## Sun Nov 10 17:18:09 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS3_bin.54.fa -m mmseqs --itype genome -o CMS3_bin.54 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS3_bin.54 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS3_k127_1006772_0	98439.AJLL01000010_gene1388	5.5e-211	664.0	COG1770@1|root,COG1770@2|Bacteria,1G1RH@1117|Cyanobacteria,1JHGU@1189|Stigonemataceae	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_1006772_1	338966.Ppro_0044	2.337e-126	414.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS3_k127_1016296_0	1242864.D187_005418	5.871e-182	576.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria	1224|Proteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
CMS3_k127_1016296_1	331869.BAL199_12636	2.534e-140	455.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS3_k127_1031925_1	1123278.KB893427_gene1235	1.307e-46	181.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1031925_0	234267.Acid_3219	4.901e-50	203.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1031925_3	675814.VIC_002896	3.792e-17	87.0	2ATAH@1|root,31ITJ@2|Bacteria,1RIQF@1224|Proteobacteria,1SBJ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1031925_2	1120963.KB894497_gene2189	2.694e-29	128.0	COG2913@1|root,COG2913@2|Bacteria,1N2JT@1224|Proteobacteria,1S9TE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1032809_1	1297569.MESS2_760019	1.783e-54	196.0	COG0190@1|root,COG0190@2|Bacteria,1N8AY@1224|Proteobacteria,2TUBX@28211|Alphaproteobacteria,43HXE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS3_k127_1032809_2	243231.GSU0233	5.081e-37	149.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43TU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
CMS3_k127_1032809_3	247490.KSU1_B0184	4.819e-25	111.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS3_k127_1032809_4	1123023.JIAI01000001_gene6458	3.075e-23	111.0	COG0500@1|root,COG2226@2|Bacteria,2HENF@201174|Actinobacteria,4DYP7@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_1032809_0	1267533.KB906736_gene1246	4.12e-86	290.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_1034425_0	314230.DSM3645_23181	2.041e-193	615.0	COG0516@1|root,COG0516@2|Bacteria,2IX43@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS3_k127_1034425_2	204669.Acid345_2712	3.556e-130	444.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
CMS3_k127_1034425_5	1123242.JH636434_gene4430	1.715e-39	162.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2IYFX@203682|Planctomycetes	203682|Planctomycetes	KTU	Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,Response_reg
CMS3_k127_1034425_4	296587.XP_002507190.1	2.613e-43	170.0	COG0800@1|root,2QVAJ@2759|Eukaryota,37RSU@33090|Viridiplantae	33090|Viridiplantae	G	khg kdpg	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase,RraA-like
CMS3_k127_1034425_8	1229485.AMYV01000128_gene1417	1.442e-06	59.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1J4GB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	degQ	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0031224,GO:0031226,GO:0031233,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051603,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	1.3.1.74,3.4.21.107	ko:K04771,ko:K04772,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
CMS3_k127_1034425_9	1382306.JNIM01000001_gene2816	4.21e-05	55.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_1034425_3	562970.Btus_0884	1.153e-117	389.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,278S1@186823|Alicyclobacillaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_1034425_1	521674.Plim_4103	8.702e-176	563.0	COG0677@1|root,COG0677@2|Bacteria,2IXVX@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_1034425_6	448385.sce9324	4.01e-39	153.0	COG0746@1|root,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2X9X1@28221|Deltaproteobacteria,2YW7C@29|Myxococcales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_1034425_7	1423321.AS29_05475	4.238e-07	58.0	2DY61@1|root,348B1@2|Bacteria,1VZWP@1239|Firmicutes,4HYNS@91061|Bacilli,1ZHBE@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1051886_2	1201290.M902_0296	3.45e-12	75.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,42VAD@68525|delta/epsilon subdivisions,2WRMT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
CMS3_k127_1051886_3	575540.Isop_1923	2.162e-09	70.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1640
CMS3_k127_1051886_0	1120985.AUMI01000001_gene2075	8.157e-86	307.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4H2CM@909932|Negativicutes	909932|Negativicutes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
CMS3_k127_1051886_1	756272.Plabr_0628	1.036e-83	291.0	COG0568@1|root,COG0568@2|Bacteria,2IXI3@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_1053896_8	1236541.BALL01000003_gene555	1.601e-19	91.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,2Q8UB@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM Helix-turn-helix, type 11 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24
CMS3_k127_1053896_7	388399.SSE37_07298	3.844e-30	123.0	COG0346@1|root,COG0346@2|Bacteria,1N0XB@1224|Proteobacteria,2UD3M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
CMS3_k127_1053896_4	575540.Isop_1807	5.602e-72	254.0	COG0047@1|root,COG0047@2|Bacteria,2IYT2@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CMS3_k127_1053896_0	886293.Sinac_5423	9.359e-261	835.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
CMS3_k127_1053896_3	330214.NIDE0322	3.348e-91	318.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CMS3_k127_1053896_1	234267.Acid_5819	3.871e-165	537.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_1053896_2	234267.Acid_5820	1.437e-93	328.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_1053896_5	1123278.KB893427_gene1235	2.986e-44	183.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1053896_6	498848.TaqDRAFT_5452	2.625e-35	140.0	COG4373@1|root,COG4373@2|Bacteria,1WMCU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
CMS3_k127_1068048_0	234267.Acid_4278	3.985e-46	189.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
CMS3_k127_1072318_23	50452.A0A087GTW8	4.345e-05	54.0	2CUIV@1|root,2S4E5@2759|Eukaryota,37UIM@33090|Viridiplantae,3GIX7@35493|Streptophyta	35493|Streptophyta	S	Microsomal glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	MAPEG
CMS3_k127_1072318_2	224325.AF_1664	7.936e-209	679.0	COG0209@1|root,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,245VM@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
CMS3_k127_1072318_19	237368.SCABRO_01699	1.055e-23	105.0	COG0228@1|root,COG0228@2|Bacteria,2J0X7@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS3_k127_1072318_7	717605.Theco_2126	7.953e-83	280.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26RCU@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS3_k127_1072318_15	237368.SCABRO_01701	1.23e-33	135.0	COG0335@1|root,COG0335@2|Bacteria,2IZVX@203682|Planctomycetes	203682|Planctomycetes	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS3_k127_1072318_21	886293.Sinac_3316	9.817e-20	96.0	COG0792@1|root,COG0792@2|Bacteria,2J0GX@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS3_k127_1072318_10	391625.PPSIR1_02161	4.335e-56	206.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2YUWH@29|Myxococcales	28221|Deltaproteobacteria	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS3_k127_1072318_14	313628.LNTAR_20283	1.396e-34	138.0	2A42S@1|root,30SMP@2|Bacteria	2|Bacteria	S	Nickel-containing superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
CMS3_k127_1072318_9	1142394.PSMK_27020	5.937e-59	218.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,Peptidase_M42
CMS3_k127_1072318_16	290397.Adeh_3086	8.818e-32	129.0	2EE9W@1|root,3384B@2|Bacteria,1NCE1@1224|Proteobacteria,42VUH@68525|delta/epsilon subdivisions,2WSA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
CMS3_k127_1072318_5	404589.Anae109_3086	5.183e-99	330.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
CMS3_k127_1072318_3	404589.Anae109_3085	5.39e-135	442.0	COG5557@1|root,COG5557@2|Bacteria,1R7R0@1224|Proteobacteria,42P0Z@68525|delta/epsilon subdivisions,2X7KR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
CMS3_k127_1072318_4	204669.Acid345_2712	5.243e-103	364.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
CMS3_k127_1072318_6	1379698.RBG1_1C00001G0780	4.591e-83	290.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
CMS3_k127_1072318_20	1232410.KI421425_gene1570	8.26e-22	102.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
CMS3_k127_1072318_12	1379698.RBG1_1C00001G0779	1.073e-54	214.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
CMS3_k127_1072318_18	323848.Nmul_A2660	1.197e-28	124.0	COG0737@1|root,COG0737@2|Bacteria,1RFNB@1224|Proteobacteria,2VR8M@28216|Betaproteobacteria,372HK@32003|Nitrosomonadales	28216|Betaproteobacteria	C	to Cytochrome c-554 precursor (C554) (Hydroxylamine oxidoreductase-linked cytochrome) pir A59036 cytochrome c554, tetraheme, precursor - Nitrosomonas europaea	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_1072318_8	247490.KSU1_D0789	1.941e-75	271.0	COG0771@1|root,COG0771@2|Bacteria,2IX53@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_1072318_11	416348.Hlac_2824	5.808e-56	227.0	COG3291@1|root,arCOG02508@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
CMS3_k127_1072318_1	314230.DSM3645_16765	2.184e-228	758.0	COG0653@1|root,COG0653@2|Bacteria,2IXIT@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_1072318_0	344747.PM8797T_17864	0.0	1342.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2IXN2@203682|Planctomycetes	203682|Planctomycetes	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS3_k127_1072318_13	1449126.JQKL01000026_gene2438	6.645e-47	186.0	2DB6N@1|root,2Z7HZ@2|Bacteria,1V3A4@1239|Firmicutes,25DUU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4392)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4392
CMS3_k127_1072318_17	1209989.TepiRe1_1239	9.852e-29	131.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_1072792_0	861299.J421_1115	5.084e-80	278.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1072792_1	661478.OP10G_0834	9.719e-23	100.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_1082873_8	595460.RRSWK_06019	1.152e-53	201.0	COG1519@1|root,COG1519@2|Bacteria,2IYCJ@203682|Planctomycetes	203682|Planctomycetes	M	transferase	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
CMS3_k127_1082873_4	269799.Gmet_3033	4.386e-107	372.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,43SVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS3_k127_1082873_0	1379698.RBG1_1C00001G0777	0.0	1082.0	COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
CMS3_k127_1082873_5	1191523.MROS_1572	9.837e-96	325.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
CMS3_k127_1082873_2	1191523.MROS_1571	3.9e-133	436.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hybB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	iAPECO1_1312.APECO1_3427,iE2348C_1286.E2348C_3282,iECABU_c1320.ECABU_c34010,iECOK1_1307.ECOK1_3414,iECS88_1305.ECS88_3377,iUMN146_1321.UM146_01380,iUTI89_1310.UTI89_C3417	NrfD
CMS3_k127_1082873_6	1379698.RBG1_1C00001G0775	5.37e-85	296.0	COG0484@1|root,COG0484@2|Bacteria,2NQUM@2323|unclassified Bacteria	2|Bacteria	O	Class III cytochrome C family	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
CMS3_k127_1082873_1	1379698.RBG1_1C00001G0776	1.535e-215	697.0	COG2864@1|root,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
CMS3_k127_1082873_9	398511.BpOF4_21299	7.447e-17	89.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,1ZFIZ@1386|Bacillus	91061|Bacilli	L	Staphylococcal nuclease homologues	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS3_k127_1082873_3	886293.Sinac_5942	1.628e-129	426.0	COG0527@1|root,COG0527@2|Bacteria,2IY8N@203682|Planctomycetes	203682|Planctomycetes	E	aspartate kinase, monofunctional class	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS3_k127_1082873_7	211165.AJLN01000143_gene1402	1.041e-56	200.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria,1JKZJ@1189|Stigonemataceae	1117|Cyanobacteria	J	Endoribonuclease L-PSP	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
CMS3_k127_1091318_0	521674.Plim_0748	2.032e-74	256.0	COG0302@1|root,COG0302@2|Bacteria,2IYUA@203682|Planctomycetes	203682|Planctomycetes	H	PFAM GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS3_k127_1091318_3	8479.XP_005314644.1	2.101e-35	147.0	KOG3538@1|root,KOG4597@2759|Eukaryota,38EQB@33154|Opisthokonta,3BB8S@33208|Metazoa,3E52Q@33213|Bilateria,485NV@7711|Chordata,4994V@7742|Vertebrata,4CJ8V@8459|Testudines	33208|Metazoa	O	BPTI/Kunitz family of serine protease inhibitors.	mig-6	GO:0000003,GO:0000902,GO:0002119,GO:0002164,GO:0005575,GO:0005576,GO:0005604,GO:0007275,GO:0008150,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009987,GO:0016043,GO:0031012,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0044421,GO:0048598,GO:0048856,GO:0048869,GO:0062023,GO:0071840	-	-	-	-	-	-	-	-	-	-	ADAM_spacer1,Kunitz_BPTI,PLAC,TSP_1,WAP
CMS3_k127_1091318_5	318161.Sden_2836	9.071e-18	86.0	2E4BN@1|root,332AD@2|Bacteria,1N9VK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1091318_4	395961.Cyan7425_3875	7.686e-18	96.0	COG0500@1|root,COG2226@2|Bacteria,1GIXW@1117|Cyanobacteria,3KJAY@43988|Cyanothece	1117|Cyanobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_1091318_1	247490.KSU1_C0304	8.014e-52	201.0	COG1039@1|root,COG1039@2|Bacteria,2IZ83@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1091318_6	522772.Dacet_2858	2.623e-06	55.0	COG1366@1|root,COG1366@2|Bacteria,2GFWN@200930|Deferribacteres	200930|Deferribacteres	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS3_k127_1091318_2	926560.KE387023_gene1933	4.182e-39	162.0	COG5624@1|root,COG5624@2|Bacteria,1WJK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1105123_1	159450.NH14_20845	1.215e-14	76.0	28H7B@1|root,2Z7JJ@2|Bacteria,1MX57@1224|Proteobacteria,2W2KR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5
CMS3_k127_1105123_0	448385.sce4883	2.612e-144	463.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WUHZ@28221|Deltaproteobacteria,2YX7U@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_1107597_0	880073.Calab_3321	4.779e-263	822.0	COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
CMS3_k127_1107597_1	883080.HMPREF9697_02964	7.469e-11	64.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2TTGG@28211|Alphaproteobacteria,3JTB0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
CMS3_k127_1114908_1	236097.ADG881_3286	2.89e-65	229.0	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1XP8B@135619|Oceanospirillales	135619|Oceanospirillales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS3_k127_1114908_0	349521.HCH_02595	4.904e-75	260.0	COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,1S4BU@1236|Gammaproteobacteria,1XPIQ@135619|Oceanospirillales	135619|Oceanospirillales	S	COG3103 SH3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,SH3_3,SH3_4
CMS3_k127_1114908_2	1415754.JQMK01000002_gene3448	8.768e-29	118.0	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,46408@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_1122573_1	452637.Oter_4232	2.447e-27	117.0	2F7MR@1|root,34028@2|Bacteria,46VN7@74201|Verrucomicrobia,3K85B@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1122573_0	1142394.PSMK_20510	2.034e-50	190.0	COG0030@1|root,COG0030@2|Bacteria,2IYD7@203682|Planctomycetes	203682|Planctomycetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS3_k127_1122573_2	903818.KI912268_gene892	6.862e-16	79.0	COG1104@1|root,COG1104@2|Bacteria,3Y389@57723|Acidobacteria	2|Bacteria	E	PFAM aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_1126710_11	1089550.ATTH01000001_gene1477	1.081e-52	208.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_1126710_10	756272.Plabr_2354	8.056e-56	206.0	COG0611@1|root,COG0611@2|Bacteria,2IZG9@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_1126710_13	404380.Gbem_1263	3.53e-31	129.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria,43V70@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS3_k127_1126710_6	196164.23494244	1.211e-86	292.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,22K6P@1653|Corynebacteriaceae	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS3_k127_1126710_9	1121430.JMLG01000002_gene1035	5.657e-59	210.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS3_k127_1126710_8	237368.SCABRO_00189	1.228e-64	226.0	COG1945@1|root,COG1945@2|Bacteria,2IZIF@203682|Planctomycetes	203682|Planctomycetes	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	-	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
CMS3_k127_1126710_4	404589.Anae109_1276	3.323e-102	351.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,42QED@68525|delta/epsilon subdivisions,2WJWR@28221|Deltaproteobacteria,2Z18F@29|Myxococcales	28221|Deltaproteobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS3_k127_1126710_7	1379698.RBG1_1C00001G0708	2.916e-77	269.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_1126710_16	1313304.CALK_1267	7.825e-23	106.0	COG1406@1|root,COG1406@2|Bacteria	2|Bacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
CMS3_k127_1126710_14	521674.Plim_2874	4.415e-30	124.0	COG0745@1|root,COG0745@2|Bacteria,2J01B@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_1126710_15	1142394.PSMK_24200	1.411e-28	119.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_1126710_2	926569.ANT_16830	1.408e-127	423.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi	200795|Chloroflexi	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS3_k127_1126710_3	880073.Calab_0862	2.886e-103	349.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS3_k127_1126710_1	1121104.AQXH01000005_gene189	8.305e-169	548.0	COG0025@1|root,COG0025@2|Bacteria,4PKJ5@976|Bacteroidetes	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_1126710_12	1094980.Mpsy_1273	1.275e-35	151.0	COG3875@1|root,arCOG02046@2157|Archaea,2XVDD@28890|Euryarchaeota,2N9Q8@224756|Methanomicrobia	224756|Methanomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS3_k127_1126710_0	502025.Hoch_2090	3.944e-242	773.0	COG3488@1|root,COG3488@2|Bacteria,1MXUW@1224|Proteobacteria,42YAW@68525|delta/epsilon subdivisions,2WTPQ@28221|Deltaproteobacteria,2YU9D@29|Myxococcales	28221|Deltaproteobacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
CMS3_k127_1126710_5	266117.Rxyl_2107	4.246e-102	351.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS3_k127_113539_1	365046.Rta_32480	7.923e-13	84.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
CMS3_k127_113539_2	1410620.SHLA_17c000810	8.921e-09	71.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2V8W2@28211|Alphaproteobacteria,4BF2R@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS3_k127_113539_0	529818.AMSG_05318T0	2.956e-32	149.0	KOG3607@1|root,KOG3607@2759|Eukaryota	2759|Eukaryota	L	metalloendopeptidase activity	KMT2D	-	2.1.1.43,2.7.11.1	ko:K06261,ko:K08867,ko:K09187,ko:K14972,ko:K20371	ko00310,ko04512,ko04611,ko04640,ko04934,map00310,map04512,map04611,map04640,map04934	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko01001,ko01009,ko03000,ko03036,ko04090,ko04131	-	-	-	DC_STAMP,FYRC,FYRN,Laminin_G_3,PHD,Reprolysin_3,Reprolysin_4,SET,SH3_1,SH3_9,TSP_1,zf-HC5HC2H
CMS3_k127_1144426_12	1382359.JIAL01000001_gene557	1.237e-12	74.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria,2JJ61@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1144426_5	1353529.M899_0208	7.361e-85	320.0	COG2010@1|root,COG2010@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2MUN1@213481|Bdellovibrionales,2WPS4@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_1144426_4	886293.Sinac_1831	1.125e-116	387.0	COG1290@1|root,COG1290@2|Bacteria,2IYI0@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
CMS3_k127_1144426_3	530564.Psta_2936	2.907e-124	402.0	COG1290@1|root,COG1290@2|Bacteria,2IX3Q@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
CMS3_k127_1144426_8	886293.Sinac_1829	3.969e-42	168.0	COG0723@1|root,COG0723@2|Bacteria,2IZ3E@203682|Planctomycetes	203682|Planctomycetes	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS3_k127_1144426_13	862908.BMS_1857	2.895e-12	78.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CMS3_k127_1144426_9	344747.PM8797T_10589	6.635e-40	160.0	COG1597@1|root,COG1597@2|Bacteria,2IZX6@203682|Planctomycetes	203682|Planctomycetes	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_1144426_10	395961.Cyan7425_2513	1.048e-38	158.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria,3KHGC@43988|Cyanothece	1117|Cyanobacteria	S	PFAM Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
CMS3_k127_1144426_0	1142394.PSMK_11090	0.0	1225.0	COG0458@1|root,COG0458@2|Bacteria,2IXR6@203682|Planctomycetes	203682|Planctomycetes	F	Carbamoylphosphate synthase large subunit	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS3_k127_1144426_7	1163409.UUA_06858	1.321e-44	171.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,1XC9S@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS3_k127_1144426_11	886293.Sinac_1999	6.29e-32	130.0	COG5609@1|root,COG5609@2|Bacteria,2J0KX@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
CMS3_k127_1144426_6	886293.Sinac_1993	1.23e-48	177.0	COG5609@1|root,COG5609@2|Bacteria,2J0WE@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
CMS3_k127_1144426_1	278957.ABEA03000005_gene4430	2.702e-193	616.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_1144426_2	1047013.AQSP01000076_gene1470	1.872e-157	505.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_1165744_11	479434.Sthe_0808	3.003e-31	137.0	COG1807@1|root,COG1807@2|Bacteria,2GBE9@200795|Chloroflexi,27Z44@189775|Thermomicrobia	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1165744_12	596154.Alide2_2876	3.132e-28	126.0	COG2520@1|root,COG2520@2|Bacteria,1R01N@1224|Proteobacteria,2VYA0@28216|Betaproteobacteria,4AFUT@80864|Comamonadaceae	28216|Betaproteobacteria	D	TIGRFAM methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_1165744_10	1116369.KB890025_gene5109	6.166e-51	197.0	COG0438@1|root,COG0438@2|Bacteria,1R7HJ@1224|Proteobacteria,2U35C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS3_k127_1165744_9	756883.Halar_2989	6.58e-54	209.0	COG3119@1|root,arCOG02787@2157|Archaea	2157|Archaea	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1,3.1.6.6	ko:K01130,ko:K01133	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_1165744_14	471854.Dfer_0105	3.064e-06	59.0	COG2755@1|root,COG2755@2|Bacteria,4PAZ7@976|Bacteroidetes,47UVP@768503|Cytophagia	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1165744_4	290400.Jann_4252	4.233e-71	262.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1165744_5	1173026.Glo7428_2493	8.936e-69	246.0	COG1922@1|root,COG1922@2|Bacteria,1G2U3@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
CMS3_k127_1165744_1	1245469.S58_28630	9.018e-102	340.0	COG1215@1|root,COG1215@2|Bacteria,1R4ZM@1224|Proteobacteria,2U479@28211|Alphaproteobacteria,3K3R6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1165744_0	589865.DaAHT2_1748	1.256e-103	352.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,42M7Q@68525|delta/epsilon subdivisions,2WJ9Z@28221|Deltaproteobacteria,2MIK8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1165744_6	1116369.KB890025_gene5123	2.17e-63	231.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria	1224|Proteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_1165744_3	768671.ThimaDRAFT_3236	6.673e-74	263.0	COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,1RZH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1165744_8	768671.ThimaDRAFT_3246	1.245e-58	219.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,1RRUD@1236|Gammaproteobacteria,1WZ22@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS3_k127_1165744_7	41431.PCC8801_3878	4.352e-61	228.0	COG3307@1|root,COG3307@2|Bacteria,1G33N@1117|Cyanobacteria,3KGMG@43988|Cyanothece	1117|Cyanobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_1165744_13	478741.JAFS01000001_gene1111	9.227e-16	89.0	COG0392@1|root,COG0392@2|Bacteria,46YYT@74201|Verrucomicrobia,37GP8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_1165744_2	240016.ABIZ01000001_gene2310	4.004e-75	264.0	COG0367@1|root,COG0367@2|Bacteria,46UNK@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Asparagine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,GATase_7
CMS3_k127_117031_1	243231.GSU1703	1.241e-51	186.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,43TVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_117031_2	1499967.BAYZ01000124_gene2568	5.556e-47	177.0	COG3647@1|root,COG3647@2|Bacteria	2|Bacteria	S	Membrane	yjdF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
CMS3_k127_117031_5	1158609.I586_01991	2.883e-25	117.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,4AZEA@81852|Enterococcaceae	91061|Bacilli	O	Glycoprotease family	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_117031_0	1142394.PSMK_14290	1.14e-83	287.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_117031_3	1142394.PSMK_15440	8.671e-45	185.0	COG0706@1|root,COG0706@2|Bacteria,2IYA0@203682|Planctomycetes	203682|Planctomycetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,PDZ_2,YidC_periplas
CMS3_k127_117031_4	1499967.BAYZ01000170_gene5495	1.053e-36	147.0	COG5405@1|root,COG5405@2|Bacteria	2|Bacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	-	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS3_k127_1183194_2	742159.HMPREF0004_1004	0.0001128	54.0	COG0438@1|root,COG0438@2|Bacteria,1Q8II@1224|Proteobacteria,2WF59@28216|Betaproteobacteria,3T8NZ@506|Alcaligenaceae	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1183194_1	1144319.PMI16_01738	1.292e-91	316.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria,472K8@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_1183194_0	1382306.JNIM01000001_gene329	1.495e-169	541.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1192726_0	215803.DB30_2893	1.396e-138	448.0	COG0339@1|root,COG0339@2|Bacteria,1R4AJ@1224|Proteobacteria,43BI1@68525|delta/epsilon subdivisions,2WMHM@28221|Deltaproteobacteria,2YYTH@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	prlC1	-	3.4.24.15	ko:K01392	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
CMS3_k127_1192726_1	1499967.BAYZ01000073_gene2016	2.454e-59	212.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
CMS3_k127_1192726_2	1191523.MROS_1643	7.944e-10	60.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1217426_3	1142394.PSMK_18500	2.894e-56	209.0	COG1624@1|root,COG1624@2|Bacteria,2IZSP@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
CMS3_k127_1217426_1	886293.Sinac_2632	3.306e-152	502.0	COG0323@1|root,COG0323@2|Bacteria,2IXI2@203682|Planctomycetes	203682|Planctomycetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS3_k127_1217426_0	443143.GM18_0341	1.812e-279	877.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1217426_4	76114.ebA7211	4.443e-25	120.0	COG4932@1|root,COG4932@2|Bacteria,1PWBK@1224|Proteobacteria,2WBWH@28216|Betaproteobacteria,2KZ3K@206389|Rhodocyclales	206389|Rhodocyclales	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1217426_6	497965.Cyan7822_5103	1.329e-08	67.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
CMS3_k127_1217426_5	1205680.CAKO01000040_gene984	1.922e-13	82.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_1217426_2	1123508.JH636439_gene650	2.091e-56	202.0	COG0157@1|root,COG0157@2|Bacteria,2IYVV@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS3_k127_123131_4	330214.NIDE2245	4.263e-06	55.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_4,Fer4_5,Fer4_9
CMS3_k127_123131_1	756272.Plabr_1636	1.205e-141	470.0	COG4805@1|root,COG4805@2|Bacteria,2IY48@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS3_k127_123131_2	344747.PM8797T_11004	3.293e-86	299.0	COG0758@1|root,COG0758@2|Bacteria,2IX3D@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
CMS3_k127_123131_0	1121472.AQWN01000007_gene1136	1.29e-249	787.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia,260G2@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_123131_3	1207063.P24_14574	4.533e-24	108.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,2JQRA@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
CMS3_k127_1239871_1	1210884.HG799462_gene8511	3.424e-48	179.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_1239871_2	1125863.JAFN01000001_gene1546	3.386e-39	160.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1239871_0	1410624.JNKK01000001_gene722	8.134e-128	423.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,27K8I@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_1240884_1	1224136.AMFN01000003_gene3425	4.915e-38	159.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria	1224|Proteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_1240884_0	237368.SCABRO_02229	2.317e-73	262.0	COG0304@1|root,COG0304@2|Bacteria,2J1Z9@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_1240884_2	31870.EFQ31398	0.000488	48.0	COG1020@1|root,KOG1178@2759|Eukaryota,38HAR@33154|Opisthokonta,3NXWX@4751|Fungi,3RJB6@4890|Ascomycota,214V8@147550|Sordariomycetes,1EXYB@1028384|Glomerellales	4751|Fungi	Q	Condensation domain	-	GO:0000036,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006518,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0016053,GO:0016874,GO:0016879,GO:0019184,GO:0019290,GO:0019539,GO:0019725,GO:0019748,GO:0019752,GO:0030003,GO:0031168,GO:0031169,GO:0031667,GO:0031668,GO:0031669,GO:0032787,GO:0033554,GO:0034641,GO:0042592,GO:0042594,GO:0043043,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044550,GO:0044620,GO:0046394,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051188,GO:0051192,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0072330,GO:0098771,GO:0140104,GO:1901564,GO:1901566,GO:1901576,GO:1904091	-	ko:K22148	-	-	-	-	ko00000	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_1261346_8	13037.EHJ70238	1.6e-36	153.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,41W09@6656|Arthropoda,3SING@50557|Insecta,4429T@7088|Lepidoptera	33208|Metazoa	T	Thrombospondin C-terminal region	COMP	GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181	-	ko:K04659	ko04145,ko04151,ko04510,ko04512,ko05144,ko05165,map04145,map04151,map04510,map04512,map05144,map05165	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04147,ko04516	-	-	-	COMP,EGF,EGF_CA,TSP_3,TSP_C
CMS3_k127_1261346_3	1157490.EL26_13075	6.316e-95	314.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS3_k127_1261346_7	1142394.PSMK_03070	1.168e-50	188.0	COG0500@1|root,COG2226@2|Bacteria,2IYWE@203682|Planctomycetes	203682|Planctomycetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_1261346_6	1142394.PSMK_00140	1.57e-55	202.0	COG0163@1|root,COG0163@2|Bacteria,2IZBH@203682|Planctomycetes	203682|Planctomycetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CMS3_k127_1261346_5	886293.Sinac_1699	5.727e-71	252.0	COG0382@1|root,COG0382@2|Bacteria,2IX4Z@203682|Planctomycetes	203682|Planctomycetes	H	COG0382 4-hydroxybenzoate polyprenyltransferase and related	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_1261346_12	1449345.JHWC01000006_gene1034	2.88e-06	60.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2YMBU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
CMS3_k127_1261346_11	1124780.ANNU01000008_gene2741	5.305e-20	100.0	COG2017@1|root,COG2017@2|Bacteria,4NE32@976|Bacteroidetes,47P1W@768503|Cytophagia	976|Bacteroidetes	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1261346_9	756272.Plabr_1994	3.881e-34	147.0	COG0095@1|root,COG0095@2|Bacteria,2IZMX@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS3_k127_1261346_1	743719.PaelaDRAFT_2910	1.413e-175	564.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,26RUP@186822|Paenibacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
CMS3_k127_1261346_2	646529.Desaci_3733	4.18e-138	452.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
CMS3_k127_1261346_4	237368.SCABRO_00373	1.48e-92	315.0	COG3481@1|root,COG3481@2|Bacteria,2IX5B@203682|Planctomycetes	203682|Planctomycetes	S	Nucleic acid binding	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
CMS3_k127_1261346_0	266117.Rxyl_2540	8.575e-209	674.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_1261346_13	1464048.JNZS01000007_gene4555	2.907e-06	54.0	COG1366@1|root,COG1366@2|Bacteria,2IPRV@201174|Actinobacteria,4DE6R@85008|Micromonosporales	201174|Actinobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
CMS3_k127_1261346_10	7176.CPIJ016498-PA	2.864e-21	109.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,41W09@6656|Arthropoda,3SING@50557|Insecta,44Y9H@7147|Diptera	33208|Metazoa	O	Calcium ion binding. It is involved in the biological process described with cell adhesion	-	-	-	ko:K04659	ko04145,ko04151,ko04510,ko04512,ko05144,ko05165,map04145,map04151,map04510,map04512,map05144,map05165	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04147,ko04516	-	-	-	EGF_CA,TSP_3,TSP_C
CMS3_k127_1312859_1	880073.Calab_1549	7.56e-280	881.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS3_k127_1312859_2	1121904.ARBP01000016_gene5280	3.159e-167	532.0	COG0075@1|root,COG0075@2|Bacteria,4NH61@976|Bacteroidetes,47VRP@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily	phnW	-	2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830,ko:K03430	ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588,R04152	RC00006,RC00008,RC00018,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_1312859_0	575540.Isop_1100	0.0	1298.0	COG0841@1|root,COG0841@2|Bacteria,2J2CE@203682|Planctomycetes	203682|Planctomycetes	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_1312859_3	575540.Isop_1099	6.558e-93	319.0	COG0845@1|root,COG0845@2|Bacteria,2J330@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS3_k127_1312859_5	1259795.ARJK01000003_gene718	4.306e-19	91.0	COG0599@1|root,COG0599@2|Bacteria,1VFY0@1239|Firmicutes,25CIE@186801|Clostridia,42GT0@68295|Thermoanaerobacterales	186801|Clostridia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_1312859_4	589865.DaAHT2_2101	1.958e-33	131.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ybzH	-	-	-	-	-	-	-	-	-	-	-	DUF43,HTH_20,HTH_5
CMS3_k127_1312859_6	530564.Psta_3775	1.054e-07	54.0	COG1502@1|root,COG1502@2|Bacteria,2IY2H@203682|Planctomycetes	203682|Planctomycetes	I	Phospholipase_D-nuclease N-terminal	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS3_k127_1327482_11	713586.KB900536_gene1112	1.113e-13	78.0	COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria,1X10E@135613|Chromatiales	135613|Chromatiales	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS3_k127_1327482_12	1122225.AULQ01000001_gene1591	8.633e-10	68.0	COG4886@1|root,COG4886@2|Bacteria,4PM1T@976|Bacteroidetes,1HWWE@117743|Flavobacteriia	976|Bacteroidetes	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1327482_2	1123242.JH636435_gene2917	5.839e-94	332.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_1327482_5	497964.CfE428DRAFT_0921	1.016e-60	218.0	COG4112@1|root,COG4112@2|Bacteria,46V3C@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1327482_13	1121875.KB907553_gene31	9.837e-10	72.0	COG2885@1|root,COG3266@1|root,COG3291@1|root,COG2885@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia	976|Bacteroidetes	DZ	TIGRFAM Bacterial surface protein 26-residue repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,DUF285,TIG,TSP_3
CMS3_k127_1327482_6	1242864.D187_001047	1.783e-44	183.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
CMS3_k127_1327482_1	448385.sce3532	2.468e-141	462.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2YU80@29|Myxococcales	28221|Deltaproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS3_k127_1327482_7	240016.ABIZ01000001_gene5154	2.403e-39	166.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_1327482_8	861299.J421_1317	3.954e-24	118.0	COG0845@1|root,COG0845@2|Bacteria,1ZUCP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1327482_4	656024.FsymDg_4258	2.348e-78	268.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4EU28@85013|Frankiales	201174|Actinobacteria	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1327482_3	1167006.UWK_02172	5.45e-92	317.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42ZBZ@68525|delta/epsilon subdivisions,2X5D0@28221|Deltaproteobacteria,2MMNI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	MacB_PCD
CMS3_k127_1327482_10	1107311.Q767_06305	6.15e-18	87.0	2CENM@1|root,32S06@2|Bacteria,4NUGY@976|Bacteroidetes,1IIDA@117743|Flavobacteriia,2P0CQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1327482_9	314230.DSM3645_12996	1.419e-22	102.0	COG0640@1|root,COG0640@2|Bacteria,2J12M@203682|Planctomycetes	203682|Planctomycetes	K	transcriptional regulator, ArsR family protein	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS3_k127_1327482_0	1121918.ARWE01000001_gene2083	3.01e-160	516.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS3_k127_1348294_4	9818.XP_007942008.1	1.506e-43	173.0	COG0183@1|root,KOG1391@2759|Eukaryota,39QWG@33154|Opisthokonta,3BAQ0@33208|Metazoa,3CS5N@33213|Bilateria,481QU@7711|Chordata,491BS@7742|Vertebrata,3JCE3@40674|Mammalia,34V5P@311790|Afrotheria	33208|Metazoa	I	3-ketoacyl-CoA thiolase, mitochondrial	ACAA2	GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234	2.3.1.16,2.3.1.254	ko:K07508,ko:K17972	ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212	M00085,M00087	R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko03029	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1348294_2	880073.Calab_3204	5.711e-75	286.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_1348294_3	443144.GM21_2868	6.366e-64	229.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria,43T2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS3_k127_1348294_0	316067.Geob_0166	1.372e-137	449.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria,43UG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
CMS3_k127_1348294_1	1379698.RBG1_1C00001G0892	8.793e-137	443.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
CMS3_k127_1348294_5	909663.KI867150_gene859	7.274e-08	57.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria,2MREP@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_1358920_0	880073.Calab_3769	1.745e-97	325.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_1358920_1	234267.Acid_3938	6.794e-63	238.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_137935_0	1142394.PSMK_22770	5.471e-57	205.0	COG0029@1|root,COG0029@2|Bacteria,2IY30@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_137935_2	994573.T472_0213055	1.686e-09	68.0	COG0500@1|root,COG2226@2|Bacteria,1V6QV@1239|Firmicutes,24JPQ@186801|Clostridia,36IM9@31979|Clostridiaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS3_k127_137935_1	1131269.AQVV01000003_gene681	8.902e-32	131.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.13.12.21	ko:K15969	ko01057,ko01130,map01057,map01130	M00783	R06700	RC01658	ko00000,ko00001,ko00002,ko01000	-	-	-	ABM
CMS3_k127_1393591_0	595460.RRSWK_00671	7.124e-49	179.0	COG1244@1|root,COG1244@2|Bacteria,2IX1W@203682|Planctomycetes	203682|Planctomycetes	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_1393591_1	693661.Arcve_1723	9.29e-29	123.0	COG0546@1|root,arCOG02292@2157|Archaea,2XZX6@28890|Euryarchaeota,246FI@183980|Archaeoglobi	183980|Archaeoglobi	S	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS3_k127_1398416_1	521674.Plim_0648	4.718e-46	171.0	COG0036@1|root,COG0036@2|Bacteria,2IZKC@203682|Planctomycetes	203682|Planctomycetes	G	TIGRFAM Ribulose-phosphate 3-epimerase	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_1398416_2	638303.Thal_0879	6.272e-18	92.0	COG0406@1|root,COG0406@2|Bacteria,2G423@200783|Aquificae	200783|Aquificae	G	PFAM Phosphoglycerate mutase	pgmA	-	3.1.3.3	ko:K22305	ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130	-	R00582	RC00017	ko00000,ko00001,ko01000	-	-	-	His_Phos_1
CMS3_k127_1398416_0	1142394.PSMK_10710	1.406e-102	340.0	COG0777@1|root,COG0777@2|Bacteria,2IXWA@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_1398416_3	1122611.KB903940_gene1843	8.084e-07	59.0	COG2234@1|root,COG2234@2|Bacteria,2GIT0@201174|Actinobacteria,4EFVR@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase family M28	-	-	3.4.11.24	ko:K19702	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M28
CMS3_k127_1460938_1	1047013.AQSP01000134_gene1354	2.711e-157	498.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_1460938_7	1123242.JH636435_gene1674	7.061e-12	72.0	COG0582@1|root,COG0582@2|Bacteria,2IYXX@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS3_k127_1460938_0	1267533.KB906735_gene5020	6.059e-171	574.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_1460938_3	1123508.JH636453_gene5810	2.389e-46	177.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_1460938_8	1122609.AUGT01000005_gene1921	1.244e-09	72.0	COG2373@1|root,COG4412@1|root,COG5549@1|root,COG2373@2|Bacteria,COG4412@2|Bacteria,COG5549@2|Bacteria,2H2B4@201174|Actinobacteria,4DTD3@85009|Propionibacteriales	201174|Actinobacteria	O	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5
CMS3_k127_1460938_5	1123278.KB893427_gene1235	2.355e-20	104.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1460938_4	324602.Caur_0299	4.988e-29	134.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_1460938_6	1242864.D187_003608	5.863e-16	91.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
CMS3_k127_1460938_2	156889.Mmc1_2864	2.611e-119	392.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS3_k127_1468602_0	1519464.HY22_07105	1.984e-265	829.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_1468602_1	448385.sce3565	1.519e-75	272.0	COG2885@1|root,COG3391@1|root,COG5184@1|root,COG2885@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_1485317_0	527002.yaldo0001_40610	3.408e-19	91.0	2C95Z@1|root,3325I@2|Bacteria,1NNU6@1224|Proteobacteria,1SU1J@1236|Gammaproteobacteria,41HKK@629|Yersinia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1485317_3	1123487.KB892866_gene1758	7.506e-10	65.0	2EV02@1|root,33NF8@2|Bacteria,1NNVB@1224|Proteobacteria,2VY00@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Immunity protein 10	-	-	-	-	-	-	-	-	-	-	-	-	Imm10
CMS3_k127_1485317_4	315456.RF_0935	0.000255	47.0	2AHH5@1|root,317UK@2|Bacteria,1Q8QD@1224|Proteobacteria,2UXMQ@28211|Alphaproteobacteria,47GJV@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1485317_1	1454004.AW11_02813	2.805e-18	84.0	2DVMI@1|root,33WD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1486654_0	521674.Plim_3120	2.28e-159	513.0	COG0304@1|root,COG0304@2|Bacteria,2IX8X@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_1486654_3	1142394.PSMK_03130	1.408e-98	338.0	COG0304@1|root,COG0304@2|Bacteria,2IY1N@203682|Planctomycetes	203682|Planctomycetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_1486654_6	886293.Sinac_6211	2.525e-42	161.0	COG0764@1|root,COG0764@2|Bacteria,2IZWX@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS3_k127_1486654_7	314230.DSM3645_13430	1.265e-41	156.0	COG0236@1|root,COG0236@2|Bacteria,2J04I@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_1486654_8	886293.Sinac_6209	7.525e-39	152.0	COG0764@1|root,COG0764@2|Bacteria,2J09I@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS3_k127_1486654_2	880073.Calab_3585	9.089e-104	357.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
CMS3_k127_1486654_12	502025.Hoch_2677	3.312e-19	104.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_1486654_9	1192034.CAP_1358	6.4e-34	153.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
CMS3_k127_1486654_13	671143.DAMO_0230	1.588e-14	81.0	COG4083@1|root,COG4083@2|Bacteria	2|Bacteria	S	PFAM Transmembrane exosortase (Exosortase_EpsH)	groEL	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS3_k127_1486654_15	794903.OPIT5_01580	6.787e-06	57.0	28TF8@1|root,2ZFP9@2|Bacteria,46WSU@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1486654_4	1123242.JH636434_gene5235	3.585e-90	320.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_1486654_10	673862.BABL1_1066	1.496e-24	113.0	arCOG06621@1|root,33A1X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1486654_1	671143.DAMO_2498	7.577e-138	448.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_1486654_5	1254432.SCE1572_15940	1.423e-42	181.0	2DSXQ@1|root,33HVC@2|Bacteria,1N9KU@1224|Proteobacteria	1224|Proteobacteria	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1,Kazal_2
CMS3_k127_1486654_11	35128.Thaps23813	9.782e-22	113.0	29MB1@1|root,2RUKV@2759|Eukaryota,2XHB4@2836|Bacillariophyta	2836|Bacillariophyta	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1
CMS3_k127_1487651_0	575540.Isop_2783	1.038e-268	842.0	COG0556@1|root,COG0556@2|Bacteria,2IWS1@203682|Planctomycetes	203682|Planctomycetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS3_k127_149262_4	234267.Acid_5749	9.283e-96	323.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_149262_1	234267.Acid_3938	1.378e-170	570.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_149262_3	1121033.AUCF01000012_gene831	1.997e-125	413.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,2JQU5@204441|Rhodospirillales	204441|Rhodospirillales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS3_k127_149262_7	1168065.DOK_02166	3.106e-47	174.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria,1J6CI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MgtC family	mgtC	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_149262_10	1267533.KB906740_gene145	3.086e-10	67.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	MA20_44825	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS3_k127_149262_0	68170.KL590499_gene4927	3.801e-205	721.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4E8ZQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
CMS3_k127_149262_11	1158762.KB898065_gene1168	6.664e-05	48.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1X0JE@135613|Chromatiales	135613|Chromatiales	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
CMS3_k127_149262_6	102129.Lepto7375DRAFT_5814	6.788e-57	223.0	COG2755@1|root,COG2931@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,1G0DX@1117|Cyanobacteria,1H8AY@1150|Oscillatoriales	1117|Cyanobacteria	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF11,DUF4347,HemolysinCabind,Laminin_G_3,VCBS
CMS3_k127_149262_8	926560.KE387023_gene2369	7.411e-41	156.0	COG2050@1|root,COG2050@2|Bacteria,1WJVA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_149262_9	706587.Desti_2768	1.677e-12	79.0	COG0518@1|root,COG0518@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS3_k127_149262_2	234267.Acid_0873	9.362e-139	468.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_149262_5	1178825.ALIH01000015_gene1934	4.165e-67	237.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.14.10	ko:K01280	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8
CMS3_k127_1500644_4	575540.Isop_1367	1.376e-15	81.0	COG1191@1|root,COG1191@2|Bacteria,2IX9S@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_1500644_2	1120973.AQXL01000112_gene1102	2.471e-58	213.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,279KN@186823|Alicyclobacillaceae	91061|Bacilli	J	tRNA pseudouridine synthase	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS3_k127_1500644_0	521674.Plim_4161	6.046e-98	333.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1500644_1	1210884.HG799465_gene11632	1.678e-75	284.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1500644_3	595460.RRSWK_04987	2.256e-25	115.0	COG1595@1|root,COG1595@2|Bacteria,2IZ9U@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_1511590_2	1123276.KB893269_gene4794	2.751e-10	74.0	2D5HH@1|root,32TJ4@2|Bacteria,4PPRQ@976|Bacteroidetes,47YR4@768503|Cytophagia	976|Bacteroidetes	S	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CMS3_k127_1511590_1	335659.S23_23450	3.298e-12	80.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2U5ZN@28211|Alphaproteobacteria,3JY4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CMS3_k127_1511590_0	518766.Rmar_1280	1.38e-107	379.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,4NKF1@976|Bacteroidetes	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
CMS3_k127_1564999_0	1123508.JH636439_gene1480	1.585e-163	534.0	COG4581@1|root,COG4581@2|Bacteria,2IXFY@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS3_k127_1564999_1	1142394.PSMK_13460	4.842e-17	90.0	COG1716@1|root,COG1716@2|Bacteria,2J0SY@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS3_k127_1566367_1	1232437.KL661959_gene3108	1.949e-16	90.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria,2MPWS@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
CMS3_k127_1566367_0	946362.XP_004997743.1	1.118e-19	100.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_1566367_2	502025.Hoch_2677	1.416e-11	75.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_1567688_4	227086.JGI_V11_49680	5.17e-38	153.0	COG0402@1|root,KOG3968@2759|Eukaryota	2759|Eukaryota	F	imidazolonepropionase activity	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,M20_dimer,Peptidase_M20
CMS3_k127_1567688_1	1057002.KB905370_gene3364	5.517e-70	252.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,4BBQ5@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_1567688_5	886293.Sinac_3423	1.507e-20	106.0	2E9AB@1|root,333IA@2|Bacteria,2J0Z1@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1567688_3	530564.Psta_4608	6.16e-63	229.0	COG1100@1|root,COG1100@2|Bacteria,2IZ95@203682|Planctomycetes	203682|Planctomycetes	S	Small GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1567688_2	530564.Psta_4609	4.149e-69	253.0	COG1262@1|root,COG1262@2|Bacteria,2IZAZ@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
CMS3_k127_1567688_0	1227739.Hsw_0099	4.095e-87	295.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K00138,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_1567825_1	550540.Fbal_0857	1.207e-25	109.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_1567825_0	886293.Sinac_3192	1.542e-58	224.0	COG0501@1|root,COG0501@2|Bacteria,2J0VM@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
CMS3_k127_1567825_2	477974.Daud_1022	2.506e-20	98.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,2606K@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS3_k127_1577398_6	1192034.CAP_5682	2.29e-25	112.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,42SFZ@68525|delta/epsilon subdivisions,2WPY5@28221|Deltaproteobacteria,2Z0Z7@29|Myxococcales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_1577398_7	575540.Isop_1483	3.846e-20	96.0	COG3536@1|root,COG3536@2|Bacteria,2J0WS@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS3_k127_1577398_2	378806.STAUR_6221	2.01e-146	477.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YTZR@29|Myxococcales	28221|Deltaproteobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
CMS3_k127_1577398_3	886293.Sinac_4426	8.921e-109	361.0	COG0451@1|root,COG0451@2|Bacteria,2IZN3@203682|Planctomycetes	203682|Planctomycetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_1577398_9	797114.C475_18566	1.446e-09	70.0	arCOG07561@1|root,arCOG07561@2157|Archaea,2XV3J@28890|Euryarchaeota,23UWG@183963|Halobacteria	183963|Halobacteria	K	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1577398_10	1122622.ATWJ01000001_gene2442	5.913e-09	68.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634,ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	Cadherin,LolA,PPC
CMS3_k127_1577398_1	247490.KSU1_C0443	1.804e-154	509.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
CMS3_k127_1577398_0	1121930.AQXG01000003_gene2700	3.572e-160	520.0	COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,1IPJK@117747|Sphingobacteriia	976|Bacteroidetes	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_1577398_4	1047013.AQSP01000143_gene2008	5.505e-87	296.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
CMS3_k127_1577398_5	1142394.PSMK_p00540	1.032e-69	247.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS3_k127_1577398_8	1121428.DESHY_110458___1	4.994e-16	79.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,2614W@186807|Peptococcaceae	186801|Clostridia	J	class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_15989_1	1142394.PSMK_24450	1.411e-239	750.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS3_k127_15989_39	465515.Mlut_08300	0.0002561	51.0	COG0454@1|root,COG0456@2|Bacteria,2IR11@201174|Actinobacteria,1WA2E@1268|Micrococcaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_15989_0	1142394.PSMK_24440	0.0	1881.0	COG0086@1|root,COG2190@1|root,COG0086@2|Bacteria,COG2190@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS3_k127_15989_14	1142394.PSMK_26560	2.318e-54	193.0	COG0048@1|root,COG0048@2|Bacteria,2IZR1@203682|Planctomycetes	203682|Planctomycetes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS3_k127_15989_30	1394178.AWOO02000049_gene6165	7.054e-24	109.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4EIYG@85012|Streptosporangiales	201174|Actinobacteria	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
CMS3_k127_15989_12	756272.Plabr_4433	1.824e-57	203.0	COG0049@1|root,COG0049@2|Bacteria,2IZ7I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS3_k127_15989_2	1121448.DGI_2835	1.436e-221	706.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2M882@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_15989_20	1142394.PSMK_29190	1.518e-42	159.0	COG0051@1|root,COG0051@2|Bacteria,2IZQR@203682|Planctomycetes	203682|Planctomycetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS3_k127_15989_11	1142394.PSMK_29180	4.984e-60	214.0	COG0087@1|root,COG0087@2|Bacteria,2IY9T@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS3_k127_15989_21	1123242.JH636435_gene3131	6.595e-40	155.0	COG0088@1|root,COG0088@2|Bacteria,2IYU2@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS3_k127_15989_33	1123508.JH636455_gene15	1.022e-21	97.0	COG0089@1|root,COG0089@2|Bacteria,2J0VE@203682|Planctomycetes	203682|Planctomycetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS3_k127_15989_5	575540.Isop_2082	7.141e-110	362.0	COG0090@1|root,COG0090@2|Bacteria,2IXD9@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS3_k127_15989_24	314230.DSM3645_09382	4.319e-36	138.0	COG0185@1|root,COG0185@2|Bacteria,2J0BB@203682|Planctomycetes	203682|Planctomycetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS3_k127_15989_31	314230.DSM3645_09377	2.095e-23	104.0	COG0091@1|root,COG0091@2|Bacteria,2J023@203682|Planctomycetes	203682|Planctomycetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS3_k127_15989_7	1142394.PSMK_29120	5.082e-79	270.0	COG0092@1|root,COG0092@2|Bacteria,2IWWU@203682|Planctomycetes	203682|Planctomycetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS3_k127_15989_13	1123508.JH636455_gene20	3.554e-55	196.0	COG0197@1|root,COG0197@2|Bacteria,2IZPH@203682|Planctomycetes	203682|Planctomycetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS3_k127_15989_38	748224.HMPREF9436_00362	2.255e-08	59.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS3_k127_15989_35	1454202.PPBDW_80327___1	7.857e-20	92.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1XXXG@135623|Vibrionales	135623|Vibrionales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS3_k127_15989_22	1123242.JH636435_gene3122	3.983e-39	150.0	COG0093@1|root,COG0093@2|Bacteria,2IZMA@203682|Planctomycetes	203682|Planctomycetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS3_k127_15989_28	1210884.HG799465_gene12017	1.553e-25	109.0	COG0198@1|root,COG0198@2|Bacteria,2J0QM@203682|Planctomycetes	203682|Planctomycetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS3_k127_15989_10	266117.Rxyl_2143	3.6e-62	219.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CQ45@84995|Rubrobacteria	84995|Rubrobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS3_k127_15989_32	521674.Plim_0490	4.916e-22	96.0	COG0199@1|root,COG0199@2|Bacteria,2J0QE@203682|Planctomycetes	203682|Planctomycetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS3_k127_15989_19	875454.BAEW01000003_gene690	1.009e-42	163.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,22H9V@1570339|Peptoniphilaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS3_k127_15989_17	530564.Psta_2615	1.328e-47	177.0	COG0097@1|root,COG0097@2|Bacteria,2IZ8X@203682|Planctomycetes	203682|Planctomycetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS3_k127_15989_25	246194.CHY_2293	9.018e-36	140.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,42GIE@68295|Thermoanaerobacterales	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS3_k127_15989_16	314230.DSM3645_09312	4.391e-51	186.0	COG0098@1|root,COG0098@2|Bacteria,2IZ7J@203682|Planctomycetes	203682|Planctomycetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS3_k127_15989_23	273068.TTE2273	3.639e-37	144.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS3_k127_15989_3	1142394.PSMK_28990	1.575e-153	497.0	COG0201@1|root,COG0201@2|Bacteria,2IXN6@203682|Planctomycetes	203682|Planctomycetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS3_k127_15989_8	756272.Plabr_2076	8.619e-74	258.0	COG0024@1|root,COG0024@2|Bacteria,2IXPX@203682|Planctomycetes	203682|Planctomycetes	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS3_k127_15989_37	237368.SCABRO_03483	6.281e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,2J1IK@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS3_k127_15989_18	575540.Isop_2101	1.271e-45	168.0	COG0099@1|root,COG0099@2|Bacteria,2IZK8@203682|Planctomycetes	203682|Planctomycetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS3_k127_15989_15	1123242.JH636435_gene3112	2.642e-53	190.0	COG0100@1|root,COG0100@2|Bacteria,2IZCP@203682|Planctomycetes	203682|Planctomycetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS3_k127_15989_9	1304880.JAGB01000003_gene1185	1.586e-67	237.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS3_k127_15989_6	521674.Plim_0499	1.996e-105	355.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS3_k127_15989_29	391625.PPSIR1_23799	2.635e-24	111.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2Z32V@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS3_k127_15989_27	1322246.BN4_12170	3.657e-31	128.0	COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WQRN@28221|Deltaproteobacteria,2MBWX@213115|Desulfovibrionales	28221|Deltaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_15989_26	351160.RRC22	2.654e-35	154.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_15989_4	530564.Psta_4767	5.17e-125	411.0	COG0082@1|root,COG0082@2|Bacteria,2IY2Z@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS3_k127_15989_34	102129.Lepto7375DRAFT_5083	2.226e-21	110.0	COG3591@1|root,COG3591@2|Bacteria,1G8I7@1117|Cyanobacteria,1HDMZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin,Trypsin_2
CMS3_k127_15989_36	926550.CLDAP_30620	2.999e-14	87.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8,TIG
CMS3_k127_162979_6	247490.KSU1_B0240	4.862e-33	145.0	2CFWI@1|root,32S2N@2|Bacteria,2J08K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_162979_4	575540.Isop_2796	3.975e-55	204.0	COG0159@1|root,COG0159@2|Bacteria,2IWYG@203682|Planctomycetes	203682|Planctomycetes	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS3_k127_162979_3	247490.KSU1_B0645	1.781e-59	223.0	COG1207@1|root,COG1207@2|Bacteria,2IXBV@203682|Planctomycetes	203682|Planctomycetes	M	Sugar nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
CMS3_k127_162979_0	1219084.AP014508_gene1090	3e-135	445.0	COG0205@1|root,COG0205@2|Bacteria,2GC8H@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_162979_2	314278.NB231_16608	1.139e-89	310.0	COG0306@1|root,COG0306@2|Bacteria,1QCP3@1224|Proteobacteria,1S2WJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS3_k127_162979_5	251229.Chro_4749	2.634e-36	153.0	COG0793@1|root,COG0793@2|Bacteria,1G30Q@1117|Cyanobacteria,3VMBN@52604|Pleurocapsales	1117|Cyanobacteria	M	Tricorn protease C1 domain	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
CMS3_k127_162979_1	886293.Sinac_1564	2.87e-119	385.0	COG0568@1|root,COG0568@2|Bacteria,2IXI3@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_1644889_5	1128421.JAGA01000002_gene163	1.485e-115	383.0	COG1063@1|root,COG1063@2|Bacteria,2NPK3@2323|unclassified Bacteria	2|Bacteria	E	Zinc-binding dehydrogenase	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1644889_6	204669.Acid345_2793	1.187e-112	377.0	COG0436@1|root,COG0436@2|Bacteria,3Y2TF@57723|Acidobacteria,2JHQX@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Aminotransferase, class I	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_1644889_12	575540.Isop_0616	1.511e-36	151.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CMS3_k127_1644889_9	1303518.CCALI_02446	2.675e-53	195.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_1644889_8	1144275.COCOR_01998	3.648e-80	283.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS3_k127_1644889_10	568703.LGG_00321	5.991e-51	200.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC,NUDIX
CMS3_k127_1644889_11	1123242.JH636434_gene4606	1.783e-43	178.0	COG0727@1|root,COG0727@2|Bacteria,2IZGA@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
CMS3_k127_1644889_3	867903.ThesuDRAFT_01689	4.579e-125	414.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WCJS@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS3_k127_1644889_7	530564.Psta_3982	8.291e-83	283.0	COG1692@1|root,COG1692@2|Bacteria,2IXR1@203682|Planctomycetes	203682|Planctomycetes	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
CMS3_k127_1644889_0	886293.Sinac_2253	8.155e-161	522.0	COG1418@1|root,COG1418@2|Bacteria,2IX35@203682|Planctomycetes	203682|Planctomycetes	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS3_k127_1644889_4	517418.Ctha_0233	3.508e-117	408.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS3_k127_1644889_2	1142394.PSMK_07550	9.689e-158	512.0	COG2152@1|root,COG2152@2|Bacteria,2IYI2@203682|Planctomycetes	203682|Planctomycetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
CMS3_k127_1644889_1	909663.KI867150_gene2732	2.733e-160	510.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42QDF@68525|delta/epsilon subdivisions,2WMG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
CMS3_k127_1644889_15	1463825.JNXC01000005_gene2397	0.0007178	45.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria,4E2P0@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
CMS3_k127_1644889_14	1047013.AQSP01000144_gene872	0.0001711	53.0	COG1470@1|root,COG2755@1|root,COG1470@2|Bacteria,COG2755@2|Bacteria,2NRYN@2323|unclassified Bacteria	2|Bacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CBM_20,DUF1796,F5_F8_type_C,Lipase_GDSL_2
CMS3_k127_1644889_13	529818.AMSG_06622T0	8.576e-08	67.0	KOG1226@1|root,KOG1226@2759|Eukaryota	2759|Eukaryota	M	integrin-mediated signaling pathway	ITGBL1	GO:0005575,GO:0005623,GO:0005886,GO:0007155,GO:0008150,GO:0016020,GO:0022610,GO:0044464,GO:0071944	-	ko:K05719	ko04015,ko04145,ko04151,ko04360,ko04510,ko04512,ko04514,ko04530,ko04611,ko04670,ko04810,ko05100,ko05130,ko05131,ko05133,ko05140,ko05145,ko05165,ko05200,ko05205,ko05222,ko05410,ko05412,ko05414,map04015,map04145,map04151,map04360,map04510,map04512,map04514,map04530,map04611,map04670,map04810,map05100,map05130,map05131,map05133,map05140,map05145,map05165,map05200,map05205,map05222,map05410,map05412,map05414	-	-	-	ko00000,ko00001,ko04090,ko04131,ko04147,ko04516	-	-	-	EGF_2,Integrin_b_cyt,Integrin_beta
CMS3_k127_1662878_0	1123508.JH636439_gene616	1.712e-07	53.0	COG0816@1|root,COG0816@2|Bacteria,2J0EV@203682|Planctomycetes	203682|Planctomycetes	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS3_k127_1662878_1	411476.BACOVA_02806	0.0003471	54.0	COG3507@1|root,COG3507@2|Bacteria,4NGKH@976|Bacteroidetes,2FP3Q@200643|Bacteroidia,4AKEM@815|Bacteroidaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	abnA	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS3_k127_166755_0	1278073.MYSTI_03501	1.351e-104	350.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,2YU6V@29|Myxococcales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_166755_1	1129794.C427_2624	1.281e-28	121.0	COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,1S6EH@1236|Gammaproteobacteria,467ZF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS3_k127_1683578_9	1304872.JAGC01000003_gene3276	1.361e-08	64.0	COG3291@1|root,COG3291@2|Bacteria,1PHGX@1224|Proteobacteria,437VV@68525|delta/epsilon subdivisions,2X1BB@28221|Deltaproteobacteria,2MEPR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
CMS3_k127_1683578_7	1144275.COCOR_06299	4.849e-30	135.0	COG4733@1|root,COG4733@2|Bacteria,1QR73@1224|Proteobacteria,4387I@68525|delta/epsilon subdivisions,2X3HE@28221|Deltaproteobacteria,2YW3T@29|Myxococcales	28221|Deltaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1683578_4	324602.Caur_0299	3.611e-54	216.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_1683578_10	324602.Caur_0300	5.266e-05	54.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1683578_5	314230.DSM3645_11631	9.785e-54	196.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_1683578_1	1267533.KB906733_gene3472	2.488e-131	449.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_1683578_6	497964.CfE428DRAFT_3494	9.588e-49	186.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	omcN	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,GSu_C4xC__C2xCH,Paired_CXXCH_1,UVR
CMS3_k127_1683578_3	589865.DaAHT2_0880	2.519e-106	360.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MN5K@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_1683578_2	1142394.PSMK_11680	4.387e-122	409.0	COG1060@1|root,COG1060@2|Bacteria,2IXUS@203682|Planctomycetes	203682|Planctomycetes	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_1683578_0	886293.Sinac_1523	1.692e-188	606.0	COG1164@1|root,COG1164@2|Bacteria,2IYTJ@203682|Planctomycetes	203682|Planctomycetes	E	TIGRFAM oligoendopeptidase, M3 family	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS3_k127_1683578_8	1123290.AUDQ01000003_gene529	3.229e-24	120.0	COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli,26DPV@186818|Planococcaceae	91061|Bacilli	O	cytochrome c biogenesis	resC	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS3_k127_1683578_11	710393.HSUHS1_0649	0.0006531	51.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2YMXW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS3_k127_1693883_5	1173028.ANKO01000250_gene2398	3.577e-38	144.0	COG3153@1|root,COG3153@2|Bacteria,1G6EQ@1117|Cyanobacteria,1HCJA@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Acetyltransferase (GNAT) family	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
CMS3_k127_1693883_4	743719.PaelaDRAFT_3973	1.575e-61	222.0	COG2207@1|root,COG2207@2|Bacteria,1VIQW@1239|Firmicutes,4IR31@91061|Bacilli,26XKY@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_1693883_6	565045.NOR51B_1396	4.752e-38	156.0	29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,1SB4D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
CMS3_k127_1693883_3	394221.Mmar10_1145	2.659e-64	236.0	29KMP@1|root,307IZ@2|Bacteria,1REJ6@1224|Proteobacteria,2UAW7@28211|Alphaproteobacteria,43XXB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
CMS3_k127_1693883_1	1142394.PSMK_01150	5.505e-123	405.0	COG0492@1|root,COG0492@2|Bacteria,2IX3E@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_1693883_9	1142394.PSMK_06260	6.762e-13	79.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_1693883_12	1122207.MUS1_11270	1.744e-05	53.0	2BKRI@1|root,32F7F@2|Bacteria,1Q0G7@1224|Proteobacteria,1STIC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1693883_0	344747.PM8797T_19864	2.221e-166	537.0	COG0147@1|root,COG0147@2|Bacteria,2IX6Q@203682|Planctomycetes	203682|Planctomycetes	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS3_k127_1693883_8	1121936.AUHI01000018_gene640	2.991e-29	123.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli	91061|Bacilli	S	protein with conserved CXXC pairs	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
CMS3_k127_1693883_2	886293.Sinac_6415	4.31e-115	381.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
CMS3_k127_1693883_7	1192034.CAP_5016	1.232e-36	147.0	COG0745@1|root,COG0745@2|Bacteria,1NUNK@1224|Proteobacteria,43CMR@68525|delta/epsilon subdivisions,2X7UV@28221|Deltaproteobacteria,2Z3I4@29|Myxococcales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Response_reg
CMS3_k127_1693883_11	794903.OPIT5_12790	6.032e-07	63.0	2DN50@1|root,32VJ4@2|Bacteria,46TKZ@74201|Verrucomicrobia,3K748@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS3_k127_1693883_10	247490.KSU1_C0524	2.515e-12	79.0	COG3225@1|root,COG3225@2|Bacteria,2J05Q@203682|Planctomycetes	203682|Planctomycetes	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS3_k127_171011_2	714943.Mucpa_7131	6.576e-29	122.0	COG3695@1|root,COG3695@2|Bacteria,4NZHS@976|Bacteroidetes,1IZ68@117747|Sphingobacteriia	976|Bacteroidetes	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
CMS3_k127_171011_0	395493.BegalDRAFT_1262	1.711e-78	279.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CMS3_k127_171011_1	395493.BegalDRAFT_1263	1.159e-53	205.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CMS3_k127_1751082_3	314230.DSM3645_09877	2.036e-09	61.0	COG0291@1|root,COG0291@2|Bacteria,2J1B4@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS3_k127_1751082_0	314230.DSM3645_09872	9.139e-34	133.0	COG0292@1|root,COG0292@2|Bacteria,2J02D@203682|Planctomycetes	203682|Planctomycetes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS3_k127_1751082_1	660470.Theba_0308	2.346e-31	135.0	COG2035@1|root,COG2035@2|Bacteria,2GDA0@200918|Thermotogae	200918|Thermotogae	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
CMS3_k127_1751082_2	314230.DSM3645_22786	1.779e-10	70.0	COG2982@1|root,COG2982@2|Bacteria,2IYVI@203682|Planctomycetes	203682|Planctomycetes	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
CMS3_k127_1762803_2	144197.XP_008304632.1	8.395e-11	68.0	2C27E@1|root,2S2R7@2759|Eukaryota,3A0FP@33154|Opisthokonta,3BQ2T@33208|Metazoa,3D6FG@33213|Bilateria,48EFC@7711|Chordata,49B85@7742|Vertebrata,4A37J@7898|Actinopterygii	33208|Metazoa	S	AhpC/TSA antioxidant enzyme	sell	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
CMS3_k127_1762803_4	391600.ABRU01000003_gene1623	0.0009593	44.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2KGSV@204458|Caulobacterales	204458|Caulobacterales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_1762803_0	243090.RB9948	1.629e-36	143.0	COG2318@1|root,COG2318@2|Bacteria,2J046@203682|Planctomycetes	203682|Planctomycetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_1762803_1	768710.DesyoDRAFT_0470	6.729e-19	93.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS3_k127_1762803_3	267608.RSc0609	2.186e-08	59.0	28KDQ@1|root,2ZAX1@2|Bacteria,1QY70@1224|Proteobacteria,2WHCH@28216|Betaproteobacteria,1KGBB@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1763643_0	575540.Isop_1648	1.723e-79	297.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_1766722_0	391937.NA2_04042	1.278e-40	155.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,43HF6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS3_k127_1766722_1	1122919.KB905650_gene1647	7.942e-27	117.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1766722_2	1121087.AUCK01000034_gene1551	0.0001153	52.0	COG1664@1|root,COG1664@2|Bacteria,1UIJB@1239|Firmicutes,4ITGM@91061|Bacilli,1ZSBW@1386|Bacillus	91061|Bacilli	M	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
CMS3_k127_1769423_2	1210884.HG799467_gene13285	1.681e-115	383.0	COG1363@1|root,COG1363@2|Bacteria,2IXMY@203682|Planctomycetes	203682|Planctomycetes	G	COG1363 Cellulase M and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS3_k127_1769423_5	1142394.PSMK_27340	2.631e-83	300.0	COG2208@1|root,COG4936@1|root,COG2208@2|Bacteria,COG4936@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
CMS3_k127_1769423_0	886293.Sinac_3050	9.428e-313	989.0	COG0495@1|root,COG0495@2|Bacteria,2IX36@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS3_k127_1769423_11	411464.DESPIG_01229	2.343e-18	94.0	COG1437@1|root,COG1437@2|Bacteria,1N326@1224|Proteobacteria,42U83@68525|delta/epsilon subdivisions,2WQQR@28221|Deltaproteobacteria,2MBY3@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
CMS3_k127_1769423_7	330214.NIDE2543	7.443e-77	269.0	COG0616@1|root,COG0616@2|Bacteria,3J13W@40117|Nitrospirae	40117|Nitrospirae	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_1769423_10	1463934.JOCF01000038_gene2247	3.026e-26	113.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
CMS3_k127_1769423_9	474922.ELA27783	3.941e-36	157.0	COG2866@1|root,KOG2650@2759|Eukaryota,38DUK@33154|Opisthokonta,3NUYK@4751|Fungi,3QKG5@4890|Ascomycota,216C0@147550|Sordariomycetes,1F0ND@1028384|Glomerellales	4751|Fungi	O	Carboxypeptidase	MCPA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Propep_M14
CMS3_k127_1769423_6	521674.Plim_2359	6.637e-78	273.0	COG3494@1|root,COG3494@2|Bacteria,2IXGX@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
CMS3_k127_1769423_4	1125863.JAFN01000001_gene3410	3.067e-85	294.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS3_k127_1769423_1	59374.Fisuc_0534	2.035e-123	413.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.12	ko:K00694,ko:K00786	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_tranf_2_3
CMS3_k127_1769423_8	237368.SCABRO_01833	2.321e-37	162.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.7.8.20	ko:K01002,ko:K20534	ko01100,map01100	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	GT87,Glycos_transf_2
CMS3_k127_1769423_3	246197.MXAN_3159	3.1e-99	338.0	COG0308@1|root,COG0308@2|Bacteria,1NQIW@1224|Proteobacteria,4391T@68525|delta/epsilon subdivisions,2X47D@28221|Deltaproteobacteria,2YYES@29|Myxococcales	28221|Deltaproteobacteria	E	Phospholipase B	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_B
CMS3_k127_177388_0	886293.Sinac_3058	1.663e-161	522.0	COG1249@1|root,COG1249@2|Bacteria,2IY39@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_177388_1	298653.Franean1_1216	1.883e-92	320.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4EUMC@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_1846445_1	1254432.SCE1572_02825	1.372e-136	442.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2YUAI@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9
CMS3_k127_1846445_0	1499967.BAYZ01000195_gene3106	3.979e-140	463.0	COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	MA20_19960	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1847507_0	574376.BAMA_20505	9.572e-59	211.0	COG4912@1|root,COG4912@2|Bacteria,1TSAW@1239|Firmicutes,4HM25@91061|Bacilli,1ZDKZ@1386|Bacillus	91061|Bacilli	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS3_k127_1847507_3	585543.HMPREF0969_01392	2.145e-13	84.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,2FNXZ@200643|Bacteroidia,4APGM@815|Bacteroidaceae	976|Bacteroidetes	P	COG2382 Enterochelin esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
CMS3_k127_1847507_1	497964.CfE428DRAFT_0769	8.142e-33	147.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_1876287_0	1232410.KI421418_gene2408	1.562e-176	616.0	COG3507@1|root,COG4733@1|root,COG3507@2|Bacteria,COG4733@2|Bacteria,1RDH5@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349
CMS3_k127_1876287_7	243231.GSU2715	1.053e-09	74.0	COG2931@1|root,COG3055@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,1MU7T@1224|Proteobacteria,42UQ7@68525|delta/epsilon subdivisions,2WR0J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CMS3_k127_1876287_3	489825.LYNGBM3L_47330	2.283e-32	149.0	COG2706@1|root,COG3507@1|root,COG5492@1|root,COG2706@2|Bacteria,COG3507@2|Bacteria,COG5492@2|Bacteria,1GQES@1117|Cyanobacteria	1117|Cyanobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349
CMS3_k127_1876287_9	404589.Anae109_1829	0.0001411	57.0	COG2374@1|root,COG2374@2|Bacteria,1RA34@1224|Proteobacteria,42XZM@68525|delta/epsilon subdivisions,2WT9C@28221|Deltaproteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1876287_6	1121396.KB892946_gene2917	8.861e-10	72.0	COG0823@1|root,COG3291@1|root,COG3591@1|root,COG4676@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3591@2|Bacteria,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	Germane,Gmad1
CMS3_k127_1876287_2	1385935.N836_20445	7.463e-39	166.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
CMS3_k127_1876287_8	7668.SPU_009755-tr	7.52e-05	56.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3D261@33213|Bilateria	33208|Metazoa	T	Thrombospondin type 3 repeat	-	-	-	ko:K04659	ko04145,ko04151,ko04510,ko04512,ko05144,ko05165,map04145,map04151,map04510,map04512,map05144,map05165	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04147,ko04516	-	-	-	EGF_CA,F5_F8_type_C,TSP_3,TSP_C
CMS3_k127_1876287_4	483219.LILAB_25790	3.304e-27	130.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M36,Peptidase_M6
CMS3_k127_1876287_1	1121396.KB892946_gene2917	1.829e-60	239.0	COG0823@1|root,COG3291@1|root,COG3591@1|root,COG4676@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3591@2|Bacteria,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	Germane,Gmad1
CMS3_k127_1876287_5	96561.Dole_3116	1.902e-10	75.0	COG0823@1|root,COG0823@2|Bacteria,1R7MY@1224|Proteobacteria,42WWM@68525|delta/epsilon subdivisions,2WSNJ@28221|Deltaproteobacteria	1224|Proteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PD40
CMS3_k127_1895843_4	1210884.HG799464_gene10830	1.582e-74	263.0	COG0352@1|root,COG0352@2|Bacteria,2IY16@203682|Planctomycetes	203682|Planctomycetes	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Clp_N,TMP-TENI
CMS3_k127_1895843_0	867845.KI911784_gene1788	3.377e-313	973.0	COG2766@1|root,COG2766@2|Bacteria,2G65T@200795|Chloroflexi,3756U@32061|Chloroflexia	32061|Chloroflexia	T	PFAM PrkA serine kinase	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
CMS3_k127_1895843_2	290397.Adeh_1229	1.008e-136	444.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,42PDK@68525|delta/epsilon subdivisions,2WJKJ@28221|Deltaproteobacteria,2YTX7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
CMS3_k127_1895843_1	521674.Plim_2992	1.594e-181	590.0	COG2719@1|root,COG2719@2|Bacteria,2IXSH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
CMS3_k127_1895843_7	1167006.UWK_02191	3.941e-33	133.0	COG1607@1|root,COG1607@2|Bacteria	2|Bacteria	I	acyl-coa hydrolase	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
CMS3_k127_1895843_6	192875.XP_004364712.1	2.342e-66	239.0	COG0463@1|root,KOG2978@2759|Eukaryota,38E12@33154|Opisthokonta	33154|Opisthokonta	M	dolichyl-phosphate beta-D-mannosyltransferase activity	-	GO:0000030,GO:0003674,GO:0003824,GO:0004582,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0006464,GO:0006486,GO:0006487,GO:0006488,GO:0006490,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009247,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0019637,GO:0019867,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0070085,GO:0071704,GO:0071944,GO:0090407,GO:0097502,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_1895843_5	344747.PM8797T_16615	3.003e-73	263.0	COG0767@1|root,COG0767@2|Bacteria,2IX01@203682|Planctomycetes	203682|Planctomycetes	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_1895843_3	1379698.RBG1_1C00001G0979	6.519e-79	271.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_1895843_8	445970.ALIPUT_01150	1.154e-05	57.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,2FPK9@200643|Bacteroidia,22UF5@171550|Rikenellaceae	976|Bacteroidetes	Q	virulence factor Mce family protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_1909942_1	234267.Acid_4393	1.083e-84	287.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1909942_3	876269.ARWA01000001_gene3613	4.5e-42	165.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
CMS3_k127_1909942_0	243090.RB13330	4.192e-148	489.0	COG0457@1|root,COG5305@1|root,COG0457@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1909942_2	497964.CfE428DRAFT_1800	1.265e-58	216.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_1910309_12	1267535.KB906767_gene4499	2.012e-41	157.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_1910309_2	1267533.KB906733_gene3472	1.561e-137	466.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_1910309_17	1267533.KB906741_gene652	1.28e-21	99.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	ysfE	-	2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5	ko:K00941,ko:K01724,ko:K01759,ko:K07032,ko:K08234	ko00620,ko00730,ko00790,ko01100,map00620,map00730,map00790,map01100	M00127	R02530,R03471,R04509,R04734	RC00002,RC00004,RC00017,RC00740,RC01208	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
CMS3_k127_1910309_4	330214.NIDE0473	6.499e-131	432.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
CMS3_k127_1910309_6	243090.RB13271	8.382e-109	361.0	COG1181@1|root,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_1910309_0	880073.Calab_2105	4.053e-160	529.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acd	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249,ko:K20035	ko00071,ko00280,ko00410,ko00640,ko00650,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map00920,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R11130	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246,RC03363	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS3_k127_1910309_5	545694.TREPR_1266	1.77e-111	370.0	COG2025@1|root,COG2025@2|Bacteria,2J5XR@203691|Spirochaetes	203691|Spirochaetes	C	Electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS3_k127_1910309_7	880073.Calab_2103	1.375e-100	336.0	COG2086@1|root,COG2086@2|Bacteria,2NP4J@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_1910309_10	1192034.CAP_5031	2.618e-67	245.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,42ST6@68525|delta/epsilon subdivisions,2WPEM@28221|Deltaproteobacteria,2YWW2@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_1910309_14	448385.sce6861	9.727e-36	153.0	2DQ41@1|root,334MP@2|Bacteria,1QWJG@1224|Proteobacteria,43CUB@68525|delta/epsilon subdivisions,2X81Y@28221|Deltaproteobacteria,2Z1U1@29|Myxococcales	1224|Proteobacteria	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1
CMS3_k127_1910309_19	926560.KE387023_gene2506	1.952e-11	73.0	2AYAM@1|root,33ACG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1910309_21	1239415.CM001837_gene2137	0.0009976	49.0	2EFT5@1|root,339J5@2|Bacteria,4NZGJ@976|Bacteroidetes,1I6IW@117743|Flavobacteriia,37FF2@326319|Dokdonia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1910309_3	398767.Glov_2292	4.729e-136	462.0	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,42VEM@68525|delta/epsilon subdivisions,2WRGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1910309_13	880073.Calab_1267	7.007e-40	158.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Paired_CXXCH_1
CMS3_k127_1910309_11	1192034.CAP_3514	3.204e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_1910309_8	1267533.KB906733_gene3472	1.459e-83	314.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_1910309_9	102129.Lepto7375DRAFT_2687	4.951e-72	277.0	COG2319@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3629@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NACHT,NB-ARC,Pentapeptide,WD40
CMS3_k127_1910309_18	502025.Hoch_6795	4.171e-16	94.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_1910309_15	1347342.BN863_18710	1.948e-32	142.0	COG3250@1|root,COG3250@2|Bacteria,4NGEN@976|Bacteroidetes,1HYS2@117743|Flavobacteriia	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C
CMS3_k127_1910309_1	247633.GP2143_05970	7.195e-159	514.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS3_k127_1910309_16	5762.XP_002670183.1	4.379e-25	120.0	KOG1217@1|root,KOG1217@2759|Eukaryota	2759|Eukaryota	O	calcium ion binding	egas-3	-	-	-	-	-	-	-	-	-	-	-	ASC,DSL,EGF,EGF_CA
CMS3_k127_1910309_20	1535422.ND16A_2156	0.0004649	49.0	COG1800@1|root,COG5184@1|root,COG1800@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_5,CHU_C,CW_binding_2,Cadherin-like,CarboxypepD_reg,Laminin_G_3,SLH
CMS3_k127_1911549_1	44689.DDB0232407	0.0002758	55.0	2D42B@1|root,2STKH@2759|Eukaryota,3XGC8@554915|Amoebozoa	554915|Amoebozoa	S	PA14 domain	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Dicty_CTDC,PA14
CMS3_k127_1911549_0	1121396.KB893120_gene3067	1.081e-73	253.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1918439_0	1131269.AQVV01000024_gene2355	7.576e-97	331.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_1918439_5	1123274.KB899407_gene236	1.782e-56	202.0	COG0252@1|root,COG0252@2|Bacteria	2|Bacteria	EJ	asparaginase activity	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS3_k127_1918439_4	1254432.SCE1572_38850	9.096e-66	246.0	COG0564@1|root,COG1092@1|root,COG0564@2|Bacteria,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2WPIN@28221|Deltaproteobacteria,2Z02J@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PseudoU_synth_2
CMS3_k127_1918439_13	756272.Plabr_1950	3.881e-11	76.0	COG1413@1|root,COG3391@1|root,COG1413@2|Bacteria,COG3391@2|Bacteria,2IXTT@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_1918439_8	1265502.KB905962_gene362	8.884e-30	132.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,4ABUM@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS3_k127_1918439_10	166318.Syn8016DRAFT_2575	4.423e-22	99.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1H14U@1129|Synechococcus	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS3_k127_1918439_9	515635.Dtur_0722	4.51e-23	115.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS3_k127_1918439_11	7209.EFO25409.2	1.249e-19	101.0	COG3914@1|root,KOG4626@2759|Eukaryota,38EM5@33154|Opisthokonta,3BC3N@33208|Metazoa,3CWN6@33213|Bilateria,40AIB@6231|Nematoda,1KTY3@119089|Chromadorea	33208|Metazoa	GOT	Glycosyl transferase family 41	OGT	GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
CMS3_k127_1918439_2	575540.Isop_1149	2.655e-70	246.0	COG1216@1|root,COG1216@2|Bacteria,2J55H@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1918439_6	1123508.JH636439_gene614	5.979e-54	209.0	2C7TA@1|root,2Z9TR@2|Bacteria,2IXIJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1918439_12	1142394.PSMK_21090	4.092e-15	81.0	2EAFJ@1|root,334IY@2|Bacteria,2J12W@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
CMS3_k127_1918439_7	1142394.PSMK_31720	3.027e-33	145.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_1918439_3	1157490.EL26_01420	8.591e-70	246.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,279RJ@186823|Alicyclobacillaceae	91061|Bacilli	EH	Amino-transferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_1918439_1	1121921.KB898706_gene2960	9.826e-88	312.0	COG3391@1|root,COG5184@1|root,COG5276@1|root,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,NHL
CMS3_k127_1921647_2	886293.Sinac_5591	2.587e-24	106.0	COG0736@1|root,COG0736@2|Bacteria,2IZSD@203682|Planctomycetes	203682|Planctomycetes	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_1921647_0	1142394.PSMK_16820	3.95e-177	584.0	COG0210@1|root,COG0210@2|Bacteria,2IWTI@203682|Planctomycetes	203682|Planctomycetes	L	COG0210 Superfamily I DNA and RNA	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_1921647_1	1120950.KB892759_gene6279	3.104e-99	341.0	COG0836@1|root,COG0836@2|Bacteria,2GIRM@201174|Actinobacteria,4DPTJ@85009|Propionibacteriales	201174|Actinobacteria	M	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS3_k127_1921647_3	215803.DB30_2905	3.87e-23	104.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS3_k127_1933910_2	1123242.JH636435_gene985	1.072e-28	123.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1933910_1	1047013.AQSP01000123_gene1525	1.041e-52	206.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_1933910_3	1236959.BAMT01000002_gene1881	3.253e-25	112.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2VMVW@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
CMS3_k127_1933910_0	143224.JQMD01000002_gene2489	2.269e-150	484.0	COG0500@1|root,COG2226@2|Bacteria,4NE69@976|Bacteroidetes,1HZ10@117743|Flavobacteriia	976|Bacteroidetes	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_1933910_4	324602.Caur_0299	1.618e-16	93.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_1964568_0	886293.Sinac_5589	8.064e-216	706.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,2IY53@203682|Planctomycetes	203682|Planctomycetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS3_k127_1964979_0	1167006.UWK_01363	1.946e-307	974.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MIEI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_1964979_1	1167006.UWK_01362	4.567e-45	174.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria,2MIMX@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_1973729_4	1382306.JNIM01000001_gene1809	5.434e-34	137.0	COG1225@1|root,COG1225@2|Bacteria,2G6XD@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1973729_5	644966.Tmar_0494	1.365e-17	90.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
CMS3_k127_1973729_2	525904.Tter_0879	1.803e-90	306.0	COG0501@1|root,COG0501@2|Bacteria,2NP1V@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the peptidase M48B family	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS3_k127_1973729_3	266117.Rxyl_2532	1.401e-67	239.0	COG0614@1|root,COG0614@2|Bacteria,2GYJE@201174|Actinobacteria,4CTJ1@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
CMS3_k127_1973729_6	59931.WH7805_12288	6.043e-13	79.0	COG0265@1|root,COG0265@2|Bacteria,1G17C@1117|Cyanobacteria,1H46N@1129|Synechococcus	1117|Cyanobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	hhoA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_1973729_1	1522072.IL54_1959	5.578e-150	490.0	COG1629@1|root,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTN6@28211|Alphaproteobacteria,2K0KK@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_1973729_0	702113.PP1Y_AT13112	1.033e-178	572.0	COG1506@1|root,COG2936@1|root,COG1506@2|Bacteria,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,2K0WA@204457|Sphingomonadales	204457|Sphingomonadales	E	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_1987010_7	589865.DaAHT2_1865	3.819e-12	71.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MHQU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS3_k127_1987010_5	530564.Psta_3659	1.898e-71	248.0	COG0571@1|root,COG0571@2|Bacteria,2IYW1@203682|Planctomycetes	203682|Planctomycetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS3_k127_1987010_0	1142394.PSMK_26660	4.951e-228	721.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,2IXPK@203682|Planctomycetes	203682|Planctomycetes	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_1987010_4	1142394.PSMK_21860	4.467e-82	284.0	COG0568@1|root,COG0568@2|Bacteria,2IYCB@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_1987010_3	215803.DB30_5113	9.504e-89	311.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS3_k127_1987010_2	215803.DB30_4900	3.774e-133	443.0	COG1680@1|root,COG1680@2|Bacteria,1PEI7@1224|Proteobacteria,43DSW@68525|delta/epsilon subdivisions,2X8V3@28221|Deltaproteobacteria,2Z0DE@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1987010_1	314230.DSM3645_18261	8.936e-173	552.0	COG1520@1|root,COG1520@2|Bacteria,2IXD2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_1987010_8	43759.JNWK01000037_gene4506	1.254e-07	61.0	COG1141@1|root,COG1141@2|Bacteria,2IR4H@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CMS3_k127_1987010_6	765910.MARPU_12465	9.629e-67	233.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1WXDV@135613|Chromatiales	135613|Chromatiales	K	response regulator receiver	-	-	-	ko:K13041	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_1987010_10	1123277.KB893205_gene6321	0.0004584	53.0	COG0457@1|root,COG0457@2|Bacteria,4PMN3@976|Bacteroidetes	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_1990596_10	1206743.BAGM01000082_gene4162	9.84e-05	52.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4G0IS@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_1990596_8	439235.Dalk_1630	1.57e-34	135.0	COG1146@1|root,COG1146@2|Bacteria,1N0QV@1224|Proteobacteria,42U2Z@68525|delta/epsilon subdivisions,2WR58@28221|Deltaproteobacteria,2MM2N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
CMS3_k127_1990596_2	204669.Acid345_1810	1.128e-162	522.0	COG0674@1|root,COG0674@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS3_k127_1990596_3	765912.Thimo_0251	3.055e-119	395.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1WXDP@135613|Chromatiales	135613|Chromatiales	C	PFAM thiamine pyrophosphate enzyme	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_1990596_7	404589.Anae109_1896	8.436e-51	186.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions,2WMQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS3_k127_1990596_9	1069080.KB913028_gene1540	1.353e-19	91.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes	1239|Firmicutes	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
CMS3_k127_1990596_0	1123371.ATXH01000023_gene926	6.393e-212	692.0	COG1148@1|root,COG1148@2|Bacteria,2GHRW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
CMS3_k127_1990596_6	429009.Adeg_1784	1.751e-52	190.0	COG1894@1|root,COG1908@1|root,COG1894@2|Bacteria,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
CMS3_k127_1990596_4	335543.Sfum_1176	1.069e-86	300.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS3_k127_1990596_5	1121403.AUCV01000020_gene3109	1.21e-82	278.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
CMS3_k127_1990596_1	1121403.AUCV01000020_gene3109	9.715e-179	569.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
CMS3_k127_1996225_5	1122971.BAME01000075_gene5104	3.687e-06	61.0	COG1225@1|root,COG1225@2|Bacteria,4P08Q@976|Bacteroidetes,2FWN9@200643|Bacteroidia,23284@171551|Porphyromonadaceae	976|Bacteroidetes	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CMS3_k127_1996225_4	1122985.HMPREF1991_01244	4.074e-07	64.0	COG1225@1|root,COG1225@2|Bacteria,4P08Q@976|Bacteroidetes,2FWN9@200643|Bacteroidia	976|Bacteroidetes	O	Antioxidant, AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CMS3_k127_1996225_3	240015.ACP_2145	1.354e-07	66.0	COG0526@1|root,COG0526@2|Bacteria,3Y5DD@57723|Acidobacteria,2JJQP@204432|Acidobacteriia	204432|Acidobacteriia	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1996225_0	237368.SCABRO_01224	1.342e-21	112.0	2DBYC@1|root,2ZBUF@2|Bacteria,2IZ15@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS3_k127_1996225_1	56780.SYN_02031	3.574e-19	95.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42U6G@68525|delta/epsilon subdivisions,2WQDR@28221|Deltaproteobacteria,2MQQ1@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195	PgpA
CMS3_k127_1996225_2	42256.RradSPS_0274	1.105e-13	78.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4CQXP@84995|Rubrobacteria	84995|Rubrobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1996225_6	742738.HMPREF9460_02287	1.725e-05	53.0	COG5662@1|root,COG5662@2|Bacteria,1VHF3@1239|Firmicutes,24SVU@186801|Clostridia,269PP@186813|unclassified Clostridiales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_1996262_7	237368.SCABRO_03064	7.453e-19	89.0	COG0438@1|root,COG0438@2|Bacteria,2IZ1G@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1996262_5	1304880.JAGB01000001_gene818	7.494e-38	151.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS3_k127_1996262_1	1142394.PSMK_22020	2.125e-115	391.0	COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,2IYBJ@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,PAS_4,Response_reg
CMS3_k127_1996262_0	237368.SCABRO_02223	9.691e-139	450.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_1996262_2	237368.SCABRO_01880	5.167e-109	362.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_1996262_8	237368.SCABRO_01881	5.08e-17	95.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1996262_3	1123242.JH636434_gene5412	5.208e-60	222.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS3_k127_1996262_4	344747.PM8797T_13987	1.748e-41	168.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2IYZ1@203682|Planctomycetes	203682|Planctomycetes	A	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_1996262_6	344747.PM8797T_13992	1.307e-37	161.0	COG0457@1|root,COG0457@2|Bacteria,2IWZ3@203682|Planctomycetes	203682|Planctomycetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS3_k127_2002455_11	666685.R2APBS1_1294	0.0001189	50.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1X5FH@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
CMS3_k127_2002455_8	349741.Amuc_1061	2.269e-29	134.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
CMS3_k127_2002455_4	935948.KE386494_gene944	1.764e-99	340.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_2002455_0	485915.Dret_1750	1.355e-282	890.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
CMS3_k127_2002455_6	1192034.CAP_7929	1.519e-44	186.0	COG1404@1|root,COG3147@1|root,COG1404@2|Bacteria,COG3147@2|Bacteria	2|Bacteria	S	peptidoglycan binding	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	B_lectin,SseB
CMS3_k127_2002455_1	1121441.AUCX01000017_gene2004	7.172e-170	563.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
CMS3_k127_2002455_3	595460.RRSWK_03709	7.733e-136	459.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_2002455_5	596152.DesU5LDRAFT_2631	1.486e-63	241.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_2002455_7	221288.JH992901_gene3772	5.051e-39	153.0	COG1586@1|root,COG1586@2|Bacteria,1G5QZ@1117|Cyanobacteria,1JMTT@1189|Stigonemataceae	1117|Cyanobacteria	E	S-adenosylmethionine decarboxylase	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
CMS3_k127_2002455_2	1173028.ANKO01000124_gene2878	1.005e-148	475.0	COG0421@1|root,COG0421@2|Bacteria,1G36Y@1117|Cyanobacteria,1H85B@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
CMS3_k127_2002455_9	1121285.AUFK01000018_gene763	1.55e-28	126.0	COG2207@1|root,COG2207@2|Bacteria,4NHA5@976|Bacteroidetes,1I053@117743|Flavobacteriia,3ZUEU@59732|Chryseobacterium	976|Bacteroidetes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_2002455_10	521045.Kole_0659	1.568e-28	126.0	COG1917@1|root,COG3255@1|root,COG1917@2|Bacteria,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Arg_Hydrox,Cupin_2,SCP2
CMS3_k127_2003185_0	627192.SLG_34920	1.396e-84	317.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2UNZR@28211|Alphaproteobacteria,2KECI@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS3_k127_2006455_7	272568.GDI1551	1.495e-06	49.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2U1DA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CMS3_k127_2006455_5	1123393.KB891329_gene1074	3.774e-13	81.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria	1224|Proteobacteria	M	TIGRFAM YD repeat protein	wapA	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
CMS3_k127_2006455_3	927658.AJUM01000044_gene617	4.065e-26	123.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,2FQDN@200643|Bacteroidia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
CMS3_k127_2006455_1	10090.ENSMUSP00000093771	4.758e-41	170.0	COG2866@1|root,KOG2650@2759|Eukaryota,38DUK@33154|Opisthokonta,3BA6U@33208|Metazoa,3CUQS@33213|Bilateria,481VD@7711|Chordata,490AY@7742|Vertebrata,3JAWZ@40674|Mammalia,35CDI@314146|Euarchontoglires,4Q6WI@9989|Rodentia	33208|Metazoa	O	metallocarboxypeptidase activity	CPA2	GO:0001990,GO:0001991,GO:0002002,GO:0003008,GO:0003013,GO:0003044,GO:0003073,GO:0003081,GO:0003330,GO:0003331,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0006950,GO:0007039,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008285,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010755,GO:0010757,GO:0010817,GO:0010955,GO:0012505,GO:0016787,GO:0019222,GO:0019538,GO:0022603,GO:0030133,GO:0030162,GO:0030163,GO:0030193,GO:0030194,GO:0030195,GO:0031012,GO:0031323,GO:0031324,GO:0031410,GO:0031982,GO:0032101,GO:0032102,GO:0032103,GO:0032268,GO:0032269,GO:0032501,GO:0032879,GO:0042127,GO:0042730,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045861,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050818,GO:0050819,GO:0050820,GO:0050878,GO:0050886,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051917,GO:0051918,GO:0060102,GO:0060255,GO:0061041,GO:0061045,GO:0062023,GO:0065007,GO:0065008,GO:0070011,GO:0070613,GO:0071704,GO:0080090,GO:0080134,GO:0090303,GO:0097708,GO:0140096,GO:1900046,GO:1900047,GO:1900048,GO:1901564,GO:1901565,GO:1901575,GO:1903034,GO:1903035,GO:1903036,GO:1903053,GO:1903055,GO:1903317,GO:1903318,GO:1903530,GO:1903532,GO:2000026,GO:2000027,GO:2000345,GO:2000346	2.7.11.17,3.4.17.1,3.4.17.15,3.4.17.2,3.4.17.20	ko:K01291,ko:K01298,ko:K01300,ko:K04515,ko:K08637,ko:K08779,ko:K08780,ko:K08781	ko04012,ko04020,ko04024,ko04066,ko04114,ko04217,ko04261,ko04310,ko04360,ko04610,ko04614,ko04713,ko04720,ko04722,ko04725,ko04728,ko04740,ko04745,ko04750,ko04911,ko04912,ko04916,ko04921,ko04922,ko04925,ko04934,ko04971,ko04972,ko04974,ko05031,ko05152,ko05200,ko05205,ko05214,map04012,map04020,map04024,map04066,map04114,map04217,map04261,map04310,map04360,map04610,map04614,map04713,map04720,map04722,map04725,map04728,map04740,map04745,map04750,map04911,map04912,map04916,map04921,map04922,map04925,map04934,map04971,map04972,map04974,map05031,map05152,map05200,map05205,map05214	-	-	-	ko00000,ko00001,ko01000,ko01001,ko01002,ko03110	-	-	-	Peptidase_M14,Propep_M14,ShK
CMS3_k127_2006455_6	502025.Hoch_6539	4.019e-07	64.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2006455_4	237368.SCABRO_01739	8.374e-15	87.0	2DBYC@1|root,2ZBUF@2|Bacteria,2IZ15@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS3_k127_2006455_2	530564.Psta_0650	1.604e-34	154.0	COG1470@1|root,COG1470@2|Bacteria,2IZ1T@203682|Planctomycetes	203682|Planctomycetes	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2006455_0	314230.DSM3645_21574	2.015e-117	390.0	COG0029@1|root,COG0029@2|Bacteria,2IY30@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_2007435_1	234267.Acid_5023	3.896e-20	107.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2007435_0	945713.IALB_0021	1.114e-30	142.0	COG1404@1|root,COG3303@1|root,COG1404@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,Cytochrom_C552,Cytochrome_C554,FlgD_ig,Paired_CXXCH_1,VCBS
CMS3_k127_2007435_3	449447.MAE_14090	3.146e-15	91.0	COG3391@1|root,COG3391@2|Bacteria,1G499@1117|Cyanobacteria	1117|Cyanobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,VPEP
CMS3_k127_2007435_2	443143.GM18_0593	6.039e-19	102.0	COG4733@1|root,COG4932@1|root,COG4733@2|Bacteria,COG4932@2|Bacteria,1RHT8@1224|Proteobacteria,430B7@68525|delta/epsilon subdivisions,2WVNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Fibronectin type 3 domain	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
CMS3_k127_2024785_34	247490.KSU1_B0317	1.872e-09	62.0	COG0709@1|root,COG0709@2|Bacteria,2IZ3Y@203682|Planctomycetes	203682|Planctomycetes	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS3_k127_2024785_18	1217720.ALOX01000004_gene4052	3.171e-56	207.0	COG0596@1|root,COG0596@2|Bacteria,1MW2P@1224|Proteobacteria,2TSS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	MA20_32265	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_2024785_3	1353529.M899_0353	5.462e-126	415.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2MSP8@213481|Bdellovibrionales,2WJTS@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
CMS3_k127_2024785_27	552811.Dehly_0191	1.366e-16	85.0	2EQ22@1|root,33HNG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2024785_37	744980.TRICHSKD4_0131	7.591e-08	57.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS3_k127_2024785_10	1120973.AQXL01000127_gene2746	1.272e-93	327.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,2788X@186823|Alicyclobacillaceae	91061|Bacilli	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS3_k127_2024785_22	1121930.AQXG01000005_gene635	3.39e-37	143.0	COG0386@1|root,COG0386@2|Bacteria,4NM6G@976|Bacteroidetes,1IS94@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CMS3_k127_2024785_36	161934.XP_010670824.1	9.354e-09	59.0	COG0386@1|root,KOG1651@2759|Eukaryota,37K04@33090|Viridiplantae,3G9CQ@35493|Streptophyta	35493|Streptophyta	O	Belongs to the glutathione peroxidase family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009941,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0080167	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CMS3_k127_2024785_1	247490.KSU1_C0165	1.605e-169	552.0	COG1032@1|root,COG1032@2|Bacteria,2IXAT@203682|Planctomycetes	203682|Planctomycetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_2024785_35	237368.SCABRO_03851	8.569e-09	66.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_2024785_6	575540.Isop_0232	2.026e-103	349.0	COG0823@1|root,COG0823@2|Bacteria,2IXGY@203682|Planctomycetes	203682|Planctomycetes	U	Periplasmic component of the Tol biopolymer transport	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,PDZ_2,Peptidase_M28
CMS3_k127_2024785_17	593750.Metfor_2855	4.531e-59	214.0	COG2518@1|root,arCOG00976@2157|Archaea,2XTRM@28890|Euryarchaeota,2N9U4@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_2024785_16	517418.Ctha_1710	3.707e-59	216.0	COG1912@1|root,COG1912@2|Bacteria,1FDZ8@1090|Chlorobi	1090|Chlorobi	M	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CMS3_k127_2024785_21	1142394.PSMK_07420	6.166e-42	177.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	TPR_12,TPR_16,TPR_6,TPR_8,cNMP_binding
CMS3_k127_2024785_19	1142394.PSMK_21790	9.261e-51	193.0	COG4191@1|root,COG4191@2|Bacteria,2IZJ4@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_2024785_4	404589.Anae109_2442	8.759e-117	391.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2024785_26	530564.Psta_4337	3.192e-17	87.0	COG1815@1|root,COG1815@2|Bacteria,2J0V3@203682|Planctomycetes	203682|Planctomycetes	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
CMS3_k127_2024785_25	530564.Psta_4338	2.502e-21	98.0	COG1558@1|root,COG1558@2|Bacteria,2J09G@203682|Planctomycetes	203682|Planctomycetes	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS3_k127_2024785_30	1131269.AQVV01000003_gene702	3.115e-12	70.0	COG1677@1|root,COG1677@2|Bacteria	2|Bacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
CMS3_k127_2024785_32	1231241.Mc24_01059	6.35e-11	75.0	COG1766@1|root,COG1766@2|Bacteria,2GCH8@200918|Thermotogae	200918|Thermotogae	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
CMS3_k127_2024785_5	1142394.PSMK_21730	5.933e-113	375.0	COG1536@1|root,COG1536@2|Bacteria,2IX0X@203682|Planctomycetes	203682|Planctomycetes	N	flagellar motor switch protein	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
CMS3_k127_2024785_29	754027.HMPREF9554_00215	2.942e-12	76.0	COG1317@1|root,COG1317@2|Bacteria,2J5KZ@203691|Spirochaetes	203691|Spirochaetes	N	Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
CMS3_k127_2024785_2	555079.Toce_1098	1.898e-131	440.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,42EPE@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_2024785_39	675814.VIC_004742	0.0009435	52.0	COG3144@1|root,COG3144@2|Bacteria,1N86W@1224|Proteobacteria,1SER0@1236|Gammaproteobacteria,1XXIJ@135623|Vibrionales	135623|Vibrionales	N	Flagellar hook-length control protein FliK	-	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
CMS3_k127_2024785_31	595460.RRSWK_05641	1.366e-11	74.0	COG1843@1|root,COG1843@2|Bacteria,2J0QK@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar hook capping protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD
CMS3_k127_2024785_8	1142394.PSMK_21660	8.543e-96	335.0	COG1749@1|root,COG1749@2|Bacteria,2IYJT@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
CMS3_k127_2024785_33	350688.Clos_1489	8.907e-10	63.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia,36MUF@31979|Clostridiaceae	186801|Clostridia	N	Flagellar FlbD family protein	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
CMS3_k127_2024785_12	344747.PM8797T_01399	4.196e-79	271.0	COG1291@1|root,COG1291@2|Bacteria,2IY3Y@203682|Planctomycetes	203682|Planctomycetes	N	COG1291 Flagellar motor component	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CMS3_k127_2024785_20	1142394.PSMK_17620	5.631e-44	171.0	COG1360@1|root,COG1360@2|Bacteria,2IZFU@203682|Planctomycetes	203682|Planctomycetes	N	COG1360 Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS3_k127_2024785_23	1142394.PSMK_23540	2.72e-30	129.0	COG1886@1|root,COG1886@2|Bacteria,2J00Z@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar motor switch type III secretory pathway	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
CMS3_k127_2024785_38	595460.RRSWK_05683	5.286e-07	60.0	COG3190@1|root,COG3190@2|Bacteria,2J1CS@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar biosynthesis protein, FliO	-	-	-	-	-	-	-	-	-	-	-	-	FliO
CMS3_k127_2024785_14	530564.Psta_4355	3.591e-63	226.0	COG1338@1|root,COG1338@2|Bacteria,2IXMG@203682|Planctomycetes	203682|Planctomycetes	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
CMS3_k127_2024785_28	1123288.SOV_1c11830	6.848e-16	82.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,4H54Q@909932|Negativicutes	909932|Negativicutes	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
CMS3_k127_2024785_24	1142394.PSMK_23500	2.416e-26	119.0	COG1684@1|root,COG1684@2|Bacteria,2J0P7@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar biosynthesis pathway component FliR	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
CMS3_k127_2024785_13	717605.Theco_2086	9.278e-78	273.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,26TRR@186822|Paenibacillaceae	91061|Bacilli	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
CMS3_k127_2024785_0	748449.Halha_0673	2.195e-188	610.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,3WABD@53433|Halanaerobiales	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
CMS3_k127_2024785_11	886293.Sinac_7410	1.652e-81	285.0	COG1419@1|root,COG1419@2|Bacteria,2IYTZ@203682|Planctomycetes	203682|Planctomycetes	N	GTP-binding signal recognition particle SRP54	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
CMS3_k127_2024785_15	1449126.JQKL01000001_gene1348	1.947e-62	226.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,26B2D@186813|unclassified Clostridiales	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
CMS3_k127_2024785_7	1142394.PSMK_22790	4.025e-97	323.0	COG1191@1|root,COG1191@2|Bacteria,2IX9S@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_2024785_9	886293.Sinac_3140	5.096e-94	317.0	COG0253@1|root,COG0253@2|Bacteria,2IYCH@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_2038022_1	661478.OP10G_0647	5.056e-45	174.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	yrhO	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	Regulator_TrmB,TrmB
CMS3_k127_2038022_0	1196323.ALKF01000191_gene5530	1.258e-67	250.0	COG1680@1|root,COG1680@2|Bacteria,1UT07@1239|Firmicutes,4HMEY@91061|Bacilli,26QSV@186822|Paenibacillaceae	91061|Bacilli	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS3_k127_2038816_1	530564.Psta_4673	9.509e-94	321.0	COG0404@1|root,COG0404@2|Bacteria,2IWRE@203682|Planctomycetes	203682|Planctomycetes	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS3_k127_2038816_4	42256.RradSPS_2740	7.378e-36	141.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_2038816_0	29581.BW37_01054	2.402e-120	405.0	COG0438@1|root,COG1541@1|root,COG0438@2|Bacteria,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VMX6@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Capsular polysaccharide biosynthesis protein CapK	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2038816_3	886293.Sinac_5459	2.099e-70	253.0	COG3146@1|root,COG3146@2|Bacteria,2J4VM@203682|Planctomycetes	203682|Planctomycetes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_2038816_2	305700.B447_02788	2.943e-78	277.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,2KUCI@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS3_k127_2038816_6	521674.Plim_4077	2.123e-26	119.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS3_k127_204875_5	105559.Nwat_0934	1.719e-25	108.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,1RP9Y@1236|Gammaproteobacteria,1WWGU@135613|Chromatiales	135613|Chromatiales	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	PGPGW,TerC
CMS3_k127_204875_0	391625.PPSIR1_40115	5.231e-247	780.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,42NBE@68525|delta/epsilon subdivisions,2WMG2@28221|Deltaproteobacteria,2YUJX@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_204875_4	882086.SacxiDRAFT_2388	1.759e-30	133.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria	201174|Actinobacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_204875_1	756272.Plabr_3423	8.354e-123	409.0	COG0621@1|root,COG0621@2|Bacteria,2IWTE@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
CMS3_k127_204875_3	344747.PM8797T_29897	1.041e-34	141.0	COG0558@1|root,COG0558@2|Bacteria,2IZQ1@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_204875_2	293826.Amet_4339	1.367e-53	200.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,36EFN@31979|Clostridiaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS3_k127_204875_6	1449346.JQMO01000003_gene3314	0.0002749	50.0	COG3595@1|root,COG3595@2|Bacteria,2GKT3@201174|Actinobacteria,2M0Y6@2063|Kitasatospora	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_2055929_1	1068980.ARVW01000001_gene43	6.377e-05	55.0	COG4447@1|root,COG4447@2|Bacteria,2ID0E@201174|Actinobacteria,4ECN1@85010|Pseudonocardiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2055929_0	983917.RGE_21670	4.023e-08	57.0	COG1305@1|root,COG4785@1|root,COG1305@2|Bacteria,COG4785@2|Bacteria,1R5Q7@1224|Proteobacteria,2VQ7C@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
CMS3_k127_2058370_2	562970.Btus_1869	7.301e-34	133.0	COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,2795U@186823|Alicyclobacillaceae	91061|Bacilli	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_2058370_3	1158338.JNLJ01000001_gene657	2.62e-22	104.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,2G45T@200783|Aquificae	200783|Aquificae	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_2058370_4	502025.Hoch_1730	2.11e-19	105.0	COG0402@1|root,COG2885@1|root,COG0402@2|Bacteria,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	MA20_26585	-	3.5.2.18	ko:K01305,ko:K15358	ko00760,ko01120,map00760,map01120	-	R07984	RC01933	ko00000,ko00001,ko01000,ko01002	-	-	-	Amidohydro_1,DUF4215
CMS3_k127_2058370_1	1379698.RBG1_1C00001G1377	1.068e-35	158.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
CMS3_k127_2058370_0	867903.ThesuDRAFT_01213	4.708e-45	166.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,25F3I@186801|Clostridia,3WCCI@538999|Clostridiales incertae sedis	186801|Clostridia	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS3_k127_2084872_1	530564.Psta_3898	2.976e-87	298.0	COG0508@1|root,COG0508@2|Bacteria,2IY0W@203682|Planctomycetes	203682|Planctomycetes	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_2084872_0	472759.Nhal_2902	1.234e-145	475.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS3_k127_2084872_2	477974.Daud_0086	6.479e-83	293.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,260U4@186807|Peptococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS3_k127_2084872_3	756272.Plabr_3982	7.157e-35	150.0	COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2084872_4	595460.RRSWK_03438	3.337e-10	74.0	COG2982@1|root,COG2982@2|Bacteria,2IYVI@203682|Planctomycetes	203682|Planctomycetes	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
CMS3_k127_2101821_2	1449355.JQNR01000004_gene1589	4.107e-26	127.0	COG3209@1|root,COG3271@1|root,COG3209@2|Bacteria,COG3271@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,Laminin_G_3,PT-HINT,RHS_repeat
CMS3_k127_2101821_3	1192034.CAP_1358	1.179e-10	76.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
CMS3_k127_2101821_1	224325.AF_2090-N	3.043e-30	141.0	COG3210@1|root,arCOG07534@2157|Archaea,2XVS6@28890|Euryarchaeota	28890|Euryarchaeota	M	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2101821_0	1463825.JNXC01000006_gene2153	1.954e-91	342.0	COG2304@1|root,COG4257@1|root,COG2304@2|Bacteria,COG4257@2|Bacteria,2IDJM@201174|Actinobacteria,4E2D1@85010|Pseudonocardiales	201174|Actinobacteria	V	Calx-beta domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HYR,VWA
CMS3_k127_2111704_1	521674.Plim_3642	8.263e-39	154.0	COG1943@1|root,COG1943@2|Bacteria,2J16A@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_2111704_0	1121957.ATVL01000007_gene1671	2.971e-45	175.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
CMS3_k127_2112936_5	502025.Hoch_5189	6.946e-64	223.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1NTJT@1224|Proteobacteria,42NK8@68525|delta/epsilon subdivisions,2WIM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
CMS3_k127_2112936_4	1123508.JH636439_gene1171	7.23e-67	243.0	COG1271@1|root,COG1271@2|Bacteria,2J2S2@203682|Planctomycetes	203682|Planctomycetes	C	oxidase subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2112936_0	204669.Acid345_4118	8.982e-237	761.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_2112936_6	401053.AciPR4_3842	2.281e-24	108.0	COG0251@1|root,COG0251@2|Bacteria,3Y57T@57723|Acidobacteria,2JJQ3@204432|Acidobacteriia	204432|Acidobacteriia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_2112936_8	1123322.KB904669_gene3661	1.596e-05	59.0	2B8T4@1|root,32236@2|Bacteria,2H6BU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2112936_2	1131812.JQMS01000001_gene2726	1.656e-154	531.0	COG1470@1|root,COG2304@1|root,COG3209@1|root,COG3391@1|root,COG1470@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia,2P0VG@237|Flavobacterium	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF5011,HYR,SprB
CMS3_k127_2112936_1	1122212.AULO01000010_gene109	1.249e-158	512.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1XIX5@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS3_k127_2112936_7	595460.RRSWK_07136	2.508e-22	98.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
CMS3_k127_2132370_0	1128421.JAGA01000002_gene632	2.382e-84	286.0	COG3508@1|root,COG3508@2|Bacteria,2NPWM@2323|unclassified Bacteria	2|Bacteria	Q	homogentisate 1,2-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CMS3_k127_2132370_1	643867.Ftrac_2029	1.754e-53	190.0	COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,47QIY@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
CMS3_k127_2132370_3	1123388.AQWU01000053_gene1547	1.116e-08	60.0	COG2329@1|root,COG2329@2|Bacteria,1WNCW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_2132370_2	1380391.JIAS01000019_gene1123	3.928e-29	121.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,2UCEY@28211|Alphaproteobacteria,2JXZD@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_2159828_0	215803.DB30_5880	0.0	1553.0	COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria,42Z37@68525|delta/epsilon subdivisions,2WUNE@28221|Deltaproteobacteria,2YZFR@29|Myxococcales	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_218329_1	344747.PM8797T_04795	7.625e-69	242.0	COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes	203682|Planctomycetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_218329_0	1382359.JIAL01000001_gene2624	9.08e-111	367.0	COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_218329_2	344747.PM8797T_04775	1.445e-66	245.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS3_k127_218329_4	1142394.PSMK_16440	1.436e-15	87.0	COG1612@1|root,COG1612@2|Bacteria,2IZCQ@203682|Planctomycetes	203682|Planctomycetes	O	protein required for cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS3_k127_218329_5	1192034.CAP_2034	2.977e-08	59.0	2DR0H@1|root,339NS@2|Bacteria,1R3N7@1224|Proteobacteria,42X1P@68525|delta/epsilon subdivisions,2X8S7@28221|Deltaproteobacteria,2Z3NK@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
CMS3_k127_218329_3	481448.Minf_1950	5.346e-50	184.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS3_k127_2186576_0	1267533.KB906733_gene3472	1.874e-112	383.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_2186576_2	314230.DSM3645_11631	3.325e-52	191.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_2186576_5	1137281.D778_01491	2.754e-06	60.0	COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,1I1PS@117743|Flavobacteriia	976|Bacteroidetes	MUW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CMS3_k127_2186576_3	324602.Caur_0300	5.248e-14	78.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2186576_4	765420.OSCT_0768	7.141e-14	85.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_2186576_1	1123278.KB893427_gene1235	6.929e-53	208.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2187972_2	997346.HMPREF9374_3445	4.047e-43	158.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
CMS3_k127_2187972_4	1121448.DGI_1524	6.223e-26	124.0	COG3291@1|root,COG3291@2|Bacteria,1PHGX@1224|Proteobacteria,437VV@68525|delta/epsilon subdivisions,2X1BB@28221|Deltaproteobacteria,2MEPR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
CMS3_k127_2187972_3	1123278.KB893427_gene1235	8.621e-30	137.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2187972_0	530564.Psta_2741	0.0	1213.0	COG0376@1|root,COG0376@2|Bacteria,2IY35@203682|Planctomycetes	203682|Planctomycetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS3_k127_2187972_1	469383.Cwoe_2725	8.295e-53	190.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,4CTCG@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_2193742_6	710111.FraQA3DRAFT_5494	2.835e-05	50.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
CMS3_k127_2193742_1	1394178.AWOO02000014_gene7787	1.886e-61	229.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4EG6I@85012|Streptosporangiales	201174|Actinobacteria	P	Bacterial Na+/H+ antiporter B (NhaB)	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
CMS3_k127_2193742_2	662479.C440_06892	6.784e-32	143.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_2193742_0	269799.Gmet_0070	3.019e-68	238.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,42QYA@68525|delta/epsilon subdivisions,2WNGC@28221|Deltaproteobacteria,43SEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	endonuclease III	nth	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
CMS3_k127_2193742_3	1142394.PSMK_28330	4.737e-23	110.0	COG1266@1|root,COG1266@2|Bacteria,2J06D@203682|Planctomycetes	203682|Planctomycetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2193742_4	935567.JAES01000028_gene2697	6.819e-20	96.0	29IJ4@1|root,313M6@2|Bacteria,1QGNE@1224|Proteobacteria,1TD6K@1236|Gammaproteobacteria,1XA86@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS3_k127_2207171_3	13037.EHJ66554	2.618e-05	56.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa,3CSKJ@33213|Bilateria,41YHD@6656|Arthropoda,3SIXR@50557|Insecta,442QD@7088|Lepidoptera	33208|Metazoa	M	Pectinacetylesterase	NOTUM	GO:0000902,GO:0000904,GO:0003002,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008045,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009952,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0012505,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019538,GO:0019637,GO:0021532,GO:0021915,GO:0022008,GO:0023051,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030163,GO:0030178,GO:0030182,GO:0031175,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0035220,GO:0035222,GO:0035295,GO:0035601,GO:0036211,GO:0040011,GO:0042157,GO:0042159,GO:0042221,GO:0042330,GO:0042578,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046486,GO:0046488,GO:0048070,GO:0048073,GO:0048076,GO:0048190,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0052689,GO:0060429,GO:0060828,GO:0061564,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0090090,GO:0097485,GO:0098732,GO:0120036,GO:0120039,GO:1901135,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1990697,GO:1990699	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_2207171_0	316274.Haur_2192	2.21e-37	162.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_2207171_1	1267533.KB906733_gene3215	2.494e-23	109.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_2229885_1	234267.Acid_4393	2.862e-94	335.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2229885_0	1232437.KL662020_gene704	7.156e-121	419.0	COG3591@1|root,COG5640@1|root,COG3591@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,PKD,PPC,Trypsin,Trypsin_2
CMS3_k127_2253163_1	1496688.ER33_11365	2.671e-14	77.0	COG1215@1|root,COG1215@2|Bacteria,1GHSH@1117|Cyanobacteria,22T8Q@167375|Cyanobium	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2253163_0	530564.Psta_2542	1.943e-73	265.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2258289_4	497964.CfE428DRAFT_0155	2.346e-94	313.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,46TEA@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116,polyprenyl_synt
CMS3_k127_2258289_11	497964.CfE428DRAFT_0155	2.635e-40	160.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,46TEA@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116,polyprenyl_synt
CMS3_k127_2258289_1	1123242.JH636435_gene1438	1.148e-172	550.0	COG0535@1|root,COG0535@2|Bacteria,2IX8N@203682|Planctomycetes	203682|Planctomycetes	S	enzyme of the MoaA nifB pqqE family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_2258289_7	497964.CfE428DRAFT_6362	1.955e-82	284.0	COG1146@1|root,COG1146@2|Bacteria,46TI2@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2258289_13	497964.CfE428DRAFT_6361	1.464e-36	143.0	2FICZ@1|root,34A57@2|Bacteria,46W7Z@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2258289_3	497964.CfE428DRAFT_4253	2.623e-116	388.0	COG0523@1|root,COG0523@2|Bacteria,46URF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SRP54-type protein, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
CMS3_k127_2258289_12	497964.CfE428DRAFT_6360	3.498e-39	150.0	COG0509@1|root,COG0509@2|Bacteria,46WCE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
CMS3_k127_2258289_8	324602.Caur_1179	9.724e-67	239.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi,374S3@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS3_k127_2258289_15	795359.TOPB45_0383	8.143e-36	143.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_2258289_10	497965.Cyan7822_3713	7.554e-51	189.0	COG1073@1|root,COG1073@2|Bacteria,1G60G@1117|Cyanobacteria,3KJNB@43988|Cyanothece	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_2258289_17	1163617.SCD_n02652	9.336e-18	88.0	COG1959@1|root,COG1959@2|Bacteria,1RE3F@1224|Proteobacteria,2VRIR@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_2258289_0	521674.Plim_0240	9.283e-265	844.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_2258289_5	670487.Ocepr_0388	3.824e-91	312.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2258289_2	1122222.AXWR01000010_gene85	4.413e-154	495.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_2258289_14	1170562.Cal6303_0766	5.658e-36	154.0	COG1451@1|root,COG1451@2|Bacteria,1G5F8@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
CMS3_k127_2258289_6	251221.35213066	8.007e-83	280.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS3_k127_2258289_9	377629.TERTU_3893	1.786e-53	191.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,2PNX1@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_2258289_16	1173026.Glo7428_3075	7.052e-35	140.0	COG1011@1|root,COG1011@2|Bacteria,1G4JI@1117|Cyanobacteria	1117|Cyanobacteria	S	dehalogenase, type II	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_2275422_0	234267.Acid_7680	9.12e-72	249.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_2275422_1	616991.JPOO01000003_gene29	2.398e-29	138.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_2275422_2	866546.EPY53444	5.339e-09	70.0	KOG3607@1|root,KOG3607@2759|Eukaryota,38B6W@33154|Opisthokonta,3NTZ6@4751|Fungi,3QJBF@4890|Ascomycota,3ME03@451866|Taphrinomycotina	4751|Fungi	O	Spore wall assembly peptidase Mde10	ADM-B	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005619,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009272,GO:0009277,GO:0009653,GO:0009987,GO:0010927,GO:0012505,GO:0016020,GO:0016043,GO:0016787,GO:0019538,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0030154,GO:0030312,GO:0030435,GO:0030437,GO:0030476,GO:0031160,GO:0031505,GO:0031984,GO:0032502,GO:0032505,GO:0032989,GO:0034293,GO:0042175,GO:0042244,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043934,GO:0043935,GO:0044085,GO:0044238,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045229,GO:0046872,GO:0046914,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0070011,GO:0070590,GO:0070591,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071852,GO:0071940,GO:0071944,GO:0098827,GO:0140096,GO:1901564,GO:1903046	-	-	-	-	-	-	-	-	-	-	Disintegrin,Reprolysin_5
CMS3_k127_2279552_10	84531.JMTZ01000001_gene2271	2.467e-14	86.0	COG3291@1|root,COG3420@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3	ko:K01337,ko:K01387,ko:K05994,ko:K08604,ko:K14645,ko:K20276	ko02024,ko05110,ko05111,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Inhibitor_I9,LVIVD,PKD,P_proprotein,Peptidase_M14,Peptidase_S8
CMS3_k127_2279552_13	1304885.AUEY01000006_gene742	8.953e-10	68.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,439X1@68525|delta/epsilon subdivisions,2WJBG@28221|Deltaproteobacteria,2MI1C@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Protein of unknown function (DUF3365)	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF3365,HAMP,MCPsignal
CMS3_k127_2279552_5	1521187.JPIM01000012_gene1661	7.826e-66	241.0	COG3291@1|root,COG3386@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,2GAQK@200795|Chloroflexi,3772E@32061|Chloroflexia	32061|Chloroflexia	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_2279552_2	1121468.AUBR01000028_gene1521	5.786e-75	262.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_2279552_7	323098.Nwi_3090	2.109e-38	152.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria,3K6HR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
CMS3_k127_2279552_6	1267535.KB906767_gene5001	2.4e-46	184.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS3_k127_2279552_8	1123371.ATXH01000007_gene572	1.636e-20	101.0	COG1525@1|root,COG2169@1|root,COG1525@2|Bacteria,COG2169@2|Bacteria,2GHU7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,SNase
CMS3_k127_2279552_12	1123242.JH636434_gene4348	6.526e-11	71.0	COG2165@1|root,COG2165@2|Bacteria,2IYB7@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_2279552_11	945543.VIBR0546_17468	3.534e-12	79.0	COG0510@1|root,COG0510@2|Bacteria,1MXSM@1224|Proteobacteria,1TIZ0@1236|Gammaproteobacteria,1Y028@135623|Vibrionales	135623|Vibrionales	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_2279552_9	42256.RradSPS_2702	2.021e-14	87.0	COG0510@1|root,COG0510@2|Bacteria,2I4BX@201174|Actinobacteria	201174|Actinobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_2279552_0	864051.BurJ1DRAFT_3970	2.361e-132	444.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KKC9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_2279552_3	397278.JOJN01000001_gene2784	5.145e-74	267.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DSH1@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2279552_1	743299.Acife_1001	5.084e-81	286.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,2NDM4@225057|Acidithiobacillales	225057|Acidithiobacillales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS3_k127_2279552_4	1121448.DGI_2233	1.688e-70	256.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,42MDW@68525|delta/epsilon subdivisions,2WKQK@28221|Deltaproteobacteria,2M92X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyltransferase 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
CMS3_k127_2297212_2	671143.DAMO_1998	0.0005841	49.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367,DUF5122
CMS3_k127_2297212_0	1185876.BN8_02868	1.591e-52	192.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2297212_1	324602.Caur_0299	6.764e-45	179.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_2297458_2	1306174.JODP01000001_gene4897	1.854e-05	55.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria	201174|Actinobacteria	K	domain protein	rpfB	GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
CMS3_k127_2297458_0	439235.Dalk_1394	7.183e-131	435.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42SZ7@68525|delta/epsilon subdivisions,2WPA5@28221|Deltaproteobacteria,2MKE2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_2297458_1	1121430.JMLG01000026_gene2	7.133e-42	162.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	QU41_16170	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S15
CMS3_k127_2334994_0	1131553.JIBI01000046_gene1604	1.693e-93	324.0	COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria,2WGXZ@28216|Betaproteobacteria,3722U@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS3_k127_2334994_1	1499967.BAYZ01000074_gene2101	7.214e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_2344695_3	566466.NOR53_3558	1.808e-15	78.0	2C852@1|root,32YB2@2|Bacteria,1RH28@1224|Proteobacteria,1TH5C@1236|Gammaproteobacteria,1J8I3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS3_k127_2344695_0	565045.NOR51B_948	1.068e-67	240.0	COG3637@1|root,COG3637@2|Bacteria,1R0YP@1224|Proteobacteria,1T4RY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2344695_2	319224.Sputcn32_0996	1.278e-25	115.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1SF8S@1236|Gammaproteobacteria,2QBM3@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS3_k127_2344695_1	991.IW20_22815	4.541e-46	178.0	COG5164@1|root,COG5164@2|Bacteria,4NFN0@976|Bacteroidetes,1IMWB@117743|Flavobacteriia,2NVM5@237|Flavobacterium	976|Bacteroidetes	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2355776_0	502025.Hoch_2677	1.383e-07	62.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_2355776_1	5786.XP_003287836.1	0.0007277	53.0	2D42B@1|root,2STKH@2759|Eukaryota,3XEFZ@554915|Amoebozoa	554915|Amoebozoa	S	PA14 domain	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Dicty_CTDC,PA14
CMS3_k127_2360269_1	1121289.JHVL01000038_gene2990	9.091e-161	528.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,36DEB@31979|Clostridiaceae	186801|Clostridia	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
CMS3_k127_2360269_5	340177.Cag_1760	2.268e-31	132.0	COG2227@1|root,COG2227@2|Bacteria,1FFQD@1090|Chlorobi	1090|Chlorobi	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
CMS3_k127_2360269_0	234267.Acid_5940	5.843e-206	671.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2360269_2	1379698.RBG1_1C00001G0607	4.605e-134	481.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
CMS3_k127_2360269_4	1082933.MEA186_06086	1.048e-63	252.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1R20U@1224|Proteobacteria,2U3F2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6
CMS3_k127_2360269_3	1434929.X946_1416	4.862e-76	293.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2VZN8@28216|Betaproteobacteria,1KGFG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17
CMS3_k127_2360269_6	234267.Acid_3938	7.081e-26	108.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_2360843_2	479431.Namu_4273	1.047e-27	115.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2360843_1	247490.KSU1_C0446	4.369e-50	187.0	COG0500@1|root,COG2226@2|Bacteria,2J1BD@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_2360843_3	1230457.C476_02932	1.012e-21	99.0	COG0662@1|root,arCOG03003@2157|Archaea,2XZQ5@28890|Euryarchaeota	28890|Euryarchaeota	G	Mannose-6-phosphate isomerase	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Cupin_2
CMS3_k127_2360843_0	1128421.JAGA01000002_gene1741	1.069e-61	223.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_2360843_4	1052684.PPM_4557	1.945e-16	94.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_2407962_1	566461.SSFG_05974	3.484e-28	114.0	2DMHR@1|root,32RMI@2|Bacteria,2HC0U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2407962_2	1122991.BAIZ01000113_gene3011	1.116e-07	53.0	2E4EA@1|root,32Z9I@2|Bacteria,4NTWC@976|Bacteroidetes,2FU6R@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2407962_0	314230.DSM3645_20627	2.142e-105	354.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2409504_3	661478.OP10G_0316	9.353e-94	316.0	2BZ4W@1|root,2Z7PQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2409504_8	82654.Pse7367_2411	0.0006972	44.0	COG0606@1|root,COG0606@2|Bacteria,1G0K1@1117|Cyanobacteria,1H6YU@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Magnesium chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS3_k127_2409504_0	344747.PM8797T_11069	8.49e-182	584.0	COG0606@1|root,COG0606@2|Bacteria,2IWTT@203682|Planctomycetes	203682|Planctomycetes	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS3_k127_2409504_5	1380346.JNIH01000048_gene6679	1.688e-20	103.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS3_k127_2409504_4	1379270.AUXF01000001_gene1941	1.41e-61	241.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZUHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_2409504_7	886293.Sinac_6754	2.11e-09	66.0	COG1595@1|root,COG1595@2|Bacteria,2J02A@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2409504_2	1210884.HG799464_gene11020	5.188e-129	429.0	COG1541@1|root,COG1541@2|Bacteria,2IXI4@203682|Planctomycetes	203682|Planctomycetes	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS3_k127_2409504_1	344747.PM8797T_21603	4.831e-167	551.0	COG1520@1|root,COG1520@2|Bacteria,2IX37@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2409504_6	1123242.JH636436_gene34	8.814e-11	69.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_2414792_2	1121448.DGI_2643	1.409e-11	64.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,43EAS@68525|delta/epsilon subdivisions,2X7TI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_2414792_0	314230.DSM3645_28142	3.559e-114	386.0	COG3316@1|root,COG3316@2|Bacteria,2J4XX@203682|Planctomycetes	203682|Planctomycetes	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
CMS3_k127_2414792_1	1254432.SCE1572_36420	7.14e-30	128.0	COG3436@1|root,COG3436@2|Bacteria,1RHDW@1224|Proteobacteria,43BFC@68525|delta/epsilon subdivisions,2X6TQ@28221|Deltaproteobacteria,2Z3CQ@29|Myxococcales	28221|Deltaproteobacteria	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
CMS3_k127_2418160_1	337191.KTR9_4057	4.942e-08	59.0	COG0662@1|root,COG3620@1|root,COG0662@2|Bacteria,COG3620@2|Bacteria,2I35Q@201174|Actinobacteria,4GA96@85026|Gordoniaceae	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS3_k127_2425430_2	886293.Sinac_0002	4.18e-64	231.0	COG0593@1|root,COG0593@2|Bacteria,2IWXU@203682|Planctomycetes	203682|Planctomycetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS3_k127_2425430_5	886293.Sinac_7563	8.675e-31	136.0	COG0454@1|root,COG0456@2|Bacteria,2J0RJ@203682|Planctomycetes	203682|Planctomycetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2425430_7	1121448.DGI_0101	7.904e-14	79.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,42Z10@68525|delta/epsilon subdivisions,2WU0N@28221|Deltaproteobacteria,2M9PY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
CMS3_k127_2425430_6	335543.Sfum_2311	2.943e-23	104.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42VTR@68525|delta/epsilon subdivisions,2X5PP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS3_k127_2425430_3	530564.Psta_2541	5.13e-64	236.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CMS3_k127_2425430_0	1120999.JONM01000002_gene649	3.165e-135	446.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2VHRA@28216|Betaproteobacteria,2KPCG@206351|Neisseriales	206351|Neisseriales	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
CMS3_k127_2425430_1	439292.Bsel_0911	1.764e-73	268.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,26Q7M@186821|Sporolactobacillaceae	91061|Bacilli	U	Branched-chain amino acid transport system / permease component	rbsC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CMS3_k127_2425430_4	768671.ThimaDRAFT_3893	2.344e-46	172.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS3_k127_2426067_7	316067.Geob_3070	6.946e-14	85.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,43UK6@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_2426067_3	521674.Plim_3639	1.085e-45	187.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
CMS3_k127_2426067_9	1303518.CCALI_00193	0.0002259	53.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS3_k127_2426067_10	85643.Tmz1t_2532	0.000629	51.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR7N@28216|Betaproteobacteria,2KWEI@206389|Rhodocyclales	206389|Rhodocyclales	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_2426067_5	933262.AXAM01000042_gene1813	8.829e-25	110.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2MKEC@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_2426067_0	344747.PM8797T_14319	5.194e-93	320.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_2426067_1	1123371.ATXH01000002_gene336	1.344e-48	182.0	COG0283@1|root,COG0283@2|Bacteria,2GHQ2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS3_k127_2426067_2	1142394.PSMK_27400	3.596e-46	175.0	COG0745@1|root,COG0745@2|Bacteria,2IY82@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
CMS3_k127_2426067_6	8010.XP_010902979.1	2.355e-14	78.0	2CDB0@1|root,2S5FA@2759|Eukaryota,38DQQ@33154|Opisthokonta,3BH0H@33208|Metazoa,3CSSQ@33213|Bilateria,485TW@7711|Chordata,48UXT@7742|Vertebrata,4A37X@7898|Actinopterygii	33208|Metazoa	E	Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine)	DIO3	GO:0001654,GO:0001754,GO:0003407,GO:0003674,GO:0003824,GO:0004800,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0006915,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009653,GO:0009887,GO:0009987,GO:0010721,GO:0010817,GO:0012501,GO:0016020,GO:0016491,GO:0018958,GO:0019336,GO:0019439,GO:0022008,GO:0022603,GO:0030154,GO:0030182,GO:0032501,GO:0032502,GO:0033798,GO:0040008,GO:0040014,GO:0040018,GO:0042219,GO:0042403,GO:0042404,GO:0042445,GO:0042447,GO:0042461,GO:0042462,GO:0042478,GO:0042480,GO:0042670,GO:0043010,GO:0044237,GO:0044248,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045927,GO:0046530,GO:0046532,GO:0046533,GO:0046549,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048592,GO:0048593,GO:0048638,GO:0048639,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051094,GO:0051239,GO:0051240,GO:0051241,GO:0051402,GO:0051960,GO:0051961,GO:0055114,GO:0060041,GO:0060042,GO:0060219,GO:0060284,GO:0065007,GO:0065008,GO:0070997,GO:0071704,GO:0071944,GO:0090596,GO:0097474,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901615,GO:1901616,GO:1990009,GO:2000026,GO:2000027	1.21.99.3,1.21.99.4	ko:K01562,ko:K07754	ko04919,map04919	-	-	-	ko00000,ko00001,ko01000	-	-	-	T4_deiodinase
CMS3_k127_2426067_4	502025.Hoch_0626	5.442e-26	121.0	COG3055@1|root,COG3055@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2487799_6	314230.DSM3645_18936	1.117e-58	212.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_2487799_8	314230.DSM3645_18931	1.286e-15	81.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
CMS3_k127_2487799_4	1210884.HG799464_gene10528	2.61e-125	414.0	COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes	203682|Planctomycetes	C	COG0644 Dehydrogenases (flavoproteins)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CMS3_k127_2487799_7	530564.Psta_0176	6.604e-30	129.0	COG3161@1|root,COG3161@2|Bacteria,2IZQI@203682|Planctomycetes	203682|Planctomycetes	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2487799_2	1123508.JH636444_gene5485	1.501e-158	513.0	COG0635@1|root,COG0635@2|Bacteria,2IY84@203682|Planctomycetes	203682|Planctomycetes	H	COG0635 Coproporphyrinogen III oxidase and related Fe-S	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_2487799_5	240016.ABIZ01000001_gene1452	2.84e-119	399.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia,2IUNH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS3_k127_2487799_1	1123508.JH636440_gene2677	1.4e-177	571.0	COG1012@1|root,COG1012@2|Bacteria,2IXUV@203682|Planctomycetes	203682|Planctomycetes	C	COG1012 NAD-dependent aldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS3_k127_2487799_3	521674.Plim_3329	2.633e-146	472.0	COG1541@1|root,COG1541@2|Bacteria,2IWUR@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2487799_0	344747.PM8797T_21598	9.774e-185	586.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_2490744_5	266117.Rxyl_1186	1.528e-12	78.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_2490744_3	1123508.JH636442_gene3868	5.306e-42	167.0	COG1959@1|root,COG1959@2|Bacteria,2IZQA@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_2490744_0	1237149.C900_01467	0.0	1165.0	COG3256@1|root,COG3256@2|Bacteria,4NG9H@976|Bacteroidetes,47K63@768503|Cytophagia	976|Bacteroidetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
CMS3_k127_2490744_1	1303518.CCALI_00076	4.107e-72	250.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ytfE	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0030091,GO:0031163,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0071840,GO:1901564	-	ko:K07322	-	-	-	-	ko00000	-	-	iECED1_1282.ECED1_5068,iECH74115_1262.ECH74115_5726,iECSP_1301.ECSP_5311,iECs_1301.ECs5187,iG2583_1286.G2583_5039,iZ_1308.Z5820	Hemerythrin,ScdA_N
CMS3_k127_2490744_2	1232410.KI421426_gene1437	3.393e-55	200.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria,43UQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2490744_4	1041146.ATZB01000001_gene4861	6.869e-16	90.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,2VF65@28211|Alphaproteobacteria,4BBA2@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase for insertion sequence element	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS3_k127_2507558_0	251221.35213042	4.034e-104	350.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_2507558_4	880071.Fleli_2403	4.627e-24	106.0	arCOG10603@1|root,32SV6@2|Bacteria,4NFE9@976|Bacteroidetes,47RY3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2507558_3	880071.Fleli_2403	1.474e-26	113.0	arCOG10603@1|root,32SV6@2|Bacteria,4NFE9@976|Bacteroidetes,47RY3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2507558_2	344747.PM8797T_17569	6.567e-49	194.0	COG0477@1|root,COG2814@2|Bacteria,2J074@203682|Planctomycetes	203682|Planctomycetes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2507558_1	1280949.HAD_15002	2.746e-101	344.0	COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,2TUDY@28211|Alphaproteobacteria,43X23@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
CMS3_k127_2528415_0	653733.Selin_0842	7.445e-194	621.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	sulP	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	iSbBS512_1146.SbBS512_E1370	STAS,Sulfate_transp
CMS3_k127_2528415_2	1216932.CM240_0090	0.0003493	54.0	COG4412@1|root,COG4412@2|Bacteria,1TTSA@1239|Firmicutes,25BHE@186801|Clostridia,36WJX@31979|Clostridiaceae	186801|Clostridia	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
CMS3_k127_2528415_1	1122176.KB903587_gene4412	1.079e-32	140.0	COG1044@1|root,COG1044@2|Bacteria	2|Bacteria	M	lipid A biosynthetic process	ydcK	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Hexapep
CMS3_k127_2529713_3	616991.JPOO01000003_gene903	1.618e-19	90.0	2EBGV@1|root,335HF@2|Bacteria,4NV5E@976|Bacteroidetes,1I6Q2@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2529713_6	702113.PP1Y_AT36129	0.0001562	45.0	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria,2UJNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2529713_4	498761.HM1_3125	3.779e-10	60.0	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,24VWA@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2529713_5	568703.LGG_02503	1.192e-05	52.0	2DSV3@1|root,33HII@2|Bacteria,1VQ64@1239|Firmicutes,4IGTW@91061|Bacilli,3F8RY@33958|Lactobacillaceae	91061|Bacilli	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2529713_2	326427.Cagg_2551	4.43e-90	305.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,374VN@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
CMS3_k127_2529713_0	1267533.KB906733_gene3472	4.869e-151	511.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_2529713_1	240016.ABIZ01000001_gene875	5.9e-131	431.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2530478_0	1122134.KB893650_gene1358	9.348e-149	487.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CMS3_k127_2530478_1	706587.Desti_5519	9.016e-28	113.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MQ90@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
CMS3_k127_2531786_5	1142394.PSMK_13510	3.172e-26	119.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2IYEP@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
CMS3_k127_2531786_1	1480694.DC28_00035	4.396e-77	265.0	COG0217@1|root,COG0217@2|Bacteria,2J634@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS3_k127_2531786_0	926551.KB900709_gene1126	1.24e-161	520.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1HY7D@117743|Flavobacteriia,1EQRW@1016|Capnocytophaga	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_2531786_4	429009.Adeg_1397	3.417e-40	159.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,42FIN@68295|Thermoanaerobacterales	186801|Clostridia	J	Ribosomal RNA methyltransferase RrmJ FtsJ	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS3_k127_2531786_7	1415775.U729_56	2.853e-11	67.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,36KIE@31979|Clostridiaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS3_k127_2531786_6	349741.Amuc_1443	4.422e-16	92.0	COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia,2ITH6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS3_k127_2531786_3	1142394.PSMK_24190	5.738e-45	170.0	COG0242@1|root,COG0242@2|Bacteria,2IZ6R@203682|Planctomycetes	203682|Planctomycetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS3_k127_2531786_2	330214.NIDE0395	1.355e-58	216.0	COG0223@1|root,COG0223@2|Bacteria,3J0GW@40117|Nitrospirae	40117|Nitrospirae	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS3_k127_2557615_10	215803.DB30_8375	3.112e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,1Q7GW@1224|Proteobacteria,438R6@68525|delta/epsilon subdivisions,2X96H@28221|Deltaproteobacteria,2YXJM@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2557615_0	404380.Gbem_1628	8.263e-140	467.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42PUB@68525|delta/epsilon subdivisions,2WMH5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_2557615_2	795797.C497_10933	1.164e-50	203.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2557615_3	931277.C448_14525	5.906e-47	191.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2557615_7	1122137.AQXF01000001_gene3108	2.407e-20	102.0	COG2220@1|root,COG2220@2|Bacteria,1RKSI@1224|Proteobacteria,2UNK6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_2557615_4	756272.Plabr_1361	2.894e-42	166.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CMS3_k127_2557615_1	641491.DND132_3430	6.804e-120	399.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2WJ6Y@28221|Deltaproteobacteria,2M8I4@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
CMS3_k127_2557615_9	760192.Halhy_4996	8.885e-07	59.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS3_k127_2557615_6	1192034.CAP_1358	1.164e-25	124.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
CMS3_k127_2557615_5	1223410.KN050846_gene39	1.863e-29	138.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,4NQIZ@976|Bacteroidetes,1IJKK@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2557615_12	159749.K0T0B9	0.000628	53.0	COG1404@1|root,KOG1153@2759|Eukaryota,2XCPP@2836|Bacillariophyta	2759|Eukaryota	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	EGF_CA,Peptidase_S8
CMS3_k127_2557615_8	1120965.AUBV01000015_gene1141	2.347e-08	68.0	COG3291@1|root,COG4935@1|root,COG5184@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,47SFQ@768503|Cytophagia	976|Bacteroidetes	O	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-binding_MopE,DUF11,HYR,Laminin_G_3,PKD,SprB
CMS3_k127_2561092_0	1382359.JIAL01000001_gene1317	2.831e-176	563.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
CMS3_k127_2561092_1	595460.RRSWK_00671	1.809e-61	219.0	COG1244@1|root,COG1244@2|Bacteria,2IX1W@203682|Planctomycetes	203682|Planctomycetes	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_2566765_1	1382306.JNIM01000001_gene2616	1.665e-45	167.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_2566765_2	1121422.AUMW01000025_gene349	7.268e-38	146.0	COG1278@1|root,COG1278@2|Bacteria,1VWWT@1239|Firmicutes,251UG@186801|Clostridia,265GV@186807|Peptococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
CMS3_k127_2566765_0	439235.Dalk_4360	3.037e-80	277.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2MHYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS3_k127_2585412_5	1121920.AUAU01000009_gene1864	5.975e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,3Y5YE@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2585412_0	595460.RRSWK_04692	1.364e-119	394.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_2585412_4	344747.PM8797T_08364	7.635e-12	68.0	2DRVG@1|root,33D8Q@2|Bacteria,2J19Z@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2585412_2	1185876.BN8_00865	6.747e-93	323.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,47X4G@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
CMS3_k127_2585412_1	926550.CLDAP_04870	6.714e-93	325.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_2585412_3	1197477.IA57_00005	1.011e-51	206.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B,VWA,VWA_2
CMS3_k127_2616333_1	530564.Psta_3365	1.078e-126	421.0	COG0042@1|root,COG0042@2|Bacteria,2IYH0@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
CMS3_k127_2616333_3	1142394.PSMK_10290	2.652e-85	300.0	COG1508@1|root,COG1508@2|Bacteria,2IXGU@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS3_k127_2616333_5	314230.DSM3645_28657	1.223e-59	212.0	COG0353@1|root,COG0353@2|Bacteria,2IXK5@203682|Planctomycetes	203682|Planctomycetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS3_k127_2616333_8	56780.SYN_00162	3.27e-22	99.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,2MQNE@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS3_k127_2616333_2	1142394.PSMK_05840	1.467e-98	341.0	COG2812@1|root,COG2812@2|Bacteria,2IX1M@203682|Planctomycetes	203682|Planctomycetes	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS3_k127_2616333_4	518766.Rmar_2335	9.382e-64	226.0	COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes,1FJ9V@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS3_k127_2616333_6	443144.GM21_3051	2.863e-52	191.0	COG1280@1|root,COG1280@2|Bacteria,1RF18@1224|Proteobacteria,42RK6@68525|delta/epsilon subdivisions,2WNHB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS3_k127_2616333_0	583355.Caka_0064	4.98e-276	858.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	napA	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0008150,GO:0008152,GO:0008940,GO:0009061,GO:0009325,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016661,GO:0030151,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:1902494	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_2447,iECABU_c1320.ECABU_c25400,iECO103_1326.ECO103_2681,iECSE_1348.ECSE_2474,iECSF_1327.ECSF_2087,iECUMN_1333.ECUMN_2541,iEcHS_1320.EcHS_A2344,iEcolC_1368.EcolC_1444,iPC815.YPO3038,iSSON_1240.SSON_2264,ic_1306.c2745	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
CMS3_k127_2631634_1	1200792.AKYF01000010_gene2389	1.079e-107	358.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,26QMU@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2631634_2	1142394.PSMK_28250	1.976e-100	359.0	COG1033@1|root,COG1033@2|Bacteria,2J56E@203682|Planctomycetes	203682|Planctomycetes	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_2631634_5	316274.Haur_3958	2.468e-60	227.0	COG0236@1|root,COG0318@1|root,COG0236@2|Bacteria,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2631634_3	1142394.PSMK_30160	6.554e-100	341.0	COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes	203682|Planctomycetes	C	COG0644 Dehydrogenases (flavoproteins)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CMS3_k127_2631634_8	396595.TK90_1999	5.355e-30	135.0	COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,1S4VD@1236|Gammaproteobacteria,1X2I0@135613|Chromatiales	135613|Chromatiales	J	pteridine-dependent deoxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2631634_0	1142394.PSMK_30840	3.074e-134	456.0	COG0304@1|root,COG0304@2|Bacteria,2J1Z9@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_2631634_7	1142394.PSMK_30850	8.074e-46	179.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.241,2.3.1.265	ko:K02517,ko:K20543,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	1.B.55.3	-	-	Lip_A_acyltrans
CMS3_k127_2631634_9	1142394.PSMK_30870	3.528e-26	115.0	COG0236@1|root,COG0764@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria	2|Bacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	fabZ	-	3.5.1.108,4.2.1.59	ko:K02078,ko:K02372,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212	M00060,M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,PP-binding
CMS3_k127_2631634_12	1142394.PSMK_30870	4.898e-09	63.0	COG0236@1|root,COG0764@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria	2|Bacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	fabZ	-	3.5.1.108,4.2.1.59	ko:K02078,ko:K02372,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212	M00060,M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,PP-binding
CMS3_k127_2631634_4	391625.PPSIR1_16620	6.958e-73	261.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CMS3_k127_2631634_6	555779.Dthio_PD0796	8.947e-49	191.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,1QVEM@1224|Proteobacteria,42NYG@68525|delta/epsilon subdivisions,2WIXP@28221|Deltaproteobacteria,2M9VX@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF2062,Glycos_transf_2
CMS3_k127_2644325_1	335543.Sfum_2647	1.043e-09	59.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2MR64@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_2644325_0	693661.Arcve_1601	1.119e-44	175.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS3_k127_2678154_0	627192.SLG_24600	4.291e-161	524.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2UKU2@28211|Alphaproteobacteria,2K9NF@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_2698843_0	1469245.JFBG01000056_gene2465	1.095e-72	253.0	COG3324@1|root,COG3324@2|Bacteria,1QM05@1224|Proteobacteria,1SEG3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_2698843_4	768706.Desor_4658	2.264e-12	79.0	COG2318@1|root,COG2318@2|Bacteria,1V8MI@1239|Firmicutes	1239|Firmicutes	S	PFAM DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CMS3_k127_2698843_3	518766.Rmar_2569	7.342e-17	91.0	COG1266@1|root,COG1266@2|Bacteria,4PEJM@976|Bacteroidetes,1FJ86@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2698843_2	1267533.KB906735_gene4583	2.293e-45	167.0	COG2041@1|root,COG2041@2|Bacteria,3Y3AI@57723|Acidobacteria,2JHW2@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS3_k127_2698843_1	1172179.AUKV01000010_gene4193	2.5e-67	240.0	COG1228@1|root,COG1228@2|Bacteria,2I98N@201174|Actinobacteria	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_2704081_2	1528106.JRJE01000003_gene915	7.271e-55	198.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,2TW88@28211|Alphaproteobacteria,2JUM3@204441|Rhodospirillales	204441|Rhodospirillales	E	Spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2704081_3	886293.Sinac_0549	2.21e-31	129.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_2704081_1	330214.NIDE3593	3.511e-72	278.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
CMS3_k127_2704081_0	868595.Desca_1686	3.635e-159	509.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,2602X@186807|Peptococcaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2705608_4	316278.SynRCC307_1811	1.722e-06	59.0	COG0568@1|root,COG0568@2|Bacteria,1GBQG@1117|Cyanobacteria,1GYSR@1129|Synechococcus	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_2705608_3	314230.DSM3645_24295	2.051e-07	57.0	COG1555@1|root,COG1555@2|Bacteria,2J19U@203682|Planctomycetes	203682|Planctomycetes	L	COG1555 DNA uptake protein and related DNA-binding	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
CMS3_k127_2705608_1	1142394.PSMK_21970	4.871e-108	368.0	COG3693@1|root,COG3693@2|Bacteria,2IXI6@203682|Planctomycetes	203682|Planctomycetes	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
CMS3_k127_2705608_2	59374.Fisuc_0211	2.768e-105	351.0	COG0152@1|root,COG0152@2|Bacteria	2|Bacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945,ko:K03566	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SAICAR_synt
CMS3_k127_2705608_0	926550.CLDAP_03770	1.049e-109	366.0	COG0176@1|root,COG0176@2|Bacteria,2GA93@200795|Chloroflexi	200795|Chloroflexi	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS3_k127_2705608_5	1095769.CAHF01000014_gene3066	0.0002943	53.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,473SR@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS3_k127_2726729_0	944481.JAFP01000001_gene376	6.381e-142	464.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2M6PK@213113|Desulfurellales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS3_k127_2726729_2	411489.CLOL250_00100	1.375e-22	106.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,36FYW@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_2726729_1	857087.Metme_2233	1.657e-61	232.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XGE2@135618|Methylococcales	135618|Methylococcales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2726729_4	644282.Deba_0161	1.97e-16	86.0	COG1708@1|root,COG1708@2|Bacteria,1NMP8@1224|Proteobacteria,42Y4J@68525|delta/epsilon subdivisions,2WSMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2733121_0	68219.JNXI01000054_gene182	4.47e-130	457.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_2733121_1	203124.Tery_0599	9.228e-23	116.0	COG1572@1|root,COG3391@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
CMS3_k127_2751804_10	575540.Isop_0431	5.292e-19	96.0	2EUZ2@1|root,33NE9@2|Bacteria,2J1BN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2751804_1	204669.Acid345_1684	1.026e-149	494.0	COG0457@1|root,COG0457@2|Bacteria,3Y2M9@57723|Acidobacteria,2JMD8@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_2751804_0	518766.Rmar_1754	5.041e-155	526.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1754|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2751804_7	530564.Psta_0797	1.009e-53	205.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2751804_4	344747.PM8797T_16665	5.36e-58	223.0	COG1520@1|root,COG1520@2|Bacteria,2J2HQ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2751804_6	497964.CfE428DRAFT_0769	4.472e-56	213.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2751804_5	595460.RRSWK_06052	8.545e-57	214.0	COG1520@1|root,COG1520@2|Bacteria,2IWWY@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_2751804_3	344747.PM8797T_21408	2.929e-95	325.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_2751804_9	344747.PM8797T_12743	4.281e-25	111.0	2EK8J@1|root,33DYX@2|Bacteria,2J1AU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2751804_8	1123508.JH636441_gene3737	1.224e-32	131.0	COG0824@1|root,COG0824@2|Bacteria,2J02N@203682|Planctomycetes	203682|Planctomycetes	S	Thioesterase superfamily	-	-	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT
CMS3_k127_2751804_2	344747.PM8797T_12763	1.613e-148	482.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_2753826_0	1535422.ND16A_2156	3.562e-74	281.0	COG1800@1|root,COG5184@1|root,COG1800@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_5,CHU_C,CW_binding_2,Cadherin-like,CarboxypepD_reg,Laminin_G_3,SLH
CMS3_k127_2753826_1	1317122.ATO12_02615	6.773e-26	119.0	COG0823@1|root,COG0823@2|Bacteria,4NYXJ@976|Bacteroidetes,1IHT2@117743|Flavobacteriia,2YJBR@290174|Aquimarina	976|Bacteroidetes	U	Domain of unknown function (DUF5050)	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_2753826_2	1254432.SCE1572_22375	5.082e-13	83.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_275535_21	391623.TERMP_01927	4.66e-24	105.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota,243PQ@183968|Thermococci	183968|Thermococci	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_275535_9	1142394.PSMK_05860	9.409e-73	261.0	COG1043@1|root,COG1043@2|Bacteria,2IYJJ@203682|Planctomycetes	203682|Planctomycetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS3_k127_275535_1	1142394.PSMK_05870	1.214e-131	436.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2IZ4S@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108,4.2.1.59	ko:K02535,ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CMS3_k127_275535_27	1142394.PSMK_07160	1.647e-06	58.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS3_k127_275535_14	903818.KI912268_gene1998	7.928e-53	203.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	dadA	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_275535_26	44689.DDB0216219	8.362e-08	67.0	2CVSQ@1|root,2RSRD@2759|Eukaryota,3XFDQ@554915|Amoebozoa	554915|Amoebozoa	O	extracellular structure organization	-	GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0016043,GO:0030198,GO:0030587,GO:0031012,GO:0031154,GO:0032502,GO:0042221,GO:0043062,GO:0044421,GO:0048856,GO:0050896,GO:0051703,GO:0051704,GO:0071840,GO:0080184,GO:0090702,GO:0099120,GO:1901700,GO:1902168,GO:1905395	-	-	-	-	-	-	-	-	-	-	Dicty_CTDC
CMS3_k127_275535_5	530564.Psta_0830	1.996e-101	340.0	COG2374@1|root,COG2374@2|Bacteria,2J1PX@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_275535_0	1123368.AUIS01000011_gene1122	7.031e-314	970.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,2NC7S@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS3_k127_275535_20	643562.Daes_1195	5.947e-25	115.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WQQK@28221|Deltaproteobacteria,2MAX9@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS3_k127_275535_28	1142394.PSMK_05820	3.301e-06	55.0	COG1344@1|root,COG1344@2|Bacteria,2IX6G@203682|Planctomycetes	203682|Planctomycetes	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
CMS3_k127_275535_10	756272.Plabr_1703	6.006e-70	258.0	COG0772@1|root,COG0772@2|Bacteria,2IZRI@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS3_k127_275535_16	1479235.KK366039_gene870	9.566e-49	199.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,1XHM0@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS3_k127_275535_24	1142394.PSMK_10470	1.597e-11	76.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2
CMS3_k127_275535_11	247490.KSU1_C0172	3.191e-69	257.0	COG0815@1|root,COG0815@2|Bacteria,2IWUW@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_275535_7	1210884.HG799462_gene8732	5.218e-76	271.0	COG0303@1|root,COG0303@2|Bacteria,2IXJ1@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor synthesis domain protein	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_275535_23	1178482.BJB45_15310	4.144e-13	71.0	COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,1XM0J@135619|Oceanospirillales	135619|Oceanospirillales	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_275535_4	1123508.JH636450_gene7178	2.865e-117	383.0	COG2022@1|root,COG2104@1|root,COG2022@2|Bacteria,COG2104@2|Bacteria,2IY2Y@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
CMS3_k127_275535_12	1142394.PSMK_31090	8.291e-61	221.0	COG2159@1|root,COG2159@2|Bacteria,2IXTD@203682|Planctomycetes	203682|Planctomycetes	S	TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_275535_19	44689.DDB0216219	1.864e-32	144.0	2CVSQ@1|root,2RSRD@2759|Eukaryota,3XFDQ@554915|Amoebozoa	554915|Amoebozoa	O	extracellular structure organization	-	GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0016043,GO:0030198,GO:0030587,GO:0031012,GO:0031154,GO:0032502,GO:0042221,GO:0043062,GO:0044421,GO:0048856,GO:0050896,GO:0051703,GO:0051704,GO:0071840,GO:0080184,GO:0090702,GO:0099120,GO:1901700,GO:1902168,GO:1905395	-	-	-	-	-	-	-	-	-	-	Dicty_CTDC
CMS3_k127_275535_18	300852.55772942	8.04e-44	168.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_275535_15	868595.Desca_1282	2.494e-49	183.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25ZXR@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_275535_25	886293.Sinac_1493	2.014e-11	68.0	COG1758@1|root,COG1758@2|Bacteria,2J0KS@203682|Planctomycetes	203682|Planctomycetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS3_k127_275535_17	1121472.AQWN01000003_gene1425	3.118e-48	179.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,261KT@186807|Peptococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS3_k127_275535_13	530564.Psta_3126	1.742e-54	202.0	COG1561@1|root,COG1561@2|Bacteria,2IYZH@203682|Planctomycetes	203682|Planctomycetes	S	stress-induced protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS3_k127_275535_22	1123508.JH636439_gene1358	1.846e-13	78.0	COG1314@1|root,COG1314@2|Bacteria,2J0NU@203682|Planctomycetes	203682|Planctomycetes	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS3_k127_275535_8	648996.Theam_0655	3.896e-75	262.0	COG0149@1|root,COG0149@2|Bacteria,2G4FH@200783|Aquificae	200783|Aquificae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS3_k127_275535_2	886293.Sinac_1488	8.519e-127	417.0	COG2876@1|root,COG2876@2|Bacteria,2IWU9@203682|Planctomycetes	203682|Planctomycetes	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS3_k127_275535_3	479434.Sthe_0979	4.627e-123	407.0	COG0128@1|root,COG0128@2|Bacteria,2G6S6@200795|Chloroflexi,27Y0N@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS3_k127_275535_6	1142394.PSMK_19810	4.302e-88	300.0	COG1868@1|root,COG1868@2|Bacteria,2IY74@203682|Planctomycetes	203682|Planctomycetes	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
CMS3_k127_2758226_2	234267.Acid_7572	6.635e-164	550.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_2758226_0	234267.Acid_3938	1.763e-170	573.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_2758226_1	1142394.PSMK_15140	1.204e-169	550.0	COG0043@1|root,COG0043@2|Bacteria,2IYCA@203682|Planctomycetes	203682|Planctomycetes	H	COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CMS3_k127_2758226_3	382464.ABSI01000010_gene3722	2.397e-25	106.0	COG1028@1|root,COG1028@2|Bacteria	382464.ABSI01000010_gene3722|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_275881_5	1279017.AQYJ01000021_gene2845	2.833e-05	54.0	COG2374@1|root,COG3391@1|root,COG5184@1|root,COG2374@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CHU_C,Exo_endo_phos,LTD,Reprolysin_4,TSP_3
CMS3_k127_275881_0	443143.GM18_0341	1.586e-286	921.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_275881_4	292459.STH1184	3.921e-11	78.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1VNAP@1239|Firmicutes,24W68@186801|Clostridia	186801|Clostridia	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
CMS3_k127_275881_2	1489678.RDMS_12355	3.361e-14	77.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2
CMS3_k127_275881_1	311424.DhcVS_1515	3.135e-167	535.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,34CW8@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
CMS3_k127_2763836_1	1316936.K678_06275	1.424e-19	94.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,2U9KJ@28211|Alphaproteobacteria,2JTT8@204441|Rhodospirillales	204441|Rhodospirillales	K	transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
CMS3_k127_2763836_0	861299.J421_6105	6.717e-76	280.0	COG0308@1|root,COG0739@1|root,COG0308@2|Bacteria,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K08642,ko:K21472	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,Peptidase_M1,Peptidase_M23
CMS3_k127_2763836_4	573.JG24_19305	2.517e-09	66.0	COG1309@1|root,COG1309@2|Bacteria,1RCI9@1224|Proteobacteria,1S3KX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2763836_3	1460634.JCM19037_296	6.814e-16	85.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli	91061|Bacilli	K	Transcriptional	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS3_k127_2763836_2	398767.Glov_3106	6.372e-16	78.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,43BJ5@68525|delta/epsilon subdivisions,2X713@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_276665_0	1303518.CCALI_01700	5.097e-137	450.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	prpD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
CMS3_k127_276665_1	324602.Caur_0299	2.475e-23	110.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_2779719_2	314230.DSM3645_13830	6.921e-110	367.0	COG1641@1|root,COG1641@2|Bacteria,2IXMJ@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS3_k127_2779719_5	1442599.JAAN01000047_gene2927	1.178e-73	265.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1X3DW@135614|Xanthomonadales	135614|Xanthomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS3_k127_2779719_3	1121123.AUAO01000002_gene331	6.35e-82	286.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,2KFBY@204458|Caulobacterales	204458|Caulobacterales	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS3_k127_2779719_7	237368.SCABRO_01578	1.385e-06	60.0	2EQMR@1|root,33I7Q@2|Bacteria,2J1A3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2779719_10	573370.DMR_01160	0.0004013	49.0	COG0582@1|root,COG0582@2|Bacteria,1MVZB@1224|Proteobacteria,42M9T@68525|delta/epsilon subdivisions,2WNVF@28221|Deltaproteobacteria,2M8MI@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
CMS3_k127_2779719_4	243090.RB10160	7.602e-78	295.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8,WD40
CMS3_k127_2779719_1	926554.KI912680_gene831	1.407e-110	381.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
CMS3_k127_2779719_6	1500301.JQMF01000008_gene921	3.97e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria,4BC79@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2779719_0	945713.IALB_1293	4.881e-189	623.0	COG1523@1|root,COG4935@1|root,COG1523@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PUD,Reprolysin_4
CMS3_k127_2814061_8	33905.BTHE_0915	6.692e-55	218.0	COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CZAK@85004|Bifidobacteriales	201174|Actinobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS3_k127_2814061_6	1210884.HG799462_gene8108	1.171e-80	293.0	COG1162@1|root,COG1162@2|Bacteria,2IXC9@203682|Planctomycetes	203682|Planctomycetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CMS3_k127_2814061_2	756272.Plabr_1378	3.226e-103	356.0	COG0482@1|root,COG0482@2|Bacteria,2IXFF@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS3_k127_2814061_3	502025.Hoch_6778	4.878e-100	340.0	COG0491@1|root,COG0491@2|Bacteria,1Q2NG@1224|Proteobacteria,4389J@68525|delta/epsilon subdivisions,2X3IZ@28221|Deltaproteobacteria,2YWA6@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_2814061_13	1142394.PSMK_21880	1.339e-20	103.0	COG0859@1|root,COG0859@2|Bacteria,2J4DC@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CMS3_k127_2814061_1	1123508.JH636441_gene3383	3.933e-126	411.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS3_k127_2814061_9	237368.SCABRO_03329	3.209e-47	184.0	COG1354@1|root,COG1354@2|Bacteria,2IZIR@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS3_k127_2814061_10	1171373.PACID_29140	4.089e-45	168.0	COG0251@1|root,COG0251@2|Bacteria,2IHNE@201174|Actinobacteria,4DQIS@85009|Propionibacteriales	201174|Actinobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	yabJ	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS3_k127_2814061_7	1515746.HR45_18865	1.562e-58	220.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,2Q9JH@267890|Shewanellaceae	1236|Gammaproteobacteria	MU	PFAM Peptidoglycan-binding domain 1 protein	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1,T2SSB
CMS3_k127_2814061_14	240016.ABIZ01000001_gene5347	2.92e-14	83.0	COG1596@1|root,COG1596@2|Bacteria,46XCW@74201|Verrucomicrobia,2IVGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
CMS3_k127_2814061_12	246197.MXAN_3228	6.47e-26	119.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,42QS3@68525|delta/epsilon subdivisions,2WMX0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Capsular exopolysaccharide family	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CbiA,ParA
CMS3_k127_2814061_5	177437.HRM2_19860	1.117e-97	333.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,42PY5@68525|delta/epsilon subdivisions,2WIU8@28221|Deltaproteobacteria,2MMRN@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	tuaH	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
CMS3_k127_2814061_11	644966.Tmar_1416	5.102e-45	171.0	COG0108@1|root,COG0307@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0307@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WCXY@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
CMS3_k127_2814061_4	1142394.PSMK_11860	4.022e-98	338.0	COG1995@1|root,COG1995@2|Bacteria,2IYEZ@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the PdxA family	pdxA	-	1.1.1.408,1.1.1.409	ko:K22024	-	-	-	-	ko00000,ko01000	-	-	-	PdxA
CMS3_k127_2814061_0	472759.Nhal_2900	0.0	1149.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS3_k127_2816162_1	247639.MGP2080_08856	1.055e-56	201.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,1S1KW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS3_k127_2816162_0	314285.KT71_01220	5.019e-163	517.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria,1J9CZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
CMS3_k127_2841895_18	96561.Dole_0842	6.171e-07	62.0	COG3209@1|root,COG3386@1|root,COG3209@2|Bacteria,COG3386@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2MN6Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
CMS3_k127_2841895_15	272563.CD630_36790	3.243e-17	87.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,25RS0@186804|Peptostreptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS3_k127_2841895_3	661478.OP10G_1178	7.298e-139	468.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
CMS3_k127_2841895_4	1210884.HG799462_gene8747	1.574e-114	385.0	COG0074@1|root,COG0074@2|Bacteria,2IWYV@203682|Planctomycetes	203682|Planctomycetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS3_k127_2841895_11	1128421.JAGA01000003_gene3620	6.197e-46	171.0	COG2947@1|root,COG2947@2|Bacteria,2NPYZ@2323|unclassified Bacteria	2|Bacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS3_k127_2841895_17	472759.Nhal_1412	5.207e-08	64.0	COG1266@1|root,COG1266@2|Bacteria,1NMQX@1224|Proteobacteria,1T0K0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2841895_14	35754.JNYJ01000003_gene6473	1.657e-17	93.0	COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria,4DER8@85008|Micromonosporales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2841895_5	575540.Isop_1517	5.023e-113	378.0	COG0513@1|root,COG0513@2|Bacteria,2IX02@203682|Planctomycetes	203682|Planctomycetes	JKL	DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
CMS3_k127_2841895_8	247490.KSU1_D0086	3.332e-77	271.0	COG0564@1|root,COG0564@2|Bacteria,2IXSI@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_2841895_2	243090.RB9927	5.743e-165	530.0	COG1219@1|root,COG1219@2|Bacteria,2IXDS@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS3_k127_2841895_6	1142394.PSMK_10550	3.019e-93	326.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2IXA1@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA
CMS3_k127_2841895_16	1123242.JH636435_gene1925	5.166e-08	65.0	COG1600@1|root,COG3255@1|root,COG1600@2|Bacteria,COG3255@2|Bacteria,2J2R7@203682|Planctomycetes	203682|Planctomycetes	CI	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,SCP2
CMS3_k127_2841895_19	379731.PST_3844	8.612e-07	61.0	COG0515@1|root,COG0515@2|Bacteria,1RJDC@1224|Proteobacteria,1SBNM@1236|Gammaproteobacteria,1Z1E0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
CMS3_k127_2841895_0	756272.Plabr_2313	2.47e-269	864.0	COG0841@1|root,COG0841@2|Bacteria,2IYJA@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_2841895_12	756272.Plabr_3951	3.78e-34	147.0	COG1566@1|root,COG1566@2|Bacteria,2IYYK@203682|Planctomycetes	2|Bacteria	V	multidrug resistance efflux pump	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_2841895_10	344747.PM8797T_13103	3.936e-69	267.0	COG1452@1|root,COG1452@2|Bacteria,2IXFV@203682|Planctomycetes	203682|Planctomycetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OstA_C
CMS3_k127_2841895_1	575540.Isop_0731	6.892e-226	714.0	COG0481@1|root,COG0481@2|Bacteria,2IXI5@203682|Planctomycetes	203682|Planctomycetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS3_k127_2841895_9	525897.Dbac_1689	7.52e-73	262.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42P9R@68525|delta/epsilon subdivisions,2WJAD@28221|Deltaproteobacteria,2MG9B@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_2841895_13	1463887.KL589954_gene7191	8.026e-28	119.0	COG2318@1|root,COG2318@2|Bacteria,2GXK3@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_2841895_7	243231.GSU0769	1.62e-91	309.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
CMS3_k127_2919693_0	1396141.BATP01000005_gene6002	5.751e-77	273.0	COG2931@1|root,COG2931@2|Bacteria,46UDY@74201|Verrucomicrobia,2IWGN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2919693_1	483219.LILAB_18890	1.829e-07	62.0	COG3391@1|root,COG3391@2|Bacteria,1P80Y@1224|Proteobacteria,43959@68525|delta/epsilon subdivisions,2X4BM@28221|Deltaproteobacteria,2YYPB@29|Myxococcales	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2946905_0	595460.RRSWK_03500	2.465e-68	244.0	COG3391@1|root,COG3391@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
CMS3_k127_2946905_1	575540.Isop_2740	2.376e-47	183.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
CMS3_k127_2951236_12	671143.DAMO_1304	3.5e-82	297.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_2951236_7	309801.trd_1715	2.749e-119	407.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_2951236_9	330214.NIDE3611	2.771e-98	333.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
CMS3_k127_2951236_13	261292.Nit79A3_2848	2.644e-64	232.0	COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria,373WJ@32003|Nitrosomonadales	28216|Betaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS3_k127_2951236_5	1232410.KI421415_gene2974	6.029e-154	500.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS3_k127_2951236_1	1232410.KI421415_gene2975	9.618e-195	623.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
CMS3_k127_2951236_11	1232410.KI421415_gene2976	4.202e-85	293.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,43SVV@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
CMS3_k127_2951236_4	879212.DespoDRAFT_00577	6.94e-157	504.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria,2MHP9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
CMS3_k127_2951236_8	926550.CLDAP_04870	2.936e-112	409.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_2951236_10	1121396.KB892946_gene2917	2.737e-92	345.0	COG0823@1|root,COG3291@1|root,COG3591@1|root,COG4676@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3591@2|Bacteria,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	Germane,Gmad1
CMS3_k127_2951236_2	1210884.HG799462_gene8559	3.499e-172	557.0	COG2804@1|root,COG2804@2|Bacteria,2IXSA@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_2951236_3	756272.Plabr_2546	3.305e-159	509.0	COG2805@1|root,COG2805@2|Bacteria,2IXRP@203682|Planctomycetes	203682|Planctomycetes	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_2951236_0	1142394.PSMK_20220	6.311e-232	732.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_2951236_6	1142394.PSMK_20230	7.782e-138	450.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_2951236_15	794903.OPIT5_24515	3.207e-06	59.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS3_k127_2951236_14	583355.Caka_0253	5.585e-08	65.0	COG2165@1|root,COG2165@2|Bacteria,46YQC@74201|Verrucomicrobia,3K9ZW@414999|Opitutae	414999|Opitutae	U	N-terminal cleavage protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS3_k127_2957138_7	1303518.CCALI_02808	2.566e-07	64.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2957138_5	1157637.KB892092_gene6952	1.209e-16	84.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_2957138_2	530564.Psta_3875	8.528e-135	443.0	COG1524@1|root,COG1524@2|Bacteria,2IXT6@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_2957138_4	530564.Psta_3876	5.595e-85	295.0	COG1082@1|root,COG1082@2|Bacteria,2IYC6@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_2957138_6	1122622.ATWJ01000001_gene2442	1.828e-07	63.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634,ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	Cadherin,LolA,PPC
CMS3_k127_2957138_8	1120950.KB892739_gene3949	6.758e-05	55.0	2C49Q@1|root,32RRD@2|Bacteria,2HSWF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2957138_1	635013.TherJR_1006	4.363e-173	590.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,2606F@186807|Peptococcaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_2957138_0	1123242.JH636435_gene2905	1.277e-286	912.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,2IX0I@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
CMS3_k127_2957138_3	926550.CLDAP_04870	4.112e-99	350.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_2969177_0	1519464.HY22_13125	4.993e-113	392.0	COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
CMS3_k127_2981309_1	1121920.AUAU01000008_gene1614	8.854e-63	225.0	COG0437@1|root,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	2|Bacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molydop_binding
CMS3_k127_2981309_2	1348583.ATLH01000029_gene1340	1.641e-48	181.0	COG4654@1|root,COG4654@2|Bacteria,4PMBX@976|Bacteroidetes,1IJR5@117743|Flavobacteriia,1F803@104264|Cellulophaga	976|Bacteroidetes	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C7
CMS3_k127_2981309_0	523791.Kkor_1344	5.367e-174	561.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,1XHV1@135619|Oceanospirillales	135619|Oceanospirillales	P	nitrate nitrite transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
CMS3_k127_3001215_2	709991.Odosp_3403	5.333e-09	67.0	COG0526@1|root,COG0526@2|Bacteria,4NNY5@976|Bacteroidetes	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CMS3_k127_3001215_3	743718.Isova_0576	2.989e-08	65.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4F3ZP@85017|Promicromonosporaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	degP	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3001215_0	644282.Deba_3187	3.482e-317	981.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_3001215_1	477228.YO5_18747	4.165e-25	109.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1Z0PU@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
CMS3_k127_3004077_3	1385510.N781_02360	0.0005061	44.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,4H9VP@91061|Bacilli,2Y9XP@289201|Pontibacillus	91061|Bacilli	Q	Amidohydrolase	hutI	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_3004077_2	1173020.Cha6605_3014	1.219e-05	52.0	2EKKN@1|root,33EAG@2|Bacteria,1GFDS@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3004077_1	644282.Deba_1899	8.261e-83	292.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_3004077_0	1303518.CCALI_02927	5.8e-114	376.0	COG0059@1|root,COG0059@2|Bacteria	2|Bacteria	EH	ketol-acid reductoisomerase activity	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iHN637.CLJU_RS07505,iHN637.CLJU_RS10005,iHN637.CLJU_RS10010,iIT341.HP0330,iJN746.PP_4678,iLF82_1304.LF82_1103,iLJ478.TM0550	IlvC,IlvN
CMS3_k127_3011389_2	335543.Sfum_1621	2.965e-31	142.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
CMS3_k127_3011389_0	335543.Sfum_1622	7.447e-207	676.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C554
CMS3_k127_3011389_1	335543.Sfum_1624	1.844e-63	237.0	COG0823@1|root,COG0823@2|Bacteria,1PFBB@1224|Proteobacteria,432XJ@68525|delta/epsilon subdivisions,2WXKI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3015887_1	1279009.ADICEAN_03078	9.458e-137	449.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes,47P0R@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
CMS3_k127_3015887_4	857087.Metme_2233	1.436e-65	253.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XGE2@135618|Methylococcales	135618|Methylococcales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3015887_7	395493.BegalDRAFT_0270	8.929e-61	238.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,460PZ@72273|Thiotrichales	72273|Thiotrichales	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS3_k127_3015887_0	1303518.CCALI_01053	1.323e-140	492.0	COG0642@1|root,COG0784@1|root,COG1807@1|root,COG2198@1|root,COG2202@1|root,COG5000@1|root,COG0784@2|Bacteria,COG1807@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	barA	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg,dCache_1
CMS3_k127_3015887_13	1163617.SCD_n02076	4.589e-06	58.0	COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,2VSU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transport system periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS3_k127_3015887_6	671143.DAMO_1264	3.267e-61	237.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS3_k127_3015887_5	530564.Psta_3458	1.713e-61	220.0	COG1416@1|root,COG4798@1|root,COG1416@2|Bacteria,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
CMS3_k127_3015887_12	1150864.MILUP08_42886	1.948e-06	51.0	COG0662@1|root,COG0662@2|Bacteria,2INXJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_3015887_8	883126.HMPREF9710_02359	1.891e-53	196.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2VS3X@28216|Betaproteobacteria,474FC@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_3015887_11	5762.XP_002672201.1	6.016e-14	83.0	KOG1225@1|root,KOG3637@1|root,KOG4297@1|root,KOG1225@2759|Eukaryota,KOG3637@2759|Eukaryota,KOG4297@2759|Eukaryota	2759|Eukaryota	S	carbohydrate binding	VWDE	-	-	-	-	-	-	-	-	-	-	-	EGF,EGF_2,FG-GAP,Integrin_alpha2,Pkinase_Tyr,VCBS,VWA,VWD
CMS3_k127_3015887_9	1396141.BATP01000047_gene3875	1.69e-50	192.0	COG1404@1|root,COG1404@2|Bacteria,46VVV@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3015887_10	863365.XHC_1075	6.09e-40	151.0	COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,1S5G6@1236|Gammaproteobacteria,1X6C8@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_3015887_3	485918.Cpin_4405	6.728e-106	360.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IVAH@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3
CMS3_k127_3015887_2	1125863.JAFN01000001_gene1578	3.735e-133	428.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
CMS3_k127_3027804_2	1089548.KI783301_gene1385	2.967e-75	263.0	COG0438@1|root,COG0438@2|Bacteria,1TS5D@1239|Firmicutes,4HWXP@91061|Bacilli	91061|Bacilli	M	Glycosyl transferases group 1	PIGA	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3027804_1	1267533.KB906738_gene2028	6.494e-136	439.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
CMS3_k127_3027804_0	909663.KI867150_gene2728	4.376e-230	743.0	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria,2MR0K@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3027804_4	665577.JH993790_gene4853	9.841e-06	58.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_1,Thioredoxin_4
CMS3_k127_3027804_3	926550.CLDAP_16140	7.547e-56	208.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
CMS3_k127_3027804_5	493475.GARC_1577	0.0001259	47.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,1SG7D@1236|Gammaproteobacteria,468J7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_3038083_31	530564.Psta_3014	4.443e-07	56.0	COG4969@1|root,COG4969@2|Bacteria,2J2XQ@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_3038083_8	1267533.KB906733_gene3472	2.035e-91	322.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_3038083_27	913865.DOT_2199	4.647e-16	87.0	COG1595@1|root,COG1595@2|Bacteria,1VEYQ@1239|Firmicutes,24S3D@186801|Clostridia,264EN@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3038083_4	983544.Lacal_1859	3.28e-109	394.0	COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria,4NF8H@976|Bacteroidetes,1HY9Y@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
CMS3_k127_3038083_30	1430440.MGMSRv2_1160	2.039e-10	64.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,2JTZ3@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS3_k127_3038083_11	1142394.PSMK_17290	3.841e-90	307.0	COG0416@1|root,COG0416@2|Bacteria,2IWUY@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS3_k127_3038083_6	580331.Thit_1283	1.588e-98	333.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_3038083_15	756272.Plabr_2508	2.972e-78	273.0	COG0331@1|root,COG0331@2|Bacteria,2IXX2@203682|Planctomycetes	203682|Planctomycetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS3_k127_3038083_14	1142394.PSMK_22760	2.747e-79	271.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_3038083_25	886293.Sinac_1364	2.906e-25	106.0	COG0236@1|root,COG0236@2|Bacteria,2J0V5@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_3038083_1	595460.RRSWK_01782	1.769e-153	495.0	COG0304@1|root,COG0304@2|Bacteria,2IWRA@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_3038083_28	530564.Psta_2237	1.755e-13	76.0	COG1886@1|root,COG1886@2|Bacteria,2J11H@203682|Planctomycetes	203682|Planctomycetes	N	COG1886 Flagellar motor switch type III secretory pathway	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
CMS3_k127_3038083_16	344747.PM8797T_01579	8.384e-76	272.0	COG0617@1|root,COG0617@2|Bacteria,2IXYM@203682|Planctomycetes	203682|Planctomycetes	H	tRNA nucleotidyltransferase poly(A) polymerase	papS	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
CMS3_k127_3038083_24	1123269.NX02_14220	5.016e-29	124.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,2K3X3@204457|Sphingomonadales	204457|Sphingomonadales	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS3_k127_3038083_23	314230.DSM3645_07450	1.777e-33	134.0	COG0727@1|root,COG0727@2|Bacteria,2IZU5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
CMS3_k127_3038083_20	314230.DSM3645_07440	1.744e-35	145.0	2E296@1|root,32XEW@2|Bacteria,2J070@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3038083_12	1125863.JAFN01000001_gene836	1.306e-82	289.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
CMS3_k127_3038083_35	1077972.ARGLB_027_00200	0.0006717	49.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR9	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS3_k127_3038083_26	1210884.HG799465_gene12149	4.985e-22	107.0	2EPQ7@1|root,33HAS@2|Bacteria,2J1P9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3038083_18	530564.Psta_2581	5.752e-63	226.0	COG1211@1|root,COG1211@2|Bacteria,2IYXJ@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CMS3_k127_3038083_5	575540.Isop_2719	1.751e-100	345.0	COG4956@1|root,COG4956@2|Bacteria,2IXF3@203682|Planctomycetes	203682|Planctomycetes	S	Integral membrane protein (PIN domain superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	PIN_4,TRAM
CMS3_k127_3038083_9	521674.Plim_3815	1.681e-90	316.0	COG0534@1|root,COG0534@2|Bacteria,2IXGS@203682|Planctomycetes	203682|Planctomycetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS3_k127_3038083_10	886293.Sinac_2703	2.489e-90	308.0	COG0240@1|root,COG0240@2|Bacteria,2IWWN@203682|Planctomycetes	203682|Planctomycetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS3_k127_3038083_29	756272.Plabr_4525	1.208e-12	80.0	2E5SS@1|root,330H5@2|Bacteria,2J0J5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3038083_7	1089553.Tph_c20550	1.067e-94	329.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,42FM5@68295|Thermoanaerobacterales	186801|Clostridia	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
CMS3_k127_3038083_19	1142394.PSMK_19370	1.38e-47	186.0	COG0115@1|root,COG0115@2|Bacteria,2IY3N@203682|Planctomycetes	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_3038083_13	1123508.JH636449_gene7387	1.647e-80	284.0	COG0327@1|root,COG0327@2|Bacteria,2IXMR@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM dinuclear metal center protein, YbgI SA1388 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS3_k127_3038083_21	1267533.KB906738_gene2142	2.278e-35	148.0	COG3920@1|root,COG4191@1|root,COG3920@2|Bacteria,COG4191@2|Bacteria,3Y7B2@57723|Acidobacteria,2JKKQ@204432|Acidobacteriia	204432|Acidobacteriia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS
CMS3_k127_3038083_33	530564.Psta_0848	2.745e-05	56.0	2EN6E@1|root,33FU9@2|Bacteria,2J1D6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3038083_34	246969.TAM4_2114	0.00013	51.0	COG1633@1|root,arCOG03797@1|root,arCOG01104@2157|Archaea,arCOG03797@2157|Archaea,2Y37M@28890|Euryarchaeota,243GK@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	DUF835,Rubrerythrin
CMS3_k127_3038083_0	290397.Adeh_0285	1.952e-165	541.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2YWSD@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS3_k127_3038083_32	3659.XP_004172328.1	5.819e-07	55.0	COG2217@1|root,KOG0207@2759|Eukaryota,37HKS@33090|Viridiplantae,3G75W@35493|Streptophyta,4JD8R@91835|fabids	35493|Streptophyta	P	Copper-transporting ATPase	RAN1	GO:0000160,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0007154,GO:0007165,GO:0008150,GO:0009719,GO:0009723,GO:0009725,GO:0009755,GO:0009873,GO:0009987,GO:0010033,GO:0010119,GO:0012505,GO:0016020,GO:0023052,GO:0031410,GO:0031982,GO:0031984,GO:0032870,GO:0035556,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071369,GO:0071495,GO:0097708,GO:0098791	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_3038083_2	396588.Tgr7_0441	6.809e-148	494.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WVXM@135613|Chromatiales	135613|Chromatiales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_3038083_17	1223410.KN050846_gene1961	5.197e-68	261.0	COG4935@1|root,COG5276@1|root,COG4935@2|Bacteria,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_3038083_3	926550.CLDAP_04870	1.875e-111	383.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_3038083_22	1278073.MYSTI_02465	1.246e-33	133.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_3043709_1	1116375.VEJY3_21596	2.399e-39	170.0	COG4932@1|root,COG4932@2|Bacteria,1R944@1224|Proteobacteria,1S165@1236|Gammaproteobacteria,1Y09R@135623|Vibrionales	135623|Vibrionales	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3043709_4	1144275.COCOR_03766	2.115e-10	75.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,1P5GC@1224|Proteobacteria,433PX@68525|delta/epsilon subdivisions,2WYIK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_3043709_0	595460.RRSWK_00132	2.475e-42	160.0	COG0817@1|root,COG0817@2|Bacteria,2IZJS@203682|Planctomycetes	203682|Planctomycetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS3_k127_3043709_2	314230.DSM3645_19198	3.594e-28	127.0	COG0632@1|root,COG0632@2|Bacteria,2IZ2E@203682|Planctomycetes	203682|Planctomycetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS3_k127_304681_7	1223410.KN050846_gene2603	3.087e-34	135.0	COG3844@1|root,COG3844@2|Bacteria,4NECS@976|Bacteroidetes,1HWY8@117743|Flavobacteriia	976|Bacteroidetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS3_k127_304681_0	523791.Kkor_0379	1.109e-165	526.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,1RX6Z@1236|Gammaproteobacteria,1XRR2@135619|Oceanospirillales	135619|Oceanospirillales	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
CMS3_k127_304681_2	234267.Acid_2488	3.953e-61	219.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_304681_1	983544.Lacal_1459	1.318e-65	228.0	COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,1HX5C@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	-	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
CMS3_k127_304681_5	661478.OP10G_1970	2.882e-40	169.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CMS3_k127_304681_6	1198232.CYCME_0174	7.563e-36	146.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,4602G@72273|Thiotrichales	72273|Thiotrichales	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
CMS3_k127_304681_3	754477.Q7C_1123	6.624e-43	171.0	COG3137@1|root,COG3137@2|Bacteria,1QSGG@1224|Proteobacteria,1RVWA@1236|Gammaproteobacteria,4624V@72273|Thiotrichales	72273|Thiotrichales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
CMS3_k127_304681_4	192952.MM_0502	3.917e-42	160.0	COG0251@1|root,arCOG01630@2157|Archaea,2Y700@28890|Euryarchaeota,2NAY2@224756|Methanomicrobia	224756|Methanomicrobia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_304681_8	1121129.KB903360_gene3091	4.947e-27	114.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia,22XIU@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CMS3_k127_3047103_0	946362.XP_004997743.1	2.884e-187	623.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_3047103_1	886293.Sinac_3283	2.079e-68	239.0	COG0624@1|root,COG0624@2|Bacteria,2IXPJ@203682|Planctomycetes	203682|Planctomycetes	E	ArgE DapE Acy1 family protein	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_3050207_2	1121920.AUAU01000001_gene2303	3.203e-07	51.0	COG1505@1|root,COG1505@2|Bacteria,3Y2UH@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9A, prolyl oligopeptidase domain protein beta-propeller	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_3050207_1	153721.MYP_563	2.457e-36	159.0	COG2373@1|root,COG3055@1|root,COG3386@1|root,COG4099@1|root,COG4733@1|root,COG2373@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,COG4099@2|Bacteria,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PA14,fn3
CMS3_k127_3050207_3	1384057.CD33_09225	5.841e-06	60.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,1VKCH@1239|Firmicutes,4IS68@91061|Bacilli,3IVNH@400634|Lysinibacillus	91061|Bacilli	L	Chitobiase/beta-hexosaminidase C-terminal domain	XK27_02140	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHB_HEX_C_1,Endonuclease_1,Exo_endo_phos,Gram_pos_anchor,LTD
CMS3_k127_3050207_0	204669.Acid345_3122	7.575e-147	495.0	COG0383@1|root,COG0383@2|Bacteria,3Y2RJ@57723|Acidobacteria,2JI5W@204432|Acidobacteriia	204432|Acidobacteriia	G	glycoside hydrolase family 38	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS3_k127_3058872_7	234267.Acid_7677	7.917e-46	174.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_3058872_0	1267533.KB906733_gene3472	1.651e-169	569.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_3058872_1	313606.M23134_02003	1.196e-160	519.0	COG0179@1|root,COG0179@2|Bacteria,4NGI0@976|Bacteroidetes,47KTT@768503|Cytophagia	976|Bacteroidetes	Q	fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
CMS3_k127_3058872_8	584708.Apau_1194	1.426e-14	86.0	COG1520@1|root,COG1520@2|Bacteria,3TB0M@508458|Synergistetes	508458|Synergistetes	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_3058872_2	93220.LV28_10985	5.975e-145	477.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,1K3VV@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS3_k127_3058872_6	1521187.JPIM01000019_gene365	1.833e-46	173.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,3777D@32061|Chloroflexia	32061|Chloroflexia	S	PFAM cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS3_k127_3058872_9	1335757.SPICUR_09115	6.164e-06	60.0	COG3307@1|root,COG3307@2|Bacteria,1R8PC@1224|Proteobacteria,1RYYV@1236|Gammaproteobacteria,1X092@135613|Chromatiales	135613|Chromatiales	M	O-antigen ligase like membrane protein	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
CMS3_k127_3058872_5	926554.KI912633_gene4050	1.65e-52	199.0	COG4124@1|root,COG4124@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_26
CMS3_k127_3058872_4	670487.Ocepr_0862	2.785e-60	226.0	COG0612@1|root,COG0612@2|Bacteria,1WIM9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_3058872_3	526227.Mesil_1462	2.386e-73	264.0	COG0612@1|root,COG0612@2|Bacteria,1WIJ5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_3066952_5	1123508.JH636439_gene1547	1.779e-07	59.0	COG0178@1|root,COG0178@2|Bacteria,2IXFK@203682|Planctomycetes	203682|Planctomycetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_3066952_3	314230.DSM3645_11457	9.348e-38	151.0	2BM0T@1|root,32FHQ@2|Bacteria,2IZTI@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3066952_0	1123508.JH636439_gene1797	3.424e-216	694.0	COG0441@1|root,COG0441@2|Bacteria,2IXFR@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS3_k127_3066952_2	575540.Isop_0475	1.451e-45	172.0	COG0290@1|root,COG0290@2|Bacteria,2IZ68@203682|Planctomycetes	203682|Planctomycetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS3_k127_3066952_1	195250.CM001776_gene3850	2.697e-130	426.0	COG2046@1|root,COG2046@2|Bacteria,1G0E8@1117|Cyanobacteria,1GZIH@1129|Synechococcus	1117|Cyanobacteria	P	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
CMS3_k127_3066952_4	479434.Sthe_1259	6.348e-20	97.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi,27Y2D@189775|Thermomicrobia	189775|Thermomicrobia	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_3106137_0	1267535.KB906767_gene4789	1.062e-127	416.0	COG1064@1|root,COG1064@2|Bacteria,3Y34K@57723|Acidobacteria,2JIU5@204432|Acidobacteriia	204432|Acidobacteriia	S	Zinc-binding alcohol dehydrogenase family protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
CMS3_k127_3106137_3	1249627.D779_0725	2.331e-26	124.0	COG2931@1|root,COG3291@1|root,COG4447@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,1PGW0@1224|Proteobacteria,1TM54@1236|Gammaproteobacteria,1X0IA@135613|Chromatiales	135613|Chromatiales	Q	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3106137_1	1123278.KB893427_gene1235	5.777e-40	170.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3106137_2	1457250.BBMO01000002_gene2310	4.171e-32	145.0	COG0419@1|root,arCOG00368@2157|Archaea	2157|Archaea	L	Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex	-	-	-	-	-	-	-	-	-	-	-	-	MMPL,PQQ_2,Peptidase_S74,Pkinase
CMS3_k127_3106304_0	1142394.PSMK_16820	2.337e-148	499.0	COG0210@1|root,COG0210@2|Bacteria,2IWTI@203682|Planctomycetes	203682|Planctomycetes	L	COG0210 Superfamily I DNA and RNA	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_3106304_2	1123242.JH636437_gene6054	1.889e-13	77.0	COG0736@1|root,COG0736@2|Bacteria,2IZSD@203682|Planctomycetes	203682|Planctomycetes	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_3106304_3	204669.Acid345_4518	5.85e-05	47.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia	204432|Acidobacteriia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_3106304_1	497321.C664_13307	4.306e-82	284.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2VK9J@28216|Betaproteobacteria,2KUE1@206389|Rhodocyclales	206389|Rhodocyclales	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
CMS3_k127_3125539_0	880073.Calab_2545	1.377e-77	290.0	COG1404@1|root,COG2911@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Autotransporter,Peptidase_S8,Peptidase_S8_N
CMS3_k127_3132123_1	160860.XP_007351742.1	1.745e-44	170.0	2E2W8@1|root,2SA2G@2759|Eukaryota,3A9FS@33154|Opisthokonta,3P7Z9@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
CMS3_k127_3132123_0	102125.Xen7305DRAFT_00025450	4.748e-73	268.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
CMS3_k127_3146297_2	1173027.Mic7113_1845	8.416e-244	768.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria,1H8JB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_3146297_8	1123508.JH636442_gene4111	6.071e-90	325.0	COG1361@1|root,COG1361@2|Bacteria,2IZ0N@203682|Planctomycetes	203682|Planctomycetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_3146297_19	269799.Gmet_1014	4.118e-51	199.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3146297_37	754331.AEME01000001_gene106	9.415e-07	57.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,1RRDM@1236|Gammaproteobacteria,3XMQH@561|Escherichia	1236|Gammaproteobacteria	S	Belongs to the UPF0149 family	yecA	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
CMS3_k127_3146297_12	667014.Thein_0048	8.163e-72	257.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,2GH0E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS3_k127_3146297_6	344747.PM8797T_12568	3.329e-110	365.0	COG2107@1|root,COG2107@2|Bacteria,2IXIY@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CMS3_k127_3146297_3	1123508.JH636442_gene4220	2.772e-202	656.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_3146297_0	330214.NIDE2582	8.735e-297	951.0	COG0587@1|root,COG0587@2|Bacteria,3J0FE@40117|Nitrospirae	40117|Nitrospirae	L	DNA-directed DNA polymerase	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_3146297_29	1380390.JIAT01000011_gene2640	3.818e-16	87.0	COG1595@1|root,COG1595@2|Bacteria,2HXZ9@201174|Actinobacteria,4CQ7U@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3146297_36	1541065.JRFE01000006_gene4739	1.161e-08	68.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,3VKZ2@52604|Pleurocapsales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3146297_7	880072.Desac_1935	1.186e-106	356.0	COG2006@1|root,COG2006@2|Bacteria,1R7BH@1224|Proteobacteria,42QGJ@68525|delta/epsilon subdivisions,2WJ1A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_3146297_17	886293.Sinac_1934	3.765e-53	200.0	COG1657@1|root,COG1657@2|Bacteria,2J0IG@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3146297_38	1123508.JH636443_gene4895	3.691e-06	51.0	COG3847@1|root,COG3847@2|Bacteria,2J15T@203682|Planctomycetes	203682|Planctomycetes	U	Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS3_k127_3146297_33	338963.Pcar_3316	9.022e-11	66.0	2CB4N@1|root,2ZUIQ@2|Bacteria,1Q1QS@1224|Proteobacteria,43EYF@68525|delta/epsilon subdivisions,2X2KD@28221|Deltaproteobacteria,43VWB@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3146297_35	530564.Psta_2070	4.914e-10	62.0	COG3847@1|root,COG3847@2|Bacteria,2J15T@203682|Planctomycetes	203682|Planctomycetes	U	Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS3_k127_3146297_27	756272.Plabr_1523	6.917e-22	102.0	COG4960@1|root,COG4960@2|Bacteria,2IZQF@203682|Planctomycetes	203682|Planctomycetes	OU	PFAM Peptidase A24A, prepilin type IV	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
CMS3_k127_3146297_34	909663.KI867150_gene1925	1.271e-10	69.0	COG4961@1|root,COG4961@2|Bacteria,1NGEX@1224|Proteobacteria,42XRE@68525|delta/epsilon subdivisions,2WSQQ@28221|Deltaproteobacteria,2MRVH@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS3_k127_3146297_28	1089553.Tph_c05480	4.382e-18	96.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,42H14@68295|Thermoanaerobacterales	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS3_k127_3146297_11	247490.KSU1_D0131	5.492e-80	286.0	COG4964@1|root,COG4964@2|Bacteria,2IYI6@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Secretin,T2SS-T3SS_pil_N
CMS3_k127_3146297_21	595460.RRSWK_04225	2.658e-48	188.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2IYFX@203682|Planctomycetes	203682|Planctomycetes	KTU	Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,Response_reg
CMS3_k127_3146297_5	530564.Psta_1434	1.105e-177	567.0	COG4962@1|root,COG4962@2|Bacteria,2IXAQ@203682|Planctomycetes	203682|Planctomycetes	U	Secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS3_k127_3146297_15	344747.PM8797T_20848	4.712e-58	214.0	COG4965@1|root,COG4965@2|Bacteria,2IYKD@203682|Planctomycetes	203682|Planctomycetes	U	type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS3_k127_3146297_16	521674.Plim_1916	6.824e-56	208.0	COG2064@1|root,COG2064@2|Bacteria,2IYG1@203682|Planctomycetes	203682|Planctomycetes	NU	Secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS3_k127_3146297_24	448385.sce3843	3.691e-37	155.0	COG1355@1|root,COG1355@2|Bacteria,1N5H1@1224|Proteobacteria,42TIN@68525|delta/epsilon subdivisions,2WR24@28221|Deltaproteobacteria,2Z1BF@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS3_k127_3146297_13	595460.RRSWK_02270	2.782e-71	254.0	COG1663@1|root,COG1663@2|Bacteria,2IXYX@203682|Planctomycetes	203682|Planctomycetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS3_k127_3146297_10	667014.Thein_0868	1.624e-81	287.0	COG1899@1|root,COG1899@2|Bacteria,2GIEP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3146297_22	1210884.HG799476_gene15385	3.806e-44	172.0	COG0241@1|root,COG0241@2|Bacteria,2IZYR@203682|Planctomycetes	203682|Planctomycetes	E	Polynucleotide kinase 3 phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
CMS3_k127_3146297_26	886293.Sinac_2827	2.254e-32	128.0	COG0776@1|root,COG0776@2|Bacteria,2J0XR@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
CMS3_k127_3146297_9	237368.SCABRO_01714	3.097e-84	290.0	COG0667@1|root,COG0667@2|Bacteria,2IX8H@203682|Planctomycetes	203682|Planctomycetes	C	oxidoreductases (related to aryl-alcohol	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_3146297_4	521674.Plim_0435	1.122e-197	622.0	COG0050@1|root,COG0050@2|Bacteria,2IXC2@203682|Planctomycetes	203682|Planctomycetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS3_k127_3146297_31	1142394.PSMK_08320	1.373e-13	71.0	COG0267@1|root,COG0267@2|Bacteria,2J1HX@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL33 family	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS3_k127_3146297_30	1142394.PSMK_08330	2.582e-15	82.0	COG0690@1|root,COG0690@2|Bacteria,2J0E7@203682|Planctomycetes	203682|Planctomycetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS3_k127_3146297_18	1142394.PSMK_08340	1.241e-52	194.0	COG0250@1|root,COG0250@2|Bacteria,2IZ9N@203682|Planctomycetes	203682|Planctomycetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS3_k127_3146297_20	575540.Isop_0109	6.238e-49	179.0	COG0080@1|root,COG0080@2|Bacteria,2IZ97@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS3_k127_3146297_14	247490.KSU1_C1198	1.633e-62	223.0	COG0081@1|root,COG0081@2|Bacteria,2IYQK@203682|Planctomycetes	203682|Planctomycetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS3_k127_3146297_32	525897.Dbac_2783	1.098e-11	72.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2WNX3@28221|Deltaproteobacteria,2MBSK@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS3_k127_3146297_23	756272.Plabr_2007	1.885e-37	144.0	COG0222@1|root,COG0222@2|Bacteria,2J0AK@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS3_k127_3146297_1	1142394.PSMK_24450	4.787e-270	844.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS3_k127_3151849_0	859657.RPSI07_0811	6.219e-136	475.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM Hemolysin-type calcium-binding	cyaA	GO:0001906,GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0006873,GO:0006874,GO:0006875,GO:0007204,GO:0008150,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0019725,GO:0019835,GO:0030003,GO:0031640,GO:0035821,GO:0042592,GO:0044179,GO:0044364,GO:0044419,GO:0044764,GO:0048878,GO:0050801,GO:0051480,GO:0051704,GO:0051715,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0072503,GO:0072507,GO:0098771	4.6.1.1	ko:K11005,ko:K11029	ko00230,ko05133,map00230,map05133	M00575	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02000,ko02042	1.C.11	-	-	Anthrax_toxA,DUF4214,HCBP_related,He_PIG,HemolysinCabind,RTX
CMS3_k127_3151849_1	1123228.AUIH01000054_gene3592	2.978e-82	277.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XIJU@135619|Oceanospirillales	135619|Oceanospirillales	V	(ABC) transporter	-	-	-	ko:K11004,ko:K13409	ko02010,ko03070,ko04626,ko05133,map02010,map03070,map04626,map05133	M00325,M00339,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2,3.A.1.110	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CMS3_k127_3156887_15	1210884.HG799464_gene10441	2.949e-27	114.0	COG0457@1|root,COG0457@2|Bacteria,2J0VV@203682|Planctomycetes	203682|Planctomycetes	S	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase
CMS3_k127_3156887_17	1210884.HG799464_gene10441	2.038e-05	50.0	COG0457@1|root,COG0457@2|Bacteria,2J0VV@203682|Planctomycetes	203682|Planctomycetes	S	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase
CMS3_k127_3156887_16	756272.Plabr_3124	7.825e-23	105.0	2EANR@1|root,334R8@2|Bacteria,2J30C@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3156887_3	1403819.BATR01000083_gene2434	9.474e-106	355.0	COG0577@1|root,COG0577@2|Bacteria,46UTH@74201|Verrucomicrobia,2ITTN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_3156887_2	1403819.BATR01000083_gene2433	1.196e-109	366.0	COG4591@1|root,COG4591@2|Bacteria,46UT4@74201|Verrucomicrobia,2IU3C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_3156887_6	240016.ABIZ01000001_gene1315	1.548e-87	294.0	COG1136@1|root,COG1136@2|Bacteria,46UUF@74201|Verrucomicrobia,2ITZH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_3156887_8	756272.Plabr_3125	4.894e-67	248.0	COG0845@1|root,COG0845@2|Bacteria,2IY6J@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_3156887_0	344747.PM8797T_24306	2.422e-199	641.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
CMS3_k127_3156887_1	1123371.ATXH01000022_gene959	1.243e-127	419.0	COG0436@1|root,COG0436@2|Bacteria,2GGY5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_3156887_13	869210.Marky_0290	5.771e-38	149.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS3_k127_3156887_9	247490.KSU1_B0567	3.404e-62	228.0	COG0763@1|root,COG0763@2|Bacteria,2IXXN@203682|Planctomycetes	203682|Planctomycetes	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS3_k127_3156887_5	1142394.PSMK_21340	1.158e-91	309.0	COG0052@1|root,COG0052@2|Bacteria,2IY9P@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS3_k127_3156887_10	1123508.JH636439_gene1173	9.788e-53	198.0	COG0264@1|root,COG0264@2|Bacteria,2IZGM@203682|Planctomycetes	203682|Planctomycetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS3_k127_3156887_7	648996.Theam_0089	3.315e-81	278.0	COG0528@1|root,COG0528@2|Bacteria,2G3IX@200783|Aquificae	200783|Aquificae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_3156887_11	756272.Plabr_4345	2.548e-44	168.0	COG0233@1|root,COG0233@2|Bacteria,2IYYY@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS3_k127_3156887_4	314230.DSM3645_22239	1.324e-95	322.0	COG0535@1|root,COG0535@2|Bacteria,2J0M5@203682|Planctomycetes	203682|Planctomycetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_3156887_12	1382305.AZUC01000016_gene2705	1.678e-39	159.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,26D7H@186818|Planococcaceae	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_3156887_14	530564.Psta_0132	6.293e-37	153.0	COG2088@1|root,COG2088@2|Bacteria,2IZR8@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SpoVG family	-	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
CMS3_k127_3168247_9	756272.Plabr_4636	1.161e-25	115.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,2IXHZ@203682|Planctomycetes	203682|Planctomycetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	DUF116,polyprenyl_synt
CMS3_k127_3168247_4	240016.ABIZ01000001_gene5234	1.975e-85	291.0	COG5029@1|root,COG5029@2|Bacteria,46URI@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_3168247_0	497964.CfE428DRAFT_0160	3.344e-183	591.0	COG1657@1|root,COG1657@2|Bacteria,46UEC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
CMS3_k127_3168247_1	1267535.KB906767_gene199	6.587e-135	441.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_3168247_2	1045855.DSC_08790	6.7e-133	433.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,1X4PF@135614|Xanthomonadales	135614|Xanthomonadales	I	fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_3168247_7	1121289.JHVL01000013_gene1670	9.488e-55	211.0	COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,25BFP@186801|Clostridia,36WFX@31979|Clostridiaceae	186801|Clostridia	M	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3168247_5	1183438.GKIL_0479	8.765e-80	283.0	COG0673@1|root,COG0673@2|Bacteria,1G1CZ@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_3168247_3	525904.Tter_2810	3.854e-95	325.0	COG0399@1|root,COG0399@2|Bacteria,2NNS2@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_3168247_6	1122605.KB893647_gene407	3.414e-70	243.0	COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1IVB5@117747|Sphingobacteriia	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
CMS3_k127_3168247_8	1267533.KB906733_gene3472	6.076e-39	168.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_3168247_11	755732.Fluta_1673	0.0004441	54.0	COG2911@1|root,COG3266@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,4PKFD@976|Bacteroidetes,1IKC5@117743|Flavobacteriia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CMS3_k127_3168247_10	550540.Fbal_3674	1.835e-08	55.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1SZS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_3177498_4	1142394.PSMK_27360	8.714e-31	136.0	COG1253@1|root,COG1253@2|Bacteria,2J0AW@203682|Planctomycetes	203682|Planctomycetes	S	COG1253 Hemolysins and related	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
CMS3_k127_3177498_1	237368.SCABRO_00715	1.431e-64	237.0	COG1253@1|root,COG1253@2|Bacteria,2IYEG@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_3177498_8	1382306.JNIM01000001_gene4108	2.823e-05	59.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
CMS3_k127_3177498_7	1142394.PSMK_22340	1.108e-11	74.0	COG1269@1|root,COG1269@2|Bacteria,2IZU8@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS3_k127_3177498_3	1210884.HG799468_gene13642	6.622e-32	128.0	COG2127@1|root,COG2127@2|Bacteria,2J06R@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the ClpS family	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS3_k127_3177498_0	518766.Rmar_2062	2.749e-109	373.0	COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1FJ5U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_3177498_2	215803.DB30_7213	5.621e-38	153.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,43C29@68525|delta/epsilon subdivisions,2X7CU@28221|Deltaproteobacteria,2YV3W@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3177498_5	1121346.KB899816_gene3235	3.202e-30	131.0	COG1234@1|root,COG1234@2|Bacteria,1UYM3@1239|Firmicutes,4HEWE@91061|Bacilli,26U57@186822|Paenibacillaceae	91061|Bacilli	S	beta-lactamase	rnaZ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
CMS3_k127_3177498_6	1279038.KB907344_gene3529	3.313e-13	75.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,2JPRT@204441|Rhodospirillales	204441|Rhodospirillales	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
CMS3_k127_3178565_11	521674.Plim_1714	4.611e-05	49.0	2A5UW@1|root,30UKM@2|Bacteria,2IZAT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3178565_5	1142394.PSMK_11750	2.204e-81	305.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
CMS3_k127_3178565_4	1142394.PSMK_19560	8.885e-104	364.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_3178565_6	1123242.JH636435_gene2370	2.169e-72	267.0	COG0621@1|root,COG0621@2|Bacteria,2IXJS@203682|Planctomycetes	203682|Planctomycetes	J	SMART Elongator protein 3 MiaB NifB	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS3_k127_3178565_1	530564.Psta_0519	2.487e-129	425.0	COG2189@1|root,COG2189@2|Bacteria,2IWRP@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_3178565_3	1254432.SCE1572_32230	1.363e-105	353.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,42U5B@68525|delta/epsilon subdivisions,2WQVN@28221|Deltaproteobacteria,2YWFF@29|Myxococcales	28221|Deltaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_3178565_0	414996.IL38_19300	2.636e-157	512.0	COG0471@1|root,COG0471@2|Bacteria,2GVHZ@201174|Actinobacteria,407ZE@622450|Actinopolysporales	201174|Actinobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS3_k127_3178565_7	1144275.COCOR_03147	2.936e-51	199.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,4360M@68525|delta/epsilon subdivisions,2X2HZ@28221|Deltaproteobacteria,2Z0WC@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_3178565_2	1142394.PSMK_17230	1.209e-123	416.0	COG1716@1|root,COG2203@1|root,COG4191@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWYR@203682|Planctomycetes	203682|Planctomycetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HATPase_c,Yop-YscD_cpl
CMS3_k127_3178565_8	1142394.PSMK_15660	2.988e-16	91.0	COG3147@1|root,COG3147@2|Bacteria,2IXFB@203682|Planctomycetes	203682|Planctomycetes	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3178777_4	358681.BBR47_16540	5.478e-16	87.0	COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,4HCG7@91061|Bacilli,26ZNF@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3178777_0	643867.Ftrac_3360	2.426e-56	209.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3178777_1	1234664.AMRO01000024_gene1776	4.982e-47	177.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1WEI2@129337|Geobacillus	91061|Bacilli	S	Metallo-beta-lactamase superfamily	yqgX	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_3178777_6	7227.FBpp0304622	8.074e-06	58.0	KOG1217@1|root,KOG3594@1|root,KOG4475@1|root,KOG1217@2759|Eukaryota,KOG1219@2759|Eukaryota,KOG4475@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera,45X8G@7214|Drosophilidae	33208|Metazoa	T	Worm-specific repeat type 1	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007399,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0022008,GO:0022404,GO:0030154,GO:0030182,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048468,GO:0048513,GO:0048563,GO:0048569,GO:0048666,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
CMS3_k127_3178777_3	313594.PI23P_04277	1.615e-34	150.0	COG0306@1|root,COG0306@2|Bacteria,4NFCB@976|Bacteroidetes,1HYA8@117743|Flavobacteriia,3VUZC@52959|Polaribacter	976|Bacteroidetes	U	Phosphate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	PHO4
CMS3_k127_3178777_2	1047013.AQSP01000139_gene2337	3.566e-44	169.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	CP_0066	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CMS3_k127_3178777_5	502025.Hoch_6539	2.558e-07	65.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3184312_1	234267.Acid_4124	5.143e-60	231.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
CMS3_k127_3184312_2	237368.SCABRO_01210	1.271e-17	96.0	COG4099@1|root,COG4099@2|Bacteria,2IZGJ@203682|Planctomycetes	203682|Planctomycetes	M	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Esterase,PMT_2,Peptidase_S9
CMS3_k127_3184312_0	1192034.CAP_4624	2.666e-91	309.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PVS@68525|delta/epsilon subdivisions,2WJ7B@28221|Deltaproteobacteria,2YXQQ@29|Myxococcales	28221|Deltaproteobacteria	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
CMS3_k127_3197149_0	1123278.KB893406_gene75	9.667e-277	874.0	COG1874@1|root,COG1874@2|Bacteria,4NQBQ@976|Bacteroidetes,47QIS@768503|Cytophagia	976|Bacteroidetes	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
CMS3_k127_3197149_1	1121396.KB893120_gene3067	1.032e-13	72.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3240507_0	530564.Psta_2436	4.96e-170	552.0	COG1530@1|root,COG1530@2|Bacteria,2IWSS@203682|Planctomycetes	203682|Planctomycetes	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS3_k127_3240507_1	1131269.AQVV01000003_gene707	5.453e-107	360.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	fabH1	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
CMS3_k127_3240507_2	765420.OSCT_1978	1.607e-97	330.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	dhmA	-	3.8.1.5,6.1.3.1	ko:K01563,ko:K22318,ko:K22319	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Abhydrolase_1,Abhydrolase_6
CMS3_k127_3240507_3	1122604.JONR01000003_gene1544	3.311e-20	100.0	COG3595@1|root,COG3595@2|Bacteria,1N8NB@1224|Proteobacteria,1SFVZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS3_k127_3253295_12	1124780.ANNU01000006_gene2926	1.476e-13	73.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,47S5V@768503|Cytophagia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS3_k127_3253295_8	1246484.D479_00430	8.018e-25	111.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3NE47@45667|Halobacillus	91061|Bacilli	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iYO844.BSU36850	ATP-synt_B
CMS3_k127_3253295_11	396588.Tgr7_3308	5.277e-20	97.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales	135613|Chromatiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS3_k127_3253295_1	344747.PM8797T_28844	4.886e-219	693.0	COG0056@1|root,COG0056@2|Bacteria,2IXN5@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS3_k127_3253295_3	886293.Sinac_6879	4.388e-81	279.0	COG0224@1|root,COG0224@2|Bacteria,2IXDI@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS3_k127_3253295_0	521674.Plim_0176	3.877e-231	724.0	COG0055@1|root,COG0055@2|Bacteria,2IY7P@203682|Planctomycetes	203682|Planctomycetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_3253295_14	443254.Marpi_1596	1.906e-08	63.0	COG0355@1|root,COG0355@2|Bacteria,2GDGW@200918|Thermotogae	200918|Thermotogae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS3_k127_3253295_2	1195236.CTER_4571	2.294e-95	321.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,248UU@186801|Clostridia,3WI4C@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_3253295_13	1166018.FAES_0417	1.44e-11	67.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,47T6F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
CMS3_k127_3253295_9	1444310.JANV01000115_gene4465	6.305e-21	98.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS3_k127_3253295_15	886377.Murru_2329	1.323e-07	63.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
CMS3_k127_3253295_6	1123269.NX02_00985	4.991e-61	214.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2U70V@28211|Alphaproteobacteria,2K4UN@204457|Sphingomonadales	204457|Sphingomonadales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_3253295_16	1196835.A458_02230	4.827e-06	59.0	COG0515@1|root,COG0515@2|Bacteria,1MXX9@1224|Proteobacteria,1RQFJ@1236|Gammaproteobacteria,1Z1FQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core	rfaP	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	-	ko:K02848	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF1260.b3630,iBWG_1329.BWG_3321,iEC042_1314.EC042_3937,iECDH10B_1368.ECDH10B_3812,iECDH1ME8569_1439.ECDH1ME8569_3515,iEcDH1_1363.EcDH1_0075,iJO1366.b3630,iY75_1357.Y75_RS18985	Kdo
CMS3_k127_3253295_7	240016.ABIZ01000001_gene5154	2.029e-36	158.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_3253295_5	1232437.KL662020_gene700	4.061e-70	260.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_3253295_4	356851.JOAN01000004_gene1210	1.127e-77	267.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DAQ6@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3253295_10	1280706.AUJE01000009_gene819	4.97e-20	96.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,4H256@909932|Negativicutes	909932|Negativicutes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_3257853_6	485913.Krac_6815	7.639e-68	237.0	COG0119@1|root,COG0119@2|Bacteria,2G7M0@200795|Chloroflexi	200795|Chloroflexi	E	PFAM pyruvate carboxyltransferase	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_3257853_9	1415779.JOMH01000001_gene2228	3.631e-17	88.0	COG4770@1|root,COG4770@2|Bacteria,1RJYU@1224|Proteobacteria,1S6PF@1236|Gammaproteobacteria,1X6Y8@135614|Xanthomonadales	135614|Xanthomonadales	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
CMS3_k127_3257853_4	385682.AFSL01000102_gene67	9.071e-154	502.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,2FMBN@200643|Bacteroidia,3XJ8V@558415|Marinilabiliaceae	976|Bacteroidetes	I	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS3_k127_3257853_2	880073.Calab_2517	1.258e-160	516.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_3257853_13	379066.GAU_0620	0.000179	51.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_3257853_0	525904.Tter_0977	0.0	1156.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS3_k127_3257853_5	38833.XP_003054784.1	1.626e-81	276.0	COG0529@1|root,KOG0635@2759|Eukaryota,37KPZ@33090|Viridiplantae,34GVR@3041|Chlorophyta	3041|Chlorophyta	P	Catalyzes the synthesis of activated sulfate	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS3_k127_3257853_1	118163.Ple7327_3684	2.962e-170	555.0	COG3540@1|root,COG3540@2|Bacteria,1GHE4@1117|Cyanobacteria,3VKNG@52604|Pleurocapsales	1117|Cyanobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4114,PhoD,PhoD_N
CMS3_k127_3257853_8	1054860.KB913030_gene3224	1.436e-18	96.0	COG0454@1|root,COG0454@2|Bacteria,2GMUB@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS3_k127_3257853_3	1278073.MYSTI_00649	7.429e-158	529.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YTZK@29|Myxococcales	28221|Deltaproteobacteria	CE	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
CMS3_k127_3257853_12	6500.XP_005096638.1	8.153e-08	65.0	28MII@1|root,2QU22@2759|Eukaryota,39V40@33154|Opisthokonta,3BMB6@33208|Metazoa,3CSGB@33213|Bilateria	33208|Metazoa	S	Group XIIA	PLA2G12A	GO:0003674,GO:0003824,GO:0004620,GO:0004623,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0006575,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006658,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009056,GO:0009058,GO:0009987,GO:0012505,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019637,GO:0036148,GO:0036149,GO:0036150,GO:0036151,GO:0036152,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046470,GO:0046471,GO:0046473,GO:0046474,GO:0046486,GO:0046488,GO:0047498,GO:0052689,GO:0071704,GO:0090407,GO:0097164,GO:1901564,GO:1901575,GO:1901576	3.1.1.4	ko:K01047	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,ko04014,ko04270,ko04972,ko04975,map00564,map00565,map00590,map00591,map00592,map01100,map01110,map04014,map04270,map04972,map04975	-	R01315,R01317,R02053,R07064,R07379,R07387,R07859	RC00037,RC00094	ko00000,ko00001,ko01000,ko03036	-	-	-	PLA2G12
CMS3_k127_3257853_10	1210884.HG799464_gene10943	4.649e-17	83.0	COG3293@1|root,COG3293@2|Bacteria,2IX9I@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
CMS3_k127_3257853_11	314278.NB231_08335	3.341e-08	56.0	COG3385@1|root,COG3385@2|Bacteria,1MVRM@1224|Proteobacteria,1RRFT@1236|Gammaproteobacteria,1WZIC@135613|Chromatiales	135613|Chromatiales	L	COG3385 FOG Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CMS3_k127_3257853_7	1521187.JPIM01000047_gene117	1.132e-34	133.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CMS3_k127_3275196_1	686340.Metal_0326	4.284e-103	340.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XEJF@135618|Methylococcales	135618|Methylococcales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_3275196_0	251229.Chro_4813	1.092e-302	941.0	COG1749@1|root,COG1749@2|Bacteria,1GBDW@1117|Cyanobacteria	1117|Cyanobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082
CMS3_k127_331042_2	216432.CA2559_07435	3.531e-67	235.0	COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1HY8Z@117743|Flavobacteriia	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_331042_0	479434.Sthe_2282	1.344e-127	432.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,27YTH@189775|Thermomicrobia	189775|Thermomicrobia	P	E1-E2 ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
CMS3_k127_331042_4	1444712.BN1013_01356	2.933e-16	89.0	COG1814@1|root,COG1814@2|Bacteria,2JFYP@204428|Chlamydiae	204428|Chlamydiae	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS3_k127_331042_5	243090.RB6539	8.37e-11	68.0	COG2314@1|root,COG2314@2|Bacteria,2J0G7@203682|Planctomycetes	203682|Planctomycetes	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_331042_6	522306.CAP2UW1_4074	1.149e-10	70.0	COG2331@1|root,COG2331@2|Bacteria,1PVEY@1224|Proteobacteria,2VYJG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_331042_3	886293.Sinac_5047	8.843e-47	183.0	COG0130@1|root,COG0130@2|Bacteria,2IZ94@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
CMS3_k127_331042_1	243090.RB7652	3.272e-126	411.0	COG0039@1|root,COG0039@2|Bacteria,2IY7S@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS3_k127_331042_7	344747.PM8797T_07222	0.0007191	49.0	2EUDC@1|root,33MVR@2|Bacteria,2J1GP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3312817_3	215803.DB30_8580	6.892e-79	283.0	COG1752@1|root,COG1752@2|Bacteria,1NCAA@1224|Proteobacteria,42ZIY@68525|delta/epsilon subdivisions,2WUVJ@28221|Deltaproteobacteria,2YZ3W@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS3_k127_3312817_6	32057.KB217483_gene9197	3.758e-40	165.0	COG3146@1|root,COG3146@2|Bacteria,1GHVM@1117|Cyanobacteria,1HQFA@1161|Nostocales	1117|Cyanobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_3312817_1	1267535.KB906767_gene5468	9.035e-133	437.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,KR,PP-binding,PS-DH
CMS3_k127_3312817_2	679200.HMPREF9333_01919	2.134e-93	327.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_3312817_0	1107311.Q767_10525	4.566e-158	509.0	COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,1INE4@117743|Flavobacteriia,2NZ97@237|Flavobacterium	976|Bacteroidetes	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_3312817_4	378806.STAUR_4246	3.182e-67	244.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3312817_5	110319.CF8_3037	4.719e-47	181.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,4DNIQ@85009|Propionibacteriales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3317539_5	744872.Spica_1649	1.846e-91	310.0	COG3604@1|root,COG3604@2|Bacteria,2J5TK@203691|Spirochaetes	203691|Spirochaetes	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
CMS3_k127_3317539_0	247490.KSU1_D0507	0.0	1645.0	COG2132@1|root,COG2132@2|Bacteria,2J4J4@203682|Planctomycetes	203682|Planctomycetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3317539_4	247490.KSU1_D0506	9.942e-132	445.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
CMS3_k127_3317539_3	671143.DAMO_2489	5.162e-138	454.0	COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	xpsE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_3317539_8	861299.J421_6307	8.211e-52	197.0	COG2165@1|root,COG2165@2|Bacteria,1ZTUY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_3317539_7	765910.MARPU_16535	2.802e-63	232.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WWYV@135613|Chromatiales	135613|Chromatiales	NU	Type II secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS3_k127_3317539_6	861299.J421_4404	2.018e-70	259.0	COG1450@1|root,COG1450@2|Bacteria,1ZT9Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_3317539_9	1123073.KB899241_gene3162	2.062e-21	106.0	COG3156@1|root,COG3156@2|Bacteria,1RJRE@1224|Proteobacteria,1S6CB@1236|Gammaproteobacteria,1X4D4@135614|Xanthomonadales	135614|Xanthomonadales	U	Type II secretion system protein K	xpsK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS3_k127_3317539_2	1122137.AQXF01000001_gene2749	5.181e-160	518.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2TUHT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_3317539_1	335543.Sfum_0899	2.458e-176	571.0	COG0490@1|root,COG0569@1|root,COG1226@1|root,COG0490@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria,42NKU@68525|delta/epsilon subdivisions,2WIRH@28221|Deltaproteobacteria,2MRD0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS3_k127_3317539_10	391625.PPSIR1_35712	2.936e-10	66.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_3321492_1	886293.Sinac_6466	5.708e-10	62.0	COG0537@1|root,COG0537@2|Bacteria,2IZTG@203682|Planctomycetes	203682|Planctomycetes	FG	COGs COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
CMS3_k127_3321492_0	1123508.JH636439_gene1547	2.1e-154	498.0	COG0178@1|root,COG0178@2|Bacteria,2IXFK@203682|Planctomycetes	203682|Planctomycetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_3328254_5	314230.DSM3645_08532	6.476e-40	159.0	COG1007@1|root,COG1007@2|Bacteria,2IX6J@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_3328254_4	1121920.AUAU01000011_gene149	7.716e-99	337.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08162,ko:K08226,ko:K16211	-	-	-	-	ko00000,ko02000	2.A.1.2.21,2.A.1.41,2.A.2.6	-	-	MFS_1,PUCC
CMS3_k127_3328254_0	344747.PM8797T_03660	1.807e-236	742.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS3_k127_3328254_8	204669.Acid345_4187	4.051e-16	81.0	COG3288@1|root,COG3288@2|Bacteria,3Y2S0@57723|Acidobacteria,2JM52@204432|Acidobacteriia	204432|Acidobacteriia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_3328254_3	502025.Hoch_1910	4.163e-123	402.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2YUHD@29|Myxococcales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
CMS3_k127_3328254_7	1177154.Y5S_01066	3e-29	130.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria,1XM5U@135619|Oceanospirillales	135619|Oceanospirillales	C	COG3288 NAD NADP transhydrogenase alpha subunit	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
CMS3_k127_3328254_1	575540.Isop_1124	2.238e-161	521.0	COG1282@1|root,COG1282@2|Bacteria,2IYIA@203682|Planctomycetes	203682|Planctomycetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS3_k127_3328254_6	232346.JHQL01000002_gene1139	1.172e-37	143.0	COG2329@1|root,COG2329@2|Bacteria,1MZKW@1224|Proteobacteria,1S9N8@1236|Gammaproteobacteria,1XKXM@135619|Oceanospirillales	135619|Oceanospirillales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_3328254_2	1142394.PSMK_05790	6.266e-148	481.0	COG0821@1|root,COG0821@2|Bacteria,2IXN9@203682|Planctomycetes	203682|Planctomycetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS3_k127_3331173_1	1192034.CAP_0196	3.85e-80	282.0	COG3503@1|root,COG3503@2|Bacteria,1QQ9D@1224|Proteobacteria,431ME@68525|delta/epsilon subdivisions,2WWTB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS3_k127_3331173_2	278957.ABEA03000182_gene1974	5.759e-38	152.0	COG1510@1|root,COG1510@2|Bacteria,46VGF@74201|Verrucomicrobia,3K99X@414999|Opitutae	414999|Opitutae	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3331173_0	1192034.CAP_7703	4.331e-83	299.0	2DV3U@1|root,33TXD@2|Bacteria,1NUW0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3331173_3	745718.JADT01000049_gene334	4.287e-31	141.0	COG1044@1|root,COG1044@2|Bacteria,4NSYI@976|Bacteroidetes,1I370@117743|Flavobacteriia	976|Bacteroidetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3331173_4	1032480.MLP_33800	9.082e-22	108.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
CMS3_k127_3367755_0	530564.Psta_3696	1.193e-140	467.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,zf-IS66
CMS3_k127_3367755_1	314230.DSM3645_28137	4.779e-32	129.0	COG3436@1|root,COG3436@2|Bacteria,2J11P@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
CMS3_k127_337284_0	1038860.AXAP01000107_gene4559	8.197e-98	331.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,3JW3J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	TOBE domain	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
CMS3_k127_337284_2	324925.Ppha_2269	9.215e-14	83.0	COG0644@1|root,COG0644@2|Bacteria,1FE1N@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_337284_1	1379698.RBG1_1C00001G1377	6.572e-29	132.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
CMS3_k127_3373435_0	1166948.JPZL01000001_gene2997	2.581e-80	283.0	COG1215@1|root,COG2931@1|root,COG3468@1|root,COG3693@1|root,COG1215@2|Bacteria,COG2931@2|Bacteria,COG3468@2|Bacteria,COG3693@2|Bacteria,1QV5E@1224|Proteobacteria,1T296@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MQ	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
CMS3_k127_3394147_1	314278.NB231_01898	1.058e-22	110.0	28N07@1|root,2ZB6S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3394147_2	575540.Isop_1302	7.593e-06	56.0	2DNHT@1|root,32XKG@2|Bacteria,2J0DX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3394147_0	555088.DealDRAFT_2373	1.704e-26	118.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42K3B@68298|Syntrophomonadaceae	186801|Clostridia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3394147_3	1157490.EL26_06380	0.0002051	52.0	COG1664@1|root,COG1664@2|Bacteria,1UIJB@1239|Firmicutes,4ITGM@91061|Bacilli	91061|Bacilli	M	transmembrane transcriptional regulator (anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
CMS3_k127_3427044_4	404589.Anae109_3849	4.892e-42	162.0	COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,43APW@68525|delta/epsilon subdivisions,2X63P@28221|Deltaproteobacteria,2Z38U@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_3427044_2	530564.Psta_3181	1.534e-109	367.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
CMS3_k127_3427044_5	246194.CHY_1760	1.546e-28	116.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS3_k127_3427044_0	530564.Psta_4007	1.457e-223	713.0	COG1185@1|root,COG1185@2|Bacteria,2IWXZ@203682|Planctomycetes	203682|Planctomycetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS3_k127_3427044_3	886293.Sinac_2630	6.882e-49	186.0	COG5000@1|root,COG5000@2|Bacteria,2IZCJ@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_3427044_1	575540.Isop_3482	3.377e-118	399.0	COG2204@1|root,COG2204@2|Bacteria,2IWYY@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_3460401_2	644282.Deba_2007	3.494e-116	386.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF4339
CMS3_k127_3460401_5	1123508.JH636452_gene6901	6.107e-99	329.0	COG1125@1|root,COG1125@2|Bacteria,2IX8U@203682|Planctomycetes	203682|Planctomycetes	E	COG1125 ABC-type proline glycine betaine transport systems ATPase components	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
CMS3_k127_3460401_0	237368.SCABRO_03207	2.806e-185	591.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,2IXC1@203682|Planctomycetes	203682|Planctomycetes	P	of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
CMS3_k127_3460401_4	316274.Haur_0996	1.611e-104	350.0	COG4301@1|root,COG4301@2|Bacteria,2G81E@200795|Chloroflexi	200795|Chloroflexi	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
CMS3_k127_3460401_7	648996.Theam_0893	4.085e-74	259.0	COG0294@1|root,COG0294@2|Bacteria,2G3IT@200783|Aquificae	200783|Aquificae	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS3_k127_3460401_13	1125863.JAFN01000001_gene3317	4.691e-24	104.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS3_k127_3460401_8	330214.NIDE4085	1.745e-67	258.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Cofac_haem_bdg,PDZ_2,Peptidase_M1,Peptidase_M28
CMS3_k127_3460401_3	1254432.SCE1572_15770	7.714e-113	380.0	2CF5E@1|root,2ZFJ4@2|Bacteria,1Q1S5@1224|Proteobacteria,437FB@68525|delta/epsilon subdivisions,2X2MW@28221|Deltaproteobacteria,2YTW7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3460401_17	1280941.HY2_07315	9.817e-06	54.0	COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,2U9BM@28211|Alphaproteobacteria,43YGG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	MA20_36950	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_3460401_15	886293.Sinac_2241	8.101e-08	65.0	COG0795@1|root,COG0795@2|Bacteria,2IZJF@203682|Planctomycetes	203682|Planctomycetes	S	Permease YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS3_k127_3460401_20	351016.RAZWK3B_06402	0.0008004	51.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria,2P21D@2433|Roseobacter	28211|Alphaproteobacteria	S	permeases	MA20_28210	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS3_k127_3460401_12	1411123.JQNH01000001_gene1175	1.255e-46	183.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2TXAA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_3460401_14	321332.CYB_2148	4.247e-15	82.0	COG3216@1|root,COG3216@2|Bacteria,1G7YZ@1117|Cyanobacteria,1H15V@1129|Synechococcus	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
CMS3_k127_3460401_9	671143.DAMO_1640	4.543e-66	242.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02841,ko:K02843,ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_3460401_11	706587.Desti_1430	9.356e-51	190.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2WQ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CMS3_k127_3460401_10	1229203.KI301992_gene1310	3.871e-55	202.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria,3UX8A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
CMS3_k127_3460401_1	1304883.KI912532_gene568	8.104e-164	539.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria,2KVQ3@206389|Rhodocyclales	206389|Rhodocyclales	J	COG0480 Translation elongation factors (GTPases)	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
CMS3_k127_3460401_18	1033743.CAES01000015_gene2234	2.718e-05	55.0	COG1595@1|root,COG1595@2|Bacteria,1U40C@1239|Firmicutes,4HCU0@91061|Bacilli,26S2C@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW11	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3460401_6	439235.Dalk_2414	2.793e-96	328.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2MIUY@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_3460401_19	983917.RGE_11890	0.0004414	48.0	2BY35@1|root,34C6I@2|Bacteria,1PABX@1224|Proteobacteria,2W6KC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3460401_16	349521.HCH_01325	1.216e-06	50.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,1S32B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CMS3_k127_3462348_0	886293.Sinac_5211	2.961e-44	165.0	COG3293@1|root,COG3293@2|Bacteria,2J0XQ@203682|Planctomycetes	203682|Planctomycetes	L	COGs COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
CMS3_k127_3462348_1	561229.Dd1591_0214	4.859e-42	161.0	COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,1RSHY@1236|Gammaproteobacteria,2JF4A@204037|Dickeya	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CMS3_k127_3462348_2	1267534.KB906759_gene1988	1.535e-34	145.0	COG3391@1|root,COG3391@2|Bacteria,3Y648@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_355876_0	551275.KB899544_gene1472	9.791e-97	338.0	28M2S@1|root,2ZAH5@2|Bacteria,1MVH5@1224|Proteobacteria,2V6CQ@28211|Alphaproteobacteria,43WPI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_356555_1	1278073.MYSTI_01766	1.036e-100	355.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_356555_0	861299.J421_5836	9.317e-117	404.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_5836|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_356555_6	864051.BurJ1DRAFT_3406	6.803e-07	55.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,2VTQN@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase (SDR)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_356555_2	861299.J421_1666	5.618e-92	334.0	COG0515@1|root,COG0515@2|Bacteria,1ZUM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_356555_4	240292.Ava_3644	1.605e-36	151.0	COG1462@1|root,COG1462@2|Bacteria,1G2XT@1117|Cyanobacteria,1HPMP@1161|Nostocales	1117|Cyanobacteria	M	PFAM Curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
CMS3_k127_356555_5	56110.Oscil6304_4546	1.772e-30	126.0	2E3WH@1|root,32YTP@2|Bacteria,1G72D@1117|Cyanobacteria,1HFKM@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_356555_3	748247.AZKH_p0450	6.411e-53	196.0	COG0705@1|root,COG0705@2|Bacteria,1RJYI@1224|Proteobacteria,2W1AJ@28216|Betaproteobacteria,2KXTX@206389|Rhodocyclales	206389|Rhodocyclales	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_3592590_12	1034943.BN1094_03449	2.572e-05	59.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1JD7V@118969|Legionellales	118969|Legionellales	NU	Bacterial type II and III secretion system protein	lspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	SPOR,Secretin,Secretin_N
CMS3_k127_3592590_2	1123242.JH636434_gene3727	7.051e-75	288.0	COG1450@1|root,COG1450@2|Bacteria,2IX4B@203682|Planctomycetes	203682|Planctomycetes	NU	general secretion pathway protein D	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_3592590_4	314230.DSM3645_20637	3.758e-38	155.0	COG0589@1|root,COG0589@2|Bacteria,2J11D@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3592590_9	72019.SARC_11747T0	4.461e-14	86.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta	33154|Opisthokonta	T	calcium ion binding	-	-	-	ko:K02599	ko01522,ko04320,ko04330,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002	-	-	-	EGF,SRCR,hEGF
CMS3_k127_3592590_10	1009370.ALO_10184	7.147e-12	77.0	2DP2M@1|root,3309H@2|Bacteria,1V5H4@1239|Firmicutes,4H4EY@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3592590_3	1262914.BN533_01539	1.422e-62	218.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4H3ZR@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS3_k127_3592590_6	335543.Sfum_1382	7.121e-22	100.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2MRZ8@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS3_k127_3592590_1	1142394.PSMK_00390	2.438e-96	323.0	COG0552@1|root,COG0552@2|Bacteria,2IXAG@203682|Planctomycetes	203682|Planctomycetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS3_k127_3592590_0	635013.TherJR_1005	4.722e-164	559.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,260SC@186807|Peptococcaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
CMS3_k127_3592590_5	886293.Sinac_7513	1.634e-28	126.0	COG2267@1|root,COG2267@2|Bacteria,2J0RW@203682|Planctomycetes	203682|Planctomycetes	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3592590_8	1229487.AMYW01000054_gene3452	3.496e-15	86.0	COG3350@1|root,COG3350@2|Bacteria,4NRFU@976|Bacteroidetes,1I3FC@117743|Flavobacteriia,2NWJX@237|Flavobacterium	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CMS3_k127_3592590_7	1136163.M565_ctg5P1486	4.043e-17	92.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1S7V6@1236|Gammaproteobacteria,1XX6S@135623|Vibrionales	135623|Vibrionales	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3592590_11	379731.PST_2293	3.844e-09	68.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1Z2HM@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	D	cell division protein FtsK	ftsK	GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_3598001_0	391589.RGAI101_3938	7.918e-84	289.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1R4VS@1224|Proteobacteria,2U0SN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3598001_3	335659.S23_30980	3.366e-47	177.0	2CDHC@1|root,30KXA@2|Bacteria,1PT2N@1224|Proteobacteria,2UANN@28211|Alphaproteobacteria,3K6B4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3598001_1	716928.AJQT01000028_gene2339	4.8e-76	261.0	COG5588@1|root,COG5588@2|Bacteria,1PZHC@1224|Proteobacteria,2TVVV@28211|Alphaproteobacteria,4BBPN@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS3_k127_3598001_2	1318628.MARLIPOL_15954	3.35e-52	194.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,1RSE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
CMS3_k127_3610605_2	1254432.SCE1572_04870	0.0003077	52.0	29X8Q@1|root,30IY3@2|Bacteria,1QZTR@1224|Proteobacteria,43CNP@68525|delta/epsilon subdivisions,2X7VZ@28221|Deltaproteobacteria,2YYEQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3610605_1	1340493.JNIF01000003_gene3955	2.455e-41	156.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
CMS3_k127_3610605_0	478741.JAFS01000002_gene875	1.928e-41	160.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_3625928_8	1380390.JIAT01000010_gene3433	6.068e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,2IEEE@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3625928_1	886293.Sinac_6154	1.912e-247	793.0	COG2866@1|root,COG2866@2|Bacteria,2IXPH@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_3625928_3	1185876.BN8_04008	1.314e-68	239.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,47KJ2@768503|Cytophagia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_3625928_7	314230.DSM3645_11122	2.631e-29	121.0	COG1917@1|root,COG1917@2|Bacteria,2J1N5@203682|Planctomycetes	203682|Planctomycetes	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3625928_5	886293.Sinac_2589	2.68e-52	188.0	COG0105@1|root,COG0105@2|Bacteria,2IZQ6@203682|Planctomycetes	203682|Planctomycetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS3_k127_3625928_6	1499967.BAYZ01000014_gene6411	6.78e-33	140.0	COG0407@1|root,COG0407@2|Bacteria,2NPIC@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS3_k127_3625928_4	344747.PM8797T_01824	6.513e-66	253.0	COG0793@1|root,COG0793@2|Bacteria,2IX9Q@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_3625928_0	562970.Btus_2178	0.0	1028.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,2781C@186823|Alicyclobacillaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_3625928_9	743722.Sph21_4786	6.117e-07	58.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1IU4C@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
CMS3_k127_3625928_2	314230.DSM3645_23726	4.958e-145	472.0	COG1055@1|root,COG1055@2|Bacteria,2IY4X@203682|Planctomycetes	203682|Planctomycetes	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
CMS3_k127_3658541_0	498761.HM1_2508	5.851e-87	295.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS3_k127_3658541_7	1121405.dsmv_1158	1.555e-26	121.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_3658541_4	926554.KI912680_gene858	6.388e-40	152.0	COG0662@1|root,COG0662@2|Bacteria,1WMY9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_3658541_8	886293.Sinac_2582	2.112e-15	90.0	2CGC8@1|root,32S3M@2|Bacteria,2J0H4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3658541_10	720555.BATR1942_11090	3.946e-13	81.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus	91061|Bacilli	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS3_k127_3658541_13	42345.XP_008808822.1	7.442e-06	58.0	COG3914@1|root,KOG4626@2759|Eukaryota,37IV9@33090|Viridiplantae,3G9DX@35493|Streptophyta,3KPD8@4447|Liliopsida	35493|Streptophyta	GOT	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY	SPY	GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_16,TPR_7,TPR_8
CMS3_k127_3658541_9	530564.Psta_2852	3.726e-14	85.0	COG3170@1|root,COG3170@2|Bacteria,2IZEW@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3658541_6	237368.SCABRO_00698	5.4e-33	133.0	COG0764@1|root,COG0764@2|Bacteria,2IZNA@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS3_k127_3658541_12	645127.ckrop_0128	2.77e-07	63.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,22M4R@1653|Corynebacteriaceae	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
CMS3_k127_3658541_5	497965.Cyan7822_3744	4.672e-38	157.0	COG0496@1|root,COG0496@2|Bacteria,1G30G@1117|Cyanobacteria,3KH0G@43988|Cyanothece	1117|Cyanobacteria	S	TIGRFAM stationary-phase survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS3_k127_3658541_3	1443665.JACA01000003_gene613	3.141e-73	266.0	COG0596@1|root,COG0596@2|Bacteria,4NQYB@976|Bacteroidetes,1I318@117743|Flavobacteriia,2YK2Q@290174|Aquimarina	976|Bacteroidetes	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_3658541_2	886293.Sinac_6081	1.86e-73	269.0	28M0D@1|root,2ZAFE@2|Bacteria,2IX4T@203682|Planctomycetes	203682|Planctomycetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
CMS3_k127_3658541_1	1379270.AUXF01000004_gene3068	2.381e-78	269.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3658541_14	575540.Isop_0193	0.0001354	53.0	2BZ1M@1|root,34AZS@2|Bacteria,2J3U6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3666215_5	269799.Gmet_0065	3.872e-120	398.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WJ1M@28221|Deltaproteobacteria,43S7W@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls-2	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS3_k127_3666215_1	485913.Krac_7237	4.307e-179	571.0	COG1262@1|root,COG1262@2|Bacteria,2G89M@200795|Chloroflexi	200795|Chloroflexi	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS3_k127_3666215_6	1122176.KB903598_gene4683	2.29e-119	398.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes	976|Bacteroidetes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS3_k127_3666215_15	1249997.JHZW01000002_gene1673	1.266e-74	261.0	COG0500@1|root,COG2226@2|Bacteria,4PJ70@976|Bacteroidetes,1IETH@117743|Flavobacteriia,2PIUK@252356|Maribacter	976|Bacteroidetes	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS3_k127_3666215_29	861299.J421_3057	0.0006367	53.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
CMS3_k127_3666215_8	1499967.BAYZ01000009_gene5378	2.004e-111	368.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS3_k127_3666215_7	1026882.MAMP_02634	2.665e-116	403.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,460Y9@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS3_k127_3666215_4	391009.Tmel_1010	3.6e-135	441.0	COG1509@1|root,COG1509@2|Bacteria,2GC9P@200918|Thermotogae	200918|Thermotogae	C	Lysine 2,3-aminomutase YodO family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_3666215_27	1122611.KB903940_gene1843	4.996e-07	64.0	COG2234@1|root,COG2234@2|Bacteria,2GIT0@201174|Actinobacteria,4EFVR@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase family M28	-	-	3.4.11.24	ko:K19702	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M28
CMS3_k127_3666215_11	1379698.RBG1_1C00001G1527	4.835e-100	362.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,fn3
CMS3_k127_3666215_12	1379698.RBG1_1C00001G0173	5.677e-99	359.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,fn3
CMS3_k127_3666215_23	1441629.PCH70_19980	4.669e-15	87.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1Z4X1@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS3_k127_3666215_28	886293.Sinac_0089	3.942e-06	55.0	COG0501@1|root,COG0501@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_3666215_3	247490.KSU1_B0239	1.662e-141	462.0	COG1160@1|root,COG1160@2|Bacteria,2IWXY@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS3_k127_3666215_18	1449126.JQKL01000011_gene3561	3.082e-61	228.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,269PS@186813|unclassified Clostridiales	186801|Clostridia	S	Conserved hypothetical protein 698	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
CMS3_k127_3666215_21	1395587.P364_0127850	4.364e-26	121.0	COG3153@1|root,COG3153@2|Bacteria,1VR76@1239|Firmicutes,4ISHH@91061|Bacilli,276ZW@186822|Paenibacillaceae	91061|Bacilli	S	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS3_k127_3666215_13	1123278.KB893387_gene4430	8.861e-94	342.0	COG1577@1|root,COG1874@1|root,COG3391@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG3391@2|Bacteria,4PPRK@976|Bacteroidetes,47TYG@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3666215_24	483219.LILAB_00175	4.989e-13	81.0	COG3391@1|root,COG3391@2|Bacteria,1Q9YK@1224|Proteobacteria,434PS@68525|delta/epsilon subdivisions,2WZ10@28221|Deltaproteobacteria,2Z137@29|Myxococcales	28221|Deltaproteobacteria	S	Low-density lipoprotein-receptor YWTD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
CMS3_k127_3666215_2	344747.PM8797T_10689	3.599e-152	495.0	COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes	203682|Planctomycetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
CMS3_k127_3666215_25	1242864.D187_010508	2.299e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2YVS5@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
CMS3_k127_3666215_10	1142394.PSMK_14360	7.488e-104	361.0	COG4796@1|root,COG4796@2|Bacteria,2IY1C@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the GSP D family	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin
CMS3_k127_3666215_22	886293.Sinac_3795	6.512e-26	124.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_3666215_16	886293.Sinac_5296	2.293e-72	269.0	COG0793@1|root,COG0793@2|Bacteria,2IX9Q@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_3666215_19	886293.Sinac_3714	2.138e-40	154.0	COG0727@1|root,COG0727@2|Bacteria,2IZM1@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS3_k127_3666215_9	1123242.JH636434_gene3170	9.243e-105	362.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PDZ_2,Peptidase_M28
CMS3_k127_3666215_20	886293.Sinac_7067	1.864e-30	125.0	COG0824@1|root,COG0824@2|Bacteria,2J0BH@203682|Planctomycetes	203682|Planctomycetes	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_3666215_0	986075.CathTA2_2058	9.066e-226	710.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli	91061|Bacilli	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09060,iYO844.BSU30560	PEPCK_ATP
CMS3_k127_3666215_26	314230.DSM3645_05924	5.48e-08	59.0	COG2198@1|root,COG2198@2|Bacteria,2J1FC@203682|Planctomycetes	203682|Planctomycetes	T	(Hpt) domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
CMS3_k127_3666215_14	645991.Sgly_1057	8.366e-86	299.0	COG0272@1|root,COG0847@1|root,COG0272@2|Bacteria,COG0847@2|Bacteria,1V0A6@1239|Firmicutes,24KGX@186801|Clostridia,265GN@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM exonuclease, DNA polymerase III, epsilon subunit family	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS3_k127_3666215_17	521674.Plim_2844	2.525e-68	249.0	COG0272@1|root,COG0272@2|Bacteria,2IXIC@203682|Planctomycetes	203682|Planctomycetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS3_k127_367883_0	945713.IALB_0283	0.0	1266.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CMS3_k127_3712976_3	1232683.ADIMK_1382	6.705e-66	228.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,464PE@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.71	ko:K00128,ko:K06447	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_3712976_10	1232410.KI421424_gene1807	2.199e-19	92.0	2BWVJ@1|root,33YN1@2|Bacteria,1NXTC@1224|Proteobacteria,430BZ@68525|delta/epsilon subdivisions,2WVZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3712976_4	1196029.ALIM01000037_gene1106	3.484e-58	220.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmCD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS3_k127_3712976_1	886293.Sinac_5975	4.726e-100	335.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_3712976_8	1121428.DESHY_60285___1	2.601e-29	125.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,262QN@186807|Peptococcaceae	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS3_k127_3712976_0	1142394.PSMK_01740	8.344e-144	464.0	COG0468@1|root,COG0468@2|Bacteria,2IX4U@203682|Planctomycetes	203682|Planctomycetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS3_k127_3712976_5	1254432.SCE1572_38840	2.034e-46	184.0	COG0438@1|root,COG0438@2|Bacteria,1R0NE@1224|Proteobacteria,42TFU@68525|delta/epsilon subdivisions,2X879@28221|Deltaproteobacteria,2Z1TP@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3712976_12	1121468.AUBR01000041_gene1696	6.93e-13	77.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,24MQT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CMS3_k127_3712976_7	1142394.PSMK_16420	5.731e-41	153.0	COG0234@1|root,COG0234@2|Bacteria,2IZTF@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_3712976_2	479434.Sthe_1382	1.865e-69	244.0	COG0434@1|root,COG0434@2|Bacteria,2G6UF@200795|Chloroflexi,27Y89@189775|Thermomicrobia	189775|Thermomicrobia	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
CMS3_k127_3712976_9	216142.LT40_19160	1.091e-20	105.0	COG1619@1|root,COG1619@2|Bacteria,1RDGY@1224|Proteobacteria,1T05T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	peptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
CMS3_k127_3712976_6	234267.Acid_0813	2.409e-44	175.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria	57723|Acidobacteria	E	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_3712976_14	762982.HMPREF9442_02729	0.0002845	49.0	COG2378@1|root,COG2378@2|Bacteria,4NN6R@976|Bacteroidetes,2FS46@200643|Bacteroidia	976|Bacteroidetes	K	HTH domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS3_k127_3712976_13	1209072.ALBT01000072_gene36	0.0002346	53.0	COG1501@1|root,COG2931@1|root,COG1501@2|Bacteria,COG2931@2|Bacteria,1PPUE@1224|Proteobacteria,1RQKW@1236|Gammaproteobacteria,1FHX1@10|Cellvibrio	1236|Gammaproteobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Laminin_G_3
CMS3_k127_3717828_0	502025.Hoch_2654	1.11e-139	461.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,437G6@68525|delta/epsilon subdivisions,2X2NS@28221|Deltaproteobacteria,2YU1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_3723309_2	882082.SaccyDRAFT_4151	1.325e-05	57.0	COG1178@1|root,COG1178@2|Bacteria,2GKDH@201174|Actinobacteria,4DY72@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type Fe3 transport system, permease component	thiP	-	-	ko:K02011,ko:K02063	ko02010,map02010	M00190,M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10,3.A.1.19	-	-	BPD_transp_1
CMS3_k127_3723309_0	765912.Thimo_1760	4.009e-64	233.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1WWM0@135613|Chromatiales	135613|Chromatiales	P	extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
CMS3_k127_3723309_1	1396418.BATQ01000129_gene4818	3.124e-34	148.0	COG1109@1|root,COG1109@2|Bacteria,46SB1@74201|Verrucomicrobia,2ITGG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_3728899_3	886293.Sinac_0255	1.192e-55	199.0	COG4219@1|root,COG4932@1|root,COG4219@2|Bacteria,COG4932@2|Bacteria,2IZ9V@203682|Planctomycetes	203682|Planctomycetes	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS3_k127_3728899_0	886293.Sinac_0920	2.783e-147	480.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_3728899_1	1210884.HG799462_gene8057	9.425e-69	254.0	2B9HV@1|root,322W0@2|Bacteria,2IZR4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3728899_2	1123242.JH636437_gene6107	1.225e-60	212.0	COG0480@1|root,COG0480@2|Bacteria,2IX5V@203682|Planctomycetes	203682|Planctomycetes	J	COG0480 Translation elongation factors	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_378161_0	319003.Bra1253DRAFT_07187	6.531e-211	672.0	COG1404@1|root,COG1404@2|Bacteria,1R5Y1@1224|Proteobacteria,2U1X6@28211|Alphaproteobacteria,3K1XU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_3782579_2	595537.Varpa_1002	6.041e-19	87.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2VTR4@28216|Betaproteobacteria,4AEDJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
CMS3_k127_3782579_0	316274.Haur_2192	1.052e-54	210.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_3782579_1	518766.Rmar_2430	1.448e-25	111.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes	976|Bacteroidetes	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_3792612_1	1122612.AUBA01000018_gene2684	0.0004736	42.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,2KEB3@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_3792612_0	324602.Caur_0299	5.389e-10	71.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_3796455_2	525257.HMPREF0204_11199	4.184e-33	138.0	COG1285@1|root,COG1285@2|Bacteria,4NN0A@976|Bacteroidetes,1I5ZJ@117743|Flavobacteriia,3ZP6D@59732|Chryseobacterium	976|Bacteroidetes	S	Magnesium transporter MgtC	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_3796455_0	1379698.RBG1_1C00001G1527	2.398e-113	393.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,fn3
CMS3_k127_3796455_3	1122179.KB890451_gene4532	4.726e-21	109.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,He_PIG,Laminin_G_3,VCBS
CMS3_k127_3796455_1	1313304.CALK_0748	3.005e-97	346.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	msbA	-	-	ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_3796455_4	1218084.BBJK01000030_gene2873	0.0004561	52.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2VK05@28216|Betaproteobacteria,1K33H@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glycos_transf_1
CMS3_k127_3807069_1	1322246.BN4_12750	1.163e-170	569.0	COG1042@1|root,COG1042@2|Bacteria,1NU6B@1224|Proteobacteria,42NAU@68525|delta/epsilon subdivisions,2WJHX@28221|Deltaproteobacteria,2M8HI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS3_k127_3807069_5	1499967.BAYZ01000013_gene6442	1.225e-51	209.0	COG1014@1|root,COG1014@2|Bacteria,2NPBG@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB	-	1.2.7.8	ko:K00179,ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
CMS3_k127_3807069_0	1047013.AQSP01000098_gene2570	8.338e-181	584.0	COG4231@1|root,COG4231@2|Bacteria,2NP25@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179,ko:K08941	-	M00598	-	-	br01601,ko00000,ko00002,ko00194,ko01000	-	-	-	POR_N,TPP_enzyme_C
CMS3_k127_3807069_2	234267.Acid_3219	1.081e-102	371.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3807069_6	1131269.AQVV01000032_gene304	5.344e-27	113.0	2DCXT@1|root,2ZFR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3807069_4	665571.STHERM_c03630	4.789e-76	257.0	COG0432@1|root,COG0432@2|Bacteria,2J7PN@203691|Spirochaetes	203691|Spirochaetes	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_3807069_3	886293.Sinac_6244	2.25e-101	345.0	COG0075@1|root,COG0075@2|Bacteria,2IXFP@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_3807069_7	1210884.HG799465_gene11644	2.933e-05	56.0	2EQDK@1|root,33HZN@2|Bacteria,2J1FY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3823185_0	234267.Acid_5749	2.691e-151	512.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_3823185_1	1254432.SCE1572_34585	4.818e-107	357.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	tnp3510a	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS3_k127_3824966_1	324602.Caur_0299	6.135e-20	101.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_3834440_4	1038860.AXAP01000157_gene8657	3.627e-20	96.0	COG2801@1|root,COG2801@2|Bacteria,1MX69@1224|Proteobacteria,2TSIE@28211|Alphaproteobacteria,3K2DN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
CMS3_k127_3834440_3	1185876.BN8_02868	2.945e-40	171.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3834440_5	45351.EDO45037	4.642e-18	96.0	KOG3714@1|root,KOG3714@2759|Eukaryota,3AMRH@33154|Opisthokonta,3C0S4@33208|Metazoa	33208|Metazoa	O	It is involved in the biological process described with	-	GO:0006810,GO:0006897,GO:0006909,GO:0008150,GO:0016192,GO:0051179,GO:0051234,GO:0098657	-	-	-	-	-	-	-	-	-	-	Astacin,ShK
CMS3_k127_3834440_0	156889.Mmc1_2548	2.418e-114	378.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS3_k127_3834440_6	1089553.Tph_c04050	7.896e-06	51.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,42IC3@68295|Thermoanaerobacterales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_3834440_1	886293.Sinac_1993	9.837e-52	187.0	COG5609@1|root,COG5609@2|Bacteria,2J0WE@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
CMS3_k127_3834440_2	886293.Sinac_1999	4.953e-46	169.0	COG5609@1|root,COG5609@2|Bacteria,2J0KX@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
CMS3_k127_3845652_1	273068.TTE0531	1.88e-34	139.0	COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,249V9@186801|Clostridia,42HYN@68295|Thermoanaerobacterales	186801|Clostridia	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
CMS3_k127_3845652_0	555079.Toce_2001	7.537e-196	619.0	COG2403@1|root,COG2403@2|Bacteria,1TPZD@1239|Firmicutes,24E2D@186801|Clostridia,42HSE@68295|Thermoanaerobacterales	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
CMS3_k127_3848236_14	502025.Hoch_2677	1.528e-11	75.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_3848236_1	1142394.PSMK_07170	3.157e-121	419.0	COG4775@1|root,COG4775@2|Bacteria,2IWWA@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_3848236_0	247490.KSU1_B0551	2.203e-122	409.0	COG0305@1|root,COG0305@2|Bacteria,2IXJT@203682|Planctomycetes	203682|Planctomycetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS3_k127_3848236_10	1191523.MROS_1863	3.846e-25	111.0	COG0359@1|root,COG0359@2|Bacteria	2|Bacteria	J	rRNA binding	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS3_k127_3848236_8	1142394.PSMK_16170	1.517e-34	138.0	COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes	203682|Planctomycetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS3_k127_3848236_12	575540.Isop_2891	1.374e-16	85.0	COG0360@1|root,COG0360@2|Bacteria,2J0U0@203682|Planctomycetes	203682|Planctomycetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS3_k127_3848236_5	1297742.A176_02062	7.128e-51	186.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2WPHH@28221|Deltaproteobacteria,2YZP7@29|Myxococcales	28221|Deltaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS3_k127_3848236_7	1123508.JH636445_gene6804	5.091e-37	147.0	COG1825@1|root,COG1825@2|Bacteria,2J050@203682|Planctomycetes	203682|Planctomycetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS3_k127_3848236_2	247490.KSU1_B0544	2.569e-104	354.0	COG0462@1|root,COG0462@2|Bacteria,2IXI0@203682|Planctomycetes	203682|Planctomycetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS3_k127_3848236_4	575540.Isop_3095	7.161e-82	283.0	COG1207@1|root,COG1207@2|Bacteria,2IXXB@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
CMS3_k127_3848236_15	1313304.CALK_1252	4.133e-10	73.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
CMS3_k127_3848236_6	1210884.HG799467_gene13293	3.658e-42	159.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_3848236_11	530564.Psta_0921	5.257e-22	104.0	COG1734@1|root,COG1734@2|Bacteria,2J04D@203682|Planctomycetes	203682|Planctomycetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS3_k127_3848236_13	1142394.PSMK_25120	2.778e-16	88.0	COG0597@1|root,COG0597@2|Bacteria,2J0RI@203682|Planctomycetes	203682|Planctomycetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_3848236_3	264732.Moth_0915	5.818e-93	317.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS3_k127_3848236_17	1030157.AFMP01000011_gene3698	0.0003975	52.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,2K04M@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_8
CMS3_k127_3848236_9	509191.AEDB02000086_gene2771	1.27e-29	127.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,3WHRZ@541000|Ruminococcaceae	186801|Clostridia	E	histidinol phosphate phosphatase HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
CMS3_k127_3853471_11	1123060.JONP01000020_gene3185	1.436e-21	100.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TVFK@28211|Alphaproteobacteria,2JQTA@204441|Rhodospirillales	204441|Rhodospirillales	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
CMS3_k127_3853471_15	42256.RradSPS_0743	3.471e-13	82.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_3853471_5	1382306.JNIM01000001_gene1984	7.545e-54	196.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2,Peptidase_M22
CMS3_k127_3853471_4	713586.KB900536_gene1763	6.078e-59	220.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WX0Q@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
CMS3_k127_3853471_12	1123508.JH636442_gene3861	2.207e-21	96.0	COG1393@1|root,COG1393@2|Bacteria,2J19I@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3853471_3	1267535.KB906767_gene1464	4.663e-77	266.0	COG0602@1|root,COG0602@2|Bacteria,3Y2UA@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_3853471_16	926569.ANT_03060	8.036e-11	68.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3853471_7	1142394.PSMK_08290	1.179e-41	170.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	yeaP	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF,GAF_2,GAF_3,GGDEF
CMS3_k127_3853471_2	706587.Desti_0614	7.808e-92	326.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,42RE9@68525|delta/epsilon subdivisions,2WNSX@28221|Deltaproteobacteria,2MQZV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
CMS3_k127_3853471_6	1142394.PSMK_29780	2.514e-44	174.0	COG0515@1|root,COG0515@2|Bacteria,2IZHV@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_3853471_9	1283300.ATXB01000002_gene2568	5.248e-25	114.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria,1XFSP@135618|Methylococcales	135618|Methylococcales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_3853471_0	243090.RB6932	1.092e-127	415.0	COG0031@1|root,COG0031@2|Bacteria,2IXCX@203682|Planctomycetes	203682|Planctomycetes	E	cysteine synthase	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3853471_13	1230460.C495_08795	1.331e-20	98.0	COG1310@1|root,arCOG01138@2157|Archaea,2XXA9@28890|Euryarchaeota,23VWD@183963|Halobacteria	183963|Halobacteria	S	metal-dependent protease of the PAD1 JAB1 superfamily	jamm1	-	3.4.19.15	ko:K20110	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Prok-JAB
CMS3_k127_3853471_1	575540.Isop_1376	4.627e-125	409.0	COG0476@1|root,COG0476@2|Bacteria,2IWVB@203682|Planctomycetes	203682|Planctomycetes	H	involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS3_k127_3853471_8	521674.Plim_3642	1.376e-38	153.0	COG1943@1|root,COG1943@2|Bacteria,2J16A@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_3883679_5	425104.Ssed_2005	3.901e-93	319.0	COG3104@1|root,COG3104@2|Bacteria,1R5E8@1224|Proteobacteria,1RQR0@1236|Gammaproteobacteria,2QA3H@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_3883679_21	1142394.PSMK_21480	5.2e-12	77.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_3883679_2	1142394.PSMK_23630	5.451e-174	593.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2IYCQ@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
CMS3_k127_3883679_19	886293.Sinac_1911	1.612e-16	87.0	2B8BF@1|root,321K5@2|Bacteria,2IZTE@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF2617	-	-	-	-	-	-	-	-	-	-	-	-	DUF2617
CMS3_k127_3883679_15	1499967.BAYZ01000068_gene1969	4.506e-29	129.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_3883679_20	237368.SCABRO_03851	2.314e-16	91.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_3883679_18	222534.KB893727_gene5405	2.277e-18	91.0	COG0494@1|root,COG0494@2|Bacteria,2I56M@201174|Actinobacteria	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_3883679_11	661478.OP10G_2260	1.31e-38	147.0	COG0780@1|root,COG0780@2|Bacteria	2|Bacteria	G	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS3_k127_3883679_6	292459.STH1821	2.077e-84	290.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_3883679_16	349124.Hhal_0540	7.556e-22	101.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X1A7@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_3883679_13	1142394.PSMK_03230	1.973e-36	144.0	COG0316@1|root,COG0316@2|Bacteria,2J01F@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS3_k127_3883679_0	251221.35211934	1.335e-268	833.0	COG0719@1|root,COG0719@2|Bacteria,1G0TH@1117|Cyanobacteria	1117|Cyanobacteria	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS3_k127_3883679_10	497964.CfE428DRAFT_0261	3.864e-48	178.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_3883679_4	1382359.JIAL01000001_gene679	8.572e-118	383.0	COG0396@1|root,COG0396@2|Bacteria,3Y3S4@57723|Acidobacteria	57723|Acidobacteria	O	ABC transporter	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS3_k127_3883679_3	671143.DAMO_2381	1.476e-118	397.0	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
CMS3_k127_3883679_1	1042209.HK44_007330	1.572e-177	569.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1YMXS@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Cysteine desulfurase	sufS	-	2.8.1.7,4.4.1.16	ko:K01766,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
CMS3_k127_3883679_8	472759.Nhal_0692	9.71e-59	207.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1WW3I@135613|Chromatiales	135613|Chromatiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
CMS3_k127_3883679_14	754476.Q7A_1539	1.386e-31	133.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S8YV@1236|Gammaproteobacteria,463JX@72273|Thiotrichales	72273|Thiotrichales	S	PaaD-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS3_k127_3883679_12	1110502.TMO_0110	9.906e-37	143.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2JT8V@204441|Rhodospirillales	204441|Rhodospirillales	S	Iron-sulfur cluster assembly protein	sufT	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS3_k127_3883679_7	479434.Sthe_1150	3.035e-59	213.0	COG0223@1|root,COG0223@2|Bacteria	2|Bacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	GO:0003674,GO:0003824,GO:0004479,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044419,GO:0046483,GO:0046983,GO:0051704,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
CMS3_k127_3883679_9	1035308.AQYY01000001_gene1510	4.116e-49	182.0	COG0110@1|root,COG0110@2|Bacteria,1TT21@1239|Firmicutes,24CCH@186801|Clostridia,2616C@186807|Peptococcaceae	186801|Clostridia	M	PFAM Bacterial transferase hexapeptide (three repeats)	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
CMS3_k127_388500_4	314230.DSM3645_20627	1.656e-46	172.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_388500_6	335543.Sfum_3099	1.39e-24	111.0	2E69N@1|root,330XJ@2|Bacteria,1NM8X@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_388500_2	1121406.JAEX01000002_gene899	5.609e-79	301.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43BN0@68525|delta/epsilon subdivisions,2X702@28221|Deltaproteobacteria,2MH9Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
CMS3_k127_388500_5	1210884.HG799464_gene10459	2.726e-42	168.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,CBAH
CMS3_k127_388500_0	472759.Nhal_3600	3.78e-178	600.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1WXKG@135613|Chromatiales	135613|Chromatiales	DM	mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM,MscS_porin
CMS3_k127_388500_3	751944.HALDL1_02915	2.95e-50	192.0	COG0598@1|root,arCOG02265@2157|Archaea,2XTRP@28890|Euryarchaeota,23TNC@183963|Halobacteria	183963|Halobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_388500_1	765952.PUV_00830	8.248e-113	375.0	COG0861@1|root,COG0861@2|Bacteria,2JGY6@204428|Chlamydiae	204428|Chlamydiae	P	Integral membrane protein TerC family	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CMS3_k127_389468_12	679200.HMPREF9333_00340	8.429e-15	86.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_389468_10	501479.ACNW01000043_gene4973	1.96e-19	104.0	2DME0@1|root,32QUX@2|Bacteria,1RJVP@1224|Proteobacteria,2UARA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_389468_2	452637.Oter_2571	1.875e-119	399.0	COG1092@1|root,COG1092@2|Bacteria,46UWW@74201|Verrucomicrobia,3K746@414999|Opitutae	414999|Opitutae	J	Met-10+ like-protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_389468_4	760192.Halhy_6198	1.792e-54	197.0	COG3310@1|root,COG3310@2|Bacteria,4P354@976|Bacteroidetes,1IY2H@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
CMS3_k127_389468_1	246197.MXAN_6908	1.64e-187	602.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2YV8R@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS3_k127_389468_9	1410620.SHLA_43c000560	8.875e-26	124.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,4BCYH@82115|Rhizobiaceae	28211|Alphaproteobacteria	EGIPQ	Acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CMS3_k127_389468_14	199310.c0640	6.545e-09	67.0	2EUDY@1|root,33MWA@2|Bacteria,1NQA6@1224|Proteobacteria,1SH1I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_389468_7	1219080.VEZ01S_37_01680	1.512e-34	148.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RRKU@1236|Gammaproteobacteria,1XSY6@135623|Vibrionales	135623|Vibrionales	M	COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1	fkpA	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_389468_8	563192.HMPREF0179_02751	4.178e-31	136.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,42RI1@68525|delta/epsilon subdivisions,2WNBG@28221|Deltaproteobacteria,2MB6T@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_389468_11	745310.G432_17410	3.098e-16	91.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VA81@28211|Alphaproteobacteria,2K7PZ@204457|Sphingomonadales	204457|Sphingomonadales	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS3_k127_389468_5	95619.PM1_0220825	4.519e-49	185.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1SJCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_389468_6	370438.PTH_0992	8.484e-39	159.0	COG1611@1|root,COG1611@2|Bacteria,1V2D7@1239|Firmicutes,24KYJ@186801|Clostridia,262X1@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM TIGR00725 family protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS3_k127_389468_13	1210884.HG799464_gene11056	7.194e-13	79.0	COG1371@1|root,COG1371@2|Bacteria,2J0RY@203682|Planctomycetes	203682|Planctomycetes	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
CMS3_k127_389468_0	886293.Sinac_5138	2.894e-212	673.0	COG1690@1|root,COG1690@2|Bacteria,2IWY4@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS3_k127_389468_3	502025.Hoch_1530	1.857e-72	267.0	COG3203@1|root,COG3203@2|Bacteria,1QVA0@1224|Proteobacteria,42P8X@68525|delta/epsilon subdivisions,2WM47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,FG-GAP_2
CMS3_k127_3900528_2	765420.OSCT_1373	1.273e-28	132.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_3900528_1	661478.OP10G_1826	9.451e-34	149.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF5011,FG-GAP_2,NHL
CMS3_k127_3900528_4	1408428.JNJP01000045_gene1969	3.997e-07	61.0	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,42SGS@68525|delta/epsilon subdivisions,2WPQ9@28221|Deltaproteobacteria,2MB1H@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3900528_0	1267533.KB906733_gene3472	5.398e-87	319.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_3900528_3	1211815.CBYP010000056_gene3336	2.143e-09	63.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4ESRE@85013|Frankiales	201174|Actinobacteria	T	FHA domain containing protein	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
CMS3_k127_3909061_0	247490.KSU1_D1028	2.098e-103	355.0	COG1200@1|root,COG1200@2|Bacteria,2IX1Q@203682|Planctomycetes	203682|Planctomycetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS3_k127_3909061_1	452637.Oter_0628	1.403e-09	64.0	COG0457@1|root,COG1652@1|root,COG0457@2|Bacteria,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_3918952_16	344747.PM8797T_23916	1.405e-23	104.0	COG2355@1|root,COG2355@2|Bacteria,2IXYG@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase M19 renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_3918952_3	1424334.W822_18305	1.371e-136	445.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VKAV@28216|Betaproteobacteria,3T22D@506|Alcaligenaceae	28216|Betaproteobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
CMS3_k127_3918952_14	1173264.KI913949_gene2283	3.72e-27	120.0	COG0801@1|root,COG0801@2|Bacteria,1G5NF@1117|Cyanobacteria,1HB2Y@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS3_k127_3918952_13	1499967.BAYZ01000145_gene6206	1.136e-30	128.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS3_k127_3918952_5	370438.PTH_1466	2.364e-82	281.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,267CB@186807|Peptococcaceae	186801|Clostridia	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3918952_7	1123508.JH636449_gene7349	1.246e-75	282.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3918952_9	1120985.AUMI01000015_gene1555	4.301e-44	166.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4H4EM@909932|Negativicutes	909932|Negativicutes	S	Bacterial transferase hexapeptide repeat protein	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS3_k127_3918952_4	1142394.PSMK_10130	8.947e-109	376.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2IY1G@203682|Planctomycetes	203682|Planctomycetes	P	COG0038 Chloride channel protein EriC	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS3_k127_3918952_6	1329516.JPST01000038_gene2742	1.213e-79	276.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,27AY1@186824|Thermoactinomycetaceae	91061|Bacilli	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	glxR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS3_k127_3918952_2	195253.Syn6312_2520	3.411e-146	472.0	COG0372@1|root,COG0372@2|Bacteria,1G1DI@1117|Cyanobacteria,1GZB1@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.gltA	Citrate_synt
CMS3_k127_3918952_1	1142394.PSMK_18270	7.189e-256	829.0	COG0841@1|root,COG0841@2|Bacteria,2IY0K@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_3918952_18	1172190.M947_04805	4.82e-17	95.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42T1D@68525|delta/epsilon subdivisions,2YPK5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_3918952_15	1380394.JADL01000021_gene1868	2.021e-26	120.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2JSB6@204441|Rhodospirillales	204441|Rhodospirillales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS3_k127_3918952_23	246437.XP_006149880.1	3.233e-07	63.0	28JDX@1|root,2QRSW@2759|Eukaryota,39UZE@33154|Opisthokonta,3BBYE@33208|Metazoa,3D30Z@33213|Bilateria,484IH@7711|Chordata,48XR4@7742|Vertebrata,3JEQV@40674|Mammalia,35FW0@314146|Euarchontoglires	33208|Metazoa	S	Nudix (nucleoside diphosphate linked moiety X)-type motif 22	NUDT22	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0008768,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031974,GO:0031981,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046872,GO:0070013	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3918952_11	1110502.TMO_2005	7.504e-39	151.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2U9MT@28211|Alphaproteobacteria,2JSNG@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG1335 Amidases related to nicotinamidase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS3_k127_3918952_19	1142394.PSMK_00320	4.909e-14	79.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_3918952_22	595460.RRSWK_04012	3.524e-08	62.0	COG0848@1|root,COG0848@2|Bacteria,2J088@203682|Planctomycetes	203682|Planctomycetes	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_3918952_10	344747.PM8797T_23726	1.895e-40	159.0	COG0811@1|root,COG0811@2|Bacteria,2IZCS@203682|Planctomycetes	203682|Planctomycetes	U	COG0811 Biopolymer transport	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_3918952_20	314230.DSM3645_19318	5.247e-14	85.0	COG2304@1|root,COG2304@2|Bacteria,2J0MU@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_3
CMS3_k127_3918952_21	530564.Psta_2874	2.019e-08	59.0	28QTZ@1|root,2ZD9B@2|Bacteria,2J48Y@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3918952_12	314230.DSM3645_22576	1.043e-34	147.0	COG4191@1|root,COG4191@2|Bacteria,2IYZD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_3918952_0	1539298.JO41_10020	0.0	1151.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2J5JP@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_3918952_8	112098.XP_008612912.1	6.156e-58	230.0	2EKKU@1|root,2SQGG@2759|Eukaryota	2759|Eukaryota	O	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3918952_17	378806.STAUR_5004	1.356e-22	111.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2YVXU@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS3_k127_3924381_2	326427.Cagg_3284	5.872e-10	71.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
CMS3_k127_3924381_1	1122176.KB903565_gene3401	4.603e-25	121.0	COG3591@1|root,COG4935@1|root,COG3591@2|Bacteria,COG4935@2|Bacteria,4NG2K@976|Bacteroidetes,1IY1U@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the peptidase S1B family	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
CMS3_k127_3924381_0	1303518.CCALI_00290	9.732e-308	962.0	COG0542@1|root,COG0542@2|Bacteria	2|Bacteria	O	response to heat	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_3942113_3	443143.GM18_3477	5.776e-122	409.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,42PS0@68525|delta/epsilon subdivisions,2WJU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM aminoacyl-histidine dipeptidase	-	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_3942113_12	224325.AF_1672	1.163e-13	77.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
CMS3_k127_3942113_8	1123508.JH636439_gene853	1.429e-37	148.0	COG2606@1|root,COG2606@2|Bacteria,2J1EW@203682|Planctomycetes	203682|Planctomycetes	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS3_k127_3942113_9	177437.HRM2_31280	1.142e-35	141.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2MJT3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS3_k127_3942113_6	1142394.PSMK_29610	7.535e-52	198.0	COG1234@1|root,COG1234@2|Bacteria,2IWSW@203682|Planctomycetes	203682|Planctomycetes	S	of the beta-lactamase	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS3_k127_3942113_0	246197.MXAN_6038	8.948e-241	767.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,437TW@68525|delta/epsilon subdivisions,2X33B@28221|Deltaproteobacteria,2YU23@29|Myxococcales	28221|Deltaproteobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_3942113_7	344747.PM8797T_07909	9.166e-41	160.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_3942113_11	1347342.BN863_7850	7.105e-22	109.0	COG3291@1|root,COG3291@2|Bacteria,4NF2V@976|Bacteroidetes,1I0CG@117743|Flavobacteriia	976|Bacteroidetes	S	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD_3
CMS3_k127_3942113_5	1265505.ATUG01000002_gene2237	6.503e-53	203.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
CMS3_k127_3942113_4	1121920.AUAU01000004_gene751	2.881e-100	345.0	COG1748@1|root,COG1748@2|Bacteria,3Y84N@57723|Acidobacteria	57723|Acidobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS3_k127_3942113_10	344747.PM8797T_18674	1.444e-33	143.0	COG0697@1|root,COG0697@2|Bacteria,2IZW8@203682|Planctomycetes	203682|Planctomycetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_3942113_1	1519464.HY22_05590	1.008e-221	721.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
CMS3_k127_3942113_2	1237149.C900_03217	7.226e-142	456.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47JKD@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.85	ko:K00128,ko:K10217	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_3954241_9	633149.Bresu_2520	1.133e-10	63.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,2U76N@28211|Alphaproteobacteria,2KGJ2@204458|Caulobacterales	204458|Caulobacterales	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS3_k127_3954241_3	1317122.ATO12_14575	4.926e-100	347.0	COG0815@1|root,COG0815@2|Bacteria,4NMJK@976|Bacteroidetes,1I4UN@117743|Flavobacteriia,2YH3Q@290174|Aquimarina	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_3954241_7	1379698.RBG1_1C00001G0682	5.609e-16	90.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS3_k127_3954241_1	243090.RB12434	6.572e-147	488.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_3954241_0	1291050.JAGE01000001_gene2735	1.097e-148	501.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS3_k127_3954241_2	1195236.CTER_2542	6.501e-129	422.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS3_k127_3954241_4	351160.RCIA125	1.338e-83	286.0	COG1606@1|root,arCOG00043@2157|Archaea,2XV2X@28890|Euryarchaeota,2N9N2@224756|Methanomicrobia	224756|Methanomicrobia	S	PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase,QueC
CMS3_k127_3954241_8	349163.Acry_1031	2.369e-13	85.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,2JQYU@204441|Rhodospirillales	204441|Rhodospirillales	Q	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
CMS3_k127_3954241_6	324602.Caur_0299	8.878e-19	101.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_3954241_10	324602.Caur_0300	1.513e-05	55.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3954241_5	518766.Rmar_0830	5.633e-73	255.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1FJ4A@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
CMS3_k127_3955802_0	570967.JMLV01000002_gene1772	8.007e-108	357.0	COG0665@1|root,COG0665@2|Bacteria,1MXD1@1224|Proteobacteria,2TTDG@28211|Alphaproteobacteria,2JQZU@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_3955802_6	713586.KB900536_gene575	3.212e-14	79.0	2EJUZ@1|root,33DJM@2|Bacteria,1NIYD@1224|Proteobacteria,1SGV4@1236|Gammaproteobacteria,1WZJR@135613|Chromatiales	135613|Chromatiales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS3_k127_3955802_2	575540.Isop_3093	1.768e-69	248.0	COG0472@1|root,COG0472@2|Bacteria,2IXB8@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS3_k127_3955802_5	1042209.HK44_011305	1e-14	87.0	COG5305@1|root,COG5305@2|Bacteria,1R97A@1224|Proteobacteria,1RYHP@1236|Gammaproteobacteria,1YUN5@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3955802_7	42256.RradSPS_1814	2.621e-12	79.0	COG5305@1|root,COG5305@2|Bacteria,2HPE5@201174|Actinobacteria,4CQS9@84995|Rubrobacteria	84995|Rubrobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3955802_1	404589.Anae109_0137	6.379e-76	271.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS3_k127_3955802_3	1193181.BN10_1300016	3.35e-28	122.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3955802_4	411467.BACCAP_03832	5.537e-24	103.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3971520_1	1266925.JHVX01000005_gene1979	6.418e-07	51.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,372EX@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_3971520_0	1190603.AJYD01000012_gene1229	4.685e-23	113.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RWZS@1236|Gammaproteobacteria,1XYQZ@135623|Vibrionales	135623|Vibrionales	MQ	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10_C
CMS3_k127_3973200_8	1142394.PSMK_15660	1.225e-48	186.0	COG3147@1|root,COG3147@2|Bacteria,2IXFB@203682|Planctomycetes	203682|Planctomycetes	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3973200_17	309801.trd_1504	0.0002971	53.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi,27Y36@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS3_k127_3973200_3	1142394.PSMK_15640	2.735e-105	355.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3973200_14	1458275.AZ34_09270	1.402e-11	77.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,4AA31@80864|Comamonadaceae	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS3_k127_3973200_13	158190.SpiGrapes_2806	2.048e-28	126.0	COG0330@1|root,COG0330@2|Bacteria,2J5TU@203691|Spirochaetes	2|Bacteria	O	HflC and HflK could regulate a protease	hflC2	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS3_k127_3973200_16	237368.SCABRO_02158	1.646e-07	64.0	COG0330@1|root,COG0330@2|Bacteria,2IYWQ@203682|Planctomycetes	203682|Planctomycetes	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS3_k127_3973200_6	1142394.PSMK_15560	4.05e-52	196.0	COG1277@1|root,COG1277@2|Bacteria,2IYX5@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS3_k127_3973200_1	1210884.HG799462_gene8899	3.609e-126	424.0	COG2382@1|root,COG2382@2|Bacteria,2J2KX@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_3973200_5	1297742.A176_05483	4.817e-57	208.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2Z0A2@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS3_k127_3973200_0	886293.Sinac_4828	4.55e-165	537.0	COG0498@1|root,COG0498@2|Bacteria,2IXKE@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3973200_9	756272.Plabr_2002	1.304e-46	181.0	COG1994@1|root,COG1994@2|Bacteria,2J04B@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_3973200_11	1142394.PSMK_23290	2.061e-38	155.0	COG0705@1|root,COG0705@2|Bacteria,2J0D1@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_3973200_10	765952.PUV_14650	4.661e-46	174.0	COG0494@1|root,COG0494@2|Bacteria,2JGDU@204428|Chlamydiae	204428|Chlamydiae	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_3973200_2	344747.PM8797T_14619	6.33e-123	407.0	COG0743@1|root,COG0743@2|Bacteria,2IY3M@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS3_k127_3973200_4	1142394.PSMK_24590	5.029e-64	247.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CMS3_k127_3973200_12	886293.Sinac_5143	1.761e-34	137.0	COG0103@1|root,COG0103@2|Bacteria,2J01J@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS3_k127_3973200_7	862517.HMPREF9225_0766	4.183e-50	182.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,22GIV@1570339|Peptoniphilaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS3_k127_3973200_15	1254432.SCE1572_04870	2.689e-08	65.0	29X8Q@1|root,30IY3@2|Bacteria,1QZTR@1224|Proteobacteria,43CNP@68525|delta/epsilon subdivisions,2X7VZ@28221|Deltaproteobacteria,2YYEQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3976769_1	1396418.BATQ01000014_gene4346	1.098e-24	116.0	COG1216@1|root,COG5309@1|root,COG1216@2|Bacteria,COG5309@2|Bacteria,46SAC@74201|Verrucomicrobia,2IV7T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3976769_2	485916.Dtox_4271	7.843e-21	104.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_3976769_0	1541065.JRFE01000014_gene1218	1.861e-60	220.0	2EBP9@1|root,335PE@2|Bacteria	2|Bacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_3997467_14	443143.GM18_0931	1.236e-33	141.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42ZN4@68525|delta/epsilon subdivisions,2WV34@28221|Deltaproteobacteria,43VPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_3997467_19	443143.GM18_1019	7.401e-27	117.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_3997467_22	880073.Calab_1270	1.375e-15	91.0	2ENA5@1|root,33FXV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3997467_11	243231.GSU3225	7.11e-63	231.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,43AJ0@68525|delta/epsilon subdivisions,2X5Z8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3997467_2	338969.Rfer_0259	2.579e-155	511.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,2VMWI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_3997467_18	247490.KSU1_C0404	1.414e-28	133.0	COG1333@1|root,COG1333@2|Bacteria,2J0U6@203682|Planctomycetes	203682|Planctomycetes	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CMS3_k127_3997467_7	404589.Anae109_2747	4.213e-103	357.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WPT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS3_k127_3997467_21	452637.Oter_4030	3.913e-16	91.0	COG0793@1|root,COG3577@1|root,COG0793@2|Bacteria,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asp_protease_2,PDZ_2,Peptidase_S41
CMS3_k127_3997467_0	344747.PM8797T_20903	3.74e-198	645.0	COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes	203682|Planctomycetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS3_k127_3997467_23	368408.Tpen_0975	2.722e-06	53.0	COG1918@1|root,arCOG02102@2157|Archaea	2157|Archaea	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS3_k127_3997467_10	530564.Psta_1412	1.875e-94	345.0	COG0784@1|root,COG3290@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,2IYR0@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
CMS3_k127_3997467_16	864702.OsccyDRAFT_1406	4.361e-29	136.0	COG0642@1|root,COG2205@2|Bacteria,1G2I4@1117|Cyanobacteria,1H7VC@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9
CMS3_k127_3997467_15	379066.GAU_3352	2.532e-32	131.0	COG1528@1|root,COG1528@2|Bacteria,1ZUFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rubrerythrin	-	-	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS3_k127_3997467_8	449447.MAE_22550	1.869e-101	340.0	COG2041@1|root,COG2041@2|Bacteria,1G169@1117|Cyanobacteria	1117|Cyanobacteria	S	Oxidoreductase molybdopterin binding	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CMS3_k127_3997467_4	118163.Ple7327_3743	2.595e-123	404.0	COG2008@1|root,COG2008@2|Bacteria,1G4PN@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_3997467_6	42256.RradSPS_0187	1.82e-112	386.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4CQV5@84995|Rubrobacteria	84995|Rubrobacteria	EU	Peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_3997467_5	1121289.JHVL01000009_gene1462	9.516e-113	381.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,36DHD@31979|Clostridiaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
CMS3_k127_3997467_13	1278073.MYSTI_01248	1.924e-38	152.0	COG4403@1|root,COG4403@2|Bacteria,1NCPK@1224|Proteobacteria	1224|Proteobacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3997467_12	386456.JQKN01000014_gene3139	7.299e-46	172.0	COG3797@1|root,arCOG08236@2157|Archaea,2Y1GJ@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS3_k127_3997467_9	1121413.JMKT01000009_gene1936	3.415e-96	321.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2WJR5@28221|Deltaproteobacteria,2MAEE@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	LysM,MS_channel,TM_helix
CMS3_k127_3997467_20	153948.NAL212_0192	7.926e-22	105.0	COG5549@1|root,COG5549@2|Bacteria,1PE84@1224|Proteobacteria,2WC16@28216|Betaproteobacteria,37458@32003|Nitrosomonadales	28216|Betaproteobacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3997467_3	649638.Trad_0907	3.922e-132	436.0	COG4284@1|root,COG4284@2|Bacteria	2|Bacteria	G	Utp--glucose-1-phosphate uridylyltransferase	CP_1013	-	2.7.7.23,2.7.7.83	ko:K00972,ko:K11442	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS3_k127_3997467_1	530564.Psta_3673	5.097e-178	574.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_3997467_17	1122612.AUBA01000002_gene1931	5.84e-29	119.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,2KEB3@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_4003411_0	1340493.JNIF01000003_gene2146	3.887e-47	175.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_4003411_2	234267.Acid_2836	2.09e-11	65.0	COG1943@1|root,COG1943@2|Bacteria,3Y8QI@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_4003411_1	1185876.BN8_02804	9.406e-24	106.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
CMS3_k127_4003414_0	1379698.RBG1_1C00001G1527	6.984e-106	364.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,fn3
CMS3_k127_4004482_1	1391646.AVSU01000072_gene2955	5.915e-15	77.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,25SQY@186804|Peptostreptococcaceae	186801|Clostridia	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS3_k127_4004482_0	1385935.N836_31000	2.146e-55	205.0	COG0457@1|root,COG0457@2|Bacteria,1G2CI@1117|Cyanobacteria,1HHY4@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
CMS3_k127_4004482_2	243365.CV_4026	1.382e-10	72.0	COG2244@1|root,COG2244@2|Bacteria,1QZC3@1224|Proteobacteria	1224|Proteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_4028083_1	1396141.BATP01000060_gene4560	1.469e-155	517.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CMS3_k127_4028083_6	314230.DSM3645_11631	9.854e-10	66.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_4028083_0	1267535.KB906767_gene447	2.617e-167	561.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_4028083_4	314230.DSM3645_11631	1.375e-39	155.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_4028083_3	1288826.MSNKSG1_11023	5.029e-141	500.0	COG1800@1|root,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4028083_5	7227.FBpp0304622	8.146e-14	85.0	KOG1217@1|root,KOG3594@1|root,KOG4475@1|root,KOG1217@2759|Eukaryota,KOG1219@2759|Eukaryota,KOG4475@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera,45X8G@7214|Drosophilidae	33208|Metazoa	T	Worm-specific repeat type 1	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007399,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0022008,GO:0022404,GO:0030154,GO:0030182,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048468,GO:0048513,GO:0048563,GO:0048569,GO:0048666,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
CMS3_k127_4028083_2	1123508.JH636439_gene1170	6.361e-149	477.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,2J2R4@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_4077140_3	1142394.PSMK_19750	9.194e-19	93.0	COG1974@1|root,COG1974@2|Bacteria,2IZCV@203682|Planctomycetes	203682|Planctomycetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS3_k127_4077140_2	382464.ABSI01000010_gene3558	1.112e-90	314.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_4077140_1	382464.ABSI01000010_gene3557	3.261e-110	366.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_4077140_0	485913.Krac_10500	4.058e-172	569.0	COG0553@1|root,COG0553@2|Bacteria,2G5JY@200795|Chloroflexi	200795|Chloroflexi	L	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
CMS3_k127_4078313_2	335543.Sfum_1753	0.0007402	52.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2MRB3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transport system involved in gliding motility auxiliary component-like	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_4078313_1	247490.KSU1_C0523	5.748e-42	163.0	COG1277@1|root,COG1277@2|Bacteria,2J0HW@203682|Planctomycetes	203682|Planctomycetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS3_k127_4078313_0	247490.KSU1_C0522	3.276e-91	309.0	COG1131@1|root,COG1131@2|Bacteria,2IX20@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4087226_1	1131730.BAVI_09601	1.956e-70	250.0	COG0599@1|root,COG0599@2|Bacteria,1W0GJ@1239|Firmicutes	1239|Firmicutes	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_4087226_4	318996.AXAZ01000043_gene2086	5.248e-13	69.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria,3JVA3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_4087226_3	1122603.ATVI01000007_gene1789	3.489e-26	111.0	COG0346@1|root,COG0346@2|Bacteria,1RK3P@1224|Proteobacteria	1224|Proteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4087226_5	1078020.KEK_04292	2.29e-09	65.0	COG0346@1|root,COG0346@2|Bacteria,2IG7M@201174|Actinobacteria,237QZ@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4087226_2	935557.ATYB01000009_gene1118	7.679e-66	242.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HEAT_2,Rhodanese,TPR_16,TPR_19,TPR_8,TolB_N
CMS3_k127_4087226_0	1185652.USDA257_c13580	1.112e-165	540.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TolB_N
CMS3_k127_4128833_6	443143.GM18_0613	3.139e-47	196.0	COG3656@1|root,COG3656@2|Bacteria	2|Bacteria	N	Periplasmic Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF2271,FGE-sulfatase,Kelch_3,TIG
CMS3_k127_4128833_10	521393.JH806633_gene1439	3.752e-08	66.0	COG1333@1|root,COG1333@2|Bacteria,2GMGH@201174|Actinobacteria,4D3U7@85005|Actinomycetales	201174|Actinobacteria	O	ResB-like family	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS3_k127_4128833_5	635013.TherJR_1027	2.741e-53	197.0	COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,24BCK@186801|Clostridia,260YW@186807|Peptococcaceae	186801|Clostridia	O	PFAM Cytochrome c assembly protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS3_k127_4128833_3	635013.TherJR_2857	6.525e-177	567.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,264YF@186807|Peptococcaceae	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4128833_9	1123368.AUIS01000011_gene1181	3.364e-15	81.0	COG1959@1|root,COG1959@2|Bacteria,1RE3F@1224|Proteobacteria,1TDGB@1236|Gammaproteobacteria,2NCVI@225057|Acidithiobacillales	225057|Acidithiobacillales	K	TIGRFAM Transcriptional regulator, Rrf2	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_4128833_7	323098.Nwi_0773	9.097e-43	169.0	COG2010@1|root,COG2010@2|Bacteria,1MYNE@1224|Proteobacteria,2V9Z1@28211|Alphaproteobacteria,3K5DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_4128833_0	1121920.AUAU01000008_gene1619	0.0	1815.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
CMS3_k127_4128833_1	1121920.AUAU01000008_gene1618	3.482e-229	718.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
CMS3_k127_4128833_8	1121920.AUAU01000008_gene1617	1.179e-23	111.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
CMS3_k127_4128833_4	1121920.AUAU01000008_gene1616	6.98e-58	211.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	narI	GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204	1.7.5.1	ko:K00370,ko:K00374,ko:K02575	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00615,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.8,5.A.3.1	-	iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897	Nitrate_red_gam
CMS3_k127_4128833_2	344747.PM8797T_29278	8.16e-178	575.0	COG2223@1|root,COG2223@2|Bacteria,2IYP8@203682|Planctomycetes	203682|Planctomycetes	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
CMS3_k127_4130512_2	272568.GDI1551	1.495e-06	49.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2U1DA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CMS3_k127_4130512_0	391625.PPSIR1_08496	3.756e-50	190.0	COG2234@1|root,COG2234@2|Bacteria,1PY1F@1224|Proteobacteria,4350U@68525|delta/epsilon subdivisions,2WZBN@28221|Deltaproteobacteria,2Z1SK@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_4130512_1	338969.Rfer_1205	6.293e-11	64.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,4AEEU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4139303_0	690850.Desaf_2629	3.41e-64	240.0	29MQ2@1|root,308MT@2|Bacteria,1NG1Y@1224|Proteobacteria,4365R@68525|delta/epsilon subdivisions,2X0PX@28221|Deltaproteobacteria,2MD1E@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4143450_7	402777.KB235898_gene5413	1.321e-45	170.0	COG3576@1|root,COG3576@2|Bacteria,1G2UH@1117|Cyanobacteria,1HAZT@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_4143450_6	331869.BAL199_21719	1.895e-47	177.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,4BQQU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	ahpD	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_4143450_9	378806.STAUR_5333	9.561e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,1NCEF@1224|Proteobacteria,431EH@68525|delta/epsilon subdivisions,2WWCR@28221|Deltaproteobacteria,2YVII@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_6,TetR_N
CMS3_k127_4143450_16	1142394.PSMK_07570	1.01e-05	58.0	2A5PN@1|root,30UEH@2|Bacteria,2J3F8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4143450_14	118166.JH976537_gene4219	1.136e-13	85.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1H889@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_4143450_3	1297742.A176_01664	1.215e-79	279.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YW82@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_4143450_11	402777.KB235904_gene2694	1.681e-20	106.0	COG1807@1|root,COG1807@2|Bacteria,1GI8H@1117|Cyanobacteria,1HETH@1150|Oscillatoriales	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4143450_8	1120973.AQXL01000116_gene310	4.819e-40	156.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,278G7@186823|Alicyclobacillaceae	91061|Bacilli	D	Maf-like protein	maf	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS3_k127_4143450_4	867903.ThesuDRAFT_02352	1.754e-76	269.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WCII@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS3_k127_4143450_0	1142394.PSMK_11030	8.954e-135	443.0	COG0285@1|root,COG0285@2|Bacteria,2IX24@203682|Planctomycetes	203682|Planctomycetes	H	folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_4143450_12	1094980.Mpsy_2531	2.217e-18	93.0	COG0475@1|root,COG0490@1|root,arCOG01955@2157|Archaea,arCOG01970@2157|Archaea,2XT4U@28890|Euryarchaeota,2N9B6@224756|Methanomicrobia	224756|Methanomicrobia	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS3_k127_4143450_5	153948.NAL212_2583	3.011e-49	190.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,2VMK4@28216|Betaproteobacteria,373TU@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_4143450_13	1449346.JQMO01000003_gene4427	7.313e-15	82.0	COG3404@1|root,COG3404@2|Bacteria,2IIRF@201174|Actinobacteria,2M47G@2063|Kitasatospora	201174|Actinobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
CMS3_k127_4143450_10	530564.Psta_4395	4.96e-31	131.0	COG3222@1|root,COG3222@2|Bacteria,2J0B9@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS3_k127_4143450_1	586413.CCDL010000001_gene1683	4.305e-133	433.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,23JRD@182709|Oceanobacillus	91061|Bacilli	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_4143450_2	243090.RB10500	4.802e-130	429.0	COG0126@1|root,COG0126@2|Bacteria,2IYIS@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS3_k127_4143450_15	1054213.HMPREF9946_03548	9.621e-12	72.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,2JQ7Q@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_4152721_10	338966.Ppro_1017	2.331e-13	74.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
CMS3_k127_4152721_2	1125863.JAFN01000001_gene568	4.182e-155	500.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
CMS3_k127_4152721_8	314278.NB231_01898	2.852e-19	99.0	28N07@1|root,2ZB6S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4152721_11	511.JT27_13670	0.000105	54.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,3T1S3@506|Alcaligenaceae	28216|Betaproteobacteria	O	peptidyl-prolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS3_k127_4152721_1	886293.Sinac_6434	1.108e-277	891.0	COG1197@1|root,COG1197@2|Bacteria,2IWV4@203682|Planctomycetes	203682|Planctomycetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS3_k127_4152721_4	886293.Sinac_1196	1.149e-75	272.0	COG0349@1|root,COG0349@2|Bacteria,2IY8T@203682|Planctomycetes	203682|Planctomycetes	J	COG0349 Ribonuclease D	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS3_k127_4152721_0	247490.KSU1_B0370	2.212e-295	929.0	COG0188@1|root,COG0188@2|Bacteria,2IY0U@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS3_k127_4152721_6	1894.JOER01000058_gene3221	6.01e-58	231.0	COG0265@1|root,COG2319@1|root,COG0265@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2,WD40
CMS3_k127_4152721_3	1267533.KB906733_gene3472	1.03e-103	377.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_4152721_7	448385.sce0681	6.39e-52	191.0	COG1595@1|root,COG1595@2|Bacteria,1N3BR@1224|Proteobacteria	1224|Proteobacteria	K	rna polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_4152721_5	1197477.IA57_11075	2.157e-72	278.0	COG2885@1|root,COG3209@1|root,COG3227@1|root,COG3291@1|root,COG3391@1|root,COG5184@1|root,COG5563@1|root,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,COG5563@2|Bacteria,4PMAH@976|Bacteroidetes,1I2AU@117743|Flavobacteriia	976|Bacteroidetes	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4152721_12	1254432.SCE1572_20735	0.0002346	55.0	2BPY0@1|root,32IRR@2|Bacteria,1Q1YS@1224|Proteobacteria,437KR@68525|delta/epsilon subdivisions,2X2UV@28221|Deltaproteobacteria,2YUI3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4152721_9	1168034.FH5T_21985	4.479e-14	74.0	COG3595@1|root,COG3595@2|Bacteria,4NW0T@976|Bacteroidetes,2G3DA@200643|Bacteroidia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS3_k127_4167557_20	1565129.JSFF01000027_gene3321	7.979e-16	89.0	2ARWY@1|root,31H8T@2|Bacteria,1QEYJ@1224|Proteobacteria,1TBXH@1236|Gammaproteobacteria,2QD75@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4167557_10	344747.PM8797T_11911	1.484e-52	207.0	COG0681@1|root,COG0681@2|Bacteria,2IY6X@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS3_k127_4167557_7	886293.Sinac_1883	4.935e-85	291.0	COG1137@1|root,COG1137@2|Bacteria,2IYUP@203682|Planctomycetes	203682|Planctomycetes	S	ABC-type (unclassified) transport system ATPase	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_4167557_16	278963.ATWD01000001_gene2053	1.163e-37	158.0	COG1994@1|root,COG1994@2|Bacteria,3Y58P@57723|Acidobacteria,2JJUI@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_4167557_19	1440053.JOEI01000035_gene6140	4.96e-25	120.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
CMS3_k127_4167557_13	1463856.JOHY01000008_gene924	2.487e-41	164.0	COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria	201174|Actinobacteria	I	Diacylglycerol kinase	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
CMS3_k127_4167557_2	266117.Rxyl_2111	1.439e-120	399.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_4167557_11	1487953.JMKF01000047_gene2140	5.194e-52	193.0	COG0560@1|root,COG0560@2|Bacteria,1GAKQ@1117|Cyanobacteria	1117|Cyanobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,LPG_synthase_TM
CMS3_k127_4167557_1	483219.LILAB_01140	9.866e-187	635.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
CMS3_k127_4167557_14	269799.Gmet_0363	8.659e-40	157.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,43SI8@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_4167557_15	1210884.HG799465_gene11378	1.374e-39	152.0	COG1778@1|root,COG1778@2|Bacteria,2IZM6@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
CMS3_k127_4167557_21	936455.KI421499_gene6420	2.26e-05	53.0	2CGEX@1|root,32U4B@2|Bacteria,1MWWW@1224|Proteobacteria,2TT01@28211|Alphaproteobacteria,3JSQK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1579)	MA20_43845	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS3_k127_4167557_0	237368.SCABRO_01759	4.462e-228	722.0	COG1217@1|root,COG1217@2|Bacteria,2IY3Q@203682|Planctomycetes	203682|Planctomycetes	T	membrane GTPase involved in stress response	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_4167557_4	518766.Rmar_0100	1.427e-103	349.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the citrate synthase family	prpC	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_4167557_6	1303518.CCALI_01699	7.318e-91	309.0	COG2513@1|root,COG2513@2|Bacteria	2|Bacteria	G	methylisocitrate lyase activity	prpB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	iECNA114_1301.ECNA114_0319,iECP_1309.ECP_0407	PEP_mutase
CMS3_k127_4167557_3	1232437.KL662020_gene704	4.217e-119	410.0	COG3591@1|root,COG5640@1|root,COG3591@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,PKD,PPC,Trypsin,Trypsin_2
CMS3_k127_4167557_5	1499967.BAYZ01000103_gene3758	3.49e-97	347.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000103_gene3758|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4167557_12	1078085.HMPREF1210_00717	3.053e-45	176.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,26FD5@186818|Planococcaceae	91061|Bacilli	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	-	-	-	ko:K13012,ko:K19428	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
CMS3_k127_4167557_18	1123242.JH636435_gene3026	5.27e-32	145.0	COG1413@1|root,COG1413@2|Bacteria,2IZ04@203682|Planctomycetes	203682|Planctomycetes	C	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_4167557_9	56780.SYN_00042	3.279e-71	249.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42QVM@68525|delta/epsilon subdivisions,2WN3E@28221|Deltaproteobacteria,2MRIY@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sir2 family	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS3_k127_4167557_17	211165.AJLN01000033_gene2648	6.554e-34	136.0	COG3631@1|root,COG3631@2|Bacteria,1GAK6@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_4167557_8	402777.KB235898_gene5413	1.155e-76	264.0	COG3576@1|root,COG3576@2|Bacteria,1G2UH@1117|Cyanobacteria,1HAZT@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_417355_0	595460.RRSWK_05503	1.173e-103	384.0	COG1572@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG3420@1|root,COG4257@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG4257@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_417355_1	1150599.MPHLEI_02788	1.319e-29	139.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
CMS3_k127_4212938_0	446470.Snas_0537	5.075e-81	300.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
CMS3_k127_4212938_2	471854.Dfer_0264	1.375e-17	98.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CMS3_k127_4212938_1	1121930.AQXG01000001_gene1526	2.569e-21	110.0	COG0737@1|root,COG2374@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	xynX5	-	3.2.1.8	ko:K01181,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Endonuclease_1,Exo_endo_phos,LTD,SLH,SprB
CMS3_k127_4233330_1	639030.JHVA01000001_gene1885	2.376e-10	66.0	2A8SF@1|root,30XV5@2|Bacteria,3Y8QM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4233330_0	555793.WSK_4047	2.016e-11	77.0	28NHI@1|root,2ZBJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4238769_0	1121396.KB893072_gene1226	8.786e-42	176.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MHQU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS3_k127_4239098_2	1121104.AQXH01000003_gene325	1.424e-62	226.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,1IRKN@117747|Sphingobacteriia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_4239098_1	886293.Sinac_5943	1.621e-122	406.0	COG3635@1|root,COG3635@2|Bacteria,2IXCZ@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
CMS3_k127_4239098_3	1210884.HG799462_gene8806	5.279e-39	153.0	COG0457@1|root,COG0457@2|Bacteria,2J0X4@203682|Planctomycetes	203682|Planctomycetes	CO	Bacterial Fe(2+) trafficking	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic,TPR_2
CMS3_k127_4239098_4	370438.PTH_1786	1.772e-08	65.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,261TT@186807|Peptococcaceae	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
CMS3_k127_4239098_0	391625.PPSIR1_36969	8.352e-265	825.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,42PUK@68525|delta/epsilon subdivisions,2WIN4@28221|Deltaproteobacteria,2YU7Y@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS3_k127_4248675_1	1382356.JQMP01000003_gene1584	2.63e-165	539.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,27XKK@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS3_k127_4248675_4	264462.Bd3087	4.374e-52	200.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2MTMT@213481|Bdellovibrionales,2WKJS@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
CMS3_k127_4248675_2	1396141.BATP01000060_gene4560	4.776e-160	536.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CMS3_k127_4248675_5	314230.DSM3645_11631	7.959e-47	179.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_4248675_6	717773.Thicy_1475	1.596e-13	86.0	COG2911@1|root,COG2911@2|Bacteria,1QXZF@1224|Proteobacteria,1T55Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Haemagg_act
CMS3_k127_4248675_0	234267.Acid_4393	4.956e-180	598.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4248675_3	661478.OP10G_0834	3.285e-103	345.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_4250160_2	309801.trd_1809	5.027e-30	130.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_4250160_0	644282.Deba_2444	1.219e-174	559.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,42NEJ@68525|delta/epsilon subdivisions,2WM86@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_4250160_1	1379698.RBG1_1C00001G0600	8.442e-48	178.0	COG1670@1|root,COG1670@2|Bacteria,2NPXX@2323|unclassified Bacteria	2|Bacteria	J	Acetyltransferase (GNAT) domain	yokL1	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_4250160_3	497964.CfE428DRAFT_1667	3.687e-24	109.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_425162_2	234267.Acid_7677	2.219e-42	163.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_425162_1	1121957.ATVL01000014_gene1459	3.879e-85	316.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_425162_0	344747.PM8797T_25371	2.508e-108	370.0	COG0475@1|root,COG0475@2|Bacteria,2J51D@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_425162_3	756272.Plabr_2420	4.379e-18	88.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS3_k127_426385_5	743722.Sph21_2801	8.699e-14	72.0	COG0845@1|root,COG0845@2|Bacteria,4NRKU@976|Bacteroidetes,1J18S@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
CMS3_k127_426385_0	1121459.AQXE01000014_gene351	0.0	1768.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2M9PX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
CMS3_k127_426385_4	448385.sce9323	1.628e-29	133.0	COG3527@1|root,COG3527@2|Bacteria	2|Bacteria	Q	acetolactate decarboxylase activity	budA	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	AAL_decarboxy
CMS3_k127_426385_3	518766.Rmar_2460	1.102e-48	183.0	COG3182@1|root,COG3182@2|Bacteria,4NFK9@976|Bacteroidetes	976|Bacteroidetes	S	Iron-regulated membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
CMS3_k127_426385_1	243090.RB7299	9.41e-200	632.0	COG0189@1|root,COG0569@1|root,COG0189@2|Bacteria,COG0569@2|Bacteria,2IYT1@203682|Planctomycetes	203682|Planctomycetes	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,TrkA_C
CMS3_k127_426385_2	344747.PM8797T_03685	1.102e-166	531.0	COG3608@1|root,COG3608@2|Bacteria,2IX28@203682|Planctomycetes	203682|Planctomycetes	S	succinate dehydrogenase subunit	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS3_k127_4265593_2	448385.sce5537	3.226e-20	95.0	2DBQY@1|root,2ZAHD@2|Bacteria,1QYTK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
CMS3_k127_4265593_0	1254432.SCE1572_39315	4.739e-92	333.0	COG3055@1|root,COG3055@2|Bacteria,1QE0Q@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF1929)	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF1929,Glyoxal_oxid_N,Kelch_1,Kelch_4,Kelch_6,RicinB_lectin_2
CMS3_k127_4265593_1	215803.DB30_5025	2.601e-24	114.0	2A4S1@1|root,30TDF@2|Bacteria,1PD68@1224|Proteobacteria,438NE@68525|delta/epsilon subdivisions,2X3WE@28221|Deltaproteobacteria,2YXBX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4265593_3	1095769.CAHF01000023_gene438	1.645e-08	60.0	2C3QT@1|root,32YUW@2|Bacteria,1P8VZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4269507_0	479437.Elen_2607	2.12e-28	123.0	COG0863@1|root,COG0863@2|Bacteria,2GP2V@201174|Actinobacteria,4CXKX@84998|Coriobacteriia	84998|Coriobacteriia	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
CMS3_k127_4269507_1	1463856.JOHY01000007_gene777	7.096e-14	85.0	COG3757@1|root,COG3757@2|Bacteria,2HUW8@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,DUF1906
CMS3_k127_4282875_6	686340.Metal_2137	2.286e-48	177.0	COG0454@1|root,COG0456@2|Bacteria,1N29T@1224|Proteobacteria,1S8SC@1236|Gammaproteobacteria,1XFVH@135618|Methylococcales	135618|Methylococcales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_4282875_3	644076.SCH4B_3710	1.338e-66	233.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria,4NDIY@97050|Ruegeria	28211|Alphaproteobacteria	S	Phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CMS3_k127_4282875_4	1123503.KB908064_gene1160	1.399e-62	220.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CMS3_k127_4282875_5	329726.AM1_3688	9.084e-55	196.0	COG4675@1|root,COG4675@2|Bacteria,1G7MZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CMS3_k127_4282875_9	926560.KE387023_gene1193	3.453e-19	93.0	2EJ72@1|root,33CY7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4282875_11	479432.Sros_8326	1.171e-09	66.0	COG1734@1|root,COG1734@2|Bacteria,2IQS3@201174|Actinobacteria,4EKK5@85012|Streptosporangiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS3_k127_4282875_2	1210884.HG799462_gene8037	1.348e-115	389.0	COG2204@1|root,COG2204@2|Bacteria,2IY95@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4282875_7	1128421.JAGA01000003_gene3019	7.352e-45	171.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS3_k127_4282875_8	985665.HPL003_27725	7.495e-31	136.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,26R7U@186822|Paenibacillaceae	91061|Bacilli	S	Permease	yrrI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_4282875_10	1002340.AFCF01000062_gene690	7.842e-17	86.0	COG2329@1|root,COG2329@2|Bacteria,1N1IT@1224|Proteobacteria,2UCHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_4282875_1	243090.RB11142	1.289e-118	400.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_4282875_0	1565129.JSFF01000026_gene1237	1.005e-234	747.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1SZS1@1236|Gammaproteobacteria,2Q9VB@267890|Shewanellaceae	1236|Gammaproteobacteria	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_4308248_5	1121438.JNJA01000011_gene1815	1.584e-35	145.0	COG1861@1|root,COG1861@2|Bacteria,1RG42@1224|Proteobacteria,42SUK@68525|delta/epsilon subdivisions,2WPW0@28221|Deltaproteobacteria,2MGNI@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM acylneuraminate cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
CMS3_k127_4308248_0	1120951.AUBG01000004_gene2492	5.074e-104	348.0	COG2089@1|root,COG2089@2|Bacteria,4NEKD@976|Bacteroidetes,1HYI2@117743|Flavobacteriia	976|Bacteroidetes	M	Sialic acid synthase	neuB	-	2.5.1.132,2.5.1.56	ko:K01654,ko:K21279	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
CMS3_k127_4308248_4	661478.OP10G_3301	2.775e-37	149.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria	2|Bacteria	S	3-deoxy-manno-octulosonate-8-phosphatase activity	neuA	GO:0003674,GO:0003824,GO:0008781,GO:0016740,GO:0016772,GO:0016779,GO:0070567	2.5.1.55,2.7.7.43,2.7.7.92,3.1.3.103,3.1.3.45	ko:K00983,ko:K01627,ko:K03270,ko:K21055,ko:K21749	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03254,R03350,R04215,R11440	RC00017,RC00152,RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
CMS3_k127_4308248_3	383372.Rcas_0769	4.951e-41	169.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
CMS3_k127_4308248_2	866895.HBHAL_1435	4.922e-56	207.0	COG0500@1|root,COG2226@2|Bacteria,1VQ19@1239|Firmicutes,4HVFK@91061|Bacilli,3NFZH@45667|Halobacillus	91061|Bacilli	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_4308248_6	479434.Sthe_0858	5.577e-10	70.0	COG0500@1|root,COG2226@2|Bacteria,2G8WR@200795|Chloroflexi,27YA7@189775|Thermomicrobia	189775|Thermomicrobia	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_4308248_1	283942.IL0547	7.834e-62	217.0	COG0110@1|root,COG0110@2|Bacteria,1PEZ6@1224|Proteobacteria,1RUSR@1236|Gammaproteobacteria,2QH1X@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS3_k127_4319425_0	290397.Adeh_3200	1.367e-74	278.0	COG3303@1|root,COG3303@2|Bacteria,1NT38@1224|Proteobacteria,43CCP@68525|delta/epsilon subdivisions,2X7NK@28221|Deltaproteobacteria,2YZY2@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4320239_2	378806.STAUR_4286	3.031e-35	142.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,430JB@68525|delta/epsilon subdivisions,2WVTU@28221|Deltaproteobacteria,2YWQ0@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_4320239_0	886293.Sinac_5961	1.965e-52	202.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_4320239_1	234267.Acid_0847	6.234e-36	156.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
CMS3_k127_4320239_3	309807.SRU_0982	1.848e-33	131.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1FJQG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS3_k127_4320844_10	1283287.KB822588_gene1152	5.188e-05	48.0	COG1595@1|root,COG3291@1|root,COG1595@2|Bacteria,COG3291@2|Bacteria,2GJFK@201174|Actinobacteria,4DP7W@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
CMS3_k127_4320844_2	309807.SRU_1925	7.061e-50	188.0	COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1FJIE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	pabB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS3_k127_4320844_4	1298593.TOL_2611	1.53e-28	124.0	COG0393@1|root,COG0393@2|Bacteria,1N6BK@1224|Proteobacteria,1SAFJ@1236|Gammaproteobacteria,1XMNR@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CMS3_k127_4320844_3	1229172.JQFA01000002_gene2384	6.99e-38	145.0	COG0393@1|root,COG0393@2|Bacteria,1G7AD@1117|Cyanobacteria,1HC1G@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CMS3_k127_4320844_7	1210884.HG799463_gene10266	7.525e-19	91.0	COG0227@1|root,COG0227@2|Bacteria,2J0SS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS3_k127_4320844_6	1123255.JHYS01000012_gene1340	5.722e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2VQPE@28216|Betaproteobacteria,4ADGF@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4320844_0	314230.DSM3645_21894	4.151e-119	391.0	COG1087@1|root,COG1087@2|Bacteria,2IY22@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_4320844_8	1123508.JH636447_gene8078	1.542e-12	72.0	2E4ZM@1|root,32ZT9@2|Bacteria,2J122@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4320844_1	1142394.PSMK_11820	7.633e-108	361.0	COG2019@1|root,COG2019@2|Bacteria	2|Bacteria	F	adenylate kinase activity	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_17
CMS3_k127_4320844_5	1123320.KB889607_gene9530	2.317e-24	110.0	COG2310@1|root,COG2340@1|root,COG2310@2|Bacteria,COG2340@2|Bacteria,2GNN0@201174|Actinobacteria	201174|Actinobacteria	T	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,TerD
CMS3_k127_4325529_0	1347368.HG964408_gene7109	8.656e-40	172.0	COG2247@1|root,COG2931@1|root,COG3210@1|root,COG4632@1|root,COG2247@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4632@2|Bacteria,1UMUN@1239|Firmicutes,4IU0J@91061|Bacilli	91061|Bacilli	G	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
CMS3_k127_4325529_1	926550.CLDAP_20910	9.42e-38	166.0	COG1319@1|root,COG3266@1|root,COG3391@1|root,COG1319@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	FAD_binding_5
CMS3_k127_4375150_2	255470.cbdbA1335	4.213e-41	174.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,34CT3@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HisKA_7TM
CMS3_k127_4375150_0	1123278.KB893452_gene737	2.787e-92	342.0	COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47Y2E@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y
CMS3_k127_4375150_1	502025.Hoch_5683	2.316e-51	189.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2YY0V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS3_k127_4377891_2	394221.Mmar10_0219	1.032e-26	110.0	COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria,43XZD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	COG3316 Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
CMS3_k127_4377891_0	1207063.P24_13303	9.66e-43	159.0	2F34Y@1|root,33VZN@2|Bacteria,1REIT@1224|Proteobacteria,2U7FZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_4377891_1	1380394.JADL01000010_gene4274	1.643e-29	127.0	COG5424@1|root,COG5424@2|Bacteria,1PVPF@1224|Proteobacteria,2U38I@28211|Alphaproteobacteria,2JYA4@204441|Rhodospirillales	204441|Rhodospirillales	H	Iron-containing redox enzyme	-	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	Haem_oxygenas_2
CMS3_k127_4377891_3	1120983.KB894577_gene3515	0.0002151	49.0	COG1638@1|root,COG1638@2|Bacteria,1NTFS@1224|Proteobacteria,2U1QM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_4394363_2	439496.RBY4I_1056	1.382e-30	126.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2UDE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_4394363_0	999549.KI421513_gene2344	5.868e-40	155.0	2E9PG@1|root,333VW@2|Bacteria,1NEU7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4394363_1	396588.Tgr7_3139	1.109e-33	143.0	COG5295@1|root,COG5295@2|Bacteria,1N8QZ@1224|Proteobacteria	1224|Proteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4399575_3	67352.JODS01000013_gene5061	9.892e-05	51.0	COG1846@1|root,COG1846@2|Bacteria,2IER9@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS3_k127_4399575_0	575540.Isop_1950	1.559e-110	384.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2IX9E@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b subunit of the bc complex	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B
CMS3_k127_4399575_1	344747.PM8797T_32370	1.503e-29	124.0	COG0723@1|root,COG0723@2|Bacteria,2J13H@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Rieske 2Fe-2S domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
CMS3_k127_4399575_2	1157708.KB907469_gene50	4.417e-06	59.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,4ADJG@80864|Comamonadaceae	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS3_k127_444926_1	1348657.M622_04425	2.02e-36	146.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_444926_0	1120936.KB907208_gene1207	5.536e-57	213.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4449833_0	1205680.CAKO01000038_gene1920	9.934e-85	292.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,2JU60@204441|Rhodospirillales	204441|Rhodospirillales	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_4449833_1	946362.XP_004993652.1	6.869e-45	183.0	COG3914@1|root,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PH,TPR_10,TPR_12,TPR_7,TPR_8
CMS3_k127_4475148_1	1117647.M5M_10790	5.317e-106	355.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,1J4HK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_4475148_0	1348663.KCH_09200	9.168e-128	423.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,2M1EP@2063|Kitasatospora	201174|Actinobacteria	S	Pfam Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_4475148_2	384765.SIAM614_02591	2.197e-12	68.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TT5E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_4475265_0	555088.DealDRAFT_1177	5.487e-228	724.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,42KC8@68298|Syntrophomonadaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS3_k127_4475265_3	397287.C807_03162	3.533e-49	181.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,27MET@186928|unclassified Lachnospiraceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS3_k127_4475265_2	379066.GAU_1218	2.532e-51	189.0	COG1825@1|root,COG1825@2|Bacteria,1ZTHZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS3_k127_4475265_1	1379270.AUXF01000005_gene526	7.71e-145	465.0	COG0462@1|root,COG0462@2|Bacteria,1ZT7Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS3_k127_4475265_4	1519464.HY22_04905	7.575e-11	62.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
CMS3_k127_4492605_5	1142394.PSMK_07620	2.666e-37	160.0	COG1538@1|root,COG1538@2|Bacteria,2J2W4@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_4492605_1	314230.DSM3645_19378	5.767e-92	312.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_4492605_3	1123242.JH636435_gene1534	6.873e-71	267.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4492605_6	859657.RPSI07_0559	4.037e-32	138.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,1K08P@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS3_k127_4492605_0	338966.Ppro_2629	8.414e-97	327.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_4492605_4	321327.CYA_2681	3.403e-38	149.0	COG0669@1|root,COG0669@2|Bacteria,1G4Z8@1117|Cyanobacteria,1H0IQ@1129|Synechococcus	1117|Cyanobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_4492605_2	1121459.AQXE01000001_gene2816	2.019e-85	296.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2M8KS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS3_k127_4492605_7	204669.Acid345_0086	8.964e-09	67.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	psbU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02237,ko:K02719	ko00195,ko01100,map00195,map01100	M00429	-	-	ko00000,ko00001,ko00002,ko00194,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,PsbU
CMS3_k127_4499080_0	1089550.ATTH01000001_gene1831	3.266e-126	435.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
CMS3_k127_4499080_4	502025.Hoch_2677	3.579e-17	96.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_4499080_1	497964.CfE428DRAFT_5098	5.044e-59	231.0	COG1075@1|root,COG1404@1|root,COG3055@1|root,COG3391@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.1.3.6,3.2.1.4	ko:K01179,ko:K03333,ko:K12287	ko00500,ko00984,ko01100,ko01120,map00500,map00984,map01100,map01120	-	R01459,R06200,R11307,R11308	RC00146	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin
CMS3_k127_4499080_2	1278073.MYSTI_03395	3.448e-52	209.0	COG3591@1|root,COG3591@2|Bacteria,1QDPR@1224|Proteobacteria,434U5@68525|delta/epsilon subdivisions,2X90W@28221|Deltaproteobacteria,2Z1CH@29|Myxococcales	28221|Deltaproteobacteria	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Trypsin_2
CMS3_k127_4500909_1	335543.Sfum_3244	4.753e-182	578.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2MRBG@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_4500909_0	661478.OP10G_0773	2.604e-288	911.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_4508712_2	234267.Acid_5749	4.743e-67	253.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_4508712_1	1121920.AUAU01000006_gene330	9.992e-106	377.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4508712_0	1047013.AQSP01000112_gene368	1.436e-155	498.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_4528613_11	314230.DSM3645_09677	8.728e-43	172.0	COG0682@1|root,COG0682@2|Bacteria,2IZQ2@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT,PDZ
CMS3_k127_4528613_6	1120973.AQXL01000134_gene1576	5.577e-88	299.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,2784W@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS3_k127_4528613_13	1449126.JQKL01000043_gene1887	1.77e-27	121.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,268PT@186813|unclassified Clostridiales	186801|Clostridia	K	ECF sigma factor	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4528613_15	742727.HMPREF9447_00689	1.505e-05	57.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK71@815|Bacteroidaceae	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS3_k127_4528613_4	671143.DAMO_0269	6.635e-95	320.0	COG2877@1|root,COG2877@2|Bacteria,2NNQB@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the KdsA family	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS3_k127_4528613_8	314230.DSM3645_22646	3.08e-77	276.0	COG0006@1|root,COG0006@2|Bacteria,2IX8W@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_4528613_12	521674.Plim_0064	6.728e-38	148.0	COG0511@1|root,COG0511@2|Bacteria,2IZJ6@203682|Planctomycetes	203682|Planctomycetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS3_k127_4528613_1	1123242.JH636434_gene4769	3.045e-172	552.0	COG0439@1|root,COG0439@2|Bacteria,2IWZV@203682|Planctomycetes	203682|Planctomycetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS3_k127_4528613_0	234267.Acid_5892	4.514e-210	668.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4528613_5	1267535.KB906767_gene5368	1.177e-90	321.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene5368|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4528613_14	1194972.MVAC_10747	1.029e-06	57.0	COG3688@1|root,COG3688@2|Bacteria,2HS1T@201174|Actinobacteria,23A4M@1762|Mycobacteriaceae	201174|Actinobacteria	S	YacP-like NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN_YacP
CMS3_k127_4528613_10	290397.Adeh_0179	6.745e-46	171.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2YVDP@29|Myxococcales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS3_k127_4528613_2	204669.Acid345_1052	1.567e-136	488.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
CMS3_k127_4528613_9	234267.Acid_0687	8.977e-66	259.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	2|Bacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
CMS3_k127_4528613_7	1434929.X946_1416	1.938e-79	304.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2VZN8@28216|Betaproteobacteria,1KGFG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17
CMS3_k127_4528613_3	1379698.RBG1_1C00001G0607	4.076e-136	459.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
CMS3_k127_4548840_8	1141663.OOC_07413	0.0009173	52.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,3Z7IU@586|Providencia	1236|Gammaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575	Methyltransf_11
CMS3_k127_4548840_4	748449.Halha_2243	1.773e-38	153.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	ATP-grasp_3,HAD_2
CMS3_k127_4548840_3	471223.GWCH70_3255	2.764e-68	250.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	ATP-grasp_3,Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_4548840_1	266117.Rxyl_2558	1.644e-95	327.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4CPMK@84995|Rubrobacteria	84995|Rubrobacteria	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS3_k127_4548840_6	530564.Psta_2444	8.414e-38	151.0	COG1143@1|root,COG1143@2|Bacteria,2IYY8@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS3_k127_4548840_7	1123508.JH636441_gene3187	8.173e-30	126.0	COG0838@1|root,COG0838@2|Bacteria,2IZMM@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS3_k127_4548840_2	1123242.JH636436_gene424	1.732e-85	285.0	COG0377@1|root,COG0377@2|Bacteria,2IY3F@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS3_k127_4548840_5	880073.Calab_2691	3.822e-38	154.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS3_k127_4548840_0	314230.DSM3645_08562	4.3e-105	347.0	COG0649@1|root,COG0649@2|Bacteria,2IY7J@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS3_k127_4582028_0	886293.Sinac_6482	0.0	1176.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS3_k127_4582028_2	886293.Sinac_4159	1.658e-62	224.0	COG1881@1|root,COG1881@2|Bacteria,2J1MM@203682|Planctomycetes	203682|Planctomycetes	G	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP,YHYH
CMS3_k127_4582028_1	1123508.JH636439_gene680	4.49e-220	692.0	COG1012@1|root,COG1012@2|Bacteria,2IXV2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4582028_3	620914.JH621251_gene2415	3.115e-05	53.0	COG2273@1|root,COG3401@1|root,COG4733@1|root,COG2273@2|Bacteria,COG3401@2|Bacteria,COG4733@2|Bacteria,4P1G2@976|Bacteroidetes,1I78P@117743|Flavobacteriia,2YKT3@290174|Aquimarina	976|Bacteroidetes	G	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4592141_5	439235.Dalk_1248	1.776e-37	156.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_4592141_4	1216976.AX27061_1395	2.506e-52	190.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,3T3SA@506|Alcaligenaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CMS3_k127_4592141_0	314230.DSM3645_18221	1.834e-147	484.0	COG0215@1|root,COG0215@2|Bacteria,2IX9C@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS3_k127_4592141_1	314345.SPV1_12687	6.817e-78	268.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria	1224|Proteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_4592141_3	264462.Bd2576	3.164e-53	206.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2MTMK@213481|Bdellovibrionales,2WJAU@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Histidine kinase	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	2CSK_N,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
CMS3_k127_4592141_10	1280949.HAD_00645	5.286e-05	53.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TTXE@28211|Alphaproteobacteria,43X3V@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Glyoxalase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_4592141_7	1415630.U771_25815	6.466e-23	108.0	COG0500@1|root,COG0500@2|Bacteria,1NIZX@1224|Proteobacteria,1T2CR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_4592141_2	713586.KB900536_gene1869	1.461e-75	263.0	COG0515@1|root,COG0515@2|Bacteria	713586.KB900536_gene1869|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4592141_9	985255.APHJ01000024_gene1172	1.572e-05	59.0	COG3391@1|root,COG3391@2|Bacteria,4NK97@976|Bacteroidetes,1HYP5@117743|Flavobacteriia,2P7C8@244698|Gillisia	976|Bacteroidetes	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
CMS3_k127_4592141_6	1192034.CAP_8435	2.67e-33	151.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	B_lectin,SseB
CMS3_k127_4594677_1	234267.Acid_4940	0.0009908	53.0	COG1409@1|root,COG1657@1|root,COG4412@1|root,COG1409@2|Bacteria,COG1657@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K14647,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	CARDB,Peptidase_M30
CMS3_k127_4594677_0	717605.Theco_2613	1.238e-210	663.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,26T3H@186822|Paenibacillaceae	91061|Bacilli	C	Converts isocitrate to alpha ketoglutarate	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_46170_0	1207063.P24_05952	1.728e-66	231.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JQY7@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_46170_2	1168059.KB899087_gene1061	4.402e-09	59.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS3_k127_46170_1	1122137.AQXF01000002_gene377	1.995e-43	171.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,2UIQ4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4628524_7	515635.Dtur_0968	1.446e-26	111.0	COG0173@1|root,COG0173@2|Bacteria	2|Bacteria	J	aspartate-tRNA(Asn) ligase activity	aspS	GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN678.aspS,iSFV_1184.SFV_1868	GAD,tRNA-synt_2,tRNA_anti-codon
CMS3_k127_4628524_5	298653.Franean1_1515	1.354e-37	152.0	COG1011@1|root,COG1011@2|Bacteria,2HU26@201174|Actinobacteria,4EWJA@85013|Frankiales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase_like
CMS3_k127_4628524_12	1123242.JH636434_gene4822	1.32e-05	58.0	COG4783@1|root,COG4783@2|Bacteria,2J4VV@203682|Planctomycetes	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	ko:K11935	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	DUF560,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CMS3_k127_4628524_10	237368.SCABRO_03101	1.013e-14	79.0	COG1943@1|root,COG1943@2|Bacteria,2J4E8@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4628524_3	886293.Sinac_2461	4.833e-47	181.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_4628524_1	471854.Dfer_2772	4.611e-75	270.0	COG1134@1|root,COG1134@2|Bacteria,4NEDM@976|Bacteroidetes,47JN7@768503|Cytophagia	976|Bacteroidetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_4628524_2	1128421.JAGA01000001_gene2334	2.413e-53	201.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	bplH	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
CMS3_k127_4628524_4	1121439.dsat_1297	7.09e-41	164.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,42Q1D@68525|delta/epsilon subdivisions,2WJYJ@28221|Deltaproteobacteria,2M88U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4628524_9	1499968.TCA2_5947	4.311e-15	85.0	COG0500@1|root,COG1216@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria,1U21D@1239|Firmicutes,4IBI9@91061|Bacilli,270JI@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_4628524_8	1121438.JNJA01000003_gene2914	3.15e-18	94.0	COG4122@1|root,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,439ZI@68525|delta/epsilon subdivisions,2X2GU@28221|Deltaproteobacteria,2MDMY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS3_k127_4628524_11	751944.HALDL1_11055	1.931e-10	73.0	COG0438@1|root,arCOG01403@2157|Archaea,2XUVC@28890|Euryarchaeota,24185@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_4628524_6	331113.SNE_A23130	3.202e-29	136.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2JFR7@204428|Chlamydiae	204428|Chlamydiae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_4628524_0	326427.Cagg_3388	1.947e-75	266.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS3_k127_4666195_4	765912.Thimo_1862	4.267e-75	255.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,1S0RN@1236|Gammaproteobacteria,1X0GG@135613|Chromatiales	135613|Chromatiales	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
CMS3_k127_4666195_6	313628.LNTAR_20803	1.336e-39	154.0	COG0853@1|root,COG0853@2|Bacteria	2|Bacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS3_k127_4666195_5	358681.BBR47_10650	2.3e-53	200.0	COG0702@1|root,COG0702@2|Bacteria,1TT3N@1239|Firmicutes,4HB09@91061|Bacilli,26W1M@186822|Paenibacillaceae	91061|Bacilli	GM	NAD(P)H-binding	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
CMS3_k127_4666195_0	243090.RB8562	4.104e-217	687.0	COG0696@1|root,COG0696@2|Bacteria,2IX1K@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Sulfatase,iPGM_N
CMS3_k127_4666195_7	1144275.COCOR_07442	2.75e-34	147.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42S9W@68525|delta/epsilon subdivisions,2WNX4@28221|Deltaproteobacteria,2YUXR@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8
CMS3_k127_4666195_2	314230.DSM3645_09717	2.546e-161	520.0	COG2204@1|root,COG2204@2|Bacteria,2IYIG@203682|Planctomycetes	203682|Planctomycetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4666195_1	1120936.KB907209_gene1559	1.438e-170	547.0	COG4992@1|root,COG4992@2|Bacteria,2GK0J@201174|Actinobacteria,4EHYP@85012|Streptosporangiales	201174|Actinobacteria	E	Aminotransferase class-III	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_4666195_3	1150474.JQJI01000015_gene639	5.28e-107	355.0	COG0078@1|root,COG0078@2|Bacteria,2GCHI@200918|Thermotogae	200918|Thermotogae	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1097	OTCace,OTCace_N
CMS3_k127_4666195_8	1499967.BAYZ01000137_gene104	5.349e-34	139.0	COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria	2|Bacteria	E	Amino acid kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
CMS3_k127_4666451_0	498848.TaqDRAFT_4878	6.134e-109	375.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4681056_4	234267.Acid_7393	0.0004827	43.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_4681056_3	926569.ANT_03070	8.73e-15	89.0	COG5295@1|root,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4681056_1	204669.Acid345_2049	1.471e-56	225.0	2AWXU@1|root,31NVG@2|Bacteria,3Y98N@57723|Acidobacteria,2JP54@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4681056_2	1267535.KB906767_gene2919	5.434e-34	137.0	COG1228@1|root,COG1228@2|Bacteria,3Y4IP@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_4691927_3	1283300.ATXB01000001_gene1937	9.404e-102	340.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1XE21@135618|Methylococcales	135618|Methylococcales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS3_k127_4691927_5	1051632.TPY_1473	9.543e-60	217.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS3_k127_4691927_13	879212.DespoDRAFT_02067	3.495e-11	65.0	COG3526@1|root,COG3526@2|Bacteria,1PSK4@1224|Proteobacteria,433FM@68525|delta/epsilon subdivisions,2WX6C@28221|Deltaproteobacteria,2MP5Z@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
CMS3_k127_4691927_0	237368.SCABRO_00256	1.94e-211	668.0	COG1158@1|root,COG1158@2|Bacteria,2IXV3@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS3_k127_4691927_6	1210884.HG799464_gene10500	3.018e-43	165.0	COG0237@1|root,COG0237@2|Bacteria,2J02E@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS3_k127_4691927_14	749414.SBI_04356	8.448e-06	53.0	COG0346@1|root,COG0346@2|Bacteria,2II17@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4691927_8	290397.Adeh_1122	1.896e-29	125.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria,2YVPM@29|Myxococcales	28221|Deltaproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
CMS3_k127_4691927_1	886293.Sinac_1688	9.327e-209	657.0	COG3033@1|root,COG3033@2|Bacteria,2J41D@203682|Planctomycetes	203682|Planctomycetes	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_4691927_12	661478.OP10G_1142	1.053e-11	73.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CMS3_k127_4691927_10	622637.KE124774_gene1191	9.25e-17	91.0	COG1633@1|root,COG1633@2|Bacteria,1N073@1224|Proteobacteria,2UE47@28211|Alphaproteobacteria,370DX@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
CMS3_k127_4691927_2	1142394.PSMK_06290	4.982e-122	401.0	COG0158@1|root,COG0158@2|Bacteria,2IWT3@203682|Planctomycetes	203682|Planctomycetes	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
CMS3_k127_4691927_11	247490.KSU1_B0277	5.931e-14	80.0	COG5000@1|root,COG5000@2|Bacteria,2IYXF@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_4691927_4	1379698.RBG1_1C00001G1719	2.087e-62	224.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_4691927_7	1121382.JQKG01000033_gene3125	5.17e-34	148.0	COG3170@1|root,COG3170@2|Bacteria,1WKQT@1297|Deinococcus-Thermus	2|Bacteria	NU	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Astacin,PPC
CMS3_k127_4691927_9	324602.Caur_0299	2.156e-19	104.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_471315_0	56780.SYN_01983	1.06e-238	754.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MR7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_471315_1	1123508.JH636440_gene2072	5.429e-35	139.0	COG4747@1|root,COG4747@2|Bacteria,2IZK3@203682|Planctomycetes	203682|Planctomycetes	S	COG4747 ACT domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_471315_2	1123242.JH636436_gene152	4.107e-34	137.0	COG3399@1|root,COG3399@2|Bacteria,2IZMN@203682|Planctomycetes	203682|Planctomycetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_471315_3	886293.Sinac_6219	1.206e-33	143.0	COG4948@1|root,COG4948@2|Bacteria,2IX42@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase muconate lactonizing enzyme	-	-	5.1.1.20,5.5.1.1	ko:K01856,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS3_k127_4716500_3	102129.Lepto7375DRAFT_6630	7.932e-26	111.0	COG4424@1|root,COG4424@2|Bacteria,1GQFR@1117|Cyanobacteria,1HD1A@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
CMS3_k127_4716500_5	1391646.AVSU01000072_gene2955	1.07e-18	94.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,25SQY@186804|Peptostreptococcaceae	186801|Clostridia	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS3_k127_4716500_2	1142394.PSMK_18480	1.175e-37	159.0	COG1989@1|root,COG1989@2|Bacteria,2IZQ8@203682|Planctomycetes	203682|Planctomycetes	NOU	Bacterial Peptidase A24 N-terminal domain	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS3_k127_4716500_4	1131269.AQVV01000015_gene2042	1.002e-21	96.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CMS3_k127_4716500_1	401526.TcarDRAFT_0216	3.078e-67	244.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,4H2B6@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
CMS3_k127_4716500_0	1121428.DESHY_110173___1	2.224e-98	329.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,260GK@186807|Peptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS3_k127_4754345_2	243231.GSU0769	3.264e-25	107.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
CMS3_k127_4754345_0	1267535.KB906767_gene2002	2.763e-56	203.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TPMT
CMS3_k127_4756624_1	1297742.A176_05070	2.57e-127	419.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	iron-sulfur binding	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_4756624_0	246197.MXAN_5556	1.164e-206	652.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2YU0I@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
CMS3_k127_4756624_4	483219.LILAB_35255	1.39e-47	176.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2WT1Y@28221|Deltaproteobacteria,2Z0GX@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS3_k127_4756624_3	246197.MXAN_5554	3.713e-48	179.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_4756624_2	1297742.A176_05066	1.841e-93	323.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YY91@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4757040_0	1142394.PSMK_25190	8.326e-178	571.0	COG0160@1|root,COG0160@2|Bacteria,2IYBU@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS3_k127_4757040_1	521674.Plim_2933	4.956e-122	402.0	COG0659@1|root,COG0659@2|Bacteria,2J2QM@203682|Planctomycetes	203682|Planctomycetes	P	Molybdate transporter of MFS superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_MOT1
CMS3_k127_4757040_2	383372.Rcas_3093	7.736e-66	239.0	COG0451@1|root,COG0451@2|Bacteria,2GAMV@200795|Chloroflexi,376SP@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_4757040_3	941449.dsx2_1135	3.19e-27	120.0	COG1216@1|root,COG2242@1|root,COG1216@2|Bacteria,COG2242@2|Bacteria,1N5S1@1224|Proteobacteria,431RF@68525|delta/epsilon subdivisions,2WWS3@28221|Deltaproteobacteria,2ME2J@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_4757040_4	1540221.JQNI01000002_gene2288	1.812e-26	118.0	COG0357@1|root,COG0357@2|Bacteria,1WIYE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS3_k127_4778806_10	1089550.ATTH01000001_gene1831	6.639e-56	218.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
CMS3_k127_4778806_4	706587.Desti_0692	2.632e-87	301.0	COG0674@1|root,COG0674@2|Bacteria,1R4K0@1224|Proteobacteria,42NQJ@68525|delta/epsilon subdivisions,2WJ0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS3_k127_4778806_5	1121405.dsmv_2999	6.594e-72	259.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1R7US@1224|Proteobacteria,42PFT@68525|delta/epsilon subdivisions,2WMBJ@28221|Deltaproteobacteria,2MJ1Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,TPP_enzyme_C
CMS3_k127_4778806_0	908612.HMPREF9720_1069	1.12e-253	812.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,22V18@171550|Rikenellaceae	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS3_k127_4778806_9	1283299.AUKG01000002_gene4961	9.884e-59	213.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CQ53@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS3_k127_4778806_2	237368.SCABRO_00712	5.338e-107	364.0	COG1055@1|root,COG1055@2|Bacteria	2|Bacteria	P	arsenite transmembrane transporter activity	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS3_k127_4778806_11	247490.KSU1_C1247	4.188e-47	176.0	COG0529@1|root,COG0529@2|Bacteria,2IYUQ@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
CMS3_k127_4778806_12	575540.Isop_0255	2.208e-45	181.0	COG2267@1|root,COG2267@2|Bacteria,2IZH7@203682|Planctomycetes	203682|Planctomycetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_4778806_8	243231.GSU1126	3.135e-65	232.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_4778806_6	756272.Plabr_1702	9.56e-70	245.0	COG1043@1|root,COG1043@2|Bacteria,2IZR6@203682|Planctomycetes	203682|Planctomycetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS3_k127_4778806_17	448385.sce1771	5.088e-07	64.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Malectin
CMS3_k127_4778806_1	886293.Sinac_5023	1.917e-159	520.0	COG1190@1|root,COG1190@2|Bacteria,2IXHX@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_4778806_13	1142394.PSMK_12440	7.274e-44	179.0	COG4591@1|root,COG4591@2|Bacteria,2IY15@203682|Planctomycetes	203682|Planctomycetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS3_k127_4778806_7	1123242.JH636436_gene657	3.095e-69	242.0	COG1136@1|root,COG1136@2|Bacteria,2IYZ3@203682|Planctomycetes	203682|Planctomycetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
CMS3_k127_4778806_3	756272.Plabr_2136	1.693e-104	351.0	COG0115@1|root,COG0115@2|Bacteria,2IY3N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_4778806_15	697281.Mahau_2374	3.873e-37	157.0	COG2199@1|root,COG3706@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,42J5P@68295|Thermoanaerobacterales	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_9,Response_reg,TPR_8
CMS3_k127_4778806_14	1089553.Tph_c14230	7.993e-42	168.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_47850_0	1232410.KI421415_gene3122	1.379e-37	149.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CMS3_k127_47850_1	1142394.PSMK_19040	3.172e-37	160.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	AMPK1_CBM,Alpha-amylase,Malt_amylase_C
CMS3_k127_47850_2	911045.PSE_5019	1.644e-11	67.0	2CK9T@1|root,2Z7W9@2|Bacteria,1NEP3@1224|Proteobacteria,2U3MN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_47850_3	452637.Oter_3173	1.715e-10	69.0	2EFI3@1|root,339AJ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
CMS3_k127_4789265_3	436229.JOEH01000026_gene2296	3.28e-48	186.0	COG0457@1|root,COG0457@2|Bacteria,2I9VA@201174|Actinobacteria	201174|Actinobacteria	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
CMS3_k127_4789265_4	991.IW20_04690	3.461e-20	104.0	COG1075@1|root,COG1075@2|Bacteria,4PD0F@976|Bacteroidetes,1IDIF@117743|Flavobacteriia,2NYI4@237|Flavobacterium	976|Bacteroidetes	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
CMS3_k127_4789265_0	768710.DesyoDRAFT_1529	1.085e-224	729.0	COG0243@1|root,COG0243@2|Bacteria,1UYJX@1239|Firmicutes,24DD4@186801|Clostridia,263SM@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_4789265_5	756499.Desde_1889	2.379e-18	94.0	COG3381@1|root,COG3381@2|Bacteria,1VGZ7@1239|Firmicutes,24SRM@186801|Clostridia	186801|Clostridia	S	PFAM cytoplasmic chaperone TorD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
CMS3_k127_4789265_2	234267.Acid_1970	1.81e-93	325.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,DUF2048,Peptidase_S9
CMS3_k127_4789265_1	1123242.JH636434_gene5040	1.476e-141	476.0	COG2217@1|root,COG2217@2|Bacteria,2IX25@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
CMS3_k127_4790711_18	1037409.BJ6T_83010	5.144e-41	158.0	COG3293@1|root,COG3293@2|Bacteria,1NCPP@1224|Proteobacteria	1224|Proteobacteria	L	Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3'	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
CMS3_k127_4790711_14	886293.Sinac_1993	6.069e-55	197.0	COG5609@1|root,COG5609@2|Bacteria,2J0WE@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
CMS3_k127_4790711_32	9785.ENSLAFP00000019630	4.14e-10	71.0	KOG3544@1|root,KOG3544@2759|Eukaryota,38CJN@33154|Opisthokonta,3BAFZ@33208|Metazoa,3CRU5@33213|Bilateria,487EK@7711|Chordata,4951D@7742|Vertebrata,3J630@40674|Mammalia,34SPK@311790|Afrotheria	33208|Metazoa	W	Collagen alpha-6(IV) chain	COL4A6	GO:0005575,GO:0005576,GO:0005581,GO:0005587,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008150,GO:0009987,GO:0012505,GO:0016043,GO:0030198,GO:0031012,GO:0031974,GO:0032991,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0062023,GO:0070013,GO:0071840,GO:0098642,GO:0098644,GO:0098645,GO:0098651,GO:0099080,GO:0099081	-	ko:K06237	ko04151,ko04510,ko04512,ko04926,ko04933,ko04974,ko05146,ko05165,ko05200,ko05222,map04151,map04510,map04512,map04926,map04933,map04974,map05146,map05165,map05200,map05222	-	-	-	ko00000,ko00001,ko00536,ko04147,ko04516	-	-	-	C4,Collagen
CMS3_k127_4790711_15	192952.MM_1794	5.435e-53	199.0	arCOG00372@1|root,arCOG02157@1|root,arCOG02158@1|root,arCOG00372@2157|Archaea,arCOG02157@2157|Archaea,arCOG02158@2157|Archaea,2Y8E6@28890|Euryarchaeota,2N9WT@224756|Methanomicrobia	224756|Methanomicrobia	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
CMS3_k127_4790711_20	1173263.Syn7502_03654	8.357e-34	137.0	COG3861@1|root,COG3861@2|Bacteria,1G5I2@1117|Cyanobacteria	1117|Cyanobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4790711_29	1123393.KB891333_gene2534	4.31e-14	72.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2VYEK@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4790711_17	886293.Sinac_1999	8.542e-48	175.0	COG5609@1|root,COG5609@2|Bacteria,2J0KX@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
CMS3_k127_4790711_33	666685.R2APBS1_1942	1.733e-07	57.0	COG1551@1|root,COG1551@2|Bacteria,1N6PG@1224|Proteobacteria	1224|Proteobacteria	J	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
CMS3_k127_4790711_31	247639.MGP2080_06327	2.254e-12	78.0	COG2885@1|root,COG3468@1|root,COG4447@1|root,COG2885@2|Bacteria,COG3468@2|Bacteria,COG4447@2|Bacteria,1R4WG@1224|Proteobacteria,1RZN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
CMS3_k127_4790711_9	158190.SpiGrapes_0903	5.062e-85	294.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,DUF3494,W_rich_C
CMS3_k127_4790711_8	158190.SpiGrapes_0903	5.652e-87	299.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,DUF3494,W_rich_C
CMS3_k127_4790711_2	530564.Psta_1696	1.704e-140	462.0	COG3064@1|root,COG3064@2|Bacteria,2IXYB@203682|Planctomycetes	203682|Planctomycetes	M	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS3_k127_4790711_27	443143.GM18_3152	2.503e-18	85.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,42XBI@68525|delta/epsilon subdivisions,2WSNB@28221|Deltaproteobacteria,43VX5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
CMS3_k127_4790711_0	717773.Thicy_1179	4.447e-215	680.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_4790711_25	215803.DB30_1542	5.85e-24	106.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2YW0C@29|Myxococcales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
CMS3_k127_4790711_23	1123242.JH636435_gene985	1.407e-28	123.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4790711_19	518766.Rmar_2228	5.763e-40	166.0	COG2203@1|root,COG3829@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
CMS3_k127_4790711_13	870187.Thini_0858	1.036e-63	226.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,460UF@72273|Thiotrichales	72273|Thiotrichales	K	PFAM Response regulator receiver domain	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_4790711_26	314230.DSM3645_21217	2.27e-19	89.0	COG3237@1|root,COG3237@2|Bacteria,2J0JU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
CMS3_k127_4790711_12	306281.AJLK01000150_gene1995	1.652e-72	257.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
CMS3_k127_4790711_34	1234364.AMSF01000088_gene2789	2.74e-07	56.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SGD7@1236|Gammaproteobacteria,1X8RN@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS3_k127_4790711_28	1033802.SSPSH_001698	1.204e-16	82.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SCVB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS3_k127_4790711_24	886293.Sinac_3975	2.263e-24	119.0	COG0810@1|root,COG0810@2|Bacteria,2IZYP@203682|Planctomycetes	203682|Planctomycetes	M	carbohydrate binding	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
CMS3_k127_4790711_4	575540.Isop_3538	1.344e-109	365.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_4790711_16	886293.Sinac_1840	1.917e-52	213.0	COG3170@1|root,COG3170@2|Bacteria,2IX5A@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4790711_7	886293.Sinac_1839	2.933e-89	323.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXY5@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA,VWA_2
CMS3_k127_4790711_11	575540.Isop_3542	2.001e-84	307.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_4790711_10	575540.Isop_3543	8.149e-85	291.0	COG1721@1|root,COG1721@2|Bacteria,2IWV6@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4790711_1	886293.Sinac_1836	5.898e-144	464.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4790711_5	243090.RB10175	1.854e-94	321.0	COG1611@1|root,COG1611@2|Bacteria,2IXIR@203682|Planctomycetes	203682|Planctomycetes	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS3_k127_4790711_21	1179773.BN6_01340	1.868e-31	130.0	COG0454@1|root,COG0456@2|Bacteria,2II52@201174|Actinobacteria,4E3TJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_4790711_6	1210884.HG799473_gene14938	2.788e-89	301.0	COG2120@1|root,COG2120@2|Bacteria,2IY68@203682|Planctomycetes	203682|Planctomycetes	S	PFAM LmbE family protein	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS3_k127_4790711_22	530564.Psta_1574	1.748e-30	124.0	COG1694@1|root,COG1694@2|Bacteria,2J0FY@203682|Planctomycetes	203682|Planctomycetes	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CMS3_k127_4790711_3	530564.Psta_4222	1.706e-111	371.0	COG0825@1|root,COG0825@2|Bacteria,2IX7N@203682|Planctomycetes	203682|Planctomycetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS3_k127_4790711_30	264462.Bd3426	5.748e-14	78.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,430W9@68525|delta/epsilon subdivisions,2MSZJ@213481|Bdellovibrionales,2WW2T@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,Peptidase_M14
CMS3_k127_4794746_3	247490.KSU1_C1333	6.289e-05	53.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_4794746_1	1123242.JH636434_gene4961	4.864e-87	312.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_4794746_0	1210884.HG799464_gene11109	1.037e-101	342.0	COG2805@1|root,COG2805@2|Bacteria,2IXRP@203682|Planctomycetes	2|Bacteria	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_4794746_2	756272.Plabr_2520	5.811e-19	90.0	COG1868@1|root,COG1868@2|Bacteria,2IY74@203682|Planctomycetes	203682|Planctomycetes	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
CMS3_k127_4798200_4	314230.DSM3645_11631	4.944e-38	149.0	COG1595@1|root,COG1595@2|Bacteria,2J3FS@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_4798200_7	1192034.CAP_0870	4.869e-07	63.0	COG4935@1|root,COG5492@1|root,COG4935@2|Bacteria,COG5492@2|Bacteria,1R2U6@1224|Proteobacteria	2|Bacteria	O	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,DUF4215,LRR_5,P_proprotein
CMS3_k127_4798200_3	926550.CLDAP_19490	3.446e-40	171.0	COG1319@1|root,COG2931@1|root,COG3420@1|root,COG1319@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FAD_binding_5
CMS3_k127_4798200_2	591159.ACEZ01000080_gene6517	1.605e-52	190.0	COG1670@1|root,COG1670@2|Bacteria,2IFNY@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferases including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_4798200_6	1267534.KB906756_gene153	6.126e-10	71.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440,SnoaL_2,SnoaL_3
CMS3_k127_4798200_1	631362.Thi970DRAFT_01814	1.169e-59	214.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,1RRGB@1236|Gammaproteobacteria,1X08N@135613|Chromatiales	135613|Chromatiales	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_4798200_0	1304885.AUEY01000104_gene2548	1.271e-108	365.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS3_k127_4824925_6	112098.XP_008615955.1	7.079e-33	150.0	2EN7E@1|root,2SRQ7@2759|Eukaryota	2759|Eukaryota	O	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4824925_3	1499967.BAYZ01000003_gene5884	3.247e-66	233.0	COG2454@1|root,COG2454@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
CMS3_k127_4824925_0	670307.HYPDE_33213	1.612e-158	525.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
CMS3_k127_4824925_9	1111479.AXAR01000003_gene1568	4.398e-08	64.0	COG1846@1|root,COG1846@2|Bacteria,1VQH8@1239|Firmicutes,4IR44@91061|Bacilli,27ABD@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS3_k127_4824925_11	479432.Sros_0899	8.585e-05	53.0	COG5662@1|root,COG5662@2|Bacteria,2GNCC@201174|Actinobacteria,4EKFN@85012|Streptosporangiales	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_4824925_8	1122603.ATVI01000008_gene2311	9.168e-10	66.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1SCRQ@1236|Gammaproteobacteria,1XB8B@135614|Xanthomonadales	135614|Xanthomonadales	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4824925_2	1121456.ATVA01000014_gene604	1.164e-77	272.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,2MGTS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
CMS3_k127_4824925_10	1499967.BAYZ01000097_gene4356	7.818e-05	50.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS3_k127_4824925_4	583355.Caka_1907	8.043e-51	187.0	COG0778@1|root,COG0778@2|Bacteria,46VFV@74201|Verrucomicrobia,3K80J@414999|Opitutae	414999|Opitutae	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_4824925_5	711393.AYRX01000069_gene706	4.138e-46	174.0	COG2329@1|root,COG2329@2|Bacteria,2GIS0@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4937	-	-	-	-	-	-	-	-	-	-	-	-	DUF4937
CMS3_k127_4824925_1	886293.Sinac_2212	1.71e-107	352.0	COG3293@1|root,COG3293@2|Bacteria,2IY34@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CMS3_k127_4835394_0	1288826.MSNKSG1_11023	1.739e-87	330.0	COG1800@1|root,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4835394_3	886293.Sinac_3742	0.0006214	54.0	2EWXN@1|root,33Q91@2|Bacteria,2J1WQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4835394_2	1094980.Mpsy_3151	1.259e-15	93.0	COG5520@1|root,arCOG03769@1|root,arCOG07561@1|root,arCOG03769@2157|Archaea,arCOG07561@2157|Archaea,arCOG09138@2157|Archaea,2XV3J@28890|Euryarchaeota,2NBAU@224756|Methanomicrobia	224756|Methanomicrobia	K	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4835394_1	3218.PP1S186_60V6.1	1.376e-33	145.0	KOG1225@1|root,KOG1225@2759|Eukaryota	2759|Eukaryota	L	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007275,GO:0007399,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0008589,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030182,GO:0031012,GO:0031647,GO:0032501,GO:0032502,GO:0044421,GO:0045880,GO:0048468,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050821,GO:0050896,GO:0051716,GO:0065007,GO:0065008	-	ko:K01691,ko:K06252	ko04151,ko04310,ko04510,ko04512,ko05165,ko05206,map04151,map04310,map04510,map04512,map05165,map05206	-	-	-	ko00000,ko00001,ko00536,ko04516	-	-	-	EGF,EGF_2,WIF,hEGF
CMS3_k127_4837108_3	318167.Sfri_2409	1.993e-18	90.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,1SCJZ@1236|Gammaproteobacteria,2QC6B@267890|Shewanellaceae	1236|Gammaproteobacteria	S	membrane	ybaN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
CMS3_k127_4837108_2	1229909.NSED_04975	4.063e-22	115.0	COG1361@1|root,arCOG04500@1|root,arCOG02079@2157|Archaea,arCOG04500@2157|Archaea	2157|Archaea	O	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CARDB,NosD,S_layer_C
CMS3_k127_4837108_4	1380394.JADL01000004_gene5817	8.58e-11	68.0	COG5349@1|root,COG5349@2|Bacteria,1MZDD@1224|Proteobacteria,2UCM4@28211|Alphaproteobacteria,2JU4P@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS3_k127_4837108_1	215803.DB30_6515	2.524e-116	389.0	COG5505@1|root,COG5505@2|Bacteria,1MW87@1224|Proteobacteria,42RQH@68525|delta/epsilon subdivisions,2WTKY@28221|Deltaproteobacteria,2YTSF@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS3_k127_4837108_0	204669.Acid345_4118	1.014e-136	460.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_4840183_0	1123242.JH636434_gene4156	5.281e-235	746.0	COG3379@1|root,COG3379@2|Bacteria,2J27J@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_4840183_1	1123242.JH636434_gene4155	2.785e-91	306.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_4843906_3	226186.BT_2113	5.315e-131	444.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
CMS3_k127_4843906_0	1267534.KB906755_gene4821	1.152e-196	639.0	COG3345@1|root,COG3345@2|Bacteria,3Y44J@57723|Acidobacteria,2JIVW@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4843906_2	1047013.AQSP01000125_gene2621	3.13e-142	469.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_4843906_1	1515613.HQ37_03905	1.335e-169	562.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia,22WBH@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
CMS3_k127_4843906_5	1267534.KB906755_gene4819	5.7e-106	356.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	mdsC	-	2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS3_k127_4843906_7	585502.HMPREF0645_0024	1.277e-70	252.0	COG1209@1|root,COG1209@2|Bacteria,4NF32@976|Bacteroidetes,2FP9F@200643|Bacteroidia	976|Bacteroidetes	M	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
CMS3_k127_4843906_4	1124780.ANNU01000006_gene2793	1.274e-117	391.0	COG3934@1|root,COG3934@2|Bacteria,4NH10@976|Bacteroidetes,47JD9@768503|Cytophagia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42
CMS3_k127_4843906_11	1463936.JOJI01000016_gene248	0.0008576	48.0	COG1141@1|root,COG1141@2|Bacteria,2IR4H@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
CMS3_k127_4843906_9	671143.DAMO_0994	3.141e-29	124.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_4843906_8	644281.MFS40622_1299	5.86e-68	242.0	COG2048@1|root,arCOG00338@2157|Archaea,2XTWJ@28890|Euryarchaeota,23Q3U@183939|Methanococci	183939|Methanococci	C	heterodisulfide reductase, subunit B	hdrB2	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS3_k127_4843906_10	694440.JOMF01000006_gene468	5.558e-18	97.0	COG2048@1|root,arCOG00964@2157|Archaea,2XXYP@28890|Euryarchaeota,2N9VF@224756|Methanomicrobia	224756|Methanomicrobia	C	heterodisulfide reductase subunit C	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
CMS3_k127_4843906_6	439235.Dalk_1624	3.052e-72	248.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
CMS3_k127_4848521_2	886293.Sinac_6812	4.152e-103	355.0	COG1480@1|root,COG1480@2|Bacteria,2IYP7@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
CMS3_k127_4848521_5	314230.DSM3645_07710	4.278e-21	98.0	COG0319@1|root,COG0319@2|Bacteria,2J0MV@203682|Planctomycetes	203682|Planctomycetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS3_k127_4848521_7	1133850.SHJG_8496	0.0003606	51.0	COG0388@1|root,COG0388@2|Bacteria,2H30B@201174|Actinobacteria	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS3_k127_4848521_3	756272.Plabr_1325	2.059e-68	248.0	COG1253@1|root,COG1253@2|Bacteria,2IZAU@203682|Planctomycetes	203682|Planctomycetes	S	COG1253 Hemolysins and related	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_4848521_1	1121918.ARWE01000001_gene2375	8.308e-204	656.0	COG0531@1|root,COG1762@1|root,COG0531@2|Bacteria,COG1762@2|Bacteria,1MXNJ@1224|Proteobacteria,43A4W@68525|delta/epsilon subdivisions,2X2I0@28221|Deltaproteobacteria,43VI8@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_4848521_6	1380600.AUYN01000007_gene3350	7.273e-07	59.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,4NFCF@976|Bacteroidetes,1HWJE@117743|Flavobacteriia	976|Bacteroidetes	P	Chloride channel protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS3_k127_4848521_4	247490.KSU1_C0398	2.552e-32	128.0	COG0234@1|root,COG0234@2|Bacteria,2J027@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_4848521_0	1142394.PSMK_31900	8.358e-230	723.0	COG0459@1|root,COG0459@2|Bacteria,2IXA7@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_4860289_0	247490.KSU1_B0556	2.869e-62	223.0	COG0673@1|root,COG0673@2|Bacteria,2IXAX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_4860289_1	886293.Sinac_2339	4.017e-09	68.0	COG4927@1|root,COG4927@2|Bacteria,2IYD9@203682|Planctomycetes	203682|Planctomycetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_4873014_2	1191523.MROS_1195	8.068e-45	178.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS3_k127_4873014_0	457396.CSBG_01239	1.575e-86	309.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,36DPR@31979|Clostridiaceae	186801|Clostridia	P	potassium uptake protein, TrkH family	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS3_k127_4873014_1	760568.Desku_1250	5.168e-72	250.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS3_k127_4878409_14	1210884.HG799464_gene11139	1.116e-05	57.0	COG4105@1|root,COG4105@2|Bacteria,2J079@203682|Planctomycetes	203682|Planctomycetes	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,YfiO
CMS3_k127_4878409_10	344747.PM8797T_14229	5.176e-24	107.0	COG2980@1|root,COG2980@2|Bacteria,2J05A@203682|Planctomycetes	203682|Planctomycetes	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
CMS3_k127_4878409_0	1142394.PSMK_25340	6.465e-218	695.0	COG0465@1|root,COG0465@2|Bacteria,2IWU2@203682|Planctomycetes	203682|Planctomycetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS3_k127_4878409_9	479434.Sthe_0791	2.339e-28	123.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi,27Y78@189775|Thermomicrobia	189775|Thermomicrobia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS3_k127_4878409_4	344747.PM8797T_03414	3.498e-70	247.0	COG5012@1|root,COG5012@2|Bacteria,2IZ1E@203682|Planctomycetes	203682|Planctomycetes	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding_2,HTH_17
CMS3_k127_4878409_3	595460.RRSWK_06361	5.698e-86	295.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS3_k127_4878409_12	690850.Desaf_0357	1.281e-18	87.0	COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
CMS3_k127_4878409_11	1142394.PSMK_02970	2.555e-19	98.0	COG0568@1|root,COG0568@2|Bacteria,2IY72@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03086,ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
CMS3_k127_4878409_5	159087.Daro_1133	4.023e-59	218.0	2CD15@1|root,32RWT@2|Bacteria,1N50G@1224|Proteobacteria,2W21P@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4878409_7	1121957.ATVL01000009_gene1004	1.804e-50	187.0	COG3040@1|root,COG3040@2|Bacteria,4NNFA@976|Bacteroidetes,47R64@768503|Cytophagia	976|Bacteroidetes	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
CMS3_k127_4878409_2	344747.PM8797T_20643	3.501e-145	472.0	COG1520@1|root,COG1520@2|Bacteria,2IX2Z@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_4878409_6	1123242.JH636438_gene5714	1.421e-50	185.0	COG4276@1|root,COG4276@2|Bacteria,2J0FI@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS3_k127_4878409_13	498761.HM1_1934	2.35e-12	76.0	arCOG03622@1|root,33HZF@2|Bacteria,1VIHT@1239|Firmicutes,24QN3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4878409_8	382464.ABSI01000012_gene2192	3.694e-34	140.0	COG0702@1|root,COG0702@2|Bacteria,46WEN@74201|Verrucomicrobia,2IVZ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GM	Complex I intermediate-associated protein 30 (CIA30)	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
CMS3_k127_4878409_1	595460.RRSWK_07136	9.906e-157	509.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
CMS3_k127_4888857_0	1128421.JAGA01000004_gene2557	2.95e-200	637.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512,iYO844.BSU37780	Aldedh,Pro_dh
CMS3_k127_4888857_1	717605.Theco_2352	4.024e-38	157.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,26R7Y@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	apr	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_4902529_2	243090.RB1319	1.617e-148	492.0	COG0525@1|root,COG0525@2|Bacteria,2IWU4@203682|Planctomycetes	203682|Planctomycetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS3_k127_4902529_18	237368.SCABRO_03865	9.834e-16	86.0	arCOG12694@1|root,2ZUE6@2|Bacteria,2J46J@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4902529_1	1142394.PSMK_11160	1.363e-168	556.0	COG2217@1|root,COG2217@2|Bacteria,2IWRY@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	Band_7,E1-E2_ATPase,Hydrolase
CMS3_k127_4902529_12	63737.Npun_F4869	4.639e-30	140.0	COG2931@1|root,COG2931@2|Bacteria,1GQ21@1117|Cyanobacteria,1HJBD@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the TPP enzyme family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF3616,Exo_endo_phos,FG-GAP,HemolysinCabind,LTD
CMS3_k127_4902529_6	1267535.KB906767_gene5308	4.224e-49	187.0	COG2077@1|root,COG2077@2|Bacteria,3Y5DK@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
CMS3_k127_4902529_20	446465.Bfae_25630	0.0001865	51.0	29X98@1|root,30IYP@2|Bacteria,2HHKV@201174|Actinobacteria,4FDAX@85020|Dermabacteraceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
CMS3_k127_4902529_3	1396141.BATP01000027_gene1180	5.176e-91	322.0	COG0616@1|root,COG0616@2|Bacteria,46SQ5@74201|Verrucomicrobia,2IUT8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S49
CMS3_k127_4902529_19	1408422.JHYF01000004_gene1697	4.933e-10	71.0	COG1305@1|root,COG1305@2|Bacteria,1W0TC@1239|Firmicutes,2530S@186801|Clostridia	186801|Clostridia	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4902529_4	237368.SCABRO_03813	1.238e-66	256.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,2IXKU@203682|Planctomycetes	203682|Planctomycetes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroD	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
CMS3_k127_4902529_13	1123508.JH636439_gene1387	9.675e-29	135.0	COG0703@1|root,COG0703@2|Bacteria,2J038@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS3_k127_4902529_7	1142394.PSMK_20590	5.546e-49	184.0	2CB5F@1|root,2ZCDM@2|Bacteria,2IXTM@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4902529_15	42256.RradSPS_2116	4.121e-26	113.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS3_k127_4902529_8	1142394.PSMK_18360	1.566e-44	178.0	COG2208@1|root,COG2208@2|Bacteria,2J0ZD@203682|Planctomycetes	203682|Planctomycetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
CMS3_k127_4902529_5	309801.trd_1044	6.514e-53	191.0	COG0521@1|root,COG0521@2|Bacteria,2G6YJ@200795|Chloroflexi,27Y8Y@189775|Thermomicrobia	189775|Thermomicrobia	H	May be involved in the biosynthesis of molybdopterin	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS3_k127_4902529_9	1210884.HG799462_gene8426	8.335e-36	141.0	COG1186@1|root,COG1186@2|Bacteria,2IZSY@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
CMS3_k127_4902529_0	945713.IALB_2801	1.333e-184	587.0	COG0148@1|root,COG0148@2|Bacteria	2|Bacteria	G	phosphopyruvate hydratase activity	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS3_k127_4902529_16	1408473.JHXO01000009_gene3230	1.619e-20	99.0	290IA@1|root,2ZN74@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4902529_10	1254432.SCE1572_22375	1.254e-34	149.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4907477_2	401053.AciPR4_3251	1.085e-35	139.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_4907477_0	1122179.KB890458_gene683	1.644e-150	487.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_4907477_1	1242864.D187_001045	7.069e-71	274.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
CMS3_k127_4917415_5	1142394.PSMK_14670	1.162e-17	94.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS3_k127_4917415_2	292459.STH2487	2.017e-46	174.0	COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,24TIW@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
CMS3_k127_4917415_0	1124780.ANNU01000021_gene3017	3.216e-131	426.0	COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,47TVD@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
CMS3_k127_4917415_4	485918.Cpin_0788	5.335e-22	99.0	COG3460@1|root,COG3460@2|Bacteria,4NQFV@976|Bacteroidetes	976|Bacteroidetes	Q	Phenylacetate-CoA oxygenase	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
CMS3_k127_4917415_1	1237149.C900_04823	9.081e-70	244.0	COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,47VWV@768503|Cytophagia	976|Bacteroidetes	S	Phenylacetic acid catabolic protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
CMS3_k127_4917415_3	926560.KE387023_gene1972	6.119e-45	172.0	COG2151@1|root,COG2151@2|Bacteria,1WJW0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
CMS3_k127_4921581_0	2340.JV46_09630	5.714e-205	648.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
CMS3_k127_4921581_1	243231.GSU3248	8.666e-27	116.0	2EU5A@1|root,33MMY@2|Bacteria,1NE4I@1224|Proteobacteria,42WER@68525|delta/epsilon subdivisions,2WRAE@28221|Deltaproteobacteria,43VD3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Nitrous oxide-stimulated promoter	-	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
CMS3_k127_4922737_0	1396141.BATP01000018_gene1559	3.407e-26	111.0	COG3801@1|root,COG3801@2|Bacteria	2|Bacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS3_k127_4922737_2	1198452.Jab_1c24560	0.0003634	47.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria,47581@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
CMS3_k127_4932391_5	32049.SYNPCC7002_A1133	1.922e-59	209.0	COG1637@1|root,COG1637@2|Bacteria,1GPRG@1117|Cyanobacteria,1H3QN@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease NucS	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	NucS
CMS3_k127_4932391_2	42256.RradSPS_2487	1.983e-146	477.0	COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria	201174|Actinobacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS3_k127_4932391_3	929703.KE386491_gene2333	9.262e-89	307.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_4932391_0	1122134.KB893650_gene584	7.638e-250	788.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1XP2X@135619|Oceanospirillales	135619|Oceanospirillales	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
CMS3_k127_4932391_1	1442599.JAAN01000018_gene2871	9.71e-228	726.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RT11@1236|Gammaproteobacteria,1XCXH@135614|Xanthomonadales	135614|Xanthomonadales	EU	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_4932391_4	545695.TREAZ_3319	7.797e-76	275.0	2CFN2@1|root,34AP1@2|Bacteria,2JA1Q@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_4932391_6	234267.Acid_3759	8.329e-50	185.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	rapK	GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803	3.3.2.13,4.1.3.40,4.1.3.45	ko:K18239,ko:K18240	ko00130,ko00400,ko01100,ko01110,map00130,map00400,map01100,map01110	M00117	R01302,R10583,R10597	RC00350,RC00491,RC02148,RC03212	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribonuc_L-PSP
CMS3_k127_4940410_12	247490.KSU1_D0046	5.187e-37	148.0	COG3023@1|root,COG3023@2|Bacteria,2J0EH@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS3_k127_4940410_17	247490.KSU1_B0012	1.157e-14	83.0	COG1579@1|root,COG1579@2|Bacteria,2J0BT@203682|Planctomycetes	203682|Planctomycetes	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS3_k127_4940410_18	1142394.PSMK_14670	7.091e-11	73.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS3_k127_4940410_14	1144275.COCOR_07609	6.62e-26	119.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20,Methyltransf_25
CMS3_k127_4940410_10	886293.Sinac_6200	1.947e-50	184.0	COG0231@1|root,COG0231@2|Bacteria,2IZ4X@203682|Planctomycetes	203682|Planctomycetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS3_k127_4940410_0	1379698.RBG1_1C00001G1403	9.285e-120	411.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
CMS3_k127_4940410_21	246197.MXAN_5721	1.643e-05	49.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Excalibur,Lactamase_B
CMS3_k127_4940410_22	1123508.JH636442_gene4194	1.913e-05	54.0	2ENHC@1|root,33G4V@2|Bacteria,2J1NI@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4940410_8	243090.RB8978	1.517e-61	224.0	COG1235@1|root,COG1235@2|Bacteria,2IZQK@203682|Planctomycetes	203682|Planctomycetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_4940410_19	1210884.HG799462_gene8878	4.024e-08	66.0	29STU@1|root,30DZV@2|Bacteria,2IZET@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4940410_16	1142394.PSMK_04620	1.574e-19	105.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
CMS3_k127_4940410_7	1142394.PSMK_04470	1.588e-70	248.0	COG1611@1|root,COG1611@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS3_k127_4940410_4	1210884.HG799464_gene10601	5.911e-79	269.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS3_k127_4940410_2	373994.Riv7116_4617	8.162e-90	308.0	COG2103@1|root,COG2103@2|Bacteria,1G1DR@1117|Cyanobacteria,1HM4Y@1161|Nostocales	1117|Cyanobacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
CMS3_k127_4940410_11	1173021.ALWA01000006_gene3147	3.171e-40	164.0	COG1649@1|root,COG1649@2|Bacteria,1G2UW@1117|Cyanobacteria	1117|Cyanobacteria	NU	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS3_k127_4940410_13	1041138.KB890221_gene1413	1.192e-27	123.0	COG1940@1|root,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,2VGKA@28211|Alphaproteobacteria,4BMNN@82115|Rhizobiaceae	28211|Alphaproteobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_4940410_9	1123277.KB893172_gene951	7.374e-57	225.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_4940410_15	690850.Desaf_2163	2.995e-21	102.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS3_k127_4940410_5	690850.Desaf_2164	2.661e-78	271.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42N5I@68525|delta/epsilon subdivisions,2WM5T@28221|Deltaproteobacteria,2M9FV@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_31,Radical_SAM
CMS3_k127_4940410_1	926550.CLDAP_33840	7.099e-102	342.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_4940410_6	1210884.HG799462_gene7967	4.287e-75	256.0	COG0512@1|root,COG0512@2|Bacteria,2IYUN@203682|Planctomycetes	203682|Planctomycetes	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_4940410_3	1396141.BATP01000003_gene4876	2.241e-80	282.0	COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,2ITVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_4940410_20	1142394.PSMK_13460	6.176e-07	57.0	COG1716@1|root,COG1716@2|Bacteria,2J0SY@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS3_k127_4960580_1	1120951.AUBG01000005_gene2233	1.382e-39	153.0	COG1943@1|root,COG1943@2|Bacteria,4NPPG@976|Bacteroidetes,1IJ2E@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_4960580_0	880073.Calab_2356	1.055e-177	585.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
CMS3_k127_4960580_2	398512.JQKC01000010_gene5	1.027e-15	90.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia,3WNCH@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
CMS3_k127_4973299_2	745411.B3C1_13274	3.68e-14	86.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1R52Q@1224|Proteobacteria,1RQY5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
CMS3_k127_4973299_0	926550.CLDAP_31790	1.428e-38	164.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_22
CMS3_k127_4973299_1	382464.ABSI01000011_gene2578	1.204e-14	87.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_11,TPR_16,TPR_7,TPR_8,Trans_reg_C
CMS3_k127_4973299_3	1121920.AUAU01000010_gene25	7.994e-14	84.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
CMS3_k127_4974806_3	391596.PBAL39_01682	1.106e-30	139.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
CMS3_k127_4974806_5	530564.Psta_2883	5.551e-20	95.0	COG0848@1|root,COG0848@2|Bacteria,2J0IN@203682|Planctomycetes	203682|Planctomycetes	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_4974806_1	530564.Psta_2465	3.386e-39	160.0	COG0811@1|root,COG0811@2|Bacteria,2IZ3U@203682|Planctomycetes	203682|Planctomycetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_4974806_4	945713.IALB_1355	3.049e-22	114.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_4974806_0	1191523.MROS_0480	0.0	1030.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS3_k127_4974806_2	344747.PM8797T_31173	1.048e-36	161.0	COG4219@1|root,COG4219@2|Bacteria,2IZRJ@203682|Planctomycetes	203682|Planctomycetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS3_k127_4974806_6	1123508.JH636443_gene4729	9.253e-11	65.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_4977706_3	879212.DespoDRAFT_00387	3.071e-111	366.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,42NVQ@68525|delta/epsilon subdivisions,2WJFT@28221|Deltaproteobacteria,2MHX5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS3_k127_4977706_11	314230.DSM3645_11247	4.961e-23	109.0	2ERTX@1|root,33JD4@2|Bacteria,2J34S@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4977706_10	1123256.KB907925_gene1349	1.943e-25	117.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria,1X606@135614|Xanthomonadales	135614|Xanthomonadales	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_4977706_12	1089550.ATTH01000002_gene47	6.238e-21	94.0	COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes,1FK4T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PA26 p53-induced protein (sestrin)	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_4977706_14	309807.SRU_2769	5.808e-13	79.0	COG2128@1|root,COG2128@2|Bacteria,4NN22@976|Bacteroidetes,1FK4T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PA26 p53-induced protein (sestrin)	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_4977706_5	1123508.JH636445_gene6831	9.058e-89	302.0	COG1192@1|root,COG1192@2|Bacteria,2IX5Z@203682|Planctomycetes	203682|Planctomycetes	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_4977706_15	1122223.KB890699_gene612	2.187e-09	64.0	COG5652@1|root,COG5652@2|Bacteria,1WKND@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS3_k127_4977706_6	1210884.HG799465_gene12029	2.032e-74	258.0	COG0745@1|root,COG0745@2|Bacteria,2IZ9J@203682|Planctomycetes	203682|Planctomycetes	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_4977706_7	1123508.JH636444_gene5273	1.88e-57	224.0	COG0642@1|root,COG2205@2|Bacteria,2IZC4@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_4977706_1	1142394.PSMK_02310	4.168e-125	419.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2IY6V@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
CMS3_k127_4977706_8	1123354.AUDR01000013_gene540	1.693e-49	183.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,1KRSA@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS3_k127_4977706_0	502025.Hoch_6136	2.854e-248	778.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42Q48@68525|delta/epsilon subdivisions,2X5G4@28221|Deltaproteobacteria,2YZF5@29|Myxococcales	28221|Deltaproteobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_4977706_16	1396141.BATP01000056_gene3140	6.756e-07	62.0	COG0392@1|root,COG0392@2|Bacteria,46T31@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_4977706_13	1142394.PSMK_07340	6.536e-20	104.0	2FEU1@1|root,346SY@2|Bacteria,2J3WI@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4977706_2	1142394.PSMK_19550	1.352e-113	386.0	COG2262@1|root,COG2262@2|Bacteria,2IXH5@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS3_k127_4977706_4	1123242.JH636435_gene2149	3.288e-103	350.0	COG2208@1|root,COG2208@2|Bacteria,2IYKI@203682|Planctomycetes	203682|Planctomycetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
CMS3_k127_4977706_9	1330700.JQNC01000003_gene911	1.716e-36	147.0	COG3258@1|root,COG3258@2|Bacteria,1WMNM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_4982658_2	192952.MM_1893	6.732e-16	80.0	COG0641@1|root,arCOG00945@2157|Archaea,2Y0F7@28890|Euryarchaeota,2NAGD@224756|Methanomicrobia	224756|Methanomicrobia	K	SEC-C motif	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
CMS3_k127_4982658_3	373994.Riv7116_4073	0.0003976	51.0	COG2931@1|root,COG3266@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,1G5GU@1117|Cyanobacteria,1HMJX@1161|Nostocales	1117|Cyanobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4982658_1	1125863.JAFN01000001_gene2355	1.712e-67	250.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1PFJ7@1224|Proteobacteria,42WVE@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4982658_0	1205680.CAKO01000029_gene5109	5.318e-253	788.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2U2E4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS3_k127_4989801_0	886293.Sinac_5296	1.129e-38	154.0	COG0793@1|root,COG0793@2|Bacteria,2IX9Q@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_4989801_2	44056.XP_009035154.1	1.508e-16	94.0	KOG4287@1|root,KOG4287@2759|Eukaryota	2759|Eukaryota	M	pectin acetylesterase activity	-	-	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_4989801_1	1122612.AUBA01000018_gene2684	3.395e-30	121.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,2KEB3@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_4996768_0	767817.Desgi_3972	2.073e-210	694.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,264EG@186807|Peptococcaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_4996768_6	1125863.JAFN01000001_gene1570	5.255e-48	199.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,42S8R@68525|delta/epsilon subdivisions,2WNW6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_4996768_4	767817.Desgi_3974	1.3e-57	214.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,264MQ@186807|Peptococcaceae	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_4996768_7	1379698.RBG1_1C00001G0893	1.909e-43	167.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
CMS3_k127_4996768_2	1379698.RBG1_1C00001G0907	1.185e-135	442.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_4996768_3	269799.Gmet_2059	2.664e-106	349.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,42QAM@68525|delta/epsilon subdivisions,2WM04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_4996768_1	1379698.RBG1_1C00001G0905	4.102e-172	549.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	phaA	GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4996768_5	1125863.JAFN01000001_gene2446	4.415e-49	182.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_5003634_2	483219.LILAB_14800	2.842e-42	164.0	COG3591@1|root,COG3591@2|Bacteria,1QDPR@1224|Proteobacteria,434U5@68525|delta/epsilon subdivisions,2X90W@28221|Deltaproteobacteria,2Z1CH@29|Myxococcales	28221|Deltaproteobacteria	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_5003634_0	1123242.JH636434_gene3868	1.806e-96	334.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5003634_3	9978.XP_004592700.1	4.81e-36	153.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTVB@33213|Bilateria,4845F@7711|Chordata,48VXT@7742|Vertebrata,3JDTM@40674|Mammalia,35IJ6@314146|Euarchontoglires	33208|Metazoa	T	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	LRP6	GO:0000003,GO:0000902,GO:0000904,GO:0001101,GO:0001501,GO:0001654,GO:0001664,GO:0001667,GO:0001702,GO:0001745,GO:0001756,GO:0001763,GO:0001837,GO:0001838,GO:0001841,GO:0001843,GO:0001932,GO:0001933,GO:0001947,GO:0002009,GO:0002011,GO:0002053,GO:0002165,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003143,GO:0003306,GO:0003307,GO:0003308,GO:0003344,GO:0003401,GO:0003674,GO:0004857,GO:0004888,GO:0005041,GO:0005102,GO:0005109,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0005901,GO:0006355,GO:0006357,GO:0006469,GO:0006810,GO:0006869,GO:0006873,GO:0006874,GO:0006875,GO:0006897,GO:0006898,GO:0006928,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007204,GO:0007267,GO:0007268,GO:0007275,GO:0007350,GO:0007365,GO:0007367,GO:0007368,GO:0007369,GO:0007389,GO:0007399,GO:0007405,GO:0007417,GO:0007420,GO:0007423,GO:0007444,GO:0007447,GO:0007472,GO:0007476,GO:0007507,GO:0007548,GO:0007552,GO:0007560,GO:0007584,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008104,GO:0008150,GO:0008283,GO:0008284,GO:0008285,GO:0008587,GO:0009605,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009799,GO:0009826,GO:0009855,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009948,GO:0009950,GO:0009952,GO:0009953,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010001,GO:0010008,GO:0010033,GO:0010171,GO:0010243,GO:0010464,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010646,GO:0010647,GO:0010648,GO:0010656,GO:0010660,GO:0010720,GO:0010876,GO:0010941,GO:0010942,GO:0010975,GO:0010976,GO:0012505,GO:0014020,GO:0014029,GO:0014033,GO:0014070,GO:0015026,GO:0015850,GO:0015918,GO:0016020,GO:0016043,GO:0016049,GO:0016055,GO:0016192,GO:0016202,GO:0016331,GO:0016477,GO:0017145,GO:0017147,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019534,GO:0019725,GO:0021532,GO:0021535,GO:0021536,GO:0021537,GO:0021543,GO:0021549,GO:0021575,GO:0021587,GO:0021794,GO:0021795,GO:0021861,GO:0021872,GO:0021873,GO:0021874,GO:0021885,GO:0021903,GO:0021915,GO:0021932,GO:0021943,GO:0021953,GO:0021987,GO:0022008,GO:0022029,GO:0022037,GO:0022411,GO:0022414,GO:0022603,GO:0022610,GO:0022612,GO:0022857,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030003,GO:0030111,GO:0030154,GO:0030177,GO:0030178,GO:0030182,GO:0030228,GO:0030234,GO:0030278,GO:0030301,GO:0030326,GO:0030879,GO:0030900,GO:0030901,GO:0030902,GO:0030917,GO:0031076,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031399,GO:0031400,GO:0031410,GO:0031667,GO:0031901,GO:0031982,GO:0032268,GO:0032269,GO:0032365,GO:0032366,GO:0032367,GO:0032501,GO:0032502,GO:0032984,GO:0032989,GO:0032991,GO:0033036,GO:0033273,GO:0033673,GO:0033993,GO:0034103,GO:0034105,GO:0034185,GO:0034391,GO:0034392,GO:0034613,GO:0035050,GO:0035051,GO:0035107,GO:0035108,GO:0035112,GO:0035113,GO:0035114,GO:0035115,GO:0035116,GO:0035120,GO:0035136,GO:0035137,GO:0035148,GO:0035218,GO:0035220,GO:0035223,GO:0035239,GO:0035261,GO:0035282,GO:0035295,GO:0036314,GO:0036315,GO:0036342,GO:0036445,GO:0036477,GO:0038023,GO:0038024,GO:0040007,GO:0040011,GO:0042063,GO:0042074,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042475,GO:0042476,GO:0042493,GO:0042592,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042981,GO:0043009,GO:0043010,GO:0043025,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043235,GO:0043549,GO:0043933,GO:0044092,GO:0044093,GO:0044297,GO:0044332,GO:0044335,GO:0044340,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044853,GO:0045121,GO:0045124,GO:0045202,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045599,GO:0045664,GO:0045666,GO:0045778,GO:0045780,GO:0045787,GO:0045843,GO:0045859,GO:0045893,GO:0045935,GO:0045936,GO:0045944,GO:0045992,GO:0045995,GO:0046849,GO:0046850,GO:0046852,GO:0046907,GO:0046983,GO:0048048,GO:0048070,GO:0048073,GO:0048076,GO:0048103,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048592,GO:0048593,GO:0048596,GO:0048598,GO:0048608,GO:0048634,GO:0048635,GO:0048646,GO:0048699,GO:0048705,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048754,GO:0048762,GO:0048771,GO:0048806,GO:0048856,GO:0048863,GO:0048869,GO:0048870,GO:0048878,GO:0050678,GO:0050680,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050877,GO:0050890,GO:0050896,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051301,GO:0051338,GO:0051348,GO:0051480,GO:0051593,GO:0051641,GO:0051649,GO:0051674,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0051962,GO:0055024,GO:0055026,GO:0055057,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060019,GO:0060021,GO:0060026,GO:0060039,GO:0060041,GO:0060042,GO:0060059,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060322,GO:0060323,GO:0060324,GO:0060325,GO:0060429,GO:0060438,GO:0060439,GO:0060443,GO:0060444,GO:0060485,GO:0060534,GO:0060535,GO:0060536,GO:0060541,GO:0060548,GO:0060560,GO:0060562,GO:0060592,GO:0060596,GO:0060603,GO:0060606,GO:0060788,GO:0060828,GO:0061053,GO:0061138,GO:0061180,GO:0061307,GO:0061310,GO:0061311,GO:0061316,GO:0061324,GO:0061351,GO:0061371,GO:0061448,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071542,GO:0071696,GO:0071697,GO:0071702,GO:0071840,GO:0071900,GO:0071901,GO:0071936,GO:0071944,GO:0072089,GO:0072175,GO:0072359,GO:0072503,GO:0072507,GO:0072657,GO:0072659,GO:0080090,GO:0090009,GO:0090090,GO:0090118,GO:0090175,GO:0090178,GO:0090244,GO:0090245,GO:0090254,GO:0090263,GO:0090596,GO:0097305,GO:0097306,GO:0097458,GO:0097708,GO:0098588,GO:0098589,GO:0098590,GO:0098609,GO:0098657,GO:0098771,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120035,GO:0198738,GO:1901219,GO:1901220,GO:1901698,GO:1901700,GO:1901701,GO:1901861,GO:1901862,GO:1901963,GO:1901998,GO:1902680,GO:1903506,GO:1903508,GO:1904412,GO:1904413,GO:1904886,GO:1904928,GO:1904948,GO:1904953,GO:1905114,GO:1905276,GO:1905277,GO:1905330,GO:1905331,GO:1990778,GO:1990851,GO:1990909,GO:2000026,GO:2000027,GO:2000050,GO:2000051,GO:2000053,GO:2000055,GO:2000095,GO:2000112,GO:2000136,GO:2000148,GO:2000149,GO:2000150,GO:2000151,GO:2000159,GO:2000160,GO:2000161,GO:2000162,GO:2000163,GO:2000164,GO:2000165,GO:2000166,GO:2000167,GO:2000168,GO:2000826,GO:2001141	-	ko:K03068	ko04150,ko04310,ko05200,ko05224,ko05225,ko05226,map04150,map04310,map05200,map05224,map05225,map05226	-	-	-	ko00000,ko00001,ko04131	-	-	-	FXa_inhibition,Ldl_recept_a,Ldl_recept_b
CMS3_k127_5035823_2	1408433.JHXV01000005_gene2349	2.075e-19	102.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBIN@246874|Cryomorphaceae	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_5035823_0	391625.PPSIR1_16615	2.535e-89	305.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42S2J@68525|delta/epsilon subdivisions,2X7BN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5035823_3	96561.Dole_1274	3.952e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1RKQQ@1224|Proteobacteria,42T9T@68525|delta/epsilon subdivisions,2WPQ0@28221|Deltaproteobacteria,2MN67@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_16,TPR_2,TPR_8
CMS3_k127_5035823_1	62928.azo3723	9.403e-46	170.0	2E747@1|root,331NN@2|Bacteria,1N990@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5045278_15	263820.PTO1187	8.424e-17	86.0	COG1545@1|root,arCOG01287@2157|Archaea,2Y7AV@28890|Euryarchaeota,2427M@183967|Thermoplasmata	183967|Thermoplasmata	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_5045278_2	644282.Deba_1534	9.334e-151	489.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_5045278_0	1382306.JNIM01000001_gene2570	2.713e-259	808.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_5045278_6	983545.Glaag_1399	5.148e-79	272.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,465S5@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	liuC	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_5045278_1	1125863.JAFN01000001_gene2044	1.805e-214	686.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
CMS3_k127_5045278_7	483219.LILAB_11270	1.163e-73	275.0	COG1948@1|root,COG4880@2|Bacteria,1PQKR@1224|Proteobacteria,438JJ@68525|delta/epsilon subdivisions,2X3U8@28221|Deltaproteobacteria,2YX4D@29|Myxococcales	28221|Deltaproteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
CMS3_k127_5045278_10	1142394.PSMK_24810	3.272e-52	195.0	COG0639@1|root,COG0639@2|Bacteria,2IZ5T@203682|Planctomycetes	203682|Planctomycetes	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_5045278_9	1142394.PSMK_29780	1.824e-56	210.0	COG0515@1|root,COG0515@2|Bacteria,2IZHV@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_5045278_5	575540.Isop_2651	1.084e-106	381.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2IYMX@203682|Planctomycetes	203682|Planctomycetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
CMS3_k127_5045278_12	886293.Sinac_2598	3.507e-30	126.0	COG0745@1|root,COG0745@2|Bacteria,2IZRH@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_5045278_3	886293.Sinac_6173	2.805e-144	477.0	COG0608@1|root,COG0608@2|Bacteria,2IXVB@203682|Planctomycetes	203682|Planctomycetes	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_5045278_14	926561.KB900617_gene1818	1.077e-23	108.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3WAT3@53433|Halanaerobiales	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS3_k127_5045278_11	987059.RBXJA2T_15373	1.134e-31	144.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria,1KJ25@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Type II secretory pathway, component ExeA	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
CMS3_k127_5045278_13	1123508.JH636443_gene4909	3.434e-27	118.0	2BWMY@1|root,331GB@2|Bacteria,2J0M4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5045278_17	1250005.PHEL85_3208	5.382e-12	74.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,1I2WA@117743|Flavobacteriia,3VWJP@52959|Polaribacter	976|Bacteroidetes	M	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
CMS3_k127_5045278_8	234267.Acid_4592	3.597e-65	228.0	COG4445@1|root,COG4445@2|Bacteria,3Y8RX@57723|Acidobacteria	57723|Acidobacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CMS3_k127_5045278_4	1123508.JH636443_gene4597	9.537e-110	373.0	COG1193@1|root,COG1193@2|Bacteria,2IYIF@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	-	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
CMS3_k127_5066449_3	1397527.Q670_04045	2.571e-11	67.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SCVB@1236|Gammaproteobacteria,1XQFN@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS3_k127_5066449_5	1123242.JH636434_gene5277	0.0002641	49.0	2C4GG@1|root,331DQ@2|Bacteria,2J4JW@203682|Planctomycetes	203682|Planctomycetes	S	polyribonucleotide nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5066449_0	395965.Msil_1826	9.066e-78	291.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3NAFU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	fixL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9
CMS3_k127_5066449_1	1027273.GZ77_15620	2.422e-59	215.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1XJ7K@135619|Oceanospirillales	135619|Oceanospirillales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_5066449_6	1279015.KB908457_gene2307	0.0003758	51.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,1S9TG@1236|Gammaproteobacteria,1Y5U3@135624|Aeromonadales	135624|Aeromonadales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_5066449_2	1121468.AUBR01000026_gene2916	4.185e-14	83.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,24I2P@186801|Clostridia,42GMX@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
CMS3_k127_5066449_4	866895.HBHAL_3383	1.801e-05	51.0	2DEIG@1|root,2ZN48@2|Bacteria,1UPZ1@1239|Firmicutes,4IVDG@91061|Bacilli	91061|Bacilli	S	YjzC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YjzC
CMS3_k127_5074170_1	700598.Niako_3185	5.978e-08	66.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1J0H7@117747|Sphingobacteriia	976|Bacteroidetes	MU	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS3_k127_5074170_0	497965.Cyan7822_0583	2.528e-44	177.0	COG2931@1|root,COG3210@1|root,COG5492@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1GC1J@1117|Cyanobacteria,3KJVM@43988|Cyanothece	1117|Cyanobacteria	QU	Polymorphic membrane protein Chlamydia	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin
CMS3_k127_5096626_0	13035.Dacsa_2223	1.085e-26	128.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	fitD	-	-	ko:K19615	ko02020,map02020	-	-	-	ko00000,ko00001,ko02042	-	-	-	DUF1080,PPC,TcdA_TcdB_pore
CMS3_k127_5096626_1	339670.Bamb_2028	8.483e-06	59.0	COG3391@1|root,COG3391@2|Bacteria,1N25Z@1224|Proteobacteria,2VMGE@28216|Betaproteobacteria,1K4GK@119060|Burkholderiaceae	28216|Betaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_5119135_11	360910.BAV1268	1.6e-18	93.0	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,2VSD8@28216|Betaproteobacteria	28216|Betaproteobacteria	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_5119135_1	1121918.ARWE01000001_gene3079	7.888e-164	553.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
CMS3_k127_5119135_2	1121918.ARWE01000001_gene3080	4.194e-105	353.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales	68525|delta/epsilon subdivisions	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS3_k127_5119135_3	1121918.ARWE01000001_gene3081	3.341e-99	336.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43V7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_5119135_20	1043205.AFYF01000026_gene341	9.142e-07	56.0	COG2456@1|root,COG2456@2|Bacteria,2GQTD@201174|Actinobacteria,4FH2H@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
CMS3_k127_5119135_4	314230.DSM3645_19723	8.845e-66	235.0	COG1215@1|root,COG1215@2|Bacteria,2J52E@203682|Planctomycetes	203682|Planctomycetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5119135_15	335541.Swol_2564	1.04e-09	65.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,42K5C@68298|Syntrophomonadaceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_5119135_13	1396141.BATP01000056_gene3188	5.143e-16	84.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia,2IUPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_5119135_14	765910.MARPU_10525	2.234e-13	83.0	COG5652@1|root,COG5652@2|Bacteria,1QUYG@1224|Proteobacteria,1S55A@1236|Gammaproteobacteria,1WZAG@135613|Chromatiales	135613|Chromatiales	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS3_k127_5119135_5	330214.NIDE2776	2.645e-64	234.0	COG0604@1|root,COG0604@2|Bacteria,3J13T@40117|Nitrospirae	40117|Nitrospirae	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5119135_21	207954.MED92_05114	2.439e-05	54.0	COG2165@1|root,COG2165@2|Bacteria,1QUGH@1224|Proteobacteria,1T1Y8@1236|Gammaproteobacteria,1XM6Z@135619|Oceanospirillales	135619|Oceanospirillales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
CMS3_k127_5119135_12	1500894.JQNN01000001_gene1816	3.554e-16	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilE	-	-	ko:K02650,ko:K02655	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
CMS3_k127_5119135_9	1142394.PSMK_28050	1.931e-19	94.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CMS3_k127_5119135_17	429009.Adeg_1718	6.852e-09	67.0	COG4972@1|root,COG4972@2|Bacteria,1V19I@1239|Firmicutes,25DJ0@186801|Clostridia,42GVD@68295|Thermoanaerobacterales	186801|Clostridia	NU	Type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_5119135_6	1210884.HG799462_gene8556	1.688e-63	233.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_5119135_0	1142394.PSMK_28100	1.105e-185	597.0	COG2804@1|root,COG2804@2|Bacteria,2IX4I@203682|Planctomycetes	2|Bacteria	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_5119135_19	344747.PM8797T_09369	7.764e-07	55.0	COG1366@1|root,COG1366@2|Bacteria,2J0R5@203682|Planctomycetes	203682|Planctomycetes	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
CMS3_k127_5119135_18	438753.AZC_0741	4.515e-08	65.0	COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria,2U3QQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
CMS3_k127_5119135_7	1500894.JQNN01000001_gene1813	1.113e-52	202.0	COG2206@1|root,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,2VQE0@28216|Betaproteobacteria,476UU@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS_4
CMS3_k127_5119135_10	1211844.CBLM010000035_gene3338	3.296e-19	92.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,3VP3Q@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5119135_8	1121430.JMLG01000003_gene597	3.62e-50	197.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
CMS3_k127_5126402_1	1121289.JHVL01000016_gene698	8.484e-34	139.0	COG0793@1|root,COG0793@2|Bacteria,1V0RP@1239|Firmicutes,25D9Z@186801|Clostridia,36U8R@31979|Clostridiaceae	186801|Clostridia	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS3_k127_5126402_4	29306.JOBE01000022_gene577	6.922e-09	65.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5126402_0	314230.DSM3645_05795	4.547e-48	188.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_514504_0	880073.Calab_1549	3.627e-149	484.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS3_k127_5187352_0	880073.Calab_3115	9.522e-181	576.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	dtpD	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
CMS3_k127_5187352_3	1142394.PSMK_18750	7.294e-36	139.0	COG3118@1|root,COG3118@2|Bacteria,2J08Q@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_5187352_2	314230.DSM3645_11801	3.085e-65	239.0	COG1774@1|root,COG1774@2|Bacteria,2IWZD@203682|Planctomycetes	203682|Planctomycetes	S	signal peptidase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
CMS3_k127_5187352_4	1142394.PSMK_01480	2.09e-19	100.0	2E5IJ@1|root,3309Y@2|Bacteria,2J0P5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5187352_5	237368.SCABRO_04014	2.306e-16	82.0	COG1826@1|root,COG1826@2|Bacteria,2J1B7@203682|Planctomycetes	203682|Planctomycetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_5187352_1	880073.Calab_2044	6.868e-158	518.0	COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS3_k127_5197160_3	886293.Sinac_3947	2.999e-05	51.0	COG0457@1|root,COG0515@1|root,COG2319@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_5197160_1	1210884.HG799466_gene12935	2.803e-49	184.0	COG1595@1|root,COG1595@2|Bacteria,2J35E@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_5197160_0	696747.NIES39_Q02120	2.261e-102	364.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF5122,HemolysinCabind,Lectin_C,PPC,PQQ_2,P_proprotein,Peptidase_S8,SBBP,VCBS
CMS3_k127_5197160_2	305700.B447_00090	1.46e-12	76.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VNH0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS3_k127_52214_5	344747.PM8797T_03805	2.942e-31	132.0	COG1657@1|root,COG1657@2|Bacteria,2J0B0@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
CMS3_k127_52214_6	313606.M23134_01848	4.537e-20	106.0	COG2911@1|root,COG2911@2|Bacteria,4PKFD@976|Bacteroidetes,47S1V@768503|Cytophagia	976|Bacteroidetes	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CMS3_k127_52214_2	575540.Isop_2954	3.713e-72	253.0	COG4555@1|root,COG4555@2|Bacteria,2J504@203682|Planctomycetes	203682|Planctomycetes	CP	COG1131 ABC-type multidrug transport system ATPase component	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
CMS3_k127_52214_0	1123242.JH636435_gene2375	2.736e-78	287.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,2IXUG@203682|Planctomycetes	203682|Planctomycetes	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane_2,Abi
CMS3_k127_52214_1	589865.DaAHT2_1592	1.288e-74	256.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,42S19@68525|delta/epsilon subdivisions,2WNGU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
CMS3_k127_52214_3	1121921.KB898710_gene591	7.218e-60	223.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,2PN9B@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	M	Trypsin-like peptidase domain	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_52214_4	1380408.AVGH01000018_gene943	4.054e-40	159.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,21WJ6@150247|Anoxybacillus	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
CMS3_k127_5225581_5	298653.Franean1_1786	1.229e-15	81.0	COG2319@1|root,COG2909@1|root,COG2319@2|Bacteria,COG2909@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,NB-ARC,WD40
CMS3_k127_5225581_0	1173028.ANKO01000094_gene2595	3.359e-220	712.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H8KE@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS3_k127_5225581_2	754476.Q7A_827	3.232e-92	314.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,462GF@72273|Thiotrichales	72273|Thiotrichales	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS3_k127_5225581_1	861299.J421_5836	4.661e-170	565.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_5836|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_5225581_4	1121104.AQXH01000005_gene248	1.078e-19	91.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1IVD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS3_k127_5225581_3	1089550.ATTH01000001_gene1477	2.11e-74	273.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1FIMC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_5253270_1	530564.Psta_2724	2.579e-61	225.0	COG0265@1|root,COG0265@2|Bacteria,2IYHB@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5253270_0	530564.Psta_2725	1.343e-64	239.0	COG0265@1|root,COG0265@2|Bacteria,2IY6F@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5253270_2	1313421.JHBV01000029_gene1883	2.474e-16	94.0	COG0018@1|root,COG3210@1|root,COG0018@2|Bacteria,COG3210@2|Bacteria,4NHPN@976|Bacteroidetes,1ITWW@117747|Sphingobacteriia	976|Bacteroidetes	J	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5267206_3	313595.P700755_003488	3.829e-19	102.0	COG1073@1|root,COG2931@1|root,COG1073@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_5267206_2	1379270.AUXF01000004_gene3140	2.934e-41	170.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
CMS3_k127_5267206_0	1403819.BATR01000162_gene5395	3.619e-151	495.0	COG0457@1|root,COG0457@2|Bacteria,46W9Q@74201|Verrucomicrobia,2IVDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5267206_1	768710.DesyoDRAFT_3613	4.043e-44	166.0	COG0437@1|root,COG0437@2|Bacteria,1V4KV@1239|Firmicutes,24HGE@186801|Clostridia,263IC@186807|Peptococcaceae	186801|Clostridia	C	DMSO reductase, iron-sulfur subunit	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_3,Fer4_4
CMS3_k127_527897_5	756272.Plabr_1356	1.062e-07	55.0	COG0515@1|root,COG0515@2|Bacteria	756272.Plabr_1356|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_527897_4	382464.ABSI01000020_gene249	7.191e-09	64.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
CMS3_k127_527897_2	1469557.JSWF01000017_gene2363	1.407e-22	104.0	2ABS3@1|root,3118G@2|Bacteria,4NPFZ@976|Bacteroidetes,1I2IP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_527897_1	1479238.JQMZ01000001_gene1027	3.577e-36	147.0	COG1595@1|root,COG1595@2|Bacteria,1PBHM@1224|Proteobacteria,2UB0K@28211|Alphaproteobacteria,43YN9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_527897_3	1142394.PSMK_20550	6.341e-16	83.0	2CBRY@1|root,33DAH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_527897_0	1267535.KB906767_gene2144	7.016e-37	150.0	COG0354@1|root,COG0354@2|Bacteria,3Y2PI@57723|Acidobacteria,2JJ3H@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
CMS3_k127_5300783_0	1396141.BATP01000060_gene4560	1.459e-120	410.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CMS3_k127_5300783_4	1463820.JOGW01000007_gene1918	3.028e-15	82.0	COG1917@1|root,COG1917@2|Bacteria,2IRV4@201174|Actinobacteria	201174|Actinobacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_5300783_2	118168.MC7420_5234	7.645e-79	299.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5300783_3	1297863.APJF01000024_gene1757	9.938e-29	136.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS3_k127_5300783_1	696747.NIES39_Q02120	1.132e-91	323.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF5122,HemolysinCabind,Lectin_C,PPC,PQQ_2,P_proprotein,Peptidase_S8,SBBP,VCBS
CMS3_k127_5300783_5	1150469.RSPPHO_02781	8.17e-05	47.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5364038_4	1120951.AUBG01000011_gene2367	1.853e-28	118.0	COG3746@1|root,COG3746@2|Bacteria,4NK5I@976|Bacteroidetes,1I8DM@117743|Flavobacteriia	976|Bacteroidetes	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS3_k127_5364038_2	309801.trd_1832	7.829e-99	334.0	COG0226@1|root,COG0226@2|Bacteria,2GAAI@200795|Chloroflexi,27YVN@189775|Thermomicrobia	189775|Thermomicrobia	P	Phosphate ABC transporter, periplasmic phosphate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_5364038_1	743719.PaelaDRAFT_0241	1.698e-99	333.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,26SNZ@186822|Paenibacillaceae	91061|Bacilli	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS3_k127_5364038_3	518766.Rmar_1827	3.45e-97	332.0	COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1FIYE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS3_k127_5364038_0	1469607.KK073769_gene6219	7.413e-106	352.0	COG1117@1|root,COG1117@2|Bacteria,1G0P6@1117|Cyanobacteria,1HIVS@1161|Nostocales	1117|Cyanobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS3_k127_5364038_5	1265505.ATUG01000001_gene3916	4.543e-21	99.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2MICR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS3_k127_5387151_0	1379698.RBG1_1C00001G1403	1.001e-108	399.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
CMS3_k127_5387151_2	1330700.JQNC01000003_gene911	3.278e-37	164.0	COG3258@1|root,COG3258@2|Bacteria,1WMNM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_5387151_3	72019.SARC_11747T0	3.154e-11	77.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta	33154|Opisthokonta	T	calcium ion binding	-	-	-	ko:K02599	ko01522,ko04320,ko04330,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002	-	-	-	EGF,SRCR,hEGF
CMS3_k127_5387151_5	148304.MAPG_00100T0	1.803e-05	58.0	292CQ@1|root,2R994@2759|Eukaryota,38M38@33154|Opisthokonta,3PNZM@4751|Fungi,3R882@4890|Ascomycota,21EKA@147550|Sordariomycetes,41QDK@639021|Magnaporthales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5387151_1	526225.Gobs_1200	1.019e-37	156.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	3.4.21.7	ko:K01315	ko04080,ko04610,ko05150,ko05164,map04080,map04610,map05150,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147,ko04516	-	-	-	PPC,Trypsin_2
CMS3_k127_5389315_9	1123508.JH636442_gene4175	9.142e-37	140.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2IY5P@203682|Planctomycetes	203682|Planctomycetes	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_5389315_1	443143.GM18_1943	2.805e-138	446.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,43SIZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	uxs	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_5389315_3	330214.NIDE3417	1.7e-111	373.0	COG0399@1|root,COG0399@2|Bacteria,3J09X@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_5389315_6	590998.Celf_0721	3.822e-50	203.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4F2TG@85016|Cellulomonadaceae	201174|Actinobacteria	M	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA,Wzz
CMS3_k127_5389315_8	1142394.PSMK_22340	2.312e-38	156.0	COG1269@1|root,COG1269@2|Bacteria,2IZU8@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS3_k127_5389315_7	1142394.PSMK_22330	1.274e-43	178.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS3_k127_5389315_2	338963.Pcar_1613	3.079e-135	443.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS3_k127_5389315_5	237368.SCABRO_01544	3.154e-61	229.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS3_k127_5389315_0	314230.DSM3645_01871	1.537e-292	915.0	COG0243@1|root,COG0243@2|Bacteria,2IXVV@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
CMS3_k127_5389315_4	28072.Nos7524_2690	1.079e-83	288.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1HK26@1161|Nostocales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS3_k127_5389315_10	58344.JOEL01000053_gene3423	3.004e-27	120.0	COG0662@1|root,COG0662@2|Bacteria,2IHNU@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_5389315_11	929556.Solca_2525	9.55e-20	98.0	COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,1IPGU@117747|Sphingobacteriia	976|Bacteroidetes	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_5420215_3	1297742.A176_02258	5.473e-53	193.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_5420215_4	1396.DJ87_1768	1.089e-08	63.0	2EUXT@1|root,33ND3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3841
CMS3_k127_5420215_0	756272.Plabr_2304	4.008e-221	725.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2IYHP@203682|Planctomycetes	203682|Planctomycetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_5420215_2	1123508.JH636440_gene2104	1.625e-72	251.0	COG1136@1|root,COG1136@2|Bacteria,2IZ2X@203682|Planctomycetes	203682|Planctomycetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
CMS3_k127_5420215_1	314230.DSM3645_13770	6.115e-98	338.0	COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_5420582_2	861299.J421_1034	4.662e-13	70.0	COG1595@1|root,COG1595@2|Bacteria,1ZV2D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_5420582_3	985867.AEWF01000003_gene758	2.713e-11	79.0	COG2133@1|root,COG3210@1|root,COG4625@1|root,COG2133@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	ko:K19231	-	-	-	-	ko00000,ko02000	1.B.12	-	-	Autotransporter,NHL,PATR,Peptidase_M10_C
CMS3_k127_5420582_0	391625.PPSIR1_35712	0.0	1297.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_5420582_1	1121920.AUAU01000014_gene2803	3.98e-120	392.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_5467053_2	316274.Haur_1194	2.83e-35	138.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,376AI@32061|Chloroflexia	32061|Chloroflexia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_5467053_4	929712.KI912613_gene3922	0.0009023	53.0	COG1520@1|root,COG1520@2|Bacteria,2HF4U@201174|Actinobacteria,4CPDR@84995|Rubrobacteria	84995|Rubrobacteria	S	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_5467053_3	1123508.JH636440_gene2792	4.847e-14	87.0	COG1520@1|root,COG1520@2|Bacteria,2IZ2Z@203682|Planctomycetes	203682|Planctomycetes	H	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,TPR_6
CMS3_k127_5467053_0	215803.DB30_2732	1.007e-86	295.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria,2YX9V@29|Myxococcales	28221|Deltaproteobacteria	F	Purine nucleoside phosphorylase involved in purine salvage	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_5467053_1	883.DvMF_2659	3.782e-60	214.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_5485030_1	1352941.M877_28790	1.366e-23	102.0	2AYWB@1|root,31R1X@2|Bacteria,2IMVA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5485030_2	1079986.JH164837_gene5804	7.191e-09	64.0	2B0T4@1|root,31T5H@2|Bacteria,2GRT6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5485030_0	208439.AJAP_28110	4.976e-105	349.0	COG4653@1|root,COG4653@2|Bacteria,2I9E6@201174|Actinobacteria,4E52K@85010|Pseudonocardiales	201174|Actinobacteria	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
CMS3_k127_5495578_8	1128427.KB904821_gene3775	2.16e-70	245.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1H8MW@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS3_k127_5495578_11	215803.DB30_5251	2.329e-44	173.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1RGUX@1224|Proteobacteria,437BZ@68525|delta/epsilon subdivisions,2WQNB@28221|Deltaproteobacteria,2YVJC@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS3_k127_5495578_18	314230.DSM3645_05959	1.561e-11	74.0	COG2318@1|root,COG2318@2|Bacteria,2J061@203682|Planctomycetes	203682|Planctomycetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_5495578_2	316274.Haur_0326	2.333e-107	359.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,374U8@32061|Chloroflexia	32061|Chloroflexia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS3_k127_5495578_9	1267534.KB906755_gene4692	9.512e-65	244.0	COG0642@1|root,COG2205@2|Bacteria	1267534.KB906755_gene4692|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5495578_7	1267534.KB906755_gene4691	3.713e-71	247.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria	57723|Acidobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5495578_13	1509403.GW12_01390	3.996e-28	119.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria,3NNMS@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_5495578_12	1042877.GQS_05030	1.512e-37	147.0	COG0622@1|root,arCOG01141@2157|Archaea,2XX8V@28890|Euryarchaeota,2430D@183968|Thermococci	183968|Thermococci	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS3_k127_5495578_14	243090.RB10069	1.184e-25	112.0	2DVHI@1|root,32UZG@2|Bacteria,2J0QY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_5495578_10	997346.HMPREF9374_2238	1.218e-58	220.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,27BN4@186824|Thermoactinomycetaceae	91061|Bacilli	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_5495578_1	521674.Plim_2827	1.836e-113	385.0	COG0111@1|root,COG0111@2|Bacteria,2IWX7@203682|Planctomycetes	203682|Planctomycetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_5495578_6	1499967.BAYZ01000151_gene1675	4.48e-76	264.0	COG1355@1|root,COG1355@2|Bacteria,2NQ00@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS3_k127_5495578_17	1382359.JIAL01000001_gene1562	1.869e-16	85.0	29ITM@1|root,305QZ@2|Bacteria,3Y4F3@57723|Acidobacteria,2JJ2C@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5495578_16	379066.GAU_0906	1.059e-16	88.0	COG2839@1|root,COG2839@2|Bacteria,1ZUVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
CMS3_k127_5495578_0	272568.GDI0241	1.744e-182	591.0	COG0021@1|root,COG0021@2|Bacteria,1QYA4@1224|Proteobacteria,2TXK4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	XFP N-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS3_k127_5495578_5	358681.BBR47_50010	6.287e-79	274.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,26UEW@186822|Paenibacillaceae	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_5495578_4	867903.ThesuDRAFT_01465	1.54e-88	304.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3WCJ4@538999|Clostridiales incertae sedis	186801|Clostridia	I	PFAM Enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_5495578_3	1121090.KB894700_gene3295	3.199e-105	349.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4IU6J@91061|Bacilli	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
CMS3_k127_5495578_15	243090.RB11207	1.799e-25	113.0	COG0398@1|root,COG0398@2|Bacteria,2J2ZN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547,SNARE_assoc
CMS3_k127_55060_0	886293.Sinac_3618	1.62e-111	400.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_55060_1	886293.Sinac_4026	3.49e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_55060_3	203122.Sde_2049	4.728e-12	81.0	COG5184@1|root,COG5276@1|root,COG5644@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5644@2|Bacteria,1QX03@1224|Proteobacteria,1T31Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
CMS3_k127_55060_4	1194165.CAJF01000012_gene984	5.051e-10	74.0	COG2374@1|root,COG2374@2|Bacteria,2I2E0@201174|Actinobacteria,4FTPB@85023|Microbacteriaceae	201174|Actinobacteria	M	endonuclease exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Big_3_5,Big_5,CW_binding_2,DUF3616,Exo_endo_phos,LTD
CMS3_k127_55060_2	1121377.KB906434_gene693	3.384e-52	214.0	COG2885@1|root,COG4386@1|root,COG2885@2|Bacteria,COG4386@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K16191,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.6.1.3	-	-	Big_3_2,CHU_C,Calx-beta,DUF11,OmpA
CMS3_k127_55060_5	313595.P700755_003488	5.52e-08	63.0	COG1073@1|root,COG2931@1|root,COG1073@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_5531430_0	1120977.JHUX01000003_gene704	7.667e-05	54.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,3NKBN@468|Moraxellaceae	1236|Gammaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS3_k127_5531430_1	631454.N177_1596	0.0001582	52.0	COG2846@1|root,COG2846@2|Bacteria,1RKE4@1224|Proteobacteria,2U9WK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_5531430_2	1205680.CAKO01000002_gene2743	0.0004226	45.0	COG3861@1|root,COG3861@2|Bacteria,1N3JG@1224|Proteobacteria,2UH3C@28211|Alphaproteobacteria,2JTXV@204441|Rhodospirillales	204441|Rhodospirillales	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
CMS3_k127_5536622_3	1499967.BAYZ01000024_gene282	9.319e-35	155.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	Otg1	-	-	-	-	-	-	-	-	-	-	-	DUF2339,DUF4167
CMS3_k127_5536622_1	1210884.HG799469_gene14163	9.712e-136	447.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_5536622_0	1210884.HG799469_gene14163	1.715e-139	459.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_5536622_5	1192034.CAP_0825	3.45e-21	109.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5536622_2	760192.Halhy_5729	1.469e-42	177.0	COG1404@1|root,COG3209@1|root,COG3210@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,4P8KP@976|Bacteroidetes,1IYSQ@117747|Sphingobacteriia	976|Bacteroidetes	U	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	SprB
CMS3_k127_5536622_6	234267.Acid_1108	8.322e-12	71.0	COG0666@1|root,COG1657@1|root,COG0666@2|Bacteria,COG1657@2|Bacteria,3Y83C@57723|Acidobacteria	2|Bacteria	I	Ankyrin repeats (many copies)	-	-	3.5.1.81	ko:K06015,ko:K06867,ko:K06886	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,Prenyltrans,SQHop_cyclase_C,YkuD
CMS3_k127_5536622_4	1266925.JHVX01000025_gene1542	2.205e-22	107.0	COG0737@1|root,COG0737@2|Bacteria,1RFNB@1224|Proteobacteria,2VR8M@28216|Betaproteobacteria,372HK@32003|Nitrosomonadales	28216|Betaproteobacteria	C	to Cytochrome c-554 precursor (C554) (Hydroxylamine oxidoreductase-linked cytochrome) pir A59036 cytochrome c554, tetraheme, precursor - Nitrosomonas europaea	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_5536622_7	391625.PPSIR1_00450	4.557e-11	75.0	COG3147@1|root,COG3147@2|Bacteria	2|Bacteria	S	peptidoglycan binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4082,Rib
CMS3_k127_5536622_10	1324957.K933_02471	0.0001817	53.0	COG3794@1|root,arCOG02919@2157|Archaea,2XUJM@28890|Euryarchaeota,23TSS@183963|Halobacteria	183963|Halobacteria	C	COG3794 Plastocyanin	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,DUF5059
CMS3_k127_5536622_8	1455608.JDTH01000002_gene1046	6.745e-07	57.0	COG3794@1|root,arCOG02920@2157|Archaea,2Y7VI@28890|Euryarchaeota,23VT8@183963|Halobacteria	183963|Halobacteria	C	COG3794 Plastocyanin	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_5540420_6	1367847.JCM7686_3000	1.82e-06	59.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,2PW3Q@265|Paracoccus	28211|Alphaproteobacteria	O	PPIC-type PPIASE domain	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
CMS3_k127_5540420_5	521674.Plim_0733	6.868e-46	173.0	COG0563@1|root,COG0563@2|Bacteria,2IZRF@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
CMS3_k127_5540420_1	886293.Sinac_7456	1.05e-73	258.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_5540420_0	243231.GSU0686	1.006e-181	590.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS3_k127_5540420_3	330214.NIDE2456	1.486e-51	193.0	COG0061@1|root,COG0061@2|Bacteria,3J0HS@40117|Nitrospirae	40117|Nitrospirae	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS3_k127_5540420_4	439235.Dalk_3808	2.962e-51	197.0	COG0760@1|root,COG0760@2|Bacteria,1PK24@1224|Proteobacteria,43A0E@68525|delta/epsilon subdivisions,2X9PT@28221|Deltaproteobacteria,2MP0Y@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
CMS3_k127_5540420_2	1121413.JMKT01000013_gene985	2.627e-62	219.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42PMA@68525|delta/epsilon subdivisions,2X5AR@28221|Deltaproteobacteria,2MGNP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
CMS3_k127_556789_13	756272.Plabr_3829	1.884e-42	160.0	COG0537@1|root,COG0537@2|Bacteria,2IZTG@203682|Planctomycetes	203682|Planctomycetes	FG	COGs COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
CMS3_k127_556789_4	751945.Theos_0668	3.809e-86	297.0	COG0232@1|root,COG0232@2|Bacteria,1WI39@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the dGTPase family. Type 2 subfamily	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS3_k127_556789_16	886293.Sinac_2273	2.232e-33	137.0	COG0220@1|root,COG0220@2|Bacteria,2IZJM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS3_k127_556789_5	398512.JQKC01000030_gene4396	1.065e-84	291.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,3WHWU@541000|Ruminococcaceae	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS3_k127_556789_11	1123508.JH636441_gene3274	5.911e-61	230.0	COG0063@1|root,COG0063@2|Bacteria,2IYWH@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
CMS3_k127_556789_6	1379698.RBG1_1C00001G1502	1.316e-77	273.0	COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_556789_19	1123325.JHUV01000010_gene1231	8.954e-06	52.0	COG4783@1|root,COG4783@2|Bacteria,2G573@200783|Aquificae	200783|Aquificae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS3_k127_556789_1	530564.Psta_3018	6.484e-110	369.0	COG1260@1|root,COG1260@2|Bacteria,2IWUF@203682|Planctomycetes	203682|Planctomycetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
CMS3_k127_556789_3	886293.Sinac_1752	1.071e-97	327.0	COG1082@1|root,COG1082@2|Bacteria,2IZG2@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_556789_15	1132509.C447_10855	7.923e-35	145.0	COG0382@1|root,arCOG00476@2157|Archaea,2XVWN@28890|Euryarchaeota,23UXI@183963|Halobacteria	183963|Halobacteria	H	COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_556789_12	525904.Tter_2202	2.234e-57	218.0	COG0153@1|root,COG0153@2|Bacteria,2NQRK@2323|unclassified Bacteria	2|Bacteria	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS3_k127_556789_14	237368.SCABRO_03862	2.13e-35	139.0	COG1259@1|root,COG1259@2|Bacteria,2IZNE@203682|Planctomycetes	203682|Planctomycetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS3_k127_556789_7	429009.Adeg_1877	8.607e-77	269.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42FEE@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS3_k127_556789_9	1382356.JQMP01000001_gene827	6.509e-68	246.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_556789_17	706587.Desti_1240	1.794e-26	124.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria,1QSA7@1224|Proteobacteria,42T4Y@68525|delta/epsilon subdivisions,2WPNT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol disulfide interchange protein dsbA	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4,VKOR
CMS3_k127_556789_10	765910.MARPU_14455	8.137e-67	250.0	COG3379@1|root,COG3379@2|Bacteria,1PWC6@1224|Proteobacteria,1TKB0@1236|Gammaproteobacteria,1X1DI@135613|Chromatiales	135613|Chromatiales	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_556789_2	1210884.HG799462_gene7991	2.006e-101	336.0	COG1351@1|root,COG1351@2|Bacteria,2J0W9@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	-	-	-	-	-	-	-	-	-	-	Thy1
CMS3_k127_556789_0	221288.JH992901_gene3451	8.581e-144	473.0	COG0160@1|root,COG0160@2|Bacteria,1G26B@1117|Cyanobacteria,1JGWA@1189|Stigonemataceae	1117|Cyanobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_556789_18	886379.AEWI01000027_gene411	1.192e-15	84.0	COG4747@1|root,COG4747@2|Bacteria,4NQIW@976|Bacteroidetes,2FS2U@200643|Bacteroidia,3XK6D@558415|Marinilabiliaceae	976|Bacteroidetes	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
CMS3_k127_556789_8	243231.GSU1088	9.126e-77	276.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CMS3_k127_5592432_1	344747.PM8797T_08314	7.635e-12	68.0	COG1595@1|root,COG1595@2|Bacteria,2J539@203682|Planctomycetes	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4179,OMP_b-brl,OMP_b-brl_2
CMS3_k127_5592432_0	1417296.U879_21490	2.829e-72	263.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_5659222_0	441620.Mpop_2367	1.164e-73	255.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2U2IQ@28211|Alphaproteobacteria,1JSNQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM SapC family protein	-	-	-	-	-	-	-	-	-	-	-	-	SapC
CMS3_k127_5659222_2	1121479.AUBS01000031_gene105	2.891e-30	143.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS3_k127_5659222_3	768671.ThimaDRAFT_4036	2.456e-26	130.0	COG3291@1|root,COG3291@2|Bacteria,1R0I3@1224|Proteobacteria,1SE92@1236|Gammaproteobacteria,1X0E9@135613|Chromatiales	135613|Chromatiales	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS3_k127_5659222_4	765912.Thimo_3087	2.595e-24	123.0	COG3291@1|root,COG3291@2|Bacteria,1R0I3@1224|Proteobacteria,1SE92@1236|Gammaproteobacteria,1X0E9@135613|Chromatiales	135613|Chromatiales	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS3_k127_5659222_1	272134.KB731324_gene890	3.167e-56	229.0	COG2931@1|root,COG3210@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G0DX@1117|Cyanobacteria,1H9Z9@1150|Oscillatoriales	1117|Cyanobacteria	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Calx-beta,DUF11,DUF4347,HemolysinCabind,Laminin_G_3,VCBS
CMS3_k127_5674083_0	314230.DSM3645_12111	3.612e-142	474.0	COG1413@1|root,COG3303@1|root,COG1413@2|Bacteria,COG3303@2|Bacteria,2J0SN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_5674083_1	344747.PM8797T_23781	2.994e-83	283.0	COG0854@1|root,COG0854@2|Bacteria,2IYJ4@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS3_k127_5674083_2	886293.Sinac_5594	7.85e-76	265.0	COG0329@1|root,COG0329@2|Bacteria,2IXII@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS3_k127_5674083_4	1142394.PSMK_18550	5.149e-45	177.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2J0C4@203682|Planctomycetes	203682|Planctomycetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
CMS3_k127_5674083_7	926550.CLDAP_13520	7.939e-15	81.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5674083_6	926550.CLDAP_13510	1.176e-20	94.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5674083_3	945713.IALB_0547	4.622e-54	194.0	COG2406@1|root,COG2406@2|Bacteria	2|Bacteria	S	Ferritin, Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS3_k127_5679466_12	497964.CfE428DRAFT_0306	4.927e-13	80.0	COG2165@1|root,COG2165@2|Bacteria,46WQM@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS3_k127_5679466_11	314230.DSM3645_08702	2.168e-20	97.0	COG0622@1|root,COG0622@2|Bacteria,2J04S@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS3_k127_5679466_5	886293.Sinac_3912	1.666e-67	245.0	COG0463@1|root,COG0463@2|Bacteria,2IZV0@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5679466_10	675635.Psed_5156	1.584e-29	125.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DXKC@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5679466_13	1366050.N234_19340	0.0008049	50.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria,1JZU9@119060|Burkholderiaceae	28216|Betaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	prtR	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_5679466_6	589865.DaAHT2_1074	1.224e-51	194.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2MIK9@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
CMS3_k127_5679466_4	35754.JNYJ01000001_gene7308	1.086e-72	261.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4DA75@85008|Micromonosporales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5679466_1	1297742.A176_03139	1.058e-122	407.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5679466_2	1211814.CAPG01000064_gene3030	7.087e-121	399.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5679466_3	479434.Sthe_1202	5.471e-99	331.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_5679466_8	869210.Marky_0923	2.299e-42	166.0	COG1024@1|root,COG1024@2|Bacteria,1WIJM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_5679466_0	880073.Calab_3014	1.08e-203	647.0	COG1884@1|root,COG1884@2|Bacteria,2NNZ9@2323|unclassified Bacteria	2|Bacteria	I	Methylmalonyl-CoA mutase	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS3_k127_5679466_7	1869.MB27_13675	3.975e-51	201.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4DAMM@85008|Micromonosporales	201174|Actinobacteria	E	Lao ao transport system	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_5679466_9	1403819.BATR01000005_gene144	9.967e-35	136.0	COG1573@1|root,COG1573@2|Bacteria,46UE4@74201|Verrucomicrobia,2ITSY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	uracil-dna glycosylase	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_5736674_4	1208321.D104_07150	2.031e-33	131.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,1XHEZ@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS3_k127_5736674_2	309807.SRU_2799	2.013e-90	311.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_5736674_0	941449.dsx2_3431	1.656e-181	575.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2M9RZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_5736674_5	243231.GSU3225	5.623e-28	126.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,43AJ0@68525|delta/epsilon subdivisions,2X5Z8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5736674_7	1167006.UWK_00561	4.615e-18	94.0	COG3303@1|root,COG3303@2|Bacteria,1NX4E@1224|Proteobacteria,431QJ@68525|delta/epsilon subdivisions,2WWSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_5736674_1	880073.Calab_1263	9.813e-155	510.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_5736674_3	443144.GM21_3109	2.718e-51	195.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,43AJ0@68525|delta/epsilon subdivisions,2X5Z8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_5736674_8	1167006.UWK_00564	7.509e-18	98.0	2ENA5@1|root,33FXV@2|Bacteria,1P5GM@1224|Proteobacteria,432FV@68525|delta/epsilon subdivisions,2WX6T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5736674_6	880073.Calab_1269	8.66e-20	96.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_5736674_9	1535422.ND16A_0736	1.584e-16	87.0	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_5755059_0	2045.KR76_19110	1.113e-07	63.0	COG4625@1|root,COG4625@2|Bacteria,2GY9J@201174|Actinobacteria,4DW2W@85009|Propionibacteriales	201174|Actinobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5770532_4	1238450.VIBNISOn1_450132	3.75e-14	79.0	COG0454@1|root,COG0456@2|Bacteria,1RIU4@1224|Proteobacteria,1S6NR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_5770532_2	1142394.PSMK_03380	1.105e-43	170.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_5770532_0	1123508.JH636444_gene5262	9.846e-96	326.0	COG0809@1|root,COG0809@2|Bacteria,2IWS2@203682|Planctomycetes	203682|Planctomycetes	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS3_k127_5770532_1	1142394.PSMK_14770	1.234e-68	248.0	COG1560@1|root,COG1560@2|Bacteria,2IY7N@203682|Planctomycetes	203682|Planctomycetes	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_5770532_3	311424.DhcVS_204	5.107e-18	93.0	COG2314@1|root,COG2314@2|Bacteria,2GAV8@200795|Chloroflexi,34DEZ@301297|Dehalococcoidia	301297|Dehalococcoidia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2,zinc_ribbon_2
CMS3_k127_5770532_5	5762.XP_002670031.1	3.953e-06	59.0	2EUNG@1|root,2SWSM@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5774414_1	886293.Sinac_5114	4.617e-125	415.0	COG0182@1|root,COG0182@2|Bacteria,2IWRJ@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS3_k127_5774414_3	537013.CLOSTMETH_00273	7.588e-41	158.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS3_k127_5774414_4	344747.PM8797T_22478	1.623e-35	139.0	2D5DF@1|root,32TIU@2|Bacteria,2J0DN@203682|Planctomycetes	203682|Planctomycetes	S	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
CMS3_k127_5774414_2	1166018.FAES_1988	1.036e-113	382.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47M3Z@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_5774414_0	521674.Plim_1325	0.0	1055.0	COG0587@1|root,COG0587@2|Bacteria,2IWSE@203682|Planctomycetes	203682|Planctomycetes	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
CMS3_k127_5774414_5	402881.Plav_2530	1.162e-23	104.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,1JNI9@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C
CMS3_k127_5782645_1	1142394.PSMK_02370	3.575e-40	154.0	COG2928@1|root,COG2928@2|Bacteria,2IZGR@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS3_k127_5782645_4	236097.ADG881_2891	1.023e-18	89.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1XKFR@135619|Oceanospirillales	135619|Oceanospirillales	J	seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS3_k127_5782645_2	886293.Sinac_3263	1.151e-38	151.0	COG1762@1|root,COG1762@2|Bacteria,2IZ73@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
CMS3_k127_5782645_5	1142394.PSMK_30770	9.435e-14	75.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	2.7.1.121	ko:K05881,ko:K11189	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	4.A.2.1	-	-	EIIA-man,PTS-HPr
CMS3_k127_5782645_0	243090.RB8591	5.809e-144	479.0	COG1080@1|root,COG1080@2|Bacteria,2IX08@203682|Planctomycetes	203682|Planctomycetes	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
CMS3_k127_5782645_3	555088.DealDRAFT_1012	8e-23	107.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,42K67@68298|Syntrophomonadaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
CMS3_k127_5790996_8	1111732.AZOD01000011_gene547	2.275e-30	129.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1X3MH@135614|Xanthomonadales	135614|Xanthomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_5790996_7	1123508.JH636439_gene1032	2.597e-53	198.0	COG0688@1|root,COG0688@2|Bacteria,2IXE7@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS3_k127_5790996_11	1227484.C471_15652	1.756e-10	69.0	COG3794@1|root,arCOG02921@2157|Archaea,2XZ0D@28890|Euryarchaeota,23WZS@183963|Halobacteria	183963|Halobacteria	C	COG3794 Plastocyanin	hcp1	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,TAT_signal
CMS3_k127_5790996_2	583355.Caka_0857	2.343e-100	346.0	COG0591@1|root,COG0591@2|Bacteria,46ZB9@74201|Verrucomicrobia,3K8WD@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_5790996_4	1280680.AUJU01000028_gene3310	2.009e-74	276.0	COG3525@1|root,COG3525@2|Bacteria,1TSXM@1239|Firmicutes,248U1@186801|Clostridia,4BYQY@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
CMS3_k127_5790996_9	1280676.AUJO01000020_gene3310	1.341e-24	117.0	COG0726@1|root,COG0726@2|Bacteria,1UZY2@1239|Firmicutes,25PWG@186801|Clostridia,4C0YE@830|Butyrivibrio	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_5790996_1	1123242.JH636435_gene1911	2.621e-207	666.0	COG0210@1|root,COG0210@2|Bacteria,2IY8S@203682|Planctomycetes	203682|Planctomycetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_5790996_0	1173026.Glo7428_0294	2.463e-216	690.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_5790996_14	1122138.AQUZ01000001_gene1557	8.595e-06	55.0	2DMKY@1|root,32SAM@2|Bacteria,2IR8I@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5790996_12	713587.THITH_07395	1.408e-09	69.0	COG3386@1|root,COG3386@2|Bacteria,1NFEJ@1224|Proteobacteria	1224|Proteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5790996_5	713586.KB900536_gene1765	3.986e-69	246.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales	135613|Chromatiales	O	heat shock protein DnaJ	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS3_k127_5790996_6	1485544.JQKP01000002_gene1396	5.158e-54	199.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,44VK9@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_5790996_10	292415.Tbd_2497	1.872e-23	111.0	COG1493@1|root,COG1493@2|Bacteria,1QWDD@1224|Proteobacteria,2WH4H@28216|Betaproteobacteria,1KS72@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5790996_16	1198114.AciX9_2169	0.0005852	48.0	28UBM@1|root,2ZGH0@2|Bacteria	2|Bacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
CMS3_k127_5790996_15	572477.Alvin_2117	5.26e-05	55.0	COG2940@1|root,COG2940@2|Bacteria,1N2WJ@1224|Proteobacteria,1TJR6@1236|Gammaproteobacteria,1WYYZ@135613|Chromatiales	135613|Chromatiales	S	pfam set	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
CMS3_k127_5790996_13	1248760.ANFZ01000014_gene2135	2.433e-06	60.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS3_k127_5790996_3	886293.Sinac_5248	1.391e-84	302.0	COG2804@1|root,COG2804@2|Bacteria,2IXVD@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE
CMS3_k127_5811193_3	234267.Acid_5749	5.297e-07	56.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_5811193_1	234267.Acid_5749	2.599e-193	634.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_5811193_2	1121033.AUCF01000010_gene4432	1.055e-13	85.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,2UA53@28211|Alphaproteobacteria,2JWXG@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_5811193_0	1535422.ND16A_2150	3.012e-249	795.0	COG3485@1|root,COG4932@1|root,COG5276@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,CarboxypepD_reg,DUF11,FG-GAP
CMS3_k127_5827918_0	1500301.JQMF01000010_gene2077	6.137e-28	122.0	COG0666@1|root,COG3474@1|root,COG0666@2|Bacteria,COG3474@2|Bacteria,1PQVQ@1224|Proteobacteria,2V37E@28211|Alphaproteobacteria,4BK96@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5827918_1	1502851.FG93_00324	7.425e-24	112.0	COG0412@1|root,COG0412@2|Bacteria,1R5J6@1224|Proteobacteria,2UE6V@28211|Alphaproteobacteria,3JVDW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
CMS3_k127_5827918_2	565045.NOR51B_1704	0.0001312	47.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1J5XY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Oxygen tolerance	batD	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS3_k127_5856334_6	525904.Tter_2057	2.421e-76	267.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	MA20_14995	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_5856334_15	637389.Acaty_c1652	2.211e-17	86.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,2ND44@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS3_k127_5856334_7	1142394.PSMK_16480	2.543e-69	249.0	COG0202@1|root,COG0457@1|root,COG0202@2|Bacteria,COG0457@2|Bacteria,2IXMK@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase alpha	-	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,TPR_1,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
CMS3_k127_5856334_11	207559.Dde_1785	3.499e-33	144.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2MAVE@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID,TPR_6,TPR_8
CMS3_k127_5856334_9	530564.Psta_4651	2.126e-65	239.0	COG1482@1|root,COG1482@2|Bacteria,2IZ3A@203682|Planctomycetes	203682|Planctomycetes	G	mannose-6-phosphate isomerase	pmi	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS3_k127_5856334_12	246969.TAM4_1724	3.234e-31	126.0	COG0143@1|root,arCOG00810@2157|Archaea,2XTG5@28890|Euryarchaeota,242K4@183968|Thermococci	183968|Thermococci	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS3_k127_5856334_10	1123508.JH636443_gene4721	7.25e-64	230.0	COG2890@1|root,COG2890@2|Bacteria,2IYX6@203682|Planctomycetes	203682|Planctomycetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
CMS3_k127_5856334_2	344747.PM8797T_26045	5.173e-144	470.0	COG0766@1|root,COG0766@2|Bacteria,2IWRI@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS3_k127_5856334_19	429009.Adeg_1274	1.065e-05	52.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,42H3I@68295|Thermoanaerobacterales	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS3_k127_5856334_3	886293.Sinac_5631	9.776e-136	448.0	COG0343@1|root,COG0343@2|Bacteria,2IWXI@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS3_k127_5856334_20	2045.KR76_01515	1.705e-05	57.0	COG1807@1|root,COG1807@2|Bacteria,2HZ7H@201174|Actinobacteria,4DQHP@85009|Propionibacteriales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5856334_14	667014.Thein_2200	1.334e-19	98.0	COG0603@1|root,COG0603@2|Bacteria,2GHPZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS3_k127_5856334_8	886293.Sinac_1570	5.744e-69	249.0	COG4198@1|root,COG4198@2|Bacteria,2IX7C@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CMS3_k127_5856334_13	1125863.JAFN01000001_gene2857	2.207e-29	133.0	COG3391@1|root,COG3391@2|Bacteria,1RJQF@1224|Proteobacteria,42VW9@68525|delta/epsilon subdivisions,2WRUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5856334_0	1142394.PSMK_21320	1.409e-230	741.0	COG0187@1|root,COG0187@2|Bacteria,2IXF8@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS3_k127_5856334_5	1142394.PSMK_03840	1.181e-91	314.0	COG0592@1|root,COG0592@2|Bacteria,2IY9S@203682|Planctomycetes	203682|Planctomycetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS3_k127_5856334_4	224308.BSU00010	2.665e-105	358.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS3_k127_5856334_1	330214.NIDE2073	7.503e-179	581.0	COG1389@1|root,COG1389@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
CMS3_k127_5856334_17	330214.NIDE2074	2.125e-14	79.0	COG1697@1|root,COG1697@2|Bacteria	2|Bacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF2220,DUF3322,TP6A_N
CMS3_k127_58824_3	1089548.KI783301_gene1217	2.318e-41	158.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli	91061|Bacilli	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_58824_2	234267.Acid_3960	1.307e-121	402.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_58824_7	378806.STAUR_2166	7.037e-12	74.0	29WSR@1|root,30IE2@2|Bacteria,1QX7C@1224|Proteobacteria,43C09@68525|delta/epsilon subdivisions,2X7B0@28221|Deltaproteobacteria,2YWMK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_58824_6	177439.DP1532	1.938e-12	79.0	COG4961@1|root,COG4961@2|Bacteria,1QVAG@1224|Proteobacteria,42Q1V@68525|delta/epsilon subdivisions,2WKTJ@28221|Deltaproteobacteria,2MNZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Putative Tad-like Flp pilus-assembly	-	-	-	-	-	-	-	-	-	-	-	-	Tad_C
CMS3_k127_58824_8	452637.Oter_0650	4.814e-08	65.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_58824_0	290315.Clim_0089	7.954e-233	734.0	COG0449@1|root,COG0449@2|Bacteria,1FDCR@1090|Chlorobi	1090|Chlorobi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS3_k127_58824_1	756272.Plabr_1389	9.432e-160	517.0	COG2256@1|root,COG2256@2|Bacteria,2IX8G@203682|Planctomycetes	203682|Planctomycetes	L	ATPase related to the helicase subunit of the Holliday junction resolvase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS3_k127_58824_4	762051.LKI_09915	4.954e-28	122.0	COG0212@1|root,COG4405@1|root,COG0212@2|Bacteria,COG4405@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,4AY11@81850|Leuconostocaceae	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS3_k127_58824_5	118163.Ple7327_1138	8.737e-17	88.0	COG0006@1|root,COG0006@2|Bacteria,1G0UJ@1117|Cyanobacteria,3VI2R@52604|Pleurocapsales	1117|Cyanobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_5884298_2	344747.PM8797T_07222	0.0001911	49.0	2EUDC@1|root,33MVR@2|Bacteria,2J1GP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5884298_0	304371.MCP_2802	3.469e-37	163.0	COG1404@1|root,arCOG06738@1|root,arCOG00702@2157|Archaea,arCOG06738@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Calx-beta,Inhibitor_I9,Peptidase_S8
CMS3_k127_5884298_1	5786.XP_003294087.1	2.869e-23	117.0	2D42B@1|root,2STKH@2759|Eukaryota,3XFXT@554915|Amoebozoa	554915|Amoebozoa	O	PA14 domain	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	Dicty_CTDC,PA14
CMS3_k127_5884377_0	223926.28806353	3.117e-68	240.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,1RZXV@1236|Gammaproteobacteria,1XVZK@135623|Vibrionales	135623|Vibrionales	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_5884377_2	247634.GPB2148_1282	3.436e-32	132.0	COG3247@1|root,COG3247@2|Bacteria,1QJA5@1224|Proteobacteria,1TH8U@1236|Gammaproteobacteria,1JB5Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
CMS3_k127_5884377_1	269797.Mbar_A1660	3.812e-52	191.0	COG5476@1|root,arCOG09072@2157|Archaea,2XYJG@28890|Euryarchaeota	28890|Euryarchaeota	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS3_k127_5888370_2	1198114.AciX9_3121	0.0005734	46.0	COG0457@1|root,COG0457@2|Bacteria,3Y46H@57723|Acidobacteria,2JHKM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5888370_0	266265.Bxe_B2483	2.137e-14	82.0	COG2374@1|root,COG4932@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,1R85W@1224|Proteobacteria,2VWBV@28216|Betaproteobacteria	28216|Betaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
CMS3_k127_5888370_1	448385.sce2055	0.0001863	52.0	COG3055@1|root,COG3203@1|root,COG3055@2|Bacteria,COG3203@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5894703_3	1267533.KB906733_gene3472	7.668e-83	292.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_5894703_8	575540.Isop_0069	5.758e-13	77.0	COG1595@1|root,COG1595@2|Bacteria,2J0K1@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
CMS3_k127_5894703_6	1499502.EV12_2045	1.603e-34	145.0	COG3315@1|root,COG3315@2|Bacteria,1GMZ3@1117|Cyanobacteria,1MNHE@1212|Prochloraceae	1117|Cyanobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_5894703_2	886293.Sinac_5242	4.039e-99	339.0	2C3PP@1|root,2Z954@2|Bacteria,2J2AE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5894703_0	886293.Sinac_5243	1.337e-143	467.0	COG0115@1|root,COG0115@2|Bacteria,2J2GT@203682|Planctomycetes	203682|Planctomycetes	H	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_5894703_1	926560.KE387023_gene2406	3.647e-99	356.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1WM5Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
CMS3_k127_5894703_4	1125863.JAFN01000001_gene457	2.533e-70	249.0	COG1624@1|root,COG1624@2|Bacteria,1N12B@1224|Proteobacteria,42UVR@68525|delta/epsilon subdivisions,2WQ2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
CMS3_k127_5894703_7	1209072.ALBT01000047_gene463	4.137e-29	134.0	2EPTW@1|root,33HED@2|Bacteria,1NK6N@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5894703_5	886293.Sinac_3220	9.352e-47	191.0	COG1807@1|root,COG1807@2|Bacteria,2IX04@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5902434_0	575540.Isop_3259	3.319e-189	603.0	COG0423@1|root,COG0423@2|Bacteria,2IY4R@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS3_k127_5902434_2	1123242.JH636436_gene287	8.355e-34	133.0	COG0724@1|root,COG0724@2|Bacteria,2J0SR@203682|Planctomycetes	203682|Planctomycetes	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_5902434_1	1123508.JH636442_gene4086	1.385e-112	374.0	COG1398@1|root,COG1398@2|Bacteria,2IZ45@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS3_k127_5902434_3	247639.MGP2080_06432	4.033e-13	83.0	COG1361@1|root,COG1361@2|Bacteria,1QVSF@1224|Proteobacteria,1SGFH@1236|Gammaproteobacteria,1J8X0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_5902867_0	1379270.AUXF01000002_gene1148	1.326e-127	418.0	COG4993@1|root,COG4993@2|Bacteria,1ZSSJ@142182|Gemmatimonadetes	2|Bacteria	G	PQQ-like domain	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
CMS3_k127_5930353_5	1173023.KE650771_gene3949	4.192e-13	79.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	GUN4,Pkinase,TPR_1,WD40
CMS3_k127_5930353_4	864051.BurJ1DRAFT_0531	1.023e-32	144.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_5930353_0	1340493.JNIF01000003_gene4071	4.314e-149	483.0	COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_5930353_2	1142394.PSMK_03510	9.125e-45	169.0	COG1595@1|root,COG1595@2|Bacteria,2IZ91@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5930353_3	335543.Sfum_3514	1.791e-34	143.0	COG3034@1|root,COG3034@2|Bacteria,1QTMV@1224|Proteobacteria,42W1K@68525|delta/epsilon subdivisions,2X5QE@28221|Deltaproteobacteria,2MS74@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS3_k127_5930353_1	1121403.AUCV01000035_gene3824	9.332e-100	344.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria,2MI66@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
CMS3_k127_5931494_4	1047013.AQSP01000134_gene1338	2.208e-45	171.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS3_k127_5931494_5	1191523.MROS_2096	7.562e-15	85.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
CMS3_k127_5931494_3	515635.Dtur_0729	4.058e-63	224.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
CMS3_k127_5931494_2	243231.GSU2921	5.126e-74	261.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,43U7R@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methionine synthase B12-binding module cap domain protein	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_5931494_1	1121091.AUMP01000008_gene3621	2.337e-96	323.0	COG1834@1|root,COG1834@2|Bacteria,1W71J@1239|Firmicutes,4HF31@91061|Bacilli	91061|Bacilli	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS3_k127_5931494_0	58123.JOFJ01000027_gene2790	1.564e-132	440.0	COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4EN0D@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_5931494_6	457415.HMPREF1006_02155	1.973e-10	70.0	COG3210@1|root,COG3210@2|Bacteria,3TB3U@508458|Synergistetes	508458|Synergistetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_5934503_0	404589.Anae109_3849	8.026e-33	136.0	COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,43APW@68525|delta/epsilon subdivisions,2X63P@28221|Deltaproteobacteria,2Z38U@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_5934503_1	936572.HMPREF1148_1403	7.143e-10	70.0	COG1560@1|root,COG1560@2|Bacteria,1U76T@1239|Firmicutes,4H2PH@909932|Negativicutes	909932|Negativicutes	M	Lipid A biosynthesis	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_5935530_4	1123242.JH636434_gene5299	5.001e-25	111.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5935530_1	1303518.CCALI_02780	3.273e-91	311.0	COG0320@1|root,COG0320@2|Bacteria	2|Bacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Lip_prot_lig_C,Radical_SAM
CMS3_k127_5935530_2	411490.ANACAC_02546	2.529e-41	162.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS3_k127_5935530_3	404589.Anae109_2451	4.757e-34	147.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,2YVD8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS3_k127_5935530_0	313606.M23134_01441	2.829e-157	508.0	COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,47JJH@768503|Cytophagia	976|Bacteroidetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1,2.6.1.88	ko:K00812,ko:K10907,ko:K14287	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052,R08618	RC00006,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5941497_22	1298920.KI911353_gene3439	4.902e-06	57.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,21Z2Z@1506553|Lachnoclostridium	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_5941497_6	85643.Tmz1t_2951	1.399e-72	259.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_5941497_3	316055.RPE_0607	8.654e-91	314.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_5941497_5	398767.Glov_2399	1.952e-83	288.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS3_k127_5941497_7	351627.Csac_0381	4.958e-53	197.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,42F39@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM ATPase, BadF BadG BcrA BcrD type	hgdC_1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
CMS3_k127_5941497_10	1242864.D187_010064	5.013e-51	184.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_5941497_20	483219.LILAB_32755	2.627e-10	70.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
CMS3_k127_5941497_18	926566.Terro_3006	1.963e-22	106.0	2C312@1|root,2Z7N1@2|Bacteria,3Y91F@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5941497_24	102107.XP_008240862.1	0.0006424	50.0	KOG1021@1|root,KOG1021@2759|Eukaryota,37QAT@33090|Viridiplantae,3GG8X@35493|Streptophyta,4JDM5@91835|fabids	35493|Streptophyta	T	Exostosin family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0012505,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	6.3.4.4	ko:K01939,ko:K20870	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT47	-	EGF_2,Exostosin
CMS3_k127_5941497_1	530564.Psta_2687	1.309e-172	550.0	COG0498@1|root,COG0498@2|Bacteria,2IXK6@203682|Planctomycetes	203682|Planctomycetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_5941497_23	1469557.JSWF01000045_gene486	4.844e-05	57.0	COG3291@1|root,COG4886@1|root,COG3291@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	htaA	-	3.4.21.72	ko:K01347	-	-	-	-	ko00000,ko01000,ko01002,ko02000,ko02044	1.B.12.3	-	-	CHU_C,HtaA
CMS3_k127_5941497_21	502025.Hoch_6539	8.639e-08	66.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5941497_16	158190.SpiGrapes_0302	5.962e-31	135.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_5941497_2	1187851.A33M_1445	4.398e-108	367.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,2TU9H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CG	PFAM glycosyl transferase, family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
CMS3_k127_5941497_11	1121937.AUHJ01000004_gene1125	7.5e-46	177.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1S48Y@1236|Gammaproteobacteria,467A1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_5941497_4	99598.Cal7507_3216	2.128e-90	313.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria,1HP1Q@1161|Nostocales	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5941497_19	1294273.roselon_02196	4.567e-12	77.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TUU4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_5941497_15	439235.Dalk_3416	1.718e-33	147.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42ZAR@68525|delta/epsilon subdivisions,2WU8I@28221|Deltaproteobacteria,2MN1D@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS3_k127_5941497_0	439235.Dalk_3415	7.411e-230	750.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MMWB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_5941497_13	439235.Dalk_3414	3.792e-40	169.0	COG1538@1|root,COG1538@2|Bacteria,1QFYM@1224|Proteobacteria,42RBK@68525|delta/epsilon subdivisions,2WMSG@28221|Deltaproteobacteria,2MJM2@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_5941497_8	234267.Acid_0852	3.784e-52	196.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
CMS3_k127_5941497_9	756272.Plabr_2749	3.69e-51	199.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_5941497_17	1226994.AMZB01000121_gene3420	2.343e-24	110.0	COG1846@1|root,COG1846@2|Bacteria,1RF3U@1224|Proteobacteria,1S4H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS3_k127_5941497_14	1463845.JOIG01000014_gene23	1.373e-34	139.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	bar	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
CMS3_k127_5941497_12	665959.HMPREF1013_03105	2.03e-43	165.0	COG2513@1|root,COG2513@2|Bacteria,1V76I@1239|Firmicutes,4HJYX@91061|Bacilli,1ZEH9@1386|Bacillus	91061|Bacilli	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
CMS3_k127_5942647_0	661478.OP10G_0991	2.235e-136	447.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,F5_F8_type_C,Glyco_hydro_38,Glyco_hydro_38C
CMS3_k127_5942647_1	518766.Rmar_1420	6.15e-98	327.0	COG1228@1|root,COG1228@2|Bacteria,4P0AG@976|Bacteroidetes,1FJ21@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_5942647_3	518766.Rmar_1420	4.14e-37	144.0	COG1228@1|root,COG1228@2|Bacteria,4P0AG@976|Bacteroidetes,1FJ21@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_5942647_2	518766.Rmar_1421	5.849e-75	255.0	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_5966237_1	862751.SACTE_2105	8.684e-09	68.0	COG0699@1|root,COG0699@2|Bacteria,2GM68@201174|Actinobacteria	201174|Actinobacteria	K	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
CMS3_k127_5966237_0	746697.Aeqsu_1982	5.207e-20	108.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,Laminin_G_3,P_proprotein
CMS3_k127_5966660_1	766499.C357_02731	4.869e-75	255.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	nasA	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_5966660_2	1454004.AW11_00622	2.97e-37	145.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2VSP4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Nitrite reductase NAD(P)H , small subunit	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
CMS3_k127_5966660_0	1255043.TVNIR_2420	1.1e-322	994.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,1RNGY@1236|Gammaproteobacteria,1WWFC@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.1,1.7.1.15	ko:K00362,ko:K05297	ko00071,ko00910,ko01120,map00071,map00910,map01120	M00530	R00787,R02000	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
CMS3_k127_5973984_4	247490.KSU1_C1158	0.0003002	53.0	2EKUM@1|root,33EIA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5973984_3	304371.MCP_2389	2.109e-67	244.0	COG4870@1|root,arCOG03614@2157|Archaea,2XZI4@28890|Euryarchaeota,2NAH7@224756|Methanomicrobia	224756|Methanomicrobia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
CMS3_k127_5973984_1	324602.Caur_1849	8.744e-109	359.0	COG1715@1|root,COG1715@2|Bacteria	2|Bacteria	V	Restriction endonuclease	mrr	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
CMS3_k127_5973984_2	1192034.CAP_4147	8.058e-107	355.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2YZ9D@29|Myxococcales	28221|Deltaproteobacteria	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS3_k127_5973984_0	886293.Sinac_3551	1.563e-110	369.0	COG2509@1|root,COG2509@2|Bacteria,2IWT5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	NAD_binding_8
CMS3_k127_5991893_1	401053.AciPR4_3251	2.42e-20	98.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_5991893_0	1121904.ARBP01000018_gene2643	3.274e-37	158.0	COG5295@1|root,COG5295@2|Bacteria,4PHWW@976|Bacteroidetes,47ST5@768503|Cytophagia	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5991893_3	1137281.D778_01491	4.136e-07	63.0	COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,1I1PS@117743|Flavobacteriia	976|Bacteroidetes	MUW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CMS3_k127_5991893_2	324602.Caur_0299	4.762e-20	104.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_5991893_4	1262449.CP6013_0599	5.51e-05	49.0	COG1309@1|root,COG1309@2|Bacteria,1VN1R@1239|Firmicutes,24J3V@186801|Clostridia,36J8Z@31979|Clostridiaceae	186801|Clostridia	K	PFAM regulatory protein TetR	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
CMS3_k127_6014353_1	1502851.FG93_01066	1.805e-57	206.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_6014353_3	189753.AXAS01000085_gene6024	2.038e-12	68.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
CMS3_k127_6014353_0	1454004.AW11_03028	3.967e-136	443.0	COG2220@1|root,COG2220@2|Bacteria,1R5GU@1224|Proteobacteria,2VPH1@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_6014353_2	316067.Geob_0241	3.574e-15	80.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,42R1Q@68525|delta/epsilon subdivisions,2WN15@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_6014965_8	575540.Isop_1256	3.137e-40	166.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Ribonuc_L-PSP
CMS3_k127_6014965_12	858215.Thexy_0665	3.05e-16	92.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,42EZJ@68295|Thermoanaerobacterales	186801|Clostridia	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6014965_1	575540.Isop_1258	1.772e-97	334.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_6014965_4	575540.Isop_1259	2.1e-60	237.0	COG1228@1|root,COG1228@2|Bacteria,2IYFS@203682|Planctomycetes	203682|Planctomycetes	Q	COG1228 Imidazolonepropionase and related	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_6014965_3	575540.Isop_1260	1.495e-74	269.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	2|Bacteria	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6014965_7	1120958.AULD01000005_gene1574	2.464e-40	168.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,4FMUP@85023|Microbacteriaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6014965_10	748449.Halha_1677	6.865e-23	112.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,3WB19@53433|Halanaerobiales	186801|Clostridia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6014965_9	1089553.Tph_c22350	2.564e-34	149.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,42EZJ@68295|Thermoanaerobacterales	186801|Clostridia	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6014965_6	237368.SCABRO_00204	1.074e-44	170.0	COG1386@1|root,COG1386@2|Bacteria,2IZNB@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS3_k127_6014965_11	189753.AXAS01000068_gene4928	3.554e-18	98.0	COG1649@1|root,COG1649@2|Bacteria,1R6SN@1224|Proteobacteria,2U2S1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6014965_0	1232410.KI421414_gene2877	2.041e-169	554.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,43TVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein CapD	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CMS3_k127_6014965_2	886293.Sinac_2664	1.801e-81	287.0	COG0142@1|root,COG0142@2|Bacteria,2IXUE@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_6014965_5	446470.Snas_3300	5.443e-45	169.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4EYT0@85014|Glycomycetales	201174|Actinobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0002682,GO:0002683,GO:0005575,GO:0005576,GO:0008150,GO:0009605,GO:0009607,GO:0031347,GO:0031348,GO:0035821,GO:0040007,GO:0043207,GO:0044003,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0075136,GO:0080134	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
CMS3_k127_603574_7	366602.Caul_4976	3.595e-08	56.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,2KFB5@204458|Caulobacterales	204458|Caulobacterales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_603574_4	595460.RRSWK_03118	3.051e-46	178.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_603574_0	204669.Acid345_3021	0.0	1116.0	COG4447@1|root,COG4447@2|Bacteria,3Y6ZR@57723|Acidobacteria	57723|Acidobacteria	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_603574_3	204669.Acid345_3020	2.277e-49	186.0	COG2834@1|root,COG2834@2|Bacteria,3Y7NW@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_603574_5	1247963.JPHU01000006_gene187	4.101e-46	173.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K09565	ko04020,ko04022,ko05012,ko05016,ko05145,map04020,map04022,map05012,map05016,map05145	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_603574_2	518766.Rmar_1438	3.592e-156	512.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1438|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_603574_1	518766.Rmar_1439	1.79e-213	685.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1439|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_603574_6	344747.PM8797T_24766	1.478e-11	76.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad,Tad_C
CMS3_k127_6053285_2	1144275.COCOR_03665	6.478e-33	147.0	COG5492@1|root,COG5492@2|Bacteria,1PBEQ@1224|Proteobacteria	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6053285_4	1174684.EBMC1_11850	0.0001584	54.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
CMS3_k127_6053285_3	391603.FBALC1_06413	8.172e-13	81.0	COG3832@1|root,COG3832@2|Bacteria,4P4GT@976|Bacteroidetes,1I9X6@117743|Flavobacteriia	976|Bacteroidetes	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6053285_1	1479238.JQMZ01000001_gene755	2.372e-37	149.0	COG3832@1|root,COG3832@2|Bacteria,1PW4F@1224|Proteobacteria,2V7AT@28211|Alphaproteobacteria,4404P@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_6053285_0	861299.J421_1186	2.141e-58	208.0	COG1309@1|root,COG1309@2|Bacteria,1ZV9M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
CMS3_k127_6054581_2	880073.Calab_0614	5.847e-75	256.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CMS3_k127_6054581_4	760568.Desku_0718	1.279e-70	250.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,261FK@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS3_k127_6054581_0	1501230.ET33_00555	1.417e-136	443.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,26RIV@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	spsJ	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_6054581_1	330214.NIDE3016	3.843e-110	362.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_6054581_3	56780.SYN_00576	5.555e-73	250.0	COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria,42RZA@68525|delta/epsilon subdivisions,2WNBP@28221|Deltaproteobacteria,2MRPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	WxcM-like, C-terminal	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS3_k127_6054581_6	1382306.JNIM01000001_gene1224	8.818e-19	101.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
CMS3_k127_6054581_5	1123508.JH636440_gene2667	1.486e-27	130.0	COG1269@1|root,COG1269@2|Bacteria,2IZU8@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS3_k127_6056074_1	404380.Gbem_0461	1.521e-20	96.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,42MYB@68525|delta/epsilon subdivisions,2WIUY@28221|Deltaproteobacteria,43TUD@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	e3 binding domain	bkdF	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_6056074_0	335543.Sfum_2647	5.808e-134	434.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2MR64@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_6071439_12	909663.KI867150_gene1149	3.379e-11	71.0	COG0664@1|root,COG0664@2|Bacteria,1NAYS@1224|Proteobacteria,42W1E@68525|delta/epsilon subdivisions,2WS96@28221|Deltaproteobacteria,2MS9T@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_6071439_8	1535422.ND16A_3836	1.598e-39	163.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,1RWBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3
CMS3_k127_6071439_2	1379698.RBG1_1C00001G0855	2.76e-130	445.0	COG0243@1|root,COG0243@2|Bacteria,2NPRJ@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	qrcB	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_6071439_4	1379698.RBG1_1C00001G0856	8.927e-92	306.0	COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
CMS3_k127_6071439_1	1379698.RBG1_1C00001G0857	8.297e-171	552.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6071439_5	1379698.RBG1_1C00001G0858	7.217e-67	250.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
CMS3_k127_6071439_11	269799.Gmet_1809	6.033e-22	102.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6071439_7	1541960.KQ78_00378	5.461e-51	202.0	COG3437@1|root,COG3437@2|Bacteria,3WU98@544448|Tenericutes	2|Bacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,GAF_2,GGDEF,HD,HD_5,HisKA_7TM
CMS3_k127_6071439_9	243090.RB7985	6.774e-36	141.0	COG1446@1|root,COG4319@1|root,COG1446@2|Bacteria,COG4319@2|Bacteria,2IZ4V@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2,DUF4440
CMS3_k127_6071439_10	234267.Acid_0104	6.669e-28	132.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_6071439_6	1142394.PSMK_11590	6.421e-60	225.0	COG0568@1|root,COG0568@2|Bacteria,2IY72@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03086,ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
CMS3_k127_6071439_3	886293.Sinac_5745	1.632e-93	321.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_6071439_0	1121422.AUMW01000026_gene381	1.039e-206	655.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8,1.2.1.99	ko:K00130,ko:K00135,ko:K09472,ko:K22187	ko00040,ko00250,ko00260,ko00310,ko00330,ko00350,ko00650,ko00760,ko01100,ko01120,map00040,map00250,map00260,map00310,map00330,map00350,map00650,map00760,map01100,map01120	M00027,M00136,M00555	R00713,R00714,R02401,R02565,R02566,R07417,R07418,R11768	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_6086034_0	626887.J057_15840	2.302e-103	346.0	COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,1RZGT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Endo alpha-1,4 polygalactosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
CMS3_k127_6086034_1	426117.M446_3645	2.587e-09	66.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,1JTMF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
CMS3_k127_6087027_7	935567.JAES01000003_gene230	9.176e-72	248.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1P31Y@1224|Proteobacteria,1RQNS@1236|Gammaproteobacteria,1X4XU@135614|Xanthomonadales	135614|Xanthomonadales	C	MFS transporter	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_6087027_1	935863.AWZR01000003_gene2795	1.511e-176	560.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6087027_3	1173026.Glo7428_1703	1.625e-123	404.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria	1117|Cyanobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
CMS3_k127_6087027_0	29581.BW37_03653	2.154e-317	1011.0	COG0308@1|root,COG0308@2|Bacteria,1PTWJ@1224|Proteobacteria,2WBWI@28216|Betaproteobacteria,476KD@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,Peptidase_M1
CMS3_k127_6087027_4	1163407.UU7_08758	5.213e-118	390.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,1RQ0Z@1236|Gammaproteobacteria,1X4K5@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	yfiL	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_6087027_9	1121129.KB903368_gene872	4.497e-35	150.0	COG0526@1|root,COG0526@2|Bacteria,4P759@976|Bacteroidetes	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6087027_6	1122604.JONR01000006_gene2603	1.587e-74	258.0	COG0500@1|root,COG2226@2|Bacteria,1MVXG@1224|Proteobacteria,1S4GS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_6087027_8	1385935.N836_20445	6.132e-68	263.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
CMS3_k127_6087027_11	247490.KSU1_C1544	0.0006492	53.0	COG2755@1|root,COG5306@1|root,COG2755@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	exbB2	-	3.4.14.5	ko:K01278,ko:K03561,ko:K12287	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko02044,ko04090,ko04147	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
CMS3_k127_6087027_5	234267.Acid_4709	9.783e-79	272.0	COG3217@1|root,COG3217@2|Bacteria,3Y5TQ@57723|Acidobacteria	57723|Acidobacteria	S	MOSC N-terminal beta barrel domain	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
CMS3_k127_6087027_2	1246995.AFR_17080	9.315e-168	539.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4D8KQ@85008|Micromonosporales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
CMS3_k127_6087027_10	1485544.JQKP01000008_gene1781	3.226e-09	62.0	2EAET@1|root,334IB@2|Bacteria,1N6S1@1224|Proteobacteria,2W5KM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6098558_1	1396418.BATQ01000048_gene6234	8.007e-05	55.0	2BY38@1|root,33IVS@2|Bacteria,46WI2@74201|Verrucomicrobia	1396418.BATQ01000048_gene6234|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6098558_0	240016.ABIZ01000001_gene4541	2.8e-10	73.0	2BY38@1|root,33IVS@2|Bacteria,46WI2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6102696_1	234267.Acid_7680	1.007e-26	112.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_6102696_0	234267.Acid_4431	4.186e-107	375.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_6116112_2	1313172.YM304_00320	8.734e-20	89.0	2EE69@1|root,3380V@2|Bacteria,2GR09@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6116112_0	247634.GPB2148_3541	2.748e-92	333.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,1SJX0@1236|Gammaproteobacteria,1J8GZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS3_k127_6116112_1	1248917.ANFX01000019_gene2336	1.131e-56	199.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria,2K9H3@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_6129036_1	886293.Sinac_4025	0.0001891	53.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8,WD40
CMS3_k127_6129036_0	765420.OSCT_0910	5.83e-85	306.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
CMS3_k127_614425_1	272134.KB731324_gene6659	0.0001062	51.0	COG3039@1|root,COG3039@2|Bacteria,1G1EK@1117|Cyanobacteria,1HEKZ@1150|Oscillatoriales	1117|Cyanobacteria	L	SPTR Transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
CMS3_k127_614425_0	886293.Sinac_1805	2.185e-166	537.0	COG0445@1|root,COG0445@2|Bacteria,2IXGA@203682|Planctomycetes	203682|Planctomycetes	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS3_k127_6148382_2	251221.35211558	3.11e-34	154.0	COG1404@1|root,COG2706@1|root,COG3391@1|root,COG1404@2|Bacteria,COG2706@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_S8,TIG,VCBS
CMS3_k127_6148382_0	1250006.JHZZ01000001_gene3312	4.051e-53	217.0	COG2247@1|root,COG2273@1|root,COG2911@1|root,COG2982@1|root,COG3266@1|root,COG2247@2|Bacteria,COG2273@2|Bacteria,COG2911@2|Bacteria,COG2982@2|Bacteria,COG3266@2|Bacteria,4PKAY@976|Bacteroidetes,1IKRS@117743|Flavobacteriia	976|Bacteroidetes	M	Psort location Extracellular, score 9.64	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS3_k127_6148382_4	716544.wcw_1768	5.534e-32	130.0	COG2606@1|root,COG2606@2|Bacteria,2JHH6@204428|Chlamydiae	204428|Chlamydiae	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS3_k127_6148382_1	273075.Ta0881m	6.061e-50	184.0	COG0663@1|root,arCOG01849@2157|Archaea,2XWNM@28890|Euryarchaeota	28890|Euryarchaeota	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS3_k127_6148382_3	313606.M23134_00255	4.304e-32	144.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
CMS3_k127_6160118_2	1229909.NSED_04975	1.424e-33	153.0	COG1361@1|root,arCOG04500@1|root,arCOG02079@2157|Archaea,arCOG04500@2157|Archaea	2157|Archaea	O	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CARDB,NosD,S_layer_C
CMS3_k127_6160118_0	1192034.CAP_8277	3.81e-67	263.0	COG3266@1|root,COG3266@2|Bacteria,1QZBM@1224|Proteobacteria,42TG7@68525|delta/epsilon subdivisions,2WQPM@28221|Deltaproteobacteria,2Z3I2@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_6160118_3	1348583.ATLH01000018_gene2436	4.275e-33	151.0	COG4257@1|root,COG5492@1|root,COG4257@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,DUF5011,He_PIG,SprB
CMS3_k127_6160118_1	96561.Dole_1790	7.183e-38	167.0	COG1319@1|root,COG1653@1|root,COG5492@1|root,COG1319@2|Bacteria,COG1653@2|Bacteria,COG5492@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6160118_4	1320556.AVBP01000007_gene480	0.0003415	46.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6179982_4	1089550.ATTH01000001_gene1136	2.849e-72	267.0	COG0348@1|root,COG0492@1|root,COG1249@1|root,COG0348@2|Bacteria,COG0492@2|Bacteria,COG1249@2|Bacteria,4PIT2@976|Bacteroidetes,1FJYA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
CMS3_k127_6179982_3	1304888.ATWF01000001_gene1926	4.399e-77	266.0	COG0623@1|root,COG0623@2|Bacteria,2GEPG@200930|Deferribacteres	200930|Deferribacteres	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_6179982_2	314230.DSM3645_07730	6.025e-93	313.0	COG0020@1|root,COG0020@2|Bacteria,2IX6Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS3_k127_6179982_1	886293.Sinac_6804	7.921e-132	435.0	COG0104@1|root,COG0104@2|Bacteria,2IWZH@203682|Planctomycetes	203682|Planctomycetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS3_k127_6179982_0	378806.STAUR_3846	5.885e-231	722.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,43BWY@68525|delta/epsilon subdivisions,2X77Q@28221|Deltaproteobacteria,2YXSH@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamine synthetase, beta-Grasp domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_6179982_6	1191523.MROS_1192	7.217e-38	155.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_6179982_5	1036674.A28LD_0671	8.466e-51	189.0	2DPEU@1|root,331SS@2|Bacteria,1NDKB@1224|Proteobacteria,1RTE7@1236|Gammaproteobacteria,2QG29@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
CMS3_k127_6192812_0	1027371.GOALK_093_00570	9.767e-29	126.0	COG0863@1|root,COG0863@2|Bacteria,2HT6C@201174|Actinobacteria,4GG8Y@85026|Gordoniaceae	201174|Actinobacteria	H	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CMS3_k127_6194882_2	1123278.KB893427_gene1235	6.15e-23	116.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6194882_1	1192034.CAP_1358	8.857e-24	119.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
CMS3_k127_6194882_0	1047013.AQSP01000076_gene1470	5.544e-47	171.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_6195638_1	945713.IALB_1831	4.986e-13	81.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
CMS3_k127_6195638_2	7159.AAEL008062-PA	0.0001575	53.0	2CMRF@1|root,2QRK8@2759|Eukaryota,38BZ6@33154|Opisthokonta,3BC6D@33208|Metazoa,3CRA6@33213|Bilateria,41W09@6656|Arthropoda,3SING@50557|Insecta,44Y9H@7147|Diptera,45DBE@7148|Nematocera	33208|Metazoa	O	Cartilage oligomeric matrix protein	COMP	GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181	-	ko:K04659	ko04145,ko04151,ko04510,ko04512,ko05144,ko05165,map04145,map04151,map04510,map04512,map05144,map05165	-	-	-	ko00000,ko00001,ko00536,ko04131,ko04147,ko04516	-	-	-	COMP,EGF,EGF_CA,TSP_3,TSP_C
CMS3_k127_6195638_0	1123242.JH636434_gene3289	1.011e-31	133.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS3_k127_619631_1	1163409.UUA_08726	4.252e-26	111.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1X5QC@135614|Xanthomonadales	135614|Xanthomonadales	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_619631_0	551275.KB899544_gene1472	2.807e-89	311.0	28M2S@1|root,2ZAH5@2|Bacteria,1MVH5@1224|Proteobacteria,2V6CQ@28211|Alphaproteobacteria,43WPI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6208909_6	324602.Caur_0299	4.275e-12	70.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_6208909_9	926569.ANT_03060	1.717e-07	58.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6208909_10	264462.Bd2133	6.367e-06	59.0	COG0729@1|root,COG3210@1|root,COG0729@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K07277,ko:K07278,ko:K21449	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4,1.B.40.2	-	-	Bac_surface_Ag,Beta_helix,PATR,POTRA,Peptidase_S74
CMS3_k127_6208909_4	316274.Haur_2192	1.911e-33	148.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_6208909_7	882083.SacmaDRAFT_4670	5.437e-11	71.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4EBBC@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigD	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_6208909_1	1267533.KB906733_gene3472	7.707e-147	501.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_6208909_2	1122176.KB903565_gene3379	6.529e-86	323.0	COG2304@1|root,COG2304@2|Bacteria,4PKD0@976|Bacteroidetes,1IXV1@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
CMS3_k127_6208909_5	1144313.PMI10_03989	1.72e-15	92.0	COG3291@1|root,COG3291@2|Bacteria,4PPKT@976|Bacteroidetes,1IKQC@117743|Flavobacteriia,2NVPF@237|Flavobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6208909_3	530564.Psta_3450	4.467e-75	282.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6208909_11	1385517.N800_08400	1.045e-05	57.0	COG1680@1|root,COG1680@2|Bacteria,1RBDE@1224|Proteobacteria,1RYDP@1236|Gammaproteobacteria,1X4U9@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_6208909_0	661478.OP10G_1525	2.448e-179	595.0	COG2352@1|root,COG2352@2|Bacteria	2|Bacteria	C	phosphoenolpyruvate carboxylase activity	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ppc	PEPcase
CMS3_k127_6208909_8	391625.PPSIR1_40929	7.699e-08	56.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,4360M@68525|delta/epsilon subdivisions,2X2HZ@28221|Deltaproteobacteria,2Z0WC@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_6212282_7	391008.Smal_2774	4.491e-23	106.0	2AR90@1|root,31GIV@2|Bacteria,1QGZ5@1224|Proteobacteria,1TEFX@1236|Gammaproteobacteria,1X953@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6212282_6	1224318.DT73_19950	1.514e-26	124.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,1RSBU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Carbohydrate-selective porin	oprB	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
CMS3_k127_6212282_3	1033810.HLPCO_001694	2.498e-42	166.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_6212282_1	243090.RB8966	2.154e-204	649.0	COG0459@1|root,COG0459@2|Bacteria,2IWZS@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_6212282_4	530564.Psta_3024	6.012e-33	132.0	COG0234@1|root,COG0234@2|Bacteria,2J0E5@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_6212282_0	237368.SCABRO_03915	1.284e-210	666.0	COG0459@1|root,COG0459@2|Bacteria,2IXJW@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_6212282_2	575540.Isop_1572	1.324e-111	372.0	COG0484@1|root,COG0484@2|Bacteria,2IXQJ@203682|Planctomycetes	203682|Planctomycetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_6212282_5	1123242.JH636434_gene3286	5.656e-30	127.0	COG0576@1|root,COG0576@2|Bacteria,2J0MS@203682|Planctomycetes	203682|Planctomycetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS3_k127_6212282_8	478741.JAFS01000002_gene63	1.01e-19	92.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia,37GYP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_6212282_9	443152.MDG893_01335	3.701e-12	69.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,1SC7M@1236|Gammaproteobacteria,468WS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
CMS3_k127_6212282_10	1142394.PSMK_27160	1.454e-07	56.0	COG2165@1|root,COG2165@2|Bacteria,2IXM1@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_6219388_0	886293.Sinac_4372	3.818e-192	611.0	COG1861@1|root,COG1861@2|Bacteria,2J3F7@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS3_k127_6254464_1	561229.Dd1591_0214	1.66e-42	161.0	COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,1RSHY@1236|Gammaproteobacteria,2JF4A@204037|Dickeya	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CMS3_k127_6254464_0	886293.Sinac_5211	1.264e-45	169.0	COG3293@1|root,COG3293@2|Bacteria,2J0XQ@203682|Planctomycetes	203682|Planctomycetes	L	COGs COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF4096
CMS3_k127_6257492_0	402881.Plav_1766	5.568e-135	439.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,1JNSZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04116	ko00362,ko01120,map00362,map01120	M00540	R05620	RC00004,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6257492_2	880072.Desac_1404	0.0002238	52.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K10936,ko:K16079	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.4.2.1	-	-	OMP_b-brl
CMS3_k127_6257492_1	1380394.JADL01000003_gene5006	3.241e-23	102.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria	1224|Proteobacteria	Q	taurine catabolism dioxygenase	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_6312137_0	1121405.dsmv_1098	5.342e-115	381.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2MN0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS3_k127_6312137_1	745277.GRAQ_01474	7.313e-09	64.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,3FF64@34037|Rahnella	1236|Gammaproteobacteria	P	ABC-type Fe3 transport system, permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS3_k127_6313556_0	1396418.BATQ01000113_gene4691	1.62e-26	125.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_6328027_1	1336233.JAEH01000002_gene1343	1.152e-26	124.0	2DKWY@1|root,30NX3@2|Bacteria,1RBMB@1224|Proteobacteria,1S5SW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6328027_2	1502850.FG91_02261	5.323e-08	65.0	COG2333@1|root,COG2333@2|Bacteria,1Q70M@1224|Proteobacteria,2USQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6328027_0	1454004.AW11_03981	3.342e-56	206.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VIN1@28216|Betaproteobacteria,1KR64@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	ET	PFAM extracellular solute-binding protein family 3	aapJ	-	-	ko:K02030,ko:K09969,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
CMS3_k127_6345930_0	479434.Sthe_2294	7.245e-241	779.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
CMS3_k127_6345930_13	42256.RradSPS_2397	3.08e-06	59.0	COG0438@1|root,COG0438@2|Bacteria,2HENX@201174|Actinobacteria,4CRKC@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_6345930_6	1210884.HG799462_gene7894	9.235e-64	233.0	COG0196@1|root,COG0196@2|Bacteria,2IYZQ@203682|Planctomycetes	203682|Planctomycetes	H	riboflavin biosynthesis protein	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS3_k127_6345930_8	1210884.HG799462_gene8697	1.686e-49	190.0	COG0618@1|root,COG0618@2|Bacteria,2IYQ0@203682|Planctomycetes	203682|Planctomycetes	S	phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_6345930_4	1142394.PSMK_28460	3.458e-78	268.0	COG0740@1|root,COG0740@2|Bacteria,2IXQN@203682|Planctomycetes	203682|Planctomycetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS3_k127_6345930_5	575540.Isop_2398	7.719e-65	229.0	COG0740@1|root,COG0740@2|Bacteria,2IYFK@203682|Planctomycetes	203682|Planctomycetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS3_k127_6345930_7	344747.PM8797T_25511	1.542e-58	224.0	COG0544@1|root,COG0544@2|Bacteria,2IXGD@203682|Planctomycetes	203682|Planctomycetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
CMS3_k127_6345930_1	555088.DealDRAFT_2869	3.491e-178	563.0	COG1830@1|root,COG1830@2|Bacteria,1TR60@1239|Firmicutes	1239|Firmicutes	G	DeoC/LacD family aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DeoC
CMS3_k127_6345930_12	629773.AORY01000001_gene2186	3.841e-07	61.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,2K18A@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS3_k127_6345930_2	1142394.PSMK_14530	1.749e-156	502.0	COG1077@1|root,COG1077@2|Bacteria,2IXSJ@203682|Planctomycetes	203682|Planctomycetes	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_6345930_9	1267534.KB906756_gene707	5.553e-24	106.0	2CIGD@1|root,2ZM6I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6345930_3	746697.Aeqsu_2660	1.116e-129	462.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_6345930_10	946362.XP_004992548.1	1.243e-19	106.0	28N08@1|root,2QUJ0@2759|Eukaryota	2759|Eukaryota	-	-	MUC4	GO:0001894,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005102,GO:0005176,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007586,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010669,GO:0012505,GO:0016020,GO:0016021,GO:0016266,GO:0019538,GO:0022600,GO:0023052,GO:0030197,GO:0030277,GO:0031012,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0034645,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048871,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0071704,GO:0071944,GO:0080134,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K22017	-	-	-	-	ko00000,ko04131	-	-	-	NIDO,VWD
CMS3_k127_6352998_2	595460.RRSWK_05444	8.129e-59	224.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
CMS3_k127_6352998_3	1123242.JH636436_gene633	1.385e-33	136.0	COG1694@1|root,COG1694@2|Bacteria,2J047@203682|Planctomycetes	203682|Planctomycetes	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS3_k127_6352998_0	880073.Calab_2000	1.455e-99	334.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_6352998_4	365046.Rta_32630	3.216e-07	61.0	2DKWD@1|root,30KRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS3_k127_6352998_1	234267.Acid_4393	1.496e-89	303.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6357001_0	767817.Desgi_3972	4.542e-62	220.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,264EG@186807|Peptococcaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_6362033_1	1535422.ND16A_2156	9.419e-09	67.0	COG1800@1|root,COG5184@1|root,COG1800@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_5,CHU_C,CW_binding_2,Cadherin-like,CarboxypepD_reg,Laminin_G_3,SLH
CMS3_k127_6362033_0	45351.EDO39043	1.002e-20	107.0	KOG1225@1|root,KOG1225@2759|Eukaryota,39NN9@33154|Opisthokonta,3CQ6R@33208|Metazoa	33208|Metazoa	T	Epidermal growth factor-like domain.	-	-	-	-	-	-	-	-	-	-	-	-	EGF_2
CMS3_k127_6376447_0	873533.HMPREF0663_10968	3.145e-147	480.0	COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,2FNSI@200643|Bacteroidia	976|Bacteroidetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS3_k127_6376447_6	1297742.A176_03147	4.63e-07	64.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,42V3F@68525|delta/epsilon subdivisions,2WR8K@28221|Deltaproteobacteria,2YVGH@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ enzyme repeat	yfgL	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS3_k127_6376447_3	344747.PM8797T_29952	5.087e-91	313.0	COG2373@1|root,COG2373@2|Bacteria,2IYJD@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_6376447_1	530564.Psta_2701	7.885e-139	458.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_6376447_4	1123508.JH636450_gene7066	3.061e-89	304.0	COG1721@1|root,COG1721@2|Bacteria,2IY2F@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_6376447_2	530564.Psta_2699	3.803e-96	343.0	COG1874@1|root,COG2304@1|root,COG1874@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_6376447_5	530564.Psta_2696	7.901e-48	189.0	COG2304@1|root,COG2304@2|Bacteria,2IYCE@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_6379520_1	886293.Sinac_0142	2.154e-61	222.0	COG0526@1|root,COG0526@2|Bacteria,2IZW1@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
CMS3_k127_6379520_2	1142394.PSMK_03050	2.055e-44	170.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
CMS3_k127_6379520_0	710111.FraQA3DRAFT_3607	1.397e-61	220.0	COG0007@1|root,COG0007@2|Bacteria,2GK3B@201174|Actinobacteria,4ERSU@85013|Frankiales	201174|Actinobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,NAD_binding_7,TP_methylase
CMS3_k127_6400896_0	1192034.CAP_1358	4.741e-08	68.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
CMS3_k127_641221_2	1125863.JAFN01000001_gene3410	7.214e-76	267.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS3_k127_641221_5	1123376.AUIU01000018_gene44	0.0001622	51.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_641221_1	1142394.PSMK_22590	5.258e-78	290.0	COG1639@1|root,COG4191@1|root,COG1639@2|Bacteria,COG4191@2|Bacteria,2J037@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA
CMS3_k127_641221_3	314230.DSM3645_16135	1e-69	242.0	COG0745@1|root,COG0745@2|Bacteria,2IY82@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
CMS3_k127_641221_0	202752.JL53_00025	6.625e-178	579.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,26K2A@186820|Listeriaceae	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS3_k127_641221_4	886293.Sinac_5678	1.087e-48	189.0	COG1960@1|root,COG1960@2|Bacteria,2IZ43@203682|Planctomycetes	203682|Planctomycetes	I	COG1960 Acyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_N
CMS3_k127_6422763_2	1123371.ATXH01000028_gene24	4.447e-36	140.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_6422763_3	1232410.KI421421_gene3421	5.241e-17	96.0	2E1I6@1|root,32WW2@2|Bacteria,1NTI4@1224|Proteobacteria,42YDB@68525|delta/epsilon subdivisions,2WTNY@28221|Deltaproteobacteria,43TFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
CMS3_k127_6422763_1	1379698.RBG1_1C00001G0779	3.929e-86	306.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
CMS3_k127_6422763_0	671143.DAMO_0821	3.34e-114	379.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
CMS3_k127_6424766_3	396588.Tgr7_1199	8.402e-47	178.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1WYUS@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
CMS3_k127_6424766_6	1210884.HG799464_gene10721	3.353e-35	139.0	COG1853@1|root,COG1853@2|Bacteria,2J4S0@203682|Planctomycetes	203682|Planctomycetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_6424766_4	243231.GSU1562	3.334e-41	158.0	COG0011@1|root,COG0011@2|Bacteria,1N2GU@1224|Proteobacteria,42UPF@68525|delta/epsilon subdivisions,2WR94@28221|Deltaproteobacteria,43W2X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
CMS3_k127_6424766_11	384765.SIAM614_16407	4.703e-17	85.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2UC33@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	nitrite reductase	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
CMS3_k127_6424766_2	886293.Sinac_7213	3.467e-87	297.0	COG0053@1|root,COG0053@2|Bacteria,2IY05@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS3_k127_6424766_9	378806.STAUR_6760	2.071e-27	121.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,2YXEI@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS3_k127_6424766_13	1112217.PPL19_13535	3.848e-12	73.0	2EIWT@1|root,33CN4@2|Bacteria,1QXAW@1224|Proteobacteria,1T36P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6424766_8	1123261.AXDW01000020_gene1710	3.025e-28	123.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_6424766_7	1125863.JAFN01000001_gene3046	5.459e-29	123.0	2CEMF@1|root,33GFG@2|Bacteria,1NIQ6@1224|Proteobacteria,42X94@68525|delta/epsilon subdivisions,2WSWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6424766_0	575540.Isop_1372	1.005e-204	659.0	COG3591@1|root,COG3591@2|Bacteria,2IXPD@203682|Planctomycetes	203682|Planctomycetes	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CMS3_k127_6424766_10	36331.EPrPI00000019526	5.088e-23	114.0	COG3914@1|root,KOG4626@2759|Eukaryota,1MFQT@121069|Pythiales	121069|Pythiales	GOT	UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_8
CMS3_k127_6424766_1	335543.Sfum_1617	2.516e-124	419.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_6424766_5	314230.DSM3645_26789	6.497e-37	148.0	2DZX2@1|root,32VM6@2|Bacteria,2J2WS@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6434495_3	278957.ABEA03000041_gene2175	0.0001146	49.0	COG2165@1|root,COG2165@2|Bacteria,46XJA@74201|Verrucomicrobia,3K9FD@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS3_k127_6434495_0	877414.ATWA01000020_gene2022	3.069e-32	132.0	COG0454@1|root,COG0456@2|Bacteria,1VAZN@1239|Firmicutes,24FQG@186801|Clostridia	186801|Clostridia	K	Acetyltransferase GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS3_k127_6434495_1	469381.Dpep_1278	1.196e-06	60.0	COG3018@1|root,COG3018@2|Bacteria,3TC6V@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6434495_2	349102.Rsph17025_1619	3.65e-05	55.0	COG3018@1|root,COG3018@2|Bacteria,1N8R1@1224|Proteobacteria,2UC44@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	LPP20 lipoprotein	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
CMS3_k127_6450315_2	234267.Acid_7539	1.153e-16	81.0	COG0724@1|root,COG0724@2|Bacteria,3Y59V@57723|Acidobacteria	57723|Acidobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_6450315_1	671143.DAMO_2755	1.195e-85	299.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_6450315_0	1089552.KI911559_gene1478	1.177e-162	530.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,2JPAU@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS3_k127_650206_0	1469613.JT55_13185	4.806e-64	228.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CMS3_k127_650206_1	243090.RB27	4.656e-46	181.0	2E2RY@1|root,32XUA@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS3_k127_650206_3	1123229.AUBC01000004_gene3242	5.896e-21	105.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,1MVN2@1224|Proteobacteria,2TUT9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	HJ	Cyanophycin synthetase	cphA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,GSH-S_ATP,RimK
CMS3_k127_650206_2	756272.Plabr_3569	6.296e-34	138.0	COG0515@1|root,COG0515@2|Bacteria,2IZFV@203682|Planctomycetes	203682|Planctomycetes	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6558392_0	1298867.AUES01000040_gene951	1.446e-19	92.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JTJE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
CMS3_k127_6558392_1	1192034.CAP_1358	6.446e-12	81.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
CMS3_k127_6601326_2	1205910.B005_1750	5.565e-31	125.0	COG0451@1|root,COG0451@2|Bacteria,2GN75@201174|Actinobacteria,4ENH5@85012|Streptosporangiales	201174|Actinobacteria	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_6601326_0	575540.Isop_0060	1.444e-161	520.0	COG1004@1|root,COG1004@2|Bacteria,2IXM4@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_6601326_1	693979.Bache_1460	2.233e-76	277.0	COG0793@1|root,COG0793@2|Bacteria,4PJ04@976|Bacteroidetes,2FQGB@200643|Bacteroidia,4AMAJ@815|Bacteroidaceae	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS3_k127_6601429_1	886293.Sinac_6796	1.03e-102	357.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CMS3_k127_6601429_0	247490.KSU1_C0075	1.146e-186	629.0	COG1196@1|root,COG1196@2|Bacteria,2IY32@203682|Planctomycetes	203682|Planctomycetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS3_k127_6601429_2	1121918.ARWE01000001_gene1118	3.121e-24	115.0	COG0834@1|root,COG2204@1|root,COG3852@1|root,COG0834@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,1N315@1224|Proteobacteria	1224|Proteobacteria	T	Extracellular solute-binding protein family 3	-	-	2.7.13.3	ko:K07679	ko02020,ko05133,map02020,map05133	M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_6630339_0	234267.Acid_4940	6.008e-39	165.0	COG1409@1|root,COG1657@1|root,COG4412@1|root,COG1409@2|Bacteria,COG1657@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K14647,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	CARDB,Peptidase_M30
CMS3_k127_663506_12	1396141.BATP01000019_gene1580	8.209e-23	110.0	COG0526@1|root,COG0526@2|Bacteria,46VHM@74201|Verrucomicrobia,2IVZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_663506_8	1408473.JHXO01000007_gene758	6.721e-38	151.0	COG0546@1|root,COG0546@2|Bacteria,4NIJ1@976|Bacteroidetes,2G32Q@200643|Bacteroidia	976|Bacteroidetes	S	HAD hydrolase, family IA, variant	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_663506_13	243265.plu2783	1.317e-22	99.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_663506_9	886293.Sinac_4712	2.982e-30	130.0	COG2353@1|root,COG2353@2|Bacteria,2J1I0@203682|Planctomycetes	203682|Planctomycetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_663506_7	1121920.AUAU01000012_gene2647	3.033e-45	183.0	COG4191@1|root,COG4191@2|Bacteria,3Y42C@57723|Acidobacteria	57723|Acidobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_663506_6	886293.Sinac_2556	3.933e-62	228.0	COG0526@1|root,COG1331@1|root,COG0526@2|Bacteria,COG1331@2|Bacteria,2J28Y@203682|Planctomycetes	203682|Planctomycetes	CO	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_663506_3	1118054.CAGW01000060_gene2572	2.942e-75	269.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,26SAK@186822|Paenibacillaceae	91061|Bacilli	V	ABC-type antimicrobial peptide transport system, permease component	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_663506_5	1303518.CCALI_02700	3.533e-68	247.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_663506_10	768706.Desor_5285	6.386e-25	119.0	COG0845@1|root,COG0845@2|Bacteria,1UY0S@1239|Firmicutes,25CIV@186801|Clostridia,260HX@186807|Peptococcaceae	186801|Clostridia	M	Secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
CMS3_k127_663506_0	1123508.JH636439_gene704	4.752e-154	496.0	COG0686@1|root,COG0686@2|Bacteria,2IXPP@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_663506_4	1210884.HG799465_gene11364	3.03e-75	283.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2IY17@203682|Planctomycetes	203682|Planctomycetes	S	competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_663506_2	1123242.JH636435_gene2473	3.802e-78	278.0	COG1215@1|root,COG1215@2|Bacteria,2J02Q@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_663506_1	756272.Plabr_2180	4.324e-96	327.0	COG1657@1|root,COG1657@2|Bacteria,2IXAS@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
CMS3_k127_663506_11	323259.Mhun_3130	2.693e-24	113.0	COG1404@1|root,COG3291@1|root,arCOG02516@1|root,arCOG03264@1|root,arCOG00702@2157|Archaea,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG03264@2157|Archaea,2XYB3@28890|Euryarchaeota,2NBHC@224756|Methanomicrobia	2157|Archaea	O	Papain family cysteine protease	-	-	-	ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PEGA,PKD,Peptidase_S8
CMS3_k127_6649133_11	1499967.BAYZ01000081_gene1059	8.231e-45	173.0	COG1215@1|root,COG1215@2|Bacteria,2NQN7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_6649133_9	886293.Sinac_5694	7.027e-62	235.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6649133_3	234267.Acid_4641	3.323e-102	351.0	COG1134@1|root,COG1134@2|Bacteria,3Y756@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_6649133_5	234267.Acid_4640	9.669e-86	291.0	COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_6649133_7	351016.RAZWK3B_00900	1.208e-70	253.0	COG0438@1|root,COG0438@2|Bacteria,1RAXB@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS3_k127_6649133_13	1137271.AZUM01000008_gene1997	0.0003862	51.0	COG4122@1|root,COG4122@2|Bacteria,2IC8Z@201174|Actinobacteria,4E3SY@85010|Pseudonocardiales	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS3_k127_6649133_6	41431.PCC8801_3881	1.623e-76	268.0	COG1215@1|root,COG1215@2|Bacteria,1GPZX@1117|Cyanobacteria,3KIWW@43988|Cyanothece	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6649133_4	1487953.JMKF01000021_gene2201	1.677e-94	320.0	COG1215@1|root,COG1215@2|Bacteria,1GPZX@1117|Cyanobacteria,1HCD3@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6649133_10	357808.RoseRS_2382	1.178e-59	223.0	COG1216@1|root,COG1216@2|Bacteria,2GB2A@200795|Chloroflexi,377SM@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6649133_8	247490.KSU1_C1702	1.952e-68	249.0	COG0438@1|root,COG0438@2|Bacteria,2IY70@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_6649133_2	357808.RoseRS_2391	6.746e-123	406.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Acyltransferase,MMPL,Methyltransf_13,Methyltransf_14,Methyltransf_23,Methyltransf_31
CMS3_k127_6649133_1	118163.Ple7327_1366	1.981e-138	454.0	COG2227@1|root,COG2227@2|Bacteria,1G1XD@1117|Cyanobacteria,3VI2X@52604|Pleurocapsales	1117|Cyanobacteria	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_14,Methyltransf_23
CMS3_k127_6649133_0	1499967.BAYZ01000104_gene3698	1.195e-173	553.0	COG2227@1|root,COG2227@2|Bacteria,2NQQ9@2323|unclassified Bacteria	2|Bacteria	H	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
CMS3_k127_6649133_12	696747.NIES39_O05240	1.815e-44	164.0	COG0451@1|root,COG0451@2|Bacteria,1G3FQ@1117|Cyanobacteria,1H989@1150|Oscillatoriales	1117|Cyanobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_6660976_0	1499967.BAYZ01000173_gene5813	1.581e-126	422.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
CMS3_k127_67289_5	234267.Acid_7187	1.061e-108	375.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_67289_11	765910.MARPU_14505	4.202e-33	142.0	COG1215@1|root,COG1215@2|Bacteria,1QXFV@1224|Proteobacteria,1T599@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_67289_3	234267.Acid_7187	2.897e-112	390.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_67289_4	234267.Acid_7187	4.749e-110	383.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_67289_9	243090.RB8770	8.428e-75	273.0	COG0330@1|root,COG0330@2|Bacteria,2IXS2@203682|Planctomycetes	203682|Planctomycetes	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_67289_8	243090.RB8773	2.489e-76	276.0	COG0330@1|root,COG0330@2|Bacteria,2IYPR@203682|Planctomycetes	203682|Planctomycetes	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_67289_7	1123242.JH636436_gene755	1.555e-77	271.0	COG4974@1|root,COG4974@2|Bacteria,2IX6A@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_67289_18	1210884.HG799466_gene12546	8.93e-05	47.0	2E3N9@1|root,33M91@2|Bacteria,2J1E4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_67289_14	1142394.PSMK_28220	3.725e-15	85.0	COG3170@1|root,COG3170@2|Bacteria,2IZYK@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_67289_6	1142394.PSMK_28230	2.004e-80	285.0	COG0823@1|root,COG0823@2|Bacteria,2IXGY@203682|Planctomycetes	203682|Planctomycetes	U	Periplasmic component of the Tol biopolymer transport	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,PDZ_2,Peptidase_M28
CMS3_k127_67289_15	234267.Acid_4520	1.084e-14	84.0	COG1335@1|root,COG1335@2|Bacteria,3Y7ZP@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
CMS3_k127_67289_12	886293.Sinac_5067	1.225e-17	87.0	COG1145@1|root,COG1145@2|Bacteria,2IZZ5@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S binding domain	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	Fer4
CMS3_k127_67289_13	1313301.AUGC01000005_gene358	4.613e-16	81.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes	976|Bacteroidetes	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ccmG	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
CMS3_k127_67289_16	435591.BDI_0229	1.25e-06	59.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FM3J@200643|Bacteroidia,231UD@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369
CMS3_k127_67289_1	521674.Plim_3208	4.665e-122	413.0	COG0405@1|root,COG0405@2|Bacteria,2IWWP@203682|Planctomycetes	203682|Planctomycetes	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_67289_0	1121430.JMLG01000005_gene717	3.095e-133	448.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,260IK@186807|Peptococcaceae	186801|Clostridia	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
CMS3_k127_67289_2	1120973.AQXL01000135_gene1361	2.524e-120	404.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HAAC@91061|Bacilli,279IC@186823|Alicyclobacillaceae	91061|Bacilli	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS3_k127_67289_10	1142394.PSMK_30020	7.807e-67	248.0	COG1192@1|root,COG3170@1|root,COG1192@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496,ko:K09000	-	-	-	-	ko00000,ko02048,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_6736724_0	118168.MC7420_5234	4.136e-80	287.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6761937_4	502025.Hoch_0991	1.007e-21	95.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
CMS3_k127_6761937_3	344747.PM8797T_11434	1.114e-27	121.0	COG3436@1|root,COG3436@2|Bacteria,2J11P@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
CMS3_k127_6761937_1	1210884.HG799462_gene9225	8.069e-146	480.0	COG3316@1|root,COG3316@2|Bacteria,2J4XX@203682|Planctomycetes	203682|Planctomycetes	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
CMS3_k127_6761937_0	314230.DSM3645_15625	7.29e-249	782.0	COG4147@1|root,COG4147@2|Bacteria,2IX2N@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS3_k127_6761937_2	1449357.JQLK01000001_gene2141	6.838e-28	117.0	COG4327@1|root,COG4327@2|Bacteria,1WK88@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	solute sodium symporter small subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
CMS3_k127_6762538_0	1210884.HG799466_gene12912	1.549e-31	127.0	2E7TZ@1|root,33290@2|Bacteria,2J410@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6772469_1	1265502.KB905956_gene116	1.449e-17	82.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,4AC3H@80864|Comamonadaceae	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS3_k127_6772469_0	243233.MCA2375	1.273e-287	892.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1XDNZ@135618|Methylococcales	135618|Methylococcales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_6778336_0	443598.AUFA01000017_gene7352	2.42e-08	65.0	2A6EI@1|root,30V7D@2|Bacteria,1R7V1@1224|Proteobacteria,2U338@28211|Alphaproteobacteria,3JW4K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6791500_4	234267.Acid_4431	6.443e-35	148.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_6791500_5	234267.Acid_5940	4.237e-32	132.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6791500_1	1191523.MROS_0904	1.481e-69	248.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.6.1.13	ko:K01771	ko00562,map00562	-	R03332	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PD40,PI-PLC-X
CMS3_k127_6791500_3	313603.FB2170_04395	7.592e-38	148.0	2DM9Y@1|root,32AJ6@2|Bacteria,4NQQC@976|Bacteroidetes,1I336@117743|Flavobacteriia,2PHFY@252356|Maribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6791500_6	713586.KB900536_gene2315	3.681e-21	98.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Flavin and coenzyme A sequestration protein dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS3_k127_6791500_0	1282362.AEAC466_18080	1.212e-84	298.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria,2KFJX@204458|Caulobacterales	204458|Caulobacterales	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
CMS3_k127_6791500_7	521674.Plim_0125	6.446e-05	47.0	COG2318@1|root,COG2318@2|Bacteria,2J0AU@203682|Planctomycetes	203682|Planctomycetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_6791500_2	448385.sce6861	1.683e-43	164.0	2DQ41@1|root,334MP@2|Bacteria,1QWJG@1224|Proteobacteria,43CUB@68525|delta/epsilon subdivisions,2X81Y@28221|Deltaproteobacteria,2Z1U1@29|Myxococcales	1224|Proteobacteria	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1
CMS3_k127_6802616_19	1227739.Hsw_3527	1.026e-21	95.0	COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.5	ko:K15067	ko00380,map00380	-	R03887	RC01015	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
CMS3_k127_6802616_14	1489678.RDMS_03040	4.979e-47	177.0	COG1878@1|root,COG1878@2|Bacteria,1WJZU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
CMS3_k127_6802616_8	1210884.HG799476_gene15392	5.135e-111	364.0	COG3483@1|root,COG3483@2|Bacteria,2J412@203682|Planctomycetes	203682|Planctomycetes	E	Tryptophan 2,3-dioxygenase	-	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CMS3_k127_6802616_2	1121920.AUAU01000017_gene1239	1.899e-182	593.0	COG0281@1|root,COG0281@2|Bacteria,3Y43V@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
CMS3_k127_6802616_18	1121396.KB893077_gene737	3.123e-24	113.0	COG1102@1|root,COG1102@2|Bacteria,1RGPZ@1224|Proteobacteria,42YH5@68525|delta/epsilon subdivisions,2WTYH@28221|Deltaproteobacteria,2MMHV@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
CMS3_k127_6802616_5	118163.Ple7327_2009	1.098e-119	393.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,3VJ02@52604|Pleurocapsales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_6802616_0	1125863.JAFN01000001_gene663	0.0	1620.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_6802616_3	1125863.JAFN01000001_gene1528	1.382e-148	483.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6802616_10	290397.Adeh_1329	2.466e-59	226.0	COG0642@1|root,COG2205@2|Bacteria,1QX6V@1224|Proteobacteria,43AID@68525|delta/epsilon subdivisions,2X5YM@28221|Deltaproteobacteria,2YUUS@29|Myxococcales	28221|Deltaproteobacteria	T	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Protoglobin
CMS3_k127_6802616_24	1232410.KI421428_gene1054	0.0004899	49.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6802616_21	477974.Daud_2208	1.946e-17	94.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,24I2P@186801|Clostridia,261WS@186807|Peptococcaceae	186801|Clostridia	S	PFAM CBS domain	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
CMS3_k127_6802616_15	1408224.SAMCCGM7_c6068	1.162e-38	153.0	COG2836@1|root,COG2836@2|Bacteria	2|Bacteria	K	Biogenesis protein	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	Cupredoxin_1,DsbD_2,Ferric_reduct,HMA
CMS3_k127_6802616_22	530564.Psta_3510	4.475e-08	55.0	2ER4N@1|root,33IQ6@2|Bacteria,2J18T@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6802616_20	530564.Psta_3511	2.405e-19	92.0	2ERHY@1|root,33J3E@2|Bacteria,2J1MJ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6802616_9	575540.Isop_0562	7.839e-72	249.0	COG2993@1|root,COG2993@2|Bacteria,2IYKY@203682|Planctomycetes	203682|Planctomycetes	C	PFAM cytochrome C oxidase mono-heme subunit FixO	-	-	-	-	-	-	-	-	-	-	-	-	FixO
CMS3_k127_6802616_1	1123242.JH636434_gene5036	1.79e-203	642.0	COG3278@1|root,COG3278@2|Bacteria,2IY0E@203682|Planctomycetes	203682|Planctomycetes	C	COGs COG3278 Cbb3-type cytochrome oxidase subunit 1	-	-	1.9.3.1	ko:K00404,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
CMS3_k127_6802616_12	404589.Anae109_2859	3.033e-55	209.0	COG2010@1|root,COG2010@2|Bacteria,1R03D@1224|Proteobacteria,43CQJ@68525|delta/epsilon subdivisions,2X7Y0@28221|Deltaproteobacteria,2Z1XC@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_6802616_13	1123242.JH636434_gene5035	3.66e-52	191.0	2E21C@1|root,32X94@2|Bacteria,2J0HY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6802616_6	880073.Calab_3508	1.912e-118	391.0	COG1446@1|root,COG1446@2|Bacteria,2NPFC@2323|unclassified Bacteria	2|Bacteria	E	Asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
CMS3_k127_6802616_16	585530.HMPREF0183_0160	3.293e-27	120.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4FA77@85019|Brevibacteriaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS3_k127_6802616_11	290317.Cpha266_1159	6.682e-59	212.0	COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS3_k127_6802616_7	1121468.AUBR01000026_gene2952	5.526e-116	387.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,42F1H@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS3_k127_6802616_23	751944.HALDL1_12990	2.397e-05	49.0	arCOG07584@1|root,arCOG07584@2157|Archaea,2Y18A@28890|Euryarchaeota,23YCD@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6802616_4	401526.TcarDRAFT_2500	2.124e-132	442.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H43N@909932|Negativicutes	909932|Negativicutes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_6802616_17	471853.Bcav_2774	5.648e-25	111.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS3_k127_6818173_18	1122921.KB898188_gene271	7.319e-06	55.0	28IKZ@1|root,2Z8MJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1702)	-	-	-	ko:K21161	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	DUF1702
CMS3_k127_6818173_3	1121878.AUGL01000005_gene2442	2.911e-53	215.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_6818173_10	595460.RRSWK_05503	1.899e-26	128.0	COG1572@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG3420@1|root,COG4257@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG4257@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818173_14	1122179.KB890422_gene2240	8.301e-13	83.0	COG2931@1|root,COG3227@1|root,COG3292@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3292@2|Bacteria,4NHTI@976|Bacteroidetes	976|Bacteroidetes	T	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	CUB,Pep_M12B_propep,Reprolysin_5
CMS3_k127_6818173_8	1379698.RBG1_1C00001G1377	4.115e-29	136.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
CMS3_k127_6818173_13	314230.DSM3645_01771	3.68e-18	93.0	2EC0X@1|root,33605@2|Bacteria,2J0WR@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818173_16	862908.BMS_3187	7.916e-07	61.0	2EEQZ@1|root,338IP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818173_5	1200557.JHWV01000005_gene1526	2.141e-39	156.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,4H3AU@909932|Negativicutes	909932|Negativicutes	N	flagellar basal-body rod protein	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS3_k127_6818173_1	1142394.PSMK_26610	5.208e-84	286.0	COG4786@1|root,COG4786@2|Bacteria,2IXW0@203682|Planctomycetes	203682|Planctomycetes	N	Flagellar basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CMS3_k127_6818173_15	1056820.KB900696_gene4061	3.836e-10	72.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,1S8SQ@1236|Gammaproteobacteria,2PP2V@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NO	Chaperone for flagella basal body P-ring formation	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
CMS3_k127_6818173_9	595460.RRSWK_05667	1.038e-27	122.0	COG2063@1|root,COG2063@2|Bacteria,2IZXJ@203682|Planctomycetes	203682|Planctomycetes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
CMS3_k127_6818173_4	344747.PM8797T_04935	8.581e-46	180.0	COG1706@1|root,COG1706@2|Bacteria,2IZDW@203682|Planctomycetes	203682|Planctomycetes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
CMS3_k127_6818173_17	314230.DSM3645_08447	8.589e-07	57.0	2CCRK@1|root,33351@2|Bacteria,2J0NN@203682|Planctomycetes	203682|Planctomycetes	S	Rod binding protein	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Rod-binding
CMS3_k127_6818173_7	1142394.PSMK_01540	8.324e-31	126.0	COG1699@1|root,COG1699@2|Bacteria,2J04H@203682|Planctomycetes	203682|Planctomycetes	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
CMS3_k127_6818173_11	886293.Sinac_6711	6.285e-22	100.0	COG1551@1|root,COG1551@2|Bacteria,2J0YE@203682|Planctomycetes	203682|Planctomycetes	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
CMS3_k127_6818173_2	756272.Plabr_1542	3.608e-56	203.0	COG0590@1|root,COG0590@2|Bacteria,2IZCA@203682|Planctomycetes	203682|Planctomycetes	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
CMS3_k127_6818173_6	1216976.AX27061_2935	1.638e-38	149.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_6818173_0	1192034.CAP_8119	5.616e-107	377.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
CMS3_k127_6818173_19	1262449.CP6013_0770	0.0008504	53.0	COG0457@1|root,COG3266@1|root,COG4676@1|root,COG4870@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,COG4676@2|Bacteria,COG4870@2|Bacteria,1VDA3@1239|Firmicutes	1239|Firmicutes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Flg_new,TPR_19
CMS3_k127_6818173_12	502025.Hoch_6539	6e-21	104.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6825550_2	382464.ABSI01000010_gene3722	1.199e-56	213.0	COG1028@1|root,COG1028@2|Bacteria	382464.ABSI01000010_gene3722|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6825550_0	448385.sce7105	3.081e-121	403.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_6825550_6	794903.OPIT5_07550	9.813e-09	66.0	COG2165@1|root,COG2165@2|Bacteria,46Y0Z@74201|Verrucomicrobia,3K8RM@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS3_k127_6825550_5	1128421.JAGA01000003_gene3523	4.884e-13	83.0	COG0318@1|root,COG0318@2|Bacteria,2NR5F@2323|unclassified Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	MA20_41400	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6825550_1	886293.Sinac_0578	1.115e-108	360.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6825550_3	314230.DSM3645_16540	2.847e-28	132.0	COG1668@1|root,COG1668@2|Bacteria,2IXFE@203682|Planctomycetes	203682|Planctomycetes	CP	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS3_k127_6825550_4	1500894.JQNN01000001_gene1991	2.197e-17	96.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VWW5@28216|Betaproteobacteria,477YT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS3_k127_6825928_0	886293.Sinac_2617	1.332e-112	391.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
CMS3_k127_6825928_1	383372.Rcas_3818	4.553e-111	368.0	COG0714@1|root,COG0714@2|Bacteria,2GACN@200795|Chloroflexi,375BZ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_6825928_2	886293.Sinac_2614	7.229e-108	358.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_6825928_3	314230.DSM3645_08647	9.866e-82	298.0	COG2304@1|root,COG2304@2|Bacteria,2IXP0@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_6825928_4	1192124.LIG30_0630	3.675e-09	68.0	COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2VJZ8@28216|Betaproteobacteria,1JZX4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Oxidoreductase domain protein	-	-	1.1.1.18,1.1.1.369,1.3.1.64	ko:K00010,ko:K18067	ko00521,ko00562,ko00624,ko01100,ko01120,ko01130,ko01220,map00521,map00562,map00624,map01100,map01120,map01130,map01220	M00623	R01183,R05275,R09951	RC00182,RC00386	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_6830582_2	1163409.UUA_02756	1.946e-09	61.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
CMS3_k127_6830582_0	237368.SCABRO_00218	4.942e-159	522.0	COG0367@1|root,COG0367@2|Bacteria,2IXAI@203682|Planctomycetes	203682|Planctomycetes	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_6830582_1	886293.Sinac_6462	5.699e-110	364.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_6853502_3	562970.Btus_2586	1.766e-52	194.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,4HTP0@91061|Bacilli,279M4@186823|Alicyclobacillaceae	91061|Bacilli	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_6853502_2	1142394.PSMK_28670	1.102e-75	267.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	mdsC	-	2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Glyco_hydro_63
CMS3_k127_6853502_5	1142394.PSMK_02820	1.965e-29	121.0	COG0799@1|root,COG0799@2|Bacteria,2J0AM@203682|Planctomycetes	203682|Planctomycetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS3_k127_6853502_1	240292.Ava_3561	5.83e-176	571.0	COG0018@1|root,COG0018@2|Bacteria,1G15V@1117|Cyanobacteria,1HKCG@1161|Nostocales	1117|Cyanobacteria	J	TIGRFAM Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS3_k127_6853502_7	551115.Aazo_5173	5.36e-07	60.0	COG0238@1|root,COG0238@2|Bacteria,1G7NE@1117|Cyanobacteria,1HPIK@1161|Nostocales	1117|Cyanobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS3_k127_6853502_6	395493.BegalDRAFT_2694	5.093e-08	59.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,1SCFF@1236|Gammaproteobacteria,461BT@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
CMS3_k127_6853502_0	530564.Psta_2259	0.0	1214.0	COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_6853502_4	472759.Nhal_1087	1.272e-30	129.0	COG0737@1|root,COG0737@2|Bacteria,1RFNB@1224|Proteobacteria	1224|Proteobacteria	C	oxidation-reduction process	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_6870932_0	314264.ROS217_02330	3.315e-104	353.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,46Q9A@74030|Roseovarius	28211|Alphaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_6870932_1	1380391.JIAS01000013_gene3476	3.856e-08	59.0	COG3909@1|root,COG3909@2|Bacteria,1N6Z5@1224|Proteobacteria,2VBN2@28211|Alphaproteobacteria,2JUDU@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C'	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
CMS3_k127_6873682_10	349741.Amuc_1060	4.68e-12	77.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
CMS3_k127_6873682_0	349741.Amuc_1059	5.333e-256	824.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,2ITM5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
CMS3_k127_6873682_4	1142394.PSMK_01400	2.116e-115	383.0	COG0150@1|root,COG0150@2|Bacteria,2IYCG@203682|Planctomycetes	203682|Planctomycetes	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_6873682_2	237368.SCABRO_01933	2.625e-146	480.0	COG0034@1|root,COG0034@2|Bacteria,2IXKC@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS3_k127_6873682_5	1144275.COCOR_06368	9.725e-89	310.0	COG4552@1|root,COG4552@2|Bacteria,1NBTH@1224|Proteobacteria,42W5G@68525|delta/epsilon subdivisions,2WXK2@28221|Deltaproteobacteria,2YW0Z@29|Myxococcales	28221|Deltaproteobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
CMS3_k127_6873682_3	382464.ABSI01000010_gene3269	2.232e-119	396.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	doeB	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS3_k127_6873682_1	756272.Plabr_2643	1.309e-147	479.0	COG0189@1|root,COG0490@1|root,COG0189@2|Bacteria,COG0490@2|Bacteria,2IYT1@203682|Planctomycetes	203682|Planctomycetes	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,TrkA_C
CMS3_k127_6873682_8	314230.DSM3645_21724	8.971e-34	141.0	COG4067@1|root,COG4067@2|Bacteria,2J12V@203682|Planctomycetes	203682|Planctomycetes	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS3_k127_6873682_9	1142394.PSMK_06260	1.683e-25	119.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_6873682_7	756272.Plabr_0502	5.104e-49	192.0	COG2206@1|root,COG2206@2|Bacteria,2J3G2@203682|Planctomycetes	203682|Planctomycetes	T	COG2206 HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
CMS3_k127_6873682_6	234267.Acid_4278	5.525e-53	203.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
CMS3_k127_6901175_0	530564.Psta_3696	2.359e-138	460.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,zf-IS66
CMS3_k127_6901175_1	314230.DSM3645_28137	4.436e-31	131.0	COG3436@1|root,COG3436@2|Bacteria,2J11P@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
CMS3_k127_6924428_4	555088.DealDRAFT_2759	4.206e-67	238.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,25KAP@186801|Clostridia,42KJ1@68298|Syntrophomonadaceae	186801|Clostridia	P	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6924428_0	644966.Tmar_0917	1.213e-146	492.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WCFK@538999|Clostridiales incertae sedis	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS3_k127_6924428_3	349124.Hhal_0672	2.915e-81	284.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1WWZ4@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS3_k127_6924428_11	314230.DSM3645_07066	1.792e-14	81.0	2DSSH@1|root,33H9S@2|Bacteria,2J1GW@203682|Planctomycetes	203682|Planctomycetes	L	DNA polymerase Ligase (LigD)	-	-	-	-	-	-	-	-	-	-	-	-	LigD_N
CMS3_k127_6924428_13	1122970.AUHC01000005_gene2040	6.771e-05	53.0	COG0457@1|root,COG0457@2|Bacteria,1QNIE@1224|Proteobacteria,2TVQA@28211|Alphaproteobacteria,2K08T@204457|Sphingomonadales	204457|Sphingomonadales	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_19
CMS3_k127_6924428_10	1034345.CAEM01000017_gene1617	3.402e-19	98.0	COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS3_k127_6924428_1	1121335.Clst_0180	9.71e-91	312.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_6924428_7	647113.Metok_1036	4.055e-46	190.0	COG0642@1|root,arCOG02322@1|root,arCOG02322@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,23RVT@183939|Methanococci	183939|Methanococci	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
CMS3_k127_6924428_9	290400.Jann_2695	2.104e-22	102.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	tcrX	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_6924428_5	370438.PTH_1596	3.726e-61	229.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,261QQ@186807|Peptococcaceae	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD
CMS3_k127_6924428_2	1047013.AQSP01000139_gene2416	1.417e-82	302.0	COG1404@1|root,COG1404@2|Bacteria,2NNSK@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_6924428_8	1142394.PSMK_25320	1.898e-28	129.0	COG1216@1|root,COG1216@2|Bacteria,2J4DP@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6924428_6	1410665.JNKR01000005_gene1593	1.896e-49	184.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4H2AC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_6924428_12	671143.DAMO_0317	4.44e-08	64.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,CBM_35,DUF1080,PKD
CMS3_k127_6936642_6	1535422.ND16A_2156	4.462e-146	518.0	COG1800@1|root,COG5184@1|root,COG1800@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_5,CHU_C,CW_binding_2,Cadherin-like,CarboxypepD_reg,Laminin_G_3,SLH
CMS3_k127_6936642_9	909663.KI867150_gene1321	2.53e-70	251.0	COG0500@1|root,COG1846@1|root,COG1846@2|Bacteria,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,43BRY@68525|delta/epsilon subdivisions,2X72R@28221|Deltaproteobacteria,2MQCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	KQ	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS3_k127_6936642_7	1232437.KL661958_gene2890	1.76e-89	301.0	COG1034@1|root,COG1034@2|Bacteria,1RK80@1224|Proteobacteria,43CTD@68525|delta/epsilon subdivisions,2X80Y@28221|Deltaproteobacteria,2MPQ2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7
CMS3_k127_6936642_2	1232437.KL661958_gene2889	0.0	1017.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MJ8N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	bamH	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_2080	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CMS3_k127_6936642_10	706587.Desti_1917	9.588e-66	229.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,43B7N@68525|delta/epsilon subdivisions,2X6M3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
CMS3_k127_6936642_8	1232437.KL661958_gene2887	4.222e-81	276.0	COG1414@1|root,COG1908@1|root,COG1414@2|Bacteria,COG1908@2|Bacteria,1R93S@1224|Proteobacteria,42QKE@68525|delta/epsilon subdivisions,2WMF5@28221|Deltaproteobacteria,2MK99@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,FlpD
CMS3_k127_6936642_0	706587.Desti_1915	0.0	1394.0	COG1148@1|root,COG1149@1|root,COG1148@2|Bacteria,COG1149@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
CMS3_k127_6936642_13	56780.SYN_01644	1.874e-27	112.0	COG1148@1|root,COG1148@2|Bacteria,1P24T@1224|Proteobacteria,431A0@68525|delta/epsilon subdivisions,2WWJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS3_k127_6936642_4	1121405.dsmv_2374	9.508e-172	547.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MJHX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
CMS3_k127_6936642_11	1232410.KI421423_gene1923	2.458e-49	181.0	COG1142@1|root,COG1142@2|Bacteria,1RBG7@1224|Proteobacteria,42R5G@68525|delta/epsilon subdivisions,2WMV5@28221|Deltaproteobacteria,43U2T@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K19516	ko00362,ko01100,ko01120,map00362,map01100,map01120	M00541	R10961	RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS3_k127_6936642_1	1121405.dsmv_2380	0.0	1095.0	COG2414@1|root,COG2414@2|Bacteria,1R955@1224|Proteobacteria,42NN4@68525|delta/epsilon subdivisions,2WJEQ@28221|Deltaproteobacteria,2MMX0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	bamB-2	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS3_k127_6936642_3	767817.Desgi_3838	6.174e-177	561.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_6936642_12	1379698.RBG1_1C00001G0893	4.83e-46	174.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
CMS3_k127_6936642_5	234267.Acid_5749	8.707e-148	502.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_6943904_8	756499.Desde_0834	1.369e-60	214.0	2EUF4@1|root,33MXE@2|Bacteria,1VZNU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6943904_11	682795.AciX8_1298	9.925e-43	161.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS3_k127_6943904_9	595460.RRSWK_04882	9.23e-57	212.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_6943904_14	290397.Adeh_0228	1.865e-30	128.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,42WUF@68525|delta/epsilon subdivisions,2WSZU@28221|Deltaproteobacteria,2Z1PT@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6943904_2	1205680.CAKO01000038_gene1920	6.415e-85	289.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,2JU60@204441|Rhodospirillales	204441|Rhodospirillales	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_6943904_6	102125.Xen7305DRAFT_00021900	4.012e-66	231.0	COG1765@1|root,COG1765@2|Bacteria,1GAGW@1117|Cyanobacteria,3VN97@52604|Pleurocapsales	1117|Cyanobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_6943904_12	439235.Dalk_1835	4.053e-40	158.0	COG4843@1|root,COG4843@2|Bacteria,1REIP@1224|Proteobacteria,42S29@68525|delta/epsilon subdivisions,2WNWG@28221|Deltaproteobacteria,2MKCT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
CMS3_k127_6943904_15	1192034.CAP_7488	3.312e-15	91.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
CMS3_k127_6943904_7	502025.Hoch_0873	4.506e-61	243.0	COG1075@1|root,COG5492@1|root,COG1075@2|Bacteria,COG5492@2|Bacteria,1P60C@1224|Proteobacteria,4395U@68525|delta/epsilon subdivisions,2X4CF@28221|Deltaproteobacteria,2YYRC@29|Myxococcales	28221|Deltaproteobacteria	N	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
CMS3_k127_6943904_16	1408164.MOLA814_00773	1.892e-11	72.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6943904_4	1089550.ATTH01000001_gene1831	2.561e-78	291.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
CMS3_k127_6943904_17	45351.EDO42283	3.873e-11	72.0	KOG3649@1|root,KOG3649@2759|Eukaryota,39TKW@33154|Opisthokonta,3BKG3@33208|Metazoa	33208|Metazoa	S	Kazal-type serine protease inhibitor domain	-	GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0008150,GO:0009719,GO:0009725,GO:0009892,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0014070,GO:0019222,GO:0019863,GO:0019864,GO:0019865,GO:0030162,GO:0030234,GO:0030246,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0032991,GO:0033993,GO:0042221,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044092,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045861,GO:0048519,GO:0048523,GO:0048545,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772	-	-	-	-	-	-	-	-	-	-	Kazal_1
CMS3_k127_6943904_19	768710.DesyoDRAFT_3885	3.922e-08	61.0	COG1051@1|root,COG1051@2|Bacteria,1UIGB@1239|Firmicutes,24NCA@186801|Clostridia,262AE@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_6943904_13	886293.Sinac_5873	2.985e-38	154.0	COG1595@1|root,COG1595@2|Bacteria,2J08Y@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6943904_10	290397.Adeh_0155	2.23e-50	191.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42SU3@68525|delta/epsilon subdivisions,2WP9X@28221|Deltaproteobacteria,2YVJF@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
CMS3_k127_6943904_0	1463845.JOIG01000009_gene2820	3.206e-225	706.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS3_k127_6943904_18	1254432.SCE1572_22375	4.773e-10	74.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6943904_5	10224.XP_006812373.1	5.952e-67	259.0	COG2866@1|root,KOG2650@2759|Eukaryota,38DUK@33154|Opisthokonta,3BA6U@33208|Metazoa,3CUQS@33213|Bilateria	33208|Metazoa	O	metallocarboxypeptidase activity	CPB2	GO:0001678,GO:0001889,GO:0001990,GO:0001991,GO:0002002,GO:0002003,GO:0002673,GO:0002682,GO:0002697,GO:0002920,GO:0003008,GO:0003013,GO:0003044,GO:0003073,GO:0003081,GO:0003330,GO:0003331,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006325,GO:0006464,GO:0006473,GO:0006475,GO:0006508,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007039,GO:0007275,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008285,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009743,GO:0009746,GO:0009749,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0010755,GO:0010757,GO:0010817,GO:0010955,GO:0012505,GO:0016043,GO:0016485,GO:0016486,GO:0016569,GO:0016570,GO:0016573,GO:0016787,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019222,GO:0019538,GO:0019725,GO:0022603,GO:0030133,GO:0030141,GO:0030162,GO:0030163,GO:0030193,GO:0030194,GO:0030195,GO:0030449,GO:0031012,GO:0031099,GO:0031100,GO:0031323,GO:0031324,GO:0031347,GO:0031410,GO:0031982,GO:0032101,GO:0032102,GO:0032103,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0033500,GO:0034284,GO:0034641,GO:0036211,GO:0042127,GO:0042221,GO:0042445,GO:0042493,GO:0042592,GO:0042593,GO:0042730,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043412,GO:0043543,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045861,GO:0046872,GO:0046914,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0048878,GO:0050678,GO:0050680,GO:0050727,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050818,GO:0050819,GO:0050820,GO:0050878,GO:0050886,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051276,GO:0051603,GO:0051604,GO:0051716,GO:0051917,GO:0051918,GO:0055082,GO:0060102,GO:0060255,GO:0061008,GO:0061041,GO:0061045,GO:0062023,GO:0065007,GO:0065008,GO:0070011,GO:0070613,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0090303,GO:0097421,GO:0097708,GO:0099503,GO:0140096,GO:1900046,GO:1900047,GO:1900048,GO:1901564,GO:1901565,GO:1901575,GO:1901700,GO:1901701,GO:1903034,GO:1903035,GO:1903036,GO:1903053,GO:1903055,GO:1903317,GO:1903318,GO:1903530,GO:1903532,GO:2000026,GO:2000027,GO:2000257,GO:2000345,GO:2000346	3.4.17.1,3.4.17.15,3.4.17.2,3.4.17.20	ko:K01291,ko:K01298,ko:K01300,ko:K08637,ko:K08779,ko:K08780,ko:K08781	ko04610,ko04614,ko04972,ko04974,map04610,map04614,map04972,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_M14,Propep_M14
CMS3_k127_6943904_3	1515746.HR45_11315	2.045e-82	303.0	COG3303@1|root,COG3303@2|Bacteria,1NNDS@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6943904_1	219305.MCAG_05245	6.07e-137	441.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DAXK@85008|Micromonosporales	201174|Actinobacteria	EK	Cystathionine beta-synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_6954084_5	756272.Plabr_1439	1.242e-23	102.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2IXQR@203682|Planctomycetes	203682|Planctomycetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS3_k127_6954084_3	1122917.KB899672_gene765	4.535e-56	208.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,4HEED@91061|Bacilli,26QWA@186822|Paenibacillaceae	91061|Bacilli	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS3_k127_6954084_0	448385.sce5027	1.078e-217	681.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS3_k127_6954084_2	525904.Tter_0037	2.071e-70	246.0	COG0175@1|root,COG0175@2|Bacteria,2NPHM@2323|unclassified Bacteria	2|Bacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15570	PAPS_reduct
CMS3_k127_6954084_1	1382306.JNIM01000001_gene2462	1.145e-183	592.0	COG0155@1|root,COG0155@2|Bacteria,2G7ZA@200795|Chloroflexi	200795|Chloroflexi	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS3_k127_6954084_4	479434.Sthe_1800	1.893e-41	169.0	COG0373@1|root,COG0373@2|Bacteria,2G5T4@200795|Chloroflexi,27YFY@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_6954084_7	1122135.KB893166_gene3063	4.011e-15	85.0	COG2138@1|root,COG2138@2|Bacteria,1RJC9@1224|Proteobacteria	1224|Proteobacteria	S	Cobalamin (Vitamin B12) biosynthesis CbiX protein	cbiX	-	-	-	-	-	-	-	-	-	-	-	CbiX
CMS3_k127_6954084_6	1382306.JNIM01000001_gene2460	1.078e-19	91.0	COG0007@1|root,COG0007@2|Bacteria,2G6EG@200795|Chloroflexi	200795|Chloroflexi	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
CMS3_k127_6978444_1	234267.Acid_5749	2.069e-158	530.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_6978444_2	234267.Acid_0873	2.235e-145	488.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y6VR@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6978444_0	502025.Hoch_1577	3.877e-160	539.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6978444_3	1340493.JNIF01000003_gene2912	0.0007936	44.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS3_k127_6990543_4	314230.DSM3645_30116	1.575e-33	130.0	COG1233@1|root,COG1233@2|Bacteria,2IYK4@203682|Planctomycetes	203682|Planctomycetes	C	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_6990543_1	756272.Plabr_3453	5.068e-156	505.0	COG1233@1|root,COG1233@2|Bacteria,2IXJU@203682|Planctomycetes	203682|Planctomycetes	C	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_6990543_5	794903.OPIT5_30050	1.634e-27	113.0	COG0236@1|root,COG0236@2|Bacteria,46W39@74201|Verrucomicrobia,3K88G@414999|Opitutae	414999|Opitutae	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_6990543_0	583355.Caka_1850	1.641e-179	571.0	COG0304@1|root,COG0304@2|Bacteria,46V0S@74201|Verrucomicrobia,3K7MU@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_6990543_2	1123242.JH636438_gene5703	5.047e-112	371.0	COG0451@1|root,COG0451@2|Bacteria,2IX97@203682|Planctomycetes	203682|Planctomycetes	M	PFAM 3-beta hydroxysteroid dehydrogenase isomerase	-	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
CMS3_k127_6990543_3	344747.PM8797T_01759	1.71e-107	355.0	COG0318@1|root,COG0318@2|Bacteria,2IXPM@203682|Planctomycetes	203682|Planctomycetes	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
CMS3_k127_7005434_3	861299.J421_3663	2.163e-96	322.0	COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_7005434_6	1121920.AUAU01000025_gene2333	1.53e-49	190.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
CMS3_k127_7005434_8	1356852.N008_05720	8.237e-26	122.0	COG1629@1|root,COG2312@1|root,COG1629@2|Bacteria,COG2312@2|Bacteria,4NW00@976|Bacteroidetes,47SG3@768503|Cytophagia	976|Bacteroidetes	P	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarbopepD_reg_2,Erythro_esteras
CMS3_k127_7005434_1	1142394.PSMK_14680	5.499e-122	415.0	COG0168@1|root,COG0168@2|Bacteria,2IYFA@203682|Planctomycetes	203682|Planctomycetes	P	COG0168 Trk-type K transport systems, membrane components	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS3_k127_7005434_2	1142394.PSMK_23270	3.14e-105	357.0	COG0569@1|root,COG0569@2|Bacteria,2IXXC@203682|Planctomycetes	203682|Planctomycetes	C	TRK potassium uptake system protein (TrkA-2)	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS3_k127_7005434_9	314230.DSM3645_22996	3.311e-20	104.0	COG0308@1|root,COG0308@2|Bacteria,2J52K@203682|Planctomycetes	203682|Planctomycetes	E	Protein of unknown function (DUF1570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
CMS3_k127_7005434_7	1123242.JH636435_gene2389	2.389e-49	184.0	COG0062@1|root,COG0062@2|Bacteria,2IZU6@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX	nnrE	-	5.1.99.6	ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	YjeF_N
CMS3_k127_7005434_5	521674.Plim_3870	7.377e-83	295.0	COG1007@1|root,COG1007@2|Bacteria,2IXC6@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_7005434_0	237368.SCABRO_01998	9.401e-141	467.0	COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes	203682|Planctomycetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS3_k127_7005434_4	1232410.KI421424_gene1792	2.796e-91	313.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,43TW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CMS3_k127_7005882_8	483219.LILAB_17515	1.765e-05	59.0	COG0457@1|root,COG3827@1|root,COG0457@2|Bacteria,COG3827@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2YVS5@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
CMS3_k127_7005882_7	314230.DSM3645_21599	1.822e-07	61.0	COG0177@1|root,COG0177@2|Bacteria,2IZDJ@203682|Planctomycetes	203682|Planctomycetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
CMS3_k127_7005882_6	938288.HG326224_gene1564	6.111e-13	75.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS3_k127_7005882_5	696281.Desru_2804	6.565e-18	88.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia,263AU@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
CMS3_k127_7005882_0	886293.Sinac_5504	4.076e-156	526.0	COG0532@1|root,COG0532@2|Bacteria,2IXYU@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS3_k127_7005882_1	1142394.PSMK_13860	6.952e-146	476.0	COG0195@1|root,COG0195@2|Bacteria,2IWY3@203682|Planctomycetes	203682|Planctomycetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS3_k127_7005882_4	1123242.JH636436_gene464	1.986e-48	178.0	COG0698@1|root,COG0698@2|Bacteria,2IZKI@203682|Planctomycetes	203682|Planctomycetes	G	COG0698 Ribose 5-phosphate isomerase RpiB	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
CMS3_k127_7005882_3	314230.DSM3645_08617	2.005e-64	234.0	COG0009@1|root,COG0394@1|root,COG0009@2|Bacteria,COG0394@2|Bacteria,2IX5F@203682|Planctomycetes	203682|Planctomycetes	T	Belongs to the SUA5 family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc,Sua5_yciO_yrdC
CMS3_k127_7005882_2	886293.Sinac_3502	1.012e-108	361.0	COG0500@1|root,COG2226@2|Bacteria,2IXEP@203682|Planctomycetes	203682|Planctomycetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS3_k127_7008625_0	234267.Acid_5940	2.208e-70	258.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7024367_1	1192034.CAP_0615	2.936e-101	346.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2YUAI@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9
CMS3_k127_7024367_2	760568.Desku_0806	1.33e-82	285.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
CMS3_k127_7024367_4	56780.SYN_02636	4.685e-60	216.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_7024367_10	794903.OPIT5_17645	9.566e-21	95.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,3K8DW@414999|Opitutae	414999|Opitutae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS3_k127_7024367_7	1123508.JH636443_gene5099	1.098e-27	119.0	COG2172@1|root,COG2172@2|Bacteria,2J0BZ@203682|Planctomycetes	203682|Planctomycetes	T	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS3_k127_7024367_8	1142394.PSMK_14510	2.956e-24	106.0	COG1366@1|root,COG1366@2|Bacteria,2J02R@203682|Planctomycetes	203682|Planctomycetes	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS3_k127_7024367_6	1125863.JAFN01000001_gene1178	1.518e-41	165.0	28Q1P@1|root,2ZCJY@2|Bacteria,1RCE9@1224|Proteobacteria,42R28@68525|delta/epsilon subdivisions,2WN78@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
CMS3_k127_7024367_0	1047013.AQSP01000142_gene222	1.022e-231	738.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS3_k127_7024367_5	886293.Sinac_4453	2.988e-54	202.0	COG2365@1|root,COG2365@2|Bacteria,2IZQ7@203682|Planctomycetes	203682|Planctomycetes	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2,DUF442
CMS3_k127_7024367_3	1120956.JHZK01000005_gene2208	1.099e-66	254.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,1JMZ8@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	Ferrochelatase	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS3_k127_7024367_9	1158146.KB907130_gene1406	3.781e-24	108.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1WWI5@135613|Chromatiales	135613|Chromatiales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS3_k127_7039168_2	1267533.KB906734_gene4287	2.095e-12	76.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria	57723|Acidobacteria	KU	WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
CMS3_k127_7039168_0	195250.CM001776_gene1220	5.27e-75	287.0	COG2304@1|root,COG3209@1|root,COG2304@2|Bacteria,COG3209@2|Bacteria,1GJ0D@1117|Cyanobacteria,1H29D@1129|Synechococcus	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat,SdrD_B
CMS3_k127_7039168_1	768671.ThimaDRAFT_1264	4.374e-22	114.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Chlam_PMP
CMS3_k127_7045069_1	631454.N177_1317	1.617e-49	185.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6B7@28211|Alphaproteobacteria,1JP79@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
CMS3_k127_7045069_0	1137799.GZ78_01880	4.607e-94	313.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1XH6C@135619|Oceanospirillales	135619|Oceanospirillales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS3_k127_7068578_5	1121920.AUAU01000006_gene301	1.289e-06	51.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7068578_2	1108045.GORHZ_123_00250	7.04e-43	160.0	COG0346@1|root,COG0346@2|Bacteria,2GPM4@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_7068578_1	1121920.AUAU01000006_gene301	2.81e-49	183.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7068578_0	1385513.N780_03265	3.344e-174	570.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,2Y8VG@289201|Pontibacillus	91061|Bacilli	E	Oligopeptidase PepB	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS3_k127_7068578_3	349741.Amuc_1064	2.275e-22	107.0	COG3104@1|root,COG3104@2|Bacteria,46VMC@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_7069575_6	1120985.AUMI01000015_gene1538	9.508e-36	149.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4H40K@909932|Negativicutes	909932|Negativicutes	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CMS3_k127_7069575_3	909663.KI867150_gene2054	5.796e-77	267.0	COG2836@1|root,COG2836@2|Bacteria,1QVGG@1224|Proteobacteria,432GS@68525|delta/epsilon subdivisions,2WXZW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS3_k127_7069575_4	1144275.COCOR_00104	1.553e-74	257.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_7069575_2	344747.PM8797T_15151	9.257e-147	484.0	COG1520@1|root,COG1520@2|Bacteria,2IYI8@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_7069575_5	1192034.CAP_1876	1.905e-60	229.0	COG4402@1|root,COG4402@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_7069575_8	378806.STAUR_8178	4.215e-10	72.0	COG1572@1|root,COG2374@1|root,COG1572@2|Bacteria,COG2374@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Big_5,CARDB,Exo_endo_phos,LTD,Laminin_G_3
CMS3_k127_7069575_7	9978.XP_004592700.1	2.343e-16	92.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTVB@33213|Bilateria,4845F@7711|Chordata,48VXT@7742|Vertebrata,3JDTM@40674|Mammalia,35IJ6@314146|Euarchontoglires	33208|Metazoa	T	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	LRP6	GO:0000003,GO:0000902,GO:0000904,GO:0001101,GO:0001501,GO:0001654,GO:0001664,GO:0001667,GO:0001702,GO:0001745,GO:0001756,GO:0001763,GO:0001837,GO:0001838,GO:0001841,GO:0001843,GO:0001932,GO:0001933,GO:0001947,GO:0002009,GO:0002011,GO:0002053,GO:0002165,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003143,GO:0003306,GO:0003307,GO:0003308,GO:0003344,GO:0003401,GO:0003674,GO:0004857,GO:0004888,GO:0005041,GO:0005102,GO:0005109,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0005901,GO:0006355,GO:0006357,GO:0006469,GO:0006810,GO:0006869,GO:0006873,GO:0006874,GO:0006875,GO:0006897,GO:0006898,GO:0006928,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007204,GO:0007267,GO:0007268,GO:0007275,GO:0007350,GO:0007365,GO:0007367,GO:0007368,GO:0007369,GO:0007389,GO:0007399,GO:0007405,GO:0007417,GO:0007420,GO:0007423,GO:0007444,GO:0007447,GO:0007472,GO:0007476,GO:0007507,GO:0007548,GO:0007552,GO:0007560,GO:0007584,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008104,GO:0008150,GO:0008283,GO:0008284,GO:0008285,GO:0008587,GO:0009605,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009799,GO:0009826,GO:0009855,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009948,GO:0009950,GO:0009952,GO:0009953,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0009991,GO:0010001,GO:0010008,GO:0010033,GO:0010171,GO:0010243,GO:0010464,GO:0010468,GO:0010556,GO:0010557,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010646,GO:0010647,GO:0010648,GO:0010656,GO:0010660,GO:0010720,GO:0010876,GO:0010941,GO:0010942,GO:0010975,GO:0010976,GO:0012505,GO:0014020,GO:0014029,GO:0014033,GO:0014070,GO:0015026,GO:0015850,GO:0015918,GO:0016020,GO:0016043,GO:0016049,GO:0016055,GO:0016192,GO:0016202,GO:0016331,GO:0016477,GO:0017145,GO:0017147,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019534,GO:0019725,GO:0021532,GO:0021535,GO:0021536,GO:0021537,GO:0021543,GO:0021549,GO:0021575,GO:0021587,GO:0021794,GO:0021795,GO:0021861,GO:0021872,GO:0021873,GO:0021874,GO:0021885,GO:0021903,GO:0021915,GO:0021932,GO:0021943,GO:0021953,GO:0021987,GO:0022008,GO:0022029,GO:0022037,GO:0022411,GO:0022414,GO:0022603,GO:0022610,GO:0022612,GO:0022857,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030003,GO:0030111,GO:0030154,GO:0030177,GO:0030178,GO:0030182,GO:0030228,GO:0030234,GO:0030278,GO:0030301,GO:0030326,GO:0030879,GO:0030900,GO:0030901,GO:0030902,GO:0030917,GO:0031076,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031346,GO:0031399,GO:0031400,GO:0031410,GO:0031667,GO:0031901,GO:0031982,GO:0032268,GO:0032269,GO:0032365,GO:0032366,GO:0032367,GO:0032501,GO:0032502,GO:0032984,GO:0032989,GO:0032991,GO:0033036,GO:0033273,GO:0033673,GO:0033993,GO:0034103,GO:0034105,GO:0034185,GO:0034391,GO:0034392,GO:0034613,GO:0035050,GO:0035051,GO:0035107,GO:0035108,GO:0035112,GO:0035113,GO:0035114,GO:0035115,GO:0035116,GO:0035120,GO:0035136,GO:0035137,GO:0035148,GO:0035218,GO:0035220,GO:0035223,GO:0035239,GO:0035261,GO:0035282,GO:0035295,GO:0036314,GO:0036315,GO:0036342,GO:0036445,GO:0036477,GO:0038023,GO:0038024,GO:0040007,GO:0040011,GO:0042063,GO:0042074,GO:0042127,GO:0042221,GO:0042325,GO:0042326,GO:0042475,GO:0042476,GO:0042493,GO:0042592,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042981,GO:0043009,GO:0043010,GO:0043025,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043235,GO:0043549,GO:0043933,GO:0044092,GO:0044093,GO:0044297,GO:0044332,GO:0044335,GO:0044340,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044853,GO:0045121,GO:0045124,GO:0045202,GO:0045595,GO:0045596,GO:0045597,GO:0045598,GO:0045599,GO:0045664,GO:0045666,GO:0045778,GO:0045780,GO:0045787,GO:0045843,GO:0045859,GO:0045893,GO:0045935,GO:0045936,GO:0045944,GO:0045992,GO:0045995,GO:0046849,GO:0046850,GO:0046852,GO:0046907,GO:0046983,GO:0048048,GO:0048070,GO:0048073,GO:0048076,GO:0048103,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048592,GO:0048593,GO:0048596,GO:0048598,GO:0048608,GO:0048634,GO:0048635,GO:0048646,GO:0048699,GO:0048705,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048749,GO:0048754,GO:0048762,GO:0048771,GO:0048806,GO:0048856,GO:0048863,GO:0048869,GO:0048870,GO:0048878,GO:0050678,GO:0050680,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050877,GO:0050890,GO:0050896,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051301,GO:0051338,GO:0051348,GO:0051480,GO:0051593,GO:0051641,GO:0051649,GO:0051674,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0051962,GO:0055024,GO:0055026,GO:0055057,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060019,GO:0060021,GO:0060026,GO:0060039,GO:0060041,GO:0060042,GO:0060059,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060322,GO:0060323,GO:0060324,GO:0060325,GO:0060429,GO:0060438,GO:0060439,GO:0060443,GO:0060444,GO:0060485,GO:0060534,GO:0060535,GO:0060536,GO:0060541,GO:0060548,GO:0060560,GO:0060562,GO:0060592,GO:0060596,GO:0060603,GO:0060606,GO:0060788,GO:0060828,GO:0061053,GO:0061138,GO:0061180,GO:0061307,GO:0061310,GO:0061311,GO:0061316,GO:0061324,GO:0061351,GO:0061371,GO:0061448,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071542,GO:0071696,GO:0071697,GO:0071702,GO:0071840,GO:0071900,GO:0071901,GO:0071936,GO:0071944,GO:0072089,GO:0072175,GO:0072359,GO:0072503,GO:0072507,GO:0072657,GO:0072659,GO:0080090,GO:0090009,GO:0090090,GO:0090118,GO:0090175,GO:0090178,GO:0090244,GO:0090245,GO:0090254,GO:0090263,GO:0090596,GO:0097305,GO:0097306,GO:0097458,GO:0097708,GO:0098588,GO:0098589,GO:0098590,GO:0098609,GO:0098657,GO:0098771,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120035,GO:0198738,GO:1901219,GO:1901220,GO:1901698,GO:1901700,GO:1901701,GO:1901861,GO:1901862,GO:1901963,GO:1901998,GO:1902680,GO:1903506,GO:1903508,GO:1904412,GO:1904413,GO:1904886,GO:1904928,GO:1904948,GO:1904953,GO:1905114,GO:1905276,GO:1905277,GO:1905330,GO:1905331,GO:1990778,GO:1990851,GO:1990909,GO:2000026,GO:2000027,GO:2000050,GO:2000051,GO:2000053,GO:2000055,GO:2000095,GO:2000112,GO:2000136,GO:2000148,GO:2000149,GO:2000150,GO:2000151,GO:2000159,GO:2000160,GO:2000161,GO:2000162,GO:2000163,GO:2000164,GO:2000165,GO:2000166,GO:2000167,GO:2000168,GO:2000826,GO:2001141	-	ko:K03068	ko04150,ko04310,ko05200,ko05224,ko05225,ko05226,map04150,map04310,map05200,map05224,map05225,map05226	-	-	-	ko00000,ko00001,ko04131	-	-	-	FXa_inhibition,Ldl_recept_a,Ldl_recept_b
CMS3_k127_7069575_9	1050202.KB913024_gene3027	0.0001312	47.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2GIVM@201174|Actinobacteria	201174|Actinobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,KAsynt_C_assoc,Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_7069575_0	502025.Hoch_4496	3.035e-256	804.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,42Q8W@68525|delta/epsilon subdivisions,2WJVN@28221|Deltaproteobacteria,2YWG3@29|Myxococcales	28221|Deltaproteobacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_7069575_1	518766.Rmar_1421	6.87e-159	511.0	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_7094076_2	443143.GM18_1016	2.81e-28	121.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_7094076_4	247490.KSU1_C0404	2.605e-09	69.0	COG1333@1|root,COG1333@2|Bacteria,2J0U6@203682|Planctomycetes	203682|Planctomycetes	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CMS3_k127_7094076_0	945713.IALB_1309	1.477e-131	434.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_7094076_1	880073.Calab_3405	1.06e-55	214.0	COG4191@1|root,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
CMS3_k127_7094076_3	400682.PAC_15707855	6.155e-16	89.0	KOG2177@1|root,KOG2177@2759|Eukaryota	400682.PAC_15707855|-	O	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7095542_11	1121346.KB899823_gene2380	3.739e-39	154.0	COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,26QRV@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter	mntC	-	-	ko:K11709,ko:K19976	ko02010,map02010	M00319,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC-3
CMS3_k127_7095542_5	935845.JADQ01000056_gene425	5.654e-82	284.0	COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli,26TQS@186822|Paenibacillaceae	91061|Bacilli	P	Manganese ABC transporter ATP-binding protein	mntB	-	3.6.3.35	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00243,M00244,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	iYO844.BSU30760	ABC_tran
CMS3_k127_7095542_6	926550.CLDAP_26720	4.185e-65	233.0	COG0803@1|root,COG0803@2|Bacteria,2G5WF@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K11707	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
CMS3_k127_7095542_7	861299.J421_4361	2.857e-58	212.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS3_k127_7095542_12	1121405.dsmv_1388	2.472e-26	113.0	2APA5@1|root,31EC7@2|Bacteria,1RHMQ@1224|Proteobacteria,42UND@68525|delta/epsilon subdivisions,2WQK4@28221|Deltaproteobacteria,2MM23@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7095542_9	1121396.KB892990_gene4470	1.361e-49	190.0	COG0697@1|root,COG0697@2|Bacteria,1Q9JX@1224|Proteobacteria,434FQ@68525|delta/epsilon subdivisions,2WYT5@28221|Deltaproteobacteria,2MN71@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_7095542_10	1142394.PSMK_29720	6.19e-46	172.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS3_k127_7095542_0	530564.Psta_4031	6.528e-182	582.0	COG0015@1|root,COG0015@2|Bacteria,2IXU4@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS3_k127_7095542_2	314230.DSM3645_05120	4.908e-99	334.0	COG1186@1|root,COG1186@2|Bacteria,2IWU3@203682|Planctomycetes	203682|Planctomycetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_7095542_4	595460.RRSWK_03120	7.35e-89	321.0	COG0515@1|root,COG0515@2|Bacteria,2IYAA@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7095542_15	575540.Isop_1814	3.108e-18	99.0	COG1716@1|root,COG1716@2|Bacteria,2IZA4@203682|Planctomycetes	203682|Planctomycetes	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_7095542_17	575540.Isop_1769	8.904e-13	74.0	2E607@1|root,330PM@2|Bacteria,2J0MD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7095542_18	76114.ebA3711	1.183e-06	61.0	COG4655@1|root,COG4655@2|Bacteria,1R8E5@1224|Proteobacteria,2WGSJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
CMS3_k127_7095542_13	926560.KE387023_gene1640	7.566e-26	121.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K12516	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.5.5	-	-	SdrD_B
CMS3_k127_7095542_3	1038859.AXAU01000002_gene344	1.362e-97	332.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,3JRYC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	MA20_20675	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_7095542_8	1210884.HG799465_gene11336	1.492e-56	213.0	COG2974@1|root,COG2974@2|Bacteria,2IX80@203682|Planctomycetes	203682|Planctomycetes	L	May be involved in recombination	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7095542_1	296587.XP_002501332.1	2.554e-170	553.0	COG0367@1|root,KOG0571@2759|Eukaryota,37JXE@33090|Viridiplantae,34HGB@3041|Chlorophyta	3041|Chlorophyta	E	asparagine	ASN2	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_7095542_14	1356852.N008_12995	9.904e-26	116.0	COG1266@1|root,COG1266@2|Bacteria,4NPCK@976|Bacteroidetes,47VJS@768503|Cytophagia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_7111815_1	1206731.BAGB01000171_gene4648	1.099e-15	81.0	COG1695@1|root,COG1695@2|Bacteria,2I8DQ@201174|Actinobacteria,4FXRP@85025|Nocardiaceae	201174|Actinobacteria	K	Virulence activator alpha C-term	padR	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
CMS3_k127_7111815_0	234267.Acid_2013	3.529e-111	380.0	COG2936@1|root,COG2936@2|Bacteria,3Y6W3@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_7111815_2	1307761.L21SP2_3313	1.115e-08	66.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
CMS3_k127_7137494_1	1134413.ANNK01000087_gene236	3.877e-44	166.0	2A6Y1@1|root,30VSZ@2|Bacteria,1UBKQ@1239|Firmicutes,4IN0U@91061|Bacilli,1ZMG5@1386|Bacillus	91061|Bacilli	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_7137494_0	1123501.KB902297_gene3630	1.464e-164	537.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS3_k127_7137494_2	1121861.KB899918_gene3285	1.785e-27	112.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,2JRBN@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS3_k127_7164307_0	326427.Cagg_2562	9.594e-156	516.0	COG1404@1|root,COG1404@2|Bacteria,2G5S0@200795|Chloroflexi,376YT@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
CMS3_k127_7171378_0	880072.Desac_2826	7.791e-95	328.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,42U77@68525|delta/epsilon subdivisions,2WQ4R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS3_k127_7171378_2	1009370.ALO_07118	6.502e-67	252.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4H2F4@909932|Negativicutes	909932|Negativicutes	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
CMS3_k127_7171378_3	391625.PPSIR1_08142	1.915e-59	214.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YURD@29|Myxococcales	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_7171378_7	886293.Sinac_2463	1.041e-23	108.0	COG0250@1|root,COG0250@2|Bacteria,2J0E8@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
CMS3_k127_7171378_9	234267.Acid_4638	3.439e-15	89.0	COG1596@1|root,COG1596@2|Bacteria,3Y7Z0@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS3_k127_7171378_4	1033743.CAES01000096_gene2732	1.323e-41	164.0	COG1082@1|root,COG1082@2|Bacteria,1UZJZ@1239|Firmicutes	1239|Firmicutes	G	PFAM Xylose isomerase domain-containing protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_7171378_1	926569.ANT_27060	2.67e-67	240.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7171378_8	326427.Cagg_0122	2.731e-19	104.0	COG0577@1|root,COG0577@2|Bacteria,2G6IW@200795|Chloroflexi,374ZQ@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_7171378_6	1068980.ARVW01000001_gene7446	4.429e-25	114.0	COG1695@1|root,COG1695@2|Bacteria,2GNEN@201174|Actinobacteria,4EBZ6@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
CMS3_k127_7171378_5	1089545.KB913037_gene457	5.133e-28	121.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4E05J@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase, CocE NonD family	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_7219250_0	1131269.AQVV01000012_gene2615	4.386e-71	244.0	COG0623@1|root,COG0623@2|Bacteria	2|Bacteria	I	enoyl-[acyl-carrier-protein] reductase (NADH) activity	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_7219250_4	1121405.dsmv_3364	8.704e-24	114.0	COG2091@1|root,COG2091@2|Bacteria,1N7NG@1224|Proteobacteria,42WPP@68525|delta/epsilon subdivisions,2WRW2@28221|Deltaproteobacteria,2MM1E@213118|Desulfobacterales	28221|Deltaproteobacteria	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_7219250_3	760192.Halhy_6324	2.366e-28	124.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	TauE
CMS3_k127_7219250_2	502025.Hoch_6539	5.529e-29	133.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7219250_7	1234364.AMSF01000073_gene1978	0.0008796	48.0	COG1787@1|root,COG1787@2|Bacteria,1RAHG@1224|Proteobacteria,1RYIV@1236|Gammaproteobacteria,1X6AQ@135614|Xanthomonadales	135614|Xanthomonadales	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat,zf-C4_Topoisom
CMS3_k127_7219250_1	324602.Caur_0299	7.189e-66	245.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_7219250_6	324602.Caur_0300	1.22e-07	59.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7219250_5	765420.OSCT_0770	3.088e-15	90.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_7232259_7	314282.PCNPT3_11960	8.298e-19	85.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,2QHVB@267894|Psychromonadaceae	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS3_k127_7232259_1	1163617.SCD_n00622	0.0	1163.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_7232259_4	323848.Nmul_A0763	2.239e-76	258.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria,372P2@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS3_k127_7232259_5	580332.Slit_0762	5.6e-65	224.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2VR2H@28216|Betaproteobacteria,44VUV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS3_k127_7232259_2	1297865.APJD01000012_gene1380	5.787e-141	458.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,3JRQ8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	MA20_39895	-	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN
CMS3_k127_7232259_8	1380394.JADL01000002_gene1603	2.281e-06	53.0	COG1024@1|root,COG1024@2|Bacteria,1NTWU@1224|Proteobacteria,2UPY0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_7232259_6	426114.THI_2607	1.635e-55	202.0	COG1352@1|root,COG1352@2|Bacteria,1QVIR@1224|Proteobacteria,2WGT0@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_7232259_0	1163617.SCD_n00619	0.0	2312.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS3_k127_7232259_3	323848.Nmul_A0759	6.951e-135	432.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria,37253@32003|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS3_k127_7240814_1	309807.SRU_1403	3.936e-61	218.0	COG0295@1|root,COG0295@2|Bacteria,4PENS@976|Bacteroidetes,1FJCT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
CMS3_k127_7240814_0	1089550.ATTH01000001_gene2141	2.168e-91	309.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,1FJUK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_7250137_2	1500894.JQNN01000001_gene756	2.785e-05	54.0	COG4206@1|root,COG4206@2|Bacteria,1R47X@1224|Proteobacteria	1224|Proteobacteria	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS3_k127_7250137_0	1044.EH31_05300	4.87e-141	467.0	COG1858@1|root,COG1858@2|Bacteria,1QUP2@1224|Proteobacteria,2TW2M@28211|Alphaproteobacteria,2KCYB@204457|Sphingomonadales	204457|Sphingomonadales	P	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_7250137_1	1313421.JHBV01000019_gene5349	5.513e-34	134.0	COG4912@1|root,COG4912@2|Bacteria,4NJ0V@976|Bacteroidetes,1ITTR@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS3_k127_7267349_32	266117.Rxyl_1070	6.023e-07	54.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS3_k127_7267349_22	525257.HMPREF0204_11565	5.23e-45	173.0	2C312@1|root,2Z7N1@2|Bacteria,4NFNW@976|Bacteroidetes,1I541@117743|Flavobacteriia,3ZRGY@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7267349_26	234267.Acid_4736	7.675e-15	89.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_7267349_29	330214.NIDE2245	1.133e-12	81.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_4,Fer4_5,Fer4_9
CMS3_k127_7267349_31	1210884.HG799462_gene8057	3.945e-10	74.0	2B9HV@1|root,322W0@2|Bacteria,2IZR4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7267349_16	1463920.JOGB01000047_gene3032	1.029e-61	230.0	COG2931@1|root,COG3209@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	ALF,LRR_5,PT-HINT,Ricin_B_lectin,VCBS,fn3
CMS3_k127_7267349_0	1121918.ARWE01000001_gene1293	2.242e-170	544.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43SDW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Serine hydroxymethyltransferase	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_7267349_2	867903.ThesuDRAFT_02282	9.412e-107	359.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_7267349_17	1142394.PSMK_07270	3.016e-60	231.0	COG1173@1|root,COG1173@2|Bacteria,2IYF0@203682|Planctomycetes	203682|Planctomycetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS3_k127_7267349_8	1192034.CAP_8072	7.042e-75	265.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2X5XK@28221|Deltaproteobacteria,2Z2YK@29|Myxococcales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	appB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS3_k127_7267349_6	1396418.BATQ01000027_gene5238	3.157e-76	280.0	COG4166@1|root,COG4166@2|Bacteria,46SBG@74201|Verrucomicrobia,2ITVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
CMS3_k127_7267349_18	886293.Sinac_3725	3.875e-60	214.0	COG2344@1|root,COG2344@2|Bacteria,2IZG6@203682|Planctomycetes	203682|Planctomycetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
CMS3_k127_7267349_24	926692.AZYG01000018_gene327	4.608e-21	98.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia,3WAXG@53433|Halanaerobiales	186801|Clostridia	O	PFAM NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
CMS3_k127_7267349_7	269799.Gmet_2052	7.049e-76	267.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,43U4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS3_k127_7267349_11	1396141.BATP01000003_gene4868	1.313e-72	256.0	COG1131@1|root,COG1131@2|Bacteria,46SHV@74201|Verrucomicrobia,2IVHQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_7267349_23	1396141.BATP01000003_gene4869	1.748e-27	123.0	COG1277@1|root,COG1277@2|Bacteria,46XHK@74201|Verrucomicrobia,2IVXU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7267349_33	768066.HELO_4041	0.0002404	51.0	2CGY3@1|root,332WC@2|Bacteria,1RENQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7267349_19	886293.Sinac_3181	4.162e-54	205.0	COG0438@1|root,COG0438@2|Bacteria,2IZ0H@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7267349_25	1111454.HMPREF1250_1699	5.695e-16	84.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4H4A5@909932|Negativicutes	909932|Negativicutes	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS3_k127_7267349_10	1123508.JH636443_gene4981	8.717e-73	256.0	COG0275@1|root,COG0275@2|Bacteria,2IXPV@203682|Planctomycetes	203682|Planctomycetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS3_k127_7267349_28	1142394.PSMK_21480	8.266e-13	80.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_7267349_4	644282.Deba_2787	5.461e-100	349.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
CMS3_k127_7267349_1	644966.Tmar_0865	1.575e-120	405.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_7267349_12	96561.Dole_2791	5.872e-71	258.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2MIES@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_7267349_5	596153.Alide_3709	7.609e-87	300.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,4ABVH@80864|Comamonadaceae	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS3_k127_7267349_15	1236976.JCM16418_1077	2.758e-64	235.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,26S7H@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the SEDS family	spoVE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS3_k127_7267349_20	290318.Cvib_1753	2.516e-52	209.0	COG0707@1|root,COG0707@2|Bacteria,1FDRW@1090|Chlorobi	1090|Chlorobi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS3_k127_7267349_3	273068.TTE2575	3.753e-104	355.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,42ERF@68295|Thermoanaerobacterales	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_7267349_13	886293.Sinac_6149	2.601e-68	242.0	COG0812@1|root,COG0812@2|Bacteria,2IYGQ@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS3_k127_7267349_14	1123242.JH636436_gene468	2.971e-67	242.0	COG1181@1|root,COG1181@2|Bacteria,2IZHT@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_7267349_27	1142394.PSMK_01180	1.648e-14	85.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS3_k127_7267349_34	1184607.AUCHE_08_02400	0.0007598	50.0	COG1082@1|root,COG1082@2|Bacteria,2GJKJ@201174|Actinobacteria,4F75X@85018|Dermatophilaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_7267349_9	1293054.HSACCH_00487	4.359e-74	258.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WB8I@53433|Halanaerobiales	186801|Clostridia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CMS3_k127_7267349_30	886293.Sinac_5260	3.843e-10	64.0	COG0828@1|root,COG0828@2|Bacteria,2J1A6@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS3_k127_7267349_21	935565.JAEM01000001_gene515	6.874e-51	183.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2PUA7@265|Paracoccus	28211|Alphaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS3_k127_7271163_4	391623.TERMP_01389	5.511e-05	53.0	arCOG07402@1|root,arCOG07402@2157|Archaea,2Y300@28890|Euryarchaeota,242KQ@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7271163_3	102232.GLO73106DRAFT_00020540	3.675e-21	106.0	2EGZK@1|root,33ARQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7271163_0	273116.14324601	3.402e-70	251.0	COG0464@1|root,arCOG01307@2157|Archaea,2Y840@28890|Euryarchaeota,242IC@183967|Thermoplasmata	183967|Thermoplasmata	D	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS3_k127_7271163_2	439235.Dalk_0759	1.465e-51	194.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria,2MIYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_7271163_5	439235.Dalk_3523	0.0008195	42.0	COG0614@1|root,COG0614@2|Bacteria,1Q4BV@1224|Proteobacteria,42TPS@68525|delta/epsilon subdivisions,2WQYM@28221|Deltaproteobacteria,2MNA4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_7271163_1	869210.Marky_1998	2.241e-54	200.0	COG1120@1|root,COG1120@2|Bacteria,1WIGE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	HP	ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	fecE	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS3_k127_729548_2	502025.Hoch_6539	6.967e-08	65.0	COG3055@1|root,COG3055@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_729548_0	118173.KB235914_gene2745	6.073e-10	68.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
CMS3_k127_7295693_0	1121904.ARBP01000007_gene3098	1.413e-101	353.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Sodium alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS3_k127_7295693_1	756272.Plabr_2024	3.454e-62	220.0	COG0299@1|root,COG0299@2|Bacteria,2IZ96@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS3_k127_7295693_2	314287.GB2207_06578	4.807e-43	175.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,1SZZ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	multidrug resistance protein NorM	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_7295693_3	880073.Calab_1440	1.554e-41	157.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	mpaA	GO:0000270,GO:0003674,GO:0003824,GO:0004040,GO:0004180,GO:0004181,GO:0005488,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009050,GO:0009056,GO:0009057,GO:0009253,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030203,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0046872,GO:0046914,GO:0061473,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K14054	-	-	-	-	ko00000	-	-	iEC55989_1330.EC55989_1490,iECO103_1326.ECO103_1491	Peptidase_M14
CMS3_k127_7309647_0	530564.Psta_4082	2.2e-38	160.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,SdrD_B
CMS3_k127_7311653_2	1123508.JH636444_gene5270	3.068e-12	68.0	COG2195@1|root,COG2195@2|Bacteria,2IXQY@203682|Planctomycetes	203682|Planctomycetes	E	Cleaves the N-terminal amino acid of tripeptides	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
CMS3_k127_7311653_3	1128421.JAGA01000002_gene890	6.283e-11	77.0	COG0457@1|root,COG0457@2|Bacteria,2NRQU@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7311653_0	861299.J421_0141	1.414e-54	211.0	COG2148@1|root,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_7311653_1	272560.BPSS1830	5.46e-35	155.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2VN0C@28216|Betaproteobacteria,1JZZE@119060|Burkholderiaceae	28216|Betaproteobacteria	D	PFAM lipopolysaccharide biosynthesis	epsG	-	2.7.10.1	ko:K08252,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CBP_BcsQ,CbiA,GNVR,ParA,Wzz
CMS3_k127_7311653_4	575540.Isop_3043	0.0001756	51.0	2A5JP@1|root,30UA0@2|Bacteria,2J2V0@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
CMS3_k127_731622_0	671143.DAMO_1998	2.868e-53	203.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367,DUF5122
CMS3_k127_731622_1	946077.W5A_10934	0.0009742	51.0	COG3291@1|root,COG3291@2|Bacteria,4NMA6@976|Bacteroidetes,1IJ6Q@117743|Flavobacteriia	976|Bacteroidetes	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
CMS3_k127_733968_8	533240.CRC_01930	1.244e-06	62.0	COG2304@1|root,COG2304@2|Bacteria,1G1TC@1117|Cyanobacteria,1HK3T@1161|Nostocales	1117|Cyanobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_733968_3	404589.Anae109_2631	7.179e-66	239.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,42MJF@68525|delta/epsilon subdivisions,2WUTT@28221|Deltaproteobacteria,2YXX6@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_733968_5	314345.SPV1_00245	3.614e-44	173.0	COG1215@1|root,COG1215@2|Bacteria,1QVAX@1224|Proteobacteria	1224|Proteobacteria	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_733968_7	103733.JNYO01000001_gene284	1.967e-25	119.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4E1U2@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_733968_2	1353276.JADR01000007_gene1334	1.392e-83	291.0	COG0189@1|root,COG0189@2|Bacteria,4NHYZ@976|Bacteroidetes,1I5CF@117743|Flavobacteriia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
CMS3_k127_733968_6	391625.PPSIR1_29785	2.74e-28	130.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_733968_4	1144275.COCOR_07753	5.147e-56	203.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_733968_1	1125863.JAFN01000001_gene2317	1.245e-97	327.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
CMS3_k127_733968_9	1123508.JH636439_gene624	3.531e-06	54.0	2EAK7@1|root,334NW@2|Bacteria,2J0Q7@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS3_k127_733968_0	338966.Ppro_2835	1.003e-201	657.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43TIJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS3_k127_7341099_4	756272.Plabr_2371	2.787e-40	154.0	COG1974@1|root,COG1974@2|Bacteria,2IZCV@203682|Planctomycetes	203682|Planctomycetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS3_k127_7341099_5	1142394.PSMK_28130	2.377e-39	163.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7341099_0	1210884.HG799465_gene11888	7.191e-76	270.0	COG0402@1|root,COG0402@2|Bacteria,2IYVP@203682|Planctomycetes	203682|Planctomycetes	F	COG0402 Cytosine deaminase and related metal-dependent	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_7341099_6	1298865.H978DRAFT_0923	3.765e-27	116.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,1SCNB@1236|Gammaproteobacteria,468G6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	small membrane protein	ygdD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF423
CMS3_k127_7341099_7	1278073.MYSTI_06160	2.118e-24	113.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,42VMT@68525|delta/epsilon subdivisions,2WPFB@28221|Deltaproteobacteria,2YVIK@29|Myxococcales	28221|Deltaproteobacteria	S	FxsA cytoplasmic membrane protein	fsxA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
CMS3_k127_7341099_1	886293.Sinac_5463	8.392e-64	239.0	COG3307@1|root,COG3307@2|Bacteria,2J1AC@203682|Planctomycetes	203682|Planctomycetes	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_7341099_3	1304275.C41B8_07442	1.942e-47	187.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_7341099_8	395961.Cyan7425_4938	1.066e-06	62.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1G0TN@1117|Cyanobacteria,3KJG9@43988|Cyanothece	1117|Cyanobacteria	D	PFAM lipopolysaccharide biosynthesis protein	epsB	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
CMS3_k127_7341099_2	1123508.JH636439_gene1315	6.547e-62	225.0	COG4191@1|root,COG4191@2|Bacteria,2J2PC@203682|Planctomycetes	203682|Planctomycetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_7348613_4	1122179.KB890418_gene3776	1.164e-40	158.0	COG1108@1|root,COG1108@2|Bacteria,4NH3D@976|Bacteroidetes,1IXC3@117747|Sphingobacteriia	976|Bacteroidetes	P	ABC 3 transport family	mntD	-	-	ko:K11708,ko:K11709	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
CMS3_k127_7348613_6	1131269.AQVV01000113_gene241	3.334e-17	89.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS3_k127_7348613_2	1123276.KB893246_gene637	1.207e-46	185.0	COG5504@1|root,COG5504@2|Bacteria,4NJ10@976|Bacteroidetes,47QY0@768503|Cytophagia	976|Bacteroidetes	O	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_20,DUF2268
CMS3_k127_7348613_0	1089550.ATTH01000001_gene1831	2.559e-171	573.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
CMS3_k127_7348613_3	234267.Acid_1367	1.587e-41	160.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
CMS3_k127_7348613_7	1380394.JADL01000009_gene3333	4.063e-09	69.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2U5ZN@28211|Alphaproteobacteria,2JYWM@204441|Rhodospirillales	204441|Rhodospirillales	M	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CMS3_k127_7348613_5	502025.Hoch_0984	4.268e-27	130.0	COG1506@1|root,COG1506@2|Bacteria,1R0DH@1224|Proteobacteria,43CWV@68525|delta/epsilon subdivisions,2X84T@28221|Deltaproteobacteria,2Z3KY@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PPC
CMS3_k127_7370994_0	1004785.AMBLS11_00935	8.527e-124	402.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,1RR4S@1236|Gammaproteobacteria,463ZX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_7370994_2	1209072.ALBT01000064_gene1175	6.936e-87	305.0	COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,1RSKQ@1236|Gammaproteobacteria,1FFZV@10|Cellvibrio	1236|Gammaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.15	ko:K13874	ko00053,ko01100,map00053,map01100	-	R02526	RC00537	ko00000,ko00001,ko01000	-	-	-	SGL
CMS3_k127_7370994_1	455436.DS989811_gene1613	5.657e-102	345.0	COG2273@1|root,COG4257@1|root,COG5498@1|root,COG2273@2|Bacteria,COG4257@2|Bacteria,COG5498@2|Bacteria,1R4DU@1224|Proteobacteria,1RR8D@1236|Gammaproteobacteria,464IN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl hydrolase family 81	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF5011,Glyco_hydro_81
CMS3_k127_7373925_7	278957.ABEA03000120_gene1163	2.444e-06	58.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_7373925_1	404589.Anae109_3017	2.963e-58	228.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2YZH3@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
CMS3_k127_7373925_2	1382306.JNIM01000001_gene732	7.617e-54	198.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_7373925_5	1303518.CCALI_01087	5.697e-09	61.0	COG0526@1|root,COG2834@1|root,COG0526@2|Bacteria,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_7373925_6	1198114.AciX9_1112	3.47e-08	58.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia	204432|Acidobacteriia	CO	Glutathione peroxidase	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
CMS3_k127_7373925_3	483219.LILAB_16755	2.969e-52	198.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS3_k127_7373925_0	1280390.CBQR020000137_gene3364	2.869e-58	211.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,26TNF@186822|Paenibacillaceae	91061|Bacilli	C	NAD(P)H-dependent oxidoreductase	nfrA	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CMS3_k127_7373925_4	521674.Plim_3642	7.303e-41	158.0	COG1943@1|root,COG1943@2|Bacteria,2J16A@203682|Planctomycetes	203682|Planctomycetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_7388953_10	886293.Sinac_3274	3.958e-21	95.0	COG3682@1|root,COG3682@2|Bacteria,2J0D9@203682|Planctomycetes	203682|Planctomycetes	K	penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_7388953_13	1396418.BATQ01000113_gene4691	4.194e-17	94.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_7388953_3	1382359.JIAL01000001_gene2765	1.895e-40	153.0	COG3411@1|root,COG3411@2|Bacteria,3Y54Q@57723|Acidobacteria,2JJSF@204432|Acidobacteriia	204432|Acidobacteriia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7388953_15	82654.Pse7367_2276	6.975e-16	91.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1H889@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_7388953_18	1173023.KE650771_gene5033	2.58e-06	60.0	COG0457@1|root,COG0457@2|Bacteria	1173023.KE650771_gene5033|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7388953_17	1122236.KB905141_gene1202	1.276e-08	67.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VHVG@28216|Betaproteobacteria,2KMN6@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_8
CMS3_k127_7388953_19	595460.RRSWK_02225	8.869e-06	58.0	COG2244@1|root,COG2244@2|Bacteria,2J2X5@203682|Planctomycetes	203682|Planctomycetes	S	COG2244 Membrane protein involved in the export of O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_7388953_2	1142394.PSMK_05000	2.343e-100	349.0	COG0318@1|root,COG0318@2|Bacteria,2IZ5X@203682|Planctomycetes	203682|Planctomycetes	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_7388953_5	1142394.PSMK_13590	6.425e-35	138.0	COG1762@1|root,COG1762@2|Bacteria,2IZ73@203682|Planctomycetes	203682|Planctomycetes	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
CMS3_k127_7388953_16	886293.Sinac_6477	3.693e-10	70.0	COG2165@1|root,COG2165@2|Bacteria,2IZ51@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_7388953_14	1144275.COCOR_00091	8.887e-17	96.0	COG1572@1|root,COG1572@2|Bacteria,1N4MI@1224|Proteobacteria,42USE@68525|delta/epsilon subdivisions,2WQX2@28221|Deltaproteobacteria,2YVY2@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CMS3_k127_7388953_0	1142394.PSMK_24340	7.772e-122	404.0	COG0515@1|root,COG0515@2|Bacteria,2IYFB@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7388953_8	563192.HMPREF0179_00693	3.013e-28	129.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,2M8QB@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS3_k127_7388953_4	1203606.HMPREF1526_01989	2.797e-36	148.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,36E0D@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS3_k127_7388953_1	161156.JQKW01000011_gene1027	4.042e-114	379.0	COG0536@1|root,COG0536@2|Bacteria,2GHPW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS3_k127_7388953_9	1123508.JH636445_gene6870	9.126e-26	108.0	COG0211@1|root,COG0211@2|Bacteria,2J04T@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS3_k127_7388953_7	867903.ThesuDRAFT_00021	2.516e-29	124.0	COG5496@1|root,COG5496@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_7388953_6	644966.Tmar_2152	1.848e-33	131.0	COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes	1239|Firmicutes	S	Ethyl tert-butyl ether degradation	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
CMS3_k127_7388953_12	595460.RRSWK_02048	4.696e-18	85.0	COG0398@1|root,COG0398@2|Bacteria,2J2ZN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547,SNARE_assoc
CMS3_k127_7397272_2	177437.HRM2_29440	1.105e-06	51.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,42M7C@68525|delta/epsilon subdivisions,2WKRD@28221|Deltaproteobacteria,2MKAR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS3_k127_7397272_0	1210884.HG799464_gene10774	6.459e-297	960.0	COG1228@1|root,COG1228@2|Bacteria,2IYFS@203682|Planctomycetes	203682|Planctomycetes	Q	COG1228 Imidazolonepropionase and related	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_7397272_1	886293.Sinac_3551	3.985e-26	113.0	COG2509@1|root,COG2509@2|Bacteria,2IWT5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	NAD_binding_8
CMS3_k127_7430479_0	1379698.RBG1_1C00001G1527	2.076e-102	354.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,fn3
CMS3_k127_7434139_2	234267.Acid_5749	5.474e-91	311.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_7434139_4	886293.Sinac_7220	2.436e-09	59.0	COG0642@1|root,COG2205@2|Bacteria,2IZC4@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_7434139_0	886293.Sinac_6463	2.194e-290	907.0	COG0480@1|root,COG0480@2|Bacteria,2IXUD@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_7434139_1	1121920.AUAU01000018_gene1791	1.533e-128	430.0	COG0457@1|root,COG0457@2|Bacteria,3Y3D1@57723|Acidobacteria	57723|Acidobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7434139_3	234267.Acid_4393	1.781e-53	211.0	COG0515@1|root,COG0515@2|Bacteria	234267.Acid_4393|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_743732_2	96561.Dole_2411	1.268e-42	175.0	COG1807@1|root,COG1807@2|Bacteria,1RK4G@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_743732_0	1047013.AQSP01000104_gene1410	5.347e-174	557.0	COG1236@1|root,COG1236@2|Bacteria,2NNVC@2323|unclassified Bacteria	2|Bacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CMS3_k127_743732_1	525904.Tter_0375	9.38e-102	343.0	COG0788@1|root,COG0788@2|Bacteria,2NQAH@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008864,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009256,GO:0009257,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.72,3.5.1.10	ko:K00974,ko:K01433	ko00630,ko00670,ko03013,map00630,map00670,map03013	-	R00944,R09382,R09383,R09384,R09386	RC00026,RC00078,RC00111	ko00000,ko00001,ko01000,ko03016	-	-	iSDY_1059.SDY_1284	ACT,Formyl_trans_N
CMS3_k127_744985_0	314278.NB231_11764	5.169e-197	629.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1P31Y@1224|Proteobacteria,1RQNS@1236|Gammaproteobacteria,1WZWH@135613|Chromatiales	135613|Chromatiales	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_744985_1	693977.Deipr_1035	1.55e-56	214.0	COG2268@1|root,COG2268@2|Bacteria	2|Bacteria	T	Band 7 protein	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
CMS3_k127_7493161_2	1499683.CCFF01000013_gene325	5.012e-143	477.0	COG2511@1|root,COG2511@2|Bacteria,1UPG0@1239|Firmicutes,25HFT@186801|Clostridia	186801|Clostridia	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
CMS3_k127_7493161_1	1499683.CCFF01000013_gene324	1.205e-211	668.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS3_k127_7493161_4	880072.Desac_0069	3.041e-48	197.0	COG2864@1|root,COG2864@2|Bacteria,1N5K7@1224|Proteobacteria,42U9M@68525|delta/epsilon subdivisions,2WQ6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_7493161_0	1237149.C900_05704	0.0	1059.0	COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,47JEM@768503|Cytophagia	976|Bacteroidetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_7493161_5	1254432.SCE1572_21465	4.937e-36	150.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42VXX@68525|delta/epsilon subdivisions,2X6CT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS3_k127_7493161_3	118168.MC7420_5234	1.634e-74	269.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7497669_2	1121887.AUDK01000038_gene914	1.071e-38	151.0	2C5XY@1|root,33JWG@2|Bacteria,4P82Y@976|Bacteroidetes,1IC0P@117743|Flavobacteriia,2NYDZ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7497669_1	1403819.BATR01000164_gene5537	1.015e-47	173.0	COG1397@1|root,COG1397@2|Bacteria,46VZX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7497669_0	877455.Metbo_0126	5.683e-67	241.0	COG0010@1|root,arCOG01700@2157|Archaea,2XTEP@28890|Euryarchaeota,23NYZ@183925|Methanobacteria	28890|Euryarchaeota	E	Belongs to the arginase family	speB	GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_7527578_0	1267535.KB906767_gene3277	3.997e-146	487.0	COG4122@1|root,COG4122@2|Bacteria,3Y33U@57723|Acidobacteria	57723|Acidobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7556865_3	882083.SacmaDRAFT_5454	1.386e-24	106.0	2C4D4@1|root,33ZFK@2|Bacteria,2IKPR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
CMS3_k127_7556865_2	1120934.KB894427_gene1082	4.51e-37	144.0	2C4MW@1|root,32RKK@2|Bacteria,2IQ6A@201174|Actinobacteria,4E61V@85010|Pseudonocardiales	201174|Actinobacteria	S	Lsr2	lsr2	-	-	-	-	-	-	-	-	-	-	-	Lsr2
CMS3_k127_7556865_1	1463887.KL589965_gene6164	8.747e-41	154.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
CMS3_k127_7556865_0	710111.FraQA3DRAFT_0487	3.707e-125	411.0	COG2801@1|root,COG2801@2|Bacteria,2GNRT@201174|Actinobacteria,4EUFJ@85013|Frankiales	201174|Actinobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
CMS3_k127_7556865_4	749927.AMED_5522	6.653e-24	108.0	COG3209@1|root,COG5529@1|root,COG3209@2|Bacteria,COG5529@2|Bacteria,2GK1D@201174|Actinobacteria,4DXXT@85010|Pseudonocardiales	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,SpvB,Tox-ART-HYD1
CMS3_k127_7581203_9	243231.GSU3225	8.071e-59	219.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,43AJ0@68525|delta/epsilon subdivisions,2X5Z8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7581203_2	880073.Calab_1263	7.421e-161	526.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_7581203_11	595460.RRSWK_04590	7.091e-37	147.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_7581203_16	595460.RRSWK_04589	9.764e-28	117.0	COG0071@1|root,COG0071@2|Bacteria,2J0K5@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS3_k127_7581203_15	247490.KSU1_B0183	1.764e-30	126.0	COG0071@1|root,COG0071@2|Bacteria,2J11X@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS3_k127_7581203_4	247490.KSU1_B0631	4.528e-134	443.0	COG0265@1|root,COG0265@2|Bacteria,2IY5I@203682|Planctomycetes	203682|Planctomycetes	O	PDZ domain (Also known as DHR	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_7581203_5	404589.Anae109_2747	1.415e-104	362.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WPT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS3_k127_7581203_20	290397.Adeh_2194	4.435e-18	99.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WPT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS3_k127_7581203_21	404589.Anae109_2747	4.734e-15	89.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WPT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS3_k127_7581203_17	1521187.JPIM01000094_gene1035	4.279e-26	112.0	COG0838@1|root,COG0838@2|Bacteria,2G78Y@200795|Chloroflexi,375UC@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS3_k127_7581203_7	1142394.PSMK_19510	3.113e-75	257.0	COG0377@1|root,COG0377@2|Bacteria,2IZ30@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS3_k127_7581203_10	1123242.JH636436_gene485	7.487e-46	171.0	COG0852@1|root,COG0852@2|Bacteria,2IZSU@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS3_k127_7581203_1	1142394.PSMK_16630	1.213e-163	524.0	COG0649@1|root,COG0649@2|Bacteria,2IY7J@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS3_k127_7581203_13	1123242.JH636436_gene483	5.046e-34	139.0	COG1905@1|root,COG1905@2|Bacteria,2IZEQ@203682|Planctomycetes	203682|Planctomycetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS3_k127_7581203_18	378806.STAUR_1088	1.249e-22	111.0	COG1807@1|root,COG1807@2|Bacteria,1R77I@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7581203_0	886293.Sinac_2283	7.603e-172	549.0	COG1894@1|root,COG1894@2|Bacteria,2IXJ8@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_7581203_3	521674.Plim_3863	2.13e-148	487.0	COG1034@1|root,COG1034@2|Bacteria,2IY04@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2,Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
CMS3_k127_7581203_6	1123058.KB894240_gene2004	1.781e-99	338.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1HY4Q@117743|Flavobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS3_k127_7581203_8	530564.Psta_0735	5.033e-65	227.0	COG1143@1|root,COG1143@2|Bacteria,2IZAI@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS3_k127_7581203_19	1142394.PSMK_15530	1.651e-21	104.0	COG0839@1|root,COG0839@2|Bacteria,2J0MC@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS3_k127_7581203_14	1142394.PSMK_15520	1.178e-30	128.0	COG0713@1|root,COG0713@2|Bacteria,2J0GU@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS3_k127_7581203_12	479434.Sthe_0299	3.521e-34	138.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi,27XR2@189775|Thermomicrobia	189775|Thermomicrobia	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS3_k127_767036_0	1121930.AQXG01000005_gene577	9.825e-145	473.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,1IRBZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CMS3_k127_767036_1	404589.Anae109_0565	1.463e-91	311.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_767036_4	1122176.KB903577_gene4851	2.357e-17	98.0	COG1361@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,4NDZC@976|Bacteroidetes	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CMS3_k127_767036_3	76114.ebA7211	3.943e-46	192.0	COG4932@1|root,COG4932@2|Bacteria,1PWBK@1224|Proteobacteria,2WBWH@28216|Betaproteobacteria,2KZ3K@206389|Rhodocyclales	206389|Rhodocyclales	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_767036_5	344747.PM8797T_23339	4.959e-08	61.0	COG5465@1|root,COG5465@2|Bacteria,2J0NH@203682|Planctomycetes	203682|Planctomycetes	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
CMS3_k127_767036_2	760568.Desku_2340	2.259e-52	196.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1V0RW@1239|Firmicutes,24AYH@186801|Clostridia,263KV@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_773777_1	1235797.C816_00710	7.593e-21	96.0	COG2827@1|root,COG3467@1|root,COG2827@2|Bacteria,COG3467@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,2N7U3@216572|Oscillospiraceae	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS3_k127_773777_2	1116369.KB890024_gene3250	3.139e-16	84.0	COG4274@1|root,COG4274@2|Bacteria,1RHJ3@1224|Proteobacteria,2U9XS@28211|Alphaproteobacteria,43PYA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
CMS3_k127_773777_0	195250.CM001776_gene1111	2.811e-43	167.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_808148_0	485913.Krac_10500	3.895e-138	445.0	COG0553@1|root,COG0553@2|Bacteria,2G5JY@200795|Chloroflexi	200795|Chloroflexi	L	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
CMS3_k127_80912_13	1121875.KB907559_gene534	3.008e-46	180.0	COG0657@1|root,COG0657@2|Bacteria,4NZNT@976|Bacteroidetes	976|Bacteroidetes	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_80912_6	1379698.RBG1_1C00001G0607	6.937e-116	405.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
CMS3_k127_80912_26	234267.Acid_3938	9.722e-22	98.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_80912_1	1123277.KB893218_gene6176	1.877e-249	784.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,47JKV@768503|Cytophagia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_80912_15	324602.Caur_0299	9.498e-42	177.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_80912_19	195250.CM001776_gene2903	9.482e-38	164.0	COG0729@1|root,COG0729@2|Bacteria,1GDRV@1117|Cyanobacteria	1117|Cyanobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_80912_11	1227500.C494_13791	2.502e-60	217.0	COG0500@1|root,arCOG01783@2157|Archaea,2XWBW@28890|Euryarchaeota,23UCS@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_80912_21	1210884.HG799463_gene10186	5.07e-36	151.0	COG0526@1|root,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_80912_25	886293.Sinac_7445	2.184e-22	100.0	COG0526@1|root,COG0526@2|Bacteria,2J147@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_80912_18	886293.Sinac_3874	4.684e-38	155.0	COG0526@1|root,COG4796@1|root,COG0526@2|Bacteria,COG4796@2|Bacteria,2J147@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_80912_7	861299.J421_5949	6.554e-113	398.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_5949|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_80912_2	234267.Acid_5856	6.285e-172	571.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_80912_30	1267005.KB911255_gene3062	0.0006288	52.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Big_1,CHU_C,Peptidase_S74,SLH
CMS3_k127_80912_29	204669.Acid345_4118	9.685e-08	55.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_80912_10	857087.Metme_2233	1.595e-70	259.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria,1XGE2@135618|Methylococcales	135618|Methylococcales	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_80912_23	530564.Psta_0808	3.399e-24	108.0	COG0517@1|root,COG0517@2|Bacteria,2J0MQ@203682|Planctomycetes	203682|Planctomycetes	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_80912_3	314230.DSM3645_04355	2.711e-156	504.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
CMS3_k127_80912_0	1123508.JH636440_gene2090	1.431e-249	784.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_80912_22	1123508.JH636440_gene2089	5.284e-28	121.0	COG2905@1|root,COG2905@2|Bacteria,2J53V@203682|Planctomycetes	203682|Planctomycetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_80912_4	886293.Sinac_7194	5.673e-143	465.0	COG0626@1|root,COG0626@2|Bacteria,2IYKV@203682|Planctomycetes	203682|Planctomycetes	E	Cys Met metabolism	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CMS3_k127_80912_14	1123508.JH636444_gene5649	9.711e-46	172.0	COG1595@1|root,COG1595@2|Bacteria,2J090@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_80912_9	237368.SCABRO_01931	8.059e-71	261.0	COG0728@1|root,COG0728@2|Bacteria,2IYP2@203682|Planctomycetes	203682|Planctomycetes	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS3_k127_80912_17	290397.Adeh_1534	4.845e-39	148.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria,2YVH1@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS3_k127_80912_12	357808.RoseRS_4272	7.747e-54	215.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_80912_20	1121396.KB892946_gene2917	3.06e-37	162.0	COG0823@1|root,COG3291@1|root,COG3591@1|root,COG4676@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3591@2|Bacteria,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	Germane,Gmad1
CMS3_k127_80912_8	575540.Isop_1196	4.183e-73	271.0	COG2995@1|root,COG3008@1|root,COG2995@2|Bacteria,COG3008@2|Bacteria,2J380@203682|Planctomycetes	203682|Planctomycetes	Q	MlaD protein	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
CMS3_k127_80912_16	395493.BegalDRAFT_2132	2.317e-39	155.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,1RM9Z@1236|Gammaproteobacteria,462EX@72273|Thiotrichales	72273|Thiotrichales	S	paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
CMS3_k127_80912_5	886293.Sinac_2587	1.507e-120	403.0	COG0272@1|root,COG0272@2|Bacteria,2IXIC@203682|Planctomycetes	203682|Planctomycetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS3_k127_825560_2	880073.Calab_1714	1.711e-77	266.0	COG2866@1|root,COG2866@2|Bacteria,2NQT6@2323|unclassified Bacteria	2|Bacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_825560_0	926550.CLDAP_06530	1.034e-135	444.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CMS3_k127_825560_1	31033.ENSTRUP00000017470	5.545e-81	274.0	COG0450@1|root,KOG0852@2759|Eukaryota,38B9P@33154|Opisthokonta,3B9IG@33208|Metazoa,3CS1I@33213|Bilateria,480FQ@7711|Chordata,4915Q@7742|Vertebrata,4A1J9@7898|Actinopterygii	33208|Metazoa	O	Peroxiredoxin 2	PRDX2	GO:0000122,GO:0000187,GO:0000302,GO:0000303,GO:0000305,GO:0001775,GO:0001932,GO:0001934,GO:0002237,GO:0002252,GO:0002376,GO:0002520,GO:0002532,GO:0002536,GO:0002679,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002831,GO:0002832,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0006801,GO:0006950,GO:0006952,GO:0006954,GO:0006979,GO:0007162,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008283,GO:0008340,GO:0008379,GO:0008430,GO:0009056,GO:0009266,GO:0009408,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010259,GO:0010286,GO:0010310,GO:0010468,GO:0010556,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019430,GO:0022407,GO:0022408,GO:0023051,GO:0023056,GO:0023057,GO:0030155,GO:0030193,GO:0030194,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031401,GO:0031664,GO:0031665,GO:0032088,GO:0032101,GO:0032102,GO:0032147,GO:0032268,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032943,GO:0033554,GO:0033674,GO:0033993,GO:0034599,GO:0034614,GO:0042098,GO:0042110,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042542,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043207,GO:0043209,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043433,GO:0043523,GO:0043524,GO:0043549,GO:0043900,GO:0043901,GO:0044092,GO:0044093,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0045580,GO:0045581,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0045730,GO:0045859,GO:0045860,GO:0045892,GO:0045934,GO:0045937,GO:0046649,GO:0046651,GO:0046677,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048538,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0048872,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050878,GO:0050896,GO:0051090,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051186,GO:0051187,GO:0051193,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051338,GO:0051347,GO:0051704,GO:0051707,GO:0051716,GO:0051920,GO:0055114,GO:0060255,GO:0060548,GO:0061041,GO:0065007,GO:0065008,GO:0065009,GO:0070661,GO:0070887,GO:0071450,GO:0071451,GO:0071900,GO:0071902,GO:0072593,GO:0080090,GO:0080134,GO:0090303,GO:0097237,GO:0098754,GO:0098869,GO:1900046,GO:1900048,GO:1901099,GO:1901214,GO:1901215,GO:1901700,GO:1901701,GO:1902105,GO:1902106,GO:1902531,GO:1902533,GO:1902679,GO:1903034,GO:1903036,GO:1903037,GO:1903038,GO:1903506,GO:1903507,GO:1903706,GO:1903707,GO:1990748,GO:2000026,GO:2000112,GO:2000113,GO:2000377,GO:2000378,GO:2001141,GO:2001233,GO:2001234,GO:2001236,GO:2001237,GO:2001239,GO:2001240	1.11.1.15	ko:K03386,ko:K13279	ko04146,ko04214,map04146,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS3_k127_825560_3	1142394.PSMK_29570	7.159e-65	233.0	COG0325@1|root,COG0325@2|Bacteria,2IZ9R@203682|Planctomycetes	203682|Planctomycetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS3_k127_825560_4	1192034.CAP_1807	1.565e-33	136.0	COG1435@1|root,COG1435@2|Bacteria,1PY2K@1224|Proteobacteria,42RJI@68525|delta/epsilon subdivisions,2WNKR@28221|Deltaproteobacteria,2YV2Y@29|Myxococcales	28221|Deltaproteobacteria	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
CMS3_k127_840904_1	296591.Bpro_2382	1.102e-61	218.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_840904_0	1168065.DOK_01629	1.044e-72	251.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,1RNWZ@1236|Gammaproteobacteria,1J83F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS3_k127_847182_0	1123242.JH636434_gene4155	1.519e-184	592.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_860774_8	419610.Mext_3697	5.504e-17	82.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,1JRW2@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
CMS3_k127_860774_6	344747.PM8797T_20423	8.776e-44	173.0	COG1846@1|root,COG1846@2|Bacteria,2J0SE@203682|Planctomycetes	203682|Planctomycetes	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS3_k127_860774_4	471857.Svir_22190	5.693e-75	261.0	COG4976@1|root,COG4976@2|Bacteria,2IGUS@201174|Actinobacteria,4E3AJ@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS3_k127_860774_0	530564.Psta_2175	1.827e-178	570.0	COG0438@1|root,COG0438@2|Bacteria,2IWSF@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	2.4.1.14,2.4.1.246	ko:K00696,ko:K13058	ko00500,ko01100,map00500,map01100	-	R00766,R08947	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1,S6PP
CMS3_k127_860774_5	1123242.JH636435_gene2449	1.96e-51	195.0	COG0561@1|root,COG0561@2|Bacteria,2J04R@203682|Planctomycetes	203682|Planctomycetes	S	Sucrose-6F-phosphate phosphohydrolase	-	-	3.1.3.79	ko:K13086	-	-	R08982	RC00017	ko00000,ko01000	-	-	-	S6PP
CMS3_k127_860774_1	1250006.JHZZ01000001_gene2154	1.017e-135	448.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes,1I02Y@117743|Flavobacteriia	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
CMS3_k127_860774_2	344747.PM8797T_07197	4.787e-78	271.0	COG0524@1|root,COG0524@2|Bacteria,2IZDG@203682|Planctomycetes	203682|Planctomycetes	G	COG0524 Sugar kinases, ribokinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_860774_7	1142394.PSMK_27670	1.182e-34	138.0	COG0023@1|root,COG0023@2|Bacteria	2|Bacteria	J	translation initiation factor activity	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
CMS3_k127_860774_3	56780.SYN_00221	1.177e-76	265.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,2MQHY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Putative RNA methylase family UPF0020	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
CMS3_k127_865669_0	313603.FB2170_10676	7.51e-40	160.0	2E10Y@1|root,32WGY@2|Bacteria,4NTDG@976|Bacteroidetes,1I7VE@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_865669_1	439235.Dalk_1221	3.604e-11	76.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FctA,Gram_pos_anchor,SLH,VWA,YSIRK_signal
CMS3_k127_914471_0	1142394.PSMK_24160	8.696e-180	584.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	203682|Planctomycetes	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_914471_3	247490.KSU1_B0018	1.001e-31	132.0	COG0437@1|root,COG0437@2|Bacteria,2J376@203682|Planctomycetes	203682|Planctomycetes	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_914471_4	237368.SCABRO_03716	1.314e-30	135.0	COG0735@1|root,COG0735@2|Bacteria,2IZJY@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_914471_2	756272.Plabr_0479	8.825e-34	143.0	COG4589@1|root,COG4589@2|Bacteria,2J032@203682|Planctomycetes	203682|Planctomycetes	S	Phosphatidate cytidylyltransferase	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS3_k127_914471_1	530564.Psta_2532	6.61e-96	323.0	COG1702@1|root,COG1702@2|Bacteria,2IXBB@203682|Planctomycetes	203682|Planctomycetes	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS3_k127_92079_2	572547.Amico_0074	5.036e-40	163.0	COG0348@1|root,COG0348@2|Bacteria,3TABH@508458|Synergistetes	508458|Synergistetes	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
CMS3_k127_92079_1	1304885.AUEY01000001_gene3203	1.043e-63	225.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS3_k127_92079_4	595460.RRSWK_03130	1.64e-23	107.0	2DPAK@1|root,33193@2|Bacteria,2J4CE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_92079_5	643562.Daes_0505	5.184e-19	88.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria,2MD57@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	TIGRFAM redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
CMS3_k127_92079_0	575540.Isop_2574	1.568e-178	571.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS3_k127_92079_3	1121441.AUCX01000003_gene2963	1.313e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MC8X@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	SMART regulatory protein ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_92079_6	278957.ABEA03000174_gene3405	3.223e-05	51.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46Z61@74201|Verrucomicrobia,3K8JK@414999|Opitutae	414999|Opitutae	U	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,DUF3494,PATR
CMS3_k127_924694_0	1137799.GZ78_24435	1.857e-169	541.0	COG3464@1|root,COG3464@2|Bacteria,1MV5J@1224|Proteobacteria,1RQQA@1236|Gammaproteobacteria,1XKYJ@135619|Oceanospirillales	135619|Oceanospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
CMS3_k127_952735_0	5786.XP_003286127.1	6.391e-39	169.0	KOG1225@1|root,KOG1225@2759|Eukaryota	2759|Eukaryota	L	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_972289_0	886293.Sinac_6818	8.167e-194	620.0	COG2304@1|root,COG2304@2|Bacteria,2IYBK@203682|Planctomycetes	203682|Planctomycetes	K	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
CMS3_k127_972289_5	48698.ENSPFOP00000014859	2.894e-19	103.0	KOG1565@1|root,KOG1565@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,47ZW6@7711|Chordata,48WU6@7742|Vertebrata,4A1J3@7898|Actinopterygii	33208|Metazoa	OW	Matrix metallopeptidase 24	MMP24	GO:0000003,GO:0000139,GO:0000902,GO:0000904,GO:0001838,GO:0002009,GO:0002165,GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0003007,GO:0003008,GO:0003143,GO:0003144,GO:0003313,GO:0003314,GO:0003315,GO:0003318,GO:0003319,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006928,GO:0006929,GO:0006935,GO:0006950,GO:0007154,GO:0007155,GO:0007267,GO:0007275,GO:0007276,GO:0007292,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007419,GO:0007424,GO:0007426,GO:0007444,GO:0007503,GO:0007505,GO:0007507,GO:0007552,GO:0007560,GO:0007561,GO:0007600,GO:0008037,GO:0008038,GO:0008045,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008285,GO:0009266,GO:0009581,GO:0009582,GO:0009605,GO:0009611,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009897,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010001,GO:0010467,GO:0010646,GO:0010648,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016048,GO:0016331,GO:0016477,GO:0016485,GO:0016787,GO:0019233,GO:0019538,GO:0019827,GO:0019953,GO:0022008,GO:0022411,GO:0022414,GO:0022610,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030198,GO:0030234,GO:0030425,GO:0030728,GO:0031090,GO:0031175,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032588,GO:0032989,GO:0032990,GO:0034330,GO:0034769,GO:0035050,GO:0035148,GO:0035202,GO:0035239,GO:0035295,GO:0036477,GO:0040011,GO:0040036,GO:0040037,GO:0042060,GO:0042063,GO:0042127,GO:0042221,GO:0042330,GO:0042995,GO:0043005,GO:0043062,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044087,GO:0044093,GO:0044238,GO:0044331,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0045088,GO:0045089,GO:0045165,GO:0045168,GO:0045216,GO:0045296,GO:0046331,GO:0046528,GO:0046529,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050839,GO:0050877,GO:0050896,GO:0050906,GO:0050951,GO:0050961,GO:0050965,GO:0051128,GO:0051129,GO:0051179,GO:0051604,GO:0051606,GO:0051674,GO:0051704,GO:0060429,GO:0060541,GO:0060562,GO:0060612,GO:0060828,GO:0060973,GO:0061448,GO:0061564,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0071711,GO:0071840,GO:0071944,GO:0072091,GO:0072175,GO:0072359,GO:0080134,GO:0090090,GO:0090287,GO:0090288,GO:0097150,GO:0097156,GO:0097447,GO:0097458,GO:0097485,GO:0098552,GO:0098588,GO:0098609,GO:0098727,GO:0098742,GO:0098772,GO:0098791,GO:0106030,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140096,GO:1901201,GO:1901202,GO:1901564,GO:1903053,GO:1903054,GO:2000647	-	ko:K07995,ko:K07996,ko:K07997,ko:K08002,ko:K08003	ko05206,map05206	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3377,Hemopexin,PG_binding_1,Peptidase_M10
CMS3_k127_972289_1	1267533.KB906733_gene3472	2.101e-165	550.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_972289_3	1536770.R50345_26035	1.964e-118	394.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HCW2@91061|Bacilli,27271@186822|Paenibacillaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_972289_2	1329516.JPST01000066_gene1832	1.241e-132	433.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,27B2X@186824|Thermoactinomycetaceae	91061|Bacilli	H	Quinolinate synthetase A protein	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS3_k127_972289_4	324602.Caur_2039	9.008e-40	154.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS3_k127_972289_6	756272.Plabr_1381	8.105e-15	75.0	COG1301@1|root,COG1301@2|Bacteria,2IYUE@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
CMS3_k127_975088_3	1142394.PSMK_31500	3.099e-69	246.0	COG1639@1|root,COG1639@2|Bacteria,2J0A1@203682|Planctomycetes	203682|Planctomycetes	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS3_k127_975088_1	530564.Psta_2560	5.717e-113	387.0	COG0568@1|root,COG0568@2|Bacteria,2IY72@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03086,ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
CMS3_k127_975088_5	1123073.KB899242_gene1468	2.605e-53	207.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,1RZBM@1236|Gammaproteobacteria,1X4YD@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_975088_2	1121428.DESHY_110009___1	1.643e-92	311.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia,262XA@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
CMS3_k127_975088_0	243090.RB10554	8.808e-286	891.0	COG1053@1|root,COG1053@2|Bacteria,2IX3A@203682|Planctomycetes	203682|Planctomycetes	C	succinate dehydrogenase or fumarate reductase, flavoprotein	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_975088_4	530564.Psta_0864	4.081e-55	203.0	COG2009@1|root,COG2009@2|Bacteria,2J0GW@203682|Planctomycetes	203682|Planctomycetes	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
CMS3_k127_975088_6	530564.Psta_3983	1.511e-15	88.0	2EE5D@1|root,337ZY@2|Bacteria,2J11M@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
CMS3_k127_975088_7	344747.PM8797T_11961	1.812e-10	70.0	2F6WD@1|root,33ZCF@2|Bacteria,2J3EV@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_977539_1	1183438.GKIL_3395	3.955e-97	329.0	COG0515@1|root,COG0515@2|Bacteria,1G3GV@1117|Cyanobacteria	1183438.GKIL_3395|-	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_977539_3	1192034.CAP_3514	3.917e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_977539_5	314271.RB2654_10713	1.068e-33	150.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_977539_4	1219065.VPR01S_23_00300	2.049e-34	141.0	COG5553@1|root,COG5553@2|Bacteria,1NXEP@1224|Proteobacteria,1THKY@1236|Gammaproteobacteria,1XWMJ@135623|Vibrionales	135623|Vibrionales	C	Cysteine dioxygenase type I	-	-	1.13.11.20	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	-	R00893	RC00404	ko00000,ko00001,ko01000	-	-	-	CDO_I
CMS3_k127_977539_0	1297742.A176_00719	1.921e-152	498.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS3_k127_977539_2	391625.PPSIR1_03988	3.09e-61	226.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2YUM4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_999082_1	479434.Sthe_3117	2.008e-209	668.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_999082_0	1047013.AQSP01000130_gene1862	8.742e-257	802.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	ptpA_1	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
## 3566 queries scanned
## Total time (seconds): 259.9469916820526
## Rate: 13.72 q/s