS3_k127_2693857_28 1237149.C900_01060 3.821e-61 212.0 COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,47PRH@768503|Cytophagia 976|Bacteroidetes J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 CMS3_k127_2693857_24 1237149.C900_01061 2.15e-68 233.0 COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,47Q07@768503|Cytophagia 976|Bacteroidetes J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 CMS3_k127_2693857_15 1237149.C900_01062 4.795e-95 314.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,47K3X@768503|Cytophagia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 CMS3_k127_2693857_6 1237149.C900_01063 3.703e-181 570.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,47JD5@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L CMS3_k127_2693857_29 926549.KI421517_gene236 3.561e-60 214.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,47PPE@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 CMS3_k127_2693857_7 1237149.C900_01065 5.385e-176 557.0 COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,47KT4@768503|Cytophagia 976|Bacteroidetes F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CMS3_k127_2693857_5 153721.MYP_1357 6.991e-210 658.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia 976|Bacteroidetes G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N CMS3_k127_2693857_43 1124780.ANNU01000072_gene1067 7.551e-31 123.0 COG2919@1|root,COG2919@2|Bacteria,4P9WW@976|Bacteroidetes,47S83@768503|Cytophagia 976|Bacteroidetes D Septum formation initiator - - - - - - - - - - - - DivIC CMS3_k127_2693857_46 1124780.ANNU01000072_gene1066 1.831e-20 98.0 2DNFQ@1|root,32X9Z@2|Bacteria,4PNNB@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2693857_8 1237149.C900_01069 6.882e-163 518.0 COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47KBZ@768503|Cytophagia 976|Bacteroidetes C Belongs to the LDH2 MDH2 oxidoreductase family - - - - - - - - - - - - Ldh_2 CMS3_k127_2693857_33 1237149.C900_01070 1.825e-55 200.0 COG0248@1|root,COG0248@2|Bacteria,4NH03@976|Bacteroidetes,47K3H@768503|Cytophagia 976|Bacteroidetes FP Ppx GppA phosphatase - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA CMS3_k127_2705413_10 1443665.JACA01000035_gene2353 1.994e-68 237.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HYZH@117743|Flavobacteriia,2YISC@290174|Aquimarina 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_2705413_21 926562.Oweho_2941 8.076e-12 73.0 2E09A@1|root,32VWX@2|Bacteria,4NT9W@976|Bacteroidetes,1I9TI@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2705413_0 1124780.ANNU01000048_gene2129 1.832e-293 921.0 COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec CMS3_k127_2705413_17 391603.FBALC1_09967 3.795e-49 182.0 COG1309@1|root,COG1309@2|Bacteria,4NH7V@976|Bacteroidetes,1HYMJ@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - TetR_C_13,TetR_C_4,TetR_N CMS3_k127_2705413_11 1408433.JHXV01000037_gene2552 2.473e-65 233.0 COG2267@1|root,COG2267@2|Bacteria,4PKB9@976|Bacteroidetes,1IJ6A@117743|Flavobacteriia 976|Bacteroidetes I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4 CMS3_k127_2705413_2 1288963.ADIS_2103 9.124e-167 537.0 COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,47JJT@768503|Cytophagia 976|Bacteroidetes P PFAM Sodium sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp CMS3_k127_2705413_19 1237149.C900_04012 1.711e-27 115.0 2DQ9W@1|root,335IW@2|Bacteria,4NX9R@976|Bacteroidetes,47SCH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2705413_15 1237149.C900_04011 4.354e-53 193.0 COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes,47QAU@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_2705413_9 1237149.C900_05513 1.1e-82 284.0 COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,47K5K@768503|Cytophagia 976|Bacteroidetes G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin CMS3_k127_2705413_5 1237149.C900_03102 2.581e-137 442.0 COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,47N4V@768503|Cytophagia 976|Bacteroidetes I PFAM Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase CMS3_k127_2705413_4 1123277.KB893228_gene2151 1.538e-141 456.0 COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,47K8J@768503|Cytophagia 976|Bacteroidetes H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM CMS3_k127_2705413_18 1121904.ARBP01000018_gene2635 7.049e-38 151.0 COG0725@1|root,COG0725@2|Bacteria,4NYF7@976|Bacteroidetes,47XS0@768503|Cytophagia 976|Bacteroidetes P Bacterial extracellular solute-binding protein - - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 CMS3_k127_2705413_8 1121904.ARBP01000003_gene6254 2.662e-86 290.0 COG4149@1|root,COG4149@2|Bacteria,4NIXK@976|Bacteroidetes,47NHM@768503|Cytophagia 976|Bacteroidetes P PFAM binding-protein-dependent transport systems inner membrane component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 CMS3_k127_2705413_14 926549.KI421517_gene3567 1.203e-53 199.0 COG3842@1|root,COG3842@2|Bacteria,4NK56@976|Bacteroidetes,47MCQ@768503|Cytophagia 976|Bacteroidetes E ATPases associated with a variety of cellular activities - - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran CMS3_k127_2705413_1 1237149.C900_04398 8.938e-248 788.0 COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,47ME6@768503|Cytophagia 976|Bacteroidetes S PFAM Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO CMS3_k127_2705413_16 1107311.Q767_00855 4.585e-50 187.0 COG1861@1|root,COG1861@2|Bacteria,4NPWJ@976|Bacteroidetes,1I2HR@117743|Flavobacteriia 976|Bacteroidetes M Cytidylyltransferase - - 2.7.7.92 ko:K07257,ko:K21750 - - - - ko00000,ko01000 - - - CTP_transf_3 CMS3_k127_2705413_3 1268240.ATFI01000001_gene3515 1.125e-153 492.0 COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,2FPBK@200643|Bacteroidia,4APPP@815|Bacteroidaceae 976|Bacteroidetes M Psort location Cytoplasmic, score 8.96 - - 2.5.1.132 ko:K21279 - - - - ko00000,ko01000 - - - NeuB,SAF CMS3_k127_2705413_13 746697.Aeqsu_2922 3.687e-55 198.0 COG1778@1|root,COG1778@2|Bacteria,4NGXC@976|Bacteroidetes,1HX0H@117743|Flavobacteriia 976|Bacteroidetes M 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family - - 3.1.3.103 ko:K21055 - - R11440 RC00017 ko00000,ko01000 - - - CTP_transf_3,Hydrolase_3 CMS3_k127_2705413_7 1124780.ANNU01000045_gene2331 1.82e-104 357.0 COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,47MXC@768503|Cytophagia 976|Bacteroidetes S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CMS3_k127_2705413_6 1408473.JHXO01000010_gene3756 7.643e-111 368.0 COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,2FNQP@200643|Bacteroidia 976|Bacteroidetes M Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.23 ko:K13019 ko00520,map00520 - R09600 RC00290 ko00000,ko00001,ko01000,ko01005 - - - Epimerase_2 CMS3_k127_2705413_22 1392498.JQLH01000001_gene1602 2.332e-06 52.0 COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,1HWNP@117743|Flavobacteriia,2PG1E@252356|Maribacter 976|Bacteroidetes M glycosyl transferase family 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 CMS3_k127_2752254_5 746697.Aeqsu_2760 1.031e-06 59.0 2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia 976|Bacteroidetes S TIR domain - - - - - - - - - - - - TIR_2 CMS3_k127_2752254_4 1341181.FLJC2902T_19120 2.009e-21 100.0 COG4319@1|root,COG4319@2|Bacteria,4PACD@976|Bacteroidetes,1I8R0@117743|Flavobacteriia,2NXUF@237|Flavobacterium 976|Bacteroidetes S ketosteroid isomerase - - - - - - - - - - - - DUF4440 CMS3_k127_2752254_2 760192.Halhy_5724 3.542e-31 125.0 COG1695@1|root,COG1695@2|Bacteria,4PK5I@976|Bacteroidetes,1IZJS@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Transcriptional regulator PadR N-terminal-like - - - - - - - - - - - - PadR CMS3_k127_2752254_1 1123277.KB893172_gene737 7.36e-128 440.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_2752254_0 1185876.BN8_02202 4.017e-239 754.0 COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes,47N05@768503|Cytophagia 976|Bacteroidetes E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 CMS3_k127_2752254_3 1189612.A33Q_1700 1.206e-26 115.0 2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4920) - - - - - - - - - - - - DUF4920 CMS3_k127_2755928_0 643867.Ftrac_2997 2.453e-233 769.0 COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NRDH@976|Bacteroidetes 976|Bacteroidetes M amine dehydrogenase activity - - - - - - - - - - - - CHU_C,PKD CMS3_k127_277164_7 313595.P700755_001848 1.621e-09 64.0 COG4733@1|root,COG4733@2|Bacteria,4PHUU@976|Bacteroidetes,1HZDA@117743|Flavobacteriia 976|Bacteroidetes G Alpha integrin - - - - - - - - - - - - VCBS CMS3_k127_277164_5 760192.Halhy_3108 2.448e-33 132.0 COG5646@1|root,COG5646@2|Bacteria,4NW3X@976|Bacteroidetes,1IZMU@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 CMS3_k127_277164_0 1250232.JQNJ01000001_gene498 0.0 1564.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia 976|Bacteroidetes G BNR Asp-box repeat - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_277164_3 925409.KI911562_gene2061 8.867e-88 297.0 COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,1IPYQ@117747|Sphingobacteriia 976|Bacteroidetes P ABC-type Fe3 -hydroxamate transport system, periplasmic component fecB - - - - - - - - - - - Peripla_BP_2 CMS3_k127_277164_8 1123276.KB893313_gene3888 3.416e-05 54.0 COG3047@1|root,COG3047@2|Bacteria,4NSNH@976|Bacteroidetes,47R79@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 CMS3_k127_277164_2 643867.Ftrac_2945 2.029e-133 437.0 COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin CMS3_k127_277164_1 1237149.C900_04348 1.564e-171 546.0 COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M80@768503|Cytophagia 976|Bacteroidetes L Belongs to the DEAD box helicase family deaD - - - - - - - - - - - DEAD,Helicase_C CMS3_k127_277164_4 1121104.AQXH01000006_gene2332 2.328e-56 203.0 COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes,1IYDP@117747|Sphingobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_2772921_16 1237149.C900_05121 4.142e-07 59.0 2ECXC@1|root,336UI@2|Bacteria,4NV8T@976|Bacteroidetes,47RWP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2772921_14 643867.Ftrac_0759 6.914e-48 177.0 2CADI@1|root,32RR7@2|Bacteria,4NP51@976|Bacteroidetes,47P8C@768503|Cytophagia 976|Bacteroidetes S Lipopolysaccharide-assembly lptE - - - - - - - - - - - LptE CMS3_k127_2772921_3 1237149.C900_05119 1.767e-180 573.0 COG2204@1|root,COG2204@2|Bacteria,4NDWI@976|Bacteroidetes,47JXW@768503|Cytophagia 976|Bacteroidetes K sigma54 specific, transcriptional regulator, Fis family fhlA - - - - - - - - - - - HTH_8,Sigma54_activat CMS3_k127_2772921_0 1237149.C900_05118 2.242e-230 722.0 COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,47MGS@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 CMS3_k127_2772921_9 1121904.ARBP01000007_gene3145 1.246e-80 272.0 COG0663@1|root,COG0663@2|Bacteria,4NG6R@976|Bacteroidetes,47PIB@768503|Cytophagia 976|Bacteroidetes S carbonic anhydrase acetyltransferase dapH - - - - - - - - - - - Hexapep CMS3_k127_2772921_8 1380600.AUYN01000007_gene3144 1.568e-84 290.0 COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,1HXN8@117743|Flavobacteriia 976|Bacteroidetes P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer CMS3_k127_2772921_4 643867.Ftrac_0746 9.62e-128 414.0 COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes,47KIZ@768503|Cytophagia 976|Bacteroidetes BQ PFAM Histone deacetylase domain - - - - - - - - - - - - Hist_deacetyl CMS3_k127_2772921_10 1124780.ANNU01000023_gene3206 1.219e-75 260.0 COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R3F@768503|Cytophagia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_2772921_7 1237149.C900_03317 2.502e-105 347.0 28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2772921_15 1237149.C900_01259 1.288e-26 116.0 28P8J@1|root,2ZC2G@2|Bacteria,4NTQZ@976|Bacteroidetes,47SAC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2772921_12 1392498.JQLH01000001_gene2550 1.744e-69 245.0 COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,1HX82@117743|Flavobacteriia,2PH4H@252356|Maribacter 976|Bacteroidetes S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos CMS3_k127_2772921_2 1185876.BN8_00887 3.158e-181 596.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MF5@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_2772921_1 926562.Oweho_1631 1.854e-218 688.0 COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia,2PA9J@246874|Cryomorphaceae 976|Bacteroidetes S Carbon-nitrogen hydrolase ramA_2 - - - - - - - - - - - Acetyltransf_1,CN_hydrolase CMS3_k127_2772921_6 743722.Sph21_3435 7.085e-113 377.0 COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1IWYJ@117747|Sphingobacteriia 976|Bacteroidetes S Type I phosphodiesterase / nucleotide pyrophosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phosphodiest CMS3_k127_2772921_11 1237149.C900_04349 1.402e-75 277.0 COG0457@1|root,COG0457@2|Bacteria,4PJN4@976|Bacteroidetes,47NZ0@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_2772921_5 1408433.JHXV01000002_gene281 5.917e-114 378.0 COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,1HX6Z@117743|Flavobacteriia,2PADA@246874|Cryomorphaceae 976|Bacteroidetes I PFAM Fatty acid desaturase - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS3_k127_2772921_13 886377.Murru_3303 2.008e-59 210.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia 976|Bacteroidetes Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 CMS3_k127_2931840_8 1191523.MROS_2518 2.879e-22 104.0 COG1597@1|root,COG1597@2|Bacteria 2|Bacteria I lipid kinase activity - - - - - - - - - - - - DAGK_cat CMS3_k127_2931840_4 471854.Dfer_3742 9.028e-65 231.0 COG4783@1|root,COG4783@2|Bacteria,4NHD8@976|Bacteroidetes,47JAG@768503|Cytophagia 976|Bacteroidetes S chaperone-mediated protein folding - - - - - - - - - - - - TPR_6 CMS3_k127_2931840_5 1492738.FEM21_08610 1.034e-60 216.0 COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia,2NTF8@237|Flavobacterium 976|Bacteroidetes S DinB superfamily yfiT - - - - - - - - - - - DinB_2 CMS3_k127_2931840_3 1237149.C900_00030 3.849e-66 228.0 COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,47QIW@768503|Cytophagia 976|Bacteroidetes E Glyoxalase-like domain - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase CMS3_k127_2931840_6 1237149.C900_02655 3.489e-51 187.0 COG4319@1|root,COG4319@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2911,SnoaL_4 CMS3_k127_2931840_0 1237149.C900_02654 1.919e-259 810.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 CMS3_k127_2931840_2 867900.Celly_0996 8.775e-152 491.0 COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - CMS3_k127_2931840_1 1124780.ANNU01000036_gene34 1.446e-202 642.0 COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,47M9P@768503|Cytophagia 976|Bacteroidetes E Amino acid permease - - - - - - - - - - - - AA_permease CMS3_k127_2936581_2 1347369.CCAD010000015_gene1706 1.054e-72 256.0 COG0654@1|root,COG0654@2|Bacteria,1V6WA@1239|Firmicutes,4IRIJ@91061|Bacilli 91061|Bacilli CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS3_k127_2936581_1 1237149.C900_03740 2.177e-84 291.0 28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,47RCK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2936581_3 1121373.KB903621_gene1857 5.928e-50 182.0 COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,47RNU@768503|Cytophagia 976|Bacteroidetes O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin CMS3_k127_2936581_0 153721.MYP_230 7.875e-113 376.0 COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,47MDG@768503|Cytophagia 976|Bacteroidetes M PFAM 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N CMS3_k127_294609_3 760192.Halhy_1186 2.296e-108 362.0 COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IVTA@117747|Sphingobacteriia 976|Bacteroidetes S COGs COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - 3.5.1.32 ko:K01436,ko:K01451 ko00360,map00360 - R01424 RC00096,RC00162 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_294609_0 1313421.JHBV01000014_gene4038 8.982e-293 914.0 COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase S9, prolyl oligopeptidase, catalytic domain ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N CMS3_k127_294609_4 929562.Emtol_3457 6.15e-98 327.0 COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,47KU9@768503|Cytophagia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - 1.8.3.7 ko:K13444 ko04142,map04142 - - - ko00000,ko00001,ko01000 - - - FGE-sulfatase CMS3_k127_294609_1 1121904.ARBP01000003_gene6277 2.288e-209 661.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase CMS3_k127_294609_2 1230343.CANP01000042_gene3124 1.363e-109 365.0 COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RYK4@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_294609_5 313594.PI23P_08225 4.664e-75 253.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia,3VX9I@52959|Polaribacter 976|Bacteroidetes S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 CMS3_k127_2950666_1 1237149.C900_04701 1.638e-76 262.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_2950666_0 1237149.C900_01608 2.806e-89 302.0 COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_2950666_2 880070.Cycma_0662 4.13e-62 230.0 COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia 976|Bacteroidetes S TIGRFAM ComEC Rec2-related protein comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 CMS3_k127_3038160_1 1121904.ARBP01000018_gene2605 1.232e-220 696.0 COG1960@1|root,COG1960@2|Bacteria,4NEM4@976|Bacteroidetes,47MIF@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA dehydrogenase C-terminal like - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N CMS3_k127_3038160_3 1406840.Q763_07060 1.454e-75 261.0 COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1I0VV@117743|Flavobacteriia,2NUKF@237|Flavobacterium 976|Bacteroidetes Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 CMS3_k127_3038160_2 926549.KI421517_gene2416 1.542e-125 432.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3038160_0 1237149.C900_03499 1.555e-263 847.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NKC3@976|Bacteroidetes,47NP5@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,WD40 CMS3_k127_30733_4 1123008.KB905699_gene1932 3.884e-09 57.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,2FQV3@200643|Bacteroidia,22XNW@171551|Porphyromonadaceae 976|Bacteroidetes K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 CMS3_k127_30733_0 385682.AFSL01000004_gene967 0.0 1144.0 COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,2FNJA@200643|Bacteroidia,3XJ84@558415|Marinilabiliaceae 976|Bacteroidetes P E1-E2 ATPase silP - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase CMS3_k127_30733_2 671143.DAMO_2588 2.422e-158 516.0 COG0543@1|root,COG1413@1|root,COG0543@2|Bacteria,COG1413@2|Bacteria,2NNUA@2323|unclassified Bacteria 2|Bacteria CH Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B pyrK - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 ko:K00266,ko:K00528,ko:K02823 ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248,R10159 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2 CMS3_k127_30733_1 671143.DAMO_2587 1.193e-227 715.0 COG0493@1|root,COG0493@2|Bacteria,2NNXN@2323|unclassified Bacteria 2|Bacteria E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltA - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,Pyr_redox_2 CMS3_k127_30733_3 755732.Fluta_2355 6.206e-27 115.0 2ED7H@1|root,33743@2|Bacteria,4NYV3@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_308727_5 700598.Niako_4472 9.683e-23 98.0 COG0845@1|root,COG0845@2|Bacteria,4NGVX@976|Bacteroidetes,1IQ7U@117747|Sphingobacteriia 976|Bacteroidetes M COGs COG1566 Multidrug resistance efflux pump - - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS3_k127_308727_2 1086011.HJ01_02195 1.697e-113 374.0 COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1HY1P@117743|Flavobacteriia,2NVC3@237|Flavobacterium 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_308727_3 865937.Gilli_0844 1.875e-107 352.0 COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1HWPM@117743|Flavobacteriia,2P5YQ@244698|Gillisia 976|Bacteroidetes V COGs COG1131 ABC-type multidrug transport system ATPase component - - - - - - - - - - - - ABC_tran CMS3_k127_308727_0 1453498.LG45_05070 7.881e-125 409.0 COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia,2NT6W@237|Flavobacterium 976|Bacteroidetes U ABC-2 type transporter ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS3_k127_308727_1 865937.Gilli_0842 4.504e-114 378.0 COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes,1HYPJ@117743|Flavobacteriia 976|Bacteroidetes V Transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS3_k127_308727_4 926549.KI421517_gene2913 3.027e-86 297.0 COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,47M27@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_3099754_13 743722.Sph21_1482 6.769e-18 85.0 COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1IUCP@117747|Sphingobacteriia 976|Bacteroidetes L PFAM Excinuclease ABC, C subunit - - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS3_k127_3099754_11 344747.PM8797T_21828 2.894e-33 139.0 COG1044@1|root,COG2931@1|root,COG4257@1|root,COG1044@2|Bacteria,COG2931@2|Bacteria,COG4257@2|Bacteria 2|Bacteria V antibiotic catabolic process - - 3.4.24.40 ko:K01406,ko:K02414,ko:K07004,ko:K13277,ko:K21449 ko01503,ko02024,ko02040,map01503,map02024,map02040 - - - ko00000,ko00001,ko01000,ko01002,ko02000,ko02035,ko03110 1.B.40.2 - - DUF5011,Peptidase_S55,VCBS CMS3_k127_3099754_14 403833.Pmob_1107 4.737e-16 93.0 COG2234@1|root,COG2234@2|Bacteria,2GCVG@200918|Thermotogae 200918|Thermotogae S Domain of unknown function (DUF4910) - - - - - - - - - - - - Peptidase_M28 CMS3_k127_3099754_1 1086011.HJ01_02215 9.597e-255 794.0 COG2303@1|root,COG2303@2|Bacteria,4NIU5@976|Bacteroidetes,1HZQ2@117743|Flavobacteriia,2NX9D@237|Flavobacterium 976|Bacteroidetes E GMC oxidoreductase - - 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 - R01459 RC00146 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N,NAD_binding_8 CMS3_k127_3099754_8 1223410.KN050846_gene205 2.489e-73 257.0 2DCFR@1|root,2ZDYQ@2|Bacteria,4NPNX@976|Bacteroidetes,1I27F@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4440 CMS3_k127_3099754_10 452637.Oter_1692 7.174e-41 168.0 COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia,3K9Y4@414999|Opitutae 2|Bacteria S PFAM Pyrrolo-quinoline quinone - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PQQ_2,PQQ_3,Pkinase CMS3_k127_3099754_4 655815.ZPR_4168 6.804e-122 407.0 COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia 976|Bacteroidetes P COG0471 Di- and tricarboxylate - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp CMS3_k127_3099754_12 1237149.C900_05618 1.205e-29 119.0 COG0724@1|root,COG0724@2|Bacteria,4NV5J@976|Bacteroidetes,47X4S@768503|Cytophagia 976|Bacteroidetes S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ykfA - - - - - - - - - - - RRM_1 CMS3_k127_3099754_6 761193.Runsl_3687 4.364e-79 280.0 COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_3099754_0 1237149.C900_00062 0.0 1165.0 COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia 976|Bacteroidetes V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran,TerB CMS3_k127_3099754_3 926549.KI421517_gene1812 2.422e-131 427.0 COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,47M4W@768503|Cytophagia 976|Bacteroidetes L SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - Radical_SAM CMS3_k127_3099754_5 1237149.C900_04521 3.245e-85 288.0 COG0745@1|root,COG0745@2|Bacteria,4NM5Q@976|Bacteroidetes,47PED@768503|Cytophagia 976|Bacteroidetes K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_3099754_2 1237149.C900_04522 6.449e-140 456.0 COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47M71@768503|Cytophagia 976|Bacteroidetes T Signal transduction histidine kinase rprX - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_3099754_9 1443665.JACA01000014_gene4459 1.342e-52 194.0 COG4798@1|root,COG4798@2|Bacteria,4NII9@976|Bacteroidetes,1IJX2@117743|Flavobacteriia,2YJ3P@290174|Aquimarina 976|Bacteroidetes S Fibrillarin - - - - - - - - - - - - Methyltransf_12,Methyltransf_25,Methyltransf_31 CMS3_k127_3099754_15 755732.Fluta_1209 6.863e-06 60.0 COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia 976|Bacteroidetes L Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,PKD,Peptidase_M36 CMS3_k127_3099754_7 316067.Geob_1967 4.272e-75 287.0 COG1404@1|root,COG2911@1|root,COG3055@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG3055@2|Bacteria,1QXZF@1224|Proteobacteria 1224|Proteobacteria M family outer membrane protein - - - - - - - - - - - - DUF3739,ESPR,Haemagg_act CMS3_k127_3138013_0 1237149.C900_03344 1.032e-118 399.0 COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47K6V@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag,POTRA CMS3_k127_3138013_3 866536.Belba_2711 4.541e-62 222.0 COG0566@1|root,COG0566@2|Bacteria,4NG1U@976|Bacteroidetes,47NSP@768503|Cytophagia 976|Bacteroidetes J PFAM SpoU rRNA Methylase family aviRb - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind CMS3_k127_3138013_2 927658.AJUM01000046_gene18 1.704e-85 300.0 COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,2G2X9@200643|Bacteroidia,3XJH3@558415|Marinilabiliaceae 976|Bacteroidetes CO Domain of unknown function (DUF4369) - - - - - - - - - - - - AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8 CMS3_k127_3138013_1 1123057.P872_19815 1.889e-112 370.0 COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,47J8X@768503|Cytophagia 976|Bacteroidetes S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage - - - ko:K09125 - - - - ko00000 - - - Vut_1 CMS3_k127_3138013_4 883096.HMPREF9699_01712 1.971e-34 135.0 COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1HXBQ@117743|Flavobacteriia 976|Bacteroidetes S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 CMS3_k127_3143436_12 575590.HMPREF0156_01228 7.372e-14 71.0 COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes 976|Bacteroidetes O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB CMS3_k127_3143436_7 1237149.C900_04098 7.805e-112 366.0 COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia 976|Bacteroidetes M Cell wall-associated hydrolase (invasion-associated protein) ykfC - - - - - - - - - - - NLPC_P60,SH3_3 CMS3_k127_3143436_10 1279009.ADICEAN_00752 7.34e-66 228.0 COG1403@1|root,COG1403@2|Bacteria,4NJ0T@976|Bacteroidetes,47MEF@768503|Cytophagia 976|Bacteroidetes L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 CMS3_k127_3143436_6 761193.Runsl_1977 6.393e-123 408.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,PAS_8 CMS3_k127_3143436_2 1237149.C900_04093 1.803e-229 717.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_3143436_4 1237149.C900_04092 5.085e-182 577.0 COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,47N10@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS3_k127_3143436_5 1237149.C900_04091 4.73e-134 428.0 COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia 976|Bacteroidetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_3143436_1 1237149.C900_05293 5.046e-267 843.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3143436_3 1237149.C900_05644 4.353e-202 655.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47N0R@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3143436_13 313606.M23134_04287 9.381e-07 53.0 COG2197@1|root,COG2197@2|Bacteria,4NMX5@976|Bacteroidetes,47PYR@768503|Cytophagia 976|Bacteroidetes KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg CMS3_k127_3143436_8 1286632.P278_04640 9.84e-94 310.0 COG0500@1|root,COG2226@2|Bacteria,4NYM9@976|Bacteroidetes,1I5IP@117743|Flavobacteriia 976|Bacteroidetes Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 CMS3_k127_3143436_0 1122179.KB890419_gene24 0.0 1260.0 COG4447@1|root,COG4447@2|Bacteria,4NI14@976|Bacteroidetes 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_3143436_14 1461694.ATO9_22530 6.219e-05 47.0 COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,2TXDS@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_3143436_11 1454007.JAUG01000016_gene1745 7.116e-59 210.0 COG4430@1|root,COG4430@2|Bacteria,4NNH0@976|Bacteroidetes,1IXGY@117747|Sphingobacteriia 976|Bacteroidetes S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA CMS3_k127_3143436_9 1250232.JQNJ01000001_gene3478 2.616e-80 279.0 COG4188@1|root,COG4188@2|Bacteria,4NKC2@976|Bacteroidetes,1HZ4A@117743|Flavobacteriia 976|Bacteroidetes S Pkd domain containing protein - - - - - - - - - - - - Chlorophyllase2 CMS3_k127_3146166_20 926549.KI421517_gene1067 7.114e-13 70.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47NYU@768503|Cytophagia 976|Bacteroidetes CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS3_k127_3146166_17 926549.KI421517_gene155 6.156e-50 189.0 COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,47KXV@768503|Cytophagia 976|Bacteroidetes L Helix-hairpin-helix motif comEA - - - - - - - - - - - HHH_3 CMS3_k127_3146166_0 1237149.C900_05507 0.0 1474.0 COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia 976|Bacteroidetes L Superfamily I DNA and RNA - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 CMS3_k127_3146166_5 1121904.ARBP01000053_gene477 3.136e-181 576.0 COG0160@1|root,COG0160@2|Bacteria,4NFWF@976|Bacteroidetes,47XMH@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-III - - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_3146166_9 1454004.AW11_01514 7.417e-130 421.0 COG0388@1|root,COG0388@2|Bacteria,1MY3W@1224|Proteobacteria,2VJ1X@28216|Betaproteobacteria 28216|Betaproteobacteria S Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates amiE - 3.5.1.100,3.5.1.4,3.5.1.49 ko:K01426,ko:K01455,ko:K18540 ko00330,ko00360,ko00380,ko00460,ko00627,ko00630,ko00643,ko00910,ko01120,ko01200,map00330,map00360,map00380,map00460,map00627,map00630,map00643,map00910,map01120,map01200 - R00524,R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025,RC02432,RC02810 ko00000,ko00001,ko01000 - - - CN_hydrolase CMS3_k127_3146166_18 865937.Gilli_0323 3.603e-45 167.0 COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,1I2JA@117743|Flavobacteriia 976|Bacteroidetes S Glyoxalase bleomycin resistance protein dioxygenase - - - ko:K06996 - - - - ko00000 - - - Glyoxalase CMS3_k127_3146166_2 1123234.AUKI01000011_gene1124 0.0 1189.0 COG1982@1|root,COG1982@2|Bacteria,4NHSM@976|Bacteroidetes,1I0X3@117743|Flavobacteriia 976|Bacteroidetes E PFAM Orn Lys Arg decarboxylase, C-terminal domain - - 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C CMS3_k127_3146166_4 1120951.AUBG01000003_gene2783 3.007e-241 756.0 COG0189@1|root,COG0189@2|Bacteria,4PP09@976|Bacteroidetes,1IKCX@117743|Flavobacteriia 976|Bacteroidetes HJ ligase activity - - - - - - - - - - - - - CMS3_k127_3146166_10 1121904.ARBP01000053_gene482 1.204e-113 375.0 COG4927@1|root,COG4927@2|Bacteria,4NGS4@976|Bacteroidetes,47TR3@768503|Cytophagia 976|Bacteroidetes S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - - - - - - - - - - AAT CMS3_k127_3146166_19 1237149.C900_02751 9.527e-33 134.0 2ADSH@1|root,313I2@2|Bacteria,4NQMU@976|Bacteroidetes,47PP1@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated lipoprotein, GldH gldH GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0017144,GO:0040011,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071976,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - GldH_lipo CMS3_k127_3146166_6 1237149.C900_02750 1.367e-179 569.0 COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,47M8P@768503|Cytophagia 976|Bacteroidetes S PFAM PSP1 C-terminal conserved region - - - - - - - - - - - - PSP1 CMS3_k127_3146166_7 1124780.ANNU01000028_gene965 1.86e-162 521.0 COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,47JIA@768503|Cytophagia 976|Bacteroidetes F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N CMS3_k127_3146166_3 1237149.C900_02748 0.0 1103.0 COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,47JD8@768503|Cytophagia 976|Bacteroidetes L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind CMS3_k127_3146166_8 1237149.C900_02747 2.313e-136 440.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,4NED8@976|Bacteroidetes,47KGF@768503|Cytophagia 976|Bacteroidetes M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS CMS3_k127_3146166_11 1237149.C900_02746 1.313e-108 362.0 COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,47KJZ@768503|Cytophagia 976|Bacteroidetes M TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase manC - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CMS3_k127_3146166_13 1237149.C900_02856 2.179e-87 295.0 COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,47JZC@768503|Cytophagia 976|Bacteroidetes J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH - 2.1.1.185 ko:K03218,ko:K03437 - - - - ko00000,ko01000,ko03009,ko03016 - - - SpoU_methylase,SpoU_sub_bind CMS3_k127_3146166_15 1237149.C900_02857 2.849e-67 244.0 28H6U@1|root,2Z7J5@2|Bacteria,4NHUU@976|Bacteroidetes,47JR6@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3146166_12 1237149.C900_02858 6.634e-102 337.0 COG2227@1|root,COG2227@2|Bacteria,4NFHE@976|Bacteroidetes,47JIB@768503|Cytophagia 976|Bacteroidetes H Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_11 CMS3_k127_3146166_1 1237149.C900_02861 0.0 1289.0 COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 CMS3_k127_3146166_16 1237149.C900_02862 4.81e-62 219.0 2C6AJ@1|root,304IU@2|Bacteria,4NPQW@976|Bacteroidetes,47Q1B@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3146166_14 1237149.C900_02863 1.058e-73 254.0 COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,47Y4H@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 CMS3_k127_3150756_1 1237149.C900_04426 1.877e-200 682.0 COG1404@1|root,COG2133@1|root,COG2374@1|root,COG3291@1|root,COG3468@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia 976|Bacteroidetes Q cell adhesion involved in biofilm formation - - - - - - - - - - - - Big_5,PKD CMS3_k127_3150756_0 1121931.AUHG01000016_gene1011 1.322e-276 865.0 COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,1HY3Y@117743|Flavobacteriia 976|Bacteroidetes EH D-isomer specific 2-hydroxyacid dehydrogenase serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,HAD CMS3_k127_3150756_2 1124780.ANNU01000023_gene3216 1.518e-84 290.0 COG0589@1|root,COG0589@2|Bacteria,4NFSG@976|Bacteroidetes,47NF9@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp CMS3_k127_3150756_3 313606.M23134_01718 1.575e-31 124.0 COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_315374_24 316055.RPE_0606 9.09e-08 54.0 COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Benzoyl-CoA reductase subunit - - 1.3.7.8 ko:K04114 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG CMS3_k127_315374_4 316057.RPD_1537 2.396e-176 561.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria 28211|Alphaproteobacteria E benzoyl-CoA reductase - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D CMS3_k127_315374_9 85643.Tmz1t_2951 1.095e-121 402.0 COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales 206389|Rhodocyclales E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D CMS3_k127_315374_20 1121920.AUAU01000006_gene301 2.553e-47 176.0 2BYAB@1|root,32R2Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_315374_19 1189612.A33Q_1181 6.496e-48 185.0 28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - BetR CMS3_k127_315374_16 1121904.ARBP01000003_gene6201 5.262e-80 284.0 COG0204@1|root,COG0204@2|Bacteria,4NK8Z@976|Bacteroidetes,47NT5@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_315374_11 926550.CLDAP_38230 6.206e-111 367.0 COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi 200795|Chloroflexi E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C CMS3_k127_315374_1 643867.Ftrac_1723 0.0 1618.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia 976|Bacteroidetes EF PFAM Carbamoyl-phosphate synthase L chain, ATP binding carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS CMS3_k127_315374_13 1237149.C900_04441 9.765e-95 316.0 COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,47KR3@768503|Cytophagia 976|Bacteroidetes E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase CMS3_k127_315374_0 1237149.C900_04442 0.0 1729.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,47JTE@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW CMS3_k127_315374_22 643867.Ftrac_1757 4.236e-27 116.0 2EJD3@1|root,33D44@2|Bacteria,4NP3M@976|Bacteroidetes,47PW7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - SPOR CMS3_k127_315374_2 1237149.C900_04445 7.482e-218 691.0 COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47N3M@768503|Cytophagia 976|Bacteroidetes P Na+/Pi-cotransporter - - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU CMS3_k127_315374_14 985255.APHJ01000025_gene1086 2.727e-93 321.0 COG3746@1|root,COG3746@2|Bacteria,4NH24@976|Bacteroidetes,1HXMY@117743|Flavobacteriia,2P75P@244698|Gillisia 976|Bacteroidetes P Phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P CMS3_k127_315374_6 1237149.C900_04446 7.484e-141 453.0 COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,47P5H@768503|Cytophagia 976|Bacteroidetes P PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like,PBP_like_2 CMS3_k127_315374_10 153721.MYP_2018 1.802e-111 366.0 COG0573@1|root,COG0573@2|Bacteria,4NFDD@976|Bacteroidetes,47KM7@768503|Cytophagia 976|Bacteroidetes P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CMS3_k127_315374_5 313603.FB2170_04870 6.073e-143 457.0 COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1I16J@117743|Flavobacteriia 976|Bacteroidetes P permease protein PstA pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CMS3_k127_315374_8 1123234.AUKI01000024_gene2115 7.564e-125 404.0 COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1HZHC@117743|Flavobacteriia 976|Bacteroidetes P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran CMS3_k127_315374_18 1107311.Q767_08900 6.404e-58 209.0 COG0704@1|root,COG0704@2|Bacteria,4NNT5@976|Bacteroidetes,1I1UU@117743|Flavobacteriia,2NTDB@237|Flavobacterium 976|Bacteroidetes P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU CMS3_k127_315374_23 1227739.Hsw_4291 4.635e-09 63.0 2DREE@1|root,33BDM@2|Bacteria,4NXHP@976|Bacteroidetes,47SR9@768503|Cytophagia 976|Bacteroidetes S Putative Actinobacterial Holin-X, holin superfamily III - - - - - - - - - - - - Phage_holin_3_6 CMS3_k127_315374_17 1123277.KB893177_gene3551 2.654e-78 269.0 COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia 976|Bacteroidetes I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) pcrB - - ko:K07094 - - - - ko00000,ko01000 - - - PcrB CMS3_k127_315374_7 1089547.KB913013_gene2670 1.603e-134 434.0 COG2207@1|root,COG2207@2|Bacteria,4NFHF@976|Bacteroidetes,47MM1@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_315374_3 1237149.C900_04460 2.354e-211 660.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47JZA@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_315374_12 1237149.C900_04461 2.86e-97 323.0 COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,47MH4@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase, membrane zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 CMS3_k127_315374_15 1237149.C900_04463 3.168e-86 297.0 COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,47JZY@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised protein family (UPF0104) - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM CMS3_k127_315374_21 1121481.AUAS01000006_gene639 3.043e-27 115.0 COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia 976|Bacteroidetes H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase CMS3_k127_3235212_36 649349.Lbys_0096 2.829e-22 97.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia 976|Bacteroidetes M Belongs to the UDP-glucose GDP-mannose dehydrogenase family tuaD - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N CMS3_k127_3235212_5 1237149.C900_03511 3.786e-192 605.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47K4J@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_3235212_37 1237149.C900_03509 9.444e-20 90.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,47RU4@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bS21 family rpsU - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 CMS3_k127_3235212_12 1237149.C900_03508 4.781e-106 351.0 COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,47JJY@768503|Cytophagia 976|Bacteroidetes L Belongs to the 'phage' integrase family xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase CMS3_k127_3235212_35 1121957.ATVL01000006_gene2774 3.974e-24 106.0 COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,47RC7@768503|Cytophagia 976|Bacteroidetes J PFAM Sigma 54 modulation protein S30EA ribosomal protein raiA - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE CMS3_k127_3235212_4 760192.Halhy_4474 3.147e-197 621.0 COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,1INXM@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N CMS3_k127_3235212_24 1189612.A33Q_4372 1.267e-67 237.0 COG0313@1|root,COG0313@2|Bacteria,4NDXE@976|Bacteroidetes,47N4G@768503|Cytophagia 976|Bacteroidetes H PFAM Tetrapyrrole (Corrin Porphyrin) Methylases rsmI_1 - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase CMS3_k127_3235212_38 309799.DICTH_1499 2.503e-15 78.0 2DNS1@1|root,32YVX@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2905) yrzS - - - - - - - - - - - DUF2905 CMS3_k127_3235212_16 1124780.ANNU01000005_gene2378 4.344e-91 306.0 COG0596@1|root,COG0596@2|Bacteria,4NDZI@976|Bacteroidetes,47JB4@768503|Cytophagia 976|Bacteroidetes S Serine aminopeptidase, S33 ybfF - - - - - - - - - - - Abhydrolase_1 CMS3_k127_3235212_13 1237149.C900_02732 3.604e-104 343.0 COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,47K7U@768503|Cytophagia 976|Bacteroidetes H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ CMS3_k127_3235212_31 1048983.EL17_13815 1.264e-45 169.0 COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,47QJ2@768503|Cytophagia 976|Bacteroidetes S PFAM Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY CMS3_k127_3235212_34 643867.Ftrac_1782 2.942e-33 135.0 COG1286@1|root,COG1286@2|Bacteria,4NRG9@976|Bacteroidetes,47S9N@768503|Cytophagia 976|Bacteroidetes S PFAM Colicin V production protein cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V CMS3_k127_3235212_10 1124780.ANNU01000005_gene2383 2.22e-124 402.0 COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,47KEX@768503|Cytophagia 976|Bacteroidetes I alpha/beta hydrolase fold pcbD - - - - - - - - - - - Abhydrolase_1 CMS3_k127_3235212_19 1237149.C900_02727 2.847e-85 288.0 COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,47PRP@768503|Cytophagia 976|Bacteroidetes S PFAM CBS domain - - - - - - - - - - - - CBS CMS3_k127_3235212_11 1237149.C900_02726 1.436e-111 367.0 COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,47KI4@768503|Cytophagia 976|Bacteroidetes G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase CMS3_k127_3235212_15 1237149.C900_02725 5.497e-99 334.0 COG2067@1|root,COG2067@2|Bacteria,4PKQK@976|Bacteroidetes,47XZ1@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - - CMS3_k127_3235212_22 1237149.C900_02724 1.508e-71 248.0 COG3637@1|root,COG3637@2|Bacteria,4NF6B@976|Bacteroidetes,47PKF@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl CMS3_k127_3235212_14 1089547.KB913013_gene2630 1.014e-103 342.0 COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,47MC0@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf CMS3_k127_3235212_0 1237149.C900_02722 0.0 1088.0 COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,47JEC@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein assembly complex, YaeT protein yaeT - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA CMS3_k127_3235212_26 1237149.C900_02721 6.054e-66 230.0 COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,47PD1@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane protein (OmpH-like) skp - - ko:K06142 - - - - ko00000 - - - OmpH CMS3_k127_3235212_30 1237149.C900_02720 7.405e-54 194.0 COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH CMS3_k127_3235212_20 313606.M23134_00271 1.829e-80 278.0 COG1619@1|root,COG1619@2|Bacteria,4NF5Q@976|Bacteroidetes,47KS4@768503|Cytophagia 976|Bacteroidetes V peptidase U61 LD-carboxypeptidase A ykfA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 CMS3_k127_3235212_9 1237149.C900_04691 8.509e-159 510.0 COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,47JQS@768503|Cytophagia 976|Bacteroidetes P TIGRFAM chromate transporter, chromate ion transporter (CHR) family - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp CMS3_k127_3235212_8 1237149.C900_04690 6.061e-164 520.0 COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,47JDX@768503|Cytophagia 976|Bacteroidetes C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N CMS3_k127_3235212_33 1485545.JQLW01000007_gene672 6.976e-38 147.0 2CD0I@1|root,32RWS@2|Bacteria,1N0MC@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF4399) - - - - - - - - - - - - DUF4399 CMS3_k127_3235212_28 1237149.C900_01035 2.162e-55 202.0 COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,47K9Z@768503|Cytophagia 976|Bacteroidetes L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N CMS3_k127_3235212_18 1279009.ADICEAN_01216 1.287e-85 287.0 COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,47JA6@768503|Cytophagia 976|Bacteroidetes F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK CMS3_k127_3235212_27 1237149.C900_01031 9.398e-60 219.0 COG3827@1|root,COG3827@2|Bacteria,4PMMQ@976|Bacteroidetes,47Y53@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3235212_6 643867.Ftrac_2252 6.532e-169 540.0 COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,47JVQ@768503|Cytophagia 976|Bacteroidetes D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE CMS3_k127_3235212_1 1237149.C900_01029 4.62e-229 723.0 COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,47JSM@768503|Cytophagia 976|Bacteroidetes M Penicillin-binding protein, dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase CMS3_k127_3235212_32 1124780.ANNU01000005_gene2405 1.89e-38 149.0 2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,47R21@768503|Cytophagia 976|Bacteroidetes S rod shape-determining protein MreD mreD - - - - - - - - - - - - CMS3_k127_3235212_23 1237149.C900_01027 1.087e-68 242.0 COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,47KWQ@768503|Cytophagia 976|Bacteroidetes M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC CMS3_k127_3235212_3 1237149.C900_01026 4.601e-204 636.0 COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,47JQ4@768503|Cytophagia 976|Bacteroidetes D TIGRFAM cell shape determining protein, MreB Mrl family mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl CMS3_k127_3235212_2 643867.Ftrac_2257 1.093e-216 683.0 COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,47JQT@768503|Cytophagia 976|Bacteroidetes F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS CMS3_k127_3235212_25 1237149.C900_01024 1.318e-66 231.0 COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,47KTP@768503|Cytophagia 976|Bacteroidetes F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N CMS3_k127_3235212_21 1237149.C900_01023 9.148e-76 264.0 COG0382@1|root,COG0382@2|Bacteria,4NGNA@976|Bacteroidetes,47MCK@768503|Cytophagia 976|Bacteroidetes H PFAM UbiA prenyltransferase ubiA - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA CMS3_k127_3235212_17 1237149.C900_02789 3.504e-90 304.0 COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,47MAX@768503|Cytophagia 976|Bacteroidetes S NADP oxidoreductase coenzyme F420-dependent - - - - - - - - - - - - DUF2520,F420_oxidored,Rossmann-like CMS3_k127_3235212_7 760192.Halhy_6306 2.715e-165 530.0 COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_3235212_29 1237149.C900_02790 2.594e-55 197.0 COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia 976|Bacteroidetes O PFAM Cytochrome c assembly protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm CMS3_k127_3254858_2 700598.Niako_1695 2.17e-83 280.0 COG0262@1|root,COG0262@2|Bacteria,4NHIH@976|Bacteroidetes,1J05Q@117747|Sphingobacteriia 976|Bacteroidetes H RibD C-terminal domain - - - - - - - - - - - - RibD_C CMS3_k127_3254858_0 926556.Echvi_3713 5.111e-110 361.0 COG1266@1|root,COG1266@2|Bacteria,4NIKQ@976|Bacteroidetes,47UIE@768503|Cytophagia 976|Bacteroidetes S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CMS3_k127_3254858_8 1120951.AUBG01000006_gene525 2.175e-13 77.0 2E129@1|root,32WI1@2|Bacteria,4NSEA@976|Bacteroidetes,1I4QV@117743|Flavobacteriia 976|Bacteroidetes S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL CMS3_k127_3254858_3 1484460.JSWG01000003_gene769 1.52e-82 274.0 COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1HZR2@117743|Flavobacteriia 976|Bacteroidetes S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt CMS3_k127_3254858_4 760192.Halhy_5493 4.311e-68 235.0 2F17F@1|root,33U8J@2|Bacteria,4P2WT@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3254858_1 1048983.EL17_11305 1.209e-85 293.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia 976|Bacteroidetes K PFAM MerR family regulatory protein - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 CMS3_k127_3254858_5 1279009.ADICEAN_03098 4.111e-48 177.0 COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,47KPZ@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily sigR_3 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_3254858_7 926562.Oweho_3543 2.345e-30 120.0 COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia,2PAX6@246874|Cryomorphaceae 976|Bacteroidetes I NUDIX domain idi - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - NUDIX CMS3_k127_3263234_48 572547.Amico_1287 1.266e-10 72.0 COG0569@1|root,COG0569@2|Bacteria,3T9U5@508458|Synergistetes 508458|Synergistetes C PFAM TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N CMS3_k127_3263234_51 1121481.AUAS01000004_gene1305 0.0001078 52.0 2CH8G@1|root,333J7@2|Bacteria,4NUV3@976|Bacteroidetes,47RYK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3263234_40 471854.Dfer_0082 9.294e-34 139.0 COG5276@1|root,COG5276@2|Bacteria,4NIJE@976|Bacteroidetes,47N1R@768503|Cytophagia 976|Bacteroidetes S LVIVD repeat - - - - - - - - - - - - LVIVD CMS3_k127_3263234_45 1122176.KB903531_gene2915 6.114e-23 105.0 COG5276@1|root,COG5276@2|Bacteria,4NSVQ@976|Bacteroidetes,1IZBC@117747|Sphingobacteriia 976|Bacteroidetes S repeat protein - - - - - - - - - - - - LVIVD CMS3_k127_3263234_39 1235803.C825_00638 6.533e-37 145.0 COG2318@1|root,COG2318@2|Bacteria,4NPTK@976|Bacteroidetes,2FMNC@200643|Bacteroidia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_3263234_47 1267535.KB906767_gene2973 5.914e-13 74.0 2EFWM@1|root,339NX@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_3263234_25 1237149.C900_03863 3.797e-93 311.0 COG3279@1|root,COG3279@2|Bacteria,4NIJQ@976|Bacteroidetes,47XE0@768503|Cytophagia 976|Bacteroidetes K LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_3263234_17 1237149.C900_03864 8.553e-133 432.0 COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,47PMI@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase CMS3_k127_3263234_6 313606.M23134_04993 1.791e-228 732.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47TJP@768503|Cytophagia 976|Bacteroidetes H Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 CMS3_k127_3263234_8 1237149.C900_03865 6.284e-189 612.0 COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,47JA7@768503|Cytophagia 976|Bacteroidetes S oxidoreductase activity - - - - - - - - - - - - - CMS3_k127_3263234_50 1137281.D778_00262 5.926e-08 65.0 COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia 976|Bacteroidetes T Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,TPR_12,TPR_7,TPR_8 CMS3_k127_3263234_1 1189612.A33Q_1947 0.0 1401.0 COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,47JFM@768503|Cytophagia 976|Bacteroidetes O Belongs to the ClpA ClpB family clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR CMS3_k127_3263234_37 313606.M23134_01667 1.242e-45 172.0 COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,47Q4T@768503|Cytophagia 976|Bacteroidetes C PFAM WbqC-like protein family - - - - - - - - - - - - WbqC CMS3_k127_3263234_15 1237149.C900_03871 2.063e-138 448.0 COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,47J93@768503|Cytophagia 976|Bacteroidetes S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG CMS3_k127_3263234_36 1237149.C900_03872 7.143e-48 175.0 COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia 976|Bacteroidetes S TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family ybgC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 CMS3_k127_3263234_27 1237149.C900_03873 1.565e-88 302.0 COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes,47KA8@768503|Cytophagia 976|Bacteroidetes S TIGRFAM YihY family protein (not ribonuclease BN) yfkH - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CMS3_k127_3263234_2 761193.Runsl_3068 0.0 1118.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_3263234_43 118161.KB235922_gene2494 5.153e-24 104.0 COG2329@1|root,COG2329@2|Bacteria,1GFR9@1117|Cyanobacteria 1117|Cyanobacteria S Antibiotic biosynthesis monooxygenase - - 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM CMS3_k127_3263234_3 929556.Solca_2759 0.0 1094.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1IQ80@117747|Sphingobacteriia 976|Bacteroidetes G PFAM Glycosyl hydrolase family 3 C terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14 CMS3_k127_3263234_16 313606.M23134_01800 9.512e-137 440.0 COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47TXK@768503|Cytophagia 976|Bacteroidetes V ATPases associated with a variety of cellular activities gldA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_3263234_24 1408473.JHXO01000016_gene1933 2.527e-93 313.0 COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,2FT12@200643|Bacteroidia 976|Bacteroidetes S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 CMS3_k127_3263234_11 1408473.JHXO01000016_gene1934 6.158e-162 524.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,2FR8P@200643|Bacteroidia 976|Bacteroidetes N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux CMS3_k127_3263234_38 866536.Belba_1358 1.964e-43 163.0 COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,47R4H@768503|Cytophagia 976|Bacteroidetes L PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain ogt - 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 CMS3_k127_3263234_18 118173.KB235910_gene4738 3.704e-131 426.0 COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1H82U@1150|Oscillatoriales 1117|Cyanobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh CMS3_k127_3263234_0 98439.AJLL01000072_gene1223 0.0 1587.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1G2E2@1117|Cyanobacteria 1117|Cyanobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C CMS3_k127_3263234_46 1047013.AQSP01000110_gene56 6.705e-16 93.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarboxypepD_reg CMS3_k127_3263234_7 1237149.C900_00992 2.632e-215 677.0 COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_3263234_41 643867.Ftrac_2952 1.604e-31 125.0 COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,47R8K@768503|Cytophagia 976|Bacteroidetes S PFAM ATP-dependent Clp protease adaptor protein ClpS clpS - - ko:K06891 - - - - ko00000 - - - ClpS CMS3_k127_3263234_28 1120965.AUBV01000008_gene2003 9.96e-81 273.0 COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,47JZK@768503|Cytophagia 976|Bacteroidetes L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 CMS3_k127_3263234_10 1237149.C900_00995 9.894e-168 537.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,47JJH@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_3263234_22 929556.Solca_2092 1.726e-100 337.0 COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,1IQQ3@117747|Sphingobacteriia 976|Bacteroidetes M Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose rfaE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB CMS3_k127_3263234_13 1237149.C900_03234 1.499e-142 457.0 COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,47JRY@768503|Cytophagia 976|Bacteroidetes E PFAM Serine dehydratase alpha chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha CMS3_k127_3263234_31 1168289.AJKI01000040_gene3228 2.696e-66 232.0 COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia,3XIJS@558415|Marinilabiliaceae 976|Bacteroidetes F Uracil phosphoribosyltransferase upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase CMS3_k127_3263234_19 1237149.C900_03238 1.289e-130 423.0 COG1363@1|root,COG1363@2|Bacteria,4NH34@976|Bacteroidetes,47MR1@768503|Cytophagia 976|Bacteroidetes G PFAM M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 CMS3_k127_3263234_33 1237149.C900_03239 1.186e-62 219.0 COG0634@1|root,COG0634@2|Bacteria,4NNIB@976|Bacteroidetes,47PQ9@768503|Cytophagia 976|Bacteroidetes F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran CMS3_k127_3263234_29 1120968.AUBX01000014_gene2640 4.029e-80 271.0 COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,47NHN@768503|Cytophagia 976|Bacteroidetes F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,Pribosyltran CMS3_k127_3263234_12 1279009.ADICEAN_03111 6.155e-155 494.0 COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes,47JCS@768503|Cytophagia 976|Bacteroidetes S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 CMS3_k127_3263234_35 1237149.C900_03242 3.827e-48 179.0 COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,47QCT@768503|Cytophagia 976|Bacteroidetes O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE CMS3_k127_3263234_9 1237149.C900_03243 7.424e-177 560.0 COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,47MD9@768503|Cytophagia 976|Bacteroidetes O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CMS3_k127_3263234_26 1237149.C900_03244 7.801e-89 302.0 2BK1P@1|root,32EEX@2|Bacteria,4NRXN@976|Bacteroidetes,47QMH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3263234_21 1185876.BN8_01667 1.472e-124 407.0 COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,47KYF@768503|Cytophagia 976|Bacteroidetes S PFAM ABC transporter natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 CMS3_k127_3263234_20 1124780.ANNU01000042_gene641 1.155e-129 427.0 COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia 976|Bacteroidetes CP COGs COG1668 ABC-type Na efflux pump permease component natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS3_k127_3263234_14 1237149.C900_03247 5.547e-141 458.0 COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,47Y3V@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase vicK - - - - - - - - - - - HATPase_c CMS3_k127_3263234_5 1237149.C900_03248 3.33e-280 865.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,47KRX@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N CMS3_k127_3263234_42 1048983.EL17_14635 2.466e-24 104.0 COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,47S1U@768503|Cytophagia 976|Bacteroidetes C PFAM ATP synthase, Delta Epsilon chain, beta-sandwich domain atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N CMS3_k127_3263234_44 1237149.C900_03250 2.136e-23 103.0 2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,47RYW@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3263234_30 1124780.ANNU01000042_gene647 4.097e-73 253.0 COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,47KV5@768503|Cytophagia 976|Bacteroidetes J Pseudouridine synthase rluC - 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 CMS3_k127_3263234_4 643867.Ftrac_1865 0.0 1054.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia 976|Bacteroidetes O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 CMS3_k127_3263234_32 1121904.ARBP01000010_gene2401 1.02e-63 232.0 COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,47RSW@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_3263234_23 926562.Oweho_0337 1.954e-97 328.0 COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia 976|Bacteroidetes S Sodium bile acid symporter family - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF CMS3_k127_3263234_34 1121875.KB907549_gene1942 1.022e-59 215.0 COG2135@1|root,COG2135@2|Bacteria,4NI3T@976|Bacteroidetes,1HWW1@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP CMS3_k127_331141_1 1237149.C900_03999 7.991e-159 532.0 COG0457@1|root,COG0457@2|Bacteria,4NGQ7@976|Bacteroidetes,47KHQ@768503|Cytophagia 976|Bacteroidetes U Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 CMS3_k127_331141_4 1237149.C900_05489 6.628e-121 391.0 COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,47KDU@768503|Cytophagia 976|Bacteroidetes V ABC transporter macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_331141_5 1237149.C900_05490 1.439e-66 231.0 COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,47P8Y@768503|Cytophagia 976|Bacteroidetes S PFAM Cobalamin adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans CMS3_k127_331141_0 643867.Ftrac_0939 1.232e-167 533.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,47M72@768503|Cytophagia 976|Bacteroidetes EH Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 CMS3_k127_331141_7 880071.Fleli_3904 3.033e-05 53.0 291FA@1|root,2ZP24@2|Bacteria,4P8QY@976|Bacteroidetes,47WH6@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_331141_2 1279009.ADICEAN_03248 7.292e-154 492.0 COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes,47KHU@768503|Cytophagia 976|Bacteroidetes J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 CMS3_k127_331141_3 1237149.C900_05494 1.559e-147 477.0 COG0477@1|root,COG2814@2|Bacteria,4NE7F@976|Bacteroidetes,47MD0@768503|Cytophagia 976|Bacteroidetes EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr CMS3_k127_331141_6 1035193.HMPREF9073_00051 2.609e-05 49.0 COG3179@1|root,COG3179@2|Bacteria,4NF8K@976|Bacteroidetes,1HYFJ@117743|Flavobacteriia,1ER1T@1016|Capnocytophaga 976|Bacteroidetes S fibronectin type III domain protein - - - - - - - - - - - - fn3 CMS3_k127_3316598_2 1122621.ATZA01000016_gene3761 2.998e-44 164.0 COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1IT1Y@117747|Sphingobacteriia 976|Bacteroidetes O TIGRFAM Peroxiredoxin, osmotically inducible protein C, subgroup - - - ko:K04063 - - - - ko00000 - - - OsmC CMS3_k127_3316598_0 637905.SVI_0852 3.047e-110 368.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,1RNUU@1236|Gammaproteobacteria,2QATR@267890|Shewanellaceae 1236|Gammaproteobacteria EGP COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_3316598_4 487796.Flav2ADRAFT_0926 2.714e-35 144.0 2C3TU@1|root,2ZBKB@2|Bacteria,4NMMF@976|Bacteroidetes,1I1HI@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3316598_1 1237149.C900_03317 1.673e-61 221.0 28KF8@1|root,2ZA1G@2|Bacteria,4NK7X@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3316598_3 1223410.KN050846_gene2423 1.03e-35 138.0 COG2159@1|root,COG2159@2|Bacteria,4NK6T@976|Bacteroidetes,1I2BN@117743|Flavobacteriia 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_3324601_10 1349785.BAUG01000004_gene376 3.355e-42 159.0 COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1I2EF@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_3324601_12 1268237.G114_18986 2.285e-07 57.0 2E6HR@1|root,33150@2|Bacteria 2|Bacteria S YCII-related domain - - - - - - - - - - - - YCII CMS3_k127_3324601_7 1237149.C900_02657 1.475e-49 179.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - CMS3_k127_3324601_9 1237149.C900_02658 6.01e-44 168.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47RJQ@768503|Cytophagia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_3324601_2 926562.Oweho_2547 3.293e-138 457.0 COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia,2PBDE@246874|Cryomorphaceae 976|Bacteroidetes O Peptidase family M28 - - - - - - - - - - - - PD40,PDZ_2,Peptidase_M28 CMS3_k127_3324601_0 518766.Rmar_2521 2.287e-187 600.0 COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1FKC5@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 CMS3_k127_3324601_11 1408473.JHXO01000005_gene1683 2.356e-17 83.0 COG1983@1|root,COG1983@2|Bacteria,4NX1N@976|Bacteroidetes,2FUW2@200643|Bacteroidia 976|Bacteroidetes KT PspC domain protein - - - - - - - - - - - - PspC CMS3_k127_3324601_5 1237149.C900_05163 6.587e-58 216.0 COG0484@1|root,COG4783@1|root,COG0484@2|Bacteria,COG4783@2|Bacteria 2|Bacteria L chaperone-mediated protein folding - - - ko:K21010 ko02025,map02025 - - - ko00000,ko00001 - - - DUF560,DnaJ,Dynamin_N,Peptidase_M48,TPR_19,TPR_8 CMS3_k127_3324601_1 1121904.ARBP01000028_gene1668 4.303e-152 488.0 COG2041@1|root,COG2041@2|Bacteria,4NHQB@976|Bacteroidetes,47MUT@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase molybdopterin binding domain - - - - - - - - - - - - Oxidored_molyb CMS3_k127_3324601_4 388413.ALPR1_05490 8.983e-94 321.0 COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 CMS3_k127_3324601_8 743722.Sph21_0232 1.844e-48 176.0 COG0394@1|root,COG0394@2|Bacteria,4NNN6@976|Bacteroidetes,1IS9S@117747|Sphingobacteriia 976|Bacteroidetes T Low molecular weight phosphotyrosine protein phosphatase arsC - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc CMS3_k127_3324601_6 1443665.JACA01000013_gene4163 2.484e-57 204.0 COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,1I246@117743|Flavobacteriia,2YHRD@290174|Aquimarina 976|Bacteroidetes M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 CMS3_k127_3324601_3 1237149.C900_00736 2.57e-100 334.0 COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,47NAG@768503|Cytophagia 976|Bacteroidetes J PFAM Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans CMS3_k127_3324601_13 760192.Halhy_3394 1.401e-05 47.0 COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,1IXJ7@117747|Sphingobacteriia 976|Bacteroidetes J PFAM SpoU rRNA Methylase family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind CMS3_k127_3337305_28 1123057.P872_23375 2.632e-07 52.0 28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,47MBS@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2480) - - - - - - - - - - - - DUF2480 CMS3_k127_3337305_16 1124780.ANNU01000090_gene322 3.928e-61 219.0 COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,47NST@768503|Cytophagia 976|Bacteroidetes O TIGRFAM universal bacterial protein YeaZ yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 CMS3_k127_3337305_7 153721.MYP_2127 7.303e-183 587.0 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 CMS3_k127_3337305_26 1237149.C900_04943 5.374e-18 89.0 COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,47S3A@768503|Cytophagia 976|Bacteroidetes J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P CMS3_k127_3337305_25 435590.BVU_0530 4.489e-18 84.0 COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,2FUJ7@200643|Bacteroidia,4AS4R@815|Bacteroidaceae 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 CMS3_k127_3337305_8 1121904.ARBP01000012_gene1361 6.001e-171 549.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47N92@768503|Cytophagia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_3337305_0 1237149.C900_04427 5.034e-266 841.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47UBY@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3337305_29 981383.AEWH01000041_gene3579 0.0006909 51.0 COG3212@1|root,COG3212@2|Bacteria,1VEU1@1239|Firmicutes 1239|Firmicutes S Peptidase propeptide and YPEB domain protein ykoJ - - - - - - - - - - - PepSY CMS3_k127_3337305_27 945713.IALB_2436 1.916e-10 72.0 COG3212@1|root,COG3212@2|Bacteria 2|Bacteria T peptidase ykoI - - - - - - - - - - - PepSY CMS3_k127_3337305_24 1121875.KB907547_gene3151 1.754e-22 101.0 2CWXQ@1|root,32T0K@2|Bacteria,4NTPX@976|Bacteroidetes,1I9XX@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3337305_9 313603.FB2170_07914 3.274e-162 523.0 COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1HYY8@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M CMS3_k127_3337305_4 742725.HMPREF9450_00518 1.607e-200 635.0 COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,2FNXD@200643|Bacteroidia 976|Bacteroidetes C proton-translocating NADH-quinone oxidoreductase, chain M nuoM - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M CMS3_k127_3337305_2 313603.FB2170_07924 9.51e-238 750.0 COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1HWXX@117743|Flavobacteriia 976|Bacteroidetes CP NADH ubiquinone oxidoreductase subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N CMS3_k127_3337305_21 700598.Niako_7218 1.372e-35 138.0 COG0713@1|root,COG0713@2|Bacteria,4NSR8@976|Bacteroidetes,1ITB0@117747|Sphingobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 CMS3_k127_3337305_19 313603.FB2170_07934 1.301e-37 147.0 COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I26W@117743|Flavobacteriia 976|Bacteroidetes C Belongs to the complex I subunit 6 family nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 CMS3_k127_3337305_15 1121875.KB907547_gene3145 7.645e-67 230.0 COG1143@1|root,COG1143@2|Bacteria,4NI9I@976|Bacteroidetes,1I6VR@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 CMS3_k127_3337305_10 700598.Niako_7215 1.85e-153 492.0 COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1INP9@117747|Sphingobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh CMS3_k127_3337305_5 313603.FB2170_07949 2.048e-194 611.0 COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases CMS3_k127_3337305_17 1121875.KB907547_gene3142 9.08e-49 180.0 COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa CMS3_k127_3337305_13 1121875.KB907547_gene3141 3.264e-84 284.0 COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 CMS3_k127_3337305_11 886379.AEWI01000078_gene1974 1.22e-137 445.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,3XJPN@558415|Marinilabiliaceae 976|Bacteroidetes C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain oorB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C CMS3_k127_3337305_1 742817.HMPREF9449_02657 3.616e-253 794.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,22WBU@171551|Porphyromonadaceae 976|Bacteroidetes C 2-oxoacid acceptor oxidoreductase, alpha subunit porA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N CMS3_k127_3337305_22 485913.Krac_11134 1.042e-29 120.0 COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_4 CMS3_k127_3337305_23 1047013.AQSP01000131_gene1797 4.084e-25 113.0 COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria 2|Bacteria U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 CMS3_k127_3337305_20 1317122.ATO12_15635 4.487e-36 147.0 2C312@1|root,2Z7N1@2|Bacteria,4NFNW@976|Bacteroidetes,1I541@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3337305_18 1121904.ARBP01000001_gene5629 2.497e-47 180.0 29D4N@1|root,3002P@2|Bacteria,4NPSH@976|Bacteroidetes,47Q5V@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_3337305_3 1121904.ARBP01000001_gene5628 4.109e-214 690.0 COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,47N17@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3337305_14 935863.AWZR01000001_gene1972 2.009e-79 275.0 COG5504@1|root,COG5504@2|Bacteria,1RCGT@1224|Proteobacteria,1SXX1@1236|Gammaproteobacteria,1X6Y0@135614|Xanthomonadales 135614|Xanthomonadales O Predicted Zn-dependent protease (DUF2268) - - - - - - - - - - - - DUF2268 CMS3_k127_3337305_6 1237149.C900_03921 1.623e-191 624.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47MUU@768503|Cytophagia 976|Bacteroidetes H Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 CMS3_k127_3337305_12 880073.Calab_2443 4.51e-102 342.0 COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria 2|Bacteria C PFAM Alcohol dehydrogenase, zinc-binding - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N CMS3_k127_3351134_9 153721.MYP_2511 4.616e-15 76.0 2ECIG@1|root,33HGA@2|Bacteria,4NXUX@976|Bacteroidetes,47T4J@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3351134_2 760192.Halhy_6089 4.164e-113 383.0 COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia 2|Bacteria MU Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_3351134_6 1237149.C900_01631 1.201e-46 170.0 COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,47S1E@768503|Cytophagia 976|Bacteroidetes L Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 CMS3_k127_3351134_1 1237149.C900_03398 5.41e-160 516.0 COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_3351134_0 880073.Calab_2205 4.869e-167 537.0 COG1488@1|root,COG1488@2|Bacteria,2NNUE@2323|unclassified Bacteria 2|Bacteria H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase CMS3_k127_3351134_5 926559.JoomaDRAFT_1396 1.507e-65 228.0 COG1335@1|root,COG1335@2|Bacteria,4NKPP@976|Bacteroidetes,1HZKC@117743|Flavobacteriia 976|Bacteroidetes Q Isochorismatase family pncA - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase CMS3_k127_3351134_3 153721.MYP_1717 2.608e-104 347.0 COG1131@1|root,COG1131@2|Bacteria,4NMN9@976|Bacteroidetes,47VAE@768503|Cytophagia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_3351134_4 1408473.JHXO01000012_gene317 1.485e-100 338.0 COG0842@1|root,COG0842@2|Bacteria,4NKB0@976|Bacteroidetes,2FW5E@200643|Bacteroidia 976|Bacteroidetes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 CMS3_k127_3351134_7 267377.MMP0827 1.578e-27 115.0 arCOG03453@1|root,arCOG03453@2157|Archaea,2Y50E@28890|Euryarchaeota,23RRD@183939|Methanococci 183939|Methanococci - - - - - - - - - - - - - - - CMS3_k127_3351134_8 309807.SRU_2321 4.717e-23 110.0 2DMY6@1|root,32UCD@2|Bacteria,4NVHX@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_337647_4 1123388.AQWU01000053_gene1547 1.378e-10 69.0 COG2329@1|root,COG2329@2|Bacteria,1WNCW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM CMS3_k127_337647_0 1237149.C900_03496 3.175e-114 384.0 COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia 976|Bacteroidetes S MORN repeat variant - - - - - - - - - - - - MORN_2,TPR_1,TPR_16,TPR_8 CMS3_k127_337647_3 929703.KE386491_gene3244 9.578e-43 162.0 COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_337647_1 1121904.ARBP01000001_gene5706 2.159e-104 360.0 COG2885@1|root,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - PD40 CMS3_k127_337647_2 1237149.C900_02737 4.3e-44 169.0 COG3595@1|root,COG3595@2|Bacteria,4NR7Q@976|Bacteroidetes,47XVG@768503|Cytophagia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_3386630_25 1536775.H70737_13595 1.129e-10 65.0 COG0454@1|root,COG0456@2|Bacteria,1VGQ7@1239|Firmicutes,4HQF4@91061|Bacilli,277JP@186822|Paenibacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_3386630_6 313596.RB2501_12302 9.059e-158 523.0 COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes,1HZ27@117743|Flavobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_3386630_12 1121904.ARBP01000011_gene1562 2.241e-97 324.0 COG2220@1|root,COG2220@2|Bacteria,4NFJ4@976|Bacteroidetes,47JCF@768503|Cytophagia 976|Bacteroidetes S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 CMS3_k127_3386630_13 1123057.P872_16580 1.238e-95 320.0 COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,47JVW@768503|Cytophagia 976|Bacteroidetes S phenazine biosynthesis protein PhzF family - - - - - - - - - - - - PhzC-PhzF CMS3_k127_3386630_24 1356852.N008_15760 1.039e-12 75.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - CMS3_k127_3386630_23 926549.KI421517_gene1364 2.33e-14 79.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - CMS3_k127_3386630_15 1406840.Q763_09675 2.049e-54 195.0 COG2318@1|root,COG2318@2|Bacteria,4NMXH@976|Bacteroidetes,1I32M@117743|Flavobacteriia 976|Bacteroidetes S Damage-inducible protein DinB - - - - - - - - - - - - DinB_2 CMS3_k127_3386630_20 504472.Slin_0933 5.569e-30 121.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QZJ@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_3386630_7 1123277.KB893174_gene5903 2.735e-156 524.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3386630_1 643867.Ftrac_1697 6.772e-190 601.0 COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,47K6M@768503|Cytophagia 976|Bacteroidetes S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 CMS3_k127_3386630_18 1288963.ADIS_1753 7.847e-45 170.0 COG3091@1|root,COG3091@2|Bacteria,4NDXX@976|Bacteroidetes,47QAA@768503|Cytophagia 976|Bacteroidetes S PFAM SprT-like family sprT - - - - - - - - - - - SprT-like CMS3_k127_3386630_11 1237149.C900_01165 6.293e-136 437.0 COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,47K6T@768503|Cytophagia 976|Bacteroidetes G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS CMS3_k127_3386630_14 1237149.C900_01166 4.47e-95 319.0 COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia 976|Bacteroidetes G N-acetylglucosamine kinase - - - - - - - - - - - - BcrAD_BadFG CMS3_k127_3386630_19 1237149.C900_01168 2.996e-32 127.0 COG4892@1|root,COG4892@2|Bacteria,4NSAM@976|Bacteroidetes,47R83@768503|Cytophagia 976|Bacteroidetes S PFAM Cytochrome b5-like Heme Steroid binding domain - - - - - - - - - - - - Cyt-b5 CMS3_k127_3386630_4 1121904.ARBP01000010_gene2354 7.183e-160 513.0 COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia 976|Bacteroidetes E PFAM Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 CMS3_k127_3386630_21 1237149.C900_04437 3.854e-28 119.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus - - 2.8.1.1,2.8.1.2 ko:K01011,ko:K06867 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Ank_2,Ank_3,Ank_4,Ank_5,Rhodanese CMS3_k127_3386630_9 1237149.C900_04438 1.99e-148 500.0 COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NGJJ@976|Bacteroidetes,47KNC@768503|Cytophagia 976|Bacteroidetes S Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_3386630_26 313595.P700755_000309 5.951e-06 60.0 COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,4C2CH@83612|Psychroflexus 976|Bacteroidetes O Metallo-peptidase family M12 - - - - - - - - - - - - P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5 CMS3_k127_3386630_3 1237149.C900_01796 2.318e-179 569.0 COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,47JES@768503|Cytophagia 976|Bacteroidetes E Belongs to the arginase family - - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase CMS3_k127_3386630_0 1124780.ANNU01000051_gene2071 1.455e-251 779.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway nqrF - 1.6.5.8 ko:K00351 - - - - ko00000,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 CMS3_k127_3386630_8 1166018.FAES_0905 7.698e-155 494.0 COG0535@1|root,COG0535@2|Bacteria,4NJ4D@976|Bacteroidetes,47K2Y@768503|Cytophagia 976|Bacteroidetes S 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM CMS3_k127_3386630_10 1237149.C900_00475 6.251e-148 471.0 COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,47JX2@768503|Cytophagia 976|Bacteroidetes I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS3_k127_3386630_2 1313301.AUGC01000010_gene956 2.439e-189 595.0 COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes 976|Bacteroidetes G Aldolase fbaB - 4.1.2.13 ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - DeoC CMS3_k127_3386630_16 1124780.ANNU01000052_gene3579 1.371e-52 187.0 COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,47QAS@768503|Cytophagia 976|Bacteroidetes J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 CMS3_k127_3386630_5 313606.M23134_05036 5.719e-159 518.0 COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47NEB@768503|Cytophagia 976|Bacteroidetes P Na+/Pi-cotransporter - - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans CMS3_k127_3386630_17 1237149.C900_04548 1.036e-49 186.0 COG4758@1|root,COG4758@2|Bacteria,4NQRE@976|Bacteroidetes,47R3Y@768503|Cytophagia 976|Bacteroidetes S Cell wall-active antibiotics response 4TMS YvqF - - - - - - - - - - - - DUF2154 CMS3_k127_3389695_0 1121875.KB907549_gene1707 8.465e-171 558.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_3398781_0 1237149.C900_02615 0.0 1572.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_3398781_1 1392489.JPOL01000002_gene503 2.865e-309 962.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia,2XK11@283735|Leeuwenhoekiella 976|Bacteroidetes S Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer CMS3_k127_3398781_3 1237149.C900_02617 6.093e-190 599.0 COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia 976|Bacteroidetes E PFAM Cys Met metabolism PLP-dependent enzyme metC - 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP CMS3_k127_3398781_4 1047013.AQSP01000100_gene588 1.136e-96 327.0 COG3949@1|root,COG3949@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_3398781_6 864702.OsccyDRAFT_1016 1.891e-10 63.0 COG5002@1|root,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3 CMS3_k127_3398781_5 1121904.ARBP01000008_gene3224 3.212e-22 100.0 COG0784@1|root,COG0784@2|Bacteria,4NSX5@976|Bacteroidetes,47QFR@768503|Cytophagia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_3398781_7 485918.Cpin_4971 5.295e-08 57.0 COG0784@1|root,COG0784@2|Bacteria,4NSX5@976|Bacteroidetes,1IZ5I@117747|Sphingobacteriia 976|Bacteroidetes T PFAM response regulator receiver - - - - - - - - - - - - Response_reg CMS3_k127_3398781_2 1237149.C900_02605 5.762e-196 642.0 COG1520@1|root,COG1520@2|Bacteria,4NHQ3@976|Bacteroidetes,47MS3@768503|Cytophagia 976|Bacteroidetes S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - DUF3352 CMS3_k127_3404497_2 742817.HMPREF9449_02821 2.003e-226 723.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,22W91@171551|Porphyromonadaceae 976|Bacteroidetes P CarboxypepD_reg-like domain susC - - ko:K21573 - - - - ko00000,ko02000 1.B.14.6.1 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3404497_3 1122176.KB903536_gene1756 9.998e-212 666.0 COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1IPIA@117747|Sphingobacteriia 976|Bacteroidetes G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 CMS3_k127_3404497_4 1191523.MROS_2200 1.386e-151 492.0 COG0366@1|root,COG0366@2|Bacteria 2|Bacteria G hydrolase activity, hydrolyzing O-glycosyl compounds amyB - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C CMS3_k127_3404497_0 1237149.C900_04352 6.353e-301 944.0 COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31 CMS3_k127_3404497_6 1237149.C900_02568 3.188e-127 416.0 COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MGC@768503|Cytophagia 976|Bacteroidetes K PFAM Periplasmic binding protein LacI transcriptional regulator cytR - - ko:K02529,ko:K05499 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CMS3_k127_3404497_8 1101195.Meth11DRAFT_2482 1.273e-110 376.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VQSY@28216|Betaproteobacteria 28216|Betaproteobacteria CH PFAM monooxygenase FAD-binding pcpB - 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS3_k127_3404497_12 1237149.C900_05727 1.174e-42 164.0 28P2C@1|root,2ZBYG@2|Bacteria,4NMEQ@976|Bacteroidetes,47PKX@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3404497_7 493475.GARC_4579 6.554e-124 410.0 COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,1RPEJ@1236|Gammaproteobacteria,46CRA@72275|Alteromonadaceae 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_3404497_10 401053.AciPR4_2596 2.162e-88 317.0 COG1363@1|root,COG1363@2|Bacteria,3Y2Y3@57723|Acidobacteria,2JKCI@204432|Acidobacteriia 204432|Acidobacteriia G PFAM M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 CMS3_k127_3404497_9 926554.KI912640_gene1366 1.208e-94 322.0 COG1960@1|root,COG1960@2|Bacteria,1WMGQ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_3404497_15 653948.CCA17626 3.428e-09 66.0 KOG4064@1|root,KOG4064@2759|Eukaryota 2759|Eukaryota C alkanesulfonate biosynthetic process CDO1 GO:0000096,GO:0000097,GO:0000098,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006534,GO:0006790,GO:0006805,GO:0006807,GO:0006810,GO:0006950,GO:0006952,GO:0006954,GO:0007275,GO:0007589,GO:0007595,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009410,GO:0009636,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017172,GO:0019448,GO:0019450,GO:0019451,GO:0019452,GO:0019530,GO:0019694,GO:0019752,GO:0030879,GO:0031960,GO:0032501,GO:0032502,GO:0032787,GO:0033762,GO:0033993,GO:0042221,GO:0042412,GO:0042493,GO:0043167,GO:0043169,GO:0043200,GO:0043434,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045471,GO:0046305,GO:0046394,GO:0046395,GO:0046439,GO:0046677,GO:0046683,GO:0046872,GO:0046903,GO:0046914,GO:0048513,GO:0048545,GO:0048731,GO:0048732,GO:0048856,GO:0050878,GO:0050896,GO:0051179,GO:0051213,GO:0051234,GO:0051384,GO:0051591,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0097305,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901652,GO:1901698,GO:1901700 1.13.11.20,2.3.2.27 ko:K00456,ko:K05012,ko:K15711 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000,ko03400,ko04040,ko04121 2.A.49.1.1,2.A.49.1.2,2.A.49.1.3,2.A.49.2.2,2.A.49.2.3,2.A.49.2.8 - iRC1080.CRv4_Au5_s3_g10641_t1 CDO_I CMS3_k127_3404497_11 1403819.BATR01000133_gene4702 2.37e-74 260.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator exsA GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1903506,GO:2000112,GO:2001141 - ko:K20968 ko02025,map02025 - - - ko00000,ko00001,ko03000 - - - HTH_18 CMS3_k127_3404497_13 1077972.ARGLB_073_00250 1.05e-25 109.0 29X4H@1|root,30ITE@2|Bacteria,2GYF3@201174|Actinobacteria 201174|Actinobacteria S YCII-related domain - - - - - - - - - - - - YCII CMS3_k127_3404497_1 1121904.ARBP01000015_gene179 7.014e-253 803.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3404497_5 1189612.A33Q_1470 9.523e-129 420.0 COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47JKN@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - Beta-lactamase CMS3_k127_346084_0 1237149.C900_05256 4.904e-315 981.0 COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia 976|Bacteroidetes V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran,TerB CMS3_k127_346084_1 1237149.C900_05257 9.38e-57 203.0 29N3N@1|root,33SHJ@2|Bacteria,4P1XQ@976|Bacteroidetes,47TMQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3507578_3 1121904.ARBP01000009_gene4352 3.599e-51 183.0 COG3682@1|root,COG3682@2|Bacteria,4NT4V@976|Bacteroidetes,47R2Y@768503|Cytophagia 976|Bacteroidetes K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R CMS3_k127_3507578_0 1121904.ARBP01000009_gene4351 3.641e-156 502.0 COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,4NW2E@976|Bacteroidetes,47YB7@768503|Cytophagia 976|Bacteroidetes M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - Peptidase_M56,TonB_C CMS3_k127_3507578_1 468059.AUHA01000003_gene1783 7.241e-126 413.0 COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1IQ64@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Cys Met metabolism PLP-dependent enzyme metC - 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP CMS3_k127_3507578_2 1123057.P872_21265 1.61e-118 390.0 COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47UNC@768503|Cytophagia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - CMS3_k127_3507578_4 1123057.P872_21260 2.905e-16 79.0 COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - PSCyt1 CMS3_k127_352370_2 1121007.AUML01000006_gene3132 2.263e-160 512.0 COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,1HZA0@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N CMS3_k127_352370_6 880072.Desac_2439 2.851e-116 380.0 COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2WXBI@28221|Deltaproteobacteria 28221|Deltaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 CMS3_k127_352370_0 760192.Halhy_0777 4.707e-186 601.0 COG1226@1|root,COG1226@2|Bacteria,4NMQN@976|Bacteroidetes 976|Bacteroidetes P secreted protein - - - - - - - - - - - - Castor_Poll_mid CMS3_k127_352370_8 1492737.FEM08_24610 5.227e-83 284.0 COG0745@1|root,COG0745@2|Bacteria,4NHXA@976|Bacteroidetes,1HZWH@117743|Flavobacteriia,2NSGF@237|Flavobacterium 976|Bacteroidetes T Transcriptional regulator - - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_352370_1 1492737.FEM08_24620 2.06e-166 536.0 COG0642@1|root,COG2205@2|Bacteria,4NGAS@976|Bacteroidetes,1I0EI@117743|Flavobacteriia,2NYNR@237|Flavobacterium 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA,TPR_8 CMS3_k127_352370_7 406552.NJ7G_2116 5.273e-98 329.0 COG1653@1|root,arCOG00151@2157|Archaea,2Y2AY@28890|Euryarchaeota,23Z4Y@183963|Halobacteria 183963|Halobacteria G COG1653 ABC-type sugar transport system, periplasmic component - - - - - - - - - - - - - CMS3_k127_352370_11 1120968.AUBX01000017_gene2022 1.168e-52 192.0 COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,47QA2@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_352370_5 929556.Solca_0266 4.33e-119 415.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_352370_16 760192.Halhy_2187 5.811e-19 90.0 COG1695@1|root,COG1695@2|Bacteria,4PK5I@976|Bacteroidetes,1IZJS@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Transcriptional regulator PadR N-terminal-like - - - - - - - - - - - - PadR CMS3_k127_352370_3 1185876.BN8_01430 4.789e-128 438.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_352370_10 925409.KI911562_gene2727 7.476e-54 195.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding - - - - - - - - - - - - cNMP_binding CMS3_k127_352370_13 1380386.JIAW01000007_gene3770 9.323e-45 174.0 COG0702@1|root,COG0702@2|Bacteria,2HC75@201174|Actinobacteria,23EBG@1762|Mycobacteriaceae 201174|Actinobacteria GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 CMS3_k127_352370_4 1121875.KB907548_gene1528 1.926e-126 421.0 COG2355@1|root,COG2355@2|Bacteria,4NI3V@976|Bacteroidetes,1I0XS@117743|Flavobacteriia 976|Bacteroidetes E Zn-dependent dipeptidase, microsomal dipeptidase - - - - - - - - - - - - Peptidase_M19 CMS3_k127_352370_9 388413.ALPR1_12825 7.049e-61 223.0 COG4782@1|root,COG4782@2|Bacteria,4NZDN@976|Bacteroidetes 976|Bacteroidetes S Alpha/beta hydrolase of unknown function (DUF900) - - - - - - - - - - - - DUF900 CMS3_k127_352370_14 1123248.KB893324_gene1763 1.36e-44 169.0 COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia 976|Bacteroidetes K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg CMS3_k127_352370_12 1237149.C900_05518 7.028e-46 176.0 COG4585@1|root,COG4585@2|Bacteria,4NN4R@976|Bacteroidetes,47N81@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 CMS3_k127_352370_15 485918.Cpin_5476 1.835e-44 170.0 COG2197@1|root,COG2197@2|Bacteria,4NKAD@976|Bacteroidetes,1IT3A@117747|Sphingobacteriia 976|Bacteroidetes K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg CMS3_k127_352370_17 1046714.AMRX01000008_gene1120 2.296e-12 74.0 COG2819@1|root,COG2819@2|Bacteria,1PTJI@1224|Proteobacteria,1T1D3@1236|Gammaproteobacteria,464H2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Putative esterase - - - - - - - - - - - - Esterase CMS3_k127_352370_19 471854.Dfer_0536 1.062e-07 55.0 COG0642@1|root,COG0745@1|root,COG2207@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_358777_0 1123277.KB893175_gene1404 2.667e-53 190.0 COG0454@1|root,COG0454@2|Bacteria,4NPMJ@976|Bacteroidetes,47Q7Y@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_358777_1 1250232.JQNJ01000001_gene1256 4.435e-31 124.0 2ESJ3@1|root,33K3T@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - ABM CMS3_k127_358777_2 886293.Sinac_3002 1.101e-25 120.0 29VFX@1|root,30GX8@2|Bacteria,2IZ6B@203682|Planctomycetes 203682|Planctomycetes S Glycosyltransferase family 87 - - - - - - - - - - - - GT87 CMS3_k127_3628025_5 984262.SGRA_1302 8.72e-05 51.0 2E0MA@1|root,32W6I@2|Bacteria,4NNWD@976|Bacteroidetes 976|Bacteroidetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_3628025_3 203124.Tery_4625 3.424e-16 94.0 COG1672@1|root,COG2319@1|root,COG4249@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,COG4249@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales 1117|Cyanobacteria KLT WD domain, G-beta repeat - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Peptidase_C14,TIR_2,TPR_8,WD40 CMS3_k127_3628025_0 880071.Fleli_3743 5.212e-69 265.0 COG1672@1|root,COG1672@2|Bacteria,4NR06@976|Bacteroidetes,47QBP@768503|Cytophagia 976|Bacteroidetes S PFAM Archaeal ATPase - - - - - - - - - - - - AAA_16 CMS3_k127_3628025_1 1121875.KB907549_gene1707 1.886e-61 236.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_3628025_2 1121904.ARBP01000045_gene1842 1.889e-19 104.0 COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47TVA@768503|Cytophagia 976|Bacteroidetes T helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,TPR_12,TPR_8,Y_Y_Y CMS3_k127_3653965_7 1123057.P872_08345 1.037e-12 70.0 COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia 976|Bacteroidetes L pfam nudix - - - - - - - - - - - - NUDIX CMS3_k127_3653965_2 1288963.ADIS_3136 3.882e-82 276.0 COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,47Q0N@768503|Cytophagia 976|Bacteroidetes P Iron-storage protein ftnA - 1.16.3.2 ko:K02217 - - - - ko00000,ko01000 - - - Ferritin CMS3_k127_3653965_6 1279009.ADICEAN_00831 2.96e-18 94.0 COG3527@1|root,COG3527@2|Bacteria,4NKWJ@976|Bacteroidetes 976|Bacteroidetes Q Alpha-acetolactate decarboxylase - - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy CMS3_k127_3653965_0 1237149.C900_03056 0.0 1313.0 COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia 976|Bacteroidetes C aconitate hydratase acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C CMS3_k127_3653965_3 926549.KI421517_gene1420 1.013e-77 271.0 COG1012@1|root,COG1012@2|Bacteria,4NEEZ@976|Bacteroidetes,47K6Q@768503|Cytophagia 976|Bacteroidetes C PFAM Acyl-CoA reductase (LuxC) - - - - - - - - - - - - LuxC CMS3_k127_3653965_4 1218108.KB908292_gene1372 5.923e-53 188.0 COG1145@1|root,COG1145@2|Bacteria,4NNF9@976|Bacteroidetes,1I1ZJ@117743|Flavobacteriia 976|Bacteroidetes C Ferredoxin fdx - - - - - - - - - - - Fer4,Fer4_7 CMS3_k127_3653965_1 1237149.C900_05083 2.697e-148 473.0 COG1721@1|root,COG1721@2|Bacteria,4NG0C@976|Bacteroidetes,47JTH@768503|Cytophagia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 CMS3_k127_3653965_5 1237149.C900_05084 1.215e-50 182.0 2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,47R7K@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3276) - - - - - - - - - - - - DUF3276 CMS3_k127_3653965_8 313606.M23134_01951 5.384e-10 63.0 COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47KKW@768503|Cytophagia 976|Bacteroidetes S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport CMS3_k127_3670215_1 929556.Solca_4267 7.604e-65 230.0 COG0566@1|root,COG0566@2|Bacteria,4NEFJ@976|Bacteroidetes,1IXJ7@117747|Sphingobacteriia 976|Bacteroidetes J PFAM SpoU rRNA Methylase family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind CMS3_k127_3670215_0 760192.Halhy_3393 4.977e-109 359.0 COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,1IRFX@117747|Sphingobacteriia 976|Bacteroidetes J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM CMS3_k127_3670215_2 641524.ADICYQ_0964 1.014e-21 100.0 COG1765@1|root,COG1765@2|Bacteria,4NNTY@976|Bacteroidetes,47R4T@768503|Cytophagia 976|Bacteroidetes O OsmC-like protein - - - ko:K07397 - - - - ko00000 - - - OsmC CMS3_k127_3670215_3 313603.FB2170_10289 8.729e-05 50.0 COG2114@1|root,COG2114@2|Bacteria,4NF1F@976|Bacteroidetes,1HZ1W@117743|Flavobacteriia,2PHTE@252356|Maribacter 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg CMS3_k127_3692944_1 1237149.C900_05293 4.625e-87 298.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3692944_2 136037.KDR17756 1.768e-76 266.0 COG0329@1|root,2QWNS@2759|Eukaryota,399HY@33154|Opisthokonta,3BGNT@33208|Metazoa,3CUM9@33213|Bilateria,41YKH@6656|Arthropoda,3SQJY@50557|Insecta 33208|Metazoa E Dihydrodipicolinate synthetase family HOGA1 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.3.16 ko:K18123 ko00330,ko00630,ko01100,map00330,map00630,map01100 - R00470,R00471 RC00307,RC00308 ko00000,ko00001,ko01000 - - - DHDPS CMS3_k127_3692944_0 641526.ADIWIN_3096 8.466e-164 523.0 COG0075@1|root,COG0075@2|Bacteria,4NH61@976|Bacteroidetes,1HY2N@117743|Flavobacteriia 976|Bacteroidetes E Aminotransferase class-V phnW - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K03430 ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R04152 RC00006,RC00008,RC00018,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CMS3_k127_3692944_3 945713.IALB_3148 6.046e-70 252.0 2CESB@1|root,2Z8UZ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF481 CMS3_k127_3692944_5 1237149.C900_04329 4.79e-30 136.0 COG3386@1|root,COG3386@2|Bacteria,4PKKP@976|Bacteroidetes 976|Bacteroidetes G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - SGL CMS3_k127_3692944_4 1242864.D187_007077 8.74e-41 156.0 2E3VP@1|root,32YSV@2|Bacteria,1RFZF@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS3_k127_3697030_12 269798.CHU_3239 1.627e-100 341.0 COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47JF1@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_3697030_6 1237149.C900_01814 3.641e-156 502.0 COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,47KQT@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein porV - - - - - - - - - - - - CMS3_k127_3697030_3 1237149.C900_01813 3.377e-301 961.0 COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia 976|Bacteroidetes S Peptidase family C25 porU - - - - - - - - - - - Peptidase_C25 CMS3_k127_3697030_21 761193.Runsl_3788 1.14e-52 193.0 COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,47PCF@768503|Cytophagia 976|Bacteroidetes I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf CMS3_k127_3697030_17 153721.MYP_4849 9.36e-77 264.0 COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia 976|Bacteroidetes P PFAM Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_3697030_18 1121481.AUAS01000012_gene314 9.282e-76 266.0 COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia 976|Bacteroidetes E PFAM FAD dependent oxidoreductase thiO - - - - - - - - - - - DAO CMS3_k127_3697030_1 1237149.C900_01809 0.0 1138.0 COG0823@1|root,COG0823@2|Bacteria,4PNV1@976|Bacteroidetes,47YIP@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - PD40 CMS3_k127_3697030_15 1237149.C900_01808 4.687e-94 317.0 COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,47JXA@768503|Cytophagia 976|Bacteroidetes S PFAM YicC-like family, N-terminal region - - - - - - - - - - - - DUF1732,YicC_N CMS3_k127_3697030_14 1237149.C900_04701 2.159e-95 316.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_3697030_25 523791.Kkor_1037 6.161e-07 56.0 COG5652@1|root,COG5652@2|Bacteria 2|Bacteria - - fjo27 - - - - - - - - - - - VanZ CMS3_k127_3697030_20 1288963.ADIS_0945 2.05e-57 202.0 COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,47QD7@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H CMS3_k127_3697030_0 1237149.C900_04704 0.0 2685.0 COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,47K4H@768503|Cytophagia 976|Bacteroidetes D Motility related/secretion protein sprA - - - - - - - - - - - SprA_N CMS3_k127_3697030_19 1237149.C900_04705 1.064e-69 241.0 COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,47N8D@768503|Cytophagia 976|Bacteroidetes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N CMS3_k127_3697030_2 1237149.C900_04706 0.0 1092.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,47JSR@768503|Cytophagia 976|Bacteroidetes C Phosphate acetyl butaryl transferase maeB - 1.1.1.38,1.1.1.40 ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 M00169,M00172 R00214,R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic CMS3_k127_3697030_13 1237149.C900_04707 8.372e-100 336.0 COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,47NDQ@768503|Cytophagia 976|Bacteroidetes L Domain of unknown function (DUF4837) - - - - - - - - - - - - DUF4837 CMS3_k127_3697030_5 1237149.C900_04708 1.801e-162 526.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,47KJK@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS3_k127_3697030_24 643867.Ftrac_3331 4.666e-21 94.0 COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,47S09@768503|Cytophagia 976|Bacteroidetes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 CMS3_k127_3697030_11 643867.Ftrac_3330 5.387e-103 348.0 COG4942@1|root,COG4942@2|Bacteria,4NH2T@976|Bacteroidetes,47JWJ@768503|Cytophagia 976|Bacteroidetes D Peptidase, M23 envC - - - - - - - - - - - Peptidase_M23 CMS3_k127_3697030_22 1279009.ADICEAN_00297 1.773e-31 133.0 COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia 976|Bacteroidetes M Domain of unknown function (DUF4292) - - - - - - - - - - - - DUF4292 CMS3_k127_3697030_7 1237149.C900_04713 4.425e-142 470.0 COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,47KE1@768503|Cytophagia 976|Bacteroidetes S PFAM Tetratricopeptide - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 CMS3_k127_3697030_8 1237149.C900_04715 1.113e-139 459.0 COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,47MQE@768503|Cytophagia 976|Bacteroidetes S Polysaccharide biosynthesis protein cap - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C CMS3_k127_3697030_16 1237149.C900_04716 2.908e-91 306.0 COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family crt - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 CMS3_k127_3697030_9 1120965.AUBV01000001_gene3484 4.815e-133 431.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,47JUZ@768503|Cytophagia 976|Bacteroidetes M PFAM NAD dependent epimerase dehydratase family ltd - - - - - - - - - - - Epimerase CMS3_k127_3697030_4 1313301.AUGC01000008_gene386 1.081e-208 653.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_3697030_10 1237149.C900_04724 2.094e-110 364.0 COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,47JT6@768503|Cytophagia 976|Bacteroidetes S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - - - - - - - - - - - DisA_N CMS3_k127_3698073_14 309807.SRU_1454 6.261e-11 76.0 COG2374@1|root,COG2374@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Endonuclease_1,Exo_endo_phos,LTD CMS3_k127_3698073_6 1487953.JMKF01000006_gene5751 1.387e-57 228.0 COG2304@1|root,COG2931@1|root,COG4932@1|root,COG5276@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1G1I0@1117|Cyanobacteria,1H84J@1150|Oscillatoriales 1117|Cyanobacteria Q RTX toxins and related Ca2 binding proteins - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - Cadherin,Calx-beta,DUF4347,HemolysinCabind,Lectin_C CMS3_k127_3698073_1 926556.Echvi_2430 1.716e-244 759.0 COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,47KGI@768503|Cytophagia 976|Bacteroidetes H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD CMS3_k127_3698073_5 929703.KE386491_gene292 4.583e-58 211.0 COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia 976|Bacteroidetes H PFAM Biotin lipoate A B protein ligase birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_LplA_LipB CMS3_k127_3698073_9 1189612.A33Q_3170 1.378e-43 161.0 COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia 976|Bacteroidetes S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS CMS3_k127_3698073_0 1237149.C900_05721 0.0 1068.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia 976|Bacteroidetes O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CMS3_k127_3698073_4 1237149.C900_05722 2.25e-93 313.0 COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,47JQJ@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 CMS3_k127_3698073_8 1121904.ARBP01000005_gene4760 4.194e-48 181.0 COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia 976|Bacteroidetes KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg CMS3_k127_3698073_2 1237149.C900_05728 6.381e-234 730.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_3698073_3 1120966.AUBU01000002_gene2107 2.591e-118 395.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c CMS3_k127_3698073_12 1237149.C900_05730 2.224e-28 116.0 COG0236@1|root,COG0236@2|Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_3698073_7 269798.CHU_3634 2.191e-50 186.0 2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3698073_13 1122611.KB903952_gene5913 6.663e-12 72.0 COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4EIQ8@85012|Streptosporangiales 201174|Actinobacteria S YceI-like domain - - - - - - - - - - - - YceI CMS3_k127_3698073_15 1499967.BAYZ01000095_gene4264 1.523e-08 64.0 COG1073@1|root,COG1073@2|Bacteria,2NRK4@2323|unclassified Bacteria 2|Bacteria S Alpha/beta hydrolase of unknown function (DUF1100) CP_0620 - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,DLH,Hydrolase_4,Peptidase_S9 CMS3_k127_3743709_3 1237149.C900_05600 8.05e-16 80.0 2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,47QS1@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 CMS3_k127_3743709_2 1124780.ANNU01000021_gene3033 7.915e-21 98.0 2EVP8@1|root,334YW@2|Bacteria,4NX4R@976|Bacteroidetes,47SHG@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 CMS3_k127_3743709_0 1237149.C900_05598 2.493e-159 512.0 COG0044@1|root,COG0044@2|Bacteria,4NDUZ@976|Bacteroidetes,47KKP@768503|Cytophagia 976|Bacteroidetes F TIGRFAM dihydroorotase, multifunctional complex type pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 CMS3_k127_3743709_1 1237149.C900_05597 5.996e-121 403.0 COG1361@1|root,COG1361@2|Bacteria,4PKPA@976|Bacteroidetes 976|Bacteroidetes M Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,CARDB CMS3_k127_3777498_3 118168.MC7420_2969 3.834e-07 64.0 COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7TA@1150|Oscillatoriales 1117|Cyanobacteria M Wd40 repeat-containing protein - - - - - - - - - - - - AAA_16,WD40 CMS3_k127_3777498_1 945713.IALB_0968 5.003e-61 238.0 COG4249@1|root,COG4249@2|Bacteria 2|Bacteria S B-1 B cell differentiation - - - - - - - - - - - - Peptidase_C14,Sel1,TPR_8,WG_beta_rep CMS3_k127_3777498_0 1121875.KB907548_gene1646 7.673e-75 265.0 COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZK0@117743|Flavobacteriia 976|Bacteroidetes K AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_3777498_2 880073.Calab_1674 8.896e-09 66.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CMS3_k127_3786403_6 643867.Ftrac_1730 1.02e-109 372.0 COG3292@1|root,COG4251@1|root,COG3292@2|Bacteria,COG4251@2|Bacteria,4NKGA@976|Bacteroidetes 976|Bacteroidetes KT Two component regulator propeller - - - - - - - - - - - - HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y CMS3_k127_3786403_5 1237149.C900_04036 5.169e-122 408.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,PAS_8 CMS3_k127_3786403_3 1237149.C900_04037 9.245e-191 604.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_3786403_0 1237149.C900_04040 1.176e-251 799.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3786403_4 1237149.C900_04040 2.678e-163 541.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3786403_2 1237149.C900_04044 1.408e-204 662.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3786403_1 1237149.C900_03827 1.452e-242 772.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3786403_8 1237149.C900_04045 2.813e-59 217.0 COG3595@1|root,COG3595@2|Bacteria,4NMHT@976|Bacteroidetes,47PEC@768503|Cytophagia 976|Bacteroidetes S Putative adhesin - - - - - - - - - - - - DUF4097 CMS3_k127_3786403_7 1237149.C900_04413 1.54e-102 341.0 COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,47K5F@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 CMS3_k127_3803855_0 269798.CHU_2090 2.966e-49 185.0 COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia 976|Bacteroidetes S DUF218 domain - - - - - - - - - - - - DUF218 CMS3_k127_3803855_3 1173028.ANKO01000050_gene1108 0.0001326 51.0 COG0515@1|root,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria 1117|Cyanobacteria KLT PFAM Protein kinase domain - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase,Ppx-GppA,RDD CMS3_k127_3803855_1 929704.Myrod_3068 2.466e-26 114.0 2DD3M@1|root,2ZGBQ@2|Bacteria,4P80Y@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3803855_2 517722.AEUE01000006_gene1854 2.9e-06 56.0 29CEM@1|root,2ZZD2@2|Bacteria,1RB3W@1224|Proteobacteria,2U9X1@28211|Alphaproteobacteria,2K4Y7@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - CMS3_k127_3820452_1 1124780.ANNU01000019_gene1740 5.822e-250 804.0 COG4447@1|root,COG4447@2|Bacteria,4NI13@976|Bacteroidetes,47NV6@768503|Cytophagia 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_3820452_8 1124780.ANNU01000019_gene1745 2.941e-67 231.0 COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,47PVC@768503|Cytophagia 976|Bacteroidetes H TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS CMS3_k127_3820452_5 1124780.ANNU01000019_gene1746 3.085e-121 399.0 COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,47JDC@768503|Cytophagia 976|Bacteroidetes M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB CMS3_k127_3820452_2 866536.Belba_1932 3.214e-194 612.0 COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,47JDR@768503|Cytophagia 976|Bacteroidetes O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX CMS3_k127_3820452_6 1237149.C900_00195 3.886e-102 337.0 COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,47K60@768503|Cytophagia 976|Bacteroidetes OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease CMS3_k127_3820452_4 1237149.C900_00194 4.564e-142 465.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,47KTD@768503|Cytophagia 976|Bacteroidetes O Trigger factor tig - - ko:K03545 - - - - ko00000 - - - Trigger_C,Trigger_N CMS3_k127_3820452_0 1237149.C900_00193 0.0 1113.0 COG0317@1|root,COG0317@2|Bacteria,4NESY@976|Bacteroidetes,47JQ8@768503|Cytophagia 976|Bacteroidetes KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS CMS3_k127_3820452_7 153721.MYP_4639 6.328e-75 254.0 COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,47P99@768503|Cytophagia 976|Bacteroidetes P Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR CMS3_k127_3820452_9 1237149.C900_00191 9.05e-44 161.0 COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes,47R73@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS CMS3_k127_3820452_3 1237149.C900_00190 5.968e-194 612.0 COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,47JQ0@768503|Cytophagia 976|Bacteroidetes F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt CMS3_k127_3836780_13 7739.XP_002598600.1 8.637e-21 103.0 COG5279@1|root,KOG4575@2759|Eukaryota,39WFT@33154|Opisthokonta,3BIKZ@33208|Metazoa,3D1NX@33213|Bilateria,480EJ@7711|Chordata 33208|Metazoa D Kyphoscoliosis peptidase KY GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0007275,GO:0007517,GO:0007528,GO:0008150,GO:0009987,GO:0016043,GO:0030016,GO:0030017,GO:0030018,GO:0031674,GO:0032501,GO:0032502,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0048513,GO:0048731,GO:0048856,GO:0050808,GO:0061061,GO:0071840,GO:0099080,GO:0099081,GO:0099512 - - - - - - - - - - Transglut_core CMS3_k127_3836780_1 1237149.C900_04526 1.917e-259 807.0 COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,47KC6@768503|Cytophagia 976|Bacteroidetes J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 CMS3_k127_3836780_15 761193.Runsl_4607 2.114e-07 52.0 2EIUI@1|root,33CJV@2|Bacteria,4NYR6@976|Bacteroidetes,47T08@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3836780_9 1237149.C900_04527 2.168e-66 235.0 COG4235@1|root,COG4235@2|Bacteria,4PMDP@976|Bacteroidetes,47Y29@768503|Cytophagia 976|Bacteroidetes O Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 CMS3_k127_3836780_12 1121373.KB903620_gene2207 1.15e-45 166.0 COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,47QBN@768503|Cytophagia 976|Bacteroidetes L Belongs to the bacterial histone-like protein family hupA - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding CMS3_k127_3836780_5 643867.Ftrac_2591 4.196e-94 319.0 COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,47KTH@768503|Cytophagia 976|Bacteroidetes L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 CMS3_k127_3836780_10 1121904.ARBP01000015_gene247 2.667e-53 190.0 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia 976|Bacteroidetes L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB CMS3_k127_3836780_3 1237149.C900_04531 1.222e-177 567.0 COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,47JUX@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated protein GldE gldE - - - - - - - - - - - CBS,CorC_HlyC,DUF21 CMS3_k127_3836780_7 1279009.ADICEAN_04115 2.395e-84 284.0 293VW@1|root,2ZRB2@2|Bacteria,4NMK7@976|Bacteroidetes,47PUM@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated lipoprotein GldD gldD - - - - - - - - - - - - CMS3_k127_3836780_0 1237149.C900_04535 0.0 1031.0 COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,47JUE@768503|Cytophagia 976|Bacteroidetes L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge CMS3_k127_3836780_4 1237149.C900_01522 6.299e-161 539.0 COG3292@1|root,COG3292@2|Bacteria,4NNTX@976|Bacteroidetes,47U09@768503|Cytophagia 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - Y_Y_Y CMS3_k127_3836780_6 1237149.C900_01523 4.859e-87 296.0 28IIU@1|root,2Z8JV@2|Bacteria,4NEFH@976|Bacteroidetes,47JU3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3836780_14 1408473.JHXO01000011_gene3012 7.474e-10 66.0 2ET9N@1|root,33KTN@2|Bacteria,4NZKP@976|Bacteroidetes,2FZMH@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3836780_8 153721.MYP_3095 4.003e-81 275.0 COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia 976|Bacteroidetes O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR CMS3_k127_3836780_2 388413.ALPR1_18233 2.678e-213 674.0 COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47M14@768503|Cytophagia 976|Bacteroidetes G Peptidase, M28 PGCP - - - - - - - - - - - Peptidase_M28 CMS3_k127_3836780_11 391598.FBBAL38_00070 2.134e-48 185.0 COG2378@1|root,COG2378@2|Bacteria,4NN6R@976|Bacteroidetes,1IAE5@117743|Flavobacteriia 976|Bacteroidetes K WYL domain - - - - - - - - - - - - HTH_11,WYL CMS3_k127_3845119_21 1121904.ARBP01000001_gene5825 1.322e-06 53.0 2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47JNN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Caps_assemb_Wzi CMS3_k127_3845119_18 1237149.C900_03962 2.244e-41 153.0 COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,47R60@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 CMS3_k127_3845119_10 1408473.JHXO01000004_gene20 6.782e-102 338.0 COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,2G3EE@200643|Bacteroidia 976|Bacteroidetes M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix CMS3_k127_3845119_15 1408433.JHXV01000006_gene2768 5.578e-64 230.0 COG3137@1|root,COG3137@2|Bacteria,4NGB2@976|Bacteroidetes,1HY5S@117743|Flavobacteriia,2PAT9@246874|Cryomorphaceae 976|Bacteroidetes M Protein of unknown function (DUF3078) - - - - - - - - - - - - DUF3078 CMS3_k127_3845119_5 926549.KI421517_gene161 2.045e-147 476.0 COG1207@1|root,COG1207@2|Bacteria,4NDZP@976|Bacteroidetes,47XWC@768503|Cytophagia 976|Bacteroidetes M Sugar nucleotidyl transferase glmU - - - - - - - - - - - NTP_transf_4 CMS3_k127_3845119_0 643867.Ftrac_0005 2.886e-197 619.0 COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,47JCV@768503|Cytophagia 976|Bacteroidetes Q Homogentisate 12-dioxygenase - - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA CMS3_k127_3845119_3 1048983.EL17_14375 4.303e-182 585.0 COG0793@1|root,COG0793@2|Bacteria,4NEGV@976|Bacteroidetes,47JP7@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family ctp - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 CMS3_k127_3845119_13 1237149.C900_01741 2.415e-84 286.0 COG2846@1|root,COG2846@2|Bacteria,4NPQ7@976|Bacteroidetes,47PY2@768503|Cytophagia 976|Bacteroidetes D Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - ko:K07322 - - - - ko00000 - - - Hemerythrin CMS3_k127_3845119_19 1121481.AUAS01000003_gene3868 6.986e-39 149.0 COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,47QCM@768503|Cytophagia 976|Bacteroidetes L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX CMS3_k127_3845119_14 1124780.ANNU01000069_gene1075 2.122e-78 266.0 COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,47JIG@768503|Cytophagia 976|Bacteroidetes J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase CMS3_k127_3845119_7 1124780.ANNU01000043_gene330 6.564e-139 451.0 COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,47MBR@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_3845119_12 1189612.A33Q_3807 1.098e-86 294.0 COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,47JPF@768503|Cytophagia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yafV - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase CMS3_k127_3845119_6 1237149.C900_01734 1.39e-145 473.0 COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,47MCP@768503|Cytophagia 976|Bacteroidetes M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS3_k127_3845119_8 1453500.AT05_01360 7.388e-131 426.0 COG0338@1|root,COG0338@2|Bacteria,4NFZ2@976|Bacteroidetes,1I484@117743|Flavobacteriia 976|Bacteroidetes L DNA adenine methylase dam - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 CMS3_k127_3845119_16 926562.Oweho_1534 1.212e-44 174.0 COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,1HXZM@117743|Flavobacteriia 976|Bacteroidetes K AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_3845119_11 1237149.C900_05483 1.145e-91 311.0 COG2138@1|root,COG2138@2|Bacteria 2|Bacteria S sirohydrochlorin cobaltochelatase activity cbiX - 4.99.1.3 ko:K03795 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05807 RC01012 ko00000,ko00001,ko01000 - - - CbiX CMS3_k127_3845119_4 886377.Murru_0617 4.196e-178 567.0 COG0624@1|root,COG0624@2|Bacteria,4NI66@976|Bacteroidetes,1HZ8W@117743|Flavobacteriia 976|Bacteroidetes E Peptidase dimerisation domain - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 CMS3_k127_3845119_2 313606.M23134_00734 1.695e-187 634.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia 2|Bacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8 CMS3_k127_3845119_1 643867.Ftrac_1017 1.414e-191 619.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes,47K81@768503|Cytophagia 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_3845119_17 1313301.AUGC01000005_gene214 4.691e-43 180.0 2EBR7@1|root,335R4@2|Bacteria,4P6KN@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3845119_9 1122621.ATZA01000021_gene1747 3.668e-130 444.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3845119_20 1237149.C900_04617 2.847e-20 94.0 COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia 976|Bacteroidetes M Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - HEAT,HEAT_2,Pro_isomerase CMS3_k127_3855112_1 1123057.P872_02235 1.249e-162 520.0 COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,47M7W@768503|Cytophagia 976|Bacteroidetes K Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - CMS3_k127_3855112_2 1121931.AUHG01000010_gene710 1.062e-134 435.0 COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,1I5ZB@117743|Flavobacteriia 976|Bacteroidetes S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS3_k127_3855112_3 1286632.P278_27310 4.863e-78 268.0 COG3485@1|root,COG3485@2|Bacteria,4NEZ1@976|Bacteroidetes,1I01Q@117743|Flavobacteriia 976|Bacteroidetes Q Dioxygenase - - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C CMS3_k127_3855112_0 1250278.JQNQ01000001_gene3177 5.575e-272 855.0 COG3934@1|root,COG3934@2|Bacteria,4NFVS@976|Bacteroidetes,1HZVW@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase CMS3_k127_3862754_1 1168289.AJKI01000065_gene3768 8.512e-67 237.0 COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,2FPU3@200643|Bacteroidia,3XIXH@558415|Marinilabiliaceae 976|Bacteroidetes M Bacterial lipid A biosynthesis acyltransferase waaM - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans CMS3_k127_3862754_0 1121875.KB907546_gene2610 3.67e-302 942.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_3862754_2 1124780.ANNU01000005_gene2511 3.053e-42 160.0 2CRSQ@1|root,32SPK@2|Bacteria,4NR94@976|Bacteroidetes,47RXT@768503|Cytophagia 976|Bacteroidetes S DoxX-like family - - - - - - - - - - - - DoxX_2 CMS3_k127_3890651_2 880073.Calab_3421 7.113e-177 563.0 COG0076@1|root,COG0076@2|Bacteria,2NQW3@2323|unclassified Bacteria 2|Bacteria E Pyridoxal-dependent decarboxylase conserved domain ddc - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC CMS3_k127_3890651_1 1249975.JQLP01000005_gene2202 0.0 1048.0 COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia,2P6KB@244698|Gillisia 976|Bacteroidetes P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3890651_0 760192.Halhy_5682 0.0 1055.0 COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,1IQBW@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_3890651_3 760192.Halhy_5681 1.659e-160 512.0 COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,1IRIC@117747|Sphingobacteriia 976|Bacteroidetes G COGs COG2152 glycosylase - - 2.4.1.339,2.4.1.340 ko:K20885 - - R11397,R11398 RC00049,RC02748 ko00000,ko01000 - GH130 - Glyco_hydro_130 CMS3_k127_3890651_5 760192.Halhy_5643 9.947e-11 63.0 2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,1IUQI@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - TspO_MBR CMS3_k127_3890651_4 755732.Fluta_3077 1.663e-48 180.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 CMS3_k127_3901591_19 1237149.C900_02200 5.848e-39 148.0 COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47S5T@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 CMS3_k127_3901591_20 649349.Lbys_2850 5.052e-28 117.0 COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,47RJW@768503|Cytophagia 976|Bacteroidetes S small membrane protein - - - - - - - - - - - - DUF423 CMS3_k127_3901591_13 1237149.C900_02196 6.868e-76 260.0 COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes,47M4Y@768503|Cytophagia 976|Bacteroidetes S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis yggS - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N CMS3_k127_3901591_3 1305737.JAFX01000001_gene383 7.801e-234 732.0 COG0318@1|root,COG0318@2|Bacteria,4PKQG@976|Bacteroidetes,47K42@768503|Cytophagia 976|Bacteroidetes IQ GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 CMS3_k127_3901591_16 1237149.C900_02194 6.108e-43 164.0 COG1280@1|root,COG1280@2|Bacteria,4NH3F@976|Bacteroidetes,47NRD@768503|Cytophagia 976|Bacteroidetes E PFAM Lysine exporter protein (LYSE YGGA) - - - - - - - - - - - - LysE CMS3_k127_3901591_7 1237149.C900_02193 6.764e-161 512.0 COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia 976|Bacteroidetes S PFAM von Willebrand factor type A batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA CMS3_k127_3901591_14 1124780.ANNU01000024_gene3091 1.993e-59 216.0 2BPYJ@1|root,32ISF@2|Bacteria,4NRVJ@976|Bacteroidetes,47QN3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3901591_11 1237149.C900_02191 8.208e-134 435.0 COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,47JXB@768503|Cytophagia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 CMS3_k127_3901591_21 866536.Belba_3723 1.913e-20 95.0 2EK3P@1|root,33DU3@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4296) - - - - - - - - - - - - DUF4296 CMS3_k127_3901591_6 1166018.FAES_1440 1.156e-176 580.0 COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,47KJ6@768503|Cytophagia 976|Bacteroidetes L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr CMS3_k127_3901591_15 1237149.C900_02186 3.966e-55 199.0 COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,47PDC@768503|Cytophagia 976|Bacteroidetes V PFAM ABC transporter - - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran CMS3_k127_3901591_10 1237149.C900_02185 2.383e-140 449.0 COG1043@1|root,COG1043@2|Bacteria,4NEBA@976|Bacteroidetes,47JJC@768503|Cytophagia 976|Bacteroidetes M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep CMS3_k127_3901591_2 1237149.C900_02184 1.818e-259 804.0 COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,4NEJ3@976|Bacteroidetes,47JFB@768503|Cytophagia 976|Bacteroidetes IM Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis fabZ - 3.5.1.108,4.2.1.59 ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 M00060,M00083 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 - - - FabA,LpxC CMS3_k127_3901591_8 1237149.C900_02183 2.048e-144 465.0 COG1044@1|root,COG1044@2|Bacteria,4NE5G@976|Bacteroidetes,47J9Z@768503|Cytophagia 976|Bacteroidetes M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD CMS3_k127_3901591_9 643867.Ftrac_3535 1.55e-142 463.0 COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,47JI5@768503|Cytophagia 976|Bacteroidetes S SMART Metal-dependent phosphohydrolase, HD region - - - ko:K06885 - - - - ko00000 - - - HD CMS3_k127_3901591_1 1237149.C900_02181 1.083e-265 825.0 COG2204@1|root,COG2204@2|Bacteria,4NE72@976|Bacteroidetes,47KVF@768503|Cytophagia 976|Bacteroidetes T CheY-like receiver AAA-type ATPase and DNA-binding domains porX - - - - - - - - - - - PglZ,Response_reg CMS3_k127_3901591_18 1150600.ADIARSV_2414 2.806e-40 153.0 COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ISTA@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Uncharacterised protein family UPF0079, ATPase yjeE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE CMS3_k127_3901591_5 1237149.C900_02179 8.756e-186 587.0 COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47J94@768503|Cytophagia 976|Bacteroidetes E PFAM Alanine dehydrogenase PNT, C-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N CMS3_k127_3901591_0 1124780.ANNU01000024_gene3108 0.0 1276.0 COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,47JHX@768503|Cytophagia 976|Bacteroidetes J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 CMS3_k127_3901591_4 1237149.C900_04904 2.953e-191 604.0 COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,47KTT@768503|Cytophagia 976|Bacteroidetes Q fumarylacetoacetate (FAA) hydrolase fahA - 3.7.1.2 ko:K01555 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FAA_hydrolase,FAA_hydrolase_N CMS3_k127_3901591_12 1189612.A33Q_2222 1.455e-116 383.0 COG1853@1|root,COG1853@2|Bacteria,4NF4H@976|Bacteroidetes,47KXZ@768503|Cytophagia 976|Bacteroidetes S PFAM Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct CMS3_k127_3901591_17 344747.PM8797T_16393 1.151e-40 153.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 CMS3_k127_3901591_22 1410613.JNKF01000018_gene2757 3.447e-15 89.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4P0NF@976|Bacteroidetes,2FRHA@200643|Bacteroidia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_3920052_0 1185876.BN8_00898 2.669e-90 312.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3920052_1 1535422.ND16A_1877 4.579e-65 248.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,2Q73E@267889|Colwelliaceae 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_16 CMS3_k127_3920052_3 1120966.AUBU01000002_gene2239 8.772e-45 182.0 COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47QEI@768503|Cytophagia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - Guanylate_cyc,HTH_18,TPR_16,TPR_8 CMS3_k127_3920052_2 616991.JPOO01000001_gene3046 2.507e-49 188.0 COG1560@1|root,COG1560@2|Bacteria,4NGQU@976|Bacteroidetes,1HYHF@117743|Flavobacteriia,23FX7@178469|Arenibacter 976|Bacteroidetes M Bacterial lipid A biosynthesis acyltransferase waaM - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans CMS3_k127_3920052_5 265729.GS18_0217905 2.817e-15 88.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 CMS3_k127_3920052_6 760192.Halhy_3114 4.342e-05 49.0 COG2114@1|root,COG4372@1|root,COG2114@2|Bacteria,COG4372@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia 976|Bacteroidetes T PFAM Adenylate and Guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg,TPR_12 CMS3_k127_3920052_7 869213.JCM21142_31045 0.0002496 43.0 COG1418@1|root,COG2114@1|root,COG1418@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia 976|Bacteroidetes T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - 7TMR-DISM_7TM,Guanylate_cyc,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_3920052_4 313603.FB2170_08239 3.373e-32 128.0 COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2PH09@252356|Maribacter 976|Bacteroidetes E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - HEAT_2,Peptidase_M1 CMS3_k127_3938742_8 1237149.C900_01410 1.124e-07 53.0 COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,47R35@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, mercury resistance ycgE - - - - - - - - - - - MerR_1 CMS3_k127_3938742_3 1237149.C900_01411 1e-132 435.0 COG2843@1|root,COG2843@2|Bacteria,4NI6J@976|Bacteroidetes,47NKK@768503|Cytophagia 976|Bacteroidetes M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap CMS3_k127_3938742_6 1124780.ANNU01000032_gene1251 3.057e-85 293.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 CMS3_k127_3938742_2 1124780.ANNU01000032_gene1251 1.021e-145 467.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 CMS3_k127_3938742_0 1120966.AUBU01000010_gene2916 0.0 1146.0 COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,47KKH@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD CMS3_k127_3938742_7 1089547.KB913013_gene2967 2.947e-46 171.0 2B1RZ@1|root,31U7Q@2|Bacteria,4NR0B@976|Bacteroidetes,47Q5B@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3938742_5 1279009.ADICEAN_01474 4.102e-95 318.0 COG3186@1|root,COG3186@2|Bacteria,4NEX5@976|Bacteroidetes,47KWF@768503|Cytophagia 976|Bacteroidetes E PFAM Biopterin-dependent aromatic amino acid hydroxylase phhA - 1.14.16.1 ko:K00500 ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230 - R01795,R07211 RC00490 ko00000,ko00001,ko01000 - - - Biopterin_H CMS3_k127_3938742_1 1237149.C900_03312 3.358e-238 744.0 COG1249@1|root,COG1249@2|Bacteria,4NJ2P@976|Bacteroidetes,47NRN@768503|Cytophagia 976|Bacteroidetes C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim CMS3_k127_3938742_4 1237149.C900_03318 1.028e-99 330.0 COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia 976|Bacteroidetes C Nitroreductase family - - - - - - - - - - - - Nitroreductase CMS3_k127_4019394_0 1122176.KB903532_gene2674 0.0 1025.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,1IW0D@117747|Sphingobacteriia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4019394_3 760192.Halhy_4561 3.395e-131 438.0 COG0521@1|root,COG0521@2|Bacteria,4NFT1@976|Bacteroidetes,1IW8D@117747|Sphingobacteriia 976|Bacteroidetes H Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like,SusD-like_2 CMS3_k127_4019394_13 1122176.KB903532_gene2672 8.225e-05 54.0 2AM3F@1|root,31BXJ@2|Bacteria,4NPAN@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4019394_5 1121904.ARBP01000005_gene4641 1.712e-120 392.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS3_k127_4019394_12 483216.BACEGG_01890 2.919e-10 64.0 COG3630@1|root,COG3630@2|Bacteria,4NXVZ@976|Bacteroidetes,2FTVB@200643|Bacteroidia,4ARS0@815|Bacteroidaceae 976|Bacteroidetes C Sodium pump decarboxylase gamma subunit - - 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma CMS3_k127_4019394_1 1121904.ARBP01000007_gene2990 4.907e-278 866.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4NEQV@976|Bacteroidetes 976|Bacteroidetes C COG5016 Pyruvate oxaloacetate carboxyltransferase - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,Biotin_lipoyl_2,HMGL-like,PYC_OADA CMS3_k127_4019394_2 1121904.ARBP01000007_gene2989 3.827e-179 568.0 COG1883@1|root,COG1883@2|Bacteria,4NGCN@976|Bacteroidetes 976|Bacteroidetes C sodium ion-translocating decarboxylase, beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta CMS3_k127_4019394_11 1121285.AUFK01000003_gene302 2.654e-10 71.0 COG2207@1|root,COG2207@2|Bacteria,4NF63@976|Bacteroidetes,1HZAQ@117743|Flavobacteriia,3ZPMZ@59732|Chryseobacterium 976|Bacteroidetes K AraC family transcriptional regulator - - - - - - - - - - - - AraC_N,HTH_18,HTH_AraC CMS3_k127_4019394_10 926560.KE387023_gene2407 8.493e-33 133.0 COG1832@1|root,COG1832@2|Bacteria 2|Bacteria S CoA binding domain - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 CMS3_k127_4019394_8 880073.Calab_1912 2.297e-68 241.0 COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria 2|Bacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT CMS3_k127_4019394_6 118161.KB235922_gene3736 7.137e-113 378.0 COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,3VINB@52604|Pleurocapsales 1117|Cyanobacteria E Amino acid polyamine organocation transporter, APC superfamily - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CMS3_k127_4019394_4 929703.KE386491_gene1629 6.107e-124 424.0 COG1629@1|root,COG4771@2|Bacteria,4NET0@976|Bacteroidetes,47NCM@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10 - - CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec CMS3_k127_4019394_9 1506583.JQJY01000005_gene2268 4.054e-61 226.0 2CD2G@1|root,2Z833@2|Bacteria,4NHAR@976|Bacteroidetes,1HWSJ@117743|Flavobacteriia,2NSWZ@237|Flavobacterium 976|Bacteroidetes S HmuY protein - - - - - - - - - - - - HmuY CMS3_k127_4022176_14 1349785.BAUG01000032_gene1836 5.257e-45 173.0 COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia 976|Bacteroidetes O cytochrome c biogenesis ccsBA - - - - - - - - - - - Cytochrom_C_asm,ResB CMS3_k127_4022176_4 880073.Calab_1263 7.27e-152 497.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Paired_CXXCH_1 CMS3_k127_4022176_9 880073.Calab_1262 3.572e-75 264.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - NHL,TPR_11 CMS3_k127_4022176_7 880073.Calab_1271 4.207e-100 343.0 COG3005@1|root,COG3005@2|Bacteria,2NQ90@2323|unclassified Bacteria 2|Bacteria C Doubled CXXCH motif (Paired_CXXCH_1) - - - - - - - - - - - - Paired_CXXCH_1 CMS3_k127_4022176_8 880073.Calab_1270 1.856e-91 325.0 2ENA5@1|root,33FXV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4022176_15 443143.GM18_1016 1.931e-38 156.0 COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria 28221|Deltaproteobacteria C TIGRFAM cytochrome C family protein - - - - - - - - - - - - Paired_CXXCH_1 CMS3_k127_4022176_6 880073.Calab_1268 1.276e-113 380.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - NHL,TPR_11 CMS3_k127_4022176_11 880073.Calab_1267 4.689e-59 213.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - 1.7.2.2 ko:K03385 ko00910,ko01120,ko05132,map00910,map01120,map05132 M00530 R05712 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_C552,Paired_CXXCH_1 CMS3_k127_4022176_0 866536.Belba_0774 0.0 1245.0 COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,47JE2@768503|Cytophagia 976|Bacteroidetes L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CMS3_k127_4022176_10 1189612.A33Q_2577 4.799e-63 221.0 COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,47PEY@768503|Cytophagia 976|Bacteroidetes J PFAM SpoU rRNA Methylase family spoU - - - - - - - - - - - SpoU_methylase CMS3_k127_4022176_1 1237149.C900_04547 1.11e-244 762.0 COG0114@1|root,COG0114@2|Bacteria,4NEQP@976|Bacteroidetes,47JKQ@768503|Cytophagia 976|Bacteroidetes C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC - 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 CMS3_k127_4022176_12 1237149.C900_04546 1.134e-58 210.0 2DPU6@1|root,333E2@2|Bacteria,4NW9K@976|Bacteroidetes,47RVJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4022176_3 1124780.ANNU01000016_gene1814 1.418e-216 685.0 COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia 976|Bacteroidetes L single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS3_k127_4022176_5 1279009.ADICEAN_01942 5.537e-128 411.0 COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,47KI2@768503|Cytophagia 976|Bacteroidetes S ABC transporter lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C CMS3_k127_4022176_13 1237149.C900_00281 2.327e-56 217.0 COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes,47MD8@768503|Cytophagia 976|Bacteroidetes K Tetratricopeptide repeat - - - - - - - - - - - - TPR_12,TPR_8 CMS3_k127_4022176_2 1237149.C900_04542 2.514e-221 692.0 COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,47KAH@768503|Cytophagia 976|Bacteroidetes IQ PFAM GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 CMS3_k127_4042878_7 1237149.C900_03999 5.848e-16 82.0 COG0457@1|root,COG0457@2|Bacteria,4NGQ7@976|Bacteroidetes,47KHQ@768503|Cytophagia 976|Bacteroidetes U Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 CMS3_k127_4042878_4 1237149.C900_04001 1.477e-71 249.0 COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47JI7@768503|Cytophagia 976|Bacteroidetes I TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CMS3_k127_4042878_0 1121104.AQXH01000003_gene415 1.038e-196 621.0 COG0006@1|root,COG0006@2|Bacteria,4NF0F@976|Bacteroidetes,1IV0D@117747|Sphingobacteriia 976|Bacteroidetes E Metallopeptidase family M24 - - - - - - - - - - - - Peptidase_M24 CMS3_k127_4042878_3 1189612.A33Q_3092 6.178e-76 259.0 COG1607@1|root,COG1607@2|Bacteria,4NMK1@976|Bacteroidetes,47N9Z@768503|Cytophagia 976|Bacteroidetes I PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT CMS3_k127_4042878_1 1237149.C900_01857 7.536e-177 566.0 COG0534@1|root,COG0534@2|Bacteria,4NEBB@976|Bacteroidetes,47KYV@768503|Cytophagia 976|Bacteroidetes V efflux protein, MATE family norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE CMS3_k127_4042878_5 1120968.AUBX01000009_gene624 5.018e-71 244.0 COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia 976|Bacteroidetes L pfam nudix nudF - - - - - - - - - - - NUDIX CMS3_k127_4042878_2 999419.HMPREF1077_00234 6.739e-83 279.0 COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,22WJC@171551|Porphyromonadaceae 976|Bacteroidetes L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII CMS3_k127_4042878_6 1121324.CLIT_4c00250 2.016e-42 167.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,25RVB@186804|Peptostreptococcaceae 186801|Clostridia P CPA2 family - - - - - - - - - - - - Na_H_Exchanger CMS3_k127_40761_0 1237149.C900_05632 8.567e-159 531.0 COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia 976|Bacteroidetes S Peptidase family C25 - - - - - - - - - - - - CARDB,FlgD_ig,ILEI,Peptidase_C25 CMS3_k127_4090723_0 1121904.ARBP01000012_gene1252 3.05e-199 633.0 COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,47Y1Q@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4090723_6 557599.MKAN_03700 3.423e-64 229.0 COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,2369X@1762|Mycobacteriaceae 201174|Actinobacteria S short-chain dehydrogenase - - - ko:K07124 - - - - ko00000 - - - adh_short CMS3_k127_4090723_5 1415780.JPOG01000001_gene733 2.206e-68 243.0 COG3752@1|root,COG3752@2|Bacteria,1R4MV@1224|Proteobacteria,1S0DP@1236|Gammaproteobacteria,1X5SX@135614|Xanthomonadales 135614|Xanthomonadales S Protein of unknown function (DUF1295) - - - - - - - - - - - - DUF1295 CMS3_k127_4090723_7 13689.BV96_02007 4.642e-57 201.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4RU@204457|Sphingomonadales 204457|Sphingomonadales O Belongs to the MsrB Met sulfoxide reductase family msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR CMS3_k127_4090723_1 1124780.ANNU01000002_gene1614 3.259e-169 540.0 COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,47JS1@768503|Cytophagia 976|Bacteroidetes S PFAM FAD dependent oxidoreductase lhgO - - ko:K15736 - - - - ko00000,ko01000 - - - DAO CMS3_k127_4090723_2 1237149.C900_01348 1.807e-131 429.0 COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia 976|Bacteroidetes H MoeZ MoeB domain moeZ - 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF CMS3_k127_4090723_3 1048983.EL17_07850 8.69e-96 316.0 COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,47P9Q@768503|Cytophagia 976|Bacteroidetes F deoxynucleoside kinase dck - - - - - - - - - - - dNK CMS3_k127_4090723_4 1121904.ARBP01000011_gene1425 1.26e-85 293.0 COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47NZ9@768503|Cytophagia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - CMS3_k127_4090723_9 1237149.C900_01970 1.735e-45 170.0 COG2353@1|root,COG2353@2|Bacteria,4NSJH@976|Bacteroidetes,47QHY@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_4090723_10 1296415.JACC01000042_gene115 1.005e-15 82.0 COG2010@1|root,COG2010@2|Bacteria,4NWPQ@976|Bacteroidetes,1I6QB@117743|Flavobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - - CMS3_k127_4181141_12 1148.1208451 1.953e-12 73.0 COG2159@1|root,COG2159@2|Bacteria 2|Bacteria E amidohydrolase - - 4.1.1.46 ko:K07045,ko:K14333 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821 RC00390 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS3_k127_4181141_3 861299.J421_1475 5.61e-125 414.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 CMS3_k127_4181141_6 929556.Solca_0767 3.018e-43 165.0 COG2318@1|root,COG2318@2|Bacteria,4NUTN@976|Bacteroidetes,1IUDR@117747|Sphingobacteriia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_4181141_1 1122138.AQUZ01000004_gene888 5.545e-266 829.0 COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4DPTE@85009|Propionibacteriales 201174|Actinobacteria C PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein frdA GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 ko:K00239,ko:K00244,ko:K00278 ko00020,ko00190,ko00250,ko00620,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00250,map00620,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00115,M00149,M00150,M00173,M00374,M00376 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1552 FAD_binding_2,Succ_DH_flav_C CMS3_k127_4181141_5 1123024.AUII01000011_gene4421 1.334e-116 380.0 COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DZZS@85010|Pseudonocardiales 201174|Actinobacteria C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB - 1.3.5.1,1.3.5.4 ko:K00240,ko:K00245 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1553 Fer2_3,Fer4_10,Fer4_8 CMS3_k127_4181141_10 443218.AS9A_2958 4.403e-22 100.0 COG3029@1|root,COG3029@2|Bacteria,2IQ2Z@201174|Actinobacteria,23A9K@1762|Mycobacteriaceae 201174|Actinobacteria C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane frdC - - ko:K00246 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Fumarate_red_C CMS3_k127_4181141_9 1122138.AQUZ01000004_gene891 1.707e-24 106.0 COG3080@1|root,COG3080@2|Bacteria,2IMEN@201174|Actinobacteria 201174|Actinobacteria C Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane frdD - - ko:K00247 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - iNJ661.Rv1555 Fumarate_red_D CMS3_k127_4181141_8 204669.Acid345_1386 5.124e-30 125.0 2EDAV@1|root,33776@2|Bacteria,3Y8RG@57723|Acidobacteria,2JNHN@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - CMS3_k127_4181141_0 760192.Halhy_4150 1.196e-284 901.0 COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,1IR4H@117747|Sphingobacteriia 976|Bacteroidetes E peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - Peptidase_S9 CMS3_k127_4181141_2 661478.OP10G_2391 1.65e-204 656.0 COG1409@1|root,COG3669@1|root,COG1409@2|Bacteria,COG3669@2|Bacteria 2|Bacteria G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,Fucosidase_C,PA14 CMS3_k127_4181141_13 1278073.MYSTI_01759 7.554e-09 66.0 COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales 28221|Deltaproteobacteria K LytTr DNA-binding domain - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_4181141_11 557598.LHK_02475 8.189e-13 74.0 COG4270@1|root,COG4270@2|Bacteria,1N9H8@1224|Proteobacteria,2VXW9@28216|Betaproteobacteria 28216|Betaproteobacteria S DoxX-like family - - - - - - - - - - - - DoxX_2 CMS3_k127_4181141_4 313606.M23134_00734 1.344e-117 419.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia 2|Bacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8 CMS3_k127_4181141_7 1454007.JAUG01000007_gene2173 5.805e-34 134.0 COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,1ITI5@117747|Sphingobacteriia 976|Bacteroidetes L PFAM Transposase IS200 like - - - - - - - - - - - - Y1_Tnp CMS3_k127_4208900_19 1237149.C900_03947 4.311e-28 121.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4208900_20 1237149.C900_00248 4.649e-23 103.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_4208900_7 700598.Niako_1610 1.563e-175 562.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_4208900_9 643867.Ftrac_3083 2.377e-134 434.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47M49@768503|Cytophagia 976|Bacteroidetes G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK CMS3_k127_4208900_11 1237149.C900_00618 3.845e-115 379.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,47PAF@768503|Cytophagia 976|Bacteroidetes G ROK family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK CMS3_k127_4208900_18 1121930.AQXG01000002_gene2085 6.889e-32 125.0 COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1IZVE@117747|Sphingobacteriia 976|Bacteroidetes S Haemolytic - - - ko:K08998 - - - - ko00000 - - - Haemolytic CMS3_k127_4208900_1 1237149.C900_05718 0.0 1448.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47N25@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_4208900_16 313606.M23134_04079 1.53e-72 250.0 COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes,47N5H@768503|Cytophagia 976|Bacteroidetes K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI CMS3_k127_4208900_14 1121904.ARBP01000006_gene4066 7.207e-111 368.0 COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47N8Q@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_4208900_10 1121904.ARBP01000007_gene3097 4.592e-121 398.0 COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,47NP1@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N CMS3_k127_4208900_15 411154.GFO_2753 6.45e-86 300.0 COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,1HXGA@117743|Flavobacteriia 976|Bacteroidetes E Peptidase M14 - - - - - - - - - - - - Peptidase_M14 CMS3_k127_4208900_13 1237149.C900_00456 5.361e-111 361.0 COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,47KEV@768503|Cytophagia 976|Bacteroidetes I Domain of unknown function (DUF4159) - - - - - - - - - - - - DUF4159 CMS3_k127_4208900_0 1237149.C900_03347 0.0 1477.0 COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia 976|Bacteroidetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge CMS3_k127_4208900_4 1237149.C900_04771 3.046e-203 644.0 COG1057@1|root,COG1057@2|Bacteria,4NEIR@976|Bacteroidetes,47KX5@768503|Cytophagia 976|Bacteroidetes H Nicotinate-nucleotide adenylyltransferase - - - - - - - - - - - - - CMS3_k127_4208900_6 1237149.C900_04772 2.711e-177 565.0 COG0025@1|root,COG0025@2|Bacteria,4NFHG@976|Bacteroidetes,47KAJ@768503|Cytophagia 976|Bacteroidetes P NhaP-type Na H and K H nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger CMS3_k127_4208900_5 1237149.C900_04657 1.287e-181 578.0 COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,47NFV@768503|Cytophagia 976|Bacteroidetes U Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF CMS3_k127_4208900_8 1237149.C900_03053 8.141e-169 538.0 COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,47NZ3@768503|Cytophagia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 CMS3_k127_4208900_17 1237149.C900_04778 6.211e-32 134.0 2DBBT@1|root,2Z8AC@2|Bacteria,4NIRZ@976|Bacteroidetes,47T15@768503|Cytophagia 976|Bacteroidetes S Putative MetA-pathway of phenol degradation - - - - - - - - - - - - Phenol_MetA_deg CMS3_k127_4208900_3 1121904.ARBP01000002_gene6933 7.542e-243 761.0 COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47K1E@768503|Cytophagia 976|Bacteroidetes IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C CMS3_k127_4208900_2 1237149.C900_05664 2.537e-286 882.0 COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,47JZJ@768503|Cytophagia 976|Bacteroidetes O TIGRFAM FeS assembly protein SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 CMS3_k127_4208900_12 1124780.ANNU01000012_gene3907 3.264e-112 364.0 COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes,47N88@768503|Cytophagia 976|Bacteroidetes O TIGRFAM FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran CMS3_k127_4252657_0 1237149.C900_04955 1.252e-82 280.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47K6G@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4252657_3 1237149.C900_05634 2.132e-35 143.0 COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,47UM2@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg CMS3_k127_4252657_1 313606.M23134_03067 4.14e-55 211.0 COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,47QZ2@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_4252657_5 485913.Krac_5768 1.042e-15 89.0 COG0412@1|root,COG0412@2|Bacteria,2G8GH@200795|Chloroflexi 200795|Chloroflexi Q Alpha/beta hydrolase family - - - - - - - - - - - - - CMS3_k127_4252657_2 1239962.C943_03877 5.993e-42 166.0 COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - CarbopepD_reg_2,CarboxypepD_reg,PD40 CMS3_k127_4252657_4 32057.KB217478_gene3197 1.105e-16 93.0 COG3386@1|root,COG3386@2|Bacteria,1G7CY@1117|Cyanobacteria,1HNRZ@1161|Nostocales 1117|Cyanobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - CMS3_k127_4260572_0 313606.M23134_06281 3.278e-75 277.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NSC3@976|Bacteroidetes,47S66@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,TPR_2 CMS3_k127_4278296_3 861299.J421_1374 2.444e-41 159.0 COG2423@1|root,COG2423@2|Bacteria 2|Bacteria E ornithine cyclodeaminase activity ocd2 - 1.4.1.1,1.5.1.25,4.3.1.12 ko:K01750,ko:K18258,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 - R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000,ko04147 - - - OCD_Mu_crystall CMS3_k127_4278296_0 929556.Solca_1500 1.214e-122 399.0 COG2207@1|root,COG4275@1|root,COG2207@2|Bacteria,COG4275@2|Bacteria,4NIZN@976|Bacteroidetes,1IQES@117747|Sphingobacteriia 976|Bacteroidetes K Chromate resistance exported protein - - - - - - - - - - - - Chrome_Resist,HTH_18 CMS3_k127_4278296_1 234267.Acid_3893 3.862e-60 215.0 COG3403@1|root,COG3403@2|Bacteria,3Y7H4@57723|Acidobacteria 57723|Acidobacteria S YqcI/YcgG family - - - - - - - - - - - - - CMS3_k127_4278296_4 929562.Emtol_2111 6.877e-28 126.0 COG2207@1|root,COG2207@2|Bacteria,4NHEJ@976|Bacteroidetes,47MRE@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_4278296_5 1184267.A11Q_261 5.653e-25 117.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2MT3E@213481|Bdellovibrionales,2WPAC@28221|Deltaproteobacteria 213481|Bdellovibrionales S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_4278296_7 1202532.FF52_09593 7.43e-13 79.0 COG1680@1|root,COG2976@1|root,COG1680@2|Bacteria,COG2976@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia,2NT82@237|Flavobacterium 976|Bacteroidetes V beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471,TPR_2,TPR_8 CMS3_k127_4278296_6 886377.Murru_2881 1.476e-16 89.0 COG2207@1|root,COG2207@2|Bacteria,4NPKU@976|Bacteroidetes,1I5VB@117743|Flavobacteriia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18,HTH_AraC CMS3_k127_4278296_2 1321778.HMPREF1982_04528 8.295e-45 167.0 COG1247@1|root,COG1247@2|Bacteria,1VJ3A@1239|Firmicutes,25GYK@186801|Clostridia 186801|Clostridia M Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_4282713_2 1237149.C900_02648 2.501e-67 233.0 COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,47Q1V@768503|Cytophagia 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_4282713_0 1237149.C900_02649 3.803e-84 286.0 COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,47WZW@768503|Cytophagia 976|Bacteroidetes S Excinuclease ABC subunit B - - - - - - - - - - - - ABC2_membrane_2,ABC2_membrane_4 CMS3_k127_4282713_1 1237149.C900_01567 5.943e-83 289.0 COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes 976|Bacteroidetes KT COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - - - - - - - - - - SpoIIE,TPR_12 CMS3_k127_4305786_3 861299.J421_1374 2.824e-34 135.0 COG2423@1|root,COG2423@2|Bacteria 2|Bacteria E ornithine cyclodeaminase activity ocd2 - 1.4.1.1,1.5.1.25,4.3.1.12 ko:K01750,ko:K18258,ko:K19244 ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230 - R00396,R00671 RC00008,RC00354 ko00000,ko00001,ko01000,ko04147 - - - OCD_Mu_crystall CMS3_k127_4305786_0 926549.KI421517_gene873 1.274e-171 549.0 COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,47M3J@768503|Cytophagia 976|Bacteroidetes P TIGRFAM chromate transporter, chromate ion transporter (CHR) family - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp CMS3_k127_4305786_1 1121899.Q764_13000 8.476e-65 237.0 COG3391@1|root,COG3391@2|Bacteria,4NSAP@976|Bacteroidetes,1I8CM@117743|Flavobacteriia,2NVND@237|Flavobacterium 976|Bacteroidetes S amine dehydrogenase activity - - - - - - - - - - - - - CMS3_k127_4305786_2 374847.Kcr_0638 1.258e-53 201.0 arCOG02559@1|root,arCOG02559@2157|Archaea 2157|Archaea P by modhmm - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - CMS3_k127_4322791_2 1237149.C900_01743 1.54e-161 520.0 COG1322@1|root,COG1322@2|Bacteria,4NE04@976|Bacteroidetes,47MZE@768503|Cytophagia 976|Bacteroidetes S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC CMS3_k127_4322791_5 1237149.C900_01745 3.231e-55 196.0 COG0234@1|root,COG0234@2|Bacteria,4NRE1@976|Bacteroidetes,47Q9W@768503|Cytophagia 976|Bacteroidetes O Chaperonin 10 Kd subunit - - - - - - - - - - - - Cpn10 CMS3_k127_4322791_0 1121373.KB903662_gene75 3.96e-202 635.0 COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family rocD - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_4322791_8 880070.Cycma_2670 2.059e-30 123.0 COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,47R5P@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 CMS3_k127_4322791_9 867902.Ornrh_1327 2.33e-29 118.0 COG0267@1|root,COG0267@2|Bacteria,4NURM@976|Bacteroidetes,1I55D@117743|Flavobacteriia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 CMS3_k127_4322791_10 1237149.C900_01753 9.593e-15 76.0 2E359@1|root,32P2Z@2|Bacteria,4NWAD@976|Bacteroidetes,47SNB@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4295) - - - - - - - - - - - - DUF4295 CMS3_k127_4322791_3 1237149.C900_01754 2.188e-155 496.0 COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,47JVI@768503|Cytophagia 976|Bacteroidetes U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N CMS3_k127_4322791_7 1237149.C900_01757 4.916e-38 151.0 28JHY@1|root,2Z9BE@2|Bacteria,4NVN1@976|Bacteroidetes,47SUR@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4322791_1 866536.Belba_0212 7.54e-187 592.0 COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 CMS3_k127_4322791_4 1124780.ANNU01000018_gene1630 5.478e-141 464.0 COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,47JYH@768503|Cytophagia 976|Bacteroidetes S Belongs to the BshC family bshC - - ko:K22136 - - - - ko00000 - - - BshC CMS3_k127_4322791_6 873517.HMPREF1977_0402 8.752e-42 160.0 COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia,1ERZI@1016|Capnocytophaga 976|Bacteroidetes H 5-formyltetrahydrofolate cyclo-ligase ygfA - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig CMS3_k127_4323436_8 700598.Niako_6250 6.893e-19 89.0 COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 CMS3_k127_4323436_4 313603.FB2170_12051 1.761e-57 207.0 COG3124@1|root,COG3124@2|Bacteria,4NHQK@976|Bacteroidetes,1I1CI@117743|Flavobacteriia,2PGUK@252356|Maribacter 976|Bacteroidetes S Acyl carrier protein phosphodiesterase acpH - - - - - - - - - - - ACP_PD CMS3_k127_4323436_0 1237149.C900_04969 0.0 1186.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia 976|Bacteroidetes G Sortilin, neurotensin receptor 3, - - - - - - - - - - - - BNR,BNR_6,Sortilin-Vps10 CMS3_k127_4323436_6 1237149.C900_05473 1.284e-27 117.0 2EPSB@1|root,33HCU@2|Bacteria,4NYPB@976|Bacteroidetes,47SU9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4323436_3 1121904.ARBP01000002_gene6773 6.214e-109 364.0 COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47MN1@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF819) - - - - - - - - - - - - DUF819 CMS3_k127_4323436_2 1237149.C900_05712 1.115e-113 376.0 COG4301@1|root,COG4301@2|Bacteria,4NEFC@976|Bacteroidetes,47KDA@768503|Cytophagia 976|Bacteroidetes S Histidine-specific methyltransferase, SAM-dependent egtD - - - - - - - - - - - Methyltransf_33 CMS3_k127_4323436_1 1237149.C900_05713 4.932e-164 526.0 COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,47JJI@768503|Cytophagia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 egtB - - - - - - - - - - - DinB_2,FGE-sulfatase CMS3_k127_4323436_5 929562.Emtol_2719 1.256e-37 146.0 2DM4T@1|root,31QCU@2|Bacteria,4P9NM@976|Bacteroidetes,47RQN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4323436_9 985255.APHJ01000031_gene2770 7.159e-14 74.0 COG0784@1|root,COG0784@2|Bacteria,4NSX5@976|Bacteroidetes,1I4D8@117743|Flavobacteriia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_4323436_7 1121904.ARBP01000009_gene4229 4.52e-27 119.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,47WA7@768503|Cytophagia 976|Bacteroidetes S Transposase - - - - - - - - - - - - - CMS3_k127_4358026_3 522772.Dacet_1168 8.941e-26 120.0 COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria 2|Bacteria T protein histidine kinase activity - - - - - - - - - - - - HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg CMS3_k127_4358026_2 509191.AEDB02000108_gene1670 9.262e-45 177.0 COG4191@1|root,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,24A78@186801|Clostridia,3WHKR@541000|Ruminococcaceae 186801|Clostridia T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 CMS3_k127_4358026_1 243231.GSU2915 5.335e-102 348.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales 28221|Deltaproteobacteria T Domains REC, sigma54 interaction, HTH8 - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_4358026_6 1232437.KL662031_gene2539 0.0001992 49.0 COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG5000@2|Bacteria,1NWAF@1224|Proteobacteria,430TW@68525|delta/epsilon subdivisions,2X8P8@28221|Deltaproteobacteria,2MPQ5@213118|Desulfobacterales 28221|Deltaproteobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS,Response_reg CMS3_k127_4358026_5 926554.KI912671_gene251 1.203e-17 90.0 COG4704@1|root,COG4704@2|Bacteria 2|Bacteria - - - - - ko:K14645 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8 CMS3_k127_4358026_0 1123277.KB893243_gene266 4.722e-162 549.0 COG3227@1|root,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,47MX4@768503|Cytophagia 976|Bacteroidetes E Thermolysin metallopeptidase, catalytic domain npr - 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,MAM,PepSY,Peptidase_M4,Peptidase_M4_C,fn3 CMS3_k127_4358026_4 1519464.HY22_13055 2.651e-23 117.0 COG0265@1|root,COG0366@1|root,COG0265@2|Bacteria,COG0366@2|Bacteria 2|Bacteria G hydrolase activity, hydrolyzing O-glycosyl compounds - - 3.4.21.50 ko:K01337 - - - - ko00000,ko01000,ko01002 - - - Alpha-amylase CMS3_k127_437911_3 1237149.C900_00885 4.474e-181 583.0 COG3975@1|root,COG3975@2|Bacteria,4NE4D@976|Bacteroidetes,47NWB@768503|Cytophagia 976|Bacteroidetes S M61 glycyl aminopeptidase - - - - - - - - - - - - Peptidase_M61 CMS3_k127_437911_9 1237149.C900_04851 4.986e-26 115.0 2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,47R71@768503|Cytophagia 976|Bacteroidetes S Putative lumazine-binding - - - - - - - - - - - - Lumazine_bd_2 CMS3_k127_437911_7 1123508.JH636448_gene7571 1.187e-60 215.0 COG2129@1|root,COG2129@2|Bacteria,2J1K1@203682|Planctomycetes 203682|Planctomycetes S Metallophosphoesterase, calcineurin superfamily - - - - - - - - - - - - Metallophos,Metallophos_2 CMS3_k127_437911_8 316067.Geob_2070 9.775e-43 164.0 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,42VMX@68525|delta/epsilon subdivisions,2WS5W@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q ubiE/COQ5 methyltransferase family - - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 CMS3_k127_437911_6 746697.Aeqsu_1810 1.15e-91 308.0 COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1I0VV@117743|Flavobacteriia 976|Bacteroidetes Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 CMS3_k127_437911_0 1237149.C900_05255 5.193e-287 916.0 COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD,SBBP CMS3_k127_437911_10 1317122.ATO12_00115 3.519e-07 58.0 2BU8Y@1|root,32PIF@2|Bacteria,4PAKP@976|Bacteroidetes,1ICHN@117743|Flavobacteriia,2YM2X@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_437911_1 1288963.ADIS_1925 2.482e-205 645.0 COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_437911_2 1123240.ATVO01000010_gene703 1.382e-195 625.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2K9UC@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 CMS3_k127_437911_4 926549.KI421517_gene2416 1.619e-146 492.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_437911_5 313606.M23134_07780 4.847e-132 434.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_4379211_4 1250006.JHZZ01000001_gene1046 1.307e-28 115.0 COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1HZ0I@117743|Flavobacteriia,3VW5Y@52959|Polaribacter 976|Bacteroidetes S Hexapeptide repeat of succinyl-transferase - - 2.3.1.201 ko:K13018 ko00520,map00520 - R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 - - - Hexapep,Hexapep_2 CMS3_k127_4379211_2 1124780.ANNU01000036_gene72 5.462e-132 430.0 COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47KX7@768503|Cytophagia 976|Bacteroidetes M Belongs to the DegT DnrJ EryC1 family degT - - - - - - - - - - - DegT_DnrJ_EryC1 CMS3_k127_4379211_0 1237149.C900_02797 2.491e-192 608.0 COG0677@1|root,COG0677@2|Bacteria,4NDTW@976|Bacteroidetes,47JKM@768503|Cytophagia 976|Bacteroidetes M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K02474,ko:K13015 ko00520,map00520 - R00421,R06894 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N CMS3_k127_4379211_1 237368.SCABRO_02618 4.796e-143 460.0 COG0451@1|root,COG0451@2|Bacteria,2IXJ5@203682|Planctomycetes 203682|Planctomycetes M epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd CMS3_k127_4379211_3 1123058.KB894240_gene1984 4.631e-57 203.0 COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1I20V@117743|Flavobacteriia 976|Bacteroidetes M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom CMS3_k127_4397336_2 761193.Runsl_0002 3.155e-23 106.0 COG5653@1|root,COG5653@2|Bacteria,4NQN5@976|Bacteroidetes,47Q2X@768503|Cytophagia 976|Bacteroidetes M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6 CMS3_k127_4397336_1 1121104.AQXH01000001_gene1691 2.256e-138 452.0 COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes,1IP78@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase, M28 - - - - - - - - - - - - Peptidase_M28 CMS3_k127_4397336_0 1121904.ARBP01000012_gene1252 3.024e-156 503.0 COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,47Y1Q@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4468338_3 1121904.ARBP01000001_gene5544 1.617e-226 713.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47JCM@768503|Cytophagia 976|Bacteroidetes O Domain of unknown function (DUF5118) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 CMS3_k127_4468338_9 926549.KI421517_gene3612 1.076e-59 212.0 2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,47MR9@768503|Cytophagia 976|Bacteroidetes S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_4468338_1 926549.KI421517_gene3613 1.27e-278 865.0 COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes,47MZ9@768503|Cytophagia 976|Bacteroidetes E Oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N CMS3_k127_4468338_11 1124780.ANNU01000025_gene3397 1.852e-38 151.0 COG0135@1|root,COG0135@2|Bacteria,4NMKY@976|Bacteroidetes,47PJ8@768503|Cytophagia 976|Bacteroidetes E isomerase - - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI CMS3_k127_4468338_4 643867.Ftrac_0476 6.843e-215 670.0 COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,47KX3@768503|Cytophagia 976|Bacteroidetes J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans CMS3_k127_4468338_13 1313421.JHBV01000040_gene2591 1.337e-08 65.0 298K1@1|root,3122S@2|Bacteria,4PGXN@976|Bacteroidetes,1IUN3@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4468338_5 1124780.ANNU01000025_gene3392 9.551e-125 418.0 COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,47KS3@768503|Cytophagia 976|Bacteroidetes O Peptidase S8 and S53 subtilisin kexin sedolisin aprN - - - - - - - - - - - Peptidase_S8 CMS3_k127_4468338_6 1279009.ADICEAN_01971 1.937e-99 328.0 COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,47N3P@768503|Cytophagia 976|Bacteroidetes G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim CMS3_k127_4468338_2 1237149.C900_01230 2.263e-235 751.0 COG1629@1|root,COG4771@2|Bacteria,4PKKT@976|Bacteroidetes,47KRF@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug CMS3_k127_4468338_10 1237149.C900_01234 1.255e-49 183.0 2C093@1|root,34BBZ@2|Bacteria,4P53B@976|Bacteroidetes,47VVT@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4468338_7 1237149.C900_01235 1.887e-73 260.0 2EG6T@1|root,339YP@2|Bacteria,4NXNK@976|Bacteroidetes,47T48@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4468338_0 1237149.C900_04189 0.0 1321.0 COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,47K30@768503|Cytophagia 976|Bacteroidetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV CMS3_k127_4468338_8 1124780.ANNU01000025_gene3349 5.17e-69 245.0 COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,47PQF@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8 CMS3_k127_4490195_8 929562.Emtol_0952 8.902e-46 169.0 COG0414@1|root,COG0414@2|Bacteria,4NFT9@976|Bacteroidetes,47MNB@768503|Cytophagia 976|Bacteroidetes H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase CMS3_k127_4490195_5 1237149.C900_04466 4.548e-142 454.0 COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,47KUD@768503|Cytophagia 976|Bacteroidetes G PFAM Starch synthase catalytic domain glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5 CMS3_k127_4490195_10 1185876.BN8_04630 2.189e-28 130.0 28J4T@1|root,2Z90P@2|Bacteria,4NHUC@976|Bacteroidetes,47RDH@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4270) - - - - - - - - - - - - DUF4270 CMS3_k127_4490195_0 1237149.C900_04468 3.317e-315 973.0 COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,47KVG@768503|Cytophagia 976|Bacteroidetes M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS CMS3_k127_4490195_6 643867.Ftrac_2235 1.094e-66 233.0 COG1250@1|root,COG1250@2|Bacteria,4NWYY@976|Bacteroidetes,47VDX@768503|Cytophagia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - 3HCDH CMS3_k127_4490195_7 1237149.C900_04481 5.384e-49 177.0 COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,47QE4@768503|Cytophagia 976|Bacteroidetes J TIGRFAM endoribonuclease L-PSP yjgF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP CMS3_k127_4490195_11 1120965.AUBV01000008_gene2102 2.366e-22 102.0 2EEHV@1|root,338BQ@2|Bacteria,4PMKH@976|Bacteroidetes,47WRF@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4490195_2 471854.Dfer_4262 4.187e-191 609.0 COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,4NEED@976|Bacteroidetes,47K3J@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c CMS3_k127_4490195_12 1124780.ANNU01000017_gene1878 1.938e-12 68.0 2E4W4@1|root,32ZQB@2|Bacteria,4NUZZ@976|Bacteroidetes,47RZI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4490195_4 1237149.C900_04486 8.929e-166 529.0 COG0686@1|root,COG0686@2|Bacteria,4NF46@976|Bacteroidetes,47KRS@768503|Cytophagia 976|Bacteroidetes E Alanine dehydrogenase PNT, N-terminal domain - - - - - - - - - - - - AlaDh_PNT_C,AlaDh_PNT_N CMS3_k127_4490195_1 1237149.C900_03232 2.354e-245 767.0 COG1158@1|root,COG1158@2|Bacteria,4NEFP@976|Bacteroidetes,47JWD@768503|Cytophagia 976|Bacteroidetes K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind CMS3_k127_4490195_3 1120965.AUBV01000003_gene325 6.324e-191 604.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,47JAB@768503|Cytophagia 976|Bacteroidetes J tRNA synthetase class II core domain (G, H, P, S and T) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b CMS3_k127_4490195_9 1237149.C900_03228 1.2e-31 126.0 COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,47JBG@768503|Cytophagia 976|Bacteroidetes E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain pep GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N CMS3_k127_4497243_4 1121904.ARBP01000002_gene7293 5.293e-113 380.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4497243_11 765914.ThisiDRAFT_1569 4.881e-28 116.0 COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,1S83W@1236|Gammaproteobacteria 1236|Gammaproteobacteria K addiction module antidote protein, HigA family ybaQ GO:0008150,GO:0009636,GO:0042221,GO:0050896 - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 CMS3_k127_4497243_13 1150600.ADIARSV_4348 5.65e-09 57.0 COG3549@1|root,COG3549@2|Bacteria,4NW85@976|Bacteroidetes 976|Bacteroidetes S PFAM Plasmid maintenance system killer - - - ko:K07334 - - - - ko00000,ko02048 - - - HigB-like_toxin CMS3_k127_4497243_8 1049564.TevJSym_aq00670 8.005e-91 301.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfA - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr CMS3_k127_4497243_9 1049564.TevJSym_aq00680 7.101e-79 269.0 COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfE2 - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr CMS3_k127_4497243_10 1049564.TevJSym_aq00690 8.571e-51 188.0 COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport - - - - - - - - - - - - FMN_bind CMS3_k127_4497243_6 1049564.TevJSym_aq00700 1.544e-104 349.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE CMS3_k127_4497243_2 945713.IALB_0253 9.925e-122 405.0 COG4656@1|root,COG4656@2|Bacteria 2|Bacteria C electron transfer activity rnfC - 1.2.7.3 ko:K00176,ko:K03615 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 M00009,M00011,M00173,M00620 R01197 RC00004,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - Complex1_51K,Fer4,Fer4_10,Fer4_8,RnfC_N,SLBB CMS3_k127_4497243_1 1283300.ATXB01000001_gene1162 2.86e-138 488.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales 135618|Methylococcales C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C CMS3_k127_4497243_7 765910.MARPU_10745 4.395e-94 316.0 COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria,1WWC5@135613|Chromatiales 135613|Chromatiales C Fe-S cluster - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4 CMS3_k127_4497243_5 1049564.TevJSym_bb00030 4.576e-110 388.0 COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria 1224|Proteobacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - TPP_enzyme_C CMS3_k127_4497243_3 1049564.TevJSym_bb00040 1.565e-116 383.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C CMS3_k127_4497243_0 1049564.TevJSym_bb00050 1.179e-255 802.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N CMS3_k127_4497243_12 1120966.AUBU01000001_gene1130 1.528e-11 68.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47QEI@768503|Cytophagia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - Guanylate_cyc,TPR_17,TPR_8 CMS3_k127_4497243_14 399741.Spro_2557 6.263e-08 54.0 COG3832@1|root,COG3832@2|Bacteria,1RHJJ@1224|Proteobacteria,1S850@1236|Gammaproteobacteria,3ZZVK@613|Serratia 1236|Gammaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 CMS3_k127_4549083_30 714943.Mucpa_2189 5.724e-05 46.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_19,HTH_26,HTH_3,HTH_31 CMS3_k127_4549083_29 1500281.JQKZ01000015_gene2145 6.168e-07 54.0 2AAAU@1|root,30ZKF@2|Bacteria,4PDWW@976|Bacteroidetes,1IEA8@117743|Flavobacteriia,3ZT19@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4549083_27 313606.M23134_02438 7.984e-28 113.0 COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHB@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_4549083_25 1237149.C900_04701 1.014e-45 169.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_4549083_0 1249997.JHZW01000003_gene3776 0.0 1609.0 COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI8X@252356|Maribacter 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_4549083_16 1034943.BN1094_00038 3.89e-111 380.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,1JC52@118969|Legionellales 118969|Legionellales S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 CMS3_k127_4549083_8 869210.Marky_1927 1.456e-155 505.0 COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E COG0076 Glutamate decarboxylase and related PLP-dependent - - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC CMS3_k127_4549083_11 991.IW20_11645 2.895e-123 399.0 COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1HZKX@117743|Flavobacteriia 976|Bacteroidetes S phenazine biosynthesis protein, PhzF family - - - - - - - - - - - - PhzC-PhzF CMS3_k127_4549083_23 1206725.BAFU01000029_gene2997 1.545e-63 231.0 COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria,4FXD4@85025|Nocardiaceae 201174|Actinobacteria C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N CMS3_k127_4549083_6 1121904.ARBP01000053_gene476 3.681e-168 539.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47K4A@768503|Cytophagia 976|Bacteroidetes C PFAM Aldehyde dehydrogenase sad - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_4549083_7 1237149.C900_04914 3.842e-163 518.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47JEN@768503|Cytophagia 976|Bacteroidetes S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 CMS3_k127_4549083_19 1237149.C900_04918 3.89e-93 314.0 COG1090@1|root,COG1090@2|Bacteria,4NINM@976|Bacteroidetes,47KA1@768503|Cytophagia 976|Bacteroidetes S PFAM NAD dependent epimerase dehydratase family - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase CMS3_k127_4549083_12 1124780.ANNU01000006_gene2951 2.386e-122 396.0 COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,47M0E@768503|Cytophagia 976|Bacteroidetes S Belongs to the LOG family fmt2 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox CMS3_k127_4549083_15 1237149.C900_04921 2.913e-111 368.0 COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,47MKU@768503|Cytophagia 976|Bacteroidetes M Transglycosylase SLT domain mltD_2 - - - - - - - - - - - SLT CMS3_k127_4549083_1 1237149.C900_04576 0.0 1513.0 COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran CMS3_k127_4549083_4 643867.Ftrac_2548 5.724e-174 555.0 COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,47K1Q@768503|Cytophagia 976|Bacteroidetes C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS3_k127_4549083_18 1237149.C900_04581 2.705e-101 340.0 COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase CMS3_k127_4549083_14 1237149.C900_04582 9.97e-114 371.0 COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_4549083_26 313606.M23134_02534 1.649e-37 144.0 2D41J@1|root,32TG2@2|Bacteria,4NTNX@976|Bacteroidetes,47RJ7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4549083_22 1237149.C900_04584 4.281e-84 286.0 COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes,47P8G@768503|Cytophagia 976|Bacteroidetes S Putative cyclase - - - - - - - - - - - - Cyclase CMS3_k127_4549083_13 1121904.ARBP01000033_gene3168 2.77e-120 397.0 COG0635@1|root,COG0635@2|Bacteria,4NFEE@976|Bacteroidetes,47JXR@768503|Cytophagia 976|Bacteroidetes H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM CMS3_k127_4549083_24 1124780.ANNU01000006_gene2942 4.72e-62 226.0 COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,47M4P@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 4 mraY2 - - - - - - - - - - - Glycos_transf_4 CMS3_k127_4549083_10 1237149.C900_04588 3.999e-124 402.0 COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,47JYP@768503|Cytophagia 976|Bacteroidetes H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 CMS3_k127_4549083_20 1237149.C900_04589 2.002e-91 310.0 COG0226@1|root,COG0226@2|Bacteria,4NKND@976|Bacteroidetes,47PVA@768503|Cytophagia 976|Bacteroidetes P Type IX secretion system membrane protein PorP/SprF - - - - - - - - - - - - PorP_SprF CMS3_k127_4549083_3 1124780.ANNU01000006_gene2938 4.26e-192 602.0 COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,47KHB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated lipoprotein GldK gldK - - - - - - - - - - - FGE-sulfatase CMS3_k127_4549083_17 1279009.ADICEAN_01025 2.46e-110 363.0 28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,47MA3@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated protein GldL gldL - - - - - - - - - - - - CMS3_k127_4549083_5 1237149.C900_04592 2.262e-170 549.0 28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated protein GldM gldM - - - - - - - - - - - GldM_C,GldM_N CMS3_k127_4549083_21 1124780.ANNU01000006_gene2935 2.014e-84 289.0 2C97B@1|root,2ZAEJ@2|Bacteria,4NEK0@976|Bacteroidetes,47MC2@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility associated protien GldN - - - - - - - - - - - - - CMS3_k127_4549083_2 1237149.C900_04594 1.62e-213 678.0 COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,47JXP@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N CMS3_k127_4549083_9 643867.Ftrac_2561 1.673e-147 476.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia 976|Bacteroidetes M Penicillin binding protein transpeptidase pbpB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS3_k127_4579407_1 926561.KB900617_gene1617 2.214e-142 458.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,3WAN4@53433|Halanaerobiales 186801|Clostridia C PFAM aldo keto reductase - - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red CMS3_k127_4579407_2 411154.GFO_0032 1.773e-130 426.0 COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,1I0YN@117743|Flavobacteriia 976|Bacteroidetes G Arabinogalactan endo-beta-1,4-galactanase - - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Glyco_hydro_53 CMS3_k127_4579407_0 760192.Halhy_6203 5.137e-243 765.0 COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,1IWXN@117747|Sphingobacteriia 976|Bacteroidetes G Alpha-amylase domain - - 3.2.1.135 ko:K21575 - - - - ko00000,ko01000 - GH13 - Alpha-amylase,Cyc-maltodext_C,Cyc-maltodext_N CMS3_k127_4579407_3 509635.N824_10775 2.469e-32 129.0 COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1IP7K@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - - - - - - - - - - - CHB_HEX_C_1,DUF4982,Fn3_assoc,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CMS3_k127_4583540_4 118173.KB235914_gene3704 1.108e-23 110.0 COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales 1117|Cyanobacteria KLT PFAM Protein kinase domain - - - - - - - - - - - - GUN4,Pkinase,TPR_1,TPR_11,WD40 CMS3_k127_4583540_1 1237149.C900_03960 6.525e-121 399.0 COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,47XWD@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III, delta' subunit holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 CMS3_k127_4583540_3 1237149.C900_03958 3.201e-84 288.0 COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia 976|Bacteroidetes O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase CMS3_k127_4583540_2 1237149.C900_03957 1.396e-118 387.0 COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,47MQV@768503|Cytophagia 976|Bacteroidetes M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind CMS3_k127_4583540_0 1089550.ATTH01000001_gene2230 1.102e-141 463.0 COG0733@1|root,COG0733@2|Bacteria,4NGQ5@976|Bacteroidetes,1FJPU@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes P Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF CMS3_k127_4585487_16 468059.AUHA01000002_gene563 9.149e-75 276.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia 976|Bacteroidetes K Tetratricopeptide repeat - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_4585487_19 1408473.JHXO01000009_gene3394 5.642e-43 169.0 arCOG10603@1|root,32SV6@2|Bacteria,4NJM3@976|Bacteroidetes,2FR7H@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4585487_10 1047013.AQSP01000114_gene680 5.08e-153 512.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4585487_1 1120965.AUBV01000001_gene3486 0.0 1187.0 COG2866@1|root,COG2866@2|Bacteria,4NGIE@976|Bacteroidetes,47N2M@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 CMS3_k127_4585487_6 388413.ALPR1_06240 1.362e-196 624.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47N92@768503|Cytophagia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_4585487_7 1279009.ADICEAN_00324 1.393e-184 595.0 COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47MPR@768503|Cytophagia 976|Bacteroidetes S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 CMS3_k127_4585487_23 1536772.R70723_14615 3.887e-22 102.0 COG2819@1|root,COG2819@2|Bacteria,1UY7T@1239|Firmicutes,4IPTC@91061|Bacilli,2763I@186822|Paenibacillaceae 91061|Bacilli S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase CMS3_k127_4585487_22 189425.PGRAT_14365 2.068e-22 104.0 COG2819@1|root,COG2819@2|Bacteria,1UY7T@1239|Firmicutes,4IPTC@91061|Bacilli,2763I@186822|Paenibacillaceae 91061|Bacilli S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase CMS3_k127_4585487_3 1237149.C900_05170 5.204e-284 881.0 COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47MDS@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran,Peptidase_C39 CMS3_k127_4585487_25 745718.JADT01000014_gene127 1.202e-09 66.0 COG3637@1|root,COG3637@2|Bacteria,4NPFD@976|Bacteroidetes,1I2KB@117743|Flavobacteriia 976|Bacteroidetes M Autotransporter beta-domain - - - - - - - - - - - - OMP_b-brl CMS3_k127_4585487_24 1123037.AUDE01000018_gene2852 2.571e-11 67.0 2E6UP@1|root,331EC@2|Bacteria,4NUYV@976|Bacteroidetes,1I59A@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4585487_18 335543.Sfum_3431 4.42e-58 211.0 COG0300@1|root,COG0300@2|Bacteria,1P42K@1224|Proteobacteria,42PPU@68525|delta/epsilon subdivisions,2WM15@28221|Deltaproteobacteria,2MQSQ@213462|Syntrophobacterales 28221|Deltaproteobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short CMS3_k127_4585487_9 1239962.C943_01714 1.446e-154 492.0 COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,47JPY@768503|Cytophagia 976|Bacteroidetes I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA CMS3_k127_4585487_12 1237149.C900_00003 2.245e-125 406.0 COG0491@1|root,COG0491@2|Bacteria,4NE98@976|Bacteroidetes,47JCR@768503|Cytophagia 976|Bacteroidetes S PFAM Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_4585487_17 866536.Belba_3319 5.646e-67 236.0 COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,47JZ5@768503|Cytophagia 976|Bacteroidetes S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin CMS3_k127_4585487_2 1237149.C900_00005 0.0 1075.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,47K5S@768503|Cytophagia 976|Bacteroidetes E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N CMS3_k127_4585487_5 1237149.C900_00016 6.359e-197 622.0 COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b CMS3_k127_4585487_20 313606.M23134_00982 1.346e-26 121.0 COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NQHU@976|Bacteroidetes,47R06@768503|Cytophagia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,TPR_12,TPR_8 CMS3_k127_4585487_0 1121012.AUKX01000013_gene2182 0.0 1561.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,1HZ2Z@117743|Flavobacteriia,23H0F@178469|Arenibacter 976|Bacteroidetes QU COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 CMS3_k127_4585487_8 382464.ABSI01000020_gene244 5.77e-169 548.0 COG0591@1|root,COG0591@2|Bacteria,46UFJ@74201|Verrucomicrobia,2IVV1@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Sodium:solute symporter family - - - - - - - - - - - - SSF CMS3_k127_4585487_26 643867.Ftrac_1599 1.364e-09 62.0 2BV0E@1|root,32QD0@2|Bacteria,4PBZ5@976|Bacteroidetes,47WJJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4585487_15 1237149.C900_00026 2.08e-75 263.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - CMS3_k127_4585487_4 1237149.C900_00028 7.004e-217 693.0 COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 CMS3_k127_4585487_13 714943.Mucpa_4707 7.947e-92 310.0 COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1IP8N@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 CMS3_k127_4585487_14 153721.MYP_897 6.956e-86 292.0 2CFX6@1|root,32S2Q@2|Bacteria,4NTW8@976|Bacteroidetes,47VJ9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4585487_11 926549.KI421517_gene3363 6.235e-140 454.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia 976|Bacteroidetes EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 CMS3_k127_4586223_23 1121904.ARBP01000006_gene3681 3.582e-37 154.0 COG3419@1|root,COG4447@1|root,COG4932@1|root,COG5184@1|root,COG3419@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,4NNEI@976|Bacteroidetes 976|Bacteroidetes DZ Putative metal-binding motif - - - - - - - - - - - - Cu-binding_MopE,DUF1566 CMS3_k127_4586223_30 1123057.P872_04760 3.938e-12 78.0 COG3291@1|root,COG5498@1|root,COG3291@2|Bacteria,COG5498@2|Bacteria,4PPR2@976|Bacteroidetes,47YQN@768503|Cytophagia 976|Bacteroidetes G Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_4586223_4 1168034.FH5T_15140 1.08e-192 616.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia 976|Bacteroidetes M Psort location CytoplasmicMembrane, score 10.00 algI - - - - - - - - - - - MBOAT CMS3_k127_4586223_13 1168034.FH5T_15135 1.045e-100 342.0 COG2755@1|root,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,2FN21@200643|Bacteroidia 976|Bacteroidetes E COG NOG14456 non supervised orthologous group - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2,LysM CMS3_k127_4586223_12 1168034.FH5T_15130 2.672e-106 362.0 COG2755@1|root,COG2755@2|Bacteria,4NHT6@976|Bacteroidetes,2G37X@200643|Bacteroidia 976|Bacteroidetes E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 CMS3_k127_4586223_17 1121129.KB903370_gene94 6.621e-69 252.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,2FM5V@200643|Bacteroidia,22VZV@171551|Porphyromonadaceae 976|Bacteroidetes M transglycosylase mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS3_k127_4586223_31 1408473.JHXO01000010_gene3542 4.022e-12 68.0 2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,2FVW5@200643|Bacteroidia 976|Bacteroidetes S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 CMS3_k127_4586223_19 1232437.KL661966_gene3144 5.233e-43 163.0 2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales 28221|Deltaproteobacteria S DGC domain - - - - - - - - - - - - DGC CMS3_k127_4586223_24 1265505.ATUG01000001_gene4389 4.698e-36 143.0 COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria,2MM35@213118|Desulfobacterales 28221|Deltaproteobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_4586223_10 518766.Rmar_1990 3.161e-128 419.0 COG4257@1|root,COG4257@2|Bacteria 2|Bacteria V antibiotic catabolic process - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - DUF5011 CMS3_k127_4586223_3 1124780.ANNU01000030_gene1156 4.863e-218 695.0 COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,Transglut_core CMS3_k127_4586223_8 1124780.ANNU01000030_gene1155 9.924e-132 441.0 COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_4586223_25 643867.Ftrac_2119 1.558e-30 121.0 COG0053@1|root,COG0053@2|Bacteria,4NVGY@976|Bacteroidetes,47SZY@768503|Cytophagia 976|Bacteroidetes P manually curated - - - - - - - - - - - - MerC CMS3_k127_4586223_6 1121094.KB894644_gene2241 1.158e-140 458.0 COG0688@1|root,COG0688@2|Bacteria,4NR69@976|Bacteroidetes,2FVV1@200643|Bacteroidia 976|Bacteroidetes I Phosphatidylserine decarboxylase - - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PSDC,PS_Dcarbxylase CMS3_k127_4586223_28 445961.IW15_20125 2.212e-16 84.0 COG4334@1|root,COG4334@2|Bacteria,4NSAC@976|Bacteroidetes,1I4GX@117743|Flavobacteriia,3ZSES@59732|Chryseobacterium 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2255) - - - - - - - - - - - - DUF2255 CMS3_k127_4586223_20 1237149.C900_03337 2.782e-42 161.0 295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,47W1I@768503|Cytophagia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - CMS3_k127_4586223_22 1237149.C900_03336 1.11e-38 146.0 COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,47V9T@768503|Cytophagia 976|Bacteroidetes K Winged helix DNA-binding domain marR - - - - - - - - - - - HTH_34 CMS3_k127_4586223_29 760192.Halhy_1410 2.301e-16 86.0 2DTU1@1|root,33MMF@2|Bacteria,4NWD8@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4586223_11 234267.Acid_3239 6.394e-116 386.0 COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria 234267.Acid_3239|- Q PFAM amidohydrolase - - - - - - - - - - - - - CMS3_k127_4586223_1 1121930.AQXG01000010_gene3099 0.0 1014.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1IQMB@117747|Sphingobacteriia 976|Bacteroidetes O Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 CMS3_k127_4586223_7 1123057.P872_07620 6.901e-138 445.0 COG2010@1|root,COG2010@2|Bacteria,4NMGT@976|Bacteroidetes,47TXQ@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS3_k127_4586223_15 700598.Niako_5193 5.219e-84 307.0 COG0577@1|root,COG0577@2|Bacteria,4P0QD@976|Bacteroidetes,1IUV8@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4586223_9 929703.KE386491_gene1724 2.723e-129 442.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4586223_0 1296416.JACB01000055_gene3646 0.0 1281.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2YHEZ@290174|Aquimarina 976|Bacteroidetes S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_4586223_18 1237149.C900_04902 1.668e-52 201.0 COG0729@1|root,COG0729@2|Bacteria,4NMUN@976|Bacteroidetes,47Y0X@768503|Cytophagia 976|Bacteroidetes M outer membrane protein protective antigen - - - - - - - - - - - - Bac_surface_Ag CMS3_k127_4586223_5 643867.Ftrac_3711 3.698e-164 521.0 COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia 976|Bacteroidetes S UPF0365 protein - - - - - - - - - - - - YdfA_immunity CMS3_k127_4586223_21 1237149.C900_02887 6.482e-39 150.0 COG1030@1|root,COG1030@2|Bacteria,4NW09@976|Bacteroidetes,47S4B@768503|Cytophagia 976|Bacteroidetes O NfeD-like C-terminal, partner-binding - - - - - - - - - - - - NfeD CMS3_k127_4586223_2 1123057.P872_15120 6.211e-255 793.0 COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,47JTQ@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b CMS3_k127_4586223_27 1237149.C900_04730 2.664e-21 108.0 2CJG0@1|root,332HN@2|Bacteria,4NM27@976|Bacteroidetes,47M0N@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4586223_16 1237149.C900_04729 1.58e-82 293.0 COG2067@1|root,COG2067@2|Bacteria,4NFS7@976|Bacteroidetes,47K28@768503|Cytophagia 976|Bacteroidetes I PFAM Outer membrane protein transport protein (OMPP1 FadL TodX) - - - - - - - - - - - - Toluene_X CMS3_k127_4586223_26 575615.HMPREF0670_01400 1.478e-29 124.0 COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,2FM3K@200643|Bacteroidia 976|Bacteroidetes F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI CMS3_k127_4586223_14 1237149.C900_04727 2.148e-96 323.0 COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,47JTZ@768503|Cytophagia 976|Bacteroidetes S DoxX family doxX - - - - - - - - - - - DoxX CMS3_k127_4595128_3 1237149.C900_02591 2.311e-25 110.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4595128_4 1121957.ATVL01000007_gene2106 6.303e-18 98.0 COG0682@1|root,COG0682@2|Bacteria 2|Bacteria M lipoprotein biosynthetic process - - - - - - - - - - - - LGT CMS3_k127_4595128_0 391596.PBAL39_16084 3.03e-146 469.0 COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,1IQSG@117747|Sphingobacteriia 976|Bacteroidetes C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CMS3_k127_4595128_5 1250232.JQNJ01000001_gene871 2.193e-14 78.0 2BIB7@1|root,32CGZ@2|Bacteria,4NQKQ@976|Bacteroidetes,1I2T7@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4595128_2 1123277.KB893195_gene5684 4.643e-31 124.0 COG1695@1|root,COG1695@2|Bacteria,4P6G7@976|Bacteroidetes,47VZ7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_4595128_1 1237149.C900_00837 6.871e-105 368.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4642459_0 269798.CHU_1025 4.615e-26 120.0 COG3047@1|root,COG3047@2|Bacteria,4PM1M@976|Bacteroidetes,47XZM@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_4646717_6 313606.M23134_06058 4.422e-39 147.0 COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia 976|Bacteroidetes EU Dipeptidyl peptidase IV (DPP IV) N-terminal region - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 CMS3_k127_4646717_0 313596.RB2501_05420 5.4e-323 1007.0 COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,1HYJ1@117743|Flavobacteriia 976|Bacteroidetes S Protein related to penicillin acylase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase CMS3_k127_4646717_7 468059.AUHA01000006_gene2965 4.764e-15 81.0 2EHX5@1|root,33BNR@2|Bacteria,4NXNQ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4646717_4 485913.Krac_4939 3.683e-80 275.0 COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi 200795|Chloroflexi S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L CMS3_k127_4646717_3 929556.Solca_2239 3.676e-100 333.0 COG3384@1|root,COG3384@2|Bacteria,4NFGT@976|Bacteroidetes,1IPF1@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - ko:K15777 ko00965,map00965 - R08836 RC00387 ko00000,ko00001,ko01000 - - - LigB CMS3_k127_4646717_1 1237149.C900_01886 7.581e-145 468.0 COG1649@1|root,COG1649@2|Bacteria,4NGFW@976|Bacteroidetes,47T3X@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised BCR, COG1649 - - - - - - - - - - - - CBM9_1,GHL10 CMS3_k127_4646717_2 1237149.C900_01887 2.154e-129 422.0 COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,47NBX@768503|Cytophagia 976|Bacteroidetes Q Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 CMS3_k127_4646717_5 643867.Ftrac_2998 1.548e-48 190.0 COG2885@1|root,COG2885@2|Bacteria,4NU83@976|Bacteroidetes,47VBR@768503|Cytophagia 976|Bacteroidetes M Pfam:DUF3308 - - - - - - - - - - - - OmpA,PorP_SprF CMS3_k127_4689520_2 1150600.ADIARSV_3322 1.737e-84 308.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ0T@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4689520_3 743719.PaelaDRAFT_3760 6.975e-18 87.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase CMS3_k127_4689520_1 1237149.C900_03082 1.201e-149 480.0 COG1064@1|root,COG1064@2|Bacteria,4NJ7A@976|Bacteroidetes,47XCS@768503|Cytophagia 976|Bacteroidetes S Zinc-binding dehydrogenase - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N_2 CMS3_k127_4689520_0 1237149.C900_02140 0.0 1099.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,47JHD@768503|Cytophagia 976|Bacteroidetes G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N CMS3_k127_471951_0 313606.M23134_01886 8.271e-93 311.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47JCM@768503|Cytophagia 976|Bacteroidetes O Domain of unknown function (DUF5118) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 CMS3_k127_471951_3 945713.IALB_2767 1.568e-17 91.0 COG1708@1|root,COG1708@2|Bacteria 2|Bacteria S nucleotidyltransferase activity - - - - - - - - - - - - KNTase_C,NTP_transf_2 CMS3_k127_471951_2 388413.ALPR1_06860 2.957e-55 198.0 COG0517@1|root,COG0517@2|Bacteria,4NNFS@976|Bacteroidetes,47QRM@768503|Cytophagia 976|Bacteroidetes S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS CMS3_k127_471951_1 1121904.ARBP01000002_gene7127 4.793e-81 283.0 COG3386@1|root,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - - - - - - - - - - - SGL CMS3_k127_471951_4 471854.Dfer_2270 9.533e-11 64.0 2C34F@1|root,2ZA5Y@2|Bacteria,4NGPA@976|Bacteroidetes,47MYC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_474891_37 388413.ALPR1_04493 6.443e-45 167.0 COG0394@1|root,COG0394@2|Bacteria,4NNQZ@976|Bacteroidetes,47R52@768503|Cytophagia 976|Bacteroidetes T Low molecular weight phosphotyrosine protein phosphatase ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc CMS3_k127_474891_12 1237149.C900_03744 5.663e-132 433.0 COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,47JAD@768503|Cytophagia 976|Bacteroidetes E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase CMS3_k127_474891_8 1237149.C900_03745 5.212e-162 514.0 COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,47KNQ@768503|Cytophagia 976|Bacteroidetes G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase CMS3_k127_474891_42 1237149.C900_03746 5.173e-14 75.0 2DRQJ@1|root,33CMW@2|Bacteria,4NYAM@976|Bacteroidetes,47T3Q@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_474891_36 1237149.C900_03747 3.293e-51 186.0 2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,47PWR@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_474891_25 926549.KI421517_gene2900 1.129e-73 253.0 COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,47P6H@768503|Cytophagia 976|Bacteroidetes D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 CMS3_k127_474891_22 643867.Ftrac_0142 3.133e-95 332.0 COG0790@1|root,COG2885@1|root,COG0790@2|Bacteria,COG2885@2|Bacteria,4NHCE@976|Bacteroidetes,47NZ4@768503|Cytophagia 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_474891_18 1237149.C900_03750 2.644e-111 364.0 COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia 976|Bacteroidetes H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran CMS3_k127_474891_26 1237149.C900_03751 3.873e-71 247.0 2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,47PC8@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain porT - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_474891_20 616991.JPOO01000003_gene2136 1.112e-110 363.0 COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,1HY5P@117743|Flavobacteriia,23GJU@178469|Arenibacter 976|Bacteroidetes S KR domain ydfG - - - - - - - - - - - adh_short CMS3_k127_474891_32 1237149.C900_03753 1.364e-59 213.0 COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia 976|Bacteroidetes S PFAM phospholipase Carboxylesterase - - - - - - - - - - - - Abhydrolase_2,FSH1 CMS3_k127_474891_38 143224.JQMD01000002_gene2341 5.609e-42 159.0 COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia 976|Bacteroidetes F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 CMS3_k127_474891_6 1237149.C900_03765 1.783e-186 593.0 COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47MT4@768503|Cytophagia 976|Bacteroidetes E Saccharopine dehydrogenase - - 1.5.1.10,1.5.1.7 ko:K00290,ko:K00293 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R02315 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP CMS3_k127_474891_29 1189612.A33Q_0417 2.087e-67 233.0 COG0328@1|root,COG0328@2|Bacteria,4NNQX@976|Bacteroidetes,47PXE@768503|Cytophagia 976|Bacteroidetes L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H CMS3_k127_474891_17 1237149.C900_03771 1.727e-111 370.0 COG1932@1|root,COG1932@2|Bacteria,4PM2C@976|Bacteroidetes,47Y07@768503|Cytophagia 976|Bacteroidetes EH Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine - - 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CMS3_k127_474891_33 1454007.JAUG01000003_gene3080 3.736e-57 202.0 COG0757@1|root,COG0757@2|Bacteria,4NNHU@976|Bacteroidetes,1ISBR@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II CMS3_k127_474891_9 1237149.C900_03773 7.666e-149 476.0 COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,47JU5@768503|Cytophagia 976|Bacteroidetes D Tyrosine recombinase XerC xerC - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase CMS3_k127_474891_35 1317122.ATO12_05710 7.757e-53 194.0 COG5587@1|root,COG5587@2|Bacteria,4NRNM@976|Bacteroidetes,1I8TV@117743|Flavobacteriia,2YIDA@290174|Aquimarina 976|Bacteroidetes S Conserved hypothetical protein (DUF2461) - - - - - - - - - - - - DUF2461 CMS3_k127_474891_1 1121904.ARBP01000006_gene3683 4.585e-239 761.0 COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,47TDS@768503|Cytophagia 976|Bacteroidetes E Phosphotransferase enzyme family - - - - - - - - - - - - APH,Aminotran_3,Peptidase_M23 CMS3_k127_474891_13 269798.CHU_2701 8.38e-125 409.0 COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,47KYQ@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh CMS3_k127_474891_0 1237149.C900_03779 0.0 1086.0 COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,47JI0@768503|Cytophagia 976|Bacteroidetes D DNA segregation ATPase FtsK SpoIIIE ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma CMS3_k127_474891_28 153721.MYP_266 8.825e-68 237.0 COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,47PRT@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane lipoprotein carrier protein LolA lolA - - ko:K03634 - - - - ko00000 - - - LolA,LolA_2 CMS3_k127_474891_15 153721.MYP_268 7.25e-114 372.0 COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,47JHC@768503|Cytophagia 976|Bacteroidetes F Orotidine 5''-phosphate decarboxylase pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase CMS3_k127_474891_19 1237149.C900_03782 1.03e-110 372.0 28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,47KPJ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2851) - - - - - - - - - - - - DUF2851 CMS3_k127_474891_40 1124780.ANNU01000049_gene2176 5.572e-30 133.0 28ICP@1|root,32QUE@2|Bacteria,4NR8Q@976|Bacteroidetes,47QZP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_474891_27 641524.ADICYQ_5168 1.961e-68 238.0 COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,47PJQ@768503|Cytophagia 976|Bacteroidetes S sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family - - - - - - - - - - - - Hexapep CMS3_k127_474891_14 1237149.C900_03785 7.098e-123 399.0 COG2820@1|root,COG2820@2|Bacteria,4NG5S@976|Bacteroidetes,47K9N@768503|Cytophagia 976|Bacteroidetes F PFAM Phosphorylase superfamily udp - 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 - - - PNP_UDP_1 CMS3_k127_474891_31 1356852.N008_14365 1.606e-60 216.0 2BB8B@1|root,324R0@2|Bacteria,4NQG8@976|Bacteroidetes,47RS3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_474891_2 926549.KI421517_gene2571 5.789e-230 722.0 COG1001@1|root,COG1001@2|Bacteria,4NFD9@976|Bacteroidetes,47KX0@768503|Cytophagia 976|Bacteroidetes F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade - 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 CMS3_k127_474891_30 1124780.ANNU01000064_gene435 1.429e-63 225.0 COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,47K5Q@768503|Cytophagia 976|Bacteroidetes F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin CMS3_k127_474891_4 1237149.C900_02255 2.664e-199 631.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,47M23@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrA - 1.6.5.8 ko:K00346 - - - - ko00000,ko01000 - - - NQRA,NQRA_SLBB CMS3_k127_474891_7 1121859.KB890739_gene2256 1.58e-176 560.0 COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,47ND4@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrB - 1.6.5.8 ko:K00347 - - - - ko00000,ko01000 - - - NQR2_RnfD_RnfE CMS3_k127_474891_24 1237149.C900_02251 4.403e-86 291.0 COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,47TVG@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrC - 1.6.5.8 ko:K00348 - - - - ko00000,ko01000 - - - FMN_bind CMS3_k127_474891_16 1237149.C900_02250 1.77e-113 369.0 COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,47P80@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrD - 1.6.5.8 ko:K00349 - - - - ko00000,ko01000 - - - Rnf-Nqr CMS3_k127_474891_21 1237149.C900_02249 6.701e-107 348.0 COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,47KRI@768503|Cytophagia 976|Bacteroidetes C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol nqrE - 1.6.5.8 ko:K00350 - - - - ko00000,ko01000 - - - Rnf-Nqr CMS3_k127_474891_34 1237149.C900_00078 4.547e-54 197.0 COG3571@1|root,COG3571@2|Bacteria,4NEGG@976|Bacteroidetes,47UR6@768503|Cytophagia 976|Bacteroidetes S Dienelactone hydrolase family - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_5 CMS3_k127_474891_10 1121904.ARBP01000011_gene1487 1.579e-142 462.0 COG1387@1|root,COG1387@2|Bacteria,4NHYE@976|Bacteroidetes,47YBS@768503|Cytophagia 976|Bacteroidetes E Histidinol phosphatase and related hydrolases of the PHP family - - - - - - - - - - - - - CMS3_k127_474891_5 1237149.C900_02622 1.666e-188 601.0 COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,47JDY@768503|Cytophagia 976|Bacteroidetes C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bfmBB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS3_k127_474891_11 643867.Ftrac_0526 7.159e-141 458.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia 976|Bacteroidetes S CinA-like protein cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth CMS3_k127_474891_23 1237149.C900_02624 3.59e-87 294.0 2C8XG@1|root,2Z7PK@2|Bacteria,4NEU8@976|Bacteroidetes,47P85@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4197) - - - - - - - - - - - - DUF4197 CMS3_k127_474891_3 1237149.C900_02625 1.622e-215 719.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia 976|Bacteroidetes O Subtilase family - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - PKD,Peptidase_S8 CMS3_k127_4778729_48 760192.Halhy_5034 1.31e-07 54.0 2E5WH@1|root,30K07@2|Bacteria,4P5HE@976|Bacteroidetes 976|Bacteroidetes J 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP CMS3_k127_4778729_0 1046627.BZARG_1517 0.0 1690.0 COG1038@1|root,COG1038@2|Bacteria,4NFHU@976|Bacteroidetes,1HYR4@117743|Flavobacteriia 976|Bacteroidetes C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second cfiB - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA CMS3_k127_4778729_17 1121904.ARBP01000001_gene5830 6.901e-132 446.0 COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_4778729_13 313606.M23134_02050 1.004e-140 469.0 COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_4778729_39 745411.B3C1_18462 3.699e-25 113.0 COG1280@1|root,COG1280@2|Bacteria,1RFU5@1224|Proteobacteria,1S7ES@1236|Gammaproteobacteria,1JAM8@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria E LysE type translocator - - - - - - - - - - - - LysE CMS3_k127_4778729_33 102129.Lepto7375DRAFT_3135 8.442e-48 178.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - 2.3.1.178 ko:K06718 ko00260,ko01100,ko01120,map00260,map01100,map01120 M00033 R06978 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_7 CMS3_k127_4778729_12 471854.Dfer_1184 4.388e-150 488.0 COG1167@1|root,COG1167@2|Bacteria,4NGKQ@976|Bacteroidetes,47NBW@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR CMS3_k127_4778729_37 755732.Fluta_0090 3.726e-27 124.0 COG4743@1|root,COG4743@2|Bacteria,4NU7A@976|Bacteroidetes,1I314@117743|Flavobacteriia,2PB9G@246874|Cryomorphaceae 976|Bacteroidetes S Protein of unknown function (DUF1616) - - - - - - - - - - - - - CMS3_k127_4778729_36 643867.Ftrac_0298 1.675e-30 124.0 COG1695@1|root,COG1695@2|Bacteria,4NQFQ@976|Bacteroidetes 976|Bacteroidetes K PadR family transcriptional regulator - - - - - - - - - - - - PadR CMS3_k127_4778729_10 1048983.EL17_21365 5.437e-180 574.0 COG0486@1|root,COG0486@2|Bacteria,4NECT@976|Bacteroidetes,47JRR@768503|Cytophagia 976|Bacteroidetes S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N CMS3_k127_4778729_7 926549.KI421517_gene3433 1.677e-258 810.0 COG0589@1|root,COG1914@1|root,COG0589@2|Bacteria,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47N3X@768503|Cytophagia 976|Bacteroidetes P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp,Usp CMS3_k127_4778729_21 1048983.EL17_21330 1.115e-85 289.0 COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,47JSQ@768503|Cytophagia 976|Bacteroidetes K Iron dependent repressor, metal binding and dimerisation domain - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA CMS3_k127_4778729_25 1124780.ANNU01000025_gene3417 7.473e-77 271.0 COG0438@1|root,COG0438@2|Bacteria,4NMMT@976|Bacteroidetes,47PDF@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 CMS3_k127_4778729_16 1237149.C900_05814 3.61e-135 434.0 COG2171@1|root,COG2171@2|Bacteria,4NEWD@976|Bacteroidetes,47KHY@768503|Cytophagia 976|Bacteroidetes E Belongs to the transferase hexapeptide repeat family dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 CMS3_k127_4778729_26 1392498.JQLH01000001_gene2177 2.556e-76 263.0 COG1073@1|root,COG1073@2|Bacteria,4NQYV@976|Bacteroidetes,1I37B@117743|Flavobacteriia,2PIT8@252356|Maribacter 976|Bacteroidetes S alpha beta - - - - - - - - - - - - DLH CMS3_k127_4778729_31 1237149.C900_05817 1.096e-56 204.0 COG0457@1|root,COG0457@2|Bacteria,4NN6J@976|Bacteroidetes,47PCR@768503|Cytophagia 976|Bacteroidetes S TPR repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8 CMS3_k127_4778729_15 1313421.JHBV01000035_gene2525 2.702e-137 441.0 COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1IP70@117747|Sphingobacteriia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N CMS3_k127_4778729_38 1237149.C900_02061 6.107e-27 117.0 2DGJ8@1|root,2ZW7H@2|Bacteria,4P7SP@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4778729_11 1237149.C900_05825 3.961e-166 531.0 COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,47KXY@768503|Cytophagia 976|Bacteroidetes I PFAM Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase CMS3_k127_4778729_4 1121012.AUKX01000001_gene1320 4.56e-311 968.0 COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,1HYIK@117743|Flavobacteriia,23HP6@178469|Arenibacter 976|Bacteroidetes M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 CMS3_k127_4778729_45 1048983.EL17_07825 2.816e-10 67.0 2AIV5@1|root,319CC@2|Bacteria,4NRB1@976|Bacteroidetes,47QJ1@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4778729_3 1237149.C900_05827 0.0 1005.0 COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,47JS9@768503|Cytophagia 976|Bacteroidetes L Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CMS3_k127_4778729_1 1237149.C900_05830 0.0 1252.0 COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,47JQZ@768503|Cytophagia 976|Bacteroidetes L Belongs to the type II topoisomerase GyrA ParC subunit family parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_topoisoIV CMS3_k127_4778729_30 203124.Tery_2249 1.328e-60 216.0 COG0566@1|root,COG0566@2|Bacteria,1G05W@1117|Cyanobacteria,1HAR0@1150|Oscillatoriales 1117|Cyanobacteria J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylas_C,SpoU_methylase CMS3_k127_4778729_28 1279009.ADICEAN_02675 2.519e-65 231.0 COG2949@1|root,COG2949@2|Bacteria,4NNQS@976|Bacteroidetes,47MWP@768503|Cytophagia 976|Bacteroidetes S DUF218 domain - - - ko:K03748 - - - - ko00000 - - - DUF218 CMS3_k127_4778729_6 1237149.C900_05833 2.678e-264 840.0 COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia 976|Bacteroidetes M CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_4778729_47 747365.Thena_1304 6.67e-09 67.0 COG0457@1|root,COG0457@2|Bacteria 747365.Thena_1304|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - CMS3_k127_4778729_2 1237149.C900_05835 0.0 1058.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,47MA2@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD CMS3_k127_4778729_23 1279009.ADICEAN_00395 1.507e-82 277.0 COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,47PC6@768503|Cytophagia 976|Bacteroidetes J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N CMS3_k127_4778729_40 1124780.ANNU01000012_gene3916 9.373e-25 104.0 COG0291@1|root,COG0291@2|Bacteria,4NUVR@976|Bacteroidetes,47RYG@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p CMS3_k127_4778729_32 1461577.CCMH01000006_gene1947 6.611e-50 179.0 COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,1I1Z2@117743|Flavobacteriia 976|Bacteroidetes J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 CMS3_k127_4778729_20 1124780.ANNU01000042_gene642 2.499e-104 353.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,47MJ6@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_8 CMS3_k127_4778729_44 1305737.JAFX01000001_gene3004 2.245e-11 74.0 28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,47QT8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4778729_14 1279009.ADICEAN_02472 6.061e-139 452.0 COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,47K95@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_4778729_9 485918.Cpin_7279 2.783e-183 578.0 COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,1IQDJ@117747|Sphingobacteriia 976|Bacteroidetes G AP endonuclease - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N CMS3_k127_4778729_29 926549.KI421517_gene677 1.516e-61 220.0 COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,47NE6@768503|Cytophagia 976|Bacteroidetes G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_4778729_43 313596.RB2501_12022 1.079e-13 81.0 COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 CMS3_k127_4778729_24 1313421.JHBV01000029_gene2007 6.673e-78 268.0 2DBF0@1|root,2Z8VT@2|Bacteria,4NECW@976|Bacteroidetes 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - 1.3.1.22 ko:K12343 ko00140,map00140 - R02208,R02497,R08954,R10242 RC00145 ko00000,ko00001,ko01000 - - - Steroid_dh CMS3_k127_4778729_19 1120968.AUBX01000009_gene377 7.867e-109 370.0 COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,47NWX@768503|Cytophagia 976|Bacteroidetes E GDSL family lipolytic protein - - - - - - - - - - - - Lipase_GDSL CMS3_k127_4778729_5 313606.M23134_06801 6.794e-273 869.0 COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,47Y1Q@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4778729_34 1237149.C900_01186 5.337e-40 151.0 2AGY9@1|root,3176X@2|Bacteria,4NQD4@976|Bacteroidetes,47RA2@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated protein, GldC gldC - - - - - - - - - - - - CMS3_k127_4778729_8 562970.Btus_1007 6.164e-243 766.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4HB5P@91061|Bacilli,278X1@186823|Alicyclobacillaceae 91061|Bacilli I PFAM AMP-dependent synthetase and ligase - - 6.2.1.16 ko:K01907 ko00280,ko00650,map00280,map00650 - R01357 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C CMS3_k127_4778729_18 1279009.ADICEAN_02325 4.263e-120 393.0 COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia 976|Bacteroidetes H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase CMS3_k127_4778729_27 926549.KI421517_gene3848 4.641e-76 260.0 COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,47P98@768503|Cytophagia 976|Bacteroidetes J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C_2,TruB_N CMS3_k127_4778729_22 382464.ABSI01000011_gene2990 1.641e-83 284.0 COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia,2IURU@203494|Verrucomicrobiae 203494|Verrucomicrobiae V Bacitracin resistance protein BacA uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA CMS3_k127_4778729_41 643867.Ftrac_0778 1.168e-20 93.0 2DQ4W@1|root,334SC@2|Bacteria,4NUQX@976|Bacteroidetes,47RZV@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3098) - - - - - - - - - - - - DUF3098 CMS3_k127_4778729_35 1124780.ANNU01000012_gene3938 9.163e-39 148.0 COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,47KM1@768503|Cytophagia 976|Bacteroidetes D Belongs to the ABC-4 integral membrane protein family. FtsX subfamily ftsX GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX CMS3_k127_4799350_4 1237149.C900_04085 1.265e-31 130.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4799350_3 1121904.ARBP01000010_gene2389 1.765e-147 495.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JYF@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4799350_1 1121904.ARBP01000010_gene2393 4.402e-175 576.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JYF@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4799350_2 1121930.AQXG01000008_gene209 8.923e-169 557.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4799350_0 1121904.ARBP01000004_gene960 1.202e-187 597.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_4804937_2 1237149.C900_03963 2.655e-164 529.0 2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47JNN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Caps_assemb_Wzi CMS3_k127_4804937_1 1189612.A33Q_0736 4.552e-228 721.0 COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region msbA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CMS3_k127_4804937_3 1047013.AQSP01000134_gene1348 1.106e-125 437.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4804937_5 1237149.C900_02592 5.097e-37 143.0 COG1695@1|root,COG1695@2|Bacteria,4NV8A@976|Bacteroidetes,47VZE@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_4804937_0 1237149.C900_03967 3.177e-256 798.0 COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,47MUV@768503|Cytophagia 976|Bacteroidetes O magnesium chelatase comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C CMS3_k127_4804937_4 517418.Ctha_0890 3.3e-81 281.0 COG4974@1|root,COG4974@2|Bacteria,1FF1Y@1090|Chlorobi 1090|Chlorobi L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase CMS3_k127_4806491_0 313603.FB2170_08239 6.802e-218 684.0 COG0308@1|root,COG0308@2|Bacteria,4NFTN@976|Bacteroidetes,1HXC0@117743|Flavobacteriia,2PH09@252356|Maribacter 976|Bacteroidetes E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - HEAT_2,Peptidase_M1 CMS3_k127_4828760_29 313603.FB2170_11651 4.347e-10 63.0 COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI8X@252356|Maribacter 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_4828760_1 882083.SacmaDRAFT_1933 2.219e-221 706.0 COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4DYWI@85010|Pseudonocardiales 201174|Actinobacteria C Fe-S oxidoreductase - - - - - - - - - - - - CCG,Fer4_8 CMS3_k127_4828760_14 882083.SacmaDRAFT_1932 1.344e-88 302.0 COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DY2C@85010|Pseudonocardiales 201174|Actinobacteria C Electron transfer flavoprotein alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha,Fer4 CMS3_k127_4828760_19 517418.Ctha_0132 3.887e-47 175.0 COG2086@1|root,COG2086@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K03521 - - - - ko00000 - - iAF987.Gmet_2266 CCG,ETF,Fer4_8 CMS3_k127_4828760_27 517418.Ctha_0132 1.217e-17 84.0 COG2086@1|root,COG2086@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K03521 - - - - ko00000 - - iAF987.Gmet_2266 CCG,ETF,Fer4_8 CMS3_k127_4828760_7 882083.SacmaDRAFT_1930 2.484e-148 477.0 COG2516@1|root,COG2516@2|Bacteria,2H2JZ@201174|Actinobacteria 201174|Actinobacteria S Elongator protein 3, MiaB family, Radical SAM - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM CMS3_k127_4828760_16 517418.Ctha_0128 1.752e-73 263.0 COG0095@1|root,COG0095@2|Bacteria 2|Bacteria H Lipoate-protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,DUF116 CMS3_k127_4828760_12 882083.SacmaDRAFT_1928 4.737e-99 332.0 COG1856@1|root,COG1856@2|Bacteria,2H3RG@201174|Actinobacteria 201174|Actinobacteria S Elongator protein 3, MiaB family, Radical SAM - - - ko:K09711 - - - - ko00000 - - - Radical_SAM CMS3_k127_4828760_24 882083.SacmaDRAFT_1927 4.761e-27 115.0 COG0509@1|root,COG0509@2|Bacteria,2H7M7@201174|Actinobacteria 201174|Actinobacteria E Glycine cleavage H-protein - - - - - - - - - - - - GCV_H CMS3_k127_4828760_4 309801.trd_0150 8.65e-190 600.0 COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi 200795|Chloroflexi C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - CCG CMS3_k127_4828760_18 882083.SacmaDRAFT_1924 7.298e-50 186.0 2DPCA@1|root,331H2@2|Bacteria,2HCYY@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - CMS3_k127_4828760_8 562970.Btus_2496 3.462e-148 476.0 COG1148@1|root,COG1148@2|Bacteria 2|Bacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein hdrA - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_6,Pyr_redox_2 CMS3_k127_4828760_5 562970.Btus_2497 1.45e-181 575.0 COG2048@1|root,COG2048@2|Bacteria,1V67B@1239|Firmicutes 1239|Firmicutes C reductase - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG CMS3_k127_4828760_10 1051632.TPY_3531 1.753e-104 343.0 COG1150@1|root,COG1150@2|Bacteria 2|Bacteria C 4Fe-4S dicluster domain dld - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03390,ko:K18930 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8 CMS3_k127_4828760_20 517418.Ctha_0140 2.578e-43 162.0 COG0509@1|root,COG0509@2|Bacteria 2|Bacteria E glycine decarboxylation via glycine cleavage system gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H CMS3_k127_4828760_25 309801.trd_0158 5.767e-26 111.0 COG2044@1|root,COG2044@2|Bacteria 2|Bacteria - - - - - ko:K07092 - - - - ko00000 - - - DrsE,DrsE_2 CMS3_k127_4828760_17 309801.trd_0142 2.16e-59 219.0 COG0095@1|root,COG0095@2|Bacteria 2|Bacteria H Lipoate-protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C CMS3_k127_4828760_15 331678.Cphamn1_1840 9.552e-74 251.0 COG2210@1|root,COG2210@2|Bacteria,1FE9Q@1090|Chlorobi 1090|Chlorobi S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 CMS3_k127_4828760_26 1382304.JNIL01000001_gene842 3.372e-23 100.0 COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli 91061|Bacilli OP Belongs to the sulfur carrier protein TusA family yrkF - - - - - - - - - - - Rhodanese,TusA CMS3_k127_4828760_28 1313421.JHBV01000003_gene632 5.626e-14 76.0 COG0640@1|root,COG0640@2|Bacteria,4NSQD@976|Bacteroidetes 976|Bacteroidetes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 CMS3_k127_4828760_9 517418.Ctha_0124 2.796e-139 451.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,SPASM CMS3_k127_4828760_2 1122176.KB903565_gene3327 1.984e-210 667.0 COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,4NK7Y@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_11 CMS3_k127_4828760_0 1122176.KB903565_gene3328 0.0 1504.0 COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes 976|Bacteroidetes C Molybdopterin oxidoreductase - - 1.7.2.3,1.8.5.5 ko:K07812,ko:K08352 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.4,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding CMS3_k127_4828760_6 870187.Thini_0272 7.974e-156 510.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - - - - - - - - - - STAS,Sulfate_transp CMS3_k127_4828760_3 1121904.ARBP01000002_gene6937 1.089e-208 660.0 COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,47TKY@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_4828760_13 1461693.ATO10_09273 4.171e-97 340.0 COG0682@1|root,COG0682@2|Bacteria,1R7B3@1224|Proteobacteria 1224|Proteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - - - - - - - - - - LGT,PAP2_3,PEMT CMS3_k127_4828760_23 696748.ASU2_02250 1.34e-33 140.0 2E03A@1|root,32VS4@2|Bacteria,1N4NZ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS3_k127_4828760_11 279714.FuraDRAFT_1495 5.33e-101 344.0 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2VKYW@28216|Betaproteobacteria 28216|Betaproteobacteria P fad dependent oxidoreductase - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 CMS3_k127_4828760_21 756272.Plabr_4030 1.483e-42 160.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family ywlC1 - - - - - - - - - - - DinB_2 CMS3_k127_4843046_9 929703.KE386491_gene799 1.607e-50 182.0 COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_4843046_12 641524.ADICYQ_1883 1.261e-22 102.0 2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,47R28@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4843046_5 1237149.C900_02548 2.647e-131 431.0 COG1570@1|root,COG1570@2|Bacteria,4NE64@976|Bacteroidetes,47NEW@768503|Cytophagia 976|Bacteroidetes L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 CMS3_k127_4843046_14 1168289.AJKI01000056_gene3034 9.902e-13 70.0 COG1722@1|root,COG1722@2|Bacteria,4NXJV@976|Bacteroidetes,2FVH6@200643|Bacteroidia,3XKF5@558415|Marinilabiliaceae 976|Bacteroidetes L Exonuclease VII small subunit xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S CMS3_k127_4843046_1 1124780.ANNU01000005_gene2467 3.987e-248 780.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 CMS3_k127_4843046_0 1237149.C900_02551 3.055e-283 884.0 COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,47KR4@768503|Cytophagia 976|Bacteroidetes L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 CMS3_k127_4843046_11 1237149.C900_02552 7.769e-36 142.0 2ENX1@1|root,33GHZ@2|Bacteria,4NXFU@976|Bacteroidetes,47WQI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4843046_6 1237149.C900_02553 2.619e-108 357.0 COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,47MC7@768503|Cytophagia 976|Bacteroidetes E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS3_k127_4843046_13 641524.ADICYQ_1874 3.074e-22 96.0 2BVK8@1|root,32Y0S@2|Bacteria,4NUUA@976|Bacteroidetes,47RXH@768503|Cytophagia 976|Bacteroidetes S Histone H1-like protein - - - - - - - - - - - - Hc1 CMS3_k127_4843046_3 1237149.C900_04344 5.194e-212 664.0 COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,47KDV@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II - - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_4843046_2 485917.Phep_3289 2.07e-219 690.0 COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,1IPSQ@117747|Sphingobacteriia 976|Bacteroidetes I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase - - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 ko:K01961,ko:K01965,ko:K01968 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00036,M00082,M00373,M00376,M00741 R00742,R01859,R04138,R04385 RC00040,RC00097,RC00253,RC00367,RC00609,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CMS3_k127_4843046_4 1237149.C900_04342 7.737e-189 598.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,47NI5@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 CMS3_k127_4843046_10 1122981.AUME01000010_gene1338 4.173e-49 181.0 COG0424@1|root,COG0424@2|Bacteria,4NNXV@976|Bacteroidetes,2FKYZ@200643|Bacteroidia 976|Bacteroidetes D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf CMS3_k127_4843046_7 153721.MYP_1410 8.809e-102 341.0 COG0859@1|root,COG0859@2|Bacteria,4PKBY@976|Bacteroidetes,47NHC@768503|Cytophagia 976|Bacteroidetes M Glycosyltransferase family 9 (heptosyltransferase) - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 CMS3_k127_4843046_8 1124780.ANNU01000003_gene1400 3.462e-93 313.0 COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,47JF4@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23,OEP CMS3_k127_4856083_9 1237149.C900_03796 7.898e-75 261.0 2BHR8@1|root,32BUM@2|Bacteria,4NR4P@976|Bacteroidetes,47QNP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4856083_4 1237149.C900_03797 9.29e-109 366.0 COG4252@1|root,COG4252@2|Bacteria,4NMM6@976|Bacteroidetes,47PFU@768503|Cytophagia 976|Bacteroidetes T CHASE2 domain - - - - - - - - - - - - CHASE2 CMS3_k127_4856083_2 1185876.BN8_03810 4.06e-116 383.0 COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,47M9T@768503|Cytophagia 976|Bacteroidetes E TIGRFAM LAO AO transport system ATPase argK - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK CMS3_k127_4856083_5 1124780.ANNU01000008_gene2723 8.257e-107 358.0 COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,47MZX@768503|Cytophagia 976|Bacteroidetes P PFAM periplasmic binding protein btuF - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 CMS3_k127_4856083_3 1137281.D778_00399 4.025e-109 362.0 COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,1HXH4@117743|Flavobacteriia 976|Bacteroidetes P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD CMS3_k127_4856083_6 1237149.C900_03811 1.692e-96 328.0 COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes 976|Bacteroidetes HP abc transporter (atp-binding protein) - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran CMS3_k127_4856083_1 1250278.JQNQ01000001_gene1434 4.157e-150 488.0 COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,1HY83@117743|Flavobacteriia 976|Bacteroidetes S PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 CMS3_k127_4856083_0 1121904.ARBP01000006_gene3716 1.093e-241 760.0 COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain yccM_2 - - - - - - - - - - - Fer4,Fer4_5,Fer4_7,Fer4_9 CMS3_k127_4856083_7 1237149.C900_04733 6.123e-91 304.0 COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_4856083_8 1124780.ANNU01000008_gene2736 1.867e-87 304.0 COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,47JDG@768503|Cytophagia 976|Bacteroidetes Q methyltransferase - - - - - - - - - - - - GT87 CMS3_k127_4856083_11 925409.KI911562_gene2749 4.027e-56 202.0 COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,1IXRU@117747|Sphingobacteriia 976|Bacteroidetes S Guanylyl transferase CofC like - - - ko:K09931 - - - - ko00000 - - - DUF2064 CMS3_k127_4856083_12 926549.KI421517_gene2970 3.818e-52 194.0 COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia 976|Bacteroidetes S beta barrel domain - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N CMS3_k127_4856083_10 1124780.ANNU01000033_gene1305 3.13e-70 246.0 COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia 976|Bacteroidetes S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC CMS3_k127_4856083_13 1237149.C900_00532 3.475e-27 116.0 COG2010@1|root,COG2010@2|Bacteria,4NTWV@976|Bacteroidetes,47REP@768503|Cytophagia 976|Bacteroidetes C Cytochrome c, class I aniA - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS3_k127_4856083_16 1237149.C900_05487 1.457e-11 71.0 2EG8H@1|root,33A0B@2|Bacteria,4NY1M@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4856083_15 81824.XP_001747226.1 7.92e-26 125.0 29QRV@1|root,2RX97@2759|Eukaryota,38CMN@33154|Opisthokonta 2759|Eukaryota S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS CMS3_k127_4909212_2 1237149.C900_04950 1.312e-54 200.0 28I8D@1|root,2ZBHJ@2|Bacteria,4NHI9@976|Bacteroidetes,47KUP@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_4909212_0 1237149.C900_04951 3.97e-258 819.0 COG1629@1|root,COG1629@2|Bacteria,4PN6V@976|Bacteroidetes 976|Bacteroidetes P CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4937877_4 1237149.C900_05462 3.484e-128 434.0 COG4251@1|root,COG4251@2|Bacteria,4PM7A@976|Bacteroidetes 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,HATPase_c,HNOBA,HisKA,PAS_3,PAS_9,Response_reg CMS3_k127_4937877_1 1237149.C900_05460 6.304e-193 611.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47NKU@768503|Cytophagia 976|Bacteroidetes T Sigma-54 interaction domain - - - - - - - - - - - - Response_reg,Sigma54_activat CMS3_k127_4937877_8 1237149.C900_05458 3.717e-63 229.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes 976|Bacteroidetes S Transposase - - - - - - - - - - - - - CMS3_k127_4937877_10 1168034.FH5T_18990 4.159e-46 172.0 COG2839@1|root,COG2839@2|Bacteria,4NNIY@976|Bacteroidetes,2FS52@200643|Bacteroidia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score - - - ko:K09793 - - - - ko00000 - - - DUF456 CMS3_k127_4937877_2 1120966.AUBU01000005_gene3780 1.036e-141 464.0 COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 - - - ko00000,ko00001,ko02000 2.A.21,2.A.21.8 - - HD_4,SSF CMS3_k127_4937877_6 1237149.C900_03711 3.669e-120 392.0 COG0121@1|root,COG0121@2|Bacteria 2|Bacteria S cellular modified histidine biosynthetic process egtC - - ko:K18802 - - - - ko00000 - - - GATase_4 CMS3_k127_4937877_7 1121930.AQXG01000009_gene284 6.941e-115 376.0 COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes,1IX2Y@117747|Sphingobacteriia 976|Bacteroidetes I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase CMS3_k127_4937877_0 700598.Niako_5257 2.236e-252 789.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1IRKR@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Bacterial protein of - - - - - - - - - - - - DUF885 CMS3_k127_4937877_11 385682.AFSL01000024_gene2033 2.017e-25 106.0 COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,2G1ET@200643|Bacteroidia,3XKE0@558415|Marinilabiliaceae 976|Bacteroidetes K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CMS3_k127_4937877_3 760192.Halhy_3248 1.061e-134 447.0 COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IV5U@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 CMS3_k127_4937877_9 714943.Mucpa_3255 2.554e-48 182.0 COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1IU82@117747|Sphingobacteriia 976|Bacteroidetes M involved in cell wall biogenesis - - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 CMS3_k127_4937877_5 1296416.JACB01000003_gene720 7.374e-122 396.0 COG3383@1|root,COG3383@2|Bacteria,4PKV4@976|Bacteroidetes,1IKVD@117743|Flavobacteriia,2YKIF@290174|Aquimarina 976|Bacteroidetes C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region hndD - 1.12.1.3,1.17.1.9 ko:K00123,ko:K18332 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 CMS3_k127_4939458_1 1120968.AUBX01000016_gene1839 1.558e-132 425.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia 976|Bacteroidetes C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit bfmBA - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C CMS3_k127_4939458_0 1185876.BN8_00011 5.12e-176 561.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47JGY@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_4939458_2 1121859.KB890756_gene1559 2.911e-61 215.0 COG0245@1|root,COG0245@2|Bacteria,4NP0N@976|Bacteroidetes,47PDR@768503|Cytophagia 976|Bacteroidetes I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB CMS3_k127_4939458_3 1124780.ANNU01000018_gene1633 2.234e-58 210.0 COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,47QBX@768503|Cytophagia 976|Bacteroidetes S S-adenosyl-L-methionine-dependent methyltransferase mnmC - - - - - - - - - - - Methyltransf_30 CMS3_k127_4939458_4 1123037.AUDE01000001_gene1965 6.397e-30 120.0 COG0212@1|root,COG0212@2|Bacteria,4NM97@976|Bacteroidetes,1I19B@117743|Flavobacteriia 976|Bacteroidetes H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family ygfA - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig CMS3_k127_4949635_1 1085623.GNIT_3437 1.208e-171 546.0 COG1680@1|root,COG1680@2|Bacteria,1MXHB@1224|Proteobacteria,1RRUU@1236|Gammaproteobacteria,465ZD@72275|Alteromonadaceae 1236|Gammaproteobacteria V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase CMS3_k127_4949635_0 1237149.C900_01015 1.361e-279 882.0 COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,47M4H@768503|Cytophagia 976|Bacteroidetes S CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_4949757_0 153721.MYP_3046 0.0 1068.0 COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,47JNI@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III alpha subunit - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP CMS3_k127_4949757_2 555500.I215_02073 1.505e-151 488.0 COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,1HXFK@117743|Flavobacteriia 976|Bacteroidetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH CMS3_k127_4949757_4 1237149.C900_04765 4.864e-99 329.0 COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,47P4U@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,Peptidase_S24 CMS3_k127_4949757_5 1250232.JQNJ01000001_gene3161 2.234e-59 219.0 COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,1HX5P@117743|Flavobacteriia 976|Bacteroidetes IQ O-succinylbenzoic acid--CoA ligase menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C CMS3_k127_4949757_3 926549.KI421517_gene3815 2.085e-144 462.0 COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,47JYS@768503|Cytophagia 976|Bacteroidetes H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB - 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_4949757_1 1124780.ANNU01000019_gene1770 9.796e-176 567.0 COG1165@1|root,COG1165@2|Bacteria,4NETZ@976|Bacteroidetes,47JS5@768503|Cytophagia 976|Bacteroidetes H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N CMS3_k127_4949757_6 1279009.ADICEAN_01907 1.97e-45 166.0 COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,47K5Z@768503|Cytophagia 976|Bacteroidetes HQ PFAM chorismate binding enzyme entC - 5.4.4.2 ko:K02361,ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind CMS3_k127_4950177_2 746697.Aeqsu_0858 4.019e-09 66.0 2E9C0@1|root,333JQ@2|Bacteria,4NVAR@976|Bacteroidetes,1I5MD@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4950177_1 1313301.AUGC01000004_gene2230 6.966e-72 260.0 COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 CMS3_k127_4950177_0 504472.Slin_5085 0.0 1293.0 COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia 976|Bacteroidetes P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase CMS3_k127_4950177_3 861299.J421_1863 8.17e-07 62.0 COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria 2|Bacteria K phosphorelay signal transduction system - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - AAA_16,BTAD,TPR_12,Trans_reg_C CMS3_k127_4952227_2 1237149.C900_00387 9.332e-104 344.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_4952227_8 1089545.KB913037_gene5428 1.604e-06 55.0 COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4E225@85010|Pseudonocardiales 201174|Actinobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 CMS3_k127_4952227_0 1121904.ARBP01000006_gene3945 1.052e-232 741.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47JK5@768503|Cytophagia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_4952227_4 1237149.C900_01610 1.719e-67 235.0 COG1331@1|root,COG1331@2|Bacteria,4PKPW@976|Bacteroidetes,47XYJ@768503|Cytophagia 976|Bacteroidetes O Protein of unknown function, DUF255 - - - - - - - - - - - - Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7 CMS3_k127_4952227_5 326442.PSHAa0359 2.737e-38 151.0 2E047@1|root,2ZJQK@2|Bacteria,1RA4Q@1224|Proteobacteria,1S2V2@1236|Gammaproteobacteria,2Q3TY@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_4952227_3 1237149.C900_02704 1.679e-69 243.0 COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes,47XM3@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_4952227_1 1121904.ARBP01000004_gene1125 5.657e-158 514.0 28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated protein GldM gldM - - - - - - - - - - - GldM_C,GldM_N CMS3_k127_5008167_2 1237149.C900_01494 4.568e-121 403.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5008167_6 1249997.JHZW01000003_gene2335 1.104e-20 99.0 COG2318@1|root,COG2318@2|Bacteria,4NRSP@976|Bacteroidetes 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB,DinB_2 CMS3_k127_5008167_0 1121904.ARBP01000004_gene1108 0.0 1042.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5008167_5 1121904.ARBP01000013_gene310 1.172e-61 221.0 COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,47SVW@768503|Cytophagia 976|Bacteroidetes S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS3_k127_5008167_1 388413.ALPR1_11360 7.229e-200 638.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia 976|Bacteroidetes J Amidase - - - - - - - - - - - - Amidase CMS3_k127_5008167_4 742766.HMPREF9455_03730 6.524e-73 260.0 COG1317@1|root,COG1317@2|Bacteria,4NI5I@976|Bacteroidetes,2FMVN@200643|Bacteroidia,22WI5@171551|Porphyromonadaceae 976|Bacteroidetes NU Lipid A 3-O-deacylase (PagL) - - - - - - - - - - - - PagL CMS3_k127_5008167_3 391596.PBAL39_13887 2.637e-111 371.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,1IQPQ@117747|Sphingobacteriia 976|Bacteroidetes G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg CMS3_k127_5016782_0 1121904.ARBP01000004_gene1024 2.68e-208 664.0 COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47JRC@768503|Cytophagia 976|Bacteroidetes S PFAM peptidase S45 penicillin amidase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase CMS3_k127_5016782_3 1237149.C900_03560 3.875e-50 183.0 COG1778@1|root,COG1778@2|Bacteria,4NMHD@976|Bacteroidetes,47QBU@768503|Cytophagia 976|Bacteroidetes S TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family kdsC - 3.1.3.103,3.1.3.45 ko:K03270,ko:K21055 ko00540,ko01100,map00540,map01100 M00063 R03350,R11440 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_3 CMS3_k127_5016782_1 1237149.C900_03561 1.099e-117 385.0 COG2877@1|root,COG2877@2|Bacteria,4NENN@976|Bacteroidetes,47M8B@768503|Cytophagia 976|Bacteroidetes M Belongs to the KdsA family kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 CMS3_k127_5016782_4 1123057.P872_08680 7.151e-34 136.0 COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,47S81@768503|Cytophagia 976|Bacteroidetes K Transcription termination factor nusG - - - - - - - - - - - - NusG CMS3_k127_5016782_2 1519464.HY22_09125 2.772e-52 187.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_20,HTH_5 CMS3_k127_5045046_16 1356852.N008_19600 0.0007327 51.0 2BUWA@1|root,32Q8D@2|Bacteria,4PBQT@976|Bacteroidetes,47WWG@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5045046_2 1121904.ARBP01000004_gene1059 2.193e-158 528.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5045046_1 929556.Solca_2420 9.784e-162 515.0 COG2267@1|root,COG2267@2|Bacteria,4NFIJ@976|Bacteroidetes,1IQBD@117747|Sphingobacteriia 976|Bacteroidetes I Serine aminopeptidase, S33 pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 CMS3_k127_5045046_0 866536.Belba_3185 1.376e-319 995.0 COG1960@1|root,COG1960@2|Bacteria,4NF87@976|Bacteroidetes,47NXN@768503|Cytophagia 976|Bacteroidetes I Acyl-CoA dehydrogenase, middle domain - - 1.3.3.6 ko:K00232 ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146 M00087,M00113 R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_5045046_4 1541065.JRFE01000058_gene5507 1.969e-98 330.0 COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,3VMQS@52604|Pleurocapsales 1117|Cyanobacteria S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 CMS3_k127_5045046_3 714943.Mucpa_2152 1.652e-132 451.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5045046_10 1234664.AMRO01000038_gene3194 3.954e-49 193.0 COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA0E@91061|Bacilli,1WG12@129337|Geobacillus 91061|Bacilli E Saccharopine dehydrogenase C-terminal domain lysDH - 1.4.1.18 ko:K19064 ko00960,ko01100,ko01110,map00960,map01100,map01110 - R00446,R02317 RC00062,RC00694 ko00000,ko00001,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP CMS3_k127_5045046_14 1340493.JNIF01000003_gene4260 7.07e-05 51.0 COG4233@1|root,COG4233@2|Bacteria 2|Bacteria CO Disulphide bond corrector protein DsbC dsbD - 1.8.1.8 ko:K04084,ko:K06888 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 CMS3_k127_5045046_13 1305836.AXVE01000006_gene400 3.173e-18 92.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26EYU@186818|Planococcaceae 91061|Bacilli CO COG0526 Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - AhpC-TSA CMS3_k127_5045046_7 926560.KE387027_gene704 8.265e-80 275.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 CMS3_k127_5045046_6 41431.PCC8801_0005 5.079e-84 286.0 COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece 1117|Cyanobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT CMS3_k127_5045046_5 1123277.KB893174_gene5927 1.06e-89 331.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase,Reg_prop,Y_Y_Y CMS3_k127_5045046_8 1123277.KB893174_gene5928 9.678e-61 218.0 COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_5045046_9 880071.Fleli_2204 2.219e-55 201.0 COG2353@1|root,COG2353@2|Bacteria,4NPGK@976|Bacteroidetes,47XRT@768503|Cytophagia 976|Bacteroidetes S YceI-like domain - - - - - - - - - - - - YceI CMS3_k127_5045046_11 269798.CHU_0282 1.084e-30 133.0 28MS7@1|root,2ZB0M@2|Bacteria,4NHCQ@976|Bacteroidetes,47JQ9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5045046_12 1094466.KQS_08445 3.081e-27 114.0 COG2207@1|root,COG2207@2|Bacteria,4NN9J@976|Bacteroidetes,1I9MT@117743|Flavobacteriia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_5056898_1 504472.Slin_1760 1.445e-104 362.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5056898_3 1223410.KN050846_gene1373 1.199e-44 172.0 COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia 976|Bacteroidetes CO Thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Thioredoxin,Thioredoxin_9 CMS3_k127_5056898_0 1237149.C900_03858 2.118e-193 610.0 COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,47N08@768503|Cytophagia 976|Bacteroidetes EGP Major facilitator superfamily tetA - - ko:K08151 - M00668 - - ko00000,ko00002,ko01504,ko02000 2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75 - - MFS_1,Sugar_tr CMS3_k127_5056898_2 234267.Acid_7015 2.09e-49 185.0 2B47E@1|root,31WYM@2|Bacteria,3Y45I@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - CMS3_k127_5056898_4 1122176.KB903531_gene3057 7.956e-19 93.0 2DQ5N@1|root,334V0@2|Bacteria,4NVQA@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5056898_5 1174504.AJTN02000072_gene4005 3.771e-05 48.0 2EJ6D@1|root,33CXK@2|Bacteria,1UB1Y@1239|Firmicutes,4IMEV@91061|Bacilli,1ZJZP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - CMS3_k127_5091727_2 1197477.IA57_08485 1.806e-13 81.0 COG4783@1|root,COG4783@2|Bacteria,4PPSD@976|Bacteroidetes,1IKSP@117743|Flavobacteriia 976|Bacteroidetes S chaperone-mediated protein folding - - - - - - - - - - - - - CMS3_k127_5091727_0 1121904.ARBP01000009_gene4333 2.543e-35 141.0 COG1595@1|root,COG1595@2|Bacteria,4NTAA@976|Bacteroidetes 976|Bacteroidetes K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - - - - - - - - - - Sigma70_r2 CMS3_k127_5091727_4 1313301.AUGC01000014_gene2453 6.51e-07 59.0 COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes 976|Bacteroidetes M COG NOG06397 non supervised orthologous group - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_5091727_3 203122.Sde_3874 3.222e-09 66.0 arCOG14808@1|root,308PC@2|Bacteria,1RE4D@1224|Proteobacteria,1RTSA@1236|Gammaproteobacteria,46C3V@72275|Alteromonadaceae 1236|Gammaproteobacteria S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 CMS3_k127_5091727_1 700598.Niako_3213 6.446e-20 95.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ0T@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5181794_3 1237149.C900_01083 1.111e-139 454.0 COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,47KMP@768503|Cytophagia 976|Bacteroidetes E PFAM Proline dehydrogenase putA - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh CMS3_k127_5181794_0 1237149.C900_01087 2.721e-295 914.0 COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,47M2W@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DUF4332,tRNA-synt_2,tRNA_anti-codon CMS3_k127_5181794_2 1237149.C900_01088 6.202e-245 782.0 COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,47JIS@768503|Cytophagia 976|Bacteroidetes M Organic solvent tolerance protein OstA - - - - - - - - - - - - - CMS3_k127_5181794_5 1237149.C900_01089 1.46e-100 334.0 COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,47M2P@768503|Cytophagia 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 CMS3_k127_5181794_6 1237149.C900_01090 1.131e-82 285.0 COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,47MMF@768503|Cytophagia 976|Bacteroidetes Q Mammalian cell entry related domain protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD CMS3_k127_5181794_1 1189612.A33Q_3340 3.737e-286 885.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47JYJ@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) accD5 - - - - - - - - - - - Carboxyl_trans CMS3_k127_5181794_4 1124780.ANNU01000030_gene1138 1.897e-121 395.0 COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,47JJ3@768503|Cytophagia 976|Bacteroidetes S Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core2 CMS3_k127_5181794_13 1237149.C900_00245 1.252e-38 151.0 COG0526@1|root,COG0526@2|Bacteria,4NSUU@976|Bacteroidetes,47R9W@768503|Cytophagia 976|Bacteroidetes CO AhpC/TSA family - - - - - - - - - - - - AhpC-TSA,Redoxin CMS3_k127_5181794_12 1124780.ANNU01000030_gene1161 1.694e-42 163.0 COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,47RPQ@768503|Cytophagia 976|Bacteroidetes H Belongs to the P-Pant transferase superfamily sfp - - - - - - - - - - - ACPS CMS3_k127_5181794_7 1237149.C900_00242 2.658e-63 225.0 COG3599@1|root,COG3599@2|Bacteria,4NQDF@976|Bacteroidetes,47QRC@768503|Cytophagia 976|Bacteroidetes D TIGRFAM DivIVA domain divIVA - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA CMS3_k127_5181794_17 1121373.KB903662_gene40 6.731e-15 79.0 COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,47QM5@768503|Cytophagia 976|Bacteroidetes H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB CMS3_k127_5181794_14 1279009.ADICEAN_02765 1.042e-29 120.0 COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,47R1C@768503|Cytophagia 976|Bacteroidetes S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn CMS3_k127_5181794_10 1237149.C900_05758 1.878e-55 198.0 28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,47M02@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5181794_16 1237149.C900_05757 2.618e-27 116.0 COG3339@1|root,COG3339@2|Bacteria,4NVFR@976|Bacteroidetes,47RD8@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 CMS3_k127_5181794_9 1356852.N008_04670 6.062e-56 203.0 COG0702@1|root,COG0702@2|Bacteria,4NG89@976|Bacteroidetes,47PTQ@768503|Cytophagia 976|Bacteroidetes GM epimerase - - - - - - - - - - - - Epimerase,NAD_binding_10 CMS3_k127_5181794_8 1189612.A33Q_1965 3.165e-62 216.0 COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,47P8B@768503|Cytophagia 976|Bacteroidetes J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase CMS3_k127_5181794_11 1235803.C825_01990 6.031e-43 159.0 COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,2FT28@200643|Bacteroidia,22Y6R@171551|Porphyromonadaceae 976|Bacteroidetes S MazG nucleotide pyrophosphohydrolase domain ypjD - - - - - - - - - - - MazG CMS3_k127_5181794_15 1123057.P872_11585 2.128e-27 119.0 COG3358@1|root,COG3358@2|Bacteria,4NFT3@976|Bacteroidetes,47NJY@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 CMS3_k127_5217937_8 1237149.C900_03613 5.889e-52 205.0 COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,4NN56@976|Bacteroidetes,47Q8D@768503|Cytophagia 976|Bacteroidetes M amine dehydrogenase activity - - - - - - - - - - - - CHU_C,VCBS CMS3_k127_5217937_2 1227739.Hsw_1780 6.171e-166 527.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,47KPU@768503|Cytophagia 976|Bacteroidetes G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N CMS3_k127_5217937_5 1237149.C900_05160 2.603e-103 341.0 COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,47JWX@768503|Cytophagia 976|Bacteroidetes K transcriptional regulatory protein - - - - - - - - - - - - Transcrip_reg CMS3_k127_5217937_4 1237149.C900_05161 6.026e-108 357.0 COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,47KBM@768503|Cytophagia 976|Bacteroidetes EG PFAM EamA-like transporter family sam - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA CMS3_k127_5217937_9 313606.M23134_02514 1.3e-51 186.0 COG1225@1|root,COG1225@2|Bacteria,4NQCB@976|Bacteroidetes,47QFU@768503|Cytophagia 976|Bacteroidetes O PFAM AhpC TSA family - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA CMS3_k127_5217937_6 762903.Pedsa_1745 2.745e-92 308.0 COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia 976|Bacteroidetes V Part of the ABC transporter complex LolCDE involved in the translocation of lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran CMS3_k127_5217937_0 153721.MYP_4992 2.396e-206 647.0 COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,47JZU@768503|Cytophagia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA CMS3_k127_5217937_10 1380384.JADN01000007_gene1668 9.446e-42 155.0 COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia 976|Bacteroidetes P Cation efflux family - - - - - - - - - - - - Cation_efflux CMS3_k127_5217937_11 1549858.MC45_10760 5.62e-11 70.0 2DF6E@1|root,32U4S@2|Bacteria,1N20C@1224|Proteobacteria,2UFPS@28211|Alphaproteobacteria,2K424@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - CMS3_k127_5217937_3 1237149.C900_04040 2.334e-143 483.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5217937_1 929703.KE386491_gene540 1.066e-200 647.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47N2K@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_5217937_7 700598.Niako_0548 1.157e-66 231.0 COG2080@1|root,COG2080@2|Bacteria,4NMVV@976|Bacteroidetes,1IXEY@117747|Sphingobacteriia 976|Bacteroidetes C COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_5219756_5 1237149.C900_01204 1.904e-10 65.0 COG4700@1|root,COG4700@2|Bacteria,4PPNH@976|Bacteroidetes,47YQ2@768503|Cytophagia 976|Bacteroidetes T PFAM Protein kinase domain - - - - - - - - - - - - - CMS3_k127_5219756_0 643867.Ftrac_1202 1.319e-200 629.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JS8@768503|Cytophagia 976|Bacteroidetes I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS3_k127_5219756_2 1237149.C900_01202 1.566e-99 343.0 COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PSU@768503|Cytophagia 976|Bacteroidetes S PFAM MORN repeat variant - - - - - - - - - - - - MORN_2 CMS3_k127_5219756_1 1237149.C900_04767 1.606e-135 437.0 COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,47JZR@768503|Cytophagia 976|Bacteroidetes F PFAM SAICAR synthetase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt CMS3_k127_5219756_4 1237149.C900_04768 1.141e-53 192.0 COG1366@1|root,COG1366@2|Bacteria,4NTPB@976|Bacteroidetes,47R1F@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - - - - - - - - - - STAS,STAS_2 CMS3_k127_5219756_3 1237149.C900_04769 7.062e-83 282.0 COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,47KGX@768503|Cytophagia 976|Bacteroidetes S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 CMS3_k127_5244653_1 1237149.C900_01769 2.398e-182 577.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47KFY@768503|Cytophagia 976|Bacteroidetes C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit bfmBA - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C CMS3_k127_5244653_5 1124780.ANNU01000018_gene1639 2.986e-43 162.0 COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes,47QCI@768503|Cytophagia 976|Bacteroidetes O redox protein regulator of disulfide bond formation osmC - - - - - - - - - - - OsmC CMS3_k127_5244653_4 1237149.C900_01773 1.276e-86 292.0 28MPU@1|root,2ZAYW@2|Bacteria,4NRQD@976|Bacteroidetes,47NJK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5244653_2 1121859.KB890738_gene2962 1.538e-164 520.0 COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia 976|Bacteroidetes H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM CMS3_k127_5244653_0 926549.KI421517_gene695 2.189e-235 745.0 COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,47K79@768503|Cytophagia 976|Bacteroidetes G PFAM Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CBM9_1,Glyco_hydro_20,Glyco_hydro_20b,Glycohydro_20b2 CMS3_k127_5244653_3 313606.M23134_01996 4.193e-126 414.0 COG0477@1|root,COG2814@2|Bacteria,4NEZT@976|Bacteroidetes,47M0X@768503|Cytophagia 976|Bacteroidetes EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_5244653_7 1358423.N180_06505 8.504e-27 114.0 COG0789@1|root,COG0789@2|Bacteria,4NRVD@976|Bacteroidetes,1IZTY@117747|Sphingobacteriia 976|Bacteroidetes K MerR, DNA binding - - - - - - - - - - - - MerR_1 CMS3_k127_5244653_8 1358423.N180_06500 1.748e-26 113.0 arCOG13956@1|root,33BWW@2|Bacteria,4P4JQ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5256806_1 1237149.C900_03344 2.724e-116 383.0 COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47K6V@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag,POTRA CMS3_k127_5256806_0 1237149.C900_03343 0.0 1056.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,47JUS@768503|Cytophagia 976|Bacteroidetes C Transketolase, pyrimidine binding domain bfmBAB - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C CMS3_k127_5256806_6 643867.Ftrac_1489 4.288e-52 190.0 COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,47RBP@768503|Cytophagia 976|Bacteroidetes I PFAM PAP2 superfamily ybjG GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 CMS3_k127_5256806_4 1123278.KB893557_gene3833 1.48e-78 266.0 COG0307@1|root,COG0307@2|Bacteria,4NHI8@976|Bacteroidetes,47JY5@768503|Cytophagia 976|Bacteroidetes H TIGRFAM riboflavin synthase, alpha subunit ribE - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding CMS3_k127_5256806_3 1237149.C900_01201 1.171e-91 305.0 COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,47P7V@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT CMS3_k127_5256806_5 1279009.ADICEAN_03480 9.193e-75 256.0 COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,47P9H@768503|Cytophagia 976|Bacteroidetes I PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT CMS3_k127_5256806_2 1408433.JHXV01000048_gene3353 5.475e-95 318.0 COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes 976|Bacteroidetes V ABC transporter - - - - - - - - - - - - ABC_tran CMS3_k127_5256806_7 1408433.JHXV01000048_gene3354 2.794e-24 111.0 COG1668@1|root,COG1668@2|Bacteria 2|Bacteria CP transmembrane transport - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 CMS3_k127_5256806_8 1313421.JHBV01000008_gene4375 4.739e-23 108.0 28KF6@1|root,2ZA1E@2|Bacteria,4NM2F@976|Bacteroidetes 976|Bacteroidetes - - - - - ko:K16905 ko02010,map02010 M00224 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - - CMS3_k127_527871_4 1237149.C900_03167 1.017e-131 427.0 COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia 976|Bacteroidetes S TPR repeat-containing protein - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8 CMS3_k127_527871_14 471854.Dfer_0837 5.608e-39 150.0 COG1708@1|root,COG2250@1|root,COG1708@2|Bacteria,COG2250@2|Bacteria,4NNCW@976|Bacteroidetes,47Q96@768503|Cytophagia 976|Bacteroidetes S HEPN domain - - - - - - - - - - - - HEPN CMS3_k127_527871_15 471854.Dfer_0837 2.013e-21 96.0 COG1708@1|root,COG2250@1|root,COG1708@2|Bacteria,COG2250@2|Bacteria,4NNCW@976|Bacteroidetes,47Q96@768503|Cytophagia 976|Bacteroidetes S HEPN domain - - - - - - - - - - - - HEPN CMS3_k127_527871_13 319795.Dgeo_1745 6.392e-41 152.0 COG2343@1|root,COG2343@2|Bacteria,1WN4Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Domain of unknown function (DUF427) - - - - - - - - - - - - NTP_transf_9 CMS3_k127_527871_8 143224.JQMD01000002_gene3435 7.357e-58 205.0 COG0251@1|root,COG0251@2|Bacteria,4NPF9@976|Bacteroidetes,1I1J9@117743|Flavobacteriia 976|Bacteroidetes J endoribonuclease L-PSP - - - - - - - - - - - - YjgF_endoribonc CMS3_k127_527871_6 1443665.JACA01000049_gene5424 2.902e-86 299.0 COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,1HZQK@117743|Flavobacteriia 976|Bacteroidetes E Succinylglutamate desuccinylase / Aspartoacylase family astE - 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - - AstE_AspA CMS3_k127_527871_2 1121904.ARBP01000001_gene5821 2.902e-197 633.0 COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,47N77@768503|Cytophagia 976|Bacteroidetes S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS,GCS2 CMS3_k127_527871_0 1124780.ANNU01000016_gene1823 3.882e-239 755.0 COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia 976|Bacteroidetes E Leukotriene A4 hydrolase, C-terminal - - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 CMS3_k127_527871_16 1151122.AQYD01000007_gene24 1.413e-17 91.0 COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria,4FS38@85023|Microbacteriaceae 201174|Actinobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.11 ko:K03428 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R04237 RC00003,RC00460 ko00000,ko00001,ko01000 - - - Methyltransf_11,Methyltransf_25 CMS3_k127_527871_11 1123326.JFBL01000023_gene2544 4.934e-48 182.0 COG1741@1|root,COG1741@2|Bacteria 2|Bacteria O Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C CMS3_k127_527871_10 98439.AJLL01000104_gene2980 7.829e-49 181.0 COG0778@1|root,COG0778@2|Bacteria,1G42X@1117|Cyanobacteria,1JITT@1189|Stigonemataceae 1117|Cyanobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase CMS3_k127_527871_12 1191523.MROS_1351 7.896e-43 161.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity slyA - - - - - - - - - - - HTH_27,MarR,MarR_2 CMS3_k127_527871_3 1237149.C900_05563 5.189e-142 460.0 COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes,47M8G@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase CMS3_k127_527871_7 1237149.C900_05564 6.061e-67 233.0 2D9XB@1|root,32TU6@2|Bacteria,4NSXG@976|Bacteroidetes,47R3J@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_527871_5 1237149.C900_05565 4.013e-105 348.0 COG3279@1|root,COG3279@2|Bacteria,4NP0E@976|Bacteroidetes,47Q29@768503|Cytophagia 976|Bacteroidetes KT LytTr DNA-binding domain - - - - - - - - - - - - LytTR CMS3_k127_527871_1 1380600.AUYN01000001_gene2650 1.298e-213 670.0 COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1HXEA@117743|Flavobacteriia 976|Bacteroidetes G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,Fucosidase_C CMS3_k127_5285516_2 1250232.JQNJ01000001_gene1368 2.264e-68 239.0 COG0666@1|root,COG0666@2|Bacteria,4NIQ8@976|Bacteroidetes,1I0V8@117743|Flavobacteriia 976|Bacteroidetes T Protein phosphatase 2A homologues, catalytic domain. - - - - - - - - - - - - Ank_2,Metallophos CMS3_k127_5285516_4 1237149.C900_01969 2.484e-48 183.0 COG3291@1|root,COG3291@2|Bacteria,4NV3K@976|Bacteroidetes,47W7K@768503|Cytophagia 976|Bacteroidetes C Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_5285516_0 760192.Halhy_5529 2.399e-227 715.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IPEX@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_5285516_3 28444.JODQ01000013_gene2933 1.317e-57 206.0 COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria 201174|Actinobacteria S protein conserved in bacteria - - - - - - - - - - - - OmdA CMS3_k127_5285516_5 1223410.KN050846_gene2336 1.588e-44 169.0 COG3527@1|root,COG3527@2|Bacteria,4NKWJ@976|Bacteroidetes,1HX22@117743|Flavobacteriia 976|Bacteroidetes Q Alpha-acetolactate decarboxylase - - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy CMS3_k127_5285516_7 880070.Cycma_4597 7.746e-31 127.0 COG0845@1|root,COG0845@2|Bacteria,4NRKU@976|Bacteroidetes 976|Bacteroidetes M Protein of unknown function (DUF3347) - - - - - - - - - - - - DUF3347 CMS3_k127_5285516_1 1124780.ANNU01000033_gene1309 1.991e-172 559.0 COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,47K97@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HlyD_D23,HlyD_D4 CMS3_k127_529128_1 1047013.AQSP01000135_gene1613 3.027e-14 83.0 COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria 2|Bacteria U TolB amino-terminal domain tolB GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N CMS3_k127_529128_0 1348114.OM33_20780 1.526e-28 126.0 COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria,1S3DH@1236|Gammaproteobacteria,2Q2A2@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 CMS3_k127_5304703_4 1166018.FAES_0158 1.713e-66 237.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5304703_3 929713.NIASO_13410 1.431e-68 238.0 COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,1IT6N@117747|Sphingobacteriia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily fecI - - - - - - - - - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_5304703_6 929713.NIASO_13415 1.844e-18 88.0 2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,1IUG5@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5304703_8 1198114.AciX9_0238 2.154e-11 70.0 2E5Q2@1|root,330EP@2|Bacteria,3Y5RC@57723|Acidobacteria,2JK2G@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - CMS3_k127_5304703_7 517417.Cpar_0705 1.629e-15 86.0 COG5523@1|root,COG5523@2|Bacteria,1FEN5@1090|Chlorobi 1090|Chlorobi S integral membrane protein - - - - - - - - - - - - - CMS3_k127_5304703_9 742767.HMPREF9456_01170 0.0002844 47.0 2BT4K@1|root,32N98@2|Bacteria,4PC3Q@976|Bacteroidetes,2FYER@200643|Bacteroidia 976|Bacteroidetes S Protein of unknown function (DUF2752) - - - - - - - - - - - - DUF2752 CMS3_k127_5304703_5 1237149.C900_02632 4.369e-27 112.0 COG4095@1|root,COG4095@2|Bacteria 2|Bacteria S Sugar efflux transporter for intercellular exchange - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - MtN3_slv,PQ-loop CMS3_k127_5304703_0 1185876.BN8_04332 7e-323 1009.0 COG2866@1|root,COG2866@2|Bacteria,4NF3D@976|Bacteroidetes,47UEQ@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 CMS3_k127_5304703_2 1239962.C943_03769 3.545e-69 248.0 COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia 976|Bacteroidetes I fatty acid desaturase - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS3_k127_5304703_1 1443665.JACA01000014_gene4486 3.817e-77 268.0 2C34F@1|root,2ZA5Y@2|Bacteria,4NGPA@976|Bacteroidetes,1I297@117743|Flavobacteriia,2YJ8N@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5312942_5 143224.JQMD01000002_gene2942 8.029e-64 224.0 COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes,1HXY7@117743|Flavobacteriia 976|Bacteroidetes P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA CMS3_k127_5312942_2 1121904.ARBP01000006_gene3731 1.525e-188 604.0 COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia 976|Bacteroidetes P COGs COG0659 Sulfate permease and related transporter (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - Sulfate_transp CMS3_k127_5312942_0 1121875.KB907549_gene2018 2.147e-211 670.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,1HYSX@117743|Flavobacteriia 976|Bacteroidetes Q COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - - - - - - - - - - Amidohydro_3 CMS3_k127_5312942_11 1122176.KB903534_gene2172 4.054e-36 145.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1ITBV@117747|Sphingobacteriia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_5312942_6 1237149.C900_04058 3.641e-61 215.0 COG2050@1|root,COG2050@2|Bacteria,4P2ZC@976|Bacteroidetes 976|Bacteroidetes Q Domain of unknown function (DUF4442) - - - - - - - - - - - - DUF4442 CMS3_k127_5312942_1 1124780.ANNU01000056_gene3481 2.741e-206 651.0 COG1757@1|root,COG1757@2|Bacteria,4NFQT@976|Bacteroidetes,47KKY@768503|Cytophagia 976|Bacteroidetes C TIGRFAM Na H antiporter NhaC nhaC - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter CMS3_k127_5312942_8 1237149.C900_05499 7.789e-57 203.0 COG0349@1|root,COG0349@2|Bacteria,4NP3B@976|Bacteroidetes,47QFS@768503|Cytophagia 976|Bacteroidetes J 3'-5' exonuclease rnd - - - - - - - - - - - DNA_pol_A_exo1 CMS3_k127_5312942_7 1237149.C900_05498 3.327e-60 214.0 COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,47P9D@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised protein family UPF0029, Impact, N-terminal yigZ - - - - - - - - - - - UPF0029 CMS3_k127_5312942_9 1124780.ANNU01000056_gene3485 3.414e-56 207.0 COG0697@1|root,COG0697@2|Bacteria,4NGWA@976|Bacteroidetes,47K3C@768503|Cytophagia 976|Bacteroidetes EG Transporter - - - - - - - - - - - - EamA CMS3_k127_5312942_10 1237149.C900_04061 2.576e-43 169.0 COG5653@1|root,COG5653@2|Bacteria,4NKJS@976|Bacteroidetes,47NWT@768503|Cytophagia 976|Bacteroidetes M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6,FemAB CMS3_k127_5312942_4 1237149.C900_04066 3.649e-74 259.0 COG1216@1|root,COG1216@2|Bacteria,4NJQR@976|Bacteroidetes,47MWK@768503|Cytophagia 976|Bacteroidetes S PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_5312942_3 1237149.C900_03736 2.553e-107 355.0 COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,47JC5@768503|Cytophagia 976|Bacteroidetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N CMS3_k127_5386830_0 1237149.C900_04596 4.346e-220 708.0 COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,47K0V@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeats sprE - - - - - - - - - - - TPR_16,TPR_6,TPR_8 CMS3_k127_5386830_1 643867.Ftrac_2561 2.21e-104 348.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47K6R@768503|Cytophagia 976|Bacteroidetes M Penicillin binding protein transpeptidase pbpB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS3_k127_5417764_1 1237149.C900_02472 4.711e-145 466.0 COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MXD@768503|Cytophagia 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH CMS3_k127_5417764_0 1237149.C900_02470 2.464e-254 797.0 COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47KHA@768503|Cytophagia 976|Bacteroidetes S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CMS3_k127_5440288_1 1124780.ANNU01000045_gene2285 4.214e-257 797.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,47JB3@768503|Cytophagia 976|Bacteroidetes J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind CMS3_k127_5440288_0 1124780.ANNU01000045_gene2283 6.519e-311 961.0 COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,47KWA@768503|Cytophagia 976|Bacteroidetes T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 CMS3_k127_5440288_5 1237149.C900_03830 2.654e-116 383.0 COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47T9B@768503|Cytophagia 976|Bacteroidetes Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD CMS3_k127_5440288_4 1237149.C900_03831 8.856e-123 397.0 COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,47NIJ@768503|Cytophagia 976|Bacteroidetes Q ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran CMS3_k127_5440288_2 1237149.C900_03832 1.023e-135 435.0 COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,47K33@768503|Cytophagia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents permease component - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE CMS3_k127_5440288_7 323098.Nwi_0207 4.547e-33 138.0 COG2242@1|root,COG2242@2|Bacteria,1QW6F@1224|Proteobacteria,2TWPP@28211|Alphaproteobacteria,3JV9N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Methyltransf_21 CMS3_k127_5440288_3 1237149.C900_02611 4.258e-132 426.0 COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,47JX5@768503|Cytophagia 976|Bacteroidetes IQ Short-chain dehydrogenase reductase SDR ykuF - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 CMS3_k127_5440288_6 1237149.C900_02612 1.153e-92 313.0 COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,47NTZ@768503|Cytophagia 976|Bacteroidetes N OmpA family - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA CMS3_k127_5466737_2 743722.Sph21_2793 2.265e-11 64.0 COG3832@1|root,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity yndB - - - - - - - - - - - AHSA1 CMS3_k127_5466737_0 743722.Sph21_2794 6.663e-34 134.0 COG0640@1|root,COG0640@2|Bacteria,4NTCN@976|Bacteroidetes,1IYA0@117747|Sphingobacteriia 976|Bacteroidetes K regulatory protein, arsR - - - - - - - - - - - - HTH_20,HTH_5 CMS3_k127_5469220_6 1237149.C900_02472 1.978e-39 148.0 COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47MXD@768503|Cytophagia 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH CMS3_k127_5469220_4 1121930.AQXG01000002_gene2258 1.311e-55 199.0 COG0457@1|root,COG0457@2|Bacteria,4NNWA@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_5469220_1 1121904.ARBP01000002_gene6750 1.118e-273 856.0 COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia 976|Bacteroidetes I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE CMS3_k127_5469220_7 1279009.ADICEAN_04149 7.823e-20 91.0 2EGC0@1|root,33A3T@2|Bacteria,4NXPB@976|Bacteroidetes,47SUC@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5469220_5 485918.Cpin_1946 1.296e-47 172.0 COG2315@1|root,COG2315@2|Bacteria,4NS6J@976|Bacteroidetes,1IT89@117747|Sphingobacteriia 976|Bacteroidetes S YjbR - - - - - - - - - - - - YjbR CMS3_k127_5469220_0 926549.KI421517_gene3703 0.0 1139.0 COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,47MI0@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2 CMS3_k127_5469220_2 1250005.PHEL85_2981 4.844e-81 282.0 COG3386@1|root,COG3386@2|Bacteria,4NNEW@976|Bacteroidetes,1I8HS@117743|Flavobacteriia,3VX0I@52959|Polaribacter 976|Bacteroidetes G Arylesterase - - - - - - - - - - - - Arylesterase CMS3_k127_5469220_3 1124780.ANNU01000036_gene34 4.633e-64 223.0 COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,47M9P@768503|Cytophagia 976|Bacteroidetes E Amino acid permease - - - - - - - - - - - - AA_permease CMS3_k127_548114_11 929562.Emtol_0570 5.015e-37 141.0 COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,47M2Z@768503|Cytophagia 976|Bacteroidetes M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 CMS3_k127_548114_0 1237149.C900_02212 2.935e-179 572.0 COG1030@1|root,COG1030@2|Bacteria,4NGGV@976|Bacteroidetes,47MQR@768503|Cytophagia 976|Bacteroidetes O Membrane-bound serine protease (ClpP class) - - - ko:K07403 - - - - ko00000 - - - NfeD,Peptidase_S49,SDH_sah CMS3_k127_548114_5 1237149.C900_02210 8.355e-82 284.0 COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,47NR5@768503|Cytophagia 976|Bacteroidetes M PFAM LysM domain lysM - - - - - - - - - - - ANF_receptor,LysM,Peripla_BP_6 CMS3_k127_548114_3 1124780.ANNU01000024_gene3076 4.787e-108 356.0 COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,47K0Q@768503|Cytophagia 976|Bacteroidetes L TIGRFAM TIGR02757 family protein - - - - - - - - - - - - DUF2400 CMS3_k127_548114_4 1237149.C900_02208 5.991e-86 289.0 COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,47JX7@768503|Cytophagia 976|Bacteroidetes F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10,4.1.1.23 ko:K00762,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase,Pribosyltran CMS3_k127_548114_8 1123057.P872_18135 1.102e-52 194.0 COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,47NQ9@768503|Cytophagia 976|Bacteroidetes F NUDIX domain - - - - - - - - - - - - NUDIX CMS3_k127_548114_6 1288963.ADIS_3419 5.325e-67 231.0 COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,47PE3@768503|Cytophagia 976|Bacteroidetes H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CMS3_k127_548114_2 1237149.C900_02205 2.741e-109 361.0 29SSC@1|root,30DYA@2|Bacteria,4NM51@976|Bacteroidetes,47PSA@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3822) - - - - - - - - - - - - DUF3822 CMS3_k127_548114_9 643867.Ftrac_0892 7.963e-50 183.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,47NP8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_548114_10 1166018.FAES_2827 2.563e-40 156.0 COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia 976|Bacteroidetes F Nudix hydrolase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX CMS3_k127_548114_7 1237149.C900_02202 4.228e-54 193.0 COG2050@1|root,COG2050@2|Bacteria,4NT7R@976|Bacteroidetes,47RY0@768503|Cytophagia 976|Bacteroidetes Q Thioesterase superfamily - - - - - - - - - - - - 4HBT CMS3_k127_548114_1 643867.Ftrac_0889 4.338e-176 563.0 COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,47MBF@768503|Cytophagia 976|Bacteroidetes L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member recD2_2 - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 CMS3_k127_5522781_0 1125863.JAFN01000001_gene2540 1.681e-78 277.0 2DN8B@1|root,32W2U@2|Bacteria,1R03I@1224|Proteobacteria,42XCH@68525|delta/epsilon subdivisions,2WT8A@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_5522781_3 224325.AF_1627 1.436e-20 92.0 COG1476@1|root,arCOG01864@2157|Archaea,2Y089@28890|Euryarchaeota 28890|Euryarchaeota K Transcriptional regulator - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 CMS3_k127_5522781_1 1430440.MGMSRv2_0733 2.438e-51 203.0 COG2114@1|root,COG2114@2|Bacteria,1R86S@1224|Proteobacteria,2U57P@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - DUF4071,Guanylate_cyc CMS3_k127_5522781_2 388413.ALPR1_05535 1.355e-38 155.0 COG1566@1|root,COG1566@2|Bacteria,4NVBT@976|Bacteroidetes,47VR7@768503|Cytophagia 976|Bacteroidetes V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 CMS3_k127_5599149_2 1121904.ARBP01000004_gene767 2.102e-84 284.0 COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,47NCP@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3109) - - - - - - - - - - - - DUF3109 CMS3_k127_5599149_1 929556.Solca_2890 2.971e-184 586.0 COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes,1IQJT@117747|Sphingobacteriia 976|Bacteroidetes V Mate efflux family protein - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE CMS3_k127_5599149_3 1237149.C900_00281 5.324e-50 199.0 COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes,47MD8@768503|Cytophagia 976|Bacteroidetes K Tetratricopeptide repeat - - - - - - - - - - - - TPR_12,TPR_8 CMS3_k127_5599149_0 1237149.C900_00628 6.045e-235 730.0 COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia 976|Bacteroidetes I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CMS3_k127_5605096_16 880071.Fleli_0867 3.462e-11 76.0 COG0457@1|root,COG0457@2|Bacteria,4PP7B@976|Bacteroidetes,47WME@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_5605096_9 861299.J421_2137 3.45e-81 294.0 COG4733@1|root,COG4733@2|Bacteria 2|Bacteria S cellulase activity - - - - - - - - - - - - DUF2961 CMS3_k127_5605096_14 1144275.COCOR_01142 3.19e-13 83.0 COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria,2YTXM@29|Myxococcales 28221|Deltaproteobacteria E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,TPR_16,TPR_19,TPR_8,Transglut_core CMS3_k127_5605096_10 1042377.AFPJ01000051_gene33 5.84e-69 244.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B CMS3_k127_5605096_0 1120966.AUBU01000005_gene3809 0.0 1408.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes 976|Bacteroidetes T PFAM BNR Asp-box repeat - - - - - - - - - - - - BNR_6,Sortilin-Vps10 CMS3_k127_5605096_5 865937.Gilli_0101 1.107e-138 446.0 COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1HY4C@117743|Flavobacteriia,2P6G4@244698|Gillisia 976|Bacteroidetes P Dimerisation domain of Zinc Transporter fieF - - - - - - - - - - - Cation_efflux,ZT_dimer CMS3_k127_5605096_2 643867.Ftrac_0656 1.737e-244 762.0 COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,47JPR@768503|Cytophagia 976|Bacteroidetes E PFAM Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 CMS3_k127_5605096_3 1237149.C900_01007 1.325e-213 681.0 COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - CarbopepD_reg_2,DUF3520,VWA,vWF_A CMS3_k127_5605096_11 1237149.C900_01006 6.832e-51 186.0 COG1595@1|root,COG1595@2|Bacteria,4NNEM@976|Bacteroidetes,47P9F@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5605096_17 1279009.ADICEAN_02556 3.863e-05 55.0 COG0810@1|root,COG0810@2|Bacteria,4NSYT@976|Bacteroidetes,47S8R@768503|Cytophagia 976|Bacteroidetes M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - CarbopepD_reg_2,TonB_C CMS3_k127_5605096_15 1239962.C943_04007 8.747e-12 77.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,47KAX@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_5605096_13 714943.Mucpa_2505 1.709e-19 96.0 2A7Q4@1|root,30WNS@2|Bacteria,4PA1Z@976|Bacteroidetes,1ITZ9@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5605096_4 927658.AJUM01000037_gene2270 1.523e-143 470.0 COG1502@1|root,COG1502@2|Bacteria,4NE2W@976|Bacteroidetes,2FMEA@200643|Bacteroidia,3XIXQ@558415|Marinilabiliaceae 976|Bacteroidetes I Phospholipase_D-nuclease N-terminal cls - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N CMS3_k127_5605096_12 666686.B1NLA3E_10450 9.207e-32 125.0 COG3708@1|root,COG3708@2|Bacteria,1VJT1@1239|Firmicutes,4HREN@91061|Bacilli,1ZRAV@1386|Bacillus 91061|Bacilli K Putative zinc ribbon domain - - - - - - - - - - - - Zn_ribbon_2 CMS3_k127_5605096_8 1237149.C900_04415 4.163e-85 295.0 COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes,47R1H@768503|Cytophagia 976|Bacteroidetes V Protein of unknown function (DUF3667) - - - - - - - - - - - - DUF3667 CMS3_k127_5605096_6 1237149.C900_04417 3.374e-120 407.0 COG0683@1|root,COG0683@2|Bacteria,4PKN8@976|Bacteroidetes,47NJW@768503|Cytophagia 976|Bacteroidetes E PFAM Receptor family ligand binding region - - - - - - - - - - - - Peripla_BP_6 CMS3_k127_5605096_1 1120968.AUBX01000009_gene101 3.187e-256 797.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia 976|Bacteroidetes F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase CMS3_k127_5605096_7 1237149.C900_01588 8.408e-99 338.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - 3.4.11.2,3.4.24.3 ko:K01256,ko:K01387 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002,ko02042 - - - HEAT_2,HEAT_PBS,Peptidase_M1,Peptidase_M9,Peptidase_M9_N CMS3_k127_5618595_7 1123277.KB893187_gene2725 3.105e-39 154.0 COG1983@1|root,COG1983@2|Bacteria,4NS0M@976|Bacteroidetes,47QMV@768503|Cytophagia 976|Bacteroidetes KT Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_5618595_2 1313301.AUGC01000005_gene215 1.582e-137 461.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NJB2@976|Bacteroidetes 976|Bacteroidetes MU OmpA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_5618595_0 1313301.AUGC01000012_gene1384 0.0 1190.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes 976|Bacteroidetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN CMS3_k127_5618595_8 643867.Ftrac_2729 3.412e-35 139.0 COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,47QPE@768503|Cytophagia 976|Bacteroidetes K TIGRFAM Rrf2 family protein - - - - - - - - - - - - Rrf2 CMS3_k127_5618595_6 1380600.AUYN01000007_gene3383 1.735e-45 170.0 COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia 976|Bacteroidetes M COG2335 Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - Fasciclin CMS3_k127_5618595_5 153721.MYP_4660 8.371e-60 215.0 COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia 976|Bacteroidetes S DUF218 domain - - - - - - - - - - - - DUF218 CMS3_k127_5618595_1 945713.IALB_2618 2.357e-183 584.0 COG3033@1|root,COG3033@2|Bacteria 2|Bacteria E tryptophanase activity tnaA - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase CMS3_k127_5618595_4 1120965.AUBV01000011_gene1516 3.405e-126 413.0 COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes 976|Bacteroidetes E renal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 CMS3_k127_5618595_3 1123234.AUKI01000020_gene814 7.06e-129 418.0 COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1HYEZ@117743|Flavobacteriia 976|Bacteroidetes H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA CMS3_k127_5621784_1 1392489.JPOL01000002_gene363 9.045e-34 132.0 COG3934@1|root,COG3934@2|Bacteria,4NFVS@976|Bacteroidetes,1HZVW@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase CMS3_k127_5621784_0 1191523.MROS_0969 2.766e-269 845.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CMS3_k127_5661090_5 63737.Npun_R2384 1.061e-14 77.0 COG0454@1|root,COG0456@2|Bacteria,1G8AX@1117|Cyanobacteria,1HSKK@1161|Nostocales 1117|Cyanobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_5661090_1 700598.Niako_1535 1.433e-67 236.0 28K10@1|root,2Z9QW@2|Bacteria,4NF8J@976|Bacteroidetes,1ISKT@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4918) - - - - - - - - - - - - DUF4918 CMS3_k127_5661090_4 1280950.HJO_17244 1.393e-27 119.0 COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,2UGMI@28211|Alphaproteobacteria,43Y8Q@69657|Hyphomonadaceae 28211|Alphaproteobacteria G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 CMS3_k127_5661090_3 313606.M23134_02443 5.274e-39 155.0 28J3Q@1|root,2Z8ZW@2|Bacteria,4NGJW@976|Bacteroidetes,47RK7@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (Porph_ging) - - - - - - - - - - - - Porph_ging CMS3_k127_5661090_0 313606.M23134_02442 4.224e-204 666.0 COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 CMS3_k127_5661090_2 1121904.ARBP01000013_gene459 2.461e-67 234.0 28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5661090_6 880073.Calab_2443 5.319e-12 68.0 COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria 2|Bacteria C PFAM Alcohol dehydrogenase, zinc-binding - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N CMS3_k127_5676190_0 1237149.C900_01252 5.404e-167 531.0 COG2812@1|root,COG2812@2|Bacteria,4NE8A@976|Bacteroidetes,47KSQ@768503|Cytophagia 976|Bacteroidetes L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 CMS3_k127_5676190_3 1237149.C900_01251 5.39e-19 94.0 COG3170@1|root,COG3170@2|Bacteria,4PNNG@976|Bacteroidetes,47SUJ@768503|Cytophagia 976|Bacteroidetes NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - CMS3_k127_5676190_1 1237149.C900_03791 1.654e-59 208.0 COG2199@1|root,COG3706@2|Bacteria,4PKDN@976|Bacteroidetes,47QRP@768503|Cytophagia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_5676190_2 1237149.C900_03789 4.988e-32 136.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS3_k127_5691556_0 431943.CKL_1247 5.595e-58 224.0 COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,36USB@31979|Clostridiaceae 186801|Clostridia T metal-dependent phosphohydrolase, HD sub domain - - - - - - - - - - - - GGDEF,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9 CMS3_k127_5691556_1 1379698.RBG1_1C00001G0520 2.891e-52 207.0 COG2208@1|root,COG2208@2|Bacteria 2|Bacteria T phosphoserine phosphatase activity rsbU - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE CMS3_k127_5705305_24 760192.Halhy_6365 3.405e-25 108.0 COG0822@1|root,COG0822@2|Bacteria,4P667@976|Bacteroidetes 976|Bacteroidetes C NifU-like N terminal domain - - - ko:K04488 - - - - ko00000 - - - NifU_N CMS3_k127_5705305_9 313606.M23134_05195 1.216e-103 347.0 COG4447@1|root,COG4447@2|Bacteria,4NKUX@976|Bacteroidetes,47U4I@768503|Cytophagia 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - - CMS3_k127_5705305_27 1121904.ARBP01000006_gene3726 1.226e-21 97.0 COG1977@1|root,COG1977@2|Bacteria,4NVP9@976|Bacteroidetes,47VNX@768503|Cytophagia 976|Bacteroidetes H ThiS family - - - - - - - - - - - - ThiS CMS3_k127_5705305_11 760192.Halhy_5630 1.242e-90 309.0 COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia 976|Bacteroidetes O COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family xdhC - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI CMS3_k127_5705305_15 945713.IALB_2604 1.29e-66 238.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - - - - - - - - - - EamA CMS3_k127_5705305_23 929704.Myrod_3259 4.047e-27 117.0 COG0668@1|root,COG0668@2|Bacteria,4NMMB@976|Bacteroidetes,1I2BV@117743|Flavobacteriia,47I9Y@76831|Myroides 976|Bacteroidetes M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel CMS3_k127_5705305_18 1237149.C900_03852 3.016e-51 187.0 COG1595@1|root,COG1595@2|Bacteria,4NNP4@976|Bacteroidetes,47P6Z@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5705305_14 1304885.AUEY01000004_gene947 9.406e-80 273.0 COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,2MNBG@213118|Desulfobacterales 28221|Deltaproteobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39,Peptidase_C39_2 CMS3_k127_5705305_3 1237149.C900_03854 2.461e-183 585.0 COG0189@1|root,COG0189@2|Bacteria,4NF2R@976|Bacteroidetes,47P1C@768503|Cytophagia 976|Bacteroidetes HJ RimK-like ATPgrasp N-terminal domain - - - - - - - - - - - - Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK CMS3_k127_5705305_4 1237149.C900_03855 1.407e-153 495.0 COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes 976|Bacteroidetes S Glutamate-cysteine ligase family 2(GCS2) - - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 CMS3_k127_5705305_17 1124780.ANNU01000002_gene1605 6.891e-53 194.0 COG3931@1|root,COG3931@2|Bacteria,4NMA3@976|Bacteroidetes,47UX9@768503|Cytophagia 976|Bacteroidetes E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase CMS3_k127_5705305_20 1237149.C900_04900 1.46e-45 168.0 COG4067@1|root,COG4067@2|Bacteria,4NS86@976|Bacteroidetes,47RH0@768503|Cytophagia 976|Bacteroidetes O Putative ATP-dependant zinc protease - - - - - - - - - - - - Zn_protease CMS3_k127_5705305_5 1121904.ARBP01000002_gene7255 6.671e-143 458.0 COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,47KJX@768503|Cytophagia 976|Bacteroidetes HJ Belongs to the RimK family rimK - - ko:K05844 - - - - ko00000,ko01000,ko03009 - - - RimK CMS3_k127_5705305_6 1121904.ARBP01000002_gene7256 8.799e-124 403.0 COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,47KAM@768503|Cytophagia 976|Bacteroidetes S PFAM Succinylglutamate desuccinylase Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA CMS3_k127_5705305_19 1356852.N008_02985 3.008e-50 186.0 COG2095@1|root,COG2095@2|Bacteria,4NIHF@976|Bacteroidetes,47PQ0@768503|Cytophagia 976|Bacteroidetes U MarC family integral membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC CMS3_k127_5705305_16 1120968.AUBX01000012_gene2790 4.432e-53 192.0 COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,47PH5@768503|Cytophagia 976|Bacteroidetes K RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5705305_22 1168034.FH5T_07755 2.758e-34 145.0 COG3712@1|root,COG3712@2|Bacteria,4NICU@976|Bacteroidetes,2FPP5@200643|Bacteroidia 976|Bacteroidetes PT Sigma factor regulatory protein, FecR PupR family - - - - - - - - - - - - DUF4974,FecR CMS3_k127_5705305_7 388413.ALPR1_20173 8.249e-110 378.0 COG4796@1|root,COG4796@2|Bacteria,4PM2P@976|Bacteroidetes,47Y0K@768503|Cytophagia 976|Bacteroidetes U Type ii and iii secretion system protein - - - - - - - - - - - - CarbopepD_reg_2,DUF4974,STN CMS3_k127_5705305_1 1120968.AUBX01000012_gene2797 1.757e-277 873.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec CMS3_k127_5705305_29 929562.Emtol_3130 9.386e-07 59.0 2E16F@1|root,32WM9@2|Bacteria,4NU22@976|Bacteroidetes,47RBV@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5705305_2 760192.Halhy_0186 2.088e-186 594.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia 976|Bacteroidetes O COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 CMS3_k127_5705305_10 1124780.ANNU01000010_gene3656 1.257e-98 333.0 COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47KNA@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - HlyD_D23 CMS3_k127_5705305_0 1237149.C900_01424 0.0 1346.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family bepE_4 - - ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2 - - ACR_tran CMS3_k127_5705305_13 929556.Solca_3159 7.464e-86 304.0 COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1INTW@117747|Sphingobacteriia 976|Bacteroidetes MU PFAM Outer membrane efflux protein tolC - - - - - - - - - - - OEP CMS3_k127_5705305_8 237368.SCABRO_01436 8.566e-107 361.0 COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria 2|Bacteria K 2 iron, 2 sulfur cluster binding yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CMS3_k127_5705305_12 1237149.C900_02850 5.579e-89 298.0 COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes,47NPE@768503|Cytophagia 976|Bacteroidetes F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC CMS3_k127_5705305_26 1279009.ADICEAN_02532 2.879e-22 98.0 COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,47RW5@768503|Cytophagia 976|Bacteroidetes C Acylphosphatase acyP - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase CMS3_k127_5705305_21 1237149.C900_02852 4.351e-38 149.0 2E0QA@1|root,32W90@2|Bacteria,4NUC6@976|Bacteroidetes,47RSZ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5705305_25 313606.M23134_04794 2.831e-23 101.0 COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec CMS3_k127_5718630_5 502025.Hoch_1375 2.508e-19 100.0 COG2304@1|root,COG2304@2|Bacteria,1PDQV@1224|Proteobacteria,43CYI@68525|delta/epsilon subdivisions,2X86P@28221|Deltaproteobacteria 28221|Deltaproteobacteria M SMART Integrin alpha beta-propellor repeat protein - - - - - - - - - - - - FG-GAP_2 CMS3_k127_5718630_3 1237149.C900_01175 1.594e-45 170.0 COG1943@1|root,COG1943@2|Bacteria,4NPUC@976|Bacteroidetes,47Q09@768503|Cytophagia 976|Bacteroidetes L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp CMS3_k127_5718630_2 1123057.P872_06435 4.546e-123 403.0 COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,47K3D@768503|Cytophagia 976|Bacteroidetes I PFAM NAD-dependent glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N CMS3_k127_5718630_1 1237149.C900_00644 1.564e-228 721.0 COG2937@1|root,COG2937@2|Bacteria,4NK5H@976|Bacteroidetes,47M20@768503|Cytophagia 976|Bacteroidetes I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CMS3_k127_5718630_0 641524.ADICYQ_0601 1.106e-259 829.0 COG3291@1|root,COG3291@2|Bacteria,4NFCW@976|Bacteroidetes,47KMB@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C CMS3_k127_5718630_4 1121373.KB903643_gene3447 4.438e-37 142.0 COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,47R74@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 CMS3_k127_5727605_6 1237149.C900_04422 2.942e-65 229.0 28KMN@1|root,2ZA61@2|Bacteria,4NJ9P@976|Bacteroidetes,47P0N@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4062 CMS3_k127_5727605_1 1237149.C900_04421 9.75e-314 993.0 COG1413@1|root,COG1413@2|Bacteria,4PKPI@976|Bacteroidetes,47NQS@768503|Cytophagia 976|Bacteroidetes C - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - HEAT_2,cNMP_binding CMS3_k127_5727605_4 643867.Ftrac_0701 3.061e-110 363.0 COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,47PIS@768503|Cytophagia 976|Bacteroidetes M Small-conductance mechanosensitive channel - - - - - - - - - - - - MS_channel CMS3_k127_5727605_2 1121904.ARBP01000001_gene5843 5.138e-118 392.0 COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,47KMT@768503|Cytophagia 976|Bacteroidetes J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth CMS3_k127_5727605_3 1124780.ANNU01000002_gene1578 1.228e-110 369.0 COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47KCD@768503|Cytophagia 976|Bacteroidetes M PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain menC - - - - - - - - - - - MR_MLE_C CMS3_k127_5727605_5 1239962.C943_01692 1.38e-89 300.0 COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,47KMH@768503|Cytophagia 976|Bacteroidetes K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 CMS3_k127_5727605_0 1237149.C900_01570 0.0 1054.0 COG0550@1|root,COG0550@2|Bacteria,4NF9S@976|Bacteroidetes,47K7C@768503|Cytophagia 976|Bacteroidetes L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt CMS3_k127_5727605_7 1237149.C900_01569 3.949e-41 157.0 COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia 976|Bacteroidetes T PFAM Phosphoglycerate mutase sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 CMS3_k127_5727605_8 1237149.C900_01568 2.923e-26 109.0 COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia 976|Bacteroidetes E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase CMS3_k127_5730398_1 1237149.C900_04790 7.87e-176 554.0 COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,47K8G@768503|Cytophagia 976|Bacteroidetes E Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N CMS3_k127_5730398_25 1046627.BZARG_2537 1.059e-40 155.0 COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia 976|Bacteroidetes V Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal - - - - - - - - - - - - HSDR_N_2 CMS3_k127_5730398_8 1237149.C900_04792 1.497e-132 426.0 COG2820@1|root,COG2820@2|Bacteria,4NESQ@976|Bacteroidetes,47JV3@768503|Cytophagia 976|Bacteroidetes F TIGRFAM AMP nucleosidase amn - 3.2.2.4 ko:K01241 ko00230,map00230 - R00182 RC00063,RC00318 ko00000,ko00001,ko01000 - - - PNP_UDP_1 CMS3_k127_5730398_5 648996.Theam_0664 1.206e-142 472.0 COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,2G3W4@200783|Aquificae 200783|Aquificae P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C CMS3_k127_5730398_0 1237149.C900_04795 3.306e-181 577.0 COG2270@1|root,COG2270@2|Bacteria,4NEKI@976|Bacteroidetes,47JQM@768503|Cytophagia 976|Bacteroidetes S PFAM Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 CMS3_k127_5730398_18 1237149.C900_04796 3.113e-69 237.0 COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,47PP4@768503|Cytophagia 976|Bacteroidetes U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD CMS3_k127_5730398_17 643867.Ftrac_0616 1.278e-69 241.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,47JBU@768503|Cytophagia 976|Bacteroidetes U Biopolymer transport protein ExbD/TolR - - - - - - - - - - - - ExbD CMS3_k127_5730398_28 643867.Ftrac_0617 1.21e-21 98.0 2E2VE@1|root,32XX2@2|Bacteria,4NUIE@976|Bacteroidetes,47RT3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5730398_10 1237149.C900_04800 6.079e-115 376.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,47JQQ@768503|Cytophagia 976|Bacteroidetes U PFAM MotA TolQ ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB CMS3_k127_5730398_29 392499.Swit_3384 2.72e-05 47.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales 204457|Sphingomonadales L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CMS3_k127_5730398_7 1124780.ANNU01000044_gene517 3.207e-137 445.0 COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,47KWG@768503|Cytophagia 976|Bacteroidetes EJ TIGRFAM L-asparaginases, type I ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase CMS3_k127_5730398_13 926556.Echvi_0081 8.972e-96 319.0 COG0084@1|root,COG0084@2|Bacteria,4NEVW@976|Bacteroidetes,47KE3@768503|Cytophagia 976|Bacteroidetes L TIGRFAM hydrolase, TatD family tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase CMS3_k127_5730398_26 1237149.C900_04803 4.793e-38 156.0 COG1215@1|root,COG1215@2|Bacteria,4NKDX@976|Bacteroidetes,47JFA@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 CMS3_k127_5730398_20 929562.Emtol_2802 1.889e-65 229.0 COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,47PE1@768503|Cytophagia 976|Bacteroidetes G PFAM Polysaccharide deacetylase pgdA_1 - - - - - - - - - - - Polysacc_deac_1 CMS3_k127_5730398_4 1237149.C900_04805 2.849e-162 520.0 COG2208@1|root,COG2208@2|Bacteria,4NI98@976|Bacteroidetes,47KA0@768503|Cytophagia 976|Bacteroidetes KT PFAM Stage II sporulation protein E (SpoIIE) - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - SpoIIE CMS3_k127_5730398_19 1124780.ANNU01000044_gene510 1.817e-66 240.0 COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,47KYN@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_5730398_16 643867.Ftrac_3235 1.497e-80 272.0 COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,47PA6@768503|Cytophagia 976|Bacteroidetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC CMS3_k127_5730398_22 1237149.C900_00642 2.665e-54 193.0 COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,47Q95@768503|Cytophagia 976|Bacteroidetes FG HIT family hydrolase hinT - - ko:K02503 - - - - ko00000,ko04147 - - - HIT CMS3_k127_5730398_21 388413.ALPR1_13545 5.957e-60 211.0 COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,47P7N@768503|Cytophagia 976|Bacteroidetes K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N CMS3_k127_5730398_11 1237149.C900_00640 8.609e-111 365.0 COG1357@1|root,COG1357@2|Bacteria,4NY1Q@976|Bacteroidetes,47WKP@768503|Cytophagia 976|Bacteroidetes S Pentapeptide repeats (9 copies) - - - - - - - - - - - - Pentapeptide CMS3_k127_5730398_12 643867.Ftrac_3193 1.905e-103 344.0 COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,47K6J@768503|Cytophagia 976|Bacteroidetes EH D-isomer specific 2-hydroxyacid dehydrogenase serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C CMS3_k127_5730398_2 643867.Ftrac_3194 2.469e-168 540.0 COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,47JTX@768503|Cytophagia 976|Bacteroidetes P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N CMS3_k127_5730398_15 643867.Ftrac_3195 1.131e-82 282.0 COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,47KWT@768503|Cytophagia 976|Bacteroidetes J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD CMS3_k127_5730398_9 1237149.C900_00636 7.322e-127 413.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia 976|Bacteroidetes H Belongs to the PdxA family pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA CMS3_k127_5730398_24 1237149.C900_00634 9.351e-44 165.0 COG1399@1|root,COG1399@2|Bacteria,4NMQT@976|Bacteroidetes,47QNM@768503|Cytophagia 976|Bacteroidetes S Uncharacterized ACR, COG1399 - - - - - - - - - - - - DUF177 CMS3_k127_5730398_27 445970.ALIPUT_01341 3.03e-22 96.0 COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,22UKC@171550|Rikenellaceae 976|Bacteroidetes J Ribosomal L32p protein family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p CMS3_k127_5730398_6 1237149.C900_00632 1.106e-138 446.0 COG0416@1|root,COG0416@2|Bacteria,4NHEX@976|Bacteroidetes,47J9Y@768503|Cytophagia 976|Bacteroidetes I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis CMS3_k127_5730398_3 1121859.KB890757_gene1730 4.673e-165 524.0 COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_5730398_14 1124780.ANNU01000044_gene491 2.998e-92 306.0 COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,47MZS@768503|Cytophagia 976|Bacteroidetes J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CMS3_k127_5730398_23 1356852.N008_19650 1.409e-50 184.0 COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,47PSK@768503|Cytophagia 976|Bacteroidetes I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl CMS3_k127_5741143_8 1237149.C900_03167 5.222e-59 211.0 COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,47JWQ@768503|Cytophagia 976|Bacteroidetes S TPR repeat-containing protein - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8 CMS3_k127_5741143_10 1237149.C900_03184 3.639e-47 175.0 COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_5741143_1 1279009.ADICEAN_00180 3.631e-285 885.0 COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,47KH2@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_5741143_5 1121904.ARBP01000012_gene1348 1.085e-193 610.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JQD@768503|Cytophagia 976|Bacteroidetes I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N CMS3_k127_5741143_0 1237149.C900_04651 0.0 1242.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,47ME4@768503|Cytophagia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 CMS3_k127_5741143_9 1124780.ANNU01000015_gene2018 2.666e-50 182.0 COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,47QHS@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR CMS3_k127_5741143_11 313606.M23134_04780 7.378e-36 141.0 COG1695@1|root,COG1695@2|Bacteria,4NQBA@976|Bacteroidetes,47QGA@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_5741143_2 1237149.C900_04654 1.688e-271 862.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5741143_3 1239962.C943_00386 4.33e-239 764.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5741143_7 1408473.JHXO01000009_gene3381 3.005e-71 247.0 COG3279@1|root,COG3279@2|Bacteria,4NFZT@976|Bacteroidetes 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_5741143_6 1408473.JHXO01000009_gene3380 3.002e-74 262.0 COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,2G2VP@200643|Bacteroidia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c_5,His_kinase CMS3_k127_5741143_13 1408473.JHXO01000009_gene3379 1.088e-24 111.0 2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5741143_4 1237149.C900_03443 4.09e-225 712.0 COG1729@1|root,COG1729@2|Bacteria,4PKMW@976|Bacteroidetes,47JRZ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6,TPR_8 CMS3_k127_5741143_12 1048983.EL17_11790 7.365e-34 145.0 COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,47KXU@768503|Cytophagia 976|Bacteroidetes S Bacterial Ig-like domain - - - - - - - - - - - - Big_5,fn3_3 CMS3_k127_5756453_8 1237149.C900_01850 1.673e-176 566.0 COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 CMS3_k127_5756453_5 1237149.C900_00716 4.017e-223 698.0 COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia 976|Bacteroidetes T PIN domain ybeZ_1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH CMS3_k127_5756453_18 1124780.ANNU01000017_gene1954 1.07e-57 207.0 COG2865@1|root,COG2865@2|Bacteria,4NGPG@976|Bacteroidetes,47N5X@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - AlbA_2 CMS3_k127_5756453_4 1237149.C900_00714 2.375e-232 728.0 COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia 976|Bacteroidetes H magnesium chelatase chlI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - AAA_5,Sigma54_activat CMS3_k127_5756453_7 1237149.C900_00713 1.036e-183 580.0 COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,47K13@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - - - - - - - - - - VWA_2 CMS3_k127_5756453_6 1237149.C900_00709 3.249e-190 599.0 COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,47JT9@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 CMS3_k127_5756453_2 643867.Ftrac_3312 0.0 1076.0 COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47K15@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 N terminal domain - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_5756453_22 1237149.C900_00707 2.211e-17 86.0 2E1YR@1|root,32X7B@2|Bacteria,4NUBX@976|Bacteroidetes,47R5A@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5756453_3 1237149.C900_00706 4.056e-236 744.0 COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,47KZU@768503|Cytophagia 976|Bacteroidetes L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C CMS3_k127_5756453_15 1237149.C900_00705 4.468e-79 272.0 COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,47PBZ@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - 3.4.21.105 ko:K09650 - - - - ko00000,ko01000,ko01002,ko03029 - - - Rhomboid CMS3_k127_5756453_12 1237149.C900_00704 2.518e-101 338.0 COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,47JAM@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_5756453_9 1121904.ARBP01000016_gene5207 4.032e-154 493.0 COG0820@1|root,COG0820@2|Bacteria,4NFH5@976|Bacteroidetes,47KHN@768503|Cytophagia 976|Bacteroidetes J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM CMS3_k127_5756453_1 1237149.C900_05882 0.0 1329.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,47KA7@768503|Cytophagia 976|Bacteroidetes O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N CMS3_k127_5756453_21 762903.Pedsa_0312 6.979e-31 124.0 COG2161@1|root,COG2161@2|Bacteria,4NT64@976|Bacteroidetes,1IUAI@117747|Sphingobacteriia 976|Bacteroidetes D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox CMS3_k127_5756453_20 1250006.JHZZ01000001_gene1694 8.971e-44 160.0 COG4115@1|root,COG4115@2|Bacteria,4NSJD@976|Bacteroidetes,1II7M@117743|Flavobacteriia 976|Bacteroidetes S YoeB-like toxin of bacterial type II toxin-antitoxin system - - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin CMS3_k127_5756453_14 760192.Halhy_5290 2.847e-80 278.0 COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,4NP35@976|Bacteroidetes,1IVW7@117747|Sphingobacteriia 976|Bacteroidetes O COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI,YHS CMS3_k127_5756453_13 760192.Halhy_5289 2.665e-98 333.0 COG3552@1|root,COG3552@2|Bacteria,4NK40@976|Bacteroidetes,1IWRV@117747|Sphingobacteriia 976|Bacteroidetes S COGs COG3552 Protein containing von Willebrand factor type A (vWA) domain - - - ko:K07161 - - - - ko00000 - - - VWA_CoxE CMS3_k127_5756453_10 760192.Halhy_5288 1.372e-118 388.0 COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes,1IW28@117747|Sphingobacteriia 976|Bacteroidetes S SPTR ATPase associated with various cellular activities AAA_5 - - - - - - - - - - - - AAA_5 CMS3_k127_5756453_19 700598.Niako_5157 3.949e-51 188.0 COG3427@1|root,COG3427@2|Bacteria,4NRMQ@976|Bacteroidetes 2|Bacteria S PFAM Carbon monoxide dehydrogenase subunit G (CoxG) coxG - - ko:K09386 - - - - ko00000 - - - COXG CMS3_k127_5756453_0 700598.Niako_5158 0.0 1382.0 COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes,1IVK4@117747|Sphingobacteriia 976|Bacteroidetes C COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.17.1.4,1.2.5.3 ko:K03520,ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_5756453_17 518766.Rmar_2765 3.57e-66 229.0 COG2080@1|root,COG2080@2|Bacteria,4NPTH@976|Bacteroidetes 976|Bacteroidetes C PFAM 2Fe-2S binding - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_5756453_11 700598.Niako_5160 2.835e-116 380.0 COG1319@1|root,COG1319@2|Bacteria,4NFT8@976|Bacteroidetes,1IV94@117747|Sphingobacteriia 976|Bacteroidetes C COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs - - 1.17.1.4,1.2.5.3 ko:K03519,ko:K11178 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS3_k127_5756453_16 1237149.C900_03514 1.511e-70 245.0 COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia 976|Bacteroidetes S TIGRFAM TIGR02453 family protein - - - - - - - - - - - - DUF2461 CMS3_k127_5756453_23 1237149.C900_04608 4.03e-17 82.0 COG2982@1|root,COG2982@2|Bacteria,4NHD3@976|Bacteroidetes,47KTA@768503|Cytophagia 976|Bacteroidetes M AsmA-like C-terminal region - - - - - - - - - - - - AsmA,AsmA_2,DUF3971 CMS3_k127_5758834_1 153721.MYP_4401 3.654e-141 453.0 COG2070@1|root,COG2070@2|Bacteria,4NF8Z@976|Bacteroidetes,47MJV@768503|Cytophagia 976|Bacteroidetes S Nitronate monooxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO CMS3_k127_5758834_0 1237149.C900_03188 2.127e-250 784.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,47M0I@768503|Cytophagia 976|Bacteroidetes P Voltage gated chloride channel clcB - - ko:K03281 - - - - ko00000 2.A.49 - - CBS,Voltage_CLC CMS3_k127_5758834_2 1237149.C900_03187 2.358e-37 145.0 COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,47RGU@768503|Cytophagia 976|Bacteroidetes CO Thioredoxin trxC - - - - - - - - - - - AhpC-TSA,Thioredoxin,Thioredoxin_8 CMS3_k127_5782418_2 1121912.AUHD01000007_gene625 3.723e-35 139.0 COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia 976|Bacteroidetes T Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,TPR_12,TPR_7,TPR_8 CMS3_k127_5782418_0 1237149.C900_00071 0.0 1013.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia 976|Bacteroidetes L DNA polymerase Ligase (LigD) - - - - - - - - - - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N CMS3_k127_5782418_1 1237149.C900_00286 7.117e-102 351.0 COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily addA - - - - - - - - - - - Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C CMS3_k127_5783830_10 706587.Desti_1480 7.997e-17 82.0 COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase bamR - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_5783830_2 1121405.dsmv_3828 1.335e-153 507.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria,2MJ1A@213118|Desulfobacterales 28221|Deltaproteobacteria I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157,1.1.1.35,4.2.1.17 ko:K00074,ko:K15016 ko00360,ko00362,ko00650,ko00720,ko01100,ko01120,ko01200,map00360,map00362,map00650,map00720,map01100,map01120,map01200 M00374,M00375 R01975,R01976,R03026,R05576,R06941 RC00029,RC00117,RC00831 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N CMS3_k127_5783830_5 1198232.CYCME_2333 4.684e-65 229.0 COG1305@1|root,COG1305@2|Bacteria,1R4TK@1224|Proteobacteria,1RYNT@1236|Gammaproteobacteria,461EN@72273|Thiotrichales 72273|Thiotrichales E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core CMS3_k127_5783830_6 485913.Krac_2435 8.57e-46 177.0 COG1319@1|root,COG1319@2|Bacteria 2|Bacteria C xanthine dehydrogenase activity hcrB - 1.3.7.9 ko:K04109 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS3_k127_5783830_1 767817.Desgi_0419 3.354e-195 642.0 COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia 186801|Clostridia C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_5783830_7 1382306.JNIM01000001_gene1022 3.402e-43 182.0 COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi 200795|Chloroflexi C 2Fe-2S -binding domain protein - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_5783830_4 1174504.AJTN02000023_gene4668 4.533e-65 230.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1ZBHS@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabG10 - 1.1.1.100,1.3.1.28 ko:K00059,ko:K00216 ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212 M00083,M00572 R01505,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117,RC00534 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 CMS3_k127_5783830_0 1047013.AQSP01000029_gene2170 2.678e-213 674.0 COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria 2|Bacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 3.5.1.4,6.3.5.6,6.3.5.7 ko:K01426,ko:K02433 ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120 - R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS3_k127_5783830_11 746697.Aeqsu_2760 2.779e-06 59.0 2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia 976|Bacteroidetes S TIR domain - - - - - - - - - - - - TIR_2 CMS3_k127_5783830_9 391603.FBALC1_16767 3.11e-21 106.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1I08N@117743|Flavobacteriia 976|Bacteroidetes T Fis family transcriptional regulator - - - - - - - - - - - - GAF,HTH_8,PAS_3,PAS_9,Response_reg,Sigma54_activat CMS3_k127_5783830_3 1047013.AQSP01000134_gene1348 1.052e-123 428.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5783830_8 1121904.ARBP01000008_gene3400 7.836e-31 125.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 2|Bacteria K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_5804693_16 643867.Ftrac_2495 6.333e-53 194.0 COG2979@1|root,COG2979@2|Bacteria,4PKCN@976|Bacteroidetes 976|Bacteroidetes S LETM1-like protein - - - - - - - - - - - - LETM1 CMS3_k127_5804693_1 1237149.C900_04626 8.316e-229 719.0 COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,47K1F@768503|Cytophagia 976|Bacteroidetes G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N CMS3_k127_5804693_21 1237149.C900_04492 6.077e-36 140.0 2E4SF@1|root,32ZKW@2|Bacteria,4NV4G@976|Bacteroidetes,47RXS@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4783) - - - - - - - - - - - - DUF4783 CMS3_k127_5804693_8 388413.ALPR1_00620 6.15e-98 327.0 COG0157@1|root,COG0157@2|Bacteria,4NDXF@976|Bacteroidetes,47JJ8@768503|Cytophagia 976|Bacteroidetes H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N CMS3_k127_5804693_14 1120966.AUBU01000013_gene407 1.37e-65 227.0 2C88U@1|root,2ZAHP@2|Bacteria,4NK63@976|Bacteroidetes,47NBI@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - YcxB CMS3_k127_5804693_24 1270196.JCKI01000011_gene4233 9.099e-26 112.0 COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1ITI6@117747|Sphingobacteriia 976|Bacteroidetes S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX CMS3_k127_5804693_18 1121904.ARBP01000013_gene450 3.47e-49 179.0 COG3350@1|root,COG3350@2|Bacteria,4NRFU@976|Bacteroidetes,47QIJ@768503|Cytophagia 976|Bacteroidetes S monooxygenase activity - - - - - - - - - - - - YHS CMS3_k127_5804693_19 1237149.C900_04497 3.671e-46 172.0 COG2318@1|root,COG2318@2|Bacteria,4NSP0@976|Bacteroidetes,47R5Z@768503|Cytophagia 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB,DinB_2 CMS3_k127_5804693_6 1185876.BN8_01979 7.353e-107 357.0 COG0189@1|root,COG0189@2|Bacteria,4NH4U@976|Bacteroidetes,47MCV@768503|Cytophagia 976|Bacteroidetes HJ ligase activity - - - - - - - - - - - - RimK CMS3_k127_5804693_20 1237149.C900_04499 3.901e-43 166.0 COG1280@1|root,COG1280@2|Bacteria,4NUV7@976|Bacteroidetes,47SDU@768503|Cytophagia 976|Bacteroidetes E LysE type translocator - - - - - - - - - - - - LysE CMS3_k127_5804693_9 1237149.C900_01804 8.478e-94 321.0 28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,47M50@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 CMS3_k127_5804693_3 313606.M23134_03596 4.644e-149 478.0 COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia 976|Bacteroidetes C Radical SAM - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM CMS3_k127_5804693_7 1237149.C900_01733 6.705e-100 333.0 COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia 976|Bacteroidetes G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CMS3_k127_5804693_28 1237149.C900_01732 3.922e-06 57.0 COG0815@1|root,COG0815@2|Bacteria 2|Bacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase CMS3_k127_5804693_4 1237149.C900_01990 4.71e-127 415.0 COG0664@1|root,COG0745@1|root,COG0664@2|Bacteria,COG0745@2|Bacteria,4NFB1@976|Bacteroidetes,47JY7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, Crp Fnr family crp - - - - - - - - - - - HTH_Crp_2,Response_reg,cNMP_binding CMS3_k127_5804693_5 1237149.C900_01991 7.96e-127 418.0 COG0642@1|root,COG2205@2|Bacteria,4NG0Y@976|Bacteroidetes,47JUV@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9 CMS3_k127_5804693_22 1443665.JACA01000001_gene2640 1.65e-35 146.0 COG0589@1|root,COG0589@2|Bacteria,4NHXF@976|Bacteroidetes,1HY7W@117743|Flavobacteriia,2YIJ8@290174|Aquimarina 976|Bacteroidetes T Universal stress protein family - - - - - - - - - - - - Usp CMS3_k127_5804693_13 926556.Echvi_2464 2.505e-68 242.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp CMS3_k127_5804693_15 1288963.ADIS_0869 7.182e-54 200.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47PIA@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp CMS3_k127_5804693_25 1178825.ALIH01000008_gene789 1.434e-17 87.0 COG0517@1|root,COG0517@2|Bacteria,4NQYH@976|Bacteroidetes,1I24R@117743|Flavobacteriia 976|Bacteroidetes S CBS domain - - - - - - - - - - - - CBS CMS3_k127_5804693_11 1121875.KB907548_gene1380 6.286e-84 284.0 COG1814@1|root,COG1814@2|Bacteria,4NE6W@976|Bacteroidetes,1HZ1U@117743|Flavobacteriia 976|Bacteroidetes S membrane - - - - - - - - - - - - VIT1 CMS3_k127_5804693_17 1286632.P278_23870 1.211e-51 188.0 COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1I1GF@117743|Flavobacteriia 976|Bacteroidetes C cytochrome C - - - - - - - - - - - - Cytochrom_C CMS3_k127_5804693_0 1237149.C900_03372 0.0 1103.0 COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,47KTB@768503|Cytophagia 976|Bacteroidetes C Nitrous oxide reductase nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - - CMS3_k127_5804693_12 1237149.C900_03371 1.875e-80 272.0 COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,47NSZ@768503|Cytophagia 976|Bacteroidetes C lipoprotein involved in nitrous oxide reduction - - - ko:K19342 - - - - ko00000 - - - NosL CMS3_k127_5804693_23 1317122.ATO12_04685 6.815e-35 138.0 COG4314@1|root,COG4314@2|Bacteria,4NVVP@976|Bacteroidetes,1I2Z0@117743|Flavobacteriia,2YJNY@290174|Aquimarina 976|Bacteroidetes C NosL - - - ko:K19342 - - - - ko00000 - - - NosL CMS3_k127_5804693_2 1237149.C900_03369 4.914e-156 502.0 COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,47KEF@768503|Cytophagia 976|Bacteroidetes P Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD CMS3_k127_5804693_10 1122225.AULQ01000005_gene2501 7.769e-88 296.0 COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1HYYD@117743|Flavobacteriia 976|Bacteroidetes V ABC-type multidrug transport system ATPase component - - - ko:K19340 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC_tran CMS3_k127_5804693_26 1237149.C900_03367 3.471e-17 82.0 COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,47KSX@768503|Cytophagia 976|Bacteroidetes S ABC-2 family transporter protein - - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2,ABC2_membrane_5 CMS3_k127_5808536_8 1250278.JQNQ01000001_gene451 1.246e-17 89.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_5808536_0 1237149.C900_02738 1.011e-225 704.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia 976|Bacteroidetes E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT CMS3_k127_5808536_2 1288963.ADIS_2468 1.053e-110 364.0 COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,47KG0@768503|Cytophagia 976|Bacteroidetes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC CMS3_k127_5808536_6 388413.ALPR1_00405 4.68e-59 207.0 COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,47PQK@768503|Cytophagia 976|Bacteroidetes G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB CMS3_k127_5808536_1 1120966.AUBU01000001_gene988 7.322e-121 392.0 COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,47S41@768503|Cytophagia 976|Bacteroidetes F Creatinine amidohydrolase crnA - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase CMS3_k127_5808536_4 1121930.AQXG01000005_gene642 3.939e-74 255.0 COG3751@1|root,COG3751@2|Bacteria,4NFPS@976|Bacteroidetes,1IRWW@117747|Sphingobacteriia 976|Bacteroidetes O 2OG-Fe(II) oxygenase superfamily - - - ko:K07394 - - - - ko00000 - - - 2OG-FeII_Oxy_3,2OG-FeII_Oxy_4 CMS3_k127_5808536_3 1237149.C900_02741 1.581e-88 309.0 28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,47M3Y@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5808536_7 1237149.C900_02742 1.312e-35 139.0 COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,47Q35@768503|Cytophagia 976|Bacteroidetes J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA CMS3_k127_5808536_5 1288963.ADIS_2472 1.238e-67 237.0 COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,47M0Q@768503|Cytophagia 976|Bacteroidetes M ABC-type transport system involved in lipoprotein release permease component lolE_2 - - ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125,3.A.1.15.3,3.A.1.15.5 - - FtsX,MacB_PCD CMS3_k127_5818234_1 1237149.C900_05634 5.2e-68 237.0 COG2197@1|root,COG2197@2|Bacteria,4NR4G@976|Bacteroidetes,47UM2@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg CMS3_k127_5818234_5 1237149.C900_05633 4.081e-45 172.0 COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NHSC@976|Bacteroidetes,47NEM@768503|Cytophagia 976|Bacteroidetes T Two component regulator three Y - - - - - - - - - - - - HATPase_c,HisKA_3,Reg_prop,SpoIIE,Y_Y_Y CMS3_k127_5818234_0 1237149.C900_05420 2.771e-270 840.0 COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia 976|Bacteroidetes C TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 pruA - 1.2.1.88,1.5.5.2 ko:K00294,ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh CMS3_k127_5818234_2 926562.Oweho_3336 1.293e-58 211.0 COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1I188@117743|Flavobacteriia,2PAUK@246874|Cryomorphaceae 976|Bacteroidetes S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED yjjG - - ko:K07025 - - - - ko00000 - - - HAD_2 CMS3_k127_5818234_4 1237149.C900_05422 2.389e-46 169.0 COG0640@1|root,COG0640@2|Bacteria,4NRN0@976|Bacteroidetes,47QVI@768503|Cytophagia 976|Bacteroidetes K arsR family arsR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 CMS3_k127_5818234_3 1237149.C900_05423 1.225e-52 193.0 2BBSK@1|root,325AS@2|Bacteria,4NR2Q@976|Bacteroidetes,47JP3@768503|Cytophagia 976|Bacteroidetes S CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_5857269_7 1237149.C900_01411 1.632e-39 149.0 COG2843@1|root,COG2843@2|Bacteria,4NI6J@976|Bacteroidetes,47NKK@768503|Cytophagia 976|Bacteroidetes M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap CMS3_k127_5857269_6 1237149.C900_01410 2.874e-52 186.0 COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,47R35@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, mercury resistance ycgE - - - - - - - - - - - MerR_1 CMS3_k127_5857269_4 926549.KI421517_gene3600 2.061e-99 335.0 COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,47M2T@768503|Cytophagia 976|Bacteroidetes LU TIGRFAM DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A,HHH_5 CMS3_k127_5857269_3 1237149.C900_01378 1.676e-114 377.0 COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,47KB5@768503|Cytophagia 976|Bacteroidetes E Isopropylmalate homocitrate citramalate synthase mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like CMS3_k127_5857269_2 1121930.AQXG01000003_gene2685 1.61e-156 498.0 COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1IQZ5@117747|Sphingobacteriia 976|Bacteroidetes E Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR CMS3_k127_5857269_0 1237149.C900_01371 0.0 1241.0 COG1410@1|root,COG1410@2|Bacteria,4PKI8@976|Bacteroidetes,47XZT@768503|Cytophagia 976|Bacteroidetes E B12 binding domain metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,DUF559,Met_synt_B12,Pterin_bind CMS3_k127_5857269_1 1237149.C900_00621 5.043e-158 503.0 COG0646@1|root,COG0646@2|Bacteria,4NFRF@976|Bacteroidetes,47KPH@768503|Cytophagia 976|Bacteroidetes E Homocysteine S-methyltransferase metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans CMS3_k127_5857269_5 1237149.C900_03611 5.475e-60 223.0 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - HTH_12,OB_RNB,PSCyt1,RNB,S1,WD40 CMS3_k127_5867500_7 1443665.JACA01000027_gene3925 8.278e-11 70.0 COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes,1HZ2N@117743|Flavobacteriia,2YK2K@290174|Aquimarina 976|Bacteroidetes K Tetratricopeptide repeat - - - - - - - - - - - - GerE,TPR_10,TPR_12,TPR_8 CMS3_k127_5867500_2 944479.JQLX01000002_gene1663 2.679e-41 154.0 COG2329@1|root,COG2329@2|Bacteria,1RHK9@1224|Proteobacteria,43A9C@68525|delta/epsilon subdivisions,2X578@28221|Deltaproteobacteria,2M7F5@213113|Desulfurellales 28221|Deltaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - CMS3_k127_5867500_1 1392498.JQLH01000001_gene1843 9.969e-47 186.0 COG0457@1|root,COG4251@1|root,COG0457@2|Bacteria,COG4251@2|Bacteria,4NI29@976|Bacteroidetes,1HX1A@117743|Flavobacteriia,2PG69@252356|Maribacter 976|Bacteroidetes T Tetratricopeptide repeat - - - - - - - - - - - - HATPase_c,HisKA,TPR_12,TPR_7,TPR_8 CMS3_k127_5867500_4 714943.Mucpa_6005 7.658e-27 112.0 2EM8I@1|root,33EXM@2|Bacteria,4P60J@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5867500_0 1237149.C900_00072 1.176e-114 376.0 COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia 976|Bacteroidetes L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku - - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku CMS3_k127_5867500_3 1237149.C900_00073 1.142e-36 145.0 COG0457@1|root,COG0457@2|Bacteria 1237149.C900_00073|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - CMS3_k127_5867500_5 391896.A1I_00575 1.719e-25 117.0 COG1708@1|root,COG2250@1|root,COG1708@2|Bacteria,COG2250@2|Bacteria,1PWC5@1224|Proteobacteria,2TT5M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S nucleotidyltransferase - - - - - - - - - - - - HEPN,NTP_transf_2 CMS3_k127_5867500_6 1121875.KB907549_gene1905 7.456e-21 93.0 COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes,1I2XY@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 CMS3_k127_5875435_9 1358423.N180_02520 1.932e-48 177.0 COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IQQ6@117747|Sphingobacteriia 976|Bacteroidetes M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 CMS3_k127_5875435_8 1296415.JACC01000033_gene671 5.778e-62 222.0 COG0730@1|root,COG0730@2|Bacteria,4NKE8@976|Bacteroidetes,1II62@117743|Flavobacteriia,2YI1D@290174|Aquimarina 976|Bacteroidetes S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS3_k127_5875435_6 866536.Belba_1888 1.952e-87 293.0 2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia 976|Bacteroidetes S TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - - CMS3_k127_5875435_1 1313301.AUGC01000003_gene2127 0.0 1093.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes 976|Bacteroidetes C SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C CMS3_k127_5875435_5 1124780.ANNU01000020_gene3269 5.434e-131 421.0 COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia 976|Bacteroidetes C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein frdB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_7,Fer4_8 CMS3_k127_5875435_4 868131.MSWAN_1537 4.262e-133 435.0 COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota 28890|Euryarchaeota E PFAM Aminotransferase class I and II - - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 CMS3_k127_5875435_3 1237149.C900_04406 3.369e-133 434.0 COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,47MFH@768503|Cytophagia 976|Bacteroidetes L Belongs to the methyltransferase superfamily - - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 CMS3_k127_5875435_2 1237149.C900_04407 3.139e-271 854.0 COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia 976|Bacteroidetes S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin CMS3_k127_5875435_0 1124780.ANNU01000020_gene3278 0.0 1807.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia 976|Bacteroidetes EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase CMS3_k127_5875435_7 159087.Daro_3006 7.698e-80 285.0 COG0517@1|root,COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2203@1|root,COG0517@2|Bacteria,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,2KZWQ@206389|Rhodocyclales 206389|Rhodocyclales T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K11527 - - - - ko00000,ko01000,ko01001,ko02022 - - - CBS,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,Response_reg CMS3_k127_5900326_6 143224.JQMD01000002_gene4190 2.516e-25 106.0 COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia 976|Bacteroidetes E Aminotransferase, class I - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_5900326_3 643867.Ftrac_2755 1.036e-71 259.0 COG4251@1|root,COG4251@2|Bacteria 2|Bacteria T photoreceptor activity - - 2.1.1.80,3.1.1.61 ko:K13924 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,Y_Y_Y CMS3_k127_5900326_4 1037409.BJ6T_55260 3.321e-45 175.0 COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,3JSH0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Carboxylesterase family - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 CMS3_k127_5900326_5 1123277.KB893172_gene837 1.048e-28 124.0 COG2867@1|root,COG2867@2|Bacteria,4NNHS@976|Bacteroidetes,47P7J@768503|Cytophagia 976|Bacteroidetes I START domain - - - - - - - - - - - - START CMS3_k127_5900326_1 643867.Ftrac_2807 1.215e-136 442.0 COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,47KXF@768503|Cytophagia 976|Bacteroidetes E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase CMS3_k127_5900326_2 643867.Ftrac_3137 1.688e-80 278.0 COG0697@1|root,COG0697@2|Bacteria,4NGZ3@976|Bacteroidetes,47PHD@768503|Cytophagia 976|Bacteroidetes EG EamA-like transporter family - - - - - - - - - - - - EamA CMS3_k127_5900326_0 1237149.C900_03862 2.822e-201 634.0 COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,47JM9@768503|Cytophagia 976|Bacteroidetes L PFAM MgsA AAA ATPase C terminal ycaJ - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CMS3_k127_5944787_17 504487.JCM19302_3816 1.084e-37 147.0 COG2234@1|root,COG2234@2|Bacteria,4NMZ4@976|Bacteroidetes,1HWZ9@117743|Flavobacteriia 976|Bacteroidetes OU Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 CMS3_k127_5944787_21 1124780.ANNU01000078_gene764 3.245e-24 115.0 2BYCP@1|root,2ZAHR@2|Bacteria,4NJ23@976|Bacteroidetes,47NMK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5944787_9 761193.Runsl_0848 1.905e-76 270.0 COG0665@1|root,COG0665@2|Bacteria,4NKQK@976|Bacteroidetes,47Q2W@768503|Cytophagia 976|Bacteroidetes E FAD dependent oxidoreductase - - - - - - - - - - - - DAO CMS3_k127_5944787_16 641524.ADICYQ_0238 1.583e-40 153.0 COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes,47QED@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0145 family - - - - - - - - - - - - YbjQ_1 CMS3_k127_5944787_20 1237149.C900_03168 3.966e-26 111.0 COG4270@1|root,COG4270@2|Bacteria,4NVXH@976|Bacteroidetes,47WJK@768503|Cytophagia 976|Bacteroidetes S Membrane - - - - - - - - - - - - DoxX CMS3_k127_5944787_14 926562.Oweho_3286 1.22e-44 168.0 COG1514@1|root,COG1514@2|Bacteria,4NTUH@976|Bacteroidetes,1I48G@117743|Flavobacteriia 976|Bacteroidetes J 2',5' RNA ligase - - - - - - - - - - - - 2_5_RNA_ligase2 CMS3_k127_5944787_22 1121859.KB890738_gene3684 1.814e-16 85.0 2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5944787_10 1237149.C900_00926 2.194e-76 260.0 COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,47MSF@768503|Cytophagia 976|Bacteroidetes O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ_2 CMS3_k127_5944787_1 1237149.C900_00927 6.419e-320 994.0 COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,47KCK@768503|Cytophagia 976|Bacteroidetes E Aminopeptidase N - - - - - - - - - - - - Peptidase_M1 CMS3_k127_5944787_18 1550091.JROE01000013_gene10 7.915e-37 141.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia 976|Bacteroidetes O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CMS3_k127_5944787_4 1237149.C900_04925 3.305e-144 470.0 COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria,4NEQX@976|Bacteroidetes,47PIJ@768503|Cytophagia 976|Bacteroidetes L TIGRFAM exonuclease, DNA polymerase III, epsilon subunit family - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - GIY-YIG,RNase_T CMS3_k127_5944787_7 880073.Calab_3557 1.124e-95 323.0 COG1215@1|root,COG1215@2|Bacteria,2NQN3@2323|unclassified Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_tranf_2_4,Glycos_transf_2 CMS3_k127_5944787_25 568706.BN118_2057 1.697e-07 60.0 2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,2VSQ3@28216|Betaproteobacteria,3T6ZC@506|Alcaligenaceae 28216|Betaproteobacteria S Domain of unknown function (DUF4136) - - - - - - - - - - - - DUF4136 CMS3_k127_5944787_11 313606.M23134_02357 2.527e-76 262.0 COG3291@1|root,COG3291@2|Bacteria,4NQ3X@976|Bacteroidetes,47SEZ@768503|Cytophagia 976|Bacteroidetes G Legume lectin domain - - - - - - - - - - - - Lectin_legB CMS3_k127_5944787_2 1317122.ATO12_03825 4.235e-175 556.0 COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1HYFP@117743|Flavobacteriia,2YIVD@290174|Aquimarina 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_5944787_8 1382303.JPOM01000001_gene1296 2.703e-86 291.0 COG1028@1|root,COG1028@2|Bacteria,1R8HN@1224|Proteobacteria,2U0TG@28211|Alphaproteobacteria,2KIT0@204458|Caulobacterales 204458|Caulobacterales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CMS3_k127_5944787_0 1123073.KB899245_gene56 0.0 1495.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria,1X46E@135614|Xanthomonadales 135614|Xanthomonadales L Helicase lhr1 - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C CMS3_k127_5944787_13 643867.Ftrac_2579 4.559e-48 189.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - CMS3_k127_5944787_15 1237149.C900_03158 1.224e-42 162.0 COG0500@1|root,COG0500@2|Bacteria,4NFUU@976|Bacteroidetes,47QDJ@768503|Cytophagia 976|Bacteroidetes Q Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_11 CMS3_k127_5944787_5 1237149.C900_05514 2.93e-141 458.0 COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia 976|Bacteroidetes E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - 2.5.1.48,4.4.1.8 ko:K01739,ko:K01760 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_5944787_3 1305737.JAFX01000001_gene3280 2.48e-174 555.0 COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,47JG0@768503|Cytophagia 976|Bacteroidetes F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CMS3_k127_5944787_6 1313301.AUGC01000001_gene1456 1.432e-112 388.0 COG0747@1|root,COG4288@1|root,COG0747@2|Bacteria,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes 976|Bacteroidetes E Lamin Tail Domain - - - - - - - - - - - - Big_5,CHU_C,LTD CMS3_k127_5950492_20 1121859.KB890740_gene3855 4.856e-09 58.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_5950492_10 1237149.C900_00826 6.897e-65 227.0 2DZGZ@1|root,32VAD@2|Bacteria,4NSFP@976|Bacteroidetes,47RS7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - ATP-synt_10 CMS3_k127_5950492_17 515635.Dtur_0601 3.029e-44 169.0 COG2135@1|root,COG2135@2|Bacteria 2|Bacteria S peptidase activity yoqW - - - - - - - - - - - SRAP CMS3_k127_5950492_16 1237149.C900_05299 1.298e-48 188.0 COG1073@1|root,COG1073@2|Bacteria,4NP3H@976|Bacteroidetes 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 CMS3_k127_5950492_8 1237149.C900_05503 9.281e-92 308.0 28JIP@1|root,2Z82C@2|Bacteria,4NFN9@976|Bacteroidetes,47PJT@768503|Cytophagia 976|Bacteroidetes S S1 P1 nuclease - - - - - - - - - - - - S1-P1_nuclease CMS3_k127_5950492_19 1237149.C900_00141 4.152e-10 66.0 297RM@1|root,2ZUYF@2|Bacteria,4P83I@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - KTSC CMS3_k127_5950492_11 1250232.JQNJ01000001_gene3289 1.674e-61 221.0 COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1HYN3@117743|Flavobacteriia 976|Bacteroidetes S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 CMS3_k127_5950492_9 1313421.JHBV01000013_gene3740 3.613e-79 276.0 COG1028@1|root,COG1028@2|Bacteria 1313421.JHBV01000013_gene3740|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - CMS3_k127_5950492_7 1313421.JHBV01000013_gene3741 5.114e-99 336.0 2DBBP@1|root,2Z88Z@2|Bacteria 2|Bacteria S Sulfo-transferase - - - - - - - - - - - - Sulfotransfer_3 CMS3_k127_5950492_4 1313421.JHBV01000013_gene3742 9.134e-152 489.0 COG5361@1|root,COG5361@2|Bacteria 2|Bacteria P Conserved Protein - - - - - - - - - - - - DUF1214 CMS3_k127_5950492_0 1237149.C900_00918 0.0 1540.0 COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia 976|Bacteroidetes L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF CMS3_k127_5950492_6 1237149.C900_00920 9.423e-113 367.0 COG3279@1|root,COG3279@2|Bacteria,4NFWA@976|Bacteroidetes,47N62@768503|Cytophagia 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_5950492_5 1237149.C900_00921 6.555e-119 392.0 COG2972@1|root,COG2972@2|Bacteria,4NI09@976|Bacteroidetes,47K66@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase CMS3_k127_5950492_3 1279009.ADICEAN_01935 6.102e-205 644.0 COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,47JSB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated lipoprotein GldJ gldJ - - - - - - - - - - - FGE-sulfatase CMS3_k127_5950492_14 1121957.ATVL01000011_gene3756 1.095e-52 193.0 COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,47PYN@768503|Cytophagia 976|Bacteroidetes S TIGRFAM comF family protein comF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Pribosyltran CMS3_k127_5950492_13 926549.KI421517_gene1046 9.532e-53 187.0 COG0599@1|root,COG0599@2|Bacteria,4NNRB@976|Bacteroidetes,47QTE@768503|Cytophagia 976|Bacteroidetes S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD CMS3_k127_5950492_15 643867.Ftrac_2383 5.108e-51 183.0 29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,47R44@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5950492_1 1237149.C900_03437 0.0 1089.0 COG1196@1|root,COG1196@2|Bacteria,4NF7P@976|Bacteroidetes,47NNE@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - DUF4175 CMS3_k127_5950492_12 1279009.ADICEAN_01763 1.195e-58 205.0 COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase rsbW - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 CMS3_k127_5950492_18 1279009.ADICEAN_01762 4.575e-40 153.0 COG0319@1|root,COG0319@2|Bacteria,4NS93@976|Bacteroidetes,47Q9Q@768503|Cytophagia 976|Bacteroidetes S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - - - - - - - - - - UPF0054 CMS3_k127_5950492_2 1124780.ANNU01000015_gene1981 1.305e-289 897.0 COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes,47JCG@768503|Cytophagia 976|Bacteroidetes D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc CMS3_k127_5978501_3 1379270.AUXF01000001_gene2153 9.634e-115 383.0 2BS4J@1|root,32M5G@2|Bacteria,1ZUJX@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - CMS3_k127_5978501_6 929562.Emtol_2321 7.809e-39 151.0 COG0457@1|root,COG0457@2|Bacteria,4NRIH@976|Bacteroidetes,47QEH@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_5978501_2 1120965.AUBV01000004_gene847 5.501e-157 506.0 COG0006@1|root,COG0006@2|Bacteria,4NJI0@976|Bacteroidetes 976|Bacteroidetes E xaa-pro dipeptidase K01271 pepQ - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 CMS3_k127_5978501_4 866536.Belba_0530 3.246e-86 295.0 COG0457@1|root,COG0457@2|Bacteria,4NJ7M@976|Bacteroidetes,47N78@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_6,TPR_8 CMS3_k127_5978501_5 1185876.BN8_04246 1.493e-63 221.0 COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,47QER@768503|Cytophagia 976|Bacteroidetes O Peptidyl-prolyl cis-trans isomerase slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C CMS3_k127_5978501_0 1096769.Pelub83DRAFT_1332 3.208e-179 576.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,4BPQM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Respiratory-chain NADH dehydrogenase 51 Kd subunit fdsB - 1.17.1.9,1.6.5.3 ko:K00122,ko:K00124,ko:K00335 ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200 M00144 R00519,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB CMS3_k127_5978501_1 485916.Dtox_3503 4.036e-170 556.0 COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,260KC@186807|Peptococcaceae 186801|Clostridia C TIGRFAM formate dehydrogenase, alpha subunit nuoG - 1.17.1.10,1.6.5.3 ko:K00336,ko:K05299 ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200 M00144,M00377 R00134,R11945 RC00061,RC02796 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 CMS3_k127_5988403_3 1094715.CM001373_gene1338 4.603e-06 51.0 2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - CMS3_k127_5988403_0 1237149.C900_04785 5.805e-185 585.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JKI@768503|Cytophagia 976|Bacteroidetes T CheY-like receiver AAA-type ATPase and DNA-binding domains ntrX - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_5988403_1 1121899.Q764_02660 3.684e-98 330.0 COG1541@1|root,COG1541@2|Bacteria,4PKAN@976|Bacteroidetes,1HX4F@117743|Flavobacteriia,2NSIU@237|Flavobacterium 976|Bacteroidetes H acyl transferase luxE - - - - - - - - - - - LuxE CMS3_k127_5988403_2 1124780.ANNU01000044_gene526 1.688e-35 144.0 2E691@1|root,32WA1@2|Bacteria,4NT8M@976|Bacteroidetes,47R10@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6004311_14 1239962.C943_04449 3.084e-27 126.0 COG0526@1|root,COG0526@2|Bacteria,4NH2A@976|Bacteroidetes,47RPZ@768503|Cytophagia 976|Bacteroidetes O Thiol-disulfide isomerase-like thioredoxin - - - - - - - - - - - - AhpC-TSA,Redoxin,Thioredoxin_8 CMS3_k127_6004311_2 1237149.C900_01149 3.098e-219 698.0 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia 976|Bacteroidetes E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 CMS3_k127_6004311_0 1237149.C900_01151 0.0 1208.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia 976|Bacteroidetes C FAD linked oxidases, C-terminal domain - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8 CMS3_k127_6004311_11 643867.Ftrac_2275 1.704e-52 189.0 COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,47PEH@768503|Cytophagia 976|Bacteroidetes M Cell wall-associated hydrolase (invasion-associated protein) spr - - ko:K13695 - - - - ko00000,ko01002 - - - LysM,NLPC_P60 CMS3_k127_6004311_3 1237149.C900_02383 2.85e-217 685.0 28KRY@1|root,2ZA9E@2|Bacteria,4NI1H@976|Bacteroidetes,47N4R@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6004311_10 1237149.C900_02382 1.461e-65 226.0 COG0784@1|root,COG0784@2|Bacteria,4NRC9@976|Bacteroidetes,47QC7@768503|Cytophagia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_6004311_1 1237149.C900_02381 1.021e-250 781.0 COG1012@1|root,COG1012@2|Bacteria,4NFPJ@976|Bacteroidetes,47JJR@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family pcd - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_6004311_7 1237149.C900_02380 8.196e-160 516.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia 976|Bacteroidetes O PDZ domain (Also known as DHR or GLGF) htrA - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 CMS3_k127_6004311_13 643867.Ftrac_2445 2.322e-33 135.0 COG0071@1|root,COG0071@2|Bacteria,4NSJB@976|Bacteroidetes,47R4W@768503|Cytophagia 976|Bacteroidetes O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS3_k127_6004311_5 1237149.C900_03794 7.627e-161 517.0 COG1914@1|root,COG1914@2|Bacteria,4NEG8@976|Bacteroidetes,47TDM@768503|Cytophagia 976|Bacteroidetes P Mn2 and Fe2 transporters of the NRAMP family - - - - - - - - - - - - Nramp CMS3_k127_6004311_8 1121104.AQXH01000001_gene1400 2.384e-157 511.0 COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS3_k127_6004311_6 1121104.AQXH01000001_gene1400 6.137e-160 521.0 COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS3_k127_6004311_4 314278.NB231_13636 2.063e-190 607.0 2DUQG@1|root,33RR5@2|Bacteria 2|Bacteria S HCO3- transporter family - - - - - - - - - - - - HCO3_cotransp CMS3_k127_6004311_17 485918.Cpin_1422 2.596e-15 84.0 2C2QD@1|root,33JG0@2|Bacteria,4PQ05@976|Bacteroidetes,1IZHI@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6004311_9 580332.Slit_2572 5.138e-66 231.0 arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS3_k127_6004311_16 643867.Ftrac_1316 4.051e-24 106.0 2E1V4@1|root,32X4G@2|Bacteria,4NTMM@976|Bacteroidetes,47RT0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6004311_15 1317122.ATO12_16070 2.101e-24 109.0 COG1595@1|root,COG1595@2|Bacteria,4NU6U@976|Bacteroidetes,1I42V@117743|Flavobacteriia,2YH0U@290174|Aquimarina 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6004311_12 1237149.C900_03902 3.331e-36 145.0 2EK5G@1|root,33DVX@2|Bacteria,4PA8R@976|Bacteroidetes,47SYN@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4405) - - - - - - - - - - - - DUF4405 CMS3_k127_6007819_3 1237149.C900_04875 1.514e-120 396.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia 976|Bacteroidetes N ABC transporter substrate-binding component GldG gldG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux CMS3_k127_6007819_2 1237149.C900_04873 1.097e-200 629.0 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,47M1J@768503|Cytophagia 976|Bacteroidetes L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 CMS3_k127_6007819_1 1120968.AUBX01000016_gene1682 4.278e-206 648.0 COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,47JQ7@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase CMS3_k127_6007819_4 1237149.C900_04865 4.632e-75 257.0 28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,47PZX@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4290) - - - - - - - - - - - - DUF4290 CMS3_k127_6007819_0 1237149.C900_04864 0.0 1142.0 COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,47JMH@768503|Cytophagia 976|Bacteroidetes L PFAM UvrD REP helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C CMS3_k127_6016506_1 1237149.C900_00387 1.588e-210 665.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6016506_7 1124780.ANNU01000006_gene2855 2.179e-57 209.0 COG3595@1|root,COG3595@2|Bacteria,4NGRU@976|Bacteroidetes,47MSM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4097 CMS3_k127_6016506_6 1237149.C900_00391 4.501e-68 241.0 COG3595@1|root,COG3595@2|Bacteria,4NJBA@976|Bacteroidetes,47MRP@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6016506_9 926549.KI421517_gene2974 7.334e-45 172.0 COG1413@1|root,COG1413@2|Bacteria,4NIBA@976|Bacteroidetes,47M5K@768503|Cytophagia 976|Bacteroidetes C HEAT repeats - - - - - - - - - - - - HEAT_2,zf-HC2 CMS3_k127_6016506_8 1237149.C900_00393 3.161e-57 205.0 COG1595@1|root,COG1595@2|Bacteria,4NMYQ@976|Bacteroidetes,47PII@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6016506_5 643867.Ftrac_2367 1.217e-74 261.0 COG0596@1|root,COG0596@2|Bacteria,4PNPN@976|Bacteroidetes,47XAU@768503|Cytophagia 976|Bacteroidetes S Ndr family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 CMS3_k127_6016506_10 926549.KI421517_gene1149 7.76e-27 116.0 297E6@1|root,2ZUMN@2|Bacteria,4NPTI@976|Bacteroidetes,47R84@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_6016506_3 504728.K649_14710 9.427e-136 443.0 COG0446@1|root,COG0446@2|Bacteria 2|Bacteria Q pyridine nucleotide-disulphide oxidoreductase sqr GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS3_k127_6016506_4 1237149.C900_00401 9.63e-83 278.0 COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,47PI0@768503|Cytophagia 976|Bacteroidetes O Redoxin - - - - - - - - - - - - AhpC-TSA CMS3_k127_6016506_2 1313421.JHBV01000020_gene5217 2.198e-164 529.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes 976|Bacteroidetes E COG0076 Glutamate decarboxylase and related PLP-dependent - - - - - - - - - - - - Pyridoxal_deC CMS3_k127_6016506_0 643867.Ftrac_2261 5.897e-222 713.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_6027906_1 1047013.AQSP01000134_gene1348 1.849e-124 421.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6027906_0 760192.Halhy_4062 3.228e-205 665.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6027906_3 1206741.BAFX01000133_gene1790 8.292e-54 197.0 COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4FYZY@85025|Nocardiaceae 201174|Actinobacteria IQ KR domain - - - - - - - - - - - - adh_short CMS3_k127_6027906_4 1237149.C900_04030 1.354e-44 169.0 2DMMQ@1|root,32SHK@2|Bacteria,4NSZY@976|Bacteroidetes,47R9F@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF3052 CMS3_k127_6027906_2 880071.Fleli_2859 1.658e-94 329.0 COG2203@1|root,COG2208@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3292@2|Bacteria,4NKGA@976|Bacteroidetes,47TQU@768503|Cytophagia 976|Bacteroidetes T Stage II sporulation protein E (SpoIIE) - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,Reg_prop,SpoIIE,Y_Y_Y CMS3_k127_6028166_2 1227739.Hsw_1068 9.102e-197 621.0 COG0161@1|root,COG0161@2|Bacteria,4PMIJ@976|Bacteroidetes,47Q50@768503|Cytophagia 976|Bacteroidetes H Aminotransferase class-III - - 2.6.1.55 ko:K15372 ko00410,ko00430,ko01100,map00410,map00430,map01100 - R00908,R01684 RC00006,RC00062 ko00000,ko00001,ko01000 - - - Aminotran_3 CMS3_k127_6028166_0 1227739.Hsw_1070 3.722e-221 696.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47MNC@768503|Cytophagia 976|Bacteroidetes C Aldehyde dehydrogenase family mmsA - 1.2.1.18,1.2.1.27 ko:K00140,ko:K22187 ko00040,ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00040,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935,R11768 RC00004,RC00080,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_6028166_5 1122137.AQXF01000004_gene1784 3.729e-145 478.0 COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria 28211|Alphaproteobacteria K metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - Amidohydro_3 CMS3_k127_6028166_11 1237149.C900_03740 2.507e-63 231.0 28J2U@1|root,2Z8Z5@2|Bacteria,4NHYM@976|Bacteroidetes,47RCK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6028166_14 861299.J421_5994 8.363e-32 134.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase_3 CMS3_k127_6028166_1 313603.FB2170_04440 6.092e-200 632.0 COG1757@1|root,COG1757@2|Bacteria,4NFF8@976|Bacteroidetes,1IIVD@117743|Flavobacteriia 976|Bacteroidetes C Na H antiporter mleN - - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter CMS3_k127_6028166_4 313603.FB2170_04435 2.494e-168 537.0 COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1IJ8Q@117743|Flavobacteriia,2PGAH@252356|Maribacter 976|Bacteroidetes E Cys/Met metabolism PLP-dependent enzyme - - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_6028166_8 313603.FB2170_06845 1.027e-99 334.0 COG2423@1|root,COG2423@2|Bacteria,4NHUM@976|Bacteroidetes,1I0J2@117743|Flavobacteriia 976|Bacteroidetes E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall CMS3_k127_6028166_6 1137281.D778_00277 1.671e-131 428.0 COG3938@1|root,COG3938@2|Bacteria,4NJMD@976|Bacteroidetes,1HZXF@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the proline racemase family - - 5.1.1.4 ko:K01777 ko00330,ko01100,map00330,map01100 - R01255 RC00479 ko00000,ko00001,ko01000 - - - Pro_racemase CMS3_k127_6028166_10 1007103.AFHW01000025_gene361 8.225e-76 278.0 COG1555@1|root,COG1555@2|Bacteria,1VTMY@1239|Firmicutes 1239|Firmicutes L COG1555 DNA uptake protein and related DNA-binding proteins - - - - - - - - - - - - HHH_3 CMS3_k127_6028166_3 929703.KE386491_gene1728 2.266e-183 601.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47M0S@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_6028166_12 1506583.JQJY01000003_gene3279 3.603e-39 154.0 2E47Q@1|root,32Z3K@2|Bacteria,4NU6R@976|Bacteroidetes,1I5A6@117743|Flavobacteriia,2NVT3@237|Flavobacterium 976|Bacteroidetes S Domain of unknown function (DUF4919) - - - - - - - - - - - - DUF4919 CMS3_k127_6028166_7 1123276.KB893245_gene1776 1.679e-120 396.0 28K3C@1|root,2Z9SH@2|Bacteria,4NKA2@976|Bacteroidetes,47NBG@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6028166_9 388413.ALPR1_12080 6.388e-80 280.0 28PTH@1|root,2ZCER@2|Bacteria,4NN6T@976|Bacteroidetes,47PQ4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6028166_13 1168034.FH5T_07590 8.314e-37 143.0 COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes,2FSQZ@200643|Bacteroidia 976|Bacteroidetes S DoxX family - - - ko:K15977 - - - - ko00000 - - - DoxX CMS3_k127_6030522_0 946077.W5A_08702 0.0 1286.0 COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1IJ5T@117743|Flavobacteriia 976|Bacteroidetes P TonB-dependent receptor plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6030522_6 946077.W5A_08707 6.386e-176 564.0 COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,1HWZF@117743|Flavobacteriia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like,SusD-like_2 CMS3_k127_6030522_9 1279009.ADICEAN_00477 3.004e-51 198.0 COG3063@1|root,COG3063@2|Bacteria 2|Bacteria NU photosynthesis - - - ko:K20543 - - - - ko00000,ko02000 1.B.55.3 - - BCSC_C,DUF560,TPR_16,TPR_19,TPR_8 CMS3_k127_6030522_13 1121904.ARBP01000003_gene6469 4.086e-20 93.0 COG5349@1|root,COG5349@2|Bacteria,4PK9G@976|Bacteroidetes,47VRS@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF983) - - - - - - - - - - - - DUF983 CMS3_k127_6030522_11 1122176.KB903609_gene5121 4.962e-33 137.0 COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,1ISVK@117747|Sphingobacteriia 976|Bacteroidetes S Cytochrome C biogenesis protein transmembrane region - - - ko:K09792 - - - - ko00000 - - - DsbD_2 CMS3_k127_6030522_12 1237149.C900_03362 2.83e-23 104.0 COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia 976|Bacteroidetes S FixH ccoH - - ko:K09926 - - - - ko00000 - - - FixH CMS3_k127_6030522_5 1237149.C900_03363 2.45e-181 578.0 COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia 976|Bacteroidetes C TIGRFAM cytochrome c oxidase accessory protein ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C CMS3_k127_6030522_8 1237149.C900_03364 4.104e-78 271.0 COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia 976|Bacteroidetes C TIGRFAM cytochrome c oxidase, cbb3-type, subunit III ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N CMS3_k127_6030522_1 1237149.C900_03366 0.0 1225.0 COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia 976|Bacteroidetes C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1,FixO CMS3_k127_6030522_15 1121930.AQXG01000002_gene2265 6.756e-10 61.0 COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1IUIX@117747|Sphingobacteriia 976|Bacteroidetes P TIGRFAM cytochrome oxidase maturation protein, cbb3-type ccoS - - - - - - - - - - - FixS CMS3_k127_6030522_4 1237149.C900_03383 1.175e-217 700.0 COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia 976|Bacteroidetes P ATPase, P-type (transporting), HAD superfamily, subfamily IC ccoI - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase CMS3_k127_6030522_2 643867.Ftrac_0556 0.0 1057.0 COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,47MF6@768503|Cytophagia 976|Bacteroidetes S Belongs to the peptidase M16 family pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_6030522_7 153721.MYP_3445 1.317e-123 407.0 COG3675@1|root,COG3675@2|Bacteria,4PKPE@976|Bacteroidetes 976|Bacteroidetes I Lipase (class 3) - - - - - - - - - - - - Lipase_3 CMS3_k127_6030522_10 1250232.JQNJ01000001_gene1652 6.519e-48 177.0 2DM9Y@1|root,32AJ6@2|Bacteria,4NQQC@976|Bacteroidetes,1I336@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6030522_3 313606.M23134_06058 7.2e-279 871.0 COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia 976|Bacteroidetes EU Dipeptidyl peptidase IV (DPP IV) N-terminal region - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 CMS3_k127_6047080_6 1296415.JACC01000006_gene1508 2.179e-22 102.0 COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1I3K8@117743|Flavobacteriia,2YKQM@290174|Aquimarina 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_6047080_7 1279009.ADICEAN_02486 3.708e-17 95.0 COG2010@1|root,COG2010@2|Bacteria,4P8QV@976|Bacteroidetes 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C CMS3_k127_6047080_3 1168034.FH5T_05155 3.803e-95 331.0 COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes 976|Bacteroidetes C Quinol cytochrome c oxidoreductase - - - - - - - - - - - - Cytochrom_C,Cytochrom_CIII,Cytochrome_C7 CMS3_k127_6047080_0 1168034.FH5T_05160 0.0 1039.0 COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes 976|Bacteroidetes C Quinol cytochrome c oxidoreductase nrfC - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molydop_binding CMS3_k127_6047080_1 1168034.FH5T_05165 3.536e-203 641.0 COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes 976|Bacteroidetes C Pfam Polysulphide reductase, NrfD nrfD - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD CMS3_k127_6047080_5 1168034.FH5T_05170 2.68e-23 105.0 COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes 976|Bacteroidetes C Quinol cytochrome c oxidoreductase membrane protein actD - - - - - - - - - - - DUF3341 CMS3_k127_6047080_4 1168034.FH5T_05175 3.199e-51 189.0 COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes 976|Bacteroidetes C Cytochrome C actE - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_6047080_2 1168034.FH5T_05180 6.654e-126 413.0 COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes 976|Bacteroidetes P Quinol cytochrome c oxidoreductase actF - - - - - - - - - - - - CMS3_k127_6056357_8 1408473.JHXO01000006_gene1349 9.404e-67 243.0 COG1538@1|root,COG1538@2|Bacteria,4NFSW@976|Bacteroidetes,2FNYU@200643|Bacteroidia 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_6056357_9 1408473.JHXO01000006_gene1347 7.616e-38 149.0 COG1309@1|root,COG1309@2|Bacteria,4NIBT@976|Bacteroidetes,2FU2E@200643|Bacteroidia 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CMS3_k127_6056357_14 1120951.AUBG01000017_gene3281 4.307e-14 80.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia 976|Bacteroidetes M Opacity protein - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_6056357_11 1121904.ARBP01000012_gene1205 9.642e-34 138.0 2EHTV@1|root,33BJH@2|Bacteria,4NZPA@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6056357_6 1121904.ARBP01000012_gene1206 1.876e-111 370.0 COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,47PNV@768503|Cytophagia 976|Bacteroidetes M Surface antigen - - - - - - - - - - - - Bac_surface_Ag CMS3_k127_6056357_4 1237149.C900_04641 6.86e-141 452.0 COG3000@1|root,COG3000@2|Bacteria,4NGQA@976|Bacteroidetes,47JWM@768503|Cytophagia 976|Bacteroidetes I Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase CMS3_k127_6056357_13 926549.KI421517_gene1364 2.624e-15 81.0 COG4103@1|root,COG4103@2|Bacteria,4NUAN@976|Bacteroidetes,47R5X@768503|Cytophagia 976|Bacteroidetes S Tellurite resistance protein TerB - - - - - - - - - - - - - CMS3_k127_6056357_0 1237149.C900_00549 4.709e-307 951.0 COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,47KPX@768503|Cytophagia 976|Bacteroidetes G Glucosamine-6-phosphate isomerase nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso,PIG-L CMS3_k127_6056357_7 1123278.KB893561_gene3160 9.401e-90 304.0 COG0583@1|root,COG0583@2|Bacteria,4NHTU@976|Bacteroidetes,47U15@768503|Cytophagia 976|Bacteroidetes K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CMS3_k127_6056357_5 700598.Niako_4376 2.441e-121 400.0 COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1ITTX@117747|Sphingobacteriia 976|Bacteroidetes E Pyridoxal-phosphate dependent enzyme - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS3_k127_6056357_1 1392498.JQLH01000001_gene2549 3.288e-302 939.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia,2PGPF@252356|Maribacter 976|Bacteroidetes EU Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_6056357_2 1237149.C900_00949 7.596e-183 588.0 COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,47KQH@768503|Cytophagia 976|Bacteroidetes OU signal peptide peptidase SppA, 36K type sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 CMS3_k127_6056357_10 1123277.KB893172_gene799 1.917e-35 141.0 COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,47QG8@768503|Cytophagia 976|Bacteroidetes H TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK,dNK CMS3_k127_6056357_3 1120968.AUBX01000017_gene1952 5.472e-141 452.0 COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,47JDE@768503|Cytophagia 976|Bacteroidetes I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 CMS3_k127_6056357_12 762903.Pedsa_2898 4.5e-25 105.0 COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1ITBQ@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 CMS3_k127_6066714_1 1317122.ATO12_14095 5.235e-20 92.0 COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,1HYBE@117743|Flavobacteriia,2YHKK@290174|Aquimarina 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_6066714_0 44689.DDB0233096 2.465e-260 824.0 COG0474@1|root,KOG0204@2759|Eukaryota,3XAKI@554915|Amoebozoa 554915|Amoebozoa P This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium - - - - - - - - - - - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CMS3_k127_6070213_13 1117108.PAALTS15_11079 0.0001243 51.0 COG0103@1|root,COG0103@2|Bacteria,1VAS8@1239|Firmicutes,4HNSF@91061|Bacilli,26T3Z@186822|Paenibacillaceae 91061|Bacilli J Copper amine oxidase N-terminal domain - - - - - - - - - - - - Cu_amine_oxidN1,VWA CMS3_k127_6070213_8 926549.KI421517_gene4105 3.55e-72 250.0 COG2133@1|root,COG2133@2|Bacteria,4NGMS@976|Bacteroidetes,47KFU@768503|Cytophagia 976|Bacteroidetes G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_6070213_7 153721.MYP_18 8.844e-75 258.0 COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,47M1W@768503|Cytophagia 976|Bacteroidetes H Belongs to the ComB family comB - 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 - - - 2-ph_phosp CMS3_k127_6070213_1 1237149.C900_03998 1.232e-177 562.0 COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,47MN7@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C CMS3_k127_6070213_9 1237149.C900_01864 1.668e-52 196.0 COG1073@1|root,COG1073@2|Bacteria,4NGDK@976|Bacteroidetes,47Q3Y@768503|Cytophagia 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4 CMS3_k127_6070213_6 1122947.FR7_1058 3.635e-78 269.0 COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4H7AN@909932|Negativicutes 909932|Negativicutes S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 CMS3_k127_6070213_12 1185876.BN8_05038 1.458e-51 187.0 2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,47RDY@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_6070213_5 313606.M23134_00570 3.41e-91 307.0 COG0010@1|root,COG0010@2|Bacteria,4NHDP@976|Bacteroidetes,47UNV@768503|Cytophagia 976|Bacteroidetes E Arginase family - - - - - - - - - - - - Arginase CMS3_k127_6070213_11 1121904.ARBP01000002_gene7061 1.395e-51 192.0 28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,47QT8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6070213_2 1270193.JARP01000006_gene1674 2.874e-150 492.0 COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia,2NVGY@237|Flavobacterium 976|Bacteroidetes P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Sulfatase CMS3_k127_6070213_4 1237149.C900_04049 2.071e-96 322.0 COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,47THR@768503|Cytophagia 976|Bacteroidetes L Endonuclease/Exonuclease/phosphatase family xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos CMS3_k127_6070213_3 518766.Rmar_1743 8.353e-118 387.0 COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes 976|Bacteroidetes G Xylose isomerase - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_6070213_10 1123277.KB893201_gene6424 4.706e-52 189.0 COG0262@1|root,COG0262@2|Bacteria,4NJIQ@976|Bacteroidetes,47PHT@768503|Cytophagia 976|Bacteroidetes H RibD C-terminal domain - - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - RibD_C CMS3_k127_6070213_0 1121904.ARBP01000005_gene4643 8.204e-225 718.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_6074735_12 1237149.C900_00607 6.041e-66 234.0 2DN4I@1|root,32VGS@2|Bacteria,4NNY4@976|Bacteroidetes,47RGS@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_6074735_1 1237149.C900_00608 3.821e-317 988.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47JN3@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6074735_7 926556.Echvi_3887 2.501e-100 337.0 COG0429@1|root,COG0429@2|Bacteria,4NFGZ@976|Bacteroidetes,47JJP@768503|Cytophagia 976|Bacteroidetes S Alpha beta hydrolase - - - ko:K07019 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4 CMS3_k127_6074735_11 1279009.ADICEAN_02403 2.428e-71 247.0 COG2135@1|root,COG2135@2|Bacteria,4NKPN@976|Bacteroidetes,47MR7@768503|Cytophagia 976|Bacteroidetes S Belongs to the SOS response-associated peptidase family - - - - - - - - - - - - SRAP CMS3_k127_6074735_5 926556.Echvi_3889 4.369e-157 501.0 COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,47JAR@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_6074735_4 1279009.ADICEAN_03512 4.977e-176 568.0 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,47JTG@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 CMS3_k127_6074735_9 1123277.KB893194_gene5831 1.308e-80 277.0 COG1073@1|root,COG1073@2|Bacteria,4NNXQ@976|Bacteroidetes,47PV9@768503|Cytophagia 976|Bacteroidetes S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 CMS3_k127_6074735_14 1279009.ADICEAN_02917 4.536e-36 141.0 2CJFR@1|root,32RQT@2|Bacteria,4NVPU@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6074735_0 1237149.C900_02668 0.0 1084.0 COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,47KK6@768503|Cytophagia 976|Bacteroidetes S glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C CMS3_k127_6074735_3 866536.Belba_2255 7.199e-178 567.0 COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,47MPX@768503|Cytophagia 976|Bacteroidetes J TIGRFAM MiaB-like tRNA modifying enzyme yqeV - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 CMS3_k127_6074735_13 290512.Paes_1486 6.142e-65 237.0 COG0577@1|root,COG0577@2|Bacteria,1FDBN@1090|Chlorobi 1090|Chlorobi V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6074735_2 1237149.C900_04746 1.957e-229 714.0 2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,47MEQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6074735_8 1237149.C900_04747 6.268e-87 292.0 COG4445@1|root,COG4445@2|Bacteria,4NFY4@976|Bacteroidetes,47P6J@768503|Cytophagia 976|Bacteroidetes FJ Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA miaE - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE CMS3_k127_6074735_6 1237149.C900_04748 2.181e-119 406.0 COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,47JRI@768503|Cytophagia 976|Bacteroidetes H Putative porin - - - - - - - - - - - - Porin_10 CMS3_k127_6074735_10 153721.MYP_534 4.618e-79 273.0 COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,47M44@768503|Cytophagia 976|Bacteroidetes M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK CMS3_k127_6190498_2 1237149.C900_00606 1.804e-224 707.0 COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47P0R@768503|Cytophagia 976|Bacteroidetes S Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 CMS3_k127_6190498_0 1223410.KN050846_gene286 0.0 1313.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia 976|Bacteroidetes M Peptidase M16 - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_6190498_3 1237149.C900_00597 6.405e-220 716.0 COG0823@1|root,COG0823@2|Bacteria,4NGPR@976|Bacteroidetes,47MQP@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - CMS3_k127_6190498_4 153721.MYP_4667 2.198e-218 689.0 COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47KP4@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS3_k127_6190498_7 1237149.C900_00595 6.076e-92 304.0 COG5405@1|root,COG5405@2|Bacteria,4NHZ8@976|Bacteroidetes,47MJS@768503|Cytophagia 976|Bacteroidetes O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome CMS3_k127_6190498_10 1121904.ARBP01000002_gene7285 1.512e-41 156.0 COG1393@1|root,COG1393@2|Bacteria,4NSA6@976|Bacteroidetes 976|Bacteroidetes P Belongs to the ArsC family arsC - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC CMS3_k127_6190498_1 1121904.ARBP01000016_gene5220 0.0 1180.0 COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia 976|Bacteroidetes Q PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 CMS3_k127_6190498_5 1121904.ARBP01000016_gene5221 3.204e-140 458.0 COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 CMS3_k127_6190498_9 1121007.AUML01000016_gene212 1.872e-42 162.0 COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I28Y@117743|Flavobacteriia,2YK1A@290174|Aquimarina 976|Bacteroidetes S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 CMS3_k127_6190498_6 1408433.JHXV01000007_gene2938 4.754e-99 327.0 COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,1HXG3@117743|Flavobacteriia,2PAW2@246874|Cryomorphaceae 976|Bacteroidetes P Carbonic anhydrase cah - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA CMS3_k127_6190498_11 643867.Ftrac_2337 4.543e-23 100.0 2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 CMS3_k127_6190498_8 391598.FBBAL38_01755 3.765e-71 246.0 COG0664@1|root,COG0664@2|Bacteria,4NNT7@976|Bacteroidetes,1I1XI@117743|Flavobacteriia 976|Bacteroidetes K CRP FNR family transcriptional regulator - - - ko:K01420 - - - - ko00000,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding CMS3_k127_6212670_3 643867.Ftrac_1445 9.533e-11 63.0 COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,47RGU@768503|Cytophagia 976|Bacteroidetes CO Thioredoxin trxC - - - - - - - - - - - AhpC-TSA,Thioredoxin,Thioredoxin_8 CMS3_k127_6212670_0 1185876.BN8_03552 7.61e-67 233.0 COG0526@1|root,COG0526@2|Bacteria,4PKPR@976|Bacteroidetes,47PBI@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA CMS3_k127_6212670_4 1408433.JHXV01000004_gene3484 1.654e-09 68.0 COG1506@1|root,COG1506@2|Bacteria,4NKM9@976|Bacteroidetes,1I0MY@117743|Flavobacteriia 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 CMS3_k127_6212670_2 1237149.C900_02267 6.382e-17 83.0 COG0454@1|root,COG0456@2|Bacteria,4NPYR@976|Bacteroidetes,47USJ@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 CMS3_k127_6212670_1 1237149.C900_04542 3.157e-43 159.0 COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,47KAH@768503|Cytophagia 976|Bacteroidetes IQ PFAM GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 CMS3_k127_6231720_17 385682.AFSL01000035_gene2943 3.317e-20 92.0 COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,2FM8D@200643|Bacteroidia,3XJA3@558415|Marinilabiliaceae 976|Bacteroidetes G Alpha-L-fucosidase C-terminal domain - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,Fucosidase_C CMS3_k127_6231720_9 999419.HMPREF1077_03149 5.304e-109 360.0 COG0501@1|root,COG0501@2|Bacteria,4PIP6@976|Bacteroidetes,2FPH4@200643|Bacteroidia,22ZDM@171551|Porphyromonadaceae 976|Bacteroidetes O Peptidase family M48 htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 CMS3_k127_6231720_13 226186.BT_1198 2.294e-76 260.0 COG1704@1|root,COG1704@2|Bacteria,4NMP9@976|Bacteroidetes,2FRGD@200643|Bacteroidia,4AN7A@815|Bacteroidaceae 976|Bacteroidetes S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA CMS3_k127_6231720_5 1121898.Q766_14475 9.09e-165 529.0 COG0402@1|root,COG0402@2|Bacteria,4NG64@976|Bacteroidetes,1I0FD@117743|Flavobacteriia,2NYMY@237|Flavobacterium 976|Bacteroidetes F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_6231720_12 313606.M23134_03504 4.932e-88 298.0 COG3741@1|root,COG3741@2|Bacteria,4NIN9@976|Bacteroidetes,47UJG@768503|Cytophagia 976|Bacteroidetes E N-formylglutamate amidohydrolase - - - - - - - - - - - - FGase CMS3_k127_6231720_8 1122222.AXWR01000035_gene208 6.077e-118 392.0 COG0520@1|root,COG0520@2|Bacteria,1WIPV@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_5 CMS3_k127_6231720_18 373903.Hore_03740 2.803e-14 80.0 COG1309@1|root,COG2355@1|root,COG1309@2|Bacteria,COG2355@2|Bacteria,1V8M2@1239|Firmicutes,24J7T@186801|Clostridia 186801|Clostridia K tetR family - - - - - - - - - - - - TetR_N CMS3_k127_6231720_20 1122176.KB903540_gene33 1.462e-11 73.0 2ABP6@1|root,31153@2|Bacteria,4NQ16@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6231720_19 1229487.AMYW01000001_gene3873 7.23e-12 76.0 COG3209@1|root,COG4886@1|root,COG5184@1|root,COG3209@2|Bacteria,COG4886@2|Bacteria,COG5184@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia,2P052@237|Flavobacterium 976|Bacteroidetes M leucine- rich repeat protein - - - - - - - - - - - - LRR_4,Laminin_G_3,RCC1,SprB CMS3_k127_6231720_7 929562.Emtol_3627 8.351e-124 404.0 COG1171@1|root,COG1171@2|Bacteria,4NEY2@976|Bacteroidetes,47KNZ@768503|Cytophagia 976|Bacteroidetes E Pyridoxal-phosphate dependent enzyme ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS3_k127_6231720_1 880070.Cycma_2089 0.0 1112.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 CMS3_k127_6231720_16 1237149.C900_00817 1.218e-38 149.0 COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,47S2U@768503|Cytophagia 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB CMS3_k127_6231720_3 1237149.C900_00818 2.172e-214 678.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia 976|Bacteroidetes J Amidase - - - - - - - - - - - - Amidase CMS3_k127_6231720_4 1124780.ANNU01000078_gene767 1.411e-187 602.0 COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes,47M7Z@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 CMS3_k127_6231720_15 1121904.ARBP01000006_gene3784 2.334e-58 208.0 COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,47PFV@768503|Cytophagia 976|Bacteroidetes C Nitroreductase family ydjA - - - - - - - - - - - Nitroreductase CMS3_k127_6231720_14 1237149.C900_01543 3.271e-71 247.0 COG0500@1|root,COG2226@2|Bacteria,4NM9E@976|Bacteroidetes,47PMX@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 CMS3_k127_6231720_0 926556.Echvi_0867 0.0 1365.0 COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,47JVJ@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA1 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - AAA_21,ABC_tran CMS3_k127_6231720_2 1237149.C900_01521 6.519e-222 694.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47MQD@768503|Cytophagia 976|Bacteroidetes E Belongs to the Glu Leu Phe Val dehydrogenases family gdh GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009986,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N CMS3_k127_6231720_11 588596.U9UMD6 3.598e-101 340.0 COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi 4751|Fungi Q Dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS3_k127_6231720_6 926562.Oweho_2328 7.792e-149 492.0 COG0672@1|root,COG2010@1|root,COG0672@2|Bacteria,COG2010@2|Bacteria,4NKBD@976|Bacteroidetes,1I04I@117743|Flavobacteriia 976|Bacteroidetes C High-affinity Fe2 Pb2 permease - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - Cytochrome_CBB3,FTR1 CMS3_k127_6231720_10 1237149.C900_04536 5.496e-102 338.0 COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia 976|Bacteroidetes G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM CMS3_k127_6373223_2 1237149.C900_03367 1.042e-89 301.0 COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,47KSX@768503|Cytophagia 976|Bacteroidetes S ABC-2 family transporter protein - - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2,ABC2_membrane_5 CMS3_k127_6373223_4 521097.Coch_0431 1.848e-52 190.0 COG0454@1|root,COG0456@2|Bacteria,4NP1E@976|Bacteroidetes,1I26T@117743|Flavobacteriia,1ESUJ@1016|Capnocytophaga 976|Bacteroidetes K Acetyltransferase (GNAT) domain paiA - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1 CMS3_k127_6373223_1 755732.Fluta_3954 2.063e-122 399.0 COG0596@1|root,COG0596@2|Bacteria,4NM26@976|Bacteroidetes 976|Bacteroidetes S Hydrolase or acyltransferase (Alpha beta hydrolase superfamily)-like protein - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 CMS3_k127_6373223_5 1237149.C900_03225 4.148e-35 136.0 2C9BK@1|root,32RP1@2|Bacteria,4NSPA@976|Bacteroidetes,47RVQ@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4286) - - - - - - - - - - - - DUF4286 CMS3_k127_6373223_3 1123057.P872_01715 6.848e-61 213.0 COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia 976|Bacteroidetes K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_6373223_0 1237149.C900_03228 1.535e-303 945.0 COG1505@1|root,COG1505@2|Bacteria,4NFJS@976|Bacteroidetes,47JBG@768503|Cytophagia 976|Bacteroidetes E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain pep GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 ko:K01322 ko04614,map04614 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N CMS3_k127_6373223_6 468059.AUHA01000002_gene1205 1.323e-05 47.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,1IQMK@117747|Sphingobacteriia 976|Bacteroidetes J seryl-tRNA synthetase serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b CMS3_k127_6384572_3 1123277.KB893195_gene5693 1.782e-151 509.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6384572_16 1121904.ARBP01000017_gene5134 6.04e-24 105.0 COG1695@1|root,COG1695@2|Bacteria,4P6G7@976|Bacteroidetes,47VZ7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_6384572_7 926562.Oweho_0685 2.154e-127 419.0 COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1HWMB@117743|Flavobacteriia,2PAJU@246874|Cryomorphaceae 976|Bacteroidetes L Belongs to the DEAD box helicase family deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C CMS3_k127_6384572_8 1124780.ANNU01000002_gene1620 4.04e-115 377.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS3_k127_6384572_6 1550091.JROE01000008_gene3610 2.255e-139 451.0 COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,1IPKV@117747|Sphingobacteriia 976|Bacteroidetes I PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_6384572_15 1392490.JHZX01000001_gene696 5.319e-33 131.0 COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,1I4FM@117743|Flavobacteriia 976|Bacteroidetes S Cupin domain protein - - - - - - - - - - - - Cupin_2 CMS3_k127_6384572_10 1120965.AUBV01000013_gene1342 1.763e-86 289.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,47PAR@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 CMS3_k127_6384572_9 643867.Ftrac_0518 4.519e-106 351.0 COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia 976|Bacteroidetes S UPF0365 protein - - - - - - - - - - - - YdfA_immunity CMS3_k127_6384572_5 1239962.C943_04256 9.86e-142 458.0 COG3239@1|root,COG3239@2|Bacteria,4NERD@976|Bacteroidetes,47JP1@768503|Cytophagia 976|Bacteroidetes I fatty acid desaturase - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS3_k127_6384572_2 929556.Solca_0268 4.589e-154 516.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6384572_14 929556.Solca_2127 4.295e-41 156.0 COG2020@1|root,COG2020@2|Bacteria,4PGXX@976|Bacteroidetes,1IUNY@117747|Sphingobacteriia 976|Bacteroidetes O Phospholipid methyltransferase - - - - - - - - - - - - PEMT CMS3_k127_6384572_4 313603.FB2170_15763 2.227e-149 480.0 COG0500@1|root,COG2226@2|Bacteria,4NE69@976|Bacteroidetes,1HZ10@117743|Flavobacteriia,2PIJN@252356|Maribacter 976|Bacteroidetes Q O-methyltransferase - - - - - - - - - - - - Methyltransf_31 CMS3_k127_6384572_12 1121904.ARBP01000006_gene3738 3.643e-82 279.0 COG3279@1|root,COG3279@2|Bacteria,4NNIK@976|Bacteroidetes,47XE1@768503|Cytophagia 976|Bacteroidetes K PFAM response regulator receiver - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_6384572_11 886379.AEWI01000012_gene1124 4.616e-83 287.0 COG2972@1|root,COG2972@2|Bacteria,4NG34@976|Bacteroidetes,2G2V6@200643|Bacteroidia,3XJSN@558415|Marinilabiliaceae 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c_5,His_kinase CMS3_k127_6384572_0 929703.KE386491_gene1945 3.733e-277 881.0 COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 CMS3_k127_6384572_18 1227268.HMPREF1552_02300 4.967e-16 86.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase paiA - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 CMS3_k127_6384572_1 1185876.BN8_04092 2.885e-208 667.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia 976|Bacteroidetes EU Dienelactone hydrolase family - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 CMS3_k127_6384572_13 485918.Cpin_1001 1.508e-48 186.0 COG4782@1|root,COG4782@2|Bacteria,4NS8M@976|Bacteroidetes 976|Bacteroidetes S Alpha/beta hydrolase of unknown function (DUF900) - - - - - - - - - - - - DUF900 CMS3_k127_64043_4 1279009.ADICEAN_03003 7.338e-15 75.0 COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,47JZ3@768503|Cytophagia 976|Bacteroidetes D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA CMS3_k127_64043_2 1237149.C900_00264 2.902e-32 127.0 COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,47RA0@768503|Cytophagia 976|Bacteroidetes O NifU domain protein nfuA - - - - - - - - - - - NifU CMS3_k127_64043_0 1237149.C900_00263 7.038e-208 682.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47JD6@768503|Cytophagia 976|Bacteroidetes O PFAM Pregnancy-associated plasma protein-A fpp2 - - - - - - - - - - - Peptidase_M43 CMS3_k127_64043_1 1237149.C900_00262 2.01e-107 358.0 COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,47M8U@768503|Cytophagia 976|Bacteroidetes F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N CMS3_k127_64043_3 1237149.C900_00261 3.521e-32 129.0 COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,47KQI@768503|Cytophagia 976|Bacteroidetes S PFAM PASTA domain spk1 - 2.7.11.1,6.3.2.4 ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01001,ko01011 - - - PASTA CMS3_k127_6443104_1 1237149.C900_03200 1.197e-305 955.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,47JV4@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG CMS3_k127_6443104_8 1237149.C900_02753 9.929e-186 591.0 COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia 976|Bacteroidetes P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH CMS3_k127_6443104_6 1237149.C900_02752 7.631e-197 621.0 COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,47NY5@768503|Cytophagia 976|Bacteroidetes P TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N CMS3_k127_6443104_2 1048983.EL17_12760 4.8e-277 861.0 COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,47JC8@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon CMS3_k127_6443104_34 1279009.ADICEAN_02028 6.87e-31 128.0 2E7DW@1|root,331WY@2|Bacteria,4NUZQ@976|Bacteroidetes,47SM5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6443104_32 866536.Belba_1495 4.838e-53 190.0 COG0590@1|root,COG0590@2|Bacteria,4NNJ2@976|Bacteroidetes,47PPY@768503|Cytophagia 976|Bacteroidetes FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 CMS3_k127_6443104_18 1121859.KB890756_gene1470 5.436e-101 331.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,47JJV@768503|Cytophagia 976|Bacteroidetes P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N CMS3_k127_6443104_37 641524.ADICYQ_3720 2.925e-23 105.0 2F6K2@1|root,33Z2Y@2|Bacteria,4P4F1@976|Bacteroidetes,47VH0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6443104_0 1237149.C900_02379 0.0 1034.0 COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,47KBV@768503|Cytophagia 976|Bacteroidetes L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB CMS3_k127_6443104_25 1004149.AFOE01000059_gene369 2.771e-71 248.0 COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia 976|Bacteroidetes E Shikimate aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N CMS3_k127_6443104_14 1237149.C900_02374 9.846e-113 371.0 COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,47MKT@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 CMS3_k127_6443104_12 1237149.C900_02373 3.203e-139 445.0 COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,47MRM@768503|Cytophagia 976|Bacteroidetes S PFAM (2R)-phospho-3-sulfolactate synthase ComA - - 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 - - - ComA CMS3_k127_6443104_7 1237149.C900_02372 1.824e-189 602.0 COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,47M8A@768503|Cytophagia 976|Bacteroidetes NU PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 CMS3_k127_6443104_19 1237149.C900_02371 7.218e-97 326.0 COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,47M93@768503|Cytophagia 976|Bacteroidetes M PFAM NAD dependent epimerase dehydratase family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase,NAD_binding_4 CMS3_k127_6443104_26 1237149.C900_02370 1.735e-67 237.0 COG4464@1|root,COG4464@2|Bacteria,4NMUT@976|Bacteroidetes,47PBY@768503|Cytophagia 976|Bacteroidetes GM capsular polysaccharide biosynthesis protein - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - CMS3_k127_6443104_9 1237149.C900_02369 4.833e-184 601.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz CMS3_k127_6443104_35 1237149.C900_02368 1.769e-30 130.0 COG1596@1|root,COG1596@2|Bacteria,4NPJB@976|Bacteroidetes,47Q04@768503|Cytophagia 976|Bacteroidetes M Polysaccharide biosynthesis/export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export CMS3_k127_6443104_13 643867.Ftrac_2679 5.698e-115 383.0 COG0438@1|root,COG0707@1|root,COG0438@2|Bacteria,COG0707@2|Bacteria,4NEX8@976|Bacteroidetes,47KFQ@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase 4-like - - - ko:K13004 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 CMS3_k127_6443104_33 1121373.KB903620_gene2049 6.811e-40 156.0 COG2010@1|root,COG2010@2|Bacteria,4NSUK@976|Bacteroidetes,47R5S@768503|Cytophagia 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3,SirB CMS3_k127_6443104_11 643867.Ftrac_2681 5.248e-157 503.0 COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,47JGI@768503|Cytophagia 976|Bacteroidetes S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 CMS3_k127_6443104_20 1396141.BATP01000044_gene1481 8.521e-93 320.0 COG4941@1|root,COG4941@2|Bacteria,46SEY@74201|Verrucomicrobia,2IV8H@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2 CMS3_k127_6443104_36 1121904.ARBP01000026_gene656 6.295e-29 121.0 COG3795@1|root,COG3795@2|Bacteria,4NS2I@976|Bacteroidetes,47RFW@768503|Cytophagia 976|Bacteroidetes S YCII-related domain - - - - - - - - - - - - YCII CMS3_k127_6443104_21 1237149.C900_02777 4.147e-92 311.0 COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,47MRR@768503|Cytophagia 976|Bacteroidetes EG PFAM EamA-like transporter family fjo11 - - - - - - - - - - - EamA CMS3_k127_6443104_10 1124780.ANNU01000006_gene2835 2.509e-161 514.0 COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia 976|Bacteroidetes J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus CMS3_k127_6443104_23 1237149.C900_02779 1.576e-74 264.0 COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,47JZ8@768503|Cytophagia 976|Bacteroidetes S PFAM CAAX amino terminal protease family - - - ko:K07052 - - - - ko00000 - - - Abi CMS3_k127_6443104_38 742817.HMPREF9449_01181 1.664e-10 63.0 2A7I2@1|root,30WFU@2|Bacteria,4PIFY@976|Bacteroidetes,2FW2Z@200643|Bacteroidia,2317Y@171551|Porphyromonadaceae 976|Bacteroidetes S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 CMS3_k127_6443104_16 1124780.ANNU01000006_gene2832 9.92e-109 358.0 COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,47KPM@768503|Cytophagia 976|Bacteroidetes S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 CMS3_k127_6443104_5 643867.Ftrac_2764 2.485e-230 717.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47K4Z@768503|Cytophagia 976|Bacteroidetes E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N CMS3_k127_6443104_22 1124780.ANNU01000006_gene2830 1.285e-82 280.0 COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,47MWN@768503|Cytophagia 976|Bacteroidetes I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase CMS3_k127_6443104_28 1279009.ADICEAN_04251 1.63e-63 221.0 COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia 976|Bacteroidetes T GAF domain-containing protein msrC - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF,GAF_2 CMS3_k127_6443104_17 1120965.AUBV01000004_gene930 1.326e-108 361.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,4NFJE@976|Bacteroidetes,47KBG@768503|Cytophagia 976|Bacteroidetes H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 CMS3_k127_6443104_30 1237149.C900_02786 6.083e-62 224.0 COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,47PXV@768503|Cytophagia 976|Bacteroidetes J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS CMS3_k127_6443104_3 926559.JoomaDRAFT_3890 1.283e-253 792.0 COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia 976|Bacteroidetes E peptidase M1 - - - - - - - - - - - - Peptidase_M1 CMS3_k127_6443104_4 1189612.A33Q_4294 1.228e-233 747.0 COG4772@1|root,COG4772@2|Bacteria,4PKTE@976|Bacteroidetes,47KHE@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug Domain - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6443104_29 485918.Cpin_0719 2.091e-63 223.0 COG3172@1|root,COG3172@2|Bacteria,4NFNZ@976|Bacteroidetes,1ISIF@117747|Sphingobacteriia 976|Bacteroidetes H ATPase kinase involved in NAD metabolism nadR - - - - - - - - - - - AAA_28 CMS3_k127_6443104_24 1237149.C900_03143 2.432e-72 249.0 COG3201@1|root,COG3201@2|Bacteria,4NFJI@976|Bacteroidetes,47R6S@768503|Cytophagia 976|Bacteroidetes H TIGRFAM Nicotinamide mononucleotide transporter PnuC pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter CMS3_k127_6443104_31 643867.Ftrac_2829 3.183e-59 213.0 COG1512@1|root,COG1512@2|Bacteria 2|Bacteria S TPM domain - - - - - - - - - - - - - CMS3_k127_6443104_27 1237149.C900_03139 4.615e-65 231.0 COG0797@1|root,COG0797@2|Bacteria,4NSF1@976|Bacteroidetes,47RE3@768503|Cytophagia 976|Bacteroidetes M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR CMS3_k127_6443104_15 1121904.ARBP01000007_gene2914 8.851e-110 359.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,47KQV@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH CMS3_k127_6459500_3 1123248.KB893359_gene2011 2.383e-51 188.0 COG0558@1|root,COG0558@2|Bacteria,4NHGH@976|Bacteroidetes,1IT19@117747|Sphingobacteriia 976|Bacteroidetes I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf CMS3_k127_6459500_4 1123248.KB893359_gene2031 7.137e-49 192.0 COG1503@1|root,COG1503@2|Bacteria,4NHF3@976|Bacteroidetes,1IQW9@117747|Sphingobacteriia 976|Bacteroidetes J translation release factor activity - - - - - - - - - - - - - CMS3_k127_6459500_2 1336803.PHEL49_0727 1.466e-57 207.0 COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,1I19C@117743|Flavobacteriia,3VX98@52959|Polaribacter 976|Bacteroidetes S Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - Pribosyltran CMS3_k127_6459500_6 1121033.AUCF01000014_gene1347 4.147e-31 128.0 COG3685@1|root,COG3685@2|Bacteria,1REKN@1224|Proteobacteria,2U73U@28211|Alphaproteobacteria,2JWRW@204441|Rhodospirillales 204441|Rhodospirillales S Domain of unknown function (DUF892) - - - - - - - - - - - - DUF892 CMS3_k127_6459500_0 1296415.JACC01000006_gene1529 2.218e-217 698.0 COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,1I00H@117743|Flavobacteriia,2YKC6@290174|Aquimarina 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_6459500_1 1189620.AJXL01000008_gene2272 4.034e-122 401.0 COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,1HYXX@117743|Flavobacteriia,2NT8C@237|Flavobacterium 976|Bacteroidetes G beta-1,4-mannooligosaccharide phosphorylase - - 2.4.1.339,2.4.1.340,3.2.1.197 ko:K20885,ko:K21065 - - R11397,R11398,R11544 RC00049,RC02748 ko00000,ko01000 - GH130 - Glyco_hydro_130 CMS3_k127_6459500_5 643867.Ftrac_0166 3.201e-36 148.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,47XGI@768503|Cytophagia 976|Bacteroidetes T Universal stress protein family - - - - - - - - - - - - Usp CMS3_k127_6558215_0 1121887.AUDK01000003_gene2716 1.213e-53 198.0 2DKFZ@1|root,309D6@2|Bacteria,4NEGR@976|Bacteroidetes,1HZN8@117743|Flavobacteriia,2NVIV@237|Flavobacterium 976|Bacteroidetes S Domain of unknown function (DUF4382) - - - - - - - - - - - - CarboxypepD_reg,DUF4382 CMS3_k127_6558215_2 388413.ALPR1_13979 2.153e-34 134.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QZJ@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_6558215_1 1237149.C900_05787 2.491e-46 178.0 COG0577@1|root,COG0577@2|Bacteria,4P1B0@976|Bacteroidetes,47U89@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - MacB_PCD CMS3_k127_6593356_0 313603.FB2170_12151 0.0 1257.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1HYRS@117743|Flavobacteriia,2PH4D@252356|Maribacter 976|Bacteroidetes S Insulinase (Peptidase family M16) - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_6593356_2 643867.Ftrac_1104 1.064e-06 52.0 COG4249@1|root,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes,47UFX@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 CMS3_k127_6593356_1 616991.JPOO01000003_gene644 2.557e-206 655.0 COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1HZPZ@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 CMS3_k127_6672433_1 616991.JPOO01000003_gene2291 4.183e-31 130.0 COG2159@1|root,COG2159@2|Bacteria,4PJ9Q@976|Bacteroidetes,1IEPW@117743|Flavobacteriia,23IFH@178469|Arenibacter 976|Bacteroidetes S amidohydrolase - - - - - - - - - - - - - CMS3_k127_6672433_5 1237149.C900_00913 2.732e-08 60.0 COG0666@1|root,COG0666@2|Bacteria,4NEYY@976|Bacteroidetes,47MVD@768503|Cytophagia 976|Bacteroidetes U Ankyrin repeats (3 copies) - - - - - - - - - - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5,Lipocalin_5,SecA_DEAD CMS3_k127_6672433_2 1121875.KB907550_gene698 2.177e-13 80.0 COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia 976|Bacteroidetes U WD40-like Beta Propeller - - - - - - - - - - - - PD40 CMS3_k127_6672433_4 5911.EAS01143 3.379e-10 72.0 COG0457@1|root,KOG0585@1|root,KOG0548@2759|Eukaryota,KOG0585@2759|Eukaryota,KOG1840@2759|Eukaryota 2759|Eukaryota C determination of stomach left/right asymmetry - - 2.7.11.1 ko:K10407,ko:K14861,ko:K21157 ko04138,ko05132,map04138,map05132 - - - ko00000,ko00001,ko01000,ko01001,ko03009,ko03019,ko04812 - - - Pkinase,TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_6672433_0 1192124.LIG30_1791 8.926e-157 501.0 COG0604@1|root,COG0604@2|Bacteria,1R8NX@1224|Proteobacteria,2W0KY@28216|Betaproteobacteria,1K4PK@119060|Burkholderiaceae 28216|Betaproteobacteria C Alcohol dehydrogenase GroES-like domain - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 CMS3_k127_6672433_6 866536.Belba_0364 2.973e-06 55.0 2DSJJ@1|root,33GER@2|Bacteria,4NZAF@976|Bacteroidetes,47UN4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6672433_3 153721.MYP_358 1.46e-10 62.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS3_k127_6705087_10 643867.Ftrac_2138 1.363e-88 295.0 COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,47JMK@768503|Cytophagia 976|Bacteroidetes E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CMS3_k127_6705087_9 1250006.JHZZ01000001_gene109 1.342e-95 326.0 COG2265@1|root,COG2265@2|Bacteria,4PKBS@976|Bacteroidetes,1HXP3@117743|Flavobacteriia,3VVXI@52959|Polaribacter 976|Bacteroidetes J RNA cap guanine-N2 methyltransferase - - - - - - - - - - - - Cons_hypoth95,Methyltransf_15 CMS3_k127_6705087_0 1237149.C900_01780 0.0 1217.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,47KGB@768503|Cytophagia 976|Bacteroidetes J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N CMS3_k127_6705087_2 1237149.C900_01779 6.32e-229 713.0 COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,47KFI@768503|Cytophagia 976|Bacteroidetes K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 CMS3_k127_6705087_11 1237149.C900_01778 1.678e-31 130.0 COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,47R9C@768503|Cytophagia 976|Bacteroidetes S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C CMS3_k127_6705087_1 643867.Ftrac_2446 4.648e-235 735.0 COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,47MAW@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e CMS3_k127_6705087_8 1124780.ANNU01000005_gene2549 9.818e-114 376.0 COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase family M28 ywaD - - - - - - - - - - - Peptidase_M28 CMS3_k127_6705087_7 485918.Cpin_0181 2.089e-133 430.0 COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IPV3@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CMS3_k127_6705087_5 880526.KE386488_gene863 3.748e-142 458.0 COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia,22UWX@171550|Rikenellaceae 976|Bacteroidetes M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd CMS3_k127_6705087_6 1124780.ANNU01000005_gene2368 2.163e-136 441.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,47JM5@768503|Cytophagia 976|Bacteroidetes M PFAM NAD dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd CMS3_k127_6705087_4 1453500.AT05_10680 2.716e-170 539.0 COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1HWT7@117743|Flavobacteriia 976|Bacteroidetes GM PFAM NAD dependent epimerase dehydratase family - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd CMS3_k127_6705087_3 1279009.ADICEAN_01104 1.257e-195 617.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,47KAG@768503|Cytophagia 976|Bacteroidetes M Belongs to the UDP-glucose GDP-mannose dehydrogenase family tuaD - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N CMS3_k127_6707684_6 1237149.C900_05257 1.258e-28 118.0 29N3N@1|root,33SHJ@2|Bacteria,4P1XQ@976|Bacteroidetes,47TMQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6707684_1 1237149.C900_05294 4.712e-264 835.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_6707684_2 1267211.KI669560_gene568 2.627e-170 550.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IWU5@117747|Sphingobacteriia 976|Bacteroidetes I AMP-binding enzyme - - - - - - - - - - - - AMP-binding CMS3_k127_6707684_5 1267211.KI669560_gene569 2.236e-54 198.0 COG0204@1|root,COG0204@2|Bacteria,4NNG7@976|Bacteroidetes,1IYKW@117747|Sphingobacteriia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_6707684_3 1237149.C900_04080 8.582e-120 387.0 COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,47N33@768503|Cytophagia 976|Bacteroidetes V ABC transporter - - - - - - - - - - - - ABC_tran CMS3_k127_6707684_4 1237149.C900_04079 1.761e-80 284.0 COG1538@1|root,COG1538@2|Bacteria,4NU3A@976|Bacteroidetes,47P0C@768503|Cytophagia 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_6707684_0 1124780.ANNU01000036_gene53 2.389e-296 923.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,47JD4@768503|Cytophagia 976|Bacteroidetes J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 CMS3_k127_670879_1 1047013.AQSP01000095_gene2303 1.248e-89 309.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_670879_3 1123277.KB893172_gene964 8.192e-54 203.0 COG2207@1|root,COG2207@2|Bacteria,4NIIK@976|Bacteroidetes,47MA0@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 CMS3_k127_670879_2 760192.Halhy_3762 5.497e-82 278.0 COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1IQ8R@117747|Sphingobacteriia 976|Bacteroidetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_670879_0 760192.Halhy_3763 4.986e-138 467.0 COG0577@1|root,COG0577@2|Bacteria,4P3C0@976|Bacteroidetes 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX CMS3_k127_670879_4 665571.STHERM_c15490 3.959e-31 129.0 2E8ZQ@1|root,33397@2|Bacteria,2J942@203691|Spirochaetes 203691|Spirochaetes - - - - - - - - - - - - - - - CMS3_k127_6723527_1 886379.AEWI01000082_gene1599 7.94e-40 164.0 COG3179@1|root,COG3179@2|Bacteria,4NF8K@976|Bacteroidetes 976|Bacteroidetes M fibronectin type III domain protein - - - - - - - - - - - - fn3 CMS3_k127_6723527_0 1237149.C900_03741 8.584e-130 418.0 COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01692,ko:K01715 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_6723527_2 240302.BN982_02812 9.775e-11 63.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,3NEZS@45667|Halobacillus 91061|Bacilli T Low molecular weight phosphatase family yfkJ - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc CMS3_k127_6730859_10 1121904.ARBP01000010_gene2450 7.372e-83 279.0 COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,47KCQ@768503|Cytophagia 976|Bacteroidetes E Tryptophan 2,3-dioxygenase kynA - 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase CMS3_k127_6730859_0 1237149.C900_05076 2.273e-237 737.0 COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,47KQK@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_6730859_8 1237149.C900_03719 1.701e-95 324.0 2CG1Y@1|root,2Z9QX@2|Bacteria,4NJI6@976|Bacteroidetes,47PFJ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 CMS3_k127_6730859_4 1237149.C900_03717 3.409e-149 477.0 COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b CMS3_k127_6730859_14 1237149.C900_05647 4.906e-42 158.0 2DN0J@1|root,32UI3@2|Bacteria,4NT4U@976|Bacteroidetes,47R55@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6730859_3 1313301.AUGC01000006_gene67 1.346e-192 606.0 COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes 976|Bacteroidetes E 4-hydroxyphenylpyruvate dioxygenase hppD - 1.13.11.27 ko:K00457 ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100 M00044 R01372,R02521 RC00505,RC00738 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase CMS3_k127_6730859_2 1121904.ARBP01000012_gene1379 3.221e-204 649.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,47KI8@768503|Cytophagia 976|Bacteroidetes G Phosphoglucomutase phosphomannomutase alpha beta alpha domain I pgcA - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS3_k127_6730859_13 558152.IQ37_10430 2.5e-45 168.0 COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,3ZS40@59732|Chryseobacterium 976|Bacteroidetes S Protein of unknown function (DUF1572) - - - - - - - - - - - - DUF1572 CMS3_k127_6730859_6 761193.Runsl_0966 6.976e-105 350.0 COG0812@1|root,COG0812@2|Bacteria,4NE78@976|Bacteroidetes,47KJJ@768503|Cytophagia 976|Bacteroidetes M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C CMS3_k127_6730859_9 1279009.ADICEAN_01394 5.448e-84 280.0 COG2131@1|root,COG2131@2|Bacteria,4NM48@976|Bacteroidetes,47P6P@768503|Cytophagia 976|Bacteroidetes F PFAM Cytidine and deoxycytidylate deaminase zinc-binding region comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 CMS3_k127_6730859_15 1237149.C900_02479 4.634e-21 100.0 COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,47XP3@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_6730859_1 861299.J421_4478 9.173e-205 651.0 COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 CMS3_k127_6730859_12 1237149.C900_02474 4.847e-60 221.0 COG4977@1|root,COG4977@2|Bacteria,4PN3G@976|Bacteroidetes,47Y8N@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_6730859_11 1237149.C900_03290 1.085e-78 269.0 COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes,47M5I@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS3_k127_6730859_5 1237149.C900_03289 1.126e-105 347.0 COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,47N59@768503|Cytophagia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents permease component mlaE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE CMS3_k127_6730859_7 1237149.C900_03288 1.324e-96 320.0 COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,47K20@768503|Cytophagia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents, ATPase component metN - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran CMS3_k127_6758043_9 1286632.P278_00790 1.883e-41 155.0 COG3070@1|root,COG3070@2|Bacteria,4NSGZ@976|Bacteroidetes,1I4CE@117743|Flavobacteriia 976|Bacteroidetes K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N CMS3_k127_6758043_4 1408473.JHXO01000006_gene1189 1.075e-128 422.0 COG0454@1|root,COG0456@2|Bacteria,4NFWE@976|Bacteroidetes,2FNG4@200643|Bacteroidia 976|Bacteroidetes K Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_6758043_3 927658.AJUM01000034_gene121 2.115e-191 615.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,2FNK9@200643|Bacteroidia,3XJMZ@558415|Marinilabiliaceae 976|Bacteroidetes I AMP-binding enzyme fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding CMS3_k127_6758043_11 489825.LYNGBM3L_51320 3.868e-35 143.0 COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales 1117|Cyanobacteria H Belongs to the P-Pant transferase superfamily hetI GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS CMS3_k127_6758043_0 1133849.O3I_018810 0.0 2028.0 COG0604@1|root,COG3208@1|root,COG3321@1|root,COG0604@2|Bacteria,COG3208@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4FUA5@85025|Nocardiaceae 201174|Actinobacteria Q PKS_DH - - - ko:K12437 - - - - ko00000,ko01004 - - - ADH_N,ADH_zinc_N,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt CMS3_k127_6758043_13 1484460.JSWG01000015_gene948 2.897e-07 59.0 2DQ1A@1|root,32UNA@2|Bacteria,4NT2M@976|Bacteroidetes,1I4EA@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF1761 CMS3_k127_6758043_8 1338011.BD94_1918 2.374e-46 175.0 COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia 976|Bacteroidetes S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_6,UPF0227 CMS3_k127_6758043_12 1121889.AUDM01000008_gene750 6.285e-22 100.0 COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1I2P9@117743|Flavobacteriia 976|Bacteroidetes Q thioesterase paaI - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT CMS3_k127_6758043_2 1123008.KB905693_gene1405 2.601e-213 671.0 COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,2FNFV@200643|Bacteroidia,22WIN@171551|Porphyromonadaceae 976|Bacteroidetes G F5 8 type C domain protein - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc CMS3_k127_6758043_1 1237149.C900_04661 0.0 1442.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia 976|Bacteroidetes QU Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,PD40 CMS3_k127_6758043_6 1237149.C900_05578 3.457e-108 361.0 COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia 976|Bacteroidetes P Sodium/calcium exchanger protein - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex CMS3_k127_6758043_7 1279009.ADICEAN_01198 2.307e-50 192.0 COG0457@1|root,COG0457@2|Bacteria,4NJ1F@976|Bacteroidetes,47NCH@768503|Cytophagia 976|Bacteroidetes S PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 CMS3_k127_6758043_5 1124780.ANNU01000074_gene745 1.756e-128 427.0 COG3620@1|root,COG3620@2|Bacteria,4PMEJ@976|Bacteroidetes,47Y36@768503|Cytophagia 976|Bacteroidetes K IrrE N-terminal-like domain - - - ko:K07110 - - - - ko00000,ko03000 - - - HTH_19,HTH_3,Peptidase_M78 CMS3_k127_6758043_10 1189612.A33Q_1424 2.195e-35 139.0 COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia 976|Bacteroidetes L pfam nudix - - - - - - - - - - - - NUDIX CMS3_k127_6765239_6 1237149.C900_01117 6.386e-151 480.0 COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia 976|Bacteroidetes I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom CMS3_k127_6765239_5 1237149.C900_01118 1.205e-166 534.0 COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,47JDH@768503|Cytophagia 976|Bacteroidetes M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 CMS3_k127_6765239_1 1237149.C900_01121 1.067e-272 853.0 COG2885@1|root,COG2885@2|Bacteria,4NHWF@976|Bacteroidetes,47MMG@768503|Cytophagia 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_6765239_0 1237149.C900_01122 0.0 1189.0 COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,47M84@768503|Cytophagia 976|Bacteroidetes O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C CMS3_k127_6765239_3 1237149.C900_01124 1.294e-215 678.0 COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,47JSG@768503|Cytophagia 976|Bacteroidetes O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small CMS3_k127_6765239_14 1237149.C900_01127 7.712e-49 179.0 COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia 976|Bacteroidetes T PFAM Phosphoglycerate mutase sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 CMS3_k127_6765239_12 1123277.KB893239_gene1244 2.46e-62 228.0 COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia 976|Bacteroidetes M PFAM glycosyl transferase family 9 - - - - - - - - - - - - Glyco_transf_9 CMS3_k127_6765239_9 1313301.AUGC01000011_gene1165 9.039e-87 290.0 COG0463@1|root,COG0463@2|Bacteria,4NGJK@976|Bacteroidetes 976|Bacteroidetes M Protein of unknown function (DUF4254) - - - - - - - - - - - - DUF4254 CMS3_k127_6765239_8 1124780.ANNU01000008_gene2627 3.418e-97 328.0 COG0859@1|root,COG0859@2|Bacteria,4NEPH@976|Bacteroidetes,47MA4@768503|Cytophagia 976|Bacteroidetes M PFAM glycosyl transferase family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 CMS3_k127_6765239_13 1267211.KI669560_gene1791 1.845e-49 179.0 COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia 976|Bacteroidetes S EVE domain - - - - - - - - - - - - EVE CMS3_k127_6765239_15 929562.Emtol_3099 7.054e-42 173.0 28KQM@1|root,2ZA8D@2|Bacteria,4NH80@976|Bacteroidetes,47JWY@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6765239_7 1124780.ANNU01000008_gene2625 3.921e-121 406.0 28KQM@1|root,2ZA8D@2|Bacteria,4NH80@976|Bacteroidetes,47JWY@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6765239_10 1237149.C900_05853 3.005e-76 259.0 COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,47MTK@768503|Cytophagia 976|Bacteroidetes F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran CMS3_k127_6765239_4 1123057.P872_21475 3.078e-171 540.0 COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,47KS2@768503|Cytophagia 976|Bacteroidetes F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N CMS3_k127_6765239_17 929562.Emtol_3981 2.678e-05 52.0 2F8BT@1|root,340QV@2|Bacteria,4P400@976|Bacteroidetes,47VM1@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6765239_2 1121904.ARBP01000003_gene6341 4.702e-240 747.0 COG0031@1|root,COG0031@2|Bacteria,4NDZ9@976|Bacteroidetes,47K1B@768503|Cytophagia 976|Bacteroidetes E Cystathionine beta-synthase - - 4.2.1.22 ko:K01697 ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230 M00035,M00338 R00891,R01290,R04942 RC00056,RC00069,RC00256,RC00489,RC01246 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP CMS3_k127_6765239_16 926549.KI421517_gene3664 3.911e-10 67.0 2DEJT@1|root,2ZN93@2|Bacteria,4P737@976|Bacteroidetes,47X3S@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6765239_11 1237149.C900_05597 1.34e-63 223.0 COG1361@1|root,COG1361@2|Bacteria,4PKPA@976|Bacteroidetes 976|Bacteroidetes M Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA,CARDB CMS3_k127_6782610_7 1250232.JQNJ01000001_gene1914 1.589e-38 160.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR,BNR_2,Exo_endo_phos,RicinB_lectin_2,Sialidase CMS3_k127_6782610_6 504472.Slin_1887 1.53e-42 175.0 COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,47K6N@768503|Cytophagia 976|Bacteroidetes DZ Galactose oxidase, central domain nanM - - - - - - - - - - - Kelch_1,Kelch_3,Kelch_4,Kelch_6 CMS3_k127_6782610_1 1185876.BN8_00887 7.054e-204 661.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47MF5@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_6782610_4 1313421.JHBV01000016_gene5435 2.271e-67 234.0 COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes 976|Bacteroidetes S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD CMS3_k127_6782610_2 1237149.C900_01606 3.316e-200 642.0 COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,47M73@768503|Cytophagia 976|Bacteroidetes L ATP-dependent DNA helicase RecQ recQ2 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind CMS3_k127_6782610_9 929703.KE386491_gene268 4.769e-19 94.0 COG0746@1|root,COG0746@2|Bacteria,4NMYW@976|Bacteroidetes,47NQP@768503|Cytophagia 976|Bacteroidetes H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 CMS3_k127_6782610_5 880070.Cycma_4794 7.623e-54 193.0 COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes,47PU9@768503|Cytophagia 976|Bacteroidetes H MoaC family moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC CMS3_k127_6782610_3 760192.Halhy_6364 4.185e-114 380.0 COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1IQAR@117747|Sphingobacteriia 976|Bacteroidetes H MoeA N-terminal region (domain I and II) moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N CMS3_k127_6782610_0 1237149.C900_04390 7.438e-222 695.0 COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,47MYD@768503|Cytophagia 976|Bacteroidetes U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB CMS3_k127_6782610_8 1297742.A176_06197 6.272e-30 123.0 COG2346@1|root,COG2346@2|Bacteria,1Q2G1@1224|Proteobacteria,4382D@68525|delta/epsilon subdivisions,2X3CG@28221|Deltaproteobacteria,2YVEJ@29|Myxococcales 28221|Deltaproteobacteria C Bacterial-like globin - - - ko:K06886 - - - - ko00000 - - - Bac_globin CMS3_k127_6795987_5 1237149.C900_04024 1.432e-26 117.0 COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,47MWE@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Outer membrane assembly lipoprotein YfiO yfiO - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO CMS3_k127_6795987_4 643867.Ftrac_0971 2.941e-41 154.0 2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,47RC2@768503|Cytophagia 976|Bacteroidetes K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - - - - - - - - - - - RNA_pol_Rpb6 CMS3_k127_6795987_1 1237149.C900_04022 8.705e-168 535.0 COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,47MHR@768503|Cytophagia 976|Bacteroidetes H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein CMS3_k127_6795987_3 1237149.C900_04021 1.721e-102 342.0 28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,47N7V@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4835) - - - - - - - - - - - - DUF4835 CMS3_k127_6795987_2 1237149.C900_04019 2.292e-165 536.0 COG0497@1|root,COG0497@2|Bacteria,4NE3I@976|Bacteroidetes,47JTP@768503|Cytophagia 976|Bacteroidetes L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N CMS3_k127_6795987_0 313595.P700755_001953 1.825e-200 633.0 COG2271@1|root,COG2271@2|Bacteria,4PM8E@976|Bacteroidetes,1IJMM@117743|Flavobacteriia 976|Bacteroidetes G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_6803079_0 1168034.FH5T_08925 1.918e-100 340.0 COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,2FNAB@200643|Bacteroidia 976|Bacteroidetes C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A CMS3_k127_6803079_2 1237149.C900_04598 2.292e-58 206.0 COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47RT9@768503|Cytophagia 976|Bacteroidetes M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin CMS3_k127_6803079_1 643867.Ftrac_2563 1.037e-93 315.0 COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,47PPP@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 nlpD_1 - - - - - - - - - - - Peptidase_M23 CMS3_k127_6813784_4 1356852.N008_03925 8.061e-14 76.0 COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47RHW@768503|Cytophagia 976|Bacteroidetes M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_6813784_1 1237149.C900_02878 2.12e-145 503.0 COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes,47S64@768503|Cytophagia 976|Bacteroidetes S PKD domain - - - - - - - - - - - - PKD CMS3_k127_6813784_3 1237149.C900_02880 8.372e-51 185.0 COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,47QMM@768503|Cytophagia 976|Bacteroidetes F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran CMS3_k127_6813784_2 1237149.C900_02882 8.986e-143 456.0 COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,47K8P@768503|Cytophagia 976|Bacteroidetes H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf CMS3_k127_6813784_0 313606.M23134_03634 2.155e-200 628.0 COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,47NMD@768503|Cytophagia 976|Bacteroidetes C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS3_k127_6838858_12 1122176.KB903534_gene2185 4.509e-29 124.0 COG1595@1|root,COG1595@2|Bacteria,4NMK4@976|Bacteroidetes,1ISCY@117747|Sphingobacteriia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6838858_2 1237149.C900_01855 1.148e-127 411.0 COG1398@1|root,COG1398@2|Bacteria,4NE0I@976|Bacteroidetes,47KJ0@768503|Cytophagia 976|Bacteroidetes I fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS3_k127_6838858_11 1121875.KB907546_gene2671 3.27e-42 158.0 COG2010@1|root,COG2010@2|Bacteria,4NV2A@976|Bacteroidetes,1I5FJ@117743|Flavobacteriia 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_6838858_15 335543.Sfum_0443 0.0007508 51.0 COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria,42VJ7@68525|delta/epsilon subdivisions,2WS0Z@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Ethylbenzene dehydrogenase - - - - - - - - - - - - EB_dh CMS3_k127_6838858_14 1168034.FH5T_16970 9.939e-17 84.0 COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - PSCyt1 CMS3_k127_6838858_6 313603.FB2170_12601 3.403e-64 230.0 COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1I0TY@117743|Flavobacteriia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - CMS3_k127_6838858_1 929556.Solca_2233 9.205e-145 465.0 COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S dicluster domain - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11 CMS3_k127_6838858_0 929556.Solca_2234 1.106e-197 624.0 COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,1INKZ@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD CMS3_k127_6838858_7 929556.Solca_2235 4.921e-51 192.0 2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6838858_9 1237149.C900_03415 1.791e-45 169.0 COG0454@1|root,COG0456@2|Bacteria,4NTYJ@976|Bacteroidetes,47VJU@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 CMS3_k127_6838858_8 1313421.JHBV01000019_gene5357 2.794e-46 173.0 COG1595@1|root,COG1595@2|Bacteria,4NU6U@976|Bacteroidetes,1J0AR@117747|Sphingobacteriia 976|Bacteroidetes K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6838858_4 1123277.KB893243_gene301 5.542e-90 303.0 COG0500@1|root,COG2226@2|Bacteria,4NEUC@976|Bacteroidetes,47MVN@768503|Cytophagia 976|Bacteroidetes Q Hypothetical methyltransferase - - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_31 CMS3_k127_6838858_3 643867.Ftrac_2999 3.801e-105 361.0 COG3188@1|root,COG3188@2|Bacteria,4NHCJ@976|Bacteroidetes,47K9Y@768503|Cytophagia 976|Bacteroidetes NU usher protein - - - - - - - - - - - - - CMS3_k127_6838858_5 1122176.KB903570_gene4810 2.717e-73 263.0 COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia 976|Bacteroidetes E Aminotransferase class-V - - 5.1.1.17 ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 M00673 R04147 RC00302 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 CMS3_k127_6838858_10 1189612.A33Q_1181 1.011e-42 170.0 28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - BetR CMS3_k127_6838858_13 1392498.JQLH01000001_gene1828 1.278e-28 116.0 COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia,2PHFP@252356|Maribacter 976|Bacteroidetes S SRPBCC domain-containing protein - - - - - - - - - - - - Polyketide_cyc CMS3_k127_6840589_31 1237149.C900_01140 2.273e-11 66.0 28NIY@1|root,2ZBK8@2|Bacteria,4NM7G@976|Bacteroidetes,47PEJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6840589_5 1124780.ANNU01000043_gene346 1.426e-190 598.0 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,47K6D@768503|Cytophagia 976|Bacteroidetes L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA CMS3_k127_6840589_8 1237149.C900_01138 1.398e-156 504.0 COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,47J9P@768503|Cytophagia 976|Bacteroidetes V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6840589_6 153721.MYP_88 3.483e-188 592.0 COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,47J9B@768503|Cytophagia 976|Bacteroidetes J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth CMS3_k127_6840589_18 1237149.C900_01135 4.761e-66 232.0 COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,47P6K@768503|Cytophagia 976|Bacteroidetes I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD CMS3_k127_6840589_23 1123276.KB893246_gene817 3.552e-43 157.0 2C8VT@1|root,32RN1@2|Bacteria,4NS78@976|Bacteroidetes,47R0I@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2795) - - - - - - - - - - - - DUF2795 CMS3_k127_6840589_1 1288963.ADIS_3742 2.574e-303 937.0 COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47M5V@768503|Cytophagia 976|Bacteroidetes S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn CMS3_k127_6840589_24 1158294.JOMI01000001_gene1995 2.254e-42 173.0 COG0793@1|root,COG0793@2|Bacteria,4NJAA@976|Bacteroidetes,2FVB8@200643|Bacteroidia 976|Bacteroidetes M Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 CMS3_k127_6840589_10 313606.M23134_05263 6.762e-122 398.0 28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,47JAX@768503|Cytophagia 976|Bacteroidetes S S1 P1 nuclease - - - - - - - - - - - - S1-P1_nuclease,Zn_dep_PLPC CMS3_k127_6840589_29 1356852.N008_04290 8.757e-24 102.0 COG0268@1|root,COG0268@2|Bacteria,4NSB1@976|Bacteroidetes,47R98@768503|Cytophagia 976|Bacteroidetes J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p CMS3_k127_6840589_14 153721.MYP_81 8.797e-103 339.0 COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,47KTY@768503|Cytophagia 976|Bacteroidetes E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC CMS3_k127_6840589_21 1237149.C900_04988 2.799e-53 194.0 COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 CMS3_k127_6840589_0 1237149.C900_04990 2.954e-315 983.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,47JAK@768503|Cytophagia 976|Bacteroidetes J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind CMS3_k127_6840589_28 1237149.C900_04991 2.608e-24 104.0 2DSW7@1|root,33HNN@2|Bacteria,4NY8S@976|Bacteroidetes,47SU0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6840589_27 1237149.C900_04992 2.342e-29 119.0 COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,47S0D@768503|Cytophagia 976|Bacteroidetes D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA CMS3_k127_6840589_2 1237149.C900_04994 2.219e-247 772.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,47KJE@768503|Cytophagia 976|Bacteroidetes S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 CMS3_k127_6840589_13 1336803.PHEL49_1500 3.221e-105 352.0 COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,1HWY9@117743|Flavobacteriia,3VXD5@52959|Polaribacter 976|Bacteroidetes S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 CMS3_k127_6840589_20 1278073.MYSTI_05664 4.924e-54 209.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Aminotran_5,DUF4377,Lactamase_B,Rhodanese CMS3_k127_6840589_15 1122176.KB903587_gene4434 7.734e-81 279.0 COG4242@1|root,COG4242@2|Bacteria,4NHDE@976|Bacteroidetes,1IWDD@117747|Sphingobacteriia 976|Bacteroidetes PQ Peptidase family S51 - - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 CMS3_k127_6840589_12 760192.Halhy_3768 2.79e-107 353.0 28HGK@1|root,2Z7SE@2|Bacteria,4NGDR@976|Bacteroidetes 976|Bacteroidetes S Malonate/sodium symporter MadM subunit - - - - - - - - - - - - MadM CMS3_k127_6840589_25 929562.Emtol_0620 2.165e-38 147.0 2CAQ0@1|root,32RRS@2|Bacteria,4NRRH@976|Bacteroidetes,47QP4@768503|Cytophagia 976|Bacteroidetes S Malonate transporter MadL subunit - - - - - - - - - - - - MadL CMS3_k127_6840589_4 388413.ALPR1_10630 1.362e-191 609.0 COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47NTH@768503|Cytophagia 976|Bacteroidetes IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897,ko:K18660 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C,PP-binding CMS3_k127_6840589_3 1237149.C900_01475 2.631e-197 634.0 COG0642@1|root,COG2205@2|Bacteria,4NN26@976|Bacteroidetes 976|Bacteroidetes T 7TM diverse intracellular signalling - - - - - - - - - - - - 7TMR-DISM_7TM,HATPase_c,HisKA CMS3_k127_6840589_22 1237149.C900_01479 1.462e-45 168.0 COG0745@1|root,COG0745@2|Bacteria 1237149.C900_01479|- T phosphorelay signal transduction system - - - - - - - - - - - - - CMS3_k127_6840589_7 313606.M23134_01687 2.086e-160 511.0 COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,47NGE@768503|Cytophagia 976|Bacteroidetes S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C CMS3_k127_6840589_30 866536.Belba_2876 1.087e-14 75.0 2EK70@1|root,33DXD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_6840589_26 1237149.C900_04165 3.319e-33 132.0 COG1186@1|root,COG1186@2|Bacteria,4NQ41@976|Bacteroidetes,47R30@768503|Cytophagia 976|Bacteroidetes J RF-1 domain arfB - - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 CMS3_k127_6840589_9 643867.Ftrac_0478 1.863e-146 474.0 COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47MUM@768503|Cytophagia 976|Bacteroidetes P PFAM natural resistance-associated macrophage protein mntH - - - - - - - - - - - Nramp CMS3_k127_6840589_16 1313421.JHBV01000142_gene1108 3.97e-76 263.0 COG1540@1|root,COG1540@2|Bacteria,4NJ86@976|Bacteroidetes,1IP2K@117747|Sphingobacteriia 976|Bacteroidetes S Belongs to the UPF0271 (lamB) family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF CMS3_k127_6840589_19 1313421.JHBV01000142_gene1109 5.553e-58 209.0 COG2049@1|root,COG2049@2|Bacteria,4NMNT@976|Bacteroidetes,1ISIZ@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D CMS3_k127_6840589_17 1313421.JHBV01000142_gene1110 1.353e-75 265.0 COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,1IQAT@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Allophanate hydrolase subunit 2 - - - ko:K06350 - - - - ko00000 - - - CT_A_B CMS3_k127_6840589_11 1237149.C900_01494 3.629e-108 360.0 COG0577@1|root,COG0577@2|Bacteria,4NDW7@976|Bacteroidetes,47N35@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_6859031_10 1121957.ATVL01000007_gene2306 3.739e-30 121.0 COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,47JMA@768503|Cytophagia 976|Bacteroidetes EH Anthranilate synthase component I, N terminal region trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind CMS3_k127_6859031_7 926556.Echvi_2506 2.961e-68 237.0 COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,47JZQ@768503|Cytophagia 976|Bacteroidetes EH TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase pabA - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase CMS3_k127_6859031_3 1124780.ANNU01000065_gene465 5.859e-132 428.0 COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,47KKR@768503|Cytophagia 976|Bacteroidetes E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 CMS3_k127_6859031_5 1237149.C900_03302 4.615e-96 321.0 COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,47JRX@768503|Cytophagia 976|Bacteroidetes E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS CMS3_k127_6859031_8 1137281.D778_00253 4.897e-45 170.0 COG0135@1|root,COG0135@2|Bacteria,4NNQ1@976|Bacteroidetes,1I1CD@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI CMS3_k127_6859031_1 1124780.ANNU01000065_gene468 5.347e-176 561.0 COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,47KSV@768503|Cytophagia 976|Bacteroidetes E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS3_k127_6859031_6 926549.KI421517_gene3921 1.153e-84 288.0 COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,47JYN@768503|Cytophagia 976|Bacteroidetes E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA CMS3_k127_6859031_2 1237149.C900_03306 1.51e-155 497.0 COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,47KY7@768503|Cytophagia 976|Bacteroidetes E PFAM DAHP synthetase I family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 CMS3_k127_6859031_0 1237149.C900_02391 0.0 1622.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47P32@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_6859031_4 1237149.C900_02392 1.203e-97 325.0 COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47RIH@768503|Cytophagia 976|Bacteroidetes M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - DUF4292,LolA_like CMS3_k127_6859031_9 1333998.M2A_1149 1.296e-40 154.0 COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,4BQUK@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S YHS domain - - - - - - - - - - - - YHS CMS3_k127_6861215_6 1519464.HY22_03925 5.9e-23 105.0 COG0622@1|root,COG0622@2|Bacteria,1FFF7@1090|Chlorobi 1090|Chlorobi S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_6861215_3 869210.Marky_0877 1.04e-73 257.0 COG0697@1|root,COG0697@2|Bacteria,1WI4X@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EG PFAM EamA-like transporter family - - - - - - - - - - - - EamA CMS3_k127_6861215_1 563040.Saut_0247 6.68e-136 440.0 COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2YM8B@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C CMS3_k127_6861215_2 1124780.ANNU01000050_gene2107 8.995e-100 336.0 COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia 976|Bacteroidetes S Rhodanese Homology Domain - - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese CMS3_k127_6861215_4 1121912.AUHD01000007_gene503 2.893e-67 237.0 COG0266@1|root,COG0266@2|Bacteria,4NFM2@976|Bacteroidetes,1HYNY@117743|Flavobacteriia 976|Bacteroidetes L Formamidopyrimidine-DNA glycosylase N-terminal domain mutM - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS CMS3_k127_6861215_5 886377.Murru_0701 6.443e-30 123.0 COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1I3Q8@117743|Flavobacteriia 976|Bacteroidetes S Cupin domain - - - - - - - - - - - - Cupin_2 CMS3_k127_6861215_0 1237149.C900_05833 1.956e-217 699.0 COG4775@1|root,COG4775@2|Bacteria,4NDYT@976|Bacteroidetes,47MA1@768503|Cytophagia 976|Bacteroidetes M CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_6906585_0 643867.Ftrac_3687 0.0 1233.0 COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain nrfC - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molydop_binding CMS3_k127_6906585_2 1237149.C900_03265 3.059e-268 829.0 COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia 976|Bacteroidetes C PFAM Polysulphide reductase, NrfD nrfD - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD CMS3_k127_6906585_8 1237149.C900_03266 6.211e-77 261.0 COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,47K4U@768503|Cytophagia 976|Bacteroidetes C Quinol cytochrome c oxidoreductase membrane protein actD - - - - - - - - - - - DUF3341 CMS3_k127_6906585_7 1237149.C900_03267 5.178e-77 262.0 COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,47PEX@768503|Cytophagia 976|Bacteroidetes C PFAM Cytochrome C actE - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_6906585_3 1237149.C900_03268 1.557e-172 552.0 COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,47JUF@768503|Cytophagia 976|Bacteroidetes P Quinol cytochrome c oxidoreductase actF - - - - - - - - - - - - CMS3_k127_6906585_4 388413.ALPR1_06610 7.203e-133 432.0 COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,47JF8@768503|Cytophagia 976|Bacteroidetes C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM CMS3_k127_6906585_1 1237149.C900_03270 0.0 1086.0 COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,47JBQ@768503|Cytophagia 976|Bacteroidetes C Belongs to the heme-copper respiratory oxidase family coxN - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 CMS3_k127_6906585_6 643867.Ftrac_3694 2.646e-93 317.0 COG1612@1|root,COG1612@2|Bacteria,4NEBR@976|Bacteroidetes,47JI1@768503|Cytophagia 976|Bacteroidetes O Cytochrome oxidase assembly protein ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA CMS3_k127_6906585_5 1124780.ANNU01000003_gene1428 2.287e-119 390.0 COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,47MB0@768503|Cytophagia 976|Bacteroidetes O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA CMS3_k127_6906585_10 504472.Slin_5674 3.967e-63 222.0 COG1845@1|root,COG1845@2|Bacteria,4NFA7@976|Bacteroidetes,47NS2@768503|Cytophagia 976|Bacteroidetes C PFAM cytochrome c oxidase subunit III ctaE - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 CMS3_k127_6906585_9 643867.Ftrac_3697 2.731e-75 256.0 COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,47JVP@768503|Cytophagia 976|Bacteroidetes C cytochrome c oxidase subunit III coxP - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 CMS3_k127_6913079_14 1047013.AQSP01000048_gene2216 2.286e-14 83.0 COG3279@1|root,COG3279@2|Bacteria,2NRAD@2323|unclassified Bacteria 2|Bacteria KT LytTr DNA-binding domain coxC GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K02477,ko:K07705,ko:K21696 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022,ko03000 - - - LytTR,MHYT,Response_reg CMS3_k127_6913079_5 1237149.C900_00841 6.972e-146 492.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_6913079_0 1237149.C900_00620 1.555e-274 861.0 COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,47KIQ@768503|Cytophagia 976|Bacteroidetes G Trehalose-phosphatase otsB - 2.4.1.15,3.1.3.12 ko:K16055 ko00500,ko01100,map00500,map01100 - R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20,Trehalose_PPase CMS3_k127_6913079_1 1121957.ATVL01000009_gene1105 1.871e-264 826.0 COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,47MRU@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolases family 15 - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glyco_hydro_15 CMS3_k127_6913079_13 946077.W5A_00300 1.178e-30 128.0 COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1HWWN@117743|Flavobacteriia 976|Bacteroidetes S Phosphohydrolase - - - - - - - - - - - - HD CMS3_k127_6913079_11 1121904.ARBP01000012_gene1244 3.212e-64 232.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6913079_12 1328313.DS2_13319 9.934e-45 169.0 COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,1RYIU@1236|Gammaproteobacteria,4694J@72275|Alteromonadaceae 1236|Gammaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - FHA,Guanylate_cyc CMS3_k127_6913079_2 1123057.P872_22585 9.72e-255 814.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47N3A@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6913079_9 1121904.ARBP01000017_gene5095 1.554e-91 314.0 COG0457@1|root,COG0457@2|Bacteria 1121904.ARBP01000017_gene5095|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - CMS3_k127_6913079_7 1237149.C900_03643 3.903e-112 372.0 COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,47PJS@768503|Cytophagia 976|Bacteroidetes M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel CMS3_k127_6913079_3 1237149.C900_04734 2.482e-183 586.0 COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,47MJK@768503|Cytophagia 976|Bacteroidetes M glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_6913079_6 1189612.A33Q_3630 5.579e-141 455.0 COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,47KUF@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3641) - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM CMS3_k127_6913079_4 1121904.ARBP01000053_gene480 4.846e-148 482.0 COG0833@1|root,COG0833@2|Bacteria,4PPC8@976|Bacteroidetes 976|Bacteroidetes E Amino acid permease - - - ko:K11733 - - - - ko00000,ko02000 2.A.3.1.2 - - AA_permease CMS3_k127_6913079_10 696281.Desru_2841 9.017e-82 292.0 COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,24AKB@186801|Clostridia,260D3@186807|Peptococcaceae 186801|Clostridia C Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - 1.2.7.8 ko:K00179 - - - - br01601,ko00000,ko01000 - - - Fer4,POR_N,TPP_enzyme_C CMS3_k127_6913079_8 1121346.KB899816_gene3328 4.097e-100 332.0 COG5285@1|root,COG5285@2|Bacteria,1VU1E@1239|Firmicutes,4HU97@91061|Bacilli,26T5V@186822|Paenibacillaceae 91061|Bacilli Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH CMS3_k127_6913079_15 1296415.JACC01000039_gene3987 1.69e-12 78.0 COG2207@1|root,COG2207@2|Bacteria,4NTTN@976|Bacteroidetes,1IKV5@117743|Flavobacteriia,2YH87@290174|Aquimarina 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_6933333_1 1237149.C900_03604 3.298e-91 308.0 COG2067@1|root,COG2067@2|Bacteria,4NVCH@976|Bacteroidetes,47SCX@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - OMP_b-brl CMS3_k127_6933333_0 1048983.EL17_17865 1.638e-178 577.0 COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,47KE5@768503|Cytophagia 976|Bacteroidetes GM Polysaccharide biosynthesis protein - - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 CMS3_k127_6960611_1 1237149.C900_04617 1.214e-94 316.0 COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PM5K@976|Bacteroidetes,47MDR@768503|Cytophagia 976|Bacteroidetes M Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - HEAT,HEAT_2,Pro_isomerase CMS3_k127_6960611_0 1237149.C900_04618 3.644e-152 489.0 COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia 976|Bacteroidetes F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp CMS3_k127_6960611_3 1237149.C900_04619 5.578e-66 229.0 COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,47PQS@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC CMS3_k127_6960611_2 313606.M23134_06681 7.298e-69 239.0 COG0431@1|root,COG0431@2|Bacteria,4NN31@976|Bacteroidetes,47SD0@768503|Cytophagia 976|Bacteroidetes S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red CMS3_k127_6969038_7 1237149.C900_03404 1.634e-66 234.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2 CMS3_k127_6969038_6 313595.P700755_001359 2.733e-68 237.0 COG2094@1|root,COG2094@2|Bacteria,4NP22@976|Bacteroidetes,1I1TP@117743|Flavobacteriia,4C30E@83612|Psychroflexus 976|Bacteroidetes L Methylpurine-DNA glycosylase (MPG) mpg - 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco CMS3_k127_6969038_9 313606.M23134_02896 4.781e-63 229.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_6969038_10 1047013.AQSP01000133_gene2140 3.29e-39 153.0 COG3254@1|root,COG3254@2|Bacteria,2NRFN@2323|unclassified Bacteria 2|Bacteria S L-rhamnose mutarotase - - 5.1.3.32 ko:K03534 - - R10819 RC00563 ko00000,ko01000 - - - rhaM CMS3_k127_6969038_5 742767.HMPREF9456_01748 1.497e-141 458.0 COG0615@1|root,COG2605@1|root,COG0615@2|Bacteria,COG2605@2|Bacteria,4NGSD@976|Bacteroidetes,2FQ1X@200643|Bacteroidia,22WKK@171551|Porphyromonadaceae 976|Bacteroidetes IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like,GHMP_kinases_C CMS3_k127_6969038_3 1191523.MROS_1588 9.762e-172 548.0 COG0738@1|root,COG0738@2|Bacteria 2|Bacteria G Major facilitator superfamily fucP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 CMS3_k127_6969038_8 1121373.KB903625_gene3144 1.218e-65 234.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_6969038_1 1124780.ANNU01000002_gene1612 7.141e-222 702.0 COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yidK - - - - - - - - - - - SSF CMS3_k127_6969038_0 1237149.C900_04147 1.182e-303 953.0 COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia 976|Bacteroidetes G PFAM GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L CMS3_k127_6969038_2 1120968.AUBX01000018_gene2072 3.683e-219 691.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia 976|Bacteroidetes Q PFAM D-aminoacylase, C-terminal region - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 CMS3_k127_6969038_4 861299.J421_6092 6.481e-144 471.0 COG1680@1|root,COG1680@2|Bacteria,1ZUKR@142182|Gemmatimonadetes 142182|Gemmatimonadetes V Domain of unknown function (DUF3471) - - - - - - - - - - - - Beta-lactamase,DUF3471 CMS3_k127_698004_0 1121875.KB907548_gene1622 2.552e-158 522.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,HTH_18,TPR_8 CMS3_k127_698004_3 1121875.KB907553_gene24 4.506e-38 164.0 COG0412@1|root,COG1262@1|root,COG2114@1|root,COG0412@2|Bacteria,COG1262@2|Bacteria,COG2114@2|Bacteria,4PPKM@976|Bacteroidetes 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc CMS3_k127_698004_4 43989.cce_0003 1.207e-05 49.0 2EH9Q@1|root,33B1J@2|Bacteria,1GAX5@1117|Cyanobacteria,3KIS1@43988|Cyanothece 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_698004_2 1123035.ARLA01000017_gene8 1.321e-59 214.0 COG1357@1|root,COG1357@2|Bacteria,4NR89@976|Bacteroidetes,1I76A@117743|Flavobacteriia 976|Bacteroidetes S Pentapeptide repeats (9 copies) - - - - - - - - - - - - Pentapeptide_3 CMS3_k127_698004_1 760192.Halhy_5818 3.101e-85 291.0 COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C CMS3_k127_7000841_2 313606.M23134_04794 1.1e-322 1015.0 COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Plug,TonB_dep_Rec CMS3_k127_7000841_29 926549.KI421517_gene1183 1.218e-39 148.0 COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,47R69@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 CMS3_k127_7000841_27 643867.Ftrac_1817 4.859e-41 154.0 COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,47R7R@768503|Cytophagia 976|Bacteroidetes J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - HHH_5,Rho_N,Ribosomal_L21p CMS3_k127_7000841_10 452471.Aasi_0535 6.837e-185 581.0 COG0208@1|root,COG0208@2|Bacteria,4NG18@976|Bacteroidetes,47MSG@768503|Cytophagia 976|Bacteroidetes F reductase, small chain nrdB - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm CMS3_k127_7000841_0 1237149.C900_02809 0.0 1382.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes,47JEH@768503|Cytophagia 976|Bacteroidetes F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdA - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN CMS3_k127_7000841_18 313606.M23134_01828 2.99e-92 321.0 COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NI5R@976|Bacteroidetes,47QJA@768503|Cytophagia 976|Bacteroidetes T GHKL domain - - - - - - - - - - - - 4HB_MCP_1,CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_9 CMS3_k127_7000841_24 1124780.ANNU01000005_gene2453 3.397e-65 229.0 COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,47N8U@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_7000841_16 929703.KE386491_gene2688 7.192e-100 334.0 COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,47JRS@768503|Cytophagia 976|Bacteroidetes H Belongs to the FPP GGPP synthase family idsA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt CMS3_k127_7000841_6 1120965.AUBV01000016_gene108 2.966e-269 846.0 COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,47JK7@768503|Cytophagia 976|Bacteroidetes J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573,ko:K12585 ko03018,map03018 M00391 - - ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 CMS3_k127_7000841_21 929703.KE386491_gene3167 1.303e-84 286.0 COG0417@1|root,COG0417@2|Bacteria,4PKQ5@976|Bacteroidetes,47KCR@768503|Cytophagia 976|Bacteroidetes L 3'-5' exonuclease related to the exonuclease domain of PolB - - - ko:K07501 - - - - ko00000 - - - DNA_pol_B_exo2 CMS3_k127_7000841_15 1120968.AUBX01000011_gene3325 4.243e-108 355.0 COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia 976|Bacteroidetes H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB CMS3_k127_7000841_17 926549.KI421517_gene2288 2.327e-97 327.0 COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,47K7F@768503|Cytophagia 976|Bacteroidetes G Phosphomannose isomerase type I manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - - PMI_typeI CMS3_k127_7000841_7 926549.KI421517_gene2289 1.622e-217 689.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,47JID@768503|Cytophagia 976|Bacteroidetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI CMS3_k127_7000841_36 1237149.C900_02111 1.207e-25 109.0 COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,47QW9@768503|Cytophagia 976|Bacteroidetes L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 CMS3_k127_7000841_19 1237149.C900_01531 1.189e-88 301.0 COG2849@1|root,COG2849@2|Bacteria,4NK1X@976|Bacteroidetes,47NFY@768503|Cytophagia 976|Bacteroidetes S repeat protein - - - - - - - - - - - - - CMS3_k127_7000841_3 1237149.C900_03488 5.737e-312 964.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,47JAZ@768503|Cytophagia 976|Bacteroidetes O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c_3,HSP90 CMS3_k127_7000841_32 643867.Ftrac_3458 7.439e-35 138.0 2AVDM@1|root,31M58@2|Bacteria,4P9SJ@976|Bacteroidetes,47RZW@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4293) - - - - - - - - - - - - DUF4293 CMS3_k127_7000841_9 1237149.C900_03485 2.303e-197 621.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JXM@768503|Cytophagia 976|Bacteroidetes I Belongs to the thiolase family - - 2.3.1.174,2.3.1.9 ko:K00626,ko:K07823 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R00829,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS3_k127_7000841_23 1237149.C900_03483 3.211e-70 245.0 COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,47KUM@768503|Cytophagia 976|Bacteroidetes J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 CMS3_k127_7000841_4 1237149.C900_03482 1.808e-274 854.0 COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,47JVG@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran CMS3_k127_7000841_37 1121904.ARBP01000017_gene5134 9.893e-25 107.0 COG1695@1|root,COG1695@2|Bacteria,4P6G7@976|Bacteroidetes,47VZ7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_7000841_13 1047013.AQSP01000095_gene2303 2.728e-151 511.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7000841_33 504472.Slin_4697 5.799e-32 131.0 COG0607@1|root,COG1996@1|root,COG0607@2|Bacteria,COG1996@2|Bacteria,4PIDM@976|Bacteroidetes,47X19@768503|Cytophagia 976|Bacteroidetes P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese CMS3_k127_7000841_5 1237149.C900_03476 3.964e-273 851.0 COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran CMS3_k127_7000841_12 1237149.C900_03474 4.765e-159 509.0 COG0334@1|root,COG0334@2|Bacteria,4NF3I@976|Bacteroidetes,47MHP@768503|Cytophagia 976|Bacteroidetes E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N CMS3_k127_7000841_20 1237149.C900_03473 2.177e-87 301.0 COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,47M4A@768503|Cytophagia 976|Bacteroidetes K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB CMS3_k127_7000841_30 1237149.C900_03472 1.552e-35 137.0 COG4980@1|root,COG4980@2|Bacteria,4NVHP@976|Bacteroidetes,47RXK@768503|Cytophagia 976|Bacteroidetes S YtxH-like protein - - - - - - - - - - - - YtxH CMS3_k127_7000841_25 1237149.C900_03471 1.302e-51 189.0 2CG1Y@1|root,31EK1@2|Bacteria,4NUTU@976|Bacteroidetes,47XYM@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 CMS3_k127_7000841_31 1237149.C900_03470 5.654e-35 138.0 COG1862@1|root,COG1862@2|Bacteria,4NUT4@976|Bacteroidetes,47R3A@768503|Cytophagia 976|Bacteroidetes U TIGRFAM preprotein translocase, YajC subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC CMS3_k127_7000841_22 1124780.ANNU01000018_gene1652 1.189e-72 256.0 COG4856@1|root,COG4856@2|Bacteria,4NK5K@976|Bacteroidetes,47K4N@768503|Cytophagia 976|Bacteroidetes S YbbR-like protein - - - - - - - - - - - - - CMS3_k127_7000841_26 1288963.ADIS_0655 9.787e-46 172.0 COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,47P6S@768503|Cytophagia 976|Bacteroidetes H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE CMS3_k127_7000841_38 1120966.AUBU01000012_gene188 1.11e-23 103.0 2EDEU@1|root,337B5@2|Bacteria,4NVH5@976|Bacteroidetes,47SHQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7000841_8 1237149.C900_01785 1.063e-202 638.0 COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia 976|Bacteroidetes F TIGRFAM dihydroorotase, multifunctional complex type pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 CMS3_k127_7000841_11 1279009.ADICEAN_01735 1.408e-173 558.0 COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 CMS3_k127_7000841_1 1237149.C900_01776 0.0 1360.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,47K29@768503|Cytophagia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P CMS3_k127_7000841_35 1239962.C943_01996 3.175e-27 115.0 COG1393@1|root,COG1393@2|Bacteria,4NXD1@976|Bacteroidetes,47SWP@768503|Cytophagia 976|Bacteroidetes P ArsC family - - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC CMS3_k127_7000841_34 504472.Slin_1759 2.989e-29 121.0 COG1695@1|root,COG1695@2|Bacteria,4P3EW@976|Bacteroidetes,47V29@768503|Cytophagia 976|Bacteroidetes K PFAM transcriptional regulator PadR family protein - - - - - - - - - - - - PadR CMS3_k127_7000841_14 471854.Dfer_4857 2.939e-145 492.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7001076_0 1123073.KB899243_gene684 7.282e-22 112.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales 135614|Xanthomonadales T Adenylate cyclase - - - - - - - - - - - - TPR_8 CMS3_k127_7001076_1 746697.Aeqsu_2760 1.98e-07 64.0 2BTQM@1|root,32NXS@2|Bacteria,4PFK3@976|Bacteroidetes,1I7AQ@117743|Flavobacteriia 976|Bacteroidetes S TIR domain - - - - - - - - - - - - TIR_2 CMS3_k127_7002774_0 926549.KI421517_gene2647 2.197e-121 409.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_7002774_1 1121374.KB891589_gene45 3.239e-108 364.0 COG0733@1|root,COG0733@2|Bacteria,1NQUA@1224|Proteobacteria,1SN07@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Sodium:neurotransmitter symporter family - - - - - - - - - - - - SNF CMS3_k127_7002774_4 1122221.JHVI01000007_gene2170 2.133e-51 186.0 COG4101@1|root,COG4101@2|Bacteria 2|Bacteria G 3-hydroxyanthranilate 3,4-dioxygenase activity - - - - - - - - - - - - Cupin_2 CMS3_k127_7002774_5 761193.Runsl_5485 3.564e-28 119.0 2A8XY@1|root,30Y1J@2|Bacteria,4NZRD@976|Bacteroidetes,47W74@768503|Cytophagia 976|Bacteroidetes C Photosynthetic reaction centre cytochrome C subunit - - - - - - - - - - - - CytoC_RC CMS3_k127_7002774_3 643867.Ftrac_2134 1.07e-70 251.0 COG0457@1|root,COG0457@2|Bacteria,4NGID@976|Bacteroidetes,47PKP@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_7002774_2 1313421.JHBV01000012_gene4088 6.174e-83 284.0 COG0644@1|root,COG0644@2|Bacteria 2|Bacteria C geranylgeranyl reductase activity - - - - - - - - - - - - FAD_binding_3,Lycopene_cycl,Trp_halogenase CMS3_k127_7043300_2 1124780.ANNU01000015_gene2053 1.371e-71 250.0 COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,47JQR@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA CMS3_k127_7043300_0 1237149.C900_00907 2.399e-125 409.0 COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia 976|Bacteroidetes E PFAM peptidase T2 asparaginase 2 - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 CMS3_k127_7043300_1 1408433.JHXV01000022_gene3168 3.476e-93 315.0 COG1524@1|root,COG1524@2|Bacteria,4PKSD@976|Bacteroidetes,1IJEH@117743|Flavobacteriia 976|Bacteroidetes S Metalloenzyme superfamily - - - - - - - - - - - - Metalloenzyme,Phosphodiest CMS3_k127_7054296_4 1239962.C943_00710 1.112e-42 162.0 COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,47P7G@768503|Cytophagia 976|Bacteroidetes Q membrane - - - - - - - - - - - - - CMS3_k127_7054296_1 1469557.JSWF01000033_gene1651 8.716e-157 502.0 COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1HYD2@117743|Flavobacteriia 976|Bacteroidetes P Belongs to the alkaline phosphatase family - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase CMS3_k127_7054296_3 1121481.AUAS01000023_gene5251 1.604e-127 439.0 COG1629@1|root,COG2373@1|root,COG1629@2|Bacteria,COG2373@2|Bacteria,4NG2S@976|Bacteroidetes,47K94@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - A2M,A2M_N,A2M_comp,A2M_recep,Plug,Thiol-ester_cl CMS3_k127_7054296_0 504472.Slin_3267 1.275e-306 956.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia 976|Bacteroidetes EU Dienelactone hydrolase family - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 CMS3_k127_7054296_6 1048983.EL17_22660 1.102e-22 105.0 COG2353@1|root,COG2353@2|Bacteria,4NTB0@976|Bacteroidetes,47VJ0@768503|Cytophagia 976|Bacteroidetes S Pfam YceI-like domain - - - - - - - - - - - - YceI CMS3_k127_7054296_2 1288963.ADIS_2413 1.897e-155 501.0 2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,47N8C@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7054296_5 1347342.BN863_11430 7.21e-42 160.0 COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1I2Z5@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_7078558_0 1237149.C900_05937 1.224e-172 552.0 COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,47KF7@768503|Cytophagia 976|Bacteroidetes U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas CMS3_k127_7078558_6 714943.Mucpa_3902 1.174e-80 274.0 COG2220@1|root,COG2220@2|Bacteria,4NGD5@976|Bacteroidetes,1IRXP@117747|Sphingobacteriia 976|Bacteroidetes S Belongs to the UPF0173 family - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 CMS3_k127_7078558_2 643867.Ftrac_3755 3.284e-128 413.0 COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,47JM3@768503|Cytophagia 976|Bacteroidetes D PFAM CobQ CobB MinD ParA nucleotide binding domain soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 CMS3_k127_7078558_3 926549.KI421517_gene3826 4.02e-103 343.0 COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,47K9I@768503|Cytophagia 976|Bacteroidetes K Belongs to the ParB family parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc CMS3_k127_7078558_11 1250232.JQNJ01000001_gene133 8.191e-28 119.0 28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes,1I18T@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7078558_7 643867.Ftrac_3752 1.643e-76 263.0 COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,47KG4@768503|Cytophagia 976|Bacteroidetes E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N CMS3_k127_7078558_1 1237149.C900_05943 2.061e-160 512.0 COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,47JH7@768503|Cytophagia 976|Bacteroidetes U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 CMS3_k127_7078558_4 1124780.ANNU01000037_gene125 2.061e-102 336.0 COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,47JRB@768503|Cytophagia 976|Bacteroidetes L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CMS3_k127_7078558_10 1279009.ADICEAN_02729 4.026e-59 207.0 COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,47PP3@768503|Cytophagia 976|Bacteroidetes P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 CMS3_k127_7078558_9 1124780.ANNU01000037_gene123 1.391e-66 235.0 COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,47N8Y@768503|Cytophagia 976|Bacteroidetes S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 CMS3_k127_7078558_8 153721.MYP_2343 1.966e-73 252.0 COG0500@1|root,COG0500@2|Bacteria,4NNNE@976|Bacteroidetes,47Q1Z@768503|Cytophagia 976|Bacteroidetes Q Thiopurine S-methyltransferase (TPMT) tpm - 2.1.1.67 ko:K00569 ko00983,map00983 - R08236,R08239,R08246 RC00003,RC00980,RC02277 ko00000,ko00001,ko01000 - - - TPMT CMS3_k127_7078558_5 1237149.C900_05228 5.761e-95 320.0 COG1196@1|root,COG1196@2|Bacteria,4NHAC@976|Bacteroidetes,47MGD@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - ko:K09892 - - - - ko00000,ko03036 - - - - CMS3_k127_7078558_12 1254432.SCE1572_15390 1.232e-13 73.0 COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria,2YVNH@29|Myxococcales 28221|Deltaproteobacteria K Collagen triple helix repeat (20 copies) - - - - - - - - - - - - Collagen CMS3_k127_709313_5 1313421.JHBV01000138_gene1206 5.164e-23 109.0 COG5295@1|root,COG5295@2|Bacteria,4NF3S@976|Bacteroidetes,1ISQ8@117747|Sphingobacteriia 976|Bacteroidetes UW domain, Protein - - - - - - - - - - - - Collagen,Peptidase_S74 CMS3_k127_709313_6 1380600.AUYN01000003_gene17 3.464e-06 56.0 COG0860@1|root,COG1572@1|root,COG0860@2|Bacteria,COG1572@2|Bacteria,4NQCQ@976|Bacteroidetes,1IIJ2@117743|Flavobacteriia 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 CMS3_k127_709313_0 926549.KI421517_gene513 0.0 1521.0 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon CMS3_k127_709313_2 1237149.C900_03646 1.574e-53 190.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,47QDT@768503|Cytophagia 976|Bacteroidetes O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CMS3_k127_709313_4 1237149.C900_02903 6.237e-45 172.0 COG1434@1|root,COG1434@2|Bacteria,4NNUT@976|Bacteroidetes,47QTX@768503|Cytophagia 976|Bacteroidetes S DUF218 domain - - - - - - - - - - - - DUF218 CMS3_k127_709313_1 1124780.ANNU01000021_gene2964 9.787e-148 502.0 COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,47YDH@768503|Cytophagia 976|Bacteroidetes L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - Exonuc_V_gamma,PDDEXK_1 CMS3_k127_709313_3 1349822.NSB1T_05405 3.462e-45 183.0 COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,2FMHG@200643|Bacteroidia,22W5V@171551|Porphyromonadaceae 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily addA - - - - - - - - - - - Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C CMS3_k127_7093897_3 641524.ADICYQ_4891 1.318e-49 177.0 COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,47MV2@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_7093897_1 509635.N824_07225 9.985e-93 313.0 COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,1IPJU@117747|Sphingobacteriia 976|Bacteroidetes JM Nucleotidyl transferase - - - - - - - - - - - - NTP_transferase CMS3_k127_7093897_2 313606.M23134_02763 3.629e-57 211.0 COG2334@1|root,COG2334@2|Bacteria,4NH00@976|Bacteroidetes,47QCK@768503|Cytophagia 976|Bacteroidetes S Phosphotransferase enzyme family mdsC - - - - - - - - - - - APH CMS3_k127_7093897_0 313595.P700755_001843 6.475e-264 824.0 COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1HXAT@117743|Flavobacteriia,4C379@83612|Psychroflexus 976|Bacteroidetes S Bacterial protein of unknown function (DUF885) - - - - - - - - - - - - DUF885 CMS3_k127_7131441_7 706587.Desti_1480 2.128e-49 181.0 COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase bamR - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_7131441_0 1232410.KI421421_gene3436 1.198e-151 487.0 COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,42N5K@68525|delta/epsilon subdivisions,2WK1G@28221|Deltaproteobacteria,43TNB@69541|Desulfuromonadales 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase bamA GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 ko:K07539 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05593,R05594,R10696 RC01430,RC01431,RC03237 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_7131441_3 1232410.KI421412_gene166 1.32e-112 373.0 COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales 28221|Deltaproteobacteria C Alanine dehydrogenase/PNT, C-terminal domain bamQ - 1.1.1.368 ko:K07538 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05581 RC00850 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CMS3_k127_7131441_2 1121918.ARWE01000001_gene3599 1.111e-133 437.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WMIY@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Thiolase, C-terminal domain bktB - 2.3.1.16 ko:K07508 ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212 M00085,M00087 R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747 RC00004,RC00326,RC00405,RC01702 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N CMS3_k127_7131441_9 1121405.dsmv_2843 1.814e-38 164.0 COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria 28221|Deltaproteobacteria I TIGRFAM CoA-substrate-specific enzyme activase - - - - - - - - - - - - BcrAD_BadFG CMS3_k127_7131441_8 1121405.dsmv_2842 8.553e-44 181.0 COG1893@1|root,COG1893@2|Bacteria,1PHGH@1224|Proteobacteria,43A7I@68525|delta/epsilon subdivisions,2X25K@28221|Deltaproteobacteria,2MNME@213118|Desulfobacterales 28221|Deltaproteobacteria H Ketopantoate reductase PanE/ApbA C terminal - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C CMS3_k127_7131441_1 706587.Desti_1564 1.272e-146 474.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - - - - - - - - - - HGD-D CMS3_k127_7131441_6 406817.XNC1_2156 1.11e-74 273.0 COG1022@1|root,COG3321@1|root,COG1022@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,1SMTI@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q polyketide synthase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt CMS3_k127_7131441_5 258594.RPA0660 3.669e-81 278.0 COG1924@1|root,COG1924@2|Bacteria,1MY0N@1224|Proteobacteria,2U4V9@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Benzoyl-CoA reductase subunit - - 1.3.7.8 ko:K04115 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG CMS3_k127_7131441_4 1232410.KI421421_gene3272 3.69e-89 309.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2X5NK@28221|Deltaproteobacteria,43W2S@69541|Desulfuromonadales 28221|Deltaproteobacteria I BadF/BadG/BcrA/BcrD ATPase family - - - - - - - - - - - - BcrAD_BadFG CMS3_k127_7152869_2 1237149.C900_05006 5.487e-67 235.0 COG2318@1|root,COG2318@2|Bacteria,4NQ7Y@976|Bacteroidetes 976|Bacteroidetes S DinB family - - - - - - - - - - - - DinB CMS3_k127_7152869_3 1408433.JHXV01000001_gene978 1.862e-34 138.0 COG3637@1|root,COG3637@2|Bacteria,4NNFR@976|Bacteroidetes,1I1YP@117743|Flavobacteriia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - CMS3_k127_7152869_1 1380600.AUYN01000009_gene1876 5.795e-103 343.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1HYG0@117743|Flavobacteriia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - Cytochrom_NNT,FGE-sulfatase CMS3_k127_7152869_0 1121875.KB907547_gene3293 1.966e-186 592.0 COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,1HZF9@117743|Flavobacteriia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,TAT_signal CMS3_k127_7165535_2 1237149.C900_01969 1.075e-14 81.0 COG3291@1|root,COG3291@2|Bacteria,4NV3K@976|Bacteroidetes,47W7K@768503|Cytophagia 976|Bacteroidetes C Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_7165535_1 1349822.NSB1T_08355 6.71e-69 240.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,22WBV@171551|Porphyromonadaceae 976|Bacteroidetes K COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain rprY - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_7165535_0 313606.M23134_01093 8.355e-71 251.0 COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,47Y16@768503|Cytophagia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_7166967_0 1128912.GMES_0175 4.285e-154 497.0 COG1864@1|root,COG1864@2|Bacteria,1QSGF@1224|Proteobacteria,1S7ZV@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Endonuclease - - - ko:K01173 ko04210,map04210 - - - ko00000,ko00001,ko03029 - - - Endonuclease_NS,LTD,Trypsin_2 CMS3_k127_7166967_1 1454007.JAUG01000116_gene651 4.937e-23 113.0 COG2312@1|root,COG2312@2|Bacteria,4NW00@976|Bacteroidetes,1ITY5@117747|Sphingobacteriia 976|Bacteroidetes S Erythromycin esterase - - - ko:K06880 - - - - ko00000,ko01000,ko01504 - - - CarbopepD_reg_2,Erythro_esteras CMS3_k127_7166967_2 621372.ACIH01000033_gene575 1.087e-17 89.0 COG5528@1|root,COG5528@2|Bacteria,1VW9Q@1239|Firmicutes,4HWSC@91061|Bacilli,26YQB@186822|Paenibacillaceae 91061|Bacilli S Predicted integral membrane protein (DUF2269) - - - - - - - - - - - - DUF2269 CMS3_k127_720198_6 1237149.C900_05167 1.348e-35 137.0 COG5504@1|root,COG5504@2|Bacteria,4NFZP@976|Bacteroidetes,47N7G@768503|Cytophagia 976|Bacteroidetes O Gliding motility protein, GldB gldB - - - - - - - - - - - - CMS3_k127_720198_5 1237149.C900_01511 2.749e-73 261.0 COG0438@1|root,COG0438@2|Bacteria,4NI16@976|Bacteroidetes,47KFJ@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_720198_1 1237149.C900_01512 1.497e-102 336.0 COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,47JCH@768503|Cytophagia 976|Bacteroidetes L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD CMS3_k127_720198_2 1237149.C900_01514 3.797e-94 311.0 COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,47KW3@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_720198_0 1124780.ANNU01000006_gene2848 3.414e-119 394.0 COG3424@1|root,COG3424@2|Bacteria,4NDZU@976|Bacteroidetes,47JU1@768503|Cytophagia 976|Bacteroidetes Q PFAM chalcone and stilbene bcsA - - - - - - - - - - - Chal_sti_synt_C,Chal_sti_synt_N CMS3_k127_720198_3 153721.MYP_4431 1.214e-90 308.0 COG0382@1|root,COG0382@2|Bacteria,4NK26@976|Bacteroidetes,47N2W@768503|Cytophagia 976|Bacteroidetes H UbiA prenyltransferase family - - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA CMS3_k127_720198_7 102232.GLO73106DRAFT_00026910 4.286e-32 147.0 COG2931@1|root,COG3210@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,1GC1J@1117|Cyanobacteria 1117|Cyanobacteria QU Polymorphic membrane protein, Chlamydia - - - - - - - - - - - - Cadherin CMS3_k127_720198_4 686340.Metal_2132 1.446e-86 325.0 COG2373@1|root,COG3209@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,1QV7E@1224|Proteobacteria,1T3HZ@1236|Gammaproteobacteria 1236|Gammaproteobacteria M TIGRFAM Outer membrane protein - - - - - - - - - - - - - CMS3_k127_7218742_0 1237149.C900_01647 0.0 1638.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,47NAM@768503|Cytophagia 976|Bacteroidetes F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 CMS3_k127_7218742_13 1237149.C900_01639 1.02e-70 244.0 COG1309@1|root,COG1309@2|Bacteria,4NQ99@976|Bacteroidetes,47QGN@768503|Cytophagia 976|Bacteroidetes K PFAM Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CMS3_k127_7218742_6 1237149.C900_01638 6.008e-121 402.0 COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,47KE9@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_7218742_11 1279009.ADICEAN_02065 1.925e-94 322.0 COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47MFI@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 CMS3_k127_7218742_1 643867.Ftrac_0544 0.0 1472.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47ME1@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS3_k127_7218742_5 1237149.C900_01635 2.005e-158 509.0 COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07098 - - - - ko00000 - - - Metallophos CMS3_k127_7218742_14 1279009.ADICEAN_00639 9.01e-47 181.0 COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,4NN9A@976|Bacteroidetes,47QQI@768503|Cytophagia 976|Bacteroidetes T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 CMS3_k127_7218742_10 1237149.C900_01630 2.58e-100 353.0 COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,47KA3@768503|Cytophagia 976|Bacteroidetes L Helix-hairpin-helix motif - - - - - - - - - - - - HHH_3 CMS3_k127_7218742_18 1237149.C900_01629 4.904e-28 123.0 COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,47Q92@768503|Cytophagia 976|Bacteroidetes L photosystem II stabilization - - - - - - - - - - - - - CMS3_k127_7218742_8 1237149.C900_01626 1.225e-112 374.0 COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,47KQC@768503|Cytophagia 976|Bacteroidetes M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - - - - - - - - - - LGT CMS3_k127_7218742_3 153721.MYP_3805 1.88e-208 665.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,4NHXQ@976|Bacteroidetes,47JFU@768503|Cytophagia 976|Bacteroidetes H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase CMS3_k127_7218742_12 1237149.C900_01621 6.87e-79 270.0 COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,47K17@768503|Cytophagia 976|Bacteroidetes J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm CMS3_k127_7218742_2 1237149.C900_01620 3.555e-220 687.0 COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,47MQI@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_7218742_16 1237149.C900_01619 2.123e-39 147.0 COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,47R56@768503|Cytophagia 976|Bacteroidetes IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_7218742_19 269798.CHU_1399 2.281e-24 108.0 2DNED@1|root,32UIS@2|Bacteria,4NUJS@976|Bacteroidetes,47RRD@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7218742_4 1237149.C900_01617 8.374e-193 612.0 COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,47JS3@768503|Cytophagia 976|Bacteroidetes G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C CMS3_k127_7218742_7 1237149.C900_01616 1.365e-116 392.0 COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,47M54@768503|Cytophagia 976|Bacteroidetes K Fibronectin-binding protein A N-terminus (FbpA) - - - - - - - - - - - - DUF814,FbpA CMS3_k127_7218742_9 1120968.AUBX01000013_gene3470 2.802e-107 353.0 COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,47JF0@768503|Cytophagia 976|Bacteroidetes S of the beta-lactamase superfamily I phnP - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 CMS3_k127_7218742_17 1121904.ARBP01000002_gene7032 2.856e-32 127.0 2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,47RX3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7218742_15 1124780.ANNU01000045_gene2318 4.659e-40 152.0 COG0784@1|root,COG0784@2|Bacteria,4NQW4@976|Bacteroidetes,47Q9X@768503|Cytophagia 976|Bacteroidetes T PFAM response regulator receiver - - - - - - - - - - - - Response_reg CMS3_k127_7291643_1 1237149.C900_02460 2.149e-76 261.0 COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes,47KKW@768503|Cytophagia 976|Bacteroidetes S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport CMS3_k127_7291643_0 1305737.JAFX01000001_gene700 1.001e-169 539.0 COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,47KXT@768503|Cytophagia 976|Bacteroidetes J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C CMS3_k127_7291643_2 1237149.C900_02464 2.314e-67 238.0 28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,47MAE@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF5103) - - - - - - - - - - - - DUF5103 CMS3_k127_7300586_2 1237149.C900_03404 2.445e-69 246.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2 CMS3_k127_7300586_1 1124780.ANNU01000089_gene313 1.995e-228 720.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47KUQ@768503|Cytophagia 976|Bacteroidetes E PFAM Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS3_k127_7300586_0 1239962.C943_01988 3.568e-287 901.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,47JEZ@768503|Cytophagia 976|Bacteroidetes EU Peptidase S9, prolyl oligopeptidase active site domain protein - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 CMS3_k127_7300586_4 1237149.C900_05112 2.704e-34 134.0 COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia 976|Bacteroidetes S PFAM Membrane protein of yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 CMS3_k127_7300586_5 398720.MED217_06517 8.291e-15 83.0 COG3595@1|root,COG3595@2|Bacteria,4NIA2@976|Bacteroidetes,1I0CY@117743|Flavobacteriia,2XJ61@283735|Leeuwenhoekiella 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_7300586_3 1237149.C900_04853 1.239e-64 224.0 COG2316@1|root,COG2316@2|Bacteria,4NU4P@976|Bacteroidetes 976|Bacteroidetes S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD CMS3_k127_7332238_6 1237149.C900_05256 3.416e-49 184.0 COG1131@1|root,COG1131@2|Bacteria,4NHPD@976|Bacteroidetes,47KQD@768503|Cytophagia 976|Bacteroidetes V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran,TerB CMS3_k127_7332238_4 1279009.ADICEAN_01203 2.399e-60 217.0 COG1434@1|root,COG1434@2|Bacteria,4NNYV@976|Bacteroidetes,47PRX@768503|Cytophagia 976|Bacteroidetes S PFAM DUF218 domain - - - - - - - - - - - - DUF218 CMS3_k127_7332238_1 1237149.C900_05254 0.0 1015.0 COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia 976|Bacteroidetes Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7332238_2 1237149.C900_05253 6.229e-105 345.0 COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia 976|Bacteroidetes Q ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_7332238_3 1237149.C900_05252 2.234e-80 273.0 COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 CMS3_k127_7332238_0 1237149.C900_03907 0.0 1082.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_7332238_9 867900.Celly_3070 1.547e-07 53.0 COG3738@1|root,COG3738@2|Bacteria,4NM46@976|Bacteroidetes,1I1JU@117743|Flavobacteriia,1FA28@104264|Cellulophaga 976|Bacteroidetes S protein conserved in bacteria - - - ko:K09974 - - - - ko00000 - - - DUF1287 CMS3_k127_7332238_7 634956.Geoth_3670 4.954e-29 117.0 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,1WGSP@129337|Geobacillus 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 CMS3_k127_7332238_5 313595.P700755_003963 1.968e-51 189.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_7332238_8 1121904.ARBP01000009_gene4214 2.129e-09 64.0 2DMX7@1|root,32U79@2|Bacteria,4NUE1@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7336188_4 313606.M23134_03334 2.058e-37 164.0 COG1520@1|root,COG3209@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - SBBP CMS3_k127_7336188_2 1121904.ARBP01000001_gene5565 2.942e-55 222.0 COG2706@1|root,COG3468@1|root,COG4733@1|root,COG5184@1|root,COG2706@2|Bacteria,COG3468@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria 2|Bacteria DZ guanyl-nucleotide exchange factor activity Dcc - - ko:K03117,ko:K12684,ko:K19231,ko:K20276 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02044 1.B.12,1.B.12.4,2.A.64 - - CHU_C,Cu_amine_oxidN1,Lactonase,TIG,fn3 CMS3_k127_7336188_1 643867.Ftrac_1104 2.858e-92 316.0 COG4249@1|root,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes,47UFX@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 CMS3_k127_7336188_0 1121904.ARBP01000002_gene7106 3.289e-106 361.0 COG4870@1|root,COG4870@2|Bacteria,4NGK1@976|Bacteroidetes,47MRK@768503|Cytophagia 976|Bacteroidetes O Papain family cysteine protease - - - - - - - - - - - - DUF4384,Peptidase_C1 CMS3_k127_7336188_5 1237149.C900_00534 3.941e-33 132.0 COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,47R7P@768503|Cytophagia 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrom_C,Cytochrome_CBB3 CMS3_k127_7336188_3 1121930.AQXG01000010_gene3116 7.862e-50 179.0 COG0599@1|root,COG0599@2|Bacteria,4NNPC@976|Bacteroidetes,1ITG4@117747|Sphingobacteriia 976|Bacteroidetes S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD CMS3_k127_7377567_3 504472.Slin_4617 1.005e-43 166.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47U5S@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7377567_0 1237149.C900_03021 1.445e-181 581.0 COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes 976|Bacteroidetes C Fe-S oxidoreductase - - - - - - - - - - - - B12-binding,Radical_SAM CMS3_k127_7377567_2 714943.Mucpa_3263 2.564e-58 213.0 COG0500@1|root,COG2226@2|Bacteria,4NICK@976|Bacteroidetes,1ITVA@117747|Sphingobacteriia 976|Bacteroidetes Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_25 CMS3_k127_7377567_1 102125.Xen7305DRAFT_00014090 1.135e-62 229.0 COG1216@1|root,COG1216@2|Bacteria,1GPV3@1117|Cyanobacteria,3VMF1@52604|Pleurocapsales 1117|Cyanobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_7377567_4 1444711.CCJF01000004_gene2156 9.979e-15 83.0 COG2820@1|root,COG2820@2|Bacteria 2|Bacteria F uridine phosphorylase activity - - 2.4.2.3 ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01876,R02484,R08229 RC00063 ko00000,ko00001,ko01000 - - - PNP_UDP_1 CMS3_k127_7377567_5 118161.KB235922_gene3807 7.044e-08 56.0 COG0457@1|root,COG0457@2|Bacteria,1GQEX@1117|Cyanobacteria 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_7388173_5 1237149.C900_04749 1.643e-16 81.0 COG1663@1|root,COG1663@2|Bacteria,4NE2I@976|Bacteroidetes,47M44@768503|Cytophagia 976|Bacteroidetes M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK CMS3_k127_7388173_0 1121904.ARBP01000009_gene4217 1.272e-138 450.0 COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes,47JGH@768503|Cytophagia 976|Bacteroidetes S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO - - - - - - - - - - - NIF3 CMS3_k127_7388173_1 1048983.EL17_02595 3.864e-92 309.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,47JBK@768503|Cytophagia 976|Bacteroidetes S Zn-ribbon protein, possibly nucleic acid-binding - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 CMS3_k127_7388173_3 313606.M23134_04482 3.405e-68 237.0 COG0406@1|root,COG0406@2|Bacteria,4NFX5@976|Bacteroidetes,47JSV@768503|Cytophagia 976|Bacteroidetes G phosphoglycerate mutase family gpm - - - - - - - - - - - His_Phos_1 CMS3_k127_7388173_4 1237149.C900_04754 9.398e-50 181.0 COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,47QEZ@768503|Cytophagia 976|Bacteroidetes Q PFAM thioesterase superfamily ydiI - 3.1.2.28 ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07262 RC00004,RC00174 ko00000,ko00001,ko00002,ko01000 - - - 4HBT,Hydrolase_3 CMS3_k127_7388173_2 1237149.C900_04755 3.927e-69 245.0 COG1169@1|root,COG1169@2|Bacteria,4NF6U@976|Bacteroidetes,47K5Z@768503|Cytophagia 976|Bacteroidetes HQ PFAM chorismate binding enzyme entC - 5.4.4.2 ko:K02361,ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind CMS3_k127_7579003_7 1237149.C900_04382 4.73e-25 105.0 COG1983@1|root,COG1983@2|Bacteria,4NUNU@976|Bacteroidetes,47RWN@768503|Cytophagia 976|Bacteroidetes KT PFAM PspC domain - - - - - - - - - - - - PspC CMS3_k127_7579003_3 929562.Emtol_2961 4.531e-112 370.0 COG1216@1|root,COG1216@2|Bacteria,4NFP0@976|Bacteroidetes,47K2G@768503|Cytophagia 976|Bacteroidetes S PFAM Glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 CMS3_k127_7579003_6 1237149.C900_04380 1.306e-42 158.0 COG0718@1|root,COG0718@2|Bacteria,4NQ37@976|Bacteroidetes,47R3V@768503|Cytophagia 976|Bacteroidetes S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd CMS3_k127_7579003_4 1237149.C900_04378 1.939e-106 368.0 COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C CMS3_k127_7579003_1 1237149.C900_04377 3.538e-207 655.0 COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,47MP5@768503|Cytophagia 976|Bacteroidetes E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic CMS3_k127_7579003_2 1239962.C943_03810 4.205e-162 522.0 COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,47KPD@768503|Cytophagia 976|Bacteroidetes J tRNA synthetase class II core domain (G, H, P, S and T) hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His CMS3_k127_7579003_5 760192.Halhy_0106 1.037e-62 219.0 COG0622@1|root,COG0622@2|Bacteria,4NM4G@976|Bacteroidetes,1IRXF@117747|Sphingobacteriia 976|Bacteroidetes S Phosphoesterase - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 CMS3_k127_7579003_0 313606.M23134_00615 1.982e-216 695.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_7599885_2 313606.M23134_00725 9.535e-93 314.0 COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia 976|Bacteroidetes S Predicted periplasmic lipoprotein (DUF2279) - - - - - - - - - - - - DUF2279 CMS3_k127_7599885_0 1237149.C900_04102 0.0 1227.0 COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47KQP@768503|Cytophagia 976|Bacteroidetes S PFAM Family of - - - - - - - - - - - - TamB CMS3_k127_7599885_1 1120966.AUBU01000002_gene2088 3.925e-141 461.0 COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,47JX0@768503|Cytophagia 976|Bacteroidetes O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CMS3_k127_7599885_3 1237149.C900_04100 8.84e-43 160.0 COG5496@1|root,COG5496@2|Bacteria,4P643@976|Bacteroidetes,47VXQ@768503|Cytophagia 976|Bacteroidetes S Thioesterase - - - - - - - - - - - - - CMS3_k127_7599885_4 926556.Echvi_2086 2.588e-40 152.0 COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,47QSI@768503|Cytophagia 976|Bacteroidetes O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB CMS3_k127_7602185_0 1218108.KB908291_gene762 1.819e-60 216.0 COG2378@1|root,COG2378@2|Bacteria,4NHIC@976|Bacteroidetes,1HZ87@117743|Flavobacteriia 976|Bacteroidetes K DNA-binding protein - - - - - - - - - - - - HTH_11,WYL CMS3_k127_7602185_1 518766.Rmar_2053 9.803e-19 101.0 COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NWCQ@976|Bacteroidetes 976|Bacteroidetes S Metallo-peptidase family M12 - - - - - - - - - - - - Reprolysin_3,Reprolysin_5 CMS3_k127_7607625_0 1237149.C900_00909 3.659e-101 351.0 COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,47KV2@768503|Cytophagia 976|Bacteroidetes M Lamin Tail Domain - - - - - - - - - - - - Big_5,CHU_C,LTD CMS3_k127_7607625_1 880071.Fleli_3983 2.152e-88 295.0 COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,47JMK@768503|Cytophagia 976|Bacteroidetes E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CMS3_k127_7612305_5 700598.Niako_6250 1.635e-30 123.0 COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,1ITI3@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 CMS3_k127_7612305_4 468059.AUHA01000003_gene2010 7.811e-56 203.0 COG0500@1|root,COG2226@2|Bacteria,4PM1K@976|Bacteroidetes,1IRV8@117747|Sphingobacteriia 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_23,Methyltransf_25,Methyltransf_31 CMS3_k127_7612305_6 269798.CHU_3634 9.585e-16 85.0 2E7GE@1|root,331Z7@2|Bacteria,4NWN3@976|Bacteroidetes,47RY7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7612305_0 1124780.ANNU01000019_gene1730 2.945e-321 990.0 COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,47K4P@768503|Cytophagia 976|Bacteroidetes M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C CMS3_k127_7612305_2 643867.Ftrac_2876 1.231e-110 364.0 COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,47K0S@768503|Cytophagia 976|Bacteroidetes F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C CMS3_k127_7612305_3 762903.Pedsa_1063 1.74e-83 282.0 COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1IQ8P@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM CMS3_k127_7612305_1 1237149.C900_04960 9.222e-219 696.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,47MTM@768503|Cytophagia 976|Bacteroidetes MU Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40,TPR_16,TPR_2,TPR_8 CMS3_k127_7757_31 471854.Dfer_2523 7.44e-17 85.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47JTW@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_7757_27 1211815.CBYP010000003_gene1000 2.714e-35 144.0 COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4ET1N@85013|Frankiales 201174|Actinobacteria GM NAD(P)H-binding - - - - - - - - - - - - Epimerase,NAD_binding_10,RmlD_sub_bind CMS3_k127_7757_23 1137281.D778_00942 8.923e-69 237.0 2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1I25Z@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7757_0 1237149.C900_00735 0.0 1497.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12 CMS3_k127_7757_1 1120966.AUBU01000002_gene2339 0.0 1054.0 COG2185@1|root,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,47JW5@768503|Cytophagia 976|Bacteroidetes I Methylmalonyl-CoA mutase mutB - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase CMS3_k127_7757_29 1237149.C900_00733 1.008e-31 138.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,47JP5@768503|Cytophagia 976|Bacteroidetes I Methylmalonyl-CoA mutase N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase CMS3_k127_7757_4 1237149.C900_00732 7.946e-234 731.0 COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,47KR6@768503|Cytophagia 976|Bacteroidetes L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N CMS3_k127_7757_10 1237149.C900_01113 5.802e-153 497.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity degQ - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 CMS3_k127_7757_20 1313421.JHBV01000022_gene4689 2.771e-88 302.0 COG3055@1|root,COG3055@2|Bacteria,4NWEV@976|Bacteroidetes,1IXYN@117747|Sphingobacteriia 976|Bacteroidetes S Kelch motif - - - - - - - - - - - - Kelch_1,Kelch_6 CMS3_k127_7757_18 1237149.C900_05312 8.125e-95 317.0 COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia 976|Bacteroidetes P PFAM Integral membrane protein TerC - - - - - - - - - - - - TerC CMS3_k127_7757_11 1237149.C900_04887 1.452e-149 478.0 COG0142@1|root,COG0142@2|Bacteria,4NET2@976|Bacteroidetes,47KFN@768503|Cytophagia 976|Bacteroidetes H Belongs to the FPP GGPP synthase family ispB - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt CMS3_k127_7757_22 1124780.ANNU01000024_gene3115 3.379e-70 239.0 COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,47Q53@768503|Cytophagia 976|Bacteroidetes K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ CMS3_k127_7757_16 1185876.BN8_05410 3.921e-108 358.0 COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,47JJ6@768503|Cytophagia 976|Bacteroidetes J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 CMS3_k127_7757_28 1237149.C900_02237 1.255e-33 132.0 2ADW0@1|root,313N0@2|Bacteria,4NSUW@976|Bacteroidetes,47R7E@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7757_2 1237149.C900_02236 6.396e-290 904.0 COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,47K6U@768503|Cytophagia 976|Bacteroidetes M Cell division protein FtsI penicillin-binding protein 2 ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PASTA,PBP_dimer,Transpeptidase CMS3_k127_7757_5 1237149.C900_02235 4.056e-206 651.0 COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,47JT3@768503|Cytophagia 976|Bacteroidetes M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS3_k127_7757_6 1237149.C900_02234 2.416e-202 635.0 COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,47KEP@768503|Cytophagia 976|Bacteroidetes M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 CMS3_k127_7757_12 1185876.BN8_05349 9.506e-146 474.0 COG0771@1|root,COG0771@2|Bacteria,4NEFF@976|Bacteroidetes,47KTX@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M CMS3_k127_7757_8 643867.Ftrac_3292 1.32e-180 571.0 COG0772@1|root,COG0772@2|Bacteria,4NFIM@976|Bacteroidetes,47K3R@768503|Cytophagia 976|Bacteroidetes D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE CMS3_k127_7757_13 1237149.C900_02231 1.934e-127 418.0 COG0707@1|root,COG0707@2|Bacteria,4NE6D@976|Bacteroidetes,47JXF@768503|Cytophagia 976|Bacteroidetes M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 CMS3_k127_7757_9 1237149.C900_02230 2.288e-167 539.0 COG0773@1|root,COG0773@2|Bacteria,4NE1V@976|Bacteroidetes,47KY0@768503|Cytophagia 976|Bacteroidetes M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS3_k127_7757_24 1237149.C900_02229 2.358e-67 237.0 COG1589@1|root,COG1589@2|Bacteria,4NGPN@976|Bacteroidetes,47PU4@768503|Cytophagia 976|Bacteroidetes M Cell division protein ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ CMS3_k127_7757_3 1237149.C900_02228 2.161e-245 761.0 COG0849@1|root,COG0849@2|Bacteria,4NE0V@976|Bacteroidetes,47K6I@768503|Cytophagia 976|Bacteroidetes D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA CMS3_k127_7757_7 1237149.C900_02227 2.213e-186 599.0 COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,47MUN@768503|Cytophagia 976|Bacteroidetes D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin CMS3_k127_7757_30 1392498.JQLH01000001_gene14 8.979e-29 121.0 COG4886@1|root,COG4886@2|Bacteria 2|Bacteria S regulation of response to stimulus - - - - - - - - - - - - - CMS3_k127_7757_17 1120965.AUBV01000003_gene466 2.518e-101 336.0 COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,47JII@768503|Cytophagia 976|Bacteroidetes F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 CMS3_k127_7757_25 1168034.FH5T_13080 2.376e-59 217.0 2C23X@1|root,31B63@2|Bacteria,4NS2W@976|Bacteroidetes,2FT67@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7757_26 443144.GM21_2023 1.1e-35 146.0 COG0671@1|root,COG0671@2|Bacteria,1RIRR@1224|Proteobacteria,42X79@68525|delta/epsilon subdivisions,2WSVG@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM phosphoesterase, PA-phosphatase related - - - - - - - - - - - - PAP2 CMS3_k127_7757_19 1237149.C900_04886 2.604e-90 302.0 COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,47NUJ@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS3_k127_7757_15 1237149.C900_04877 8.526e-112 368.0 COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47KF6@768503|Cytophagia 976|Bacteroidetes V TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA gldA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_7757_21 471854.Dfer_4470 1.55e-75 260.0 COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,47KPQ@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated ABC transporter permease protein GldF gldF - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 CMS3_k127_7757_14 1124780.ANNU01000024_gene3135 7.209e-116 386.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia 976|Bacteroidetes N ABC transporter substrate-binding component GldG gldG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux CMS3_k127_869665_0 1250005.PHEL85_3151 6.799e-211 664.0 COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,1HZ0C@117743|Flavobacteriia,3VX83@52959|Polaribacter 976|Bacteroidetes S Carbohydrate esterase, sialic acid-specific acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA CMS3_k127_869665_2 760192.Halhy_3399 2.971e-45 175.0 COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,1J078@117747|Sphingobacteriia 976|Bacteroidetes S KR domain - - - ko:K07124 - - - - ko00000 - - - adh_short CMS3_k127_869665_3 1392489.JPOL01000003_gene167 8.633e-24 101.0 COG1278@1|root,COG1278@2|Bacteria,4NURE@976|Bacteroidetes,1I50Z@117743|Flavobacteriia,2XKC5@283735|Leeuwenhoekiella 976|Bacteroidetes K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CMS3_k127_869665_1 1313301.AUGC01000006_gene86 6.442e-84 283.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS3_k127_943976_2 1121904.ARBP01000005_gene4643 1.615e-22 98.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_943976_1 1124780.ANNU01000035_gene277 2.628e-123 398.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,47MF7@768503|Cytophagia 976|Bacteroidetes IQ TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_943976_0 1124780.ANNU01000035_gene276 2.356e-243 757.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,47JS2@768503|Cytophagia 976|Bacteroidetes C dihydrolipoamide dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim CMS3_k127_952865_19 643867.Ftrac_1115 1.675e-47 185.0 2FI0F@1|root,3433Q@2|Bacteria,4P46Y@976|Bacteroidetes,47VJN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_952865_8 1237149.C900_05604 1.773e-141 463.0 COG0845@1|root,COG0845@2|Bacteria,4NGSC@976|Bacteroidetes,47TMZ@768503|Cytophagia 976|Bacteroidetes M HlyD membrane-fusion protein of T1SS - - - - - - - - - - - - HlyD,HlyD_3,HlyD_D23 CMS3_k127_952865_5 1048983.EL17_06275 1.023e-191 607.0 COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,47JWH@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_952865_6 643867.Ftrac_3119 2.471e-180 576.0 COG1538@1|root,COG1538@2|Bacteria,4NGXM@976|Bacteroidetes,47KVY@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_952865_3 926549.KI421517_gene1476 1.601e-195 618.0 COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,47KAQ@768503|Cytophagia 976|Bacteroidetes F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,ASL_C,Lyase_1 CMS3_k127_952865_7 1237149.C900_05610 4.954e-148 476.0 COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,47KY6@768503|Cytophagia 976|Bacteroidetes C PFAM 2Fe-2S iron-sulfur cluster binding domain dmpP - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 CMS3_k127_952865_0 1237149.C900_05611 5.191e-265 827.0 COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia 976|Bacteroidetes E PFAM peptidase M3A and M3B thimet oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N CMS3_k127_952865_14 984262.SGRA_3856 1.251e-63 224.0 COG1225@1|root,COG1225@2|Bacteria,4NGWI@976|Bacteroidetes,1IS6D@117747|Sphingobacteriia 976|Bacteroidetes O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA CMS3_k127_952865_18 269798.CHU_2272 2.17e-51 190.0 29R44@1|root,30C5C@2|Bacteria,4NN15@976|Bacteroidetes,47PN2@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_952865_1 1237149.C900_05621 2.662e-254 794.0 COG2759@1|root,COG2759@2|Bacteria,4NG3E@976|Bacteroidetes,47T90@768503|Cytophagia 976|Bacteroidetes F Formate--tetrahydrofolate ligase fhs GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS CMS3_k127_952865_11 1227739.Hsw_4062 1.668e-95 320.0 COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia 976|Bacteroidetes C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ CMS3_k127_952865_9 1237149.C900_04831 5.561e-140 453.0 COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,47NVE@768503|Cytophagia 976|Bacteroidetes I Fatty acid desaturase alkB - 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase CMS3_k127_952865_21 1124780.ANNU01000021_gene3021 1.422e-23 108.0 2EKQA@1|root,33EE3@2|Bacteria,4NYQM@976|Bacteroidetes,47T4Z@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_952865_13 1237149.C900_04824 1.773e-74 252.0 COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes 976|Bacteroidetes L Phenylacetate-CoA oxygenase paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P CMS3_k127_952865_10 1237149.C900_04823 4.323e-105 348.0 COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,47VWV@768503|Cytophagia 976|Bacteroidetes S Phenylacetic acid catabolic protein paaC - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC CMS3_k127_952865_16 643867.Ftrac_0269 1.621e-58 209.0 COG3460@1|root,COG3460@2|Bacteria 2|Bacteria Q phenylacetate catabolic process paaB - - ko:K02610 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - PaaB CMS3_k127_952865_4 1237149.C900_04821 5.626e-195 610.0 COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,47TVD@768503|Cytophagia 976|Bacteroidetes S Phenylacetic acid catabolic protein paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC CMS3_k127_952865_17 643867.Ftrac_0272 4.924e-57 204.0 COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,47XSQ@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_4,TetR_C_5,TetR_N CMS3_k127_952865_24 1189612.A33Q_1960 0.0005507 48.0 2F4IN@1|root,33X8B@2|Bacteria,4P3SW@976|Bacteroidetes,47UZN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_952865_12 1124780.ANNU01000021_gene3007 2.229e-79 278.0 COG0086@1|root,COG0086@2|Bacteria,4NG2I@976|Bacteroidetes,47Y4X@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_952865_15 1237149.C900_00381 8.156e-62 219.0 COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,47PTY@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_952865_2 1237149.C900_05629 8.885e-213 684.0 COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,47M43@768503|Cytophagia 976|Bacteroidetes KT PFAM PspC domain - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - DUF2807,PspC CMS3_k127_952865_20 1237149.C900_05630 1.028e-39 148.0 COG1695@1|root,COG1695@2|Bacteria,4NSI4@976|Bacteroidetes,47Q8F@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR CMS3_k127_962831_3 926549.KI421517_gene786 8.085e-111 369.0 COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,47JB9@768503|Cytophagia 976|Bacteroidetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH CMS3_k127_962831_4 1279009.ADICEAN_03725 1.594e-61 217.0 COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,47R0S@768503|Cytophagia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_962831_1 1237149.C900_03428 2.699e-198 627.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47NKU@768503|Cytophagia 976|Bacteroidetes T Sigma-54 interaction domain - - - - - - - - - - - - Response_reg,Sigma54_activat CMS3_k127_962831_2 1237149.C900_03429 2.358e-189 610.0 COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,47Y2W@768503|Cytophagia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Hpt,Reg_prop,Response_reg CMS3_k127_962831_0 1237149.C900_03432 8.674e-230 759.0 COG3291@1|root,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia 976|Bacteroidetes Q cell adhesion involved in biofilm formation - - - - - - - - - - - - Big_5,PKD CMS3_k127_962831_6 1341181.FLJC2902T_19520 2.105e-34 154.0 COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,2NS7P@237|Flavobacterium 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - Big_2,CHU_C,HYR,SprB,fn3 CMS3_k127_966472_14 1120951.AUBG01000011_gene2328 1.212e-43 166.0 2C3PP@1|root,2Z954@2|Bacteria,4NIZX@976|Bacteroidetes,1I116@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_966472_7 42345.XP_008798855.1 2.595e-113 372.0 COG0115@1|root,KOG0975@2759|Eukaryota,37P5K@33090|Viridiplantae,3G79E@35493|Streptophyta,3KUE5@4447|Liliopsida 35493|Streptophyta E Amino-transferase class IV - - - - - - - - - - - - Aminotran_4,Methyltransf_16 CMS3_k127_966472_11 643867.Ftrac_2433 1.922e-85 289.0 COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,47PAU@768503|Cytophagia 976|Bacteroidetes P Inositol monophosphatase family cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P CMS3_k127_966472_12 643867.Ftrac_2434 7.78e-77 261.0 COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,47NAS@768503|Cytophagia 976|Bacteroidetes P Catalyzes the synthesis of activated sulfate cysC GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase CMS3_k127_966472_4 1237149.C900_03116 6.38e-149 475.0 COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,47JCC@768503|Cytophagia 976|Bacteroidetes EH TIGRFAM sulfate adenylyltransferase, small subunit cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct CMS3_k127_966472_1 1237149.C900_03118 2.363e-224 701.0 COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia 976|Bacteroidetes P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily - - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - GTP_EFTU CMS3_k127_966472_3 866536.Belba_0746 1.647e-154 494.0 COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,47JM1@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d CMS3_k127_966472_9 643867.Ftrac_2391 2.466e-101 337.0 COG1250@1|root,COG1250@2|Bacteria,4NF2W@976|Bacteroidetes,47XHJ@768503|Cytophagia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain paaH - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N CMS3_k127_966472_2 1237149.C900_03122 3.054e-163 518.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KTK@768503|Cytophagia 976|Bacteroidetes S PFAM ATPase associated with various cellular activities moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 CMS3_k127_966472_5 1237149.C900_03123 6.275e-147 477.0 COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,47JPW@768503|Cytophagia 976|Bacteroidetes O peptidyl-prolyl isomerase surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N_3 CMS3_k127_966472_10 1237149.C900_03124 2.704e-96 323.0 COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,47NE3@768503|Cytophagia 976|Bacteroidetes O Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - - - - - - - - - - Rotamase_2 CMS3_k127_966472_6 1237149.C900_03125 2.066e-119 407.0 COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia 976|Bacteroidetes O peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 CMS3_k127_966472_13 1237149.C900_03126 1.283e-47 174.0 COG2172@1|root,COG2172@2|Bacteria,4NV3J@976|Bacteroidetes,47RU2@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 CMS3_k127_966472_15 269798.CHU_0194 2.36e-35 138.0 COG1366@1|root,COG1366@2|Bacteria,4NT5G@976|Bacteroidetes,47RJ2@768503|Cytophagia 976|Bacteroidetes T STAS domain - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS CMS3_k127_966472_0 1237149.C900_03128 2.032e-243 769.0 COG2208@1|root,COG2208@2|Bacteria,4NJMJ@976|Bacteroidetes,47JNJ@768503|Cytophagia 976|Bacteroidetes KT PFAM Stage II sporulation protein E (SpoIIE) - - - - - - - - - - - - GAF_2,SpoIIE CMS3_k127_966472_8 1237149.C900_03138 7.25e-105 342.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,47KQV@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH CMS3_k127_971204_1 388413.ALPR1_13974 2.107e-84 301.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_971204_2 388413.ALPR1_13979 8.204e-17 83.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QZJ@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_971204_0 1121904.ARBP01000005_gene4643 2.658e-185 610.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_976347_3 388413.ALPR1_02505 1.579e-175 554.0 COG3507@1|root,COG3507@2|Bacteria,4NEIZ@976|Bacteroidetes,47KME@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolases family 43 - - - - - - - - - - - - Glyco_hydro_43 CMS3_k127_976347_12 1250232.JQNJ01000001_gene1074 4.392e-53 191.0 COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1I22W@117743|Flavobacteriia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - YCII CMS3_k127_976347_7 985255.APHJ01000025_gene1007 1.245e-126 416.0 COG0668@1|root,COG0668@2|Bacteria,4NJ1Q@976|Bacteroidetes,1HZHG@117743|Flavobacteriia 976|Bacteroidetes M Conserved TM helix - - - - - - - - - - - - TM_helix CMS3_k127_976347_18 509190.Cseg_3557 3.912e-11 70.0 COG0454@1|root,COG0456@2|Bacteria,1RB0Q@1224|Proteobacteria,2U6TH@28211|Alphaproteobacteria 28211|Alphaproteobacteria K -acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 CMS3_k127_976347_16 278957.ABEA03000108_gene1266 2.645e-19 97.0 COG0500@1|root,COG0500@2|Bacteria,46V7N@74201|Verrucomicrobia,3K8BC@414999|Opitutae 414999|Opitutae Q methyltransferase - - - - - - - - - - - - Methyltransf_25 CMS3_k127_976347_17 1137281.D778_00476 2.473e-11 69.0 2E0EQ@1|root,32W15@2|Bacteria,4NTKT@976|Bacteroidetes,1I3XF@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_976347_19 313590.MED134_07389 0.0003881 44.0 COG1361@1|root,COG4254@1|root,COG5184@1|root,COG1361@2|Bacteria,COG4254@2|Bacteria,COG5184@2|Bacteria,4NMB8@976|Bacteroidetes,1IJKA@117743|Flavobacteriia,37FU7@326319|Dokdonia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - Big_3_3,CHU_C,Calx-beta,DUF11,HYR,SdrD_B CMS3_k127_976347_9 926562.Oweho_0882 5.97e-97 327.0 COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia,2PAMQ@246874|Cryomorphaceae 976|Bacteroidetes IQ Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2,ketoacyl-synt CMS3_k127_976347_6 269798.CHU_0384 2.785e-140 456.0 COG0304@1|root,COG0304@2|Bacteria,4NKN3@976|Bacteroidetes,47UCF@768503|Cytophagia 976|Bacteroidetes IQ Beta-ketoacyl synthase, C-terminal domain - - - - - - - - - - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_976347_14 269798.CHU_0385 1.434e-35 139.0 COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,47S6H@768503|Cytophagia 976|Bacteroidetes IQ Phosphopantetheine attachment site - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_976347_5 714943.Mucpa_6797 1.722e-143 466.0 COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1ISKA@117747|Sphingobacteriia 976|Bacteroidetes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS3_k127_976347_10 714943.Mucpa_6796 2.908e-94 314.0 COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1IRV1@117747|Sphingobacteriia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_976347_4 714943.Mucpa_6795 1.377e-164 523.0 COG4990@1|root,COG4990@2|Bacteria,4NFZX@976|Bacteroidetes,1IPPX@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4872) - - - - - - - - - - - - BtrH_N,DUF4872 CMS3_k127_976347_13 269798.CHU_0389 5.228e-50 182.0 2CE7N@1|root,30Q80@2|Bacteria,4NNKP@976|Bacteroidetes,47RMH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_976347_2 269798.CHU_0390 3.995e-178 564.0 COG0332@1|root,COG0332@2|Bacteria,4NE5Q@976|Bacteroidetes,47KWN@768503|Cytophagia 976|Bacteroidetes I PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III darB - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III_C,Thiolase_N,ketoacyl-synt CMS3_k127_976347_8 269798.CHU_0391 1.814e-109 361.0 COG0716@1|root,COG0716@2|Bacteria,4NHTB@976|Bacteroidetes,47PXR@768503|Cytophagia 976|Bacteroidetes C Dialkylrecorsinol condensing enzyme DarA darA - - - - - - - - - - - - CMS3_k127_976347_15 269798.CHU_0392 5.104e-24 108.0 2C56J@1|root,32YW7@2|Bacteria,4NUU4@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_976347_11 1237149.C900_05616 1.925e-57 206.0 COG2353@1|root,COG2353@2|Bacteria,4NPGK@976|Bacteroidetes 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_976347_1 760192.Halhy_3998 5.98e-303 938.0 COG0405@1|root,COG0405@2|Bacteria,4NG3X@976|Bacteroidetes,1IPXR@117747|Sphingobacteriia 976|Bacteroidetes E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS3_k127_976347_0 1484460.JSWG01000006_gene3008 0.0 1401.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia 976|Bacteroidetes G BNR Asp-box repeat - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_995289_3 313603.FB2170_15638 6.797e-71 246.0 arCOG02770@1|root,33PR0@2|Bacteria,4P237@976|Bacteroidetes,1I7R8@117743|Flavobacteriia 976|Bacteroidetes S CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_995289_1 1267211.KI669560_gene1467 3.185e-166 531.0 COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase M61 - - - - - - - - - - - - PDZ_2,Peptidase_M61 CMS3_k127_995289_5 1267211.KI669560_gene1467 6.461e-16 83.0 COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase M61 - - - - - - - - - - - - PDZ_2,Peptidase_M61 CMS3_k127_995289_7 570268.ANBB01000050_gene4011 2.681e-11 75.0 COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4EHUW@85012|Streptosporangiales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,CBM_2,Peptidase_S9 CMS3_k127_995289_6 313606.M23134_05365 8.6e-15 86.0 COG3227@1|root,COG3291@1|root,COG3975@1|root,COG4733@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG3975@2|Bacteria,COG4733@2|Bacteria,4PKQC@976|Bacteroidetes,47SGA@768503|Cytophagia 976|Bacteroidetes E Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - PKD,Peptidase_M9,Peptidase_M9_N CMS3_k127_995289_4 1185876.BN8_02041 1.727e-47 175.0 2E69N@1|root,330XJ@2|Bacteria,4NYHG@976|Bacteroidetes,47X3N@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_995289_2 1105031.HMPREF1141_2139 3.924e-83 280.0 28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,24BKB@186801|Clostridia,36DST@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function (DUF4256) - - - - - - - - - - - - DUF4256 CMS3_k127_995289_0 1121912.AUHD01000005_gene1847 2.759e-208 659.0 COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1HWMZ@117743|Flavobacteriia 976|Bacteroidetes V beta-lactamase - - - - - - - - - - - - Beta-lactamase,Beta-lactamase2,DUF3471 ## 3241 queries scanned ## Total time (seconds): 119.92306113243103 ## Rate: 27.03 q/s