## Tue Oct 15 15:09:24 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/CMS3_bin.6.fa -m mmseqs --itype genome -o CMS3_bin.6 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/CMS3_bin.6 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS3_k127_100134_0	765420.OSCT_2187	9.58e-28	120.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_100134_1	1353537.TP2_04105	8.06e-11	70.0	COG1051@1|root,COG1051@2|Bacteria,1N1KH@1224|Proteobacteria,2UA1K@28211|Alphaproteobacteria,2XNSH@285107|Thioclava	28211|Alphaproteobacteria	F	Belongs to the Nudix hydrolase family	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_100134_2	85643.Tmz1t_0800	5.505e-06	56.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,2KURX@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	cysB	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS3_k127_1007479_1	996637.SGM_2043	0.0001243	51.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1007479_0	1499967.BAYZ01000163_gene6584	1.093e-63	231.0	COG0457@1|root,COG0470@1|root,COG0457@2|Bacteria,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	AAA,AAA_22,TIR_2
CMS3_k127_1013651_5	357808.RoseRS_0410	0.0002675	54.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
CMS3_k127_1013651_1	309801.trd_1908	3.259e-40	170.0	2A4UB@1|root,30TFV@2|Bacteria,2GBEB@200795|Chloroflexi,27Z4G@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1013651_2	1382356.JQMP01000003_gene1457	1.222e-39	169.0	2A4UB@1|root,30TFV@2|Bacteria,2GBEB@200795|Chloroflexi,27Z4G@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1013651_0	243365.CV_3201	1.314e-57	208.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2VPWT@28216|Betaproteobacteria,2KS1M@206351|Neisseriales	206351|Neisseriales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1013651_3	1121904.ARBP01000009_gene4206	1.386e-38	165.0	COG0823@1|root,COG4733@1|root,COG0823@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	DUF5050,Laminin_G_3,PD40,SLH,VCBS,zinc_ribbon_2
CMS3_k127_1013651_4	1541065.JRFE01000025_gene1986	2.626e-37	142.0	COG1487@1|root,COG1487@2|Bacteria,1G6X0@1117|Cyanobacteria,3VNGY@52604|Pleurocapsales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
CMS3_k127_1019943_3	926560.KE387023_gene1204	1.64e-59	214.0	COG2378@1|root,COG2378@2|Bacteria,1WKYM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
CMS3_k127_1019943_6	1304865.JAGF01000001_gene242	1.387e-09	65.0	COG0346@1|root,COG0346@2|Bacteria,2IN2X@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_1019943_5	1123024.AUII01000002_gene958	2.321e-18	94.0	COG0406@1|root,COG0406@2|Bacteria,2GP71@201174|Actinobacteria,4E3GB@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	pgmB	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_1019943_4	1448139.AI20_14240	1.11e-55	206.0	COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria,1SU5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS3_k127_1019943_0	112098.XP_008604901.1	2.179e-152	489.0	COG1088@1|root,KOG0747@2759|Eukaryota	2759|Eukaryota	M	dTDP-glucose 4,6-dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase_2,GDP_Man_Dehyd,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_1019943_1	1089550.ATTH01000001_gene2443	1.619e-63	225.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the citrate synthase family	prpC	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_1023149_0	1313421.JHBV01000041_gene3505	1.288e-119	404.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia	976|Bacteroidetes	S	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
CMS3_k127_1029785_1	926569.ANT_10890	3.801e-47	175.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_1029785_0	1382306.JNIM01000001_gene873	1.477e-109	368.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_1043050_1	1218075.BAYA01000005_gene2028	2.247e-102	338.0	COG0439@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2VJRB@28216|Betaproteobacteria,1K5FF@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
CMS3_k127_1043050_2	526227.Mesil_0723	2.12e-77	272.0	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,1WJYD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_1043050_4	690850.Desaf_0275	5.672e-58	207.0	COG0225@1|root,COG0225@2|Bacteria,1N2DQ@1224|Proteobacteria,42UC3@68525|delta/epsilon subdivisions,2WQBZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS3_k127_1043050_3	1828.JOKB01000019_gene1474	3.758e-70	246.0	COG0596@1|root,COG0596@2|Bacteria,2I9SQ@201174|Actinobacteria,4G1IC@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_1043050_0	42256.RradSPS_0358	1.418e-275	876.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_104309_3	324602.Caur_1238	2.014e-71	262.0	COG2823@1|root,COG5297@1|root,COG2823@2|Bacteria,COG5297@2|Bacteria,2GA85@200795|Chloroflexi,376AG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_104309_7	485913.Krac_4178	2.034e-34	138.0	2DE8Y@1|root,2ZM0Q@2|Bacteria	2|Bacteria	S	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_104309_5	1121861.KB899920_gene2919	5.874e-52	198.0	COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria,2U18B@28211|Alphaproteobacteria,2JUTA@204441|Rhodospirillales	204441|Rhodospirillales	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_104309_6	1283299.AUKG01000001_gene3267	1.314e-36	144.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,4CTFY@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_AsnC-type
CMS3_k127_104309_0	309801.trd_0523	9.261e-127	418.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,27XG2@189775|Thermomicrobia	189775|Thermomicrobia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS3_k127_104309_2	479434.Sthe_1277	5.796e-77	267.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi,27XNS@189775|Thermomicrobia	189775|Thermomicrobia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS3_k127_104309_4	1121090.KB894694_gene2132	1.486e-69	245.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,1ZCWA@1386|Bacillus	91061|Bacilli	E	COG1177 ABC-type spermidine putrescine transport system, permease component II	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS3_k127_104309_1	670487.Ocepr_0988	1.395e-95	324.0	COG0687@1|root,COG0687@2|Bacteria,1WIQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CMS3_k127_1073690_0	522306.CAP2UW1_3003	4.338e-285	903.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2VJYR@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5110,Glyco_hydro_31
CMS3_k127_1073690_1	1200792.AKYF01000010_gene1879	2.789e-50	182.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,26QE9@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS3_k127_1082443_0	926569.ANT_13240	5.255e-132	432.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS3_k127_1082443_1	479434.Sthe_1446	7.032e-48	188.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
CMS3_k127_1089525_0	926569.ANT_20420	4.932e-284	902.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS3_k127_1089525_4	671143.DAMO_2882	3.92e-61	221.0	COG0668@1|root,COG0668@2|Bacteria,2NPY4@2323|unclassified Bacteria	2|Bacteria	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
CMS3_k127_1089525_5	937777.Deipe_0816	2.9e-53	190.0	COG1250@1|root,COG1250@2|Bacteria,1WIPA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_1089525_6	235909.GK3395	3.592e-34	136.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1WFG8@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_1089525_2	1118054.CAGW01000053_gene1509	4.174e-81	278.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,26UEW@186822|Paenibacillaceae	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_1089525_3	880072.Desac_2808	8.719e-81	281.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,2MRAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS3_k127_1089525_7	926560.KE387027_gene896	2.044e-20	103.0	COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
CMS3_k127_1089525_1	926569.ANT_14030	1.695e-213	683.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_109739_11	3983.cassava4.1_002244m	1.35e-13	72.0	COG1506@1|root,KOG2281@2759|Eukaryota,37N3A@33090|Viridiplantae,3GGFF@35493|Streptophyta,4JJGP@91835|fabids	35493|Streptophyta	O	Dipeptidyl peptidase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_109739_0	329726.AM1_2452	8.774e-248	814.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_109739_2	1128421.JAGA01000002_gene285	4.27e-58	218.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_109739_5	743718.Isova_1995	7.906e-31	132.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4F4RF@85017|Promicromonosporaceae	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS3_k127_109739_10	1123058.KB894243_gene1265	1.016e-13	75.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
CMS3_k127_109739_3	926550.CLDAP_14940	4.011e-57	205.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_109739_13	476272.RUMHYD_00821	7.111e-05	51.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,3XZUX@572511|Blautia	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
CMS3_k127_109739_6	118166.JH976537_gene1454	1.422e-29	124.0	COG1853@1|root,COG1853@2|Bacteria,1G2RV@1117|Cyanobacteria,1H7U3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_109739_4	926550.CLDAP_23450	1.849e-38	154.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS3_k127_109739_1	880073.Calab_3094	8.162e-116	384.0	COG2730@1|root,COG2730@2|Bacteria,2NPWE@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,Cellulase
CMS3_k127_109739_9	1122138.AQUZ01000013_gene5691	2.705e-18	96.0	COG0627@1|root,COG1520@1|root,COG0627@2|Bacteria,COG1520@2|Bacteria,2GJX4@201174|Actinobacteria,4DQ66@85009|Propionibacteriales	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_109739_7	204669.Acid345_2313	2.052e-26	117.0	2AZDP@1|root,31RMA@2|Bacteria,3Y4JB@57723|Acidobacteria,2JJ76@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
CMS3_k127_109739_8	765420.OSCT_2975	2.319e-20	93.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi,375YB@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
CMS3_k127_109739_12	1111479.AXAR01000007_gene991	6.181e-07	61.0	COG0318@1|root,COG0318@2|Bacteria,1V2NE@1239|Firmicutes,4HBPA@91061|Bacilli	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1114875_5	321327.CYA_0418	2.46e-21	99.0	COG1357@1|root,COG1357@2|Bacteria,1G32J@1117|Cyanobacteria,1H1RC@1129|Synechococcus	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_1114875_4	264732.Moth_0704	4.652e-24	110.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,42FQD@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Class II aldolase adducin	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS3_k127_1114875_1	1120973.AQXL01000135_gene1401	7.059e-87	296.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,4HAGP@91061|Bacilli,277WT@186823|Alicyclobacillaceae	91061|Bacilli	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_1114875_3	1396141.BATP01000058_gene1962	3.315e-24	109.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2,LigT_PEase
CMS3_k127_1114875_2	251229.Chro_5489	6.425e-84	293.0	COG2816@1|root,COG2816@2|Bacteria,1G3EM@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the Nudix hydrolase family. NudC subfamily	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
CMS3_k127_1114875_0	383372.Rcas_3820	1.99e-109	376.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_1117168_0	926550.CLDAP_20090	5.229e-141	459.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3585	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
CMS3_k127_1117168_1	926550.CLDAP_20100	1.029e-22	102.0	COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi	200795|Chloroflexi	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS3_k127_111846_4	187272.Mlg_2081	1.092e-19	99.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1WW7R@135613|Chromatiales	135613|Chromatiales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS3_k127_111846_5	1123024.AUII01000012_gene4116	0.0001251	51.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DXNB@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
CMS3_k127_111846_0	926550.CLDAP_02840	2.972e-130	429.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS3_k127_111846_3	926569.ANT_03770	5.2e-68	237.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
CMS3_k127_111846_2	926569.ANT_03780	4.888e-72	253.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	2|Bacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_111846_1	926550.CLDAP_11790	2.343e-96	337.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_1119441_2	765420.OSCT_2044	9.447e-37	153.0	2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi,375QK@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
CMS3_k127_1119441_0	1128421.JAGA01000002_gene1058	2.482e-129	420.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_1119441_1	926550.CLDAP_30340	3.538e-111	369.0	COG1721@1|root,COG1721@2|Bacteria,2G7PU@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_1122214_0	795955.AFRW01000025_gene2319	3.952e-24	115.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,1W8U3@1268|Micrococcaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_1122214_1	1206732.BAGD01000099_gene4397	3.414e-22	106.0	COG0501@1|root,COG0501@2|Bacteria,2GKJQ@201174|Actinobacteria,4FY5K@85025|Nocardiaceae	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_1122214_2	324925.Ppha_0070	1.574e-14	87.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	3.4.24.21	ko:K08076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Astacin
CMS3_k127_1127017_0	880073.Calab_1286	1.96e-29	138.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
CMS3_k127_1136842_1	103733.JNYO01000001_gene69	1.903e-24	121.0	COG1132@1|root,COG2319@1|root,COG1132@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4DZJG@85010|Pseudonocardiales	201174|Actinobacteria	T	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
CMS3_k127_1136842_0	522306.CAP2UW1_2609	8.435e-89	327.0	COG1192@1|root,COG1357@1|root,COG1787@1|root,COG2319@1|root,COG5635@1|root,COG1192@2|Bacteria,COG1357@2|Bacteria,COG1787@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
CMS3_k127_1145813_2	926550.CLDAP_22650	6.417e-97	322.0	COG4947@1|root,COG4947@2|Bacteria	2|Bacteria	P	esterase	XK27_05675	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_1145813_1	1210884.HG799465_gene12056	7.544e-147	470.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1145813_0	1210884.HG799465_gene12055	4.464e-167	537.0	COG2308@1|root,COG2308@2|Bacteria	2|Bacteria	S	glutamate-cysteine ligase activity	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	CP_ATPgrasp_2,GSP_synth
CMS3_k127_1146072_0	479434.Sthe_1284	1.102e-154	501.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,27XGH@189775|Thermomicrobia	189775|Thermomicrobia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	-	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS3_k127_1146072_1	926569.ANT_09460	7.19e-14	78.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
CMS3_k127_1154796_2	926569.ANT_05740	1.193e-69	244.0	COG0702@1|root,COG0702@2|Bacteria,2G78J@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
CMS3_k127_1154796_4	1158294.JOMI01000009_gene916	2.362e-43	162.0	COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,2FT28@200643|Bacteroidia	976|Bacteroidetes	J	MazG nucleotide pyrophosphohydrolase domain protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS3_k127_1154796_7	404589.Anae109_2639	1.854e-22	107.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_1154796_9	926569.ANT_31290	2.54e-13	81.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
CMS3_k127_1154796_5	653045.Strvi_1773	3.556e-35	139.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_1154796_8	543526.Htur_3573	1.225e-16	91.0	COG2141@1|root,arCOG02410@2157|Archaea,2XTN9@28890|Euryarchaeota,23T1C@183963|Halobacteria	183963|Halobacteria	C	Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT	mer	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
CMS3_k127_1154796_1	1304865.JAGF01000001_gene110	1.873e-112	371.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4F1PI@85016|Cellulomonadaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_1154796_6	1089551.KE386572_gene1161	4.621e-28	120.0	2DP4V@1|root,330IZ@2|Bacteria,1QZDT@1224|Proteobacteria,2TYEK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1154796_3	357808.RoseRS_3845	1.488e-56	227.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1154796_0	63737.Npun_F1222	2.25e-168	571.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS3_k127_115976_6	316274.Haur_3376	6.227e-33	139.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	yfkC	GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
CMS3_k127_115976_7	1150864.MILUP08_45463	0.0005343	46.0	2APGC@1|root,31EJ6@2|Bacteria,2GWJ9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
CMS3_k127_115976_3	926550.CLDAP_08440	9.823e-79	269.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_115976_4	926550.CLDAP_08450	5.515e-42	169.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G96Q@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
CMS3_k127_115976_2	926550.CLDAP_05170	1.42e-87	299.0	COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
CMS3_k127_115976_0	926569.ANT_06070	1.732e-134	439.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_115976_5	1395587.P364_0125015	3.371e-39	152.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,26U28@186822|Paenibacillaceae	91061|Bacilli	T	PFAM response regulator receiver	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_115976_1	1385935.N836_10600	1.271e-95	322.0	COG0668@1|root,COG0668@2|Bacteria,1G06A@1117|Cyanobacteria	1117|Cyanobacteria	M	COG0668 Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS3_k127_1160540_6	926550.CLDAP_06280	2.454e-72	248.0	COG2141@1|root,COG3255@1|root,COG2141@2|Bacteria,COG3255@2|Bacteria,2G878@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_1160540_16	1121946.AUAX01000021_gene8120	1.449e-14	79.0	2ED92@1|root,3375I@2|Bacteria,2GU8M@201174|Actinobacteria,4DG7G@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1160540_5	1173024.KI912151_gene1879	5.582e-90	305.0	COG1028@1|root,COG1028@2|Bacteria,1G02R@1117|Cyanobacteria,1JK3B@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1160540_14	195250.CM001776_gene434	6.447e-24	105.0	COG1669@1|root,COG1669@2|Bacteria,1G6K9@1117|Cyanobacteria,1H1J2@1129|Synechococcus	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS3_k127_1160540_11	1173027.Mic7113_5194	4.675e-26	110.0	COG2361@1|root,COG2361@2|Bacteria,1G80M@1117|Cyanobacteria,1HCPE@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS3_k127_1160540_2	926569.ANT_05360	2.944e-179	578.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
CMS3_k127_1160540_9	518766.Rmar_0039	2.3e-53	196.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1FK5D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_1160540_7	926550.CLDAP_38410	2.936e-72	254.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_1160540_1	926569.ANT_15160	4.609e-202	649.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
CMS3_k127_1160540_10	765420.OSCT_2729	1.518e-46	182.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi,375G5@32061|Chloroflexia	32061|Chloroflexia	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_1160540_8	1521187.JPIM01000053_gene2947	4.971e-69	250.0	COG2304@1|root,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi,374V6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_1160540_13	324602.Caur_3814	9.952e-26	114.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_1160540_15	479434.Sthe_1247	1.76e-19	90.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi,27YRF@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1160540_4	1128421.JAGA01000003_gene3596	2.887e-105	347.0	COG0745@1|root,COG0745@2|Bacteria,2NR2D@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1160540_3	926550.CLDAP_39810	1.23e-129	441.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi	200795|Chloroflexi	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS3_k127_1160540_12	345073.VC395_A0072	8.619e-26	110.0	COG0296@1|root,COG0296@2|Bacteria,1N8WX@1224|Proteobacteria,1SG9V@1236|Gammaproteobacteria,1XY0F@135623|Vibrionales	135623|Vibrionales	G	PFAM glycoside hydrolase, family 13	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
CMS3_k127_1160540_0	926569.ANT_23100	0.0	1258.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_1173283_1	1499686.BN1079_00582	1.613e-50	186.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Hydroxymethylglutaryl-CoA lyase	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_1173283_0	1122176.KB903533_gene2292	4.621e-118	404.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF1929,Kelch_1,Kelch_4,Kelch_5,Laminin_G_3,Malectin,Peptidase_C1,Peptidase_S8,SLH
CMS3_k127_1174158_2	357808.RoseRS_1088	1.198e-18	95.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1174158_0	1128421.JAGA01000001_gene2388	7.823e-44	170.0	COG0745@1|root,COG0745@2|Bacteria	1128421.JAGA01000001_gene2388|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1174158_3	1037409.BJ6T_49390	3.35e-11	73.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JRJI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_3,PAS_9
CMS3_k127_1174158_1	383372.Rcas_0886	1.271e-22	104.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg
CMS3_k127_1178551_0	335543.Sfum_4007	9.027e-08	63.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
CMS3_k127_1178551_1	880073.Calab_3213	3.708e-06	59.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Arylsulfotrans,PQQ_2
CMS3_k127_1179535_1	1121377.KB906400_gene1412	5.049e-09	69.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_1179535_0	1403819.BATR01000022_gene806	1.043e-34	139.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_1187223_0	926550.CLDAP_07340	0.0	1037.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_1187223_2	357808.RoseRS_2229	6.226e-82	292.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1187223_1	926569.ANT_15670	7.135e-86	312.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1187223_3	525904.Tter_1002	5.601e-57	206.0	COG1974@1|root,COG1974@2|Bacteria,2NPJG@2323|unclassified Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS3_k127_1187223_4	926550.CLDAP_25450	2.29e-25	112.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	2|Bacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_1188054_0	469371.Tbis_2599	3.227e-238	743.0	COG1032@1|root,COG1032@2|Bacteria,2HW71@201174|Actinobacteria,4E7P4@85010|Pseudonocardiales	201174|Actinobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_119579_1	1254432.SCE1572_04150	4.296e-43	165.0	COG1670@1|root,COG1670@2|Bacteria,1RKT9@1224|Proteobacteria,42VCK@68525|delta/epsilon subdivisions,2WS7R@28221|Deltaproteobacteria,2Z14V@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	rimJ2	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS3_k127_119579_0	926550.CLDAP_24680	8.418e-160	521.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1202714_0	926550.CLDAP_20570	7.485e-75	257.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
CMS3_k127_120823_1	373903.Hore_14640	2.376e-91	311.0	COG0330@1|root,COG0330@2|Bacteria,1W711@1239|Firmicutes,25IRK@186801|Clostridia,3WC5Y@53433|Halanaerobiales	186801|Clostridia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_120823_0	926550.CLDAP_17400	3.112e-103	349.0	COG1355@1|root,COG1355@2|Bacteria,2G835@200795|Chloroflexi	200795|Chloroflexi	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS3_k127_120823_2	1122611.KB903974_gene3052	3.885e-76	274.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4EHXV@85012|Streptosporangiales	201174|Actinobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS3_k127_120823_3	522306.CAP2UW1_2629	2.764e-14	83.0	COG1502@1|root,COG1716@1|root,COG1502@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.8.8	ko:K00998,ko:K06131	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800,R07390	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,PLDc_2,Yop-YscD_cpl
CMS3_k127_120823_4	309801.trd_0671	1.029e-09	70.0	COG1555@1|root,COG1555@2|Bacteria,2G9V4@200795|Chloroflexi,27YJ5@189775|Thermomicrobia	189775|Thermomicrobia	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS3_k127_1209176_2	1298858.AUEL01000007_gene2472	3.289e-08	55.0	COG0500@1|root,COG2226@2|Bacteria,1RJPA@1224|Proteobacteria,2TZCG@28211|Alphaproteobacteria,43P48@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_1209176_0	349521.HCH_04893	1.83e-86	297.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1XR4N@135619|Oceanospirillales	135619|Oceanospirillales	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_1209176_1	1120959.ATXF01000004_gene3090	9.342e-11	69.0	COG0645@1|root,COG0645@2|Bacteria,2IKMM@201174|Actinobacteria,4FPHX@85023|Microbacteriaceae	201174|Actinobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS3_k127_1224059_0	1278073.MYSTI_01483	1.487e-152	496.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2YUCW@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS3_k127_1224059_2	765420.OSCT_1325	3.012e-71	253.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi,375H7@32061|Chloroflexia	32061|Chloroflexia	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
CMS3_k127_1224059_1	316274.Haur_1217	8.066e-98	345.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_1224059_4	316274.Haur_1217	6.638e-38	159.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_1224059_9	1385513.N780_02780	4.063e-10	72.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,4ISWH@91061|Bacilli,2Y9YA@289201|Pontibacillus	91061|Bacilli	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
CMS3_k127_1224059_5	926569.ANT_11820	1.721e-31	145.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
CMS3_k127_1224059_6	926569.ANT_11780	1.902e-21	112.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_1224059_10	1502852.FG94_02658	9.643e-08	67.0	COG3829@1|root,COG3829@2|Bacteria,1QW3X@1224|Proteobacteria,2WHGD@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1224059_3	1095769.CAHF01000011_gene2568	1.279e-70	274.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_3
CMS3_k127_1224059_7	926569.ANT_11810	2.566e-19	105.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
CMS3_k127_1224059_8	32057.KB217478_gene4842	3.477e-14	88.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1HKYA@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
CMS3_k127_122652_0	344747.PM8797T_15883	2.994e-69	258.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,2IXUA@203682|Planctomycetes	203682|Planctomycetes	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
CMS3_k127_122652_1	1120985.AUMI01000016_gene1829	9.489e-45	188.0	COG0251@1|root,COG0251@2|Bacteria,1VT5Z@1239|Firmicutes	1239|Firmicutes	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_123055_0	926550.CLDAP_01280	6.149e-110	370.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_123055_1	1128421.JAGA01000001_gene2133	4.068e-44	168.0	COG3275@1|root,COG3275@2|Bacteria,2NR98@2323|unclassified Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.65	ko:K16923,ko:K18967	-	M00582	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.28,9.B.34.1.1	-	-	5TM-5TMR_LYT,ECF_trnsprt,GGDEF,HATPase_c,PAS_4,PAS_7
CMS3_k127_1240348_3	380703.AHA_2697	1.957e-21	110.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1Y5TP@135624|Aeromonadales	135624|Aeromonadales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS3_k127_1240348_7	247639.MGP2080_09933	8.238e-05	49.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MU7M@1224|Proteobacteria,1RP7W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	fad dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS3_k127_1240348_8	1217720.ALOX01000198_gene938	0.0006317	43.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2U9U2@28211|Alphaproteobacteria,2JQ4Q@204441|Rhodospirillales	204441|Rhodospirillales	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
CMS3_k127_1240348_5	1040989.AWZU01000014_gene4629	1e-12	74.0	COG3436@1|root,COG3436@2|Bacteria,1RHDW@1224|Proteobacteria,2U7TH@28211|Alphaproteobacteria,3JZ4X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	IS66 Orf2	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
CMS3_k127_1240348_1	391612.CY0110_03084	5.356e-94	328.0	2B8KV@1|root,321W5@2|Bacteria,1GMTM@1117|Cyanobacteria,3KKAC@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1240348_2	479434.Sthe_0243	3.636e-65	230.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_1240348_4	301.JNHE01000002_gene2354	1.468e-16	85.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1YEYN@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
CMS3_k127_1240348_6	269799.Gmet_2629	1.52e-07	61.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2629	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_1240348_0	383372.Rcas_3701	6.321e-138	480.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS3_k127_1242968_2	1123072.AUDH01000001_gene3010	1.273e-17	83.0	COG1335@1|root,COG1335@2|Bacteria,1NZJ1@1224|Proteobacteria,2V93V@28211|Alphaproteobacteria,2JWZP@204441|Rhodospirillales	204441|Rhodospirillales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS3_k127_1242968_3	1046724.KB889881_gene1782	8.641e-09	62.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria,469JA@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_1242968_1	443144.GM21_4084	2.683e-64	237.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_1242968_0	1128421.JAGA01000003_gene3678	4.801e-125	441.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS3_k127_1242968_4	869213.JCM21142_93374	3.436e-06	55.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47Y22@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS3_k127_1242968_5	631454.N177_0114	8.888e-06	57.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2TU29@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	PBS lyase HEAT domain protein repeat-containing protein	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_124567_0	1173024.KI912149_gene6343	8.824e-158	514.0	COG0659@1|root,COG0659@2|Bacteria,1G0NU@1117|Cyanobacteria	1117|Cyanobacteria	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS3_k127_124567_1	76114.ebD26	1.045e-43	164.0	COG2020@1|root,COG2020@2|Bacteria,1QVIW@1224|Proteobacteria,2VX8F@28216|Betaproteobacteria	28216|Betaproteobacteria	O	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_1246645_2	765420.OSCT_2820	1e-26	124.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi,374UJ@32061|Chloroflexia	32061|Chloroflexia	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_6,TPR_7,TPR_8
CMS3_k127_1246645_0	926569.ANT_18090	8.552e-114	375.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi	200795|Chloroflexi	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_1246645_1	926569.ANT_15980	1.553e-53	201.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1252854_2	866536.Belba_0903	0.000946	44.0	COG0249@1|root,COG0249@2|Bacteria,4NE6X@976|Bacteroidetes,47KGC@768503|Cytophagia	976|Bacteroidetes	L	PFAM DNA mismatch repair protein MutS	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
CMS3_k127_1252854_1	485913.Krac_11786	6.943e-07	58.0	COG0249@1|root,COG0249@2|Bacteria,2G8CJ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA mismatch repair protein MutS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
CMS3_k127_1252854_0	383372.Rcas_0019	4.093e-118	386.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,376ZQ@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_1255929_1	657322.FPR_17720	3.185e-67	235.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WGB8@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1255929_3	861299.J421_3195	9.268e-42	159.0	COG0251@1|root,COG0251@2|Bacteria,1ZTSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS3_k127_1255929_0	926569.ANT_25310	1.777e-72	257.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
CMS3_k127_1255929_2	926569.ANT_25300	1.13e-52	197.0	COG2888@1|root,COG2888@2|Bacteria	2|Bacteria	J	peptidyl-tyrosine sulfation	ybeL	-	1.17.4.1,4.6.1.1	ko:K00525,ko:K01768	ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213	M00053,M00695	R00089,R00434,R02017,R02018,R02019,R02024	RC00295,RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	DUF1451
CMS3_k127_1255929_4	1128421.JAGA01000003_gene3091	9.988e-28	130.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_1256146_1	1487953.JMKF01000043_gene2591	4.71e-67	239.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
CMS3_k127_1256146_0	324602.Caur_1076	1.387e-77	274.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi,37780@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS3_k127_1256146_2	665571.STHERM_c13920	9.544e-50	189.0	COG1175@1|root,COG1175@2|Bacteria,2JAFT@203691|Spirochaetes	203691|Spirochaetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS3_k127_126330_3	216594.MMAR_0921	1.929e-41	167.0	COG0577@1|root,COG0577@2|Bacteria,2I5G9@201174|Actinobacteria,23906@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CMS3_k127_126330_0	1128421.JAGA01000001_gene2241	1.51e-75	260.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_126330_4	316274.Haur_0626	2.863e-32	133.0	COG1309@1|root,COG1309@2|Bacteria,2G8XR@200795|Chloroflexi,377W5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_126330_2	1437882.AZRU01000024_gene5817	1.148e-54	195.0	COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,1S480@1236|Gammaproteobacteria,1YG26@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
CMS3_k127_126330_5	1122221.JHVI01000019_gene1152	4.312e-28	125.0	COG0491@1|root,COG0491@2|Bacteria,1WI41@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_126330_6	1273538.G159_09065	6.478e-23	101.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,26G4B@186818|Planococcaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
CMS3_k127_126330_1	926550.CLDAP_36010	6.84e-70	249.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.5.1.28	ko:K01448,ko:K07448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036	-	-	-	Muraidase,SH3_3,SLH
CMS3_k127_1265750_2	316274.Haur_2170	5.852e-40	165.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_1265750_1	1134912.AJTV01000014_gene245	4.296e-53	195.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2U895@28211|Alphaproteobacteria,3716P@31993|Methylocystaceae	28211|Alphaproteobacteria	KT	helix_turn_helix, Lux Regulon	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_1265750_0	1313421.JHBV01000030_gene2244	5.86e-68	242.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_32,PCMT
CMS3_k127_1265750_3	272557.APE_0511.1	3.033e-22	100.0	COG0430@1|root,arCOG04125@2157|Archaea,2XPT6@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
CMS3_k127_1271945_1	926569.ANT_30540	6.416e-100	336.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1271945_4	1440053.JOEI01000007_gene2532	7.186e-05	53.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_1271945_3	637910.ROD_25861	1.701e-13	79.0	COG0741@1|root,COG0741@2|Bacteria,1PGGN@1224|Proteobacteria,1RX0H@1236|Gammaproteobacteria,3WZNC@544|Citrobacter	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS3_k127_1271945_0	1385511.N783_07635	6.949e-136	451.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
CMS3_k127_1276162_0	118173.KB235910_gene4409	6.622e-12	80.0	COG0457@1|root,COG0457@2|Bacteria,1GQEI@1117|Cyanobacteria,1HI2Q@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
CMS3_k127_1277475_0	1382306.JNIM01000001_gene1873	6.77e-67	259.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
CMS3_k127_1277475_4	1519464.HY22_06675	5.115e-05	51.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,AhpC-TSA_2
CMS3_k127_1277475_1	357808.RoseRS_2229	1.125e-56	220.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1277475_3	324602.Caur_0300	1.311e-10	66.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1277475_2	324602.Caur_0299	4.043e-30	132.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_1280808_2	1128421.JAGA01000002_gene1823	5.054e-26	119.0	COG3688@1|root,COG3688@2|Bacteria,2NQ5V@2323|unclassified Bacteria	2|Bacteria	S	YacP-like NYN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_IV,GTP_EFTU,NYN_YacP
CMS3_k127_1280808_0	717605.Theco_0215	4.471e-159	524.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,26QTI@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_1283169_4	1128421.JAGA01000001_gene2427	4.461e-34	138.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2NPBQ@2323|unclassified Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	hemD	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.107,2.5.1.61,4.2.1.75	ko:K01719,ko:K01749,ko:K02303,ko:K13542,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084,R03165,R03194	RC00003,RC00871,RC01861,RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755,iJN678.hemD	HEM4,TP_methylase
CMS3_k127_1283169_0	1128421.JAGA01000001_gene2426	6.358e-144	463.0	COG0113@1|root,COG0113@2|Bacteria,2NNST@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ALAD family	hemB	GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iECABU_c1320.ECABU_c04500,iEcSMS35_1347.EcSMS35_0398,iJN746.PP_2913,ic_1306.c0477	ALAD
CMS3_k127_1283169_3	926550.CLDAP_19070	3.408e-109	358.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
CMS3_k127_1283169_2	1121382.JQKG01000073_gene2574	3.882e-126	417.0	COG0407@1|root,COG0407@2|Bacteria,1WIHR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS3_k127_1283169_1	546414.Deide_05290	1.854e-126	411.0	COG0276@1|root,COG0276@2|Bacteria,1WJEA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS3_k127_1285116_6	111781.Lepto7376_0894	3.425e-24	117.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1GBAY@1117|Cyanobacteria	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS3_k127_1285116_5	573370.DMR_01690	2.063e-28	117.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MGUH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_1285116_3	234267.Acid_5780	3.269e-119	424.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
CMS3_k127_1285116_2	765910.MARPU_00280	2.88e-119	396.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales	135613|Chromatiales	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
CMS3_k127_1285116_9	1123020.AUIE01000001_gene2169	7.673e-16	84.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1T1GB@1236|Gammaproteobacteria,1YDMM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	HPP family	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
CMS3_k127_1285116_4	626887.J057_20310	8.888e-83	291.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,464T6@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	cyaB	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,MASE2
CMS3_k127_1285116_7	439496.RBY4I_2761	1.799e-23	103.0	COG2346@1|root,COG2346@2|Bacteria,1Q6XQ@1224|Proteobacteria,2U9CB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_1285116_8	926569.ANT_02590	7.139e-18	90.0	COG1846@1|root,COG1846@2|Bacteria,2G9M0@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1285116_1	608506.COB47_0200	2.304e-238	758.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,42FRT@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1285116_0	744872.Spica_0302	2.909e-273	856.0	COG1132@1|root,COG1132@2|Bacteria,2J5W8@203691|Spirochaetes	203691|Spirochaetes	V	ABC transporter	-	-	-	ko:K06147,ko:K11085,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1289764_2	926550.CLDAP_35070	4.657e-106	377.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3275@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_1289764_1	937777.Deipe_1849	3.251e-165	524.0	COG0451@1|root,COG0451@2|Bacteria,1WM05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_1289764_10	861299.J421_0989	3.429e-10	72.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSZA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_1289764_6	926569.ANT_19350	1.761e-45	184.0	COG0642@1|root,COG3283@1|root,COG2205@2|Bacteria,COG3283@2|Bacteria	2|Bacteria	EK	Transcriptional regulator of aromatic amino acids metabolism	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	ANTAR,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,LytTR,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_1289764_4	926569.ANT_19360	8.342e-65	231.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_19360|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1289764_0	671143.DAMO_0766	1.302e-178	580.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	pcmB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	ko:K03388,ko:K12527	ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R07229,R11928,R11931,R11943,R11944	RC00011,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,FlpD,Pyr_redox_2,Pyr_redox_3
CMS3_k127_1289764_5	1123355.JHYO01000017_gene3613	6.467e-56	215.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,2UA53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_1289764_3	671143.DAMO_0768	3.629e-86	295.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS3_k127_1289764_7	671143.DAMO_0768	3.349e-39	156.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS3_k127_1289764_8	765420.OSCT_2992	1.441e-35	141.0	COG0723@1|root,COG0723@2|Bacteria,2GB28@200795|Chloroflexi,377SJ@32061|Chloroflexia	32061|Chloroflexia	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS3_k127_1289764_9	765420.OSCT_2991	2.492e-31	137.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K00406,ko:K03889,ko:K17222,ko:K19713	ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3
CMS3_k127_1313477_0	1499967.BAYZ01000013_gene6421	3.968e-81	276.0	COG1012@1|root,COG1012@2|Bacteria,2NQI9@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	eutE	GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.87	ko:K04021,ko:K13922	ko00620,ko00640,ko01100,ko01120,map00620,map00640,map01100,map01120	-	R00228,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_1313477_1	324602.Caur_3799	6.938e-39	159.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
CMS3_k127_1313477_3	1117108.PAALTS15_01757	5.851e-14	80.0	COG4577@1|root,COG4577@2|Bacteria,1V8TU@1239|Firmicutes,4HK9C@91061|Bacilli,26X8H@186822|Paenibacillaceae	91061|Bacilli	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
CMS3_k127_1313477_2	502025.Hoch_4425	5.786e-21	99.0	COG4576@1|root,COG4576@2|Bacteria,1Q0YX@1224|Proteobacteria,434YC@68525|delta/epsilon subdivisions,2WZ99@28221|Deltaproteobacteria,2Z1MJ@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
CMS3_k127_1322482_1	443143.GM18_3946	1.508e-45	173.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,43W1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1322482_2	926569.ANT_24800	1.749e-45	171.0	COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_1322482_0	234267.Acid_7897	8.598e-114	393.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1322482_3	1487953.JMKF01000045_gene2870	7.828e-30	128.0	COG1802@1|root,COG1802@2|Bacteria,1G2P5@1117|Cyanobacteria,1HHM7@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS3_k127_1324115_4	35754.JNYJ01000009_gene1932	3.143e-34	133.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4DJEC@85008|Micromonosporales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
CMS3_k127_1324115_0	926550.CLDAP_34680	4.973e-78	279.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS3_k127_1324115_1	1384056.N787_06875	6.26e-75	262.0	arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1324115_3	84531.JMTZ01000104_gene1645	2.556e-63	233.0	COG1571@1|root,COG1571@2|Bacteria,1QVS8@1224|Proteobacteria,1T2IQ@1236|Gammaproteobacteria,1X9DX@135614|Xanthomonadales	135614|Xanthomonadales	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1324115_6	1449351.RISW2_19730	6.169e-10	71.0	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,2U0YM@28211|Alphaproteobacteria,4KM5N@93682|Roseivivax	28211|Alphaproteobacteria	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	zf-RRN7
CMS3_k127_1324115_5	1121106.JQKB01000032_gene4450	4.796e-33	135.0	COG0454@1|root,COG0456@2|Bacteria,1N6QA@1224|Proteobacteria,2UFGS@28211|Alphaproteobacteria,2JUES@204441|Rhodospirillales	204441|Rhodospirillales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_1324115_2	479434.Sthe_0653	1.024e-67	239.0	COG0284@1|root,COG0284@2|Bacteria,2G692@200795|Chloroflexi,27XX0@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS3_k127_1329860_3	1449355.JQNR01000003_gene830	2.916e-23	104.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria	201174|Actinobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
CMS3_k127_1329860_1	383372.Rcas_3796	9.307e-157	505.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,376PX@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
CMS3_k127_1329860_2	926550.CLDAP_24420	6.623e-25	106.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi	200795|Chloroflexi	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
CMS3_k127_1329860_0	926569.ANT_17860	8.204e-198	634.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
CMS3_k127_1338170_3	926569.ANT_04290	1.92e-22	105.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_1338170_2	765420.OSCT_1613	8.729e-47	177.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_1338170_1	1227497.C491_20342	7.603e-54	199.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
CMS3_k127_1338170_0	1415780.JPOG01000001_gene2678	7.483e-61	222.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1X4ZD@135614|Xanthomonadales	135614|Xanthomonadales	U	secretion system protein	-	-	-	ko:K02283,ko:K20527	ko02024,map02024	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.7.4	-	-	FHA,T2SSE
CMS3_k127_1344313_1	383372.Rcas_2261	9.971e-44	165.0	COG0438@1|root,COG0438@2|Bacteria,2G82G@200795|Chloroflexi,375AN@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
CMS3_k127_1344313_0	1348657.M622_18225	1.194e-44	180.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2VVMC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1346518_5	518766.Rmar_1668	6.578e-36	140.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes	976|Bacteroidetes	H	Uroporphyrin-III C-methyltransferase	cobA	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CMS3_k127_1346518_1	1089550.ATTH01000001_gene1867	1.362e-83	284.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,1FJG5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS3_k127_1346518_3	518766.Rmar_1669	2.677e-61	220.0	COG1648@1|root,COG1648@2|Bacteria	2|Bacteria	H	precorrin-2 dehydrogenase activity	cysG	GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_3507,iECSE_1348.ECSE_3630,iEcE24377_1341.EcE24377A_3838,iJN746.PP_3999,iPC815.YPO0158	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS3_k127_1346518_0	1385935.N836_19565	5.102e-102	349.0	COG0477@1|root,COG0477@2|Bacteria,1GHCR@1117|Cyanobacteria,1H7ZA@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS3_k127_1346518_4	886293.Sinac_7157	4.763e-44	165.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	ftn	GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771	1.16.3.1,1.16.3.2	ko:K02217,ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS3_k127_1346518_2	1227454.C446_09730	2.525e-66	243.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_1346518_6	926550.CLDAP_08400	9.346e-36	154.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	2|Bacteria	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12
CMS3_k127_135520_1	1499967.BAYZ01000052_gene4665	3.612e-09	61.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_135520_0	335541.Swol_1622	2.417e-50	198.0	COG2199@1|root,COG3706@2|Bacteria,1TR5R@1239|Firmicutes,24E9M@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
CMS3_k127_1356228_1	429009.Adeg_1311	1.478e-29	138.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_1356228_0	1265505.ATUG01000002_gene1171	4.305e-88	326.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,434EE@68525|delta/epsilon subdivisions,2WYRT@28221|Deltaproteobacteria,2MN3I@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS3_k127_1356228_2	529818.AMSG_09920T0	8.374e-17	82.0	COG2114@1|root,KOG0618@2759|Eukaryota	2759|Eukaryota	T	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CH,Guanylate_cyc,Laminin_G_3
CMS3_k127_136895_0	373994.Riv7116_6382	6.695e-109	367.0	COG4715@1|root,COG4715@2|Bacteria,1G4AG@1117|Cyanobacteria,1HS1Y@1161|Nostocales	1117|Cyanobacteria	S	Swim zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS3_k127_136895_1	765420.OSCT_1306	6.15e-38	152.0	COG5094@1|root,COG5094@2|Bacteria,2G8TY@200795|Chloroflexi	200795|Chloroflexi	K	RNA polymerase II transcriptional preinitiation complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1370706_6	926569.ANT_11560	1.517e-61	222.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1370706_5	309801.trd_1669	1.601e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_1370706_2	926569.ANT_11580	9.041e-75	263.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
CMS3_k127_1370706_1	926569.ANT_20640	2.532e-93	321.0	COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi	200795|Chloroflexi	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
CMS3_k127_1370706_0	926569.ANT_20650	2.345e-192	610.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS3_k127_1370706_4	1382356.JQMP01000003_gene2237	1.294e-69	247.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,27XX2@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS3_k127_1370706_3	926569.ANT_20670	2.515e-72	256.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS3_k127_1370706_7	926550.CLDAP_25350	8.007e-22	102.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi	200795|Chloroflexi	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS3_k127_137327_7	479434.Sthe_0586	1.333e-21	108.0	COG3266@1|root,COG3266@2|Bacteria,2GBHM@200795|Chloroflexi,27Y68@189775|Thermomicrobia	189775|Thermomicrobia	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_137327_10	207559.Dde_1739	0.0001028	47.0	COG3645@1|root,COG3645@2|Bacteria,1NNXV@1224|Proteobacteria	2|Bacteria	S	PFAM Phage P22, antirepressor protein, N-terminal	-	-	-	ko:K07741	-	-	-	-	ko00000	-	-	-	ANT,AntA,KilA-N,ORF11CD3,P22_AR_N
CMS3_k127_137327_8	547045.NEISICOT_01389	6.174e-14	79.0	COG3378@1|root,COG3378@2|Bacteria,1QWAP@1224|Proteobacteria,2VWMG@28216|Betaproteobacteria,2KS75@206351|Neisseriales	206351|Neisseriales	S	P22_AR N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	P22_AR_N
CMS3_k127_137327_3	1283299.AUKG01000001_gene2788	1.94e-48	189.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_137327_5	1121957.ATVL01000006_gene3299	4.137e-44	170.0	COG1028@1|root,COG1028@2|Bacteria,4NTIN@976|Bacteroidetes,47XKW@768503|Cytophagia	976|Bacteroidetes	IQ	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_137327_4	1307761.L21SP2_2777	2.57e-48	186.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	5.99.1.3	ko:K02470,ko:K03833	-	-	-	-	ko00000,ko01000,ko03012,ko03032,ko03400	-	-	-	HATPase_c,HTH_20
CMS3_k127_137327_0	1071679.BG57_05395	4.255e-119	394.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,2W1S8@28216|Betaproteobacteria,1K5IY@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
CMS3_k127_137327_9	219305.MCAG_00054	3.863e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,2GK1K@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	blt	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_137327_1	118166.JH976537_gene881	1.766e-71	250.0	COG2197@1|root,COG2197@2|Bacteria,1G33W@1117|Cyanobacteria,1H6WN@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_137327_2	1122138.AQUZ01000014_gene7126	6.677e-57	216.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_137327_6	1120705.FG95_01036	1.524e-35	153.0	COG1073@1|root,COG1073@2|Bacteria,1R2CS@1224|Proteobacteria,2TZHJ@28211|Alphaproteobacteria,2KBAC@204457|Sphingomonadales	204457|Sphingomonadales	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_137327_11	1210884.HG799463_gene9804	0.0008605	49.0	COG2318@1|root,COG2318@2|Bacteria,2J0AU@203682|Planctomycetes	203682|Planctomycetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_1377485_0	1396418.BATQ01000046_gene6112	1.972e-54	194.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	fprA1	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_1377485_1	349124.Hhal_1518	7.878e-30	130.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WXX2@135613|Chromatiales	135613|Chromatiales	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,OmpA
CMS3_k127_1377485_6	408672.NBCG_05699	2.634e-07	53.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1377485_3	1125701.HMPREF1221_00764	6.408e-21	94.0	2DPM9@1|root,332MQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1377485_2	498761.HM1_3148	1.282e-26	110.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1377485_5	1122619.KB892364_gene1143	1.957e-14	73.0	2EK6X@1|root,33DXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1377485_7	1304875.JAFZ01000002_gene1	1.149e-06	50.0	2DMHR@1|root,32RMI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1377485_4	1121447.JONL01000018_gene3728	4.462e-20	90.0	2DMHR@1|root,32RMI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_13779_1	926569.ANT_13010	5.102e-68	246.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CMS3_k127_13779_0	317619.ANKN01000014_gene2888	2.66e-93	324.0	COG2211@1|root,COG2211@2|Bacteria,1G0ZY@1117|Cyanobacteria,1MKW3@1212|Prochloraceae	1117|Cyanobacteria	P	sugar transporter	melB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS3_k127_13779_2	1150474.JQJI01000011_gene64	1.959e-43	182.0	COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_1384846_12	485918.Cpin_1443	3.233e-12	75.0	COG1020@1|root,COG1020@2|Bacteria,4NE8X@976|Bacteroidetes,1IQK0@117747|Sphingobacteriia	976|Bacteroidetes	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AATase,Condensation
CMS3_k127_1384846_7	195253.Syn6312_1026	1.094e-31	125.0	COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria	1117|Cyanobacteria	S	SPTR CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
CMS3_k127_1384846_9	65093.PCC7418_1802	1.988e-25	108.0	COG2929@1|root,COG2929@2|Bacteria,1G8FA@1117|Cyanobacteria	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS3_k127_1384846_1	926550.CLDAP_34650	4.25e-104	349.0	COG2041@1|root,COG2041@2|Bacteria,2G8K1@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS3_k127_1384846_6	103690.17131108	5.895e-39	151.0	COG1695@1|root,COG1695@2|Bacteria,1G58T@1117|Cyanobacteria,1HRND@1161|Nostocales	1117|Cyanobacteria	K	Virulence activator alpha C-term	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
CMS3_k127_1384846_0	153721.MYP_2783	2.037e-118	399.0	28JBJ@1|root,2Z968@2|Bacteria,4NKZ3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1384846_11	118166.JH976537_gene2074	2.99e-12	74.0	COG5523@1|root,COG5523@2|Bacteria,1G75W@1117|Cyanobacteria,1HCH1@1150|Oscillatoriales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
CMS3_k127_1384846_2	926550.CLDAP_28910	7.282e-81	273.0	COG4122@1|root,COG4122@2|Bacteria,2G97D@200795|Chloroflexi	200795|Chloroflexi	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
CMS3_k127_1384846_4	344747.PM8797T_19764	3.063e-60	215.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS3_k127_1384846_8	32057.KB217480_gene8151	4.346e-27	115.0	2EI1G@1|root,33BSZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1384846_10	1536772.R70723_32055	1.038e-20	104.0	COG0454@1|root,COG0456@2|Bacteria,1UZC5@1239|Firmicutes,4HFDR@91061|Bacilli,26UAI@186822|Paenibacillaceae	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
CMS3_k127_1384846_3	448385.sce7002	6.315e-74	259.0	COG3173@1|root,COG3173@2|Bacteria,1P7JU@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_1384846_5	717774.Marme_0154	3.097e-39	149.0	COG1917@1|root,COG1917@2|Bacteria,1NAFB@1224|Proteobacteria,1SGQB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF861)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_3
CMS3_k127_1388363_4	316274.Haur_3745	1.337e-12	74.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K03281,ko:K08714,ko:K16922	-	-	-	-	ko00000,ko01002,ko02000	1.A.1.14,2.A.49	-	-	CBS,Ion_trans,NTP_transferase,TIR-like,cNMP_binding
CMS3_k127_1388363_3	344747.PM8797T_12803	5.241e-20	102.0	COG1058@1|root,COG1058@2|Bacteria,2IXHK@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS3_k127_1388363_1	644966.Tmar_1195	3.956e-53	204.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,3WD9P@538999|Clostridiales incertae sedis	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1388363_2	765420.OSCT_0607	1.107e-25	111.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi,377JT@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS3_k127_1388363_0	765420.OSCT_0711	7.164e-93	315.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS3_k127_1388889_10	479434.Sthe_0337	0.0004185	44.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CMS3_k127_1388889_8	318829.MGG_10013T0	2.301e-11	77.0	KOG1072@1|root,KOG1072@2759|Eukaryota	2759|Eukaryota	J	protein ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6,NIF
CMS3_k127_1388889_9	1195236.CTER_3436	1.977e-06	61.0	COG1075@1|root,COG1075@2|Bacteria,1VIWR@1239|Firmicutes,24X0F@186801|Clostridia	1239|Firmicutes	S	Lecithin:cholesterol acyltransferase	est	-	-	-	-	-	-	-	-	-	-	-	LCAT,PPC
CMS3_k127_1388889_3	926569.ANT_23180	6.43e-122	403.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi	200795|Chloroflexi	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
CMS3_k127_1388889_2	926569.ANT_23160	4.826e-134	463.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi	200795|Chloroflexi	L	PFAM SMC domain protein	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
CMS3_k127_1388889_1	479434.Sthe_0598	5.371e-136	477.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_1388889_7	521045.Kole_0690	5.697e-23	111.0	COG3868@1|root,COG3868@2|Bacteria,2GEB7@200918|Thermotogae	200918|Thermotogae	S	PFAM TM1410 hypothetical-related protein	-	-	-	ko:K21006	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_114
CMS3_k127_1388889_0	926569.ANT_27120	1.422e-218	703.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
CMS3_k127_1388889_4	1283300.ATXB01000001_gene770	3.554e-48	178.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1XFE1@135618|Methylococcales	135618|Methylococcales	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_1388889_5	1183438.GKIL_4038	9.528e-43	179.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,YARHG,zinc_ribbon_2
CMS3_k127_1388889_6	1121104.AQXH01000001_gene1710	2.282e-36	153.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,1IRAZ@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_1389585_1	316274.Haur_0326	1.889e-102	344.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,374U8@32061|Chloroflexia	32061|Chloroflexia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS3_k127_1389585_3	926569.ANT_18220	1.123e-65	231.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS3_k127_1389585_0	926569.ANT_18230	2.244e-216	690.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
CMS3_k127_1389585_2	926550.CLDAP_35240	1.091e-94	314.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS3_k127_1389585_5	123899.JPQP01000001_gene1660	1.095e-08	61.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,3T86B@506|Alcaligenaceae	28216|Betaproteobacteria	S	Iron-sulphur cluster assembly	iscX	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
CMS3_k127_1389585_4	443143.GM18_2316	1.395e-59	211.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
CMS3_k127_1394011_2	304371.MCP_1301	6.671e-71	261.0	arCOG09180@1|root,arCOG09180@2157|Archaea,2XTAJ@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
CMS3_k127_1394011_0	304371.MCP_1300	8.01e-109	362.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_1394011_3	1499967.BAYZ01000125_gene2599	2.596e-45	171.0	COG1515@1|root,COG1515@2|Bacteria	2|Bacteria	L	deoxyribonuclease V activity	nfi	-	3.1.11.5,3.1.21.7	ko:K01144,ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
CMS3_k127_1394011_1	329726.AM1_4017	5.406e-91	304.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
CMS3_k127_1398047_3	926550.CLDAP_05570	1.361e-89	304.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS3_k127_1398047_7	765420.OSCT_2742	1.307e-56	207.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_1398047_10	994573.T472_0206040	1.353e-20	106.0	2DTR7@1|root,33MCI@2|Bacteria,1W5BS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1398047_14	1196028.ALEF01000025_gene1690	7.259e-10	71.0	COG0596@1|root,COG0596@2|Bacteria,1UTNC@1239|Firmicutes,4HDZI@91061|Bacilli	91061|Bacilli	S	Alpha beta hydrolase	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS3_k127_1398047_9	1089553.Tph_c21870	1.336e-37	158.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS3_k127_1398047_13	1382306.JNIM01000001_gene2399	8.461e-16	85.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS3_k127_1398047_5	926550.CLDAP_20580	8.85e-63	222.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
CMS3_k127_1398047_11	926550.CLDAP_20590	2.269e-20	95.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi	200795|Chloroflexi	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_1398047_4	1499967.BAYZ01000080_gene926	9.756e-82	293.0	COG2234@1|root,COG2234@2|Bacteria,2NQ2F@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_1398047_8	1123274.KB899410_gene3488	3.909e-47	178.0	COG0204@1|root,COG0204@2|Bacteria,2JAHQ@203691|Spirochaetes	203691|Spirochaetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_1398047_6	1123274.KB899410_gene3489	1.122e-62	226.0	COG1597@1|root,COG1597@2|Bacteria,2J9G6@203691|Spirochaetes	203691|Spirochaetes	I	PFAM Diacylglycerol kinase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_1398047_12	1321778.HMPREF1982_01733	1.656e-17	91.0	COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,24HNU@186801|Clostridia,26930@186813|unclassified Clostridiales	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_1398047_0	215803.DB30_4149	1.194e-215	682.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QA7@68525|delta/epsilon subdivisions,2WM2Q@28221|Deltaproteobacteria,2YZTN@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_1398047_2	322710.Avin_00660	4.922e-90	304.0	COG0596@1|root,COG0596@2|Bacteria,1QVQK@1224|Proteobacteria,1RZ4K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
CMS3_k127_1398047_1	69395.JQLZ01000004_gene541	1.622e-154	506.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2V27E@28211|Alphaproteobacteria,2KJ2P@204458|Caulobacterales	204458|Caulobacterales	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS3_k127_139809_1	596151.DesfrDRAFT_1828	1.108e-50	186.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WP9Y@28221|Deltaproteobacteria,2M86H@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_139809_0	1034943.BN1094_00510	1.051e-81	282.0	COG1215@1|root,COG1215@2|Bacteria,1QVTJ@1224|Proteobacteria,1T5HP@1236|Gammaproteobacteria,1JF2C@118969|Legionellales	118969|Legionellales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1402464_0	1122223.KB890700_gene1977	4.689e-143	464.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_1402464_1	357808.RoseRS_3186	2.955e-12	76.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS3_k127_1421735_0	324602.Caur_3678	5.689e-85	291.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,3757F@32061|Chloroflexia	32061|Chloroflexia	J	PFAM ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS3_k127_1421735_2	926550.CLDAP_23770	1.576e-45	181.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_1421735_1	1444309.JAQG01000090_gene1270	9.574e-69	244.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_1421735_5	93059.P9211_07681	2.016e-31	132.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS3_k127_1421735_4	1249997.JHZW01000002_gene1016	9.889e-37	155.0	COG1285@1|root,COG1285@2|Bacteria,4NTPJ@976|Bacteroidetes,1I8N8@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CMS3_k127_1421735_3	143224.JQMD01000002_gene924	1.007e-38	160.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes,1HXYN@117743|Flavobacteriia	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_142295_0	1463820.JOGW01000003_gene7404	5.613e-64	243.0	COG1215@1|root,COG1215@2|Bacteria,2GNYT@201174|Actinobacteria	201174|Actinobacteria	M	GtrA-like protein	dpm	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
CMS3_k127_142295_4	357808.RoseRS_0410	2.284e-07	64.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
CMS3_k127_142295_2	926550.CLDAP_11940	6.139e-43	179.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_142295_1	234267.Acid_1421	3.461e-56	223.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_142295_5	765420.OSCT_1750	0.0007284	46.0	COG1807@1|root,COG1807@2|Bacteria,2GAPY@200795|Chloroflexi,376ZD@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1429548_1	429009.Adeg_0336	9.82e-166	535.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,42EW2@68295|Thermoanaerobacterales	186801|Clostridia	C	CO dehydrogenase acetyl-CoA synthase complex beta subunit	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
CMS3_k127_1429548_0	909663.KI867150_gene97	1.717e-222	710.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
CMS3_k127_1433209_1	1078020.KEK_05957	3.988e-07	56.0	COG0318@1|root,COG0318@2|Bacteria,2I2RH@201174|Actinobacteria,233BE@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Fatty-acid--CoA ligase	-	-	-	ko:K12428	-	-	-	-	ko00000,ko01004	-	-	-	AMP-binding
CMS3_k127_1433209_0	1279038.KB907347_gene3195	7.492e-144	469.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales	204441|Rhodospirillales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_143323_1	765420.OSCT_2479	7.071e-24	113.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi,3758I@32061|Chloroflexia	32061|Chloroflexia	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
CMS3_k127_143323_0	649638.Trad_0672	2.876e-219	691.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,GARS_A,Glu_cys_ligase
CMS3_k127_1448920_1	706587.Desti_1835	3.35e-114	374.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MS4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS3_k127_1448920_0	926569.ANT_05230	1.101e-241	762.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS3_k127_1448920_2	1123278.KB893499_gene388	1.374e-44	164.0	COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,47JHU@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_14564_0	326427.Cagg_3647	1.774e-14	80.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi,375VV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_14564_1	1304284.L21TH_1983	0.0002278	55.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TniQ
CMS3_k127_1461226_0	1254432.SCE1572_13250	5.806e-145	482.0	COG0001@1|root,COG0604@1|root,COG1020@1|root,COG3321@1|root,COG0001@2|Bacteria,COG0604@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,43E1T@68525|delta/epsilon subdivisions,2X7HJ@28221|Deltaproteobacteria,2Z3M9@29|Myxococcales	28221|Deltaproteobacteria	Q	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_1461226_1	1121377.KB906400_gene1221	1.773e-66	235.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111,NTP_transf_2
CMS3_k127_1461226_2	304371.MCP_0795	1.969e-42	160.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
CMS3_k127_1468952_1	660470.Theba_2370	6.501e-81	282.0	COG0077@1|root,COG0077@2|Bacteria,2GD6K@200918|Thermotogae	200918|Thermotogae	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS3_k127_1468952_9	926550.CLDAP_03240	3.612e-37	163.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	-
CMS3_k127_1468952_13	926550.CLDAP_01930	7.174e-14	86.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS3_k127_1468952_3	1405.DJ92_414	2.143e-74	262.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	yhgE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07471,ko:K13652,ko:K19056	-	-	-	-	ko00000,ko03000	-	-	-	DUF4153,DinB_2,GyrI-like,HTH_18
CMS3_k127_1468952_10	1385514.N782_11565	1.058e-27	119.0	COG3832@1|root,COG3832@2|Bacteria,1VDCF@1239|Firmicutes,4HM0C@91061|Bacilli,2YAMX@289201|Pontibacillus	91061|Bacilli	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_1468952_0	383372.Rcas_2663	2.973e-81	295.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
CMS3_k127_1468952_11	189753.AXAS01000009_gene6401	4.689e-21	100.0	COG0454@1|root,COG0456@2|Bacteria,1QU9D@1224|Proteobacteria,2TWZF@28211|Alphaproteobacteria,3JYDP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_1468952_8	382464.ABSI01000013_gene1910	8.039e-50	182.0	COG1670@1|root,COG1670@2|Bacteria,46X7U@74201|Verrucomicrobia,2IUXM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_1468952_4	211165.AJLN01000116_gene3408	2.974e-67	237.0	COG0500@1|root,COG0500@2|Bacteria,1GC3W@1117|Cyanobacteria,1JKSF@1189|Stigonemataceae	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_1468952_6	404589.Anae109_4238	4.849e-54	193.0	COG2030@1|root,COG2030@2|Bacteria,1RJN8@1224|Proteobacteria	1224|Proteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_1468952_5	926569.ANT_23660	4.244e-62	226.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS3_k127_1468952_7	485913.Krac_12227	3.652e-50	207.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_1468952_2	926560.KE387023_gene3263	2.218e-77	296.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_1468952_12	497964.CfE428DRAFT_0631	1.232e-20	95.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_1473593_0	552811.Dehly_1516	6.917e-94	338.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi	200795|Chloroflexi	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_1475887_0	522306.CAP2UW1_3681	2.91e-60	233.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K20951,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,Beta_helix,CARDB,DUF4465,F5_F8_type_C,Laminin_G_3,Peptidase_C2
CMS3_k127_1483354_2	326427.Cagg_2931	1.777e-58	227.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
CMS3_k127_1483354_1	266117.Rxyl_2616	9.085e-91	304.0	COG0346@1|root,COG1028@1|root,COG0346@2|Bacteria,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4CSAC@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1483354_0	1121377.KB906405_gene135	6.851e-140	454.0	COG0809@1|root,COG0809@2|Bacteria,1WJW8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS3_k127_1483354_4	479434.Sthe_2099	1.879e-43	171.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS3_k127_1483354_3	401053.AciPR4_2317	1.112e-50	201.0	COG2132@1|root,COG2132@2|Bacteria,3Y65V@57723|Acidobacteria,2JMCT@204432|Acidobacteriia	204432|Acidobacteriia	Q	PFAM multicopper oxidase type 2	-	-	1.16.3.3	ko:K06324	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_1484498_0	323261.Noc_1878	1.886e-23	115.0	COG2885@1|root,COG3409@1|root,COG2885@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K03286,ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,1.B.6,3.A.1.109.4	-	-	Amidase_2,OEP,OmpA,PG_binding_1
CMS3_k127_149057_2	926569.ANT_27050	1.693e-70	243.0	COG1695@1|root,COG1695@2|Bacteria,2G9N5@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
CMS3_k127_149057_0	926569.ANT_27060	1.194e-103	343.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_149057_1	926569.ANT_27070	1.085e-80	275.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_1490787_1	1206732.BAGD01000280_gene6495	4.888e-20	95.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4G9ZH@85025|Nocardiaceae	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_1490787_0	1337093.MBE-LCI_3727	4.223e-121	398.0	COG0667@1|root,COG0667@2|Bacteria,1R3YU@1224|Proteobacteria,2VEU3@28211|Alphaproteobacteria,2PA45@245186|Loktanella	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_1499012_1	765914.ThisiDRAFT_0905	2.993e-16	89.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_1499012_0	237368.SCABRO_03049	2.304e-167	541.0	COG2192@1|root,COG2192@2|Bacteria,2IYCS@203682|Planctomycetes	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_1503645_6	56780.SYN_02637	3.757e-62	224.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2MR3X@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS3_k127_1503645_8	926550.CLDAP_15400	1.93e-53	198.0	COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi	200795|Chloroflexi	C	electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_1503645_5	765420.OSCT_0903	3.542e-64	247.0	COG1287@1|root,COG1287@2|Bacteria,2G8R6@200795|Chloroflexi,377ZY@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1503645_4	324602.Caur_1361	3.283e-78	264.0	COG2343@1|root,COG2343@2|Bacteria,2GARM@200795|Chloroflexi,3775Q@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS3_k127_1503645_14	926569.ANT_06210	4.707e-11	76.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
CMS3_k127_1503645_13	926550.CLDAP_34540	6.667e-12	78.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
CMS3_k127_1503645_7	765420.OSCT_1126	9.684e-56	205.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
CMS3_k127_1503645_0	1183438.GKIL_3722	4.16e-239	759.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_1503645_10	1121438.JNJA01000002_gene3714	1.813e-42	173.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_1503645_11	756499.Desde_2900	4.22e-28	120.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,26230@186807|Peptococcaceae	186801|Clostridia	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_1503645_12	309801.trd_0480	8.489e-15	83.0	COG1388@1|root,COG4990@1|root,COG1388@2|Bacteria,COG4990@2|Bacteria,2G95J@200795|Chloroflexi,27Y1K@189775|Thermomicrobia	189775|Thermomicrobia	M	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_C39_2
CMS3_k127_1503645_3	867845.KI911784_gene762	4.112e-84	292.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1503645_1	926550.CLDAP_04540	4.084e-126	419.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_1503645_2	926569.ANT_11190	3.386e-97	320.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS3_k127_1503645_9	765420.OSCT_2947	3.409e-48	181.0	COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi,374XV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1505608_0	401526.TcarDRAFT_0956	2.511e-110	369.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4H24I@909932|Negativicutes	909932|Negativicutes	S	MazG family	mazG	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
CMS3_k127_1505608_1	316274.Haur_0218	3.031e-78	265.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS3_k127_1511023_2	926550.CLDAP_13010	3.156e-24	121.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,TPR_12,Trans_reg_C
CMS3_k127_1511023_0	1121380.JNIW01000017_gene2949	8.726e-113	403.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
CMS3_k127_1511023_1	1040989.AWZU01000041_gene6031	6.034e-37	162.0	COG0457@1|root,COG0457@2|Bacteria,1QYGY@1224|Proteobacteria,2TZCN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1516252_0	1174528.JH992898_gene4471	1.76e-196	655.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,1GHDU@1117|Cyanobacteria,1JKFU@1189|Stigonemataceae	1117|Cyanobacteria	Q	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,HemolysinCabind,LTD
CMS3_k127_1516252_5	395961.Cyan7425_1432	3.749e-05	53.0	COG1413@1|root,COG1413@2|Bacteria,1G341@1117|Cyanobacteria,3KGXR@43988|Cyanothece	1117|Cyanobacteria	C	PFAM PBS lyase HEAT domain protein repeat-containing protein	nblB	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_1516252_4	316274.Haur_1710	7.962e-14	77.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K03407,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_1516252_2	502025.Hoch_3232	3.291e-44	182.0	COG3540@1|root,COG5083@1|root,COG3540@2|Bacteria,COG5083@2|Bacteria,1PI5U@1224|Proteobacteria,43DVA@68525|delta/epsilon subdivisions,2X8XW@28221|Deltaproteobacteria,2Z0Z1@29|Myxococcales	28221|Deltaproteobacteria	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
CMS3_k127_1516252_3	489825.LYNGBM3L_42690	1.005e-31	138.0	COG4424@1|root,COG4424@2|Bacteria,1G9Y1@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_1516252_1	95619.PM1_0218900	1.302e-81	280.0	COG0596@1|root,COG0596@2|Bacteria,1RDP1@1224|Proteobacteria,1S67D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_1517676_1	479434.Sthe_1490	1.199e-38	152.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_1517676_0	187272.Mlg_0221	2.413e-98	332.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,1T2QT@1236|Gammaproteobacteria,1WWCJ@135613|Chromatiales	135613|Chromatiales	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS3_k127_1533607_0	266117.Rxyl_0536	1.386e-164	532.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria	201174|Actinobacteria	G	D-galactarate dehydratase Altronate	-	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
CMS3_k127_1533621_0	1123023.JIAI01000012_gene9140	1.271e-71	257.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria,4EAV1@85010|Pseudonocardiales	201174|Actinobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_1533621_1	1382356.JQMP01000003_gene2593	3.152e-10	63.0	2C7F0@1|root,2Z832@2|Bacteria,2G715@200795|Chloroflexi,27YDA@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM HAS barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_153427_0	391037.Sare_0718	2.547e-202	645.0	COG1020@1|root,COG1020@2|Bacteria,2I9QX@201174|Actinobacteria,4DCJ9@85008|Micromonosporales	201174|Actinobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_153427_1	749414.SBI_01672	2.903e-175	560.0	COG1018@1|root,COG1018@2|Bacteria,2GJ1N@201174|Actinobacteria	201174|Actinobacteria	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_153427_2	1500257.JQNM01000022_gene2686	3.692e-108	355.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,4BAKZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_1537031_1	1121380.JNIW01000034_gene3761	7.343e-60	214.0	2DK45@1|root,308DR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
CMS3_k127_1537031_2	485913.Krac_2032	5.636e-51	187.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_18,AAA_33,Zeta_toxin
CMS3_k127_1537031_0	357808.RoseRS_2964	5.215e-235	736.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2G7MP@200795|Chloroflexi,3760K@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS3_k127_1543013_3	1397527.Q670_12490	5.56e-15	84.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1XIVQ@135619|Oceanospirillales	135619|Oceanospirillales	C	Aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_1543013_0	981384.AEYW01000006_gene2477	7.711e-61	219.0	COG4544@1|root,COG4544@2|Bacteria,1MY56@1224|Proteobacteria,2U9GK@28211|Alphaproteobacteria,4NBUA@97050|Ruegeria	28211|Alphaproteobacteria	S	SOS response	-	-	-	ko:K14160	-	-	-	-	ko00000,ko03400	-	-	-	-
CMS3_k127_1543013_1	1123501.KB902310_gene63	4.759e-51	185.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG1247 Sortase and related acyltransferases	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS3_k127_1543013_2	644107.SL1157_0069	7.793e-22	97.0	COG1076@1|root,COG1076@2|Bacteria,1N270@1224|Proteobacteria,2TTX1@28211|Alphaproteobacteria,4NBWR@97050|Ruegeria	28211|Alphaproteobacteria	O	DnaJ molecular chaperone homology domain	djlA	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
CMS3_k127_1545825_1	1198114.AciX9_1910	9.088e-40	150.0	COG0019@1|root,COG0019@2|Bacteria,3Y2W4@57723|Acidobacteria,2JI3I@204432|Acidobacteriia	204432|Acidobacteriia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS3_k127_1545825_0	1541065.JRFE01000014_gene1505	6.955e-237	799.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG5276@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1G8F1@1117|Cyanobacteria,3VMVS@52604|Pleurocapsales	1117|Cyanobacteria	M	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
CMS3_k127_155496_2	744872.Spica_2539	5.907e-43	176.0	COG4166@1|root,COG4166@2|Bacteria,2J687@203691|Spirochaetes	203691|Spirochaetes	E	extracellular solute-binding protein, family 5	oppA-1	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_155496_0	1380390.JIAT01000010_gene4392	1.475e-197	649.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
CMS3_k127_155496_3	1521187.JPIM01000052_gene3533	4.65e-23	106.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
CMS3_k127_155496_1	926550.CLDAP_18870	1.718e-79	282.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_1560299_1	926550.CLDAP_32460	9.889e-05	48.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1560299_0	926569.ANT_23120	1.279e-71	253.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS3_k127_1560440_1	391625.PPSIR1_08202	7.626e-40	159.0	KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_1560440_2	926550.CLDAP_11150	1.003e-27	119.0	2DRW3@1|root,33DCW@2|Bacteria,2G7E0@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF1992)	-	-	-	ko:K19373	-	-	-	-	ko00000,ko03110	-	-	-	DUF1992
CMS3_k127_1560440_0	272134.KB731324_gene1482	9.902e-47	177.0	COG0730@1|root,COG0730@2|Bacteria,1G76Y@1117|Cyanobacteria	1117|Cyanobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_1566003_4	290317.Cpha266_0842	5.832e-81	279.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1566003_8	1120950.KB892756_gene6670	6.854e-22	108.0	COG3055@1|root,COG3055@2|Bacteria,2HC50@201174|Actinobacteria	201174|Actinobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
CMS3_k127_1566003_0	639030.JHVA01000001_gene1853	2.599e-210	659.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS3_k127_1566003_7	479434.Sthe_2959	8.321e-40	152.0	COG1977@1|root,COG1977@2|Bacteria,2G6VH@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1566003_5	1173264.KI913951_gene4625	5.22e-49	179.0	COG2764@1|root,COG2764@2|Bacteria,1G8SR@1117|Cyanobacteria	1117|Cyanobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS3_k127_1566003_3	118168.MC7420_7177	9.238e-135	439.0	COG2425@1|root,COG2425@2|Bacteria,1G2M9@1117|Cyanobacteria,1H9MM@1150|Oscillatoriales	1117|Cyanobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
CMS3_k127_1566003_1	102129.Lepto7375DRAFT_5778	1.046e-202	656.0	COG1916@1|root,COG1916@2|Bacteria,1G4FN@1117|Cyanobacteria,1H89R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1566003_2	1469607.KK073769_gene5196	7.122e-172	545.0	COG0714@1|root,COG0714@2|Bacteria,1G37K@1117|Cyanobacteria,1HQG1@1161|Nostocales	1117|Cyanobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS3_k127_1566003_6	105422.BBPM01000018_gene2429	1.166e-47	188.0	COG5094@1|root,COG5094@2|Bacteria,2I306@201174|Actinobacteria,2NFE3@228398|Streptacidiphilus	201174|Actinobacteria	K	RNA polymerase II transcriptional preinitiation complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1569118_0	1128421.JAGA01000002_gene397	3.861e-155	505.0	COG0172@1|root,COG0172@2|Bacteria,2NNRH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528,iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
CMS3_k127_1569118_2	926560.KE387023_gene2816	2.264e-65	240.0	COG2010@1|root,COG2010@2|Bacteria,1WM84@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
CMS3_k127_1569118_1	926550.CLDAP_38400	6.685e-152	491.0	COG0297@1|root,COG0297@2|Bacteria,2GA6I@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase Family 4	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1569118_3	926550.CLDAP_37610	3.747e-64	231.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_1570267_6	357808.RoseRS_4105	2.992e-44	164.0	COG0411@1|root,COG0411@2|Bacteria,2GABI@200795|Chloroflexi,376AR@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_1570267_2	324602.Caur_3636	2.794e-95	317.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374V9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS3_k127_1570267_5	1128421.JAGA01000001_gene2258	2.258e-78	274.0	COG0559@1|root,COG0559@2|Bacteria	2|Bacteria	E	leucine import across plasma membrane	MA20_23490	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_1570267_4	867845.KI911784_gene2998	1.454e-79	281.0	COG4177@1|root,COG4177@2|Bacteria,2G8ZK@200795|Chloroflexi,375J2@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_1570267_3	316274.Haur_3799	4.632e-91	310.0	COG0332@1|root,COG0332@2|Bacteria,2G7TB@200795|Chloroflexi	200795|Chloroflexi	H	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_1570267_1	485913.Krac_12015	3.16e-142	463.0	COG0183@1|root,COG0183@2|Bacteria,2G66E@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_1570267_0	518766.Rmar_1548	1.13e-224	716.0	COG1086@1|root,COG1086@2|Bacteria	2|Bacteria	GM	Polysaccharide biosynthesis protein	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD
CMS3_k127_1573975_0	926569.ANT_10850	5.158e-53	202.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636,ko:K07642	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
CMS3_k127_1573975_2	1122918.KB907257_gene2763	3.516e-13	76.0	COG2050@1|root,COG2050@2|Bacteria,1V6F1@1239|Firmicutes,4IR17@91061|Bacilli,276KX@186822|Paenibacillaceae	91061|Bacilli	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1573975_1	316274.Haur_0685	3.713e-36	140.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS3_k127_1583159_1	1121377.KB906400_gene1221	1.14e-44	168.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111,NTP_transf_2
CMS3_k127_1583159_2	1122176.KB903565_gene3366	1.391e-36	145.0	COG4430@1|root,COG4430@2|Bacteria,4NWI7@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
CMS3_k127_1583159_0	1298880.AUEV01000007_gene4556	3.743e-75	262.0	COG3570@1|root,COG3570@2|Bacteria,2GNSH@201174|Actinobacteria	201174|Actinobacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
CMS3_k127_1583159_3	1384054.N790_02155	1.024e-19	92.0	COG1670@1|root,COG1670@2|Bacteria,1N18Y@1224|Proteobacteria,1S8ZQ@1236|Gammaproteobacteria,1X6VH@135614|Xanthomonadales	135614|Xanthomonadales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_1587994_0	644966.Tmar_0084	2.911e-81	279.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WD1R@538999|Clostridiales incertae sedis	186801|Clostridia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS3_k127_1587994_1	1348657.M622_02945	4.871e-56	200.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,2VQZE@28216|Betaproteobacteria,2KW2S@206389|Rhodocyclales	206389|Rhodocyclales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1592639_0	1403819.BATR01000042_gene1249	1.083e-24	112.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS3_k127_1597479_2	485913.Krac_10280	1.098e-40	154.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi	2|Bacteria	S	PFAM alpha beta hydrolase fold	MA20_20400	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_1597479_0	1121019.AUMN01000009_gene1952	1.28e-119	393.0	COG1680@1|root,COG1680@2|Bacteria,2GIX5@201174|Actinobacteria,1WA51@1268|Micrococcaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1597479_3	1313421.JHBV01000006_gene351	1.693e-19	103.0	COG3023@1|root,COG3023@2|Bacteria,4NRQX@976|Bacteroidetes	976|Bacteroidetes	V	Psort location Cytoplasmic, score 8.96	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
CMS3_k127_1597479_1	926550.CLDAP_08400	1.145e-54	213.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	2|Bacteria	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12
CMS3_k127_1609116_6	1089551.KE386572_gene2138	1.248e-07	61.0	COG0392@1|root,COG0392@2|Bacteria,1PT39@1224|Proteobacteria,2V51S@28211|Alphaproteobacteria,4BT2C@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS3_k127_1609116_2	926569.ANT_25930	2.759e-24	118.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,VanY,YkuD
CMS3_k127_1609116_4	1382306.JNIM01000001_gene2486	1.016e-10	71.0	2EDBT@1|root,33781@2|Bacteria,2G8Y5@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1609116_1	926550.CLDAP_21530	2.168e-143	466.0	COG0665@1|root,COG0665@2|Bacteria,2G7VQ@200795|Chloroflexi	200795|Chloroflexi	E	PFAM FAD dependent oxidoreductase	-	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
CMS3_k127_1609116_0	926569.ANT_23280	4.637e-175	560.0	COG0520@1|root,COG0520@2|Bacteria,2G85X@200795|Chloroflexi	200795|Chloroflexi	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_1609116_5	696747.NIES39_C02780	5.007e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HA36@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_12,TPR_7,TPR_8
CMS3_k127_1609116_3	1121377.KB906434_gene695	3.735e-17	94.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS3_k127_1618222_1	109871.XP_006679391.1	8.683e-69	239.0	COG0138@1|root,KOG2555@2759|Eukaryota,38H8U@33154|Opisthokonta,3NY4C@4751|Fungi	4751|Fungi	F	bifunctional purine biosynthesis protein	ADE17	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0003937,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009060,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009653,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019637,GO:0019693,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0032502,GO:0032505,GO:0034293,GO:0034641,GO:0034654,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045333,GO:0046040,GO:0046390,GO:0046483,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903046	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS3_k127_1618222_2	926550.CLDAP_15680	1.274e-57	209.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS3_k127_1618222_4	243231.GSU0022	4.795e-06	54.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_1618222_0	1121396.KB893051_gene3457	1.021e-92	314.0	COG2267@1|root,COG2267@2|Bacteria,1QVW4@1224|Proteobacteria,42T0R@68525|delta/epsilon subdivisions,2WPP3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_1618222_3	935840.JAEQ01000009_gene1333	2.147e-29	131.0	COG3799@1|root,COG3799@2|Bacteria,1MW90@1224|Proteobacteria,2TU5V@28211|Alphaproteobacteria,43NBG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Methylaspartate ammonia-lyase C-terminus	-	-	4.3.1.2	ko:K04835	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R03696	RC00979	ko00000,ko00001,ko00002,ko01000	-	-	-	MAAL_C,MAAL_N
CMS3_k127_1619458_6	926569.ANT_06250	1.04e-32	134.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
CMS3_k127_1619458_7	1521187.JPIM01000060_gene2922	7.376e-07	54.0	2EI16@1|root,33BSP@2|Bacteria,2G9M5@200795|Chloroflexi,3761S@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1619458_0	926569.ANT_02040	2.199e-177	571.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_1619458_1	1206744.BAGL01000033_gene220	3.143e-114	376.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4FZB8@85025|Nocardiaceae	201174|Actinobacteria	I	Coenzyme A transferase	catI	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS3_k127_1619458_3	926569.ANT_02010	4.756e-90	306.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS3_k127_1619458_2	1279015.KB908458_gene2565	1.524e-90	302.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1Y3SW@135624|Aeromonadales	135624|Aeromonadales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS3_k127_1619458_5	502025.Hoch_2745	5.539e-80	278.0	28NPB@1|root,2ZBP9@2|Bacteria,1R3HY@1224|Proteobacteria,43BB6@68525|delta/epsilon subdivisions,2X6QB@28221|Deltaproteobacteria,2YYYB@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_1619458_4	525904.Tter_2279	3.832e-80	279.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
CMS3_k127_1622821_0	1121468.AUBR01000017_gene2394	1.042e-131	450.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_1622821_1	1499967.BAYZ01000172_gene5780	4.194e-66	232.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	galE3	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_1629290_0	926569.ANT_11390	9.76e-51	184.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_1629290_1	926550.CLDAP_29040	1.173e-37	146.0	COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi	200795|Chloroflexi	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS3_k127_1629557_0	926550.CLDAP_30470	0.0	1605.0	COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1629557_9	1122605.KB893637_gene3429	7.686e-42	159.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1IS2D@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_1629557_7	760192.Halhy_1961	1.276e-45	168.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,1IS9I@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_1629557_10	926550.CLDAP_30460	1.683e-29	130.0	COG3381@1|root,COG3381@2|Bacteria,2G96P@200795|Chloroflexi	200795|Chloroflexi	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
CMS3_k127_1629557_6	247633.GP2143_15511	4.326e-46	169.0	COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,1S62S@1236|Gammaproteobacteria,1J6EQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_1629557_11	1128421.JAGA01000001_gene2168	3.596e-20	94.0	COG2005@1|root,COG2005@2|Bacteria,2NRCV@2323|unclassified Bacteria	2|Bacteria	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1,PBP_like_2
CMS3_k127_1629557_2	479434.Sthe_3395	3.229e-97	325.0	COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi,27Z56@189775|Thermomicrobia	189775|Thermomicrobia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
CMS3_k127_1629557_5	457570.Nther_0328	3.466e-60	218.0	COG4662@1|root,COG4662@2|Bacteria,1TRK7@1239|Firmicutes,249VG@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
CMS3_k127_1629557_4	926569.ANT_30990	1.183e-62	229.0	COG1117@1|root,COG1117@2|Bacteria	2|Bacteria	P	ATPase-coupled phosphate ion transmembrane transporter activity	pstB	-	3.6.3.27,3.6.3.55	ko:K02036,ko:K06857	ko02010,map02010	M00186,M00222	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.7	-	-	ABC_tran
CMS3_k127_1629557_8	391625.PPSIR1_24114	1.806e-42	161.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,42SKW@68525|delta/epsilon subdivisions,2WRVI@28221|Deltaproteobacteria,2YY5Q@29|Myxococcales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	4.2.1.103	ko:K18199	ko00930,map00930	-	R05771	RC01467	ko00000,ko00001,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS3_k127_1629557_3	383372.Rcas_0364	2.28e-63	223.0	COG4665@1|root,COG4665@2|Bacteria,2G8FW@200795|Chloroflexi,377BR@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS3_k127_1629557_1	926550.CLDAP_06650	1.099e-187	596.0	COG4664@1|root,COG4664@2|Bacteria,2G81X@200795|Chloroflexi	200795|Chloroflexi	Q	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS3_k127_1635833_2	383372.Rcas_3343	1.718e-127	414.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,376B1@32061|Chloroflexia	32061|Chloroflexia	I	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS3_k127_1635833_7	525904.Tter_1495	1.391e-44	179.0	COG0642@1|root,COG2205@2|Bacteria,2NQZ3@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_1635833_3	485913.Krac_5262	2.585e-64	229.0	COG1296@1|root,COG1296@2|Bacteria,2G6SG@200795|Chloroflexi	200795|Chloroflexi	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
CMS3_k127_1635833_11	485913.Krac_5263	5.558e-23	111.0	COG4392@1|root,COG4392@2|Bacteria,2G7HT@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
CMS3_k127_1635833_12	1150599.MPHLEI_04445	1.348e-09	69.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,233QA@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1635833_1	525897.Dbac_0439	6.108e-141	462.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,43ADQ@68525|delta/epsilon subdivisions,2X5TK@28221|Deltaproteobacteria,2MAD4@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
CMS3_k127_1635833_4	765420.OSCT_1844	2.319e-60	219.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
CMS3_k127_1635833_8	1234664.AMRO01000003_gene684	7.945e-44	167.0	COG0454@1|root,COG0456@2|Bacteria,1VC1N@1239|Firmicutes,4HJT0@91061|Bacilli,1WGJE@129337|Geobacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS3_k127_1635833_10	525263.HMPREF0298_0949	3.078e-38	149.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria,22NSG@1653|Corynebacteriaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS3_k127_1635833_14	35754.JNYJ01000008_gene3173	0.0004973	50.0	COG3866@1|root,COG4733@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria,2GNKW@201174|Actinobacteria,4D9AI@85008|Micromonosporales	201174|Actinobacteria	G	Amb_all	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase_C
CMS3_k127_1635833_9	926561.KB900618_gene434	1.946e-42	166.0	COG1878@1|root,COG1878@2|Bacteria,1TSXB@1239|Firmicutes,24B80@186801|Clostridia,3WB46@53433|Halanaerobiales	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS3_k127_1635833_6	1356852.N008_17330	5.929e-47	179.0	COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,47Q9R@768503|Cytophagia	976|Bacteroidetes	M	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS3_k127_1635833_0	439235.Dalk_4758	7.25e-168	542.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,430TE@68525|delta/epsilon subdivisions,2WVZR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS3_k127_1635833_13	1144275.COCOR_07974	3.999e-06	59.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
CMS3_k127_1635833_5	926569.ANT_04230	1.567e-48	179.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_1642687_4	1298880.AUEV01000017_gene1002	3.743e-09	64.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_1642687_2	1173022.Cri9333_4294	1.476e-42	171.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HA4H@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS3_k127_1642687_3	1385517.N800_04555	5.538e-13	75.0	2DRDY@1|root,33BC0@2|Bacteria	2|Bacteria	S	PFAM Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
CMS3_k127_1642687_0	926569.ANT_15780	2.101e-261	814.0	COG1032@1|root,COG1032@2|Bacteria,2G5SI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_1642687_1	926550.CLDAP_36260	5.364e-127	417.0	COG0463@1|root,COG0463@2|Bacteria,2G7KQ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1648095_1	926569.ANT_18470	5.978e-45	173.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
CMS3_k127_1648095_2	1294265.JCM21738_1283	3.443e-34	140.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1648095_0	357808.RoseRS_4203	2.155e-54	205.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi,375GW@32061|Chloroflexia	32061|Chloroflexia	O	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS3_k127_1651549_7	765420.OSCT_2786	1.343e-08	66.0	COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi,375TM@32061|Chloroflexia	32061|Chloroflexia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS3_k127_1651549_0	867903.ThesuDRAFT_00685	1.799e-136	444.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_1651549_2	926569.ANT_23420	2.526e-91	310.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS3_k127_1651549_1	926569.ANT_23400	3.294e-117	394.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_1651549_4	926569.ANT_23380	1.129e-82	289.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS3_k127_1651549_3	1382306.JNIM01000001_gene36	1.804e-84	295.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS3_k127_1651549_5	644966.Tmar_0354	9.107e-41	156.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WCSY@538999|Clostridiales incertae sedis	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
CMS3_k127_1653033_3	1382356.JQMP01000003_gene1909	3.012e-65	233.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS3_k127_1653033_0	926550.CLDAP_32500	2.042e-137	448.0	COG0026@1|root,COG0026@2|Bacteria,2G7GU@200795|Chloroflexi	200795|Chloroflexi	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1653033_6	525246.HMPREF0058_2228	2.549e-07	64.0	COG0739@1|root,COG0739@2|Bacteria,2GM7Q@201174|Actinobacteria,4D81C@85005|Actinomycetales	201174|Actinobacteria	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_1653033_1	926550.CLDAP_09570	5.569e-107	381.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2G86V@200795|Chloroflexi	200795|Chloroflexi	KLT	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS3_k127_1653033_2	926550.CLDAP_09580	1.603e-72	256.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi	200795|Chloroflexi	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
CMS3_k127_1653033_7	743720.Psefu_4052	6.207e-07	59.0	COG0454@1|root,COG0456@2|Bacteria,1RCTN@1224|Proteobacteria,1SRRN@1236|Gammaproteobacteria,1YZB6@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS3_k127_1653033_4	1370125.AUWT01000022_gene4434	3.873e-41	156.0	COG0596@1|root,COG0596@2|Bacteria,2GKJB@201174|Actinobacteria,23F6M@1762|Mycobacteriaceae	201174|Actinobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhmA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_1661650_0	1385512.N784_14300	3.671e-16	90.0	COG1196@1|root,COG1196@2|Bacteria,1UIE6@1239|Firmicutes,4IT31@91061|Bacilli,2YAFZ@289201|Pontibacillus	91061|Bacilli	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS3_k127_1661650_1	926550.CLDAP_32470	2.366e-12	74.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1668607_7	366394.Smed_2912	1.819e-29	126.0	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,2TQN0@28211|Alphaproteobacteria,4B78I@82115|Rhizobiaceae	28211|Alphaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	MA20_35620	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_1668607_1	926550.CLDAP_22740	3.787e-164	524.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS3_k127_1668607_2	926569.ANT_13330	1.184e-114	378.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1668607_6	926550.CLDAP_23360	7.728e-55	205.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_1668607_3	926569.ANT_08200	2.629e-89	301.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS3_k127_1668607_4	1123257.AUFV01000001_gene1577	1.427e-79	274.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria,1X6B4@135614|Xanthomonadales	135614|Xanthomonadales	S	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_1668607_0	313624.NSP_2760	3.642e-182	586.0	COG1132@1|root,COG1132@2|Bacteria,1G1QS@1117|Cyanobacteria,1HS1R@1161|Nostocales	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1668607_5	1007103.AFHW01000145_gene4105	1.621e-71	257.0	COG1132@1|root,COG1132@2|Bacteria,1UZA0@1239|Firmicutes,4HC2E@91061|Bacilli,26VPZ@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS3_k127_1668705_3	1128421.JAGA01000004_gene2544	1.032e-55	197.0	COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS3_k127_1668705_13	1122182.KB903823_gene1382	8.113e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2IK0G@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1668705_1	1128421.JAGA01000003_gene3426	5.312e-67	238.0	COG0489@1|root,COG0489@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	2.7.10.2	ko:K08253,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
CMS3_k127_1668705_9	697303.Thewi_0861	5.285e-18	92.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,42HYM@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
CMS3_k127_1668705_6	926550.CLDAP_39150	8.731e-41	160.0	COG3944@1|root,COG3944@2|Bacteria,2G7A7@200795|Chloroflexi	200795|Chloroflexi	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
CMS3_k127_1668705_0	926550.CLDAP_39140	8.831e-121	399.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1668705_12	671143.DAMO_0301	1.17e-06	61.0	COG0457@1|root,COG4745@1|root,COG0457@2|Bacteria,COG4745@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2,TPR_2,TPR_8
CMS3_k127_1668705_10	1343739.PAP_05575	2.747e-12	70.0	COG1983@1|root,arCOG03456@2157|Archaea,2XZT2@28890|Euryarchaeota,244RW@183968|Thermococci	183968|Thermococci	K	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
CMS3_k127_1668705_8	768671.ThimaDRAFT_1522	5.104e-24	108.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1668705_5	357808.RoseRS_3251	8.888e-48	181.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi,375I2@32061|Chloroflexia	32061|Chloroflexia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS3_k127_1668705_11	394221.Mmar10_0053	1.151e-10	65.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,43YEB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	YGGT family	MA20_25225	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CMS3_k127_1668705_2	1303518.CCALI_01951	6.016e-57	206.0	COG0177@1|root,COG0177@2|Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS3_k127_1668705_7	937777.Deipe_1715	1.353e-38	151.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1668705_4	446470.Snas_2763	3.475e-52	195.0	COG0702@1|root,COG0702@2|Bacteria,2HC75@201174|Actinobacteria,4F04P@85014|Glycomycetales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS3_k127_1668726_0	1297742.A176_01988	8.585e-47	187.0	COG0330@1|root,COG0330@2|Bacteria,1Q1RS@1224|Proteobacteria,437F1@68525|delta/epsilon subdivisions,2X2MG@28221|Deltaproteobacteria,2YTT6@29|Myxococcales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_1668726_1	512565.AMIS_4910	6.878e-11	75.0	COG4126@1|root,COG4126@2|Bacteria,2IFSR@201174|Actinobacteria,4DFDC@85008|Micromonosporales	201174|Actinobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
CMS3_k127_1683328_2	926569.ANT_29790	1.032e-13	72.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS3_k127_1683328_3	1120950.KB892830_gene5043	6.693e-07	60.0	COG0454@1|root,COG0456@2|Bacteria,2INZ5@201174|Actinobacteria,4DVQY@85009|Propionibacteriales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_1683328_0	1128421.JAGA01000002_gene1518	4.336e-107	353.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CMS3_k127_1683328_1	1123257.AUFV01000016_gene3479	1.846e-44	177.0	COG2010@1|root,COG2010@2|Bacteria,1MXXQ@1224|Proteobacteria,1SPE3@1236|Gammaproteobacteria,1X6TH@135614|Xanthomonadales	135614|Xanthomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_168840_0	118173.KB235914_gene2214	0.0	1814.0	COG3209@1|root,COG3209@2|Bacteria,1GCJW@1117|Cyanobacteria,1HE9Y@1150|Oscillatoriales	1117|Cyanobacteria	M	Insecticide toxin TcdB middle/N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
CMS3_k127_168840_1	926550.CLDAP_19470	1.337e-67	241.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_1697006_0	383372.Rcas_3594	4.311e-200	638.0	COG0028@1|root,COG0028@2|Bacteria,2G7NZ@200795|Chloroflexi	200795|Chloroflexi	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_1702368_6	1304874.JAFY01000002_gene410	1.487e-25	116.0	COG0561@1|root,COG0561@2|Bacteria,3TB3P@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS3_k127_1702368_7	469383.Cwoe_0549	3.696e-10	65.0	COG2197@1|root,COG2197@2|Bacteria,2GN3A@201174|Actinobacteria,4CREU@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_1702368_1	926550.CLDAP_21020	5.564e-72	249.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_1702368_3	926550.CLDAP_21010	3.107e-61	228.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_1702368_5	931626.Awo_c14850	1.118e-50	190.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25VEF@186806|Eubacteriaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_1702368_2	1123504.JQKD01000027_gene4123	8.208e-66	239.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria,4ABW8@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	PFAM peptidase S58 DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
CMS3_k127_1702368_0	1163617.SCD_n02853	7.422e-155	498.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS3_k127_1702368_4	521011.Mpal_1783	1.895e-55	209.0	COG3291@1|root,arCOG02559@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,NosD,PKD,SBBP
CMS3_k127_1704930_2	268407.PWYN_22775	7.533e-73	250.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26TF8@186822|Paenibacillaceae	91061|Bacilli	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
CMS3_k127_1704930_3	87626.PTD2_04761	9.275e-10	64.0	arCOG06733@1|root,313GU@2|Bacteria,1RKN4@1224|Proteobacteria,1S7UT@1236|Gammaproteobacteria,2Q3TT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1704930_0	1121272.KB903249_gene2239	7.799e-101	338.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DB8J@85008|Micromonosporales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
CMS3_k127_1704930_1	497964.CfE428DRAFT_0631	8.138e-91	323.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_1706417_1	479434.Sthe_1183	3.006e-86	298.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_1706417_3	926569.ANT_20710	4.544e-32	134.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
CMS3_k127_1706417_0	56107.Cylst_3852	1.098e-88	302.0	COG4221@1|root,COG4221@2|Bacteria,1GHFE@1117|Cyanobacteria,1HTPE@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1706417_2	926569.ANT_23030	1.25e-33	144.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS3_k127_1706417_4	316274.Haur_2224	2.667e-14	84.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VanZ
CMS3_k127_1706417_5	1367847.JCM7686_0703	1.202e-05	57.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2PUVF@265|Paracoccus	28211|Alphaproteobacteria	M	Peptidase family M23	MA20_30780	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_1706615_1	420246.GTNG_1330	1.062e-98	325.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4HB5P@91061|Bacilli,1WE83@129337|Geobacillus	91061|Bacilli	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_1706615_2	525904.Tter_0396	5.703e-77	270.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_1706615_0	1536772.R70723_09730	5.298e-124	404.0	COG3458@1|root,COG3458@2|Bacteria,1TS02@1239|Firmicutes,4HDID@91061|Bacilli,26QEJ@186822|Paenibacillaceae	91061|Bacilli	Q	Acetyl esterase	cah	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
CMS3_k127_1708457_0	311402.Avi_5349	3.959e-217	691.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria,4B73U@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	dppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_1708457_1	383372.Rcas_0007	4.577e-164	534.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi,376BY@32061|Chloroflexia	32061|Chloroflexia	L	Helix-hairpin-helix DNA-binding, class 1	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
CMS3_k127_1708457_2	1370121.AUWS01000020_gene6620	1.041e-19	96.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,236D8@1762|Mycobacteriaceae	201174|Actinobacteria	T	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_1722446_0	670487.Ocepr_0494	1.541e-40	163.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
CMS3_k127_1723595_3	1254432.SCE1572_39530	1.377e-08	61.0	COG3173@1|root,COG3173@2|Bacteria,1R5VZ@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
CMS3_k127_1723595_1	309800.C498_09586	3.17e-177	582.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
CMS3_k127_1723595_2	926550.CLDAP_25240	8.242e-24	113.0	COG1547@1|root,COG3437@1|root,COG1547@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309,HD
CMS3_k127_1723595_0	211165.AJLN01000042_gene530	8.48e-305	960.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1JKQM@1189|Stigonemataceae	1117|Cyanobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS3_k127_1733669_0	357808.RoseRS_0010	4.443e-92	315.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_1733669_1	765420.OSCT_1750	3.388e-23	112.0	COG1807@1|root,COG1807@2|Bacteria,2GAPY@200795|Chloroflexi,376ZD@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1733963_1	926569.ANT_30520	4.061e-98	337.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_N,Big_5,Malt_amylase_C
CMS3_k127_1733963_4	1157708.KB907472_gene1301	1.163e-05	56.0	COG3103@1|root,COG4991@2|Bacteria,1N1ZX@1224|Proteobacteria,2VSMT@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4
CMS3_k127_1733963_0	926550.CLDAP_24240	0.0	1005.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
CMS3_k127_1733963_2	221109.22776282	2.574e-33	143.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,23J3F@182709|Oceanobacillus	91061|Bacilli	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_1733963_3	869210.Marky_0061	3.071e-20	91.0	COG3638@1|root,COG3638@2|Bacteria,1WIEK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
CMS3_k127_1750002_0	926569.ANT_15490	6.045e-280	873.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_1750002_1	1304874.JAFY01000007_gene2490	2.642e-70	260.0	COG4251@1|root,COG4936@1|root,COG4251@2|Bacteria,COG4936@2|Bacteria,3TCMP@508458|Synergistetes	2|Bacteria	T	GHKL domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HD,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR
CMS3_k127_1758052_0	317936.Nos7107_1832	1.11e-61	223.0	COG3393@1|root,COG3393@2|Bacteria,1G551@1117|Cyanobacteria,1HKPV@1161|Nostocales	1117|Cyanobacteria	S	PFAM Acetyltransferase (GNAT) family	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,FR47
CMS3_k127_1758052_1	1297742.A176_05653	5.502e-11	68.0	2DSU6@1|root,33HF2@2|Bacteria,1R3KD@1224|Proteobacteria,43DKN@68525|delta/epsilon subdivisions,2X8RU@28221|Deltaproteobacteria,2YW3M@29|Myxococcales	28221|Deltaproteobacteria	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1767650_0	1121382.JQKG01000005_gene3364	2.164e-154	493.0	COG4992@1|root,COG4992@2|Bacteria,1WIII@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.13,2.6.1.82	ko:K00819,ko:K09251	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667,R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_1767650_2	640511.BC1002_1278	8.071e-65	243.0	COG1262@1|root,COG2319@1|root,COG1262@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria,1K773@119060|Burkholderiaceae	28216|Betaproteobacteria	S	WD40 repeats	-	-	-	ko:K20332	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	NACHT,Pentapeptide,TIR_2,WD40
CMS3_k127_1767650_3	1128421.JAGA01000003_gene3091	1.392e-38	167.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_1767650_1	1313172.YM304_34590	1.11e-130	434.0	COG0069@1|root,COG4638@1|root,COG0069@2|Bacteria,COG4638@2|Bacteria,2GN09@201174|Actinobacteria,4CMR1@84992|Acidimicrobiia	201174|Actinobacteria	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rieske
CMS3_k127_1767791_0	926550.CLDAP_27190	8.57e-208	691.0	COG1404@1|root,COG5640@1|root,COG1404@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	vpr	GO:0005575,GO:0005576	3.4.21.4	ko:K01312,ko:K14647	ko02024,ko04080,ko04972,ko04974,ko05164,map02024,map04080,map04972,map04974,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110,ko04147	-	-	-	FlgD_ig,Inhibitor_I9,PA,Peptidase_S8,SLH,Trypsin,VCBS
CMS3_k127_1767791_3	1123322.KB904702_gene141	2.731e-10	74.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria	201174|Actinobacteria	T	Signal transduction protein with Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
CMS3_k127_1767791_1	525904.Tter_0491	3.344e-51	187.0	COG0566@1|root,COG0566@2|Bacteria,2NQ0F@2323|unclassified Bacteria	2|Bacteria	J	tRNA rRNA methyltransferase	spoU	-	2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
CMS3_k127_1767791_2	985255.APHJ01000031_gene2757	1.016e-48	197.0	COG0823@1|root,COG2304@1|root,COG4254@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG4254@2|Bacteria,4PKD0@976|Bacteroidetes,1HWKJ@117743|Flavobacteriia,2P5SV@244698|Gillisia	976|Bacteroidetes	U	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
CMS3_k127_1774615_1	1121918.ARWE01000001_gene836	4.01e-39	153.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	mviM	-	1.1.1.18,1.1.1.369	ko:K00010,ko:K03810	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
CMS3_k127_1774615_0	1454004.AW11_02434	1.883e-64	239.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1KR1S@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	gtrA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1774615_2	1038867.AXAY01000010_gene1021	3.625e-36	148.0	2DWN5@1|root,3414V@2|Bacteria	2|Bacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
CMS3_k127_1774615_3	479434.Sthe_1634	1.067e-30	130.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,27YBK@189775|Thermomicrobia	189775|Thermomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS3_k127_1777028_1	420324.KI912045_gene4198	3.104e-23	102.0	COG1917@1|root,COG1917@2|Bacteria,1N1ZP@1224|Proteobacteria,2UE27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_1777028_2	314231.FP2506_02170	5.832e-21	100.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1777028_0	765420.OSCT_2114	1.903e-51	199.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_1777032_1	1499967.BAYZ01000077_gene871	2.2e-287	902.0	COG3250@1|root,COG3250@2|Bacteria,2NNR1@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2	manB2	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS3_k127_1777032_10	1122918.KB907280_gene254	4.297e-58	224.0	COG3934@1|root,COG3934@2|Bacteria,1VUFZ@1239|Firmicutes	1239|Firmicutes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5060
CMS3_k127_1777032_8	1117318.PRUB_24111	3.086e-66	238.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1RI4Q@1224|Proteobacteria,1SZJ1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
CMS3_k127_1777032_4	926550.CLDAP_13290	1.956e-133	435.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS3_k127_1777032_7	665571.STHERM_c13920	1.63e-81	282.0	COG1175@1|root,COG1175@2|Bacteria,2JAFT@203691|Spirochaetes	203691|Spirochaetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS3_k127_1777032_3	926550.CLDAP_13310	1.237e-153	501.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS3_k127_1777032_6	926550.CLDAP_13320	1.96e-82	286.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_1777032_0	1869.MB27_01440	0.0	1218.0	COG3459@1|root,COG3459@2|Bacteria,2IAZ0@201174|Actinobacteria,4DHXT@85008|Micromonosporales	201174|Actinobacteria	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
CMS3_k127_1777032_2	324602.Caur_1073	3.08e-275	873.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
CMS3_k127_1777032_5	926550.CLDAP_13280	3.043e-108	368.0	COG3534@1|root,COG3534@2|Bacteria,2G8SV@200795|Chloroflexi	200795|Chloroflexi	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1777032_9	68223.JNZY01000010_gene1688	2.038e-62	220.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1783630_0	926550.CLDAP_19470	2.38e-116	413.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_1783630_1	309801.trd_0510	1.408e-60	220.0	COG2421@1|root,COG2421@2|Bacteria	2|Bacteria	C	formamidase activity	-	-	3.5.1.4,3.5.1.49	ko:K01426,ko:K01455	ko00330,ko00360,ko00380,ko00460,ko00627,ko00630,ko00643,ko00910,ko01120,ko01200,map00330,map00360,map00380,map00460,map00627,map00630,map00643,map00910,map01120,map01200	-	R00524,R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025,RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
CMS3_k127_1783630_2	861299.J421_5728	4.549e-49	194.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_1783630_3	263358.VAB18032_18740	2.115e-22	108.0	COG0475@1|root,COG5207@1|root,COG0475@2|Bacteria,COG5207@2|Bacteria,2GJ69@201174|Actinobacteria,4DACZ@85008|Micromonosporales	201174|Actinobacteria	P	Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
CMS3_k127_1793146_3	1120947.ATUX01000007_gene896	7.578e-17	87.0	COG0395@1|root,COG0395@2|Bacteria,2GP5D@201174|Actinobacteria,4D3SU@85005|Actinomycetales	201174|Actinobacteria	P	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS3_k127_1793146_0	525904.Tter_2506	2.458e-85	292.0	COG1175@1|root,COG1175@2|Bacteria,2NQCB@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS3_k127_1793146_2	1385510.N781_03030	1.181e-32	143.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4H9TH@91061|Bacilli,2Y9BE@289201|Pontibacillus	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
CMS3_k127_1793146_1	861299.J421_0841	2.582e-61	226.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1807285_0	402777.KB235904_gene3359	9.026e-170	549.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS3_k127_1807285_1	1174528.JH992898_gene1861	9.057e-59	221.0	COG0265@1|root,COG2319@1|root,COG0265@2|Bacteria,COG2319@2|Bacteria,1G23Y@1117|Cyanobacteria	1117|Cyanobacteria	O	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2,WD40
CMS3_k127_1807285_2	1499967.BAYZ01000034_gene1071	7.045e-34	135.0	2E46N@1|root,32Z2M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1807285_4	66869.JNXG01000013_gene6833	1.85e-09	63.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulator, TraR DksA family	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS3_k127_1807285_3	1273538.G159_04930	1.372e-19	94.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26IIE@186818|Planococcaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_1808381_1	926569.ANT_27260	5.868e-40	155.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
CMS3_k127_1808381_0	926569.ANT_15860	2.552e-283	929.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
CMS3_k127_1815800_0	926550.CLDAP_33520	7.016e-176	566.0	COG1129@1|root,COG1129@2|Bacteria,2GBJG@200795|Chloroflexi	200795|Chloroflexi	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
CMS3_k127_1815800_2	926550.CLDAP_33510	2.134e-48	186.0	COG0619@1|root,COG0619@2|Bacteria,2G71W@200795|Chloroflexi	200795|Chloroflexi	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
CMS3_k127_1815800_1	926550.CLDAP_33500	5.558e-66	234.0	COG1122@1|root,COG1122@2|Bacteria,2G6FK@200795|Chloroflexi	200795|Chloroflexi	P	ECF transporter, substrate-specific component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF_trnsprt
CMS3_k127_1815800_3	1521187.JPIM01000080_gene1581	5.831e-23	109.0	COG1657@1|root,COG1657@2|Bacteria,2G7AD@200795|Chloroflexi,377CX@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1815800_4	443255.SCLAV_1557	2.23e-06	61.0	COG1657@1|root,COG1657@2|Bacteria,2GIRK@201174|Actinobacteria	201174|Actinobacteria	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
CMS3_k127_1826594_1	309801.trd_0392	7.351e-120	399.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_1826594_2	211165.AJLN01000047_gene6171	9.465e-111	368.0	COG1940@1|root,COG1940@2|Bacteria,1G4PJ@1117|Cyanobacteria,1JKM1@1189|Stigonemataceae	1117|Cyanobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_1826594_0	926569.ANT_12980	4.243e-196	660.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
CMS3_k127_1826594_6	1382356.JQMP01000004_gene182	0.0003717	49.0	COG5662@1|root,COG5662@2|Bacteria,2G96Y@200795|Chloroflexi,27YEM@189775|Thermomicrobia	189775|Thermomicrobia	K	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
CMS3_k127_1826594_5	1303518.CCALI_01207	7.306e-18	91.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	M1-584	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_1826594_4	867845.KI911784_gene1924	1.181e-18	100.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi,3757B@32061|Chloroflexia	32061|Chloroflexia	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
CMS3_k127_1826594_3	926569.ANT_27260	1.208e-82	301.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
CMS3_k127_1827003_1	926569.ANT_06180	8.588e-07	53.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
CMS3_k127_1827003_0	926569.ANT_11950	7.304e-202	647.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
CMS3_k127_1833680_1	357808.RoseRS_2229	6e-84	287.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1833680_3	443218.AS9A_3448	1.945e-62	240.0	COG0265@1|root,COG0265@2|Bacteria,2IB8S@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_1833680_2	357808.RoseRS_2229	3.895e-77	285.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1833680_6	1125863.JAFN01000001_gene405	9.933e-08	64.0	COG3291@1|root,COG3291@2|Bacteria,1NM1Z@1224|Proteobacteria,42XEW@68525|delta/epsilon subdivisions,2WSVZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1833680_4	1217720.ALOX01000047_gene1393	2.134e-48	185.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2JS6U@204441|Rhodospirillales	204441|Rhodospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS3_k127_1833680_0	316274.Haur_3267	5.175e-188	598.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_1833680_5	1090319.KE386571_gene2890	2.131e-27	116.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,2K5EC@204457|Sphingomonadales	204457|Sphingomonadales	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_1835854_5	1121447.JONL01000007_gene1216	1.175e-14	81.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MBCB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_1835854_0	398767.Glov_0611	3.974e-60	211.0	COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,42SPC@68525|delta/epsilon subdivisions,2WP55@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TIGRFAM Methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
CMS3_k127_1835854_6	1206739.BAGJ01000013_gene5249	5.401e-12	76.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4FUA9@85025|Nocardiaceae	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_1835854_2	330214.NIDE0557	7.497e-41	166.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
CMS3_k127_1835854_3	118161.KB235922_gene3251	8.353e-35	141.0	COG1100@1|root,COG1100@2|Bacteria,1G5QQ@1117|Cyanobacteria,3VJTG@52604|Pleurocapsales	1117|Cyanobacteria	S	TIGRFAM small GTP-binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Ras,Roc
CMS3_k127_1835854_1	326427.Cagg_2203	2.951e-44	166.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
CMS3_k127_1835854_4	926569.ANT_23640	5.306e-17	93.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
CMS3_k127_1840614_1	1324957.K933_11936	8.413e-149	483.0	COG0624@1|root,arCOG01107@2157|Archaea,2XU86@28890|Euryarchaeota,23ST7@183963|Halobacteria	183963|Halobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_1840614_0	502025.Hoch_4658	1.298e-201	652.0	COG1858@1|root,COG3420@1|root,COG1858@2|Bacteria,COG3420@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_1840614_5	316274.Haur_3763	6.132e-11	69.0	COG3474@1|root,COG3474@2|Bacteria,2GA7P@200795|Chloroflexi,3760W@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS3_k127_1840614_4	926550.CLDAP_35820	4.231e-37	143.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS3_k127_1840614_2	926550.CLDAP_35830	9.649e-119	393.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CMS3_k127_1840614_3	512565.AMIS_58690	2.461e-48	182.0	COG1752@1|root,COG1752@2|Bacteria,2IM69@201174|Actinobacteria	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_1840614_7	203122.Sde_2639	2.438e-06	49.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,1S295@1236|Gammaproteobacteria,466K7@72275|Alteromonadaceae	1236|Gammaproteobacteria	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
CMS3_k127_1842461_5	316274.Haur_4856	5.416e-13	83.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
CMS3_k127_1842461_0	1223410.KN050846_gene851	4.363e-159	541.0	COG4935@1|root,COG4935@2|Bacteria,4PNZU@976|Bacteroidetes,1I0B8@117743|Flavobacteriia	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,HYR,Peptidase_M36
CMS3_k127_1842461_2	243164.DET1226	1.534e-46	176.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi,34CM3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS3_k127_1842461_4	926569.ANT_04110	7.481e-26	113.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS3_k127_1842461_1	926569.ANT_13200	2.171e-143	468.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
CMS3_k127_1842461_3	251221.35214590	2.824e-30	123.0	COG1057@1|root,COG1057@2|Bacteria,1G5D2@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_1846081_2	662479.C440_08942	7.958e-07	57.0	COG0702@1|root,arCOG03015@2157|Archaea,2XT7V@28890|Euryarchaeota,23T9H@183963|Halobacteria	183963|Halobacteria	M	Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS3_k127_1846081_0	869210.Marky_0738	1.704e-67	240.0	COG1208@1|root,COG1208@2|Bacteria,1WJT1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	JM	COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CMS3_k127_1846081_1	635013.TherJR_2059	1.385e-57	203.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,260GP@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS3_k127_1846246_1	909663.KI867150_gene2301	7.236e-82	281.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_1846246_0	880073.Calab_2181	3.421e-85	290.0	COG0535@1|root,COG0535@2|Bacteria,2NPKA@2323|unclassified Bacteria	2|Bacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_1852570_1	926550.CLDAP_07340	3.9e-34	136.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_1852570_0	357808.RoseRS_0335	2.147e-53	203.0	COG1752@1|root,COG1752@2|Bacteria,2GAAT@200795|Chloroflexi,374T8@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_1853517_2	580340.Tlie_1444	3.041e-112	376.0	COG0124@1|root,COG0124@2|Bacteria,3TAI3@508458|Synergistetes	508458|Synergistetes	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS3_k127_1853517_3	926550.CLDAP_14750	1.534e-62	226.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS3_k127_1853517_4	326427.Cagg_0964	2.767e-19	99.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi,375TV@32061|Chloroflexia	32061|Chloroflexia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1853517_1	926550.CLDAP_00350	1.681e-154	506.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
CMS3_k127_1853517_0	329726.AM1_2452	6.127e-252	826.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_1853532_0	926560.KE387023_gene3595	1.009e-59	231.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS3_k127_1853532_1	1089550.ATTH01000001_gene731	2.981e-07	59.0	COG2318@1|root,COG2318@2|Bacteria,4NP2C@976|Bacteroidetes	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_1854018_0	452637.Oter_2022	1.273e-67	234.0	COG1028@1|root,COG1028@2|Bacteria	452637.Oter_2022|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1854018_1	1417296.U879_20655	8.549e-50	191.0	COG0010@1|root,COG0010@2|Bacteria,1N8KF@1224|Proteobacteria,2UN2I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_1854018_2	1229487.AMYW01000027_gene2790	5.415e-24	115.0	COG3064@1|root,COG3409@1|root,COG3064@2|Bacteria,COG3409@2|Bacteria,4NR0W@976|Bacteroidetes,1I8YH@117743|Flavobacteriia,2P0IZ@237|Flavobacterium	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,PG_binding_1
CMS3_k127_1854018_3	1229487.AMYW01000027_gene2790	8.975e-23	104.0	COG3064@1|root,COG3409@1|root,COG3064@2|Bacteria,COG3409@2|Bacteria,4NR0W@976|Bacteroidetes,1I8YH@117743|Flavobacteriia,2P0IZ@237|Flavobacterium	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,PG_binding_1
CMS3_k127_1854884_0	1173027.Mic7113_1748	1.135e-300	967.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ
CMS3_k127_1855534_4	517418.Ctha_0401	1.948e-27	118.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
CMS3_k127_1855534_1	517418.Ctha_0400	1.85e-71	246.0	COG1100@1|root,COG1100@2|Bacteria	2|Bacteria	S	GTP binding	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
CMS3_k127_1855534_0	517418.Ctha_0398	6.887e-73	254.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	DUF4388,Robl_LC7
CMS3_k127_1855534_2	517418.Ctha_0398	5.605e-42	157.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	DUF4388,Robl_LC7
CMS3_k127_1856805_0	941449.dsx2_3431	3.308e-197	620.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2M9RZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_1856805_1	452652.KSE_32510	1.033e-66	233.0	COG3173@1|root,COG3173@2|Bacteria,2I5QX@201174|Actinobacteria,2M3RC@2063|Kitasatospora	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_1856949_2	83406.HDN1F_21550	1.876e-10	73.0	COG5276@1|root,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
CMS3_k127_1856949_0	1121377.KB906401_gene3385	6.037e-52	194.0	29YCS@1|root,30K75@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1856949_1	1121946.AUAX01000004_gene526	7.461e-22	102.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4DGZM@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_1857595_0	765420.OSCT_1818	1.867e-06	60.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,376E7@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1860485_0	926550.CLDAP_36730	2.526e-176	561.0	COG1960@1|root,COG1960@2|Bacteria,2G5J5@200795|Chloroflexi	200795|Chloroflexi	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1860485_1	926550.CLDAP_14260	5.675e-136	441.0	COG3173@1|root,COG3173@2|Bacteria,2G5RM@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_1860485_2	309807.SRU_1831	9.735e-69	244.0	COG2267@1|root,COG2267@2|Bacteria,4PJWZ@976|Bacteroidetes,1FK2W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_1860485_3	357808.RoseRS_0812	5.564e-39	148.0	COG0659@1|root,COG0659@2|Bacteria,2G83D@200795|Chloroflexi,376RF@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS3_k127_1864966_7	926550.CLDAP_33740	6.524e-10	67.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
CMS3_k127_1864966_3	869210.Marky_1831	5.67e-61	215.0	COG0529@1|root,COG0529@2|Bacteria,1WK0X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS3_k127_1864966_1	886293.Sinac_5883	4.346e-159	515.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_1864966_0	926550.CLDAP_18760	1.093e-263	824.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
CMS3_k127_1864966_9	316274.Haur_3358	0.0001681	52.0	2AQIF@1|root,31FR6@2|Bacteria,2GB3Q@200795|Chloroflexi,377V2@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1864966_4	383372.Rcas_0143	1.354e-53	206.0	2DE6H@1|root,2ZKPY@2|Bacteria,2G9I8@200795|Chloroflexi,377JX@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1864966_5	765420.OSCT_2099	1.11e-42	179.0	COG1287@1|root,COG1287@2|Bacteria,2GBKX@200795|Chloroflexi,3781U@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1864966_8	102129.Lepto7375DRAFT_4234	3.631e-07	61.0	COG0392@1|root,COG0392@2|Bacteria,1G0E0@1117|Cyanobacteria,1H7E9@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0104)	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_1864966_6	91464.S7335_3977	1.869e-31	136.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
CMS3_k127_1864966_2	1223410.KN050846_gene2746	6.265e-68	239.0	COG2242@1|root,COG2242@2|Bacteria,4NV0U@976|Bacteroidetes	976|Bacteroidetes	H	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_1868488_0	1121405.dsmv_1498	2.379e-37	147.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42WJW@68525|delta/epsilon subdivisions,2WRIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS3_k127_1875087_3	926560.KE387023_gene3054	1.154e-16	86.0	2DMQT@1|root,32T2H@2|Bacteria,1WMUD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
CMS3_k127_1875087_2	717606.PaecuDRAFT_1776	5.587e-40	151.0	arCOG11412@1|root,31S84@2|Bacteria,1V6H1@1239|Firmicutes,4HJGG@91061|Bacilli,26XZS@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1875087_1	1382306.JNIM01000001_gene3330	1.02e-47	175.0	2ACY3@1|root,312JQ@2|Bacteria,2G8H3@200795|Chloroflexi	200795|Chloroflexi	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
CMS3_k127_1875087_0	1121946.AUAX01000015_gene6092	2.064e-146	479.0	COG3497@1|root,COG3497@2|Bacteria,2GMJA@201174|Actinobacteria,4DAV6@85008|Micromonosporales	201174|Actinobacteria	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
CMS3_k127_1876354_9	76114.ebA3146	9.641e-12	70.0	COG3787@1|root,COG3787@2|Bacteria,1PV3C@1224|Proteobacteria,2WB2H@28216|Betaproteobacteria,2KYQQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_1876354_5	693444.D782_1360	2.504e-84	284.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,2835N@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2311,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573	Flavoprotein
CMS3_k127_1876354_3	357808.RoseRS_0779	1.52e-96	342.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,377RQ@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1876354_4	1382306.JNIM01000001_gene3919	6.55e-86	289.0	COG2197@1|root,COG2197@2|Bacteria,2G6JC@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_1876354_2	266117.Rxyl_2612	5.321e-134	440.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4CRWF@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_1876354_1	765420.OSCT_2082	1.297e-152	547.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,2G8RP@200795|Chloroflexi	200795|Chloroflexi	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
CMS3_k127_1876354_6	118168.MC7420_3051	2.234e-63	252.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_1876354_8	926569.ANT_31290	3.956e-35	155.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
CMS3_k127_1876354_7	232348.ADXL01000063_gene2609	7.604e-51	189.0	COG4328@1|root,COG4328@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF429,RelA_SpoT
CMS3_k127_1876354_0	926569.ANT_15410	1.655e-230	744.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
CMS3_k127_1879689_0	105559.Nwat_1353	3.672e-20	108.0	COG5276@1|root,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria,1T2RF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
CMS3_k127_1879689_2	439481.Aboo_0153	7.678e-06	61.0	COG1572@1|root,arCOG03999@1|root,arCOG05978@1|root,arCOG02532@2157|Archaea,arCOG03999@2157|Archaea,arCOG05978@2157|Archaea,2Y4KU@28890|Euryarchaeota	28890|Euryarchaeota	E	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
CMS3_k127_1879689_1	1249975.JQLP01000003_gene76	2.398e-08	69.0	COG1361@1|root,COG3266@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3266@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1HZAG@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS3_k127_1882304_1	292459.STH1955	1.876e-09	70.0	COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,2498X@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,Peptidase_M28
CMS3_k127_1882304_0	228405.HNE_2307	1.544e-19	103.0	COG2234@1|root,COG2234@2|Bacteria,1MUZ7@1224|Proteobacteria,2TRSJ@28211|Alphaproteobacteria,43WZR@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_188426_2	479434.Sthe_0147	1.501e-26	119.0	COG0639@1|root,COG0639@2|Bacteria,2G71P@200795|Chloroflexi,27Y85@189775|Thermomicrobia	189775|Thermomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_188426_0	748280.NH8B_2717	1.727e-138	451.0	COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2VKYW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	fad dependent oxidoreductase	-	-	-	ko:K07222	-	-	-	-	ko00000	-	-	-	Pyr_redox_3
CMS3_k127_188426_1	311424.DhcVS_1445	2.29e-98	341.0	2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_188426_3	1125863.JAFN01000001_gene3471	1.095e-07	62.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,42X7G@68525|delta/epsilon subdivisions,2WSX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NnrU,PEMT
CMS3_k127_1886687_2	1121382.JQKG01000010_gene4728	5.885e-25	107.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_1886687_1	1121472.AQWN01000002_gene2269	6.572e-140	456.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS3_k127_1886687_0	56110.Oscil6304_0896	4.855e-146	478.0	COG0034@1|root,COG0034@2|Bacteria,1G1C9@1117|Cyanobacteria,1H8KH@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS3_k127_1886957_3	335543.Sfum_2229	2.887e-16	93.0	28IX5@1|root,2Z8V5@2|Bacteria,1R5YH@1224|Proteobacteria,42NTD@68525|delta/epsilon subdivisions,2WM4I@28221|Deltaproteobacteria,2MQZN@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1886957_1	861299.J421_6089	6.886e-103	352.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
CMS3_k127_1886957_2	67373.JOBF01000001_gene6276	3.811e-42	161.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_1886957_0	316274.Haur_1430	1.506e-142	494.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_1889997_2	926550.CLDAP_03020	1.06e-33	139.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi	200795|Chloroflexi	M	peptidase C60 sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS3_k127_1889997_0	401526.TcarDRAFT_0643	2.006e-99	333.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H7ID@909932|Negativicutes	909932|Negativicutes	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS3_k127_1889997_1	316274.Haur_1216	1.87e-57	211.0	COG0454@1|root,COG0456@2|Bacteria,2G9FH@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_1889997_3	316274.Haur_1215	1.486e-26	114.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02030,ko:K03407,ko:K07679,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,ko05133,map02020,map02030,map04112,map05133	M00236,M00477,M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.3	-	-	CHASE3,HATPase_c,HisKA,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_1889997_5	926569.ANT_06190	1.384e-17	87.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
CMS3_k127_1889997_4	4792.ETI32628	5.833e-22	109.0	28K3T@1|root,2QSIA@2759|Eukaryota,3QAGV@4776|Peronosporales	4776|Peronosporales	S	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CMS3_k127_1893861_0	1121377.KB906400_gene1412	4.444e-80	308.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_1893861_2	383372.Rcas_3701	5.572e-77	297.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS3_k127_1893861_1	526227.Mesil_3477	5.251e-79	304.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_1899003_1	1158601.I585_00316	4.716e-20	104.0	COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HIS1@91061|Bacilli,4AZW7@81852|Enterococcaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS3_k127_1899003_2	936574.HMPREF1508_1777	6.948e-06	58.0	COG4377@1|root,COG4377@2|Bacteria,1V4AU@1239|Firmicutes,25D57@186801|Clostridia	186801|Clostridia	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
CMS3_k127_1899003_0	255470.cbdbA1715	4.887e-42	161.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,34CZ8@301297|Dehalococcoidia	301297|Dehalococcoidia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_1899319_1	1173026.Glo7428_1817	5.941e-41	160.0	COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_1899319_3	1033740.CAEW01000016_gene2828	2.189e-25	119.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,26F3I@186818|Planococcaceae	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_1899319_0	404589.Anae109_2250	1.423e-188	611.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS3_k127_1899319_2	324925.Ppha_1227	1.3e-31	133.0	COG1051@1|root,COG1051@2|Bacteria,1FE2C@1090|Chlorobi	1090|Chlorobi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_1899319_5	342949.PNA2_1091	4.661e-06	55.0	COG0558@1|root,arCOG00670@2157|Archaea,2XWJ0@28890|Euryarchaeota,245EJ@183968|Thermococci	183968|Thermococci	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_1900378_1	329726.AM1_3493	6.303e-80	273.0	COG0847@1|root,COG0847@2|Bacteria,1G8Y7@1117|Cyanobacteria	1117|Cyanobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1900378_0	1172179.AUKV01000006_gene6089	1.16e-120	399.0	COG2124@1|root,COG2124@2|Bacteria,2IBKI@201174|Actinobacteria	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_1908150_0	926569.ANT_31600	1.023e-95	319.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2G82Q@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1909613_4	118166.JH976537_gene386	4.259e-34	136.0	COG0477@1|root,COG2814@2|Bacteria,1GQ8C@1117|Cyanobacteria,1HH9P@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_1909613_5	926550.CLDAP_10580	2.712e-22	107.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
CMS3_k127_1909613_3	192952.MM_1890	9.569e-70	250.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUW2@28890|Euryarchaeota,2N9TY@224756|Methanomicrobia	224756|Methanomicrobia	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS3_k127_1909613_1	1120959.ATXF01000011_gene340	6.627e-189	605.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4FKEP@85023|Microbacteriaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS3_k127_1909613_0	926550.CLDAP_08300	2.839e-253	788.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	200795|Chloroflexi	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS3_k127_1909613_2	255470.cbdbA861	2.641e-100	337.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,34CT4@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_1909733_2	1394178.AWOO02000040_gene8565	0.0005421	52.0	2EABA@1|root,334FH@2|Bacteria,2HY0R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
CMS3_k127_1909733_0	1173027.Mic7113_5799	1.186e-36	145.0	COG3339@1|root,COG3339@2|Bacteria,1G7DF@1117|Cyanobacteria,1HFS6@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS3_k127_1909733_1	1122605.KB893625_gene1920	1.586e-09	70.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PQQ_2,SLH
CMS3_k127_1919306_14	926569.ANT_10180	1.139e-36	139.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS3_k127_1919306_5	1295642.H839_00235	4.125e-68	235.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,1WE6E@129337|Geobacillus	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS3_k127_1919306_13	1304284.L21TH_0908	2.588e-40	152.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,36JQ0@31979|Clostridiaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS3_k127_1919306_6	926569.ANT_10210	2.038e-62	218.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi	200795|Chloroflexi	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS3_k127_1919306_17	383372.Rcas_4008	1.124e-16	81.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,375Z1@32061|Chloroflexia	32061|Chloroflexia	J	PFAM ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CMS3_k127_1919306_11	1274524.BSONL12_22084	3.244e-47	174.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1ZFMY@1386|Bacillus	91061|Bacilli	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS3_k127_1919306_0	926550.CLDAP_03900	1.518e-131	433.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi	200795|Chloroflexi	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS3_k127_1919306_3	926569.ANT_10250	2.753e-78	267.0	COG0563@1|root,COG0563@2|Bacteria,2G6GP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS3_k127_1919306_2	1329516.JPST01000015_gene697	2.411e-89	301.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,27B7R@186824|Thermoactinomycetaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS3_k127_1919306_18	309801.trd_0961	1.328e-11	65.0	COG0257@1|root,COG0257@2|Bacteria,2G7GJ@200795|Chloroflexi,27ZCS@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS3_k127_1919306_9	926569.ANT_10280	3.012e-52	186.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS3_k127_1919306_10	926569.ANT_10290	1.345e-51	185.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS3_k127_1919306_4	373903.Hore_01440	1.257e-75	259.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WACC@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS3_k127_1919306_1	926569.ANT_10310	2.241e-119	391.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS3_k127_1919306_15	1123239.KB898634_gene2881	6.856e-30	123.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli	91061|Bacilli	J	ribosomal protein l17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS3_k127_1919306_8	568816.Acin_0430	3.926e-58	211.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4H2Z4@909932|Negativicutes	909932|Negativicutes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS3_k127_1919306_7	292459.STH3041	1.323e-60	211.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS3_k127_1919306_12	926569.ANT_10350	7.351e-41	154.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS3_k127_1919306_16	357808.RoseRS_1334	2.177e-17	85.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi,375EZ@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
CMS3_k127_1923814_0	1173026.Glo7428_4014	6.399e-34	139.0	COG3551@1|root,COG3551@2|Bacteria,1G2AB@1117|Cyanobacteria	1117|Cyanobacteria	M	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_1932629_1	1123276.KB893272_gene2436	1.493e-129	428.0	COG3385@1|root,COG3385@2|Bacteria,4P02Y@976|Bacteroidetes,47TUA@768503|Cytophagia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CMS3_k127_1932629_5	1382359.JIAL01000001_gene1196	1.251e-14	84.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria,2JJTI@204432|Acidobacteriia	204432|Acidobacteriia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_1932629_2	357808.RoseRS_0325	5.288e-42	162.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1932629_0	926569.ANT_03860	2.286e-180	577.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_1932629_4	926569.ANT_03850	1.022e-23	112.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi	200795|Chloroflexi	T	SMART helix-turn-helix domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CMS3_k127_1932629_3	926569.ANT_03840	3.674e-32	135.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS3_k127_1932629_6	1101188.KI912156_gene4068	1.515e-12	76.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria,1W9SR@1268|Micrococcaceae	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
CMS3_k127_1934756_6	1122135.KB893167_gene2232	3.757e-28	121.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1934756_0	926569.ANT_07600	2.832e-109	359.0	COG0483@1|root,COG0483@2|Bacteria,2G7NN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
CMS3_k127_1934756_13	634498.mru_1169	1.411e-07	62.0	arCOG08979@1|root,arCOG08979@2157|Archaea	2157|Archaea	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1934756_2	634498.mru_1170	1.61e-53	218.0	COG1401@1|root,COG4127@1|root,arCOG03779@2157|Archaea,arCOG05194@2157|Archaea,2XTIK@28890|Euryarchaeota	28890|Euryarchaeota	V	ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,DUF3578,EVE
CMS3_k127_1934756_7	324602.Caur_2874	6.297e-21	111.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS3_k127_1934756_11	4533.OB04G23400.1	8.662e-11	77.0	KOG4351@1|root,KOG4582@1|root,KOG4351@2759|Eukaryota,KOG4582@2759|Eukaryota,37HVT@33090|Viridiplantae,3GCJ1@35493|Streptophyta,3KQD0@4447|Liliopsida,3I79P@38820|Poales	35493|Streptophyta	S	Ig-like domain from next to BRCA1 gene	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1,ZZ
CMS3_k127_1934756_15	1116375.VEJY3_23541	0.0001693	51.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,1XURR@135623|Vibrionales	135623|Vibrionales	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1934756_8	1379698.RBG1_1C00001G1210	8.198e-15	87.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_1934756_1	880073.Calab_2417	1.163e-56	203.0	COG1100@1|root,COG1100@2|Bacteria,2NPDD@2323|unclassified Bacteria	2|Bacteria	K	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
CMS3_k127_1934756_10	1499967.BAYZ01000186_gene3952	2.34e-13	77.0	COG2018@1|root,COG2018@2|Bacteria,2NQXH@2323|unclassified Bacteria	2|Bacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
CMS3_k127_1934756_14	439235.Dalk_2438	9.778e-06	56.0	COG0664@1|root,COG0664@2|Bacteria,1RCF4@1224|Proteobacteria,43BRQ@68525|delta/epsilon subdivisions,2X72K@28221|Deltaproteobacteria,2MJHW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,cNMP_binding
CMS3_k127_1934756_9	197221.22295715	2.118e-14	80.0	COG0840@1|root,COG0840@2|Bacteria,1GQ8Q@1117|Cyanobacteria	1117|Cyanobacteria	NT	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	Protoglobin
CMS3_k127_1934756_4	316274.Haur_1577	5.831e-36	139.0	COG4753@1|root,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1934756_5	926569.ANT_11750	2.813e-33	139.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1934756_3	324602.Caur_0960	3.799e-52	198.0	COG4191@1|root,COG4191@2|Bacteria,2GBJB@200795|Chloroflexi,375H4@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_1936467_3	1382359.JIAL01000001_gene2092	3.43e-06	53.0	COG1437@1|root,COG1437@2|Bacteria,3Y4V3@57723|Acidobacteria,2JJIG@204432|Acidobacteriia	204432|Acidobacteriia	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
CMS3_k127_1936467_2	794903.OPIT5_14435	2.289e-31	133.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_1936467_1	926550.CLDAP_21630	4.93e-197	626.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_1936467_0	926550.CLDAP_21610	1.195e-249	779.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_1937703_0	1379698.RBG1_1C00001G1789	6.668e-53	214.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
CMS3_k127_1937703_3	682795.AciX8_1484	5.358e-07	58.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS3_k127_1937703_2	316274.Haur_0938	4.137e-07	62.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,2GAIX@200795|Chloroflexi,376FU@32061|Chloroflexia	32061|Chloroflexia	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_1937703_1	331869.BAL199_10652	3.263e-08	64.0	COG1132@1|root,COG1132@2|Bacteria,1MWTY@1224|Proteobacteria,2TRSY@28211|Alphaproteobacteria,4BP58@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran,cNMP_binding
CMS3_k127_1938454_4	402626.Rpic_2446	2.845e-51	196.0	COG2342@1|root,COG2342@2|Bacteria,1N2HD@1224|Proteobacteria,2W5MT@28216|Betaproteobacteria,1K6RZ@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycoside-hydrolase family GH114	-	-	6.1.1.16	ko:K01884	ko00970,map00970	M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Glyco_hydro_114
CMS3_k127_1938454_0	761193.Runsl_1927	3.142e-213	670.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,47M1X@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_1938454_2	526227.Mesil_3299	1.518e-121	394.0	COG1028@1|root,COG1028@2|Bacteria,1WM8P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_1938454_3	99598.Cal7507_4057	2.264e-83	289.0	COG3850@1|root,COG3850@2|Bacteria,1GJRF@1117|Cyanobacteria,1HR3E@1161|Nostocales	1117|Cyanobacteria	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
CMS3_k127_1938454_1	1121930.AQXG01000002_gene1952	7.007e-165	543.0	COG1042@1|root,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,1IVTU@117747|Sphingobacteriia	976|Bacteroidetes	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CMS3_k127_1939670_0	926550.CLDAP_24180	2.176e-138	445.0	COG0667@1|root,COG0667@2|Bacteria,2G7T1@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_1939670_1	1122176.KB903539_gene1317	7.582e-53	189.0	COG1917@1|root,COG1917@2|Bacteria,4NR0K@976|Bacteroidetes,1IT3Z@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS3_k127_1939670_3	926569.ANT_07630	5.053e-50	179.0	COG0656@1|root,COG0656@2|Bacteria,2G5JK@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS3_k127_1939670_2	485913.Krac_3115	1.229e-51	199.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_1946518_5	926569.ANT_30540	1.12e-05	53.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1946518_0	1033991.RLEG12_19575	2.642e-141	455.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2UPD7@28211|Alphaproteobacteria,4BAX9@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_1946518_1	326427.Cagg_0866	6.622e-106	355.0	COG2040@1|root,COG2040@2|Bacteria	2|Bacteria	E	homocysteine	mmuM	GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS3_k127_1946518_4	402881.Plav_1643	2.477e-24	113.0	COG1670@1|root,COG1670@2|Bacteria,1RFBQ@1224|Proteobacteria,2UEWR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_1946518_3	1123366.TH3_11690	2.861e-70	248.0	COG0697@1|root,COG0697@2|Bacteria,1R4G2@1224|Proteobacteria,2TTS7@28211|Alphaproteobacteria,2JY6M@204441|Rhodospirillales	204441|Rhodospirillales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_1946518_2	479434.Sthe_1856	1.643e-89	302.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,27XRQ@189775|Thermomicrobia	189775|Thermomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_1951705_2	1248916.ANFY01000007_gene2235	0.0008741	42.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2K0DQ@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO,ThiG
CMS3_k127_1951705_0	1348663.KCH_37230	1.496e-19	101.0	COG3675@1|root,COG3675@2|Bacteria,2GND0@201174|Actinobacteria	201174|Actinobacteria	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CMS3_k127_1951705_1	1184609.KILIM_038_00090	2.464e-05	52.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4F7XN@85018|Dermatophilaceae	201174|Actinobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174,ko:K07038	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS3_k127_1967434_4	118168.MC7420_7104	4.051e-16	81.0	COG3825@1|root,COG3825@2|Bacteria,1G1TM@1117|Cyanobacteria,1HBDN@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_1967434_2	221288.JH992900_gene78	8.314e-33	150.0	COG0745@1|root,COG1672@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,1G3JV@1117|Cyanobacteria	1117|Cyanobacteria	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_8
CMS3_k127_1967434_5	197221.22295064	5.036e-07	64.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
CMS3_k127_1967434_3	861299.J421_3658	1.024e-26	130.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_3658|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_1967434_1	357808.RoseRS_1669	2.298e-42	181.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
CMS3_k127_1967434_0	926569.ANT_11730	6.06e-104	348.0	COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS3_k127_1972242_2	926569.ANT_16180	4.61e-74	256.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_1972242_0	926569.ANT_16170	1.458e-201	634.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS3_k127_1972242_3	471854.Dfer_4216	1.94e-10	70.0	COG0671@1|root,COG0671@2|Bacteria,4NUPJ@976|Bacteroidetes,47PT7@768503|Cytophagia	976|Bacteroidetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1972242_4	211114.JOEF01000015_gene3530	5.55e-07	61.0	2DB8K@1|root,2Z7S1@2|Bacteria,2IH44@201174|Actinobacteria	201174|Actinobacteria	S	Streptomycin adenylyltransferase	-	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
CMS3_k127_1972242_1	247490.KSU1_C1426	3.854e-105	353.0	COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
CMS3_k127_1972242_5	1056512.D515_02060	0.0002702	53.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,1XVP4@135623|Vibrionales	135623|Vibrionales	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS3_k127_1974729_1	1131269.AQVV01000005_gene388	6.882e-21	102.0	COG3639@1|root,COG3639@2|Bacteria	2|Bacteria	P	organic phosphonate transmembrane transporter activity	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
CMS3_k127_1974729_0	1307761.L21SP2_1483	4.687e-98	327.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
CMS3_k127_1976783_0	1122176.KB903548_gene1179	4.203e-125	437.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4NUFW@976|Bacteroidetes,1IZ0P@117747|Sphingobacteriia	976|Bacteroidetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
CMS3_k127_198925_1	316274.Haur_1890	5.346e-58	207.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,2G774@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_198925_0	316274.Haur_1889	2.343e-92	317.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_198925_3	1128427.KB904821_gene3582	5.252e-05	58.0	COG0265@1|root,COG0265@2|Bacteria,1G0XN@1117|Cyanobacteria,1H8PC@1150|Oscillatoriales	1117|Cyanobacteria	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PPC,Trypsin_2
CMS3_k127_198925_2	526225.Gobs_1160	7.018e-48	199.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,TIR_2,WD40
CMS3_k127_1992625_0	715226.ABI_06160	2.565e-112	371.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,2KFBN@204458|Caulobacterales	204458|Caulobacterales	I	carboxyl transferase	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_1992625_2	1128427.KB904821_gene4073	5.319e-36	140.0	COG2361@1|root,COG2361@2|Bacteria,1G7XA@1117|Cyanobacteria,1HCYZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS3_k127_1992625_3	751945.Theos_1242	1.344e-18	89.0	COG1669@1|root,COG1669@2|Bacteria,1WKBN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS3_k127_1992625_1	557599.MKAN_28620	1.573e-81	295.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,235HD@1762|Mycobacteriaceae	201174|Actinobacteria	L	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,PD40,TIR_2,WD40
CMS3_k127_1997495_5	383372.Rcas_2818	5.254e-33	136.0	COG1652@1|root,COG1652@2|Bacteria,2G7PE@200795|Chloroflexi	200795|Chloroflexi	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_1997495_1	195250.CM001776_gene1459	3.344e-106	365.0	COG3501@1|root,COG3501@2|Bacteria,1G3M3@1117|Cyanobacteria,1H2VK@1129|Synechococcus	1117|Cyanobacteria	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
CMS3_k127_1997495_4	1206777.B195_19798	2.608e-42	158.0	2ANY6@1|root,31DZ3@2|Bacteria,1RIZN@1224|Proteobacteria,1S77G@1236|Gammaproteobacteria,1ZA6D@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
CMS3_k127_1997495_3	1382306.JNIM01000001_gene3322	1.331e-44	165.0	COG3628@1|root,COG3628@2|Bacteria,2G7CQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM GPW gp25 family protein	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
CMS3_k127_1997495_0	1382306.JNIM01000001_gene3321	1.487e-182	592.0	COG3299@1|root,COG3299@2|Bacteria,2G84U@200795|Chloroflexi	200795|Chloroflexi	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CMS3_k127_1997495_2	357808.RoseRS_1669	4.456e-78	271.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
CMS3_k127_200236_2	558169.AGAV01000003_gene2757	2.121e-16	87.0	COG1562@1|root,COG1562@2|Bacteria,1TRWV@1239|Firmicutes,4HAFU@91061|Bacilli	91061|Bacilli	I	Phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
CMS3_k127_200236_1	926550.CLDAP_35480	4.854e-49	192.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
CMS3_k127_200236_3	1179773.BN6_04910	6.187e-05	52.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4E3DV@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	-	-	-	-	-	-	-	-	-	COXG
CMS3_k127_200236_0	697281.Mahau_0771	1.389e-57	204.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS3_k127_2013047_5	926550.CLDAP_40040	3.088e-38	150.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
CMS3_k127_2013047_6	926569.ANT_19460	2.548e-30	128.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS3_k127_2013047_0	926550.CLDAP_40030	1.482e-170	557.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS3_k127_2013047_7	926569.ANT_19490	5.296e-24	108.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CMS3_k127_2013047_1	357808.RoseRS_1320	3.689e-142	460.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi,375H7@32061|Chloroflexia	32061|Chloroflexia	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
CMS3_k127_2013047_2	383372.Rcas_1632	8.653e-138	449.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi,375FD@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_2013047_3	357808.RoseRS_1318	4.336e-133	432.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi,374T2@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_2013047_4	1254432.SCE1572_44700	8.24e-79	267.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,42NTY@68525|delta/epsilon subdivisions,2WK4F@28221|Deltaproteobacteria,2YUKQ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
CMS3_k127_2014321_1	552811.Dehly_0569	9.377e-78	274.0	COG3568@1|root,COG3568@2|Bacteria,2G7ER@200795|Chloroflexi,34CM1@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_2014321_0	926569.ANT_26670	5.644e-232	731.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_2014321_4	1499967.BAYZ01000034_gene1071	2.426e-31	128.0	2E46N@1|root,32Z2M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2014321_5	644283.Micau_0299	1.042e-07	59.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D8HK@85008|Micromonosporales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2014321_2	926550.CLDAP_21010	3.393e-60	225.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_2014321_3	886293.Sinac_4302	5.578e-58	207.0	COG3266@1|root,COG4655@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4655@2|Bacteria,COG4932@2|Bacteria,2IZVN@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function (DUF3494)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF3494
CMS3_k127_2016103_5	1128421.JAGA01000001_gene2006	3.545e-31	127.0	COG2363@1|root,COG2363@2|Bacteria,2NRMS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS3_k127_2016103_7	313612.L8106_25957	7.317e-22	98.0	COG0607@1|root,COG0607@2|Bacteria,1G7VW@1117|Cyanobacteria,1HBNV@1150|Oscillatoriales	1117|Cyanobacteria	P	Rhodanese-related sulfurtransferase	pspE	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_2016103_3	526225.Gobs_3543	2.581e-44	172.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4ESC8@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2016103_2	926550.CLDAP_38550	3.635e-85	302.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_2016103_1	867845.KI911784_gene2547	2.276e-87	326.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeY	-	-	ko:K05385	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	CHAT,DUF1822,HEAT_2,Lipase_GDSL_2,Vitellogenin_N
CMS3_k127_2016103_4	926550.CLDAP_39890	8.583e-33	140.0	28HJF@1|root,2Z7UK@2|Bacteria,2G862@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016103_0	391625.PPSIR1_20789	5.977e-162	531.0	COG4870@1|root,COG4870@2|Bacteria,1Q2ZQ@1224|Proteobacteria,438PA@68525|delta/epsilon subdivisions,2X3X1@28221|Deltaproteobacteria,2YXEN@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase C1 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2016103_6	765420.OSCT_0232	9.631e-28	123.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Cytochrom_C,DUF4132,HEAT_2,cNMP_binding
CMS3_k127_2018909_1	926550.CLDAP_31360	1.182e-88	308.0	2DZNW@1|root,32VEY@2|Bacteria,2G8XI@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2018909_2	1167006.UWK_01513	1.307e-43	183.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2MN5F@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
CMS3_k127_2018909_3	926569.ANT_00400	1.827e-40	163.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2018909_0	926569.ANT_00390	1.238e-105	364.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
CMS3_k127_2018909_4	926569.ANT_00380	1.354e-27	120.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2022170_0	761193.Runsl_1400	9.226e-211	660.0	COG2368@1|root,COG2368@2|Bacteria,4NKNT@976|Bacteroidetes	976|Bacteroidetes	Q	4-hydroxybutyryl-CoA dehydratase	abfD	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
CMS3_k127_2022170_1	653733.Selin_2179	1.637e-06	59.0	COG1148@1|root,COG1149@1|root,COG1148@2|Bacteria,COG1149@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.1.2,1.3.7.1	ko:K00176,ko:K00207,ko:K00528,ko:K03737,ko:K20449	ko00010,ko00020,ko00240,ko00410,ko00620,ko00650,ko00720,ko00760,ko00770,ko00983,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00240,map00410,map00620,map00650,map00720,map00760,map00770,map00983,map01100,map01120,map01130,map01200	M00009,M00011,M00046,M00173,M00307,M00620	R00978,R01196,R01197,R01415,R03164,R08226,R10159,R10866	RC00004,RC00072,RC00123,RC02245,RC02422,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_4,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_2026507_0	290397.Adeh_2304	1.743e-35	136.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3,1.8.5.5	ko:K07306,ko:K08352	ko00920,ko01120,map00920,map01120	-	R09501,R10149	RC02555,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_2026507_1	345341.KUTG_01706	1.514e-09	69.0	COG3173@1|root,COG3173@2|Bacteria,2H6ZZ@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_2026507_2	886293.Sinac_2227	0.0005888	46.0	COG3509@1|root,COG3509@2|Bacteria,2J04W@203682|Planctomycetes	203682|Planctomycetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CMS3_k127_2030001_2	269797.Mbar_A1046	1.14e-22	108.0	COG1668@1|root,arCOG01462@2157|Archaea,2XX4X@28890|Euryarchaeota,2NAR7@224756|Methanomicrobia	224756|Methanomicrobia	C	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_2030001_1	1128421.JAGA01000003_gene3199	2.898e-65	239.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_2030001_0	316274.Haur_2672	3.399e-97	326.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	ecsA_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_2030001_4	324602.Caur_1222	0.0006514	50.0	COG0204@1|root,COG0204@2|Bacteria,2GACB@200795|Chloroflexi,37578@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_2030001_3	479434.Sthe_3033	2.635e-15	77.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_20317_4	485913.Krac_2665	2.491e-86	301.0	COG0477@1|root,COG2814@2|Bacteria,2G8CV@200795|Chloroflexi	2|Bacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_20317_1	1236902.ANAS01000047_gene2289	2.971e-147	485.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
CMS3_k127_20317_0	1047013.AQSP01000113_gene740	2.306e-303	952.0	COG1472@1|root,COG1472@2|Bacteria,2NNR4@2323|unclassified Bacteria	2|Bacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
CMS3_k127_20317_3	926550.CLDAP_20940	3.943e-109	362.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_20317_5	1183438.GKIL_1244	6.563e-30	134.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CMS3_k127_20317_6	991.IW20_06635	1.954e-11	77.0	COG0842@1|root,COG0842@2|Bacteria,4NGFA@976|Bacteroidetes,1HYPT@117743|Flavobacteriia,2NSMK@237|Flavobacterium	976|Bacteroidetes	V	Transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_20317_2	926569.ANT_00880	4.928e-143	478.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_2032914_4	439235.Dalk_1773	7.501e-31	122.0	COG2161@1|root,COG2161@2|Bacteria,1N07B@1224|Proteobacteria,42UIW@68525|delta/epsilon subdivisions,2WQU3@28221|Deltaproteobacteria,2MKSY@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
CMS3_k127_2032914_3	1158756.AQXQ01000008_gene2383	7.91e-37	140.0	COG4115@1|root,COG4115@2|Bacteria,1N0WH@1224|Proteobacteria,1S8ZF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Addiction module toxin, Txe YoeB	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin,YoeB_toxin
CMS3_k127_2032914_0	1177928.TH2_04778	5.772e-209	654.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,2JPB4@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2032914_1	485913.Krac_2223	9.058e-68	243.0	arCOG10517@1|root,31Y5Z@2|Bacteria,2G8TN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2032914_2	485913.Krac_5165	4.351e-49	181.0	COG2320@1|root,COG2320@2|Bacteria	2|Bacteria	Q	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
CMS3_k127_2034189_1	489825.LYNGBM3L_55270	9.988e-30	132.0	COG1357@1|root,COG1357@2|Bacteria,1G42W@1117|Cyanobacteria,1H9P7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_2034189_0	1297742.A176_01222	1.037e-67	252.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8,Trypsin_2
CMS3_k127_2046638_3	1304865.JAGF01000001_gene2184	3.631e-17	88.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_2046638_0	926569.ANT_17850	7.13e-86	289.0	COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi	200795|Chloroflexi	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K03189,ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
CMS3_k127_2046638_1	1395587.P364_0100595	1.062e-52	191.0	COG0454@1|root,COG0456@2|Bacteria,1V81Z@1239|Firmicutes,4HIXF@91061|Bacilli,275IW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS3_k127_2046638_4	485913.Krac_1629	1.084e-08	67.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,PD40,Pentapeptide,Pkinase,TIR_2,WD40
CMS3_k127_2046638_2	455632.SGR_278	2.511e-42	162.0	COG0318@1|root,COG1020@1|root,COG3321@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria,41CBC@629295|Streptomyces griseus group	201174|Actinobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
CMS3_k127_2048385_0	268407.PWYN_16505	5.329e-216	687.0	COG0577@1|root,COG0577@2|Bacteria,1TQ3S@1239|Firmicutes,4HCJ4@91061|Bacilli,26RXF@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS3_k127_2048385_1	1415780.JPOG01000001_gene2343	5.182e-26	119.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria,1X3EM@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS3_k127_2051120_5	324602.Caur_1800	5.639e-84	283.0	COG4586@1|root,COG4586@2|Bacteria,2G88B@200795|Chloroflexi,376NY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2051120_8	326427.Cagg_2513	1.527e-54	202.0	COG4587@1|root,COG4587@2|Bacteria,2G9N0@200795|Chloroflexi,37604@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_2051120_7	867845.KI911784_gene2250	4.039e-63	226.0	COG3694@1|root,COG3694@2|Bacteria,2G90J@200795|Chloroflexi,377JE@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_2051120_3	497964.CfE428DRAFT_2365	2.272e-131	426.0	COG1090@1|root,COG1090@2|Bacteria	2|Bacteria	S	coenzyme binding	yfcH	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS3_k127_2051120_9	479431.Namu_3218	3.887e-34	142.0	2A651@1|root,30UXH@2|Bacteria,2IERM@201174|Actinobacteria,4EVQT@85013|Frankiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
CMS3_k127_2051120_10	1108045.GORHZ_040_00160	2.041e-29	125.0	COG1309@1|root,COG1309@2|Bacteria,2IN1Z@201174|Actinobacteria,4GEX4@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2051120_2	357808.RoseRS_0270	1.313e-147	492.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_2051120_0	357808.RoseRS_0270	1.301e-168	555.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_2051120_1	357808.RoseRS_0270	2.26e-165	544.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_2051120_4	211114.JOEF01000004_gene6604	3.444e-89	310.0	28XJV@1|root,2ZJGZ@2|Bacteria,2I3N6@201174|Actinobacteria,4E08F@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2051120_12	211114.JOEF01000004_gene6603	1.148e-05	53.0	2DSS6@1|root,33H8G@2|Bacteria,2HUXA@201174|Actinobacteria,4E6MB@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2051120_11	518766.Rmar_1429	1.053e-15	90.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,YceI
CMS3_k127_2051120_6	926550.CLDAP_35360	1.281e-64	230.0	COG1994@1|root,COG1994@2|Bacteria,2G8E2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_2055352_4	926569.ANT_19030	9.574e-57	202.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS3_k127_2055352_7	926569.ANT_19040	9.357e-18	86.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2055352_8	188626.HMPREF0321_0633	1.225e-17	87.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,1ZWYA@145357|Dermacoccaceae	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_2055352_6	357808.RoseRS_3697	1.625e-36	144.0	COG3428@1|root,COG3428@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CMS3_k127_2055352_2	926550.CLDAP_35570	1.282e-77	270.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_2055352_1	316274.Haur_4664	3.161e-80	282.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_2055352_3	457429.ABJI02000143_gene1225	4.045e-68	245.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2055352_5	1122134.KB893650_gene1447	1.986e-48	178.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,1T01J@1236|Gammaproteobacteria,1XRPC@135619|Oceanospirillales	135619|Oceanospirillales	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
CMS3_k127_2055352_0	1121918.ARWE01000001_gene1360	1.043e-139	452.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	E	PFAM Cys Met metabolism	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_2056902_0	1499967.BAYZ01000015_gene6576	7.946e-59	232.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	MA20_35625	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Peripla_BP_3
CMS3_k127_2056902_1	255470.cbdbA1039	7.548e-45	185.0	COG4166@1|root,COG4166@2|Bacteria,2G81T@200795|Chloroflexi,34DKF@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_2056902_2	1123354.AUDR01000013_gene719	0.0001267	49.0	COG4691@1|root,COG4691@2|Bacteria,1N8BI@1224|Proteobacteria,2VVWB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Plasmid stability protein	stbC	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	Arc
CMS3_k127_2058331_2	926550.CLDAP_31200	5.135e-43	161.0	COG0239@1|root,COG0239@2|Bacteria,2G760@200795|Chloroflexi	200795|Chloroflexi	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS3_k127_2058331_1	926550.CLDAP_31210	7.371e-140	457.0	COG0517@1|root,COG1993@1|root,COG0517@2|Bacteria,COG1993@2|Bacteria,2G69Z@200795|Chloroflexi	200795|Chloroflexi	T	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF190
CMS3_k127_2058331_0	926569.ANT_27070	9.341e-239	754.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_2061295_2	1122223.KB890699_gene613	1.825e-32	138.0	COG3055@1|root,COG3055@2|Bacteria,1WK3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
CMS3_k127_2061295_4	644966.Tmar_2152	9.157e-14	77.0	COG3224@1|root,COG3224@2|Bacteria,1V83H@1239|Firmicutes	1239|Firmicutes	S	Ethyl tert-butyl ether degradation	ethD	-	-	-	-	-	-	-	-	-	-	-	EthD
CMS3_k127_2061295_0	926569.ANT_25910	3.121e-99	343.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS3_k127_2061295_1	1242864.D187_006669	5.717e-54	202.0	COG1657@1|root,COG1657@2|Bacteria,1MVWK@1224|Proteobacteria,439E4@68525|delta/epsilon subdivisions,2X4P3@28221|Deltaproteobacteria,2YZBY@29|Myxococcales	28221|Deltaproteobacteria	I	Squalene-hopene cyclase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SQHop_cyclase_C
CMS3_k127_2061295_3	530564.Psta_1738	1.252e-31	126.0	COG1657@1|root,COG1657@2|Bacteria,2IXWT@203682|Planctomycetes	203682|Planctomycetes	I	COG1657 Squalene cyclase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
CMS3_k127_2061527_1	504472.Slin_0892	2.753e-16	89.0	28KQG@1|root,2ZA89@2|Bacteria,4NKET@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
CMS3_k127_2061527_0	861299.J421_0654	2.354e-74	261.0	29XIJ@1|root,30J9H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2061527_2	1089545.KB913037_gene479	8.797e-12	77.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DYVZ@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2062427_0	1353531.AZNX01000014_gene3221	8.227e-96	329.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_2062787_1	926569.ANT_15870	1.79e-91	326.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
CMS3_k127_2062787_2	1173027.Mic7113_4359	2.156e-16	85.0	COG3809@1|root,COG3809@2|Bacteria,1GAWM@1117|Cyanobacteria,1HHMU@1150|Oscillatoriales	1117|Cyanobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
CMS3_k127_2062787_0	552811.Dehly_0558	9.913e-106	362.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_2065481_0	1254432.SCE1572_13245	1.148e-195	645.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2X4FQ@28221|Deltaproteobacteria,2YYXH@29|Myxococcales	28221|Deltaproteobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_23,PP-binding
CMS3_k127_2065481_3	1209984.BN978_03267	0.0004815	49.0	2C1AE@1|root,32QZN@2|Bacteria,2IIC0@201174|Actinobacteria,233QY@1762|Mycobacteriaceae	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_2065481_2	525904.Tter_2661	1.229e-43	168.0	COG2365@1|root,COG2365@2|Bacteria,2NRBJ@2323|unclassified Bacteria	2|Bacteria	T	Tyrosine phosphatase family	iphP	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
CMS3_k127_2065481_1	926560.KE387027_gene519	7.161e-46	171.0	COG2045@1|root,COG2045@2|Bacteria,1WMIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	2-phosphosulpholactate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	2-ph_phosp
CMS3_k127_2075521_6	679926.Mpet_0486	1.432e-58	208.0	arCOG14808@1|root,arCOG14808@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CMS3_k127_2075521_7	316274.Haur_1490	1.002e-53	199.0	COG3025@1|root,COG3025@2|Bacteria,2G8K8@200795|Chloroflexi,377DB@32061|Chloroflexia	32061|Chloroflexia	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS3_k127_2075521_1	1128421.JAGA01000003_gene3536	2.181e-132	438.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_2075521_3	1128421.JAGA01000003_gene3537	1.314e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2075521_4	926550.CLDAP_24200	5.352e-88	299.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
CMS3_k127_2075521_8	1128421.JAGA01000003_gene3538	4.151e-51	190.0	COG2353@1|root,COG2353@2|Bacteria,2NR1J@2323|unclassified Bacteria	2|Bacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_2075521_2	1237500.ANBA01000009_gene1044	4.754e-114	380.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4EGXC@85012|Streptosporangiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
CMS3_k127_2075521_5	926550.CLDAP_26300	4.768e-70	241.0	COG0503@1|root,COG0503@2|Bacteria,2G71F@200795|Chloroflexi	200795|Chloroflexi	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS3_k127_2075521_0	926569.ANT_30340	1.58e-174	564.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS3_k127_2097359_1	335543.Sfum_4027	2.78e-70	250.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MQDN@213462|Syntrophobacterales	1224|Proteobacteria	KT	Stage II sporulation	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2,sCache_2
CMS3_k127_2097359_5	326427.Cagg_2441	5.79e-07	59.0	COG3103@1|root,COG3103@2|Bacteria,2G7IJ@200795|Chloroflexi,377K8@32061|Chloroflexia	32061|Chloroflexia	T	PFAM SH3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
CMS3_k127_2097359_0	316274.Haur_0810	7.298e-199	641.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi,3756T@32061|Chloroflexia	32061|Chloroflexia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS3_k127_2097359_2	1120973.AQXL01000129_gene2484	4.727e-43	167.0	COG0546@1|root,COG0546@2|Bacteria,1V3MH@1239|Firmicutes,4HFNF@91061|Bacilli,278CT@186823|Alicyclobacillaceae	91061|Bacilli	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS3_k127_2097359_3	926569.ANT_20880	5.641e-26	113.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_2097782_0	316274.Haur_2224	2.379e-109	380.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,VanZ
CMS3_k127_2107500_0	309807.SRU_1394	4.941e-36	152.0	COG1630@1|root,COG1630@2|Bacteria,4PE9Y@976|Bacteroidetes,1FIMR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
CMS3_k127_210885_3	518766.Rmar_2430	1.308e-34	136.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes	976|Bacteroidetes	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_210885_0	1128421.JAGA01000002_gene1788	2.406e-173	558.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_210885_1	357808.RoseRS_0384	9.213e-156	501.0	COG0330@1|root,COG0330@2|Bacteria,2GAIW@200795|Chloroflexi,376FS@32061|Chloroflexia	32061|Chloroflexia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_210885_2	926569.ANT_12920	1.797e-44	177.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
CMS3_k127_210885_6	1122939.ATUD01000002_gene1347	1.489e-09	63.0	2EJ72@1|root,33CY7@2|Bacteria,2GXXX@201174|Actinobacteria,4CTT9@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_210885_4	1547437.LL06_23285	1.099e-29	125.0	COG0454@1|root,COG0456@2|Bacteria,1N29T@1224|Proteobacteria,2UF3Q@28211|Alphaproteobacteria,43PNS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_211068_0	926550.CLDAP_13490	1.473e-251	801.0	COG1205@1|root,COG1403@1|root,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
CMS3_k127_211068_1	324057.Pjdr2_0475	1.143e-162	527.0	COG3250@1|root,COG3250@2|Bacteria,1UJEA@1239|Firmicutes,4IT6P@91061|Bacilli,2778E@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS3_k127_2120148_1	452637.Oter_1683	1.582e-63	233.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_2120148_0	1089545.KB913037_gene479	1.394e-84	285.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DYVZ@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2120148_2	1382306.JNIM01000001_gene1359	9.585e-18	88.0	COG2802@1|root,COG2802@2|Bacteria,2G76N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase S16 lon domain protein	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
CMS3_k127_2122133_1	861299.J421_6273	3.574e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,1ZU2B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
CMS3_k127_2122133_2	1128421.JAGA01000001_gene2463	5.898e-22	104.0	COG5343@1|root,COG5343@2|Bacteria,2NR4V@2323|unclassified Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
CMS3_k127_2122133_0	1121930.AQXG01000016_gene1781	6.051e-54	208.0	COG2335@1|root,COG2335@2|Bacteria,4NQE5@976|Bacteroidetes	976|Bacteroidetes	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2124473_0	926569.ANT_04370	2.959e-185	586.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS3_k127_2124473_1	216594.MMAR_3393	2.255e-18	92.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,2374J@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	pmtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2125856_0	926550.CLDAP_25740	3.601e-305	950.0	COG5322@1|root,COG5322@2|Bacteria,2G7SR@200795|Chloroflexi	200795|Chloroflexi	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2126651_5	1128421.JAGA01000003_gene3422	9.067e-69	239.0	COG5553@1|root,COG5553@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
CMS3_k127_2126651_6	44251.PDUR_22820	2.217e-39	158.0	COG4223@1|root,COG4223@2|Bacteria,1TSFB@1239|Firmicutes,4I7PP@91061|Bacilli,26X59@186822|Paenibacillaceae	91061|Bacilli	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2126651_4	324602.Caur_3156	3.791e-73	258.0	COG2819@1|root,COG2819@2|Bacteria,2GAH9@200795|Chloroflexi,3764V@32061|Chloroflexia	32061|Chloroflexia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_2126651_8	316274.Haur_4171	1.933e-16	85.0	COG4283@1|root,COG4283@2|Bacteria,2G9ST@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
CMS3_k127_2126651_1	649638.Trad_0272	5.62e-133	437.0	COG2309@1|root,COG2309@2|Bacteria,1WI5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_2126651_9	926550.CLDAP_24490	1.964e-09	62.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS3_k127_2126651_3	1454004.AW11_00001	8.149e-86	291.0	28JYD@1|root,2Z9NN@2|Bacteria,1MV9T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2126651_0	525904.Tter_0081	9.111e-244	773.0	COG3808@1|root,COG3808@2|Bacteria,2NNK9@2323|unclassified Bacteria	2|Bacteria	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS3_k127_2126651_7	1242864.D187_009672	9.723e-35	146.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria	1224|Proteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_2126651_2	156889.Mmc1_0146	2.608e-119	390.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polyphosphate kinase	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
CMS3_k127_2127329_0	926550.CLDAP_09520	4.404e-313	971.0	COG1472@1|root,COG1472@2|Bacteria,2G5S5@200795|Chloroflexi	200795|Chloroflexi	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS3_k127_2127329_1	937777.Deipe_0135	3.937e-41	152.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria,1WICF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
CMS3_k127_2133584_0	926550.CLDAP_27990	4.344e-135	440.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_2133584_1	357804.Ping_2596	5.378e-83	279.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RSKJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_2134141_1	1226325.HMPREF1548_00221	8.596e-14	78.0	COG4409@1|root,COG4409@2|Bacteria,1V5Q1@1239|Firmicutes,24FGZ@186801|Clostridia,36W5Z@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
CMS3_k127_2135488_5	1278073.MYSTI_01296	8.464e-100	331.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS3_k127_2135488_8	926569.ANT_18000	4.315e-23	101.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS3_k127_2135488_6	926569.ANT_17990	1.014e-45	173.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_2135488_4	926569.ANT_17980	1.661e-115	376.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS3_k127_2135488_0	525904.Tter_1698	6.47e-231	722.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS3_k127_2135488_3	1382356.JQMP01000003_gene2453	3.434e-117	391.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS3_k127_2135488_2	926550.CLDAP_18370	3.714e-138	445.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS3_k127_2135488_1	926550.CLDAP_20370	1.343e-172	550.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS3_k127_2135488_7	926569.ANT_17930	8.352e-38	145.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS3_k127_2135488_9	886293.Sinac_5289	6.051e-09	59.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
CMS3_k127_2138578_0	323261.Noc_1859	3.435e-50	193.0	2B0Q2@1|root,31T1Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2146821_1	365044.Pnap_1257	6.051e-12	77.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2146821_0	395494.Galf_2722	1.612e-29	130.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2146821_2	1123256.KB907926_gene987	4.485e-08	64.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1X3GA@135614|Xanthomonadales	135614|Xanthomonadales	P	Heavy metal translocating P-type atpase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
CMS3_k127_2148258_6	767817.Desgi_1265	6.785e-16	83.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2148258_1	485913.Krac_5027	1.128e-98	354.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_2148258_9	1452718.JBOY01000028_gene164	5.258e-10	73.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,1RN29@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_2148258_5	1128421.JAGA01000004_gene2679	6.734e-32	129.0	COG5485@1|root,COG5485@2|Bacteria,2NRTW@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_2148258_8	1121924.ATWH01000006_gene1962	2.516e-13	74.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4FMGJ@85023|Microbacteriaceae	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
CMS3_k127_2148258_2	396014.BF93_07905	2.42e-77	265.0	COG0745@1|root,COG0745@2|Bacteria,2H3IN@201174|Actinobacteria,4FCH7@85020|Dermabacteraceae	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2148258_4	590998.Celf_0793	9.206e-42	165.0	COG0642@1|root,COG2205@2|Bacteria,2IIK0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_2148258_0	1304284.L21TH_0766	3.575e-101	337.0	COG3153@1|root,COG3153@2|Bacteria,1V3TY@1239|Firmicutes,25DB3@186801|Clostridia,36U94@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2148258_10	635013.TherJR_1787	5.474e-08	59.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_2148258_7	1122194.AUHU01000014_gene1129	3.924e-14	84.0	COG3507@1|root,COG3509@1|root,COG3507@2|Bacteria,COG3509@2|Bacteria,1R4H2@1224|Proteobacteria,1SXV5@1236|Gammaproteobacteria,469KM@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Ricin-type beta-trefoil	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	RicinB_lectin_2
CMS3_k127_2148258_3	926569.ANT_28790	5.458e-49	178.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS3_k127_2162586_1	926560.KE387027_gene1062	5.1e-74	255.0	COG1132@1|root,COG1132@2|Bacteria,1WKZ0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_2162586_0	292459.STH1427	1.458e-116	398.0	COG1132@1|root,COG1132@2|Bacteria,1UZA0@1239|Firmicutes,24DXZ@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_2162917_4	326427.Cagg_2198	5.216e-48	192.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
CMS3_k127_2162917_0	1449976.KALB_2459	4.305e-105	349.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,4DXBN@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2162917_3	1132509.C447_08158	1.674e-61	221.0	COG0842@1|root,arCOG01463@2157|Archaea	2157|Archaea	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CMS3_k127_2162917_1	479434.Sthe_1551	2.356e-79	281.0	COG4585@1|root,COG4585@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
CMS3_k127_2162917_2	1449976.KALB_2456	7.819e-77	263.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4DXC6@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2170561_7	118166.JH976538_gene5251	1.19e-14	84.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_2170561_4	326427.Cagg_3284	3.693e-27	128.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
CMS3_k127_2170561_8	324602.Caur_0300	1.649e-07	59.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2170561_6	192952.MM_2246	2.363e-15	83.0	COG0640@1|root,arCOG01681@2157|Archaea,2XYSN@28890|Euryarchaeota,2NBKM@224756|Methanomicrobia	224756|Methanomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS3_k127_2170561_0	552396.HMPREF0863_01829	1.342e-88	305.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,3VQ5H@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2170561_2	479434.Sthe_0586	3.76e-47	190.0	COG3266@1|root,COG3266@2|Bacteria,2GBHM@200795|Chloroflexi,27Y68@189775|Thermomicrobia	189775|Thermomicrobia	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_2170561_5	118168.MC7420_1733	1.553e-25	114.0	COG1357@1|root,COG1357@2|Bacteria,1G37B@1117|Cyanobacteria,1HAA6@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_2170561_1	926550.CLDAP_15070	4.661e-68	240.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	M1-693	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
CMS3_k127_2170561_3	706587.Desti_2879	1.099e-27	120.0	2E631@1|root,330S3@2|Bacteria,1NJ41@1224|Proteobacteria,430SA@68525|delta/epsilon subdivisions,2WVRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2174022_3	243275.TDE_1738	2.213e-07	62.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2J7KD@203691|Spirochaetes	203691|Spirochaetes	M	M23 M37 peptidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
CMS3_k127_2174022_2	1173026.Glo7428_0228	7.969e-42	165.0	2AWP9@1|root,31NK6@2|Bacteria,1G6HF@1117|Cyanobacteria	1117|Cyanobacteria	S	Galactose-3-O-sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Gal-3-0_sulfotr,Sulfotransfer_2
CMS3_k127_2174022_1	926549.KI421517_gene1991	3.588e-137	448.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,47JCC@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS3_k127_2174022_0	1089550.ATTH01000001_gene219	2.139e-246	775.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,1FJGH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Adenylylsulphate kinase	cysN	GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
CMS3_k127_2174022_4	1278073.MYSTI_07843	1.587e-05	55.0	COG2204@1|root,COG3292@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2YUEQ@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS3_k127_2186514_1	644966.Tmar_0336	2.197e-35	145.0	COG0500@1|root,COG1547@1|root,COG1547@2|Bacteria,COG2226@2|Bacteria,1V45D@1239|Firmicutes	1239|Firmicutes	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_2186514_0	1121439.dsat_0582	1.507e-124	421.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2M9JU@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS3_k127_2186567_1	765420.OSCT_0641	1.273e-31	134.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
CMS3_k127_2186567_3	1380386.JIAW01000014_gene2784	1.113e-11	70.0	297QE@1|root,2ZUXA@2|Bacteria,2IGMJ@201174|Actinobacteria,23A48@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2186567_0	751944.HALDL1_10215	1.137e-61	224.0	COG0702@1|root,arCOG03015@2157|Archaea,2XVBX@28890|Euryarchaeota,23U9C@183963|Halobacteria	183963|Halobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS3_k127_2186567_2	1120999.JONM01000001_gene1189	4.923e-16	86.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Pectate_lyase_3
CMS3_k127_2187452_1	1254432.SCE1572_39530	2.667e-14	84.0	COG3173@1|root,COG3173@2|Bacteria,1R5VZ@1224|Proteobacteria	1224|Proteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
CMS3_k127_2187452_0	1144275.COCOR_01875	1.761e-18	102.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS3_k127_2187512_0	1040986.ATYO01000002_gene4296	3.681e-21	98.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UDVU@28211|Alphaproteobacteria,43K7B@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_2187512_3	326427.Cagg_1566	2.147e-10	65.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	mrx1	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
CMS3_k127_2187512_2	1128421.JAGA01000002_gene1331	2.174e-13	75.0	2ED7R@1|root,3374C@2|Bacteria,2NS2D@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2187512_1	479435.Kfla_2481	8.351e-20	90.0	COG3342@1|root,COG3342@2|Bacteria,2HWBG@201174|Actinobacteria,4DQU9@85009|Propionibacteriales	201174|Actinobacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
CMS3_k127_2192718_1	306281.AJLK01000101_gene3315	1.999e-05	53.0	2E1PV@1|root,32X09@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2192718_0	1499967.BAYZ01000009_gene5353	4.342e-72	254.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
CMS3_k127_2192749_0	882.DVU_1023	1.801e-34	144.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2M9SU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Rhomboid family protein	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
CMS3_k127_2192749_1	383372.Rcas_1639	7.591e-07	59.0	COG0457@1|root,COG0457@2|Bacteria,2GB8I@200795|Chloroflexi,377JS@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_220108_0	196162.Noca_3152	1.868e-48	183.0	COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4DPJS@85009|Propionibacteriales	201174|Actinobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS3_k127_2204657_0	926569.ANT_18650	4.27e-83	287.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_2204657_2	1382359.JIAL01000001_gene1268	6.16e-41	160.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS3_k127_2204657_1	335543.Sfum_1753	4.803e-47	189.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2MRB3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transport system involved in gliding motility auxiliary component-like	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_2213687_2	316274.Haur_1887	2.337e-100	337.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi,376UM@32061|Chloroflexia	32061|Chloroflexia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_2213687_1	211165.AJLN01000040_gene6449	3.158e-163	521.0	COG3185@1|root,COG3185@2|Bacteria,1G307@1117|Cyanobacteria,1JKH1@1189|Stigonemataceae	1117|Cyanobacteria	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_4,Glyoxalase_5
CMS3_k127_2213687_0	118163.Ple7327_0419	1.028e-202	636.0	COG3508@1|root,COG3508@2|Bacteria,1G3C7@1117|Cyanobacteria,3VHP3@52604|Pleurocapsales	1117|Cyanobacteria	Q	PFAM Homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
CMS3_k127_2213687_6	1348114.OM33_02710	0.0003054	51.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,2Q039@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	QU	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS3_k127_2213687_4	56107.Cylst_4290	1.308e-34	136.0	COG4634@1|root,COG4634@2|Bacteria,1G7AE@1117|Cyanobacteria,1HPMX@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2213687_3	56110.Oscil6304_3177	6.379e-35	136.0	COG2442@1|root,COG2442@2|Bacteria,1G72R@1117|Cyanobacteria,1HCMC@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CMS3_k127_2213687_5	383372.Rcas_2484	2.78e-27	121.0	COG0477@1|root,COG2814@2|Bacteria,2G6MT@200795|Chloroflexi,375W2@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS3_k127_2218785_1	497964.CfE428DRAFT_1144	1.106e-15	86.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,46TZW@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Reg_prop,Y_Y_Y
CMS3_k127_2218785_0	1173028.ANKO01000250_gene2370	3.503e-114	381.0	COG0477@1|root,COG2814@2|Bacteria,1GQ8C@1117|Cyanobacteria,1HH9P@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2224926_0	641526.ADIWIN_0977	1.727e-64	229.0	COG0500@1|root,COG2226@2|Bacteria,4NJH4@976|Bacteroidetes,1I1ND@117743|Flavobacteriia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_2227578_2	393595.ABO_0184	3.695e-29	119.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1XI7A@135619|Oceanospirillales	135619|Oceanospirillales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2227578_3	469383.Cwoe_2697	5.39e-11	71.0	COG1309@1|root,COG1309@2|Bacteria,2I8DJ@201174|Actinobacteria,4CSYG@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2227578_1	767817.Desgi_1135	3.212e-46	171.0	COG2030@1|root,COG2030@2|Bacteria,1VE44@1239|Firmicutes,24SWZ@186801|Clostridia	186801|Clostridia	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_2227578_0	767817.Desgi_1150	5.76e-78	268.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2231829_0	1173021.ALWA01000004_gene3249	8.548e-137	473.0	COG1198@1|root,COG1198@2|Bacteria,1G2IZ@1117|Cyanobacteria	1117|Cyanobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
CMS3_k127_2231829_4	211114.JOEF01000005_gene2107	2.946e-33	131.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria,4E5CC@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_2231829_3	1268072.PSAB_23540	2.053e-44	168.0	COG3832@1|root,COG3832@2|Bacteria,1V352@1239|Firmicutes,4HFYT@91061|Bacilli,276Z8@186822|Paenibacillaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_2231829_2	562970.Btus_1426	1.212e-47	195.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_2231829_1	1385515.N791_14130	2.311e-110	364.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X2XI@135614|Xanthomonadales	135614|Xanthomonadales	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2232273_0	1449126.JQKL01000089_gene486	1.844e-258	831.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia	186801|Clostridia	L	snf2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF3670,Helicase_C,SNF2_N,SWIM
CMS3_k127_2232273_1	765420.OSCT_0941	1.465e-60	220.0	COG4279@1|root,COG4279@2|Bacteria,2G7AI@200795|Chloroflexi	200795|Chloroflexi	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS3_k127_2232273_4	749414.SBI_08722	3.96e-20	92.0	COG2801@1|root,COG2801@2|Bacteria,2GN25@201174|Actinobacteria	201174|Actinobacteria	L	Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_32,rve,rve_3
CMS3_k127_2232273_5	1217720.ALOX01000022_gene3113	6.911e-17	84.0	COG3415@1|root,COG3415@2|Bacteria,1NV0F@1224|Proteobacteria,2URVM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,HTH_33
CMS3_k127_2232273_2	1476583.DEIPH_ctg020orf0027	2.057e-46	169.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_33
CMS3_k127_2232273_6	387093.SUN_0872	5.738e-14	73.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,42R7X@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
CMS3_k127_2232273_7	369723.Strop_1626	2.694e-09	66.0	COG3210@1|root,COG3210@2|Bacteria,2IJX4@201174|Actinobacteria	201174|Actinobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2233352_2	1128421.JAGA01000001_gene2382	2.549e-27	113.0	COG4992@1|root,COG4992@2|Bacteria,2NP0N@2323|unclassified Bacteria	2|Bacteria	E	acetylornithine and succinylornithine aminotransferase	lysJ	-	2.6.1.11,2.6.1.17	ko:K00821,ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Peptidase_M20
CMS3_k127_2233352_1	926554.KI912628_gene2723	8.749e-105	346.0	COG0548@1|root,COG0548@2|Bacteria,1WIHT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the acetylglutamate kinase family. LysZ subfamily	lysZ	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_2233352_0	326427.Cagg_3596	1.573e-138	449.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi,374YZ@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
CMS3_k127_2247639_1	485913.Krac_1006	1.793e-38	162.0	COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS3_k127_2247639_2	330214.NIDE3836	9.412e-30	128.0	COG2197@1|root,COG3290@1|root,COG2197@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	prhJ	-	-	ko:K06375	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	GerE,HATPase_c,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_2247639_0	484770.UFO1_1101	2.193e-98	352.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS3_k127_2253445_1	357808.RoseRS_1979	2.716e-121	400.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia	32061|Chloroflexia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS3_k127_2253445_3	314271.RB2654_06439	2.086e-66	251.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_2253445_4	243231.GSU2698	1.64e-38	151.0	COG1309@1|root,COG1309@2|Bacteria,1N0GT@1224|Proteobacteria,42RFI@68525|delta/epsilon subdivisions,2X5UB@28221|Deltaproteobacteria,43TM3@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Tetracycline repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_10,TetR_N
CMS3_k127_2253445_2	164757.Mjls_0587	2.386e-82	284.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,233HK@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2253445_0	1313172.YM304_41740	3.577e-161	522.0	COG0477@1|root,COG2814@2|Bacteria,2I2DZ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_2253445_5	1313172.YM304_41730	6.241e-32	136.0	2DQVM@1|root,338Y0@2|Bacteria	2|Bacteria	S	lipid binding	lprG	GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008289,GO:0009405,GO:0009605,GO:0009607,GO:0009966,GO:0010469,GO:0010646,GO:0016020,GO:0020012,GO:0023051,GO:0030312,GO:0030545,GO:0030682,GO:0031982,GO:0035091,GO:0042783,GO:0042785,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043230,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051812,GO:0051832,GO:0051834,GO:0051861,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065009,GO:0071944,GO:0075136,GO:0097367,GO:0097691,GO:0098772,GO:1903561	-	ko:K14954,ko:K14955	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	LppX_LprAFG
CMS3_k127_2253445_6	28583.AMAG_17420T0	1.817e-05	49.0	COG0694@1|root,KOG2358@2759|Eukaryota,38H60@33154|Opisthokonta,3NYHI@4751|Fungi	4751|Fungi	O	hira-interacting protein 5	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0031974,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051604,GO:0070013,GO:0071704,GO:0097428,GO:0106035,GO:1901564	-	ko:K22074	-	-	-	-	ko00000,ko03029	-	-	-	Nfu_N,NifU
CMS3_k127_2253498_1	326427.Cagg_3408	1.293e-05	56.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeY	-	-	ko:K05385	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	CHAT,DUF1822,HEAT_2,Lipase_GDSL_2,Vitellogenin_N
CMS3_k127_2253498_0	203119.Cthe_2171	7.175e-163	549.0	COG1061@1|root,COG1061@2|Bacteria,1TRA8@1239|Firmicutes,2481H@186801|Clostridia,3WNCQ@541000|Ruminococcaceae	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
CMS3_k127_2255752_1	530564.Psta_0806	9.153e-134	442.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
CMS3_k127_2255752_0	1123508.JH636440_gene2090	2.86e-239	754.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_2255752_4	1210884.HG799462_gene8487	7.956e-19	93.0	COG0517@1|root,COG0517@2|Bacteria,2J0FD@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_2255752_2	926569.ANT_18160	3.478e-51	190.0	COG2186@1|root,COG2186@2|Bacteria,2G8XU@200795|Chloroflexi	200795|Chloroflexi	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD
CMS3_k127_2255752_3	744980.TRICHSKD4_3186	8.127e-24	109.0	COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
CMS3_k127_2260692_2	32057.KB217478_gene250	3.304e-92	313.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	DUF938,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_2260692_6	1458357.BG58_00935	3.066e-45	177.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,1K0FT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_2260692_1	1144275.COCOR_02595	2.587e-111	380.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K16416	ko01052,map01052	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS3_k127_2260692_0	1133850.SHJG_1843	3.017e-173	554.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_2260692_4	1009370.ALO_01205	1.333e-63	234.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4H2TU@909932|Negativicutes	1239|Firmicutes	M	Monogalactosyldiacylglycerol synthase, C-terminal domain protein	ypfP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
CMS3_k127_2260692_3	861299.J421_6050	1.598e-72	251.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_6050|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2260692_7	251221.35214848	4.934e-40	161.0	2EN5W@1|root,33FTU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2260692_5	58344.JOEL01000002_gene1979	3.478e-52	194.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_25,PP-binding
CMS3_k127_2262746_1	224911.27349151	2.253e-56	208.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,3JS80@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Alpha-amylase domain	MA20_23410	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
CMS3_k127_2262746_0	926550.CLDAP_24640	2.111e-141	452.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi	200795|Chloroflexi	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
CMS3_k127_2262746_2	364733.XP_007803121.1	0.0001546	46.0	COG1501@1|root,KOG1066@2759|Eukaryota,39T0Y@33154|Opisthokonta,3NV6M@4751|Fungi,3QQSM@4890|Ascomycota,20FG0@147545|Eurotiomycetes,3MU7I@451870|Chaetothyriomycetidae	4751|Fungi	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_31
CMS3_k127_2263308_0	1173264.KI913949_gene1673	5.498e-118	398.0	COG0405@1|root,COG0405@2|Bacteria,1G20A@1117|Cyanobacteria,1H8BE@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_2270471_6	869210.Marky_0584	1.662e-27	127.0	COG4585@1|root,COG4585@2|Bacteria,1WIV0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_2270471_4	926569.ANT_00450	5.265e-52	188.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
CMS3_k127_2270471_1	1480694.DC28_06725	4.969e-124	408.0	COG0226@1|root,COG0226@2|Bacteria,2J9IU@203691|Spirochaetes	203691|Spirochaetes	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_2270471_3	316274.Haur_3998	2.67e-108	363.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi,375B0@32061|Chloroflexia	32061|Chloroflexia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS3_k127_2270471_0	316274.Haur_3999	1.211e-142	466.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi,374ZR@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS3_k127_2270471_2	765420.OSCT_1173	1.859e-118	385.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi,3751I@32061|Chloroflexia	32061|Chloroflexia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS3_k127_2270471_5	926569.ANT_27760	3.713e-48	181.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi	200795|Chloroflexi	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS3_k127_2279306_0	926569.ANT_17590	0.0	1171.0	COG3459@1|root,COG3459@2|Bacteria,2G9NQ@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2279306_1	1121438.JNJA01000001_gene2654	2.566e-31	125.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2M7XR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
CMS3_k127_2280292_2	298655.KI912266_gene2423	1.643e-08	65.0	2DRPS@1|root,33CHR@2|Bacteria,2GXSD@201174|Actinobacteria,4EX0H@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2280292_0	1273538.G159_14145	8.855e-93	315.0	COG0657@1|root,COG0657@2|Bacteria,1TRYT@1239|Firmicutes,4HC3I@91061|Bacilli,26F97@186818|Planococcaceae	91061|Bacilli	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_2280292_1	550540.Fbal_0070	6.248e-48	177.0	COG1670@1|root,COG1670@2|Bacteria,1RAMS@1224|Proteobacteria	1224|Proteobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
CMS3_k127_2280863_2	926569.ANT_19330	0.0007649	52.0	COG2133@1|root,COG2755@1|root,COG4961@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Lipase_GDSL_2,Malectin,TadE
CMS3_k127_2280863_0	518766.Rmar_1549	8.428e-268	841.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FIUV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	dehydrogenase, E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_2280863_1	1173027.Mic7113_1747	5.141e-235	756.0	COG1020@1|root,COG1020@2|Bacteria,1GBN8@1117|Cyanobacteria,1HH6H@1150|Oscillatoriales	1117|Cyanobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Condensation,KR,Nitroreductase,PP-binding
CMS3_k127_228197_1	926550.CLDAP_02060	1.349e-67	257.0	COG1807@1|root,COG1807@2|Bacteria,2G8SF@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_228197_3	383372.Rcas_0218	1.017e-55	210.0	COG0438@1|root,COG0438@2|Bacteria,2G6Z9@200795|Chloroflexi,3755I@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS3_k127_228197_0	1128421.JAGA01000002_gene1114	1.327e-113	380.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_228197_2	96561.Dole_3012	5.224e-62	221.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2MI8N@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_2290040_5	1235794.C811_02068	8.925e-25	108.0	COG3279@1|root,COG3279@2|Bacteria,2IPFZ@201174|Actinobacteria,4CYIJ@84998|Coriobacteriia	84998|Coriobacteriia	K	response regulator receiver	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
CMS3_k127_2290040_3	401526.TcarDRAFT_0220	4.374e-48	191.0	COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H1VW@909932|Negativicutes	909932|Negativicutes	T	5TM Receptors of the LytS-YhcK type, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase
CMS3_k127_2290040_6	1123269.NX02_11875	0.0002699	44.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K2F6@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve_3
CMS3_k127_2290040_0	926550.CLDAP_22540	1.004e-135	443.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS3_k127_2290040_4	102129.Lepto7375DRAFT_6895	7.495e-46	181.0	2E0AY@1|root,32VY9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2290040_2	485913.Krac_8232	1.593e-75	269.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2290040_1	383372.Rcas_4327	1.838e-130	449.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_229293_0	1242864.D187_001830	7.425e-188	625.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS3_k127_2293625_5	383372.Rcas_0492	2.468e-44	163.0	COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_2293625_3	211165.AJLN01000094_gene1160	4.13e-87	293.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.97	ko:K04477,ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
CMS3_k127_2293625_2	211165.AJLN01000094_gene1159	4.417e-132	430.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
CMS3_k127_2293625_6	694430.Natoc_3298	5.567e-25	117.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,23STH@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_2293625_1	324602.Caur_0946	3.827e-179	568.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi,3765I@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_2293625_0	324602.Caur_0945	5.426e-225	715.0	COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi,376PG@32061|Chloroflexia	32061|Chloroflexia	GM	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CMS3_k127_2293625_4	671143.DAMO_0205	3.35e-68	247.0	COG0438@1|root,COG0438@2|Bacteria,2NQUA@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_2293625_7	159087.Daro_2446	2.922e-06	59.0	28JAH@1|root,2Z95A@2|Bacteria,1MXKT@1224|Proteobacteria,2VI69@28216|Betaproteobacteria,2KW88@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS3_k127_2297360_1	926550.CLDAP_22240	3.173e-62	220.0	COG1215@1|root,COG1215@2|Bacteria,2G952@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,T2SSE_N
CMS3_k127_2297360_4	479434.Sthe_0412	2.623e-20	94.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
CMS3_k127_2297360_0	596152.DesU5LDRAFT_1410	4.305e-105	379.0	COG1352@1|root,COG5002@1|root,COG1352@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
CMS3_k127_2297360_6	1202768.JROF01000005_gene2336	9.192e-09	57.0	arCOG02329@1|root,arCOG06796@1|root,arCOG07605@1|root,arCOG02329@2157|Archaea,arCOG06796@2157|Archaea,arCOG07605@2157|Archaea,2Y5ZU@28890|Euryarchaeota	28890|Euryarchaeota	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
CMS3_k127_2297360_7	1056820.KB900696_gene4037	5.936e-05	47.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2PN7T@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	barA	GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,HAMP,HATPase_c,HisKA,Hpt,Response_reg
CMS3_k127_2297360_5	666685.R2APBS1_3244	8.809e-14	74.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG4257@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,COG4257@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1X4Y5@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS3_k127_2297360_3	880072.Desac_0096	2.069e-33	138.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_2297360_2	926550.CLDAP_19470	4.807e-39	167.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_230127_2	554065.XP_005847319.1	3.236e-14	77.0	KOG3762@1|root,KOG3762@2759|Eukaryota,37WK7@33090|Viridiplantae,34IB3@3041|Chlorophyta	3041|Chlorophyta	S	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1_like
CMS3_k127_230127_0	867845.KI911784_gene2466	1.874e-183	594.0	COG4770@1|root,COG4770@2|Bacteria,2GBIE@200795|Chloroflexi,374S0@32061|Chloroflexia	32061|Chloroflexia	I	Carbamoyl-phosphate synthetase large chain domain protein	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_230127_1	316274.Haur_4761	2.596e-41	153.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi,376RG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2301915_2	1210884.HG799475_gene15275	2.637e-07	65.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	colA	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	F5_F8_type_C,Glyco_hydro_cc,PKD,PPC,Peptidase_M9,Peptidase_M9_N
CMS3_k127_2301915_1	926569.ANT_08030	2.253e-22	115.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_2301915_0	1123277.KB893197_gene6105	9.494e-164	559.0	COG1520@1|root,COG3266@1|root,COG1520@2|Bacteria,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,47QPM@768503|Cytophagia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_2302728_0	316274.Haur_0023	2.014e-93	316.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2303986_1	269797.Mbar_A3399	1.489e-44	183.0	COG5276@1|root,arCOG02565@2157|Archaea,2Y1HK@28890|Euryarchaeota,2NA4J@224756|Methanomicrobia	224756|Methanomicrobia	S	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CMS3_k127_2303986_0	926550.CLDAP_03560	3.198e-72	251.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_2306184_1	1123276.KB893258_gene2948	1.752e-26	123.0	COG1835@1|root,COG1835@2|Bacteria,4NPVJ@976|Bacteroidetes,47PYS@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS3_k127_2306184_0	335543.Sfum_0701	3.749e-46	168.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2MR99@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS3_k127_2307960_1	926550.CLDAP_34690	3.622e-106	355.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_2307960_4	1000565.METUNv1_01440	1.111e-34	144.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
CMS3_k127_2307960_3	1073999.BN137_217	2.918e-45	174.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Inositol monophosphatase	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2538,iPC815.YPO2899	Inositol_P
CMS3_k127_2307960_0	926550.CLDAP_35600	3.069e-198	631.0	COG1653@1|root,COG1653@2|Bacteria,2G8XC@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG1653 ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS3_k127_2307960_2	926550.CLDAP_35610	2.333e-74	251.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	malF	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS3_k127_2310887_0	926569.ANT_25700	9.828e-41	170.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_2311129_2	1122915.AUGY01000011_gene3989	3.64e-22	101.0	2EGE1@1|root,33A5Y@2|Bacteria,1VV4C@1239|Firmicutes,4HVGE@91061|Bacilli,26YKG@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2311129_1	1122927.KB895414_gene5100	1.111e-23	103.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HWXY@91061|Bacilli,2704G@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
CMS3_k127_2311129_0	574375.BAGA_10105	2.815e-117	385.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_2312748_6	446462.Amir_2421	1.591e-07	64.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,2I8F1@201174|Actinobacteria,4DZF8@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_2312748_5	926569.ANT_15080	7.593e-24	117.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
CMS3_k127_2312748_8	981383.AEWH01000024_gene2666	4.384e-05	55.0	COG0454@1|root,COG0456@2|Bacteria,1V3NF@1239|Firmicutes,4HH7Y@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS3_k127_2312748_2	1121924.ATWH01000001_gene4463	9.683e-36	146.0	COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria,4FREE@85023|Microbacteriaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2312748_3	485913.Krac_0393	9.97e-33	139.0	COG1266@1|root,COG1266@2|Bacteria,2G772@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2312748_4	189753.AXAS01000017_gene3061	2.586e-26	113.0	COG1622@1|root,COG2132@1|root,COG3474@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,COG3474@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria,3JV1C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C
CMS3_k127_2312748_7	1123073.KB899241_gene2311	4.615e-07	59.0	2DWEZ@1|root,33ZZS@2|Bacteria,1NYBC@1224|Proteobacteria,1SQSQ@1236|Gammaproteobacteria,1XAUU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2312748_1	1128421.JAGA01000003_gene3678	2.863e-97	349.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS3_k127_2312748_0	1282876.BAOK01000001_gene2118	0.0	1057.0	COG0439@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	carbamoyl-phosphate synthase	MA20_04765	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
CMS3_k127_2321459_0	479434.Sthe_0227	3.056e-237	767.0	COG0587@1|root,COG0587@2|Bacteria,2G811@200795|Chloroflexi,27Z3J@189775|Thermomicrobia	189775|Thermomicrobia	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
CMS3_k127_2321459_2	1273538.G159_04940	1.874e-12	71.0	2DNVA@1|root,32ZBE@2|Bacteria,1W480@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2321459_1	42256.RradSPS_0358	2.375e-66	248.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_2321650_4	706587.Desti_0743	6.948e-08	54.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_2321650_0	1197130.BAFM01000016_gene2564	8.012e-87	299.0	COG0438@1|root,arCOG01407@2157|Archaea,2Y8BB@28890|Euryarchaeota,24180@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2321650_1	926550.CLDAP_30030	8.861e-70	247.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	-	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
CMS3_k127_2321650_3	1229909.NSED_02405	3.846e-12	80.0	COG3391@1|root,arCOG03563@2157|Archaea	2157|Archaea	P	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,NHL,PKD
CMS3_k127_2321650_5	926569.ANT_12980	4.496e-05	56.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
CMS3_k127_2321650_2	926550.CLDAP_07570	2.21e-45	173.0	COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_2322920_4	1267535.KB906767_gene482	8.245e-52	187.0	COG0640@1|root,COG0640@2|Bacteria,3Y4ZD@57723|Acidobacteria,2JMYS@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS3_k127_2322920_5	1128421.JAGA01000002_gene1136	6.476e-49	179.0	COG5646@1|root,COG5646@2|Bacteria,2NQX2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS3_k127_2322920_3	525904.Tter_2348	1.055e-53	199.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	nicD	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248	3.5.1.106	ko:K15357,ko:K19311	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_2322920_2	96561.Dole_0790	7.503e-68	263.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria,2MNQR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
CMS3_k127_2322920_8	446470.Snas_6020	5.933e-41	175.0	2E809@1|root,332EJ@2|Bacteria,2H3RK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2322920_0	1033734.CAET01000038_gene202	1.75e-84	283.0	COG4430@1|root,COG4430@2|Bacteria,1UYP9@1239|Firmicutes,4HDZD@91061|Bacilli,1ZDB7@1386|Bacillus	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	ydeI	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
CMS3_k127_2322920_1	937777.Deipe_2380	7.683e-82	282.0	COG0679@1|root,COG0679@2|Bacteria,1WIWK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS3_k127_2322920_7	1429046.RR21198_0066	1.099e-46	184.0	COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4FYI5@85025|Nocardiaceae	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS3_k127_2322920_6	1169144.KB910936_gene1240	3.622e-47	193.0	COG0823@1|root,COG0823@2|Bacteria,1UG1S@1239|Firmicutes,4IJ8R@91061|Bacilli,1ZMUJ@1386|Bacillus	91061|Bacilli	U	Phospholipase C, catalytic domain (part); domain X	-	-	4.6.1.13	ko:K01771	ko00562,map00562	-	R03332	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PI-PLC-X
CMS3_k127_2322920_9	1184609.KILIM_001_00420	0.0005626	53.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4F7CZ@85018|Dermatophilaceae	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
CMS3_k127_2323549_1	485913.Krac_4382	4.12e-28	118.0	COG1670@1|root,COG1670@2|Bacteria,2G9C1@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_2323549_0	1121382.JQKG01000005_gene3282	1.935e-103	357.0	COG0249@1|root,COG0249@2|Bacteria,1WJFP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
CMS3_k127_2325726_1	926550.CLDAP_33530	2.149e-76	261.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS3_k127_2325726_0	1499967.BAYZ01000025_gene285	1.426e-227	719.0	COG0018@1|root,COG0018@2|Bacteria,2NP0H@2323|unclassified Bacteria	2|Bacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iECABU_c1320.ECABU_c21380,iECNA114_1301.ECNA114_1940,iECSE_1348.ECSE_2111,iECSF_1327.ECSF_1736,iEcolC_1368.EcolC_1756,iJN746.PP_5089,iLF82_1304.LF82_0128,iNRG857_1313.NRG857_09405,iUMNK88_1353.UMNK88_2348,ic_1306.c2291	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS3_k127_2325726_3	1122223.KB890697_gene1172	1.945e-25	116.0	COG2267@1|root,COG2267@2|Bacteria,1WN05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_2325726_4	497964.CfE428DRAFT_1140	3.233e-12	75.0	COG1611@1|root,COG1611@2|Bacteria,46SEG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Possible lysine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
CMS3_k127_2325726_2	926550.CLDAP_05580	1.225e-56	207.0	COG1608@1|root,COG1608@2|Bacteria,2G6TH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aspartate glutamate uridylate kinase	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_2325726_5	177437.HRM2_22860	0.0006466	48.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2WJR5@28221|Deltaproteobacteria,2MIAJ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	LysM,MS_channel,TM_helix
CMS3_k127_2328377_1	552811.Dehly_1516	3.467e-71	250.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi	200795|Chloroflexi	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_2328377_2	485913.Krac_2087	2.17e-38	153.0	COG0491@1|root,COG0491@2|Bacteria,2G78X@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_2328377_0	626887.J057_17800	5.024e-87	297.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,1RS3G@1236|Gammaproteobacteria,466BV@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	atuB	-	-	ko:K13774	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short_C2
CMS3_k127_2328377_3	880073.Calab_2556	1.048e-32	130.0	COG3251@1|root,COG3251@2|Bacteria,2NRE2@2323|unclassified Bacteria	2|Bacteria	S	MbtH-like protein	-	-	-	ko:K05375,ko:K09190	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH,YqcI_YcgG
CMS3_k127_2341259_1	926550.CLDAP_05310	2.034e-78	273.0	COG1319@1|root,COG1319@2|Bacteria,2G8QC@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_2341259_0	926569.ANT_14810	6.592e-263	833.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS3_k127_2344547_1	1526927.Plano_0099	2.533e-50	186.0	COG2114@1|root,COG2114@2|Bacteria,1V8X9@1239|Firmicutes,4IQCE@91061|Bacilli,26GPU@186818|Planococcaceae	91061|Bacilli	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_2344547_0	502025.Hoch_6072	1.254e-120	400.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2YZWP@29|Myxococcales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS3_k127_2346099_4	1196323.ALKF01000188_gene4808	0.0001618	50.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HBDU@91061|Bacilli,26SMM@186822|Paenibacillaceae	91061|Bacilli	M	Mechanosensitive ion channel	yhdY	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS3_k127_2346099_0	349521.HCH_02186	8.58e-176	559.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RV50@1236|Gammaproteobacteria,1XIHU@135619|Oceanospirillales	135619|Oceanospirillales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_2346099_1	1382306.JNIM01000001_gene3887	8.894e-102	338.0	COG1028@1|root,COG1028@2|Bacteria	1382306.JNIM01000001_gene3887|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2346099_3	710686.Mycsm_04998	1.224e-46	175.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,238YW@1762|Mycobacteriaceae	201174|Actinobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
CMS3_k127_2346099_2	604331.AUHY01000065_gene1068	3.827e-51	184.0	COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
CMS3_k127_2349118_0	926569.ANT_12990	5.57e-33	145.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
CMS3_k127_2349118_2	219305.MCAG_03096	2.957e-17	96.0	COG0501@1|root,COG0501@2|Bacteria,2GZ0N@201174|Actinobacteria,4DJKN@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_2349118_3	1172188.KB911820_gene2155	8.929e-13	75.0	2B2RZ@1|root,31VC7@2|Bacteria,2GVDD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349118_1	1323361.JPOC01000069_gene1431	9.82e-24	104.0	COG0119@1|root,COG0119@2|Bacteria,2GKTP@201174|Actinobacteria,4FUUW@85025|Nocardiaceae	201174|Actinobacteria	E	Hydroxymethylglutaryl-CoA lyase	-	-	4.1.3.4,4.1.3.46	ko:K01640,ko:K18314	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090,R10674	RC00502,RC00503,RC01118,RC01205,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_2349522_6	1206735.BAGG01000061_gene2606	1.74e-11	64.0	COG5113@1|root,COG3236@2|Bacteria,2HQRT@201174|Actinobacteria,4G1VN@85025|Nocardiaceae	201174|Actinobacteria	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
CMS3_k127_2349522_7	498211.CJA_3047	0.0001137	51.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria	1224|Proteobacteria	U	Rhs Element Vgr Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349522_1	99598.Cal7507_2519	6.259e-88	311.0	COG2931@1|root,COG3211@1|root,COG4222@1|root,COG2931@2|Bacteria,COG3211@2|Bacteria,COG4222@2|Bacteria,1GQ3P@1117|Cyanobacteria,1HJ47@1161|Nostocales	1117|Cyanobacteria	Q	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Alk_phosphatase,Exo_endo_phos,GDPD,HemolysinCabind,Phytase-like
CMS3_k127_2349522_0	1121930.AQXG01000002_gene2358	4.868e-154	492.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,1IPAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_2349522_2	641524.ADICYQ_4098	6.86e-85	287.0	2C3PP@1|root,2Z954@2|Bacteria,4NIZX@976|Bacteroidetes,47V30@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349522_4	926550.CLDAP_20280	1.123e-70	249.0	COG1940@1|root,COG1940@2|Bacteria,2G7NH@200795|Chloroflexi	200795|Chloroflexi	GK	ROK family	ppgK	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_2349522_5	1245471.PCA10_04370	5.382e-25	111.0	COG0824@1|root,COG0824@2|Bacteria,1N8J9@1224|Proteobacteria,1TC08@1236|Gammaproteobacteria,1YJJV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS3_k127_2349522_3	926569.ANT_22870	2.599e-71	248.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS3_k127_2366870_1	383372.Rcas_3469	5.642e-107	355.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi,374VK@32061|Chloroflexia	32061|Chloroflexia	HJ	PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
CMS3_k127_2366870_11	867845.KI911784_gene2372	1.189e-14	77.0	2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi,37602@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
CMS3_k127_2366870_0	709986.Deima_1929	5.446e-116	386.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
CMS3_k127_2366870_5	1036674.A28LD_0168	1.627e-56	205.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,2QF3A@267893|Idiomarinaceae	1236|Gammaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_2366870_7	388739.RSK20926_13174	8.104e-49	177.0	COG0720@1|root,COG0720@2|Bacteria,1RD4G@1224|Proteobacteria,2U78V@28211|Alphaproteobacteria,2P34T@2433|Roseobacter	28211|Alphaproteobacteria	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_2366870_13	309801.trd_0743	0.0009658	51.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi,27XFD@189775|Thermomicrobia	189775|Thermomicrobia	M	Glutamine amidotransferase domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS3_k127_2366870_6	313628.LNTAR_04741	3.647e-53	196.0	COG0603@1|root,COG0603@2|Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS3_k127_2366870_9	1499683.CCFF01000014_gene3776	7.699e-20	102.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,36EQA@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CMS3_k127_2366870_10	765420.OSCT_2126	2.251e-17	92.0	2A540@1|root,30TSN@2|Bacteria,2G9TT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2366870_2	765420.OSCT_2127	6.454e-91	326.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2366870_8	118163.Ple7327_4428	1.253e-29	123.0	2BG65@1|root,32A2Y@2|Bacteria,1G6VZ@1117|Cyanobacteria,3VJZ3@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2366870_12	1122223.KB890697_gene1075	0.0001216	51.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Big_5,CHU_C,DUF642,Haemagg_act,SprB
CMS3_k127_2366870_3	926550.CLDAP_34110	5.491e-64	246.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_2366870_4	926550.CLDAP_34120	5.505e-59	221.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_2380012_0	639283.Snov_0497	1.86e-188	594.0	COG0687@1|root,COG0687@2|Bacteria,1NKD7@1224|Proteobacteria,2TYST@28211|Alphaproteobacteria,3F0UM@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
CMS3_k127_2381797_3	760568.Desku_0192	1.28e-60	219.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,260T4@186807|Peptococcaceae	186801|Clostridia	C	heterodisulfide reductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS3_k127_2381797_4	760568.Desku_0191	5.427e-40	155.0	COG1150@1|root,COG1150@2|Bacteria,1VTDZ@1239|Firmicutes,24XQE@186801|Clostridia,265EF@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17
CMS3_k127_2381797_0	1125863.JAFN01000001_gene2935	4.346e-144	477.0	COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
CMS3_k127_2381797_1	1125863.JAFN01000001_gene2931	1.884e-98	339.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Fer4_9,Nitrate_red_gam
CMS3_k127_2381797_2	429009.Adeg_1333	3.777e-78	269.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,42FM3@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
CMS3_k127_2388409_0	926569.ANT_04250	1.654e-238	749.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi	200795|Chloroflexi	K	PBP superfamily domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	HTH_3,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
CMS3_k127_2388409_2	1123278.KB893533_gene158	3.446e-16	85.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NJ2Y@976|Bacteroidetes,47N0D@768503|Cytophagia	976|Bacteroidetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,HisKA_2,Reg_prop,Response_reg,Y_Y_Y
CMS3_k127_2388409_1	1223410.KN050846_gene1586	2.153e-166	535.0	COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia	976|Bacteroidetes	L	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
CMS3_k127_2396295_4	670487.Ocepr_0191	5.33e-15	76.0	COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria	2|Bacteria	P	domain protein	yjbQ	-	-	ko:K03455,ko:K03499	-	-	-	-	ko00000,ko02000	2.A.37,2.A.38.1,2.A.38.4	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS3_k127_2396295_1	869210.Marky_1959	2.283e-92	314.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
CMS3_k127_2396295_2	1303518.CCALI_01047	2.266e-66	235.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_2396295_3	1541065.JRFE01000006_gene4877	3.155e-45	177.0	COG5607@1|root,COG5607@2|Bacteria,1G6JV@1117|Cyanobacteria	1117|Cyanobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
CMS3_k127_2396295_0	1128421.JAGA01000004_gene2620	2.629e-136	444.0	COG1960@1|root,COG1960@2|Bacteria,2NQE6@2323|unclassified Bacteria	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2396295_5	745310.G432_10790	0.0007057	48.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,2K0HU@204457|Sphingomonadales	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,Acyltransferase,PP-binding,Thioesterase
CMS3_k127_2406112_0	357808.RoseRS_2190	8.256e-84	302.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
CMS3_k127_2419143_1	316274.Haur_3716	4.947e-107	357.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2419143_2	479434.Sthe_3164	3.045e-90	305.0	COG1595@1|root,COG3631@1|root,COG1595@2|Bacteria,COG3631@2|Bacteria,2G7NX@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2419143_0	395495.Lcho_4209	5.446e-119	390.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,2VPK0@28216|Betaproteobacteria,1KM9A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
CMS3_k127_2431835_2	316274.Haur_4394	8.792e-114	375.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
CMS3_k127_2431835_4	1128421.JAGA01000003_gene3632	1.867e-86	292.0	COG1028@1|root,COG1028@2|Bacteria	1128421.JAGA01000003_gene3632|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2431835_0	926550.CLDAP_39110	8.032e-154	496.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2431835_1	316274.Haur_0959	6.413e-132	430.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2431835_3	1128421.JAGA01000003_gene3642	2.528e-96	323.0	COG0294@1|root,COG0294@2|Bacteria,2NNN7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
CMS3_k127_2431835_5	313624.NSP_8140	7.413e-13	77.0	COG1309@1|root,COG1309@2|Bacteria,1G1RF@1117|Cyanobacteria,1HIID@1161|Nostocales	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_2431948_0	926550.CLDAP_32460	8.704e-73	273.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2431948_1	234267.Acid_1421	4.024e-49	196.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_2431948_2	314345.SPV1_12295	0.0001107	49.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS3_k127_243297_2	1278073.MYSTI_05982	6.555e-23	113.0	COG3227@1|root,COG3591@1|root,COG3227@2|Bacteria,COG3591@2|Bacteria,1QXPY@1224|Proteobacteria,43E6J@68525|delta/epsilon subdivisions,2X7H9@28221|Deltaproteobacteria,2Z3GG@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M36
CMS3_k127_243297_1	1123261.AXDW01000017_gene3177	2.809e-34	149.0	COG5276@1|root,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria	1224|Proteobacteria	N	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,He_PIG,LVIVD
CMS3_k127_243297_0	926550.CLDAP_37650	4.115e-97	324.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_2448638_2	926569.ANT_13360	4.913e-38	149.0	COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_2448638_0	926569.ANT_13370	6.064e-167	535.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS3_k127_2448638_1	309799.DICTH_1686	5.996e-127	421.0	COG0469@1|root,COG0469@2|Bacteria	2|Bacteria	G	pyruvate kinase activity	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40,2.7.7.4	ko:K00873,ko:K00958	ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050,M00176,M00596	R00200,R00430,R00529,R01138,R01858,R02320,R04929	RC00002,RC00015,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iECO103_1326.ECO103_1819,iPC815.YPO2393	PEP-utilizers,PK,PK_C
CMS3_k127_2448705_0	1487953.JMKF01000006_gene5813	0.0	1229.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H9JF@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS3_k127_2448705_1	644282.Deba_1148	7.006e-127	420.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS3_k127_2456954_2	574375.BAGA_11900	3.876e-43	169.0	COG1670@1|root,COG1670@2|Bacteria,1VVI3@1239|Firmicutes	1239|Firmicutes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2456954_4	1045004.OKIT_1404	1.132e-05	51.0	COG1434@1|root,COG1434@2|Bacteria,1V973@1239|Firmicutes,4HJHS@91061|Bacilli	91061|Bacilli	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS3_k127_2456954_1	324602.Caur_0649	2.18e-54	202.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_2456954_0	1528106.JRJE01000031_gene3231	2.708e-90	316.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,2TQY1@28211|Alphaproteobacteria,2JT22@204441|Rhodospirillales	204441|Rhodospirillales	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
CMS3_k127_2456954_3	56107.Cylst_0009	3.324e-16	93.0	COG1020@1|root,COG1020@2|Bacteria,1G2QF@1117|Cyanobacteria,1HIRK@1161|Nostocales	1117|Cyanobacteria	Q	protein containing a NRPS condensation (Elongation) domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
CMS3_k127_2457521_1	1131814.JAFO01000001_gene4403	8.051e-79	280.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2457521_0	264732.Moth_1737	2.215e-87	298.0	COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,25E75@186801|Clostridia,42G63@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
CMS3_k127_2465788_1	926569.ANT_20130	7.246e-29	128.0	COG4409@1|root,COG4409@2|Bacteria,2G76D@200795|Chloroflexi	200795|Chloroflexi	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_2465788_0	1123023.JIAI01000012_gene9053	5.493e-32	141.0	COG0438@1|root,COG0438@2|Bacteria,2GN28@201174|Actinobacteria,4E1U2@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2465788_2	349124.Hhal_2363	2.317e-12	70.0	COG0438@1|root,COG0438@2|Bacteria,1PDW1@1224|Proteobacteria,1RZIK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsular polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_2468353_1	33876.JNXY01000023_gene5157	4.501e-10	72.0	COG0265@1|root,COG2319@1|root,COG0265@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,TIR_2,Trypsin_2,WD40
CMS3_k127_2468353_0	1121377.KB906404_gene2878	2.399e-31	141.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS3_k127_2469453_1	1348663.KCH_37230	2.749e-24	111.0	COG3675@1|root,COG3675@2|Bacteria,2GND0@201174|Actinobacteria	201174|Actinobacteria	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CMS3_k127_2469453_0	1380390.JIAT01000009_gene711	5.48e-29	126.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,4CQR5@84995|Rubrobacteria	84995|Rubrobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS3_k127_2474037_4	324602.Caur_1114	4.063e-41	171.0	COG1091@1|root,COG1091@2|Bacteria,2G9A2@200795|Chloroflexi,375MR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS3_k127_2474037_2	926569.ANT_22460	2.044e-59	213.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS3_k127_2474037_0	1173021.ALWA01000010_gene1403	3.368e-132	433.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_2474037_5	1122176.KB903541_gene262	1.97e-25	114.0	COG0296@1|root,COG3743@1|root,COG0296@2|Bacteria,COG3743@2|Bacteria,4NUCY@976|Bacteroidetes,1IYR1@117747|Sphingobacteriia	976|Bacteroidetes	G	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,DUF4332
CMS3_k127_2474037_6	1408422.JHYF01000016_gene19	1.129e-09	63.0	COG1694@1|root,COG1694@2|Bacteria,1W2IW@1239|Firmicutes,254MT@186801|Clostridia	186801|Clostridia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS3_k127_2474037_1	926569.ANT_22470	6.065e-61	218.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS3_k127_2474037_3	1128421.JAGA01000004_gene2494	3.111e-57	205.0	COG0315@1|root,COG0315@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS3_k127_2474037_7	1210908.HSB1_37400	9.707e-08	64.0	COG0477@1|root,arCOG00134@2157|Archaea,2XTZA@28890|Euryarchaeota,23UTZ@183963|Halobacteria	183963|Halobacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2479407_2	266117.Rxyl_0200	1.075e-20	94.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4CSRQ@84995|Rubrobacteria	84995|Rubrobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
CMS3_k127_2479407_0	13035.Dacsa_1234	4.043e-70	252.0	COG0446@1|root,COG0446@2|Bacteria,1G2A3@1117|Cyanobacteria	1117|Cyanobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_2479407_1	706587.Desti_4174	5.325e-49	180.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2WJU0@28221|Deltaproteobacteria,2MQNQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS3_k127_25044_3	509190.Cseg_0737	0.0001746	48.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,2UHB3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_25044_2	526227.Mesil_0204	1.723e-48	178.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_25044_1	258533.BN977_03376	2.048e-71	254.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,2352X@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_25044_0	485913.Krac_6032	8.474e-125	425.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_2505247_0	1239962.C943_03647	8.37e-102	344.0	COG0438@1|root,COG0438@2|Bacteria,4NGFN@976|Bacteroidetes,47VW0@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2505247_1	857087.Metme_1190	2.951e-47	179.0	COG1216@1|root,COG1216@2|Bacteria,1RB30@1224|Proteobacteria,1RPV7@1236|Gammaproteobacteria,1XFX2@135618|Methylococcales	135618|Methylococcales	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2505247_4	383372.Rcas_0215	5.215e-05	55.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2G9QS@200795|Chloroflexi	200795|Chloroflexi	T	SMART RNA-processing protein HAT helix repeating-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_8
CMS3_k127_2505247_2	309801.trd_0452	1.136e-38	160.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi,27XSJ@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS3_k127_2518437_7	926550.CLDAP_01930	2.755e-28	124.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS3_k127_2518437_5	485913.Krac_2664	7.479e-50	190.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2518437_2	257310.BB1305	4.256e-85	287.0	COG1028@1|root,COG1028@2|Bacteria,1PP5H@1224|Proteobacteria,2VJ4Y@28216|Betaproteobacteria,3T2MY@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2518437_4	1254432.SCE1572_15570	3.018e-61	230.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
CMS3_k127_2518437_1	926569.ANT_13770	6.653e-212	671.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS3_k127_2518437_3	926569.ANT_13780	1.565e-72	255.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS3_k127_2518437_0	479434.Sthe_1421	1.064e-217	683.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi,27XYE@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_2518437_6	926569.ANT_13800	6.144e-38	147.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS3_k127_251960_2	926569.ANT_00490	1.971e-73	251.0	COG0433@1|root,COG0433@2|Bacteria,2G62A@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
CMS3_k127_251960_5	945713.IALB_0825	4.328e-18	91.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_251960_3	103690.17131306	1.937e-71	258.0	COG0477@1|root,COG2814@2|Bacteria,1G1MW@1117|Cyanobacteria,1HM0N@1161|Nostocales	1117|Cyanobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS3_k127_251960_1	324602.Caur_0546	3.336e-78	269.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_251960_6	324602.Caur_0547	6.527e-09	60.0	299CS@1|root,2ZWFP@2|Bacteria,2G9JC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_251960_4	324602.Caur_0548	3.04e-50	183.0	2E8I5@1|root,332W5@2|Bacteria,2G917@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_251960_0	28072.Nos7524_0707	5.707e-86	306.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnA	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
CMS3_k127_2520373_0	926569.ANT_14290	6.384e-18	98.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
CMS3_k127_2520373_1	357808.RoseRS_3879	3.482e-14	83.0	2ET4Z@1|root,33KP2@2|Bacteria,2G97T@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2525082_1	926569.ANT_30330	9.375e-60	221.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
CMS3_k127_2525082_0	926550.CLDAP_17120	4.519e-70	246.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi	200795|Chloroflexi	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
CMS3_k127_2525082_2	1123075.AUDP01000009_gene1177	3.676e-08	63.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,25CGI@186801|Clostridia,3WSCV@541000|Ruminococcaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
CMS3_k127_2532335_3	1045855.DSC_06110	1.144e-28	125.0	COG2197@1|root,COG2197@2|Bacteria,1RAQG@1224|Proteobacteria,1S31E@1236|Gammaproteobacteria,1X4HP@135614|Xanthomonadales	135614|Xanthomonadales	K	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2532335_4	1227739.Hsw_2088	3.456e-10	68.0	COG1633@1|root,COG1633@2|Bacteria,4NVQ2@976|Bacteroidetes,47XRQ@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
CMS3_k127_2532335_0	867845.KI911784_gene1010	5.045e-224	717.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_2532335_2	324602.Caur_1726	3.974e-57	204.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_2532335_1	316274.Haur_2008	1.529e-88	302.0	COG0300@1|root,COG0318@1|root,COG1020@1|root,COG3321@1|root,COG5322@1|root,COG0300@2|Bacteria,COG0318@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,COG5322@2|Bacteria,2G68I@200795|Chloroflexi,3765Y@32061|Chloroflexia	2|Bacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	ko:K13611,ko:K13612,ko:K15653	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Condensation,G3P_acyltransf,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Shikimate_DH,ketoacyl-synt
CMS3_k127_253703_3	479434.Sthe_1087	1.948e-36	146.0	COG1842@1|root,COG1842@2|Bacteria,2G8QB@200795|Chloroflexi,27Y1A@189775|Thermomicrobia	189775|Thermomicrobia	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS3_k127_253703_1	1123242.JH636436_gene557	6.372e-114	396.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_253703_2	479434.Sthe_3084	6.838e-63	229.0	COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,27YA5@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS3_k127_253703_0	1382356.JQMP01000001_gene745	2.044e-178	570.0	COG0402@1|root,COG0402@2|Bacteria,2G8TD@200795|Chloroflexi,27ZAA@189775|Thermomicrobia	189775|Thermomicrobia	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_253703_4	1132509.C447_09647	5.067e-33	144.0	COG1524@1|root,arCOG01378@2157|Archaea,2XVGR@28890|Euryarchaeota,23SZJ@183963|Halobacteria	183963|Halobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_253703_5	765420.OSCT_2328	2.364e-19	98.0	COG0457@1|root,COG0457@2|Bacteria,2G71Q@200795|Chloroflexi,376GZ@32061|Chloroflexia	32061|Chloroflexia	NU	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TPR_10,TPR_12,TPR_16,TPR_7
CMS3_k127_2563400_3	926550.CLDAP_15720	4.732e-81	278.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi	200795|Chloroflexi	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS3_k127_2563400_2	1163671.JAGI01000002_gene3787	1.482e-83	284.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,36EGR@31979|Clostridiaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2563400_5	1121090.KB894704_gene1575	4.088e-09	63.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,1ZG6N@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yqhY	-	-	-	-	-	-	-	-	-	-	-	Asp23
CMS3_k127_2563400_4	926569.ANT_14610	4.796e-39	150.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS3_k127_2563400_1	195250.CM001776_gene1332	3.527e-225	714.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1GYDR@1129|Synechococcus	1117|Cyanobacteria	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_2563400_0	926569.ANT_08730	5.109e-268	851.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
CMS3_k127_256585_0	1107311.Q767_08480	1.693e-49	203.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1076	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Autotransporter,DUF1929,Glyoxal_oxid_N,PA14
CMS3_k127_2573103_0	284031.JNXD01000008_gene2481	6.819e-54	202.0	COG0300@1|root,COG3695@1|root,COG0300@2|Bacteria,COG3695@2|Bacteria,2I3GA@201174|Actinobacteria	201174|Actinobacteria	L	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_2574019_0	1009370.ALO_06363	1.069e-143	475.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,4H3SW@909932|Negativicutes	909932|Negativicutes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS3_k127_2574019_1	485916.Dtox_1611	6.372e-86	295.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_2574019_2	555779.Dthio_PD3223	9.771e-41	159.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WIT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase, DHPS	-	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS3_k127_260530_0	1122176.KB903587_gene4433	1.076e-132	430.0	COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,1IP5X@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Alcohol dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,MaoC_dehydratas
CMS3_k127_260530_3	1347087.CBYO010000009_gene1396	0.0003464	51.0	COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli	91061|Bacilli	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
CMS3_k127_260530_1	324602.Caur_3059	6.715e-99	334.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi,376R4@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_260530_2	1173020.Cha6605_4325	1.292e-31	128.0	COG0730@1|root,COG0730@2|Bacteria,1G72I@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_2605707_4	867845.KI911784_gene426	2.706e-60	217.0	COG2378@1|root,COG2378@2|Bacteria,2G6Z2@200795|Chloroflexi,375E1@32061|Chloroflexia	32061|Chloroflexia	K	Helix-turn-helix type 11 domain protein	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
CMS3_k127_2605707_1	926550.CLDAP_09850	4.583e-86	301.0	COG0477@1|root,COG2814@2|Bacteria,2G5ZW@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2605707_2	266265.Bxe_C1280	1.854e-69	241.0	COG2312@1|root,COG2518@1|root,COG2312@2|Bacteria,COG2518@2|Bacteria,1MU2S@1224|Proteobacteria,2WFD9@28216|Betaproteobacteria,1KI0Q@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras,PCMT
CMS3_k127_2605707_0	316274.Haur_3367	1.517e-187	593.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
CMS3_k127_2605707_3	1499967.BAYZ01000052_gene4665	1.778e-66	247.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_2610183_1	926569.ANT_19230	1.133e-45	170.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS3_k127_2610183_0	326427.Cagg_1653	2.287e-51	188.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,375E7@32061|Chloroflexia	32061|Chloroflexia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS3_k127_2610183_2	439235.Dalk_3860	1.72e-15	89.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_2611118_2	1303692.SFUL_6283	2.116e-40	156.0	COG4221@1|root,COG4221@2|Bacteria,2I8VU@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_2611118_0	324602.Caur_0860	4.022e-72	259.0	COG0545@1|root,COG0545@2|Bacteria,2GA7H@200795|Chloroflexi,3762K@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidylprolyl isomerase FKBP-type	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
CMS3_k127_2611118_1	1487953.JMKF01000064_gene4735	1.006e-42	159.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1HAQ3@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS3_k127_2611292_0	483219.LILAB_26215	1.208e-144	492.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions,2X9RA@28221|Deltaproteobacteria,2YXVT@29|Myxococcales	28221|Deltaproteobacteria	IQ	Non-ribosomal peptide	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,PP-binding
CMS3_k127_261687_0	1128421.JAGA01000002_gene935	1.049e-169	544.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1,6.2.1.16	ko:K01895,ko:K01907	ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354,R01357	RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_261687_1	471853.Bcav_0979	3.002e-43	168.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS3_k127_261687_2	1449347.JQLN01000001_gene521	0.0008835	45.0	COG0745@1|root,COG0745@2|Bacteria,2HG0K@201174|Actinobacteria,2M5G6@2063|Kitasatospora	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2622690_3	525904.Tter_0083	8.133e-05	54.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NACHT,SIR2_2,TPR_1,TPR_11,TPR_2,TPR_8
CMS3_k127_2622690_2	357808.RoseRS_0270	3.531e-97	337.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_2622690_0	211165.AJLN01000116_gene3197	2.322e-246	767.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_2622690_1	329726.AM1_2452	1.095e-109	379.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_2624345_1	1121430.JMLG01000010_gene208	1.471e-81	280.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,26127@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_2624345_2	102129.Lepto7375DRAFT_7548	7.594e-60	219.0	28JAJ@1|root,2Z95C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2624345_0	1229780.BN381_640027	4.389e-119	395.0	COG1092@1|root,COG1092@2|Bacteria,2GXDD@201174|Actinobacteria	201174|Actinobacteria	J	Methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_2635812_3	1192034.CAP_3822	1.389e-12	75.0	COG4412@1|root,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36
CMS3_k127_2635812_2	1179773.BN6_60160	1.38e-28	134.0	COG1361@1|root,COG2373@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
CMS3_k127_2635812_0	1297742.A176_05808	5.471e-308	953.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WJY2@28221|Deltaproteobacteria,2Z30F@29|Myxococcales	28221|Deltaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_2635812_1	65393.PCC7424_1913	2.521e-51	192.0	COG1807@1|root,COG1807@2|Bacteria,1G424@1117|Cyanobacteria,3KHC9@43988|Cyanothece	1117|Cyanobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2636735_1	525904.Tter_0255	2.847e-73	261.0	COG0624@1|root,COG0624@2|Bacteria,2NNX2@2323|unclassified Bacteria	2|Bacteria	E	Peptidase dimerisation domain	ygeY	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_2636735_3	243365.CV_4109	1.69e-39	154.0	COG1434@1|root,COG1434@2|Bacteria,1RGR9@1224|Proteobacteria,2VRUA@28216|Betaproteobacteria,2KR46@206351|Neisseriales	206351|Neisseriales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS3_k127_2636735_4	240292.Ava_C0006	3.12e-38	154.0	COG0500@1|root,COG2226@2|Bacteria,1G31G@1117|Cyanobacteria,1HSVK@1161|Nostocales	1117|Cyanobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_2636735_2	311424.DhcVS_1254	5.877e-69	244.0	COG0134@1|root,COG0134@2|Bacteria,2G6GG@200795|Chloroflexi,34D20@301297|Dehalococcoidia	301297|Dehalococcoidia	E	indole-3-glycerol-phosphate synthase activity	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS3_k127_2636735_0	926569.ANT_05930	1.571e-123	405.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS3_k127_2636847_1	383372.Rcas_2512	3.876e-27	125.0	2EQIM@1|root,33I4N@2|Bacteria,2G9B7@200795|Chloroflexi,3773Z@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS3_k127_2636847_2	1128421.JAGA01000002_gene1062	4.657e-19	99.0	COG5180@1|root,COG5180@2|Bacteria,2NRZJ@2323|unclassified Bacteria	2|Bacteria	A	pathogenesis	CP_0034	-	-	ko:K02417,ko:K02519	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044,ko03012,ko03029	3.A.6.2,3.A.6.3	-	-	GPDPase_memb
CMS3_k127_2636847_0	42256.RradSPS_0735	5.556e-74	255.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2636847_3	1116232.AHBF01000150_gene2966	6.083e-08	61.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_2643234_1	1410668.JNKC01000001_gene1810	2.064e-72	254.0	COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,24JHQ@186801|Clostridia,36M0P@31979|Clostridiaceae	186801|Clostridia	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS3_k127_2643234_0	449447.MAE_11610	1.008e-121	410.0	28JCI@1|root,2Z976@2|Bacteria,1G4JJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2653407_0	926569.ANT_08710	8.731e-144	478.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS3_k127_2653407_1	926569.ANT_09200	1.268e-140	465.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_2653407_2	926569.ANT_08300	5.828e-89	297.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS3_k127_2653407_3	1379698.RBG1_1C00001G1052	4.482e-46	174.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
CMS3_k127_2660991_0	1121377.KB906404_gene2877	8.269e-111	396.0	COG0515@1|root,COG0515@2|Bacteria,1WIDK@1297|Deinococcus-Thermus	1121377.KB906404_gene2877|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2661423_1	1128421.JAGA01000002_gene272	1.129e-29	126.0	COG0340@1|root,COG0340@2|Bacteria,2NPG2@2323|unclassified Bacteria	2|Bacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_2661423_0	1128421.JAGA01000004_gene2674	1.898e-223	704.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
CMS3_k127_2668104_7	517418.Ctha_0128	9.902e-97	325.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,DUF116
CMS3_k127_2668104_4	517418.Ctha_0127	7.295e-114	376.0	COG1856@1|root,COG1856@2|Bacteria	2|Bacteria	S	radical SAM domain protein	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
CMS3_k127_2668104_2	517418.Ctha_0126	2.574e-128	427.0	COG2516@1|root,COG2516@2|Bacteria	2|Bacteria	K	radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_2668104_9	517418.Ctha_0125	3.658e-73	259.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
CMS3_k127_2668104_21	3847.GLYMA01G38930.1	5.869e-05	48.0	COG0526@1|root,KOG0907@2759|Eukaryota,37QX7@33090|Viridiplantae,3G7JX@35493|Streptophyta,4JKD1@91835|fabids	35493|Streptophyta	O	Thioredoxin-like protein HCF164	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009636,GO:0009987,GO:0010190,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0017004,GO:0019725,GO:0022607,GO:0031976,GO:0031977,GO:0031984,GO:0033554,GO:0034357,GO:0034599,GO:0034622,GO:0042221,GO:0042592,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055035,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070887,GO:0071840,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CMS3_k127_2668104_12	635013.TherJR_0769	1.062e-50	186.0	COG0243@1|root,COG0243@2|Bacteria,1V2XY@1239|Firmicutes,24GWZ@186801|Clostridia,262P2@186807|Peptococcaceae	186801|Clostridia	C	PFAM molybdopterin oxidoreductase Fe4S4 region	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
CMS3_k127_2668104_0	439292.Bsel_1218	1.35e-286	902.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1TQIX@1239|Firmicutes,4HUSZ@91061|Bacilli	91061|Bacilli	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
CMS3_k127_2668104_8	479434.Sthe_3389	2.383e-79	273.0	COG0437@1|root,COG0437@2|Bacteria,2G9ZX@200795|Chloroflexi,27Y09@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S binding domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3
CMS3_k127_2668104_13	1128421.JAGA01000002_gene1704	1.827e-43	170.0	COG3301@1|root,COG3301@2|Bacteria,2NQX4@2323|unclassified Bacteria	2|Bacteria	P	Polysulfide reductase	nrfD	-	-	-	-	-	-	-	-	-	-	-	NrfD
CMS3_k127_2668104_14	1128421.JAGA01000002_gene1531	4.188e-34	143.0	COG3058@1|root,COG3058@2|Bacteria,2NRGD@2323|unclassified Bacteria	2|Bacteria	O	Protein involved in formate dehydrogenase formation	fdhE	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
CMS3_k127_2668104_18	316274.Haur_2917	4.487e-20	103.0	COG4805@1|root,COG4805@2|Bacteria,2G8D3@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2668104_6	1382356.JQMP01000003_gene1909	1.828e-103	347.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,27XJW@189775|Thermomicrobia	189775|Thermomicrobia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS3_k127_2668104_16	1341151.ASZU01000014_gene2209	5.519e-26	115.0	28P6Z@1|root,2ZC1H@2|Bacteria,1V318@1239|Firmicutes,4HFZ4@91061|Bacilli	91061|Bacilli	S	Protein of unknown function with HXXEE motif	-	-	-	-	-	-	-	-	-	-	-	-	HXXEE
CMS3_k127_2668104_11	552811.Dehly_0442	2.037e-58	216.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
CMS3_k127_2668104_20	1116472.MGMO_108c00010	1.936e-07	63.0	COG2010@1|root,COG4885@1|root,COG2010@2|Bacteria,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,1RWBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3
CMS3_k127_2668104_19	926569.ANT_19420	1.2e-19	102.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
CMS3_k127_2668104_15	926569.ANT_24750	1.193e-28	123.0	COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_2668104_17	926569.ANT_24760	2.773e-23	108.0	2DSXF@1|root,33HTI@2|Bacteria,2G9HW@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS3_k127_2668104_1	926569.ANT_24770	1.107e-148	485.0	COG5557@1|root,COG5557@2|Bacteria,2G68D@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS3_k127_2668104_5	269799.Gmet_1811	9.272e-104	342.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_2668104_3	926569.ANT_24790	6.732e-118	397.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi	200795|Chloroflexi	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
CMS3_k127_2668706_2	926550.CLDAP_29930	1.709e-73	259.0	COG0438@1|root,COG0438@2|Bacteria,2G82Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_2668706_0	926550.CLDAP_29920	1.259e-83	292.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_2668706_4	441769.ABFU01000017_gene3523	5.411e-49	182.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,1ZAT4@1386|Bacillus	91061|Bacilli	KT	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_2668706_1	357808.RoseRS_2402	9.956e-78	283.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
CMS3_k127_2668706_6	316274.Haur_1609	3.534e-15	80.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K03407,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_2668706_3	760192.Halhy_2996	1.994e-52	190.0	COG3832@1|root,COG3832@2|Bacteria,4P9AM@976|Bacteroidetes,1IZRB@117747|Sphingobacteriia	976|Bacteroidetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2668706_5	1095769.CAHF01000014_gene3157	1.296e-21	98.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,475VS@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD3	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS3_k127_2668764_1	316274.Haur_0839	7.188e-90	304.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi,37631@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_2668764_0	1070774.J07HN4v3_00095	3.624e-91	313.0	arCOG07655@1|root,arCOG07655@2157|Archaea,2Y71F@28890|Euryarchaeota,23UID@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2670130_4	926569.ANT_16350	2.748e-66	236.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS3_k127_2670130_9	1380393.JHVP01000020_gene233	7.288e-08	61.0	COG1846@1|root,COG1846@2|Bacteria,2GMV1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_2670130_1	345341.KUTG_03378	6.47e-104	383.0	COG0841@1|root,COG0841@2|Bacteria,2GMQX@201174|Actinobacteria,4E08W@85010|Pseudonocardiales	201174|Actinobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_2670130_0	1128421.JAGA01000002_gene569	3.349e-157	514.0	COG1178@1|root,COG1178@2|Bacteria	2|Bacteria	P	thiamine transport	thiP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	iAPECO1_1312.APECO1_1915,iECIAI1_1343.ECIAI1_0067,iECO103_1326.ECO103_0068,iECO111_1330.ECO111_0069,iECO26_1355.ECO26_0069,iECOK1_1307.ECOK1_0068,iECS88_1305.ECS88_0072,iECSE_1348.ECSE_0067,iECUMN_1333.ECUMN_0068,iPC815.YPO0521,iSF_1195.SF0062,iSFxv_1172.SFxv_0064,iS_1188.S0064,iUMN146_1321.UM146_23130,iUTI89_1310.UTI89_C0075	BPD_transp_1
CMS3_k127_2670130_2	1128421.JAGA01000002_gene217	7.685e-86	297.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	fbpC	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K02052,ko:K02062,ko:K11072	ko02010,ko02024,map02010,map02024	M00190,M00191,M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11,3.A.1.11.1,3.A.1.19	-	-	ABC_tran,TOBE_2
CMS3_k127_2670130_3	926569.ANT_19920	2.147e-66	239.0	COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi	200795|Chloroflexi	M	SMART PDZ DHR GLGF domain protein	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CMS3_k127_2670130_5	357808.RoseRS_3973	2.318e-42	169.0	COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi,375QB@32061|Chloroflexia	32061|Chloroflexia	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_2670130_6	1317124.DW2_12435	1.198e-27	118.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2U5S9@28211|Alphaproteobacteria,2XNZN@285107|Thioclava	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_2670130_7	589865.DaAHT2_0432	1.301e-20	96.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MMAN@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_2670130_8	272134.KB731326_gene351	6.264e-18	91.0	COG0451@1|root,COG0451@2|Bacteria,1G3KY@1117|Cyanobacteria,1HBRG@1150|Oscillatoriales	1117|Cyanobacteria	GM	NAD dependent epimerase dehydratase family	-	-	1.1.1.339	ko:K19180	ko00523,ko01130,map00523,map01130	-	R10190	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS3_k127_2671599_1	1283287.KB822575_gene188	5.884e-37	154.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DNDD@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_2671599_0	2045.KR76_01040	5.703e-131	441.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4DNJ7@85009|Propionibacteriales	201174|Actinobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CMS3_k127_2682231_0	926569.ANT_03160	1.53e-178	576.0	COG1164@1|root,COG1164@2|Bacteria,2G5SV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS3_k127_2682231_1	1173022.Cri9333_0749	1.181e-147	474.0	COG0667@1|root,COG0667@2|Bacteria,1G3WV@1117|Cyanobacteria,1HH84@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS3_k127_2700699_2	715451.ambt_19770	0.0002684	55.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,DUF642,HemolysinCabind,Peptidase_M10,Peptidase_M10_C
CMS3_k127_2700699_0	497964.CfE428DRAFT_2480	1.447e-16	87.0	2AEIE@1|root,314DU@2|Bacteria,46WQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2700699_1	1379698.RBG1_1C00001G1207	3.53e-12	80.0	COG1807@1|root,COG3063@1|root,COG1807@2|Bacteria,COG3063@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_16,TPR_8
CMS3_k127_2725142_1	926550.CLDAP_06940	7.719e-44	162.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS3_k127_2725142_0	926550.CLDAP_06930	8.916e-65	239.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS3_k127_2725142_2	67352.JODS01000028_gene2326	1.969e-10	69.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria	201174|Actinobacteria	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_2730292_1	1384056.N787_07495	6.983e-10	72.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S0D5@1236|Gammaproteobacteria,1X4Y2@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_2730292_0	926569.ANT_29650	1.835e-25	111.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_2741593_1	1192034.CAP_8990	9.172e-10	68.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,434QI@68525|delta/epsilon subdivisions,2X8Z6@28221|Deltaproteobacteria,2Z152@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2741593_0	313612.L8106_03012	1.766e-46	186.0	COG5635@1|root,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
CMS3_k127_2766175_1	926550.CLDAP_24510	3.725e-212	687.0	COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi	200795|Chloroflexi	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CMS3_k127_2766175_3	316274.Haur_2467	7.313e-90	319.0	COG1609@1|root,COG1609@2|Bacteria,2G8RS@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_2766175_0	926550.CLDAP_24510	0.0	1109.0	COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi	200795|Chloroflexi	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CMS3_k127_2766175_6	243233.MCA2199	4.929e-14	82.0	COG0666@1|root,COG0666@2|Bacteria,1PEPV@1224|Proteobacteria,1SFWB@1236|Gammaproteobacteria,1XFT1@135618|Methylococcales	135618|Methylococcales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
CMS3_k127_2766175_7	1380393.JHVP01000006_gene3909	1.575e-07	62.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4ET14@85013|Frankiales	201174|Actinobacteria	L	helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS3_k127_2766175_5	632335.Calkr_2079	3.716e-16	89.0	COG4974@1|root,COG4974@2|Bacteria,1UYED@1239|Firmicutes,25C48@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
CMS3_k127_2766175_2	926550.CLDAP_29120	5.083e-181	574.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_2766175_4	316274.Haur_1889	4.517e-48	188.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_2769569_5	765420.OSCT_0023	5.172e-32	135.0	COG3023@1|root,COG3209@1|root,COG3023@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2,PG_binding_1
CMS3_k127_2769569_3	1122919.KB905555_gene984	1.096e-42	169.0	COG2890@1|root,COG2890@2|Bacteria,1V4FF@1239|Firmicutes,4HHHN@91061|Bacilli,26XJ6@186822|Paenibacillaceae	91061|Bacilli	J	RRNA methyltransferase AviRa	-	-	2.1.1.209	ko:K21515	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	AviRa
CMS3_k127_2769569_4	1370125.AUWT01000094_gene5196	5.066e-36	143.0	COG3945@1|root,COG3945@2|Bacteria,2I46K@201174|Actinobacteria,23BMN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_2769569_0	65093.PCC7418_1017	1.089e-138	451.0	COG2942@1|root,COG2942@2|Bacteria,1G04P@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
CMS3_k127_2769569_2	319225.Plut_1793	1.47e-44	173.0	COG4123@1|root,COG4123@2|Bacteria	2|Bacteria	AJ	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_2769569_1	1304876.AZVC01000009_gene3468	3.977e-112	367.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
CMS3_k127_2772885_1	118166.JH976537_gene4842	1.657e-67	234.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HAGW@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS3_k127_2772885_0	266117.Rxyl_2357	4.982e-85	290.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_2772889_4	1089545.KB913037_gene1349	5.287e-09	69.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,SEFIR,TPR_10,TPR_12,TPR_7,Trans_reg_C
CMS3_k127_2772889_0	765420.OSCT_0768	1.793e-85	308.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CMS3_k127_2772889_3	324602.Caur_0300	3.763e-11	69.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2772889_2	926569.ANT_00640	4.758e-61	217.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS3_k127_2772889_1	309807.SRU_0113	2.132e-62	218.0	COG0146@1|root,COG0146@2|Bacteria,4PM5E@976|Bacteroidetes,1FJR8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS3_k127_2781901_0	1382306.JNIM01000001_gene3438	1.968e-81	283.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_2781901_1	1210884.HG799462_gene9019	7.841e-27	119.0	2FDUG@1|root,345V3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2782268_0	926569.ANT_27410	0.0	1132.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS3_k127_2782268_1	926569.ANT_15180	2.165e-27	114.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS3_k127_2782268_2	1121481.AUAS01000003_gene3661	1.203e-16	93.0	COG4932@1|root,COG5184@1|root,COG5492@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NUJ5@976|Bacteroidetes,47XC0@768503|Cytophagia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2785121_7	665952.HMPREF1015_01866	3.668e-08	66.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1ZAT8@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2785121_6	867845.KI911784_gene3614	5.617e-19	100.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,AAA_22,AAA_35
CMS3_k127_2785121_2	926550.CLDAP_10520	1.143e-108	381.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_2785121_1	926550.CLDAP_04870	7.987e-126	425.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_2785121_5	326427.Cagg_0408	2.187e-22	112.0	COG2723@1|root,COG2723@2|Bacteria,2GBIH@200795|Chloroflexi,3771Z@32061|Chloroflexia	32061|Chloroflexia	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FlaA,Glyco_hydro_42,Glyco_hydro_cc
CMS3_k127_2785121_3	1242864.D187_003310	1.096e-86	299.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_2785121_0	290397.Adeh_2070	1.368e-132	432.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_2785121_4	264732.Moth_2251	6.123e-26	108.0	COG0119@1|root,COG0119@2|Bacteria,1TRIK@1239|Firmicutes,249Q4@186801|Clostridia,42EVB@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_2794832_0	383372.Rcas_1300	1.318e-283	921.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
CMS3_k127_2800220_1	215803.DB30_2975	4.719e-17	97.0	2F32K@1|root,2ZBI3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2800220_0	449447.MAE_11600	4.535e-205	687.0	2DB7G@1|root,2Z7M5@2|Bacteria,1G3PP@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2800220_2	1192034.CAP_5261	1.937e-08	59.0	28JCI@1|root,2Z976@2|Bacteria,1RDT1@1224|Proteobacteria,438HS@68525|delta/epsilon subdivisions,2X3SM@28221|Deltaproteobacteria,2YX0D@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_280191_8	1280954.HPO_10542	8.733e-12	70.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,43WKC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
CMS3_k127_280191_2	221288.JH992901_gene2871	1.952e-95	327.0	COG0654@1|root,COG0654@2|Bacteria,1G27V@1117|Cyanobacteria,1JGY3@1189|Stigonemataceae	1117|Cyanobacteria	CH	Monooxygenase fad-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_280191_0	1521187.JPIM01000103_gene1042	2.952e-236	754.0	COG1529@1|root,COG1529@2|Bacteria,2G82V@200795|Chloroflexi,3764T@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_280191_6	7213.XP_004519941.1	8.287e-32	139.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa,3CSKJ@33213|Bilateria,41YHD@6656|Arthropoda,3SIXR@50557|Insecta,4519D@7147|Diptera	33208|Metazoa	M	Pectinacetylesterase	NOTUM	GO:0000902,GO:0000904,GO:0003002,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008045,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009952,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0012505,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019538,GO:0019637,GO:0021532,GO:0021915,GO:0022008,GO:0023051,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030163,GO:0030178,GO:0030182,GO:0031175,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0035220,GO:0035222,GO:0035295,GO:0035601,GO:0036211,GO:0040011,GO:0042157,GO:0042159,GO:0042221,GO:0042330,GO:0042578,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046486,GO:0046488,GO:0048070,GO:0048073,GO:0048076,GO:0048190,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0052689,GO:0060429,GO:0060828,GO:0061564,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0090090,GO:0097485,GO:0098732,GO:0120036,GO:0120039,GO:1901135,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1990697,GO:1990699	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_280191_3	1123239.KB898632_gene2197	1.279e-93	316.0	COG0842@1|root,COG0842@2|Bacteria,1TS7U@1239|Firmicutes,4HCH1@91061|Bacilli	91061|Bacilli	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_280191_1	1395513.P343_12985	5.688e-116	383.0	COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,4HB5U@91061|Bacilli,26PE5@186821|Sporolactobacillaceae	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_280191_5	1408433.JHXV01000011_gene2081	5.4e-59	212.0	arCOG07533@1|root,31XFQ@2|Bacteria,4P9XQ@976|Bacteroidetes,1ICVA@117743|Flavobacteriia,2PBXP@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
CMS3_k127_280191_7	329726.AM1_6084	7.819e-23	102.0	2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_280191_4	574375.BAGA_10105	1.471e-84	291.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_2802701_7	1128421.JAGA01000003_gene3534	1.873e-43	165.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS3_k127_2802701_6	926569.ANT_04570	6.197e-46	171.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
CMS3_k127_2802701_2	383372.Rcas_4254	8.387e-82	278.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
CMS3_k127_2802701_8	926569.ANT_12920	2.77e-39	161.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
CMS3_k127_2802701_3	357808.RoseRS_3344	2.479e-69	244.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS3_k127_2802701_5	1172188.KB911821_gene2078	2.234e-53	203.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
CMS3_k127_2802701_0	926569.ANT_17250	2.025e-118	389.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_2802701_11	1038862.KB893884_gene601	4.576e-16	87.0	COG4126@1|root,COG4126@2|Bacteria,1R3SB@1224|Proteobacteria,2U0YJ@28211|Alphaproteobacteria,3JWHD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	AroM protein	-	-	-	ko:K14591	-	-	-	-	ko00000	-	-	-	AroM
CMS3_k127_2802701_1	573413.Spirs_0115	1.948e-108	367.0	COG0044@1|root,COG0044@2|Bacteria,2J6KK@203691|Spirochaetes	203691|Spirochaetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
CMS3_k127_2802701_4	795797.C497_01345	5.118e-56	213.0	COG0076@1|root,arCOG00027@2157|Archaea,2XV76@28890|Euryarchaeota,23UJY@183963|Halobacteria	183963|Halobacteria	E	COG0076 Glutamate decarboxylase and related PLP-dependent proteins	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
CMS3_k127_2802701_12	32057.KB217478_gene4419	5.041e-16	88.0	28N7T@1|root,2ZBCE@2|Bacteria,1G50K@1117|Cyanobacteria,1HNYU@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2802701_10	1304872.JAGC01000009_gene530	8.089e-27	119.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,42X7G@68525|delta/epsilon subdivisions,2WSX9@28221|Deltaproteobacteria,2MDSS@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NnrU,PEMT
CMS3_k127_2802701_9	391038.Bphy_7286	4.314e-31	128.0	2A7SR@1|root,30WRT@2|Bacteria,1N1R6@1224|Proteobacteria,2W72Y@28216|Betaproteobacteria,1KDNC@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2802701_13	452637.Oter_0843	3.413e-10	61.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,46UHB@74201|Verrucomicrobia,3K7CZ@414999|Opitutae	2|Bacteria	C	PFAM FAD linked oxidase domain protein	MA20_43170	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
CMS3_k127_2803906_2	1123228.AUIH01000045_gene1874	0.000959	47.0	COG2717@1|root,COG2717@2|Bacteria,1PUNJ@1224|Proteobacteria,1SUFV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferric reductase like transmembrane component	-	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
CMS3_k127_2803906_0	306281.AJLK01000081_gene1682	2.065e-285	911.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_2803906_1	32049.SYNPCC7002_A1173	5.158e-54	199.0	COG0318@1|root,COG0596@1|root,COG3321@1|root,COG0318@2|Bacteria,COG0596@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1H02I@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG3321 Polyketide synthase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Abhydrolase_1,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Sulfotransfer_3,ketoacyl-synt
CMS3_k127_2807334_1	1410653.JHVC01000031_gene852	1.016e-47	190.0	COG3391@1|root,COG3391@2|Bacteria,1V6KE@1239|Firmicutes	1239|Firmicutes	DZ	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_2807334_2	331869.BAL199_13383	2.344e-26	115.0	COG1514@1|root,COG1514@2|Bacteria,1NPV2@1224|Proteobacteria,2UI49@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CMS3_k127_2807334_3	1038859.AXAU01000013_gene6598	6.372e-23	102.0	COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS3_k127_2807334_0	1128421.JAGA01000003_gene3538	1.861e-52	196.0	COG2353@1|root,COG2353@2|Bacteria,2NR1J@2323|unclassified Bacteria	2|Bacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_2811507_0	926569.ANT_05900	1.357e-180	573.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2811507_1	1254432.SCE1572_36870	4.666e-40	158.0	COG4377@1|root,COG4377@2|Bacteria,1QACG@1224|Proteobacteria,43DZN@68525|delta/epsilon subdivisions,2WZAB@28221|Deltaproteobacteria,2Z1PM@29|Myxococcales	28221|Deltaproteobacteria	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
CMS3_k127_2815268_1	344747.PM8797T_28334	2.251e-06	55.0	2FE2U@1|root,3462X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2815268_0	156889.Mmc1_1355	9.481e-240	777.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,2TUMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG0553 Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
CMS3_k127_2816327_4	926569.ANT_05390	2.196e-59	209.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS3_k127_2816327_7	316274.Haur_3525	1.229e-08	66.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	2.7.1.89	ko:K07251,ko:K18844	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000,ko01504	-	-	-	APH,Choline_kinase
CMS3_k127_2816327_0	324602.Caur_3031	9.87e-128	418.0	COG1131@1|root,COG1131@2|Bacteria,2G6HN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2816327_2	324602.Caur_3032	3.458e-91	316.0	COG1668@1|root,COG1668@2|Bacteria,2G7R2@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_2816327_1	326427.Cagg_0520	4.224e-99	335.0	COG0842@1|root,COG0842@2|Bacteria,2G7IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_2816327_3	926550.CLDAP_32000	1.019e-79	271.0	COG0225@1|root,COG0225@2|Bacteria,2G6JK@200795|Chloroflexi	200795|Chloroflexi	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS3_k127_2816327_6	134676.ACPL_7732	2.266e-24	115.0	COG0454@1|root,COG0456@2|Bacteria,2I9GA@201174|Actinobacteria,4DD5V@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2816327_5	1121405.dsmv_2022	1.156e-49	183.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WKU4@28221|Deltaproteobacteria,2MIVX@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS3_k127_2816598_2	709986.Deima_2859	3.582e-19	96.0	COG0220@1|root,COG0220@2|Bacteria,1WI0J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS3_k127_2816598_0	1005048.CFU_3993	3.068e-151	508.0	COG0318@1|root,COG2267@1|root,COG0318@2|Bacteria,COG2267@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,473Q4@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_2816598_1	525904.Tter_2711	2.404e-39	154.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung	-	3.2.2.27	ko:K03648,ko:K21929	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
CMS3_k127_2820096_1	316274.Haur_0023	1.042e-97	332.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_282064_4	1190606.AJYG01000029_gene2978	1.32e-37	148.0	COG3714@1|root,COG3714@2|Bacteria,1PN0I@1224|Proteobacteria,1RNUV@1236|Gammaproteobacteria,1Y26V@135623|Vibrionales	135623|Vibrionales	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
CMS3_k127_282064_2	1218075.BAYA01000001_gene159	3.103e-68	243.0	COG0500@1|root,COG0500@2|Bacteria,1QWHM@1224|Proteobacteria,2WH0P@28216|Betaproteobacteria,1KIGF@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_282064_3	1200792.AKYF01000018_gene5774	2.293e-58	213.0	2DM3D@1|root,31J5I@2|Bacteria,1UHTM@1239|Firmicutes,4IS9A@91061|Bacilli,27750@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2785)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2785
CMS3_k127_282064_1	1087448.Eab7_0977	2.306e-76	267.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HB1P@91061|Bacilli,3WG1Z@539002|Bacillales incertae sedis	91061|Bacilli	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
CMS3_k127_282064_5	202752.JL53_00735	1.802e-26	115.0	COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,26KR3@186820|Listeriaceae	91061|Bacilli	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS3_k127_282064_0	485913.Krac_11786	3.256e-112	377.0	COG0249@1|root,COG0249@2|Bacteria,2G8CJ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA mismatch repair protein MutS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
CMS3_k127_2823818_0	926569.ANT_23360	2.25e-84	290.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_2823818_1	926569.ANT_23350	1.246e-65	230.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS3_k127_2838308_0	926569.ANT_11920	1.58e-37	156.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
CMS3_k127_2838308_1	926569.ANT_31290	2.186e-27	128.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
CMS3_k127_2839682_1	7918.ENSLOCP00000003540	1.367e-07	64.0	KOG3599@1|root,KOG3599@2759|Eukaryota,38DQ4@33154|Opisthokonta,3BCZ5@33208|Metazoa,3CYFS@33213|Bilateria,485XP@7711|Chordata,48YBW@7742|Vertebrata,49R8K@7898|Actinopterygii	33208|Metazoa	PT	Polycystic kidney disease 1 (autosomal dominant)	PKD1	GO:0000003,GO:0000079,GO:0000139,GO:0001501,GO:0001502,GO:0001568,GO:0001655,GO:0001656,GO:0001701,GO:0001763,GO:0001822,GO:0001823,GO:0001889,GO:0001890,GO:0001892,GO:0001932,GO:0001934,GO:0001944,GO:0001945,GO:0002009,GO:0002133,GO:0003006,GO:0003338,GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005798,GO:0005886,GO:0005887,GO:0005929,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006611,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006913,GO:0006950,GO:0007049,GO:0007050,GO:0007154,GO:0007155,GO:0007156,GO:0007160,GO:0007161,GO:0007163,GO:0007165,GO:0007204,GO:0007259,GO:0007275,GO:0007346,GO:0007399,GO:0007417,GO:0007507,GO:0007548,GO:0008104,GO:0008150,GO:0008152,GO:0008324,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009986,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010564,GO:0010604,GO:0010628,GO:0012505,GO:0015031,GO:0015075,GO:0015085,GO:0015267,GO:0015318,GO:0015833,GO:0016020,GO:0016021,GO:0016310,GO:0016323,GO:0016328,GO:0018105,GO:0018193,GO:0018209,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0021510,GO:0021915,GO:0022402,GO:0022414,GO:0022610,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0023052,GO:0030001,GO:0030003,GO:0030010,GO:0030155,GO:0030162,GO:0030323,GO:0030324,GO:0030660,GO:0031090,GO:0031224,GO:0031226,GO:0031253,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031399,GO:0031401,GO:0031410,GO:0031514,GO:0031589,GO:0031657,GO:0031659,GO:0031982,GO:0031984,GO:0032092,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0033674,GO:0034220,GO:0034405,GO:0034613,GO:0035239,GO:0035295,GO:0035556,GO:0036211,GO:0036303,GO:0042176,GO:0042325,GO:0042327,GO:0042592,GO:0042886,GO:0042994,GO:0042995,GO:0043009,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0043393,GO:0043412,GO:0043433,GO:0043549,GO:0043588,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044325,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045184,GO:0045185,GO:0045737,GO:0045786,GO:0045787,GO:0045859,GO:0045860,GO:0045893,GO:0045935,GO:0045937,GO:0045944,GO:0046873,GO:0046907,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048565,GO:0048568,GO:0048608,GO:0048705,GO:0048729,GO:0048731,GO:0048732,GO:0048754,GO:0048806,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0050982,GO:0051090,GO:0051098,GO:0051099,GO:0051128,GO:0051168,GO:0051169,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051220,GO:0051234,GO:0051235,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051338,GO:0051347,GO:0051480,GO:0051493,GO:0051606,GO:0051641,GO:0051649,GO:0051716,GO:0051726,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0055123,GO:0060170,GO:0060236,GO:0060255,GO:0060428,GO:0060429,GO:0060541,GO:0060562,GO:0060674,GO:0060993,GO:0061008,GO:0061136,GO:0061138,GO:0061326,GO:0061333,GO:0061448,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070062,GO:0070507,GO:0070588,GO:0070727,GO:0070838,GO:0071702,GO:0071704,GO:0071705,GO:0071900,GO:0071902,GO:0071944,GO:0072001,GO:0072006,GO:0072009,GO:0072014,GO:0072017,GO:0072021,GO:0072028,GO:0072044,GO:0072070,GO:0072073,GO:0072078,GO:0072080,GO:0072088,GO:0072156,GO:0072163,GO:0072164,GO:0072170,GO:0072173,GO:0072176,GO:0072177,GO:0072205,GO:0072207,GO:0072210,GO:0072218,GO:0072234,GO:0072235,GO:0072236,GO:0072237,GO:0072243,GO:0072273,GO:0072282,GO:0072287,GO:0072358,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0080090,GO:0090224,GO:0097696,GO:0097708,GO:0098588,GO:0098590,GO:0098609,GO:0098655,GO:0098660,GO:0098662,GO:0098742,GO:0098743,GO:0098771,GO:0098791,GO:0098805,GO:0120025,GO:0120038,GO:1901564,GO:1901987,GO:1901990,GO:1902680,GO:1902806,GO:1903050,GO:1903362,GO:1903506,GO:1903508,GO:1903561,GO:1904029,GO:1904031,GO:2000045,GO:2000112,GO:2001141	-	ko:K04985	-	-	-	-	ko00000,ko04040,ko04091,ko04812	1.A.5.1.1	-	-	LRR_8,Lectin_C,PKD,PKD_channel,PLAT,REJ,WSC
CMS3_k127_2839682_0	1192034.CAP_4066	1.12e-40	171.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
CMS3_k127_2844495_1	368408.Tpen_0797	7.002e-18	89.0	COG1786@1|root,arCOG04279@2157|Archaea,2XR59@28889|Crenarchaeota	28889|Crenarchaeota	C	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
CMS3_k127_2844495_0	383372.Rcas_2809	3.229e-77	275.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2848471_1	649638.Trad_2654	5.954e-123	402.0	COG1087@1|root,COG1087@2|Bacteria	2|Bacteria	M	UDP-glucose 4-epimerase activity	galE	-	5.1.3.2,5.1.3.25,5.1.3.6	ko:K01784,ko:K08679,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R01385,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_2848471_0	926550.CLDAP_35790	2.575e-144	479.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_2848471_2	1291050.JAGE01000001_gene1683	6.267e-06	57.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHVR@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
CMS3_k127_284921_6	270374.MELB17_00250	2.736e-15	90.0	COG0326@1|root,COG3170@1|root,COG0326@2|Bacteria,COG3170@2|Bacteria,1QWE9@1224|Proteobacteria,1S665@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Molecular chaperone. Has ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883
CMS3_k127_284921_3	485913.Krac_5203	1.996e-55	202.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS3_k127_284921_5	485913.Krac_7418	1.358e-44	164.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS3_k127_284921_4	357808.RoseRS_3423	1.979e-45	178.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Met_10,Methyltransf_21,rRNA_methylase
CMS3_k127_284921_2	37919.EP51_03085	8.585e-79	266.0	2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria,4G1XB@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_284921_1	448385.sce2265	6.965e-95	323.0	29GQM@1|root,2ZS2M@2|Bacteria,1Q1RE@1224|Proteobacteria,437EU@68525|delta/epsilon subdivisions,2X2M3@28221|Deltaproteobacteria,2Z053@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4419)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4419
CMS3_k127_284921_7	1484460.JSWG01000001_gene2444	1.498e-05	54.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6,4.1.3.1	ko:K01637,ko:K01652	ko00290,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00290,map00630,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00012,M00019,M00570	R00006,R00014,R00226,R00479,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00311,RC00313,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PAP2,TPP_enzyme_N
CMS3_k127_2853407_1	1123277.KB893197_gene6111	7.068e-52	198.0	COG3203@1|root,COG4386@1|root,COG3203@2|Bacteria,COG4386@2|Bacteria,4PM6S@976|Bacteroidetes,47Y33@768503|Cytophagia	976|Bacteroidetes	M	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_2853407_0	1521187.JPIM01000102_gene3723	4.424e-88	308.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS3_k127_2853407_2	1206737.BAGF01000150_gene6092	5.164e-51	205.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,2I2RH@201174|Actinobacteria,4G8NE@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
CMS3_k127_2862100_0	326427.Cagg_2765	5.077e-69	248.0	COG0520@1|root,COG0520@2|Bacteria,2G7N0@200795|Chloroflexi,377HP@32061|Chloroflexia	32061|Chloroflexia	H	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_2862100_1	749222.Nitsa_0316	3.681e-18	98.0	28J2S@1|root,2Z8Z4@2|Bacteria,1NQU2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2870971_0	326427.Cagg_3193	4.41e-240	771.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi,374YG@32061|Chloroflexia	32061|Chloroflexia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_2870971_1	926569.ANT_12630	3.223e-111	367.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS3_k127_2871854_0	696281.Desru_1400	7.063e-54	204.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.5.1.106	ko:K15357	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_3,Abhydrolase_6,Hydrolase_4
CMS3_k127_2871854_1	926569.ANT_25600	2.003e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
CMS3_k127_2875122_2	1297581.H919_10223	1.672e-99	330.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,21WNF@150247|Anoxybacillus	91061|Bacilli	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS3_k127_2875122_1	926550.CLDAP_21290	2.435e-110	370.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi	200795|Chloroflexi	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS3_k127_2875122_0	926550.CLDAP_24680	7.996e-167	532.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_2875122_4	391625.PPSIR1_17460	5.131e-06	57.0	2BR3U@1|root,32K1T@2|Bacteria,1Q2KE@1224|Proteobacteria,433U9@68525|delta/epsilon subdivisions,2X3H0@28221|Deltaproteobacteria,2YW23@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2875122_3	357808.RoseRS_3845	3.014e-61	234.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2875604_0	1385935.N836_20445	0.0	1193.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
CMS3_k127_2879566_2	926550.CLDAP_40260	3.063e-20	104.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K13009,ko:K18814	-	-	-	-	ko00000,ko01000,ko01005,ko02000	9.B.67.1	-	-	Wzy_C
CMS3_k127_2879566_0	926569.ANT_17090	7.816e-88	309.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2G5WM@200795|Chloroflexi	200795|Chloroflexi	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,GNVR,Wzz
CMS3_k127_2879566_1	1353531.AZNX01000012_gene3945	2.832e-29	120.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,2TT7Q@28211|Alphaproteobacteria,4BAEY@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	GDP-mannose 4,6 dehydratase	-	-	4.1.1.35,5.1.3.10,5.1.3.2,5.1.3.25	ko:K01784,ko:K08678,ko:K12454,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R01384,R02984,R04266,R10279	RC00289,RC00508,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_2882024_8	886293.Sinac_1733	3.968e-15	79.0	2EFHE@1|root,3399Z@2|Bacteria,2J10E@203682|Planctomycetes	203682|Planctomycetes	S	WXG100 protein secretion system (Wss), protein YukD	-	-	-	-	-	-	-	-	-	-	-	-	YukD
CMS3_k127_2882024_5	1173028.ANKO01000111_gene4982	1.052e-36	145.0	COG5078@1|root,COG5078@2|Bacteria,1GDKY@1117|Cyanobacteria,1HFCY@1150|Oscillatoriales	1117|Cyanobacteria	O	Ubiquitin-conjugating enzyme E2, catalytic domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	UQ_con
CMS3_k127_2882024_6	886293.Sinac_1730	6.504e-25	118.0	COG1310@1|root,COG1310@2|Bacteria,2IZZW@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Mov34 MPN PAD-1 family	-	-	-	-	-	-	-	-	-	-	-	-	JAB
CMS3_k127_2882024_7	1196322.A370_00423	1.196e-23	114.0	COG1310@1|root,COG1310@2|Bacteria,1VQJE@1239|Firmicutes,24CU8@186801|Clostridia	186801|Clostridia	S	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	-	-	-	-	-	-	-	-	-	-	-	-	JAB,LysM
CMS3_k127_2882024_9	1408324.JNJK01000013_gene64	1.174e-07	59.0	2E0TS@1|root,32WBE@2|Bacteria,1VBFI@1239|Firmicutes,24M0A@186801|Clostridia	186801|Clostridia	S	Prokaryotic RING finger family 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2628,Prok-RING_1,zinc_ribbon_2
CMS3_k127_2882024_1	926550.CLDAP_34420	7.301e-99	340.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi	200795|Chloroflexi	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_2882024_0	926550.CLDAP_34410	1.977e-101	347.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi	200795|Chloroflexi	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_2882024_4	1128421.JAGA01000003_gene3050	4.816e-39	153.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
CMS3_k127_2882024_2	411467.BACCAP_03070	5.162e-89	312.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,267N2@186813|unclassified Clostridiales	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_2882024_3	395493.BegalDRAFT_3427	1.364e-88	299.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS3_k127_2882463_0	562970.Btus_1805	7.008e-135	447.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,2784J@186823|Alicyclobacillaceae	91061|Bacilli	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_2884978_0	357808.RoseRS_0270	6.965e-97	333.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_2884978_1	321327.CYA_2243	5.771e-47	177.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1H1NJ@1129|Synechococcus	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS3_k127_288540_0	1499967.BAYZ01000052_gene4665	8.601e-138	479.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_2887152_1	926550.CLDAP_16140	3.391e-98	330.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
CMS3_k127_2887152_0	926569.ANT_21050	4.026e-233	738.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
CMS3_k127_2887152_3	644282.Deba_3134	2.276e-21	97.0	COG1028@1|root,COG2030@1|root,COG3255@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,COG3255@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas,SCP2,adh_short
CMS3_k127_2887152_4	237368.SCABRO_01832	2.648e-11	70.0	COG2128@1|root,COG2128@2|Bacteria,2J1AB@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS3_k127_2887152_2	436308.Nmar_1096	6.646e-49	183.0	arCOG09395@1|root,arCOG09395@2157|Archaea,41T04@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS3_k127_2888324_0	1128421.JAGA01000003_gene3718	2.316e-226	718.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_2901906_0	344747.PM8797T_15883	5.014e-79	289.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,2IXUA@203682|Planctomycetes	203682|Planctomycetes	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
CMS3_k127_2901906_2	1120985.AUMI01000016_gene1829	1.006e-50	208.0	COG0251@1|root,COG0251@2|Bacteria,1VT5Z@1239|Firmicutes	1239|Firmicutes	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2901906_1	868595.Desca_0967	1.828e-52	194.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,24BG9@186801|Clostridia,26499@186807|Peptococcaceae	186801|Clostridia	K	response regulator	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
CMS3_k127_2901906_3	1283287.KB822575_gene564	9.296e-23	100.0	COG3275@1|root,COG3275@2|Bacteria,2GJD4@201174|Actinobacteria,4DNZQ@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
CMS3_k127_2910178_4	420324.KI912045_gene4360	2.284e-25	106.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,1JSFG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS3_k127_2910178_5	366602.Caul_1641	1.24e-10	73.0	2DW9D@1|root,33Z5Z@2|Bacteria,1NZ18@1224|Proteobacteria,2UT4F@28211|Alphaproteobacteria,2KJ25@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2910178_2	1120971.AUCA01000039_gene2475	8.104e-67	238.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,278Y6@186823|Alicyclobacillaceae	91061|Bacilli	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_2910178_1	485913.Krac_0163	1.036e-126	427.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi	2|Bacteria	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_2910178_3	926569.ANT_14000	7.027e-41	158.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
CMS3_k127_2910178_0	330214.NIDE3635	2.447e-178	574.0	COG4108@1|root,COG4108@2|Bacteria,3J0WP@40117|Nitrospirae	40117|Nitrospirae	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
CMS3_k127_2910178_6	572547.Amico_1206	6.558e-06	49.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
CMS3_k127_2910178_7	1429851.X548_00860	0.0001088	51.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,1RP4F@1236|Gammaproteobacteria,1X5JE@135614|Xanthomonadales	135614|Xanthomonadales	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
CMS3_k127_2913857_0	926569.ANT_20890	5.725e-227	721.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS3_k127_2913857_1	926550.CLDAP_25230	6.539e-109	376.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
CMS3_k127_2913857_2	653733.Selin_0051	1.376e-34	139.0	COG0019@1|root,COG0019@2|Bacteria	2|Bacteria	E	diaminopimelate decarboxylase activity	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.1.129,3.4.16.4,4.1.1.20	ko:K01586,ko:K05366	ko00300,ko00550,ko01100,ko01110,ko01120,ko01130,ko01230,ko01501,map00300,map00550,map01100,map01110,map01120,map01130,map01230,map01501	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000,ko01003,ko01011	-	GT51	iLJ478.TM1517	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS3_k127_2920194_2	745776.DGo_CA2209	5.704e-14	80.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2920194_1	391625.PPSIR1_35997	3.559e-27	118.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS3_k127_2920194_0	1144319.PMI16_01205	2.233e-30	126.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,4744R@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS3_k127_2931527_1	1121406.JAEX01000002_gene805	1.62e-21	106.0	COG1035@1|root,COG1152@1|root,COG1035@2|Bacteria,COG1152@2|Bacteria,1R4GN@1224|Proteobacteria,42P9J@68525|delta/epsilon subdivisions,2WJ9S@28221|Deltaproteobacteria,2MGKM@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_17,FrhB_FdhB_C
CMS3_k127_2931527_0	457570.Nther_2665	4.234e-207	659.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_2934715_0	316274.Haur_1972	6.064e-170	566.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,DUF4145,Pentapeptide,RDD
CMS3_k127_2934715_4	446471.Xcel_1946	6.997e-05	49.0	2ERBG@1|root,33IX4@2|Bacteria,2GPQE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2934715_3	561175.KB894104_gene1186	8.195e-07	57.0	COG3568@1|root,COG4675@1|root,COG3568@2|Bacteria,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Collar,Exo_endo_phos,Laminin_G_3,Phage_fiber_2
CMS3_k127_2934715_2	365528.KB891240_gene6057	3.998e-13	83.0	COG3568@1|root,COG4675@1|root,COG3568@2|Bacteria,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
CMS3_k127_2934715_1	502558.EGYY_21350	7.642e-19	90.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CUSY@84998|Coriobacteriia	84998|Coriobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_2936004_3	383372.Rcas_1126	1.904e-98	344.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi,37660@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_2936004_2	926550.CLDAP_19400	1.284e-117	393.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_2936004_5	1128421.JAGA01000002_gene895	6.676e-90	303.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
CMS3_k127_2936004_10	765420.OSCT_2271	1.806e-38	162.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8HH@200795|Chloroflexi	200795|Chloroflexi	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS3_k127_2936004_8	926569.ANT_13820	2.083e-67	235.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
CMS3_k127_2936004_4	357808.RoseRS_1236	1.194e-96	325.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,376BU@32061|Chloroflexia	2|Bacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2936004_9	383372.Rcas_3764	2.377e-64	231.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS3_k127_2936004_6	880073.Calab_3513	7.317e-84	293.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	pip	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Peptidase_S9
CMS3_k127_2936004_7	264732.Moth_1558	1.275e-69	246.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,42ES9@68295|Thermoanaerobacterales	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS3_k127_2936004_1	118163.Ple7327_4457	2.427e-132	430.0	COG0667@1|root,COG0667@2|Bacteria,1G1XV@1117|Cyanobacteria,3VIG5@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_2936004_11	1380350.JIAP01000031_gene1046	1.128e-33	152.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,43PM5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Hydrolase_4,Trans_reg_C
CMS3_k127_2936004_0	98439.AJLL01000052_gene3650	8.879e-216	719.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,1FZVW@1117|Cyanobacteria,1JHHT@1189|Stigonemataceae	1117|Cyanobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pentapeptide,WD40
CMS3_k127_2936735_3	324602.Caur_3179	1.921e-05	53.0	COG1572@1|root,COG4932@1|root,COG1572@2|Bacteria,COG4932@2|Bacteria,2GBU0@200795|Chloroflexi,376QE@32061|Chloroflexia	32061|Chloroflexia	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
CMS3_k127_2936735_1	1414720.CBYM010000003_gene404	1.678e-24	107.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,36M0F@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
CMS3_k127_2936735_0	1173027.Mic7113_0495	4.626e-68	239.0	COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria,1HAKG@1150|Oscillatoriales	1117|Cyanobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2936735_2	118173.KB235914_gene1451	4.653e-14	81.0	COG3858@1|root,COG3858@2|Bacteria	2|Bacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,PepSY,RicinB_lectin_2,Ricin_B_lectin,SLH
CMS3_k127_2940460_0	485913.Krac_6991	8.188e-120	411.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_2940460_1	485913.Krac_6031	8.827e-46	169.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2944410_6	765420.OSCT_2557	5.596e-54	198.0	COG1100@1|root,COG1100@2|Bacteria,2G6A7@200795|Chloroflexi,37523@32061|Chloroflexia	2|Bacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
CMS3_k127_2944410_13	324602.Caur_2319	2.624e-18	95.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,Robl_LC7
CMS3_k127_2944410_7	1128421.JAGA01000001_gene2388	1.698e-38	154.0	COG0745@1|root,COG0745@2|Bacteria	1128421.JAGA01000001_gene2388|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2944410_4	864702.OsccyDRAFT_0416	3.357e-66	258.0	COG0642@1|root,COG2203@1|root,COG3707@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3707@2|Bacteria,1G09B@1117|Cyanobacteria,1H97F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
CMS3_k127_2944410_5	686340.Metal_0396	1.827e-58	233.0	COG0642@1|root,COG2202@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_4,PAS_9,dCache_2
CMS3_k127_2944410_9	156889.Mmc1_0770	1.243e-29	138.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	luxQ	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	2.7.13.3	ko:K07678,ko:K10909	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	M00475,M00513	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,LuxQ-periplasm,PAS,PAS_3,PAS_9,Response_reg,dCache_1
CMS3_k127_2944410_8	1463856.JOHY01000013_gene6204	2.545e-36	158.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
CMS3_k127_2944410_3	42256.RradSPS_2942	3.641e-107	372.0	COG1269@1|root,COG1269@2|Bacteria,2I9VH@201174|Actinobacteria	201174|Actinobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
CMS3_k127_2944410_12	593750.Metfor_0254	6.789e-19	88.0	COG0636@1|root,arCOG02455@2157|Archaea,2Y4F6@28890|Euryarchaeota,2NB8I@224756|Methanomicrobia	224756|Methanomicrobia	C	ATP synthase subunit C	atpK-2	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
CMS3_k127_2944410_11	649638.Trad_2020	4.803e-21	105.0	COG1527@1|root,COG1527@2|Bacteria,1WIV8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
CMS3_k127_2944410_14	42256.RradSPS_2938	3.845e-07	56.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
CMS3_k127_2944410_1	304371.MCP_2290	6.571e-200	642.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,2NANC@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA-2	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
CMS3_k127_2944410_2	323259.Mhun_1758	1.967e-174	578.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_2944410_10	42256.RradSPS_2944	4.469e-26	115.0	COG1394@1|root,COG1394@2|Bacteria	2|Bacteria	C	ATPase activity, coupled to transmembrane movement of substances	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
CMS3_k127_2944410_0	1321778.HMPREF1982_00104	9.394e-246	776.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,268EA@186813|unclassified Clostridiales	186801|Clostridia	G	Firmicute fructose-1,6-bisphosphatase	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
CMS3_k127_2946913_1	635013.TherJR_2841	2.902e-05	50.0	COG5542@1|root,COG5542@2|Bacteria,1V7KR@1239|Firmicutes,24IW1@186801|Clostridia,262FJ@186807|Peptococcaceae	186801|Clostridia	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
CMS3_k127_2946913_3	2340.JV46_23700	8.039e-05	50.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1J6UZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	DJ-1/PfpI family	thiJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS3_k127_2946913_0	118168.MC7420_4881	8.806e-12	79.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pentapeptide,WD40
CMS3_k127_2946913_2	318161.Sden_3374	3.477e-05	54.0	COG1595@1|root,COG1595@2|Bacteria,1RHRR@1224|Proteobacteria,1S2UD@1236|Gammaproteobacteria,2QBGA@267890|Shewanellaceae	1236|Gammaproteobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	sigY	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2951112_2	203124.Tery_3858	4.387e-77	270.0	COG2211@1|root,COG2211@2|Bacteria,1G0ZY@1117|Cyanobacteria,1H6Y4@1150|Oscillatoriales	1117|Cyanobacteria	G	COG2211 Na melibiose symporter and related	melB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS3_k127_2951112_0	485913.Krac_8864	7.753e-84	286.0	COG2521@1|root,COG2521@2|Bacteria,2G7RX@200795|Chloroflexi	200795|Chloroflexi	S	Methyltransferase domain	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_11
CMS3_k127_2951112_1	1156844.KB891820_gene435	2.49e-79	302.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	bpr	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Malectin,PKD,Peptidase_M6,Peptidase_S8
CMS3_k127_2951112_3	515635.Dtur_0603	2.081e-11	79.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,FlgD_ig,Peptidase_M6
CMS3_k127_2951112_4	926560.KE387027_gene277	1.476e-05	59.0	COG1404@1|root,COG3828@1|root,COG1404@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	3.4.21.62	ko:K01342,ko:K12287,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02044,ko03110	-	-	-	FG-GAP,PPC,Peptidase_C2,Peptidase_S8,VCBS
CMS3_k127_2975549_0	329726.AM1_2452	1.219e-206	670.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_2975549_2	469382.Hbor_06150	1.036e-31	131.0	COG0500@1|root,arCOG03411@2157|Archaea,2XWTI@28890|Euryarchaeota,23VGG@183963|Halobacteria	183963|Halobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS3_k127_2975549_1	246197.MXAN_2463	4.59e-50	200.0	COG4789@1|root,COG4789@2|Bacteria,1R346@1224|Proteobacteria,43DIZ@68525|delta/epsilon subdivisions,2X8Q9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type III secretion protein	-	-	-	ko:K03230	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	FHIPEP
CMS3_k127_2975549_3	483219.LILAB_20000	1.441e-27	128.0	COG4789@1|root,COG4789@2|Bacteria,1R346@1224|Proteobacteria,43DIZ@68525|delta/epsilon subdivisions,2X8Q9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type III secretion protein	-	-	-	ko:K03230	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	FHIPEP
CMS3_k127_2976710_5	222534.KB893705_gene5921	2.429e-08	57.0	COG0664@1|root,COG1225@1|root,COG1994@1|root,COG0664@2|Bacteria,COG1225@2|Bacteria,COG1994@2|Bacteria,2IBWH@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase M50	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	AhpC-TSA,FHA,Yop-YscD_cpl,cNMP_binding
CMS3_k127_2976710_2	1000565.METUNv1_03440	4.986e-26	115.0	COG1670@1|root,COG1670@2|Bacteria,1PZTX@1224|Proteobacteria,2W4BT@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_2976710_4	235985.BBPN01000050_gene8396	6.911e-12	67.0	2EM92@1|root,33EY7@2|Bacteria,2GS4K@201174|Actinobacteria,2NJWX@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2976710_1	1122179.KB890423_gene2354	9.778e-35	138.0	COG0062@1|root,COG0062@2|Bacteria,4P050@976|Bacteroidetes	976|Bacteroidetes	G	YjeF-related protein N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	YjeF_N
CMS3_k127_2976710_3	1117318.PRUB_01169	1.523e-20	97.0	COG5031@1|root,COG5031@2|Bacteria,1P4JV@1224|Proteobacteria,1SUJM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2985441_0	926569.ANT_10850	6.529e-139	481.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636,ko:K07642	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
CMS3_k127_2985441_6	926569.ANT_13990	2.609e-48	187.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_2985441_4	1089553.Tph_c00330	1.117e-88	303.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,42F5R@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_2985441_5	926550.CLDAP_04310	4.509e-81	278.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_2985441_3	1128421.JAGA01000002_gene786	1.668e-91	308.0	COG0024@1|root,COG0024@2|Bacteria,2NP57@2323|unclassified Bacteria	2|Bacteria	J	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
CMS3_k127_2985441_2	926550.CLDAP_06530	2.096e-126	415.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CMS3_k127_2985441_1	326427.Cagg_1321	4.403e-136	451.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_2985441_8	926550.CLDAP_21910	6.379e-36	139.0	COG3631@1|root,COG3631@2|Bacteria,2G75M@200795|Chloroflexi	200795|Chloroflexi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_2985441_10	450851.PHZ_c2869	1.306e-08	65.0	COG1266@1|root,COG1266@2|Bacteria,1NXKQ@1224|Proteobacteria	1224|Proteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2985441_9	629265.PMA4326_05995	5.189e-17	87.0	COG0454@1|root,COG0456@2|Bacteria,1NMEA@1224|Proteobacteria,1T33V@1236|Gammaproteobacteria,1ZA1E@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS3_k127_2985441_7	1218075.BAYA01000004_gene1327	3.432e-36	144.0	COG1280@1|root,COG1280@2|Bacteria,1MX0K@1224|Proteobacteria,2VVQ0@28216|Betaproteobacteria,1KGSA@119060|Burkholderiaceae	28216|Betaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS3_k127_2993990_8	1472418.BBJC01000001_gene715	1.265e-06	51.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	soxA2	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS3_k127_2993990_7	28042.GU90_10335	1.6e-22	99.0	COG4311@1|root,COG4311@2|Bacteria,2IQIZ@201174|Actinobacteria,4E5CD@85010|Pseudonocardiales	201174|Actinobacteria	E	Sarcosine oxidase, delta subunit family	soxD	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
CMS3_k127_2993990_2	1123023.JIAI01000007_gene1965	2.163e-195	616.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4EEMB@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_2993990_4	926550.CLDAP_19800	1.151e-73	256.0	28I8Y@1|root,2Z8BR@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
CMS3_k127_2993990_9	661478.OP10G_4576	0.0001834	50.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_2993990_5	1463900.JOIX01000002_gene5212	2.648e-41	161.0	COG1802@1|root,COG1802@2|Bacteria,2HS3R@201174|Actinobacteria	201174|Actinobacteria	K	gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS3_k127_2993990_1	926550.CLDAP_37920	6.262e-200	634.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	mttB2	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS3_k127_2993990_0	43354.JOIJ01000002_gene4227	0.0	1144.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E1F5@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS3_k127_2993990_3	797304.Natgr_2922	4.275e-79	271.0	COG2086@1|root,arCOG00446@2157|Archaea,2XW02@28890|Euryarchaeota,23TZ0@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein, beta subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_2993990_6	797304.Natgr_2923	1.932e-25	113.0	COG2025@1|root,arCOG00447@2157|Archaea,2XUIS@28890|Euryarchaeota,23T9A@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS3_k127_2997225_1	1454202.PPBDW_100228___1	4.061e-12	79.0	COG1361@1|root,COG1404@1|root,COG2304@1|root,COG3210@1|root,COG3291@1|root,COG3292@1|root,COG3391@1|root,COG4547@1|root,COG4719@1|root,COG4932@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG2304@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3292@2|Bacteria,COG3391@2|Bacteria,COG4547@2|Bacteria,COG4719@2|Bacteria,COG4932@2|Bacteria,1R59C@1224|Proteobacteria,1SDEC@1236|Gammaproteobacteria,1XWCY@135623|Vibrionales	1236|Gammaproteobacteria	MOT	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS3_k127_2997225_2	163908.KB235896_gene3939	1.141e-05	57.0	COG4932@1|root,COG4932@2|Bacteria,1GIGN@1117|Cyanobacteria,1HKKY@1161|Nostocales	1117|Cyanobacteria	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS3_k127_3003618_1	357808.RoseRS_2782	8.353e-33	136.0	COG0500@1|root,COG2226@2|Bacteria,2G724@200795|Chloroflexi,377H0@32061|Chloroflexia	32061|Chloroflexia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_3003618_2	867903.ThesuDRAFT_01639	7.208e-26	118.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WDCK@538999|Clostridiales incertae sedis	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_3003618_0	926550.CLDAP_29280	1.083e-91	310.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_3006928_0	102129.Lepto7375DRAFT_0506	1.974e-116	392.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_3018948_11	765912.Thimo_3569	2.767e-08	64.0	COG1216@1|root,COG1216@2|Bacteria,1N5RX@1224|Proteobacteria,1SH90@1236|Gammaproteobacteria,1WZUQ@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS3_k127_3018948_5	1227457.C451_20617	2.313e-54	206.0	COG0438@1|root,arCOG01403@2157|Archaea,2Y0NE@28890|Euryarchaeota,241CI@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_3018948_3	1303518.CCALI_00571	5.265e-64	228.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3018948_9	401053.AciPR4_2616	8.271e-21	104.0	COG1493@1|root,COG1493@2|Bacteria,3Y4YI@57723|Acidobacteria,2JK5E@204432|Acidobacteriia	204432|Acidobacteriia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3018948_8	1380356.JNIK01000004_gene139	4.437e-22	111.0	COG1287@1|root,COG1287@2|Bacteria,2GWXZ@201174|Actinobacteria	201174|Actinobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3018948_1	1163409.UUA_18047	3.557e-79	273.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K16048	ko00984,ko01100,map00984,map01100	-	R09819	RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct,Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_3018948_10	401526.TcarDRAFT_1702	1.485e-11	76.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,4H249@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
CMS3_k127_3018948_2	706587.Desti_3666	6.763e-75	261.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42SZT@68525|delta/epsilon subdivisions,2WPXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_3018948_0	111780.Sta7437_1464	1.631e-79	274.0	COG1922@1|root,COG1922@2|Bacteria,1G0K7@1117|Cyanobacteria,3VKB0@52604|Pleurocapsales	1117|Cyanobacteria	M	TIGRFAM bacterial polymer biosynthesis proteins, WecB TagA CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
CMS3_k127_3018948_7	383372.Rcas_3106	4.233e-48	187.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3018948_6	671143.DAMO_0905	1.326e-51	196.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3018948_4	404380.Gbem_0853	3.071e-61	224.0	COG0438@1|root,COG0438@2|Bacteria,1PEGM@1224|Proteobacteria,43AEB@68525|delta/epsilon subdivisions,2X5U6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3025554_0	926550.CLDAP_17770	1.534e-202	637.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS3_k127_3025554_2	316274.Haur_3260	5.006e-97	323.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi,375AJ@32061|Chloroflexia	32061|Chloroflexia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_3025554_5	926569.ANT_08510	4.345e-45	170.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
CMS3_k127_3025554_3	926569.ANT_17280	1.156e-83	285.0	COG1028@1|root,COG1028@2|Bacteria,2G8P1@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_3025554_1	926550.CLDAP_09300	8.09e-107	357.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
CMS3_k127_3025554_4	926550.CLDAP_37690	1.852e-70	249.0	COG1898@1|root,COG1898@2|Bacteria,2G7AS@200795|Chloroflexi	200795|Chloroflexi	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS3_k127_3025554_6	926569.ANT_14320	9.257e-29	120.0	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS3_k127_3032248_2	926569.ANT_26890	1.547e-22	108.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_3032248_0	1114856.C496_19525	3.185e-76	266.0	COG2897@1|root,arCOG02019@2157|Archaea,2XW8Q@28890|Euryarchaeota,23UHH@183963|Halobacteria	183963|Halobacteria	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS3_k127_3032248_1	485913.Krac_5098	2.977e-40	152.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS3_k127_3037087_4	1449351.RISW2_10025	1.252e-88	299.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	attM	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_3037087_3	391589.RGAI101_2570	3.75e-151	486.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2U22H@28211|Alphaproteobacteria,2P4ID@2433|Roseobacter	28211|Alphaproteobacteria	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_3037087_8	649638.Trad_1325	6.149e-24	109.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	rsmD	-	2.1.1.171	ko:K08316,ko:K15257	-	-	R07234	RC00003	ko00000,ko01000,ko03009,ko03016	-	-	-	Cons_hypoth95
CMS3_k127_3037087_6	388467.A19Y_2394	1.006e-31	142.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1G0TA@1117|Cyanobacteria,1H8GU@1150|Oscillatoriales	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2,TPR_19
CMS3_k127_3037087_9	368407.Memar_0351	1.055e-23	105.0	COG1917@1|root,arCOG03004@2157|Archaea,2XYUR@28890|Euryarchaeota,2NB2H@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_3037087_7	391625.PPSIR1_25371	1.029e-25	114.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,42PP6@68525|delta/epsilon subdivisions,2WJN2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
CMS3_k127_3037087_12	1123073.KB899241_gene2311	7.428e-07	58.0	2DWEZ@1|root,33ZZS@2|Bacteria,1NYBC@1224|Proteobacteria,1SQSQ@1236|Gammaproteobacteria,1XAUU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3037087_11	1210884.HG799469_gene14100	1.512e-19	95.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS3_k127_3037087_5	395493.BegalDRAFT_0269	4.053e-56	209.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,1T4BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,Response_reg
CMS3_k127_3037087_0	196490.AUEZ01000042_gene7227	0.0	1141.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_3037087_1	926569.ANT_05680	8.955e-267	831.0	COG1878@1|root,COG1878@2|Bacteria,2G8DE@200795|Chloroflexi	2|Bacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS3_k127_3037087_2	926569.ANT_05670	1.485e-189	599.0	COG0074@1|root,COG0074@2|Bacteria,2G7UI@200795|Chloroflexi	200795|Chloroflexi	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
CMS3_k127_3037087_10	1121413.JMKT01000011_gene2381	1.682e-21	96.0	COG4284@1|root,COG4284@2|Bacteria,1Q5YI@1224|Proteobacteria,42QK5@68525|delta/epsilon subdivisions,2WKKW@28221|Deltaproteobacteria,2M92E@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS3_k127_3042670_4	69395.JQLZ01000007_gene1746	1.179e-05	52.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,1QVGM@1224|Proteobacteria,2TWFQ@28211|Alphaproteobacteria,2KJS0@204458|Caulobacterales	204458|Caulobacterales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS3_k127_3042670_0	1380356.JNIK01000018_gene848	4.734e-41	167.0	2E9HK@1|root,333QQ@2|Bacteria,2I89Z@201174|Actinobacteria,4ETI2@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3042670_2	450851.PHZ_c2319	8.971e-22	99.0	COG2050@1|root,COG2050@2|Bacteria,1RBET@1224|Proteobacteria,2U5TM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	MA20_42425	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_3042670_3	383372.Rcas_0309	7.1e-20	94.0	2EJQK@1|root,33DFE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3042670_1	1480694.DC28_05675	1.618e-37	141.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_3052598_4	443143.GM18_0071	2.35e-32	132.0	COG2199@1|root,COG3706@2|Bacteria,1PBPS@1224|Proteobacteria	1224|Proteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HDOD
CMS3_k127_3052598_1	443143.GM18_0072	3.926e-62	223.0	COG2204@1|root,COG2204@2|Bacteria,1QWDW@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_3052598_2	1121918.ARWE01000001_gene3198	1.415e-57	221.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43DFM@68525|delta/epsilon subdivisions,2X8MI@28221|Deltaproteobacteria,43UST@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_3052598_3	1121918.ARWE01000001_gene3199	1.561e-49	203.0	COG2199@1|root,COG2202@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_3052598_5	314230.DSM3645_17555	3.386e-15	91.0	COG0642@1|root,COG0642@2|Bacteria,2J529@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_3052598_0	309800.C498_17770	1.679e-69	243.0	COG1028@1|root,arCOG01259@2157|Archaea,2XUNT@28890|Euryarchaeota,23U46@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_3052598_6	1449357.JQLK01000001_gene1693	2.911e-07	56.0	2DSVR@1|root,33HKS@2|Bacteria,1WKIU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3,RHH_4
CMS3_k127_3052598_7	449447.MAE_32560	3.23e-05	51.0	COG2402@1|root,COG2402@2|Bacteria,1G8EG@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3058041_2	1379270.AUXF01000001_gene2571	6.585e-31	130.0	COG1986@1|root,COG1986@2|Bacteria,1ZUVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
CMS3_k127_3058041_3	1192034.CAP_8702	3.905e-18	91.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,432MH@68525|delta/epsilon subdivisions,2WYFU@28221|Deltaproteobacteria,2YVDK@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_3058041_0	1519464.HY22_02590	6.799e-58	210.0	COG0351@1|root,COG0351@2|Bacteria,1FDU5@1090|Chlorobi	1090|Chlorobi	H	PFAM Phosphomethylpyrimidine kinase type-1	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS3_k127_3058041_1	326427.Cagg_1254	6.649e-51	193.0	COG0354@1|root,COG0354@2|Bacteria,2G8ZM@200795|Chloroflexi,375KW@32061|Chloroflexia	32061|Chloroflexia	S	Aminomethyltransferase folate-binding domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS3_k127_3058349_5	37659.JNLN01000001_gene2778	1.336e-21	100.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia,36N4Z@31979|Clostridiaceae	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS3_k127_3058349_6	56110.Oscil6304_1612	1.114e-11	70.0	COG0762@1|root,COG0762@2|Bacteria,1G9UC@1117|Cyanobacteria,1HCV0@1150|Oscillatoriales	1117|Cyanobacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
CMS3_k127_3058349_1	326427.Cagg_0341	1.298e-49	198.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_3058349_2	1396418.BATQ01000046_gene6100	3.059e-48	180.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,2IUI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_3058349_4	177437.HRM2_24220	2.635e-25	109.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_3058349_0	926550.CLDAP_27990	1.285e-91	317.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_3058349_3	886293.Sinac_3646	1.718e-40	154.0	2B1QU@1|root,31U6H@2|Bacteria,2J3AT@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
CMS3_k127_3058980_8	1336243.JAEA01000011_gene3180	1.593e-09	59.0	COG1309@1|root,COG1309@2|Bacteria,1RKMF@1224|Proteobacteria,2UAP3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WHG
CMS3_k127_3058980_1	314282.PCNPT3_07740	3.242e-84	292.0	COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,1RYBI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS3_k127_3058980_2	762903.Pedsa_2409	9.912e-56	205.0	COG2911@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,4NHHA@976|Bacteroidetes	976|Bacteroidetes	E	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3
CMS3_k127_3058980_6	983917.RGE_04270	1.389e-37	153.0	COG1215@1|root,COG1215@2|Bacteria,1PFW5@1224|Proteobacteria,2W9RS@28216|Betaproteobacteria,1KP6N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_3058980_4	243231.GSU2250	2.745e-42	173.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3058980_7	356851.JOAN01000020_gene4014	3.65e-31	136.0	COG1216@1|root,COG1216@2|Bacteria,2I5Z7@201174|Actinobacteria,4DFNY@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_2
CMS3_k127_3058980_3	383372.Rcas_1700	5.71e-50	203.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi,376TX@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3058980_0	1137281.D778_02055	3.748e-148	489.0	COG3227@1|root,COG3291@1|root,COG4935@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4NQ5Q@976|Bacteroidetes	976|Bacteroidetes	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,PepSY,Peptidase_M36,Peptidase_M4
CMS3_k127_3058980_5	765420.OSCT_0624	4.162e-42	159.0	COG0664@1|root,COG1234@1|root,COG0664@2|Bacteria,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	MA20_22080	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Lactamase_B_2,TIR-like,cNMP_binding
CMS3_k127_3060980_0	316274.Haur_4444	7.08e-198	628.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi,3758Q@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_3066092_14	426114.THI_2200	8.827e-08	63.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,1KKJ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
CMS3_k127_3066092_12	497964.CfE428DRAFT_0215	5.109e-10	70.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
CMS3_k127_3066092_2	56107.Cylst_0777	1.651e-41	160.0	COG4339@1|root,COG4339@2|Bacteria,1G5Q9@1117|Cyanobacteria,1HJAE@1161|Nostocales	1117|Cyanobacteria	S	COGs COG4339 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3066092_11	935866.JAER01000012_gene3466	3.608e-12	76.0	COG0668@1|root,COG0668@2|Bacteria,2HD92@201174|Actinobacteria,4DRXH@85009|Propionibacteriales	201174|Actinobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
CMS3_k127_3066092_8	1382306.JNIM01000001_gene2997	3.237e-25	114.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088,ko:K07263	-	-	-	-	ko00000,ko01000,ko01002,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3066092_0	56780.SYN_02631	1.83e-111	377.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,42XYJ@68525|delta/epsilon subdivisions,2WSKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
CMS3_k127_3066092_3	326427.Cagg_0604	1.059e-34	152.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GABQ@200795|Chloroflexi,3751C@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HATPase_c,HisKA,PAS_4
CMS3_k127_3066092_1	926550.CLDAP_20290	1.689e-49	180.0	COG0346@1|root,COG0346@2|Bacteria,2G8UR@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_3066092_10	1487953.JMKF01000021_gene2189	6.938e-18	95.0	COG0824@1|root,COG0824@2|Bacteria,1G6JT@1117|Cyanobacteria,1HBX0@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
CMS3_k127_3066092_9	1173025.GEI7407_3834	8.045e-23	110.0	COG0824@1|root,COG0824@2|Bacteria,1G6JT@1117|Cyanobacteria,1HBX0@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
CMS3_k127_3066092_4	861299.J421_6257	1.344e-34	144.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	yyaK	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_3066092_7	1150399.AQYK01000002_gene3710	2.438e-26	112.0	COG4319@1|root,COG4319@2|Bacteria,2IRNE@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_3066092_15	1128421.JAGA01000002_gene1598	4.959e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3066092_6	292459.STH2528	2.644e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,1VD37@1239|Firmicutes,25BCE@186801|Clostridia	186801|Clostridia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_3066092_5	103690.17130136	5.131e-31	132.0	COG2931@1|root,COG2931@2|Bacteria,1G4X1@1117|Cyanobacteria,1HTX8@1161|Nostocales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind
CMS3_k127_308224_0	937777.Deipe_3255	1.514e-104	348.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_308224_1	926550.CLDAP_13920	8.582e-65	227.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS3_k127_308224_2	414684.RC1_2846	6.495e-05	53.0	2EPPM@1|root,33HA6@2|Bacteria,1NIZ1@1224|Proteobacteria,2UNKA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3084949_0	402777.KB235898_gene5555	4.285e-203	661.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding,PilZ
CMS3_k127_3084949_1	1485545.JQLW01000008_gene1984	4.085e-39	158.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria	1224|Proteobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_3084949_2	1485545.JQLW01000008_gene1984	3.583e-38	155.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria	1224|Proteobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_3084949_3	388467.A19Y_0614	1.814e-26	114.0	COG0615@1|root,COG0615@2|Bacteria,1G1YM@1117|Cyanobacteria,1HHMP@1150|Oscillatoriales	1117|Cyanobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_3101695_3	479434.Sthe_1800	1.169e-73	264.0	COG0373@1|root,COG0373@2|Bacteria,2G5T4@200795|Chloroflexi,27YFY@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_3101695_5	765420.OSCT_0897	8.678e-46	172.0	COG0789@1|root,COG0789@2|Bacteria,2GBIN@200795|Chloroflexi,375XH@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS3_k127_3101695_1	717605.Theco_3404	1.252e-129	441.0	COG4188@1|root,COG4188@2|Bacteria,1UGK7@1239|Firmicutes,4HCXS@91061|Bacilli,275EF@186822|Paenibacillaceae	91061|Bacilli	S	Chlorophyllase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
CMS3_k127_3101695_4	338963.Pcar_0302	2.276e-54	199.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,43SFN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
CMS3_k127_3101695_6	349521.HCH_06592	1.161e-26	117.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_3101695_2	926550.CLDAP_28630	2.109e-124	408.0	COG0044@1|root,COG0044@2|Bacteria,2G640@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS3_k127_3101695_0	1128421.JAGA01000003_gene3014	6.111e-144	462.0	COG0540@1|root,COG0540@2|Bacteria,2NNPZ@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5856	OTCace,OTCace_N
CMS3_k127_3103630_3	313624.NSP_5230	9.169e-39	146.0	COG4680@1|root,COG4680@2|Bacteria,1G7BW@1117|Cyanobacteria,1HPS5@1161|Nostocales	1117|Cyanobacteria	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
CMS3_k127_3103630_2	671143.DAMO_3092	2.736e-43	161.0	COG5499@1|root,COG5499@2|Bacteria,2NRMJ@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
CMS3_k127_3103630_0	118168.MC7420_1971	4.847e-46	174.0	2B3PJ@1|root,31WD1@2|Bacteria,1G6XS@1117|Cyanobacteria,1HD98@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3103630_4	300852.55771538	1.003e-11	68.0	COG1846@1|root,COG1846@2|Bacteria,1WKGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
CMS3_k127_3103630_1	999541.bgla_1g20590	1.414e-43	167.0	COG3340@1|root,COG3340@2|Bacteria,1N554@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
CMS3_k127_3103630_5	208444.JNYY01000006_gene6882	1.305e-07	62.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria,4E30Q@85010|Pseudonocardiales	201174|Actinobacteria	Q	N-acetyltransferase	-	-	2.3.1.118	ko:K00675,ko:K15466	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001,ko01000,ko01008	-	-	-	Acetyltransf_2
CMS3_k127_3104494_0	997346.HMPREF9374_3675	3.521e-194	617.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,4HAPE@91061|Bacilli,27BM2@186824|Thermoactinomycetaceae	91061|Bacilli	E	Carboxypeptidase Taq (M32) metallopeptidase	ypwA	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
CMS3_k127_3104494_1	926569.ANT_07040	1.828e-118	390.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179,ko:K01269	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
CMS3_k127_3114167_0	1121946.AUAX01000017_gene4915	6.234e-149	508.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS3_k127_3114167_3	1122182.KB903817_gene1806	7.291e-05	53.0	2BGC7@1|root,32A9Y@2|Bacteria,2GY1H@201174|Actinobacteria,4DGP5@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3114167_1	926569.ANT_12970	1.09e-99	334.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS3_k127_3123652_10	926560.KE387027_gene820	9.839e-06	52.0	COG1167@1|root,COG1167@2|Bacteria,1WM9Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
CMS3_k127_3123652_7	509191.AEDB02000094_gene4210	2.264e-21	103.0	COG5418@1|root,COG5418@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
CMS3_k127_3123652_5	1123276.KB893262_gene4037	1.431e-42	173.0	COG1090@1|root,COG1090@2|Bacteria	2|Bacteria	S	coenzyme binding	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Lipocalin_2,NAD_binding_10
CMS3_k127_3123652_0	1120949.KB903329_gene9217	1.336e-90	331.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
CMS3_k127_3123652_2	526225.Gobs_3758	2.135e-70	250.0	COG2070@1|root,COG2070@2|Bacteria,2IN9Q@201174|Actinobacteria,4EX7F@85013|Frankiales	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_3123652_1	760192.Halhy_1193	3.373e-74	260.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,1IXTS@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_3123652_6	504472.Slin_2185	3.75e-24	102.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,47UCC@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS3_k127_3123652_4	406124.ACPC01000043_gene1820	4.418e-51	192.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
CMS3_k127_3123652_9	196162.Noca_4919	2.315e-17	85.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria,4DR5V@85009|Propionibacteriales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_3123652_3	335283.Neut_1059	1.173e-65	233.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2VH8H@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_3123652_8	234267.Acid_3232	2.059e-17	84.0	29WUM@1|root,30IG2@2|Bacteria,3Y90X@57723|Acidobacteria	57723|Acidobacteria	S	Putative mono-oxygenase ydhR	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
CMS3_k127_3124622_0	357808.RoseRS_2229	3.042e-78	276.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3124622_2	1237149.C900_04988	2.068e-09	59.0	COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CMS3_k127_3124622_1	383372.Rcas_2811	2.56e-43	171.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1,3.2.1.50	ko:K01205,ko:K07004,ko:K12132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko04147	-	-	-	DUF3662,DUF916,FHA,NAGLU,NAGLU_C,NAGLU_N,Yop-YscD_cpl
CMS3_k127_3133466_6	1089550.ATTH01000001_gene1586	5.017e-69	241.0	COG4221@1|root,COG4221@2|Bacteria,4NTKP@976|Bacteroidetes	976|Bacteroidetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3133466_0	429009.Adeg_0177	5.697e-194	631.0	COG1067@1|root,COG1674@1|root,COG1067@2|Bacteria,COG1674@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,42FSR@68295|Thermoanaerobacterales	186801|Clostridia	O	Endopeptidase La	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
CMS3_k127_3133466_3	243164.DET0911	4.384e-118	391.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,34CT4@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_3133466_13	593117.TGAM_0113	0.0001028	54.0	COG1107@1|root,arCOG03400@1|root,arCOG00429@2157|Archaea,arCOG03400@2157|Archaea,2Y6PV@28890|Euryarchaeota,24516@183968|Thermococci	183968|Thermococci	L	COG1107 Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3133466_4	1521187.JPIM01000105_gene265	5.628e-111	366.0	COG0123@1|root,COG0123@2|Bacteria,2G89I@200795|Chloroflexi,376ST@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS3_k127_3133466_2	1382315.JPOI01000001_gene308	9.428e-119	405.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1WFHP@129337|Geobacillus	91061|Bacilli	G	Alpha amylase, N-terminal ig-like domain	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N,Malt_amylase_C
CMS3_k127_3133466_7	1385935.N836_15305	6.77e-69	237.0	293MU@1|root,2ZR3M@2|Bacteria,1G5DA@1117|Cyanobacteria,1HAY6@1150|Oscillatoriales	1117|Cyanobacteria	S	Nickel-containing superoxide dismutase	sodN	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
CMS3_k127_3133466_10	1541065.JRFE01000013_gene2895	5.537e-29	119.0	COG0681@1|root,COG0681@2|Bacteria,1GA6F@1117|Cyanobacteria,3VKBB@52604|Pleurocapsales	1117|Cyanobacteria	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
CMS3_k127_3133466_9	926569.ANT_23780	1.301e-39	164.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
CMS3_k127_3133466_12	1048983.EL17_10210	5.773e-08	61.0	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,47Q6M@768503|Cytophagia	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
CMS3_k127_3133466_11	1157490.EL26_09975	4.644e-25	114.0	arCOG03622@1|root,33HZF@2|Bacteria,1VIHT@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3133466_5	394.NGR_c21180	1.905e-76	270.0	COG0665@1|root,COG0665@2|Bacteria,1R652@1224|Proteobacteria,2U1Q6@28211|Alphaproteobacteria,4BN2T@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_3133466_8	864069.MicloDRAFT_00046540	4.79e-47	177.0	COG2323@1|root,COG2323@2|Bacteria,1PKVB@1224|Proteobacteria,2UZH7@28211|Alphaproteobacteria,1JUD7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
CMS3_k127_3133466_1	926550.CLDAP_16780	6.732e-142	458.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS3_k127_3133877_7	926550.CLDAP_30040	6.062e-84	304.0	COG0642@1|root,COG2205@2|Bacteria	926550.CLDAP_30040|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3133877_8	926550.CLDAP_30050	1.529e-83	284.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_30050|-	T	phosphorelay signal transduction system	-	-	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
CMS3_k127_3133877_4	1128421.JAGA01000003_gene3188	6.404e-96	326.0	COG1283@1|root,COG1283@2|Bacteria	2|Bacteria	P	sodium-dependent phosphate transmembrane transporter activity	-	-	-	ko:K03324,ko:K03466	-	-	-	-	ko00000,ko02000,ko03036	2.A.58.2,3.A.12	-	-	Na_Pi_cotrans,PHO4,PhoU
CMS3_k127_3133877_13	304371.MCP_1966	7.932e-10	69.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,2NB23@224756|Methanomicrobia	224756|Methanomicrobia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
CMS3_k127_3133877_15	797210.Halxa_2499	2.049e-05	55.0	COG0589@1|root,arCOG02053@2157|Archaea,2XX8Y@28890|Euryarchaeota,23VQJ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3133877_16	1220534.B655_1099	0.0008835	45.0	COG4063@1|root,arCOG03221@2157|Archaea,2XWSE@28890|Euryarchaeota,23PC8@183925|Methanobacteria	183925|Methanobacteria	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
CMS3_k127_3133877_14	420247.Msm_1010	1.696e-06	50.0	COG4063@1|root,arCOG03221@2157|Archaea,2XWSE@28890|Euryarchaeota,23PC8@183925|Methanobacteria	183925|Methanobacteria	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
CMS3_k127_3133877_3	1125863.JAFN01000001_gene1547	1.083e-119	400.0	COG1150@1|root,COG2048@1|root,COG1150@2|Bacteria,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	heterodisulfide reductase	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS3_k127_3133877_2	1125863.JAFN01000001_gene1548	2.13e-122	401.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
CMS3_k127_3133877_5	1125863.JAFN01000001_gene1549	2.415e-92	308.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
CMS3_k127_3133877_11	429009.Adeg_0343	2.786e-20	91.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS3_k127_3133877_12	1265505.ATUG01000003_gene623	6.621e-18	89.0	COG1908@1|root,COG1908@2|Bacteria,1RI0K@1224|Proteobacteria,42SSK@68525|delta/epsilon subdivisions,2WPF9@28221|Deltaproteobacteria,2MQ22@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS3_k127_3133877_0	1125863.JAFN01000001_gene1552	0.0	1740.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
CMS3_k127_3133877_10	264732.Moth_1193	1.909e-43	164.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS3_k127_3133877_1	760568.Desku_0188	2.527e-262	843.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885,ko:K16886	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,FlpD,Pyr_redox_2
CMS3_k127_3133877_9	1150600.ADIARSV_3202	3.218e-47	175.0	COG4270@1|root,COG4270@2|Bacteria,4NQEX@976|Bacteroidetes,1ITAE@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CMS3_k127_3133877_6	1077972.ARGLB_058_00620	6.113e-92	312.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class v	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_3142971_0	1200792.AKYF01000019_gene4649	4.672e-91	314.0	COG4552@1|root,COG4552@2|Bacteria,1U5C4@1239|Firmicutes,4HF2I@91061|Bacilli	91061|Bacilli	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
CMS3_k127_3142971_1	1449044.JMLE01000001_gene3985	8.889e-52	193.0	COG0500@1|root,COG2226@2|Bacteria,2HCAN@201174|Actinobacteria,1W9KF@1268|Micrococcaceae	201174|Actinobacteria	Q	Methyltransferase domain	rrmA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_3145812_6	1121124.JNIX01000016_gene2152	1.855e-22	101.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,2KFCF@204458|Caulobacterales	204458|Caulobacterales	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3145812_5	765420.OSCT_2550	3.448e-59	213.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3145812_3	926569.ANT_14280	1.637e-111	374.0	COG0508@1|root,COG0508@2|Bacteria,2G619@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_3145812_0	926569.ANT_14270	4.746e-134	435.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_3145812_1	1382356.JQMP01000003_gene1971	9.463e-115	377.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi,27XY9@189775|Thermomicrobia	189775|Thermomicrobia	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS3_k127_3145812_2	357808.RoseRS_2309	5.364e-113	374.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3145812_4	926569.ANT_01810	9.038e-95	321.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_3155442_12	441620.Mpop_4674	1.557e-18	96.0	COG0451@1|root,COG0451@2|Bacteria,1QP8J@1224|Proteobacteria,2U09V@28211|Alphaproteobacteria,1JUAZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_3155442_8	1459636.NTE_02082	2.469e-64	231.0	COG0834@1|root,arCOG01799@2157|Archaea	2157|Archaea	ET	PFAM Extracellular solute-binding protein, family 3	glnH1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS3_k127_3155442_13	479434.Sthe_3270	4.755e-18	98.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3155442_2	1242864.D187_001830	3.514e-132	467.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS3_k127_3155442_6	765420.OSCT_1574	2.779e-70	272.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_3155442_5	485913.Krac_4592	3.282e-98	339.0	COG1131@1|root,COG1131@2|Bacteria,2G6E6@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG1131 ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_3155442_9	383372.Rcas_2538	6.81e-61	241.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_3155442_14	1120950.KB892746_gene3479	1.745e-09	68.0	COG3806@1|root,COG3806@2|Bacteria	2|Bacteria	T	Anti-sigma factor	-	-	-	ko:K07167	-	-	-	-	ko00000	-	-	-	Cupin_7,zf-HC2
CMS3_k127_3155442_10	485913.Krac_4272	2.25e-41	160.0	COG1595@1|root,COG1595@2|Bacteria,2G9DR@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3155442_0	1121104.AQXH01000005_gene189	3.107e-170	553.0	COG0025@1|root,COG0025@2|Bacteria,4PKJ5@976|Bacteroidetes	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_3155442_11	1177179.A11A3_09465	1.578e-38	147.0	COG2315@1|root,COG2315@2|Bacteria,1N12P@1224|Proteobacteria,1S8W4@1236|Gammaproteobacteria,1XKE8@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS3_k127_3155442_1	497964.CfE428DRAFT_0143	1.607e-138	448.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_3155442_3	357808.RoseRS_2221	2.019e-114	377.0	COG0330@1|root,COG0330@2|Bacteria,2GAHS@200795|Chloroflexi,3767J@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_3155442_7	1242864.D187_008605	2.399e-69	240.0	COG0330@1|root,COG0330@2|Bacteria,1NHZQ@1224|Proteobacteria	1224|Proteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_3155442_4	497964.CfE428DRAFT_0142	5.142e-113	374.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_3155442_16	216594.MMAR_3393	0.0005763	44.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,2374J@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	pmtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_315563_2	1304865.JAGF01000001_gene1172	1.239e-08	62.0	COG2372@1|root,COG2372@2|Bacteria,2HYZZ@201174|Actinobacteria,4F1HZ@85016|Cellulomonadaceae	201174|Actinobacteria	S	CopC domain	-	-	-	-	-	-	-	-	-	-	-	-	CopC
CMS3_k127_315563_1	867845.KI911784_gene2283	1.432e-36	149.0	COG0526@1|root,COG0526@2|Bacteria,2GACV@200795|Chloroflexi,375FU@32061|Chloroflexia	32061|Chloroflexia	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
CMS3_k127_315563_0	794903.OPIT5_04180	1.257e-83	285.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,3K7F5@414999|Opitutae	414999|Opitutae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_3157853_1	926550.CLDAP_14490	1.56e-80	273.0	COG0406@1|root,COG0406@2|Bacteria,2G72Q@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS3_k127_3157853_0	383372.Rcas_2812	2.993e-110	376.0	COG2518@1|root,COG4797@1|root,COG2518@2|Bacteria,COG4797@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	2.1.1.163,2.1.1.201,2.1.1.77	ko:K00573,ko:K03183,ko:K07003	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3560,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
CMS3_k127_3160684_1	1521187.JPIM01000089_gene3263	1.484e-25	118.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS3_k127_3160684_2	867845.KI911784_gene2572	2.884e-18	98.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS3_k127_3160684_0	1385511.N783_07635	3.54e-134	448.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
CMS3_k127_3162208_2	316274.Haur_3520	1.592e-43	162.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,3778H@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS3_k127_3162208_1	926569.ANT_23310	5.089e-87	297.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS3_k127_3162208_0	525904.Tter_1614	4.854e-122	411.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
CMS3_k127_3162208_3	926569.ANT_23340	1.003e-42	162.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_3166352_2	926550.CLDAP_34290	4.108e-05	56.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Big_3_2,Cadherin-like,Calx-beta,DUF11,DUF4347,DUF4430,DUF915,FTP,HYR,I-set,PQQ_2,PT-HINT,Peptidase_M36,Pro-kuma_activ,RHS_repeat,VCBS
CMS3_k127_3166352_1	55601.VANGNB10_cI0808	1.024e-05	58.0	COG1520@1|root,COG1572@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,1QV8R@1224|Proteobacteria,1T2A7@1236|Gammaproteobacteria,1Y33W@135623|Vibrionales	135623|Vibrionales	S	Beta-prism lectin	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,VCBS
CMS3_k127_3166352_0	1089550.ATTH01000001_gene1856	9.218e-58	214.0	COG0124@1|root,COG0124@2|Bacteria,4PEY8@976|Bacteroidetes,1FJUN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3170778_5	529818.AMSG_05345T0	3.11e-20	107.0	2BFIX@1|root,2S176@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP
CMS3_k127_3170778_4	316274.Haur_4998	1.987e-28	134.0	COG3210@1|root,COG3391@1|root,COG5184@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Beta_helix,CHU_C,Calx-beta,DUF4347,FG-GAP,HYR,VCBS
CMS3_k127_3170778_2	1157490.EL26_04445	1.967e-36	147.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4HK6C@91061|Bacilli,278I8@186823|Alicyclobacillaceae	91061|Bacilli	S	Peptidase family M50	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_3170778_6	871963.Desdi_2165	1.467e-12	77.0	COG2206@1|root,COG2206@2|Bacteria,1VDUC@1239|Firmicutes,25DNP@186801|Clostridia,262JQ@186807|Peptococcaceae	186801|Clostridia	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_3170778_1	926550.CLDAP_02150	6.688e-130	428.0	COG0438@1|root,COG0438@2|Bacteria,2G67A@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3170778_0	926569.ANT_09980	0.0	1722.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS3_k127_3170778_3	608538.HTH_1380	4.094e-33	145.0	COG3210@1|root,COG3227@1|root,COG3210@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.2.1.18,3.4.11.10	ko:K01186,ko:K05994,ko:K21449	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko01002,ko02000,ko02042	1.B.40.2	GH33	-	Beta_helix,PKD,Peptidase_S74,fn3
CMS3_k127_3175785_1	316274.Haur_0047	7.375e-118	394.0	COG3552@1|root,COG3552@2|Bacteria,2G60I@200795|Chloroflexi,3757T@32061|Chloroflexia	32061|Chloroflexia	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_3175785_0	383372.Rcas_0654	4.954e-135	436.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,374WI@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS3_k127_3175785_2	215803.DB30_1803	3.255e-37	149.0	COG3344@1|root,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,42WGB@68525|delta/epsilon subdivisions,2WQ7V@28221|Deltaproteobacteria,2YZ1Y@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1
CMS3_k127_3177430_6	324602.Caur_2141	2.84e-07	62.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2G6C0@200795|Chloroflexi,375ST@32061|Chloroflexia	32061|Chloroflexia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
CMS3_k127_3177430_4	1089553.Tph_c07150	1.638e-46	172.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS3_k127_3177430_3	118161.KB235922_gene2849	2.784e-49	203.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_4,Cadherin,Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,PA14,SNase,SdiA-regulated
CMS3_k127_3177430_0	1137281.D778_00480	1.115e-202	674.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,4PNZU@976|Bacteroidetes,1I0B8@117743|Flavobacteriia	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,HYR,P_proprotein,Peptidase_M36
CMS3_k127_3177430_5	891968.Anamo_1063	4.621e-37	143.0	COG0780@1|root,COG0780@2|Bacteria,3TCFU@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS3_k127_3177430_1	765420.OSCT_3000	4.123e-87	299.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
CMS3_k127_3177430_2	1535422.ND16A_1223	2.297e-61	237.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,1RQ6X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3182759_7	1274374.CBLK010000072_gene1004	2.705e-05	49.0	COG0640@1|root,COG0640@2|Bacteria,1V1HY@1239|Firmicutes,4HG51@91061|Bacilli,26RZX@186822|Paenibacillaceae	91061|Bacilli	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_3182759_0	706587.Desti_0176	3.905e-149	477.0	COG0214@1|root,COG0214@2|Bacteria,1MXHW@1224|Proteobacteria,42MNV@68525|delta/epsilon subdivisions,2WKCJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
CMS3_k127_3182759_3	706587.Desti_0177	7.21e-66	238.0	COG0311@1|root,COG0311@2|Bacteria,1RI7S@1224|Proteobacteria,42SVN@68525|delta/epsilon subdivisions,2WPBZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
CMS3_k127_3182759_1	1147.D082_25660	4.174e-83	314.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
CMS3_k127_3182759_5	41431.PCC8801_3732	2.989e-25	109.0	2CBXQ@1|root,2ZRAK@2|Bacteria,1GIPD@1117|Cyanobacteria,3KK95@43988|Cyanothece	1117|Cyanobacteria	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
CMS3_k127_3182759_4	41431.PCC8801_3731	1.144e-32	129.0	COG2929@1|root,COG2929@2|Bacteria,1GGJG@1117|Cyanobacteria,3KKJ6@43988|Cyanothece	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS3_k127_3182759_2	1304865.JAGF01000001_gene124	1.308e-74	262.0	28I7A@1|root,2Z8A6@2|Bacteria,2IF3R@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3182759_6	554065.XP_005850881.1	1.218e-12	74.0	2CN0D@1|root,2QT3P@2759|Eukaryota,37K58@33090|Viridiplantae,34M0G@3041|Chlorophyta	3041|Chlorophyta	V	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
CMS3_k127_3184371_5	1192034.CAP_0755	2.497e-25	124.0	2DFB4@1|root,2ZR5U@2|Bacteria,1PAWI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3184371_2	1395513.P343_15565	3.793e-92	314.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,4HDPM@91061|Bacilli	91061|Bacilli	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
CMS3_k127_3184371_6	523791.Kkor_1038	9.282e-16	92.0	2DMRH@1|root,32T76@2|Bacteria,1R0QW@1224|Proteobacteria,1SJCG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3184371_1	485913.Krac_10556	2.535e-130	443.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_3184371_4	485913.Krac_6031	1.294e-71	248.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_3184371_0	258533.BN977_03375	3.843e-133	452.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_3184371_3	926554.KI912633_gene3679	5.629e-75	260.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_31981_2	391612.CY0110_00200	2.815e-05	49.0	COG2337@1|root,COG2337@2|Bacteria,1GKIE@1117|Cyanobacteria,3KK5N@43988|Cyanothece	1117|Cyanobacteria	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CMS3_k127_31981_0	926550.CLDAP_32580	1.19e-309	971.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS3_k127_31981_1	1265505.ATUG01000002_gene2404	2.293e-122	397.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria,2MIP6@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF4339
CMS3_k127_3199498_1	521674.Plim_2133	8.563e-06	57.0	2CJB4@1|root,32S9P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3199498_0	926554.KI912680_gene831	1.061e-21	98.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
CMS3_k127_3201460_7	255470.cbdbA1002	6.179e-16	86.0	COG0645@1|root,COG0645@2|Bacteria,2GBGC@200795|Chloroflexi,34CRH@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS3_k127_3201460_4	1120973.AQXL01000115_gene638	1.404e-31	138.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli,279WT@186823|Alicyclobacillaceae	91061|Bacilli	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_3201460_2	404589.Anae109_0052	2.186e-70	248.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS3_k127_3201460_3	926550.CLDAP_15770	5.895e-32	140.0	2EPQX@1|root,33HBF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3201460_5	518766.Rmar_1812	6.147e-25	106.0	COG1254@1|root,COG1254@2|Bacteria,4NVB4@976|Bacteroidetes,1FJMR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS3_k127_3201460_1	867845.KI911784_gene3729	6.612e-96	325.0	COG0167@1|root,COG0167@2|Bacteria,2G8AY@200795|Chloroflexi,3755A@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_3201460_6	710687.KI912270_gene4560	2.074e-17	95.0	28JQV@1|root,2Z7R2@2|Bacteria,2IBX7@201174|Actinobacteria,236QC@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3201460_0	926569.ANT_15910	2.22e-281	874.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS3_k127_3201460_8	1267534.KB906754_gene3082	5.742e-06	55.0	COG0703@1|root,COG0703@2|Bacteria,3Y4R0@57723|Acidobacteria,2JJAZ@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS3_k127_3206958_0	1128421.JAGA01000003_gene3234	1.194e-80	287.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
CMS3_k127_3213835_1	1157638.KB892161_gene3122	4.876e-71	247.0	COG0500@1|root,COG2226@2|Bacteria,2IIA4@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_3213835_0	1125971.ASJB01000053_gene4771	2.101e-86	295.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4DZWC@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
CMS3_k127_3214586_1	1121459.AQXE01000010_gene1927	1.309e-40	155.0	COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,42PYI@68525|delta/epsilon subdivisions,2WVRW@28221|Deltaproteobacteria,2M9EQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_3214586_0	448385.sce5974	5.709e-93	312.0	COG0412@1|root,COG0412@2|Bacteria,1PSEB@1224|Proteobacteria,4340G@68525|delta/epsilon subdivisions,2X4F0@28221|Deltaproteobacteria,2YYWA@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_3216251_2	926550.CLDAP_31620	4.199e-51	184.0	COG0438@1|root,COG0438@2|Bacteria,2G75E@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_3216251_1	706587.Desti_2993	2.97e-54	197.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_3216251_3	1120950.KB892713_gene2470	5.964e-23	104.0	2CFP9@1|root,344WT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3216251_0	926550.CLDAP_31600	4.873e-63	222.0	COG1063@1|root,COG1063@2|Bacteria,2G6FN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
CMS3_k127_321755_3	1540221.JQNI01000002_gene1294	5.079e-15	76.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16,Methyltransf_23,Methyltransf_25
CMS3_k127_321755_1	1173022.Cri9333_0857	1.079e-84	294.0	COG0430@1|root,COG0430@2|Bacteria,1G3A2@1117|Cyanobacteria,1HEVD@1150|Oscillatoriales	1117|Cyanobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
CMS3_k127_321755_0	926569.ANT_05010	5.105e-119	392.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS3_k127_321755_2	1122176.KB903531_gene2817	4.383e-45	175.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1IWBX@117747|Sphingobacteriia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
CMS3_k127_3220143_0	266117.Rxyl_2946	8.266e-65	244.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS3_k127_3220143_1	1541959.KQ51_01493	1.051e-56	207.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_3227152_1	926569.ANT_16010	1.277e-91	310.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS3_k127_3227152_2	525309.HMPREF0494_1819	1.782e-35	142.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS3_k127_3227152_4	555079.Toce_1067	2.545e-16	83.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42H76@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
CMS3_k127_3227152_3	926569.ANT_16040	6.5e-27	114.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS3_k127_3227152_0	926550.CLDAP_37840	2.601e-159	514.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS3_k127_3248872_0	479434.Sthe_2405	1.923e-31	138.0	2CXTU@1|root,32BV2@2|Bacteria,2G9TJ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3248872_1	1192868.CAIU01000028_gene3728	2.163e-23	113.0	2CXTU@1|root,32T2K@2|Bacteria,1N5AY@1224|Proteobacteria,2UDIB@28211|Alphaproteobacteria,43HED@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1176)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1176
CMS3_k127_3248872_2	485913.Krac_6370	2.342e-15	79.0	arCOG13956@1|root,33BWW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3254750_1	485913.Krac_7459	1.2e-41	168.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
CMS3_k127_3254750_0	926560.KE387023_gene3595	2.701e-55	215.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS3_k127_3257568_0	926569.ANT_19420	6.099e-33	142.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
CMS3_k127_3257568_2	1121946.AUAX01000052_gene8144	5.475e-08	61.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_3257568_1	926569.ANT_19460	9.596e-25	107.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS3_k127_3257671_4	56780.SYN_02215	2.114e-15	89.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9
CMS3_k127_3257671_2	1121403.AUCV01000007_gene1213	2.428e-57	216.0	COG4427@1|root,COG4427@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
CMS3_k127_3257671_0	765420.OSCT_0896	2.823e-110	371.0	COG0477@1|root,COG2814@2|Bacteria,2GA8S@200795|Chloroflexi,37818@32061|Chloroflexia	32061|Chloroflexia	EGP	PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
CMS3_k127_3257671_1	479434.Sthe_2042	7.979e-75	263.0	COG0389@1|root,COG0389@2|Bacteria,2G6I6@200795|Chloroflexi,27YX5@189775|Thermomicrobia	189775|Thermomicrobia	L	impB/mucB/samB family	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
CMS3_k127_3257671_3	639282.DEFDS_2016	1.702e-31	132.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS3_k127_3262311_0	311424.DhcVS_932	2.596e-37	161.0	COG4166@1|root,COG4166@2|Bacteria,2G81T@200795|Chloroflexi,34DKF@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_3267795_0	483219.LILAB_24940	5.655e-199	650.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,PP-binding,Thioesterase
CMS3_k127_3267795_1	1173023.KE650771_gene5335	1.354e-191	635.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS3_k127_3267795_2	927677.ALVU02000001_gene2672	5.628e-108	359.0	COG2175@1|root,COG2175@2|Bacteria,1G1VU@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Taurine catabolism dioxygenase TauD TfdA	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS3_k127_3269734_2	926569.ANT_25700	3.624e-117	397.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_3269734_13	926569.ANT_19040	3.924e-11	68.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3269734_0	926550.CLDAP_37280	3.462e-279	876.0	COG0500@1|root,COG2256@1|root,COG0500@2|Bacteria,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS3_k127_3269734_5	309801.trd_0433	1.245e-71	250.0	COG0689@1|root,COG0689@2|Bacteria,2G69E@200795|Chloroflexi,27Y55@189775|Thermomicrobia	189775|Thermomicrobia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS3_k127_3269734_1	926569.ANT_18180	3.517e-119	398.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_3269734_3	926550.CLDAP_12760	7.382e-87	297.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
CMS3_k127_3269734_11	391937.NA2_00900	1.175e-15	85.0	COG1920@1|root,COG1920@2|Bacteria,1RJPN@1224|Proteobacteria,2UAA7@28211|Alphaproteobacteria,43PJS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
CMS3_k127_3269734_4	926569.ANT_17680	9.983e-86	293.0	COG2047@1|root,COG2047@2|Bacteria	2|Bacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
CMS3_k127_3269734_6	1382359.JIAL01000001_gene1878	5.926e-62	228.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	yqhO	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_3269734_7	316274.Haur_4404	6.154e-57	216.0	COG0642@1|root,COG2205@2|Bacteria,2G84W@200795|Chloroflexi,3775F@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_3269734_9	316274.Haur_1271	4.403e-22	100.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HATPase_c,Response_reg
CMS3_k127_3269734_8	861299.J421_4182	1.591e-29	128.0	COG1853@1|root,COG1853@2|Bacteria,1ZTVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_3269734_10	926550.CLDAP_34250	3.122e-21	96.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
CMS3_k127_3292911_1	485913.Krac_2150	1.559e-39	152.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	2|Bacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_3292911_2	926550.CLDAP_05910	1.234e-32	128.0	COG1522@1|root,COG1522@2|Bacteria,2G99D@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
CMS3_k127_3292911_3	1122176.KB903541_gene262	2.284e-18	88.0	COG0296@1|root,COG3743@1|root,COG0296@2|Bacteria,COG3743@2|Bacteria,4NUCY@976|Bacteroidetes,1IYR1@117747|Sphingobacteriia	976|Bacteroidetes	G	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,DUF4332
CMS3_k127_3292911_0	649638.Trad_1962	2.303e-132	429.0	COG4989@1|root,COG4989@2|Bacteria,1WMFY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_329550_0	316274.Haur_4201	5.005e-79	267.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi,375JG@32061|Chloroflexia	32061|Chloroflexia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_329550_1	926550.CLDAP_34200	5.09e-23	100.0	2E5PY@1|root,330EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3310664_2	1184609.KILIM_049_00120	7.039e-58	205.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4F61I@85018|Dermatophilaceae	201174|Actinobacteria	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
CMS3_k127_3310664_3	926550.CLDAP_19750	5.166e-25	108.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
CMS3_k127_3310664_0	926550.CLDAP_32690	1.01e-295	921.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2G7SW@200795|Chloroflexi	200795|Chloroflexi	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS3_k127_3310664_1	926550.CLDAP_32700	2.221e-112	366.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
CMS3_k127_3316692_0	886293.Sinac_7054	3.068e-154	520.0	COG0318@1|root,COG1020@1|root,COG1028@1|root,COG3321@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2IXBN@203682|Planctomycetes	203682|Planctomycetes	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
CMS3_k127_3325940_0	203124.Tery_4973	7.788e-29	136.0	COG0265@1|root,COG0265@2|Bacteria,1GQZK@1117|Cyanobacteria,1HI61@1150|Oscillatoriales	1117|Cyanobacteria	O	GUN4-like	-	-	-	-	-	-	-	-	-	-	-	-	GUN4
CMS3_k127_3325940_1	1499967.BAYZ01000054_gene4795	4.26e-28	116.0	2E91Y@1|root,333B3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3334303_0	765420.OSCT_0887	7.15e-83	297.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
CMS3_k127_3334303_1	1173025.GEI7407_0523	3.052e-42	162.0	COG0500@1|root,COG0500@2|Bacteria,1G56P@1117|Cyanobacteria,1HAXF@1150|Oscillatoriales	1117|Cyanobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
CMS3_k127_3338448_1	357808.RoseRS_1819	3.931e-101	352.0	COG0616@1|root,COG0616@2|Bacteria,2G7XF@200795|Chloroflexi	200795|Chloroflexi	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_3338448_2	926569.ANT_07770	1.959e-100	334.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
CMS3_k127_3338448_0	335543.Sfum_2279	1.046e-154	509.0	COG1404@1|root,COG1404@2|Bacteria,1PFBD@1224|Proteobacteria,43A1G@68525|delta/epsilon subdivisions,2X9U2@28221|Deltaproteobacteria,2MSGE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_3338448_3	926569.ANT_03630	1.24e-88	302.0	COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
CMS3_k127_3338448_4	926569.ANT_03640	2.346e-35	141.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_333861_3	287.DR97_2941	1.169e-22	108.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1YDHQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_333861_1	1157490.EL26_17490	5.574e-115	388.0	COG0667@1|root,COG0667@2|Bacteria,1V53W@1239|Firmicutes,4HTG5@91061|Bacilli	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_333861_0	82996.sch_06990	3.121e-125	416.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,401PR@613|Serratia	1236|Gammaproteobacteria	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	iYL1228.KPN_02462	AdoHcyase,AdoHcyase_NAD
CMS3_k127_333861_2	926550.CLDAP_29890	4.473e-43	161.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
CMS3_k127_3340984_0	1121377.KB906404_gene2877	2.092e-117	429.0	COG0515@1|root,COG0515@2|Bacteria,1WIDK@1297|Deinococcus-Thermus	1121377.KB906404_gene2877|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3340984_3	1121377.KB906404_gene2878	6.29e-36	160.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS3_k127_3340984_1	889378.Spiaf_2257	3.645e-67	241.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
CMS3_k127_3340984_2	1480694.DC28_03655	1.927e-52	198.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	MA20_22965	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_3340984_6	313612.L8106_26852	1.119e-13	80.0	COG1357@1|root,COG1357@2|Bacteria,1G2PD@1117|Cyanobacteria,1H9MS@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_3340984_5	1041930.Mtc_1580	1.05e-19	102.0	COG0477@1|root,arCOG00132@2157|Archaea,2XYHV@28890|Euryarchaeota,2NAK2@224756|Methanomicrobia	224756|Methanomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_3364377_2	926550.CLDAP_27060	6.805e-73	281.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20,fn3
CMS3_k127_3364377_0	324602.Caur_1313	0.0	1245.0	COG1523@1|root,COG1523@2|Bacteria,2G7WM@200795|Chloroflexi,376JG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_48,DUF3372
CMS3_k127_3364377_1	1123508.JH636450_gene7219	1.714e-173	587.0	COG1404@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG4935@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,2IZWN@203682|Planctomycetes	203682|Planctomycetes	Q	HemY domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3389509_1	1193181.BN10_1130002	2.245e-08	57.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4FFB8@85021|Intrasporangiaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_3389509_2	1192034.CAP_6765	7.086e-07	54.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	-	ko:K21781	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002	-	-	-	PP-binding
CMS3_k127_3389509_0	388467.A19Y_3284	9.679e-69	250.0	28KEP@1|root,2ZA0W@2|Bacteria,1G2EV@1117|Cyanobacteria,1H8V1@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3395006_1	926550.CLDAP_01280	6.919e-78	274.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3395006_4	1096930.L284_22060	1.77e-27	121.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria,2KCQ1@204457|Sphingomonadales	204457|Sphingomonadales	K	Regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_3395006_3	449447.MAE_16340	1.258e-38	145.0	COG3549@1|root,COG3549@2|Bacteria,1G77Y@1117|Cyanobacteria	1117|Cyanobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CMS3_k127_3395006_2	1229172.JQFA01000002_gene2434	4.994e-43	159.0	COG3093@1|root,COG3093@2|Bacteria,1G82A@1117|Cyanobacteria,1HCXA@1150|Oscillatoriales	1117|Cyanobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CMS3_k127_3395006_0	316274.Haur_2040	1.552e-113	391.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2G71Q@200795|Chloroflexi,376GZ@32061|Chloroflexia	2|Bacteria	NU	SMART Tetratricopeptide domain protein	-	-	2.7.11.1,3.6.4.12	ko:K03654,ko:K11935,ko:K14949,ko:K21007	ko02025,ko02026,ko03018,ko05152,map02025,map02026,map03018,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03400	-	-	-	Pkinase,PknG_TPR,PknG_rubred,TPR_15,TPR_16,TPR_19
CMS3_k127_3400027_0	926550.CLDAP_34260	2.152e-88	306.0	COG0477@1|root,COG2814@2|Bacteria,2G96S@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_3401339_0	880073.Calab_2608	7.982e-69	259.0	COG4191@1|root,COG4191@2|Bacteria	880073.Calab_2608|-	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3401339_2	649638.Trad_1394	8.906e-20	91.0	COG3905@1|root,COG3905@2|Bacteria	2|Bacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	vapB43	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	RHH_1
CMS3_k127_3401339_1	870187.Thini_1711	5.329e-56	198.0	COG1848@1|root,COG1848@2|Bacteria,1N8VX@1224|Proteobacteria,1SP0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS3_k127_3401339_3	1120934.KB894403_gene314	0.0006945	49.0	COG1361@1|root,COG3266@1|root,COG4655@1|root,COG1361@2|Bacteria,COG3266@2|Bacteria,COG4655@2|Bacteria	2|Bacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	2.7.11.1	ko:K11904,ko:K12132	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02044	3.A.23.1	-	-	CHU_C,DUF11,Gram_pos_anchor,He_PIG,Tad
CMS3_k127_3405040_4	373903.Hore_21550	3.929e-84	282.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3WA6K@53433|Halanaerobiales	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS3_k127_3405040_3	335543.Sfum_0702	8.947e-95	316.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42NXP@68525|delta/epsilon subdivisions,2WK2A@28221|Deltaproteobacteria,2MRC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_3405040_0	335543.Sfum_0703	5.276e-110	365.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS3_k127_3405040_1	335543.Sfum_0704	3.118e-109	362.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MQY5@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS3_k127_3405040_2	926569.ANT_02630	5.317e-106	355.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_3405040_5	316274.Haur_4010	1.05e-22	104.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
CMS3_k127_3406647_0	1265505.ATUG01000002_gene1883	5.001e-115	382.0	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,42PFS@68525|delta/epsilon subdivisions,2WIR3@28221|Deltaproteobacteria,2MI8U@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
CMS3_k127_3406647_1	326427.Cagg_0426	1.211e-37	150.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi,375VW@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Thiamin pyrophosphokinase, catalytic region	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
CMS3_k127_3409434_3	525904.Tter_2673	1.336e-37	147.0	COG3279@1|root,COG3839@1|root,COG3279@2|Bacteria,COG3839@2|Bacteria	2|Bacteria	P	tungstate ion transport	-	-	-	ko:K01990,ko:K07705,ko:K10112	ko02010,ko02020,map02010,map02020	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00254,M00491,M00492,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1,3.A.1.1	-	-	ABC_tran,LytTR,Response_reg
CMS3_k127_3409434_1	479434.Sthe_2097	1.085e-79	272.0	COG1131@1|root,COG1131@2|Bacteria,2G6HN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3409434_10	485913.Krac_8571	6.296e-05	55.0	COG1668@1|root,COG1668@2|Bacteria,2GA92@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_3409434_4	926550.CLDAP_22280	4.446e-30	122.0	COG3019@1|root,COG3019@2|Bacteria	2|Bacteria	S	metal-binding protein	copG	-	-	-	-	-	-	-	-	-	-	-	DUF411
CMS3_k127_3409434_2	1121033.AUCF01000026_gene2970	3.148e-53	196.0	COG0664@1|root,COG0664@2|Bacteria,1NPY0@1224|Proteobacteria,2TT13@28211|Alphaproteobacteria,2JS8J@204441|Rhodospirillales	204441|Rhodospirillales	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_3409434_9	349102.Rsph17025_0969	1.998e-09	65.0	2EKB5@1|root,3351G@2|Bacteria,1QYR7@1224|Proteobacteria,2TXX7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3409434_7	765420.OSCT_1575	7.177e-15	83.0	COG2333@1|root,COG4223@1|root,COG2333@2|Bacteria,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	DUF1631,Lactamase_B,PE-PPE
CMS3_k127_3409434_8	1894.JOER01000051_gene5397	1.383e-11	77.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS3_k127_3409434_0	1227739.Hsw_1068	2.571e-142	467.0	COG0161@1|root,COG0161@2|Bacteria,4PMIJ@976|Bacteroidetes,47Q50@768503|Cytophagia	976|Bacteroidetes	H	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
CMS3_k127_3409434_5	387092.NIS_0278	2.561e-28	116.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,43B6G@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_3409434_6	1125863.JAFN01000001_gene3134	1.259e-24	110.0	COG2050@1|root,COG3303@1|root,COG2050@2|Bacteria,COG3303@2|Bacteria,1R0AE@1224|Proteobacteria,43CSS@68525|delta/epsilon subdivisions,2WU2I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_3414918_4	926550.CLDAP_06250	6.824e-14	75.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1
CMS3_k127_3414918_0	926550.CLDAP_06250	1.645e-68	246.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1
CMS3_k127_3414918_2	208444.JNYY01000001_gene4757	1.951e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,2IKG3@201174|Actinobacteria,4EEZ7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3414918_3	1121933.AUHH01000021_gene1645	8.425e-30	123.0	COG5485@1|root,COG5485@2|Bacteria,2IMH5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_3414918_1	42256.RradSPS_0358	3.314e-38	151.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_3414952_1	926550.CLDAP_02120	6.761e-51	201.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44,Glyco_hydro_cc,Laminin_G_3,PA14
CMS3_k127_3414952_0	298386.PBPRB0050	2.813e-117	392.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XWFX@135623|Vibrionales	135623|Vibrionales	C	cytochrome c peroxidase	yhjA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd
CMS3_k127_342030_1	383372.Rcas_2810	4.957e-90	314.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1,3.2.1.50	ko:K01205,ko:K07004,ko:K12132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko04147	-	-	-	DUF3662,DUF916,FHA,NAGLU,NAGLU_C,NAGLU_N,Yop-YscD_cpl
CMS3_k127_342030_0	1173264.KI913949_gene1329	1.169e-131	428.0	COG2008@1|root,COG2008@2|Bacteria,1G4PN@1117|Cyanobacteria	1117|Cyanobacteria	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_3423245_0	316274.Haur_1430	2.405e-93	333.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_3432658_1	1173025.GEI7407_1493	1.159e-116	385.0	COG1916@1|root,COG1916@2|Bacteria,1G4FN@1117|Cyanobacteria,1H89R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3432658_2	378806.STAUR_3205	1.02e-57	206.0	COG1916@1|root,COG1916@2|Bacteria,1Q79N@1224|Proteobacteria,439FM@68525|delta/epsilon subdivisions,2X4R8@28221|Deltaproteobacteria,2YZFG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3432658_0	102129.Lepto7375DRAFT_5777	1.887e-170	546.0	COG0714@1|root,COG0714@2|Bacteria,1G37K@1117|Cyanobacteria,1H9VV@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS3_k127_3432658_3	1173025.GEI7407_1495	1.653e-07	61.0	COG5094@1|root,COG5094@2|Bacteria,1G59D@1117|Cyanobacteria,1HANY@1150|Oscillatoriales	1117|Cyanobacteria	K	RNA polymerase II transcriptional preinitiation complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3433213_1	926569.ANT_09720	9.997e-156	517.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS3_k127_3433213_10	479434.Sthe_2014	4.473e-07	61.0	COG2891@1|root,COG2891@2|Bacteria,2GBC9@200795|Chloroflexi,27YRC@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	MreD
CMS3_k127_3433213_6	926550.CLDAP_08160	2.17e-42	166.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS3_k127_3433213_0	926569.ANT_09690	1.8e-159	509.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_3433213_7	926569.ANT_30300	3.777e-32	131.0	2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3433213_2	671143.DAMO_2078	3.987e-78	274.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_3433213_3	395961.Cyan7425_0352	1.272e-76	263.0	COG1028@1|root,COG1028@2|Bacteria,1G4JP@1117|Cyanobacteria,3KH1N@43988|Cyanothece	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3433213_9	479434.Sthe_3270	2.024e-19	100.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3433213_5	1123400.KB904791_gene136	1.431e-46	169.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS3_k127_3433213_4	1128421.JAGA01000002_gene1498	3.762e-64	235.0	COG1502@1|root,COG1502@2|Bacteria,2NQ5Z@2323|unclassified Bacteria	2|Bacteria	I	PLD-like domain	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS3_k127_3433999_1	1082931.KKY_3665	1.489e-30	130.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,3N7JX@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033,ko:K13890	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1
CMS3_k127_3433999_0	644966.Tmar_1945	1.972e-38	167.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WCG5@538999|Clostridiales incertae sedis	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_3433999_2	1229276.DI53_0844	1.112e-11	79.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1IQ2M@117747|Sphingobacteriia	976|Bacteroidetes	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_3441052_3	479434.Sthe_0586	3.998e-32	143.0	COG3266@1|root,COG3266@2|Bacteria,2GBHM@200795|Chloroflexi,27Y68@189775|Thermomicrobia	189775|Thermomicrobia	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_3441052_0	357808.RoseRS_2625	2.647e-92	308.0	COG0745@1|root,COG0745@2|Bacteria,2G7U0@200795|Chloroflexi	200795|Chloroflexi	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3441052_2	357808.RoseRS_2626	2.795e-71	258.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi,375B4@32061|Chloroflexia	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_3441052_1	457425.XNR_2371	1.324e-80	278.0	COG1131@1|root,COG1131@2|Bacteria,2GNQJ@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_3441052_4	1333523.L593_08530	1.644e-08	55.0	COG3358@1|root,arCOG04570@2157|Archaea,2XWQ3@28890|Euryarchaeota,23V6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CMS3_k127_344583_1	485913.Krac_5920	3.237e-91	306.0	COG0641@1|root,COG0641@2|Bacteria,2G74V@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SPASM
CMS3_k127_344583_2	373994.Riv7116_2795	3.332e-68	256.0	COG0823@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2931@2|Bacteria,1GQ7W@1117|Cyanobacteria,1HTNJ@1161|Nostocales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4114)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,FG-GAP
CMS3_k127_344583_6	1215092.PA6_008_00210	1.457e-17	98.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
CMS3_k127_344583_0	316274.Haur_2040	1.695e-109	391.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2G71Q@200795|Chloroflexi,376GZ@32061|Chloroflexia	2|Bacteria	NU	SMART Tetratricopeptide domain protein	-	-	2.7.11.1,3.6.4.12	ko:K03654,ko:K11935,ko:K14949,ko:K21007	ko02025,ko02026,ko03018,ko05152,map02025,map02026,map03018,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03400	-	-	-	Pkinase,PknG_TPR,PknG_rubred,TPR_15,TPR_16,TPR_19
CMS3_k127_344583_5	1297742.A176_01465	2.813e-22	112.0	COG2755@1|root,COG5640@1|root,COG2755@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,Lipase_GDSL_2,Trypsin
CMS3_k127_344583_4	1121035.AUCH01000004_gene310	1.886e-40	171.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
CMS3_k127_344583_3	1121380.JNIW01000017_gene2949	1.182e-62	239.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
CMS3_k127_347408_0	796942.HMPREF9623_00100	7.796e-49	182.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS3_k127_347408_2	1415780.JPOG01000001_gene1996	6.112e-29	120.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SZKQ@1236|Gammaproteobacteria,1XCWA@135614|Xanthomonadales	135614|Xanthomonadales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_347408_3	1148.1001482	3.168e-12	79.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H6CY@1142|Synechocystis	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS3_k127_3476592_15	926569.ANT_20630	4.806e-20	102.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS3_k127_3476592_14	926569.ANT_20630	3.063e-24	116.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS3_k127_3476592_4	485913.Krac_11738	1.146e-78	270.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_3476592_10	479434.Sthe_1384	1.017e-55	202.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,27YBV@189775|Thermomicrobia	189775|Thermomicrobia	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS3_k127_3476592_16	1461580.CCAS010000015_gene1842	1.309e-07	57.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3476592_0	485913.Krac_2238	1.744e-115	401.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,2G7JR@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
CMS3_k127_3476592_3	485913.Krac_2239	5.922e-80	272.0	COG0745@1|root,COG0745@2|Bacteria,2G81R@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3476592_2	1089552.KI911559_gene2276	1.407e-91	317.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2VFEC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS3_k127_3476592_7	666684.AfiDRAFT_1899	1.356e-60	220.0	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,2TT3V@28211|Alphaproteobacteria,3JUY0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_3476592_9	1125863.JAFN01000001_gene1330	4.015e-57	212.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,43AW2@68525|delta/epsilon subdivisions,2X6A9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_3476592_6	402881.Plav_1975	1.824e-64	229.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,1JPXP@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_3476592_5	381666.H16_B2012	1.848e-71	251.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VNUS@28216|Betaproteobacteria,1KGDT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_3476592_11	525897.Dbac_0707	6.641e-39	149.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42R80@68525|delta/epsilon subdivisions,2WMW6@28221|Deltaproteobacteria,2MARF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_3476592_8	1121106.JQKB01000005_gene2136	3.433e-58	218.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TRA4@28211|Alphaproteobacteria,2JQSE@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_3476592_13	926550.CLDAP_13510	2.064e-25	109.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_3476592_12	926550.CLDAP_13520	6.938e-28	115.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_3476592_1	926550.CLDAP_00330	4.543e-95	314.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS3_k127_3479773_4	478741.JAFS01000002_gene615	3.344e-51	187.0	2E0P7@1|root,32UPH@2|Bacteria,46YDQ@74201|Verrucomicrobia,37GK1@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	Protoglobin
CMS3_k127_3479773_0	1313172.YM304_14090	1.723e-113	378.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	thiY	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS3_k127_3479773_3	526227.Mesil_2099	6.729e-52	194.0	COG0600@1|root,COG0600@2|Bacteria,1WM4A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS3_k127_3479773_1	526227.Mesil_2104	6.984e-96	321.0	COG1116@1|root,COG1116@2|Bacteria,1WM71@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS3_k127_3479773_2	1463855.JOHV01000020_gene3024	5.509e-60	224.0	COG0600@1|root,COG0600@2|Bacteria,2HDX7@201174|Actinobacteria	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS3_k127_3479773_5	765420.OSCT_1117	7.749e-37	152.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_3493644_0	316274.Haur_3626	6.817e-233	734.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_3493644_1	316274.Haur_3627	4.192e-68	237.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,37630@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_3499175_1	608538.HTH_0156	1.245e-52	202.0	COG1148@1|root,COG1290@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	napF	-	-	ko:K02572,ko:K02573,ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	CCG,Cytochrome_B,FAD_binding_6,Fer2,Fer4,Fer4_4,Fer4_5,Fer4_7,FlpD,NAD_binding_1
CMS3_k127_3499175_5	316274.Haur_3763	4.665e-18	89.0	COG3474@1|root,COG3474@2|Bacteria,2GA7P@200795|Chloroflexi,3760W@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS3_k127_3499175_0	926550.CLDAP_28410	1.628e-201	650.0	COG0843@1|root,COG0843@2|Bacteria,2G628@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS3_k127_3499175_3	1223521.BBJX01000002_gene2861	2.74e-39	159.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VM89@28216|Betaproteobacteria,4AHA1@80864|Comamonadaceae	28216|Betaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS3_k127_3499175_2	479434.Sthe_2052	2.787e-45	170.0	COG1622@1|root,COG1622@2|Bacteria,2G8QU@200795|Chloroflexi,27YGH@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
CMS3_k127_3499175_4	926569.ANT_08680	5.796e-24	107.0	COG2847@1|root,COG2847@2|Bacteria,2G757@200795|Chloroflexi	200795|Chloroflexi	P	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
CMS3_k127_3499720_1	1128421.JAGA01000004_gene2521	5.138e-94	320.0	COG0006@1|root,COG0006@2|Bacteria,2NP41@2323|unclassified Bacteria	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271,ko:K08326	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_3499720_0	926569.ANT_05200	6.426e-101	336.0	COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi	200795|Chloroflexi	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3499720_2	1128421.JAGA01000003_gene2920	1.046e-49	183.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_3512380_1	1502851.FG93_02368	1.209e-34	149.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria,1MX0Y@1224|Proteobacteria,2TRAZ@28211|Alphaproteobacteria,3K5YR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS3_k127_3512380_2	1219065.VPR01S_27_00290	3.515e-33	143.0	COG0454@1|root,COG0456@2|Bacteria,1RKY5@1224|Proteobacteria,1S445@1236|Gammaproteobacteria,1XXXQ@135623|Vibrionales	135623|Vibrionales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_3512380_0	1242864.D187_006134	6.019e-124	413.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1R0NC@1224|Proteobacteria,43CZ0@68525|delta/epsilon subdivisions,2X877@28221|Deltaproteobacteria,2Z2EZ@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS3_k127_3512507_1	314285.KT71_18426	8.114e-68	234.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
CMS3_k127_3512507_0	864051.BurJ1DRAFT_2685	2.315e-146	483.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS3_k127_351579_1	316274.Haur_2970	4.408e-29	130.0	COG3502@1|root,COG3502@2|Bacteria,2G9SI@200795|Chloroflexi,3760N@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
CMS3_k127_351579_0	1540257.JQMW01000012_gene2642	7.304e-70	250.0	COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,2482S@186801|Clostridia,36GH9@31979|Clostridiaceae	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
CMS3_k127_351579_2	1537994.JQFW01000003_gene3314	4.089e-12	73.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,467DT@72275|Alteromonadaceae	1236|Gammaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
CMS3_k127_3518816_1	266117.Rxyl_2063	1.24e-198	628.0	COG2224@1|root,COG2224@2|Bacteria,2GNAY@201174|Actinobacteria	201174|Actinobacteria	C	Isocitrate lyase	aceA	GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0006950,GO:0008150,GO:0008152,GO:0009268,GO:0009405,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0010033,GO:0010034,GO:0010447,GO:0016020,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019899,GO:0032787,GO:0033554,GO:0033993,GO:0035375,GO:0036293,GO:0036294,GO:0042221,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046421,GO:0046487,GO:0046677,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0070542,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072350,GO:0075136,GO:0075141,GO:1901700	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
CMS3_k127_3518816_0	414684.RC1_2688	3.97e-215	680.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria	1224|Proteobacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	aceB	GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010	Malate_synthase
CMS3_k127_3518816_2	316274.Haur_1013	4.982e-155	501.0	COG1426@1|root,COG3800@1|root,COG1426@2|Bacteria,COG3800@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	hipB	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_19,HTH_25,HTH_3,HTH_31,Peptidase_M78
CMS3_k127_351918_0	1121324.CLIT_8c01210	3.691e-180	585.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS3_k127_351918_1	1128421.JAGA01000003_gene3156	1.77e-99	333.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3521711_4	326424.FRAAL1668	0.0004358	48.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.3,6.4.1.4	ko:K01965,ko:K01968	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_3521711_1	926569.ANT_25980	1.193e-88	310.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
CMS3_k127_3521711_2	357808.RoseRS_0520	7.575e-57	214.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2GAA9@200795|Chloroflexi,376WV@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
CMS3_k127_3521711_0	1173028.ANKO01000042_gene858	8.287e-203	660.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS3_k127_3534171_6	926550.CLDAP_22240	5.93e-32	134.0	COG1215@1|root,COG1215@2|Bacteria,2G952@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,T2SSE_N
CMS3_k127_3534171_1	243164.DET0911	1.782e-125	411.0	COG2309@1|root,COG2309@2|Bacteria,2G5TH@200795|Chloroflexi,34CT4@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_3534171_7	1304284.L21TH_1929	7.962e-30	122.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,36JSB@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
CMS3_k127_3534171_8	926569.ANT_06730	3.377e-24	107.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3534171_11	1128421.JAGA01000002_gene645	3.348e-11	75.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_3534171_9	926569.ANT_04150	1.249e-15	88.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_3534171_5	926569.ANT_06730	7.284e-34	134.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3534171_3	550540.Fbal_3367	1.46e-50	184.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0019842,GO:0031406,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051870,GO:0051871,GO:0055114,GO:0070401,GO:0070402,GO:0072341,GO:0097159,GO:1901265,GO:1901363	1.5.1.3	ko:K00287,ko:K18590	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	iECBD_1354.ECBD_3567,iECDH1ME8569_1439.ECDH1ME8569_0047,iECNA114_1301.ECNA114_0036,iEcDH1_1363.EcDH1_3551,iEcSMS35_1347.EcSMS35_0050,iG2583_1286.G2583_0050,iJN746.PP_5132,iNRG857_1313.NRG857_00250,iUMN146_1321.UM146_23020	DHFR_1
CMS3_k127_3534171_0	1492922.GY26_13850	4.429e-137	440.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,1J4ZS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422	Thymidylat_synt
CMS3_k127_3534171_10	648885.KB316282_gene1293	8.144e-12	71.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2TXMN@28211|Alphaproteobacteria,1JQWM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
CMS3_k127_3534171_4	926569.ANT_27880	4.575e-40	153.0	COG2166@1|root,COG2166@2|Bacteria,2G6V9@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Fe-S metabolism associated SufE	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
CMS3_k127_3534171_2	316274.Haur_3817	2.918e-58	213.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_3534171_12	1121091.AUMP01000004_gene2278	4.044e-10	68.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH,EcKinase,HMG-CoA_red
CMS3_k127_3538694_1	313628.LNTAR_24319	7.9e-18	87.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	mscS	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS3_k127_3538694_0	661478.OP10G_2436	4.532e-165	530.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3538694_2	243090.RB10666	0.0007808	53.0	COG1361@1|root,COG1361@2|Bacteria,2IYS8@203682|Planctomycetes	203682|Planctomycetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_354289_3	926560.KE387023_gene3098	4.816e-10	73.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,1WMEQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KLT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
CMS3_k127_354289_1	797302.Halru_2755	1.307e-18	101.0	arCOG07561@1|root,arCOG07561@2157|Archaea,2XV3J@28890|Euryarchaeota,23UWG@183963|Halobacteria	183963|Halobacteria	K	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_354289_0	357808.RoseRS_1669	3.228e-88	306.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
CMS3_k127_354289_5	102129.Lepto7375DRAFT_8010	1.393e-08	68.0	COG1470@1|root,COG1470@2|Bacteria,1G0CA@1117|Cyanobacteria,1H8AA@1150|Oscillatoriales	1117|Cyanobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_354289_2	945713.IALB_1599	2.648e-15	91.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
CMS3_k127_354289_4	525909.Afer_0092	1.273e-09	65.0	COG1716@1|root,COG1716@2|Bacteria,2HG8X@201174|Actinobacteria,4CN6T@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
CMS3_k127_3542896_3	1379270.AUXF01000001_gene2437	4.659e-69	268.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
CMS3_k127_3542896_5	246195.DNO_0452	1.999e-65	256.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	ABC transporter substrate-binding protein	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_3542896_4	89187.ISM_12260	1.132e-68	254.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_3542896_6	89187.ISM_12255	2.574e-57	220.0	COG0426@1|root,COG0426@2|Bacteria	2|Bacteria	C	nitric oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_3542896_7	743719.PaelaDRAFT_4443	5.272e-32	128.0	COG2146@1|root,COG2146@2|Bacteria,1V904@1239|Firmicutes,4HI5W@91061|Bacilli,26Z4D@186822|Paenibacillaceae	91061|Bacilli	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_3542896_1	1395571.TMS3_0103285	1.489e-173	550.0	COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria	1224|Proteobacteria	P	metal-dependent hydrolase of the TIM-barrel fold	barH	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_3542896_2	1380391.JIAS01000014_gene2288	2.159e-83	286.0	COG2084@1|root,COG2084@2|Bacteria,1PU4S@1224|Proteobacteria,2TT0X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS3_k127_3542896_0	984262.SGRA_4042	2.195e-191	644.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia	976|Bacteroidetes	S	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
CMS3_k127_3542896_8	926550.CLDAP_30900	4.259e-11	73.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3543401_4	926569.ANT_22580	8.067e-09	68.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
CMS3_k127_3543401_3	330214.NIDE4175	5.456e-48	188.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_3543401_1	926569.ANT_04560	1.926e-71	251.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CMS3_k127_3543401_0	357808.RoseRS_1973	1.496e-118	388.0	COG0208@1|root,COG0208@2|Bacteria,2G610@200795|Chloroflexi,3761D@32061|Chloroflexia	32061|Chloroflexia	F	PFAM ribonucleotide reductase	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS3_k127_3543401_2	926569.ANT_04550	2.847e-62	222.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS3_k127_3554315_0	1033732.CAHI01000030_gene1287	8.275e-83	293.0	COG3408@1|root,COG3408@2|Bacteria,4NI03@976|Bacteroidetes,2FQYR@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
CMS3_k127_3563671_1	383372.Rcas_4066	1.305e-23	116.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3563671_0	69014.TK1719	6.307e-29	130.0	COG2244@1|root,arCOG02209@2157|Archaea,2XZJ5@28890|Euryarchaeota,243YW@183968|Thermococci	183968|Thermococci	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
CMS3_k127_3577801_0	383372.Rcas_1750	2.519e-84	294.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi,3768V@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3577801_1	926569.ANT_25840	2.617e-83	286.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS3_k127_358608_3	1123355.JHYO01000003_gene2881	6.455e-12	67.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,2UJXH@28211|Alphaproteobacteria,37108@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_358608_5	330214.NIDE1616	0.0003307	53.0	2DM57@1|root,31S0Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_358608_1	926569.ANT_07010	1.078e-49	181.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
CMS3_k127_358608_4	1484460.JSWG01000009_gene648	1.991e-06	59.0	2AHBJ@1|root,317N1@2|Bacteria,4P8TZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_358608_0	386415.NT01CX_1554	5.08e-162	522.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,36DV2@31979|Clostridiaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_358608_2	448385.sce1860	7.654e-39	153.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X2ZS@28221|Deltaproteobacteria,2YTUV@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_3593899_5	247634.GPB2148_2282	0.0004057	51.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_3593899_4	639030.JHVA01000001_gene3050	7.132e-13	74.0	COG1879@1|root,COG1879@2|Bacteria,3Y3RJ@57723|Acidobacteria,2JK89@204432|Acidobacteriia	2|Bacteria	K	IclR helix-turn-helix domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	HTH_IclR,LacI,Peripla_BP_4
CMS3_k127_3593899_1	1134474.O59_002438	4.699e-96	324.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,1RNTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
CMS3_k127_3593899_0	1429046.RR21198_2135	2.534e-155	501.0	COG0477@1|root,COG2814@2|Bacteria,2GNBV@201174|Actinobacteria,4FWA7@85025|Nocardiaceae	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_3593899_3	1117318.PRUB_15905	3.465e-23	115.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,2PZKF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_3593899_2	1265505.ATUG01000002_gene1060	1.487e-69	256.0	COG0834@1|root,COG5000@1|root,COG0834@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_3598628_3	161528.ED21_24526	1.871e-22	106.0	COG1266@1|root,COG1266@2|Bacteria,1MYYZ@1224|Proteobacteria,2UBB3@28211|Alphaproteobacteria,2KA9P@204457|Sphingomonadales	204457|Sphingomonadales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_3598628_6	324602.Caur_3333	1.347e-06	53.0	2A4K7@1|root,30T6V@2|Bacteria,2GB43@200795|Chloroflexi,377VP@32061|Chloroflexia	32061|Chloroflexia	S	Ribosomally synthesized peptide prototyped by Frankia Franean1_4349.	-	-	-	-	-	-	-	-	-	-	-	-	Frankia_peptide
CMS3_k127_3598628_2	1254432.SCE1572_22155	1.256e-24	111.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_3598628_1	1210884.HG799465_gene11440	1.314e-29	123.0	28WG9@1|root,2ZIGE@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_3598628_5	1121935.AQXX01000127_gene1130	8.623e-07	56.0	COG4319@1|root,COG4319@2|Bacteria,1N8AM@1224|Proteobacteria	1224|Proteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS3_k127_3598628_0	89187.ISM_00740	9.684e-64	234.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_3598628_4	224308.BSU35190	3.939e-09	58.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HDHF@91061|Bacilli,1ZQ5X@1386|Bacillus	91061|Bacilli	GT	Phosphotransferase	yvkC	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS3_k127_3600161_6	479432.Sros_6579	3.579e-11	66.0	COG4585@1|root,COG4585@2|Bacteria,2IBWF@201174|Actinobacteria,4EQQS@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_3600161_0	485913.Krac_6031	5.1e-74	255.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_3600161_1	1183438.GKIL_3503	7.635e-40	153.0	2DTCT@1|root,33JRA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3600161_4	926569.ANT_08270	1.801e-30	136.0	COG0477@1|root,COG2814@2|Bacteria,2G6XW@200795|Chloroflexi	200795|Chloroflexi	EGP	Nucleoside H+ symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
CMS3_k127_3600161_3	875328.JDM601_2074	1.125e-32	141.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,236F7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
CMS3_k127_3600161_2	671143.DAMO_2439	1.355e-33	139.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_3600161_5	66875.JODY01000062_gene25	5.354e-22	104.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_3600988_2	1121377.KB906404_gene2877	1.478e-54	200.0	COG0515@1|root,COG0515@2|Bacteria,1WIDK@1297|Deinococcus-Thermus	1121377.KB906404_gene2877|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3600988_0	754476.Q7A_97	2.53e-134	436.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,460G0@72273|Thiotrichales	72273|Thiotrichales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS3_k127_3600988_3	485916.Dtox_2413	6.902e-07	59.0	COG3012@1|root,COG3012@2|Bacteria,1V0U4@1239|Firmicutes,24FCY@186801|Clostridia,261H6@186807|Peptococcaceae	186801|Clostridia	K	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384,HTH_psq,SEC-C
CMS3_k127_3600988_1	926569.ANT_14370	3.609e-87	298.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
CMS3_k127_3601265_0	497964.CfE428DRAFT_3190	2.543e-171	554.0	COG1056@1|root,COG1056@2|Bacteria	2|Bacteria	H	cytidyltransferase-related domain	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,Methyltransf_25
CMS3_k127_3601265_2	357808.RoseRS_3001	1.211e-10	68.0	2DRW3@1|root,33DCW@2|Bacteria,2G7E0@200795|Chloroflexi,37627@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
CMS3_k127_3601265_1	765420.OSCT_2565	1.638e-28	132.0	COG1287@1|root,COG1287@2|Bacteria,2GAA0@200795|Chloroflexi,376PD@32061|Chloroflexia	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3627338_6	1128421.JAGA01000001_gene2269	5.322e-84	289.0	COG1028@1|root,COG1028@2|Bacteria,2NQB4@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_3627338_0	1340493.JNIF01000003_gene3441	1.539e-155	514.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,3Y3U8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
CMS3_k127_3627338_1	926569.ANT_02790	8.59e-143	483.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
CMS3_k127_3627338_10	926550.CLDAP_16800	5.625e-32	133.0	COG1418@1|root,COG1418@2|Bacteria,2G9HV@200795|Chloroflexi	200795|Chloroflexi	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_3627338_7	99598.Cal7507_1993	4.444e-69	243.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,1HK54@1161|Nostocales	1117|Cyanobacteria	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
CMS3_k127_3627338_12	926550.CLDAP_12350	1.349e-05	57.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
CMS3_k127_3627338_4	926569.ANT_02430	5.099e-91	305.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3627338_3	526227.Mesil_0256	1.034e-130	463.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
CMS3_k127_3627338_5	395493.BegalDRAFT_0574	1.098e-89	310.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1QWW7@1224|Proteobacteria,1T4BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_3627338_11	298653.Franean1_7074	9.244e-29	133.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria,4ESXW@85013|Frankiales	201174|Actinobacteria	H	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_3627338_8	479434.Sthe_1104	2.772e-50	188.0	COG1877@1|root,COG1877@2|Bacteria,2G6X2@200795|Chloroflexi,27YHH@189775|Thermomicrobia	189775|Thermomicrobia	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
CMS3_k127_3627338_2	479434.Sthe_1953	6.18e-134	445.0	COG0380@1|root,COG0380@2|Bacteria,2G6F8@200795|Chloroflexi,27XTV@189775|Thermomicrobia	189775|Thermomicrobia	G	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
CMS3_k127_3627338_13	644282.Deba_0731	2.828e-05	54.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Transcription factor CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
CMS3_k127_3627338_9	880072.Desac_0960	4.774e-46	173.0	COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria,2MQFB@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	AAA domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
CMS3_k127_3641675_1	445973.CLOBAR_00571	5.07e-23	111.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,25TQ1@186804|Peptostreptococcaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
CMS3_k127_3641675_0	284031.JNXD01000024_gene190	6.858e-31	134.0	COG3608@1|root,COG3608@2|Bacteria,2IC8T@201174|Actinobacteria	201174|Actinobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS3_k127_3641675_2	309801.trd_A0363	6.063e-09	62.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi,27YUW@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS3_k127_3653397_2	756272.Plabr_2401	1.348e-41	158.0	2AK0S@1|root,31AQA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3653397_0	391587.KAOT1_20777	5.489e-46	168.0	2EE2W@1|root,337XH@2|Bacteria,4NT2Z@976|Bacteroidetes,1I4KD@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3653397_1	448385.sce1266	6.854e-44	171.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
CMS3_k127_3653991_9	622637.KE124774_gene2746	1.596e-17	96.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2TRQQ@28211|Alphaproteobacteria,36Z9I@31993|Methylocystaceae	28211|Alphaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_3653991_10	1123368.AUIS01000008_gene2271	2.147e-12	69.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS3_k127_3653991_5	926569.ANT_26550	1.033e-43	169.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
CMS3_k127_3653991_6	1120950.KB892744_gene2818	1.682e-34	136.0	COG1846@1|root,COG1846@2|Bacteria,2IPXE@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS3_k127_3653991_7	420324.KI912086_gene7360	1.393e-32	134.0	COG3678@1|root,COG3678@2|Bacteria,1PZJ1@1224|Proteobacteria,2V2M9@28211|Alphaproteobacteria,1JYPK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3653991_3	1122921.KB898186_gene4954	3.132e-78	274.0	COG1748@1|root,COG1748@2|Bacteria,1V1T1@1239|Firmicutes,4HG5Q@91061|Bacilli,26SRA@186822|Paenibacillaceae	91061|Bacilli	E	Saccharopine dehydrogenase	lyS1	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
CMS3_k127_3653991_8	926569.ANT_26890	3.367e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_3653991_4	644282.Deba_2974	6.261e-55	204.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,42S8U@68525|delta/epsilon subdivisions,2WND3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_3653991_2	880073.Calab_2418	9.4e-84	294.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS3_k127_3653991_1	485913.Krac_12542	2.406e-99	338.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi	200795|Chloroflexi	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3653991_0	224325.AF_2100	1.635e-121	407.0	COG0028@1|root,arCOG01998@2157|Archaea,2XT5F@28890|Euryarchaeota,245VB@183980|Archaeoglobi	28890|Euryarchaeota	E	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_3658752_0	555088.DealDRAFT_2366	2.223e-55	214.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42JMD@68298|Syntrophomonadaceae	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_3662845_0	765420.OSCT_0862	1.661e-131	429.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_3662845_3	1122947.FR7_0853	1.099e-28	122.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4H4WN@909932|Negativicutes	909932|Negativicutes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS3_k127_3662845_2	926569.ANT_31660	1.753e-33	138.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_3662845_1	926569.ANT_31670	1.602e-38	149.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS3_k127_3670898_1	1128421.JAGA01000003_gene3537	1.43e-94	314.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3670898_0	1128421.JAGA01000003_gene3536	8.045e-118	394.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_3670898_3	1173028.ANKO01000112_gene4858	7.767e-12	74.0	2DR31@1|root,339YG@2|Bacteria,1GAVI@1117|Cyanobacteria,1HDY2@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
CMS3_k127_3670898_2	649747.HMPREF0083_00385	7.695e-14	79.0	COG1595@1|root,COG1595@2|Bacteria,1V5UR@1239|Firmicutes,4IQ33@91061|Bacilli,2768T@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3693766_1	1128421.JAGA01000003_gene3678	4.369e-47	183.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS3_k127_3693766_2	765420.OSCT_2895	6.605e-25	113.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
CMS3_k127_3693766_0	570268.ANBB01000040_gene3443	9.958e-53	202.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4EIFG@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3697438_0	402881.Plav_0154	3.565e-150	486.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,1JPSK@119043|Rhodobiaceae	28211|Alphaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3697438_1	485913.Krac_1276	2.693e-09	62.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_370343_0	1125863.JAFN01000001_gene2628	9.531e-89	312.0	COG2197@1|root,COG4191@1|root,COG2197@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_3705565_1	765420.OSCT_1859	3.751e-80	293.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	200795|Chloroflexi	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS3_k127_3705565_0	526225.Gobs_1160	2.024e-98	362.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,TIR_2,WD40
CMS3_k127_3708343_1	207559.Dde_3686	6.217e-98	328.0	COG0451@1|root,COG0451@2|Bacteria,1R95N@1224|Proteobacteria,42QWF@68525|delta/epsilon subdivisions,2WTTT@28221|Deltaproteobacteria,2M9DK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_3708343_0	765420.OSCT_2902	4.338e-172	544.0	COG0451@1|root,COG0451@2|Bacteria,2G7TG@200795|Chloroflexi	200795|Chloroflexi	GM	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS3_k127_3710367_4	585.DR95_1620	5.268e-20	93.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,3Z3I2@583|Proteus	1236|Gammaproteobacteria	K	Cold shock protein domain	cspE	GO:0001072,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008143,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0031564,GO:0043242,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0070717,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	iECW_1372.ECW_m0678,iWFL_1372.ECW_m0678	CSD
CMS3_k127_3710367_2	324602.Caur_0429	1.658e-27	116.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi,375XQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CMS3_k127_3710367_3	999411.HMPREF1092_00949	1.566e-23	105.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,36ESG@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3710367_0	517418.Ctha_0810	5.987e-83	290.0	COG0644@1|root,COG0644@2|Bacteria,1FE1N@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_3710367_1	235909.GK0419	1.888e-46	172.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,1WG50@129337|Geobacillus	91061|Bacilli	T	Low molecular weight phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_3710367_5	345341.KUTG_04140	4.227e-06	56.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3717029_0	926569.ANT_14870	7.27e-310	980.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_3721297_0	926550.CLDAP_24930	5.528e-192	612.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_3721297_1	926550.CLDAP_28700	1.595e-66	236.0	COG0327@1|root,COG0327@2|Bacteria,2G6PK@200795|Chloroflexi	200795|Chloroflexi	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS3_k127_3738606_7	1117943.SFHH103_02496	1.008e-36	155.0	COG1679@1|root,COG1679@2|Bacteria,1NFH4@1224|Proteobacteria,2TTR6@28211|Alphaproteobacteria,4B9RE@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF126,DUF521
CMS3_k127_3738606_8	1158146.KB907122_gene258	3.39e-28	128.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,1WW75@135613|Chromatiales	135613|Chromatiales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_3738606_2	1121403.AUCV01000065_gene4170	7.051e-136	451.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X5IZ@28221|Deltaproteobacteria,2MPF3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS3_k127_3738606_5	523850.TON_0392	2.291e-91	317.0	COG0043@1|root,arCOG01671@2157|Archaea,2XUDW@28890|Euryarchaeota,242S6@183968|Thermococci	183968|Thermococci	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
CMS3_k127_3738606_9	357808.RoseRS_0027	2.035e-17	90.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
CMS3_k127_3738606_3	99598.Cal7507_1324	7.501e-111	376.0	COG1167@1|root,COG1167@2|Bacteria,1G2H6@1117|Cyanobacteria,1HJV0@1161|Nostocales	1117|Cyanobacteria	K	COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
CMS3_k127_3738606_0	926550.CLDAP_00290	1.512e-211	667.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS3_k127_3738606_1	357808.RoseRS_2884	8.078e-193	609.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi,376KP@32061|Chloroflexia	32061|Chloroflexia	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_3738606_4	316274.Haur_1769	3.649e-101	339.0	COG1609@1|root,COG1609@2|Bacteria,2G675@200795|Chloroflexi,376DF@32061|Chloroflexia	32061|Chloroflexia	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_3738606_6	56110.Oscil6304_3191	2.393e-73	257.0	COG0524@1|root,COG0524@2|Bacteria,1G2YU@1117|Cyanobacteria,1HEHA@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_3757950_2	926569.ANT_13850	6.11e-13	76.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_13850|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3757950_1	926569.ANT_13860	5.682e-42	162.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CMS3_k127_3757950_0	926569.ANT_30000	2.738e-194	633.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
CMS3_k127_3758075_0	314285.KT71_18426	5.455e-192	610.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
CMS3_k127_3758075_2	926569.ANT_27650	4.893e-22	99.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS3_k127_3758075_1	1121381.JNIV01000192_gene3472	3.634e-74	260.0	28PB4@1|root,2ZC42@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3768595_2	1121396.KB892900_gene2129	5.928e-27	128.0	COG1657@1|root,COG2374@1|root,COG2931@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG5306@1|root,COG1657@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5306@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
CMS3_k127_3768595_1	1123277.KB893197_gene6111	2.881e-46	190.0	COG3203@1|root,COG4386@1|root,COG3203@2|Bacteria,COG4386@2|Bacteria,4PM6S@976|Bacteroidetes,47Y33@768503|Cytophagia	976|Bacteroidetes	M	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_3768595_0	1123277.KB893197_gene6105	2.181e-132	451.0	COG1520@1|root,COG3266@1|root,COG1520@2|Bacteria,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,47QPM@768503|Cytophagia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_3768748_0	1174528.JH992890_gene610	6.179e-180	586.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,Thioesterase
CMS3_k127_3768917_12	1229487.AMYW01000027_gene2790	2.114e-17	91.0	COG3064@1|root,COG3409@1|root,COG3064@2|Bacteria,COG3409@2|Bacteria,4NR0W@976|Bacteroidetes,1I8YH@117743|Flavobacteriia,2P0IZ@237|Flavobacterium	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,PG_binding_1
CMS3_k127_3768917_9	864051.BurJ1DRAFT_3804	4.587e-44	168.0	COG0727@1|root,COG0727@2|Bacteria,1N1SQ@1224|Proteobacteria,2W4A3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
CMS3_k127_3768917_0	42256.RradSPS_0358	1.853e-144	490.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_3768917_2	926550.CLDAP_13900	3.951e-124	413.0	COG0151@1|root,COG0151@2|Bacteria,2G5ZE@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Phosphoribosylglycinamide synthetase	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS3_k127_3768917_11	926569.ANT_30850	7.647e-26	109.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
CMS3_k127_3768917_6	1122604.JONR01000048_gene1007	4.794e-62	224.0	COG4221@1|root,COG4221@2|Bacteria,1QXBX@1224|Proteobacteria,1T4IE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
CMS3_k127_3768917_3	84531.JMTZ01000030_gene152	6.073e-123	401.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales	135614|Xanthomonadales	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS3_k127_3768917_5	1273538.G159_13075	7.03e-100	335.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,26D3B@186818|Planococcaceae	91061|Bacilli	H	Lipoate-protein ligase	lplJ	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
CMS3_k127_3768917_13	743719.PaelaDRAFT_1679	3.987e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,1V589@1239|Firmicutes,4HHV5@91061|Bacilli,26SN2@186822|Paenibacillaceae	91061|Bacilli	KT	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP5	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Trans_reg_C
CMS3_k127_3768917_14	1173028.ANKO01000065_gene5619	3.197e-07	60.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,1H919@1150|Oscillatoriales	1117|Cyanobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
CMS3_k127_3768917_8	926569.ANT_31200	5.807e-49	198.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_3768917_10	1519464.HY22_00075	1.853e-29	136.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1FEZK@1090|Chlorobi	1090|Chlorobi	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
CMS3_k127_3768917_1	316274.Haur_1174	1.626e-132	431.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi,375EF@32061|Chloroflexia	32061|Chloroflexia	H	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
CMS3_k127_3768917_4	926550.CLDAP_35970	2.72e-110	369.0	COG1820@1|root,COG1820@2|Bacteria,2G6HC@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_3768917_7	316274.Haur_1181	6.013e-51	193.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi,375NG@32061|Chloroflexia	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_377506_10	1392487.JIAD01000001_gene1430	1.183e-07	56.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,25V9W@186806|Eubacteriaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS3_k127_377506_8	649638.Trad_0506	1.122e-36	146.0	COG1132@1|root,COG1132@2|Bacteria,1WISJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_377506_2	1045855.DSC_02185	1.704e-146	480.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1X2ZC@135614|Xanthomonadales	135614|Xanthomonadales	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_377506_7	926569.ANT_23470	1.54e-60	212.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi	200795|Chloroflexi	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS3_k127_377506_0	926569.ANT_23480	0.0	1085.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
CMS3_k127_377506_11	1192034.CAP_3089	6.061e-06	60.0	COG0402@1|root,COG2374@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria,2YUGP@29|Myxococcales	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,DUF4215,LTD,TSP_3
CMS3_k127_377506_5	926550.CLDAP_10010	6.43e-109	384.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,Sulfotransfer_3
CMS3_k127_377506_1	316274.Haur_3139	2.561e-213	672.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,375IW@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_377506_3	357808.RoseRS_0088	5.743e-146	475.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi,375DN@32061|Chloroflexia	32061|Chloroflexia	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_377506_4	383372.Rcas_0178	9.062e-113	373.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_377506_6	1125863.JAFN01000001_gene2355	6.01e-62	245.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1PFJ7@1224|Proteobacteria,42WVE@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_377506_9	1408433.JHXV01000010_gene529	3.461e-34	154.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,4NIDX@976|Bacteroidetes,1I0AY@117743|Flavobacteriia,2PBAP@246874|Cryomorphaceae	976|Bacteroidetes	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS3_k127_379590_2	309799.DICTH_1883	2.994e-59	208.0	arCOG06481@1|root,2ZB4E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_379590_0	272123.Anacy_2457	9.166e-205	692.0	COG1122@1|root,COG2319@1|root,COG1122@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HQSK@1161|Nostocales	1117|Cyanobacteria	P	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
CMS3_k127_379590_5	765420.OSCT_1375	2.313e-41	178.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi	200795|Chloroflexi	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
CMS3_k127_379590_1	765420.OSCT_3185	5.469e-96	332.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2G86V@200795|Chloroflexi,374S2@32061|Chloroflexia	32061|Chloroflexia	KLT	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS3_k127_379590_4	1122182.KB903833_gene5605	5.569e-48	185.0	COG5324@1|root,COG5324@2|Bacteria,2I44F@201174|Actinobacteria,4DMJH@85008|Micromonosporales	201174|Actinobacteria	T	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_lig_T4_1
CMS3_k127_379590_3	398525.KB900701_gene516	4.98e-51	187.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2U0FG@28211|Alphaproteobacteria,3JX5H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
CMS3_k127_379590_6	1449350.OCH239_05120	1.937e-12	69.0	COG2801@1|root,COG2801@2|Bacteria,1N4JW@1224|Proteobacteria,2UEHC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21
CMS3_k127_3805771_2	246194.CHY_0715	0.0001541	48.0	COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,24QKP@186801|Clostridia,42GK0@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulator, CopG family	-	-	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
CMS3_k127_3805771_0	1123023.JIAI01000007_gene1963	2.454e-87	299.0	COG0404@1|root,COG0446@1|root,COG4583@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,COG4583@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS3_k127_3805771_1	1122201.AUAZ01000034_gene3503	1.31e-19	95.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS3_k127_3810014_6	861299.J421_0471	1.048e-59	219.0	COG2010@1|root,COG2010@2|Bacteria,1ZUJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3810014_16	251221.35211983	7.967e-05	53.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_3810014_11	485913.Krac_5098	1.009e-31	130.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS3_k127_3810014_2	926560.KE387023_gene1202	4.065e-133	437.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_3810014_15	5786.XP_003291844.1	1.902e-05	57.0	295V0@1|root,2RCTK@2759|Eukaryota,3XBE0@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3810014_12	278957.ABEA03000182_gene1978	2.427e-26	126.0	COG2730@1|root,COG2730@2|Bacteria,46XJ7@74201|Verrucomicrobia,3K99G@414999|Opitutae	414999|Opitutae	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CMS3_k127_3810014_3	66429.JOFL01000006_gene1938	2.09e-80	294.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_3810014_13	926560.KE387027_gene552	3.887e-24	106.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
CMS3_k127_3810014_4	357808.RoseRS_2229	5.244e-71	270.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3810014_10	500153.JOEK01000014_gene5612	1.065e-45	190.0	COG3828@1|root,COG5434@1|root,COG3828@2|Bacteria,COG5434@2|Bacteria,2GJW0@201174|Actinobacteria	201174|Actinobacteria	M	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_99
CMS3_k127_3810014_9	768671.ThimaDRAFT_1176	3.448e-47	173.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria,1X24R@135613|Chromatiales	135613|Chromatiales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_3810014_7	1457250.BBMO01000002_gene2464	4.513e-56	204.0	COG0500@1|root,arCOG04734@2157|Archaea,2XWDH@28890|Euryarchaeota,23V0A@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_3810014_14	767817.Desgi_0117	1.842e-05	55.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1V9XU@1239|Firmicutes,24NW6@186801|Clostridia,262DR@186807|Peptococcaceae	186801|Clostridia	M	PFAM L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
CMS3_k127_3810014_1	926550.CLDAP_11980	1.892e-133	443.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
CMS3_k127_3810014_5	926569.ANT_06850	1.377e-61	228.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
CMS3_k127_3810014_0	926550.CLDAP_11960	2.444e-152	494.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi	200795|Chloroflexi	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS3_k127_3810014_8	1382356.JQMP01000003_gene2514	1.765e-49	182.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,27Y7W@189775|Thermomicrobia	189775|Thermomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS3_k127_3818462_2	696281.Desru_2695	9.909e-09	60.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_8,FrhB_FdhB_C
CMS3_k127_3818462_1	1125863.JAFN01000001_gene1777	3.286e-62	216.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42TFE@68525|delta/epsilon subdivisions,2WPDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS3_k127_3818462_0	760568.Desku_0188	3.057e-84	294.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885,ko:K16886	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,FlpD,Pyr_redox_2
CMS3_k127_3827364_1	391625.PPSIR1_31478	1.23e-28	120.0	COG0566@1|root,COG0566@2|Bacteria,1Q9ZD@1224|Proteobacteria,42VPG@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	rRNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CMS3_k127_3827364_0	1499967.BAYZ01000102_gene3573	2.498e-52	201.0	COG3979@1|root,COG3979@2|Bacteria	2|Bacteria	S	chitin catabolic process	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.2.1.14,3.2.1.17	ko:K01183,ko:K03933,ko:K13381	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	AA10,CBM15,CBM73,GH18	-	CBM_5_12,DUF5011,LPMO_10,Peptidase_M60
CMS3_k127_3828573_1	1144275.COCOR_03695	2.15e-62	241.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3828573_3	530564.Psta_0613	1.036e-19	105.0	COG4655@1|root,COG4655@2|Bacteria,2J54T@203682|Planctomycetes	203682|Planctomycetes	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3828573_0	489825.LYNGBM3L_31790	1.612e-76	265.0	28N1N@1|root,2ZB7Q@2|Bacteria,1G91X@1117|Cyanobacteria,1HDK0@1150|Oscillatoriales	1117|Cyanobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_3828573_2	1128421.JAGA01000002_gene1640	4.166e-27	112.0	COG2259@1|root,COG2259@2|Bacteria,2NQ4C@2323|unclassified Bacteria	2|Bacteria	S	DoxX	-	-	1.8.5.2	ko:K15977,ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
CMS3_k127_3828897_2	926569.ANT_25860	1.172e-76	270.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi	200795|Chloroflexi	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2,eRF1_3
CMS3_k127_3828897_4	383372.Rcas_2624	4.616e-15	76.0	2EPAC@1|root,33GX3@2|Bacteria,2GB3X@200795|Chloroflexi,377VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3828897_3	926569.ANT_05550	8.791e-37	155.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027,ko:K15770	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_1,SBP_bac_8
CMS3_k127_3828897_1	765420.OSCT_1801	1.752e-85	299.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS3_k127_3828897_0	926569.ANT_31260	2.152e-171	550.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_383050_4	1196323.ALKF01000192_gene3207	2.668e-13	72.0	COG2378@1|root,COG2378@2|Bacteria,1V1XQ@1239|Firmicutes,4HGPD@91061|Bacilli,274WB@186822|Paenibacillaceae	91061|Bacilli	K	WYL domain	yobV13	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS3_k127_383050_5	91464.S7335_5409	1.566e-05	56.0	COG2319@1|root,COG2319@2|Bacteria,1G208@1117|Cyanobacteria,1H082@1129|Synechococcus	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_383050_0	926560.KE387023_gene1969	3.142e-134	436.0	COG3396@1|root,COG3396@2|Bacteria,1WI17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
CMS3_k127_383050_3	1289387.AUKW01000003_gene2290	1.291e-18	89.0	COG3460@1|root,COG3460@2|Bacteria,2IKMJ@201174|Actinobacteria	201174|Actinobacteria	Q	Phenylacetate-CoA oxygenase	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
CMS3_k127_383050_1	649638.Trad_1147	9.281e-76	263.0	COG3396@1|root,COG3396@2|Bacteria,1WI5D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Phenylacetate-CoA oxygenase, PaaI subunit	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
CMS3_k127_383050_2	1237149.C900_04824	4.311e-45	170.0	COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes	976|Bacteroidetes	L	Phenylacetate-CoA oxygenase	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
CMS3_k127_3833938_7	243365.CV_2086	0.0001992	49.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VGZU@28216|Betaproteobacteria,2KQNB@206351|Neisseriales	206351|Neisseriales	C	Dehydrogenase	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_3833938_5	1206720.BAFQ01000297_gene6658	9.092e-09	63.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria,4G2S5@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
CMS3_k127_3833938_6	1521187.JPIM01000004_gene3074	2.846e-07	64.0	COG0631@1|root,COG0631@2|Bacteria,2G72P@200795|Chloroflexi,374Z2@32061|Chloroflexia	32061|Chloroflexia	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3833938_0	926550.CLDAP_09650	1.218e-94	334.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
CMS3_k127_3833938_3	926550.CLDAP_09640	5.435e-34	137.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
CMS3_k127_3833938_4	351160.RCIX134	3.819e-14	79.0	arCOG05710@1|root,arCOG05710@2157|Archaea,2Y58V@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3833938_2	926569.ANT_20590	1.114e-46	182.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
CMS3_k127_3833938_1	1128421.JAGA01000003_gene3655	6.019e-83	312.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CMS3_k127_3841761_0	1121937.AUHJ01000008_gene2040	7.193e-41	161.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,46A4P@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	dcyD	-	4.4.1.15,4.4.1.25	ko:K05396,ko:K17950	ko00270,map00270	-	R01874,R07634	RC00382,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
CMS3_k127_3841761_1	221288.JH992900_gene60	2.92e-27	115.0	COG2402@1|root,COG2402@2|Bacteria,1GKD0@1117|Cyanobacteria,1JMGG@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS3_k127_3841761_3	913865.DOT_2774	1.565e-05	51.0	COG2161@1|root,COG2161@2|Bacteria,1V7IT@1239|Firmicutes,24MJ6@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
CMS3_k127_3841761_2	386456.JQKN01000005_gene436	2.1e-21	96.0	COG2303@1|root,arCOG02232@2157|Archaea,2Y89C@28890|Euryarchaeota,23NTI@183925|Methanobacteria	183925|Methanobacteria	E	PFAM Glucose-methanol-choline oxidoreductase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,GMC_oxred_C,GMC_oxred_N
CMS3_k127_3843894_0	306281.AJLK01000201_gene525	8.477e-31	134.0	COG1807@1|root,COG1807@2|Bacteria,1G4QV@1117|Cyanobacteria	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3856614_1	1128421.JAGA01000003_gene3091	1.23e-45	188.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_3856614_0	926560.KE387023_gene3263	6.364e-109	385.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_3856614_3	926569.ANT_15080	2.861e-21	108.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
CMS3_k127_3856614_2	1232410.KI421426_gene1319	5.333e-27	116.0	COG0662@1|root,COG0662@2|Bacteria,1QYNW@1224|Proteobacteria	1224|Proteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_3856614_5	575540.Isop_1566	1.105e-05	57.0	COG1562@1|root,COG1562@2|Bacteria,2IZF8@203682|Planctomycetes	203682|Planctomycetes	I	Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS3_k127_3858823_1	471854.Dfer_0264	1.133e-19	104.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CMS3_k127_3863805_2	926550.CLDAP_27950	1.981e-125	409.0	COG1175@1|root,COG1175@2|Bacteria,2G6P7@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS3_k127_3863805_3	926550.CLDAP_27940	6.628e-116	381.0	COG0395@1|root,COG0395@2|Bacteria,2G6H2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS3_k127_3863805_1	926550.CLDAP_27930	1.657e-197	625.0	COG1653@1|root,COG1653@2|Bacteria,2G6V5@200795|Chloroflexi	200795|Chloroflexi	G	extracellular solute-binding protein, family 1	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
CMS3_k127_3863805_4	543728.Vapar_3673	2.124e-42	169.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2VJKU@28216|Betaproteobacteria,4AB6Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_3863805_0	926550.CLDAP_27920	1.909e-219	706.0	COG1858@1|root,COG2133@1|root,COG1858@2|Bacteria,COG2133@2|Bacteria,2G989@200795|Chloroflexi	200795|Chloroflexi	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_3887951_2	1121377.KB906402_gene3344	1.437e-17	97.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_21,META
CMS3_k127_3887951_6	1121380.JNIW01000012_gene1892	2.129e-09	68.0	COG0631@1|root,COG0631@2|Bacteria,1WIBX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_3887951_3	485913.Krac_0968	8.687e-15	81.0	COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi	2|Bacteria	S	SPTR D1C1B9 DinB family protein	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
CMS3_k127_3887951_0	904306.HMPREF9192_0440	3.261e-70	246.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli	91061|Bacilli	V	ABC transporter, ATP-binding protein	salX	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_3887951_4	1380390.JIAT01000009_gene1516	1.196e-14	89.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4CU4J@84995|Rubrobacteria	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_3887951_5	690850.Desaf_0397	5.732e-10	72.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MGB8@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS3_k127_3887951_1	96561.Dole_1902	5.391e-31	126.0	COG1848@1|root,COG1848@2|Bacteria,1N5DS@1224|Proteobacteria,43BCN@68525|delta/epsilon subdivisions,2X6RK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS3_k127_3903709_3	1128421.JAGA01000002_gene821	6.341e-77	274.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
CMS3_k127_3903709_1	926550.CLDAP_31460	3.64e-94	317.0	COG1216@1|root,COG1216@2|Bacteria,2G5U8@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
CMS3_k127_3903709_0	926550.CLDAP_31450	2.62e-128	425.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G5Y5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_3903709_2	926569.ANT_25070	2.882e-88	302.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
CMS3_k127_3920674_0	383372.Rcas_2190	2.65e-168	542.0	COG0076@1|root,COG0076@2|Bacteria,2GAD1@200795|Chloroflexi,376VF@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase class V	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
CMS3_k127_392298_1	1121859.KB890739_gene2736	2.514e-84	297.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_392298_2	1173028.ANKO01000041_gene3209	4.899e-52	192.0	COG0657@1|root,COG0657@2|Bacteria,1G3P7@1117|Cyanobacteria,1H8QH@1150|Oscillatoriales	1117|Cyanobacteria	I	Alpha beta hydrolase fold	-	-	3.1.1.83	ko:K01066,ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_392298_3	2074.JNYD01000010_gene963	5.139e-13	73.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4DYGY@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
CMS3_k127_392298_0	1231185.BAMP01000093_gene2457	3.682e-86	299.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1062 Zn-dependent alcohol dehydrogenases, class III	-	-	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3929572_0	316274.Haur_4393	6.641e-159	509.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_3929572_1	316274.Haur_4394	1.348e-146	481.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
CMS3_k127_3931597_1	338969.Rfer_2227	5.757e-10	72.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VPH8@28216|Betaproteobacteria,4AF3Y@80864|Comamonadaceae	28216|Betaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_3931597_0	1403819.BATR01000022_gene806	1.879e-73	265.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_3937456_0	526227.Mesil_0256	2.355e-138	456.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
CMS3_k127_3937456_1	479434.Sthe_2194	8.622e-13	74.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,T4_deiodinase
CMS3_k127_3938983_0	926569.ANT_29650	2.143e-76	271.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_3938983_1	926550.CLDAP_12010	1.516e-48	182.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_12010|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3938983_2	1089550.ATTH01000001_gene509	4.08e-44	168.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1FJB8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_3945327_0	1121405.dsmv_1128	0.0	1154.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MIS4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
CMS3_k127_3945327_1	518766.Rmar_0555	1.647e-56	201.0	COG3265@1|root,COG3265@2|Bacteria,4NQI4@976|Bacteroidetes	976|Bacteroidetes	G	TIGRFAM carbohydrate kinase, thermoresistant glucokinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	SKI
CMS3_k127_3955096_0	926550.CLDAP_38270	4.658e-33	147.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
CMS3_k127_3955096_1	7955.ENSDARP00000112831	0.0007	43.0	KOG1164@1|root,KOG1164@2759|Eukaryota,38BMB@33154|Opisthokonta,3BDMM@33208|Metazoa,3CSY0@33213|Bilateria,47ZDY@7711|Chordata,492WS@7742|Vertebrata,49SFR@7898|Actinopterygii	33208|Metazoa	T	Vaccinia related kinase 3	VRK3	GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010646,GO:0010648,GO:0010921,GO:0010922,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019902,GO:0019903,GO:0022603,GO:0022604,GO:0023051,GO:0023057,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032516,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0036211,GO:0042325,GO:0042326,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043408,GO:0043409,GO:0043412,GO:0043666,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045936,GO:0045937,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051246,GO:0051247,GO:0051248,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070372,GO:0070373,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1902531,GO:1902532	2.7.11.1	ko:K08816	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pkinase_Tyr,zinc_ribbon_2
CMS3_k127_3955719_0	926550.CLDAP_19470	1.862e-109	375.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_3955719_1	99598.Cal7507_5818	1.708e-41	159.0	COG1017@1|root,COG2114@1|root,COG5000@1|root,COG1017@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria,1G2WP@1117|Cyanobacteria,1HKCN@1161|Nostocales	1117|Cyanobacteria	CT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Globin,Guanylate_cyc,HAMP,dCache_1
CMS3_k127_3955719_2	1121897.AUGO01000002_gene2407	3.924e-12	78.0	COG3210@1|root,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_396141_1	1038862.KB893848_gene5731	0.0001212	48.0	COG2133@1|root,COG2133@2|Bacteria,1R8DY@1224|Proteobacteria,2U4BZ@28211|Alphaproteobacteria,3JXE5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_396141_0	357808.RoseRS_0892	2.33e-19	96.0	COG2319@1|root,COG2319@2|Bacteria,2G8RB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS3_k127_3968429_0	204669.Acid345_2395	2.876e-143	472.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
CMS3_k127_3968429_4	1123242.JH636435_gene2023	2.542e-11	65.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_3968429_3	314271.RB2654_06719	2.307e-55	217.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_3968429_2	760192.Halhy_0626	1.877e-119	402.0	COG0654@1|root,COG0654@2|Bacteria,4NFUC@976|Bacteroidetes	976|Bacteroidetes	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_3968429_1	383372.Rcas_3701	1.755e-130	456.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS3_k127_3969560_0	63737.Npun_F0966	8.49e-164	550.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS3_k127_3969560_2	926550.CLDAP_05380	2.667e-29	123.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CMS3_k127_3969560_1	981384.AEYW01000006_gene2983	2.324e-131	430.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
CMS3_k127_3969560_3	311424.DhcVS_118	5.693e-25	114.0	COG3568@1|root,COG3568@2|Bacteria,2G7ER@200795|Chloroflexi,34CM1@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_3969905_4	479434.Sthe_2481	1.925e-79	273.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	189775|Thermomicrobia	EQ	Hydantoinaseoxoprolinase domain protein	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS3_k127_3969905_0	557598.LHK_00777	1.677e-194	620.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KPJ8@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS3_k127_3969905_7	882082.SaccyDRAFT_0408	5.648e-51	192.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4DY0P@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_3969905_8	383372.Rcas_2986	5.524e-41	160.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi,377GE@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS3_k127_3969905_12	112098.XP_008621355.1	0.0008219	51.0	28I44@1|root,2QQEI@2759|Eukaryota	2759|Eukaryota	S	regulation of centriole replication	CEP76	GO:0000086,GO:0000278,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005814,GO:0005815,GO:0005829,GO:0005856,GO:0006996,GO:0007049,GO:0007346,GO:0008150,GO:0009987,GO:0010389,GO:0010564,GO:0010824,GO:0015630,GO:0016043,GO:0022402,GO:0022406,GO:0022607,GO:0030030,GO:0030031,GO:0032886,GO:0032991,GO:0033043,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0046599,GO:0046605,GO:0050789,GO:0050794,GO:0051128,GO:0051179,GO:0051493,GO:0051640,GO:0051641,GO:0051726,GO:0060271,GO:0065007,GO:0070507,GO:0070925,GO:0071840,GO:0097711,GO:0120031,GO:0120036,GO:0140056,GO:1901987,GO:1901990,GO:1902115,GO:1902749,GO:1903047	-	ko:K16457	-	-	-	-	ko00000,ko03036	-	-	-	CEP76-C2
CMS3_k127_3969905_10	562970.Btus_2079	4.236e-27	116.0	COG0454@1|root,COG0456@2|Bacteria,1V562@1239|Firmicutes,4HMAE@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_3969905_5	765420.OSCT_3029	4.797e-64	240.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS3_k127_3969905_6	266265.Bxe_A2751	1.113e-52	196.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2VK8V@28216|Betaproteobacteria,1K1J7@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Coenzyme A transferase	gctA	-	2.8.3.12,2.8.3.5	ko:K01028,ko:K01039	ko00072,ko00280,ko00643,ko00650,ko01120,map00072,map00280,map00643,map00650,map01120	-	R00410,R04000,R05509	RC00012,RC00014,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS3_k127_3969905_11	525904.Tter_1169	4.065e-05	55.0	COG0598@1|root,COG0598@2|Bacteria,2NQIW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_3969905_9	266265.Bxe_A2752	7.162e-35	147.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2VKG3@28216|Betaproteobacteria,1K3YG@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyl CoA acetate 3-ketoacid CoA	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_3969905_2	1385511.N783_15970	9.606e-155	508.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,2Y9FG@289201|Pontibacillus	91061|Bacilli	IQ	Activates fatty acids by binding to coenzyme A	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3969905_3	937777.Deipe_2010	9.959e-99	329.0	COG1028@1|root,COG1028@2|Bacteria,1WIJY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS3_k127_3969905_1	118163.Ple7327_1947	7.348e-160	512.0	COG4663@1|root,COG4663@2|Bacteria,1G1BA@1117|Cyanobacteria,3VHWR@52604|Pleurocapsales	1117|Cyanobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0015849,GO:0022857,GO:0031317,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1903825,GO:1990351	-	-	-	-	-	-	-	-	-	-	DctP
CMS3_k127_3973742_0	1085623.GNIT_1475	2.197e-147	488.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,1RMPG@1236|Gammaproteobacteria,464P1@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0514 Superfamily II DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_3973742_1	1146883.BLASA_1782	1.346e-44	183.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
CMS3_k127_3973742_2	435591.BDI_0281	2.846e-16	81.0	COG1983@1|root,COG1983@2|Bacteria,4NX1N@976|Bacteroidetes,2FUW2@200643|Bacteroidia	976|Bacteroidetes	KT	PspC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PspC
CMS3_k127_3975747_0	1242864.D187_000739	1.449e-138	446.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,42QSZ@68525|delta/epsilon subdivisions,2WN50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
CMS3_k127_3975747_2	877421.AUJT01000001_gene1759	2.246e-06	61.0	2EEXI@1|root,338QW@2|Bacteria,1VD7C@1239|Firmicutes,24PDV@186801|Clostridia,27NFC@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3975747_1	203908.EGG03565	1.974e-15	90.0	KOG4351@1|root,KOG4351@2759|Eukaryota	2759|Eukaryota	S	ubiquitin binding	NBR1	GO:0000407,GO:0001932,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005776,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0016043,GO:0016236,GO:0016604,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0030278,GO:0030279,GO:0030500,GO:0031323,GO:0031399,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032182,GO:0032268,GO:0032872,GO:0042325,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043408,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045595,GO:0045596,GO:0045667,GO:0045668,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051019,GO:0051093,GO:0051171,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051259,GO:0060255,GO:0061919,GO:0065003,GO:0065007,GO:0070013,GO:0070167,GO:0070302,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0097708,GO:1902531,GO:2000026	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1,ZZ
CMS3_k127_3985827_0	314271.RB2654_06724	5.818e-35	147.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_3987614_0	1121378.KB899713_gene742	8.737e-57	209.0	COG0122@1|root,COG0122@2|Bacteria,1WMVE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
CMS3_k127_3987614_1	1379698.RBG1_1C00001G0251	2.329e-48	181.0	2DEGI@1|root,2ZMXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3987614_2	1173026.Glo7428_3455	1.512e-30	126.0	COG1846@1|root,COG1846@2|Bacteria,1G6FP@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
CMS3_k127_3987614_3	1040989.AWZU01000023_gene4843	3.096e-15	82.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
CMS3_k127_3992833_9	926550.CLDAP_07570	9.28e-10	64.0	COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_3992833_7	795797.C497_10463	1.491e-45	180.0	COG0558@1|root,arCOG00672@2157|Archaea,2XZ24@28890|Euryarchaeota,23X7M@183963|Halobacteria	183963|Halobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_3992833_3	1174528.JH992898_gene4701	2.117e-68	251.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
CMS3_k127_3992833_10	870187.Thini_4357	1.25e-09	70.0	COG1028@1|root,COG3405@1|root,COG1028@2|Bacteria,COG3405@2|Bacteria,1MWC8@1224|Proteobacteria,1S1X8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS3_k127_3992833_8	926550.CLDAP_02740	2.279e-22	111.0	COG1787@1|root,COG1787@2|Bacteria,2G7E4@200795|Chloroflexi	200795|Chloroflexi	V	PFAM restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat,SH3_3
CMS3_k127_3992833_5	926569.ANT_18330	5.961e-49	180.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS3_k127_3992833_1	479434.Sthe_0827	1.045e-169	552.0	COG0613@1|root,COG2865@1|root,COG0613@2|Bacteria,COG2865@2|Bacteria,2G5UU@200795|Chloroflexi	200795|Chloroflexi	K	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,PHP
CMS3_k127_3992833_11	450851.PHZ_c2211	8.574e-08	59.0	COG0784@1|root,COG0784@2|Bacteria,1N0NS@1224|Proteobacteria,2TV2S@28211|Alphaproteobacteria,2KGN1@204458|Caulobacterales	204458|Caulobacterales	T	chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_3992833_4	926550.CLDAP_32540	1.901e-55	203.0	COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi	200795|Chloroflexi	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS3_k127_3992833_0	330214.NIDE1289	3.141e-283	886.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS3_k127_3992833_2	926550.CLDAP_22640	2.163e-81	284.0	COG0189@1|root,COG0189@2|Bacteria,2G864@200795|Chloroflexi	200795|Chloroflexi	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3992833_6	926550.CLDAP_17410	4.738e-46	176.0	COG0438@1|root,COG0438@2|Bacteria,2G8BD@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
CMS3_k127_3992833_12	67315.JOBD01000018_gene7268	1.468e-07	62.0	COG0644@1|root,COG0644@2|Bacteria,2I301@201174|Actinobacteria	201174|Actinobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,FAD_oxidored
CMS3_k127_4001831_3	1382306.JNIM01000001_gene2945	3.727e-46	178.0	COG1397@1|root,COG1397@2|Bacteria,2G7F9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ADP-ribosylation Crystallin J1	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
CMS3_k127_4001831_1	1303518.CCALI_02548	2.351e-63	228.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	Macro,VWA
CMS3_k127_4001831_0	635013.TherJR_0214	2.502e-101	338.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS3_k127_4001831_2	765420.OSCT_0762	7.987e-51	192.0	COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS3_k127_40159_2	452637.Oter_2022	7.46e-21	94.0	COG1028@1|root,COG1028@2|Bacteria	452637.Oter_2022|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_40159_1	1137268.AZXF01000012_gene3530	6.187e-42	163.0	2C1XE@1|root,301BZ@2|Bacteria,2IGAE@201174|Actinobacteria,4EJ8U@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_40159_0	1192034.CAP_5739	1.149e-103	353.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZJK@68525|delta/epsilon subdivisions,2WV14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_401957_1	485913.Krac_6485	1.574e-30	126.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
CMS3_k127_401957_0	479435.Kfla_5382	3.601e-39	157.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
CMS3_k127_4031910_1	926549.KI421517_gene780	2.102e-46	170.0	2D0TH@1|root,32T97@2|Bacteria,4NQFA@976|Bacteroidetes,47QF9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4031910_0	1254432.SCE1572_09155	8.733e-86	291.0	COG0454@1|root,COG0456@2|Bacteria,1NGUX@1224|Proteobacteria,43ADU@68525|delta/epsilon subdivisions,2X5TS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4031910_2	1522072.IL54_3474	1.636e-20	97.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria,2K5MI@204457|Sphingomonadales	204457|Sphingomonadales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4036551_4	926569.ANT_29910	1.284e-37	160.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi	200795|Chloroflexi	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTPase_1
CMS3_k127_4036551_5	203122.Sde_0382	3.841e-32	134.0	2DBZ7@1|root,2ZBZQ@2|Bacteria,1MYV3@1224|Proteobacteria,1S6NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4253
CMS3_k127_4036551_1	926550.CLDAP_05920	2.628e-169	548.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_4036551_3	671143.DAMO_1601	3.005e-61	220.0	COG1526@1|root,COG1526@2|Bacteria,2NPF9@2323|unclassified Bacteria	2|Bacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ,NTP_transf_3
CMS3_k127_4036551_2	926550.CLDAP_05930	1.221e-86	292.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,cNMP_binding
CMS3_k127_4036551_0	926550.CLDAP_06400	4.612e-253	801.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_4048877_11	316067.Geob_0814	0.0002418	49.0	COG1361@1|root,COG1520@1|root,COG1657@1|root,COG4257@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1657@2|Bacteria,COG4257@2|Bacteria,COG4733@2|Bacteria,1QYWJ@1224|Proteobacteria,43CDC@68525|delta/epsilon subdivisions,2X7P6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_4048877_0	765420.OSCT_1468	1.814e-107	361.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_4048877_4	1254432.SCE1572_07840	2.112e-47	176.0	COG1720@1|root,COG1720@2|Bacteria,1MYVG@1224|Proteobacteria,42N6M@68525|delta/epsilon subdivisions,2WPY9@28221|Deltaproteobacteria,2Z0U5@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0066	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,UPF0066
CMS3_k127_4048877_5	266779.Meso_2460	1.236e-45	174.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_11,Methyltransf_25
CMS3_k127_4048877_2	765420.OSCT_1686	3.49e-91	313.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_4048877_1	765420.OSCT_1688	1.295e-103	348.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_4048877_6	301.JNHE01000004_gene1755	4.217e-15	83.0	28KNE@1|root,2ZA6M@2|Bacteria,1R499@1224|Proteobacteria,1RZKQ@1236|Gammaproteobacteria,1YJBZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
CMS3_k127_4048877_7	1120948.KB903240_gene4171	7.052e-11	70.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	GntR,NUDIX
CMS3_k127_4048877_3	1132509.C447_03481	5.349e-58	208.0	COG1335@1|root,arCOG01943@2157|Archaea,2XWJY@28890|Euryarchaeota,23V5P@183963|Halobacteria	183963|Halobacteria	Q	COG1335 Amidases related to nicotinamidase	entB1	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS3_k127_4050446_0	1499967.BAYZ01000163_gene6584	4.733e-106	376.0	COG0457@1|root,COG0470@1|root,COG0457@2|Bacteria,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	AAA,AAA_22,TIR_2
CMS3_k127_4050446_1	367299.JOEE01000001_gene1743	1.88e-07	58.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4FGN8@85021|Intrasporangiaceae	201174|Actinobacteria	T	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4054875_0	1167006.UWK_01677	1.434e-82	288.0	COG0477@1|root,COG2814@2|Bacteria,1QWMM@1224|Proteobacteria,42PZZ@68525|delta/epsilon subdivisions,2WJ1J@28221|Deltaproteobacteria,2MIYY@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS3_k127_4054875_1	765420.OSCT_1537	2.576e-68	246.0	COG0460@1|root,COG0460@2|Bacteria,2G8BZ@200795|Chloroflexi,376ET@32061|Chloroflexia	32061|Chloroflexia	E	PFAM homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
CMS3_k127_4055639_2	316274.Haur_0947	1.631e-14	77.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12,Trans_reg_C
CMS3_k127_4055639_0	309801.trd_A0070	4.945e-46	187.0	COG3848@1|root,COG3848@2|Bacteria	2|Bacteria	GT	kinase activity	yvkC	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS3_k127_4055639_1	1078020.KEK_00860	5.38e-32	131.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,236PX@1762|Mycobacteriaceae	201174|Actinobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS3_k127_4056837_0	1307761.L21SP2_0103	4.167e-159	520.0	COG0366@1|root,COG0366@2|Bacteria,2J6AH@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Alpha amylase, catalytic domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
CMS3_k127_4056837_1	926550.CLDAP_04740	7.748e-82	281.0	COG3833@1|root,COG3833@2|Bacteria,2G8IJ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
CMS3_k127_4062742_1	926569.ANT_19070	6.369e-83	284.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
CMS3_k127_4062742_3	1123508.JH636442_gene3856	0.000302	48.0	2B9HV@1|root,322W0@2|Bacteria,2IZR4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4062742_2	926569.ANT_23030	5.89e-42	170.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS3_k127_4062742_0	926569.ANT_23020	5.278e-86	309.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_406346_0	867845.KI911784_gene2814	9.91e-90	316.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3759M@32061|Chloroflexia	32061|Chloroflexia	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_406346_2	926569.ANT_28280	5.395e-28	114.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS3_k127_406346_1	1444306.JFZC01000039_gene609	2.28e-34	138.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,26NIW@186821|Sporolactobacillaceae	91061|Bacilli	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS3_k127_4064368_5	1479239.JQMU01000001_gene2284	3.972e-14	74.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2K37J@204457|Sphingomonadales	204457|Sphingomonadales	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_4064368_1	311402.Avi_5351	1.657e-101	339.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria,4B73C@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_4064368_0	311402.Avi_5350	1.586e-115	382.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,4BBR1@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_4064368_4	1463900.JOIX01000001_gene6610	4.165e-25	109.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_4064368_3	1410624.JNKK01000006_gene1860	1.223e-34	145.0	COG0457@1|root,COG0457@2|Bacteria,1TTVC@1239|Firmicutes,24ESN@186801|Clostridia,27J8V@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12,TPR_8
CMS3_k127_4064368_6	68170.KL590480_gene8644	4.49e-10	66.0	2DVEK@1|root,33VIT@2|Bacteria,2IG5Q@201174|Actinobacteria,4E50U@85010|Pseudonocardiales	201174|Actinobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
CMS3_k127_4064368_7	1210045.ALNP01000011_gene957	1.752e-05	57.0	COG3591@1|root,COG3591@2|Bacteria,2I4IQ@201174|Actinobacteria	201174|Actinobacteria	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_4064368_2	1382306.JNIM01000001_gene3705	6.206e-46	186.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2G8KB@200795|Chloroflexi	200795|Chloroflexi	K	NB-ARC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,NB-ARC,TPR_12
CMS3_k127_4084320_1	926569.ANT_27060	7.037e-45	167.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4084320_0	485913.Krac_8046	1.188e-55	222.0	COG3127@1|root,COG3127@2|Bacteria,2G7QS@200795|Chloroflexi	200795|Chloroflexi	Q	COGs COG3127 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_4085382_0	926550.CLDAP_40260	2.497e-29	132.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K13009,ko:K18814	-	-	-	-	ko00000,ko01000,ko01005,ko02000	9.B.67.1	-	-	Wzy_C
CMS3_k127_4093141_1	446470.Snas_3423	1.759e-05	56.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_4,Methyltransf_31
CMS3_k127_4093141_0	316274.Haur_1131	5.022e-43	168.0	COG0005@1|root,COG0005@2|Bacteria	2|Bacteria	F	purine-nucleoside phosphorylase activity	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_4097819_1	518766.Rmar_1923	4.155e-116	384.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS3_k127_4097819_2	926550.CLDAP_13010	1.495e-26	125.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,TPR_12,Trans_reg_C
CMS3_k127_4097819_5	743721.Psesu_0858	7.985e-07	54.0	2EU9B@1|root,33MRR@2|Bacteria,1PBGC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4097819_0	118161.KB235920_gene5993	3.803e-174	571.0	COG0464@1|root,COG0464@2|Bacteria,1G1YA@1117|Cyanobacteria,3VNFJ@52604|Pleurocapsales	1117|Cyanobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS3_k127_4097819_3	102129.Lepto7375DRAFT_2351	3.655e-24	113.0	COG0656@1|root,COG0656@2|Bacteria,1G6K0@1117|Cyanobacteria,1HFXE@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Ntox11
CMS3_k127_4097819_4	1313172.YM304_23190	1.132e-09	60.0	28RC2@1|root,32GK3@2|Bacteria,2HH3B@201174|Actinobacteria,4CP3D@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
CMS3_k127_4101974_1	926569.ANT_04720	1.64e-164	529.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
CMS3_k127_4101974_0	518766.Rmar_0522	3.348e-242	772.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1FJQW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	haloacid dehalogenase-like hydrolase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
CMS3_k127_4101974_10	926550.CLDAP_36860	5.635e-19	93.0	COG0517@1|root,COG0517@2|Bacteria,2G98X@200795|Chloroflexi	200795|Chloroflexi	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_4101974_6	448385.sce6011	2.143e-33	136.0	COG0529@1|root,COG0529@2|Bacteria,1QTVY@1224|Proteobacteria,434UM@68525|delta/epsilon subdivisions,2WZ5M@28221|Deltaproteobacteria,2Z1DN@29|Myxococcales	28221|Deltaproteobacteria	P	Adenylylsulfate kinase	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS3_k127_4101974_3	330214.NIDE3770	8.535e-88	304.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_4101974_4	926569.ANT_14300	9.458e-87	291.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4101974_5	926569.ANT_24720	4.043e-84	299.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_4101974_9	504728.K649_10820	1.424e-21	102.0	COG0517@1|root,COG0517@2|Bacteria,1WMQJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_4101974_12	29581.BW37_05311	3.03e-07	57.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,472DN@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_4101974_8	1089552.KI911559_gene828	3.463e-28	122.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,2JSUW@204441|Rhodospirillales	204441|Rhodospirillales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_4101974_11	309801.trd_A0139	7.842e-09	63.0	COG4243@1|root,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,27YHV@189775|Thermomicrobia	189775|Thermomicrobia	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
CMS3_k127_4101974_2	330214.NIDE1244	1.663e-93	319.0	COG0686@1|root,COG0686@2|Bacteria	2|Bacteria	E	alanine dehydrogenase activity	ald	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_4101974_7	443144.GM21_2862	1.279e-32	132.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
CMS3_k127_4102092_2	1192034.CAP_4731	5.224e-06	55.0	COG0457@1|root,COG5465@1|root,COG0457@2|Bacteria,COG5465@2|Bacteria,1NJM0@1224|Proteobacteria	1224|Proteobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
CMS3_k127_4102092_0	479434.Sthe_1210	1.552e-101	344.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27Y4V@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_4102092_1	568076.XP_007823115.1	7.055e-07	61.0	2E133@1|root,2S8FM@2759|Eukaryota,39QDU@33154|Opisthokonta,3Q6IW@4751|Fungi,3RPG5@4890|Ascomycota,21SG0@147550|Sordariomycetes,3TV0J@5125|Hypocreales,3G516@34397|Clavicipitaceae	4751|Fungi	G	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
CMS3_k127_4116594_3	670487.Ocepr_0162	2.317e-11	67.0	COG0220@1|root,COG0220@2|Bacteria,1WI0J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS3_k127_4116594_2	309801.trd_A0613	5.057e-112	376.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi,27YZB@189775|Thermomicrobia	189775|Thermomicrobia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_4116594_1	926550.CLDAP_03470	4.894e-115	378.0	COG0010@1|root,COG0010@2|Bacteria,2G5N5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_4116594_0	926550.CLDAP_11260	8.221e-153	495.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS3_k127_4116799_0	649638.Trad_1860	4.636e-213	671.0	COG0114@1|root,COG0114@2|Bacteria,1WJ9Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS3_k127_4116799_1	521011.Mpal_1345	1.378e-193	640.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
CMS3_k127_4116799_2	1254432.SCE1572_31930	5.255e-123	436.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,4389V@68525|delta/epsilon subdivisions,2X3J8@28221|Deltaproteobacteria,2YWAY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4117385_3	765420.OSCT_2007	1.437e-19	98.0	COG3012@1|root,COG3012@2|Bacteria,2GACR@200795|Chloroflexi,375EK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM SEC-C motif domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
CMS3_k127_4117385_2	1042877.GQS_03545	1.717e-20	101.0	COG1011@1|root,arCOG02291@2157|Archaea,2XWYR@28890|Euryarchaeota,243P8@183968|Thermococci	183968|Thermococci	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS3_k127_4117385_0	926550.CLDAP_09860	1.529e-100	338.0	COG2035@1|root,COG2035@2|Bacteria,2G6J1@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
CMS3_k127_4117385_1	926569.ANT_24460	3.27e-25	108.0	COG4250@1|root,COG4250@2|Bacteria	2|Bacteria	T	domain in sensory proteins (DUF2308)	-	-	-	-	-	-	-	-	-	-	-	-	DICT,GAF_2,STAS
CMS3_k127_4126257_3	765420.OSCT_1671	1.005e-28	123.0	COG0500@1|root,COG2226@2|Bacteria,2GB34@200795|Chloroflexi,3778K@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_4126257_2	869210.Marky_1415	8.827e-46	169.0	COG4319@1|root,COG4319@2|Bacteria,1WJSX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Calcium calmodulin dependent protein kinase II	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD
CMS3_k127_4126257_1	926550.CLDAP_00860	3.13e-93	313.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_4126257_0	926569.ANT_01750	6.394e-109	370.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
CMS3_k127_4129882_1	1131269.AQVV01000005_gene388	4.633e-56	209.0	COG3639@1|root,COG3639@2|Bacteria	2|Bacteria	P	organic phosphonate transmembrane transporter activity	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
CMS3_k127_4129882_3	589924.Ferp_0546	1.524e-32	132.0	COG0647@1|root,arCOG04221@2157|Archaea	2157|Archaea	G	sugar phosphatases of the HAD superfamily	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_4129882_2	926550.CLDAP_09500	3.206e-55	198.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_4129882_4	118005.AWNK01000004_gene1125	3.691e-22	106.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	AAA_25,P22_AR_N,Prim-Pol
CMS3_k127_4129882_0	926569.ANT_12750	5.71e-117	390.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
CMS3_k127_4153330_3	331869.BAL199_04764	2.116e-05	50.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,4BPQ6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the GcvT family	soxA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS3_k127_4153330_1	479434.Sthe_2157	1.787e-75	263.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_4153330_0	2002.JOEQ01000044_gene830	7.857e-293	906.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4ENHD@85012|Streptosporangiales	201174|Actinobacteria	E	GMC oxidoreductase	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_4153330_2	1260251.SPISAL_05360	5.554e-26	108.0	COG0665@1|root,COG0665@2|Bacteria,1R40G@1224|Proteobacteria,1SME5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_4156140_4	552398.HMPREF0866_02148	6.979e-12	68.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3WGTB@541000|Ruminococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
CMS3_k127_4156140_0	326427.Cagg_3777	0.0	1150.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi,376J5@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_4156140_3	177437.HRM2_08650	4.33e-110	366.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,42U95@68525|delta/epsilon subdivisions,2WQWB@28221|Deltaproteobacteria,2MNQA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphomethylpyrimidine kinase	-	-	2.7.1.11	ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS3_k127_4156140_1	177437.HRM2_08660	2.007e-261	818.0	COG1063@1|root,COG1063@2|Bacteria,1QA80@1224|Proteobacteria	1224|Proteobacteria	E	L-sorbose 1-phosphate reductase	-	-	-	ko:K19956	ko00051,map00051	-	R03234	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N
CMS3_k127_4156140_2	765913.ThidrDRAFT_0838	6.017e-175	566.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1WXBA@135613|Chromatiales	135613|Chromatiales	G	PEP-utilising enzyme, mobile	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
CMS3_k127_4163310_1	1089548.KI783301_gene1203	3.644e-54	214.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3WEHU@539002|Bacillales incertae sedis	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_4163310_0	926560.KE387023_gene3595	4.85e-69	259.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS3_k127_4166609_2	357808.RoseRS_0270	0.000786	45.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_4166609_1	33898.JRHJ01000089_gene2622	4.158e-22	100.0	COG1695@1|root,COG1695@2|Bacteria,2IQ70@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator padr family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS3_k127_4166609_0	883078.HMPREF9695_00766	4.654e-41	155.0	COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,2TU1P@28211|Alphaproteobacteria,3JQVJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	F420-0:Gamma-glutamyl ligase	cofE	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
CMS3_k127_4168056_1	43151.ADAC002712-PA	0.0001671	49.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa,3CSKJ@33213|Bilateria,41YHD@6656|Arthropoda,3SIXR@50557|Insecta,4519D@7147|Diptera,45CQ6@7148|Nematocera	33208|Metazoa	M	Pectinacetylesterase	NOTUM	GO:0000902,GO:0000904,GO:0003002,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008045,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009952,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0012505,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019538,GO:0019637,GO:0021532,GO:0021915,GO:0022008,GO:0023051,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030163,GO:0030178,GO:0030182,GO:0031175,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0035220,GO:0035222,GO:0035295,GO:0035601,GO:0036211,GO:0040011,GO:0042157,GO:0042159,GO:0042221,GO:0042330,GO:0042578,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046486,GO:0046488,GO:0048070,GO:0048073,GO:0048076,GO:0048190,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0052689,GO:0060429,GO:0060828,GO:0061564,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0090090,GO:0097485,GO:0098732,GO:0120036,GO:0120039,GO:1901135,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1990697,GO:1990699	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_4168056_0	622637.KE124774_gene2746	1.507e-21	106.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2TRQQ@28211|Alphaproteobacteria,36Z9I@31993|Methylocystaceae	28211|Alphaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_417122_0	1128421.JAGA01000002_gene1632	1.01e-30	139.0	COG1276@1|root,COG2010@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2010@2|Bacteria,COG2372@2|Bacteria,2NPS1@2323|unclassified Bacteria	2|Bacteria	P	Evidence 5 No homology to any previously reported sequences	ycnJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07156,ko:K07245,ko:K14166	-	-	-	-	ko00000,ko02000	9.B.62.1,9.B.62.2	-	-	CopC,CopD,Cytochrome_CBB3,YtkA
CMS3_k127_417122_1	1122931.AUAE01000027_gene2466	8.706e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia,22WD9@171551|Porphyromonadaceae	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8,TPR_9
CMS3_k127_4176847_0	316274.Haur_1492	2.991e-150	489.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,PKD
CMS3_k127_4180175_5	426117.M446_6162	1.212e-36	143.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,1JRJU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	MA20_36630	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CMS3_k127_4180175_9	457425.XNR_3213	1.502e-12	74.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2	ko:K03741,ko:K18701	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_4180175_1	511051.CSE_00390	4.721e-76	269.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS3_k127_4180175_2	338969.Rfer_0357	1.799e-64	224.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
CMS3_k127_4180175_6	330214.NIDE4035	3.143e-30	124.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_4180175_4	502025.Hoch_2836	3.291e-37	145.0	COG0789@1|root,COG0789@2|Bacteria,1PG5J@1224|Proteobacteria,438N8@68525|delta/epsilon subdivisions,2X9Z3@28221|Deltaproteobacteria,2Z2QY@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind
CMS3_k127_4180175_0	472759.Nhal_2157	1.154e-270	852.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1WVXM@135613|Chromatiales	135613|Chromatiales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_4180175_10	474922.ELA27115	5.498e-10	63.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NZ8C@4751|Fungi,3QR7F@4890|Ascomycota,2118T@147550|Sordariomycetes,1F3CB@1028384|Glomerellales	4751|Fungi	M	ankyrin repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,NACHT
CMS3_k127_4180175_7	1499967.BAYZ01000095_gene4191	1.635e-26	125.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_3,PAS_9,Response_reg,Sigma54_activat
CMS3_k127_4180175_3	1382306.JNIM01000001_gene1873	8.468e-58	221.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
CMS3_k127_4180175_8	326427.Cagg_2832	2.05e-19	102.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_4184836_2	258533.BN977_03376	1.436e-05	49.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,2352X@1762|Mycobacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4184836_1	211114.JOEF01000001_gene7240	1.736e-77	269.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4E068@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4184836_0	1380347.JNII01000006_gene1824	4.544e-147	490.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EX5G@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_4184836_3	591158.SSMG_03164	7.285e-05	51.0	2EKKQ@1|root,33EAI@2|Bacteria,2H1EK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4185434_1	926569.ANT_31200	3.23e-67	263.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_4185434_2	926550.CLDAP_29030	3.861e-25	112.0	COG4276@1|root,COG4276@2|Bacteria,2G9EV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4185434_0	926569.ANT_24470	1.19e-142	466.0	COG1233@1|root,COG1233@2|Bacteria,2G5U1@200795|Chloroflexi	200795|Chloroflexi	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_4195006_6	1089553.Tph_c04260	0.0009222	42.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,42FVU@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Iron-containing alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.202	ko:K00086,ko:K13954	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02377,R03119,R04880,R05233,R05234,R06917,R06927	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS3_k127_4195006_5	1313172.YM304_13170	8.891e-37	148.0	COG0518@1|root,COG0518@2|Bacteria,2ICUC@201174|Actinobacteria	201174|Actinobacteria	F	Peptidase C26	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS3_k127_4195006_2	935261.JAGL01000026_gene684	4.861e-135	446.0	COG5598@1|root,COG5598@2|Bacteria,1N18H@1224|Proteobacteria,2TRUE@28211|Alphaproteobacteria,43IVD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	mttB2	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS3_k127_4195006_4	1280952.HJA_06302	2.147e-85	293.0	COG2084@1|root,COG2084@2|Bacteria,1PHHI@1224|Proteobacteria,2V7VV@28211|Alphaproteobacteria,43ZV1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
CMS3_k127_4195006_1	986075.CathTA2_1639	9.656e-161	529.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,4HFIP@91061|Bacilli	1239|Firmicutes	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS3_k127_4195006_3	1385510.N781_15770	9.637e-130	424.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HF1Z@91061|Bacilli,2YBCE@289201|Pontibacillus	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS3_k127_4195006_0	926550.CLDAP_32740	1.005e-206	651.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_4218008_0	118168.MC7420_1927	4.883e-254	796.0	COG1132@1|root,COG1132@2|Bacteria,1G0EY@1117|Cyanobacteria,1H6XW@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4226661_1	1155718.KB891878_gene5473	6.528e-55	207.0	COG0815@1|root,COG0815@2|Bacteria,2GP8X@201174|Actinobacteria	201174|Actinobacteria	M	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_4226661_4	316274.Haur_2207	1.016e-05	52.0	COG1813@1|root,COG3903@1|root,COG1813@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12,Trans_reg_C
CMS3_k127_4226661_0	861299.J421_6088	2.446e-138	463.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_4226661_2	439235.Dalk_1865	1.465e-46	171.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,42QTZ@68525|delta/epsilon subdivisions,2WMV1@28221|Deltaproteobacteria,2MJRM@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_4226661_3	477641.MODMU_0965	4.722e-10	64.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4ETCD@85013|Frankiales	201174|Actinobacteria	S	Laminin G domain	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
CMS3_k127_4228551_0	502025.Hoch_5031	3.988e-265	847.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,438DH@68525|delta/epsilon subdivisions,2WXQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos
CMS3_k127_4235554_1	251221.35212543	1.283e-15	89.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
CMS3_k127_4235554_0	35754.JNYJ01000009_gene1953	7.097e-93	333.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2H3FC@201174|Actinobacteria	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS3_k127_4237968_2	1500897.JQNA01000002_gene3424	7.274e-121	394.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VZEK@28216|Betaproteobacteria,1K56M@119060|Burkholderiaceae	28216|Betaproteobacteria	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
CMS3_k127_4237968_8	316056.RPC_1154	0.0009541	50.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,2UC1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
CMS3_k127_4237968_7	1121378.KB899722_gene166	1.758e-08	65.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,Acyl-ACP_TE
CMS3_k127_4237968_6	1382306.JNIM01000001_gene1164	6.419e-27	117.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4237968_5	1379270.AUXF01000002_gene1144	2.592e-37	159.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
CMS3_k127_4237968_3	926550.CLDAP_19350	5.757e-119	387.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	iEC55989_1330.EC55989_1575,iECIAI1_1343.ECIAI1_1439,iECO111_1330.ECO111_1832,iECO26_1355.ECO26_2042,iECW_1372.ECW_m1571,iECs_1301.ECs2047,iEKO11_1354.EKO11_2376,iUMNK88_1353.UMNK88_1846,iWFL_1372.ECW_m1571,iZ_1308.Z2276,ic_1306.c1867	BPD_transp_1
CMS3_k127_4237968_4	395961.Cyan7425_3620	3.385e-116	382.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,3KIME@43988|Cyanothece	1117|Cyanobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
CMS3_k127_4237968_1	1894.JOER01000003_gene2827	9.899e-126	413.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
CMS3_k127_4237968_0	321332.CYB_0715	2.905e-162	515.0	COG1012@1|root,COG1012@2|Bacteria,1G2U1@1117|Cyanobacteria,1GYU6@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.8	ko:K00130	ko00260,ko01100,map00260,map01100	M00555	R02565,R02566	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4241126_0	517417.Cpar_1901	1.126e-163	524.0	COG0334@1|root,COG0334@2|Bacteria,1FE0H@1090|Chlorobi	1090|Chlorobi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_4241832_1	1237149.C900_02963	0.0009048	53.0	COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_8
CMS3_k127_4241832_0	45351.EDO43610	7.677e-180	572.0	COG0179@1|root,KOG2843@2759|Eukaryota,38HPV@33154|Opisthokonta,3BF5X@33208|Metazoa	33208|Metazoa	G	fumarylacetoacetase activity	FAH	GO:0003674,GO:0003824,GO:0004334,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
CMS3_k127_4246501_3	671143.DAMO_2439	2.839e-31	132.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_4246501_1	518766.Rmar_2000	3.535e-61	218.0	COG0778@1|root,COG0778@2|Bacteria,4NKRC@976|Bacteroidetes,1FJBU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_4246501_5	1094715.CM001373_gene483	4.458e-22	105.0	COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,1RPRS@1236|Gammaproteobacteria,1JDIB@118969|Legionellales	118969|Legionellales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS3_k127_4246501_0	357808.RoseRS_4327	3.01e-249	804.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi,375BC@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_8
CMS3_k127_4246501_2	1250232.JQNJ01000001_gene3553	2.659e-49	195.0	COG1680@1|root,COG1680@2|Bacteria,4NNBR@976|Bacteroidetes,1HZV1@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CMS3_k127_4246501_4	1380393.JHVP01000004_gene717	2.431e-27	123.0	COG2267@1|root,COG2267@2|Bacteria,2I6MZ@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4262036_0	234267.Acid_6996	0.0	1662.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,3Y415@57723|Acidobacteria	57723|Acidobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_4262036_1	926550.CLDAP_36880	5.616e-98	325.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_4264727_2	926550.CLDAP_32760	9.858e-108	370.0	COG0747@1|root,COG0747@2|Bacteria,2G8RA@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_4264727_1	1121946.AUAX01000017_gene4915	7.055e-198	673.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS3_k127_4264727_4	189753.AXAS01000084_gene6056	1.484e-25	126.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,Guanylate_cyc,SAM_1,Trans_reg_C
CMS3_k127_4264727_3	765420.OSCT_1798	1.348e-93	323.0	COG0443@1|root,COG0443@2|Bacteria,2GBRB@200795|Chloroflexi,3768Q@32061|Chloroflexia	32061|Chloroflexia	O	Hsp70 protein	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CMS3_k127_4264727_5	883114.HMPREF9709_00401	1.475e-13	83.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,22HB0@1570339|Peptoniphilaceae	186801|Clostridia	D	Peptidase, M23 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS3_k127_4264727_0	926550.CLDAP_23550	8.777e-227	711.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_4266795_2	435591.BDI_2976	4.627e-47	186.0	COG1397@1|root,COG1397@2|Bacteria,4NY3F@976|Bacteroidetes,2FZQI@200643|Bacteroidia,2313J@171551|Porphyromonadaceae	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4266795_1	439235.Dalk_1565	4.535e-58	214.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42P9B@68525|delta/epsilon subdivisions,2WMCP@28221|Deltaproteobacteria,2MMBX@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_4266795_0	1121377.KB906404_gene2866	1.793e-69	243.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	yobT	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4266795_3	1336243.JAEA01000011_gene3180	1.624e-39	156.0	COG1309@1|root,COG1309@2|Bacteria,1RKMF@1224|Proteobacteria,2UAP3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WHG
CMS3_k127_4266795_4	1336243.JAEA01000011_gene3180	6.871e-19	88.0	COG1309@1|root,COG1309@2|Bacteria,1RKMF@1224|Proteobacteria,2UAP3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	WHG
CMS3_k127_4274489_0	398767.Glov_2119	1.805e-18	102.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CMS3_k127_4274489_1	457425.XNR_2364	1.385e-10	76.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria	201174|Actinobacteria	T	Signal transduction protein with Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,HEAT_2,NACHT
CMS3_k127_4275017_0	316274.Haur_1891	3.295e-121	396.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi,37761@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4277532_2	1278073.MYSTI_07821	1.009e-09	69.0	COG0631@1|root,COG0631@2|Bacteria,1QTKZ@1224|Proteobacteria,43F3I@68525|delta/epsilon subdivisions,2X39B@28221|Deltaproteobacteria,2YUXJ@29|Myxococcales	28221|Deltaproteobacteria	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
CMS3_k127_4277532_0	530564.Psta_3548	2.713e-44	166.0	COG2062@1|root,COG2062@2|Bacteria,2J0N8@203682|Planctomycetes	203682|Planctomycetes	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS3_k127_4277532_1	1521187.JPIM01000050_gene3440	1.767e-34	155.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CHAT,NB-ARC,Pkinase,TPR_12,TPR_7,TPR_8
CMS3_k127_4278311_3	926550.CLDAP_30400	2.537e-92	329.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
CMS3_k127_4278311_5	521045.Kole_1810	2.385e-33	147.0	COG0470@1|root,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	-	-	-	ko:K07452,ko:K09384	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	TIR_2
CMS3_k127_4278311_2	349161.Dred_0025	1.328e-98	342.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia	186801|Clostridia	V	ATPase family associated with various cellular activities (AAA)	mcrB	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,EVE,Mrr_N
CMS3_k127_4278311_0	926560.KE387023_gene1701	1.954e-204	666.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_4278311_4	395961.Cyan7425_0749	2.225e-45	189.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS_8,PAS_9,Response_reg,SpoIIE
CMS3_k127_4278311_1	526227.Mesil_0256	1.019e-98	354.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
CMS3_k127_4279340_0	926569.ANT_01780	3.606e-197	625.0	COG1653@1|root,COG1653@2|Bacteria,2G5UT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117,ko:K17315	ko02010,map02010	M00196,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
CMS3_k127_4279340_1	926569.ANT_01790	8.467e-135	436.0	COG1175@1|root,COG1175@2|Bacteria,2G5W9@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
CMS3_k127_4279340_2	525904.Tter_0206	9.349e-105	347.0	COG0395@1|root,COG0395@2|Bacteria,2NQFE@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	gtsC	-	-	ko:K02026,ko:K17317	ko02010,map02010	M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
CMS3_k127_4279340_3	247490.KSU1_C0714	6.393e-78	273.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS3_k127_4286728_4	215803.DB30_5767	2.721e-10	74.0	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria,2Z267@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,VanY
CMS3_k127_4286728_2	1173027.Mic7113_3495	2e-13	84.0	COG3409@1|root,COG3409@2|Bacteria,1G5PD@1117|Cyanobacteria,1HB5T@1150|Oscillatoriales	1117|Cyanobacteria	M	peptidoglycan-binding domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
CMS3_k127_4286728_0	926550.CLDAP_40600	8.036e-164	524.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS3_k127_4286728_6	471852.Tcur_0284	2.927e-08	60.0	COG0515@1|root,COG0515@2|Bacteria,2GMUX@201174|Actinobacteria,4EHQK@85012|Streptosporangiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4286728_3	358681.BBR47_10770	3.58e-13	78.0	2DN69@1|root,32VSI@2|Bacteria	2|Bacteria	S	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
CMS3_k127_4286728_1	1121324.CLIT_2c03230	1.3e-55	208.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
CMS3_k127_429773_1	269799.Gmet_2821	4.101e-38	155.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,43UJ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NmrA-like family	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_429773_0	649831.L083_0267	6.311e-104	348.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4D9FN@85008|Micromonosporales	201174|Actinobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS3_k127_4299240_2	525904.Tter_1162	1.117e-32	133.0	COG2924@1|root,COG2924@2|Bacteria,2NRHF@2323|unclassified Bacteria	2|Bacteria	CO	Bacterial Fe(2+) trafficking	yggX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887	-	-	-	-	-	-	-	-	-	-	Iron_traffic
CMS3_k127_4299240_0	479434.Sthe_2607	9.579e-149	484.0	COG1032@1|root,COG1032@2|Bacteria,2G7MA@200795|Chloroflexi,27Y05@189775|Thermomicrobia	189775|Thermomicrobia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_4299240_1	395961.Cyan7425_0057	1.765e-91	316.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,3KIRB@43988|Cyanothece	1117|Cyanobacteria	CG	glycosyl transferase family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
CMS3_k127_4307603_1	1033739.CAEU01000027_gene3202	9.584e-49	195.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HDHF@91061|Bacilli	91061|Bacilli	GT	Phosphotransferase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS3_k127_4307603_0	485913.Krac_4241	5.104e-58	211.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_4307603_2	89187.ISM_00740	0.0006693	43.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_4309742_0	269797.Mbar_A0373	2.34e-122	404.0	COG0438@1|root,arCOG05174@2157|Archaea,2XX01@28890|Euryarchaeota,2N9IX@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_4309742_4	269797.Mbar_A0374	1.776e-30	134.0	COG0438@1|root,arCOG01411@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_transf_4,Glycos_transf_1
CMS3_k127_4309742_2	1382356.JQMP01000001_gene880	5.79e-55	203.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G84K@200795|Chloroflexi,27XSV@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS3_k127_4309742_3	479434.Sthe_2134	4.518e-50	184.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G84K@200795|Chloroflexi,27XSV@189775|Thermomicrobia	189775|Thermomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS3_k127_4309742_1	2325.TKV_c04220	1.257e-84	292.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,24BAN@186801|Clostridia,42F2W@68295|Thermoanaerobacterales	186801|Clostridia	C	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS3_k127_4317068_6	709986.Deima_0158	1.21e-15	89.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_4317068_4	596152.DesU5LDRAFT_0882	1.681e-57	223.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2M8ME@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_4317068_5	326427.Cagg_1541	1.679e-56	214.0	COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4317068_3	756067.MicvaDRAFT_2438	1.724e-60	222.0	COG0457@1|root,COG0457@2|Bacteria,1G9RM@1117|Cyanobacteria,1HF94@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4317068_0	595460.RRSWK_02658	5.68e-101	346.0	COG1134@1|root,COG1134@2|Bacteria,2IX6N@203682|Planctomycetes	203682|Planctomycetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_4317068_1	1499967.BAYZ01000014_gene6374	7.265e-93	312.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
CMS3_k127_4317068_2	926569.ANT_20060	5.972e-76	287.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,CBM_35,DUF1080,PKD
CMS3_k127_4317161_0	479431.Namu_2841	9.171e-18	98.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	BsuPI,LysM,PG_binding_1,Peptidase_M15_4
CMS3_k127_4317161_1	525368.HMPREF0591_3113	4.138e-06	57.0	COG3386@1|root,COG3386@2|Bacteria,2GNM1@201174|Actinobacteria,233K1@1762|Mycobacteriaceae	201174|Actinobacteria	G	SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS3_k127_4317270_1	926550.CLDAP_35610	9.769e-86	289.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	malF	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS3_k127_4317270_0	926550.CLDAP_35620	5.548e-170	551.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
CMS3_k127_4317270_3	316274.Haur_0593	2.34e-77	274.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_4317270_2	926569.ANT_11780	1.574e-83	309.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_4322597_1	861299.J421_4188	1.242e-71	245.0	COG0221@1|root,COG0221@2|Bacteria,1ZTH9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS3_k127_4322597_2	266834.SMc00397	3.374e-18	93.0	COG1247@1|root,COG1247@2|Bacteria,1QU6B@1224|Proteobacteria,2TW1F@28211|Alphaproteobacteria,4BEF9@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
CMS3_k127_4322597_0	318424.EU78_26750	1.981e-162	532.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,235H6@1762|Mycobacteriaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
CMS3_k127_4324453_2	313606.M23134_03548	7.059e-60	235.0	COG2911@1|root,COG4675@1|root,COG2911@2|Bacteria,COG4675@2|Bacteria,4P887@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4324453_0	449447.MAE_11540	6.193e-304	976.0	COG1413@1|root,COG1413@2|Bacteria,1G2TK@1117|Cyanobacteria	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4324453_1	497964.CfE428DRAFT_0631	5.505e-83	290.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_4332077_0	485913.Krac_4241	2.283e-86	294.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_4332077_1	1121015.N789_05975	4.796e-24	110.0	2DU7K@1|root,33P8K@2|Bacteria,1P4QZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4338258_0	1487953.JMKF01000075_gene3761	2.977e-108	366.0	COG2124@1|root,COG2124@2|Bacteria,1G3SX@1117|Cyanobacteria,1HE9Q@1150|Oscillatoriales	1117|Cyanobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_4338258_1	926569.ANT_14100	6.241e-53	202.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_4338258_2	1403313.AXBR01000015_gene2116	1.837e-41	177.0	COG2356@1|root,COG2374@1|root,COG4085@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,COG4085@2|Bacteria,1VKCH@1239|Firmicutes,4IS68@91061|Bacilli,1ZS2A@1386|Bacillus	91061|Bacilli	M	Fn3 associated	XK27_02140	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHB_HEX_C_1,Exo_endo_phos,Fn3_assoc,Gram_pos_anchor,LTD,SLH
CMS3_k127_434402_0	357808.RoseRS_1605	3.736e-131	432.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia	32061|Chloroflexia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_434402_1	479434.Sthe_3030	1.551e-78	276.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi,27Y4Y@189775|Thermomicrobia	189775|Thermomicrobia	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_4345940_6	1408473.JHXO01000015_gene1906	2.416e-14	83.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
CMS3_k127_4345940_7	1163408.UU9_12233	1.51e-13	82.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
CMS3_k127_4345940_4	313606.M23134_07925	6.54e-28	123.0	COG5492@1|root,COG5492@2|Bacteria,4NY38@976|Bacteroidetes	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4345940_1	926569.ANT_05540	5.012e-102	344.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS3_k127_4345940_3	234267.Acid_3202	2.342e-48	186.0	COG0596@1|root,COG0596@2|Bacteria,3Y89S@57723|Acidobacteria	57723|Acidobacteria	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4345940_5	311424.DhcVS_969	9.6e-16	80.0	COG0826@1|root,COG0826@2|Bacteria,2GAVB@200795|Chloroflexi,34DF3@301297|Dehalococcoidia	301297|Dehalococcoidia	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4345940_2	525368.HMPREF0591_5884	6.529e-71	262.0	COG0433@1|root,COG0561@1|root,COG0433@2|Bacteria,COG0561@2|Bacteria,2IDR0@201174|Actinobacteria,237AJ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,Hydrolase_3
CMS3_k127_4345940_0	1121374.KB891589_gene46	2.23e-132	432.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RN3S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_4345978_1	649638.Trad_0975	3.462e-93	313.0	COG0410@1|root,COG0410@2|Bacteria,1WJM5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS3_k127_4345978_0	869210.Marky_1015	1.099e-93	314.0	COG0411@1|root,COG0411@2|Bacteria,1WJG8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_4345978_2	296591.Bpro_3795	6.104e-58	221.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,4A9UK@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_4345978_3	762376.AXYL_03313	3.081e-57	207.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,3T2T8@506|Alcaligenaceae	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	livH1	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_4350211_0	483219.LILAB_26195	2.711e-297	947.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42M10@68525|delta/epsilon subdivisions,2X7TY@28221|Deltaproteobacteria,2YWPU@29|Myxococcales	28221|Deltaproteobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
CMS3_k127_4351078_1	472175.EL18_01955	1.309e-50	203.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2U0ME@28211|Alphaproteobacteria,43QDB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	N	Integrin alpha (beta-propellor repeats).	exsH	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Glyco_hydro_16,HemolysinCabind,W_rich_C
CMS3_k127_4351078_0	314271.RB2654_10713	4.921e-65	248.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_4351078_3	938709.AUSH02000051_gene200	8.037e-06	60.0	COG1404@1|root,COG3291@1|root,COG3405@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SLH,SdrD_B
CMS3_k127_4351078_2	1122223.KB890697_gene993	2.693e-41	176.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1WM4S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_4353310_0	383372.Rcas_3701	9.581e-91	325.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS3_k127_4357833_7	391625.PPSIR1_41429	9.406e-31	132.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,42UVY@68525|delta/epsilon subdivisions,2WR44@28221|Deltaproteobacteria,2YVAT@29|Myxococcales	28221|Deltaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS3_k127_4357833_9	326427.Cagg_1471	2.886e-16	87.0	2FF2N@1|root,3470Y@2|Bacteria,2G9SF@200795|Chloroflexi,37769@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4357833_2	926569.ANT_27790	3.411e-71	254.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_4357833_1	926569.ANT_30570	5.488e-108	361.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
CMS3_k127_4357833_0	880073.Calab_2597	6.526e-166	534.0	COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS3_k127_4357833_4	326427.Cagg_2692	4.77e-65	231.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi,375AH@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS3_k127_4357833_3	926569.ANT_24820	3.046e-66	241.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS3_k127_4357833_6	357808.RoseRS_3747	8.794e-43	165.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_4357833_8	1242864.D187_001667	8.034e-24	104.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
CMS3_k127_435822_1	316274.Haur_1206	2.867e-14	76.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_435822_0	479434.Sthe_0598	9.482e-76	269.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_4359474_1	1131269.AQVV01000028_gene29	1.164e-42	168.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_4359474_2	1123023.JIAI01000022_gene2321	6.003e-06	57.0	COG0515@1|root,COG1073@1|root,COG0515@2|Bacteria,COG1073@2|Bacteria,2IKPQ@201174|Actinobacteria,4E6JV@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
CMS3_k127_4359474_0	1191523.MROS_0930	2.03e-137	452.0	COG0787@1|root,COG0787@2|Bacteria	2|Bacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS3_k127_4365779_2	1449976.KALB_4606	1.763e-13	85.0	COG5276@1|root,COG5276@2|Bacteria,2I3D6@201174|Actinobacteria,4EDSJ@85010|Pseudonocardiales	201174|Actinobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS3_k127_4365779_4	118166.JH976537_gene2953	0.0001314	55.0	COG0265@1|root,COG0265@2|Bacteria,1G0XN@1117|Cyanobacteria,1H8PC@1150|Oscillatoriales	1117|Cyanobacteria	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PPC,Trypsin_2
CMS3_k127_4365779_3	402777.KB235898_gene5348	2.782e-09	71.0	COG0265@1|root,COG0265@2|Bacteria,1G0XN@1117|Cyanobacteria,1H8PC@1150|Oscillatoriales	1117|Cyanobacteria	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PPC,Trypsin_2
CMS3_k127_4365779_0	765420.OSCT_3186	2.214e-81	297.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS3_k127_4365779_1	526225.Gobs_1160	9.048e-71	256.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,TIR_2,WD40
CMS3_k127_436868_2	1541065.JRFE01000025_gene1987	1.369e-27	114.0	COG4456@1|root,COG4456@2|Bacteria,1G95Y@1117|Cyanobacteria,3VN3Y@52604|Pleurocapsales	1117|Cyanobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	vapB	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
CMS3_k127_436868_1	269796.Rru_A1945	6.046e-33	139.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2TUR9@28211|Alphaproteobacteria,2JSEA@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_436868_0	926569.ANT_12970	4.646e-42	158.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS3_k127_4370021_2	697284.ERIC2_c10030	3.763e-45	169.0	COG1250@1|root,COG1250@2|Bacteria,1TSZI@1239|Firmicutes,4HBK3@91061|Bacilli,26UKH@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_4370021_4	502025.Hoch_0529	1.022e-13	73.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
CMS3_k127_4370021_1	383372.Rcas_2811	1.854e-98	363.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1,3.2.1.50	ko:K01205,ko:K07004,ko:K12132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko04147	-	-	-	DUF3662,DUF916,FHA,NAGLU,NAGLU_C,NAGLU_N,Yop-YscD_cpl
CMS3_k127_4370021_3	1121405.dsmv_2638	9.65e-14	79.0	COG1073@1|root,COG1073@2|Bacteria,1R1IT@1224|Proteobacteria,432AP@68525|delta/epsilon subdivisions,2WY9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4370021_0	926569.ANT_10660	1.931e-120	389.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS3_k127_437747_3	1279038.KB907342_gene2577	1.284e-15	86.0	COG0457@1|root,COG0664@1|root,COG0457@2|Bacteria,COG0664@2|Bacteria,1R4NF@1224|Proteobacteria,2TREU@28211|Alphaproteobacteria,2JRMY@204441|Rhodospirillales	204441|Rhodospirillales	K	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,cNMP_binding
CMS3_k127_437747_2	1122132.AQYH01000010_gene4009	2.598e-24	115.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_437747_0	765420.OSCT_2998	7.583e-87	303.0	COG1251@1|root,COG1251@2|Bacteria,2G6YZ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pyr_redox_2
CMS3_k127_437747_4	1124780.ANNU01000008_gene2732	6.611e-14	76.0	COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia	976|Bacteroidetes	C	4Fe-4S dicluster domain	yccM_2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7,Fer4_9
CMS3_k127_437747_1	765420.OSCT_2999	4.939e-42	164.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
CMS3_k127_4377623_0	926569.ANT_10860	0.0	1688.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS3_k127_4378832_4	465541.ATCJ01000005_gene6201	2.779e-36	147.0	2CKQ5@1|root,32SCT@2|Bacteria,2GNYR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4378832_1	331869.BAL199_12946	2.329e-82	283.0	COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,2TUQN@28211|Alphaproteobacteria,4BSA5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	ko:K10678	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CMS3_k127_4378832_0	180281.CPCC7001_2444	7.15e-162	514.0	COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS3_k127_4378832_3	1536770.R50345_17540	1.71e-44	167.0	COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS3_k127_4378832_2	1173264.KI913949_gene1876	3.031e-48	176.0	COG0346@1|root,COG0346@2|Bacteria,1GB6Q@1117|Cyanobacteria	1117|Cyanobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4378832_6	357808.RoseRS_1405	6.35e-14	79.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS3_k127_4378832_5	36630.CADNFIAP00000353	6.829e-31	138.0	KOG0266@1|root,KOG0271@1|root,KOG0266@2759|Eukaryota,KOG0271@2759|Eukaryota,38B6D@33154|Opisthokonta,3P11N@4751|Fungi,3RM59@4890|Ascomycota,20T5A@147545|Eurotiomycetes	4751|Fungi	S	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,PNP_UDP_1,WD40
CMS3_k127_4382239_0	926569.ANT_08920	2.912e-82	284.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_4382867_4	357808.RoseRS_2519	8.189e-58	214.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_4382867_6	926569.ANT_21000	1.336e-37	147.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
CMS3_k127_4382867_9	1128421.JAGA01000003_gene3580	3.04e-15	80.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	amcY	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
CMS3_k127_4382867_8	644966.Tmar_1104	9.711e-22	100.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
CMS3_k127_4382867_7	926569.ANT_04330	7.668e-31	131.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS3_k127_4382867_1	693661.Arcve_1981	3.101e-67	256.0	COG0747@1|root,arCOG01534@2157|Archaea,2XTPJ@28890|Euryarchaeota,246Q1@183980|Archaeoglobi	183980|Archaeoglobi	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_4382867_10	547045.NEISICOT_01543	1.643e-14	88.0	COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,2VMB5@28216|Betaproteobacteria,2KPJU@206351|Neisseriales	206351|Neisseriales	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS3_k127_4382867_5	552811.Dehly_1323	7.352e-45	171.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,34D3P@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS3_k127_4382867_2	867845.KI911784_gene2784	2.224e-61	217.0	COG2191@1|root,COG2191@2|Bacteria,2G7H2@200795|Chloroflexi,376Q2@32061|Chloroflexia	32061|Chloroflexia	C	PFAM formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
CMS3_k127_4382867_3	1173028.ANKO01000065_gene5587	7.695e-61	217.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1H8MW@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS3_k127_4382867_0	926550.CLDAP_13030	1.377e-111	376.0	COG0128@1|root,COG0128@2|Bacteria,2G5TT@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS3_k127_4383411_8	1197906.CAJQ02000047_gene4077	1.338e-14	74.0	COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4383411_3	573413.Spirs_4162	3.349e-53	192.0	COG0346@1|root,COG0346@2|Bacteria,2JA7S@203691|Spirochaetes	203691|Spirochaetes	C	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4383411_9	208444.JNYY01000008_gene8675	2.489e-13	71.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria,4E8XP@85010|Pseudonocardiales	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
CMS3_k127_4383411_6	267608.RSp1117	2.179e-19	93.0	2AAWD@1|root,3109H@2|Bacteria,1N31N@1224|Proteobacteria	1224|Proteobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
CMS3_k127_4383411_4	710696.Intca_0345	1.079e-49	184.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_4383411_5	1216967.L100_13949	1.85e-19	95.0	COG0454@1|root,COG0456@2|Bacteria,4NUQU@976|Bacteroidetes,1I53H@117743|Flavobacteriia,34RR0@308865|Elizabethkingia	976|Bacteroidetes	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_4383411_10	235909.GK2874	5.242e-07	61.0	COG2267@1|root,COG2267@2|Bacteria,1W2QR@1239|Firmicutes,4I0G2@91061|Bacilli,1WEWU@129337|Geobacillus	91061|Bacilli	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4383411_0	880073.Calab_0989	8.167e-157	501.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS3_k127_4383411_7	1408452.JAGZ01000001_gene3477	9.338e-16	85.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,232ZS@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_4383411_1	439235.Dalk_2094	1.37e-104	364.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria,2MPUY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS3_k127_4383411_2	1499967.BAYZ01000052_gene4665	6.885e-67	244.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_4383980_1	323261.Noc_1864	5.391e-131	447.0	COG3299@1|root,COG3299@2|Bacteria,1MWKI@1224|Proteobacteria,1S0AE@1236|Gammaproteobacteria,1X0R0@135613|Chromatiales	135613|Chromatiales	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CMS3_k127_4383980_0	323261.Noc_1865	1.905e-230	754.0	COG3299@1|root,COG3299@2|Bacteria,1PF9H@1224|Proteobacteria,1SXC0@1236|Gammaproteobacteria,1X1IG@135613|Chromatiales	135613|Chromatiales	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
CMS3_k127_4383980_2	1122622.ATWJ01000007_gene1732	2.179e-42	158.0	COG3628@1|root,COG3628@2|Bacteria,2IFJ6@201174|Actinobacteria,4FI0Z@85021|Intrasporangiaceae	201174|Actinobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K06903	-	-	-	-	ko00000	-	-	-	GPW_gp25
CMS3_k127_4385053_0	1121382.JQKG01000001_gene2263	8.836e-256	809.0	COG1501@1|root,COG1501@2|Bacteria,1WJ3Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Gal_mutarotas_2,Glyco_hydro_31
CMS3_k127_4388677_2	926569.ANT_11650	2.583e-109	365.0	COG1239@1|root,COG1239@2|Bacteria,2G832@200795|Chloroflexi	200795|Chloroflexi	H	SMART AAA ATPase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
CMS3_k127_4388677_6	479434.Sthe_0091	9.971e-44	165.0	COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_4388677_4	1128421.JAGA01000002_gene1655	6.836e-83	290.0	COG0438@1|root,COG0438@2|Bacteria,2NR3F@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_4388677_7	926569.ANT_11660	1.045e-33	135.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CMS3_k127_4388677_5	926550.CLDAP_33690	2.278e-69	254.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_4388677_0	383372.Rcas_4267	1.688e-151	483.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,374WM@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_4388677_1	926569.ANT_20510	1.741e-123	405.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
CMS3_k127_4388677_3	926550.CLDAP_15940	3.474e-88	301.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_4389881_2	1453505.JASY01000022_gene204	0.0005734	46.0	2EQWH@1|root,33IGA@2|Bacteria,4NXMB@976|Bacteroidetes,1I6QT@117743|Flavobacteriia,2NXCT@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF4236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
CMS3_k127_4389881_1	298654.FraEuI1c_6746	3.096e-07	63.0	COG0723@1|root,COG0723@2|Bacteria,2I2RI@201174|Actinobacteria,4EUMX@85013|Frankiales	201174|Actinobacteria	C	plastoquinol--plastocyanin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4389881_0	1313421.JHBV01000016_gene5604	2.872e-44	170.0	2DHAX@1|root,32U8Z@2|Bacteria	2|Bacteria	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
CMS3_k127_4394453_0	338966.Ppro_3550	1.39e-231	727.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,43T6U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS3_k127_4394453_1	1121406.JAEX01000021_gene1440	4.547e-61	215.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2M8AC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS3_k127_4397367_2	595460.RRSWK_00040	1.801e-157	510.0	COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS3_k127_4397367_1	63737.Npun_F1435	2.598e-269	843.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,1HS4D@1161|Nostocales	1117|Cyanobacteria	G	glycogen debranching	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
CMS3_k127_4397367_4	765420.OSCT_1383	3.843e-39	155.0	COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_4397367_0	671143.DAMO_0621	0.0	1208.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
CMS3_k127_4397367_5	326427.Cagg_0725	7.365e-39	154.0	2EDBT@1|root,33781@2|Bacteria,2G8Y5@200795|Chloroflexi,376V2@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4397367_3	1382306.JNIM01000001_gene2484	1.494e-91	334.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G6X4@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
CMS3_k127_4397367_9	1449058.JQKT01000009_gene104	5.282e-06	59.0	COG1404@1|root,COG1404@2|Bacteria,2GNIX@201174|Actinobacteria	201174|Actinobacteria	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_4397367_7	1122609.AUGT01000023_gene472	2.487e-36	148.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria,4DU7T@85009|Propionibacteriales	201174|Actinobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
CMS3_k127_4397367_6	1121930.AQXG01000001_gene1271	2.092e-37	148.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_4397367_8	46429.BV95_03440	1.468e-20	94.0	COG2085@1|root,COG2085@2|Bacteria,1MXS0@1224|Proteobacteria,2TS1W@28211|Alphaproteobacteria,2K27G@204457|Sphingomonadales	204457|Sphingomonadales	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
CMS3_k127_4398618_2	1380367.JIBC01000008_gene1260	9.704e-21	104.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,3ZZFY@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_4398618_1	1449069.JMLO01000034_gene106	1.093e-41	159.0	COG1695@1|root,COG1695@2|Bacteria,2IHC2@201174|Actinobacteria,4G3NC@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS3_k127_4398618_0	1282361.ABAC402_16270	5.658e-79	269.0	COG4832@1|root,COG4832@2|Bacteria,1RBGY@1224|Proteobacteria,2U72S@28211|Alphaproteobacteria,2KJ62@204458|Caulobacterales	204458|Caulobacterales	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
CMS3_k127_4399897_0	525904.Tter_2199	1.722e-97	326.0	COG2227@1|root,COG2227@2|Bacteria,2NRF7@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
CMS3_k127_4400916_0	357808.RoseRS_2738	1.164e-83	282.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi,3777M@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4400916_1	326427.Cagg_0604	2.492e-43	180.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GABQ@200795|Chloroflexi,3751C@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HATPase_c,HisKA,PAS_4
CMS3_k127_4405776_1	1155718.KB891899_gene1824	1.379e-41	159.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	ko:K16033	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09851	RC01363	ko00000,ko00001	-	-	-	Trp_halogenase
CMS3_k127_4405776_2	713587.THITH_04240	1.124e-26	119.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,TPMT
CMS3_k127_4405776_4	1122963.AUHB01000023_gene79	1.163e-13	79.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TPMT
CMS3_k127_4405776_6	99598.Cal7507_5044	1.991e-10	64.0	COG0236@1|root,COG0236@2|Bacteria,1GEI4@1117|Cyanobacteria,1HTDU@1161|Nostocales	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	-
CMS3_k127_4405776_5	1173025.GEI7407_0523	1.989e-11	73.0	COG0500@1|root,COG0500@2|Bacteria,1G56P@1117|Cyanobacteria,1HAXF@1150|Oscillatoriales	1117|Cyanobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
CMS3_k127_4405776_3	469382.Hbor_16090	1.328e-23	109.0	arCOG09395@1|root,arCOG09395@2157|Archaea,2XTUR@28890|Euryarchaeota,23S6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS3_k127_4405776_7	869210.Marky_0994	1.529e-07	59.0	COG2128@1|root,COG2128@2|Bacteria,1WJ8T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS3_k127_4405776_0	56107.Cylst_6224	6.183e-113	375.0	COG1020@1|root,COG1020@2|Bacteria,1GQ70@1117|Cyanobacteria,1HRJ2@1161|Nostocales	1117|Cyanobacteria	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS3_k127_4408588_0	1394178.AWOO02000019_gene7528	5.645e-110	377.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EGKM@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
CMS3_k127_4409602_1	1337093.MBE-LCI_3671	9.543e-19	91.0	COG1522@1|root,COG1522@2|Bacteria,1RI7R@1224|Proteobacteria,2U9CC@28211|Alphaproteobacteria,2P8UN@245186|Loktanella	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	aldR	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
CMS3_k127_4409602_0	316274.Haur_3713	2.09e-72	260.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3759M@32061|Chloroflexia	32061|Chloroflexia	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_4418442_0	926569.ANT_22700	1.401e-243	766.0	COG1132@1|root,COG1132@2|Bacteria,2G7KA@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4418442_1	383372.Rcas_3701	6.994e-116	411.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS3_k127_4421176_0	765420.OSCT_2101	3.179e-196	627.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_4421176_1	1444309.JAQG01000011_gene2244	4.753e-112	381.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,26T63@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
CMS3_k127_4421176_2	1206733.BAGC01000035_gene3639	7.258e-77	263.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4FYMF@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4425585_2	401053.AciPR4_1543	1.423e-59	213.0	COG2258@1|root,COG2258@2|Bacteria,3Y8MZ@57723|Acidobacteria,2JNIF@204432|Acidobacteriia	204432|Acidobacteriia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS3_k127_4425585_1	926560.KE387023_gene2648	1.455e-99	334.0	COG1893@1|root,COG1893@2|Bacteria,1WMJG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS3_k127_4425585_0	1123073.KB899243_gene698	6.844e-192	608.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQRJ@1236|Gammaproteobacteria,1X83S@135614|Xanthomonadales	135614|Xanthomonadales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS3_k127_4425585_3	1385935.N836_34705	1.141e-44	171.0	COG0703@1|root,COG0703@2|Bacteria,1G7N0@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4425585_4	1957.JODX01000006_gene3772	3.683e-13	70.0	2CKQ5@1|root,32SCT@2|Bacteria,2GNYR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4426980_3	926569.ANT_31290	0.00025	53.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
CMS3_k127_4426980_2	926550.CLDAP_36010	1.481e-24	117.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.5.1.28	ko:K01448,ko:K07448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036	-	-	-	Muraidase,SH3_3,SLH
CMS3_k127_4426980_0	935261.JAGL01000032_gene3819	4.413e-106	359.0	COG2132@1|root,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria,43JBX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	nitrite reductase, copper-containing	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C
CMS3_k127_4426980_1	326427.Cagg_2053	4.753e-53	192.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi,37744@32061|Chloroflexia	32061|Chloroflexia	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_4433272_4	1500257.JQNM01000019_gene2757	3.263e-52	198.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
CMS3_k127_4433272_1	1499967.BAYZ01000036_gene2419	4.952e-174	548.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
CMS3_k127_4433272_0	1499967.BAYZ01000036_gene2418	0.0	1189.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_4433272_7	1304885.AUEY01000002_gene413	2.544e-20	96.0	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PF2@68525|delta/epsilon subdivisions,2WIJI@28221|Deltaproteobacteria,2MIE4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,SBP_bac_3
CMS3_k127_4433272_5	316274.Haur_2801	5.306e-52	200.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_4433272_2	1128421.JAGA01000002_gene1281	1.033e-81	287.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_4433272_10	1218103.CIN01S_07_01890	0.0002033	46.0	2E826@1|root,310SY@2|Bacteria,4PFEP@976|Bacteroidetes,1IHDT@117743|Flavobacteriia,3ZU19@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4433272_9	1232410.KI421421_gene3359	5.244e-07	56.0	COG4980@1|root,COG4980@2|Bacteria,1NEPD@1224|Proteobacteria,42WE2@68525|delta/epsilon subdivisions,2WRDT@28221|Deltaproteobacteria,43SRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS3_k127_4433272_8	479434.Sthe_2550	1.204e-17	89.0	COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia	189775|Thermomicrobia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4433272_6	1128421.JAGA01000002_gene949	2.312e-29	119.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS3_k127_4433272_3	886293.Sinac_4302	1.182e-68	241.0	COG3266@1|root,COG4655@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4655@2|Bacteria,COG4932@2|Bacteria,2IZVN@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function (DUF3494)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF3494
CMS3_k127_4445988_5	926550.CLDAP_04380	1.183e-46	182.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
CMS3_k127_4445988_0	479434.Sthe_1003	3.059e-183	582.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS3_k127_4445988_1	263358.VAB18032_27736	7.686e-150	495.0	COG5276@1|root,COG5276@2|Bacteria,2IAAZ@201174|Actinobacteria,4DBJS@85008|Micromonosporales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,P_proprotein
CMS3_k127_4445988_3	926569.ANT_22590	1.33e-101	341.0	COG2515@1|root,COG2515@2|Bacteria,2G6PX@200795|Chloroflexi	200795|Chloroflexi	E	1-aminocyclopropane-1-carboxylate deaminase	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
CMS3_k127_4445988_4	926550.CLDAP_12370	6.697e-81	293.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4445988_2	926550.CLDAP_12360	5.385e-125	416.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350,ko:K21000	ko00460,ko00500,ko00940,ko01100,ko01110,ko02025,map00460,map00500,map00940,map01100,map01110,map02025	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH39	-	Cellulase,Glyco_hydro_1
CMS3_k127_4446017_1	316274.Haur_1472	6.319e-33	145.0	COG5617@1|root,COG5617@2|Bacteria,2GAHU@200795|Chloroflexi,3767W@32061|Chloroflexia	32061|Chloroflexia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4446017_2	1173029.JH980292_gene2124	2.06e-29	134.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT,PMT_2
CMS3_k127_4448388_1	1521187.JPIM01000006_gene1717	3.468e-61	215.0	COG4586@1|root,COG4586@2|Bacteria,2G88B@200795|Chloroflexi,376NY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4448388_0	383372.Rcas_2072	1.567e-79	279.0	COG1057@1|root,COG1057@2|Bacteria,2GASF@200795|Chloroflexi,3777U@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4449967_0	945713.IALB_1293	1.56e-165	534.0	COG1523@1|root,COG4935@1|root,COG1523@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PUD,Reprolysin_4
CMS3_k127_4449967_2	1173020.Cha6605_4223	1.526e-05	54.0	COG3881@1|root,COG3881@2|Bacteria,1G23A@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
CMS3_k127_4449967_1	926550.CLDAP_29150	6.149e-142	460.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4453083_0	1123253.AUBD01000010_gene2213	2.408e-27	126.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1X4K0@135614|Xanthomonadales	135614|Xanthomonadales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS3_k127_4456603_1	926550.CLDAP_10440	3.958e-22	102.0	COG0438@1|root,COG0438@2|Bacteria,2G6KX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS3_k127_4456603_0	479434.Sthe_0849	1.238e-54	207.0	COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS3_k127_4460784_0	1379698.RBG1_1C00001G0194	2.326e-138	454.0	COG3211@1|root,COG3540@1|root,COG3211@2|Bacteria,COG3540@2|Bacteria,2NS16@2323|unclassified Bacteria	2|Bacteria	P	PhoD-like phosphatase	phoX	-	3.1.3.1	ko:K01113,ko:K07093	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF839
CMS3_k127_4460784_1	1499967.BAYZ01000009_gene5348	6.297e-76	260.0	COG1428@1|root,COG1428@2|Bacteria,2NR23@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
CMS3_k127_4460784_2	926550.CLDAP_28500	9.022e-50	183.0	COG1905@1|root,COG1905@2|Bacteria,2G6Q5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	hoxE	-	1.6.5.3	ko:K00334,ko:K05586	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS3_k127_4468739_0	926550.CLDAP_23540	5.523e-260	822.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS3_k127_4474881_1	929712.KI912613_gene435	9.412e-15	87.0	COG1807@1|root,COG1807@2|Bacteria,2GVIK@201174|Actinobacteria,4CQCI@84995|Rubrobacteria	84995|Rubrobacteria	M	Predicted membrane protein (DUF2142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS3_k127_4474881_0	886293.Sinac_7280	3.075e-78	271.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4475884_0	1232410.KI421413_gene842	1.721e-107	360.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS3_k127_4475884_2	926569.ANT_20480	1.005e-16	86.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4475884_1	395493.BegalDRAFT_2584	1.16e-49	186.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,4601S@72273|Thiotrichales	72273|Thiotrichales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS3_k127_4476076_1	926569.ANT_05390	6.849e-70	244.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS3_k127_4476076_0	2325.TKV_c05160	1.522e-116	385.0	COG1239@1|root,COG1239@2|Bacteria,1UHYK@1239|Firmicutes,24BJ0@186801|Clostridia,42ESQ@68295|Thermoanaerobacterales	186801|Clostridia	H	Magnesium chelatase, subunit ChlI	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
CMS3_k127_4477634_2	1121930.AQXG01000005_gene597	3.52e-82	276.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1IUKS@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_4477634_0	926550.CLDAP_37050	2.209e-118	388.0	COG0667@1|root,COG0667@2|Bacteria,2G631@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_4477634_8	324602.Caur_2608	1.398e-35	153.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi,375IB@32061|Chloroflexia	32061|Chloroflexia	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
CMS3_k127_4477634_4	926569.ANT_12990	6.361e-78	279.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
CMS3_k127_4477634_11	996637.SGM_6132	3.879e-15	82.0	COG1051@1|root,COG1051@2|Bacteria,2IIJJ@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_4477634_10	926560.KE387027_gene895	9.564e-23	102.0	COG1983@1|root,COG1983@2|Bacteria,1WKSH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
CMS3_k127_4477634_3	1521187.JPIM01000052_gene3535	2.093e-79	286.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi,375B4@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_4477634_1	926569.ANT_28720	1.141e-90	304.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_4477634_9	926569.ANT_23660	4.236e-25	118.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS3_k127_4477634_7	926550.CLDAP_37980	2.289e-39	156.0	COG0500@1|root,COG1819@1|root,COG1819@2|Bacteria,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_4477634_6	1128421.JAGA01000003_gene2897	7.973e-41	160.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_4477634_5	448385.sce3073	6.087e-61	224.0	COG4402@1|root,COG4402@2|Bacteria,1QA5C@1224|Proteobacteria,434UU@68525|delta/epsilon subdivisions,2WZ5W@28221|Deltaproteobacteria,2Z1E4@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CMS3_k127_4479463_1	926569.ANT_09990	1.149e-61	214.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi	200795|Chloroflexi	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS3_k127_4479463_2	926569.ANT_10000	5.316e-54	193.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS3_k127_4479463_0	243231.GSU2860	5.132e-288	899.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_4479463_3	132113.XP_003494244.1	0.0001857	44.0	COG0050@1|root,KOG0460@2759|Eukaryota,38BHM@33154|Opisthokonta,3BE5J@33208|Metazoa,3CUKG@33213|Bilateria,41VN7@6656|Arthropoda,3SFX6@50557|Insecta,46FE1@7399|Hymenoptera	33208|Metazoa	J	Elongation factor	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS3_k127_4487095_1	2903.EOD19049	9.774e-06	58.0	KOG3710@1|root,KOG3710@2759|Eukaryota	2759|Eukaryota	Q	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	-	-	1.14.11.29	ko:K09592	ko04066,ko05200,ko05211,map04066,map05200,map05211	-	-	-	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
CMS3_k127_4487095_0	504472.Slin_0892	5.309e-13	82.0	28KQG@1|root,2ZA89@2|Bacteria,4NKET@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4
CMS3_k127_4488070_0	926560.KE387023_gene2413	8.685e-54	193.0	COG2936@1|root,COG2936@2|Bacteria,1WN5B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_4488070_2	471870.BACINT_01939	8.055e-05	49.0	2C6H2@1|root,33K98@2|Bacteria,4P7EH@976|Bacteroidetes,2FS4S@200643|Bacteroidia,4AQTD@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4488070_1	1519464.HY22_09115	1.376e-28	120.0	2EE5F@1|root,33800@2|Bacteria,1FFN1@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4497819_13	765420.OSCT_0762	4.108e-14	77.0	COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS3_k127_4497819_5	1128421.JAGA01000002_gene351	1.694e-98	329.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS3_k127_4497819_7	1128421.JAGA01000002_gene412	2.459e-81	287.0	COG0534@1|root,COG0534@2|Bacteria,2NPFE@2323|unclassified Bacteria	2|Bacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
CMS3_k127_4497819_10	649638.Trad_0407	1.072e-53	198.0	COG0491@1|root,COG0491@2|Bacteria,1WIMP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4497819_6	485913.Krac_5027	8.308e-96	346.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_4497819_12	926569.ANT_17240	3.033e-25	121.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
CMS3_k127_4497819_8	479434.Sthe_3414	2.501e-81	281.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,NTP_transf_2,UPF0158
CMS3_k127_4497819_0	479434.Sthe_3413	3.72e-228	718.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4497819_11	383372.Rcas_1611	1.675e-43	166.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
CMS3_k127_4497819_9	383372.Rcas_1610	4.577e-56	207.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS3_k127_4497819_1	479434.Sthe_3412	5.183e-170	546.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_4497819_4	861299.J421_0843	1.277e-101	342.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqC	-	1.3.3.11	ko:K06137,ko:K06138	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM,TENA_THI-4
CMS3_k127_4497819_3	926560.KE387028_gene161	3.183e-124	409.0	COG0428@1|root,COG0428@2|Bacteria,1WM75@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4497819_2	869210.Marky_0543	3.503e-140	455.0	COG2132@1|root,COG2132@2|Bacteria,1WJQI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_4512675_0	1237149.C900_04789	1.087e-182	583.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_4512675_1	1128421.JAGA01000002_gene1768	7.703e-125	412.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS3_k127_4512675_3	1382356.JQMP01000004_gene626	3.515e-28	115.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi,27YG7@189775|Thermomicrobia	189775|Thermomicrobia	S	Stage V sporulation protein S (SpoVS)	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
CMS3_k127_4512675_2	926569.ANT_19080	5.097e-114	378.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS3_k127_4512709_2	316274.Haur_0854	2.073e-11	72.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
CMS3_k127_4512709_1	316274.Haur_0854	4.681e-15	85.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
CMS3_k127_4512709_0	926550.CLDAP_03390	1.852e-239	758.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
CMS3_k127_4528885_3	316274.Haur_3109	9.504e-10	64.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,374X2@32061|Chloroflexia	32061|Chloroflexia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS3_k127_4528885_1	926569.ANT_25040	9.686e-128	418.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_4528885_0	926569.ANT_25050	3.461e-266	833.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_4528885_2	326427.Cagg_2695	2.045e-31	129.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi,375MV@32061|Chloroflexia	32061|Chloroflexia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS3_k127_4532365_1	1116369.KB890024_gene1947	8.477e-85	286.0	COG1001@1|root,COG1001@2|Bacteria,1MVFP@1224|Proteobacteria,2TR1X@28211|Alphaproteobacteria,43H7K@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
CMS3_k127_4532365_2	118173.KB235914_gene1667	5.876e-72	259.0	COG4292@1|root,COG4292@2|Bacteria,1GBJ3@1117|Cyanobacteria,1HES6@1150|Oscillatoriales	1117|Cyanobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
CMS3_k127_4532365_0	1499967.BAYZ01000171_gene5534	1.738e-102	354.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
CMS3_k127_4532365_3	383372.Rcas_1937	1.06e-46	172.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi,375ZD@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_4532365_4	326427.Cagg_1149	5.205e-28	117.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi,375ZD@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_4532365_5	483219.LILAB_17000	3.365e-08	66.0	2CCFH@1|root,301N0@2|Bacteria,1R5U0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4537960_1	880073.Calab_2458	2.472e-31	126.0	COG2920@1|root,COG2920@2|Bacteria,2NQ6I@2323|unclassified Bacteria	2|Bacteria	P	DsrC like protein	dsrC	-	1.8.5.4	ko:K11179,ko:K17218	ko00920,ko04122,map00920,map04122	-	R10152	RC03155	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC,Pyr_redox_2
CMS3_k127_4537960_0	926550.CLDAP_11590	2.464e-64	224.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS3_k127_4537960_2	1192034.CAP_7816	3.716e-31	140.0	29X8Q@1|root,30IY3@2|Bacteria,1QZTR@1224|Proteobacteria,43CNP@68525|delta/epsilon subdivisions,2X7VZ@28221|Deltaproteobacteria,2YYEQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4539021_3	879308.HMPREF9130_0797	1.488e-08	56.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,22FZX@1570339|Peptoniphilaceae	186801|Clostridia	L	cog cog0116	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CMS3_k127_4539021_2	913865.DOT_3610	1.566e-100	341.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,24DRF@186801|Clostridia,2646E@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_4539021_1	1313172.YM304_01540	3.143e-101	341.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_4539021_0	1313172.YM304_01530	2.103e-109	363.0	COG1744@1|root,COG1744@2|Bacteria,2IEKS@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
CMS3_k127_4544143_0	998674.ATTE01000001_gene3923	1.167e-122	402.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,1RQD6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_4544143_2	876269.ARWA01000001_gene502	6.072e-53	192.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2U0S6@28211|Alphaproteobacteria,3NCGV@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS3_k127_4544143_3	307480.IW16_08765	0.0003978	48.0	2DB8K@1|root,2Z7S1@2|Bacteria,4NI7A@976|Bacteroidetes,1I0N2@117743|Flavobacteriia,3ZRFB@59732|Chryseobacterium	976|Bacteroidetes	I	Streptomycin adenylyltransferase	aadK	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
CMS3_k127_4544143_1	479435.Kfla_3072	4.004e-66	239.0	COG0515@1|root,COG0515@2|Bacteria,2I8SF@201174|Actinobacteria,4DRBE@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS3_k127_4546625_4	1394178.AWOO02000075_gene1990	4.552e-18	94.0	COG0615@1|root,COG0615@2|Bacteria,2IC88@201174|Actinobacteria,4EH6N@85012|Streptosporangiales	201174|Actinobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4546625_5	1089550.ATTH01000001_gene200	1.479e-09	68.0	COG0615@1|root,COG0615@2|Bacteria,4NY73@976|Bacteroidetes,1FK88@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4546625_2	1121405.dsmv_3782	9.859e-55	205.0	2DTTJ@1|root,32UVW@2|Bacteria,1NGQC@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_4546625_3	203124.Tery_1481	1.097e-38	162.0	COG1216@1|root,COG1216@2|Bacteria,1GQRA@1117|Cyanobacteria,1HBGK@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4546625_1	1122137.AQXF01000001_gene2601	9.433e-122	415.0	COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U2RD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_4546625_0	694427.Palpr_0130	3.894e-125	417.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,2FRUW@200643|Bacteroidia,22Y1X@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS3_k127_4548276_0	318996.AXAZ01000054_gene6391	1.034e-47	184.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2U7HC@28211|Alphaproteobacteria,3JZC0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_4548737_0	1382306.JNIM01000001_gene3257	1.338e-52	201.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS3_k127_4548737_1	1449353.JQMQ01000004_gene5927	4.544e-07	55.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria,2NI5U@228398|Streptacidiphilus	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_4553954_1	448385.sce0132	2.378e-119	392.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
CMS3_k127_4553954_2	1323663.AROI01000016_gene362	1.453e-70	247.0	COG2129@1|root,COG2129@2|Bacteria,1RFU9@1224|Proteobacteria,1S4S2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphoesterases, related to the Icc protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_4553954_4	926550.CLDAP_17190	5.73e-22	101.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS3_k127_4553954_0	926550.CLDAP_27600	4.632e-223	707.0	COG0488@1|root,COG0488@2|Bacteria,2G7WB@200795|Chloroflexi	200795|Chloroflexi	S	ABC transporter C-terminal domain	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_4553954_3	1051501.AYTL01000011_gene30	7.785e-68	240.0	COG2267@1|root,COG2267@2|Bacteria,1UIX9@1239|Firmicutes,4ISVM@91061|Bacilli,1ZREK@1386|Bacillus	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_45577_0	635013.TherJR_1789	1.88e-61	224.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,26015@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
CMS3_k127_45577_1	370438.PTH_1782	4.094e-49	193.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,26069@186807|Peptococcaceae	186801|Clostridia	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
CMS3_k127_45577_2	1173027.Mic7113_4898	1.532e-21	98.0	2B350@1|root,31VSS@2|Bacteria,1G7IM@1117|Cyanobacteria,1HDSR@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4558581_2	498761.HM1_1181	0.0006732	51.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia	186801|Clostridia	M	PFAM O-antigen polymerase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
CMS3_k127_4558581_1	472759.Nhal_2885	0.0005679	45.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	natSF	-	2.3.1.102,2.3.1.128	ko:K03789,ko:K03790,ko:K03896	ko00310,ko01120,map00310,map01120	-	R03168	RC00004,RC00865	ko00000,ko00001,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_3
CMS3_k127_4558581_0	504472.Slin_4255	3.951e-06	54.0	2BH02@1|root,32B06@2|Bacteria,4P6DW@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4562801_3	317936.Nos7107_0193	3.901e-46	177.0	COG0500@1|root,COG0500@2|Bacteria,1G9SQ@1117|Cyanobacteria,1HR4H@1161|Nostocales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_4562801_1	575540.Isop_2982	6.449e-96	331.0	COG1232@1|root,COG1232@2|Bacteria,2IYF5@203682|Planctomycetes	203682|Planctomycetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_4562801_0	1123075.AUDP01000009_gene1217	6.701e-98	336.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	tagH	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
CMS3_k127_4562801_2	671143.DAMO_0251	3.991e-49	185.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	wzm	-	-	ko:K01992,ko:K09690,ko:K09691,ko:K09692	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC2_membrane
CMS3_k127_4566722_3	926569.ANT_30190	2.732e-44	165.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_4566722_1	926550.CLDAP_06860	1.722e-71	247.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS3_k127_4566722_4	1396418.BATQ01000041_gene6269	4.965e-18	96.0	2E72P@1|root,331MA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4566722_2	926550.CLDAP_09190	8.031e-69	243.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4566722_0	1122176.KB903541_gene235	3.115e-138	445.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,1IYDA@117747|Sphingobacteriia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_4575885_0	1121346.KB899830_gene707	5.713e-293	907.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,26QZH@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 31 family	yicI	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
CMS3_k127_4578524_1	667014.Thein_0750	5.791e-41	158.0	COG0558@1|root,COG0558@2|Bacteria,2GH4T@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_4578524_0	926569.ANT_09910	3.039e-50	195.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_4578524_2	326427.Cagg_1790	2.578e-27	115.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi,374U5@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4585096_5	926569.ANT_29500	9.023e-54	195.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4585096_11	316274.Haur_0394	0.0005439	51.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi,375WU@32061|Chloroflexia	32061|Chloroflexia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4585096_8	926569.ANT_29480	3.706e-31	130.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_4585096_6	765420.OSCT_2098	1.907e-53	210.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi,376E4@32061|Chloroflexia	32061|Chloroflexia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4585096_2	459495.SPLC1_S020090	3.326e-165	538.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1G2KN@1117|Cyanobacteria,1HBXR@1150|Oscillatoriales	1117|Cyanobacteria	EH	Amino-transferase class IV	-	-	2.6.1.85,4.1.3.38	ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
CMS3_k127_4585096_3	102232.GLO73106DRAFT_00008030	4.123e-69	249.0	COG3380@1|root,COG3380@2|Bacteria,1G34R@1117|Cyanobacteria	1117|Cyanobacteria	S	NAD FAD-dependent oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_4585096_4	446470.Snas_6189	7.285e-59	211.0	COG0500@1|root,COG2226@2|Bacteria,2I636@201174|Actinobacteria,4EZP0@85014|Glycomycetales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_4585096_10	926550.CLDAP_22350	3.237e-14	80.0	COG1846@1|root,COG1846@2|Bacteria,2G9M0@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4585096_0	926550.CLDAP_22340	1.144e-229	726.0	COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4585096_1	926550.CLDAP_22330	1.57e-217	692.0	COG1132@1|root,COG1132@2|Bacteria,2G63W@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4585096_7	926550.CLDAP_04980	1.727e-45	171.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4585096_9	926550.CLDAP_04970	1.032e-20	103.0	COG5343@1|root,COG5343@2|Bacteria,2G7H8@200795|Chloroflexi	200795|Chloroflexi	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
CMS3_k127_458599_1	316274.Haur_2225	2.412e-51	189.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
CMS3_k127_458599_4	1549858.MC45_16550	0.0001514	48.0	COG3386@1|root,COG3386@2|Bacteria,1MVQM@1224|Proteobacteria,2U3TF@28211|Alphaproteobacteria,2K5IS@204457|Sphingomonadales	204457|Sphingomonadales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS3_k127_458599_3	1396418.BATQ01000075_gene683	1.625e-07	56.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_458599_0	485913.Krac_10420	3.858e-56	205.0	COG3393@1|root,COG3393@2|Bacteria,2G9G3@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_458599_2	552811.Dehly_0249	3.533e-23	102.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,34D4S@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS3_k127_4594523_1	926569.ANT_02800	6.036e-89	307.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CMS3_k127_4594523_3	266117.Rxyl_2810	5.704e-85	300.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_4594523_2	926569.ANT_08740	3.554e-88	297.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_4594523_7	1476876.JOJO01000001_gene7429	4.255e-22	102.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_4594523_6	66429.JOFL01000007_gene2370	1.035e-25	114.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS3_k127_4594523_4	1169152.AXVD01000023_gene3256	2.803e-77	269.0	COG2021@1|root,COG2021@2|Bacteria,2HIEG@201174|Actinobacteria,4G3VG@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4594523_5	485913.Krac_6990	1.379e-73	262.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4594523_0	485913.Krac_6991	1.49e-124	430.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_4598018_0	373994.Riv7116_2100	1.444e-77	266.0	COG1132@1|root,COG1132@2|Bacteria,1G0C0@1117|Cyanobacteria,1HKV0@1161|Nostocales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
CMS3_k127_4598018_2	861299.J421_2586	9.963e-08	63.0	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_4598018_1	1155718.KB891899_gene1824	1.066e-48	182.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	ko:K16033	ko01051,ko01052,ko01130,map01051,map01052,map01130	-	R09851	RC01363	ko00000,ko00001	-	-	-	Trp_halogenase
CMS3_k127_4598671_6	1229172.JQFA01000002_gene3999	1.88e-08	68.0	COG0265@1|root,COG0265@2|Bacteria,1G0XN@1117|Cyanobacteria,1H8PC@1150|Oscillatoriales	1117|Cyanobacteria	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PPC,Trypsin_2
CMS3_k127_4598671_1	102129.Lepto7375DRAFT_3929	1.683e-70	252.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,1H7AW@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS3_k127_4598671_4	666686.B1NLA3E_10560	6.145e-18	95.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4IQKZ@91061|Bacilli,1ZRKZ@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
CMS3_k127_4598671_5	485913.Krac_6117	9.821e-12	70.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_4598671_7	543632.JOJL01000006_gene9666	0.0001465	50.0	COG2267@1|root,COG2267@2|Bacteria,2IFFU@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_4598671_2	931627.MycrhDRAFT_0051	1.373e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,2IRKD@201174|Actinobacteria,239X8@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4598671_0	1121920.AUAU01000011_gene206	1.051e-93	340.0	COG3852@1|root,COG3852@2|Bacteria,3Y993@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_4598671_3	485916.Dtox_0803	9.096e-34	139.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24N7A@186801|Clostridia,262C9@186807|Peptococcaceae	186801|Clostridia	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS3_k127_460113_2	926550.CLDAP_19760	2.725e-102	342.0	COG0646@1|root,COG0646@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS3_k127_460113_4	926550.CLDAP_19770	9.246e-51	185.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
CMS3_k127_460113_0	926550.CLDAP_19780	1.353e-162	516.0	COG0685@1|root,COG0685@2|Bacteria,2G7NU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_460113_1	926550.CLDAP_19790	1.678e-136	441.0	COG1410@1|root,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_460113_3	926569.ANT_00050	4.804e-64	222.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_4605257_0	1226994.AMZB01000116_gene2539	1.135e-87	301.0	COG0388@1|root,COG0388@2|Bacteria,1P8FV@1224|Proteobacteria,1T9YI@1236|Gammaproteobacteria,1YDTJ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS3_k127_4605257_2	266117.Rxyl_0591	1.716e-36	147.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
CMS3_k127_4605257_1	266117.Rxyl_0591	3.222e-44	168.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
CMS3_k127_4605282_8	867845.KI911784_gene1107	1.733e-21	104.0	2B09D@1|root,31SK9@2|Bacteria	2|Bacteria	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
CMS3_k127_4605282_4	316274.Haur_0024	5.924e-60	218.0	COG0402@1|root,COG0402@2|Bacteria	2|Bacteria	F	S-adenosylhomocysteine deaminase activity	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_4605282_0	1519464.HY22_10360	6.893e-169	546.0	COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_4605282_5	530564.Psta_1556	2.627e-58	212.0	29525@1|root,2ZSEY@2|Bacteria,2IZ8U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4605282_11	446470.Snas_3977	5.355e-09	68.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,2H1NS@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
CMS3_k127_4605282_9	9371.XP_004715397.1	2.177e-17	95.0	COG0457@1|root,KOG1130@1|root,KOG0548@2759|Eukaryota,KOG1130@2759|Eukaryota,38GAN@33154|Opisthokonta,3BEXQ@33208|Metazoa,3CSRU@33213|Bilateria,484N1@7711|Chordata,493P3@7742|Vertebrata,3JA6E@40674|Mammalia,350YT@311790|Afrotheria	33208|Metazoa	OT	Tetratricopeptide repeat protein	TTC28	GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_7,TPR_8
CMS3_k127_4605282_10	8469.XP_007058416.1	4.183e-15	88.0	COG0457@1|root,KOG1130@1|root,KOG0548@2759|Eukaryota,KOG1130@2759|Eukaryota,38GAN@33154|Opisthokonta,3BEXQ@33208|Metazoa,3CSRU@33213|Bilateria,484N1@7711|Chordata,493P3@7742|Vertebrata	33208|Metazoa	O	cell division	TTC28	GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_16,TPR_7,TPR_8
CMS3_k127_4605282_12	1128421.JAGA01000002_gene1599	2.522e-06	61.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4605282_6	1461694.ATO9_09705	5.951e-30	138.0	COG1807@1|root,COG1807@2|Bacteria,1Q255@1224|Proteobacteria,2V9M6@28211|Alphaproteobacteria,2PF7E@252301|Oceanicola	28211|Alphaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4605282_2	1329516.JPST01000021_gene2521	1.554e-103	351.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,4HCM8@91061|Bacilli,27BI2@186824|Thermoactinomycetaceae	91061|Bacilli	H	Elongator protein 3, MiaB family, Radical SAM	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
CMS3_k127_4605282_3	316274.Haur_2162	1.303e-73	261.0	COG1427@1|root,COG1427@2|Bacteria	2|Bacteria	E	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	1.21.98.1,4.2.1.151	ko:K07081,ko:K11782,ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588,R10666	RC02329,RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CMS3_k127_4605282_7	1003195.SCAT_0234	4.084e-22	101.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS3_k127_4605282_1	316274.Haur_2163	3.577e-134	437.0	COG1060@1|root,COG1060@2|Bacteria,2G8HG@200795|Chloroflexi	2|Bacteria	H	Radical SAM enzyme that catalyzes the	mqnE	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_4614215_0	926569.ANT_29190	1.356e-116	383.0	COG0697@1|root,COG0697@2|Bacteria,2G98J@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_4614215_3	479431.Namu_2841	6.889e-17	95.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	BsuPI,LysM,PG_binding_1,Peptidase_M15_4
CMS3_k127_4614215_1	1196322.A370_05866	7.605e-113	384.0	COG0457@1|root,COG0457@2|Bacteria,1UJ9T@1239|Firmicutes,24CZA@186801|Clostridia,36G3G@31979|Clostridiaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
CMS3_k127_4614215_2	35754.JNYJ01000036_gene3658	1.8e-25	117.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DDFA@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4627533_1	747365.Thena_0744	2.118e-81	280.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,42F9V@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM DAHP synthetase I KDSA	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS3_k127_4627533_0	926550.CLDAP_35070	4.809e-106	361.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3275@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_4632470_2	1232443.BAIA02000045_gene2238	6.342e-09	57.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS3_k127_4632470_0	1238182.C882_3625	3.236e-129	426.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,2JTNS@204441|Rhodospirillales	204441|Rhodospirillales	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
CMS3_k127_4632470_1	1123023.JIAI01000007_gene1953	4.231e-41	153.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_4635218_1	1173027.Mic7113_2949	5.212e-82	295.0	COG0745@1|root,COG2199@1|root,COG4191@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS3_k127_4635218_0	1173028.ANKO01000127_gene4126	8.23e-126	417.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1G2RJ@1117|Cyanobacteria,1H9PS@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_4635218_2	1173263.Syn7502_01411	1.415e-51	189.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ETR2	-	1.8.1.9,3.1.3.3	ko:K00384,ko:K07315	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03021	-	-	-	HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_4637158_3	634497.HAH_1115	0.0007647	44.0	arCOG03392@1|root,arCOG03392@2157|Archaea,2XYTK@28890|Euryarchaeota,23WQS@183963|Halobacteria	183963|Halobacteria	S	Membrane-bound metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
CMS3_k127_4637158_2	1121288.AULL01000016_gene880	6.262e-17	91.0	2AC0T@1|root,311IM@2|Bacteria,4PGCB@976|Bacteroidetes,1IH7K@117743|Flavobacteriia,3ZT8H@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4637158_1	886293.Sinac_2689	6.097e-28	129.0	COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS3_k127_4637158_0	357808.RoseRS_2899	2.515e-71	250.0	COG0639@1|root,COG0639@2|Bacteria,2G71P@200795|Chloroflexi,375UU@32061|Chloroflexia	32061|Chloroflexia	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_464658_1	717606.PaecuDRAFT_4438	1.137e-34	141.0	COG0500@1|root,COG2226@2|Bacteria,1VR4R@1239|Firmicutes,4HUAS@91061|Bacilli,27563@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_464658_2	981085.XP_010099420.1	3.163e-24	110.0	28NA4@1|root,2QUVJ@2759|Eukaryota,37QBK@33090|Viridiplantae,3G9QP@35493|Streptophyta,4JFPI@91835|fabids	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_464658_0	926550.CLDAP_18930	1.399e-197	623.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_4647053_2	485913.Krac_7730	1.741e-36	152.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_4647053_0	56107.Cylst_4383	5.748e-121	404.0	2BZ5C@1|root,33RFU@2|Bacteria,1GNQZ@1117|Cyanobacteria,1HRUW@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4647053_1	329726.AM1_4962	1.649e-70	244.0	COG4894@1|root,COG4894@2|Bacteria,1G3DI@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4647053_3	402777.KB235903_gene2506	5.963e-09	67.0	COG2319@1|root,COG2319@2|Bacteria,1GQ9V@1117|Cyanobacteria,1HAG1@1150|Oscillatoriales	1117|Cyanobacteria	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WD40
CMS3_k127_4652356_0	255470.cbdbA1145	1.231e-112	376.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,34CUN@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS3_k127_4652356_1	525904.Tter_0491	0.0001562	45.0	COG0566@1|root,COG0566@2|Bacteria,2NQ0F@2323|unclassified Bacteria	2|Bacteria	J	tRNA rRNA methyltransferase	spoU	-	2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
CMS3_k127_4652397_4	1444309.JAQG01000087_gene2646	1.472e-20	96.0	COG2124@1|root,COG2124@2|Bacteria,1TSC5@1239|Firmicutes,4HBG5@91061|Bacilli,272TG@186822|Paenibacillaceae	91061|Bacilli	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_4652397_3	926569.ANT_01150	1.559e-32	134.0	COG1309@1|root,COG1309@2|Bacteria,2G9BD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
CMS3_k127_4652397_1	290317.Cpha266_1585	3.084e-41	156.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	DUF1735,Laminin_G_3,Patatin
CMS3_k127_4652397_0	640081.Dsui_1120	5.804e-44	167.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,2KWGG@206389|Rhodocyclales	206389|Rhodocyclales	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_4652397_2	240292.Ava_C0001	4.387e-33	133.0	COG0477@1|root,COG0477@2|Bacteria,1GHCR@1117|Cyanobacteria,1HKQS@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS3_k127_4660884_2	1379270.AUXF01000001_gene2683	9.1e-65	224.0	COG0008@1|root,COG0008@2|Bacteria,1ZTAC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS3_k127_4660884_3	765420.OSCT_2504	1.707e-61	225.0	COG0454@1|root,COG0456@2|Bacteria,2G8DV@200795|Chloroflexi,377HZ@32061|Chloroflexia	32061|Chloroflexia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_4660884_6	926569.ANT_22190	1.11e-25	121.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
CMS3_k127_4660884_9	324602.Caur_0412	2.118e-11	76.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2GABV@200795|Chloroflexi,3752H@32061|Chloroflexia	32061|Chloroflexia	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS3_k127_4660884_7	1227349.C170_17202	1.211e-20	103.0	COG0500@1|root,COG2226@2|Bacteria,1UYID@1239|Firmicutes,4HAJE@91061|Bacilli,26UBK@186822|Paenibacillaceae	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_4660884_4	1236976.JCM16418_541	9.002e-61	219.0	COG1670@1|root,COG1670@2|Bacteria,1VVI3@1239|Firmicutes	1239|Firmicutes	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_4660884_5	324602.Caur_0298	3.646e-34	151.0	COG0823@1|root,COG3210@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4660884_0	926550.CLDAP_37580	4.343e-165	530.0	COG0001@1|root,COG0001@2|Bacteria,2G7SS@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_4660884_8	882083.SacmaDRAFT_4868	1.361e-18	98.0	COG2423@1|root,COG2423@2|Bacteria,2H4D8@201174|Actinobacteria	201174|Actinobacteria	E	ornithine cyclodeaminase	ocd	-	1.5.1.51,4.3.1.12	ko:K01750,ko:K21721	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS3_k127_4660884_1	1121374.KB891575_gene882	7.264e-131	430.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1224|Proteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4661166_4	234267.Acid_3596	9.895e-06	55.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	57723|Acidobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
CMS3_k127_4661166_0	1499967.BAYZ01000061_gene5938	1.049e-47	195.0	COG2755@1|root,COG5617@1|root,COG2755@2|Bacteria,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria	2|Bacteria	E	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,YfhO,cNMP_binding
CMS3_k127_4661166_3	1128421.JAGA01000003_gene3738	6.762e-08	66.0	COG4745@1|root,COG4745@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4661166_1	765420.OSCT_2587	9.645e-44	183.0	COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia	32061|Chloroflexia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4661166_2	1242864.D187_008608	8.241e-20	104.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_4670788_0	1411685.U062_01425	2.17e-58	209.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,1RPHK@1236|Gammaproteobacteria,1J4Z2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	iAPECO1_1312.APECO1_2725,iE2348C_1286.E2348C_4048,iEC042_1314.EC042_4125,iECABU_c1320.ECABU_c42230,iECED1_1282.ECED1_4428,iECIAI39_1322.ECIAI39_4342,iECNA114_1301.ECNA114_3887,iECOK1_1307.ECOK1_4187,iECP_1309.ECP_3937,iECS88_1305.ECS88_4160,iECSF_1327.ECSF_3586,iECUMN_1333.ECUMN_4268,iEcSMS35_1347.EcSMS35_4106,iLF82_1304.LF82_0192,iNRG857_1313.NRG857_18615,iUMN146_1321.UM146_18880,iUMNK88_1353.UMNK88_4550,iUTI89_1310.UTI89_C4293,ic_1306.c4666	ATP-synt_A
CMS3_k127_4670788_2	1318628.MARLIPOL_10356	6.64e-33	128.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,468H6@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS3_k127_4670788_1	318161.Sden_3756	9.872e-41	155.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,2QADG@267890|Shewanellaceae	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664	ATP-synt_B
CMS3_k127_4670788_3	237609.PSAKL28_52710	1.267e-24	108.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSF_1195.SF3815,iSFxv_1172.SFxv_4157,iS_1188.S3953	OSCP
CMS3_k127_467820_2	468059.AUHA01000004_gene2164	1.362e-05	58.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,PPDK_N,Response_reg
CMS3_k127_467820_1	1500304.JQKY01000015_gene1919	6.001e-38	163.0	COG0642@1|root,COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
CMS3_k127_467820_0	706587.Desti_0324	6.159e-209	661.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2MQ8V@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CMS3_k127_4678544_1	316274.Haur_3200	2.841e-44	169.0	COG1309@1|root,COG1309@2|Bacteria,2GAFT@200795|Chloroflexi,375ZP@32061|Chloroflexia	32061|Chloroflexia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4678544_0	211165.AJLN01000148_gene2390	6.331e-82	282.0	COG0491@1|root,COG0491@2|Bacteria,1G9C5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_4678544_2	287986.DV20_29735	4.52e-28	132.0	COG5412@1|root,COG5412@2|Bacteria,2I383@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_4683002_2	926550.CLDAP_34290	8.845e-06	55.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Big_3_2,Cadherin-like,Calx-beta,DUF11,DUF4347,DUF4430,DUF915,FTP,HYR,I-set,PQQ_2,PT-HINT,Peptidase_M36,Pro-kuma_activ,RHS_repeat,VCBS
CMS3_k127_4683002_1	1499967.BAYZ01000038_gene2273	1.565e-111	373.0	COG0438@1|root,COG0438@2|Bacteria,2NQED@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS3_k127_4683002_0	717605.Theco_1785	1.236e-125	423.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26QA9@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	yknU	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4686693_0	1223410.KN050846_gene1006	7.985e-33	143.0	29YID@1|root,30KDH@2|Bacteria,4PG6A@976|Bacteroidetes,1I9NR@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4690902_3	272844.PAB1433	1.256e-15	82.0	COG0327@1|root,arCOG04454@2157|Archaea,2XT5G@28890|Euryarchaeota,242U7@183968|Thermococci	183968|Thermococci	S	metal ion binding	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS3_k127_4690902_0	926569.ANT_09940	3.205e-56	201.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi	200795|Chloroflexi	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS3_k127_4690902_2	926569.ANT_09970	2.342e-34	141.0	COG0394@1|root,COG0394@2|Bacteria,2G7C2@200795|Chloroflexi	200795|Chloroflexi	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_4690902_1	555088.DealDRAFT_1141	2.223e-43	170.0	COG1920@1|root,COG1920@2|Bacteria,1V86Y@1239|Firmicutes,24K51@186801|Clostridia	186801|Clostridia	S	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4697310_0	926550.CLDAP_27230	1.475e-69	242.0	COG1051@1|root,COG1051@2|Bacteria,2G7EC@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
CMS3_k127_4697310_1	861299.J421_2505	2.127e-20	100.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS3_k127_4701305_2	326427.Cagg_1632	3.421e-17	87.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,375UJ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS3_k127_4701305_1	357808.RoseRS_1781	4.107e-25	116.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
CMS3_k127_4701305_0	32049.SYNPCC7002_A0814	9.594e-63	223.0	COG0105@1|root,COG0105@2|Bacteria,1G4ZN@1117|Cyanobacteria,1GYKN@1129|Synechococcus	1117|Cyanobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS3_k127_4701305_3	926569.ANT_18700	0.0004784	51.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
CMS3_k127_4705251_3	485913.Krac_2132	5.863e-44	164.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	abmE	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_4705251_1	485913.Krac_2131	7.79e-169	538.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_4705251_4	160799.PBOR_32205	2.835e-06	58.0	COG1670@1|root,COG1670@2|Bacteria,1UZR2@1239|Firmicutes,4HC5N@91061|Bacilli,26SPB@186822|Paenibacillaceae	91061|Bacilli	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
CMS3_k127_4705251_2	1123023.JIAI01000004_gene7822	1.72e-70	248.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria,4E2MU@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_4705251_0	215803.DB30_8061	5.846e-237	742.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria,2YTXR@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme C-terminal domain	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
CMS3_k127_4708845_1	768670.Calni_0819	8.218e-05	50.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,2GF4M@200930|Deferribacteres	200930|Deferribacteres	C	PFAM cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
CMS3_k127_4708845_0	1323663.AROI01000010_gene3383	4.462e-130	433.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	pedH	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
CMS3_k127_4709860_1	926550.CLDAP_01050	4.976e-134	436.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS3_k127_4709860_0	357808.RoseRS_1038	2.954e-245	782.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi,37505@32061|Chloroflexia	32061|Chloroflexia	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS3_k127_4709860_3	1160718.SU9_13558	3.766e-06	56.0	COG1846@1|root,COG1846@2|Bacteria,2IPB7@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS3_k127_4709860_2	926550.CLDAP_04710	4.703e-72	256.0	COG2182@1|root,COG2182@2|Bacteria,2G91A@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
CMS3_k127_4710132_2	926550.CLDAP_29940	2.55e-33	144.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4710132_0	926550.CLDAP_29950	3.945e-192	617.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
CMS3_k127_4710132_1	479434.Sthe_3014	2.217e-165	537.0	COG0281@1|root,COG0281@2|Bacteria,2G65R@200795|Chloroflexi,27XFK@189775|Thermomicrobia	189775|Thermomicrobia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
CMS3_k127_4710416_0	765420.OSCT_0523	7.986e-104	356.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
CMS3_k127_4711763_7	653045.Strvi_5518	0.0008835	45.0	COG5412@1|root,COG5412@2|Bacteria,2I383@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_4711763_0	1449346.JQMO01000003_gene2880	5.046e-150	500.0	COG0464@1|root,COG0464@2|Bacteria,2I8CR@201174|Actinobacteria	201174|Actinobacteria	O	PFAM AAA ATPase central domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS3_k127_4711763_6	926550.CLDAP_40710	1.996e-07	56.0	2EU9B@1|root,33MRR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4711763_3	926550.CLDAP_13010	8.831e-54	208.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,TPR_12,Trans_reg_C
CMS3_k127_4711763_1	926560.KE387027_gene406	2.802e-100	334.0	COG2819@1|root,COG2819@2|Bacteria,1WMFX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
CMS3_k127_4711763_5	234267.Acid_3617	3.755e-36	147.0	COG4758@1|root,COG4758@2|Bacteria,3Y7Z2@57723|Acidobacteria	57723|Acidobacteria	S	N-terminal domain of toast_rack, DUF2154	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
CMS3_k127_4711763_4	926550.CLDAP_09650	3.198e-38	166.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
CMS3_k127_4711763_2	42256.RradSPS_1297	2.109e-69	241.0	COG0590@1|root,COG0590@2|Bacteria,2I9KR@201174|Actinobacteria	201174|Actinobacteria	FJ	CMP dCMP deaminase, zinc-binding	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
CMS3_k127_4713602_1	926560.KE387027_gene1021	1.248e-125	412.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4713602_2	316274.Haur_3717	5.738e-100	338.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS3_k127_4713602_0	765420.OSCT_1238	1.294e-147	477.0	COG1085@1|root,COG1085@2|Bacteria,2G6K5@200795|Chloroflexi,3759B@32061|Chloroflexia	32061|Chloroflexia	H	PFAM galactose-1-phosphate uridyl transferase domain protein	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
CMS3_k127_4714628_1	1000565.METUNv1_01823	1.713e-18	90.0	COG3832@1|root,COG3832@2|Bacteria,1REDB@1224|Proteobacteria,2VXCY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
CMS3_k127_4714628_0	1123508.JH636444_gene5587	1.882e-78	273.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02484,ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,Response_reg
CMS3_k127_471667_5	316274.Haur_2625	3.525e-54	194.0	COG0362@1|root,COG0362@2|Bacteria,2GBID@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS3_k127_471667_11	1121012.AUKX01000017_gene3100	9.597e-09	63.0	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,1HXKF@117743|Flavobacteriia,23GUI@178469|Arenibacter	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
CMS3_k127_471667_6	1234664.AMRO01000071_gene3120	4.75e-50	185.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,1WE9T@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix, Lux Regulon	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_471667_3	316274.Haur_1217	6.841e-84	302.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_471667_10	316274.Haur_1271	8.134e-12	70.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HATPase_c,Response_reg
CMS3_k127_471667_9	269799.Gmet_2789	1.974e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,42T3B@68525|delta/epsilon subdivisions,2WP8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS3_k127_471667_2	1461693.ATO10_03450	3.469e-92	306.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TUY3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_471667_8	1173026.Glo7428_4661	1.13e-42	161.0	COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria	1117|Cyanobacteria	K	MarR family transcriptional	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
CMS3_k127_471667_4	926550.CLDAP_26570	2.989e-62	229.0	COG0845@1|root,COG0845@2|Bacteria,2G8Q8@200795|Chloroflexi	200795|Chloroflexi	M	secretion protein HlyD family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS3_k127_471667_0	926550.CLDAP_26560	2.419e-250	803.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS3_k127_471667_1	383372.Rcas_4355	9.475e-111	370.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_471667_7	926550.CLDAP_26540	2.251e-45	169.0	COG1136@1|root,COG1136@2|Bacteria,2G6FP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4720236_0	1385935.N836_20445	2.98e-299	973.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
CMS3_k127_4720236_1	1121930.AQXG01000009_gene293	3.095e-43	176.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1IXIF@117747|Sphingobacteriia	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_472541_0	1499967.BAYZ01000061_gene5931	4.384e-210	664.0	COG0366@1|root,COG0366@2|Bacteria,2NP2D@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
CMS3_k127_472541_7	160799.PBOR_16515	1.325e-26	115.0	COG0457@1|root,COG0457@2|Bacteria,1VDZT@1239|Firmicutes,4HX3R@91061|Bacilli,26Z1E@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_472541_2	765420.OSCT_0816	7.306e-133	435.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi,375CE@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_472541_8	76114.ebA6442	8.904e-22	97.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VU78@28216|Betaproteobacteria,2KX1D@206389|Rhodocyclales	206389|Rhodocyclales	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
CMS3_k127_472541_6	479434.Sthe_1375	2.753e-27	117.0	COG0640@1|root,COG0640@2|Bacteria,2G7FZ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CMS3_k127_472541_1	357808.RoseRS_1707	9.101e-141	454.0	COG0701@1|root,COG0701@2|Bacteria,2G6DW@200795|Chloroflexi,376WA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS3_k127_472541_5	329726.AM1_0220	1.616e-88	310.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_472541_4	330214.NIDE0805	5.014e-89	324.0	COG0784@1|root,COG2198@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_472541_9	926560.KE387023_gene1701	4.396e-11	68.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_472541_10	67373.JOBF01000020_gene5698	0.0008703	43.0	COG1020@1|root,COG1020@2|Bacteria,2IEDH@201174|Actinobacteria	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
CMS3_k127_472541_3	1380394.JADL01000003_gene5090	1.043e-97	350.0	COG0642@1|root,COG2199@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JPVE@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_7,PAS_9,Response_reg
CMS3_k127_4730979_2	204669.Acid345_4289	7.64e-37	155.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,3Y59R@57723|Acidobacteria,2JNHF@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_4730979_1	243231.GSU0254	8.496e-45	170.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42RQX@68525|delta/epsilon subdivisions,2WNM1@28221|Deltaproteobacteria,43U8H@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4730979_0	5759.rna_EHI_169340-1	2.285e-71	266.0	2D6RI@1|root,2T2RS@2759|Eukaryota,3XC2S@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4730979_3	1234664.AMRO01000079_gene569	3.277e-29	135.0	COG1525@1|root,COG3204@1|root,COG1525@2|Bacteria,COG3204@2|Bacteria,1V7X8@1239|Firmicutes,4HJJI@91061|Bacilli,1WH7K@129337|Geobacillus	91061|Bacilli	L	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,SNase
CMS3_k127_4730979_4	591019.Shell_0193	7.097e-06	54.0	arCOG04155@1|root,arCOG04155@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4738994_0	926550.CLDAP_34280	3.694e-83	278.0	COG1012@1|root,COG1012@2|Bacteria,2G5JZ@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_4738994_5	485913.Krac_4709	2.938e-33	142.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_4738994_4	765420.OSCT_1929	2.775e-37	152.0	2E65M@1|root,330UB@2|Bacteria	2|Bacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_4738994_3	1207063.P24_09791	3.554e-48	178.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria,2JSQY@204441|Rhodospirillales	204441|Rhodospirillales	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS3_k127_4738994_1	1318628.MARLIPOL_01155	3.165e-63	227.0	COG0500@1|root,COG2226@2|Bacteria,1QYC9@1224|Proteobacteria,1S4V4@1236|Gammaproteobacteria,46900@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
CMS3_k127_4738994_6	313628.LNTAR_05834	1.153e-20	99.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,FR47
CMS3_k127_4738994_2	1114856.C496_10626	4.17e-53	192.0	COG2303@1|root,arCOG02233@2157|Archaea,2XV32@28890|Euryarchaeota,23THY@183963|Halobacteria	183963|Halobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_4755078_0	526227.Mesil_0382	5.963e-279	875.0	COG1505@1|root,COG1505@2|Bacteria,1WMDW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_4756451_0	1449069.JMLO01000008_gene3495	2.12e-91	316.0	COG0451@1|root,COG0451@2|Bacteria,2GN2J@201174|Actinobacteria,4FZ35@85025|Nocardiaceae	201174|Actinobacteria	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS3_k127_4756451_1	1128421.JAGA01000003_gene2997	8.505e-68	246.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_4756451_2	237609.PSAKL28_11110	6.014e-25	113.0	COG2141@1|root,COG2141@2|Bacteria,1RGXC@1224|Proteobacteria,1SHMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4757938_0	1304865.JAGF01000001_gene2907	1.344e-165	535.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria	201174|Actinobacteria	G	alpha amylase, catalytic	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
CMS3_k127_4757938_2	985665.HPL003_25950	9.363e-14	85.0	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
CMS3_k127_4757938_1	1082931.KKY_2561	1.531e-62	229.0	COG2342@1|root,COG2342@2|Bacteria,1N2HD@1224|Proteobacteria,2UEA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glycoside-hydrolase family GH114	-	-	6.1.1.16	ko:K01884	ko00970,map00970	M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Glyco_hydro_114,HemolysinCabind
CMS3_k127_4761436_6	670487.Ocepr_0782	2.966e-10	72.0	COG0664@1|root,COG0664@2|Bacteria,1WJXH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_4761436_5	765420.OSCT_2174	3.013e-67	237.0	COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia	32061|Chloroflexia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
CMS3_k127_4761436_4	765420.OSCT_2174	1.156e-104	346.0	COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia	32061|Chloroflexia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
CMS3_k127_4761436_2	1499967.BAYZ01000009_gene5357	2.124e-169	555.0	COG0840@1|root,COG2203@1|root,COG0840@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	pyp	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,HATPase_c,HisKA,MCPsignal,PAS,PAS_3,dCache_1
CMS3_k127_4761436_1	1173024.KI912148_gene3267	2.651e-200	642.0	COG0747@1|root,COG0747@2|Bacteria,1G0S3@1117|Cyanobacteria,1JKNJ@1189|Stigonemataceae	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_4761436_0	32057.KB217478_gene2004	4.679e-267	861.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,PP-binding
CMS3_k127_4761436_3	246197.MXAN_3636	8.532e-146	486.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS3_k127_4762756_0	309801.trd_0354	1.272e-119	399.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_4762756_1	1382356.JQMP01000004_gene63	3.993e-91	312.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,27Y2S@189775|Thermomicrobia	189775|Thermomicrobia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS3_k127_476360_3	926550.CLDAP_07350	5.602e-27	121.0	COG0454@1|root,COG0456@2|Bacteria,2G9KU@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_476360_2	221288.JH992901_gene1227	1.137e-35	148.0	COG3393@1|root,COG3393@2|Bacteria,1G551@1117|Cyanobacteria,1JJ54@1189|Stigonemataceae	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,FR47
CMS3_k127_476360_1	479434.Sthe_0796	7.584e-278	868.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS3_k127_476360_0	926550.CLDAP_10300	0.0	1176.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_4771390_0	1121015.N789_12645	6.21e-105	382.0	COG2885@1|root,COG2885@2|Bacteria,1QVSX@1224|Proteobacteria	1224|Proteobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,OmpA
CMS3_k127_4771866_8	383372.Rcas_2088	2.581e-38	146.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi,375NS@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS3_k127_4771866_3	926569.ANT_10420	1.961e-107	362.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS3_k127_4771866_10	926569.ANT_10430	3.253e-19	94.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS3_k127_4771866_9	1449126.JQKL01000022_gene112	3.824e-33	130.0	COG0713@1|root,COG0713@2|Bacteria,1V9Z8@1239|Firmicutes,24NKG@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS3_k127_4771866_0	926569.ANT_10450	1.197e-207	669.0	COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CMS3_k127_4771866_1	926569.ANT_10460	3.143e-192	614.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS3_k127_4771866_2	383372.Rcas_2098	1.879e-142	469.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi,374ZX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_4771866_4	926569.ANT_10480	7.059e-106	361.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS3_k127_4771866_7	926569.ANT_10520	3.449e-45	179.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS3_k127_4771866_11	926569.ANT_10530	1.168e-14	76.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS3_k127_4771866_6	926569.ANT_10540	1.175e-46	176.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS3_k127_4771866_5	1173025.GEI7407_2335	2.106e-99	331.0	COG2013@1|root,COG2013@2|Bacteria,1G2XX@1117|Cyanobacteria,1H9ZF@1150|Oscillatoriales	1117|Cyanobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
CMS3_k127_4784294_3	717605.Theco_2070	1.095e-64	225.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,26QD1@186822|Paenibacillaceae	91061|Bacilli	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS3_k127_4784294_1	926569.ANT_31010	4.418e-95	316.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_4784294_4	926569.ANT_03510	4.34e-56	201.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS3_k127_4784294_2	926550.CLDAP_41140	9.141e-89	299.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS3_k127_4784294_5	1009370.ALO_14272	2.223e-34	142.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4H4UZ@909932|Negativicutes	909932|Negativicutes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS3_k127_4784294_0	926550.CLDAP_16500	4.278e-132	429.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
CMS3_k127_4784294_6	383372.Rcas_2965	3.975e-28	120.0	COG3304@1|root,COG3304@2|Bacteria,2G74I@200795|Chloroflexi,375XJ@32061|Chloroflexia	32061|Chloroflexia	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
CMS3_k127_4785455_1	926550.CLDAP_37380	2.729e-42	158.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_4785455_0	1075090.GOAMR_46_01050	3.624e-110	367.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_4794807_1	1120999.JONM01000004_gene3572	6.8e-77	261.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,2KPWM@206351|Neisseriales	206351|Neisseriales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS3_k127_4794807_0	1144319.PMI16_00397	1.67e-79	284.0	COG1565@1|root,COG1565@2|Bacteria,1N06M@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4794807_2	521674.Plim_1218	5.728e-12	76.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4797515_2	1394178.AWOO02000020_gene7445	8.444e-17	86.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS3_k127_4797515_0	426117.M446_1932	1.194e-90	314.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,1JWG7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
CMS3_k127_4797515_1	1003195.SCAT_0451	1.163e-37	158.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator superfamily	stp	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_4797515_3	1227487.C474_15694	3.748e-15	76.0	COG1053@1|root,arCOG00571@2157|Archaea,2Y855@28890|Euryarchaeota,24152@183963|Halobacteria	183963|Halobacteria	C	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
CMS3_k127_4797884_1	880072.Desac_2104	8.514e-66	235.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2MSIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS3_k127_4797884_0	479434.Sthe_0099	2.499e-183	584.0	COG0243@1|root,COG0243@2|Bacteria,2GABT@200795|Chloroflexi,27Z9X@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_4800762_10	926569.ANT_09040	1.068e-22	107.0	COG0265@1|root,COG0265@2|Bacteria,2G821@200795|Chloroflexi	200795|Chloroflexi	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
CMS3_k127_4800762_3	926550.CLDAP_07100	5.061e-102	337.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_4800762_13	1128421.JAGA01000002_gene667	3.287e-06	59.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_2,TPR_8,Trypsin_2
CMS3_k127_4800762_8	926569.ANT_26660	1.292e-39	149.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_4800762_0	926569.ANT_26670	1.886e-259	809.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_4800762_14	1127673.GLIP_1435	0.000299	52.0	COG0457@1|root,COG0457@2|Bacteria,1REXI@1224|Proteobacteria,1SYRM@1236|Gammaproteobacteria,46CY6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5,TPR_16,TPR_19,TPR_8
CMS3_k127_4800762_9	926569.ANT_16750	1.193e-25	111.0	COG0125@1|root,COG0125@2|Bacteria,2GBP3@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4800762_7	926569.ANT_16730	5.734e-62	221.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CMS3_k127_4800762_2	335543.Sfum_2802	5.864e-169	555.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS3_k127_4800762_12	269800.Tfu_1753	1.682e-12	68.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4EHE2@85012|Streptosporangiales	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS3_k127_4800762_1	926550.CLDAP_38260	3.594e-226	720.0	COG0507@1|root,COG0632@1|root,COG0507@2|Bacteria,COG0632@2|Bacteria,2G626@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS3_k127_4800762_4	485913.Krac_5027	1.072e-94	342.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_4800762_6	1121918.ARWE01000001_gene495	6.993e-72	248.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS3_k127_4800762_5	211165.AJLN01000116_gene3204	2.767e-77	268.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
CMS3_k127_4801855_11	1120971.AUCA01000003_gene1434	2.406e-07	59.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1TRF1@1239|Firmicutes,4HI50@91061|Bacilli	91061|Bacilli	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CMS3_k127_4801855_9	930171.Asphe3_21100	1.748e-15	89.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS3_k127_4801855_4	926569.ANT_08150	1.646e-102	343.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4801855_1	323261.Noc_1879	9.084e-147	490.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,1RQNE@1236|Gammaproteobacteria,1WWYQ@135613|Chromatiales	135613|Chromatiales	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS3_k127_4801855_2	926569.ANT_23640	7.397e-124	417.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
CMS3_k127_4801855_3	926550.CLDAP_39300	5.583e-106	372.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
CMS3_k127_4801855_8	1128421.JAGA01000003_gene3454	2.502e-41	163.0	COG3346@1|root,COG3346@2|Bacteria	2|Bacteria	S	mitochondrial respiratory chain complex IV assembly	surf1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
CMS3_k127_4801855_10	926550.CLDAP_10570	1.389e-11	74.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11,SdrD_B
CMS3_k127_4801855_6	926550.CLDAP_10580	5.057e-55	204.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
CMS3_k127_4801855_5	926550.CLDAP_10590	2.418e-68	239.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
CMS3_k127_4801855_0	1380390.JIAT01000014_gene6065	2.63e-151	499.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CS3H@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CMS3_k127_4801855_7	926569.ANT_05310	4.977e-48	183.0	COG1622@1|root,COG2010@1|root,COG2197@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,COG2197@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
CMS3_k127_4803043_0	1121920.AUAU01000011_gene206	6.617e-70	260.0	COG3852@1|root,COG3852@2|Bacteria,3Y993@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_4805232_2	589865.DaAHT2_0731	2.319e-29	137.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42M4Y@68525|delta/epsilon subdivisions,2WKKD@28221|Deltaproteobacteria,2MIK0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
CMS3_k127_4805232_3	306281.AJLK01000158_gene5361	4.871e-28	133.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1FZXP@1117|Cyanobacteria,1JJSB@1189|Stigonemataceae	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc,PAS,PAS_8,PAS_9
CMS3_k127_4805232_1	926550.CLDAP_31390	6.486e-65	252.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926550.CLDAP_31390|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4805232_0	316274.Haur_1811	3.616e-97	331.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	LTD,PKD,Reprolysin_4,Reprolysin_5
CMS3_k127_4805974_3	765420.OSCT_1590	1.537e-26	122.0	COG0840@1|root,COG1366@1|root,COG0840@2|Bacteria,COG1366@2|Bacteria,2GBRS@200795|Chloroflexi,375NB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	HAMP,STAS
CMS3_k127_4805974_2	1079460.ATTQ01000010_gene82	6.458e-36	149.0	COG1879@1|root,COG1879@2|Bacteria,1PCD4@1224|Proteobacteria,2V6MA@28211|Alphaproteobacteria,4BF5P@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
CMS3_k127_4805974_1	313612.L8106_00975	8.978e-50	184.0	COG2755@1|root,COG2755@2|Bacteria,1G3CB@1117|Cyanobacteria,1HAHZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Lysophospholipase l1-like esterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_4805974_0	383372.Rcas_1143	1.442e-50	184.0	2ECZ8@1|root,336W9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4805974_4	467661.RKLH11_4080	2.623e-13	82.0	COG0737@1|root,COG2374@1|root,COG2931@1|root,COG3391@1|root,COG0737@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1MX03@1224|Proteobacteria,2TTUP@28211|Alphaproteobacteria,3ZGID@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	MA20_07595	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
CMS3_k127_4806620_1	1297742.A176_00961	3.037e-99	333.0	COG0451@1|root,COG0451@2|Bacteria,1RBSM@1224|Proteobacteria,42XUG@68525|delta/epsilon subdivisions,2WTSY@28221|Deltaproteobacteria,2YX8Q@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS3_k127_4806620_0	1123288.SOV_4c07550	4.249e-110	372.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4H3I7@909932|Negativicutes	909932|Negativicutes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS3_k127_4808868_0	1128421.JAGA01000002_gene1086	1.086e-143	462.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	yicI	GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
CMS3_k127_4808868_2	1237149.C900_05039	5.609e-118	391.0	2C1EG@1|root,2Z7MZ@2|Bacteria,4NYQE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4808868_1	991.IW20_21400	1.931e-126	422.0	COG1231@1|root,COG1231@2|Bacteria,4NJCS@976|Bacteroidetes,1I8BH@117743|Flavobacteriia,2NVTA@237|Flavobacterium	976|Bacteroidetes	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_481202_0	357808.RoseRS_4521	2.138e-115	378.0	COG1834@1|root,COG1834@2|Bacteria,2G7QT@200795|Chloroflexi,377RX@32061|Chloroflexia	32061|Chloroflexia	E	PFAM amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
CMS3_k127_481202_1	415426.Hbut_0621	1.635e-100	341.0	COG2309@1|root,arCOG01888@2157|Archaea,2XPZP@28889|Crenarchaeota	28889|Crenarchaeota	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_4819469_8	497964.CfE428DRAFT_0631	4.076e-23	102.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_4819469_9	926550.CLDAP_09140	7.796e-09	57.0	COG3832@1|root,COG3832@2|Bacteria,2G9I3@200795|Chloroflexi	200795|Chloroflexi	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_4819469_0	383372.Rcas_1696	1.803e-186	592.0	COG0624@1|root,COG0624@2|Bacteria,2G62C@200795|Chloroflexi,3771C@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_4819469_4	1123247.AUIJ01000039_gene925	6.62e-116	394.0	COG1409@1|root,COG1409@2|Bacteria,1QI4K@1224|Proteobacteria,2TV5Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_4819469_2	686340.Metal_3113	3.379e-151	508.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,1S0A9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
CMS3_k127_4819469_7	998674.ATTE01000001_gene3077	5.54e-46	177.0	296JA@1|root,2ZTUV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4819469_1	1123277.KB893197_gene6105	1.707e-157	528.0	COG1520@1|root,COG3266@1|root,COG1520@2|Bacteria,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,47QPM@768503|Cytophagia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_4819469_5	926550.CLDAP_19470	1.071e-96	354.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_4819469_3	661478.OP10G_0994	1.565e-128	427.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS3_k127_4819469_6	318464.IO99_06635	1.019e-56	209.0	COG0500@1|root,COG2226@2|Bacteria,1UFKC@1239|Firmicutes,24H53@186801|Clostridia,36I5D@31979|Clostridiaceae	186801|Clostridia	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Ubie_methyltran
CMS3_k127_4820340_0	926569.ANT_22150	3.394e-195	618.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_4820340_1	926569.ANT_22140	2.629e-104	343.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
CMS3_k127_4820625_0	945713.IALB_2586	6.214e-82	287.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Lipase_GDSL_2,Polysacc_deac_1,SLH
CMS3_k127_4821534_4	485913.Krac_5820	6.853e-33	139.0	COG5635@1|root,COG5635@2|Bacteria,2G8PW@200795|Chloroflexi	200795|Chloroflexi	T	COGs COG5635 NTPase (NACHT family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,NACHT
CMS3_k127_4821534_1	449447.MAE_11610	8.922e-131	448.0	28JCI@1|root,2Z976@2|Bacteria,1G4JJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4821534_0	102129.Lepto7375DRAFT_0514	4.308e-245	814.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	-
CMS3_k127_4821534_3	102129.Lepto7375DRAFT_0515	2.273e-58	228.0	2ECHJ@1|root,336FT@2|Bacteria	2|Bacteria	S	Anthrax toxin LF subunit	-	-	-	-	-	-	-	-	-	-	-	-	Anthrax_toxA
CMS3_k127_4821534_2	449447.MAE_11540	1.387e-71	255.0	COG1413@1|root,COG1413@2|Bacteria,1G2TK@1117|Cyanobacteria	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4840626_0	103733.JNYO01000020_gene1908	3.363e-208	658.0	COG1231@1|root,COG1231@2|Bacteria,2GMV0@201174|Actinobacteria,4DZ53@85010|Pseudonocardiales	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS3_k127_4840626_3	926550.CLDAP_08450	1.999e-39	161.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G96Q@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
CMS3_k127_4840626_1	926550.CLDAP_08440	5.556e-74	255.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4840626_4	1453500.AT05_05250	2.59e-21	109.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CHU_C,PKD,Peptidase_S8,fn3
CMS3_k127_4840626_2	1239962.C943_03552	4.105e-69	249.0	COG1835@1|root,COG1835@2|Bacteria,4NHPE@976|Bacteroidetes,47JWZ@768503|Cytophagia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
CMS3_k127_4844358_0	1128421.JAGA01000002_gene1140	2.093e-221	698.0	COG4799@1|root,COG4799@2|Bacteria,2NQBT@2323|unclassified Bacteria	2|Bacteria	I	Carboxyl transferase domain	mccB	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_4844358_5	926550.CLDAP_08190	8.776e-27	117.0	COG2606@1|root,COG2606@2|Bacteria,2G9C3@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS3_k127_4844358_4	1459636.NTE_02082	4.201e-42	168.0	COG0834@1|root,arCOG01799@2157|Archaea	2157|Archaea	ET	PFAM Extracellular solute-binding protein, family 3	glnH1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS3_k127_4844358_3	2002.JOEQ01000083_gene945	2.562e-65	240.0	COG4188@1|root,COG4188@2|Bacteria,2GJVV@201174|Actinobacteria,4EMX2@85012|Streptosporangiales	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS3_k127_4844358_2	926550.CLDAP_21600	1.969e-100	338.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_4844358_6	391037.Sare_4064	1.308e-20	96.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4D9TH@85008|Micromonosporales	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_4844358_7	1267580.AF6_2100	8.311e-10	70.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,21WDW@150247|Anoxybacillus	91061|Bacilli	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS3_k127_4844358_1	926569.ANT_11040	9.619e-168	544.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,2G9NH@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS3_k127_4844358_8	208439.AJAP_19275	7.233e-08	58.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,NB-ARC,TPR_12
CMS3_k127_4844952_5	232348.ADXL01000050_gene2071	4.251e-48	188.0	COG0531@1|root,COG0531@2|Bacteria,1G33D@1117|Cyanobacteria,1H04V@1129|Synechococcus	1117|Cyanobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS3_k127_4844952_3	391613.RTM1035_07028	2.1e-87	303.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,46QKF@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_4844952_2	485913.Krac_10666	6.723e-92	318.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi	2|Bacteria	E	aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_4844952_0	1128421.JAGA01000002_gene816	1.399e-198	629.0	COG1233@1|root,COG1233@2|Bacteria,2NQAT@2323|unclassified Bacteria	2|Bacteria	Q	Flavin containing amine oxidoreductase	pys	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_4844952_8	1177594.MIC448_2190008	1.342e-27	118.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K03090,ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS3_k127_4844952_9	485913.Krac_2638	5.26e-25	108.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS3_k127_4844952_1	485913.Krac_2637	3.219e-152	490.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CMS3_k127_4844952_7	485913.Krac_2637	5.115e-30	123.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CMS3_k127_4844952_6	485913.Krac_9652	5.736e-46	177.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_4851109_0	926550.CLDAP_25730	5.277e-76	268.0	COG2721@1|root,COG2721@2|Bacteria,2G8E3@200795|Chloroflexi	200795|Chloroflexi	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	-	-	-	-	-	-	-	-	-	-	GD_AH_C
CMS3_k127_4851109_2	195103.CPF_2928	3.388e-37	147.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia,36JKZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561
CMS3_k127_4851109_1	926560.KE387027_gene366	5.868e-40	155.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_4851109_3	467705.SGO_1814	1.998e-11	71.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes	1239|Firmicutes	T	COG3629 DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS3_k127_4856494_4	517418.Ctha_0577	9.9e-08	62.0	COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_4856494_3	926550.CLDAP_20460	2.838e-48	181.0	COG0344@1|root,COG0344@2|Bacteria,2G8ZF@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS3_k127_4856494_1	926550.CLDAP_20470	2.632e-65	234.0	COG2324@1|root,COG2324@2|Bacteria,2G7BI@200795|Chloroflexi	200795|Chloroflexi	I	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Caroten_synth
CMS3_k127_4856494_2	649638.Trad_2243	7.437e-58	211.0	COG0204@1|root,COG2324@1|root,COG0204@2|Bacteria,COG2324@2|Bacteria,1WI4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM lycopene cyclase domain	-	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
CMS3_k127_4856494_0	926550.CLDAP_20410	1.386e-142	465.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	2|Bacteria	C	PFAM Cytochrome P450	cyp139A3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_4857394_0	1279009.ADICEAN_03579	3.748e-123	411.0	COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,47N9X@768503|Cytophagia	976|Bacteroidetes	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS3_k127_4857394_1	1121382.JQKG01000068_gene2668	2.799e-33	136.0	COG1403@1|root,COG1403@2|Bacteria,1WICD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS3_k127_4857394_2	391603.FBALC1_04647	2.753e-16	93.0	COG2885@1|root,COG3291@1|root,COG4447@1|root,COG2885@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4P2UU@976|Bacteroidetes,1HYAX@117743|Flavobacteriia	976|Bacteroidetes	DZ	TIGRFAM Bacterial surface protein 26-residue repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,DUF285,TIG,TSP_3
CMS3_k127_4857394_3	252305.OB2597_04023	2.063e-06	53.0	COG3103@1|root,COG4991@2|Bacteria,1RBPM@1224|Proteobacteria,2U6W2@28211|Alphaproteobacteria,2PE6B@252301|Oceanicola	28211|Alphaproteobacteria	T	Protein of unknown function (DUF1236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
CMS3_k127_485810_0	926550.CLDAP_08400	2.21e-66	248.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	2|Bacteria	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12
CMS3_k127_485810_3	1284679.HMPREF1626_06810	6.349e-08	57.0	COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria,4D3ZM@85005|Actinomycetales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_485810_4	985867.AEWF01000001_gene2046	0.0002572	51.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,47F2C@766|Rickettsiales	766|Rickettsiales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	hflC1	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
CMS3_k127_485810_1	326427.Cagg_0012	8.579e-15	87.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
CMS3_k127_4859974_0	945713.IALB_1070	2.4e-247	773.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_4861237_0	400682.PAC_15717354	2.501e-11	77.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa	33208|Metazoa	M	protein depalmitoleylation	-	-	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_4861237_1	400682.PAC_15717354	2.003e-07	64.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa	33208|Metazoa	M	protein depalmitoleylation	-	-	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_4863166_1	1121946.AUAX01000002_gene324	3.518e-71	249.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	ko:K18399	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_4863166_2	1040987.AZUY01000034_gene2156	1.64e-50	190.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2TTVF@28211|Alphaproteobacteria,43PBP@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS3_k127_4863166_0	448385.sce1233	9.434e-72	262.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YTXS@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
CMS3_k127_4863166_3	926550.CLDAP_02220	3.678e-09	69.0	COG2335@1|root,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS3_k127_4865118_3	926550.CLDAP_24160	1.383e-43	163.0	COG4334@1|root,COG4334@2|Bacteria,2G8RW@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2255
CMS3_k127_4865118_0	1163409.UUA_11001	9.359e-182	584.0	COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,1RQUU@1236|Gammaproteobacteria,1X4D6@135614|Xanthomonadales	135614|Xanthomonadales	S	Phage tail sheath C-terminal domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
CMS3_k127_4865118_1	666685.R2APBS1_0486	8.912e-77	261.0	2DB76@1|root,2Z7JZ@2|Bacteria,1R41X@1224|Proteobacteria,1S1J8@1236|Gammaproteobacteria,1X4KH@135614|Xanthomonadales	135614|Xanthomonadales	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
CMS3_k127_4865118_2	439235.Dalk_4363	5.396e-74	263.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_4870595_2	926550.CLDAP_29040	1.057e-64	229.0	COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi	200795|Chloroflexi	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS3_k127_4870595_6	1128421.JAGA01000003_gene3091	0.0004597	53.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_4870595_5	1519464.HY22_06685	1.087e-26	124.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria	2|Bacteria	GT	kinase activity	-	-	2.7.3.13,2.7.9.1,2.7.9.2	ko:K01006,ko:K01007,ko:K22424	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS3_k127_4870595_0	1232410.KI421428_gene1184	1.147e-144	480.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,43S4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS3_k127_4870595_1	926550.CLDAP_17010	1.302e-102	345.0	COG0701@1|root,COG0701@2|Bacteria,2G6EM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS3_k127_4870595_3	926550.CLDAP_17020	2.273e-57	207.0	COG3689@1|root,COG3689@2|Bacteria,2G73M@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF1980)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1980
CMS3_k127_4870595_4	926550.CLDAP_17030	3.124e-29	126.0	COG0823@1|root,COG0823@2|Bacteria,2G8W2@200795|Chloroflexi	200795|Chloroflexi	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Big_5,PD40
CMS3_k127_4876509_1	195250.CM001776_gene908	7.018e-06	51.0	2DNUQ@1|root,32Z94@2|Bacteria,1G5ZA@1117|Cyanobacteria,1H1AC@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
CMS3_k127_4876509_0	290397.Adeh_2304	6.475e-317	987.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.3,1.8.5.5	ko:K07306,ko:K08352	ko00920,ko01120,map00920,map01120	-	R09501,R10149	RC02555,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_4877654_2	926550.CLDAP_01820	5.894e-70	243.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS3_k127_4877654_0	349161.Dred_1159	7.291e-97	332.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
CMS3_k127_4877654_3	1123277.KB893197_gene6105	2.042e-66	245.0	COG1520@1|root,COG3266@1|root,COG1520@2|Bacteria,COG3266@2|Bacteria,4NQBS@976|Bacteroidetes,47QPM@768503|Cytophagia	976|Bacteroidetes	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_4877654_1	1125863.JAFN01000001_gene842	2.237e-83	282.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42M0U@68525|delta/epsilon subdivisions,2WJR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	LysM,MS_channel,TM_helix
CMS3_k127_487893_1	671143.DAMO_3023	6.246e-24	107.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
CMS3_k127_487893_0	398767.Glov_2638	1.505e-64	227.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
CMS3_k127_4879215_7	1121430.JMLG01000017_gene278	3.626e-52	189.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,261I9@186807|Peptococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS3_k127_4879215_5	459349.CLOAM0931	1.893e-78	269.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS3_k127_4879215_6	765420.OSCT_2229	2.649e-78	284.0	COG2843@1|root,COG2843@2|Bacteria,2GB5U@200795|Chloroflexi,377DF@32061|Chloroflexia	32061|Chloroflexia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS3_k127_4879215_0	765420.OSCT_2228	1.59e-203	666.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,YARHG,zinc_ribbon_2
CMS3_k127_4879215_10	272563.CD630_11350	3.706e-13	83.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1V343@1239|Firmicutes,24YXC@186801|Clostridia,25RH0@186804|Peptostreptococcaceae	186801|Clostridia	MT	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
CMS3_k127_4879215_3	926550.CLDAP_39920	2.936e-103	358.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
CMS3_k127_4879215_8	1499967.BAYZ01000118_gene3252	4.301e-46	170.0	COG0662@1|root,COG0662@2|Bacteria,2NRIV@2323|unclassified Bacteria	2|Bacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_4879215_2	324602.Caur_0861	5.274e-112	373.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS3_k127_4879215_4	357808.RoseRS_0390	4.55e-103	342.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,375AU@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS3_k127_4879215_9	479434.Sthe_3410	7.217e-30	130.0	COG0500@1|root,COG2890@1|root,COG2226@2|Bacteria,COG2890@2|Bacteria,2G9F9@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4879215_1	448385.sce7868	6.455e-179	587.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4215,PPC,P_proprotein
CMS3_k127_4884433_1	518766.Rmar_2430	8.44e-68	240.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes	976|Bacteroidetes	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS3_k127_4884433_0	478741.JAFS01000001_gene1200	5.036e-87	292.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,37GED@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_4898955_1	926550.CLDAP_06090	3.078e-80	271.0	COG3415@1|root,COG3415@2|Bacteria,2G8GG@200795|Chloroflexi	200795|Chloroflexi	L	InterPro IPR009057	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32
CMS3_k127_4898955_0	272134.KB731326_gene141	8.793e-90	305.0	COG3335@1|root,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
CMS3_k127_4905138_4	234267.Acid_1096	1.834e-16	89.0	COG1409@1|root,COG1409@2|Bacteria,3Y3P7@57723|Acidobacteria	57723|Acidobacteria	C	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_4905138_0	1341151.ASZU01000004_gene435	3.934e-112	368.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,27BA5@186824|Thermoactinomycetaceae	91061|Bacilli	S	Aldo/keto reductase family	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_4905138_2	1279038.KB907338_gene1098	8.402e-47	178.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2U9J3@28211|Alphaproteobacteria,2JWZ6@204441|Rhodospirillales	204441|Rhodospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4905138_1	1184267.A11Q_2471	6.006e-75	261.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	CP_1064	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_4910718_8	671143.DAMO_1665	1.232e-27	117.0	COG5501@1|root,COG5501@2|Bacteria	2|Bacteria	-	-	MA20_34470	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
CMS3_k127_4910718_9	1158345.JNLL01000001_gene1473	2.963e-13	77.0	COG2033@1|root,COG2033@2|Bacteria,2G593@200783|Aquificae	200783|Aquificae	C	oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
CMS3_k127_4910718_11	1121481.AUAS01000004_gene1591	1.009e-11	71.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_4910718_3	644282.Deba_1761	3.852e-90	311.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,42NQX@68525|delta/epsilon subdivisions,2WKDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_4910718_2	1238182.C882_2042	1.849e-110	376.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TUAE@28211|Alphaproteobacteria,2JQ8D@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the 5'-nucleotidase family	-	-	-	ko:K17224	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	5_nucleotid_C
CMS3_k127_4910718_10	1380390.JIAT01000010_gene4657	8.865e-13	73.0	COG4454@1|root,COG4454@2|Bacteria,2I7WC@201174|Actinobacteria,4CTCK@84995|Rubrobacteria	84995|Rubrobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_4910718_6	1128421.JAGA01000003_gene3641	2.21e-45	173.0	COG1999@1|root,COG1999@2|Bacteria,2NRAY@2323|unclassified Bacteria	2|Bacteria	S	SCO1/SenC	hyaE	GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277	-	ko:K03619,ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	HyaE,SCO1-SenC
CMS3_k127_4910718_7	309801.trd_0160	2.446e-29	118.0	COG0425@1|root,COG0425@2|Bacteria,2G7DF@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
CMS3_k127_4910718_4	309801.trd_0159	3.986e-70	241.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS3_k127_4910718_5	309801.trd_0158	1.641e-56	199.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
CMS3_k127_4910718_1	882083.SacmaDRAFT_1921	4.262e-116	377.0	COG1150@1|root,COG1150@2|Bacteria,2H2X3@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_8
CMS3_k127_4910718_0	309801.trd_0154	1.5e-174	553.0	COG2048@1|root,COG2048@2|Bacteria	2|Bacteria	C	Heterodisulfide reductase, subunit B	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS3_k127_491316_2	485913.Krac_2174	4.014e-80	274.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_491316_0	324602.Caur_3237	2.116e-115	383.0	COG0834@1|root,COG0834@2|Bacteria,2G7RH@200795|Chloroflexi,376Y9@32061|Chloroflexia	32061|Chloroflexia	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
CMS3_k127_491316_1	926550.CLDAP_08220	7.279e-81	291.0	COG4597@1|root,COG4597@2|Bacteria	2|Bacteria	P	amino acid transport	bgtB	-	-	ko:K09970,ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
CMS3_k127_49134_0	1382306.JNIM01000001_gene3511	3.259e-75	261.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS3_k127_49134_1	269482.Bcep1808_2999	4.269e-05	48.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,1KGPS@119060|Burkholderiaceae	28216|Betaproteobacteria	H	biotin acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_4924062_2	522306.CAP2UW1_2609	1.779e-55	209.0	COG1192@1|root,COG1357@1|root,COG1787@1|root,COG2319@1|root,COG5635@1|root,COG1192@2|Bacteria,COG1357@2|Bacteria,COG1787@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
CMS3_k127_4924062_3	1333523.L593_10660	4.491e-09	63.0	COG3291@1|root,COG3325@1|root,arCOG02546@2157|Archaea,arCOG07840@2157|Archaea,2Y7YU@28890|Euryarchaeota,241E0@183963|Halobacteria	183963|Halobacteria	G	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18,PKD
CMS3_k127_4924062_1	710686.Mycsm_03499	2.405e-56	219.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria,2334C@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4924062_0	1125971.ASJB01000063_gene4120	1.674e-139	479.0	COG5276@1|root,COG5276@2|Bacteria,2I3D6@201174|Actinobacteria,4EDSJ@85010|Pseudonocardiales	201174|Actinobacteria	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS3_k127_4927686_0	485913.Krac_2926	3.125e-107	378.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
CMS3_k127_4927686_1	1123258.AQXZ01000018_gene1065	5.829e-09	70.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4FVWD@85025|Nocardiaceae	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
CMS3_k127_4931855_2	485913.Krac_2635	1.864e-29	127.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS3_k127_4931855_1	326427.Cagg_2931	1.556e-58	217.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
CMS3_k127_4931855_4	1123060.JONP01000062_gene3299	3.402e-14	84.0	COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria	1224|Proteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_4931855_5	1184609.KILIM_069_00290	1.342e-06	55.0	COG1366@1|root,COG1366@2|Bacteria,2HPDK@201174|Actinobacteria,4F787@85018|Dermatophilaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
CMS3_k127_4931855_3	927677.ALVU02000001_gene3917	5.855e-17	86.0	COG2172@1|root,COG2172@2|Bacteria,1G8CF@1117|Cyanobacteria,1H5U9@1142|Synechocystis	1117|Cyanobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
CMS3_k127_4931855_0	316274.Haur_4103	1.059e-121	401.0	2DBC8@1|root,2Z8C9@2|Bacteria,2G9UH@200795|Chloroflexi,3774U@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_493262_3	644966.Tmar_2085	0.0001742	47.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS3_k127_493262_1	489825.LYNGBM3L_14880	5.285e-39	152.0	COG5126@1|root,COG5126@2|Bacteria,1G7DT@1117|Cyanobacteria,1HBQS@1150|Oscillatoriales	1117|Cyanobacteria	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_493262_0	880073.Calab_3175	9.719e-150	484.0	COG1064@1|root,COG1064@2|Bacteria,2NP06@2323|unclassified Bacteria	2|Bacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_493262_2	1463861.JNXE01000012_gene9339	0.000104	48.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_4939455_0	926569.ANT_25010	1.003e-215	677.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
CMS3_k127_4944171_3	324602.Caur_2747	2.553e-21	99.0	COG2852@1|root,COG2852@2|Bacteria,2GAFN@200795|Chloroflexi,375Y8@32061|Chloroflexia	32061|Chloroflexia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4944171_4	861299.J421_3419	2.249e-07	59.0	COG1357@1|root,COG1357@2|Bacteria,1ZTN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_4944171_0	292459.STH849	1.204e-74	260.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_4944171_1	402880.MmarC5_0290	6.594e-52	212.0	COG0840@1|root,arCOG02320@2157|Archaea,2Y7QV@28890|Euryarchaeota,23RVM@183939|Methanococci	183939|Methanococci	T	Integral membrane sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
CMS3_k127_4944171_2	1128421.JAGA01000003_gene3066	9.647e-42	168.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_4951360_0	448385.sce1953	1.518e-19	101.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_4951360_1	1123269.NX02_26940	2.874e-18	97.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,TSP_3
CMS3_k127_4967580_5	266117.Rxyl_0355	1.302e-28	119.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4CQY0@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD dependent oxidoreductase	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
CMS3_k127_4967580_4	383372.Rcas_3508	3.51e-54	200.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
CMS3_k127_4967580_6	450851.PHZ_c2409	4.741e-09	66.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2U28G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
CMS3_k127_4967580_0	383372.Rcas_3519	1.365e-213	673.0	COG0044@1|root,COG0044@2|Bacteria,2G5N4@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
CMS3_k127_4967580_2	1521187.JPIM01000016_gene3684	1.217e-152	491.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,3751U@32061|Chloroflexia	32061|Chloroflexia	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_4967580_3	1462527.CCDM010000001_gene2644	1.356e-62	219.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	-	-	-	-	-	-	-	-	-	-	Aconitase_C
CMS3_k127_4967580_1	383372.Rcas_3516	7.036e-158	505.0	COG0065@1|root,COG0065@2|Bacteria,2G5IZ@200795|Chloroflexi,37560@32061|Chloroflexia	200795|Chloroflexi	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS3_k127_4968827_0	479434.Sthe_2726	8.383e-56	198.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS3_k127_4968827_2	1121889.AUDM01000009_gene1058	9.072e-18	93.0	2C73B@1|root,330Z7@2|Bacteria,4NMGE@976|Bacteroidetes,1I53Q@117743|Flavobacteriia,2NUDC@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4968827_1	1250232.JQNJ01000001_gene1256	1.844e-18	88.0	2ESJ3@1|root,33K3T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_4968827_3	8049.ENSGMOP00000019056	2.308e-07	58.0	28IDA@1|root,2QQPY@2759|Eukaryota,38G8U@33154|Opisthokonta,3BI4P@33208|Metazoa,3CYM8@33213|Bilateria,482YC@7711|Chordata,492TK@7742|Vertebrata,49THZ@7898|Actinopterygii	33208|Metazoa	S	Sacsin-like	-	-	-	ko:K17592	-	-	-	-	ko00000,ko01009	-	-	-	HEPN
CMS3_k127_4974842_1	1380394.JADL01000009_gene3147	1.388e-61	227.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_4974842_3	926690.KE386573_gene3025	4.135e-07	56.0	arCOG04524@1|root,arCOG04524@2157|Archaea,2Y07H@28890|Euryarchaeota,23X54@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4974842_0	1499967.BAYZ01000060_gene6006	1.248e-85	295.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,2NPJ5@2323|unclassified Bacteria	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
CMS3_k127_4974842_2	443143.GM18_0068	2.621e-44	168.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HAMP,HATPase_c,HisKA
CMS3_k127_4974868_3	1128421.JAGA01000003_gene3513	8.384e-28	115.0	COG2378@1|root,COG2378@2|Bacteria,2NPY6@2323|unclassified Bacteria	2|Bacteria	K	WYL domain	yobV5	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
CMS3_k127_4974868_1	1242864.D187_006341	7.073e-45	168.0	2E2RY@1|root,32XUA@2|Bacteria,1N9C1@1224|Proteobacteria,42XP0@68525|delta/epsilon subdivisions,2WT7T@28221|Deltaproteobacteria,2YVJE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS3_k127_4974868_0	479434.Sthe_3085	3.997e-57	211.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,27Y90@189775|Thermomicrobia	189775|Thermomicrobia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS3_k127_4974868_2	926560.KE387023_gene2407	4.047e-41	158.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS3_k127_4975093_2	1121380.JNIW01000006_gene438	2.525e-18	98.0	COG2133@1|root,COG2133@2|Bacteria,1WMHH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	COGs COG2133 Glucose sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_4975093_1	717605.Theco_2504	4.584e-51	187.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,26XEB@186822|Paenibacillaceae	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS3_k127_4975093_0	926550.CLDAP_01250	2.449e-136	438.0	COG1209@1|root,COG1209@2|Bacteria,2G6MR@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_4984955_0	383372.Rcas_1884	2.515e-221	692.0	COG1486@1|root,COG1486@2|Bacteria,2G5M6@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS3_k127_4984955_4	316274.Haur_2674	9.695e-38	157.0	COG1668@1|root,COG1668@2|Bacteria,2G8PJ@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_4984955_3	316274.Haur_2673	1.792e-53	204.0	COG1668@1|root,COG1668@2|Bacteria,2G8PJ@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_4984955_2	316274.Haur_2672	2.179e-100	336.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	ecsA_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_4984955_1	324602.Caur_2007	2.22e-137	448.0	COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi,377MJ@32061|Chloroflexia	32061|Chloroflexia	F	ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
CMS3_k127_4984955_7	1340434.AXVA01000001_gene1114	1.868e-05	49.0	2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli,1ZJ7K@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4984955_6	1123274.KB899431_gene3241	1.355e-05	48.0	2AU0F@1|root,31JKB@2|Bacteria	2|Bacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4984955_5	936155.HFELIS_16070	4.086e-37	141.0	2AICC@1|root,318TJ@2|Bacteria,1Q0XM@1224|Proteobacteria,431XH@68525|delta/epsilon subdivisions,2YSDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4984985_3	1432055.GLUCORHAEAF1_10145	5.434e-69	244.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	MA20_16895	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS3_k127_4984985_2	926569.ANT_07480	3.367e-77	270.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS3_k127_4984985_4	926569.ANT_07490	1.383e-63	229.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS3_k127_4984985_10	1173026.Glo7428_1565	9.793e-26	112.0	COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS3_k127_4984985_6	926560.KE387023_gene3409	1.701e-52	192.0	COG1051@1|root,COG1051@2|Bacteria,1WN9T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
CMS3_k127_4984985_1	388413.ALPR1_05140	1.092e-89	305.0	COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_4984985_8	1239962.C943_02138	5.827e-39	151.0	2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes,47UWC@768503|Cytophagia	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,PAS_8
CMS3_k127_4984985_0	357808.RoseRS_1485	0.0	1302.0	COG0366@1|root,COG0366@2|Bacteria,2G7SV@200795|Chloroflexi	200795|Chloroflexi	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
CMS3_k127_4984985_7	4577.GRMZM2G020775_P01	1.148e-39	157.0	2CJ2D@1|root,2QS3W@2759|Eukaryota,37R7G@33090|Viridiplantae,3GA1W@35493|Streptophyta,3KMYF@4447|Liliopsida,3ICS2@38820|Poales	35493|Streptophyta	S	Sucrase/ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
CMS3_k127_4984985_5	926569.ANT_30510	6.508e-62	223.0	COG3118@1|root,COG3118@2|Bacteria,2G90Y@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Thioredoxin domain	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS3_k127_4984985_9	1174528.JH992898_gene733	1.777e-36	140.0	COG2146@1|root,COG2146@2|Bacteria,1G2KG@1117|Cyanobacteria,1JK9R@1189|Stigonemataceae	1117|Cyanobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
CMS3_k127_4985556_0	1499967.BAYZ01000105_gene3503	1.692e-05	59.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF5011
CMS3_k127_4993720_0	298654.FraEuI1c_2116	1.926e-10	69.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_5009560_1	383372.Rcas_0972	5.238e-66	233.0	COG0474@1|root,COG0474@2|Bacteria,2GAPR@200795|Chloroflexi,376Z7@32061|Chloroflexia	32061|Chloroflexia	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	-	ko:K16905	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	-
CMS3_k127_5009560_2	383372.Rcas_0971	1.014e-45	173.0	COG1668@1|root,COG1668@2|Bacteria,2GBSB@200795|Chloroflexi,376EX@32061|Chloroflexia	32061|Chloroflexia	CP	transmembrane transport	-	-	-	ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_5009560_0	357808.RoseRS_3832	1.264e-112	370.0	COG1131@1|root,COG1131@2|Bacteria,2G6HN@200795|Chloroflexi,3768T@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5010830_0	672.VV93_v1c35450	1.687e-181	576.0	COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria,1XWQ9@135623|Vibrionales	135623|Vibrionales	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M4,Peptidase_M4_C
CMS3_k127_5010830_1	56110.Oscil6304_2573	9.237e-179	614.0	COG1122@1|root,COG2319@1|root,COG1122@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
CMS3_k127_5010830_2	1380386.JIAW01000006_gene1315	5.04e-24	121.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,Guanylate_cyc,NB-ARC
CMS3_k127_5016141_1	1122176.KB903564_gene3177	2.017e-20	104.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	2|Bacteria	M	COG5337 Spore coat assembly protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,LTD
CMS3_k127_5016141_2	1380370.JIBA01000012_gene3521	1.565e-09	70.0	COG2133@1|root,COG3291@1|root,COG3507@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3507@2|Bacteria,2GJFY@201174|Actinobacteria,4FIVV@85021|Intrasporangiaceae	201174|Actinobacteria	G	Carbohydrate binding module (family 6)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,CBM_6,GSDH,PKD
CMS3_k127_5016141_0	926550.CLDAP_01880	5.806e-83	283.0	COG3664@1|root,COG3664@2|Bacteria,2G82D@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5023741_1	316274.Haur_1939	6.634e-29	124.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_5023741_6	240015.ACP_0460	0.0002926	46.0	COG0038@1|root,COG0038@2|Bacteria,3Y7TT@57723|Acidobacteria,2JMYW@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
CMS3_k127_5023741_3	765420.OSCT_2895	1.064e-22	104.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
CMS3_k127_5023741_0	926550.CLDAP_19470	3.162e-107	383.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_5023741_4	204669.Acid345_4587	1.014e-13	78.0	2E32R@1|root,32Y2Y@2|Bacteria,3Y5RV@57723|Acidobacteria,2JNI4@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5025253_1	926569.ANT_13340	1.694e-99	338.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS3_k127_5025253_3	926569.ANT_12940	1.574e-71	256.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS3_k127_5025253_2	926569.ANT_12940	3.974e-76	273.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS3_k127_5025253_4	1232410.KI421428_gene1022	6.415e-54	199.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_5025253_0	105422.BBPM01000102_gene5262	2.752e-138	470.0	COG3055@1|root,COG3405@1|root,COG3055@2|Bacteria,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	ASH
CMS3_k127_5025253_5	1278073.MYSTI_03344	3.67e-13	83.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria,1NNV4@1224|Proteobacteria,42Q3S@68525|delta/epsilon subdivisions,2WMM2@28221|Deltaproteobacteria,2Z1Q8@29|Myxococcales	28221|Deltaproteobacteria	E	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5026610_2	1279009.ADICEAN_03023	5.38e-115	404.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,47NP4@768503|Cytophagia	976|Bacteroidetes	S	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
CMS3_k127_5026610_6	1313421.JHBV01000041_gene3557	4.126e-07	64.0	COG1572@1|root,COG1649@1|root,COG1572@2|Bacteria,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23	ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K18197	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	GH33,GH66,PL11	-	DUF3367,DUF5122,GHL10,Glyco_hydro_20b,NAGidase
CMS3_k127_5026610_0	485913.Krac_3074	5.066e-144	466.0	COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_5026610_4	1183438.GKIL_1369	3.638e-87	314.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS3_k127_5026610_3	426117.M446_1000	9.051e-104	353.0	COG0654@1|root,COG0654@2|Bacteria,1QNRY@1224|Proteobacteria,2TR9Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_5026610_1	926550.CLDAP_19470	1.687e-135	477.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_5026610_5	32057.KB217478_gene826	2.832e-43	175.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.4.16.4,3.5.2.6	ko:K01286,ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
CMS3_k127_5028490_0	502025.Hoch_5031	4.925e-166	562.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,438DH@68525|delta/epsilon subdivisions,2WXQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos
CMS3_k127_5042858_4	156889.Mmc1_1409	3.35e-12	67.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0471 Di- and tricarboxylate transporters	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS3_k127_5042858_3	1205680.CAKO01000032_gene2111	5.416e-34	141.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,GerE,Guanylate_cyc,Hydrolase_4,Trans_reg_C
CMS3_k127_5042858_1	926550.CLDAP_13310	1.403e-76	275.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS3_k127_5042858_0	316274.Haur_2227	3.064e-179	572.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi,3763M@32061|Chloroflexia	32061|Chloroflexia	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_5042858_2	1395571.TMS3_0113110	2.953e-37	144.0	2C5YD@1|root,342V0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_505021_0	926569.ANT_16350	4.332e-158	507.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS3_k127_505021_1	1499967.BAYZ01000136_gene51	5.695e-73	267.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG4916@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,COG4916@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TIR_2,TPR_12,TPR_7
CMS3_k127_505030_3	7237.FBpp0286894	1.564e-29	130.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa,3CSKJ@33213|Bilateria,41YHD@6656|Arthropoda,3SIXR@50557|Insecta,4519D@7147|Diptera,45PZ1@7214|Drosophilidae	33208|Metazoa	M	Pectinacetylesterase	NOTUM	GO:0000902,GO:0000904,GO:0003002,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008045,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009605,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009952,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0012505,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019538,GO:0019637,GO:0021532,GO:0021915,GO:0022008,GO:0023051,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030163,GO:0030178,GO:0030182,GO:0031175,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0035220,GO:0035222,GO:0035295,GO:0035601,GO:0036211,GO:0040011,GO:0042157,GO:0042159,GO:0042221,GO:0042330,GO:0042578,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046486,GO:0046488,GO:0048070,GO:0048073,GO:0048076,GO:0048190,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0052689,GO:0060429,GO:0060828,GO:0061564,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0090090,GO:0097485,GO:0098732,GO:0120036,GO:0120039,GO:1901135,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1990697,GO:1990699	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_505030_0	926569.ANT_26570	1.717e-94	321.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_505030_1	1304865.JAGF01000001_gene3276	8.018e-65	231.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4F116@85016|Cellulomonadaceae	201174|Actinobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_505030_2	1122201.AUAZ01000005_gene620	2.846e-34	142.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,1S5NV@1236|Gammaproteobacteria,468YV@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Cytochrome c biogenesis protein	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS3_k127_505030_5	1236902.ANAS01000006_gene5168	1.764e-19	97.0	2ACPI@1|root,312A5@2|Bacteria,2I99C@201174|Actinobacteria,4EIMX@85012|Streptosporangiales	201174|Actinobacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
CMS3_k127_505030_4	1128421.JAGA01000003_gene3576	3.025e-28	123.0	COG0526@1|root,COG0526@2|Bacteria,2NPYK@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin-like	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ,Redoxin,Thioredoxin_8
CMS3_k127_5058096_2	7460.GB49624-PA	3.455e-10	64.0	KOG4268@1|root,KOG4268@2759|Eukaryota,39V02@33154|Opisthokonta,3BJQ9@33208|Metazoa,3CTNN@33213|Bilateria,41YTI@6656|Arthropoda,3SM1N@50557|Insecta,46I7Z@7399|Hymenoptera	33208|Metazoa	S	Acid phosphatase homologues	PPAPDC2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006694,GO:0006695,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016125,GO:0016126,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030258,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046165,GO:0046839,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653	-	ko:K17981	-	-	-	-	ko00000,ko03029	-	-	-	PAP2
CMS3_k127_5058096_0	926569.ANT_06880	1.781e-84	307.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
CMS3_k127_5058096_1	1047013.AQSP01000140_gene2535	8.957e-72	255.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_5058931_2	56110.Oscil6304_2141	6.863e-75	257.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1FZXP@1117|Cyanobacteria,1H9FJ@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
CMS3_k127_5058931_0	530564.Psta_4424	5.225e-177	599.0	COG0457@1|root,COG2956@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,2IXCM@203682|Planctomycetes	203682|Planctomycetes	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
CMS3_k127_5058931_5	1279009.ADICEAN_04044	3.488e-28	130.0	COG0500@1|root,COG2226@2|Bacteria,4NE1M@976|Bacteroidetes,47JDG@768503|Cytophagia	976|Bacteroidetes	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS3_k127_5058931_1	1336243.JAEA01000014_gene3655	2.482e-156	500.0	COG2141@1|root,COG2141@2|Bacteria,1MUTJ@1224|Proteobacteria,2TTZI@28211|Alphaproteobacteria,1JU1Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5058931_3	357808.RoseRS_4583	2.292e-70	241.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_5059882_0	926550.CLDAP_04280	1.286e-29	128.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
CMS3_k127_5059882_1	317936.Nos7107_1720	9.707e-07	61.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HU5N@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS3_k127_5069635_0	446469.Sked_13890	7.93e-116	385.0	COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria	201174|Actinobacteria	G	alpha amylase, catalytic	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
CMS3_k127_5069635_1	358396.C445_15631	3.729e-41	155.0	COG2746@1|root,arCOG06298@2157|Archaea,2XSY6@28890|Euryarchaeota,23TW3@183963|Halobacteria	183963|Halobacteria	V	COG2746 Aminoglycoside N3'-acetyltransferase	aacC	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
CMS3_k127_5072278_0	1242864.D187_000827	4.498e-125	422.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2X5HN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_5078153_0	1304284.L21TH_1745	2.378e-79	272.0	COG0189@1|root,COG0189@2|Bacteria,1TWCJ@1239|Firmicutes,24BGF@186801|Clostridia,36HBP@31979|Clostridiaceae	186801|Clostridia	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
CMS3_k127_5078153_1	383372.Rcas_2261	1.006e-53	206.0	COG0438@1|root,COG0438@2|Bacteria,2G82G@200795|Chloroflexi,375AN@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
CMS3_k127_5080051_3	926550.CLDAP_36710	8.732e-26	110.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS3_k127_5080051_2	485913.Krac_0867	1.097e-29	121.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5080051_5	861299.J421_4028	7.256e-13	72.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5080051_0	118168.MC7420_1489	2.166e-100	335.0	COG0714@1|root,COG0714@2|Bacteria,1G09T@1117|Cyanobacteria,1H9U7@1150|Oscillatoriales	1117|Cyanobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS3_k127_5080051_1	118168.MC7420_1469	2.427e-55	203.0	COG3825@1|root,COG3825@2|Bacteria,1G1TM@1117|Cyanobacteria,1HBDN@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_5087701_4	926550.CLDAP_31600	1.192e-33	133.0	COG1063@1|root,COG1063@2|Bacteria,2G6FN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
CMS3_k127_5087701_0	1089550.ATTH01000001_gene798	3.537e-130	431.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,4PIWG@976|Bacteroidetes,1FK0G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydro2,RibD_C
CMS3_k127_5087701_2	1242864.D187_001138	2.56e-55	206.0	COG3291@1|root,COG3291@2|Bacteria,1NE5Q@1224|Proteobacteria,433YB@68525|delta/epsilon subdivisions,2X423@28221|Deltaproteobacteria,2YY0M@29|Myxococcales	28221|Deltaproteobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
CMS3_k127_5087701_1	926569.ANT_13490	1.309e-126	421.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS3_k127_5087701_3	357808.RoseRS_1251	6.67e-45	181.0	COG0793@1|root,COG0793@2|Bacteria,2GBRW@200795|Chloroflexi,376BR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41,Tricorn_C1
CMS3_k127_5087701_5	316274.Haur_1183	1.839e-08	62.0	COG2866@1|root,COG2866@2|Bacteria,2G7U3@200795|Chloroflexi	200795|Chloroflexi	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_5095197_0	518766.Rmar_2766	0.0	1230.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_5095197_4	1382356.JQMP01000004_gene227	2.917e-72	246.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_5095197_3	479434.Sthe_2778	7.998e-96	323.0	COG1319@1|root,COG1319@2|Bacteria,2G84Z@200795|Chloroflexi,27Z3G@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_5095197_5	324602.Caur_3470	2.234e-39	155.0	COG3170@1|root,COG3427@1|root,COG3170@2|Bacteria,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS3_k127_5095197_2	479434.Sthe_1402	1.056e-99	340.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,27XNE@189775|Thermomicrobia	189775|Thermomicrobia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_5095197_1	309801.trd_1209	4.913e-108	357.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,27Y33@189775|Thermomicrobia	189775|Thermomicrobia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS3_k127_5100486_1	926569.ANT_04370	1.423e-103	343.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS3_k127_5100486_0	926569.ANT_18360	1.794e-132	428.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_5100486_2	357808.RoseRS_3160	8.642e-101	342.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,374YS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_5108568_0	926569.ANT_11200	7.45e-93	321.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS3_k127_5108568_1	1120949.KB903317_gene1760	1.196e-06	59.0	COG1361@1|root,COG1361@2|Bacteria,2I6N1@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_5117079_6	1123371.ATXH01000027_gene159	8.515e-23	98.0	COG0211@1|root,COG0211@2|Bacteria,2GI1D@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS3_k127_5117079_5	926569.ANT_25140	2.078e-34	137.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS3_k127_5117079_0	1128421.JAGA01000003_gene2741	3.707e-81	274.0	COG1435@1|root,COG1435@2|Bacteria,2NP88@2323|unclassified Bacteria	2|Bacteria	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iLJ478.TM0401	TK
CMS3_k127_5117079_3	765420.OSCT_0959	1.571e-64	227.0	COG0634@1|root,COG0634@2|Bacteria,2GAS7@200795|Chloroflexi,37753@32061|Chloroflexia	32061|Chloroflexia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS3_k127_5117079_2	1128421.JAGA01000003_gene3000	5.853e-75	273.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974,ko:K07276,ko:K19545	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko01504,ko03016,ko03019	-	-	-	Aminoglyc_resit,HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
CMS3_k127_5117079_4	1463926.JOCA01000026_gene6744	1.916e-60	224.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria	201174|Actinobacteria	CG	Glycosyltransferase, MGT family	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
CMS3_k127_5117079_1	867845.KI911784_gene3657	2.344e-76	261.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS3_k127_5117079_8	485913.Krac_7332	0.0008495	51.0	COG0515@1|root,COG0515@2|Bacteria	485913.Krac_7332|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5119074_1	378806.STAUR_6762	3.962e-21	96.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,2YXUA@29|Myxococcales	28221|Deltaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS3_k127_5119074_2	391625.PPSIR1_31123	2.909e-07	62.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase,TIR_2,WD40
CMS3_k127_5119074_0	1499967.BAYZ01000102_gene3557	1.314e-31	130.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS3_k127_5120398_0	1122176.KB903548_gene1179	1.135e-92	334.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4NUFW@976|Bacteroidetes,1IZ0P@117747|Sphingobacteriia	976|Bacteroidetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
CMS3_k127_5122146_0	66377.JOBH01000018_gene2478	6.443e-35	153.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
CMS3_k127_5122146_1	1082933.MEA186_23816	7.282e-16	83.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.1.1.137,2.3.1.1	ko:K00537,ko:K00619,ko:K07755	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
CMS3_k127_5136663_0	675635.Psed_4920	4.567e-154	499.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS3_k127_5137327_1	1144275.COCOR_03695	1.813e-53	214.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5137327_2	316274.Haur_3891	4.809e-37	146.0	COG1309@1|root,COG1309@2|Bacteria,2G995@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5137327_0	102129.Lepto7375DRAFT_2355	3.294e-55	201.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
CMS3_k127_5140208_0	292459.STH2641	1.634e-82	283.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
CMS3_k127_5140208_1	751944.HALDL1_07325	7.803e-60	218.0	COG2301@1|root,arCOG00760@2157|Archaea,2XUK3@28890|Euryarchaeota,23S1V@183963|Halobacteria	183963|Halobacteria	G	COG2301 Citrate lyase beta subunit	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS3_k127_514282_0	1128421.JAGA01000002_gene342	4.54e-163	527.0	COG3845@1|root,COG3845@2|Bacteria	2|Bacteria	P	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
CMS3_k127_514282_1	479434.Sthe_1369	2.798e-46	174.0	COG1598@1|root,COG2318@1|root,COG1598@2|Bacteria,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
CMS3_k127_5144594_0	161156.JQKW01000008_gene525	1.067e-112	374.0	COG0216@1|root,COG0216@2|Bacteria,2GHCQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_5144594_1	926550.CLDAP_10960	6.199e-47	173.0	COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_5147135_1	909663.KI867150_gene2380	4.752e-71	248.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CMS3_k127_5147135_0	471852.Tcur_4825	3.928e-95	318.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_25
CMS3_k127_5151929_2	298655.KI912266_gene3738	4.803e-31	143.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EVA2@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
CMS3_k127_5151929_0	485913.Krac_6991	5.448e-132	462.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_5151929_1	1385519.N801_16570	9.827e-77	263.0	COG2197@1|root,COG2197@2|Bacteria,2IFE7@201174|Actinobacteria,4FGY2@85021|Intrasporangiaceae	201174|Actinobacteria	K	regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_5153120_5	311424.DhcVS_182	1.026e-74	257.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,34CK0@301297|Dehalococcoidia	301297|Dehalococcoidia	J	leucyl-tRNA aminoacylation	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
CMS3_k127_5153120_2	479434.Sthe_2131	1.363e-130	430.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27XZ4@189775|Thermomicrobia	200795|Chloroflexi	E	Cys/Met metabolism PLP-dependent enzyme	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5153120_3	926550.CLDAP_26430	9.017e-93	311.0	COG0388@1|root,COG0388@2|Bacteria,2G6KM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K11206,ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_5153120_9	1353528.DT23_03955	3.269e-44	172.0	COG2931@1|root,COG3170@1|root,COG2931@2|Bacteria,COG3170@2|Bacteria,1RES4@1224|Proteobacteria,2UNPR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Hint_2
CMS3_k127_5153120_10	867845.KI911784_gene1523	6.604e-34	136.0	COG1476@1|root,COG1476@2|Bacteria,2GB72@200795|Chloroflexi,377H5@32061|Chloroflexia	32061|Chloroflexia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5153120_1	1128421.JAGA01000003_gene3003	3.803e-161	516.0	COG1089@1|root,COG1089@2|Bacteria,2NNM2@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_5153120_4	42256.RradSPS_0598	1.2e-85	291.0	COG2514@1|root,COG2514@2|Bacteria,2GN1X@201174|Actinobacteria,4CSUF@84995|Rubrobacteria	84995|Rubrobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS3_k127_5153120_8	1382356.JQMP01000003_gene1954	4.867e-45	170.0	COG0431@1|root,COG0431@2|Bacteria,2GBES@200795|Chloroflexi,27Z6R@189775|Thermomicrobia	189775|Thermomicrobia	S	NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
CMS3_k127_5153120_12	1242864.D187_009937	7.197e-26	117.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42T87@68525|delta/epsilon subdivisions,2WP52@28221|Deltaproteobacteria,2YURQ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS3_k127_5153120_7	326427.Cagg_1565	4.136e-68	237.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi,376J9@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_5153120_11	266117.Rxyl_1049	1.144e-27	123.0	COG1309@1|root,COG1309@2|Bacteria,2GRIJ@201174|Actinobacteria,4CQMX@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5153120_13	765420.OSCT_1616	1.325e-16	94.0	COG3693@1|root,COG3693@2|Bacteria,2GBK8@200795|Chloroflexi,37819@32061|Chloroflexia	32061|Chloroflexia	M	Flagellar filament outer layer protein Flaa	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5153120_14	1123277.KB893181_gene2329	4.311e-12	79.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47NBF@768503|Cytophagia	976|Bacteroidetes	S	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_5153120_6	926550.CLDAP_27070	4.467e-70	249.0	2BWNB@1|root,32WFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5153120_0	926550.CLDAP_27080	4.827e-178	566.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	2|Bacteria	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	patA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K05830,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R01155,R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426	Aminotran_3
CMS3_k127_5153120_15	401053.AciPR4_1956	9.769e-09	67.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5162097_0	1353531.AZNX01000016_gene4351	2.355e-116	386.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,4BBWY@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HAMP
CMS3_k127_5162097_1	357808.RoseRS_3830	2.749e-32	135.0	COG0474@1|root,COG0474@2|Bacteria,2GAPR@200795|Chloroflexi,376Z7@32061|Chloroflexia	32061|Chloroflexia	P	ATPase, P-type transporting, HAD superfamily, subfamily IC	-	-	-	ko:K16905	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	-
CMS3_k127_5162097_2	304371.MCP_1634	9.84e-25	111.0	arCOG05875@1|root,arCOG05875@2157|Archaea,2XWFY@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_5163241_12	1499967.BAYZ01000089_gene5053	1.255e-70	250.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_5163241_20	1227349.C170_02029	1.209e-24	113.0	COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HJDU@91061|Bacilli,270WR@186822|Paenibacillaceae	91061|Bacilli	S	SNARE associated Golgi protein	yjbF	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_5163241_22	1123242.JH636435_gene1177	2.217e-21	98.0	COG1917@1|root,COG1917@2|Bacteria,2J134@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_5163241_0	290397.Adeh_1447	1.243e-238	763.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2YX1W@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
CMS3_k127_5163241_17	383372.Rcas_0716	7.534e-54	200.0	2CDYB@1|root,33ZY4@2|Bacteria,2GBTK@200795|Chloroflexi,3776Z@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5163241_2	1449080.JQMV01000003_gene1597	3.34e-160	534.0	COG1874@1|root,COG1874@2|Bacteria,1WJAT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Beta-galactosidase trimerisation domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
CMS3_k127_5163241_5	324602.Caur_3818	7.781e-135	445.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi,3751K@32061|Chloroflexia	32061|Chloroflexia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
CMS3_k127_5163241_10	357808.RoseRS_2752	6.377e-93	311.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi,376K4@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the HAD-like hydrolase superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_5163241_13	867845.KI911784_gene3257	6.995e-67	243.0	COG0395@1|root,COG0395@2|Bacteria,2G6JM@200795|Chloroflexi,37760@32061|Chloroflexia	32061|Chloroflexia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS3_k127_5163241_14	1219084.AP014508_gene907	9.924e-62	234.0	COG1175@1|root,COG1175@2|Bacteria,2GC8J@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K17242	ko02010,map02010	M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.39	-	-	BPD_transp_1
CMS3_k127_5163241_8	1128421.JAGA01000003_gene3075	5.818e-103	352.0	COG1653@1|root,COG1653@2|Bacteria,2NRKY@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS3_k127_5163241_11	926569.ANT_04610	3.181e-90	308.0	COG1609@1|root,COG1609@2|Bacteria,2G855@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_5163241_1	1242864.D187_001830	3.019e-160	547.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS3_k127_5163241_26	313606.M23134_06028	2.654e-10	71.0	297TZ@1|root,2ZV0N@2|Bacteria,4P8WH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5163241_9	1382306.JNIM01000001_gene3652	7.54e-103	342.0	COG0179@1|root,COG0179@2|Bacteria,2G6HH@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS3_k127_5163241_19	309801.trd_1809	2.051e-38	156.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,27Y8A@189775|Thermomicrobia	189775|Thermomicrobia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5163241_16	926569.ANT_04520	3.902e-54	196.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS3_k127_5163241_3	926569.ANT_14860	5.305e-156	504.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
CMS3_k127_5163241_7	926569.ANT_04510	2.492e-110	362.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_5163241_4	926550.CLDAP_25810	4.691e-144	467.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS3_k127_5163241_23	357808.RoseRS_1371	3.122e-21	96.0	COG1146@1|root,COG1146@2|Bacteria,2G7ES@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
CMS3_k127_5163241_15	926569.ANT_18260	1.125e-58	209.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	GAF_2,Pribosyltran
CMS3_k127_5163241_18	926569.ANT_18270	4.687e-42	157.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
CMS3_k127_5163241_21	1121382.JQKG01000003_gene4121	1.591e-22	102.0	COG0517@1|root,COG0517@2|Bacteria,1WMQJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_5163241_6	518766.Rmar_2417	3.866e-122	401.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1FJRD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
CMS3_k127_5166299_3	1278073.MYSTI_05406	7.204e-110	367.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS3_k127_5166299_9	1009370.ALO_09559	8.61e-15	83.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4H4BG@909932|Negativicutes	909932|Negativicutes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_5166299_4	926569.ANT_22490	3.076e-50	188.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS3_k127_5166299_10	1410628.JNKS01000011_gene2597	0.0006926	49.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,27JQK@186928|unclassified Lachnospiraceae	186801|Clostridia	L	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
CMS3_k127_5166299_8	926569.ANT_11010	7.77e-20	104.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5166299_7	1122613.ATUP01000002_gene2434	3.305e-21	103.0	COG3591@1|root,COG3591@2|Bacteria,1NXYY@1224|Proteobacteria,2UTKV@28211|Alphaproteobacteria,43XYM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5166299_5	926569.ANT_29880	1.323e-34	139.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_5166299_1	926569.ANT_29890	5.249e-194	617.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_5166299_2	745776.DGo_CA2326	2.815e-173	563.0	COG1226@1|root,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	dMI1	-	3.1.4.46	ko:K01126,ko:K10716	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Castor_Poll_mid,TrkA_N
CMS3_k127_5166299_0	56110.Oscil6304_5340	0.0	1179.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1H81U@1150|Oscillatoriales	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CMS3_k127_5172472_2	1117315.AHCA01000005_gene1082	3.954e-07	53.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,2Q24K@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Uncharacterised protein family UPF0047	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_5172472_1	46234.ANA_C20072	6.143e-31	128.0	COG2852@1|root,COG2852@2|Bacteria,1GNS3@1117|Cyanobacteria,1HP42@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
CMS3_k127_5172472_0	926550.CLDAP_09290	2.087e-124	410.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi	200795|Chloroflexi	E	aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5174018_1	926550.CLDAP_27920	1.075e-20	94.0	COG1858@1|root,COG2133@1|root,COG1858@2|Bacteria,COG2133@2|Bacteria,2G989@200795|Chloroflexi	200795|Chloroflexi	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_5174018_0	1128421.JAGA01000003_gene3537	2.746e-82	280.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_517579_2	1128421.JAGA01000002_gene780	1.758e-70	251.0	COG1577@1|root,COG1577@2|Bacteria,2NR5A@2323|unclassified Bacteria	2|Bacteria	I	GHMP kinases C terminal	mvk	-	1.1.1.88,2.3.3.10,2.7.1.36	ko:K00054,ko:K00869,ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146	M00088,M00095	R01978,R02081,R02245	RC00002,RC00004,RC00017,RC00503,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_517579_1	926569.ANT_15930	2.557e-93	315.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS3_k127_517579_0	1341646.CBMO010000161_gene4356	4.097e-100	332.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,232A4@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA15	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_5178328_9	412597.AEPN01000008_gene2184	4.219e-27	115.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_5178328_7	1382306.JNIM01000001_gene1022	1.27e-52	192.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_5178328_1	1125863.JAFN01000001_gene1218	1.812e-239	763.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_5178328_6	1333856.L686_22615	9.673e-79	278.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1Z1QR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5178328_10	1293054.HSACCH_01940	1.097e-20	97.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,24HPI@186801|Clostridia	186801|Clostridia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	4.4.1.5,5.1.99.1	ko:K01759,ko:K05606	ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02530,R02765,R09979	RC00004,RC00740,RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS3_k127_5178328_3	1125863.JAFN01000001_gene1231	5.225e-142	462.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,42QAD@68525|delta/epsilon subdivisions,2WK5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_5178328_5	706587.Desti_1830	2.093e-108	363.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42Y7P@68525|delta/epsilon subdivisions,2WUJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5178328_8	1125863.JAFN01000001_gene1225	2.97e-42	159.0	COG2185@1|root,COG2185@2|Bacteria,1N56M@1224|Proteobacteria,42UGU@68525|delta/epsilon subdivisions,2WQDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CMS3_k127_5178328_2	589924.Ferp_2331	5.922e-215	679.0	COG1884@1|root,arCOG04232@2157|Archaea,2XU3F@28890|Euryarchaeota,245QJ@183980|Archaeoglobi	2157|Archaea	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS3_k127_5178328_0	706587.Desti_1834	3.166e-294	917.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2MQZU@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS3_k127_5178328_4	706587.Desti_1835	1.623e-118	386.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,2MS4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS3_k127_5181079_2	335543.Sfum_1389	1.023e-65	232.0	COG1811@1|root,COG1811@2|Bacteria,1MX1D@1224|Proteobacteria,42S9G@68525|delta/epsilon subdivisions,2WNUQ@28221|Deltaproteobacteria,2MQH1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
CMS3_k127_5181079_4	65093.PCC7418_0145	0.0002915	49.0	2ETGP@1|root,33M0J@2|Bacteria,1GAIU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5181079_3	243164.DET0359	1.724e-12	76.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi,34D9U@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS3_k127_5181079_1	926550.CLDAP_31480	9.135e-83	287.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
CMS3_k127_5181079_0	926569.ANT_22600	2.259e-94	321.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
CMS3_k127_5181181_1	882082.SaccyDRAFT_4472	1.367e-29	123.0	COG1309@1|root,COG1309@2|Bacteria,2HR0A@201174|Actinobacteria,4E3IU@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K18939	-	M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_13,TetR_N
CMS3_k127_5181181_0	1429916.X566_18290	8.445e-65	235.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,2U1QB@28211|Alphaproteobacteria,3JT7Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
CMS3_k127_5196525_1	1121448.DGI_4033	1.991e-39	159.0	COG2244@1|root,COG2244@2|Bacteria,1PGP1@1224|Proteobacteria,43491@68525|delta/epsilon subdivisions,2X1JT@28221|Deltaproteobacteria,2MF7P@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5196525_2	395961.Cyan7425_0636	2.065e-39	158.0	2DPRD@1|root,33332@2|Bacteria,1GB6G@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_5196525_0	765420.OSCT_2114	1.076e-108	392.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_5203963_8	1177928.TH2_17634	4.349e-31	130.0	COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria,2U95Y@28211|Alphaproteobacteria,2JTR2@204441|Rhodospirillales	204441|Rhodospirillales	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_5203963_2	525904.Tter_0301	3e-43	178.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
CMS3_k127_5203963_1	1128421.JAGA01000002_gene1308	4.504e-59	213.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_5203963_4	926550.CLDAP_14450	1.365e-42	165.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
CMS3_k127_5203963_10	767817.Desgi_0800	6.48e-10	65.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_5203963_9	264732.Moth_1992	1.74e-21	102.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5203963_12	365044.Pnap_1257	4.871e-06	58.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5203963_6	456442.Mboo_0073	1.605e-32	141.0	COG0785@1|root,arCOG02400@2157|Archaea,2Y0J2@28890|Euryarchaeota,2NBK2@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
CMS3_k127_5203963_11	1227739.Hsw_2897	2.444e-08	65.0	COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47QE9@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS3_k127_5203963_3	926550.CLDAP_40040	1.338e-42	164.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
CMS3_k127_5203963_0	926550.CLDAP_40030	8.94e-167	547.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS3_k127_5203963_5	926569.ANT_19460	3.854e-36	142.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS3_k127_5203963_13	381666.H16_B2160	1.096e-05	55.0	COG2114@1|root,COG3813@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3813@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_4
CMS3_k127_5203963_7	926569.ANT_19420	9.386e-32	139.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
CMS3_k127_5205916_1	945713.IALB_0216	1.877e-26	117.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5205916_0	926569.ANT_30520	3.773e-301	964.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_N,Big_5,Malt_amylase_C
CMS3_k127_5210847_1	1121396.KB892900_gene2129	1.278e-32	146.0	COG1657@1|root,COG2374@1|root,COG2931@1|root,COG3291@1|root,COG4733@1|root,COG4932@1|root,COG5306@1|root,COG1657@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria,COG5306@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
CMS3_k127_5210847_0	644282.Deba_0431	6.619e-178	573.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS3_k127_5210847_2	590998.Celf_0464	2.044e-30	124.0	COG1694@1|root,COG1694@2|Bacteria,2IQFH@201174|Actinobacteria	201174|Actinobacteria	S	Mazg nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS3_k127_5210847_3	1121878.AUGL01000014_gene1673	8.007e-11	64.0	COG0697@1|root,COG0697@2|Bacteria,1QSKQ@1224|Proteobacteria,1RYG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_5212748_2	1121930.AQXG01000004_gene2940	1.187e-107	352.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1INP6@117747|Sphingobacteriia	976|Bacteroidetes	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS3_k127_5212748_0	401526.TcarDRAFT_0353	5.025e-136	443.0	COG2515@1|root,COG2515@2|Bacteria,1UDCW@1239|Firmicutes,4H3NQ@909932|Negativicutes	909932|Negativicutes	E	D-cysteine desulfhydrase	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
CMS3_k127_5212748_4	709986.Deima_0373	2.202e-61	220.0	COG1794@1|root,COG1794@2|Bacteria	2|Bacteria	M	racemase activity, acting on amino acids and derivatives	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
CMS3_k127_5212748_3	582744.Msip34_1961	4.93e-91	309.0	COG3621@1|root,COG3621@2|Bacteria,1RDY7@1224|Proteobacteria	1224|Proteobacteria	S	COG3621 Patatin	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_5212748_1	316274.Haur_2806	1.329e-123	412.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,37674@32061|Chloroflexia	32061|Chloroflexia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_5217795_1	1121271.AUCM01000016_gene2636	7.599e-31	128.0	COG2010@1|root,COG2010@2|Bacteria,1RGXM@1224|Proteobacteria,2U95Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_5217795_2	1123248.KB893328_gene919	8.326e-12	74.0	COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_5217795_0	926560.KE387023_gene2012	9.996e-58	209.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_5219119_1	595460.RRSWK_02658	4.169e-98	334.0	COG1134@1|root,COG1134@2|Bacteria,2IX6N@203682|Planctomycetes	203682|Planctomycetes	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_5219119_2	207559.Dde_0841	1.695e-97	326.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42SZT@68525|delta/epsilon subdivisions,2WIVA@28221|Deltaproteobacteria,2MC09@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_5219119_0	926569.ANT_29360	1.891e-135	446.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_5219119_3	471856.Jden_1266	1.838e-20	104.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	xerD	GO:0008150,GO:0040007	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_5220681_1	1174528.JH992893_gene5848	2.81e-52	190.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	mcyA	-	-	ko:K16130	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,McyA_C,Methyltransf_12,PP-binding
CMS3_k127_5220681_2	1121406.JAEX01000016_gene1873	3.619e-22	108.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_3_5,Polysacc_deac_1
CMS3_k127_5220681_0	272134.KB731325_gene578	4.833e-313	991.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HEH0@1150|Oscillatoriales	1117|Cyanobacteria	Q	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_5221139_7	926550.CLDAP_32740	4.893e-133	430.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_5221139_3	926550.CLDAP_32730	6.636e-207	654.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS3_k127_5221139_5	28258.KP05_09440	1.694e-144	471.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,1RNY9@1236|Gammaproteobacteria,1XN0B@135619|Oceanospirillales	135619|Oceanospirillales	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_5221139_12	392500.Swoo_1352	1.34e-65	235.0	COG3221@1|root,COG3221@2|Bacteria,1PFPM@1224|Proteobacteria,1SXBG@1236|Gammaproteobacteria,2QDCZ@267890|Shewanellaceae	1236|Gammaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_5221139_2	1380394.JADL01000003_gene4950	8.306e-224	700.0	COG0665@1|root,COG0665@2|Bacteria,1R40G@1224|Proteobacteria,2U1VU@28211|Alphaproteobacteria,2JRIU@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_5221139_6	1380391.JIAS01000011_gene4754	4.952e-144	472.0	COG5598@1|root,COG5598@2|Bacteria,1MX73@1224|Proteobacteria,2TS1M@28211|Alphaproteobacteria,2JVS6@204441|Rhodospirillales	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
CMS3_k127_5221139_20	5786.XP_003287580.1	4.3e-05	53.0	2958Q@1|root,2RC6M@2759|Eukaryota,3XAGV@554915|Amoebozoa	554915|Amoebozoa	S	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
CMS3_k127_5221139_14	43354.JOIJ01000027_gene3357	4.835e-47	179.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,4E0VJ@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	allR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS3_k127_5221139_4	266117.Rxyl_1559	2.375e-182	578.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,4CTF3@84995|Rubrobacteria	84995|Rubrobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_5221139_21	935840.JAEQ01000010_gene1581	0.0001228	54.0	COG3799@1|root,COG3799@2|Bacteria,1MW90@1224|Proteobacteria,2TU5V@28211|Alphaproteobacteria,43NBG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Methylaspartate ammonia-lyase C-terminus	-	-	4.3.1.2	ko:K04835	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R03696	RC00979	ko00000,ko00001,ko00002,ko01000	-	-	-	MAAL_C,MAAL_N
CMS3_k127_5221139_17	1410609.JHVB01000005_gene1266	1.506e-32	135.0	COG0517@1|root,COG0517@2|Bacteria,2J6JU@203691|Spirochaetes	203691|Spirochaetes	S	CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
CMS3_k127_5221139_0	926550.CLDAP_32790	3.277e-299	932.0	COG0444@1|root,COG4608@1|root,COG0444@2|Bacteria,COG4608@2|Bacteria,2GBKB@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS3_k127_5221139_9	926550.CLDAP_32780	2.488e-112	377.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_5221139_8	1265505.ATUG01000002_gene1456	2.257e-121	404.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WKTS@28221|Deltaproteobacteria,2MJEJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_5221139_1	926550.CLDAP_32760	1.108e-232	732.0	COG0747@1|root,COG0747@2|Bacteria,2G8RA@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_5221139_19	926569.ANT_19170	2.966e-05	56.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	ko:K04066,ko:K07037,ko:K17266	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400,ko04147	-	-	-	Band_7
CMS3_k127_5221139_11	316274.Haur_3467	1.899e-67	240.0	COG0524@1|root,COG0524@2|Bacteria,2G8C3@200795|Chloroflexi,376T5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_5221139_16	765420.OSCT_1767	1.985e-36	148.0	COG0170@1|root,COG0170@2|Bacteria,2GBR5@200795|Chloroflexi,3767Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM phosphatidate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5221139_15	926569.ANT_19610	1.688e-37	149.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_5221139_10	109760.SPPG_07276T0	3.023e-80	280.0	COG1078@1|root,2RY2F@2759|Eukaryota,38M1J@33154|Opisthokonta,3P19J@4751|Fungi	4751|Fungi	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_5221139_13	309807.SRU_0260	9.327e-61	230.0	COG0815@1|root,COG0815@2|Bacteria,4NMJK@976|Bacteroidetes	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_5225010_0	452637.Oter_2033	4.716e-48	192.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
CMS3_k127_5225010_1	350688.Clos_1044	5.811e-05	52.0	COG1585@1|root,COG1585@2|Bacteria,1VD3E@1239|Firmicutes,24H38@186801|Clostridia,36IDP@31979|Clostridiaceae	186801|Clostridia	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449,NfeD
CMS3_k127_5225938_4	926550.CLDAP_32750	3.354e-34	137.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_5225938_1	383372.Rcas_1589	3.857e-85	291.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia	32061|Chloroflexia	P	ABC-3 protein	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
CMS3_k127_5225938_2	926569.ANT_20970	4.266e-74	259.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K09820,ko:K11710	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
CMS3_k127_5225938_3	1489678.RDMS_02970	2.25e-51	207.0	COG0803@1|root,COG0803@2|Bacteria,1WI8I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS3_k127_5225938_0	649638.Trad_0749	2.579e-215	676.0	COG0033@1|root,COG0033@2|Bacteria,1WJDJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_522932_0	926550.CLDAP_20100	1.566e-36	146.0	COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi	200795|Chloroflexi	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS3_k127_522932_1	357808.RoseRS_1951	4.828e-25	119.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5235819_1	926569.ANT_19390	9.513e-56	201.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS3_k127_5235819_2	926569.ANT_19400	2.767e-42	166.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CMS3_k127_5235819_0	926569.ANT_19410	2.571e-68	239.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CMS3_k127_5235819_3	926550.CLDAP_01210	1.646e-18	96.0	2ETJ3@1|root,33M2W@2|Bacteria,2G7IK@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5238610_2	471853.Bcav_2761	2.635e-39	154.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
CMS3_k127_5238610_0	926550.CLDAP_03210	8.529e-104	353.0	COG1364@1|root,COG1364@2|Bacteria,2G64K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	-	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS3_k127_5238610_1	1128421.JAGA01000003_gene3441	2.673e-79	269.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
CMS3_k127_5238647_1	1049564.TevJSym_ae00690	4.859e-39	152.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,1S3UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_5238647_0	309807.SRU_2257	2.307e-73	259.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1FJSS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
CMS3_k127_5251144_0	1038860.AXAP01000135_gene7801	2.528e-48	181.0	COG2010@1|root,COG2010@2|Bacteria,1MXXQ@1224|Proteobacteria,2U38E@28211|Alphaproteobacteria,3JU2K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_5251144_1	1487953.JMKF01000089_gene5400	5.932e-17	85.0	COG3629@1|root,COG5635@1|root,COG3629@2|Bacteria,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
CMS3_k127_5253331_2	1120949.KB903317_gene1760	2.351e-19	98.0	COG1361@1|root,COG1361@2|Bacteria,2I6N1@201174|Actinobacteria	201174|Actinobacteria	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_5253331_1	926550.CLDAP_29490	4.191e-51	185.0	COG0757@1|root,COG0757@2|Bacteria,2G6N1@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS3_k127_5253331_0	1499967.BAYZ01000181_gene4493	3.679e-89	304.0	COG0337@1|root,COG0337@2|Bacteria,2NP5Z@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.152,4.2.3.154,4.2.3.4	ko:K01735,ko:K13829,ko:K19969,ko:K21342	ko00400,ko00525,ko01100,ko01110,ko01130,ko01230,map00400,map00525,map01100,map01110,map01130,map01230	M00022,M00814,M00815	R02412,R03083,R10937	RC00002,RC00078,RC00847,RC03308	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS3_k127_5273782_0	436717.AOLE_10160	8.979e-06	58.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,1S2HV@1236|Gammaproteobacteria,3NMDN@468|Moraxellaceae	1236|Gammaproteobacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_5276521_1	926569.ANT_22300	1.803e-40	168.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
CMS3_k127_5276521_2	309801.trd_0729	1.008e-23	109.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi,27YI8@189775|Thermomicrobia	189775|Thermomicrobia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS3_k127_5276521_0	926550.CLDAP_39240	2.186e-79	280.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS3_k127_5276521_3	883.DvMF_2773	2.097e-13	75.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42QZ1@68525|delta/epsilon subdivisions,2WKYF@28221|Deltaproteobacteria,2MA59@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS3_k127_527899_2	497964.CfE428DRAFT_1740	9.831e-05	53.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
CMS3_k127_527899_1	926569.ANT_14090	5.687e-15	84.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
CMS3_k127_527899_0	240292.Ava_4108	0.0	1266.0	COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HJCN@1161|Nostocales	1117|Cyanobacteria	IQ	Acyl transferase domain in polyketide synthase (PKS) enzymes.	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_528185_4	926569.ANT_22190	1.171e-24	119.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
CMS3_k127_528185_5	797210.Halxa_2761	0.000475	51.0	COG3243@1|root,arCOG06234@1|root,arCOG06234@2157|Archaea,arCOG06344@2157|Archaea,2XSZS@28890|Euryarchaeota,23SX8@183963|Halobacteria	183963|Halobacteria	I	poly(R)-hydroxyalkanoic acid synthase subunit PhaC	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,HHH_5
CMS3_k127_528185_1	357808.RoseRS_4187	5.439e-97	327.0	COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi,37645@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM fructose-1,6-bisphosphatase, class II	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
CMS3_k127_528185_0	765420.OSCT_2904	3.372e-222	709.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi,3764C@32061|Chloroflexia	32061|Chloroflexia	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
CMS3_k127_528185_2	795666.MW7_3328	3.255e-65	229.0	COG0778@1|root,COG0778@2|Bacteria,1Q9EX@1224|Proteobacteria,2W39R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_528185_3	1121877.JQKF01000059_gene1940	7.486e-25	114.0	COG0500@1|root,COG2226@2|Bacteria,2HFKS@201174|Actinobacteria,4CNX7@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_528185_6	498761.HM1_1719	0.0005841	49.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_5286071_8	864073.HFRIS_014939	8.128e-17	86.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,4747C@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CMS3_k127_5286071_2	441620.Mpop_2813	9.478e-113	398.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,1JTHW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_5286071_4	1123360.thalar_02888	1.844e-63	244.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2UQID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,FlpD
CMS3_k127_5286071_6	330214.NIDE1139	9.532e-25	105.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,DUF3565
CMS3_k127_5286071_1	316274.Haur_0891	8.262e-179	566.0	COG2152@1|root,COG2152@2|Bacteria,2G6ZE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosidase PH1107-related	-	-	2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340	ko:K18785,ko:K20885	-	-	R10811,R10829,R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS3_k127_5286071_3	316274.Haur_0892	2.415e-88	304.0	COG1609@1|root,COG1609@2|Bacteria,2G8HR@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_5286071_0	926569.ANT_16220	9.037e-196	628.0	COG0366@1|root,COG0366@2|Bacteria,2G7K6@200795|Chloroflexi	200795|Chloroflexi	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
CMS3_k127_5286071_5	1042163.BRLA_c031950	3.102e-36	149.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,4HGXQ@91061|Bacilli	91061|Bacilli	G	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	celCD	-	2.7.1.196,2.7.1.205,3.5.1.105	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	YdjC
CMS3_k127_5286071_7	316067.Geob_0329	1.08e-17	86.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
CMS3_k127_5293186_4	525909.Afer_1408	2.679e-14	72.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CMQB@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_5293186_2	324602.Caur_3820	1.66e-53	202.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_5293186_3	700598.Niako_2510	3.129e-49	186.0	2AP53@1|root,31E6R@2|Bacteria,4P03U@976|Bacteroidetes,1IUVY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5293186_0	1499967.BAYZ01000052_gene4665	9.811e-171	584.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_5293186_1	1219077.VAZ01S_075_00050	2.071e-59	211.0	COG1247@1|root,COG1247@2|Bacteria,1QYM9@1224|Proteobacteria,1S7WX@1236|Gammaproteobacteria,1XX5R@135623|Vibrionales	135623|Vibrionales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_5293186_5	1463881.KL591010_gene5149	1.22e-12	69.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria	201174|Actinobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
CMS3_k127_5296266_0	357808.RoseRS_0779	5.674e-73	270.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,377RQ@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5299558_2	70448.A0A090N488	5.698e-11	71.0	COG0468@1|root,KOG1433@2759|Eukaryota,37MTD@33090|Viridiplantae,34GUJ@3041|Chlorophyta	3041|Chlorophyta	L	Belongs to the RecA family	RECA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS3_k127_5299558_0	485913.Krac_10271	3.155e-60	216.0	COG0500@1|root,COG2226@2|Bacteria,2GA94@200795|Chloroflexi	200795|Chloroflexi	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_5299558_1	314271.RB2654_06439	3.822e-57	223.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_5302676_0	1480694.DC28_03250	6.686e-140	456.0	COG0766@1|root,COG0766@2|Bacteria,2J5JB@203691|Spirochaetes	203691|Spirochaetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS3_k127_5302676_5	926569.ANT_22940	1.695e-13	73.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS3_k127_5302676_4	383372.Rcas_1424	6.405e-19	91.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,375ZH@32061|Chloroflexia	32061|Chloroflexia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS3_k127_5302676_3	997346.HMPREF9374_2513	1.057e-33	130.0	COG0759@1|root,COG0759@2|Bacteria,1UEB1@1239|Firmicutes,4I3UQ@91061|Bacilli,27D7Y@186824|Thermoactinomycetaceae	91061|Bacilli	S	Haemolytic	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
CMS3_k127_5302676_2	1227454.C446_09730	2.679e-36	153.0	COG1520@1|root,arCOG02492@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_5302676_1	926569.ANT_22900	4.039e-38	155.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
CMS3_k127_5302676_6	1415775.U729_1088	2.278e-05	48.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,36F11@31979|Clostridiaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
CMS3_k127_5303162_0	926550.CLDAP_39910	6.348e-57	207.0	COG1656@1|root,COG1656@2|Bacteria,2G6GZ@200795|Chloroflexi	200795|Chloroflexi	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
CMS3_k127_5308082_3	290397.Adeh_0774	1.893e-07	61.0	COG2214@1|root,COG2214@2|Bacteria,1ND5S@1224|Proteobacteria,42XS8@68525|delta/epsilon subdivisions,2WSUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5308082_1	1499967.BAYZ01000100_gene3445	9.166e-120	395.0	COG0492@1|root,COG0492@2|Bacteria,2NS2I@2323|unclassified Bacteria	2|Bacteria	O	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
CMS3_k127_5308082_0	1499967.BAYZ01000052_gene4665	3.108e-185	626.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_5308082_2	391625.PPSIR1_19814	1.864e-19	103.0	COG3591@1|root,COG3591@2|Bacteria,1QX7V@1224|Proteobacteria,43C0V@68525|delta/epsilon subdivisions,2X7BH@28221|Deltaproteobacteria,2YV6V@29|Myxococcales	28221|Deltaproteobacteria	E	Lysyl oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Lysyl_oxidase
CMS3_k127_531395_1	765912.Thimo_2887	2.126e-18	88.0	COG1132@1|root,COG1262@1|root,COG1132@2|Bacteria,COG1262@2|Bacteria,1R0RI@1224|Proteobacteria,1T59W@1236|Gammaproteobacteria,1X2VF@135613|Chromatiales	1224|Proteobacteria	V	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
CMS3_k127_531395_0	926569.ANT_03400	6.32e-113	377.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5319098_0	35754.JNYJ01000019_gene80	3.336e-103	368.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12
CMS3_k127_5319098_1	518766.Rmar_1760	4.835e-05	51.0	COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1FJT3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_5319425_1	867903.ThesuDRAFT_01941	2.244e-84	288.0	COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,24DS0@186801|Clostridia	186801|Clostridia	S	Peptidoglycan binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
CMS3_k127_5319425_2	500153.JOEK01000009_gene4819	4.548e-66	234.0	COG0566@1|root,COG0566@2|Bacteria,2GP9S@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS3_k127_5319425_0	1121468.AUBR01000034_gene1373	1.508e-123	413.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,42F2U@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1,HHH_3
CMS3_k127_5321741_1	926569.ANT_23520	7.772e-39	156.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
CMS3_k127_5321741_0	926569.ANT_23560	1.617e-48	180.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
CMS3_k127_5323123_4	221027.JO40_07355	1.055e-49	182.0	COG0041@1|root,COG0041@2|Bacteria,2J96B@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS3_k127_5323123_1	926550.CLDAP_39520	3.274e-123	403.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi	200795|Chloroflexi	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS3_k127_5323123_0	670487.Ocepr_0685	0.0	1229.0	COG0046@1|root,COG0047@1|root,COG1828@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,COG1828@2|Bacteria,1WIR9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_5323123_3	36080.S2K3D5	6.317e-72	247.0	COG0138@1|root,KOG2555@2759|Eukaryota,38H8U@33154|Opisthokonta,3NY4C@4751|Fungi,1GRSZ@112252|Fungi incertae sedis	4751|Fungi	F	AICARFT/IMPCHase bienzyme	ADE17	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0003937,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009060,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009653,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019637,GO:0019693,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0032502,GO:0032505,GO:0034293,GO:0034641,GO:0034654,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045333,GO:0046040,GO:0046390,GO:0046483,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903046	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS3_k127_5323123_5	643648.Slip_1920	2.809e-27	120.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,42KK8@68298|Syntrophomonadaceae	186801|Clostridia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
CMS3_k127_5323123_2	502025.Hoch_5119	3.429e-91	305.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS3_k127_532377_0	1128421.JAGA01000001_gene2038	9.431e-63	239.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,SpoIIE
CMS3_k127_532377_1	1121875.KB907549_gene1769	8.816e-43	159.0	COG0745@1|root,COG0745@2|Bacteria,4NVP7@976|Bacteroidetes,1I5B4@117743|Flavobacteriia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_532377_2	555088.DealDRAFT_2880	5.447e-36	142.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes	1239|Firmicutes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_5327798_1	926569.ANT_23460	1.963e-148	479.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS3_k127_5327798_2	1173024.KI912152_gene713	1.629e-45	170.0	2B7I5@1|root,320NJ@2|Bacteria,1G6ZH@1117|Cyanobacteria,1JJW9@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5327798_0	926569.ANT_10620	3.813e-196	644.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
CMS3_k127_5327798_3	298655.KI912266_gene3848	0.0009664	49.0	COG3173@1|root,COG3173@2|Bacteria,2I8YI@201174|Actinobacteria,4ETK9@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_5329372_0	926550.CLDAP_09690	3.274e-126	436.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_5329372_1	1121957.ATVL01000008_gene4422	1.087e-30	124.0	COG2267@1|root,COG2267@2|Bacteria,4PKB6@976|Bacteroidetes,47JMT@768503|Cytophagia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_5337828_0	1191523.MROS_2367	2.335e-183	587.0	COG3808@1|root,COG3808@2|Bacteria	2|Bacteria	C	hydrogen-translocating pyrophosphatase activity	hppA	-	3.6.1.1	ko:K01507,ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS3_k127_5337828_1	1128421.JAGA01000002_gene1016	1.141e-94	321.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS3_k127_5337828_2	926569.ANT_18700	2.543e-55	222.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
CMS3_k127_5343022_2	635013.TherJR_0468	0.0008316	44.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199,ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
CMS3_k127_5343022_0	313606.M23134_04614	4.559e-96	344.0	COG4932@1|root,COG4932@2|Bacteria,4PME1@976|Bacteroidetes	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5343022_1	357808.RoseRS_1785	6.11e-42	156.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_5343885_0	626418.bglu_2g12850	2.774e-190	610.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2VHAK@28216|Betaproteobacteria,1K410@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_535964_3	243164.DET1639	4.651e-10	63.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi,34DG3@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS3_k127_535964_0	880073.Calab_1764	2.268e-115	400.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_535964_1	926569.ANT_28000	3.674e-64	242.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_535964_2	298653.Franean1_4351	1.935e-26	113.0	COG0664@1|root,COG1225@1|root,COG1994@1|root,COG0664@2|Bacteria,COG1225@2|Bacteria,COG1994@2|Bacteria,2IBWH@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase M50	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	AhpC-TSA,FHA,Yop-YscD_cpl,cNMP_binding
CMS3_k127_5361154_10	926569.ANT_20360	3.388e-07	51.0	COG0438@1|root,COG0438@2|Bacteria,2G60E@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_5361154_1	926569.ANT_20350	3.827e-111	374.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5361154_0	926550.CLDAP_27890	1.969e-120	399.0	COG0438@1|root,COG0438@2|Bacteria,2G7W9@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS3_k127_5361154_6	326427.Cagg_0801	1.968e-52	197.0	COG1216@1|root,COG1216@2|Bacteria,2G7UG@200795|Chloroflexi,3764Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS3_k127_5361154_4	926550.CLDAP_27810	3.891e-71	251.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS3_k127_5361154_3	926569.ANT_20310	4.423e-81	288.0	COG3307@1|root,COG3307@2|Bacteria,2G7A2@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_5361154_9	1444711.CCJF01000004_gene2392	3.573e-18	97.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
CMS3_k127_5361154_5	1128421.JAGA01000002_gene754	1.854e-55	207.0	COG1216@1|root,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_5361154_2	383372.Rcas_0458	1.908e-93	323.0	COG0438@1|root,COG0438@2|Bacteria,2G7Z3@200795|Chloroflexi,376IC@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5361154_7	1173025.GEI7407_0964	9.201e-39	159.0	COG1216@1|root,COG1216@2|Bacteria,1G09N@1117|Cyanobacteria,1H8HE@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2
CMS3_k127_5361154_8	331869.BAL199_04134	1.007e-24	110.0	2DTTJ@1|root,32UVW@2|Bacteria,1NGQC@1224|Proteobacteria,2UKGP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_5367309_0	765420.OSCT_2742	4.458e-45	172.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_5367309_2	1122222.AXWR01000049_gene1616	1.012e-07	56.0	COG4914@1|root,COG4914@2|Bacteria,1WNGG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_53677_8	485913.Krac_5027	9.745e-13	81.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_53677_3	6500.XP_005092325.1	1.601e-101	342.0	COG1171@1|root,KOG1251@2759|Eukaryota,3AJVW@33154|Opisthokonta,3BZSW@33208|Metazoa,3DG6W@33213|Bilateria	33208|Metazoa	ET	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS3_k127_53677_2	1121405.dsmv_0956	2.07e-104	351.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MKU8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS3_k127_53677_0	326427.Cagg_0026	1.941e-121	399.0	COG2355@1|root,COG2355@2|Bacteria,2G5Y0@200795|Chloroflexi,375WA@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M19 renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_53677_6	748247.AZKH_p0460	5.802e-32	128.0	COG2346@1|root,COG2346@2|Bacteria,1N005@1224|Proteobacteria,2VUPJ@28216|Betaproteobacteria,2KZHR@206389|Rhodocyclales	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_53677_1	926550.CLDAP_04170	1.33e-112	374.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS3_k127_53677_5	926550.CLDAP_06330	6.62e-44	164.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS3_k127_53677_7	253839.SSNG_00273	8.007e-22	102.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_53677_4	861299.J421_5622	3.98e-56	224.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5622|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5367831_3	316274.Haur_4243	6.917e-22	102.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	M1-584	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_5367831_0	326427.Cagg_2801	7.958e-43	177.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS3_k127_5367831_1	1177594.MIC448_1540009	5.846e-33	140.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4FNEZ@85023|Microbacteriaceae	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_5367831_2	1111069.TCCBUS3UF1_12720	3.857e-25	115.0	COG1173@1|root,COG1173@2|Bacteria,1WIH4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_5369922_0	926550.CLDAP_39080	0.0	1399.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS3_k127_5369922_1	1232430.CAVG010000140_gene1381	3.903e-40	152.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,4GZ53@90964|Staphylococcaceae	91061|Bacilli	E	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_5377110_4	383372.Rcas_0864	7.077e-24	117.0	COG0318@1|root,COG0318@2|Bacteria,2GBKJ@200795|Chloroflexi,3781K@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5377110_1	383372.Rcas_3059	4.669e-108	359.0	COG1131@1|root,COG1131@2|Bacteria,2GAQH@200795|Chloroflexi,3753M@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_5377110_3	324602.Caur_2041	1.225e-35	149.0	COG1668@1|root,COG1668@2|Bacteria,2GBIJ@200795|Chloroflexi,3768Z@32061|Chloroflexia	32061|Chloroflexia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS3_k127_5377110_6	720554.Clocl_0443	3.408e-07	63.0	COG3064@1|root,COG4942@1|root,COG3064@2|Bacteria,COG4942@2|Bacteria,1V7YD@1239|Firmicutes,24BHW@186801|Clostridia	186801|Clostridia	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5377110_0	1521187.JPIM01000176_gene933	4.484e-123	402.0	COG0714@1|root,COG0714@2|Bacteria,2GACN@200795|Chloroflexi,375BZ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_5377110_2	357808.RoseRS_1889	8.841e-68	243.0	COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_5377110_5	383372.Rcas_3820	4.256e-14	73.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_5378267_7	1223523.H340_01744	0.0004847	53.0	COG0657@1|root,COG0657@2|Bacteria,2IGUD@201174|Actinobacteria	201174|Actinobacteria	I	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6,FSH1,Peptidase_S9
CMS3_k127_5378267_2	309807.SRU_1659	8.06e-119	406.0	COG3174@1|root,COG3174@2|Bacteria,4NKP6@976|Bacteroidetes,1FJWC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
CMS3_k127_5378267_3	357808.RoseRS_0204	6.076e-59	218.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
CMS3_k127_5378267_5	316274.Haur_2144	1.984e-19	94.0	COG0784@1|root,COG0784@2|Bacteria,2GB7B@200795|Chloroflexi,377HM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS3_k127_5378267_6	316274.Haur_1271	6.304e-17	86.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HATPase_c,Response_reg
CMS3_k127_5378267_4	926569.ANT_11840	6.899e-21	98.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_5378267_1	926550.CLDAP_05420	8.514e-160	514.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_5378267_0	868595.Desca_2486	1.937e-177	572.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS3_k127_5390121_0	926550.CLDAP_11380	5.918e-284	897.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_5396363_2	251229.Chro_3824	5.293e-25	113.0	COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,3VHWS@52604|Pleurocapsales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_5396363_1	292459.STH493	2.198e-34	147.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_5396363_0	1121434.AULY01000010_gene2320	9.885e-69	239.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_5401889_3	395961.Cyan7425_0057	9.162e-57	211.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,3KIRB@43988|Cyanothece	1117|Cyanobacteria	CG	glycosyl transferase family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
CMS3_k127_5401889_0	1541065.JRFE01000014_gene1505	2.109e-177	614.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG5276@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1G8F1@1117|Cyanobacteria,3VMVS@52604|Pleurocapsales	1117|Cyanobacteria	M	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
CMS3_k127_5401889_4	1229172.JQFA01000002_gene4761	1.467e-16	84.0	COG5002@1|root,COG5002@2|Bacteria,1GQU9@1117|Cyanobacteria,1HH44@1150|Oscillatoriales	1117|Cyanobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,dCache_1
CMS3_k127_5401889_1	867903.ThesuDRAFT_01503	1.816e-67	238.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24IAA@186801|Clostridia	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_5401889_2	552811.Dehly_0707	1.975e-60	217.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,2G6SR@200795|Chloroflexi,34CV6@301297|Dehalococcoidia	200795|Chloroflexi	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00266,ko:K03388	ko00250,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	M00356,M00357,M00563,M00567	R00093,R00114,R00248,R04540,R11928,R11931,R11943,R11944	RC00006,RC00010,RC00011,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS3_k127_5403552_9	593117.TGAM_1504	1.414e-33	147.0	arCOG02559@1|root,arCOG03264@1|root,arCOG06661@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG06661@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	28890|Euryarchaeota	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA,Pkinase
CMS3_k127_5403552_0	2002.JOEQ01000016_gene7347	2.859e-149	529.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
CMS3_k127_5403552_6	1123284.KB899042_gene1176	1.741e-49	205.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26NEC@186821|Sporolactobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_5403552_3	1499967.BAYZ01000182_gene4446	2.784e-119	393.0	COG1816@1|root,COG1816@2|Bacteria,2NR0J@2323|unclassified Bacteria	2|Bacteria	F	Adenosine/AMP deaminase	add	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.2,3.5.4.4,3.5.4.40	ko:K01488,ko:K18286,ko:K21053	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01244,R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
CMS3_k127_5403552_2	1128421.JAGA01000002_gene860	1.537e-124	407.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_5403552_8	1541065.JRFE01000009_gene4470	3.594e-45	166.0	COG2337@1|root,COG2337@2|Bacteria,1GM25@1117|Cyanobacteria,3VMWB@52604|Pleurocapsales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CMS3_k127_5403552_11	203124.Tery_0629	3.415e-11	66.0	COG0864@1|root,COG0864@2|Bacteria,1GAJD@1117|Cyanobacteria,1HDWI@1150|Oscillatoriales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5403552_1	1382359.JIAL01000001_gene3025	4.04e-147	476.0	COG0277@1|root,COG0277@2|Bacteria,3Y6C5@57723|Acidobacteria,2JKMQ@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM FAD linked oxidase	-	-	1.1.3.41	ko:K00594	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R07152,R11620	RC00108,RC00133	ko00000,ko00001,ko01000	-	-	-	ALO,FAD_binding_4
CMS3_k127_5403552_7	251221.35214034	2.074e-48	178.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_5403552_4	926560.KE387023_gene3758	1.03e-76	270.0	COG1506@1|root,COG1506@2|Bacteria,1WI4E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Hydrolase_4,Peptidase_S9
CMS3_k127_5403552_10	316275.VSAL_I1494	1.348e-20	94.0	COG1247@1|root,COG1247@2|Bacteria,1RC8Z@1224|Proteobacteria,1THNM@1236|Gammaproteobacteria,1XWXT@135623|Vibrionales	135623|Vibrionales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS3_k127_5403552_5	1499967.BAYZ01000041_gene2318	7.674e-54	198.0	COG1207@1|root,COG1207@2|Bacteria,2NQ8F@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
CMS3_k127_5404314_6	926554.KI912620_gene1119	1.859e-23	100.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_5404314_1	926554.KI912620_gene1118	1.002e-133	434.0	COG4586@1|root,COG4586@2|Bacteria	2|Bacteria	S	(ABC) transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5404314_0	869210.Marky_1372	4.039e-172	559.0	COG0557@1|root,COG0557@2|Bacteria,1WIKR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	ribonuclease II	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
CMS3_k127_5404314_5	1123326.JFBL01000005_gene1156	1.519e-28	122.0	COG1280@1|root,COG1280@2|Bacteria,1RD16@1224|Proteobacteria	1224|Proteobacteria	E	threonine efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS3_k127_5404314_7	379066.GAU_0791	0.0002451	48.0	2AF1B@1|root,314ZP@2|Bacteria,1ZV60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS3_k127_5404314_4	1128421.JAGA01000003_gene3237	2.232e-32	141.0	COG2984@1|root,COG2984@2|Bacteria,2NPCT@2323|unclassified Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	ABC-SBP	-	-	ko:K01989,ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CMS3_k127_5404314_2	1121459.AQXE01000010_gene1951	9.122e-85	288.0	COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,42N3W@68525|delta/epsilon subdivisions,2WJD3@28221|Deltaproteobacteria,2M88J@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
CMS3_k127_5404314_3	1121121.KB894288_gene2866	8.152e-54	201.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,26RIM@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
CMS3_k127_5405033_4	696747.NIES39_A07680	1.043e-08	67.0	COG1357@1|root,COG1357@2|Bacteria,1G5J5@1117|Cyanobacteria,1HAW7@1150|Oscillatoriales	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_5405033_1	1128421.JAGA01000002_gene84	5.187e-37	148.0	COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria	2|Bacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_5405033_0	926550.CLDAP_15430	4.286e-160	509.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
CMS3_k127_5405033_2	1280390.CBQR020000036_gene785	4.708e-30	135.0	COG5650@1|root,COG5650@2|Bacteria,1TQVD@1239|Firmicutes,4HEQ0@91061|Bacilli,276JI@186822|Paenibacillaceae	91061|Bacilli	O	integral membrane protein	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2
CMS3_k127_5405606_7	160799.PBOR_27925	1.004e-05	51.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,27634@186822|Paenibacillaceae	91061|Bacilli	G	PFAM glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CBM_6,Glyco_hydro_16,SLH
CMS3_k127_5405606_0	1293054.HSACCH_00342	3.728e-76	266.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3WAMN@53433|Halanaerobiales	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10238	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
CMS3_k127_5405606_6	1382356.JQMP01000003_gene1665	3.249e-06	55.0	COG0346@1|root,COG0346@2|Bacteria,2GB9Q@200795|Chloroflexi,27YDI@189775|Thermomicrobia	189775|Thermomicrobia	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5405606_2	1449063.JMLS01000007_gene3530	7.005e-46	172.0	COG2318@1|root,COG2318@2|Bacteria,1V6UF@1239|Firmicutes,4HIPX@91061|Bacilli,26SUI@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
CMS3_k127_5405606_5	1463858.JOHR01000002_gene5979	6.188e-07	53.0	COG0500@1|root,COG2226@2|Bacteria,2GKH6@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_5405606_3	1117108.PAALTS15_22218	8.989e-45	171.0	COG0500@1|root,COG0500@2|Bacteria,1TPTW@1239|Firmicutes,4ISQV@91061|Bacilli,26RVN@186822|Paenibacillaceae	91061|Bacilli	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_5405606_4	1137268.AZXF01000012_gene3508	1.863e-08	64.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
CMS3_k127_5407306_4	1134413.ANNK01000091_gene105	8.26e-11	70.0	COG2717@1|root,COG2717@2|Bacteria,1U9I2@1239|Firmicutes,4IJNK@91061|Bacilli,1ZCC2@1386|Bacillus	91061|Bacilli	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
CMS3_k127_5407306_2	251221.35212350	1.673e-23	115.0	COG3534@1|root,COG3534@2|Bacteria,1GD2K@1117|Cyanobacteria	1117|Cyanobacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5407306_3	66692.ABC3727	1.421e-21	109.0	COG4099@1|root,COG4099@2|Bacteria,1V3AJ@1239|Firmicutes,4HHP0@91061|Bacilli,1ZEXR@1386|Bacillus	91061|Bacilli	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,CHB_HEX_C_1,Esterase,Esterase_phd,Peptidase_S9,SLH
CMS3_k127_5407306_0	1173028.ANKO01000168_gene4341	1.881e-118	412.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1G3MS@1117|Cyanobacteria,1H7EZ@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_5407306_1	1541065.JRFE01000014_gene1220	1.481e-45	173.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1,Sulfotransfer_3
CMS3_k127_54154_1	926569.ANT_05530	1.154e-85	295.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS3_k127_54154_0	926569.ANT_05540	2.883e-108	359.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS3_k127_54154_2	1521187.JPIM01000042_gene1850	1.273e-26	114.0	2FFVE@1|root,347SF@2|Bacteria,2GB3K@200795|Chloroflexi,377UV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5415938_2	309801.trd_0544	2.893e-53	201.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
CMS3_k127_5415938_0	1123073.KB899244_gene303	1.12e-127	418.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1X46A@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS3_k127_5415938_1	357808.RoseRS_3414	1.556e-122	401.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi,3762T@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS3_k127_5415938_3	1479237.JMLY01000001_gene2645	0.0004205	51.0	COG3568@1|root,COG3568@2|Bacteria,1R977@1224|Proteobacteria,1RTF2@1236|Gammaproteobacteria,466AF@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Phosphodiest
CMS3_k127_5422479_0	926560.KE387023_gene2131	4.939e-111	364.0	COG3694@1|root,COG3694@2|Bacteria,1WM9D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
CMS3_k127_5422479_2	65393.PCC7424_0264	3.233e-11	65.0	COG3514@1|root,COG3514@2|Bacteria,1GA67@1117|Cyanobacteria,3KKKP@43988|Cyanothece	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
CMS3_k127_5422479_1	643867.Ftrac_2367	5.794e-34	139.0	COG0596@1|root,COG0596@2|Bacteria,4PNPN@976|Bacteroidetes,47XAU@768503|Cytophagia	976|Bacteroidetes	S	Ndr family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS3_k127_5422917_2	391625.PPSIR1_31478	1.184e-41	158.0	COG0566@1|root,COG0566@2|Bacteria,1Q9ZD@1224|Proteobacteria,42VPG@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	rRNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CMS3_k127_5422917_3	1121091.AUMP01000003_gene2690	7.045e-23	105.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli	91061|Bacilli	K	Histone acetyltransferase HPA2 and related acetyltransferases	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_5422917_1	926550.CLDAP_05850	3.942e-166	527.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_5422917_0	926569.ANT_14720	6.392e-206	650.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_542710_5	177437.HRM2_16760	4.582e-18	85.0	COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria,2MIKC@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
CMS3_k127_542710_2	1125863.JAFN01000001_gene3324	1.76e-78	271.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,42NBP@68525|delta/epsilon subdivisions,2WKS7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
CMS3_k127_542710_6	767817.Desgi_2016	1.751e-15	86.0	COG1456@1|root,COG1456@2|Bacteria,1V556@1239|Firmicutes,24I6Z@186801|Clostridia,262FN@186807|Peptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
CMS3_k127_542710_1	429009.Adeg_0345	1.032e-79	284.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,42FH6@68295|Thermoanaerobacterales	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_542710_4	1101189.AQUO01000002_gene426	2.978e-20	105.0	COG0685@1|root,COG0685@2|Bacteria,1RHDY@1224|Proteobacteria,2U4I0@28211|Alphaproteobacteria,2PYRU@265|Paracoccus	28211|Alphaproteobacteria	E	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
CMS3_k127_542710_3	760568.Desku_2692	2.817e-62	226.0	COG3634@1|root,COG3634@2|Bacteria,1UIUB@1239|Firmicutes,25ES4@186801|Clostridia,267GT@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2,Thioredoxin_3
CMS3_k127_542710_0	1480694.DC28_13880	3.161e-204	644.0	COG0281@1|root,COG0281@2|Bacteria,2J5DN@203691|Spirochaetes	203691|Spirochaetes	C	Malic enzyme, NAD binding domain	mdh	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
CMS3_k127_5428265_2	552811.Dehly_1505	5.83e-37	153.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi,34D0N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS3_k127_5428265_3	485913.Krac_12050	7.383e-20	96.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5428265_0	926569.ANT_10550	1.432e-138	460.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_5428265_1	926569.ANT_26470	7.399e-70	244.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
CMS3_k127_5430378_1	926569.ANT_03800	5.623e-61	216.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS3_k127_5430378_2	926569.ANT_01450	2.718e-54	196.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
CMS3_k127_5430378_0	926550.CLDAP_30410	1.999e-69	253.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
CMS3_k127_5433178_1	926569.ANT_11210	4.502e-135	446.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
CMS3_k127_5433178_0	926569.ANT_24850	1.038e-138	454.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_5433178_5	357808.RoseRS_0976	2.629e-06	60.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi,376E4@32061|Chloroflexia	32061|Chloroflexia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5433178_4	159749.K0SDG5	2.84e-07	61.0	COG2335@1|root,KOG1437@2759|Eukaryota	2759|Eukaryota	M	regulation of chemokine (C-C motif) ligand 2 secretion	-	-	-	ko:K19519	-	-	-	-	ko00000,ko04516	-	-	-	Fasciclin
CMS3_k127_5433178_6	456442.Mboo_0021	1.174e-05	55.0	COG2335@1|root,arCOG03335@2157|Archaea	2157|Archaea	M	Beta-Ig-H3 fasciclin	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS3_k127_5433178_3	373994.Riv7116_1253	6.008e-67	242.0	COG0703@1|root,COG0703@2|Bacteria,1GJPH@1117|Cyanobacteria,1HS8A@1161|Nostocales	1117|Cyanobacteria	E	Shikimate kinase	-	-	-	-	-	-	-	-	-	-	-	-	SKI
CMS3_k127_5433178_2	748727.CLJU_c22210	3.099e-91	306.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,36DHZ@31979|Clostridiaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
CMS3_k127_5435443_2	1122223.KB890687_gene2936	8.657e-141	460.0	COG0015@1|root,COG0015@2|Bacteria,1WMD3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Adenylosuccinate lyase C-terminus	-	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	Lyase_1
CMS3_k127_5435443_6	391625.PPSIR1_26958	2.812e-50	191.0	COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,42RJF@68525|delta/epsilon subdivisions,2WNGK@28221|Deltaproteobacteria,2Z0BU@29|Myxococcales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_5435443_8	272134.KB731324_gene3722	1.19e-23	107.0	COG1572@1|root,COG1572@2|Bacteria,1GBQN@1117|Cyanobacteria	1117|Cyanobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5435443_1	498761.HM1_2785	3.982e-176	569.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_5435443_4	1121422.AUMW01000005_gene644	1.437e-106	357.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,260KC@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM formate dehydrogenase, alpha subunit	fdhB	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_5435443_0	335543.Sfum_2713	3.152e-205	652.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR9E@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hoxF	-	1.6.5.3	ko:K00124,ko:K00335,ko:K05587	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_5435443_5	926550.CLDAP_28500	1.871e-63	222.0	COG1905@1|root,COG1905@2|Bacteria,2G6Q5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	hoxE	-	1.6.5.3	ko:K00334,ko:K05586	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS3_k127_5435443_7	290397.Adeh_0914	4.791e-35	139.0	COG3427@1|root,COG3427@2|Bacteria,1PB5Q@1224|Proteobacteria	1224|Proteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_5435443_10	1307761.L21SP2_3286	3.303e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
CMS3_k127_5435443_9	316274.Haur_1112	2.419e-22	111.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	ko:K16247	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,NB-ARC,TPR_12,TPR_7
CMS3_k127_5435443_3	1121106.JQKB01000007_gene1070	2.827e-124	408.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2JV0E@204441|Rhodospirillales	204441|Rhodospirillales	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5442047_1	926569.ANT_01240	6.679e-173	550.0	COG0624@1|root,COG0624@2|Bacteria,2G8AH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_5442047_0	926569.ANT_14510	2.462e-256	830.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_5442047_2	1128421.JAGA01000001_gene2230	6.58e-142	466.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K03520,ko:K07302	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
CMS3_k127_5442869_1	1144275.COCOR_03695	2.958e-18	98.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5442869_2	530564.Psta_4082	2.576e-17	93.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,2IYH3@203682|Planctomycetes	203682|Planctomycetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,SdrD_B
CMS3_k127_5442869_0	1144275.COCOR_03695	1.454e-41	166.0	COG3055@1|root,COG3055@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5448971_2	455632.SGR_574	9.862e-10	64.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5448971_1	926569.ANT_11630	2.508e-102	342.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS3_k127_5448971_0	1123250.KB908387_gene550	1.981e-173	562.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS3_k127_5450678_2	1128421.JAGA01000002_gene1310	9.257e-58	204.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5450678_1	383372.Rcas_4084	2.24e-70	252.0	COG1209@1|root,COG1209@2|Bacteria,2GBKU@200795|Chloroflexi,3781T@32061|Chloroflexia	32061|Chloroflexia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_5450678_0	1521187.JPIM01000182_gene1886	6.248e-189	601.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,375CN@32061|Chloroflexia	32061|Chloroflexia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_5450678_3	118005.AWNK01000007_gene791	2.524e-12	70.0	COG0721@1|root,COG0721@2|Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
CMS3_k127_5460315_1	926550.CLDAP_28170	7.765e-46	182.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_5460315_0	926550.CLDAP_23150	6.202e-87	313.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_5474749_0	309801.trd_1067	6.229e-249	781.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi,27XPW@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
CMS3_k127_5477117_0	1487923.DP73_03235	1.571e-109	369.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,26000@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_5482270_2	926569.ANT_22420	1.8e-37	143.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS3_k127_5482270_4	926569.ANT_22430	1.509e-25	108.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi	200795|Chloroflexi	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS3_k127_5482270_3	926569.ANT_22440	6.596e-30	135.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
CMS3_k127_5482270_0	926569.ANT_22450	2.867e-92	321.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS3_k127_5482270_1	322710.Avin_21330	8.088e-49	182.0	COG2175@1|root,COG2175@2|Bacteria,1P6UZ@1224|Proteobacteria,1T14G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
CMS3_k127_5483839_2	713587.THITH_08240	3.496e-31	129.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,1S03N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	WD domain, G-beta repeat	-	-	-	ko:K20332	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	WD40
CMS3_k127_5483839_1	324602.Caur_3820	7.034e-42	162.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_5483839_0	211114.JOEF01000010_gene3360	1.431e-46	183.0	COG3049@1|root,COG3049@2|Bacteria,2IA2S@201174|Actinobacteria,4E17S@85010|Pseudonocardiales	201174|Actinobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_5483839_3	1499967.BAYZ01000028_gene1229	2.801e-28	123.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5483839_4	745776.DGo_PC0249	1.464e-14	77.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
CMS3_k127_5483839_5	196490.AUEZ01000216_gene3698	9.178e-06	50.0	COG2801@1|root,COG2801@2|Bacteria,1N4JW@1224|Proteobacteria,2UEHC@28211|Alphaproteobacteria,3K0M2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	HTH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21
CMS3_k127_5485281_1	266117.Rxyl_2810	3.528e-67	248.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_5485281_0	485913.Krac_10496	3.66e-88	296.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_5485281_2	1042877.GQS_00515	9.907e-49	186.0	arCOG10088@1|root,arCOG10088@2157|Archaea,2Y2WP@28890|Euryarchaeota,2437S@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5485281_4	861299.J421_1359	1.43e-13	84.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_5485281_3	314287.GB2207_10181	6.002e-25	109.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1J9XF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS3_k127_5493730_5	446468.Ndas_1470	1.151e-14	85.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4EJ30@85012|Streptosporangiales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
CMS3_k127_5493730_0	326427.Cagg_2274	9.649e-208	664.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,2G64W@200795|Chloroflexi,376VC@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase
CMS3_k127_5493730_4	1210884.HG799465_gene11651	4.908e-46	172.0	2F7UQ@1|root,3408S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5493730_1	1122604.JONR01000006_gene2635	1.395e-102	343.0	COG0596@1|root,COG0596@2|Bacteria,1QIT9@1224|Proteobacteria,1RNP9@1236|Gammaproteobacteria,1X5DS@135614|Xanthomonadales	135614|Xanthomonadales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_5493730_3	479434.Sthe_1534	3.255e-53	189.0	COG0599@1|root,COG0599@2|Bacteria,2GA0S@200795|Chloroflexi,27YG5@189775|Thermomicrobia	189775|Thermomicrobia	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_5493730_2	1121946.AUAX01000004_gene965	6.737e-88	306.0	28KUD@1|root,2ZAB6@2|Bacteria,2IACK@201174|Actinobacteria,4D94P@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5493730_6	479434.Sthe_0156	1.819e-13	83.0	COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_549390_2	383372.Rcas_0753	1.268e-124	421.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
CMS3_k127_549390_1	357808.RoseRS_1641	1.117e-132	434.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,3758E@32061|Chloroflexia	32061|Chloroflexia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS3_k127_549390_3	926550.CLDAP_37540	7.653e-114	376.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS3_k127_549390_4	926550.CLDAP_37550	1.496e-106	357.0	COG1177@1|root,COG1177@2|Bacteria,2G6DH@200795|Chloroflexi	200795|Chloroflexi	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS3_k127_549390_0	926550.CLDAP_37560	2.484e-154	496.0	COG0687@1|root,COG0687@2|Bacteria,2G6U4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CMS3_k127_5495620_0	485913.Krac_1423	4.503e-90	306.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
CMS3_k127_5495620_1	926692.AZYG01000026_gene1759	8.074e-37	147.0	COG4974@1|root,COG4974@2|Bacteria,1V98H@1239|Firmicutes	1239|Firmicutes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
CMS3_k127_5499537_0	926550.CLDAP_17870	3.796e-162	516.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS3_k127_5499537_1	1117108.PAALTS15_22218	3.495e-38	153.0	COG0500@1|root,COG0500@2|Bacteria,1TPTW@1239|Firmicutes,4ISQV@91061|Bacilli,26RVN@186822|Paenibacillaceae	91061|Bacilli	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_5506745_1	1408254.T458_08030	8.612e-72	251.0	COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,4HC07@91061|Bacilli	91061|Bacilli	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
CMS3_k127_5506745_2	1123501.KB902276_gene1138	6.673e-17	83.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
CMS3_k127_5506745_0	292459.STH816	4.824e-93	315.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS3_k127_5514103_0	525904.Tter_0977	0.0	1195.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS3_k127_5514817_2	246197.MXAN_1290	2.64e-43	171.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	hsK1	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5514817_6	1173026.Glo7428_3606	3.405e-09	70.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
CMS3_k127_5514817_3	118168.MC7420_3505	4.976e-36	145.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,Methyltransf_32
CMS3_k127_5514817_5	1173027.Mic7113_4437	1.892e-24	111.0	COG1073@1|root,COG1073@2|Bacteria,1G54F@1117|Cyanobacteria,1HAMN@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
CMS3_k127_5514817_1	1157490.EL26_09010	6.349e-67	234.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_5514817_0	649638.Trad_2420	1.72e-125	409.0	COG0405@1|root,COG0405@2|Bacteria,1WI9V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_55191_3	926569.ANT_25150	1.664e-23	103.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_55191_2	1121377.KB906436_gene925	4.171e-42	164.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS3_k127_55191_1	324602.Caur_2243	1.298e-65	236.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi,375I3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS3_k127_55191_0	373994.Riv7116_1296	3.035e-77	269.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,1HMT6@1161|Nostocales	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
CMS3_k127_5529875_3	886293.Sinac_7551	8.425e-44	165.0	COG0491@1|root,COG0491@2|Bacteria,2J4KU@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_5529875_2	756067.MicvaDRAFT_0614	2.179e-80	299.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H7F4@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,TPR_1,TPR_8,Thioesterase
CMS3_k127_5529875_0	251229.Chro_1925	0.0	1265.0	COG0778@1|root,COG1020@1|root,COG0778@2|Bacteria,COG1020@2|Bacteria,1GBN8@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Phosphopantetheine attachment site	-	-	-	ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Nitroreductase,PP-binding
CMS3_k127_5529875_1	272134.KB731324_gene4680	4.257e-171	601.0	COG0318@1|root,COG0318@2|Bacteria,1G3MS@1117|Cyanobacteria,1H7EZ@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_5529875_4	880072.Desac_0993	1.719e-16	94.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1R682@1224|Proteobacteria,42P91@68525|delta/epsilon subdivisions,2WKQI@28221|Deltaproteobacteria,2MR7I@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
CMS3_k127_5529875_5	1121033.AUCF01000004_gene4725	9.085e-16	92.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JQ4H@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9
CMS3_k127_5530870_2	926569.ANT_28060	4.049e-88	295.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS3_k127_5530870_3	326427.Cagg_3135	3.494e-79	275.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS3_k127_5530870_0	251229.Chro_2393	1.625e-250	790.0	COG1770@1|root,COG1770@2|Bacteria,1G1RH@1117|Cyanobacteria,3VNK1@52604|Pleurocapsales	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_5530870_1	926550.CLDAP_13110	1.709e-98	332.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5530870_4	926550.CLDAP_15380	8.031e-78	267.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5537182_0	1432050.IE4771_CH00463	1.56e-110	375.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TUPK@28211|Alphaproteobacteria,4BDDQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	ix monomethyl ester oxidative cyclase	bchE	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_5537182_2	5786.XP_003294367.1	1.34e-13	82.0	KOG1738@1|root,KOG1738@2759|Eukaryota,3X89W@554915|Amoebozoa	554915|Amoebozoa	U	connector enhancer of kinase suppressor of Ras	-	GO:0001881,GO:0003674,GO:0005488,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005794,GO:0005802,GO:0005829,GO:0005886,GO:0006810,GO:0006996,GO:0007032,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0010256,GO:0012505,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016197,GO:0016482,GO:0023051,GO:0031252,GO:0031410,GO:0031982,GO:0031984,GO:0035091,GO:0042147,GO:0043112,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044260,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0050789,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055037,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0097708,GO:0098791,GO:1901981	-	-	-	-	-	-	-	-	-	-	PH
CMS3_k127_5537182_1	96561.Dole_2364	2.138e-81	282.0	COG0530@1|root,COG0530@2|Bacteria,1PMPU@1224|Proteobacteria,43A4H@68525|delta/epsilon subdivisions,2X26D@28221|Deltaproteobacteria,2MM3E@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
CMS3_k127_5537182_3	526227.Mesil_1285	0.0007093	49.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,FecR,LysM,Peptidase_M15_2,Peptidase_M74
CMS3_k127_5538330_1	270374.MELB17_00705	2.477e-61	218.0	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,1RR0H@1236|Gammaproteobacteria,466A6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	haloacid dehalogenase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_5538330_2	1525715.IX54_02560	7.523e-47	181.0	COG0679@1|root,COG0679@2|Bacteria,1MY23@1224|Proteobacteria,2TR4M@28211|Alphaproteobacteria,2PVXZ@265|Paracoccus	28211|Alphaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS3_k127_5538330_0	497964.CfE428DRAFT_0631	1.117e-152	503.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_5539087_0	324602.Caur_3196	4.297e-94	317.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
CMS3_k127_5539087_1	326427.Cagg_3286	7.422e-47	180.0	COG1943@1|root,COG1943@2|Bacteria,2GBSA@200795|Chloroflexi,376EW@32061|Chloroflexia	32061|Chloroflexia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_5539087_2	485913.Krac_0246	9.102e-36	150.0	COG3385@1|root,COG3385@2|Bacteria,2G8GC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CMS3_k127_5541687_0	926569.ANT_04700	1.108e-141	458.0	COG4603@1|root,COG4603@2|Bacteria,2G686@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_5541687_1	926569.ANT_04690	1.42e-133	439.0	COG1079@1|root,COG1079@2|Bacteria,2G6CY@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
CMS3_k127_5553529_2	665571.STHERM_c19260	2.923e-19	90.0	COG0708@1|root,COG0708@2|Bacteria,2J62E@203691|Spirochaetes	203691|Spirochaetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS3_k127_5553529_1	765912.Thimo_2942	8.194e-109	359.0	COG1985@1|root,COG1985@2|Bacteria,1RDMT@1224|Proteobacteria,1S4SQ@1236|Gammaproteobacteria,1X05Z@135613|Chromatiales	135613|Chromatiales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS3_k127_5553529_0	926550.CLDAP_19470	1.668e-114	406.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_5553926_2	1236973.JCM9157_937	2.408e-46	178.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HF8Z@91061|Bacilli,1ZRGY@1386|Bacillus	91061|Bacilli	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
CMS3_k127_5553926_0	926569.ANT_20740	9.603e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5553926_1	926550.CLDAP_05540	9.48e-56	211.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS3_k127_5553926_3	330214.NIDE3360	2.317e-20	106.0	COG0823@1|root,COG0823@2|Bacteria,3J0U9@40117|Nitrospirae	40117|Nitrospirae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_555608_1	926569.ANT_01630	2.301e-31	129.0	2CMS6@1|root,339SN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_555608_0	1305735.JAFT01000005_gene756	3.871e-93	312.0	COG1028@1|root,COG1028@2|Bacteria,1NQJH@1224|Proteobacteria,2UPIA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_5564606_2	479434.Sthe_3403	7.694e-12	72.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CMS3_k127_5564606_0	1278307.KB906968_gene2105	2.798e-99	331.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	linF	-	-	ko:K18236	-	-	-	-	ko00000,ko01504	-	-	-	Adenyl_transf,DUF4037,NTP_transf_2
CMS3_k127_5564606_1	1449076.JOOE01000001_gene3034	1.751e-44	179.0	COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase group 1	treT	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
CMS3_k127_5564606_3	1307759.JOMJ01000003_gene1945	9.411e-08	65.0	COG3307@1|root,COG3307@2|Bacteria,1MYZX@1224|Proteobacteria,42SBB@68525|delta/epsilon subdivisions,2WPTE@28221|Deltaproteobacteria,2M7SK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_5566573_1	926550.CLDAP_09410	5.834e-16	93.0	COG2909@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3899@2|Bacteria,2G80F@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
CMS3_k127_5566573_0	1237149.C900_05711	1.142e-72	258.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_5566573_2	1150621.SMUL_0495	3.735e-06	52.0	COG1522@1|root,COG1522@2|Bacteria,1N0DP@1224|Proteobacteria,42W6I@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
CMS3_k127_5568573_0	101510.RHA1_ro01557	9.056e-36	151.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2GJAR@201174|Actinobacteria,4G9JD@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
CMS3_k127_5568573_1	349741.Amuc_0391	2.12e-14	87.0	COG0739@1|root,COG0739@2|Bacteria,46VAI@74201|Verrucomicrobia,2IU93@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_5584751_3	926550.CLDAP_08020	1.661e-82	287.0	COG3534@1|root,COG3534@2|Bacteria,2G8IC@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
CMS3_k127_5584751_9	983544.Lacal_0762	2.777e-15	91.0	COG4935@1|root,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia	976|Bacteroidetes	O	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
CMS3_k127_5584751_8	1161401.ASJA01000004_gene2303	1.496e-27	131.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,P_proprotein,Peptidase_S8
CMS3_k127_5584751_2	926569.ANT_01870	1.377e-137	445.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS3_k127_5584751_7	1121405.dsmv_1251	7.093e-54	194.0	COG4401@1|root,COG4401@2|Bacteria,1NANV@1224|Proteobacteria,433PN@68525|delta/epsilon subdivisions,2WX99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
CMS3_k127_5584751_6	649638.Trad_0947	2.751e-55	216.0	COG1653@1|root,COG1653@2|Bacteria,1WIKV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027,ko:K17244	ko02010,map02010	M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.40	-	-	SBP_bac_8
CMS3_k127_5584751_5	926569.ANT_11940	8.085e-76	262.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS3_k127_5584751_4	926569.ANT_02900	8.748e-77	267.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS3_k127_5584751_1	1122221.JHVI01000015_gene1704	1.347e-167	533.0	COG1013@1|root,COG1013@2|Bacteria,1WIGM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
CMS3_k127_5584751_0	1122222.AXWR01000014_gene1279	1.054e-256	805.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1WIAF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_5591529_1	153948.NAL212_2839	9.08e-12	76.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	3.1.4.50	ko:K01127	ko00563,map00563	-	R06623	-	ko00000,ko00001,ko01000	-	-	-	Big_5,Calx-beta,FG-GAP,HemolysinCabind
CMS3_k127_5591529_0	102129.Lepto7375DRAFT_5775	5.985e-53	204.0	COG4715@1|root,COG4715@2|Bacteria,1G4AG@1117|Cyanobacteria,1H74H@1150|Oscillatoriales	1117|Cyanobacteria	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS3_k127_5593941_2	326427.Cagg_0684	2.893e-31	129.0	COG1476@1|root,COG3903@1|root,COG1476@2|Bacteria,COG3903@2|Bacteria,2G64X@200795|Chloroflexi,376A5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,NB-ARC,TPR_12
CMS3_k127_5593941_3	72664.XP_006417262.1	3.226e-27	128.0	COG2072@1|root,KOG1399@2759|Eukaryota,37HT9@33090|Viridiplantae,3GCY7@35493|Streptophyta,3HX77@3699|Brassicales	35493|Streptophyta	Q	flavin-containing monooxygenase	-	GO:0001101,GO:0003674,GO:0003824,GO:0004497,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009719,GO:0009725,GO:0009737,GO:0009751,GO:0009753,GO:0009987,GO:0010033,GO:0014070,GO:0016143,GO:0016144,GO:0016491,GO:0019748,GO:0019757,GO:0019758,GO:0019760,GO:0019761,GO:0033993,GO:0042221,GO:0042493,GO:0043436,GO:0044237,GO:0044249,GO:0044272,GO:0044281,GO:0044550,GO:0046677,GO:0050896,GO:0055114,GO:0071704,GO:0097305,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1901700	1.14.13.237	ko:K22324	-	-	-	-	ko00000,ko01000	-	-	-	FMO-like
CMS3_k127_5593941_1	269799.Gmet_2491	1.205e-39	151.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,42QF1@68525|delta/epsilon subdivisions,2WSAA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
CMS3_k127_5593941_0	926550.CLDAP_18870	9.692e-72	256.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_5598478_1	395493.BegalDRAFT_0269	1.747e-104	350.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,1T4BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,Response_reg
CMS3_k127_5598478_0	1128427.KB904821_gene1467	3.165e-172	568.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G0X4@1117|Cyanobacteria,1HI8T@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4
CMS3_k127_5598478_2	1128427.KB904821_gene1466	1.879e-82	284.0	COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria,1HAC9@1150|Oscillatoriales	1117|Cyanobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_560318_5	1499967.BAYZ01000118_gene3266	2.346e-58	220.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_560318_3	179408.Osc7112_2323	6.474e-104	373.0	COG0642@1|root,COG0784@1|root,COG2770@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
CMS3_k127_560318_6	525904.Tter_0922	8.272e-37	148.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_560318_7	471853.Bcav_0186	1.239e-36	143.0	2CEIY@1|root,348HS@2|Bacteria,2H8Z7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_560318_4	1121930.AQXG01000001_gene1036	2.406e-65	238.0	2ES9V@1|root,33JUK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_560318_0	926550.CLDAP_19150	2.242e-164	530.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS3_k127_560318_2	247490.KSU1_C1279	1.383e-126	425.0	COG0535@1|root,COG0535@2|Bacteria,2IZE3@203682|Planctomycetes	203682|Planctomycetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_560318_8	324602.Caur_3820	4.832e-27	126.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_560318_1	1499967.BAYZ01000052_gene4665	5.344e-159	535.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_560342_0	370438.PTH_1739	1.242e-133	438.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_560342_2	1382356.JQMP01000003_gene2208	3.719e-07	61.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi,27YSP@189775|Thermomicrobia	189775|Thermomicrobia	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
CMS3_k127_560342_1	519442.Huta_0424	1.771e-28	123.0	COG0491@1|root,arCOG00504@2157|Archaea,2XWX3@28890|Euryarchaeota,23VD3@183963|Halobacteria	183963|Halobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_5620771_1	926569.ANT_16680	3.126e-123	411.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi	200795|Chloroflexi	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS3_k127_5620771_0	649638.Trad_0654	3.082e-188	597.0	COG0183@1|root,COG0183@2|Bacteria,1WIPU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_5620771_3	179408.Osc7112_6160	1.535e-47	179.0	COG0406@1|root,COG0406@2|Bacteria,1G7MX@1117|Cyanobacteria,1HBV2@1150|Oscillatoriales	1117|Cyanobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS3_k127_5620771_2	1382306.JNIM01000001_gene1173	7.853e-63	229.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS3_k127_5620771_4	1123279.ATUS01000004_gene2834	3.529e-11	66.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1RY5G@1236|Gammaproteobacteria,1J6AH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_5623755_0	502025.Hoch_5119	6.821e-197	628.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS3_k127_5623755_2	502025.Hoch_5120	9.098e-18	91.0	2DUA0@1|root,33PJB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5623755_1	518766.Rmar_1668	8.918e-60	210.0	COG0007@1|root,COG0007@2|Bacteria,4NFVR@976|Bacteroidetes	976|Bacteroidetes	H	Uroporphyrin-III C-methyltransferase	cobA	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CMS3_k127_5632597_0	926569.ANT_19870	5.156e-143	461.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS3_k127_5632597_3	243233.MCA1531	2.818e-12	69.0	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,1SCCQ@1236|Gammaproteobacteria,1XFTW@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS3_k127_5632597_1	926550.CLDAP_24890	4.79e-102	344.0	COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi	200795|Chloroflexi	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS3_k127_5632597_2	765420.OSCT_3068	2.849e-59	218.0	COG2339@1|root,COG2339@2|Bacteria,2G946@200795|Chloroflexi,375Y0@32061|Chloroflexia	32061|Chloroflexia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
CMS3_k127_5639342_6	1122185.N792_02805	0.0001224	53.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1PYUK@1224|Proteobacteria,1S0VV@1236|Gammaproteobacteria,1X5W9@135614|Xanthomonadales	135614|Xanthomonadales	KU	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
CMS3_k127_5639342_1	530564.Psta_1560	3.369e-88	307.0	2EW1S@1|root,33PF1@2|Bacteria,2J1T5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5639342_5	1463926.JOCA01000022_gene6196	3.138e-07	62.0	COG3591@1|root,COG3591@2|Bacteria,2I4IQ@201174|Actinobacteria	201174|Actinobacteria	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_5639342_2	357808.RoseRS_2229	8.298e-62	238.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5639342_4	1298880.AUEV01000013_gene3965	8.931e-11	75.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	afsK	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3,Pkinase
CMS3_k127_5639342_3	357808.RoseRS_3479	7.182e-22	109.0	COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_5639342_0	765420.OSCT_0624	3.786e-177	568.0	COG0664@1|root,COG1234@1|root,COG0664@2|Bacteria,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	MA20_22080	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Lactamase_B_2,TIR-like,cNMP_binding
CMS3_k127_5642352_2	1382356.JQMP01000004_gene227	2.122e-70	242.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_5642352_0	518766.Rmar_0529	3.282e-287	901.0	COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_5642352_1	1521187.JPIM01000062_gene2428	2.667e-73	256.0	COG1319@1|root,COG1319@2|Bacteria,2G60Y@200795|Chloroflexi,3765V@32061|Chloroflexia	32061|Chloroflexia	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_5650932_0	35841.BT1A1_1611	3.24e-189	610.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS3_k127_5650932_2	926550.CLDAP_08060	1.259e-84	286.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS3_k127_5650932_1	1297742.A176_06822	1.615e-91	319.0	COG3361@1|root,COG3361@2|Bacteria	2|Bacteria	S	conserved protein (COG2071)	-	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
CMS3_k127_5652075_5	65497.JODV01000021_gene2130	5.32e-76	276.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4E0AJ@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_5652075_3	1499967.BAYZ01000132_gene305	8.56e-82	284.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_5652075_4	1499967.BAYZ01000132_gene306	4.357e-76	266.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_5652075_1	591019.Shell_1120	5.182e-95	321.0	COG0444@1|root,arCOG00181@2157|Archaea,2XPR3@28889|Crenarchaeota	28889|Crenarchaeota	E	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS3_k127_5652075_0	330084.JNYZ01000005_gene931	5.4e-102	344.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS3_k127_5652075_2	1499967.BAYZ01000077_gene862	4.704e-86	319.0	COG1262@1|root,COG2944@1|root,COG5635@1|root,COG1262@2|Bacteria,COG2944@2|Bacteria,COG5635@2|Bacteria,2NR8B@2323|unclassified Bacteria	2|Bacteria	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,FGE-sulfatase,HTH_3,NACHT,TIR_2
CMS3_k127_5652075_6	1382356.JQMP01000003_gene1359	7.691e-62	229.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_5654772_2	926550.CLDAP_25730	1.107e-59	215.0	COG2721@1|root,COG2721@2|Bacteria,2G8E3@200795|Chloroflexi	200795|Chloroflexi	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	-	-	-	-	-	-	-	-	-	-	GD_AH_C
CMS3_k127_5654772_1	926550.CLDAP_21800	1.466e-99	345.0	COG0524@1|root,COG0524@2|Bacteria,2G6QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS3_k127_5654772_3	583355.Caka_0108	2.796e-49	183.0	COG0800@1|root,COG0800@2|Bacteria,46VG5@74201|Verrucomicrobia,3K7XW@414999|Opitutae	414999|Opitutae	G	2-dehydro-3-deoxyphosphogluconate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
CMS3_k127_5654772_0	1284352.AOIG01000033_gene916	1.003e-141	464.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4HCQC@91061|Bacilli,26TGY@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the formation of D-tagaturonate from D-altronate	uxaB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
CMS3_k127_5654772_4	926550.CLDAP_29610	2.27e-25	106.0	COG1904@1|root,COG1904@2|Bacteria,2G7Q1@200795|Chloroflexi	200795|Chloroflexi	G	Glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
CMS3_k127_5656741_2	694429.Pyrfu_1434	8.168e-58	213.0	COG1131@1|root,arCOG00194@2157|Archaea,2XPS7@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5656741_1	247490.KSU1_C0427	4.684e-64	229.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_5656741_3	926569.ANT_03890	1.805e-27	124.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03890|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5656741_0	309801.trd_0087	5.685e-112	375.0	COG0438@1|root,COG0438@2|Bacteria,2G5QJ@200795|Chloroflexi,27XIG@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_5656741_4	926550.CLDAP_11940	7.1e-20	94.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5657283_0	373994.Riv7116_6502	3.544e-112	369.0	COG2425@1|root,COG2425@2|Bacteria,1G2M9@1117|Cyanobacteria,1HR8F@1161|Nostocales	1117|Cyanobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
CMS3_k127_5657283_1	118168.MC7420_422	8.27e-58	209.0	COG1916@1|root,COG1916@2|Bacteria,1G4FN@1117|Cyanobacteria,1H89R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5658914_0	926550.CLDAP_22510	1.087e-284	882.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS3_k127_5664414_1	1123519.PSJM300_16025	4.724e-46	170.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RRAS@1236|Gammaproteobacteria,1Z04K@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Flavoprotein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS3_k127_5664414_2	118168.MC7420_5995	6.571e-37	152.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
CMS3_k127_5664414_0	1121935.AQXX01000090_gene3857	1.217e-156	512.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1XHA4@135619|Oceanospirillales	135619|Oceanospirillales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_566837_0	1192034.CAP_8618	3.125e-121	398.0	2BVU5@1|root,2Z9FH@2|Bacteria,1R6RV@1224|Proteobacteria,435B2@68525|delta/epsilon subdivisions,2WZN8@28221|Deltaproteobacteria,2Z2ES@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_566837_1	1192034.CAP_8619	1.249e-60	216.0	COG1056@1|root,COG1056@2|Bacteria	2|Bacteria	H	cytidyltransferase-related domain	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,Methyltransf_25
CMS3_k127_5668728_0	861299.J421_0471	2.592e-56	207.0	COG2010@1|root,COG2010@2|Bacteria,1ZUJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5668728_1	479434.Sthe_0104	3.638e-49	188.0	COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi,27YX3@189775|Thermomicrobia	189775|Thermomicrobia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5668728_2	400682.PAC_15711410	5.306e-09	69.0	KOG4287@1|root,KOG4287@2759|Eukaryota	2759|Eukaryota	M	pectin acetylesterase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0008150,GO:0009505,GO:0009506,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0030054,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0052689,GO:0052793,GO:0055044,GO:0071554,GO:0071555,GO:0071840,GO:0071944	3.1.1.98	ko:K14574,ko:K19882	ko03008,ko04310,map03008,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000,ko03009	-	-	-	PAE
CMS3_k127_5671977_0	1121382.JQKG01000001_gene2226	2.735e-67	239.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_5671977_1	1385935.N836_10920	1.305e-44	177.0	COG2334@1|root,COG2334@2|Bacteria,1G3HF@1117|Cyanobacteria,1H9GM@1150|Oscillatoriales	1117|Cyanobacteria	S	homoserine kinase type II (Protein kinase fold)	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5679130_2	1089546.AQUI01000002_gene1020	1.237e-09	65.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,408P2@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5679130_3	1307759.JOMJ01000003_gene1945	2.982e-07	64.0	COG3307@1|root,COG3307@2|Bacteria,1MYZX@1224|Proteobacteria,42SBB@68525|delta/epsilon subdivisions,2WPTE@28221|Deltaproteobacteria,2M7SK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_5679130_4	67267.JNXT01000023_gene4341	0.0006761	53.0	COG1404@1|root,COG3209@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,2I4QJ@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5679130_1	1304872.JAGC01000005_gene1763	1.673e-10	73.0	COG2244@1|root,COG2244@2|Bacteria,1RI9X@1224|Proteobacteria,43B3Z@68525|delta/epsilon subdivisions,2X6HU@28221|Deltaproteobacteria,2MA5D@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_5679130_0	880073.Calab_1748	1.917e-46	171.0	COG2010@1|root,COG2010@2|Bacteria,2NR69@2323|unclassified Bacteria	2|Bacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CMS3_k127_5685785_0	926690.KE386573_gene2677	2.117e-65	233.0	2DZBR@1|root,2N61F@2157|Archaea,2Y570@28890|Euryarchaeota,240NS@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5685785_1	32057.KB217483_gene9468	5.997e-23	114.0	COG1404@1|root,COG1928@1|root,COG1404@2|Bacteria,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109,3.2.1.99	ko:K00728,ko:K06113,ko:K12685	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43,GT39	-	PMT,PMT_4TMC,SLH
CMS3_k127_5685785_3	290317.Cpha266_1048	4.11e-08	66.0	COG1357@1|root,COG1357@2|Bacteria,1FEX7@1090|Chlorobi	1090|Chlorobi	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_5685785_2	1242864.D187_006941	1.614e-12	72.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K06324,ko:K22348,ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_568798_1	1122609.AUGT01000020_gene1126	3.36e-18	98.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4DWWD@85009|Propionibacteriales	201174|Actinobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_569056_4	926550.CLDAP_36920	0.0004135	46.0	29AZZ@1|root,309NJ@2|Bacteria,2G98E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_569056_3	479434.Sthe_2370	5.452e-15	88.0	COG1994@1|root,COG1994@2|Bacteria,2GBF1@200795|Chloroflexi,27Z8Q@189775|Thermomicrobia	189775|Thermomicrobia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_569056_2	1128421.JAGA01000002_gene171	2.018e-35	154.0	COG3428@1|root,COG3428@2|Bacteria,2NS34@2323|unclassified Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	PASTA,bPH_2
CMS3_k127_569056_1	926569.ANT_31550	1.063e-41	161.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS3_k127_569056_0	479434.Sthe_0904	2.229e-59	215.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_569789_0	316274.Haur_0023	1.558e-106	366.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_569789_1	316274.Haur_3451	2.587e-41	158.0	COG2761@1|root,COG2761@2|Bacteria,2G7EP@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_57022_3	926569.ANT_05660	1.764e-38	150.0	COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi	200795|Chloroflexi	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
CMS3_k127_57022_0	1449126.JQKL01000004_gene620	3.223e-141	460.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2689E@186813|unclassified Clostridiales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS3_k127_57022_2	309801.trd_0578	1.674e-76	260.0	COG2080@1|root,COG2080@2|Bacteria,2GBQV@200795|Chloroflexi,27Y9S@189775|Thermomicrobia	189775|Thermomicrobia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_57022_1	196490.AUEZ01000042_gene7229	4.153e-86	295.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JUB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_5702992_1	530564.Psta_0724	1.384e-48	183.0	COG1994@1|root,COG1994@2|Bacteria,2J0CK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_5702992_0	1183438.GKIL_1904	2.478e-102	337.0	COG0745@1|root,COG0745@2|Bacteria,1G16W@1117|Cyanobacteria	1117|Cyanobacteria	K	Two component transcriptional regulator, Winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5706644_1	926550.CLDAP_30040	1.04e-60	217.0	COG0642@1|root,COG2205@2|Bacteria	926550.CLDAP_30040|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5706644_0	1128421.JAGA01000001_gene2454	5.643e-65	231.0	COG0745@1|root,COG0745@2|Bacteria,2NQZN@2323|unclassified Bacteria	2|Bacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5706644_2	1463900.JOIX01000063_gene2825	2.414e-07	61.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase M50B family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
CMS3_k127_5715736_2	926560.KE387023_gene2132	1.012e-65	237.0	COG4587@1|root,COG4587@2|Bacteria,1WMG7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
CMS3_k127_5715736_0	926560.KE387023_gene2133	7.431e-149	480.0	COG4586@1|root,COG4586@2|Bacteria,1WM9A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_5715736_1	1499967.BAYZ01000171_gene5534	4.203e-90	318.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
CMS3_k127_5715736_5	1463917.JODC01000005_gene6610	4.608e-12	74.0	COG1670@1|root,COG1670@2|Bacteria,2HH6S@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_5715736_3	1128421.JAGA01000002_gene1835	2.634e-55	202.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_5715736_4	329726.AM1_1562	1.191e-14	87.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
CMS3_k127_57321_0	479434.Sthe_2775	2.578e-73	260.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2G88Z@200795|Chloroflexi,27YSQ@189775|Thermomicrobia	189775|Thermomicrobia	O	metallochaperone-like domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
CMS3_k127_57321_3	1278073.MYSTI_05419	3.078e-11	64.0	COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,437ER@68525|delta/epsilon subdivisions,2X2M0@28221|Deltaproteobacteria,2Z09K@29|Myxococcales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_57321_2	485913.Krac_6522	1.828e-17	87.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_57321_1	266117.Rxyl_2944	6.445e-40	153.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,4CQKV@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_573658_5	926569.ANT_28810	1.692e-51	186.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
CMS3_k127_573658_3	926569.ANT_28810	6.836e-100	331.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
CMS3_k127_573658_0	867845.KI911784_gene3194	1.128e-146	477.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi,375AX@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
CMS3_k127_573658_9	1522072.IL54_3864	4.946e-11	75.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales	204457|Sphingomonadales	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS3_k127_573658_8	47839.CCAU010000016_gene4517	7.441e-15	87.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,236F7@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
CMS3_k127_573658_6	525904.Tter_1099	1.213e-41	174.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_573658_11	118166.JH976537_gene19	0.0001486	52.0	COG0392@1|root,COG0392@2|Bacteria,1GAD9@1117|Cyanobacteria,1HDT1@1150|Oscillatoriales	1117|Cyanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_573658_1	1385935.N836_09965	1.622e-145	494.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_573658_10	1273538.G159_04940	5.33e-10	64.0	2DNVA@1|root,32ZBE@2|Bacteria,1W480@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_573658_4	309807.SRU_0260	8.799e-94	325.0	COG0815@1|root,COG0815@2|Bacteria,4NMJK@976|Bacteroidetes	976|Bacteroidetes	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_573658_7	383372.Rcas_0169	1.44e-28	128.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Spermine_synth
CMS3_k127_573658_2	1382306.JNIM01000001_gene479	7.669e-135	448.0	COG2352@1|root,COG2352@2|Bacteria,2G62H@200795|Chloroflexi	200795|Chloroflexi	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS3_k127_5738531_1	697281.Mahau_0316	7.59e-183	580.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_5738531_0	469383.Cwoe_1088	8.64e-205	645.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CPID@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_5738531_3	1499967.BAYZ01000074_gene2132	3.719e-65	229.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS3_k127_5738531_2	1499967.BAYZ01000074_gene2134	3.553e-143	459.0	COG0320@1|root,COG0320@2|Bacteria,2NNPI@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS3_k127_5760049_3	290315.Clim_1053	2.352e-18	98.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
CMS3_k127_5760049_1	991905.SL003B_2714	1.394e-76	264.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TVZ2@28211|Alphaproteobacteria,4BQZC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Ndr family	pcaD	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,CMD
CMS3_k127_5760049_0	935866.JAER01000011_gene2188	6.778e-77	272.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria,4DWK2@85009|Propionibacteriales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_5760049_2	1121028.ARQE01000006_gene4484	9.544e-66	235.0	COG1802@1|root,COG1802@2|Bacteria,1NWSI@1224|Proteobacteria,2TTXQ@28211|Alphaproteobacteria,2PM9V@255475|Aurantimonadaceae	28211|Alphaproteobacteria	K	FCD	MA20_45020	-	-	ko:K11475	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
CMS3_k127_5764995_3	1382306.JNIM01000001_gene2755	1.592e-15	79.0	COG1335@1|root,COG1335@2|Bacteria,2G8KH@200795|Chloroflexi	200795|Chloroflexi	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5764995_4	1499680.CCFE01000021_gene2287	1.144e-10	71.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,4HF1T@91061|Bacilli,1ZFJ2@1386|Bacillus	91061|Bacilli	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_3,VWA_CoxE
CMS3_k127_5764995_0	867845.KI911784_gene3619	2.606e-188	596.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi,375C2@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS3_k127_5764995_2	515635.Dtur_0748	5.377e-70	263.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	saeS	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02484,ko:K07636,ko:K10681,ko:K10819,ko:K18350,ko:K20487	ko00230,ko01502,ko02020,ko02024,ko02025,ko04113,ko04213,map00230,map01502,map02020,map02024,map02025,map04113,map04213	M00434,M00468,M00652,M00657,M00695,M00816	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_5764995_1	1382306.JNIM01000001_gene2607	2.169e-110	370.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_5770442_1	1265505.ATUG01000002_gene1060	7.371e-63	221.0	COG0834@1|root,COG5000@1|root,COG0834@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_5770442_2	1121904.ARBP01000014_gene142	1.862e-47	179.0	arCOG07533@1|root,2ZF5I@2|Bacteria,4NS85@976|Bacteroidetes,47X6K@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
CMS3_k127_5770442_0	42256.RradSPS_0358	5.084e-293	925.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_5770442_3	1303518.CCALI_01379	7.206e-25	122.0	COG1413@1|root,COG2211@1|root,COG1413@2|Bacteria,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	3.4.11.2	ko:K01256,ko:K16210	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko02000	2.A.2.5	-	-	HEAT_2,MFS_1
CMS3_k127_5775926_0	1279009.ADICEAN_01425	1.072e-27	123.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_5775926_1	1236902.ANAS01000006_gene5175	1.77e-19	96.0	COG3675@1|root,COG3675@2|Bacteria,2GND0@201174|Actinobacteria	201174|Actinobacteria	I	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CMS3_k127_5780140_0	1440053.JOEI01000003_gene4179	0.0002714	54.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,Trans_reg_C
CMS3_k127_5785338_2	485913.Krac_6522	2.089e-27	115.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_5785338_1	357808.RoseRS_1483	5.94e-108	357.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,375BG@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS3_k127_5785338_0	1499967.BAYZ01000052_gene4665	7.375e-162	541.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_5791240_1	266117.Rxyl_2946	1.173e-103	372.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS3_k127_5791240_3	251221.35211658	6.69e-43	181.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,Trans_reg_C
CMS3_k127_5791240_4	1034769.KB910518_gene4348	3.385e-19	94.0	2BZS9@1|root,2ZC3V@2|Bacteria,1V250@1239|Firmicutes,4HB76@91061|Bacilli,26T3E@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_5791240_2	369723.Strop_1867	3.12e-75	270.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4D92K@85008|Micromonosporales	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_5791240_0	1173024.KI912148_gene4061	2.265e-163	529.0	COG2303@1|root,COG2303@2|Bacteria,1FZYZ@1117|Cyanobacteria,1JJ6F@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_5798720_8	1148.1653140	1.486e-76	265.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_5798720_2	41431.PCC8801_0047	3.616e-135	436.0	COG1216@1|root,COG1216@2|Bacteria,1GIT7@1117|Cyanobacteria,3KK6J@43988|Cyanothece	1117|Cyanobacteria	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5798720_4	1121440.AUMA01000002_gene2107	1.389e-97	324.0	COG1083@1|root,COG1083@2|Bacteria,1RHF3@1224|Proteobacteria,42XE9@68525|delta/epsilon subdivisions,2WXAN@28221|Deltaproteobacteria,2MBP9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
CMS3_k127_5798720_3	1121440.AUMA01000002_gene2106	1.734e-129	420.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,2M9D7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_5798720_7	1148.1653145	2.25e-77	267.0	COG1028@1|root,COG1028@2|Bacteria,1G2YY@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_5798720_6	926569.ANT_06530	8.383e-84	285.0	COG2604@1|root,COG2604@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,DUF2920,MAF_flag10
CMS3_k127_5798720_10	592029.DDD_2273	6.528e-54	200.0	2EWJQ@1|root,33PXW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5798720_12	1048339.KB913029_gene5007	6.831e-41	165.0	COG0615@1|root,COG0615@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_5798720_9	1238182.C882_1606	3.377e-61	226.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria,2JRK0@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
CMS3_k127_5798720_1	926550.CLDAP_10360	6.423e-161	554.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,2G81B@200795|Chloroflexi	200795|Chloroflexi	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Wzy_C
CMS3_k127_5798720_5	383372.Rcas_0017	3.1e-88	302.0	COG0472@1|root,COG0472@2|Bacteria,2G7WQ@200795|Chloroflexi,375BA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS3_k127_5798720_11	926550.CLDAP_40550	3.532e-53	196.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
CMS3_k127_5798720_0	485913.Krac_8955	2.305e-180	574.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_5800211_1	211165.AJLN01000035_gene2730	2.387e-66	239.0	COG1073@1|root,COG1073@2|Bacteria,1G9XB@1117|Cyanobacteria	1117|Cyanobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_5800211_0	926550.CLDAP_25210	2.697e-86	297.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS3_k127_5803524_0	1122221.JHVI01000005_gene596	3.701e-88	295.0	COG0714@1|root,COG0714@2|Bacteria,1WKZZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS3_k127_5803524_2	709986.Deima_2986	3.187e-07	61.0	COG0824@1|root,COG0824@2|Bacteria,1WKH6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_5803524_1	1128421.JAGA01000002_gene1212	7.452e-25	111.0	COG3552@1|root,COG3552@2|Bacteria,2NQE1@2323|unclassified Bacteria	2|Bacteria	S	VWA domain containing CoxE-like protein	coxE	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS3_k127_5805437_2	485913.Krac_10314	5.69e-61	224.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
CMS3_k127_5805437_1	479434.Sthe_2033	1.728e-95	327.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5805437_3	926550.CLDAP_36240	6.136e-48	193.0	COG3307@1|root,COG4783@1|root,COG3307@2|Bacteria,COG4783@2|Bacteria,2G9NN@200795|Chloroflexi	200795|Chloroflexi	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_5805437_0	56110.Oscil6304_3528	3.604e-120	394.0	COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1H7R6@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_5814919_0	926569.ANT_30140	1.31e-233	728.0	COG1486@1|root,COG1486@2|Bacteria,2G7VR@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS3_k127_5814919_12	247490.KSU1_B0185	0.0002902	47.0	COG2846@1|root,COG2846@2|Bacteria,2J23U@203682|Planctomycetes	203682|Planctomycetes	D	NnrS protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,NnrS
CMS3_k127_5814919_1	552811.Dehly_1516	7.629e-189	622.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi	200795|Chloroflexi	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_5814919_3	526225.Gobs_2177	1.881e-119	398.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4EWFM@85013|Frankiales	201174|Actinobacteria	V	Beta-lactamase	nylB	-	3.5.1.46	ko:K01453	ko00930,ko01120,map00930,map01120	-	R00059,R10975,R10979	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	Beta-lactamase
CMS3_k127_5814919_6	861299.J421_0471	9.236e-68	244.0	COG2010@1|root,COG2010@2|Bacteria,1ZUJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5814919_4	1318628.MARLIPOL_06974	2.16e-83	282.0	COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,1SXIM@1236|Gammaproteobacteria,46ATA@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_5814919_9	500153.JOEK01000009_gene5176	2.734e-20	94.0	2ER8X@1|root,33IUI@2|Bacteria,2IRAS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
CMS3_k127_5814919_5	1192034.CAP_4066	5.833e-68	252.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
CMS3_k127_5814919_2	926550.CLDAP_19470	3.278e-131	459.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_5814919_7	765420.OSCT_2504	4.621e-44	172.0	COG0454@1|root,COG0456@2|Bacteria,2G8DV@200795|Chloroflexi,377HZ@32061|Chloroflexia	32061|Chloroflexia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_5814919_11	555079.Toce_0676	3.297e-05	55.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	3.4.11.19	ko:K01266,ko:K07052	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abi
CMS3_k127_5814919_10	1521187.JPIM01000029_gene1560	2.138e-11	69.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8QT@200795|Chloroflexi,376YD@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
CMS3_k127_5815297_1	1122221.JHVI01000007_gene2170	2.77e-45	173.0	COG4101@1|root,COG4101@2|Bacteria	2|Bacteria	G	3-hydroxyanthranilate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_5815297_0	330084.JNYZ01000033_gene5642	1.367e-115	383.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4DZDK@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	yajO	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS3_k127_5819125_2	216595.PFLU_1891	9.149e-07	62.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria	1224|Proteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
CMS3_k127_5819125_0	1089545.KB913037_gene8329	7.409e-36	157.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria,4DZJQ@85010|Pseudonocardiales	201174|Actinobacteria	P	CopC domain	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
CMS3_k127_5819125_1	1382356.JQMP01000003_gene1492	5.837e-25	112.0	arCOG08811@1|root,32UTS@2|Bacteria,2G8VM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5819389_1	926550.CLDAP_03710	3.659e-88	298.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS3_k127_5819389_2	1128421.JAGA01000002_gene405	2.399e-27	121.0	2EV3Q@1|root,33NIR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5819389_3	867903.ThesuDRAFT_00702	1.338e-13	74.0	COG1308@1|root,COG1308@2|Bacteria,1V7I9@1239|Firmicutes,24M6Q@186801|Clostridia,3WDGX@538999|Clostridiales incertae sedis	186801|Clostridia	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
CMS3_k127_5819389_4	926560.KE387023_gene1958	5.082e-12	74.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5819389_0	357808.RoseRS_0928	3.894e-116	384.0	COG0003@1|root,COG0003@2|Bacteria,2G64V@200795|Chloroflexi,375AR@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CMS3_k127_5832466_1	511062.GU3_06040	1.546e-145	473.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1Y3SI@135624|Aeromonadales	135624|Aeromonadales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS3_k127_5832466_3	1123057.P872_12160	5.68e-48	184.0	2EZ5S@1|root,33SBU@2|Bacteria,4NZY3@976|Bacteroidetes,47U0G@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5832466_0	861299.J421_2874	2.705e-156	506.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
CMS3_k127_5832466_5	96561.Dole_1755	4.5e-15	87.0	COG0454@1|root,COG0456@2|Bacteria,1NHTY@1224|Proteobacteria,43BRD@68525|delta/epsilon subdivisions,2WN1I@28221|Deltaproteobacteria,2MJQH@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF4915)	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF4915
CMS3_k127_5832466_4	765420.OSCT_2357	1.024e-19	92.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	mrx1	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
CMS3_k127_5832466_2	926550.CLDAP_30950	2e-54	198.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS3_k127_5835169_4	266264.Rmet_4371	2.097e-08	57.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,2VNP3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Hydrolase_4
CMS3_k127_5835169_1	2002.JOEQ01000050_gene8399	6.332e-58	207.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria,4EP20@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5835169_2	649638.Trad_0489	7.853e-45	170.0	COG0702@1|root,COG0702@2|Bacteria,1WKA0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS3_k127_5835169_0	526227.Mesil_0256	3.722e-90	312.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
CMS3_k127_5836402_5	309801.trd_0089	1.695e-13	73.0	COG0227@1|root,COG0227@2|Bacteria,2G9W5@200795|Chloroflexi,27Z9I@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal L28 family	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS3_k127_5836402_4	926569.ANT_15240	1.792e-25	109.0	COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
CMS3_k127_5836402_1	1382306.JNIM01000001_gene214	3.034e-138	459.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
CMS3_k127_5836402_2	555079.Toce_1054	3.237e-43	168.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,42GID@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM degV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
CMS3_k127_5836402_0	926550.CLDAP_35850	3.149e-217	703.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS3_k127_5836402_3	926569.ANT_15280	5.831e-36	139.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_5852310_0	316274.Haur_3926	2.551e-91	319.0	COG2304@1|root,COG3087@1|root,COG5426@1|root,COG2304@2|Bacteria,COG3087@2|Bacteria,COG5426@2|Bacteria,2GBRR@200795|Chloroflexi,376B2@32061|Chloroflexia	32061|Chloroflexia	D	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_2
CMS3_k127_5852310_1	1094980.Mpsy_1174	1.931e-19	104.0	COG0642@1|root,COG2203@1|root,arCOG02339@1|root,arCOG02376@1|root,arCOG03567@1|root,arCOG02339@2157|Archaea,arCOG02357@2157|Archaea,arCOG02376@2157|Archaea,arCOG03567@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,2NBNI@224756|Methanomicrobia	28890|Euryarchaeota	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_9,sCache_3_3
CMS3_k127_5853312_3	926550.CLDAP_31770	0.0009325	46.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5853312_1	926550.CLDAP_12670	2.273e-114	385.0	COG3307@1|root,COG3307@2|Bacteria,2G6B1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_5853312_2	326427.Cagg_1699	2.107e-09	64.0	COG1388@1|root,COG1388@2|Bacteria,2G99N@200795|Chloroflexi,375X0@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_5853312_0	926569.ANT_04530	4.137e-149	481.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
CMS3_k127_5868827_3	926569.ANT_02380	1.367e-117	385.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS3_k127_5868827_6	1009370.ALO_07128	2.32e-29	122.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H3DN@909932|Negativicutes	909932|Negativicutes	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5868827_4	32049.SYNPCC7002_A2397	7.184e-64	229.0	COG1235@1|root,COG1235@2|Bacteria,1G1UR@1117|Cyanobacteria,1GZKA@1129|Synechococcus	1117|Cyanobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS3_k127_5868827_1	204669.Acid345_1270	3.698e-241	754.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
CMS3_k127_5868827_2	1123073.KB899241_gene2287	4.472e-129	424.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales	135614|Xanthomonadales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
CMS3_k127_5868827_5	926569.ANT_16430	9.648e-42	157.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5868827_0	344747.PM8797T_12503	5.959e-283	880.0	COG0129@1|root,COG0129@2|Bacteria,2IWXV@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS3_k127_5869941_4	926569.ANT_29030	5.911e-25	105.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS3_k127_5869941_0	926569.ANT_25700	9.816e-197	661.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_5869941_1	926550.CLDAP_01930	7.228e-65	248.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS3_k127_5869941_3	1128421.JAGA01000003_gene3738	2.973e-37	161.0	COG4745@1|root,COG4745@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5869941_2	926550.CLDAP_11940	1.103e-38	165.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5872822_2	765420.OSCT_3223	1.913e-58	214.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,374XI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
CMS3_k127_5872822_0	926569.ANT_09890	1.052e-152	512.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_5872822_1	383372.Rcas_2015	1.315e-74	261.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3757Z@32061|Chloroflexia	32061|Chloroflexia	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_5875273_1	324602.Caur_0486	1.047e-54	221.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_5875273_0	1128421.JAGA01000003_gene3678	1.024e-68	267.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS3_k127_5875273_2	1370121.AUWS01000062_gene3875	9.476e-17	84.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,Guanylate_cyc,NB-ARC
CMS3_k127_5879585_13	710686.Mycsm_02859	2.313e-09	58.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,Guanylate_cyc,NB-ARC
CMS3_k127_5879585_6	926560.KE387023_gene3595	3.159e-73	281.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS3_k127_5879585_9	1121468.AUBR01000005_gene40	4.237e-41	176.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_5879585_11	33876.JNXY01000026_gene3363	1.519e-36	149.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DBPZ@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_5879585_12	1541065.JRFE01000014_gene1178	8.646e-30	123.0	COG5207@1|root,COG5207@2|Bacteria,1G7WG@1117|Cyanobacteria	1117|Cyanobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
CMS3_k127_5879585_10	1122915.AUGY01000083_gene4478	1.485e-36	161.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,1U0F2@1239|Firmicutes,4I9SK@91061|Bacilli,271XT@186822|Paenibacillaceae	91061|Bacilli	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_5879585_0	765420.OSCT_1980	4.007e-157	518.0	COG5316@1|root,COG5316@2|Bacteria,2GBUR@200795|Chloroflexi,375C5@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5879585_8	926569.ANT_20000	1.93e-48	179.0	COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi	200795|Chloroflexi	E	Histidinol-phosphate phosphatase family protein	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glycos_transf_2,Hydrolase_like
CMS3_k127_5879585_4	926569.ANT_20380	1.933e-120	407.0	COG0489@1|root,COG3206@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,COG3944@2|Bacteria,2G5WM@200795|Chloroflexi	2|Bacteria	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,DUF2325,GNVR,Wzz
CMS3_k127_5879585_7	926569.ANT_15770	3.126e-62	219.0	COG0279@1|root,COG2203@1|root,COG0279@2|Bacteria,COG2203@2|Bacteria,2G6QD@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS3_k127_5879585_1	926569.ANT_19990	4.3e-133	436.0	COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM GHMP kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_5879585_3	926569.ANT_15830	7.994e-124	404.0	COG1087@1|root,COG1087@2|Bacteria,2GA96@200795|Chloroflexi	200795|Chloroflexi	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_5879585_2	357808.RoseRS_1134	5.577e-132	437.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G67F@200795|Chloroflexi,3769D@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_5879585_5	926569.ANT_20360	2.403e-95	325.0	COG0438@1|root,COG0438@2|Bacteria,2G60E@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_5891499_1	926550.CLDAP_37770	3e-17	93.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G852@200795|Chloroflexi	200795|Chloroflexi	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_5891499_0	945713.IALB_0216	6.157e-63	235.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5891640_2	1123401.JHYQ01000045_gene3373	3.986e-91	320.0	28J2S@1|root,2Z8Z4@2|Bacteria,1NQU2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5891640_3	1123401.JHYQ01000045_gene3373	8.771e-91	321.0	28J2S@1|root,2Z8Z4@2|Bacteria,1NQU2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5891640_1	1341181.FLJC2902T_10660	3.546e-103	350.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia,2P01U@237|Flavobacterium	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
CMS3_k127_5891640_0	869210.Marky_0500	2.554e-126	419.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_5891640_4	644966.Tmar_1299	2.423e-53	192.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WD3X@538999|Clostridiales incertae sedis	186801|Clostridia	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_5895222_0	1128421.JAGA01000002_gene1135	6.261e-241	754.0	COG1884@1|root,COG1884@2|Bacteria,2NNZ9@2323|unclassified Bacteria	2|Bacteria	I	Methylmalonyl-CoA mutase	icmA	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS3_k127_5895379_0	1121438.JNJA01000023_gene372	4.476e-101	341.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42ZMZ@68525|delta/epsilon subdivisions,2X27A@28221|Deltaproteobacteria,2M8TC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5895379_2	926569.ANT_29550	2.246e-46	186.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_5895379_8	485913.Krac_8809	8.935e-07	62.0	COG1716@1|root,COG1716@2|Bacteria,2G8U3@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA
CMS3_k127_5895379_9	1150864.MILUP08_41475	9.669e-05	54.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHU_C,GSDH,PKD,ThuA
CMS3_k127_5895379_3	926550.CLDAP_35480	4.802e-25	123.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
CMS3_k127_5895379_4	357808.RoseRS_1670	2.334e-23	117.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1,3.2.1.50	ko:K01205,ko:K07004,ko:K12132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko04147	-	-	-	DUF3662,DUF916,FHA,NAGLU,NAGLU_C,NAGLU_N,Yop-YscD_cpl
CMS3_k127_5895379_5	525246.HMPREF0058_2228	2.627e-12	81.0	COG0739@1|root,COG0739@2|Bacteria,2GM7Q@201174|Actinobacteria,4D81C@85005|Actinomycetales	201174|Actinobacteria	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_5895379_6	497964.CfE428DRAFT_1740	2.186e-10	74.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
CMS3_k127_5895379_7	391625.PPSIR1_10130	8.941e-08	65.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_5895379_1	926569.ANT_19800	1.261e-93	334.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900479_3	945713.IALB_0509	4.122e-62	226.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
CMS3_k127_5900479_1	765420.OSCT_2093	1.725e-97	337.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
CMS3_k127_5900479_0	385682.AFSL01000102_gene55	7.42e-196	624.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
CMS3_k127_5900479_2	485913.Krac_6300	6.991e-85	292.0	COG0524@1|root,COG0524@2|Bacteria,2G9R5@200795|Chloroflexi	200795|Chloroflexi	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_5905689_5	688245.CtCNB1_1735	1.018e-45	169.0	COG5113@1|root,COG3236@2|Bacteria,1RCXE@1224|Proteobacteria,2VRRD@28216|Betaproteobacteria,4AE7G@80864|Comamonadaceae	28216|Betaproteobacteria	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
CMS3_k127_5905689_10	1128421.JAGA01000003_gene2863	1.187e-05	53.0	COG1285@1|root,COG1285@2|Bacteria,2NPSV@2323|unclassified Bacteria	2|Bacteria	S	MgtC family	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_5905689_9	1128421.JAGA01000003_gene2863	1.094e-05	48.0	COG1285@1|root,COG1285@2|Bacteria,2NPSV@2323|unclassified Bacteria	2|Bacteria	S	MgtC family	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS3_k127_5905689_4	292415.Tbd_1210	3.018e-59	209.0	COG4333@1|root,COG4333@2|Bacteria,1N19M@1224|Proteobacteria,2VVXJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1643)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1643
CMS3_k127_5905689_1	118161.KB235922_gene5485	3.227e-120	398.0	COG1404@1|root,COG1404@2|Bacteria,1G3YQ@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_5905689_0	1242864.D187_003111	7.867e-134	465.0	COG1672@1|root,COG1672@2|Bacteria,1PIY1@1224|Proteobacteria,433X5@68525|delta/epsilon subdivisions,2X3YJ@28221|Deltaproteobacteria,2YXMA@29|Myxococcales	28221|Deltaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
CMS3_k127_5905689_8	1172188.KB911826_gene213	1.419e-08	66.0	2DCV8@1|root,2ZFG2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5905689_2	489825.LYNGBM3L_46770	1.081e-79	280.0	COG3591@1|root,COG3591@2|Bacteria,1G4N7@1117|Cyanobacteria,1HCM7@1150|Oscillatoriales	1117|Cyanobacteria	E	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_5905689_3	63737.Npun_R5185	6.893e-73	263.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
CMS3_k127_5905689_7	1183438.GKIL_2486	5.635e-19	93.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5905689_6	13689.BV96_02858	2.364e-19	98.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_5908821_1	525309.HMPREF0494_0516	1.519e-27	121.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,3F4XJ@33958|Lactobacillaceae	91061|Bacilli	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.2.1.17	ko:K01185,ko:K02395,ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	CBM50	-	Glucosaminidase,LysM
CMS3_k127_5908821_0	926569.ANT_00050	1.327e-124	413.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_5911242_1	1123276.KB893255_gene1852	2.631e-07	64.0	COG1577@1|root,COG4886@1|root,COG4935@1|root,COG1577@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria,4PPHP@976|Bacteroidetes,47YR0@768503|Cytophagia	976|Bacteroidetes	IO	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,P_proprotein
CMS3_k127_5911242_0	1396.DJ87_2608	1.692e-61	235.0	COG3227@1|root,COG3227@2|Bacteria,1TSGU@1239|Firmicutes,4HC7W@91061|Bacilli	91061|Bacilli	E	Peptidase M36	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PepSY,Peptidase_M36
CMS3_k127_5914137_1	44056.XP_009035154.1	3.361e-17	96.0	KOG4287@1|root,KOG4287@2759|Eukaryota	2759|Eukaryota	M	pectin acetylesterase activity	-	-	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_5914137_2	1713.JOFV01000005_gene2375	7.165e-14	83.0	2DNX8@1|root,32ZMU@2|Bacteria,2IR05@201174|Actinobacteria,4F2S4@85016|Cellulomonadaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5914137_0	485913.Krac_8942	2.279e-83	290.0	COG2141@1|root,COG2141@2|Bacteria,2G8CA@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_5914137_3	565034.BHWA1_01724	2.702e-09	70.0	COG0739@1|root,COG0739@2|Bacteria,2J5SN@203691|Spirochaetes	203691|Spirochaetes	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_5923508_3	65393.PCC7424_5763	1.399e-64	226.0	COG1132@1|root,COG1132@2|Bacteria,1G0Q1@1117|Cyanobacteria,3KJ4A@43988|Cyanothece	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_5923508_4	324057.Pjdr2_4007	1.412e-58	211.0	COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli,2766F@186822|Paenibacillaceae	91061|Bacilli	S	HAD-hyrolase-like	yfnB	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_5923508_0	313624.NSP_2760	5.71e-173	562.0	COG1132@1|root,COG1132@2|Bacteria,1G1QS@1117|Cyanobacteria,1HS1R@1161|Nostocales	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_5923508_1	292459.STH1427	9.252e-146	482.0	COG1132@1|root,COG1132@2|Bacteria,1UZA0@1239|Firmicutes,24DXZ@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_5923508_2	316274.Haur_1458	6.841e-90	334.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3766E@32061|Chloroflexia	32061|Chloroflexia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
CMS3_k127_5926358_0	1173023.KE650771_gene5342	2.397e-150	503.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1JJJW@1189|Stigonemataceae	1117|Cyanobacteria	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
CMS3_k127_5937149_0	1382306.JNIM01000001_gene3371	3.83e-79	280.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CMS3_k127_5937149_1	479434.Sthe_3365	1.059e-70	246.0	COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi,27YZ8@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5937149_2	1499967.BAYZ01000120_gene3420	2.526e-11	64.0	COG2020@1|root,COG2020@2|Bacteria,2NR07@2323|unclassified Bacteria	2|Bacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_5939624_8	477641.MODMU_3479	1.263e-16	86.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4ERJ2@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_5939624_6	1408424.JHYI01000013_gene1018	4.735e-27	125.0	COG0477@1|root,COG2814@2|Bacteria,1V9VP@1239|Firmicutes,4HX3Y@91061|Bacilli,1ZS7H@1386|Bacillus	91061|Bacilli	EGP	Major Facilitator Superfamily	yjbB	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5939624_7	644076.SCH4B_0009	7.766e-23	107.0	2DMRI@1|root,32T77@2|Bacteria,1R79W@1224|Proteobacteria,2VGIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
CMS3_k127_5939624_3	1380394.JADL01000007_gene4518	3.884e-59	212.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2U3WT@28211|Alphaproteobacteria,2JZEP@204441|Rhodospirillales	204441|Rhodospirillales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS3_k127_5939624_0	1499967.BAYZ01000060_gene6002	6.626e-164	542.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
CMS3_k127_5939624_5	1469607.KK073769_gene5782	4.896e-33	141.0	COG5126@1|root,COG5126@2|Bacteria,1G7DT@1117|Cyanobacteria	1117|Cyanobacteria	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,EF-hand_7
CMS3_k127_5939624_10	1075090.GOAMR_19_00600	1.132e-09	70.0	2DMG6@1|root,32RB5@2|Bacteria,2GMQI@201174|Actinobacteria,4GAMP@85026|Gordoniaceae	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
CMS3_k127_5939624_9	926550.CLDAP_22130	4.076e-11	68.0	COG1051@1|root,COG1051@2|Bacteria,2G7HA@200795|Chloroflexi	200795|Chloroflexi	F	PFAM NUDIX hydrolase	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_5939624_1	1313172.YM304_10890	1.816e-130	431.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,4CNKK@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_5939624_2	868595.Desca_2132	1.001e-59	218.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,260PT@186807|Peptococcaceae	186801|Clostridia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_5939624_4	485913.Krac_5098	6.144e-38	147.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS3_k127_5951017_0	1286631.X805_22920	6.575e-79	291.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KKC9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_5951017_2	1392502.JNIO01000008_gene1855	7.88e-29	128.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS3_k127_5951017_3	765420.OSCT_0023	1.683e-25	113.0	COG3023@1|root,COG3209@1|root,COG3023@2|Bacteria,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2,PG_binding_1
CMS3_k127_5951017_1	316274.Haur_2280	6.887e-54	203.0	2ARN4@1|root,31GYT@2|Bacteria,2G9ZH@200795|Chloroflexi,377IG@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5951017_4	56110.Oscil6304_3559	4.013e-09	71.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
CMS3_k127_5951211_9	511051.CSE_06740	0.0009174	44.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,YARHG,zinc_ribbon_2
CMS3_k127_5951211_4	926550.CLDAP_04440	1.27e-48	179.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi	200795|Chloroflexi	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS3_k127_5951211_3	926550.CLDAP_11930	7.828e-51	205.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,PTPS_related
CMS3_k127_5951211_1	926550.CLDAP_18020	1.769e-135	437.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS3_k127_5951211_0	926569.ANT_20580	1.536e-150	484.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS3_k127_5951211_5	926550.CLDAP_30130	2.259e-40	154.0	2BX7X@1|root,336E6@2|Bacteria,2G9KF@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5951211_6	555088.DealDRAFT_3156	4.734e-23	116.0	COG0739@1|root,COG0739@2|Bacteria,1V32Q@1239|Firmicutes,251MP@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_5951211_8	383372.Rcas_3329	2.174e-17	97.0	COG2866@1|root,COG2866@2|Bacteria,2GB4F@200795|Chloroflexi,3751R@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_5951211_2	926550.CLDAP_19600	3.414e-95	323.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS3_k127_5951211_7	926554.KI912669_gene4972	1.195e-17	88.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_5959461_8	1128421.JAGA01000003_gene3091	5.402e-12	77.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_5959461_5	926550.CLDAP_24630	2.435e-23	113.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_5959461_2	926569.ANT_13070	2.55e-62	223.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS3_k127_5959461_3	926550.CLDAP_39470	1.433e-27	124.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_5959461_7	1121861.KB899941_gene3860	3.704e-18	96.0	COG0454@1|root,COG0456@2|Bacteria,1N6RY@1224|Proteobacteria,2TSVU@28211|Alphaproteobacteria,2JUFP@204441|Rhodospirillales	204441|Rhodospirillales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
CMS3_k127_5959461_0	926550.CLDAP_24610	6.438e-144	467.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS3_k127_5959461_9	344747.PM8797T_11154	1.301e-06	50.0	2E58P@1|root,33013@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5959461_1	867845.KI911784_gene1315	1.873e-136	446.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,376G2@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_5959461_6	1434325.AZQN01000004_gene1883	3.327e-23	110.0	COG1807@1|root,COG1807@2|Bacteria,4NG1F@976|Bacteroidetes,47NSA@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_5959461_4	1123277.KB893175_gene1373	1.309e-24	117.0	COG1807@1|root,COG1807@2|Bacteria,4NG1F@976|Bacteroidetes,47NSA@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_5962844_2	357808.RoseRS_2058	7.918e-91	315.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,2G7T5@200795|Chloroflexi,376H4@32061|Chloroflexia	32061|Chloroflexia	P	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS3_k127_5962844_8	1200792.AKYF01000010_gene2349	5.904e-06	56.0	COG3393@1|root,COG3393@2|Bacteria,1V9KV@1239|Firmicutes,4HJ79@91061|Bacilli,26YGF@186822|Paenibacillaceae	91061|Bacilli	S	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
CMS3_k127_5962844_6	1121272.KB903250_gene2962	1.231e-19	93.0	2B8BP@1|root,321KE@2|Bacteria,2H5PU@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS3_k127_5962844_3	1297742.A176_06730	9.56e-80	277.0	COG0604@1|root,COG0604@2|Bacteria,1MW2V@1224|Proteobacteria,433WU@68525|delta/epsilon subdivisions,2X2BB@28221|Deltaproteobacteria,2YXH4@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5962844_7	1214101.BN159_8358	3.408e-12	72.0	COG1874@1|root,COG2931@1|root,COG4409@1|root,COG1874@2|Bacteria,COG2931@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	BNR,BNR_2
CMS3_k127_5962844_4	215803.DB30_6281	4.986e-74	263.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YZ03@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,REJ
CMS3_k127_5962844_1	497964.CfE428DRAFT_0631	1.471e-109	386.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_5962844_0	502025.Hoch_4658	6.617e-174	565.0	COG1858@1|root,COG3420@1|root,COG1858@2|Bacteria,COG3420@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_596414_3	1123517.JOMR01000001_gene1183	2.057e-42	160.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,462HB@72273|Thiotrichales	72273|Thiotrichales	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS3_k127_596414_1	1123355.JHYO01000028_gene2693	4.989e-55	203.0	COG0500@1|root,COG0500@2|Bacteria,1QVF3@1224|Proteobacteria,2TYAA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_596414_2	558884.JRGM01000147_gene2361	5.247e-49	180.0	COG1247@1|root,COG1247@2|Bacteria,1QUGY@1224|Proteobacteria,1T1YJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yhhY	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_596414_9	1120950.KB892783_gene316	1.049e-05	58.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	bpr	GO:0005575,GO:0005576	-	ko:K13276,ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Malectin,PKD,Peptidase_M6,Peptidase_S8,SGL
CMS3_k127_596414_5	1335757.SPICUR_06010	5.825e-19	93.0	COG0701@1|root,COG0701@2|Bacteria,1P74D@1224|Proteobacteria	1224|Proteobacteria	S	Predicted permease	MA20_06595	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
CMS3_k127_596414_0	1242864.D187_007480	1.184e-254	813.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS3_k127_596414_4	1192034.CAP_2793	3.68e-22	106.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS3_k127_596414_7	547163.BN979_04843	1.574e-06	60.0	COG3386@1|root,COG3386@2|Bacteria,2GNM1@201174|Actinobacteria,233K1@1762|Mycobacteriaceae	201174|Actinobacteria	G	SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS3_k127_596414_8	1408452.JAGZ01000001_gene3639	2.577e-06	59.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2GNXG@201174|Actinobacteria,23296@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Pkinase
CMS3_k127_596414_6	383372.Rcas_2379	2.176e-08	63.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi,375CP@32061|Chloroflexia	32061|Chloroflexia	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
CMS3_k127_59748_4	211165.AJLN01000116_gene3283	2.135e-33	139.0	COG0457@1|root,COG0457@2|Bacteria,1GJSD@1117|Cyanobacteria,1JJK6@1189|Stigonemataceae	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
CMS3_k127_59748_1	326427.Cagg_3719	3.079e-133	441.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
CMS3_k127_59748_5	861299.J421_5923	3.625e-10	66.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
CMS3_k127_59748_3	479434.Sthe_3254	4.14e-69	262.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_59748_0	926550.CLDAP_15350	1.556e-250	807.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
CMS3_k127_59748_2	1157632.AQWQ01000016_gene3366	3.307e-105	357.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,KR,PP-binding,PS-DH
CMS3_k127_5976857_1	1122182.KB903834_gene6173	1.753e-16	91.0	COG1404@1|root,COG1404@2|Bacteria,2I8MD@201174|Actinobacteria,4DBMJ@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SLH
CMS3_k127_5976857_0	1173027.Mic7113_4717	1.053e-65	228.0	COG1397@1|root,COG1397@2|Bacteria,1G437@1117|Cyanobacteria,1H9KV@1150|Oscillatoriales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
CMS3_k127_5985413_2	555088.DealDRAFT_1161	6.773e-17	87.0	COG4585@1|root,COG4585@2|Bacteria,1V8KW@1239|Firmicutes,24F76@186801|Clostridia	2|Bacteria	T	Integral membrane sensor signal transduction histidine kinase	salK	-	2.7.13.3	ko:K07680,ko:K07778,ko:K11617,ko:K14988	ko02020,ko02024,map02020,map02024	M00476,M00479,M00481,M00522,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3,Response_reg
CMS3_k127_5985413_3	999141.GME_05810	2.356e-16	85.0	COG3153@1|root,COG3153@2|Bacteria,1N4NX@1224|Proteobacteria,1SX5M@1236|Gammaproteobacteria,1XPFC@135619|Oceanospirillales	135619|Oceanospirillales	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_5985413_0	485913.Krac_6031	3.744e-75	256.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_5988667_0	1173028.ANKO01000017_gene220	9.048e-302	943.0	COG0205@1|root,COG0205@2|Bacteria,1G0N7@1117|Cyanobacteria,1H82M@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS3_k127_5988667_1	517418.Ctha_0151	1.298e-198	625.0	COG0205@1|root,COG0205@2|Bacteria,1FDFG@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_5996026_3	316274.Haur_3921	1.874e-29	124.0	COG1295@1|root,COG1295@2|Bacteria,2G7DE@200795|Chloroflexi,377FG@32061|Chloroflexia	32061|Chloroflexia	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS3_k127_5996026_2	326427.Cagg_0604	2.089e-52	211.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GABQ@200795|Chloroflexi,3751C@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HATPase_c,HisKA,PAS_4
CMS3_k127_5996026_4	388413.ALPR1_09770	9.042e-06	55.0	2DP67@1|root,330PV@2|Bacteria,4NWK3@976|Bacteroidetes,47S5B@768503|Cytophagia	976|Bacteroidetes	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
CMS3_k127_5996026_1	1120936.KB907212_gene4978	7.718e-64	234.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4EHDZ@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_5996026_0	1521187.JPIM01000028_gene1594	1.984e-84	285.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_6004914_1	326427.Cagg_2804	1.478e-10	76.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi,376D3@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6004914_0	489825.LYNGBM3L_24300	4.528e-138	481.0	COG1672@1|root,COG2319@1|root,COG4249@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,COG4249@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS3_k127_6004956_3	324602.Caur_1720	6.734e-80	279.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi,376FG@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_6004956_2	926569.ANT_05410	7.907e-103	346.0	COG1609@1|root,COG1609@2|Bacteria,2G7NI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_6004956_5	402880.MmarC5_0839	1.452e-15	89.0	COG0407@1|root,arCOG03323@2157|Archaea,2XV21@28890|Euryarchaeota,23QZS@183939|Methanococci	183939|Methanococci	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS3_k127_6004956_0	1382356.JQMP01000003_gene1949	5.147e-162	524.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi,27XV4@189775|Thermomicrobia	189775|Thermomicrobia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CMS3_k127_6004956_4	572544.Ilyop_1609	2.732e-61	222.0	2EYYJ@1|root,33S5A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6004956_1	945713.IALB_2925	1.447e-136	448.0	COG3004@1|root,COG3004@2|Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS3_k127_6010902_0	42256.RradSPS_0358	2.653e-128	437.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_6010902_1	926550.CLDAP_35990	7.439e-47	174.0	2F1C8@1|root,33UD3@2|Bacteria,2G8D9@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_601374_1	525904.Tter_0927	1.376e-65	240.0	COG2856@1|root,COG4412@1|root,COG2856@2|Bacteria,COG4412@2|Bacteria,2NQMP@2323|unclassified Bacteria	2|Bacteria	E	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_M6,Peptidase_M78
CMS3_k127_601374_2	1304880.JAGB01000002_gene1641	2.269e-18	84.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS3_k127_601374_0	1254432.SCE1572_25980	6.23e-94	314.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria,2YU29@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS3_k127_6014728_4	1043205.AFYF01000083_gene1896	6.939e-09	58.0	COG0584@1|root,COG0584@2|Bacteria,2GIY5@201174|Actinobacteria,4FGUJ@85021|Intrasporangiaceae	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_6014728_1	555088.DealDRAFT_2880	7.07e-66	236.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes	1239|Firmicutes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_6014728_3	572480.Arnit_1327	3.48e-26	122.0	COG3266@1|root,COG3266@2|Bacteria,1RDC1@1224|Proteobacteria,42UDQ@68525|delta/epsilon subdivisions,2YRQK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6014728_2	266117.Rxyl_1129	1.989e-45	179.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,4CPY1@84995|Rubrobacteria	84995|Rubrobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6014728_0	926569.ANT_04320	7.732e-69	243.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_6017751_0	643648.Slip_1027	4.349e-159	518.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,42JPE@68298|Syntrophomonadaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
CMS3_k127_6021218_1	1089545.KB913037_gene2799	5.472e-55	205.0	COG2334@1|root,COG2334@2|Bacteria,2GXZI@201174|Actinobacteria,4E5SH@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_6021218_0	926569.ANT_08740	4.132e-84	283.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_6026805_2	1122611.KB903941_gene2271	1.096e-06	54.0	COG1595@1|root,COG1595@2|Bacteria,2GKGB@201174|Actinobacteria,4EJHK@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6026805_0	1082933.MEA186_29562	1.118e-29	125.0	2DHJZ@1|root,3003A@2|Bacteria,1NIA6@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF5071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5071
CMS3_k127_6026805_1	1227484.C471_16137	1.718e-08	59.0	COG0644@1|root,arCOG00570@2157|Archaea,2XVQQ@28890|Euryarchaeota,23TKS@183963|Halobacteria	183963|Halobacteria	C	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_6027564_1	926550.CLDAP_16610	3.791e-105	356.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2G5VA@200795|Chloroflexi	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	1.5.3.1,2.1.2.10	ko:K00303,ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R00610,R01221,R02300,R04125	RC00022,RC00060,RC00069,RC00183,RC00557,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS3_k127_6027564_6	765420.OSCT_2357	1.26e-16	82.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	mrx1	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
CMS3_k127_6027564_7	1430440.MGMSRv2_3270	1.202e-09	66.0	COG1988@1|root,COG1988@2|Bacteria,1Q0WR@1224|Proteobacteria,2UICE@28211|Alphaproteobacteria,2JXCT@204441|Rhodospirillales	204441|Rhodospirillales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
CMS3_k127_6027564_4	324602.Caur_0726	1.397e-28	122.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS3_k127_6027564_3	1121428.DESHY_60285___1	2.136e-37	151.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,262QN@186807|Peptococcaceae	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS3_k127_6027564_0	926550.CLDAP_23290	2.552e-209	666.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_6027564_5	266117.Rxyl_1241	7.946e-27	126.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_6027564_2	1242864.D187_003824	3.263e-66	229.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,42NBE@68525|delta/epsilon subdivisions,2WMG2@28221|Deltaproteobacteria,2YUJX@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_6031435_7	1235803.C825_00947	1.383e-21	95.0	COG0006@1|root,COG0006@2|Bacteria,4NI1J@976|Bacteroidetes,2FNZP@200643|Bacteroidia,22WTJ@171551|Porphyromonadaceae	976|Bacteroidetes	E	peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
CMS3_k127_6031435_6	243160.BMAA1151	8.273e-54	192.0	COG3631@1|root,COG3631@2|Bacteria,1N05P@1224|Proteobacteria,2W3M0@28216|Betaproteobacteria,1K8JR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_6031435_5	114615.BRADO1514	3.526e-59	210.0	COG0703@1|root,COG0703@2|Bacteria,1NPFH@1224|Proteobacteria,2UMDA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6031435_3	316274.Haur_2467	7.497e-104	349.0	COG1609@1|root,COG1609@2|Bacteria,2G8RS@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_6031435_2	502025.Hoch_3100	1.958e-107	359.0	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,43AJK@68525|delta/epsilon subdivisions,2X5ZT@28221|Deltaproteobacteria,2YUVB@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CMS3_k127_6031435_0	324602.Caur_1075	3.525e-227	721.0	COG1472@1|root,COG1472@2|Bacteria,2G7NE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
CMS3_k127_6031435_1	926550.CLDAP_20760	2.619e-159	523.0	COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,2G7G9@200795|Chloroflexi	200795|Chloroflexi	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
CMS3_k127_6031435_4	926569.ANT_25160	4.781e-92	317.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_6032861_6	1173264.KI913949_gene462	1.904e-08	65.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40,SpoIIE,TIR_2,WD40
CMS3_k127_6032861_7	935840.JAEQ01000001_gene2768	1.295e-06	59.0	COG1708@1|root,COG1708@2|Bacteria,1R03C@1224|Proteobacteria,2TUZ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6032861_0	479435.Kfla_2275	2.164e-123	404.0	2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4DR0C@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6032861_3	1224318.DT73_14505	2.322e-23	111.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RQX7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	sulfurtransferase	ynjE	GO:0003674,GO:0003824,GO:0016740,GO:0016782,GO:0016783	2.8.1.11	ko:K21028	ko04122,map04122	-	R07461	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS3_k127_6032861_4	1280948.HY36_12075	5.508e-21	102.0	COG1073@1|root,COG1073@2|Bacteria,1RC0W@1224|Proteobacteria,2U6C5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FG	alpha, beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,Abhydrolase_6,HIT,Hydrolase_4
CMS3_k127_6032861_5	1198452.Jab_2c09930	1.368e-11	70.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,2WFD1@28216|Betaproteobacteria,478YP@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6032861_1	296591.Bpro_1676	2.717e-85	290.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_6032861_2	639282.DEFDS_1384	8.196e-32	136.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
CMS3_k127_6036558_0	404380.Gbem_2865	4.723e-22	110.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
CMS3_k127_6036558_1	326427.Cagg_0341	6.421e-21	106.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_6036558_2	1173023.KE650771_gene434	2.99e-19	100.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_604499_1	1280954.HPO_10542	3.141e-70	244.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria,43WKC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_2,Kelch_4,Kelch_6
CMS3_k127_604499_0	680198.SCAB_15261	1.041e-98	335.0	COG5274@1|root,COG5274@2|Bacteria,2HH9U@201174|Actinobacteria	201174|Actinobacteria	CI	Indoleamine 2,3-dioxygenase	-	-	1.13.11.52	ko:K00463	ko00380,ko01100,ko05143,map00380,map01100,map05143	M00038	R00678,R02702,R02909,R03628	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	IDO
CMS3_k127_604499_2	179408.Osc7112_6894	1.187e-60	218.0	2F3K3@1|root,33WDF@2|Bacteria,1GDTC@1117|Cyanobacteria	1117|Cyanobacteria	S	AAR2 protein	-	-	-	-	-	-	-	-	-	-	-	-	AAR2
CMS3_k127_604499_3	291112.PAU_00483	3.981e-10	65.0	2A0ZJ@1|root,30P4V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6048495_1	1173025.GEI7407_1785	2.06e-117	403.0	COG1122@1|root,COG2319@1|root,COG1122@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
CMS3_k127_6048495_2	1121904.ARBP01000023_gene4999	1.01e-73	263.0	COG2114@1|root,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia	976|Bacteroidetes	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_12,TPR_8
CMS3_k127_6048495_3	926550.CLDAP_20970	3.424e-60	217.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6048495_0	926569.ANT_10740	1.033e-180	593.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
CMS3_k127_6048706_4	179408.Osc7112_0403	3.699e-42	159.0	2CFUA@1|root,32S2G@2|Bacteria,1G7BR@1117|Cyanobacteria,1HBHX@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6048706_2	1287276.X752_07555	2.524e-81	278.0	COG1082@1|root,COG1082@2|Bacteria,1N1AK@1224|Proteobacteria,2U3TU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_6048706_0	1089551.KE386572_gene2869	5.828e-127	415.0	COG0673@1|root,COG0673@2|Bacteria,1MWNK@1224|Proteobacteria,2U4BM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_6048706_1	526225.Gobs_1239	9.331e-103	350.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4ESSS@85013|Frankiales	201174|Actinobacteria	C	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_6048706_3	1380391.JIAS01000012_gene4124	2.37e-55	205.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,2JXWG@204441|Rhodospirillales	204441|Rhodospirillales	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
CMS3_k127_604937_1	1085623.GNIT_3307	7.81e-35	135.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,46508@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_604937_0	243231.GSU0914	4.247e-142	464.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS3_k127_604939_0	1122222.AXWR01000001_gene1872	5.994e-72	261.0	COG0457@1|root,COG0457@2|Bacteria,1WKXF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_2,TPR_8
CMS3_k127_604939_2	869210.Marky_0228	7.289e-59	222.0	COG0457@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,1WKXF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_2,TPR_8
CMS3_k127_604939_3	1071073.KI530550_gene3608	1.73e-19	95.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HD,His_Phos_1
CMS3_k127_604939_1	391625.PPSIR1_07173	4.636e-60	222.0	COG1881@1|root,COG1881@2|Bacteria	2|Bacteria	S	positive regulation of acetylcholine metabolic process	lppC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06910	-	-	-	-	ko00000	-	-	-	CBM_6,GSDH,PBP,Polyketide_cyc2,YHYH,fn3
CMS3_k127_6050573_0	383372.Rcas_3152	7.097e-12	78.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	3.1.3.5,3.6.1.45	ko:K02027,ko:K10117,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,ko02010,map00230,map00240,map00760,map01100,map01110,map02010	M00196,M00207	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.28	-	-	5_nucleotid_C,GntR,SBP_bac_1,SBP_bac_8
CMS3_k127_6051470_2	373903.Hore_17270	3.676e-90	317.0	COG3379@1|root,COG3379@2|Bacteria,1VHYF@1239|Firmicutes,24VS8@186801|Clostridia	186801|Clostridia	Q	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_6051470_0	926550.CLDAP_17480	3.537e-111	368.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6051470_5	357808.RoseRS_0394	1.59e-13	74.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6051470_4	926550.CLDAP_01940	6.847e-30	138.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
CMS3_k127_6051470_3	485913.Krac_2669	5.54e-79	270.0	COG3959@1|root,COG3959@2|Bacteria,2GA6J@200795|Chloroflexi	200795|Chloroflexi	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS3_k127_6051470_1	485913.Krac_2670	1.97e-105	350.0	COG3958@1|root,COG3958@2|Bacteria	2|Bacteria	G	transketolase activity	fas3	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_6058885_1	696281.Desru_1400	3.198e-34	143.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.5.1.106	ko:K15357	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_3,Abhydrolase_6,Hydrolase_4
CMS3_k127_6058885_2	561229.Dd1591_4022	5.451e-21	100.0	COG0494@1|root,COG0494@2|Bacteria,1QU7P@1224|Proteobacteria,1S7BC@1236|Gammaproteobacteria,2JDR3@204037|Dickeya	1236|Gammaproteobacteria	L	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_6058885_0	926550.CLDAP_29610	1.56e-219	689.0	COG1904@1|root,COG1904@2|Bacteria,2G7Q1@200795|Chloroflexi	200795|Chloroflexi	G	Glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
CMS3_k127_6061085_1	926569.ANT_03270	6.302e-50	183.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi	200795|Chloroflexi	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
CMS3_k127_6061085_0	1382356.JQMP01000003_gene2438	1.937e-204	652.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,27XQ6@189775|Thermomicrobia	189775|Thermomicrobia	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_6080906_1	448385.sce5623	2.589e-65	227.0	COG0500@1|root,COG2226@2|Bacteria,1R7R7@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_6080906_0	309807.SRU_1709	5.047e-130	425.0	COG0252@1|root,COG0252@2|Bacteria,4NE2Z@976|Bacteroidetes,1FJTE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EJ	Asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS3_k127_6087033_1	926569.ANT_23450	1.495e-117	391.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS3_k127_6087033_0	926569.ANT_23460	5.969e-147	475.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS3_k127_6087033_2	1229172.JQFA01000002_gene4156	1.285e-36	151.0	COG1943@1|root,COG1943@2|Bacteria,1G6DG@1117|Cyanobacteria,1HBDG@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_6093265_1	926569.ANT_28010	3.33e-125	409.0	COG1488@1|root,COG1488@2|Bacteria,2G73F@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS3_k127_6093265_0	765420.OSCT_3014	1.877e-200	643.0	COG0326@1|root,COG0326@2|Bacteria,2G60B@200795|Chloroflexi,3751H@32061|Chloroflexia	32061|Chloroflexia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HSP90
CMS3_k127_6093424_0	234267.Acid_7336	1.26e-115	390.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_6098425_2	118005.AWNK01000011_gene136	4.114e-08	58.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
CMS3_k127_6098425_1	998674.ATTE01000001_gene3828	4.203e-48	185.0	COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,1S5V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIGRFAM TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
CMS3_k127_6098425_0	1381123.AYOD01000013_gene2195	3.016e-147	484.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,43I4Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS3_k127_6113056_1	502025.Hoch_1343	4.997e-80	297.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YU5N@29|Myxococcales	28221|Deltaproteobacteria	T	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS3_k127_6113056_2	1349767.GJA_2180	2.106e-32	147.0	COG4995@1|root,COG4995@2|Bacteria,1PGV4@1224|Proteobacteria,2WCRK@28216|Betaproteobacteria,4783V@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
CMS3_k127_6113056_0	1479237.JMLY01000001_gene656	2.974e-82	277.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,466DD@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2818 3-methyladenine DNA glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS3_k127_6115619_0	926569.ANT_10870	6.237e-233	747.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS3_k127_6115619_1	1238190.AMQY01000023_gene352	8.828e-09	63.0	COG1278@1|root,COG1278@2|Bacteria,1N0MM@1224|Proteobacteria,1S8XG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1278 Cold shock proteins	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_6115619_2	1347369.CCAD010000065_gene3669	5.488e-07	59.0	COG1388@1|root,COG2911@1|root,COG1388@2|Bacteria,COG2911@2|Bacteria,1UPFG@1239|Firmicutes	1239|Firmicutes	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_6115619_3	907348.TresaDRAFT_1716	1.197e-05	57.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2J6RF@203691|Spirochaetes	203691|Spirochaetes	M	LysM domain M23 M37 peptidase domain protein	nlpD	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
CMS3_k127_6123230_0	926550.CLDAP_00020	1.861e-153	491.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS3_k127_6123230_1	926550.CLDAP_31710	1.926e-83	301.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS3_k127_6123230_4	1380370.JIBA01000003_gene2738	1.985e-42	175.0	2DQWK@1|root,3393J@2|Bacteria,2IEMK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6123230_2	1458357.BG58_37035	1.922e-45	173.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_6123230_3	926550.CLDAP_14690	1.067e-44	178.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
CMS3_k127_6123230_5	1128421.JAGA01000002_gene1167	1.832e-14	76.0	COG0801@1|root,COG0801@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0041	FolB,HPPK
CMS3_k127_6130389_0	1297742.A176_03619	1.123e-114	383.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS3_k127_6130389_1	649638.Trad_1483	3.543e-81	280.0	COG0647@1|root,COG0647@2|Bacteria,1WMXZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_6130389_2	926569.ANT_13130	2.001e-80	274.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6130389_3	756272.Plabr_1539	3.861e-05	55.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_6131853_16	926569.ANT_08310	2.462e-10	61.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS3_k127_6131853_2	926569.ANT_08320	1.596e-164	527.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS3_k127_6131853_10	383372.Rcas_1320	1.014e-51	189.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi,375IT@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS3_k127_6131853_4	926569.ANT_08340	5.326e-138	451.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_6131853_0	926569.ANT_08350	3.266e-267	847.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_6131853_6	398767.Glov_3131	4.579e-82	285.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS3_k127_6131853_8	926569.ANT_08370	1.255e-74	254.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS3_k127_6131853_14	324602.Caur_2905	1.458e-30	126.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi,375QH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS3_k127_6131853_12	443144.GM21_4000	7.608e-33	130.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS3_k127_6131853_13	443144.GM21_4000	7.608e-33	130.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS3_k127_6131853_15	324602.Caur_2905	1.458e-30	126.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi,375QH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS3_k127_6131853_9	926569.ANT_08370	1.255e-74	254.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS3_k127_6131853_7	398767.Glov_3131	4.579e-82	285.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS3_k127_6131853_1	926569.ANT_08350	3.266e-267	847.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_6131853_5	926569.ANT_08340	5.326e-138	451.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_6131853_11	383372.Rcas_1320	1.014e-51	189.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi,375IT@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS3_k127_6131853_3	926569.ANT_08320	1.596e-164	527.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS3_k127_6131853_17	926569.ANT_08310	2.462e-10	61.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS3_k127_6132391_0	316274.Haur_2169	0.0	1583.0	COG0028@1|root,COG2911@1|root,COG2931@1|root,COG3055@1|root,COG3266@1|root,COG3386@1|root,COG3409@1|root,COG0028@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3266@2|Bacteria,COG3386@2|Bacteria,COG3409@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
CMS3_k127_6132391_3	1120948.KB903244_gene3147	4.828e-16	96.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	He_PIG,Peptidase_S8,SLH,fn3
CMS3_k127_6132391_2	926569.ANT_08030	2.655e-33	153.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_6132391_1	926569.ANT_29790	3.303e-45	171.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS3_k127_6133077_1	1030157.AFMP01000065_gene1151	1.437e-75	265.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2K0QN@204457|Sphingomonadales	204457|Sphingomonadales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS3_k127_6133077_0	1232410.KI421426_gene1487	8.272e-164	529.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43T0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS3_k127_6133077_2	398580.Dshi_2914	2.848e-26	111.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,2U0MD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS3_k127_6138298_4	1463921.JODF01000023_gene673	3.298e-22	100.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_6138298_3	1121918.ARWE01000001_gene366	2.597e-37	156.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock protein DnaJ domain protein	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS3_k127_6138298_0	323098.Nwi_0283	0.0	1569.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3JUU3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_6138298_5	1341151.ASZU01000004_gene336	6.931e-19	94.0	COG0454@1|root,COG0456@2|Bacteria,1VFP8@1239|Firmicutes,4HPVK@91061|Bacilli,27CB8@186824|Thermoactinomycetaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_6138298_1	697282.Mettu_0128	1.893e-56	203.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria,1S6QY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS3_k127_6138298_2	1122947.FR7_0856	9.268e-42	159.0	COG3707@1|root,COG3707@2|Bacteria,1U6TA@1239|Firmicutes,4H1ZW@909932|Negativicutes	909932|Negativicutes	T	Response regulator receiver domain protein	pdtaR	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
CMS3_k127_6140050_3	1128421.JAGA01000002_gene830	9.334e-27	120.0	COG4166@1|root,COG4166@2|Bacteria,2NQQP@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_6140050_1	316274.Haur_2528	6.979e-49	188.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	1.3.1.84,4.2.1.116,6.2.1.36	ko:K14469	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R00919,R03045,R09286	RC00004,RC00014,RC00095,RC00834	ko00000,ko00001,ko00002,ko01000	-	-	-	ACAS_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,AMP-binding_C,ECH_1
CMS3_k127_6140050_2	316274.Haur_2527	6.966e-32	128.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
CMS3_k127_6140050_0	326427.Cagg_2385	1.783e-50	202.0	COG4166@1|root,COG4166@2|Bacteria,2G8A0@200795|Chloroflexi,375R9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_6140050_4	272123.Anacy_2728	6.155e-26	119.0	COG1266@1|root,COG1266@2|Bacteria,1GNMN@1117|Cyanobacteria,1HRG2@1161|Nostocales	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_6140050_6	1123277.KB893220_gene6157	5.184e-08	66.0	COG1361@1|root,COG1520@1|root,COG2133@1|root,COG4932@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2133@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,SdrD_B,SprB
CMS3_k127_6140050_5	926569.ANT_15080	1.794e-24	119.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
CMS3_k127_6142986_4	936572.HMPREF1148_0316	5.639e-15	81.0	COG0477@1|root,COG2814@2|Bacteria,1UJ0G@1239|Firmicutes,4H2N5@909932|Negativicutes	909932|Negativicutes	EGP	Transporter major facilitator family protein	fsr	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_6142986_2	387092.NIS_0278	7.886e-30	122.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,43B6G@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_6142986_3	102129.Lepto7375DRAFT_1307	4.849e-29	121.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	mxaD	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
CMS3_k127_6142986_1	926550.CLDAP_23750	9.307e-165	530.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
CMS3_k127_6142986_0	926550.CLDAP_33880	3.057e-194	617.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS3_k127_615158_2	1499680.CCFE01000021_gene2287	2.515e-07	59.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,4HF1T@91061|Bacilli,1ZFJ2@1386|Bacillus	91061|Bacilli	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_3,VWA_CoxE
CMS3_k127_615158_0	1382306.JNIM01000001_gene2755	7.645e-79	274.0	COG1335@1|root,COG1335@2|Bacteria,2G8KH@200795|Chloroflexi	200795|Chloroflexi	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_615158_1	317619.ANKN01000206_gene2648	1.028e-36	158.0	COG4248@1|root,COG4248@2|Bacteria,1FZV2@1117|Cyanobacteria	1117|Cyanobacteria	S	protein with protein kinase and helix-hairpin-helix DNA-binding domains	-	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	-
CMS3_k127_616683_1	926550.CLDAP_18940	5.772e-58	214.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS3_k127_616683_2	926569.ANT_28940	2.132e-39	160.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CMS3_k127_616683_3	518766.Rmar_0198	3.375e-26	114.0	29ATW@1|root,2ZXTA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_616683_0	177437.HRM2_08620	2.786e-164	527.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2MMM3@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Glucose-1-phosphate adenylyltransferase	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_616683_4	861299.J421_2552	3.823e-22	100.0	COG0546@1|root,COG0546@2|Bacteria,1ZTK9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS3_k127_6167736_3	706587.Desti_0302	1.396e-06	60.0	COG0745@1|root,COG0745@2|Bacteria	706587.Desti_0302|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6167736_1	1158345.JNLL01000001_gene1297	4.755e-14	80.0	COG3431@1|root,COG3431@2|Bacteria,2G446@200783|Aquificae	200783|Aquificae	S	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	Protoglobin,PsiE
CMS3_k127_6167736_2	1089550.ATTH01000001_gene1666	3.43e-07	53.0	COG4753@1|root,COG4753@2|Bacteria,4NP4Q@976|Bacteroidetes	976|Bacteroidetes	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6167736_0	1192034.CAP_0825	1.358e-235	749.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6178483_3	338966.Ppro_2908	3.05e-98	347.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS3_k127_6178483_0	1499967.BAYZ01000052_gene4665	3.73e-149	518.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_6178483_2	709986.Deima_1929	3.451e-114	380.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	ko:K15468	-	-	-	-	ko00000,ko01008	-	-	-	p450
CMS3_k127_6178483_5	751944.HALDL1_11380	3.338e-44	168.0	COG1225@1|root,arCOG00310@2157|Archaea,2XUM4@28890|Euryarchaeota,23UT5@183963|Halobacteria	183963|Halobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	hyrA2	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_6178483_1	1510531.JQJJ01000010_gene2360	7.254e-141	469.0	COG1651@1|root,COG3004@1|root,COG1651@2|Bacteria,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,3JX2W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
CMS3_k127_6178483_4	926569.ANT_12210	1.607e-60	224.0	COG1653@1|root,COG1653@2|Bacteria,2G7EJ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS3_k127_6180600_1	926550.CLDAP_11940	1.115e-28	132.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6180600_0	765913.ThidrDRAFT_4323	1.843e-33	141.0	COG2230@1|root,COG4976@1|root,COG2230@2|Bacteria,COG4976@2|Bacteria,1QZMW@1224|Proteobacteria	1224|Proteobacteria	M	Methionine biosynthesis protein MetW	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Methyltransf_23
CMS3_k127_618519_2	1961.JOAK01000023_gene3781	1.005e-25	113.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_618519_0	485913.Krac_2547	4.016e-106	357.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	2|Bacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2
CMS3_k127_618519_1	935948.KE386494_gene461	3.144e-95	327.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,42FU6@68295|Thermoanaerobacterales	186801|Clostridia	F	Amidohydrolase family	hydA	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1,Urease_alpha
CMS3_k127_6185558_0	1303518.CCALI_01986	2.146e-94	330.0	COG3605@1|root,COG3920@1|root,COG3605@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17,4.2.1.75,4.6.1.1	ko:K00936,ko:K01719,ko:K01768,ko:K02030,ko:K02584,ko:K10441,ko:K13924,ko:K20962	ko00230,ko00860,ko01100,ko01110,ko01120,ko02010,ko02020,ko02025,ko02030,ko04113,ko04213,ko05111,map00230,map00860,map01100,map01110,map01120,map02010,map02020,map02025,map02030,map04113,map04213,map05111	M00121,M00212,M00236,M00506,M00695,M00839	R00089,R00434,R03165	RC00295,RC01861	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035,ko03000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.3	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12,TPR_8
CMS3_k127_618593_0	523841.HFX_2297	1.695e-159	516.0	COG0277@1|root,arCOG00340@2157|Archaea,2Y85H@28890|Euryarchaeota,24157@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
CMS3_k127_618593_2	926550.CLDAP_09590	4.351e-54	207.0	COG1262@1|root,COG4995@1|root,COG1262@2|Bacteria,COG4995@2|Bacteria,2G903@200795|Chloroflexi	200795|Chloroflexi	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
CMS3_k127_618593_3	926550.CLDAP_09580	1.463e-45	180.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi	200795|Chloroflexi	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
CMS3_k127_618593_1	269797.Mbar_A2862	1.175e-106	394.0	COG2319@1|root,arCOG02561@2157|Archaea,2Y41K@28890|Euryarchaeota,2NAYQ@224756|Methanomicrobia	224756|Methanomicrobia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS3_k127_618593_4	1499967.BAYZ01000118_gene3266	4.522e-22	98.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_6192217_0	518766.Rmar_2667	2.371e-186	600.0	COG0475@1|root,COG0569@1|root,COG1762@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,4NFPE@976|Bacteroidetes	976|Bacteroidetes	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_6192217_2	926569.ANT_11320	5.688e-96	326.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6192217_3	1192034.CAP_3530	2.585e-64	229.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
CMS3_k127_6192217_1	1303518.CCALI_01587	4.567e-174	559.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
CMS3_k127_6203187_1	314285.KT71_18441	1.477e-67	235.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,1SANT@1236|Gammaproteobacteria,1J8PD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_6203187_0	864051.BurJ1DRAFT_2685	4.315e-111	371.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS3_k127_6209172_0	935261.JAGL01000011_gene2058	1.295e-45	165.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,43INN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS3_k127_6209172_3	1297863.APJF01000021_gene23	1.33e-27	113.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2U0S6@28211|Alphaproteobacteria,3JYCC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	MA20_23360	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS3_k127_6209172_1	999549.KI421514_gene46	3.048e-41	158.0	COG3805@1|root,COG3805@2|Bacteria,1RIFS@1224|Proteobacteria,2VG1N@28211|Alphaproteobacteria,281Q9@191028|Leisingera	28211|Alphaproteobacteria	Q	Dopa 4,5-dioxygenase family	-	-	-	ko:K10253	-	-	-	-	ko00000,ko01000	-	-	-	DOPA_dioxygen
CMS3_k127_6209172_2	314232.SKA53_08521	2.233e-30	126.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,2TTA9@28211|Alphaproteobacteria,2P8DR@245186|Loktanella	28211|Alphaproteobacteria	O	ATPase with chaperone activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6210251_0	926569.ANT_05660	5.881e-142	466.0	COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi	200795|Chloroflexi	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
CMS3_k127_6211930_0	1499967.BAYZ01000022_gene228	2.521e-185	598.0	COG1743@1|root,COG1743@2|Bacteria	1499967.BAYZ01000022_gene228|-	L	DNA methylAse	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6213894_3	439235.Dalk_4314	1.09e-09	70.0	COG4552@1|root,COG4552@2|Bacteria,1NJ0B@1224|Proteobacteria,42XQI@68525|delta/epsilon subdivisions,2WTCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS3_k127_6213894_1	1265502.KB905942_gene2833	4.957e-50	190.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2VV87@28216|Betaproteobacteria,4AFMD@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2
CMS3_k127_6213894_0	671143.DAMO_0255	1.744e-60	224.0	COG0438@1|root,COG3754@1|root,COG4372@1|root,COG5610@1|root,COG0438@2|Bacteria,COG3754@2|Bacteria,COG4372@2|Bacteria,COG5610@2|Bacteria,2NR6D@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	sll1424	-	2.1.1.80,3.1.1.61	ko:K01991,ko:K02557,ko:K07161,ko:K07484,ko:K13924,ko:K20444,ko:K21471	ko02020,ko02026,ko02030,ko02040,map02020,map02026,map02030,map02040	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01005,ko01011,ko02000,ko02022,ko02035	1.A.30.1,1.B.18,4.D.1.3	GT2,GT4	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,zf-IS66
CMS3_k127_6213894_2	1128421.JAGA01000003_gene3091	3.687e-14	80.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_6221759_0	485913.Krac_6469	2.051e-90	308.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
CMS3_k127_6221759_1	945713.IALB_1599	6.78e-18	98.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
CMS3_k127_6221759_2	383372.Rcas_2811	9.39e-15	88.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	2.7.11.1,3.2.1.50	ko:K01205,ko:K07004,ko:K12132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko04147	-	-	-	DUF3662,DUF916,FHA,NAGLU,NAGLU_C,NAGLU_N,Yop-YscD_cpl
CMS3_k127_6222914_0	485913.Krac_2926	2.236e-118	407.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
CMS3_k127_6222914_1	944479.JQLX01000012_gene1042	8.295e-47	176.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2WJU0@28221|Deltaproteobacteria,2M6A1@213113|Desulfurellales	28221|Deltaproteobacteria	P	Bacterial Na+/H+ antiporter B (NhaB)	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS3_k127_6223517_0	670487.Ocepr_1328	2.768e-162	523.0	COG0441@1|root,COG0441@2|Bacteria,1WI8Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS3_k127_6223517_2	649638.Trad_1292	5.798e-09	68.0	COG0747@1|root,COG0747@2|Bacteria,1WIYQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_6223517_1	996637.SGM_0120	1.307e-16	92.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
CMS3_k127_6229403_0	498761.HM1_2282	7.478e-73	254.0	COG0170@1|root,COG1836@1|root,COG0170@2|Bacteria,COG1836@2|Bacteria,1V7I1@1239|Firmicutes,24GQ3@186801|Clostridia	186801|Clostridia	I	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
CMS3_k127_6229403_1	1382306.JNIM01000001_gene3759	1.067e-31	128.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS3_k127_6243058_4	1410665.JNKR01000009_gene1311	4.394e-54	199.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes	909932|Negativicutes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS3_k127_6243058_6	1121116.KB894779_gene583	4.762e-35	138.0	COG0537@1|root,COG0537@2|Bacteria,1N422@1224|Proteobacteria,2VT5W@28216|Betaproteobacteria,4ADM7@80864|Comamonadaceae	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_6243058_5	1499967.BAYZ01000028_gene1234	9.314e-43	174.0	COG0840@1|root,COG2203@1|root,COG0840@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	pyp	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,HATPase_c,HisKA,MCPsignal,PAS,PAS_3,dCache_1
CMS3_k127_6243058_7	1229780.BN381_230014	1.106e-30	135.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CMS3_k127_6243058_1	649638.Trad_0272	3.967e-113	379.0	COG2309@1|root,COG2309@2|Bacteria,1WI5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_6243058_2	1028800.RG540_CH30740	4.337e-81	277.0	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,2U2W2@28211|Alphaproteobacteria,4BAGJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS3_k127_6243058_9	1550073.JROH01000012_gene2522	9.066e-14	75.0	2AAS0@1|root,3104G@2|Bacteria,1PN4I@1224|Proteobacteria,2V0R0@28211|Alphaproteobacteria,2KAP8@204457|Sphingomonadales	204457|Sphingomonadales	S	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS3_k127_6243058_3	518766.Rmar_0366	7.388e-68	243.0	COG1418@1|root,COG1418@2|Bacteria,4NEZY@976|Bacteroidetes,1FK50@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_6243058_8	123899.JPQP01000018_gene75	1.229e-15	84.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,3T3TE@506|Alcaligenaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
CMS3_k127_6243058_0	485913.Krac_3682	2.707e-154	498.0	COG0673@1|root,COG0673@2|Bacteria,2G7RI@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_6246335_0	926550.CLDAP_01780	3.082e-115	384.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_6246335_1	926550.CLDAP_01790	6.416e-58	213.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS3_k127_6248152_3	1128421.JAGA01000003_gene3464	0.0002948	47.0	COG4586@1|root,COG4586@2|Bacteria	2|Bacteria	S	(ABC) transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6248152_0	926554.KI912620_gene1119	5.501e-102	339.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_6248152_1	926554.KI912620_gene1120	1.015e-84	289.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_6248152_2	1089550.ATTH01000001_gene2270	5.43e-06	59.0	COG0823@1|root,COG0823@2|Bacteria,4PFAG@976|Bacteroidetes,1FKD6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_6249069_0	311424.DhcVS_510	3.63e-61	229.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_6249069_1	324602.Caur_3426	2.171e-41	159.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.39,2.5.1.42,2.5.1.74	ko:K02548,ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00116,M00117	R04520,R05000,R05615,R05617,R06858,R10757	RC00209,RC01171,RC02895,RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Flavodoxin_2,UbiA
CMS3_k127_6255334_7	926550.CLDAP_14290	1.713e-70	246.0	COG4177@1|root,COG4177@2|Bacteria,2G6HP@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_6255334_5	926550.CLDAP_14300	4.049e-105	350.0	COG0559@1|root,COG0559@2|Bacteria,2G6M5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_6255334_0	926550.CLDAP_14310	1.597e-307	953.0	COG1022@1|root,COG1022@2|Bacteria,2G5S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_6255334_4	926550.CLDAP_14320	2.771e-123	405.0	COG0411@1|root,COG0411@2|Bacteria,2G5VI@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_6255334_1	502025.Hoch_3571	8.99e-231	736.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2YY4X@29|Myxococcales	28221|Deltaproteobacteria	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
CMS3_k127_6255334_6	926550.CLDAP_14520	2.741e-91	310.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95,1.17.1.9	ko:K00058,ko:K00122	ko00260,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00519,R01513	RC00031,RC02796	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_6255334_3	1122609.AUGT01000019_gene349	5.371e-156	516.0	COG4719@1|root,COG4733@1|root,COG4719@2|Bacteria,COG4733@2|Bacteria,2I7N6@201174|Actinobacteria	201174|Actinobacteria	S	Fungalysin metallopeptidase (M36)	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF11,FTP,Peptidase_M36
CMS3_k127_6255334_2	926550.CLDAP_24920	9.291e-157	501.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_6255334_8	867845.KI911784_gene1172	8.795e-27	112.0	COG1523@1|root,COG1523@2|Bacteria,2G7WM@200795|Chloroflexi,376JG@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_48,DUF3372
CMS3_k127_6264471_4	1304284.L21TH_1121	1.263e-185	592.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,249WU@186801|Clostridia,36M6Q@31979|Clostridiaceae	186801|Clostridia	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
CMS3_k127_6264471_16	1122963.AUHB01000009_gene1775	1.107e-90	310.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TUPD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator (LacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
CMS3_k127_6264471_3	1121017.AUFG01000028_gene565	3.919e-229	726.0	COG0366@1|root,COG0366@2|Bacteria,2GKT9@201174|Actinobacteria,4FEVJ@85021|Intrasporangiaceae	201174|Actinobacteria	G	Alpha amylase, catalytic domain	ams	-	2.4.1.4	ko:K05341	ko00500,map00500	-	R01823	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
CMS3_k127_6264471_27	765420.OSCT_1178	3.269e-18	100.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,376E7@32061|Chloroflexia	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6264471_28	926550.CLDAP_11920	2.978e-17	97.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,PTPS_related
CMS3_k127_6264471_12	1366050.N234_06120	5.208e-112	374.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VHE6@28216|Betaproteobacteria,1JZVY@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	lysN	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
CMS3_k127_6264471_25	1121422.AUMW01000010_gene1147	3.934e-32	134.0	COG1014@1|root,COG1014@2|Bacteria,1VV4V@1239|Firmicutes,25039@186801|Clostridia	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR
CMS3_k127_6264471_9	1365176.N186_05425	1.792e-124	423.0	COG4231@1|root,arCOG01609@2157|Archaea,2XPN3@28889|Crenarchaeota	28889|Crenarchaeota	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
CMS3_k127_6264471_8	1304885.AUEY01000104_gene2548	9.997e-128	415.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS3_k127_6264471_15	485913.Krac_2435	4.98e-91	310.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_6264471_1	1382306.JNIM01000001_gene1023	4.436e-293	921.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_6264471_19	1382306.JNIM01000001_gene1022	4.467e-66	229.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_6264471_11	398767.Glov_2401	7.127e-115	382.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_6264471_10	398767.Glov_2400	4.763e-115	385.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,430HE@68525|delta/epsilon subdivisions,2WVZI@28221|Deltaproteobacteria,43V4N@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_6264471_14	398767.Glov_2399	1.651e-92	312.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,43V8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS3_k127_6264471_18	398767.Glov_2398	4.501e-67	239.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42R04@68525|delta/epsilon subdivisions,2WMZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM ATPase, BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS3_k127_6264471_30	706587.Desti_2312	7.103e-06	54.0	2EK17@1|root,33DRQ@2|Bacteria,1NNYN@1224|Proteobacteria,42WT5@68525|delta/epsilon subdivisions,2WSVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6264471_20	1397699.JNIS01000001_gene1960	2.063e-63	228.0	COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,4HCP9@91061|Bacilli	91061|Bacilli	K	Phenylacetic acid degradation operon negative regulatory protein PaaX	paaX	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
CMS3_k127_6264471_7	1379698.RBG1_1C00001G0907	6.252e-139	449.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	bamA	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788	3.7.1.21	ko:K07539,ko:K18570	ko00332,ko00362,ko01100,ko01120,ko01130,ko01220,map00332,map00362,map01100,map01120,map01130,map01220	M00541	R05593,R05594,R10696,R10750	RC01430,RC01431,RC03237,RC03270	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_6264471_22	748247.AZKH_2147	1.717e-54	200.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,2VUI3@28216|Betaproteobacteria,2KWVM@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	dch	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_6264471_23	1449080.JQMV01000003_gene1076	1.807e-46	172.0	COG2030@1|root,COG2030@2|Bacteria,1WJC4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_6264471_17	767817.Desgi_1150	5.478e-74	256.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_6264471_6	1231391.AMZF01000039_gene548	5.22e-140	455.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,2W1R6@28216|Betaproteobacteria,3T74Y@506|Alcaligenaceae	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_6264471_5	1379698.RBG1_1C00001G0892	2.96e-140	452.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
CMS3_k127_6264471_24	1380394.JADL01000002_gene1592	1.511e-43	163.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria,2JUEU@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6264471_0	85643.Tmz1t_2959	0.0	1369.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.5.1,3.1.2.25	ko:K18361	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
CMS3_k127_6264471_13	62928.azo1947	1.244e-102	341.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,2KXUS@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	ko:K18362	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	-
CMS3_k127_6264471_21	85643.Tmz1t_2961	1.292e-58	215.0	COG3302@1|root,COG3302@2|Bacteria,1N8SU@1224|Proteobacteria,2WGE7@28216|Betaproteobacteria,2M04N@206389|Rhodocyclales	206389|Rhodocyclales	S	DMSO reductase anchor subunit (DmsC)	-	-	-	ko:K18363	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	DmsC
CMS3_k127_6264471_2	1392838.AWNM01000097_gene131	2.848e-237	753.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,3T1XW@506|Alcaligenaceae	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_6264471_29	1380394.JADL01000004_gene6059	4.834e-08	61.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2TTHE@28211|Alphaproteobacteria,2JQ2E@204441|Rhodospirillales	204441|Rhodospirillales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR
CMS3_k127_6266408_1	926550.CLDAP_05570	1.166e-78	269.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS3_k127_6266408_0	926569.ANT_12010	8.974e-121	398.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_6266408_2	1444309.JAQG01000004_gene3580	1.334e-59	219.0	COG3375@1|root,COG3375@2|Bacteria,1V21D@1239|Firmicutes,4HG3H@91061|Bacilli,272FA@186822|Paenibacillaceae	91061|Bacilli	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_6266408_4	1121448.DGI_2478	1.731e-17	96.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_6266408_3	867845.KI911784_gene338	4.539e-55	198.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi,374VI@32061|Chloroflexia	32061|Chloroflexia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS3_k127_6267140_1	926550.CLDAP_35470	8.9e-62	229.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
CMS3_k127_6267140_0	926550.CLDAP_35490	7.557e-94	321.0	COG2730@1|root,COG3103@1|root,COG2730@2|Bacteria,COG4991@2|Bacteria,2G7Y2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS3_k127_6267140_2	926569.ANT_03880	0.0009174	44.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
CMS3_k127_6267205_1	1051632.TPY_2568	3.915e-77	276.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WD37@538999|Clostridiales incertae sedis	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02003,ko:K02004,ko:K05685,ko:K09810	ko02010,map02010	M00255,M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12,3.A.1.125	-	-	ABC_tran,FtsX
CMS3_k127_6267205_2	1128421.JAGA01000001_gene2242	3.266e-55	199.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	ytrF	-	-	ko:K02004,ko:K16918	ko02010,map02010	M00258,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_6267205_4	391625.PPSIR1_15010	5.948e-18	93.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	yvkB	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Phage_integrase,TetR_C_11,TetR_N
CMS3_k127_6267205_3	216594.MMAR_0597	8.204e-48	177.0	COG5470@1|root,COG5470@2|Bacteria,2GU5A@201174|Actinobacteria,23C12@1762|Mycobacteriaceae	201174|Actinobacteria	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6267205_0	316274.Haur_1999	8.813e-145	488.0	COG0515@1|root,COG2931@1|root,COG3266@1|root,COG3386@1|root,COG0515@2|Bacteria,COG2931@2|Bacteria,COG3266@2|Bacteria,COG3386@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
CMS3_k127_6271199_0	761193.Runsl_5361	1.116e-171	544.0	COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,47JC3@768503|Cytophagia	976|Bacteroidetes	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS3_k127_6271199_1	1499967.BAYZ01000013_gene6455	2.235e-146	479.0	COG0006@1|root,COG0006@2|Bacteria,2NNZX@2323|unclassified Bacteria	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9	ko:K01262,ko:K02027	-	M00207	-	-	ko00000,ko00002,ko01000,ko01002,ko02000	3.A.1.1	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
CMS3_k127_6274880_4	330214.NIDE3489	7.049e-51	188.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS3_k127_6274880_6	272568.GDI1308	6.322e-28	119.0	COG0494@1|root,COG0494@2|Bacteria,1Q4Q3@1224|Proteobacteria,2U7RN@28211|Alphaproteobacteria,2JSJE@204441|Rhodospirillales	204441|Rhodospirillales	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS3_k127_6274880_0	1297742.A176_07099	4.904e-210	664.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NQ9@68525|delta/epsilon subdivisions,2WM2K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
CMS3_k127_6274880_1	483219.LILAB_22120	1.715e-197	630.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria,2Z0QK@29|Myxococcales	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS3_k127_6274880_5	1463917.JODC01000007_gene7491	8.743e-34	133.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS3_k127_6274880_3	1279009.ADICEAN_04083	1.08e-78	273.0	COG0614@1|root,COG0614@2|Bacteria,4NI2Y@976|Bacteroidetes,47M03@768503|Cytophagia	976|Bacteroidetes	P	Periplasmic binding protein	fecB	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
CMS3_k127_6274880_2	1382306.JNIM01000001_gene3067	1.281e-123	424.0	COG1807@1|root,COG1807@2|Bacteria,2G6CP@200795|Chloroflexi	200795|Chloroflexi	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6297901_0	502025.Hoch_3035	1.869e-120	398.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,4300W@68525|delta/epsilon subdivisions,2X35W@28221|Deltaproteobacteria,2YUEH@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_6300569_1	326427.Cagg_3772	4.642e-69	244.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_6300569_0	926569.ANT_16100	7.163e-179	575.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS3_k127_6300569_2	926550.CLDAP_16260	2.914e-39	155.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS3_k127_6300569_4	1211115.ALIQ01000207_gene4746	2.967e-10	71.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,3NBAS@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	FR47-like protein	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_6300569_3	533240.CRC_03180	2.36e-29	119.0	COG2154@1|root,COG2154@2|Bacteria,1G992@1117|Cyanobacteria,1HPMT@1161|Nostocales	1117|Cyanobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS3_k127_6303011_9	85643.Tmz1t_1862	2.699e-06	60.0	COG2318@1|root,COG2318@2|Bacteria,1QVSW@1224|Proteobacteria,2WGTJ@28216|Betaproteobacteria,2KXXP@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_6303011_3	1449346.JQMO01000003_gene2879	4.295e-55	203.0	2DME4@1|root,32QWA@2|Bacteria,2GVI0@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
CMS3_k127_6303011_0	247490.KSU1_B0598	1.996e-140	456.0	COG3497@1|root,COG3497@2|Bacteria,2IXRX@203682|Planctomycetes	203682|Planctomycetes	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
CMS3_k127_6303011_4	1122622.ATWJ01000007_gene1740	6.041e-52	187.0	2DMQT@1|root,32T2H@2|Bacteria,2I823@201174|Actinobacteria	201174|Actinobacteria	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
CMS3_k127_6303011_5	323261.Noc_1872	6.124e-37	151.0	arCOG11412@1|root,31S84@2|Bacteria,1N14M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6303011_8	1157490.EL26_15100	4.063e-13	70.0	arCOG11411@1|root,33A8Q@2|Bacteria,1VM7Z@1239|Firmicutes,4HR18@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6303011_2	1035308.AQYY01000001_gene2741	1.132e-80	274.0	COG1652@1|root,COG1652@2|Bacteria,1V83T@1239|Firmicutes,24KBD@186801|Clostridia	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_6303011_1	323261.Noc_1869	3.265e-88	304.0	COG3500@1|root,COG3500@2|Bacteria,1PX9U@1224|Proteobacteria,1SSDZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Late control gene D protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6303011_6	1173023.KE650771_gene5299	1.154e-28	124.0	COG3501@1|root,COG3501@2|Bacteria,1G3M3@1117|Cyanobacteria	1117|Cyanobacteria	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
CMS3_k127_6303011_7	1123508.JH636458_gene249	1.645e-15	78.0	COG4104@1|root,COG4104@2|Bacteria,2J086@203682|Planctomycetes	203682|Planctomycetes	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
CMS3_k127_6308275_1	316274.Haur_1430	4.435e-91	332.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_6308275_0	926550.CLDAP_20440	1.485e-156	502.0	COG1233@1|root,COG1233@2|Bacteria,2G68M@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amine oxidase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS3_k127_6323079_0	3218.PP1S8_260V6.1	8.415e-247	780.0	COG1506@1|root,KOG2281@2759|Eukaryota,37N3A@33090|Viridiplantae,3GGFF@35493|Streptophyta	35493|Streptophyta	O	dipeptidyl peptidase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_6323079_1	313606.M23134_03794	0.0001951	44.0	COG0500@1|root,COG2226@2|Bacteria,4NJH4@976|Bacteroidetes,47QJV@768503|Cytophagia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_6323905_1	1211814.CAPG01000045_gene2440	2.506e-75	262.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS3_k127_6323905_0	56110.Oscil6304_5272	4.389e-101	334.0	COG4577@1|root,COG4577@2|Bacteria,1G0GA@1117|Cyanobacteria,1H73J@1150|Oscillatoriales	1117|Cyanobacteria	CQ	PFAM BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
CMS3_k127_6323905_3	1499967.BAYZ01000012_gene2485	9.142e-41	153.0	COG4577@1|root,COG4577@2|Bacteria,2NRBW@2323|unclassified Bacteria	2|Bacteria	CQ	COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
CMS3_k127_6323905_5	502025.Hoch_5814	7.349e-26	109.0	COG4576@1|root,COG4576@2|Bacteria,1RIK4@1224|Proteobacteria,4362N@68525|delta/epsilon subdivisions,2X9F2@28221|Deltaproteobacteria,2Z246@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
CMS3_k127_6323905_4	1009370.ALO_06783	9.971e-32	129.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,4H2K4@909932|Negativicutes	909932|Negativicutes	C	Aldehyde dehydrogenase (NAD) family protein	-	-	1.2.1.87	ko:K13922	ko00640,map00640	-	R09097	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_6324337_0	926550.CLDAP_39250	6.391e-62	229.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_6324337_2	1234664.AMRO01000077_gene3451	6.451e-37	144.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HH9B@91061|Bacilli,1WGBI@129337|Geobacillus	91061|Bacilli	C	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
CMS3_k127_6324337_5	926550.CLDAP_01430	7.278e-10	64.0	COG2010@1|root,COG2010@2|Bacteria,2G9TS@200795|Chloroflexi	2|Bacteria	C	Cytochrome c	soxX	-	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cytochrom_C
CMS3_k127_6324337_3	479434.Sthe_2035	3.309e-36	141.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_6324337_7	765420.OSCT_3016	0.0002197	47.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_6324337_4	926550.CLDAP_21830	5.704e-26	118.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6324337_1	926569.ANT_20430	9.216e-58	207.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS3_k127_6324337_6	926550.CLDAP_21810	1.114e-06	55.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS3_k127_6327835_4	1123355.JHYO01000008_gene2603	1.852e-16	86.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6327835_0	760568.Desku_1500	7.142e-70	244.0	COG1152@1|root,COG1152@2|Bacteria,1UKJG@1239|Firmicutes,25FYP@186801|Clostridia,26446@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_10,Fer4_9
CMS3_k127_6327835_3	706587.Desti_4515	6.919e-28	118.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_22,Fer4_8,FrhB_FdhB_C
CMS3_k127_6327835_2	1121468.AUBR01000014_gene2176	6.267e-32	139.0	COG1150@1|root,COG1150@2|Bacteria,1VSKB@1239|Firmicutes,24Z3T@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4_17
CMS3_k127_6327835_1	485915.Dret_0419	9.322e-41	155.0	COG1035@1|root,COG1152@1|root,COG1035@2|Bacteria,COG1152@2|Bacteria,1R4GN@1224|Proteobacteria,42P9J@68525|delta/epsilon subdivisions,2WJ9S@28221|Deltaproteobacteria,2MGKM@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.17.1.9	ko:K00125	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_17,FrhB_FdhB_C
CMS3_k127_6333289_0	935567.JAES01000029_gene2759	1.753e-45	178.0	2ASN4@1|root,31I2V@2|Bacteria,1QFS0@1224|Proteobacteria,1TD1J@1236|Gammaproteobacteria,1X9WY@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6333289_1	370438.PTH_2269	6.663e-34	134.0	COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes,24GZP@186801|Clostridia,262C3@186807|Peptococcaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_6333289_2	269797.Mbar_A3382	0.0006094	51.0	COG2834@1|root,arCOG02470@2157|Archaea,2XWT9@28890|Euryarchaeota,2NB4U@224756|Methanomicrobia	224756|Methanomicrobia	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_6337102_0	765420.OSCT_1222	3.31e-42	164.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_6337102_1	313603.FB2170_13663	2.941e-15	84.0	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,1HXKF@117743|Flavobacteriia,2PH93@252356|Maribacter	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
CMS3_k127_6349245_3	479434.Sthe_3455	6.143e-10	66.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2G5WM@200795|Chloroflexi,27Y7Y@189775|Thermomicrobia	200795|Chloroflexi	DM	Capsular exopolysaccharide family	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,GNVR,Wzz
CMS3_k127_6349245_0	926569.ANT_00970	7.853e-170	545.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS3_k127_6349245_4	888821.HMPREF9394_1026	3.726e-05	57.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V2DN@1239|Firmicutes,4IQ0P@91061|Bacilli	91061|Bacilli	M	Glycosyl hydrolases family 25	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,LysM
CMS3_k127_6349245_1	926550.CLDAP_14670	1.899e-75	277.0	COG3103@1|root,COG4991@2|Bacteria,2G8KJ@200795|Chloroflexi	200795|Chloroflexi	T	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_99
CMS3_k127_6349245_2	562970.Btus_3305	4.263e-10	67.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,27ADN@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS3_k127_6349352_0	1565129.JSFF01000014_gene356	0.0	1094.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,1RPG4@1236|Gammaproteobacteria,2Q8WZ@267890|Shewanellaceae	1236|Gammaproteobacteria	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
CMS3_k127_6349352_2	330214.NIDE0545	5.884e-32	145.0	COG0745@1|root,COG2202@1|root,COG3290@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GGDEF,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE,dCache_1
CMS3_k127_6349352_1	1379281.AVAG01000009_gene642	1.199e-72	276.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2M97J@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_6349352_3	1125863.JAFN01000001_gene2050	3.489e-13	76.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
CMS3_k127_6357951_0	1121382.JQKG01000006_gene3396	9.608e-234	741.0	2DUWA@1|root,33SPG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6357951_1	504728.K649_14465	2.465e-24	107.0	COG2250@1|root,COG2250@2|Bacteria,1WJYR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS3_k127_6357951_2	903818.KI912268_gene2726	4.519e-20	93.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
CMS3_k127_636056_1	1094980.Mpsy_2468	1.577e-87	302.0	arCOG05230@1|root,arCOG05230@2157|Archaea,2Y36Z@28890|Euryarchaeota,2NAJ8@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_636056_0	1120958.AULD01000015_gene1339	2.685e-113	387.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4FKT0@85023|Microbacteriaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_636056_2	926569.ANT_20860	2.514e-57	205.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS3_k127_6363153_1	1094508.Tsac_2526	2.133e-101	344.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,42GR1@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_6363153_5	909613.UO65_1308	3.817e-50	196.0	COG0477@1|root,COG2814@2|Bacteria,2I5F8@201174|Actinobacteria,4E5MI@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_6363153_10	1348663.KCH_35040	2.596e-22	105.0	COG0640@1|root,COG0640@2|Bacteria,2IPJR@201174|Actinobacteria,2M378@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_6363153_8	13035.Dacsa_1054	4.165e-27	127.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	fitD	-	-	ko:K19615	ko02020,map02020	-	-	-	ko00000,ko00001,ko02042	-	-	-	DUF1080,TcdA_TcdB_pore
CMS3_k127_6363153_4	1282362.AEAC466_19965	3.469e-50	185.0	COG0645@1|root,COG0645@2|Bacteria,1RDIX@1224|Proteobacteria,2UPK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS3_k127_6363153_7	649638.Trad_2131	2.138e-44	168.0	COG3981@1|root,COG3981@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) domain	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3
CMS3_k127_6363153_0	357808.RoseRS_1075	9.301e-148	496.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_6363153_2	1120985.AUMI01000004_gene1325	2.994e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6363153_9	234267.Acid_3032	1.008e-23	109.0	COG1309@1|root,COG1309@2|Bacteria,3Y4KN@57723|Acidobacteria	57723|Acidobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6363153_11	1173020.Cha6605_4154	5.386e-22	112.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS3_k127_6363153_3	1120971.AUCA01000025_gene753	3.61e-53	197.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HB38@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_6363153_13	1120936.KB907209_gene1468	5.406e-06	57.0	COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4EG0C@85012|Streptosporangiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_6363153_6	575540.Isop_1601	2.695e-47	183.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,2IY76@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RDD
CMS3_k127_6369503_0	926550.CLDAP_00470	1.088e-95	320.0	COG2897@1|root,COG2897@2|Bacteria,2G6J9@200795|Chloroflexi	200795|Chloroflexi	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS3_k127_6369503_1	1166018.FAES_3473	2.708e-22	111.0	COG2340@1|root,COG2340@2|Bacteria,4NSVB@976|Bacteroidetes,47PIF@768503|Cytophagia	976|Bacteroidetes	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_6369503_2	868131.MSWAN_0053	6.79e-08	65.0	COG3291@1|root,arCOG09475@1|root,arCOG02508@2157|Archaea,arCOG09475@2157|Archaea,2Y37E@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHB_HEX_C_1,PKD
CMS3_k127_6379703_1	1128421.JAGA01000002_gene1598	5.379e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6379703_0	357808.RoseRS_1037	3.153e-08	66.0	COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia	32061|Chloroflexia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6379812_9	666509.RCA23_c18830	2.389e-05	53.0	COG0457@1|root,COG0457@2|Bacteria,1NGEZ@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
CMS3_k127_6379812_3	1896.JOAU01000013_gene1842	5.327e-47	187.0	COG0501@1|root,COG0501@2|Bacteria,2GSB3@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_6379812_0	926560.KE387023_gene1698	8.671e-240	752.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1WM1W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KOT	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Response_reg
CMS3_k127_6379812_2	926560.KE387023_gene2289	2.245e-148	490.0	COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS3_k127_6379812_5	395493.BegalDRAFT_0862	5.442e-33	147.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,1S3T2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CoA-binding protein	yccU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS3_k127_6379812_8	1229276.DI53_3514	3.214e-12	78.0	COG5061@1|root,COG5061@2|Bacteria	2|Bacteria	OU	protein folding in endoplasmic reticulum	satE	-	-	ko:K19134	-	-	-	-	ko00000,ko02048	-	-	-	DUF3307
CMS3_k127_6379812_1	485913.Krac_5655	2.549e-155	501.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6379812_6	235985.BBPN01000014_gene5516	8.476e-24	105.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria,2NJNR@228398|Streptacidiphilus	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_6379812_4	1192034.CAP_0198	1.711e-38	148.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,432ET@68525|delta/epsilon subdivisions,2X94U@28221|Deltaproteobacteria,2Z1Y0@29|Myxococcales	28221|Deltaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_6379812_7	1121022.ABENE_12345	1.725e-22	98.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,2KF4J@204458|Caulobacterales	204458|Caulobacterales	E	TIGRFAM pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
CMS3_k127_639137_3	926569.ANT_25670	1.41e-45	178.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
CMS3_k127_639137_2	1500259.JQLD01000002_gene2884	1.096e-49	184.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TS0V@28211|Alphaproteobacteria,4BDTJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
CMS3_k127_639137_7	1123060.JONP01000023_gene2669	3.032e-12	71.0	COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,2UF7G@28211|Alphaproteobacteria,2JTVD@204441|Rhodospirillales	204441|Rhodospirillales	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS3_k127_639137_0	1122604.JONR01000001_gene2026	6.365e-108	358.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,1RQ2R@1236|Gammaproteobacteria,1X41X@135614|Xanthomonadales	135614|Xanthomonadales	M	3-beta hydroxysteroid dehydrogenase	cdh1	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
CMS3_k127_639137_1	221288.JH992901_gene1753	9.834e-106	353.0	COG0451@1|root,COG0451@2|Bacteria,1G2DP@1117|Cyanobacteria,1JICN@1189|Stigonemataceae	1117|Cyanobacteria	M	Male sterility protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_639137_5	316274.Haur_2897	3.068e-21	99.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS3_k127_639137_6	1356852.N008_17275	1.285e-13	80.0	2E6HY@1|root,33156@2|Bacteria,4NUZX@976|Bacteroidetes,47SVA@768503|Cytophagia	976|Bacteroidetes	S	2-dehydro-3-deoxyphosphooctonate aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_639137_4	390989.JOEG01000001_gene4972	1.235e-38	149.0	COG4243@1|root,COG4243@2|Bacteria,2HG56@201174|Actinobacteria,4DHAS@85008|Micromonosporales	201174|Actinobacteria	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6393984_2	926550.CLDAP_35360	4.04e-40	161.0	COG1994@1|root,COG1994@2|Bacteria,2G8E2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_6393984_1	926569.ANT_09480	7.133e-52	199.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS3_k127_6393984_0	926550.CLDAP_09270	4.408e-70	244.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_6394415_0	926569.ANT_08530	1.663e-119	392.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_6394415_1	1463917.JODC01000001_gene338	1.005e-57	209.0	COG2820@1|root,COG2820@2|Bacteria,2I4KP@201174|Actinobacteria	201174|Actinobacteria	F	Phosphorylase superfamily	udp	-	2.4.2.1,2.4.2.3	ko:K00757,ko:K03784	ko00230,ko00240,ko00760,ko00983,ko01100,ko01110,map00230,map00240,map00760,map00983,map01100,map01110	-	R01561,R01863,R01876,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08229,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_6394415_2	369723.Strop_1198	3.142e-05	56.0	COG0454@1|root,COG0456@2|Bacteria,2I5PN@201174|Actinobacteria,4DMP8@85008|Micromonosporales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
CMS3_k127_6435367_2	871963.Desdi_0959	4.423e-48	190.0	COG2203@1|root,COG4585@1|root,COG5000@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5000@2|Bacteria,1TR88@1239|Firmicutes,250AK@186801|Clostridia,264XI@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PAS_9
CMS3_k127_6435367_0	1382306.JNIM01000001_gene1045	4.521e-63	223.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6435367_1	1121441.AUCX01000002_gene2811	1.251e-52	200.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42N47@68525|delta/epsilon subdivisions,2WIKZ@28221|Deltaproteobacteria,2M8JX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	qrcD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS3_k127_6436916_0	926550.CLDAP_23630	3.002e-52	190.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6436916_3	443218.AS9A_0989	9.054e-08	64.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_6436916_1	765420.OSCT_0497	2.476e-22	106.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,377B3@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
CMS3_k127_6436916_2	926569.ANT_20810	8.479e-19	89.0	COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
CMS3_k127_6445987_2	1157638.KB892157_gene1423	0.0002911	52.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2I8RI@201174|Actinobacteria	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,TPR_7
CMS3_k127_6445987_1	316274.Haur_1112	5.301e-49	193.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	ko:K16247	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,NB-ARC,TPR_12,TPR_7
CMS3_k127_6445987_0	1047013.AQSP01000122_gene2229	1.454e-252	791.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_6448882_0	1382306.JNIM01000001_gene1511	2.355e-265	854.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,TPR_8
CMS3_k127_6448882_1	1298863.AUEP01000008_gene1241	1.151e-56	209.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
CMS3_k127_6448882_3	1382306.JNIM01000001_gene1513	1.77e-27	121.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
CMS3_k127_6448882_2	1231391.AMZF01000022_gene1227	5.786e-48	184.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,3T6KB@506|Alcaligenaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase class IV	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS3_k127_6456220_4	266117.Rxyl_1124	4.083e-15	76.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CPVK@84995|Rubrobacteria	84995|Rubrobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS3_k127_6456220_0	316274.Haur_4831	1.503e-120	398.0	COG2170@1|root,COG2170@2|Bacteria,2G5NR@200795|Chloroflexi,375BI@32061|Chloroflexia	32061|Chloroflexia	F	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
CMS3_k127_6456220_1	485913.Krac_4965	1.044e-68	240.0	COG2197@1|root,COG2197@2|Bacteria,2G8M7@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6456220_2	485913.Krac_7099	3.684e-56	213.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	ydfH	-	2.7.13.3	ko:K07675,ko:K11623	ko02020,map02020	M00473,M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
CMS3_k127_6456220_3	1487921.DP68_06660	7.913e-37	153.0	2ET8I@1|root,3147J@2|Bacteria,1USUA@1239|Firmicutes,24ZT1@186801|Clostridia,36QDI@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6462994_2	1009370.ALO_00305	9.682e-31	126.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4H32Z@909932|Negativicutes	909932|Negativicutes	P	oligopeptide transport system permease protein OppB	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS3_k127_6462994_1	483219.LILAB_33785	9.608e-39	148.0	COG0640@1|root,COG0640@2|Bacteria,1QVFX@1224|Proteobacteria	1224|Proteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
CMS3_k127_6462994_0	1128421.JAGA01000001_gene2038	2.498e-145	496.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,SpoIIE
CMS3_k127_6462994_3	1322246.BN4_11907	1.006e-15	81.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42WXG@68525|delta/epsilon subdivisions,2WT19@28221|Deltaproteobacteria,2MGKC@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS3_k127_6490787_2	926550.CLDAP_01660	1.257e-82	284.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_6490787_1	926550.CLDAP_09010	1.942e-94	317.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_6490787_3	926569.ANT_09850	7.1e-06	58.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6490787_0	1254432.SCE1572_38650	2.843e-107	372.0	COG4886@1|root,COG4886@2|Bacteria,1P5D8@1224|Proteobacteria,433SH@68525|delta/epsilon subdivisions,2WXRP@28221|Deltaproteobacteria,2Z2SK@29|Myxococcales	28221|Deltaproteobacteria	S	DUF3160	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160
CMS3_k127_6493151_5	177437.HRM2_44020	2.584e-13	73.0	2EHW9@1|root,32PEV@2|Bacteria,1P1KH@1224|Proteobacteria,431FX@68525|delta/epsilon subdivisions,2WWEW@28221|Deltaproteobacteria,2MNY1@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6493151_3	316274.Haur_3248	9.624e-49	181.0	2DMXT@1|root,32UAK@2|Bacteria,2G7DN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6493151_4	1454007.JAUG01000024_gene890	5.878e-26	116.0	2E1NE@1|root,32WZB@2|Bacteria,4NU37@976|Bacteroidetes,1ITTK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6493151_1	1265505.ATUG01000001_gene4242	1.046e-65	234.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria,2MNCD@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_6493151_2	448385.sce8469	3.314e-54	211.0	COG0639@1|root,COG0639@2|Bacteria,1QQKD@1224|Proteobacteria,43EN6@68525|delta/epsilon subdivisions,2X9QX@28221|Deltaproteobacteria,2YYXC@29|Myxococcales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_6493151_0	1121033.AUCF01000005_gene5152	9.861e-131	428.0	COG0520@1|root,COG0520@2|Bacteria,1MX5B@1224|Proteobacteria,2TVGK@28211|Alphaproteobacteria,2JQZW@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_6507378_0	369723.Strop_3816	2.616e-13	83.0	COG0739@1|root,COG0739@2|Bacteria,2GU2Q@201174|Actinobacteria,4DCWB@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M23
CMS3_k127_6524819_7	926569.ANT_09570	4.515e-22	108.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS3_k127_6524819_2	357808.RoseRS_3184	7.385e-137	443.0	COG0714@1|root,COG0714@2|Bacteria,2G8BI@200795|Chloroflexi,377XH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_6524819_3	1499967.BAYZ01000089_gene5038	1.302e-116	392.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_6524819_0	373903.Hore_15800	7.574e-161	521.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WB74@53433|Halanaerobiales	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS3_k127_6524819_8	1403313.AXBR01000014_gene2203	0.0001924	46.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6524819_4	7739.XP_002591747.1	8.748e-77	267.0	COG1446@1|root,KOG1592@2759|Eukaryota,38JIS@33154|Opisthokonta,3BB1E@33208|Metazoa,3CRC6@33213|Bilateria,47ZN8@7711|Chordata	33208|Metazoa	E	asparagine catabolic process via L-aspartate	ASRGL1	GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006528,GO:0006530,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008798,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0019439,GO:0019538,GO:0019752,GO:0032787,GO:0033345,GO:0034641,GO:0042737,GO:0043170,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0070011,GO:0071704,GO:0072329,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
CMS3_k127_6524819_1	518766.Rmar_2132	3.955e-148	482.0	COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,1FIYR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase dimerisation domain	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_6524819_6	926569.ANT_11700	2.18e-53	194.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS3_k127_6524819_5	926569.ANT_11710	1.125e-71	249.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_6526846_4	886293.Sinac_6751	7.031e-19	100.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.52	ko:K01186,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	M00079	R00022,R04018,R06004,R11316	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	-	GH20,GH33	-	BNR,BNR_2
CMS3_k127_6526846_3	1283300.ATXB01000001_gene128	3.064e-21	108.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,1S27X@1236|Gammaproteobacteria,1XF6U@135618|Methylococcales	135618|Methylococcales	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6526846_0	469383.Cwoe_4383	3.111e-193	618.0	COG2040@1|root,COG2264@1|root,COG2040@2|Bacteria,COG2264@2|Bacteria,2HQK7@201174|Actinobacteria,4CS5N@84995|Rubrobacteria	84995|Rubrobacteria	EJ	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PrmA,S-methyl_trans
CMS3_k127_6526846_1	709797.CSIRO_0066	9.71e-193	616.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,3JVAX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_6526846_2	1500301.JQMF01000023_gene5580	5.843e-82	277.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TUY3@28211|Alphaproteobacteria,4BCP0@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_6526846_5	883080.HMPREF9697_00005	6.053e-07	55.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TSX8@28211|Alphaproteobacteria,3JTIH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CMS3_k127_6538194_9	1121933.AUHH01000005_gene3418	1.007e-41	159.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria,4DV1F@85009|Propionibacteriales	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
CMS3_k127_6538194_5	926569.ANT_30210	1.441e-86	304.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	salK	-	2.7.13.3	ko:K07680,ko:K07778,ko:K11617,ko:K14988	ko02020,ko02024,map02020,map02024	M00476,M00479,M00481,M00522,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
CMS3_k127_6538194_7	926569.ANT_30220	4.156e-68	239.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	devR	GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02479,ko:K07695	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_6538194_0	926550.CLDAP_31970	0.0	1270.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS3_k127_6538194_8	357808.RoseRS_2423	2.322e-67	237.0	COG0500@1|root,COG2226@2|Bacteria,2G9CY@200795|Chloroflexi,375EP@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_6538194_4	357808.RoseRS_3870	3.839e-102	338.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6538194_2	443143.GM18_4171	1.4e-141	456.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42Q4Y@68525|delta/epsilon subdivisions,2WKZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_6538194_3	357808.RoseRS_3868	1.706e-118	393.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi,375E3@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_6538194_10	316274.Haur_3849	3.519e-38	165.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_6538194_1	324602.Caur_3613	6.833e-211	673.0	COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,2GAJY@200795|Chloroflexi,375YR@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS3_k127_6538194_11	1306174.JODP01000002_gene5474	3.459e-30	125.0	COG0748@1|root,COG0748@2|Bacteria,2IBET@201174|Actinobacteria	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_6538194_12	105420.BBPO01000046_gene992	1.988e-15	81.0	COG0748@1|root,COG0748@2|Bacteria,2IBET@201174|Actinobacteria	201174|Actinobacteria	P	coenzyme F420 binding	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_6538194_13	298654.FraEuI1c_2028	0.0001159	53.0	COG0454@1|root,COG0456@2|Bacteria,2GVT5@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS3_k127_6538194_6	479434.Sthe_0598	1.86e-69	249.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_6557367_3	926569.ANT_31670	3.498e-21	94.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS3_k127_6557367_1	926569.ANT_11910	7.347e-74	256.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_6557367_2	324602.Caur_0190	4.397e-36	149.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS3_k127_6557367_0	349521.HCH_06922	6.718e-77	278.0	COG3291@1|root,COG3591@1|root,COG3291@2|Bacteria,COG3591@2|Bacteria,1QDPR@1224|Proteobacteria,1RN6D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,Trypsin_2
CMS3_k127_6586559_3	33876.JNXY01000009_gene8908	3.652e-66	250.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulator	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	GerE,Guanylate_cyc,NB-ARC
CMS3_k127_6586559_5	926569.ANT_17690	3.931e-22	101.0	COG1357@1|root,COG1357@2|Bacteria,2G7HW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_6586559_9	697284.ERIC2_c11090	4.185e-11	66.0	COG0500@1|root,COG2226@2|Bacteria,1TRW7@1239|Firmicutes,4HJG4@91061|Bacilli,26VYB@186822|Paenibacillaceae	91061|Bacilli	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
CMS3_k127_6586559_7	1123389.ATXJ01000011_gene1023	1.73e-17	96.0	COG1409@1|root,COG1409@2|Bacteria,1WINK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_6586559_4	313612.L8106_07606	8.854e-63	225.0	COG0500@1|root,COG2226@2|Bacteria,1G2V9@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_6586559_1	1415754.JQMK01000002_gene3377	9.286e-202	647.0	COG0745@1|root,COG2909@1|root,COG0745@2|Bacteria,COG2909@2|Bacteria,1N5KV@1224|Proteobacteria,1SMMI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
CMS3_k127_6586559_0	240015.ACP_0020	6.446e-243	771.0	COG1472@1|root,COG1472@2|Bacteria,3Y3M7@57723|Acidobacteria,2JKHP@204432|Acidobacteriia	204432|Acidobacteriia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS3_k127_6586559_2	316274.Haur_4586	7.805e-104	349.0	COG0667@1|root,COG0667@2|Bacteria,2G7TU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_6586559_11	1449976.KALB_6179	2.014e-05	52.0	2A6GY@1|root,30VA5@2|Bacteria,2H9JV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6586559_6	886293.Sinac_2465	1.448e-17	94.0	2EMTG@1|root,33FFU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS3_k127_6586559_10	886293.Sinac_7551	5.31e-11	63.0	COG0491@1|root,COG0491@2|Bacteria,2J4KU@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_6589308_0	204669.Acid345_0576	6.798e-182	574.0	COG2502@1|root,COG2502@2|Bacteria,3Y6DN@57723|Acidobacteria	57723|Acidobacteria	H	Aspartate-ammonia ligase	-	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
CMS3_k127_6604109_3	745310.G432_07310	5.005e-13	71.0	28V8Y@1|root,2ZHBX@2|Bacteria,1RD5G@1224|Proteobacteria,2U0PF@28211|Alphaproteobacteria,2K3HQ@204457|Sphingomonadales	204457|Sphingomonadales	C	Methylamine dehydrogenase, L chain	-	-	1.4.9.1	ko:K15228	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_L
CMS3_k127_6604109_0	1121374.KB891592_gene2906	1.14e-52	193.0	COG0526@1|root,COG0526@2|Bacteria,1R3WA@1224|Proteobacteria,1S5PZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	AhpC/TSA family	mauD	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_6604109_1	318586.Pden_4731	3.461e-25	113.0	COG2259@1|root,COG2259@2|Bacteria,1NAMA@1224|Proteobacteria,2U9W5@28211|Alphaproteobacteria,2PX4I@265|Paracoccus	28211|Alphaproteobacteria	S	Methylamine utilisation protein MauE	mauE	-	-	-	-	-	-	-	-	-	-	-	MauE
CMS3_k127_6604109_2	940282.CADQ01000054_gene584	1.29e-13	73.0	COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,2U2K2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	methylamine dehydrogenase heavy	mauB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.4.9.1	ko:K15229	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_H
CMS3_k127_6606307_2	926569.ANT_03160	1.013e-10	64.0	COG1164@1|root,COG1164@2|Bacteria,2G5SV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS3_k127_6606307_1	1379698.RBG1_1C00001G1318	4.667e-16	91.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_6606307_0	324602.Caur_3475	1.808e-132	433.0	COG0438@1|root,COG0438@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
CMS3_k127_6609502_0	926550.CLDAP_35470	3.626e-61	241.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
CMS3_k127_6611635_4	1499967.BAYZ01000014_gene6384	8.064e-83	279.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_6611635_1	237368.SCABRO_01358	1.599e-124	405.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_6611635_0	326427.Cagg_1542	3.861e-153	489.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS3_k127_6611635_6	926569.ANT_06280	3.358e-32	132.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
CMS3_k127_6611635_2	1337936.IJ00_01720	2.301e-115	394.0	COG1807@1|root,COG1807@2|Bacteria,1G0W2@1117|Cyanobacteria,1HRA1@1161|Nostocales	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6611635_5	316274.Haur_0823	1.912e-79	271.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi,376PV@32061|Chloroflexia	32061|Chloroflexia	F	PFAM phosphoribulokinase uridine kinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS3_k127_6611635_3	1280950.HJO_14772	5.235e-105	352.0	COG2374@1|root,COG2374@2|Bacteria,1R5QF@1224|Proteobacteria,2U002@28211|Alphaproteobacteria,43XPD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_6611635_7	935836.JAEL01000111_gene701	1.331e-10	68.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus	91061|Bacilli	S	COG1073 Hydrolases of the alpha beta superfamily	yqkD	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_6611746_3	357808.RoseRS_2507	3.807e-09	64.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6611746_1	926550.CLDAP_04470	9.668e-13	82.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6611746_2	357808.RoseRS_0394	1.159e-10	75.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_6611746_0	234267.Acid_1421	6.718e-27	128.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_6617235_0	349521.HCH_04864	5.693e-178	573.0	COG2866@1|root,COG4935@1|root,COG2866@2|Bacteria,COG4935@2|Bacteria,1PFUZ@1224|Proteobacteria,1RYRG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_M14
CMS3_k127_6636510_3	1206735.BAGG01000056_gene2285	1.826e-19	93.0	COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4FYDU@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_6636510_1	485913.Krac_6991	5.84e-108	375.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_6636510_2	485913.Krac_6031	2.945e-78	269.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6636510_5	398580.Dshi_0232	0.0002738	53.0	COG2931@1|root,COG2931@2|Bacteria,1NV5Z@1224|Proteobacteria,2URN3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	Hint_2
CMS3_k127_6636510_4	1232429.CBLL010000153_gene718	2.088e-14	75.0	COG3093@1|root,COG3093@2|Bacteria,2IR2S@201174|Actinobacteria,1W9SM@1268|Micrococcaceae	201174|Actinobacteria	K	Helix-turn-helix	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CMS3_k127_6636510_0	1192034.CAP_5407	1.917e-206	653.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_6651570_0	326427.Cagg_3180	1.712e-146	484.0	COG0366@1|root,COG0366@2|Bacteria,2G7J7@200795|Chloroflexi,377YN@32061|Chloroflexia	32061|Chloroflexia	G	Alpha-amylase domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
CMS3_k127_6651570_1	1313421.JHBV01000016_gene5608	9.255e-74	267.0	COG0457@1|root,COG0457@2|Bacteria,4NND8@976|Bacteroidetes	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_6652349_3	1303518.CCALI_02617	2.083e-34	136.0	COG1488@1|root,COG1488@2|Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS3_k127_6652349_6	926550.CLDAP_12350	0.0002579	52.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
CMS3_k127_6652349_1	926569.ANT_19510	5.728e-65	246.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
CMS3_k127_6652349_2	926550.CLDAP_22710	3.78e-40	166.0	COG0457@1|root,COG0457@2|Bacteria	926550.CLDAP_22710|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6652349_0	926550.CLDAP_22690	1.218e-110	377.0	COG1215@1|root,COG2148@1|root,COG1215@2|Bacteria,COG2148@2|Bacteria,2G866@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Glycos_transf_2
CMS3_k127_6652349_5	1045858.Bint_0564	4.705e-18	98.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_6652349_4	1089547.KB913013_gene2235	6.684e-19	100.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
CMS3_k127_666729_0	926569.ANT_11080	9.967e-159	510.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS3_k127_666729_2	926569.ANT_11090	1.109e-77	272.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS3_k127_666729_1	1121380.JNIW01000046_gene1081	5.147e-79	274.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS3_k127_666729_4	357808.RoseRS_3942	3.564e-55	209.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS3_k127_666729_3	661478.OP10G_2200	8.961e-62	229.0	2DQGC@1|root,336PP@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
CMS3_k127_666729_5	1499967.BAYZ01000052_gene4665	2.975e-35	141.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_6670492_1	240016.ABIZ01000001_gene2223	2.265e-103	350.0	COG0624@1|root,COG0624@2|Bacteria,46VZE@74201|Verrucomicrobia,2IW3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_6670492_0	1444712.BN1013_00667	4.263e-113	388.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	aidB	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
CMS3_k127_6670492_2	383372.Rcas_3420	4.487e-56	222.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
CMS3_k127_6670492_5	865861.AZSU01000006_gene1407	2.856e-06	59.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	2|Bacteria	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,YkuD
CMS3_k127_6670492_4	926569.ANT_30860	6.837e-36	146.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_6670492_3	32057.KB217478_gene6752	3.087e-48	186.0	COG2133@1|root,COG2133@2|Bacteria,1G06W@1117|Cyanobacteria,1HJ6F@1161|Nostocales	1117|Cyanobacteria	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_6672943_1	926569.ANT_28000	4.154e-139	465.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_6672943_8	1128421.JAGA01000002_gene830	1.017e-36	159.0	COG4166@1|root,COG4166@2|Bacteria,2NQQP@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_6672943_4	383372.Rcas_3365	1.727e-55	209.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi,375M8@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS3_k127_6672943_6	395493.BegalDRAFT_0733	2.386e-46	190.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
CMS3_k127_6672943_2	926569.ANT_31560	3.294e-75	267.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CMS3_k127_6672943_7	926550.CLDAP_09610	3.361e-37	153.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_6672943_9	926550.CLDAP_09600	9.715e-31	141.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	Collagen
CMS3_k127_6672943_5	655815.ZPR_0969	4.219e-47	178.0	COG0745@1|root,COG0745@2|Bacteria,4NHXA@976|Bacteroidetes,1HZWH@117743|Flavobacteriia	976|Bacteroidetes	KT	transcriptional regulator	cusR	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_6672943_0	321327.CYA_2481	2.023e-150	493.0	COG3119@1|root,COG3119@2|Bacteria,1G35S@1117|Cyanobacteria,1H28E@1129|Synechococcus	1117|Cyanobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS3_k127_6672943_3	1487953.JMKF01000064_gene4752	7.562e-61	221.0	COG0682@1|root,COG0682@2|Bacteria,1G23G@1117|Cyanobacteria	1117|Cyanobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_6677849_2	1121430.JMLG01000023_gene1450	2.777e-56	209.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,261MT@186807|Peptococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K19954	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
CMS3_k127_6677849_1	1207063.P24_00945	4.293e-94	322.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_6677849_0	745014.OMB55_00020420	3.876e-140	457.0	COG0665@1|root,COG0665@2|Bacteria,1R40G@1224|Proteobacteria,1SME5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_6677849_3	1219065.VPR01S_21_00210	7.62e-35	140.0	COG2606@1|root,COG2606@2|Bacteria,1QJRS@1224|Proteobacteria,1SHYA@1236|Gammaproteobacteria,1XXFV@135623|Vibrionales	135623|Vibrionales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS3_k127_6677849_4	445972.ANACOL_01275	1.499e-21	105.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia,3WIE7@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS3_k127_6690686_6	1123258.AQXZ01000011_gene1655	1.069e-38	159.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4G01K@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_6690686_5	1335760.ASTG01000017_gene3465	1.238e-40	163.0	2E40H@1|root,32YXB@2|Bacteria,1NE9K@1224|Proteobacteria,2UH9T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_6690686_0	1123276.KB893260_gene2622	4.598e-72	256.0	28IDY@1|root,2Z8G3@2|Bacteria,4NJQW@976|Bacteroidetes,47MN8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6690686_4	221359.RS9916_38527	3.112e-43	169.0	COG4424@1|root,COG4424@2|Bacteria,1GMXD@1117|Cyanobacteria,1GZVY@1129|Synechococcus	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_6690686_1	227377.CBU_0838	1.279e-65	240.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,1RMDT@1236|Gammaproteobacteria,1JCFG@118969|Legionellales	118969|Legionellales	M	Glycosyltransferase Family 4	capM2_2	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_6690686_3	867845.KI911784_gene2892	1.675e-46	179.0	COG1216@1|root,COG1216@2|Bacteria,2G6TR@200795|Chloroflexi,3769F@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS3_k127_6690686_2	521011.Mpal_0619	6.495e-53	198.0	COG0463@1|root,arCOG01381@2157|Archaea,2XVM0@28890|Euryarchaeota,2NADC@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6690686_7	436308.Nmar_1096	1.162e-37	154.0	arCOG09395@1|root,arCOG09395@2157|Archaea,41T04@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS3_k127_6690686_8	1521187.JPIM01000097_gene2706	1.73e-37	153.0	COG1216@1|root,COG1216@2|Bacteria,2G97Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6690686_9	926569.ANT_29410	8.302e-37	140.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_669239_1	479434.Sthe_0598	1.167e-76	282.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_669239_4	381666.H16_A0105	1.417e-35	140.0	COG2050@1|root,COG2050@2|Bacteria,1RGXI@1224|Proteobacteria,2VW0R@28216|Betaproteobacteria,1KBQ3@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_669239_3	316274.Haur_0342	2.274e-46	177.0	COG1428@1|root,COG1428@2|Bacteria,2G8Z7@200795|Chloroflexi	200795|Chloroflexi	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
CMS3_k127_669239_6	886293.Sinac_2108	2.073e-14	79.0	COG5485@1|root,COG5485@2|Bacteria,2J0V1@203682|Planctomycetes	203682|Planctomycetes	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS3_k127_669239_2	1464048.JNZS01000009_gene5674	9.83e-63	228.0	COG3178@1|root,COG3178@2|Bacteria,2GNRB@201174|Actinobacteria,4DD76@85008|Micromonosporales	201174|Actinobacteria	S	'Phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_669239_0	344747.PM8797T_29383	3.258e-86	292.0	COG3361@1|root,COG3361@2|Bacteria,2J2RP@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
CMS3_k127_6695858_0	1476583.DEIPH_ctg059orf0002	4.262e-130	426.0	COG0387@1|root,COG0387@2|Bacteria,1WJIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
CMS3_k127_6705096_1	383372.Rcas_3440	7.785e-48	178.0	COG3570@1|root,COG3570@2|Bacteria,2G7VJ@200795|Chloroflexi	200795|Chloroflexi	H	PFAM aminoglycoside hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
CMS3_k127_6705096_2	309801.trd_1553	3.941e-33	132.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi,27YEW@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS3_k127_6705096_3	926550.CLDAP_18620	4.26e-20	94.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
CMS3_k127_6705096_0	926550.CLDAP_18560	1.075e-233	732.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_6710117_0	324602.Caur_1031	3.023e-80	284.0	COG2936@1|root,COG2936@2|Bacteria,2G86S@200795|Chloroflexi	200795|Chloroflexi	S	X-Pro dipeptidyl-peptidase domain protein	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_6710117_4	1121938.AUDY01000012_gene3785	3.596e-08	63.0	2EAZJ@1|root,3350E@2|Bacteria,1VGFD@1239|Firmicutes,4HNX8@91061|Bacilli,3NEZQ@45667|Halobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3153
CMS3_k127_6710117_3	383372.Rcas_1070	9.313e-29	124.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi,375RP@32061|Chloroflexia	32061|Chloroflexia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS3_k127_6710117_1	926569.ANT_11680	1.097e-72	267.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
CMS3_k127_6710117_2	926550.CLDAP_01190	3.636e-59	235.0	COG2723@1|root,COG3307@1|root,COG2723@2|Bacteria,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	3.2.1.21	ko:K05350,ko:K21000	ko00460,ko00500,ko00940,ko01100,ko01110,ko02025,map00460,map00500,map00940,map01100,map01110,map02025	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH39	-	FlaA,Glyco_hydro_1,Glyco_hydro_42,Glyco_hydro_cc,Wzy_C
CMS3_k127_6719364_0	926569.ANT_04140	0.0	1189.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_6722936_0	1128421.JAGA01000004_gene2611	4.404e-52	188.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
CMS3_k127_6722936_1	1144275.COCOR_07974	4.7e-31	138.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
CMS3_k127_672308_2	1049564.TevJSym_ae00690	1.913e-09	66.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,1S3UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_672308_0	1122138.AQUZ01000004_gene897	1.498e-184	587.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4DPWR@85009|Propionibacteriales	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
CMS3_k127_672308_1	649747.HMPREF0083_01561	7.728e-122	396.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HV0C@91061|Bacilli,271MY@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS3_k127_6723359_0	1123368.AUIS01000014_gene2292	0.0	1080.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS3_k127_6723359_1	926569.ANT_25410	3.829e-240	755.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS3_k127_6723359_4	326427.Cagg_3625	2.607e-44	164.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi,375M5@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
CMS3_k127_6723359_3	156889.Mmc1_3283	3.307e-71	250.0	COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Inositol monophosphatase	suhB2	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS3_k127_6723359_2	1128421.JAGA01000004_gene2611	5.107e-118	389.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
CMS3_k127_6723574_7	1173264.KI913949_gene1725	9.273e-55	222.0	COG0265@1|root,COG1413@1|root,COG5635@1|root,COG0265@2|Bacteria,COG1413@2|Bacteria,COG5635@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2
CMS3_k127_6723574_3	479434.Sthe_1490	6.903e-128	428.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_6723574_10	1521187.JPIM01000052_gene3533	2.39e-35	140.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
CMS3_k127_6723574_14	1267534.KB906755_gene4065	1.86e-06	60.0	COG0823@1|root,COG0823@2|Bacteria,3Y445@57723|Acidobacteria,2JHUG@204432|Acidobacteriia	204432|Acidobacteriia	U	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PD40
CMS3_k127_6723574_11	42256.RradSPS_2112	5.137e-31	140.0	COG0842@1|root,COG0842@2|Bacteria,2ISVA@201174|Actinobacteria,4CQ5W@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_6723574_9	42256.RradSPS_2113	4.139e-39	164.0	COG0842@1|root,COG0842@2|Bacteria,2HG4S@201174|Actinobacteria,4CQ73@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_6723574_4	42256.RradSPS_2114	2.596e-107	357.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_6723574_5	2074.JNYD01000021_gene833	1.396e-72	274.0	COG2909@1|root,COG2909@2|Bacteria,2HQST@201174|Actinobacteria,4E9R0@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_6723574_1	1242864.D187_001830	9.692e-176	593.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS3_k127_6723574_2	1128421.JAGA01000002_gene1496	8.449e-142	462.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
CMS3_k127_6723574_0	479434.Sthe_0598	2.076e-199	665.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_6723574_6	765420.OSCT_2520	1.278e-64	242.0	COG4585@1|root,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_6723574_8	926550.CLDAP_30520	2.348e-51	190.0	COG2197@1|root,COG2197@2|Bacteria,2G8WD@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6723574_13	935261.JAGL01000031_gene309	5.359e-07	62.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria,43HQG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	40-residue YVTN family beta-propeller repeat	MA20_34510	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
CMS3_k127_6723574_12	671143.DAMO_1665	1.45e-09	64.0	COG5501@1|root,COG5501@2|Bacteria	2|Bacteria	-	-	MA20_34470	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
CMS3_k127_67250_1	1128421.JAGA01000001_gene2199	3.113e-14	79.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
CMS3_k127_67250_0	42256.RradSPS_0743	4.174e-42	173.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS3_k127_672870_0	1501230.ET33_02970	3.553e-140	460.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_6730993_1	194439.CT0086	3.475e-123	411.0	2CCJ8@1|root,335J6@2|Bacteria,1FES4@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6730993_0	479434.Sthe_0137	1.946e-125	415.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi,27Y3N@189775|Thermomicrobia	189775|Thermomicrobia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_6730993_2	926550.CLDAP_35990	6.471e-62	218.0	2F1C8@1|root,33UD3@2|Bacteria,2G8D9@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_6740586_0	1265505.ATUG01000001_gene4766	5.289e-126	413.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WIUM@28221|Deltaproteobacteria,2MI28@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_6740586_1	583345.Mmol_0574	1.736e-11	75.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,2KKDF@206350|Nitrosomonadales	206350|Nitrosomonadales	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_6762090_0	357808.RoseRS_2272	3.216e-198	634.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_6763086_1	926550.CLDAP_10440	2.052e-26	117.0	COG0438@1|root,COG0438@2|Bacteria,2G6KX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS3_k127_6763086_0	351160.LRC548	2.591e-50	190.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
CMS3_k127_6764849_0	1303518.CCALI_00843	3.943e-106	360.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6764849_1	1519464.HY22_13115	4.727e-36	145.0	COG5267@1|root,COG5267@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS3_k127_6765686_0	1123377.AUIV01000004_gene1896	5.243e-48	184.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales	135614|Xanthomonadales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS3_k127_6765686_2	316274.Haur_4849	3.19e-38	151.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,375TP@32061|Chloroflexia	32061|Chloroflexia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS3_k127_6765686_3	383372.Rcas_2165	2.158e-07	60.0	2C4GS@1|root,2ZTIR@2|Bacteria,2GBQH@200795|Chloroflexi,3761W@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
CMS3_k127_6765686_1	309801.trd_0658	3.914e-44	168.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,27XSF@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_6767428_5	1499967.BAYZ01000052_gene4665	1.402e-83	311.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_6767428_0	344747.PM8797T_05510	1.196e-312	973.0	COG3968@1|root,COG3968@2|Bacteria,2IXF6@203682|Planctomycetes	203682|Planctomycetes	S	Glutamine synthetase type III	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
CMS3_k127_6767428_4	471852.Tcur_2187	1.393e-150	501.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4EGU0@85012|Streptosporangiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_6767428_2	391625.PPSIR1_34717	8.761e-190	606.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42NXM@68525|delta/epsilon subdivisions,2WQMZ@28221|Deltaproteobacteria,2YY10@29|Myxococcales	28221|Deltaproteobacteria	C	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS3_k127_6767428_1	926550.CLDAP_37390	8.979e-290	903.0	COG0318@1|root,COG0318@2|Bacteria,2G7VC@200795|Chloroflexi	200795|Chloroflexi	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_6767428_12	1121937.AUHJ01000003_gene3293	1.008e-50	190.0	COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,1RMPM@1236|Gammaproteobacteria,466PW@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
CMS3_k127_6767428_13	298654.FraEuI1c_1902	4.783e-50	181.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria,4EVX4@85013|Frankiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_6767428_11	525904.Tter_2673	4.556e-53	199.0	COG3279@1|root,COG3839@1|root,COG3279@2|Bacteria,COG3839@2|Bacteria	2|Bacteria	P	tungstate ion transport	-	-	-	ko:K01990,ko:K07705,ko:K10112	ko02010,ko02020,map02010,map02020	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00254,M00491,M00492,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1,3.A.1.1	-	-	ABC_tran,LytTR,Response_reg
CMS3_k127_6767428_17	479434.Sthe_2098	5.993e-15	87.0	COG1668@1|root,COG1668@2|Bacteria,2GA92@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_6767428_6	1242864.D187_000933	1.17e-78	273.0	COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,43BX9@68525|delta/epsilon subdivisions,2X782@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
CMS3_k127_6767428_14	391625.PPSIR1_22054	5.21e-34	145.0	COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
CMS3_k127_6767428_9	1121912.AUHD01000005_gene1732	1.403e-59	215.0	COG1794@1|root,COG1794@2|Bacteria,4NQSH@976|Bacteroidetes,1I412@117743|Flavobacteriia	976|Bacteroidetes	M	Asp/Glu/Hydantoin racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
CMS3_k127_6767428_8	42256.RradSPS_0438	2.99e-69	252.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	3.4.21.66	ko:K08651,ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
CMS3_k127_6767428_3	42256.RradSPS_0437	2.284e-178	593.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
CMS3_k127_6767428_10	42256.RradSPS_0435	2.379e-55	201.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CMS3_k127_6767428_7	644282.Deba_0121	2.252e-74	253.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_6770696_1	443144.GM21_1075	2.343e-100	349.0	COG2204@1|root,COG3452@1|root,COG3852@1|root,COG2204@2|Bacteria,COG3452@2|Bacteria,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43BN0@68525|delta/epsilon subdivisions,2X702@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_6770696_2	1298864.AUEQ01000019_gene3562	5.303e-64	223.0	COG3871@1|root,COG3871@2|Bacteria,2IFC3@201174|Actinobacteria,238T2@1762|Mycobacteriaceae	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_6770696_3	930169.B5T_04338	5.4e-55	199.0	COG4977@1|root,COG4977@2|Bacteria,1RGI4@1224|Proteobacteria,1S4M9@1236|Gammaproteobacteria,1XJSR@135619|Oceanospirillales	135619|Oceanospirillales	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS3_k127_6770696_4	326297.Sama_2715	9.225e-52	193.0	COG2207@1|root,COG2207@2|Bacteria,1QV1Q@1224|Proteobacteria,1S81X@1236|Gammaproteobacteria,2QEJ2@267890|Shewanellaceae	1236|Gammaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_6770696_5	1185876.BN8_01704	1.975e-10	73.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS3_k127_6770696_6	631362.Thi970DRAFT_00260	2.039e-05	56.0	COG5464@1|root,COG5464@2|Bacteria,1R5BN@1224|Proteobacteria,1RRXI@1236|Gammaproteobacteria,1X0HQ@135613|Chromatiales	135613|Chromatiales	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6770696_0	761193.Runsl_1400	9.523e-122	397.0	COG2368@1|root,COG2368@2|Bacteria,4NKNT@976|Bacteroidetes	976|Bacteroidetes	Q	4-hydroxybutyryl-CoA dehydratase	abfD	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
CMS3_k127_6779287_0	765912.Thimo_0216	1.557e-12	81.0	COG0845@1|root,COG1357@1|root,COG2319@1|root,COG5635@1|root,COG0845@2|Bacteria,COG1357@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,1S1AJ@1236|Gammaproteobacteria,1WXXD@135613|Chromatiales	135613|Chromatiales	M	PFAM WD40 repeat, subgroup	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
CMS3_k127_6780101_0	438753.AZC_0688	1.603e-56	209.0	COG0412@1|root,COG0412@2|Bacteria,1R3DI@1224|Proteobacteria,2TVEH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_6780101_1	288000.BBta_5026	1.659e-54	203.0	COG0412@1|root,COG0412@2|Bacteria,1R3DI@1224|Proteobacteria,2TVEH@28211|Alphaproteobacteria,3JXJM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_6782022_1	1128421.JAGA01000003_gene3678	4.119e-84	309.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS3_k127_6782022_3	869210.Marky_0620	5.986e-35	148.0	COG2128@1|root,COG2128@2|Bacteria,1WJ8T@1297|Deinococcus-Thermus	2|Bacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	CMD,DUF3179
CMS3_k127_6782022_0	1297569.MESS2_610021	1.153e-99	342.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2U28M@28211|Alphaproteobacteria,43QZ7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_6782022_2	670487.Ocepr_0115	1.836e-72	254.0	COG0697@1|root,COG0697@2|Bacteria,1WKUM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6782022_4	765420.OSCT_2895	2.039e-17	89.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
CMS3_k127_6789320_5	1077972.ARGLB_058_00620	1.003e-09	61.0	COG0520@1|root,COG0520@2|Bacteria,2GJA4@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class v	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_6789320_3	877455.Metbo_0358	1.021e-13	75.0	COG4063@1|root,arCOG03221@2157|Archaea,2XWSE@28890|Euryarchaeota,23PC8@183925|Methanobacteria	183925|Methanobacteria	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
CMS3_k127_6789320_1	754436.JCM19237_2168	4.305e-27	123.0	COG0739@1|root,COG0739@2|Bacteria,1QJWI@1224|Proteobacteria,1THY9@1236|Gammaproteobacteria,1XXW6@135623|Vibrionales	135623|Vibrionales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_6789320_2	1273538.G159_04940	4.185e-15	79.0	2DNVA@1|root,32ZBE@2|Bacteria,1W480@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6789320_0	552811.Dehly_1516	6.751e-110	371.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi	200795|Chloroflexi	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_6790154_2	862908.BMS_2504	2.711e-14	78.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
CMS3_k127_6790154_1	867845.KI911784_gene3251	2.128e-19	93.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_6790154_0	1313172.YM304_26920	1.969e-48	194.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,2GISS@201174|Actinobacteria,4CMS6@84992|Acidimicrobiia	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_6797899_0	861299.J421_2387	4.903e-66	250.0	COG1680@1|root,COG1680@2|Bacteria,1ZV34@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_6797899_3	247639.MGP2080_13663	8.674e-10	71.0	COG3187@1|root,COG3187@2|Bacteria,1NGG1@1224|Proteobacteria,1T10Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	META domain	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
CMS3_k127_6797899_2	1120968.AUBX01000012_gene2865	2.618e-21	108.0	COG3187@1|root,COG3187@2|Bacteria,4PKCG@976|Bacteroidetes,47SY5@768503|Cytophagia	976|Bacteroidetes	O	Domain of unknown function (DUF4377)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4377,META
CMS3_k127_6797899_1	43989.cce_1421	3.117e-61	221.0	COG3208@1|root,COG3208@2|Bacteria,1G16V@1117|Cyanobacteria,3KG55@43988|Cyanothece	1117|Cyanobacteria	Q	Thioesterase domain	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Thioesterase
CMS3_k127_6801279_10	1293054.HSACCH_00449	1.036e-14	78.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6801279_8	926550.CLDAP_13510	3.87e-17	84.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6801279_0	1283287.KB822585_gene2690	4.378e-100	336.0	COG2141@1|root,COG2141@2|Bacteria,2IEM9@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
CMS3_k127_6801279_6	760192.Halhy_5223	1.868e-31	130.0	COG0251@1|root,COG0667@1|root,COG0251@2|Bacteria,COG0667@2|Bacteria,4NPT2@976|Bacteroidetes,1IYB6@117747|Sphingobacteriia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
CMS3_k127_6801279_1	555088.DealDRAFT_0158	3.04e-75	258.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,42KPH@68298|Syntrophomonadaceae	186801|Clostridia	S	Haemolysin-III related	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS3_k127_6801279_12	551789.ATVJ01000001_gene2478	0.0001846	54.0	COG2352@1|root,COG2352@2|Bacteria,1PUW3@1224|Proteobacteria,2V6E4@28211|Alphaproteobacteria,43WWC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	Phosphoenolpyruvate carboxylase	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS3_k127_6801279_5	1480694.DC28_13515	4.944e-36	151.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	5.99.1.3	ko:K02470,ko:K03833	-	-	-	-	ko00000,ko01000,ko03012,ko03032,ko03400	-	-	-	HATPase_c,HTH_20
CMS3_k127_6801279_9	926569.ANT_28270	9.825e-15	78.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS3_k127_6801279_4	326427.Cagg_3759	7.238e-47	175.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_6801279_7	326427.Cagg_3758	4.915e-25	119.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6801279_3	1380394.JADL01000004_gene6003	1.689e-48	182.0	COG0546@1|root,COG0546@2|Bacteria,1RB0Z@1224|Proteobacteria,2U5DF@28211|Alphaproteobacteria,2JTK3@204441|Rhodospirillales	204441|Rhodospirillales	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_6801279_11	1476583.DEIPH_ctg094orf0006	0.000127	51.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS3_k127_6801279_2	309801.trd_0073	1.751e-60	218.0	COG2234@1|root,COG2234@2|Bacteria,2G9MK@200795|Chloroflexi,27XKJ@189775|Thermomicrobia	189775|Thermomicrobia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_6803924_0	318996.AXAZ01000037_gene1379	8.807e-144	460.0	COG2133@1|root,COG2133@2|Bacteria,1R8DY@1224|Proteobacteria,2U4BZ@28211|Alphaproteobacteria,3JXE5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6803924_2	1137799.GZ78_14485	1.392e-68	237.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
CMS3_k127_6803924_3	680198.SCAB_77561	1.172e-07	59.0	COG3631@1|root,COG3631@2|Bacteria,2IIFN@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_6803924_4	796620.VIBC2010_19940	0.0005155	46.0	COG3631@1|root,COG3631@2|Bacteria,1RE9H@1224|Proteobacteria,1S940@1236|Gammaproteobacteria,1XWP4@135623|Vibrionales	135623|Vibrionales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_6803924_5	1379270.AUXF01000005_gene354	0.0005311	42.0	COG3525@1|root,COG3525@2|Bacteria,1ZT3V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
CMS3_k127_6803924_1	1380347.JNII01000006_gene1591	1.461e-82	292.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4ETX1@85013|Frankiales	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
CMS3_k127_6808898_5	926569.ANT_13340	5.055e-82	294.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS3_k127_6808898_8	926550.CLDAP_16790	1.034e-60	216.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_6808898_10	867845.KI911784_gene3573	3.727e-28	118.0	COG1694@1|root,COG1694@2|Bacteria,2G9Y9@200795|Chloroflexi,377WH@32061|Chloroflexia	32061|Chloroflexia	F	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CMS3_k127_6808898_1	485913.Krac_9125	2.26e-133	434.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_6808898_3	926569.ANT_13260	1.232e-112	378.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
CMS3_k127_6808898_7	662479.C440_00610	6.274e-66	239.0	arCOG09395@1|root,arCOG09395@2157|Archaea,2XTUR@28890|Euryarchaeota,23S6T@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS3_k127_6808898_11	309801.trd_0184	6.318e-05	53.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,2G99E@200795|Chloroflexi,27XPH@189775|Thermomicrobia	189775|Thermomicrobia	MT	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
CMS3_k127_6808898_6	1304880.JAGB01000004_gene1478	1.627e-75	265.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS3_k127_6808898_4	1009370.ALO_00305	1.577e-85	295.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4H32Z@909932|Negativicutes	909932|Negativicutes	P	oligopeptide transport system permease protein OppB	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS3_k127_6808898_9	1128421.JAGA01000002_gene830	7.269e-55	214.0	COG4166@1|root,COG4166@2|Bacteria,2NQQP@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_6808898_0	479434.Sthe_0389	1.253e-145	470.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,27XY8@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_6808898_2	1128421.JAGA01000002_gene833	3.324e-125	410.0	COG0444@1|root,COG0444@2|Bacteria,2NQAA@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS3_k127_6812356_6	526227.Mesil_2534	7.696e-16	82.0	COG2355@1|root,COG2355@2|Bacteria,1WJQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS3_k127_6812356_3	309801.trd_1666	2.225e-86	295.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,27XEG@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
CMS3_k127_6812356_5	882.DVU_2774	3.945e-38	147.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42R80@68525|delta/epsilon subdivisions,2WMW6@28221|Deltaproteobacteria,2MARF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_6812356_2	383372.Rcas_2064	7.084e-99	333.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS3_k127_6812356_4	33178.CADATEAP00004711	2.524e-67	243.0	KOG0271@1|root,KOG0271@2759|Eukaryota,3AGU6@33154|Opisthokonta,3Q4J3@4751|Fungi,3RMSV@4890|Ascomycota,20U9D@147545|Eurotiomycetes,3SE7S@5042|Eurotiales	4751|Fungi	G	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,PNP_UDP_1,WD40
CMS3_k127_6812356_1	573413.Spirs_3648	7.05e-117	382.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	thuG	-	-	ko:K02026,ko:K10238	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
CMS3_k127_6812356_0	926550.CLDAP_26510	1.437e-131	430.0	COG1175@1|root,COG1175@2|Bacteria,2G8HC@200795|Chloroflexi	200795|Chloroflexi	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10237	ko02010,map02010	M00204	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.17	-	-	BPD_transp_1
CMS3_k127_681755_0	1463903.JOIZ01000018_gene597	9.141e-111	386.0	COG0318@1|root,COG1020@1|root,COG3321@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,COG3321@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt
CMS3_k127_6825398_2	316274.Haur_0008	4.783e-50	181.0	COG2110@1|root,COG2110@2|Bacteria,2GAYN@200795|Chloroflexi,377JN@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_6825398_1	1163408.UU9_01284	5.113e-64	226.0	COG0454@1|root,COG0454@2|Bacteria,1QUHE@1224|Proteobacteria,1T1Z5@1236|Gammaproteobacteria,1X6XV@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_6825398_3	663278.Ethha_0113	3.739e-19	93.0	2ERRQ@1|root,33JAW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6825398_0	502025.Hoch_6290	5.68e-106	351.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,42RA9@68525|delta/epsilon subdivisions,2WQIZ@28221|Deltaproteobacteria,2Z0UK@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
CMS3_k127_6829627_0	452637.Oter_2033	4.044e-138	454.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
CMS3_k127_6832321_3	926550.CLDAP_01280	5.309e-82	287.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6832321_6	1173026.Glo7428_0674	4.715e-41	158.0	COG1670@1|root,COG1670@2|Bacteria,1GEB6@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_6832321_1	765420.OSCT_2888	2.382e-163	574.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi,37651@32061|Chloroflexia	32061|Chloroflexia	S	Alpha-2-macroglobulin family	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5
CMS3_k127_6832321_2	404380.Gbem_2069	1.577e-95	349.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG3852@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,1NWNJ@1224|Proteobacteria,43CGS@68525|delta/epsilon subdivisions,2X7RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,Response_reg
CMS3_k127_6832321_5	330214.NIDE3570	3.622e-44	168.0	COG2203@1|root,COG3437@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
CMS3_k127_6832321_4	644282.Deba_1323	5.824e-60	231.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_6832321_7	1121033.AUCF01000008_gene5761	0.0002478	46.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TXJ2@28211|Alphaproteobacteria,2JPEA@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_7,Response_reg
CMS3_k127_6832321_0	1041930.Mtc_1018	4.092e-200	642.0	COG0525@1|root,arCOG00808@2157|Archaea,2XSXQ@28890|Euryarchaeota,2N93W@224756|Methanomicrobia	224756|Methanomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1976	Anticodon_1,tRNA-synt_1
CMS3_k127_6834969_0	926692.AZYG01000036_gene2504	5.359e-151	492.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3WBKG@53433|Halanaerobiales	186801|Clostridia	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
CMS3_k127_6844596_3	313598.MED152_07970	3.378e-25	124.0	COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,4NMB8@976|Bacteroidetes,1I0EW@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG
CMS3_k127_6844596_2	1408473.JHXO01000015_gene1906	2.426e-38	168.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
CMS3_k127_6844596_1	439292.Bsel_1695	4.056e-50	207.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26NEC@186821|Sporolactobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_6844596_0	1463921.JODF01000002_gene3096	2.757e-131	468.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
CMS3_k127_6853906_10	517418.Ctha_0137	1.31e-32	127.0	COG2048@1|root,COG2048@2|Bacteria	2|Bacteria	C	Heterodisulfide reductase, subunit B	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS3_k127_6853906_2	882083.SacmaDRAFT_1923	1.714e-145	468.0	COG1148@1|root,COG1148@2|Bacteria,2IQQS@201174|Actinobacteria	201174|Actinobacteria	C	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_6853906_7	882083.SacmaDRAFT_1924	7.122e-53	197.0	2DPCA@1|root,331H2@2|Bacteria,2HCYY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6853906_1	309801.trd_0150	1.76e-188	598.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS3_k127_6853906_5	525909.Afer_0969	1.846e-63	227.0	COG2086@1|root,COG2086@2|Bacteria,2H4H4@201174|Actinobacteria,4CNJD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_6853906_3	882083.SacmaDRAFT_1932	2.697e-90	308.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DY2C@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
CMS3_k127_6853906_0	517418.Ctha_0130	1.021e-228	728.0	COG0247@1|root,COG0247@2|Bacteria,1FDTD@1090|Chlorobi	1090|Chlorobi	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Nitrate_red_gam
CMS3_k127_6853906_11	882083.SacmaDRAFT_1935	6.315e-20	94.0	28XG9@1|root,2ZJDS@2|Bacteria,2HAXA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6853906_6	309801.trd_0144	7.297e-55	195.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_6853906_8	309801.trd_0143	3.049e-41	156.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_6853906_9	517418.Ctha_0129	9.421e-36	141.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_6853906_4	517418.Ctha_0128	5.16e-78	267.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,DUF116
CMS3_k127_6868836_12	316274.Haur_1707	1.066e-08	66.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G6X4@200795|Chloroflexi,37715@32061|Chloroflexia	32061|Chloroflexia	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
CMS3_k127_6868836_4	357808.RoseRS_1505	6.142e-135	436.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CMS3_k127_6868836_11	401053.AciPR4_1666	3.532e-10	69.0	COG2717@1|root,COG2717@2|Bacteria,3Y58Y@57723|Acidobacteria,2JJTH@204432|Acidobacteriia	204432|Acidobacteriia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
CMS3_k127_6868836_9	357808.RoseRS_1504	1.136e-23	104.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
CMS3_k127_6868836_0	485913.Krac_11208	1.863e-176	581.0	COG2366@1|root,COG2366@2|Bacteria,2G63N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS3_k127_6868836_1	926550.CLDAP_27570	4.805e-174	552.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6868836_5	326427.Cagg_1901	1.035e-104	353.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_6868836_3	926569.ANT_16960	6.684e-151	488.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS3_k127_6868836_6	1128421.JAGA01000001_gene2396	4.153e-91	311.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_6868836_2	926569.ANT_16920	8.388e-169	543.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
CMS3_k127_6868836_8	926550.CLDAP_15780	9.67e-28	119.0	COG0457@1|root,COG0457@2|Bacteria	926550.CLDAP_15780|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6868836_10	316274.Haur_1905	1.72e-15	89.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,376VY@32061|Chloroflexia	32061|Chloroflexia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_6868836_7	485913.Krac_10258	2.147e-52	193.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS3_k127_6878462_1	1303518.CCALI_01253	1.515e-53	194.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
CMS3_k127_6878462_0	357808.RoseRS_0927	2.385e-169	544.0	COG1404@1|root,COG1404@2|Bacteria,2G80X@200795|Chloroflexi,375FY@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_6879043_1	1382306.JNIM01000001_gene1915	1.142e-39	156.0	COG0223@1|root,COG0223@2|Bacteria,2G6VD@200795|Chloroflexi	200795|Chloroflexi	J	PFAM formyl transferase domain protein	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
CMS3_k127_6879043_0	357808.RoseRS_2229	1.283e-67	259.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6879043_2	1395571.TMS3_0113755	2.149e-31	125.0	COG0388@1|root,COG0388@2|Bacteria,1RC9F@1224|Proteobacteria,1SRPK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS3_k127_6885264_7	1298863.AUEP01000009_gene52	5.243e-40	150.0	COG5012@1|root,COG5012@2|Bacteria,2IEGQ@201174|Actinobacteria,4DTAH@85009|Propionibacteriales	201174|Actinobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
CMS3_k127_6885264_4	1303518.CCALI_00702	3.003e-68	244.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_6885264_0	1298863.AUEP01000009_gene50	4.745e-171	556.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,2HE4H@201174|Actinobacteria,4DTK0@85009|Propionibacteriales	201174|Actinobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS3_k127_6885264_1	926550.CLDAP_19790	7.176e-131	424.0	COG1410@1|root,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_6885264_9	1208323.B30_06026	4.114e-08	58.0	2CDZD@1|root,32RYT@2|Bacteria,1N0AT@1224|Proteobacteria,2UBTM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Virulence factor	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
CMS3_k127_6885264_8	935261.JAGL01000002_gene1254	1.354e-19	95.0	2CDZD@1|root,32RYT@2|Bacteria,1N0AT@1224|Proteobacteria,2UBTM@28211|Alphaproteobacteria,43KJ2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Virulence factor	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
CMS3_k127_6885264_6	926550.CLDAP_19770	8.788e-44	165.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
CMS3_k127_6885264_5	926550.CLDAP_19780	1.286e-62	218.0	COG0685@1|root,COG0685@2|Bacteria,2G7NU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_6885264_3	926550.CLDAP_19780	3.539e-73	250.0	COG0685@1|root,COG0685@2|Bacteria,2G7NU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_6885264_2	485913.Krac_5920	2.138e-88	300.0	COG0641@1|root,COG0641@2|Bacteria,2G74V@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SPASM
CMS3_k127_6890151_1	643473.KB235930_gene2586	5.158e-112	368.0	COG0330@1|root,COG0330@2|Bacteria,1G1GC@1117|Cyanobacteria,1HIDC@1161|Nostocales	1117|Cyanobacteria	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_6890151_2	448385.sce2073	8.958e-74	282.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2Z01S@29|Myxococcales	28221|Deltaproteobacteria	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
CMS3_k127_6890151_0	384765.SIAM614_08384	3.347e-156	512.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TTUP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	MA20_07595	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos
CMS3_k127_6906096_2	926569.ANT_06180	4.95e-88	309.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
CMS3_k127_6906096_6	316274.Haur_1550	7.26e-20	96.0	COG3937@1|root,COG3937@2|Bacteria,2G7GR@200795|Chloroflexi,375WV@32061|Chloroflexia	32061|Chloroflexia	S	Poly(hydroxyalcanoate) granule associated protein (phasin)	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
CMS3_k127_6906096_5	326427.Cagg_0064	1.135e-33	137.0	COG3937@1|root,COG5394@1|root,COG3937@2|Bacteria,COG5394@2|Bacteria,2G77C@200795|Chloroflexi,375VS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM PHA accumulation regulator DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
CMS3_k127_6906096_7	357808.RoseRS_2673	1.862e-18	90.0	COG3467@1|root,COG3467@2|Bacteria,2G729@200795|Chloroflexi,377IP@32061|Chloroflexia	32061|Chloroflexia	S	PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_6906096_3	1128421.JAGA01000003_gene3559	9.723e-79	278.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_6906096_0	1501230.ET33_24200	4.678e-240	757.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26QA9@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS3_k127_6906096_4	1501230.ET33_18765	1.573e-71	248.0	COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,26WYG@186822|Paenibacillaceae	91061|Bacilli	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS3_k127_6906096_1	926569.ANT_30500	3.387e-224	727.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
CMS3_k127_6914554_0	1410619.SRDD_38190	3.193e-59	211.0	COG0135@1|root,COG0503@1|root,COG0135@2|Bacteria,COG0503@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS3_k127_6917173_0	479434.Sthe_3409	3.934e-179	573.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_6917173_3	1121456.ATVA01000012_gene2569	1.266e-87	302.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS3_k127_6917173_6	479434.Sthe_3411	4.791e-46	176.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	MetW,Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_6917173_1	324602.Caur_3056	1.921e-128	422.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_6917173_10	1382306.JNIM01000001_gene847	1.727e-06	58.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene847|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6917173_4	266117.Rxyl_2074	1.341e-83	287.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4CQEA@84995|Rubrobacteria	84995|Rubrobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CMS3_k127_6917173_5	926550.CLDAP_10540	4.05e-48	182.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_6917173_7	498761.HM1_2443	4.021e-31	127.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia	186801|Clostridia	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS3_k127_6917173_2	926550.CLDAP_16370	9.239e-113	392.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
CMS3_k127_6917173_8	1121428.DESHY_60272___1	1.509e-24	107.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
CMS3_k127_6922677_0	649638.Trad_0147	0.0	1267.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_6922677_1	706587.Desti_1327	3.635e-143	464.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2MQCX@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
CMS3_k127_6939936_0	498761.HM1_1039	1.188e-218	688.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS3_k127_6942362_3	926569.ANT_03110	1.779e-26	120.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_6942362_1	1382306.JNIM01000001_gene722	3.58e-52	192.0	COG0664@1|root,COG0664@2|Bacteria,2G6YS@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_6942362_0	1118054.CAGW01000010_gene3935	9.267e-100	336.0	COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli,26VVD@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_6942362_2	316274.Haur_3681	6.558e-49	197.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GGDEF,HD,TPR_12
CMS3_k127_6954177_4	880071.Fleli_4017	2.3e-12	71.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	GGDEF,HATPase_c,HisKA,cNMP_binding
CMS3_k127_6954177_3	926560.KE387027_gene603	1.061e-46	174.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS3_k127_6954177_0	1449080.JQMV01000003_gene1600	6.094e-71	258.0	COG1653@1|root,COG1653@2|Bacteria,1WKXI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1
CMS3_k127_6954177_1	1128421.JAGA01000003_gene3490	1.19e-68	239.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
CMS3_k127_6954177_2	926550.CLDAP_25050	1.501e-56	203.0	COG0284@1|root,COG0461@1|root,COG0284@2|Bacteria,COG0461@2|Bacteria,2G692@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS3_k127_6967499_0	1125863.JAFN01000001_gene1778	2.86e-91	321.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_oxidored,Fer4,Fer4_7,NAD_binding_8,Pyr_redox_2,Response_reg
CMS3_k127_6967499_1	1121428.DESHY_110412___1	3.484e-12	67.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,260T4@186807|Peptococcaceae	186801|Clostridia	C	heterodisulfide reductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS3_k127_6968896_3	1144275.COCOR_05185	4.066e-12	78.0	COG0596@1|root,COG0596@2|Bacteria,1R4N4@1224|Proteobacteria,434SV@68525|delta/epsilon subdivisions,2WZ3Y@28221|Deltaproteobacteria,2Z19T@29|Myxococcales	28221|Deltaproteobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_6968896_0	926550.CLDAP_32590	9.32e-160	515.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi	2|Bacteria	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
CMS3_k127_6968896_1	357808.RoseRS_1949	5.245e-49	190.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
CMS3_k127_6968896_2	1121918.ARWE01000001_gene3198	1.025e-22	111.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43DFM@68525|delta/epsilon subdivisions,2X8MI@28221|Deltaproteobacteria,43UST@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_6969813_0	649638.Trad_1384	2.897e-128	428.0	COG2041@1|root,COG2041@2|Bacteria,1WI25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS3_k127_6969882_5	383372.Rcas_1314	2.479e-08	57.0	2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6969882_2	292459.STH876	3.237e-31	128.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
CMS3_k127_6969882_1	316274.Haur_2242	6.085e-68	252.0	COG2843@1|root,COG2843@2|Bacteria,2GB5U@200795|Chloroflexi,377DF@32061|Chloroflexia	32061|Chloroflexia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS3_k127_6969882_3	883103.HMPREF9703_01466	3.722e-29	128.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,27FNF@186828|Carnobacteriaceae	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	vanYB	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
CMS3_k127_6969882_0	1382356.JQMP01000001_gene805	1.744e-177	569.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi,27XUU@189775|Thermomicrobia	189775|Thermomicrobia	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS3_k127_6972894_0	1128421.JAGA01000001_gene2146	6.527e-97	338.0	2CA5R@1|root,2Z81H@2|Bacteria,2NRJU@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
CMS3_k127_697370_0	1121377.KB906400_gene1412	7.082e-86	310.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_697370_1	316067.Geob_2070	8.986e-64	225.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,42VMX@68525|delta/epsilon subdivisions,2WS5W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS3_k127_697370_3	1121382.JQKG01000021_gene1942	3.601e-22	99.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS3_k127_697370_2	391625.PPSIR1_41609	4.543e-31	126.0	KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_6977503_0	1336249.JADW01000009_gene1560	2.507e-21	98.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2U3N3@28211|Alphaproteobacteria,4B738@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_6977503_1	880073.Calab_2669	2.46e-17	93.0	COG0438@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,2NPQ4@2323|unclassified Bacteria	2|Bacteria	J	Glycosyltransferase like family 2	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_23
CMS3_k127_6981038_0	383372.Rcas_3083	2.163e-136	441.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi,3756K@32061|Chloroflexia	32061|Chloroflexia	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_6981038_1	926569.ANT_19500	9.89e-48	176.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	rfaH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
CMS3_k127_6981038_2	926550.CLDAP_39660	4.236e-17	95.0	COG0651@1|root,COG0651@2|Bacteria,2G9I2@200795|Chloroflexi	200795|Chloroflexi	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
CMS3_k127_6997714_5	552811.Dehly_0564	2.558e-20	96.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_6997714_4	479434.Sthe_2667	5.306e-40	163.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_6997714_1	448385.sce1866	2.382e-125	413.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,42UK8@68525|delta/epsilon subdivisions,2WQG7@28221|Deltaproteobacteria,2YXKW@29|Myxococcales	28221|Deltaproteobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
CMS3_k127_6997714_0	555079.Toce_0822	6.768e-151	490.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS3_k127_6997714_2	1121405.dsmv_2257	4.399e-94	317.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42P9B@68525|delta/epsilon subdivisions,2WMCP@28221|Deltaproteobacteria,2MMBX@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_6997714_3	1068980.ARVW01000001_gene1578	8.171e-78	263.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4DZEJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_6998410_0	1121377.KB906404_gene2877	1.497e-112	391.0	COG0515@1|root,COG0515@2|Bacteria,1WIDK@1297|Deinococcus-Thermus	1121377.KB906404_gene2877|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6998410_1	1122918.KB907247_gene4932	2.533e-51	186.0	COG2746@1|root,COG2746@2|Bacteria,1V2QD@1239|Firmicutes,4HE0G@91061|Bacilli,26QGC@186822|Paenibacillaceae	91061|Bacilli	V	aminoglycoside	yokD	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
CMS3_k127_7002767_2	765420.OSCT_2505	1.782e-24	114.0	COG2834@1|root,COG2834@2|Bacteria,2G9H4@200795|Chloroflexi,377AS@32061|Chloroflexia	32061|Chloroflexia	M	Domain of unknown function (DUF4367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
CMS3_k127_7002767_1	1524467.IV04_20775	1.32e-37	153.0	COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,1RRBB@1236|Gammaproteobacteria,3ZZN3@613|Serratia	1236|Gammaproteobacteria	S	beta-lactamase	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_7002767_0	926550.CLDAP_29060	1.264e-113	376.0	COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Squalene phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS3_k127_7010975_0	56110.Oscil6304_6039	9.132e-154	498.0	COG0457@1|root,COG2319@1|root,COG4995@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria,COG4995@2|Bacteria,1GC4U@1117|Cyanobacteria,1HEM7@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,WD40
CMS3_k127_7010975_9	197221.22294959	0.0003622	52.0	COG1716@1|root,COG1716@2|Bacteria,1G6TU@1117|Cyanobacteria	1117|Cyanobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_7010975_8	1382356.JQMP01000004_gene416	7.269e-13	76.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,27YBI@189775|Thermomicrobia	189775|Thermomicrobia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_7010975_6	765420.OSCT_1592	1.859e-43	175.0	COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,37557@32061|Chloroflexia	32061|Chloroflexia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
CMS3_k127_7010975_5	525904.Tter_1376	3.891e-72	263.0	COG0768@1|root,COG0768@2|Bacteria,2NQV0@2323|unclassified Bacteria	2|Bacteria	M	Penicillin binding protein transpeptidase domain	pbpA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
CMS3_k127_7010975_4	714943.Mucpa_3589	8.158e-79	278.0	COG1835@1|root,COG1835@2|Bacteria,4NIVR@976|Bacteroidetes,1ITNG@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS3_k127_7010975_2	1146883.BLASA_1057	3.612e-116	401.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EVZ3@85013|Frankiales	201174|Actinobacteria	T	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_7010975_3	485913.Krac_9651	7.868e-82	278.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	2|Bacteria	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_7010975_1	1463921.JODF01000002_gene3096	7.536e-152	527.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
CMS3_k127_7010975_7	1499967.BAYZ01000028_gene1290	1.143e-42	172.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_7026705_5	357808.RoseRS_4105	8.079e-45	165.0	COG0411@1|root,COG0411@2|Bacteria,2GABI@200795|Chloroflexi,376AR@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_7026705_4	316274.Haur_3805	6.022e-101	344.0	COG0683@1|root,COG0683@2|Bacteria,2G904@200795|Chloroflexi,3754R@32061|Chloroflexia	32061|Chloroflexia	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS3_k127_7026705_1	326427.Cagg_0368	5.016e-149	479.0	COG2267@1|root,COG2267@2|Bacteria,2G5ZY@200795|Chloroflexi,376GK@32061|Chloroflexia	32061|Chloroflexia	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS3_k127_7026705_0	1205680.CAKO01000010_gene3832	3.522e-167	541.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JPCT@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_7026705_2	748247.AZKH_0195	9.787e-146	475.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_7026705_6	479434.Sthe_3270	3.001e-06	59.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7026705_3	324602.Caur_3619	3.671e-116	391.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
CMS3_k127_7030177_0	1385935.N836_20445	1.341e-152	516.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
CMS3_k127_7031394_1	1449050.JNLE01000003_gene82	2.405e-22	99.0	COG4587@1|root,COG4587@2|Bacteria,1VDUN@1239|Firmicutes	1239|Firmicutes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS3_k127_7031394_0	324602.Caur_3312	2.538e-109	362.0	COG4586@1|root,COG4586@2|Bacteria,2G88B@200795|Chloroflexi,376NY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7031394_2	1226325.HMPREF1548_02182	0.0001024	46.0	COG0789@1|root,COG0789@2|Bacteria,1TQ78@1239|Firmicutes,247ZI@186801|Clostridia,36F7F@31979|Clostridiaceae	186801|Clostridia	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_703332_2	309801.trd_1592	6.672e-72	253.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi,27XHV@189775|Thermomicrobia	189775|Thermomicrobia	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS3_k127_703332_3	926550.CLDAP_31380	2.521e-58	213.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
CMS3_k127_703332_1	926550.CLDAP_07940	2.709e-84	296.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_703332_0	926569.ANT_04080	7.951e-221	699.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
CMS3_k127_703332_4	35754.JNYJ01000007_gene2933	3.251e-24	117.0	COG1404@1|root,COG2133@1|root,COG3291@1|root,COG4775@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4775@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD
CMS3_k127_7041738_6	479434.Sthe_0028	2.114e-65	229.0	COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi,27YV7@189775|Thermomicrobia	189775|Thermomicrobia	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
CMS3_k127_7041738_0	479434.Sthe_1794	9.905e-194	609.0	COG1960@1|root,COG1960@2|Bacteria,2G815@200795|Chloroflexi,27Z4U@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7041738_2	216591.BCAS0021	1.236e-153	494.0	COG1804@1|root,COG1804@2|Bacteria,1MU4A@1224|Proteobacteria,2VKDA@28216|Betaproteobacteria,1JZU6@119060|Burkholderiaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.22	ko:K18289	ko00660,map00660	-	R02407,R03154	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_transf_3
CMS3_k127_7041738_4	926569.ANT_30250	2.792e-121	402.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_7041738_5	479434.Sthe_1792	8.887e-80	268.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
CMS3_k127_7041738_7	1449076.JOOE01000001_gene1983	2.238e-55	201.0	COG3217@1|root,COG3217@2|Bacteria,1Q80R@1224|Proteobacteria,2VE68@28211|Alphaproteobacteria,2K30Y@204457|Sphingomonadales	204457|Sphingomonadales	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MOSC_N
CMS3_k127_7041738_1	926550.CLDAP_39020	2.651e-157	505.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi	200795|Chloroflexi	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS3_k127_7041738_3	479434.Sthe_0598	6.196e-136	475.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_7041738_8	248742.XP_005651232.1	0.0005723	46.0	COG2217@1|root,KOG0207@2759|Eukaryota,37HKS@33090|Viridiplantae,34JKK@3041|Chlorophyta	3041|Chlorophyta	P	Heavy-metal-associated domain	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_7045211_0	536227.CcarbDRAFT_4777	4.376e-87	295.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
CMS3_k127_7045211_4	557599.MKAN_01345	1.019e-17	86.0	COG0062@1|root,COG0062@2|Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS3_k127_7045211_5	521011.Mpal_1970	1.89e-15	85.0	COG3291@1|root,arCOG02498@1|root,arCOG02526@1|root,arCOG02498@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,2Y30D@28890|Euryarchaeota,2NAGI@224756|Methanomicrobia	224756|Methanomicrobia	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	NosD,PKD
CMS3_k127_7045211_8	756499.Desde_2281	3.245e-05	54.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,26432@186807|Peptococcaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
CMS3_k127_7045211_3	1209984.BN978_00762	1.435e-38	148.0	COG1595@1|root,COG1765@1|root,COG1595@2|Bacteria,COG1765@2|Bacteria,2GJIZ@201174|Actinobacteria,235TD@1762|Mycobacteriaceae	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7045211_2	1121918.ARWE01000001_gene3117	7.477e-50	187.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,43VJ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CMS3_k127_7045211_7	666684.AfiDRAFT_1555	1.686e-11	71.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2UC5S@28211|Alphaproteobacteria,3K0TI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS3_k127_7045211_6	1123320.KB889562_gene6867	8.157e-13	79.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
CMS3_k127_7045211_1	326427.Cagg_3225	5.403e-85	302.0	COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi,374ZA@32061|Chloroflexia	32061|Chloroflexia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS3_k127_704698_0	1267534.KB906756_gene667	3.438e-92	332.0	COG0642@1|root,COG2199@1|root,COG2203@1|root,COG3292@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PilZ,Response_reg,Y_Y_Y
CMS3_k127_704698_3	1157490.EL26_20055	5.772e-10	69.0	2DPKD@1|root,332HI@2|Bacteria,1VHUB@1239|Firmicutes,4IS0F@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_704698_1	452652.KSE_34560	8.101e-69	249.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,2M1CJ@2063|Kitasatospora	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_704698_2	926550.CLDAP_02680	1.109e-47	192.0	COG3170@1|root,COG3292@1|root,COG3170@2|Bacteria,COG3292@2|Bacteria,2G7P1@200795|Chloroflexi	200795|Chloroflexi	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
CMS3_k127_7056844_2	935836.JAEL01000004_gene2475	7.173e-38	144.0	COG0454@1|root,COG0454@2|Bacteria,1UHNV@1239|Firmicutes,4IS4R@91061|Bacilli,1ZS7G@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_7056844_3	1089548.KI783301_gene1439	1.357e-08	65.0	COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
CMS3_k127_7056844_1	33876.JNXY01000045_gene1934	2.35e-75	263.0	COG0596@1|root,COG0596@2|Bacteria,2IFCI@201174|Actinobacteria,4DC31@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_7056844_0	357808.RoseRS_0911	2.272e-167	533.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi,376DI@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CMS3_k127_7057678_0	357808.RoseRS_3121	4.123e-69	249.0	COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi,374XV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_7057678_1	340.xcc-b100_2579	2.482e-63	231.0	COG0438@1|root,COG0438@2|Bacteria,1PDQY@1224|Proteobacteria,1SE53@1236|Gammaproteobacteria,1X59A@135614|Xanthomonadales	135614|Xanthomonadales	M	Hexosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_7057678_2	391587.KAOT1_19422	2.475e-27	128.0	COG2755@1|root,COG2755@2|Bacteria,4P1HT@976|Bacteroidetes,1I7G5@117743|Flavobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_7057678_3	765420.OSCT_2442	5.406e-14	85.0	COG1807@1|root,COG1807@2|Bacteria,2GAAY@200795|Chloroflexi,374TV@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7060783_1	926550.CLDAP_35630	3.216e-131	426.0	COG0714@1|root,COG0714@2|Bacteria,2G87C@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_7060783_2	926550.CLDAP_35640	2.82e-76	271.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_7060783_3	357808.RoseRS_0867	1.955e-27	128.0	2A4PD@1|root,30TAH@2|Bacteria,2GB7S@200795|Chloroflexi,377IM@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS3_k127_7060783_0	84531.JMTZ01000012_gene2935	1.678e-199	633.0	COG1404@1|root,COG1404@2|Bacteria,1REF1@1224|Proteobacteria	1224|Proteobacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_M6,Peptidase_S8
CMS3_k127_7064246_3	316274.Haur_0396	8.694e-20	95.0	COG0583@1|root,COG0583@2|Bacteria,2G910@200795|Chloroflexi,37768@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_7064246_5	316274.Haur_1219	2e-08	62.0	COG0784@1|root,COG0784@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	2|Bacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS3_k127_7064246_1	316274.Haur_0840	6.392e-24	104.0	COG2343@1|root,COG2343@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS3_k127_7064246_6	1348663.KCH_01990	0.0004013	49.0	COG3291@1|root,COG3291@2|Bacteria,2GKA0@201174|Actinobacteria	201174|Actinobacteria	O	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
CMS3_k127_7064246_0	1254432.SCE1572_05510	1.889e-36	156.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7064246_2	329726.AM1_1986	2.229e-23	103.0	COG3695@1|root,COG3695@2|Bacteria,1G82G@1117|Cyanobacteria	1117|Cyanobacteria	L	Methylated dna-protein cysteine methyltransferase	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
CMS3_k127_7064553_1	1499967.BAYZ01000049_gene2756	2.807e-06	51.0	COG0859@1|root,COG2227@1|root,COG2327@1|root,COG4372@1|root,COG0859@2|Bacteria,COG2227@2|Bacteria,COG2327@2|Bacteria,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	wgaD	-	-	ko:K07484,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	DUF3084,Glyco_transf_9,PS_pyruv_trans
CMS3_k127_7064553_0	1304872.JAGC01000009_gene853	3.373e-87	306.0	COG0438@1|root,COG0500@1|root,COG0438@2|Bacteria,COG2226@2|Bacteria,1R9J2@1224|Proteobacteria,42TFT@68525|delta/epsilon subdivisions,2WQDX@28221|Deltaproteobacteria,2MA7M@213115|Desulfovibrionales	28221|Deltaproteobacteria	HM	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Methyltransf_23
CMS3_k127_7066481_0	1123288.SOV_2c12000	1.281e-240	768.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4H1XF@909932|Negativicutes	909932|Negativicutes	P	Copper-exporting ATPase	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_7066481_1	443143.GM18_1317	5.151e-68	245.0	COG2108@1|root,COG2108@2|Bacteria,1MY1Y@1224|Proteobacteria,42MIQ@68525|delta/epsilon subdivisions,2WJD2@28221|Deltaproteobacteria,43TNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS3_k127_707044_0	1499967.BAYZ01000052_gene4665	1.113e-97	349.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
CMS3_k127_7077264_0	326427.Cagg_1038	6.424e-153	509.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi,3759P@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS3_k127_7077264_1	926550.CLDAP_08660	3.036e-151	493.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS3_k127_7077264_2	357808.RoseRS_2964	4.656e-90	299.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2G7MP@200795|Chloroflexi,3760K@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
CMS3_k127_7085050_0	485913.Krac_0518	2.301e-36	148.0	COG0491@1|root,COG0491@2|Bacteria,2G9AW@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_7085222_9	1521187.JPIM01000002_gene3199	2.713e-44	165.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS3_k127_7085222_14	196162.Noca_4719	3.87e-08	59.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria,4DU4K@85009|Propionibacteriales	201174|Actinobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_7085222_11	326427.Cagg_3142	7.905e-25	109.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG3447@1|root,COG3614@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3447@2|Bacteria,COG3614@2|Bacteria,2GBJ0@200795|Chloroflexi,37648@32061|Chloroflexia	32061|Chloroflexia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HATPase_c,HisKA,MASE1,PAS_4,Response_reg
CMS3_k127_7085222_12	926550.CLDAP_33930	7.405e-22	98.0	COG0140@1|root,COG0140@2|Bacteria,2G9QR@200795|Chloroflexi	200795|Chloroflexi	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
CMS3_k127_7085222_10	926550.CLDAP_33920	1.977e-39	149.0	COG0139@1|root,COG0139@2|Bacteria,2G6YA@200795|Chloroflexi	200795|Chloroflexi	E	belongs to the PRA-CH family	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
CMS3_k127_7085222_4	1042156.CXIVA_02780	9.485e-104	345.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,36EBV@31979|Clostridiaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05755	His_biosynth
CMS3_k127_7085222_8	1081640.AGFU01000026_gene2633	1.181e-59	216.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,2K0CJ@204457|Sphingomonadales	204457|Sphingomonadales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_7085222_7	555088.DealDRAFT_1406	6.567e-67	236.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,42KJ6@68298|Syntrophomonadaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_7085222_6	926550.CLDAP_22090	2.288e-74	256.0	COG0131@1|root,COG0131@2|Bacteria,2G6JA@200795|Chloroflexi	200795|Chloroflexi	E	imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS3_k127_7085222_2	926550.CLDAP_22110	1.403e-116	390.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_7085222_1	479434.Sthe_1676	2.409e-122	408.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi,27XKM@189775|Thermomicrobia	189775|Thermomicrobia	C	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS3_k127_7085222_3	926569.ANT_23760	7.136e-115	381.0	COG0040@1|root,COG0040@2|Bacteria,2G6DD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS3_k127_7085222_0	1499967.BAYZ01000171_gene5534	6.474e-126	424.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
CMS3_k127_7085222_13	551789.ATVJ01000001_gene802	4.782e-09	63.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,43XSM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
CMS3_k127_7085222_15	926560.KE387023_gene1426	1.57e-07	63.0	COG1543@1|root,COG1543@2|Bacteria,1WIRT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	hydrolase family 57	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
CMS3_k127_7085222_5	479434.Sthe_1490	1.653e-98	333.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_7086737_3	237368.SCABRO_03969	6.671e-19	91.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	DinB_2,Metallophos_2
CMS3_k127_7086737_2	1321778.HMPREF1982_01457	6.466e-47	177.0	2BZS9@1|root,2ZC3V@2|Bacteria,1V250@1239|Firmicutes,24EXQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_7086737_1	264732.Moth_0912	4.097e-57	228.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_7086737_0	485913.Krac_10670	7.325e-138	475.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
CMS3_k127_7088262_1	485913.Krac_7589	1.295e-14	85.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_7088262_0	316274.Haur_3626	8.464e-16	78.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_7094005_3	797209.ZOD2009_21492	2.112e-25	119.0	COG1402@1|root,arCOG04536@2157|Archaea,2XWZU@28890|Euryarchaeota,23VFZ@183963|Halobacteria	183963|Halobacteria	H	protein, putative amidase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS3_k127_7094005_2	401053.AciPR4_2252	2.545e-76	279.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3XQ@57723|Acidobacteria	57723|Acidobacteria	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_7094005_0	649639.Bcell_1278	2.325e-138	452.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus	91061|Bacilli	E	Acetylornithine deacetylase	yodQ	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_7094005_1	485913.Krac_2138	7.219e-97	331.0	COG2382@1|root,COG2382@2|Bacteria,2G98V@200795|Chloroflexi	2|Bacteria	P	COGs COG2382 Enterochelin esterase	fes	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	DUF3327,Esterase
CMS3_k127_7097488_5	1124780.ANNU01000006_gene2890	3.653e-26	123.0	COG1345@1|root,COG1345@2|Bacteria	2|Bacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02396,ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF1929,F5_F8_type_C,Flagellin_IN,Flagellin_N,Flg_bbr_C,LTD,Laminin_G_3,Peptidase_M6,TMP_2
CMS3_k127_7097488_8	279714.FuraDRAFT_3077	1.181e-11	74.0	COG4932@1|root,COG4932@2|Bacteria,1R944@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7097488_6	926569.ANT_12680	8.034e-26	111.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_7097488_1	316274.Haur_2846	2.186e-139	451.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS3_k127_7097488_3	317936.Nos7107_1153	6.071e-74	259.0	COG1121@1|root,COG1121@2|Bacteria,1G1A6@1117|Cyanobacteria,1HKUZ@1161|Nostocales	1117|Cyanobacteria	P	PFAM ABC transporter	mntA	-	-	ko:K09820,ko:K11603	ko02010,ko02020,map02010,map02020	M00243,M00316	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.1	-	-	ABC_tran
CMS3_k127_7097488_2	316274.Haur_2844	2.038e-111	368.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia	200795|Chloroflexi	P	ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS3_k127_7097488_4	1121272.KB903250_gene2710	8.223e-49	190.0	COG0671@1|root,COG0671@2|Bacteria,2IPT0@201174|Actinobacteria	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS3_k127_7097488_0	926550.CLDAP_04590	1.222e-190	604.0	COG0014@1|root,COG0014@2|Bacteria,2G5TY@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_7097488_7	684949.ATTJ01000001_gene509	2.918e-18	85.0	COG0263@1|root,COG0263@2|Bacteria,1WI1M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS3_k127_7100756_1	326427.Cagg_3185	1.259e-50	200.0	COG2508@1|root,COG2508@2|Bacteria,2G6MB@200795|Chloroflexi,375I0@32061|Chloroflexia	32061|Chloroflexia	K	Purine catabolism regulatory protein-like family	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
CMS3_k127_7100756_0	370438.PTH_2640	1.25e-59	225.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,249I4@186801|Clostridia,260CV@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4
CMS3_k127_7105269_0	926550.CLDAP_29100	1.05e-263	821.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS3_k127_7109819_6	696281.Desru_3291	3.822e-16	81.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,261X6@186807|Peptococcaceae	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_7109819_2	395961.Cyan7425_1902	1.789e-66	237.0	COG1028@1|root,COG1028@2|Bacteria,1G2UM@1117|Cyanobacteria	1117|Cyanobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_7109819_4	1313421.JHBV01000028_gene1857	2.365e-33	150.0	COG1357@1|root,COG1404@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes	976|Bacteroidetes	U	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SBBP
CMS3_k127_7109819_5	926550.CLDAP_06310	2.07e-22	114.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11,SdrD_B
CMS3_k127_7109819_0	251221.35211940	2.066e-127	445.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1G5W7@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS3_k127_7109819_3	762903.Pedsa_2432	1.711e-60	211.0	COG0229@1|root,COG0229@2|Bacteria,4NQEY@976|Bacteroidetes,1ISZN@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptide-methionine (R)-S-oxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS3_k127_7109819_1	550540.Fbal_0533	1.583e-93	317.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,1RQ1W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	IV02_03855	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_7110082_3	1128421.JAGA01000002_gene12	1.255e-64	228.0	COG1131@1|root,COG1131@2|Bacteria,2NPDQ@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7110082_2	926569.ANT_09930	1.315e-104	357.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
CMS3_k127_7110082_0	316274.Haur_3627	1.031e-264	827.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,37630@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_7110082_1	357808.RoseRS_1829	4.052e-165	526.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_7118761_1	443218.AS9A_3448	6.886e-14	79.0	COG0265@1|root,COG0265@2|Bacteria,2IB8S@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_7118761_0	383372.Rcas_3432	2.705e-71	268.0	COG1470@1|root,COG2385@1|root,COG1470@2|Bacteria,COG2385@2|Bacteria,2GBNA@200795|Chloroflexi,37831@32061|Chloroflexia	32061|Chloroflexia	D	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PA14
CMS3_k127_7120302_0	1237149.C900_05784	1.567e-54	192.0	COG0376@1|root,COG0376@2|Bacteria,4NG30@976|Bacteroidetes,47KR2@768503|Cytophagia	976|Bacteroidetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS3_k127_7120302_1	926569.ANT_30930	1.661e-23	104.0	COG3695@1|root,COG3695@2|Bacteria	2|Bacteria	L	enzyme binding	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,YjbR
CMS3_k127_7123111_1	756067.MicvaDRAFT_0615	1.948e-109	374.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HADK@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_7123111_0	306281.AJLK01000081_gene1682	5.522e-273	874.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_7123111_2	118161.KB235922_gene1598	9.043e-65	235.0	COG0500@1|root,COG2226@2|Bacteria,1G2V9@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS3_k127_7123111_3	1174528.JH992893_gene5952	6.508e-32	130.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_7125467_0	926569.ANT_22690	1.697e-212	677.0	COG1132@1|root,COG1132@2|Bacteria,2G7KM@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_7126046_0	926550.CLDAP_11790	8.149e-162	538.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_7126046_1	1128421.JAGA01000003_gene3738	2.563e-53	211.0	COG4745@1|root,COG4745@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7126046_2	1009370.ALO_16986	9.482e-37	143.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4H4FU@909932|Negativicutes	909932|Negativicutes	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_7133437_1	485913.Krac_9189	9.668e-30	119.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi	200795|Chloroflexi	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_7133437_0	493475.GARC_0143	1.217e-196	657.0	COG1404@1|root,COG3227@1|root,COG1404@2|Bacteria,COG3227@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Zinc metalloprotease (Elastase)	prt1	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,PLN_propep,Peptidase_M4,Peptidase_M4_C
CMS3_k127_7133437_2	1536774.H70357_29285	2.621e-06	57.0	COG1647@1|root,COG1647@2|Bacteria,1TVX4@1239|Firmicutes,4HFF2@91061|Bacilli,26QEU@186822|Paenibacillaceae	91061|Bacilli	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
CMS3_k127_7135594_2	5286.M7X0Y5	4.448e-07	60.0	COG2453@1|root,KOG1716@2759|Eukaryota,38DF8@33154|Opisthokonta,3NVXN@4751|Fungi,3UZUR@5204|Basidiomycota,2YCWQ@29000|Pucciniomycotina	4751|Fungi	V	Dual specificity phosphatase, catalytic domain	YVH1	GO:0000003,GO:0000027,GO:0003006,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0008138,GO:0008150,GO:0008152,GO:0009272,GO:0009653,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010494,GO:0010506,GO:0010508,GO:0010638,GO:0010927,GO:0016043,GO:0016239,GO:0016241,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019222,GO:0019538,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0022613,GO:0022618,GO:0023052,GO:0030154,GO:0030435,GO:0030437,GO:0030476,GO:0030684,GO:0030687,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0032991,GO:0033043,GO:0034293,GO:0034622,GO:0035335,GO:0035556,GO:0035770,GO:0036211,GO:0036464,GO:0042244,GO:0042254,GO:0042255,GO:0042273,GO:0042546,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043933,GO:0043934,GO:0043935,GO:0044085,GO:0044087,GO:0044088,GO:0044089,GO:0044090,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045229,GO:0048468,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051321,GO:0051704,GO:0051716,GO:0065003,GO:0065007,GO:0070590,GO:0070591,GO:0070726,GO:0070925,GO:0071554,GO:0071555,GO:0071704,GO:0071826,GO:0071840,GO:0071852,GO:0071940,GO:0140096,GO:1901564,GO:1902115,GO:1902117,GO:1903046,GO:1990904,GO:2000785,GO:2000786	3.1.3.16,3.1.3.48	ko:K14819	-	-	-	-	ko00000,ko01000,ko01009,ko03009	-	-	-	DSPc
CMS3_k127_7135594_0	1502724.FF80_03455	2.091e-63	223.0	COG3896@1|root,COG3896@2|Bacteria,1NX1Z@1224|Proteobacteria,2U3CG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
CMS3_k127_7135594_1	1123399.AQVE01000002_gene2329	1.829e-31	134.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,He_PIG,OmpA,OmpA_membrane,fn3
CMS3_k127_7142451_2	1071400.LBUCD034_1106	1.072e-20	94.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS3_k127_7142451_1	351160.LRC209	5.367e-37	150.0	COG1668@1|root,arCOG01462@2157|Archaea	2157|Archaea	CP	ABC-type Na efflux pump, permease	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS3_k127_7142451_0	304371.MCP_1847	4.113e-102	342.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT7Q@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7143064_3	867845.KI911784_gene362	3.464e-92	334.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH,fn3
CMS3_k127_7143064_6	1219077.VAZ01S_062_00100	1.015e-16	95.0	COG3227@1|root,COG3591@1|root,COG3227@2|Bacteria,COG3591@2|Bacteria,1QXPY@1224|Proteobacteria,1T3FP@1236|Gammaproteobacteria,1XVQJ@135623|Vibrionales	135623|Vibrionales	M	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FTP,Peptidase_M36
CMS3_k127_7143064_5	82654.Pse7367_1999	1.446e-47	184.0	COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria,1H8N9@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_7143064_2	926569.ANT_29690	1.272e-108	361.0	COG3842@1|root,COG3842@2|Bacteria,2G5P8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS3_k127_7143064_0	266117.Rxyl_1174	1.682e-161	526.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS3_k127_7143064_1	266117.Rxyl_1175	1.571e-121	399.0	COG1840@1|root,COG1840@2|Bacteria,2HRRI@201174|Actinobacteria,4CTU6@84995|Rubrobacteria	84995|Rubrobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
CMS3_k127_7143064_4	357808.RoseRS_3079	1.252e-53	192.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,37577@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aspartate glutamate uridylate kinase	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
CMS3_k127_714467_0	670487.Ocepr_1261	3.062e-45	171.0	COG1970@1|root,COG1970@2|Bacteria,1WKJU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS3_k127_7148155_3	67373.JOBF01000012_gene3983	0.0006192	51.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_7148155_1	749414.SBI_02215	1.584e-23	107.0	2BTC8@1|root,32NI0@2|Bacteria,2IPGR@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7148155_2	644282.Deba_2487	2.999e-20	98.0	COG2020@1|root,COG2020@2|Bacteria,1PK64@1224|Proteobacteria,432NT@68525|delta/epsilon subdivisions,2WX82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7148155_0	543632.JOJL01000017_gene9935	2.268e-27	114.0	COG5587@1|root,COG5587@2|Bacteria	2|Bacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
CMS3_k127_7152838_2	552811.Dehly_0557	3e-28	131.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_7152838_1	1449076.JOOE01000004_gene231	2.433e-61	218.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria,2K5XG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CMS3_k127_7152838_0	644076.SCH4B_3711	3.716e-65	226.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,2UC68@28211|Alphaproteobacteria,4NDIY@97050|Ruegeria	28211|Alphaproteobacteria	S	Phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CMS3_k127_7153647_0	665571.STHERM_c15400	4.491e-29	133.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,LVIVD
CMS3_k127_7154201_2	309801.trd_1352	1.809e-20	102.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi,27YZX@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
CMS3_k127_7154201_0	326427.Cagg_3160	2.954e-50	189.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi,376U0@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
CMS3_k127_7154201_1	1379698.RBG1_1C00001G1781	2.821e-33	139.0	COG0382@1|root,COG0382@2|Bacteria,2NQZV@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39,2.5.1.42	ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00117	R04520,R05000,R05615	RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_7155504_4	1341151.ASZU01000003_gene2288	3.02e-15	76.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,27AV7@186824|Thermoactinomycetaceae	91061|Bacilli	S	Beta-lactamase superfamily domain	bCE_4747	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS3_k127_7155504_3	867845.KI911784_gene9	5.158e-42	165.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi,375JV@32061|Chloroflexia	32061|Chloroflexia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
CMS3_k127_7155504_1	926569.ANT_09740	3.986e-108	356.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
CMS3_k127_7155504_5	37659.JNLN01000001_gene165	1.394e-14	76.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,36MK5@31979|Clostridiaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
CMS3_k127_7155504_2	926569.ANT_09760	4.183e-80	280.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS3_k127_7155504_0	1382356.JQMP01000003_gene2026	2.749e-115	383.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi,27XPN@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS3_k127_7158642_1	926550.CLDAP_04770	1.78e-154	495.0	COG0119@1|root,COG0119@2|Bacteria,2G5N1@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K01655	ko00300,ko00620,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00620,map01100,map01120,map01130,map01210,map01230	M00030,M00433	R00271	RC00004,RC00067,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_7158642_2	1128421.JAGA01000001_gene2375	4.663e-154	497.0	COG0065@1|root,COG0065@2|Bacteria,2NP32@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	hacA	-	4.2.1.114,4.2.1.33,4.2.1.35	ko:K01703,ko:K16792	ko00290,ko00300,ko00660,ko00680,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00680,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00432,M00433,M00535,M00608	R03444,R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R09720,R10170,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS3_k127_7158642_15	765420.OSCT_2490	7.603e-54	193.0	COG0066@1|root,COG0066@2|Bacteria,2G6PB@200795|Chloroflexi,375GS@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.114	ko:K16793	ko00300,ko00680,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00680,map01100,map01120,map01130,map01210,map01230	M00433,M00608	R03444,R04371,R09720,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS3_k127_7158642_5	95619.PM1_0205215	2.216e-117	387.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,1T1N6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CE	Isocitrate isopropylmalate dehydrogenase	dlpA	-	1.1.1.85,1.1.1.87	ko:K00052,ko:K05824	ko00290,ko00300,ko00660,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R00994,R01934,R01936,R04426,R04862,R10052	RC00084,RC00114,RC00417,RC00626,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh,RraA-like
CMS3_k127_7158642_18	926550.CLDAP_07270	7.761e-35	142.0	2DT85@1|root,33J4K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7158642_17	926550.CLDAP_07260	1.894e-35	140.0	2E3MN@1|root,32YJW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7158642_0	649638.Trad_2223	4.132e-253	790.0	COG0166@1|root,COG0166@2|Bacteria,1WIGN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS3_k127_7158642_23	935567.JAES01000006_gene409	2.112e-06	60.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,1RYY4@1236|Gammaproteobacteria,1X5PE@135614|Xanthomonadales	135614|Xanthomonadales	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
CMS3_k127_7158642_11	760568.Desku_1386	2.129e-73	263.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,261CQ@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7158642_6	937777.Deipe_0860	3.795e-103	351.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_7158642_19	869210.Marky_0586	2.676e-34	138.0	COG1765@1|root,COG1765@2|Bacteria,1WMSR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_7158642_14	997346.HMPREF9374_3151	1.403e-54	220.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27B9F@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_7158642_10	926560.KE387023_gene3595	4.304e-82	308.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS3_k127_7158642_22	663278.Ethha_1429	1.048e-09	71.0	COG4193@1|root,COG4193@2|Bacteria	2|Bacteria	G	domain, Protein	entD	-	3.2.1.96,3.5.1.28	ko:K13714	-	-	-	-	ko00000,ko01000	-	GH73	-	Cu_amine_oxidN1,Glucosaminidase,PG_binding_1,SH3_3
CMS3_k127_7158642_21	1033743.CAES01000085_gene2957	6.296e-17	94.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_17_28,CBM_2,CBM_3,CBM_6,Cellulase,F5_F8_type_C,Glyco_hydro_26,Glyco_hydro_8
CMS3_k127_7158642_4	1400524.KL370779_gene1323	5.293e-124	407.0	COG4175@1|root,COG4175@2|Bacteria,1MU86@1224|Proteobacteria,2TS8Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG4175 ABC-type proline glycine betaine transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_7158642_3	67332.FM21_25395	5.745e-125	425.0	COG4176@1|root,COG4176@2|Bacteria,2GKRF@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type proline glycine betaine transport system permease component	proW	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
CMS3_k127_7158642_13	68223.JNZY01000012_gene1240	1.082e-61	225.0	COG2113@1|root,COG2113@2|Bacteria,2GP39@201174|Actinobacteria	201174|Actinobacteria	E	glycine betaine transport	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
CMS3_k127_7158642_20	1385935.N836_32200	2.868e-27	131.0	COG2319@1|root,COG3629@1|root,COG2319@2|Bacteria,COG3629@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NACHT,NB-ARC,Pentapeptide,WD40
CMS3_k127_7158642_7	1121377.KB906402_gene3232	2.868e-93	345.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
CMS3_k127_7158642_16	316274.Haur_2801	4.342e-39	162.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_7158642_12	1128421.JAGA01000002_gene1281	5.488e-73	261.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_7158642_9	102232.GLO73106DRAFT_00034110	2.187e-88	302.0	COG4275@1|root,COG4275@2|Bacteria	2|Bacteria	S	Chromate resistance exported protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
CMS3_k127_7158642_8	351348.Maqu_3191	2.157e-91	308.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,1RPNP@1236|Gammaproteobacteria,469DA@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CMS3_k127_7164612_0	316274.Haur_2040	1.458e-109	391.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2G71Q@200795|Chloroflexi,376GZ@32061|Chloroflexia	2|Bacteria	NU	SMART Tetratricopeptide domain protein	-	-	2.7.11.1,3.6.4.12	ko:K03654,ko:K11935,ko:K14949,ko:K21007	ko02025,ko02026,ko03018,ko05152,map02025,map02026,map03018,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03400	-	-	-	Pkinase,PknG_TPR,PknG_rubred,TPR_15,TPR_16,TPR_19
CMS3_k127_7164612_1	1523503.JPMY01000006_gene2258	3.177e-26	127.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
CMS3_k127_7164612_2	383372.Rcas_2574	3.502e-20	105.0	COG1572@1|root,COG3386@1|root,COG1572@2|Bacteria,COG3386@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
CMS3_k127_7166662_5	102129.Lepto7375DRAFT_1723	1.951e-43	166.0	2BQFG@1|root,32JAW@2|Bacteria,1GF3H@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7166662_10	76114.ebB145	3.21e-12	74.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP-7	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_7166662_2	102129.Lepto7375DRAFT_8116	1.853e-151	487.0	COG1960@1|root,COG1960@2|Bacteria,1G4K8@1117|Cyanobacteria,1HE4R@1150|Oscillatoriales	1117|Cyanobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7166662_3	99598.Cal7507_5045	2.085e-135	449.0	COG0644@1|root,COG0644@2|Bacteria,1GJW2@1117|Cyanobacteria,1HSQG@1161|Nostocales	1117|Cyanobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CMS3_k127_7166662_0	76114.ebA4326	2.704e-185	593.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KW0H@206389|Rhodocyclales	206389|Rhodocyclales	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Hexapep,PP-binding
CMS3_k127_7166662_1	76114.ebA4323	3.042e-177	588.0	COG1696@1|root,COG1696@2|Bacteria	2|Bacteria	M	negative regulation of protein lipidation	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
CMS3_k127_7166662_4	926569.ANT_16410	1.255e-53	209.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
CMS3_k127_7166662_9	926569.ANT_16420	1.896e-17	92.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS3_k127_7166662_6	1196324.A374_18019	7.585e-40	162.0	28MVU@1|root,2ZB3B@2|Bacteria,1V0YH@1239|Firmicutes,4HBRC@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_7166662_7	765420.OSCT_3163	5.262e-29	123.0	COG1896@1|root,COG1896@2|Bacteria,2G72G@200795|Chloroflexi,3778D@32061|Chloroflexia	32061|Chloroflexia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
CMS3_k127_7166662_8	1121015.N789_12435	2.429e-22	113.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1X4SZ@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
CMS3_k127_7170975_0	383372.Rcas_2386	7.036e-147	478.0	COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi	200795|Chloroflexi	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS3_k127_7170975_1	720555.BATR1942_00855	7.186e-70	248.0	COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,1ZEJM@1386|Bacillus	91061|Bacilli	S	homoserine kinase type II (protein kinase fold)	yerI	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_7172812_3	1463917.JODC01000003_gene5392	0.0008692	46.0	COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
CMS3_k127_7172812_0	204669.Acid345_1066	4.178e-100	353.0	COG1404@1|root,COG1409@1|root,COG3055@1|root,COG3291@1|root,COG3386@1|root,COG1404@2|Bacteria,COG1409@2|Bacteria,COG3055@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria,2JMMV@204432|Acidobacteriia	204432|Acidobacteriia	GO	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	ASH
CMS3_k127_7172812_2	640511.BC1002_6450	1.505e-29	120.0	2AGAH@1|root,316G1@2|Bacteria,1N2FZ@1224|Proteobacteria,2WCY6@28216|Betaproteobacteria,1K8RB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS3_k127_7172812_1	196367.JNFG01000034_gene7526	2.113e-72	267.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Pkinase,SAM_1
CMS3_k127_7173658_0	471853.Bcav_3580	2.139e-196	628.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_7174252_4	1137271.AZUM01000002_gene2350	7.683e-05	53.0	2E35R@1|root,32Y5N@2|Bacteria,2H8P1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7174252_3	928724.SacglDRAFT_03498	5.1e-05	54.0	2E35R@1|root,32Y5N@2|Bacteria,2H8P1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7174252_2	98439.AJLL01000098_gene1988	3.914e-12	75.0	2E16S@1|root,32WMI@2|Bacteria,1G8JJ@1117|Cyanobacteria,1JKYG@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7174252_0	290317.Cpha266_0841	1.68e-231	737.0	COG1132@1|root,COG1132@2|Bacteria,1FD6W@1090|Chlorobi	1090|Chlorobi	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_7174252_1	290317.Cpha266_0842	9.665e-178	569.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_7178754_0	1499967.BAYZ01000009_gene5353	4.735e-195	641.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
CMS3_k127_7178754_1	402777.KB235903_gene1565	5.076e-180	577.0	COG2114@1|root,COG2114@2|Bacteria,1G335@1117|Cyanobacteria,1H8VG@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_7178754_3	765420.OSCT_2978	1.18e-17	84.0	28VCT@1|root,2ZHFH@2|Bacteria,2GB88@200795|Chloroflexi,377J8@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7178754_2	197221.22294686	1.135e-82	282.0	COG0455@1|root,COG0455@2|Bacteria,1G1EJ@1117|Cyanobacteria	1117|Cyanobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7178754_4	1123504.JQKD01000018_gene2026	7.341e-17	93.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria,4AC3E@80864|Comamonadaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, crp family	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
CMS3_k127_7178754_6	419947.MRA_3280	7.72e-09	68.0	COG0477@1|root,COG0664@1|root,COG1752@1|root,COG0477@2|Bacteria,COG0664@2|Bacteria,COG1752@2|Bacteria,2GMEJ@201174|Actinobacteria,235AW@1762|Mycobacteriaceae	201174|Actinobacteria	EGPT	Major facilitator superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	MFS_1,MFS_3,Patatin,Sugar_tr,cNMP_binding
CMS3_k127_7178754_5	1041930.Mtc_0014	2.009e-12	79.0	COG2339@1|root,arCOG02985@2157|Archaea,2Y73S@28890|Euryarchaeota,2NB99@224756|Methanomicrobia	224756|Methanomicrobia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
CMS3_k127_7189680_0	1167006.UWK_00584	5.379e-178	569.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CMS3_k127_7189680_1	926569.ANT_02860	8.551e-76	269.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS3_k127_7192449_3	1123504.JQKD01000007_gene3334	1.966e-87	306.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2VMSN@28216|Betaproteobacteria,4ABYN@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
CMS3_k127_7192449_2	1121468.AUBR01000028_gene1527	1.322e-131	430.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42I2K@68295|Thermoanaerobacterales	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7192449_0	309799.DICTH_1154	1.937e-193	613.0	COG1350@1|root,COG1350@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_7192449_1	335543.Sfum_0387	2.4e-174	566.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WKYE@28221|Deltaproteobacteria,2MQ87@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-2	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
CMS3_k127_7192449_6	269799.Gmet_0949	4.992e-31	130.0	COG1014@1|root,COG1014@2|Bacteria,1N2W3@1224|Proteobacteria,42THX@68525|delta/epsilon subdivisions,2WQ6P@28221|Deltaproteobacteria,43V53@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	iorB-2	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
CMS3_k127_7192449_4	706587.Desti_1814	1.537e-63	229.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42RE0@68525|delta/epsilon subdivisions,2WNYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein	pcmR	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_7192449_5	865861.AZSU01000001_gene549	1.991e-46	173.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,36IEF@31979|Clostridiaceae	186801|Clostridia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_7195165_0	251221.35210810	7.017e-25	106.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7195165_1	324602.Caur_0300	4.474e-13	72.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7195165_2	794903.OPIT5_15480	8.759e-08	64.0	COG3420@1|root,COG3420@2|Bacteria,46Y1Y@74201|Verrucomicrobia,3K8T9@414999|Opitutae	414999|Opitutae	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_7201274_2	368407.Memar_2468	7.885e-58	213.0	COG2208@1|root,arCOG06893@2157|Archaea,2Y35A@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	5TM-5TMR_LYT,SpoIIE
CMS3_k127_7201274_1	1501230.ET33_20830	2.459e-60	216.0	COG1713@1|root,COG1713@2|Bacteria,1V44H@1239|Firmicutes,4HH8H@91061|Bacilli,26VP4@186822|Paenibacillaceae	91061|Bacilli	H	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_7201274_3	102129.Lepto7375DRAFT_8055	1.613e-56	207.0	28XBK@1|root,2ZJ9G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7201274_0	383372.Rcas_1877	5.115e-63	226.0	COG0639@1|root,COG0639@2|Bacteria,2G71P@200795|Chloroflexi,375UU@32061|Chloroflexia	32061|Chloroflexia	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_7204780_0	1242864.D187_001830	4.188e-201	670.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS3_k127_7204780_2	1121875.KB907548_gene1637	2.314e-27	116.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_7204780_1	1168034.FH5T_19015	8.038e-116	389.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7204780_3	926569.ANT_12610	1.205e-24	105.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
CMS3_k127_7204780_4	926569.ANT_12600	8.707e-17	82.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
CMS3_k127_7205683_6	1347086.CCBA010000025_gene3143	1.837e-13	73.0	COG3570@1|root,COG3570@2|Bacteria,1V5G9@1239|Firmicutes,4HH9E@91061|Bacilli,1ZFTN@1386|Bacillus	91061|Bacilli	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
CMS3_k127_7205683_5	1492738.FEM21_17990	6.204e-27	116.0	COG2318@1|root,COG2318@2|Bacteria,4NSEY@976|Bacteroidetes,1I2YX@117743|Flavobacteriia,2NWA5@237|Flavobacterium	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_7205683_4	1121920.AUAU01000006_gene267	3.698e-32	128.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_7205683_1	1265505.ATUG01000002_gene1702	4.165e-101	342.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42UHV@68525|delta/epsilon subdivisions,2WQCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
CMS3_k127_7205683_0	926560.KE387023_gene2684	6.313e-176	574.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,GerE,Trans_reg_C
CMS3_k127_7205683_2	1458357.BG58_38300	3.942e-74	259.0	COG0500@1|root,COG2226@2|Bacteria,1NNRW@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS3_k127_7205683_3	349521.HCH_04893	1.542e-34	139.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1XR4N@135619|Oceanospirillales	135619|Oceanospirillales	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_7206925_5	926569.ANT_16180	4.743e-31	126.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS3_k127_7206925_2	479434.Sthe_0311	3.569e-51	190.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_7206925_0	926550.CLDAP_10480	5.034e-161	518.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	rfbH	-	1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_7206925_6	1408422.JHYF01000017_gene1849	1.219e-05	57.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	1239|Firmicutes	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_7206925_4	926569.ANT_08950	5.815e-34	151.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
CMS3_k127_7206925_1	335543.Sfum_2288	2.23e-117	392.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_7206925_3	477641.MODMU_2510	2.402e-38	155.0	COG1864@1|root,COG1864@2|Bacteria,2IGAH@201174|Actinobacteria	201174|Actinobacteria	L	DNA RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS
CMS3_k127_7208145_1	649831.L083_6838	8.438e-55	198.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4DCKB@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
CMS3_k127_7208145_0	420662.Mpe_A0106	4.603e-70	256.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria	1224|Proteobacteria	S	Von willebrand factor, type a	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_7209431_2	1150600.ADIARSV_2338	2.862e-33	151.0	COG1361@1|root,COG1361@2|Bacteria,4NT9E@976|Bacteroidetes	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_7209431_4	323261.Noc_1876	2.267e-07	66.0	COG1388@1|root,COG3115@1|root,COG1388@2|Bacteria,COG3115@2|Bacteria,1QZ0G@1224|Proteobacteria,1SFRU@1236|Gammaproteobacteria,1WZJB@135613|Chromatiales	1236|Gammaproteobacteria	D	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_7209431_0	1150600.ADIARSV_2338	3.819e-63	251.0	COG1361@1|root,COG1361@2|Bacteria,4NT9E@976|Bacteroidetes	976|Bacteroidetes	M	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_7209431_3	323261.Noc_1876	4.997e-12	82.0	COG1388@1|root,COG3115@1|root,COG1388@2|Bacteria,COG3115@2|Bacteria,1QZ0G@1224|Proteobacteria,1SFRU@1236|Gammaproteobacteria,1WZJB@135613|Chromatiales	1236|Gammaproteobacteria	D	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157
CMS3_k127_7209431_1	889378.Spiaf_1100	1.824e-43	173.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
CMS3_k127_7212555_0	479434.Sthe_2647	5.386e-214	683.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,27XX7@189775|Thermomicrobia	189775|Thermomicrobia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
CMS3_k127_7212555_2	926569.ANT_02580	2.262e-91	310.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_7212555_11	926569.ANT_02670	1.824e-12	73.0	COG0347@1|root,COG0347@2|Bacteria,2G9NA@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7212555_7	926550.CLDAP_21740	1.248e-61	224.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS3_k127_7212555_1	243230.DR_0599	5.959e-98	328.0	COG2746@1|root,COG2746@2|Bacteria	2|Bacteria	V	aminoglycoside 3-N-acetyltransferase activity	aacC	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
CMS3_k127_7212555_8	383372.Rcas_2980	2.29e-60	216.0	COG0120@1|root,COG0120@2|Bacteria,2G6NN@200795|Chloroflexi,377B7@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS3_k127_7212555_13	926550.CLDAP_22520	0.0001055	54.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1,3.4.21.107,3.5.1.28	ko:K01448,ko:K04771,ko:K08884	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
CMS3_k127_7212555_5	251229.Chro_4930	4.115e-65	231.0	COG1434@1|root,COG1434@2|Bacteria,1G1QC@1117|Cyanobacteria,3VHWT@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS3_k127_7212555_10	684949.ATTJ01000001_gene2175	1.066e-35	150.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_7212555_3	926561.KB900622_gene464	1.655e-88	301.0	COG0524@1|root,COG0524@2|Bacteria,1V0D5@1239|Firmicutes,249XQ@186801|Clostridia	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_7212555_9	926569.ANT_30860	4.924e-40	156.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_7212555_6	313612.L8106_01587	1.067e-63	228.0	COG0566@1|root,COG0566@2|Bacteria,1G05W@1117|Cyanobacteria,1HAR0@1150|Oscillatoriales	1117|Cyanobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylas_C,SpoU_methylase
CMS3_k127_7212555_12	743721.Psesu_2129	1.753e-11	70.0	COG2018@1|root,COG2018@2|Bacteria,1RIQC@1224|Proteobacteria,1S65Z@1236|Gammaproteobacteria,1X7KJ@135614|Xanthomonadales	135614|Xanthomonadales	S	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
CMS3_k127_7212555_4	383372.Rcas_2148	3.808e-69	250.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
CMS3_k127_7213362_2	56107.Cylst_0426	2.187e-23	108.0	COG0823@1|root,COG5276@1|root,COG0823@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
CMS3_k127_7213362_1	983545.Glaag_1670	4.175e-32	127.0	COG2944@1|root,COG2944@2|Bacteria,1N0M9@1224|Proteobacteria,1T0CA@1236|Gammaproteobacteria,46D0N@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	MqsA_antitoxin
CMS3_k127_7213362_0	555779.Dthio_PD1768	5.288e-39	149.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,42V08@68525|delta/epsilon subdivisions,2X5CG@28221|Deltaproteobacteria,2MGPE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7213362_4	926550.CLDAP_21830	1.274e-05	51.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7219006_0	926569.ANT_12430	9.481e-157	507.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi	200795|Chloroflexi	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS3_k127_7219063_1	926550.CLDAP_20060	2.754e-104	364.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS3_k127_7219063_0	309801.trd_1791	1.077e-139	457.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_7219063_2	926569.ANT_31060	3.274e-33	137.0	COG1011@1|root,COG1011@2|Bacteria,2G787@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_7219063_3	485913.Krac_9502	1.703e-29	125.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	fadB5	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_7243905_1	63737.Npun_F4523	3.354e-22	97.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,1HJXK@1161|Nostocales	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
CMS3_k127_7243905_2	383372.Rcas_2829	1.623e-11	77.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2,DUF4157,DUF5011,PG_binding_1,Peptidase_C70,SLT,YkuD
CMS3_k127_7243905_0	1128421.JAGA01000003_gene3536	1.958e-92	316.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_7244625_0	479434.Sthe_0598	1.342e-134	473.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS3_k127_7244625_2	1120970.AUBZ01000001_gene3857	6.242e-93	310.0	COG3506@1|root,COG3506@2|Bacteria,1R7MF@1224|Proteobacteria,1S2RG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
CMS3_k127_7244625_3	1267535.KB906767_gene1219	5.453e-61	224.0	28NY3@1|root,2ZBVC@2|Bacteria,3Y8CE@57723|Acidobacteria,2JNAC@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7244625_1	649638.Trad_2919	3.477e-100	341.0	COG2124@1|root,COG2124@2|Bacteria,1WIX6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS3_k127_7244625_4	504728.K649_11185	2.794e-24	109.0	294HY@1|root,2ZRXK@2|Bacteria,1WK25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
CMS3_k127_7251502_0	1173028.ANKO01000086_gene4	5.283e-52	192.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_7251502_1	926554.KI912674_gene2521	3.467e-18	93.0	COG0451@1|root,COG0451@2|Bacteria,1WN3C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_7258708_1	926569.ANT_24700	4.389e-123	404.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS3_k127_7258708_2	1121936.AUHI01000004_gene1342	8.8e-06	57.0	2DBYB@1|root,2ZBUC@2|Bacteria,1V738@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7258708_0	717231.Flexsi_0623	7.612e-138	451.0	COG0104@1|root,COG0104@2|Bacteria,2GEUU@200930|Deferribacteres	200930|Deferribacteres	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS3_k127_7261345_1	1449976.KALB_4357	7.835e-15	85.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2I12T@201174|Actinobacteria,4DX7Y@85010|Pseudonocardiales	201174|Actinobacteria	L	UvrD/REP helicase N-terminal domain	pcrA	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_7261345_0	1121946.AUAX01000002_gene324	8.131e-70	245.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	ko:K18399	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_7261345_2	392499.Swit_2307	2.571e-11	67.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,2K07N@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_7262350_3	1033806.HTIA_1223	4.996e-10	72.0	arCOG14663@1|root,arCOG14663@2157|Archaea,2Y1E5@28890|Euryarchaeota	28890|Euryarchaeota	S	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
CMS3_k127_7262350_2	765420.OSCT_1559	2.632e-20	98.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7262350_0	357808.RoseRS_2790	7.721e-56	201.0	COG0500@1|root,COG2226@2|Bacteria,2G72C@200795|Chloroflexi,3761H@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_7262350_5	500153.JOEK01000009_gene5085	1.185e-05	57.0	2EHE6@1|root,33B62@2|Bacteria,2I8VI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7262350_4	1122612.AUBA01000013_gene293	5.478e-10	69.0	28J5H@1|root,2Z91B@2|Bacteria,1P7D2@1224|Proteobacteria,2U3J1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7262350_1	926550.CLDAP_39250	3.427e-54	202.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_7263429_9	357808.RoseRS_3277	2.79e-57	208.0	COG4585@1|root,COG4585@2|Bacteria,2G8N5@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_7263429_10	357808.RoseRS_3278	2.5e-49	184.0	COG2197@1|root,COG2197@2|Bacteria,2G8NX@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_7263429_3	1401064.HMPREF2129_07000	3.444e-116	383.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,22JV6@1653|Corynebacteriaceae	201174|Actinobacteria	G	fructose-1,6-bisphosphatase	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
CMS3_k127_7263429_1	1183438.GKIL_0669	1.332e-157	509.0	COG1850@1|root,COG1850@2|Bacteria,1G05Z@1117|Cyanobacteria	1117|Cyanobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
CMS3_k127_7263429_2	765420.OSCT_2525	1.36e-138	447.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	prk	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
CMS3_k127_7263429_0	478741.JAFS01000002_gene71	1.878e-248	784.0	COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,37G0P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS3_k127_7263429_5	478741.JAFS01000001_gene1200	1.285e-86	291.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,37GED@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_7263429_13	309801.trd_0152	5.856e-08	57.0	2EQM1@1|root,33I6Z@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS3_k127_7263429_12	1284352.AOIG01000017_gene4494	3.476e-24	113.0	COG4627@1|root,COG4627@2|Bacteria,1UMZS@1239|Firmicutes,4IUPP@91061|Bacilli,277PK@186822|Paenibacillaceae	91061|Bacilli	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS3_k127_7263429_11	272134.KB731325_gene708	1.374e-39	158.0	COG1670@1|root,COG1670@2|Bacteria,1GQTY@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_7263429_4	316274.Haur_0779	2.159e-102	344.0	2EC8P@1|root,33674@2|Bacteria,2G9A5@200795|Chloroflexi,377GT@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7263429_6	316274.Haur_0780	1.695e-81	279.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_7263429_7	497964.CfE428DRAFT_6382	1.85e-69	249.0	COG3509@1|root,COG3509@2|Bacteria,46VHF@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_7263429_14	317936.Nos7107_5168	1.6e-07	61.0	2A07X@1|root,30NB4@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
CMS3_k127_7263429_15	745411.B3C1_03185	1.865e-07	59.0	2A07X@1|root,30NB4@2|Bacteria,1N1WT@1224|Proteobacteria,1S9GH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
CMS3_k127_7263429_8	306281.AJLK01000102_gene3405	2.607e-67	233.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7264801_0	373903.Hore_06870	2.181e-25	109.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,3WC2X@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
CMS3_k127_7264801_1	234267.Acid_6349	1.405e-19	102.0	COG4219@1|root,COG4219@2|Bacteria,3Y5D9@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7265881_1	903818.KI912268_gene1657	8.995e-94	317.0	COG2069@1|root,COG2069@2|Bacteria	2|Bacteria	C	one-carbon metabolic process	acsD	-	1.2.7.4,2.1.1.245	ko:K00194,ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R07157,R08034,R09096,R10219,R10243	RC00004,RC00113,RC00250,RC02800,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
CMS3_k127_7265881_0	555779.Dthio_PD3225	1.63e-117	392.0	COG1456@1|root,COG1456@2|Bacteria,1R4RE@1224|Proteobacteria,42M89@68525|delta/epsilon subdivisions,2WJVQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
CMS3_k127_7265881_2	933262.AXAM01000033_gene1642	7.344e-12	71.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MI52@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS3_k127_7268681_3	1128421.JAGA01000002_gene101	4.785e-37	150.0	COG0584@1|root,COG0584@2|Bacteria,2NPNS@2323|unclassified Bacteria	2|Bacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_7268681_2	1121091.AUMP01000005_gene1650	4.091e-47	181.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,4HG91@91061|Bacilli	91061|Bacilli	G	aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS3_k127_7268681_0	926569.ANT_20830	5.744e-63	229.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS3_k127_7268681_1	1255043.TVNIR_0418	2.147e-48	179.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1WWQE@135613|Chromatiales	135613|Chromatiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS3_k127_7272877_1	288000.BBta_2683	1.431e-66	235.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,3JRQ8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	1.14.13.40,1.6.99.1	ko:K00354,ko:K09461	ko00627,ko01120,map00627,map01120	-	R00282,R03998,R03999	RC00001,RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
CMS3_k127_7272877_0	485913.Krac_2147	5.368e-110	361.0	COG1024@1|root,COG1024@2|Bacteria,2G6G6@200795|Chloroflexi	2|Bacteria	I	PFAM Enoyl-CoA hydratase isomerase	MA20_38145	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_7286317_2	1449346.JQMO01000002_gene898	1.025e-14	85.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,2M5N2@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_7286317_1	926569.ANT_17840	6.286e-26	111.0	COG0375@1|root,COG0375@2|Bacteria,2G7H5@200795|Chloroflexi	200795|Chloroflexi	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
CMS3_k127_7286317_0	211114.JOEF01000008_gene1172	9.009e-54	194.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria,4DYVA@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
CMS3_k127_7292141_1	324602.Caur_2628	5.911e-87	293.0	COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS3_k127_7292141_3	485913.Krac_5508	3.526e-15	84.0	COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi	2|Bacteria	S	SPTR D1C1B9 DinB family protein	dinB	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
CMS3_k127_7292141_2	485913.Krac_2635	2.006e-26	117.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS3_k127_7292141_0	485913.Krac_2635	4.602e-154	516.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS3_k127_7294508_2	1122218.KB893654_gene2217	4.038e-05	53.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase M48	MA20_29180	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16,TPR_19
CMS3_k127_7294508_0	1009370.ALO_18747	8.297e-119	397.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4H40R@909932|Negativicutes	909932|Negativicutes	GM	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Wzt_C
CMS3_k127_7294508_1	1121438.JNJA01000004_gene793	1.24e-74	264.0	COG0438@1|root,COG2227@1|root,COG0438@2|Bacteria,COG2227@2|Bacteria,1R9J2@1224|Proteobacteria,42TFT@68525|delta/epsilon subdivisions,2WQDX@28221|Deltaproteobacteria,2MA7M@213115|Desulfovibrionales	28221|Deltaproteobacteria	HM	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Methyltransf_23
CMS3_k127_7294712_0	574087.Acear_1870	1.572e-153	502.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WBGE@53433|Halanaerobiales	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS3_k127_7297240_3	1415166.NONO_c58870	5.633e-06	53.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,Pkinase
CMS3_k127_7297240_0	1169152.AXVD01000023_gene3256	1.236e-55	207.0	COG2021@1|root,COG2021@2|Bacteria,2HIEG@201174|Actinobacteria,4G3VG@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_7297240_2	1120950.KB892831_gene5057	3.111e-22	102.0	COG1936@1|root,COG1936@2|Bacteria,2GTBV@201174|Actinobacteria,4DVGP@85009|Propionibacteriales	201174|Actinobacteria	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7297240_1	997346.HMPREF9374_2085	1.224e-40	155.0	COG0457@1|root,COG0457@2|Bacteria,1V3U6@1239|Firmicutes,4HFWW@91061|Bacilli,27CYZ@186824|Thermoactinomycetaceae	91061|Bacilli	S	Tetratrico peptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_5,TPR_6,TPR_8
CMS3_k127_7300983_2	926550.CLDAP_34250	3.555e-65	234.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
CMS3_k127_7300983_5	37659.JNLN01000001_gene812	0.0002096	46.0	COG0526@1|root,COG0526@2|Bacteria,1UEYZ@1239|Firmicutes,24S3K@186801|Clostridia	186801|Clostridia	CO	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_7300983_4	1121406.JAEX01000009_gene2668	1.511e-30	125.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42VTR@68525|delta/epsilon subdivisions,2X5PP@28221|Deltaproteobacteria,2MGU1@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS3_k127_7300983_0	926550.CLDAP_02910	5.173e-149	484.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi	200795|Chloroflexi	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS3_k127_7300983_3	926550.CLDAP_29190	1.059e-43	178.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
CMS3_k127_7300983_1	926550.CLDAP_02140	9.217e-71	250.0	COG1682@1|root,COG1682@2|Bacteria,2G6QU@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_7314745_4	324602.Caur_3066	1.45e-77	267.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,375BD@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_7314745_2	1379698.RBG1_1C00001G0857	1.716e-100	346.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7314745_5	309801.trd_0468	1.456e-63	227.0	COG0437@1|root,COG0437@2|Bacteria,2G6C1@200795|Chloroflexi,27XMT@189775|Thermomicrobia	189775|Thermomicrobia	C	4Fe-4S binding domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
CMS3_k127_7314745_0	1379698.RBG1_1C00001G0855	1.854e-127	437.0	COG0243@1|root,COG0243@2|Bacteria,2NPRJ@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	qrcB	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_7314745_8	478801.Ksed_16190	5.413e-06	55.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,1ZVC2@145357|Dermacoccaceae	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
CMS3_k127_7314745_1	234267.Acid_4435	3.863e-110	383.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7314745_6	1382306.JNIM01000001_gene1045	7.07e-61	218.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_7314745_7	646529.Desaci_3601	7.335e-49	194.0	COG4585@1|root,COG4585@2|Bacteria,1TR88@1239|Firmicutes,250AK@186801|Clostridia,264XI@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PAS_9
CMS3_k127_7314745_3	485913.Krac_5027	8.961e-83	296.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_7317504_1	426117.M446_2285	8.354e-05	49.0	COG0438@1|root,COG0438@2|Bacteria,1R7YV@1224|Proteobacteria,2UGA4@28211|Alphaproteobacteria,1JRMD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_7317504_0	402777.KB235904_gene4630	1.403e-143	468.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,1H97S@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS3_k127_7320254_0	351607.Acel_2103	0.0001147	45.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4ESRA@85013|Frankiales	201174|Actinobacteria	S	HAD-superfamily hydrolase, subfamily IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS3_k127_7325447_4	111781.Lepto7376_0158	6.585e-17	95.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
CMS3_k127_7325447_2	321332.CYB_1515	8.345e-34	151.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1GZAT@1129|Synechococcus	1117|Cyanobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_7325447_0	552811.Dehly_0558	1.165e-91	332.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_7325447_1	243164.DET0571	5.89e-53	205.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_7325447_3	1379698.RBG1_1C00001G0366	2.222e-19	99.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	Reg_prop,Y_Y_Y
CMS3_k127_7325857_8	349521.HCH_03661	3.812e-56	209.0	2DZNQ@1|root,32VEU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7325857_10	479434.Sthe_2271	8.542e-23	112.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_7325857_2	1499967.BAYZ01000177_gene5755	6.862e-194	634.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
CMS3_k127_7325857_1	526227.Mesil_0256	7.5e-228	756.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
CMS3_k127_7325857_7	357808.RoseRS_0705	1.735e-79	271.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS3_k127_7325857_5	926550.CLDAP_29050	7.501e-117	391.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
CMS3_k127_7325857_6	329726.AM1_5603	1.155e-89	304.0	COG1136@1|root,COG1136@2|Bacteria,1G4GN@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
CMS3_k127_7325857_0	111781.Lepto7376_4064	8.714e-281	888.0	COG0577@1|root,COG0577@2|Bacteria,1G04T@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_7325857_4	1385935.N836_22590	6.723e-139	452.0	COG5621@1|root,COG5621@2|Bacteria,1G3K9@1117|Cyanobacteria	1117|Cyanobacteria	H	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9,polyprenyl_synt
CMS3_k127_7325857_3	867845.KI911784_gene3021	1.776e-151	492.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS3_k127_7325857_9	1122221.JHVI01000014_gene1395	2.769e-50	186.0	COG0560@1|root,COG0560@2|Bacteria,1WKQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
CMS3_k127_7326070_0	485913.Krac_6991	1.242e-114	397.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_7326070_1	1489678.RDMS_10495	1.757e-55	214.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	nsr	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41
CMS3_k127_7326070_2	760192.Halhy_6444	8.356e-20	98.0	2E1NE@1|root,32WZB@2|Bacteria,4NU37@976|Bacteroidetes,1ITTK@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7330055_10	765420.OSCT_0188	2.343e-29	121.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi,375FS@32061|Chloroflexia	32061|Chloroflexia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS3_k127_7330055_9	1313301.AUGC01000006_gene106	2.587e-30	123.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS3_k127_7330055_7	861360.AARI_23370	1.528e-47	175.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,1W96W@1268|Micrococcaceae	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS3_k127_7330055_12	1121926.AXWO01000002_gene1557	5.66e-28	114.0	COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4EYVR@85014|Glycomycetales	201174|Actinobacteria	J	Ribosomal protein S17	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS3_k127_7330055_14	1238182.C882_0608	5.4e-09	63.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,2JUAU@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS3_k127_7330055_5	864702.OsccyDRAFT_3433	3.707e-54	194.0	COG0197@1|root,COG0197@2|Bacteria,1G55B@1117|Cyanobacteria,1HARZ@1150|Oscillatoriales	1117|Cyanobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS3_k127_7330055_2	926569.ANT_10100	1.131e-74	256.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi	200795|Chloroflexi	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS3_k127_7330055_11	926569.ANT_10090	1.628e-28	118.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi	200795|Chloroflexi	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS3_k127_7330055_8	867903.ThesuDRAFT_00563	3.352e-40	150.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WCJE@538999|Clostridiales incertae sedis	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS3_k127_7330055_1	926569.ANT_10070	4.041e-126	409.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS3_k127_7330055_13	926550.CLDAP_04080	6.243e-21	95.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi	200795|Chloroflexi	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS3_k127_7330055_4	926569.ANT_10050	1.799e-54	199.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS3_k127_7330055_3	357808.RoseRS_1185	4.767e-69	240.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,375C3@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS3_k127_7330055_6	926569.ANT_10030	6.125e-49	177.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS3_k127_7330055_0	479434.Sthe_1034	2.643e-202	636.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS3_k127_7336820_1	926550.CLDAP_23400	2.124e-116	392.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7336820_2	926550.CLDAP_23410	2.643e-20	96.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7336820_3	1463900.JOIX01000098_gene7529	3.58e-14	78.0	2B1NX@1|root,31U4E@2|Bacteria,2GTFZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7336820_0	102129.Lepto7375DRAFT_2011	2.29e-167	558.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_7336820_4	1540257.JQMW01000004_gene368	1.389e-06	53.0	29UV3@1|root,316MX@2|Bacteria,1UH1R@1239|Firmicutes,24QZD@186801|Clostridia,36VDG@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
CMS3_k127_7337610_0	357808.RoseRS_2450	1.249e-222	713.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,376ZJ@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_7342207_0	404380.Gbem_1014	7.617e-168	544.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,43STY@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase, family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
CMS3_k127_7342207_1	1499967.BAYZ01000095_gene4087	1.04e-41	158.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_7346231_1	1303518.CCALI_02791	7.558e-12	78.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,Guanylate_cyc,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS3_k127_7349722_1	1128421.JAGA01000002_gene1694	1.018e-36	150.0	COG2176@1|root,COG2378@1|root,COG2176@2|Bacteria,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	dnaQ	-	2.7.7.7	ko:K02342,ko:K03763,ko:K13573	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03051,ko03400	-	-	-	GIY-YIG,RNase_T,VRR_NUC,WYL
CMS3_k127_7349722_2	706587.Desti_4215	5.305e-35	143.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CMS3_k127_7349722_0	498761.HM1_2746	5.967e-90	308.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia	186801|Clostridia	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS3_k127_7349722_3	211114.JOEF01000002_gene4041	4.432e-05	55.0	2DR37@1|root,339ZB@2|Bacteria,2ISNH@201174|Actinobacteria,4E5TP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7351499_1	926569.ANT_00470	1.574e-88	299.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_7351499_0	306281.AJLK01000109_gene3196	6.553e-137	445.0	COG2146@1|root,COG2146@2|Bacteria,1G2KG@1117|Cyanobacteria,1JK9R@1189|Stigonemataceae	1117|Cyanobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
CMS3_k127_7354378_1	1297569.MESS2_350002	9.578e-37	141.0	COG0346@1|root,COG0346@2|Bacteria,1N8P0@1224|Proteobacteria,2UFWJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_7354378_0	1242864.D187_008760	3.826e-149	479.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,1Q3Q7@1224|Proteobacteria,4342C@68525|delta/epsilon subdivisions,2X4TK@28221|Deltaproteobacteria,2YZJY@29|Myxococcales	28221|Deltaproteobacteria	T	PNKP adenylyltransferase domain, ligase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
CMS3_k127_7360733_0	1128421.JAGA01000002_gene967	3.787e-88	306.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_7360733_1	926550.CLDAP_03000	1.285e-60	213.0	COG0622@1|root,COG0622@2|Bacteria,2G7DJ@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS3_k127_7360733_2	439235.Dalk_2700	5.077e-34	138.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
CMS3_k127_7369344_0	1128421.JAGA01000003_gene3086	8.946e-272	850.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_7369344_2	1469607.KK073769_gene5662	2.627e-72	252.0	COG3910@1|root,COG3910@2|Bacteria,1GEIW@1117|Cyanobacteria	1117|Cyanobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
CMS3_k127_7369344_1	864051.BurJ1DRAFT_0837	4.035e-90	308.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2VIQ7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_7369717_6	926550.CLDAP_23390	2.446e-32	141.0	COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_7369717_0	1128421.JAGA01000002_gene1751	8.749e-152	489.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
CMS3_k127_7369717_2	926550.CLDAP_17040	8.274e-96	345.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS3_k127_7369717_7	395495.Lcho_3739	6.108e-24	119.0	COG0689@1|root,COG5276@1|root,COG0689@2|Bacteria,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria	1224|Proteobacteria	N	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,He_PIG,LVIVD
CMS3_k127_7369717_5	1114922.CIFAM_17_01930	5.049e-38	154.0	COG2227@1|root,COG2519@1|root,COG2227@2|Bacteria,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,1RSIH@1236|Gammaproteobacteria,3WWXF@544|Citrobacter	1236|Gammaproteobacteria	HJ	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS3_k127_7369717_1	216594.MMAR_3322	4.236e-107	359.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,233TJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_7369717_3	216594.MMAR_3323	2.636e-66	239.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,234F0@1762|Mycobacteriaceae	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS3_k127_7369717_4	649638.Trad_0562	5.635e-42	163.0	COG1272@1|root,COG1272@2|Bacteria,1WK6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS3_k127_7379036_4	644076.SCH4B_0137	0.0008562	43.0	COG2929@1|root,COG2929@2|Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS3_k127_7379036_3	402777.KB235903_gene2202	9.365e-19	91.0	COG3514@1|root,COG3514@2|Bacteria,1G8GN@1117|Cyanobacteria,1HDPR@1150|Oscillatoriales	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
CMS3_k127_7379036_1	1172188.KB911820_gene2389	7.507e-59	214.0	COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria,4FH1S@85021|Intrasporangiaceae	201174|Actinobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS3_k127_7379036_0	1380370.JIBA01000010_gene2364	2.254e-149	479.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FFZ1@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_7379036_2	358220.C380_06485	1.883e-28	117.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_7379962_5	1122182.KB903821_gene1273	0.0009028	47.0	2B3DA@1|root,31W23@2|Bacteria,2INNH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7379962_1	102129.Lepto7375DRAFT_0196	1.001e-129	428.0	COG0657@1|root,COG0657@2|Bacteria,1G229@1117|Cyanobacteria,1HA06@1150|Oscillatoriales	1117|Cyanobacteria	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_7379962_3	446470.Snas_5852	2.091e-18	93.0	2EIQA@1|root,33CFR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7379962_4	526225.Gobs_1679	3.415e-11	66.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4EWV7@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7379962_2	32057.KB217478_gene90	9.332e-105	348.0	COG0596@1|root,COG0596@2|Bacteria,1GJMM@1117|Cyanobacteria,1HSGW@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_7379962_0	42256.RradSPS_0358	5.829e-146	496.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS3_k127_738349_3	383372.Rcas_3701	1.411e-29	139.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS3_k127_738349_2	216594.MMAR_3398	7.572e-51	209.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2GNXG@201174|Actinobacteria,23296@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknD	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NHL,Pkinase,PknH_C
CMS3_k127_738349_0	1464048.JNZS01000049_gene4757	2.218e-180	623.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4D8IB@85008|Micromonosporales	201174|Actinobacteria	O	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
CMS3_k127_738349_1	1403819.BATR01000022_gene806	4.282e-152	513.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
CMS3_k127_738349_4	314278.NB231_12069	1.621e-07	60.0	291G3@1|root,33XP4@2|Bacteria,1NW6I@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7385567_1	290397.Adeh_3289	1.464e-62	237.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1NKQ0@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_7385567_3	743525.TSC_c11660	1.395e-31	134.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1WKSF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_7385567_0	926560.KE387027_gene707	4.294e-83	280.0	COG1765@1|root,COG1765@2|Bacteria,1WM1H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_7385567_2	1123024.AUII01000052_gene3914	7.637e-58	208.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_7385567_4	1191523.MROS_2333	9.988e-30	118.0	COG0362@1|root,COG0362@2|Bacteria	2|Bacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS3_k127_7387550_2	472759.Nhal_0729	4.574e-82	278.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,1X2NF@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
CMS3_k127_7387550_1	1125863.JAFN01000001_gene2741	2.942e-121	406.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria	1224|Proteobacteria	C	PFAM FAD linked oxidase domain protein	dld	GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.1.1.303,1.1.1.4,1.1.2.4,1.1.3.15	ko:K00004,ko:K00102,ko:K00104	ko00620,ko00630,ko00650,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map00650,map01100,map01110,map01120,map01130	-	R00197,R00475,R02855,R02946,R10504	RC00042,RC00044,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_7387550_0	768704.Desmer_1343	3.353e-125	434.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,25B73@186801|Clostridia,263UP@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, luxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS3_k127_7387550_4	68570.DC74_7711	4.645e-69	255.0	COG0815@1|root,COG0815@2|Bacteria,2GP8X@201174|Actinobacteria	201174|Actinobacteria	M	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_7387550_3	572547.Amico_0160	7.572e-76	268.0	COG0436@1|root,COG0436@2|Bacteria,3TAQC@508458|Synergistetes	508458|Synergistetes	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_7387550_5	404589.Anae109_3347	5.393e-29	122.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1NKQ0@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS3_k127_7390591_0	398527.Bphyt_5013	4.494e-91	304.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VZEK@28216|Betaproteobacteria,1K56M@119060|Burkholderiaceae	28216|Betaproteobacteria	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
CMS3_k127_7390591_1	357808.RoseRS_2229	1.871e-74	277.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_7392776_8	767029.HMPREF9154_2318	7.393e-19	86.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4DS40@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS3_k127_7392776_9	926569.ANT_19000	4.419e-09	62.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS3_k127_7392776_0	926569.ANT_18990	1.594e-83	281.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi	200795|Chloroflexi	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS3_k127_7392776_3	459495.SPLC1_S200730	9.184e-56	198.0	COG0080@1|root,COG0080@2|Bacteria,1G4ZJ@1117|Cyanobacteria,1HAME@1150|Oscillatoriales	1117|Cyanobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS3_k127_7392776_1	574376.BAMA_11565	2.282e-82	280.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS3_k127_7392776_7	693986.MOC_4385	2.421e-27	117.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2U592@28211|Alphaproteobacteria,1JRCW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS3_k127_7392776_5	935840.JAEQ01000017_gene1961	8.893e-46	168.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,43K11@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS3_k127_7392776_6	926569.ANT_02780	6.982e-45	170.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS3_k127_7392776_10	316274.Haur_1125	5.896e-06	56.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
CMS3_k127_7392776_4	1303518.CCALI_01754	3.252e-50	191.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_7392776_2	926569.ANT_19070	1.388e-75	258.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
CMS3_k127_7394642_8	449447.MAE_26720	1.278e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria	1117|Cyanobacteria	U	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
CMS3_k127_7394642_2	1183438.GKIL_2176	3.381e-64	239.0	COG1372@1|root,COG4409@1|root,COG1372@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Phage_Mu_F,RHS_repeat
CMS3_k127_7394642_0	1128421.JAGA01000003_gene3216	6.124e-163	524.0	COG0438@1|root,COG0438@2|Bacteria,2NR53@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like domain	rgpA	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	DUF1972,Glyco_trans_1_4,Glycos_transf_1
CMS3_k127_7394642_5	1502851.FG93_00825	2.43e-20	98.0	COG0500@1|root,COG2226@2|Bacteria,1RF1C@1224|Proteobacteria,2U86S@28211|Alphaproteobacteria,3JXW1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_7394642_1	765420.OSCT_1804	3.909e-70	252.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7394642_3	326427.Cagg_1652	5.866e-43	175.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7394642_10	1236902.ANAS01000020_gene1793	9.372e-06	58.0	COG2244@1|root,COG2244@2|Bacteria,2I4II@201174|Actinobacteria,4EGAH@85012|Streptosporangiales	201174|Actinobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_C
CMS3_k127_7394642_11	383372.Rcas_4268	2.448e-05	57.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi,375HE@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_7394642_12	1163617.SCD_n01352	0.000164	54.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria	28216|Betaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
CMS3_k127_7394642_9	1040982.AXAL01000038_gene141	3.758e-08	65.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2TTBW@28211|Alphaproteobacteria,43KPY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
CMS3_k127_7394642_7	926569.ANT_09180	7.922e-15	87.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K13009,ko:K18814	-	-	-	-	ko00000,ko01000,ko01005,ko02000	9.B.67.1	-	-	Wzy_C
CMS3_k127_7394642_6	765420.OSCT_2098	3.507e-18	96.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi,376E4@32061|Chloroflexia	32061|Chloroflexia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7396143_8	926569.ANT_25700	1.185e-26	111.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_7396143_2	794903.OPIT5_05425	2.841e-105	354.0	COG2334@1|root,COG2334@2|Bacteria,46TIS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_7396143_0	926550.CLDAP_15630	3.631e-212	676.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS3_k127_7396143_5	926550.CLDAP_35280	1.066e-59	216.0	COG0454@1|root,COG0456@2|Bacteria,2G91C@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_7396143_6	410358.Mlab_1692	1.706e-48	183.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y4MT@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
CMS3_k127_7396143_1	1167006.UWK_00703	4.522e-169	556.0	COG0038@1|root,COG0517@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG0569@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
CMS3_k127_7396143_4	1304284.L21TH_2322	2.258e-89	306.0	COG0789@1|root,COG0789@2|Bacteria,1UPFX@1239|Firmicutes,24VIV@186801|Clostridia	186801|Clostridia	K	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7396143_7	709986.Deima_0245	3.811e-38	145.0	COG2329@1|root,COG2329@2|Bacteria,1WK6V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS3_k127_7396143_3	926569.ANT_12110	3.323e-94	318.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	2.7.7.6	ko:K03046,ko:K03641,ko:K08642	ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400	2.C.1.2	-	-	Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23
CMS3_k127_7404772_0	1167006.UWK_01323	2.108e-178	566.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_7404772_1	266117.Rxyl_2848	1.548e-119	392.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4CQAT@84995|Rubrobacteria	84995|Rubrobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_7422717_1	1095769.CAHF01000014_gene3157	2.747e-58	206.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,475VS@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD3	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS3_k127_7422717_0	316274.Haur_0358	1.145e-197	629.0	COG0277@1|root,COG0277@2|Bacteria,2G8D5@200795|Chloroflexi	200795|Chloroflexi	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_7422717_2	1122918.KB907255_gene2485	1.015e-32	131.0	COG0666@1|root,COG0666@2|Bacteria,1UMTI@1239|Firmicutes,4HP9C@91061|Bacilli,26ZGT@186822|Paenibacillaceae	91061|Bacilli	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_742320_2	13035.Dacsa_3476	3.504e-18	85.0	COG2026@1|root,COG2026@2|Bacteria,1GABP@1117|Cyanobacteria	1117|Cyanobacteria	DJ	Addiction module toxin, RelE StbE family	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CMS3_k127_742320_3	111780.Sta7437_0529	6.946e-18	84.0	2CAX8@1|root,33CC9@2|Bacteria,1GB0V@1117|Cyanobacteria,3VN6J@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_742320_1	195250.CM001776_gene3527	2.046e-167	537.0	COG0075@1|root,COG0075@2|Bacteria,1G2P6@1117|Cyanobacteria,1GYBY@1129|Synechococcus	1117|Cyanobacteria	E	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	spt	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_742320_0	926550.CLDAP_19740	3.067e-262	826.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi	200795|Chloroflexi	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
CMS3_k127_7437856_1	1121918.ARWE01000001_gene3097	4.218e-68	239.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,42S4C@68525|delta/epsilon subdivisions,2WNXY@28221|Deltaproteobacteria,43T1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_7437856_0	926550.CLDAP_02810	1.465e-198	638.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS3_k127_7437856_2	926569.ANT_30110	9.827e-49	184.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CMS3_k127_7445220_0	643473.KB235930_gene1765	1.984e-34	139.0	COG5542@1|root,COG5542@2|Bacteria,1GDW7@1117|Cyanobacteria,1HIN0@1161|Nostocales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7445220_1	936140.AEOT01000011_gene428	8.959e-17	91.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,3F3W3@33958|Lactobacillaceae	91061|Bacilli	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS3_k127_7445932_0	926569.ANT_20730	5.453e-140	452.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS3_k127_7445932_4	1254432.SCE1572_28975	6.455e-53	193.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS3_k127_7445932_6	930169.B5T_00506	1.31e-09	65.0	2B29B@1|root,31UT4@2|Bacteria,1QSNC@1224|Proteobacteria,1SVX3@1236|Gammaproteobacteria,1XQK1@135619|Oceanospirillales	135619|Oceanospirillales	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
CMS3_k127_7445932_3	574087.Acear_1013	5.136e-97	331.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,3WAA2@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_7445932_1	926569.ANT_29200	4.742e-119	406.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
CMS3_k127_7445932_2	926569.ANT_29200	9.377e-100	351.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
CMS3_k127_7445932_5	1177154.Y5S_00820	4.912e-15	80.0	2DR3R@1|root,33A1G@2|Bacteria,1NK41@1224|Proteobacteria,1SGHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
CMS3_k127_7445932_7	926569.ANT_23670	0.0005673	46.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS3_k127_7449511_4	604331.AUHY01000002_gene1191	6.295e-28	117.0	COG0491@1|root,COG0491@2|Bacteria,1WJ5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_7449511_0	765420.OSCT_0643	2.198e-140	472.0	COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi,3767N@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7449511_1	765420.OSCT_0642	2.631e-101	336.0	COG2197@1|root,COG2197@2|Bacteria,2G7U4@200795|Chloroflexi,376QK@32061|Chloroflexia	32061|Chloroflexia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_7449511_6	1121946.AUAX01000031_gene1023	1.383e-24	113.0	COG0454@1|root,COG0456@2|Bacteria,2I2W1@201174|Actinobacteria,4DD5J@85008|Micromonosporales	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,FR47
CMS3_k127_7449511_2	1242864.D187_003500	1.04e-69	261.0	COG0642@1|root,COG2205@2|Bacteria	1242864.D187_003500|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7449511_7	1268635.Loa_02790	1.118e-20	94.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1JF0Q@118969|Legionellales	118969|Legionellales	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS3_k127_7449511_3	390989.JOEG01000035_gene1758	2.939e-63	226.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DAR4@85008|Micromonosporales	201174|Actinobacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_7449511_5	1089550.ATTH01000001_gene2123	1.156e-25	115.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,1FIWR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_7452863_3	1485545.JQLW01000008_gene1984	1.559e-19	94.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria	1224|Proteobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_7452863_2	1124780.ANNU01000035_gene265	2.849e-31	130.0	COG0457@1|root,COG0457@2|Bacteria,4NXA2@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7452863_1	927677.ALVU02000001_gene2197	7.674e-48	186.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	walN	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7452863_4	1385935.N836_31920	4.605e-19	98.0	COG0615@1|root,COG0615@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_7452863_0	926569.ANT_14870	5.936e-220	713.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_7454116_4	416591.Tlet_0452	4.342e-05	47.0	COG0462@1|root,COG0462@2|Bacteria,2GCBG@200918|Thermotogae	200918|Thermotogae	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1628	Pribosyl_synth,Pribosyltran_N
CMS3_k127_7454116_1	926550.CLDAP_14970	7.958e-102	340.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_7454116_2	525904.Tter_1673	2.356e-55	196.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CMS3_k127_7454116_0	1128421.JAGA01000002_gene1742	4.374e-224	713.0	COG1331@1|root,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_7454116_3	326427.Cagg_2385	6.046e-38	161.0	COG4166@1|root,COG4166@2|Bacteria,2G8A0@200795|Chloroflexi,375R9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_7454488_0	765912.Thimo_0216	6.359e-64	237.0	COG0845@1|root,COG1357@1|root,COG2319@1|root,COG5635@1|root,COG0845@2|Bacteria,COG1357@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,1S1AJ@1236|Gammaproteobacteria,1WXXD@135613|Chromatiales	135613|Chromatiales	M	PFAM WD40 repeat, subgroup	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,WD40
CMS3_k127_747646_1	395961.Cyan7425_4542	1.441e-120	391.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,1G43E@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Calcineurin-like phosphoesterase	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase,RNA_lig_T4_1
CMS3_k127_747646_0	483219.LILAB_12420	6.636e-182	581.0	COG2227@1|root,COG2227@2|Bacteria,1R6E0@1224|Proteobacteria,42ZTU@68525|delta/epsilon subdivisions,2WVFC@28221|Deltaproteobacteria,2YZN2@29|Myxococcales	28221|Deltaproteobacteria	H	RNA repair, ligase-Pnkp-associating, region of Hen1	ubiE2	-	-	-	-	-	-	-	-	-	-	-	Hen1_L,Methyltransf_23
CMS3_k127_747646_3	469383.Cwoe_5842	3.966e-26	111.0	COG0640@1|root,COG0640@2|Bacteria,2GS7J@201174|Actinobacteria,4CT34@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_747646_2	485913.Krac_4792	1.673e-28	121.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_7477410_0	886293.Sinac_6192	7.453e-175	559.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,2IXJN@203682|Planctomycetes	203682|Planctomycetes	G	alpha amylase catalytic	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
CMS3_k127_7477410_3	1200792.AKYF01000023_gene904	0.0003014	47.0	COG1225@1|root,COG1225@2|Bacteria,1V24A@1239|Firmicutes,4HFUX@91061|Bacilli,26R0T@186822|Paenibacillaceae	91061|Bacilli	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_7477410_2	768671.ThimaDRAFT_4838	5.914e-15	78.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,1SYRE@1236|Gammaproteobacteria,1X1HE@135613|Chromatiales	135613|Chromatiales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_7477410_1	1128421.JAGA01000002_gene1623	9.41e-34	136.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	ybaK	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS3_k127_7482929_1	1122603.ATVI01000012_gene1197	2.183e-144	467.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RN6S@1236|Gammaproteobacteria,1X3SK@135614|Xanthomonadales	135614|Xanthomonadales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_7482929_4	644801.Psest_0503	5.007e-46	171.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S72R@1236|Gammaproteobacteria,1Z24N@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	COG2030 Acyl dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS3_k127_7482929_0	1128421.JAGA01000002_gene1199	8.831e-229	718.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS3_k127_7482929_7	485913.Krac_8724	3.313e-27	118.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_7482929_8	491952.Mar181_1164	2.013e-16	83.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_7482929_2	1120949.KB903329_gene9217	2.381e-105	377.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
CMS3_k127_7482929_5	382464.ABSI01000005_gene1264	6.518e-35	139.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS3_k127_7482929_6	187303.BN69_1956	1.045e-33	135.0	COG3791@1|root,COG3791@2|Bacteria,1RCXS@1224|Proteobacteria,2U814@28211|Alphaproteobacteria,37015@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7482929_3	926569.ANT_09340	6.561e-87	302.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_7490089_1	926550.CLDAP_37440	4.198e-116	398.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
CMS3_k127_7490089_2	1121937.AUHJ01000006_gene2470	3.194e-78	282.0	COG1404@1|root,COG1404@2|Bacteria,1N6G1@1224|Proteobacteria,1RSME@1236|Gammaproteobacteria,468YY@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
CMS3_k127_7490089_3	316274.Haur_4061	2.434e-41	170.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_7490089_0	926569.ANT_30500	5.992e-162	537.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
CMS3_k127_7493604_0	909613.UO65_1096	1.323e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,4E2HU@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7493604_3	324602.Caur_3113	4.757e-10	72.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7493604_2	926569.ANT_25610	5.52e-14	84.0	COG4254@1|root,COG4254@2|Bacteria,2G9J2@200795|Chloroflexi	200795|Chloroflexi	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS3_k127_7493604_1	926569.ANT_25610	9.486e-19	99.0	COG4254@1|root,COG4254@2|Bacteria,2G9J2@200795|Chloroflexi	200795|Chloroflexi	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS3_k127_7497389_1	1230457.C476_02902	1.206e-97	330.0	COG0667@1|root,arCOG01617@2157|Archaea,2XSTY@28890|Euryarchaeota,23RYU@183963|Halobacteria	183963|Halobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_7497389_2	485913.Krac_2663	6.711e-28	124.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_6,Acetyltransf_7,Acetyltransf_9
CMS3_k127_7497389_3	1122604.JONR01000002_gene1604	1.018e-12	80.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1X3CZ@135614|Xanthomonadales	135614|Xanthomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS3_k127_7497389_0	485913.Krac_6032	3.354e-146	487.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_7498261_2	744979.R2A130_3201	2.797e-11	71.0	COG2114@1|root,COG2114@2|Bacteria,1MWHK@1224|Proteobacteria,2TR2J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_7498261_3	1242864.D187_003442	4.123e-09	67.0	28YX4@1|root,2ZKQ7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7498261_0	318424.EU78_26750	1.637e-12	68.0	COG2232@1|root,COG2232@2|Bacteria,2HPI0@201174|Actinobacteria,235H6@1762|Mycobacteriaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
CMS3_k127_7507865_4	316274.Haur_0008	1.717e-31	126.0	COG2110@1|root,COG2110@2|Bacteria,2GAYN@200795|Chloroflexi,377JN@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_7507865_2	357808.RoseRS_0656	3.449e-47	183.0	COG3021@1|root,COG3021@2|Bacteria,2G9DW@200795|Chloroflexi,377KI@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_7507865_5	1121377.KB906404_gene2858	1.094e-25	116.0	COG3393@1|root,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,FR47,GNAT_acetyltran
CMS3_k127_7507865_0	221288.JH992901_gene3895	8.84e-150	483.0	COG0715@1|root,COG0715@2|Bacteria,1GFIM@1117|Cyanobacteria	1117|Cyanobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CMS3_k127_7507865_3	1120949.KB903294_gene4071	4.183e-39	151.0	COG4978@1|root,COG4978@2|Bacteria	2|Bacteria	-	-	MA20_43725	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,Polyketide_cyc2
CMS3_k127_7507865_1	649638.Trad_2162	4.794e-52	188.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_7513828_2	1313172.YM304_31580	8.354e-47	170.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_7513828_1	388401.RB2150_04638	5.696e-49	183.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	gstF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1,GST_C,GST_N_3
CMS3_k127_7513828_0	1089548.KI783301_gene128	1.905e-87	298.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HB9D@91061|Bacilli,3WFA2@539002|Bacillales incertae sedis	91061|Bacilli	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CBM_6,Cadherin-like,DUF1533,F5_F8_type_C,FIVAR,Glyco_hydro_16,SLH
CMS3_k127_7513828_3	1499967.BAYZ01000138_gene188	6.883e-37	144.0	COG0395@1|root,COG0395@2|Bacteria,2NPBC@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	thuG	-	-	ko:K02026,ko:K10238	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
CMS3_k127_751591_2	379066.GAU_2012	5.894e-08	54.0	COG5002@1|root,COG5002@2|Bacteria,1ZTF2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_751591_1	671143.DAMO_2817	6.878e-36	150.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2NR3P@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	cpxA	-	2.7.13.3	ko:K02484,ko:K07640,ko:K07643,ko:K07645,ko:K07649,ko:K19609	ko01503,ko02020,ko02024,map01503,map02020,map02024	M00447,M00451,M00453,M00457,M00721,M00722,M00727,M00728,M00770	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,CpxA_peri,HAMP,HATPase_c,HK_sensor,HisKA
CMS3_k127_751591_0	324602.Caur_2863	7.509e-61	216.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_751851_3	1444711.CCJF01000005_gene1467	1.659e-45	169.0	COG2346@1|root,COG2346@2|Bacteria,2JH1G@204428|Chlamydiae	204428|Chlamydiae	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_751851_1	383372.Rcas_0337	4.349e-83	289.0	COG0491@1|root,COG0491@2|Bacteria,2GAIA@200795|Chloroflexi,376BC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_751851_0	485913.Krac_3059	1.605e-189	600.0	COG3844@1|root,COG3844@2|Bacteria,2G5K1@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS3_k127_751851_2	265729.GS18_0217400	7.354e-52	190.0	COG1878@1|root,COG1878@2|Bacteria,1U801@1239|Firmicutes,4HDQ3@91061|Bacilli,1ZD77@1386|Bacillus	91061|Bacilli	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
CMS3_k127_751851_5	521011.Mpal_2209	8.202e-07	59.0	COG0614@1|root,COG3291@1|root,arCOG02510@2157|Archaea,arCOG03611@2157|Archaea	2157|Archaea	P	PFAM PKD domain containing protein	ush	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	CBM_6,DUF839,NHL,NosD,PKD,Peptidase_C1,Peptidase_S8
CMS3_k127_751851_4	317936.Nos7107_4863	8.741e-32	139.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS3_k127_7521682_4	76114.ebD26	9.099e-14	71.0	COG2020@1|root,COG2020@2|Bacteria,1QVIW@1224|Proteobacteria,2VX8F@28216|Betaproteobacteria	28216|Betaproteobacteria	O	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_7521682_3	272569.rrnAC0082	9.918e-59	221.0	arCOG14225@1|root,arCOG14225@2157|Archaea,2XYCA@28890|Euryarchaeota,23W9H@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7521682_1	383372.Rcas_1175	1.46e-112	375.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GAJ1@200795|Chloroflexi,376G4@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_7521682_2	357808.RoseRS_0805	2.358e-83	282.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi,376Y5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_7521682_0	926550.CLDAP_30480	4.259e-233	734.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
CMS3_k127_7521682_5	517418.Ctha_0121	3.408e-08	57.0	COG0243@1|root,COG0243@2|Bacteria,1FDP0@1090|Chlorobi	1090|Chlorobi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_7534388_4	1197477.IA57_10535	0.0001279	54.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_7534388_3	1250278.JQNQ01000001_gene3405	4.425e-07	61.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_7534388_5	318996.AXAZ01000063_gene5733	0.0002518	51.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria,3JWD6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_7534388_2	290400.Jann_0646	7.941e-12	81.0	COG4191@1|root,COG4191@2|Bacteria,1MVK7@1224|Proteobacteria,2TR44@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	signal transduction histidine kinase	regM	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_7534388_1	867845.KI911784_gene2111	1.568e-20	109.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
CMS3_k127_7534388_0	698758.AXY_17390	5.228e-21	111.0	COG2199@1|root,COG3706@2|Bacteria,1TT1S@1239|Firmicutes,4IQ50@91061|Bacilli	91061|Bacilli	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
CMS3_k127_7540416_2	383372.Rcas_3361	2.575e-65	232.0	COG0548@1|root,COG0548@2|Bacteria,2G6ZG@200795|Chloroflexi,375PI@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_7540416_1	383372.Rcas_3362	3.515e-105	356.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,3759I@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_7540416_0	926569.ANT_15960	6.291e-139	451.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS3_k127_7540416_5	398512.JQKC01000002_gene1698	2.33e-05	55.0	COG1388@1|root,COG1388@2|Bacteria,1UVES@1239|Firmicutes,25PNW@186801|Clostridia,3WQA0@541000|Ruminococcaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_7540416_4	1121926.AXWO01000007_gene56	1.429e-23	107.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K01163,ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS3_k127_7541642_0	1232437.KL661958_gene2870	3.024e-154	505.0	COG0475@1|root,COG0569@1|root,COG1762@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,1R9PF@1224|Proteobacteria,42RF1@68525|delta/epsilon subdivisions,2WMJJ@28221|Deltaproteobacteria,2MJ88@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,PTS_EIIA_2,TrkA_C,TrkA_N
CMS3_k127_7541642_2	383372.Rcas_1749	2.579e-69	244.0	COG2360@1|root,COG2360@2|Bacteria,2G8HE@200795|Chloroflexi,375I4@32061|Chloroflexia	32061|Chloroflexia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS3_k127_7541642_1	926550.CLDAP_16250	1.601e-96	329.0	COG0477@1|root,COG2814@2|Bacteria,2G7NY@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_7541642_3	1242864.D187_007688	2.489e-46	175.0	COG2197@1|root,COG2197@2|Bacteria,1NCBR@1224|Proteobacteria,433WZ@68525|delta/epsilon subdivisions,2X3XU@28221|Deltaproteobacteria,2YXHT@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS3_k127_7541642_4	1278073.MYSTI_00292	1.004e-26	111.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YWNQ@29|Myxococcales	28221|Deltaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_7553434_1	518766.Rmar_2051	4.592e-30	121.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1FJ3C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_7553434_0	478741.JAFS01000002_gene71	1.001e-245	775.0	COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,37G0P@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS3_k127_7554377_0	1122214.AQWH01000003_gene4062	3.39e-127	410.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2PKRY@255475|Aurantimonadaceae	28211|Alphaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	MA20_32395	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_7554377_2	1236976.JCM16418_503	2.978e-16	81.0	2DPPC@1|root,332VC@2|Bacteria,1VM0N@1239|Firmicutes,4HNHT@91061|Bacilli,26ZTB@186822|Paenibacillaceae	91061|Bacilli	S	Negative regulatory protein YxlE	yxlE	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
CMS3_k127_7554377_1	255470.cbdbA1715	4.897e-40	154.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,34CZ8@301297|Dehalococcoidia	301297|Dehalococcoidia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_7555976_16	498761.HM1_0837	3.999e-19	89.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia	186801|Clostridia	G	phosphocarrier, HPr family	ptsH	-	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	-	PTS-HPr
CMS3_k127_7555976_9	316274.Haur_1527	7.65e-56	198.0	COG4668@1|root,COG4668@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	mtlA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015166,GO:0015318,GO:0015575,GO:0015791,GO:0015797,GO:0015850,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090565,GO:1901618	2.7.1.197,2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02798,ko:K02799,ko:K02800,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273,M00274	R02704,R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	iAPECO1_1312.APECO1_2858,iEC042_1314.EC042_3906,iECIAI39_1322.ECIAI39_4114,iECOK1_1307.ECOK1_4040,iECS88_1305.ECS88_4012,iECUMN_1333.ECUMN_4110,iUMN146_1321.UM146_18140,iUTI89_1310.UTI89_C4137	PTS_EIIA_2,PTS_EIIC,PTS_IIB
CMS3_k127_7555976_13	316274.Haur_1526	3.871e-27	114.0	COG2213@1|root,COG2213@2|Bacteria	2|Bacteria	G	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
CMS3_k127_7555976_3	316274.Haur_1525	1.729e-147	475.0	COG2213@1|root,COG2213@2|Bacteria	2|Bacteria	G	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
CMS3_k127_7555976_6	316274.Haur_1524	2.077e-111	377.0	COG3711@1|root,COG3711@2|Bacteria	2|Bacteria	K	transcriptional antiterminator	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
CMS3_k127_7555976_14	926569.ANT_22100	3.273e-26	113.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS3_k127_7555976_15	926569.ANT_22090	6.134e-21	96.0	COG1006@1|root,COG1006@2|Bacteria	2|Bacteria	P	Multisubunit Na H antiporter MnhC subunit	mnhC	-	1.6.5.3	ko:K00340,ko:K05567	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Oxidored_q2
CMS3_k127_7555976_1	926569.ANT_08400	5.012e-174	566.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	200795|Chloroflexi	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS3_k127_7555976_4	926569.ANT_22070	1.758e-120	405.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	mrpD	-	1.6.5.3	ko:K00342,ko:K00343,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS3_k127_7555976_8	926569.ANT_22050	2.794e-71	245.0	COG3260@1|root,COG3260@2|Bacteria,2G8XX@200795|Chloroflexi	200795|Chloroflexi	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	echC	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
CMS3_k127_7555976_12	926569.ANT_22040	6.103e-28	121.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
CMS3_k127_7555976_2	926569.ANT_22030	5.371e-166	531.0	COG3261@1|root,COG3261@2|Bacteria,2G8BA@200795|Chloroflexi	200795|Chloroflexi	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	ko:K14090	-	-	-	-	ko00000	-	-	-	Complex1_49kDa,NiFeSe_Hases
CMS3_k127_7555976_5	926569.ANT_22020	1.226e-117	387.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS3_k127_7555976_11	926569.ANT_22010	3.25e-40	153.0	COG1143@1|root,COG1143@2|Bacteria,2G9SP@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	ko:K14091	-	-	-	-	ko00000	-	-	-	Fer4
CMS3_k127_7555976_17	926569.ANT_22000	1.118e-15	85.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	-	-	3.4.23.51	ko:K00442,ko:K08315	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000,ko01002	-	-	-	HycI
CMS3_k127_7555976_7	479434.Sthe_2328	3.367e-74	258.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,27Z66@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7555976_10	304371.MCP_0732	3.982e-43	163.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_7555976_0	1121428.DESHY_110052___1	2.573e-240	774.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0182	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
CMS3_k127_7563610_0	1173028.ANKO01000065_gene5619	1.293e-195	644.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,1H919@1150|Oscillatoriales	1117|Cyanobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
CMS3_k127_7563610_1	1122939.ATUD01000013_gene869	8.948e-67	252.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7592914_1	1089548.KI783301_gene1779	3.53e-32	141.0	COG3055@1|root,COG4412@1|root,COG5184@1|root,COG3055@2|Bacteria,COG4412@2|Bacteria,COG5184@2|Bacteria,1VW0A@1239|Firmicutes,4HWE6@91061|Bacilli,3WFP4@539002|Bacillales incertae sedis	2|Bacteria	DZ	S-layer homology domain	-	-	3.2.1.18,3.2.1.52,3.2.1.8	ko:K01181,ko:K01186,ko:K12373,ko:K20276	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko02024,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map02024,map04142	M00079	R00022,R04018,R06004,R11316	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	-	GH20,GH33	-	DUF1929,DUF4347,F5_F8_type_C,FIVAR,He_PIG,HemolysinCabind,Kelch_1,Kelch_4,Laminin_G_3,SLH
CMS3_k127_7592914_0	1382306.JNIM01000001_gene3374	2.458e-111	371.0	COG2133@1|root,COG2133@2|Bacteria,2G7VF@200795|Chloroflexi	200795|Chloroflexi	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_7592914_2	1121019.AUMN01000009_gene1925	2.244e-05	56.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,1WBAR@1268|Micrococcaceae	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_759363_3	1122611.KB903952_gene5866	3.188e-23	115.0	2C5BM@1|root,32RFE@2|Bacteria,2INA4@201174|Actinobacteria,4EJSN@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_759363_2	1385518.N798_04175	7.504e-24	117.0	2C5BM@1|root,32RFE@2|Bacteria,2INA4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_759363_4	1122611.KB903952_gene5866	0.0001846	53.0	2C5BM@1|root,32RFE@2|Bacteria,2INA4@201174|Actinobacteria,4EJSN@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_759363_0	383372.Rcas_3193	3.949e-161	512.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,377XY@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_759363_1	926550.CLDAP_22560	6.432e-94	319.0	COG0534@1|root,COG0534@2|Bacteria,2G78S@200795|Chloroflexi	200795|Chloroflexi	V	PFAM multi antimicrobial extrusion protein MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_7604953_7	324602.Caur_3196	6.636e-22	96.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
CMS3_k127_7604953_6	1170562.Cal6303_4754	6.318e-38	166.0	COG1672@1|root,COG1672@2|Bacteria,1G4AU@1117|Cyanobacteria,1HR0W@1161|Nostocales	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
CMS3_k127_7604953_3	357808.RoseRS_3845	2.784e-71	265.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_7604953_1	272134.KB731324_gene1598	7.674e-116	391.0	COG1073@1|root,COG1073@2|Bacteria,1G1MU@1117|Cyanobacteria	1117|Cyanobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_7604953_2	926550.CLDAP_00460	3.489e-72	257.0	COG2133@1|root,COG2133@2|Bacteria,2G7VF@200795|Chloroflexi	200795|Chloroflexi	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_7604953_5	518766.Rmar_1065	8.166e-57	215.0	COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_7604953_8	383372.Rcas_3330	3.47e-19	95.0	COG0406@1|root,COG0406@2|Bacteria,2G9HA@200795|Chloroflexi,377FR@32061|Chloroflexia	32061|Chloroflexia	G	PFAM Phosphoglycerate mutase	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS3_k127_7604953_0	1157490.EL26_11975	7.027e-119	407.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	PKD,PPC,Peptidase_M10,Peptidase_M28,SLH
CMS3_k127_7604953_4	383372.Rcas_2212	1.484e-64	229.0	COG0604@1|root,COG0604@2|Bacteria,2G8BS@200795|Chloroflexi,375P1@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_7606615_4	1128421.JAGA01000003_gene3155	4.762e-73	258.0	COG0130@1|root,COG0130@2|Bacteria,2NP9J@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
CMS3_k127_7606615_5	264732.Moth_1052	9.547e-57	210.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,42ER4@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM phosphoesterase, RecJ domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_7606615_9	926569.ANT_02240	1.935e-26	113.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi	200795|Chloroflexi	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS3_k127_7606615_0	273068.TTE1393	5.875e-184	593.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,42EP2@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS3_k127_7606615_11	479434.Sthe_1256	7.448e-22	98.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi,27YHF@189775|Thermomicrobia	189775|Thermomicrobia	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
CMS3_k127_7606615_2	926569.ANT_02270	1.462e-143	481.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi	200795|Chloroflexi	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CMS3_k127_7606615_6	926569.ANT_31200	3.266e-49	201.0	COG2203@1|root,COG3829@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_7606615_1	266117.Rxyl_0743	5.832e-163	524.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CMS3_k127_7606615_12	1382306.JNIM01000001_gene2571	1.32e-11	70.0	COG0526@1|root,COG0526@2|Bacteria,2G7HX@200795|Chloroflexi	200795|Chloroflexi	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_7606615_7	926550.CLDAP_00520	1.13e-42	161.0	2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
CMS3_k127_7606615_10	266117.Rxyl_0744	2.597e-26	111.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,4CQC7@84995|Rubrobacteria	84995|Rubrobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_7606615_8	518766.Rmar_1678	1.502e-28	121.0	COG1310@1|root,COG1310@2|Bacteria,4NTI0@976|Bacteroidetes,1FJCV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
CMS3_k127_7606615_3	1303518.CCALI_00534	2.005e-110	365.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_7607985_6	504728.K649_09085	8.852e-46	168.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	pcaC	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,CMD
CMS3_k127_7607985_1	504728.K649_09080	1.459e-110	361.0	COG3485@1|root,COG3485@2|Bacteria,1WM02@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
CMS3_k127_7607985_5	479434.Sthe_0604	1.497e-52	191.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	pcaG	-	1.13.11.3	ko:K00448	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
CMS3_k127_7607985_0	1123277.KB893185_gene2966	5.678e-177	560.0	COG0620@1|root,COG0620@2|Bacteria,4NJAH@976|Bacteroidetes,47MCD@768503|Cytophagia	976|Bacteroidetes	E	PFAM Methionine synthase vitamin-B12 independent	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_7607985_3	759362.KVU_1374	9.379e-70	243.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	branched-chain amino acid	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_7607985_2	383372.Rcas_2298	1.144e-79	273.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374YI@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS3_k127_7607985_4	903818.KI912268_gene1022	4.918e-53	204.0	COG0559@1|root,COG0559@2|Bacteria	2|Bacteria	E	leucine import across plasma membrane	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS3_k127_7607985_7	1243664.CAVL020000009_gene656	2.642e-35	143.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1ZBKN@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS3_k127_7612246_1	926550.CLDAP_19470	7.654e-125	440.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS3_k127_7612246_2	390989.JOEG01000001_gene5320	8.78e-05	54.0	2C5BM@1|root,32RFE@2|Bacteria,2INA4@201174|Actinobacteria,4DFG5@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7612246_0	744872.Spica_2714	2.154e-130	429.0	COG0495@1|root,COG0495@2|Bacteria,2J5BV@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS3_k127_761290_3	1242864.D187_009380	1.016e-60	218.0	COG0438@1|root,COG0463@1|root,COG1216@1|root,COG0438@2|Bacteria,COG0463@2|Bacteria,COG1216@2|Bacteria,1MX5Z@1224|Proteobacteria,42QBQ@68525|delta/epsilon subdivisions,2WNMH@28221|Deltaproteobacteria,2YWPD@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_2,Glycos_transf_2
CMS3_k127_761290_2	1195236.CTER_1970	1.853e-82	298.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_761290_1	926569.ANT_09310	4.148e-92	307.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_761290_0	926569.ANT_09320	9.65e-109	370.0	COG5002@1|root,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_7632978_0	717606.PaecuDRAFT_4143	1.289e-88	306.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,4HUSQ@91061|Bacilli,26V4Y@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7632978_1	717606.PaecuDRAFT_4144	1.91e-68	251.0	COG1216@1|root,COG3551@1|root,COG1216@2|Bacteria,COG3551@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	ko:K12992,ko:K20444	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Sulfotransfer_3
CMS3_k127_7632978_2	580327.Tthe_2188	3.748e-05	50.0	COG2227@1|root,COG2227@2|Bacteria,1VI0K@1239|Firmicutes,24W90@186801|Clostridia	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_7633082_6	649638.Trad_0848	4.719e-20	93.0	COG1960@1|root,COG1960@2|Bacteria,1WKVF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_7633082_5	1128421.JAGA01000002_gene728	7.825e-23	105.0	2DQ01@1|root,32UN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7633082_4	926550.CLDAP_36810	7.845e-33	131.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi	200795|Chloroflexi	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
CMS3_k127_7633082_0	926550.CLDAP_27450	1.081e-263	829.0	COG2183@1|root,COG2183@2|Bacteria,2G66S@200795|Chloroflexi	200795|Chloroflexi	K	Tex-like protein N-terminal domain	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CMS3_k127_7633082_7	1123278.KB893542_gene5527	3.05e-13	77.0	COG0203@1|root,COG3743@1|root,COG0203@2|Bacteria,COG3743@2|Bacteria,4NNW0@976|Bacteroidetes,47PPE@768503|Cytophagia	976|Bacteroidetes	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS3_k127_7633082_3	357808.RoseRS_1507	1.184e-65	241.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi,374YD@32061|Chloroflexia	32061|Chloroflexia	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
CMS3_k127_7633082_1	926569.ANT_13300	1.563e-131	437.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
CMS3_k127_7633082_2	984262.SGRA_4042	6.505e-95	325.0	COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia	976|Bacteroidetes	S	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
CMS3_k127_763777_0	251221.35211511	1.368e-39	167.0	COG4166@1|root,COG4166@2|Bacteria,1GR16@1117|Cyanobacteria	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS3_k127_773172_1	1499967.BAYZ01000196_gene3072	6.224e-30	125.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	AAA_31,Patatin,cNMP_binding
CMS3_k127_773172_3	1423321.AS29_16885	4.419e-09	62.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus	91061|Bacilli	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
CMS3_k127_773172_2	383372.Rcas_1195	1.318e-24	108.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
CMS3_k127_773172_0	243231.GSU1223	6.38e-56	206.0	29FVD@1|root,302T2@2|Bacteria,1RKWC@1224|Proteobacteria,42TAZ@68525|delta/epsilon subdivisions,2WP8E@28221|Deltaproteobacteria,43T6K@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_78306_5	926569.ANT_11560	1.215e-55	209.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_78306_10	547045.NEISICOT_01541	2.332e-08	68.0	COG3307@1|root,COG3307@2|Bacteria,1MYWJ@1224|Proteobacteria,2VKZA@28216|Betaproteobacteria,2KQCK@206351|Neisseriales	206351|Neisseriales	M	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
CMS3_k127_78306_1	926569.ANT_26880	2.292e-88	311.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_78306_7	748280.NH8B_2364	9.452e-49	194.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,2VQB3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_78306_4	525904.Tter_0233	9.581e-63	228.0	COG2227@1|root,COG2227@2|Bacteria,2NQ8I@2323|unclassified Bacteria	2|Bacteria	H	Methyltransferase domain	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_78306_3	1128421.JAGA01000003_gene3564	3.672e-66	233.0	COG1216@1|root,COG1216@2|Bacteria,2NNYJ@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_78306_2	1313172.YM304_07060	2.763e-70	248.0	COG0189@1|root,COG0189@2|Bacteria,2HGGM@201174|Actinobacteria,4CNDT@84992|Acidimicrobiia	84992|Acidimicrobiia	HJ	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
CMS3_k127_78306_9	926569.ANT_01420	2.265e-21	107.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_01420|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_78306_0	926569.ANT_31100	2.26e-115	397.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_78306_8	383372.Rcas_2813	1.218e-31	130.0	COG1716@1|root,COG4385@1|root,COG1716@2|Bacteria,COG4385@2|Bacteria,2G7Z7@200795|Chloroflexi	200795|Chloroflexi	T	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Tail_P2_I
CMS3_k127_78379_0	502025.Hoch_0382	7.054e-152	490.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_78379_1	1541065.JRFE01000015_gene416	1.017e-86	298.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1G0GR@1117|Cyanobacteria,3VI61@52604|Pleurocapsales	1117|Cyanobacteria	E	Glycine cleavage system T protein	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS3_k127_792637_0	555079.Toce_2001	3.678e-192	608.0	COG2403@1|root,COG2403@2|Bacteria,1TPZD@1239|Firmicutes,24E2D@186801|Clostridia,42HSE@68295|Thermoanaerobacterales	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
CMS3_k127_792661_1	926569.ANT_22150	3.148e-77	261.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_792661_5	1223543.GP2_015_00070	1.9e-19	93.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,4GDV2@85026|Gordoniaceae	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS3_k127_792661_3	1121934.AUDX01000021_gene1677	7.858e-23	103.0	COG2009@1|root,COG2009@2|Bacteria,2IKU7@201174|Actinobacteria,4FP54@85023|Microbacteriaceae	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS3_k127_792661_7	1380391.JIAS01000015_gene192	1.707e-16	84.0	COG0745@1|root,COG0745@2|Bacteria,1MZ8W@1224|Proteobacteria,2U9PK@28211|Alphaproteobacteria,2JTJJ@204441|Rhodospirillales	204441|Rhodospirillales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_792661_10	1125700.HMPREF9195_01495	0.0002641	51.0	COG0693@1|root,COG0693@2|Bacteria,2J8IJ@203691|Spirochaetes	203691|Spirochaetes	S	TIGRFAM DJ-1 family protein	thiJ	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS3_k127_792661_4	316274.Haur_1112	7.038e-22	110.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	ko:K16247	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,NB-ARC,TPR_12,TPR_7
CMS3_k127_792661_9	1121272.KB903249_gene1997	9.91e-05	54.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DBE3@85008|Micromonosporales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
CMS3_k127_792661_6	1128421.JAGA01000002_gene684	7.363e-19	98.0	2E48V@1|root,32Z4P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_792661_0	926569.ANT_01680	1.245e-188	605.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
CMS3_k127_792661_2	926569.ANT_01690	5.4e-59	212.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS3_k127_792661_8	926550.CLDAP_06850	3.55e-05	46.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_799092_1	926550.CLDAP_38470	4.309e-102	340.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS3_k127_799092_0	316274.Haur_4761	1.054e-129	422.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi,376RG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_806142_0	644966.Tmar_1720	1.177e-112	376.0	COG1139@1|root,COG1556@1|root,COG1139@2|Bacteria,COG1556@2|Bacteria,1TREQ@1239|Firmicutes,24BXS@186801|Clostridia	186801|Clostridia	C	Iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
CMS3_k127_806142_3	935840.JAEQ01000007_gene3828	2.05e-67	237.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,43JAC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
CMS3_k127_806142_4	702113.PP1Y_AT8041	1.926e-54	204.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2K23Q@204457|Sphingomonadales	204457|Sphingomonadales	M	NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_806142_5	1382356.JQMP01000004_gene417	2.977e-28	130.0	COG5479@1|root,COG5479@2|Bacteria,2GBGV@200795|Chloroflexi,27ZD6@189775|Thermomicrobia	189775|Thermomicrobia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS3_k127_806142_2	266117.Rxyl_2810	3.953e-69	254.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS3_k127_806142_1	926569.ANT_08740	8.889e-86	289.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS3_k127_837647_0	1499967.BAYZ01000108_gene2206	3.332e-82	296.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
CMS3_k127_837647_1	9365.XP_007538289.1	1.446e-20	104.0	KOG4287@1|root,KOG4287@2759|Eukaryota,38W7Q@33154|Opisthokonta,3B9FY@33208|Metazoa,3CSKJ@33213|Bilateria,48AY5@7711|Chordata,490VV@7742|Vertebrata,3J3GX@40674|Mammalia	33208|Metazoa	M	protein depalmitoleylation	NOTUM	GO:0003002,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006505,GO:0006507,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0007389,GO:0007399,GO:0007444,GO:0007447,GO:0007450,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009790,GO:0009792,GO:0009888,GO:0009952,GO:0009953,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0012505,GO:0016298,GO:0016787,GO:0016788,GO:0019538,GO:0019637,GO:0021532,GO:0021915,GO:0023051,GO:0023057,GO:0030111,GO:0030163,GO:0030178,GO:0031974,GO:0032501,GO:0032502,GO:0035220,GO:0035222,GO:0035295,GO:0035601,GO:0036211,GO:0042157,GO:0042159,GO:0042578,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046486,GO:0046488,GO:0048070,GO:0048073,GO:0048076,GO:0048190,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0052689,GO:0060429,GO:0060828,GO:0065007,GO:0070013,GO:0071704,GO:0090090,GO:0098732,GO:1901135,GO:1901564,GO:1901565,GO:1901575,GO:1903509,GO:1990697,GO:1990699	3.1.1.98	ko:K19882	ko04310,map04310	-	R11202	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	PAE
CMS3_k127_837647_2	1211814.CAPG01000092_gene4229	7.225e-06	49.0	29S0J@1|root,30D4W@2|Bacteria,1UAUR@1239|Firmicutes,4IM7J@91061|Bacilli,1ZJEQ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_844934_4	1123508.JH636451_gene6011	8.544e-05	47.0	2DT8B@1|root,33J4Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_844934_1	1120949.KB903339_gene7842	1.512e-94	321.0	COG0604@1|root,COG0604@2|Bacteria,2HWXG@201174|Actinobacteria,4D92G@85008|Micromonosporales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_844934_2	485913.Krac_5692	7.02e-41	160.0	COG1309@1|root,COG1309@2|Bacteria,2G8V4@200795|Chloroflexi	485913.Krac_5692|-	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_844934_0	36809.MAB_1858	9.076e-106	350.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria,233EU@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0050896,GO:0051179,GO:0051234,GO:0055085	-	ko:K16907	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_844934_3	293826.Amet_1482	2.35e-05	53.0	COG1668@1|root,COG1668@2|Bacteria,1V2WV@1239|Firmicutes,24IFP@186801|Clostridia,36MHW@31979|Clostridiaceae	186801|Clostridia	CP	transmembrane transport	-	-	-	ko:K16906	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	-
CMS3_k127_848013_1	365528.KB891137_gene379	8.348e-06	58.0	COG1361@1|root,COG4625@1|root,COG4719@1|root,COG1361@2|Bacteria,COG4625@2|Bacteria,COG4719@2|Bacteria,2I8F1@201174|Actinobacteria	201174|Actinobacteria	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
CMS3_k127_848013_0	765420.OSCT_1178	1.01e-12	81.0	COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,376E7@32061|Chloroflexia	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_849332_0	1047013.AQSP01000140_gene2494	3.361e-31	143.0	COG2234@1|root,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_860381_6	1123388.AQWU01000062_gene2179	1.361e-07	61.0	COG0739@1|root,COG0739@2|Bacteria,1WJ1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
CMS3_k127_860381_3	926569.ANT_22530	8.65e-33	136.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
CMS3_k127_860381_1	765420.OSCT_2689	1.141e-55	206.0	COG4632@1|root,COG4632@2|Bacteria,2G8RE@200795|Chloroflexi,375J8@32061|Chloroflexia	32061|Chloroflexia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
CMS3_k127_860381_5	398527.Bphyt_2741	4.304e-17	88.0	COG2124@1|root,COG4638@1|root,COG2124@2|Bacteria,COG4638@2|Bacteria,1MV75@1224|Proteobacteria,2VIRM@28216|Betaproteobacteria,1K55M@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,p450
CMS3_k127_860381_0	1366050.N234_16785	1.046e-114	381.0	COG2124@1|root,COG2146@1|root,COG2124@2|Bacteria,COG2146@2|Bacteria,1MV75@1224|Proteobacteria,2VIRM@28216|Betaproteobacteria,1K55M@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,p450
CMS3_k127_860381_4	938293.CAJU020000016_gene1705	1.239e-30	124.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,22HNF@1570339|Peptoniphilaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS3_k127_860381_2	1123371.ATXH01000027_gene159	8.05e-33	128.0	COG0211@1|root,COG0211@2|Bacteria,2GI1D@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS3_k127_865175_4	926569.ANT_15670	1.133e-50	201.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_865175_10	1144275.COCOR_03426	1.839e-05	57.0	COG0222@1|root,COG0222@2|Bacteria	2|Bacteria	J	mitochondrial gene expression	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS3_k127_865175_9	8010.XP_010897500.1	1.098e-10	74.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38EA3@33154|Opisthokonta,3BFJH@33208|Metazoa,3CRTV@33213|Bilateria,47YXB@7711|Chordata,48WB8@7742|Vertebrata,4A0TT@7898|Actinopterygii	33208|Metazoa	O	Tripartite motif-containing	TRIM2	GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008092,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010033,GO:0010941,GO:0016567,GO:0016740,GO:0017022,GO:0019538,GO:0019787,GO:0032446,GO:0034097,GO:0036211,GO:0042221,GO:0042981,GO:0043067,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043523,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0061630,GO:0061659,GO:0065007,GO:0070647,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0140096,GO:1901214,GO:1901564,GO:1990823,GO:1990830	-	ko:K11997	-	-	-	-	ko00000,ko04121	-	-	-	Filamin,NHL,zf-B_box,zf-RING_UBOX
CMS3_k127_865175_8	1192034.CAP_2854	1.289e-12	73.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CW5@68525|delta/epsilon subdivisions,2X845@28221|Deltaproteobacteria,2Z3KI@29|Myxococcales	28221|Deltaproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HisKA,PAS,Response_reg
CMS3_k127_865175_0	309801.trd_A0613	4.46e-111	371.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi,27YZB@189775|Thermomicrobia	189775|Thermomicrobia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS3_k127_865175_7	1128421.JAGA01000003_gene3187	9.46e-15	84.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_865175_3	696281.Desru_2712	2.477e-69	245.0	COG0730@1|root,COG0730@2|Bacteria,1UI7C@1239|Firmicutes,24DK7@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_865175_1	357808.RoseRS_3061	3.976e-109	380.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
CMS3_k127_865175_5	404380.Gbem_1954	9.673e-50	182.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42UWE@68525|delta/epsilon subdivisions,2WQ57@28221|Deltaproteobacteria,43V1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_865175_2	443143.GM18_2270	1.556e-106	370.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
CMS3_k127_865175_6	67281.JNZZ01000002_gene2646	2.836e-24	106.0	COG2124@1|root,COG2124@2|Bacteria,2GK4Z@201174|Actinobacteria,41CKN@629295|Streptomyces griseus group	201174|Actinobacteria	C	Cytochrome P450	-	-	-	ko:K21164	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	p450
CMS3_k127_871906_0	1521187.JPIM01000019_gene378	7.944e-36	138.0	COG2343@1|root,COG2343@2|Bacteria,2G79F@200795|Chloroflexi,377I0@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS3_k127_871906_2	1026882.MAMP_00958	1.223e-16	88.0	COG0801@1|root,COG0801@2|Bacteria,1NKUM@1224|Proteobacteria,1SGMD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS3_k127_871906_1	1499967.BAYZ01000145_gene6206	4.403e-32	132.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS3_k127_871906_3	1206735.BAGG01000124_gene5390	1.352e-14	83.0	28HGI@1|root,2Z7SC@2|Bacteria,2GKHQ@201174|Actinobacteria,4FV04@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_877833_0	1121439.dsat_2229	1.206e-229	717.0	COG0031@1|root,COG0031@2|Bacteria,1QQKZ@1224|Proteobacteria,42PVJ@68525|delta/epsilon subdivisions,2WKKY@28221|Deltaproteobacteria,2MEAE@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS3_k127_87986_11	404589.Anae109_2126	4.886e-28	120.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42V72@68525|delta/epsilon subdivisions,2WRHE@28221|Deltaproteobacteria,2Z1JS@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_87986_13	1403313.AXBR01000014_gene2201	0.0005076	46.0	2BTFW@1|root,32NN5@2|Bacteria,1UB53@1239|Firmicutes,4IMHN@91061|Bacilli,1ZK6C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_87986_6	926569.ANT_08910	2.729e-81	289.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi	200795|Chloroflexi	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
CMS3_k127_87986_12	932678.THERU_05545	0.0002817	44.0	COG0115@1|root,COG0115@2|Bacteria,2G4FA@200783|Aquificae	200783|Aquificae	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_87986_5	926569.ANT_06790	3.358e-84	287.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_87986_4	926569.ANT_06780	5.888e-85	284.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
CMS3_k127_87986_7	926569.ANT_06770	7.625e-60	217.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_87986_9	383372.Rcas_0802	1.66e-57	208.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi,375HS@32061|Chloroflexia	32061|Chloroflexia	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
CMS3_k127_87986_1	926569.ANT_06750	3.227e-143	466.0	COG1207@1|root,COG1207@2|Bacteria,2G7KV@200795|Chloroflexi	200795|Chloroflexi	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS3_k127_87986_2	767817.Desgi_0316	5.904e-118	390.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,260YM@186807|Peptococcaceae	186801|Clostridia	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
CMS3_k127_87986_3	926569.ANT_06590	1.064e-103	346.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS3_k127_87986_0	926569.ANT_06600	4.581e-153	518.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_87986_10	926569.ANT_06610	1.711e-35	139.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_87986_8	926569.ANT_06620	8.754e-58	211.0	COG0596@1|root,COG0596@2|Bacteria,2G8RI@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_88039_0	926569.ANT_04530	3.455e-272	850.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
CMS3_k127_88039_1	926550.CLDAP_05010	3.795e-103	348.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_883821_1	765420.OSCT_2504	5.418e-48	184.0	COG0454@1|root,COG0456@2|Bacteria,2G8DV@200795|Chloroflexi,377HZ@32061|Chloroflexia	32061|Chloroflexia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_883821_0	479432.Sros_0608	1.044e-82	282.0	COG5395@1|root,COG5395@2|Bacteria,2IHVI@201174|Actinobacteria,4EJNA@85012|Streptosporangiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
CMS3_k127_891092_1	1157490.EL26_17985	9.163e-94	316.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,2783K@186823|Alicyclobacillaceae	91061|Bacilli	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS3_k127_891092_0	926550.CLDAP_34520	4.429e-116	383.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_894895_2	1537917.JU82_03300	1.535e-20	94.0	COG3012@1|root,COG3012@2|Bacteria,1Q5V3@1224|Proteobacteria,42UFW@68525|delta/epsilon subdivisions,2YPTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
CMS3_k127_894895_0	1501230.ET33_15875	6.478e-80	277.0	COG3386@1|root,COG3386@2|Bacteria,1V1TK@1239|Firmicutes,4HG0A@91061|Bacilli,26S9U@186822|Paenibacillaceae	91061|Bacilli	G	SMP-30 Gluconolaconase LRE domain protein	yvrE	GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
CMS3_k127_894895_1	926569.ANT_26080	1.474e-33	147.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_901402_0	926550.CLDAP_13780	2.592e-83	314.0	COG2311@1|root,COG2311@2|Bacteria,2G8B7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CMS3_k127_901402_1	1385515.N791_06200	9.948e-28	132.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,1X4D8@135614|Xanthomonadales	135614|Xanthomonadales	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_913525_1	926550.CLDAP_00060	4.105e-61	217.0	COG0265@1|root,COG0265@2|Bacteria,2G6I9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_913525_2	1128421.JAGA01000002_gene1677	7.101e-29	123.0	COG0265@1|root,COG0265@2|Bacteria,2NR4X@2323|unclassified Bacteria	2|Bacteria	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_913525_0	926569.ANT_24710	6.551e-87	292.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS3_k127_918371_13	398512.JQKC01000001_gene2421	1.451e-13	72.0	COG3809@1|root,COG3809@2|Bacteria,1W4K3@1239|Firmicutes,257J6@186801|Clostridia,3WR0S@541000|Ruminococcaceae	186801|Clostridia	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_918371_3	580332.Slit_2268	4.061e-57	203.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,2WAUM@28216|Betaproteobacteria,44WGD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS3_k127_918371_15	1157490.EL26_02350	1.583e-09	68.0	COG1073@1|root,COG1073@2|Bacteria,1V84C@1239|Firmicutes,4HIW2@91061|Bacilli	91061|Bacilli	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_918371_12	1238182.C882_1865	1.748e-15	81.0	COG0454@1|root,COG0456@2|Bacteria,1N6QA@1224|Proteobacteria,2UFGS@28211|Alphaproteobacteria,2JUES@204441|Rhodospirillales	204441|Rhodospirillales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_918371_14	1408418.JNJH01000049_gene171	6.438e-10	64.0	COG0454@1|root,COG0456@2|Bacteria,1N6QA@1224|Proteobacteria	1224|Proteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS3_k127_918371_5	306281.AJLK01000072_gene656	1.593e-44	172.0	COG3315@1|root,COG3315@2|Bacteria,1G5YU@1117|Cyanobacteria	1117|Cyanobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_918371_4	373994.Riv7116_1807	8.993e-52	195.0	COG0596@1|root,COG0596@2|Bacteria,1GJMM@1117|Cyanobacteria,1HSGW@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_918371_8	926560.KE387023_gene2483	1.728e-24	108.0	293K9@1|root,2ZR28@2|Bacteria	2|Bacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS3_k127_918371_1	1123020.AUIE01000023_gene5005	7.927e-133	436.0	COG0454@1|root,COG0454@2|Bacteria,1MVVG@1224|Proteobacteria,1RQ5J@1236|Gammaproteobacteria,1YIF9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_918371_0	1123020.AUIE01000023_gene5004	6.611e-164	522.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,1RPKM@1236|Gammaproteobacteria,1YHCZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
CMS3_k127_918371_16	388399.SSE37_02360	0.000778	46.0	2EFRX@1|root,339HW@2|Bacteria,1NEME@1224|Proteobacteria,2UFXW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_918371_10	756272.Plabr_0693	3.811e-20	102.0	2ED92@1|root,3375I@2|Bacteria,2J41R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_918371_7	1158607.UAU_02539	2.082e-32	136.0	COG0739@1|root,COG0739@2|Bacteria,1UYKB@1239|Firmicutes,4HGXN@91061|Bacilli,4B1NQ@81852|Enterococcaceae	91061|Bacilli	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS3_k127_918371_2	243090.RB6151	3.455e-86	292.0	COG3361@1|root,COG3361@2|Bacteria,2IYZC@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (COG2071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2071
CMS3_k127_918371_6	1382306.JNIM01000001_gene2203	5.255e-34	136.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_918371_9	58123.JOFJ01000007_gene743	1.569e-22	98.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EHK4@85012|Streptosporangiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_918509_1	316274.Haur_0247	1.761e-39	154.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2G8VD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
CMS3_k127_918509_0	1336249.JADW01000009_gene1560	9.304e-69	245.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,2U3N3@28211|Alphaproteobacteria,4B738@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_927633_3	926569.ANT_05200	3.944e-16	83.0	COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi	200795|Chloroflexi	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_927633_0	1382306.JNIM01000001_gene1297	2.566e-100	336.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS3_k127_927633_1	485913.Krac_10277	7.311e-30	121.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS3_k127_927633_2	469371.Tbis_2599	1.221e-18	87.0	COG1032@1|root,COG1032@2|Bacteria,2HW71@201174|Actinobacteria,4E7P4@85010|Pseudonocardiales	201174|Actinobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_936984_2	316274.Haur_1672	7.382e-53	197.0	COG0451@1|root,COG0451@2|Bacteria,2GADR@200795|Chloroflexi,375N9@32061|Chloroflexia	32061|Chloroflexia	GM	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_936984_0	316274.Haur_1671	1.896e-100	341.0	COG0204@1|root,COG0204@2|Bacteria,2GACB@200795|Chloroflexi,37578@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_936984_1	1088721.NSU_1615	2.82e-60	215.0	COG1432@1|root,COG1432@2|Bacteria,1RJ15@1224|Proteobacteria,2UCYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
CMS3_k127_936984_3	228405.HNE_0829	2.354e-18	89.0	2B5YT@1|root,31YUV@2|Bacteria,1RF42@1224|Proteobacteria,2U8FC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3088
CMS3_k127_936984_4	582515.KR51_00025510	5.945e-06	49.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS3_k127_941040_1	1035308.AQYY01000001_gene2733	3.889e-49	189.0	2DMU2@1|root,32TPK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_941040_0	211165.AJLN01000120_gene756	7.832e-135	456.0	COG3391@1|root,COG4385@1|root,COG3391@2|Bacteria,COG4385@2|Bacteria,1GJPJ@1117|Cyanobacteria,1JMN0@1189|Stigonemataceae	1117|Cyanobacteria	CO	Tail protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_941040_2	1123320.KB889561_gene4906	1.255e-32	133.0	COG3210@1|root,COG3210@2|Bacteria,2H3VA@201174|Actinobacteria	201174|Actinobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_953562_3	595494.Tola_1240	1.826e-10	75.0	COG5617@1|root,COG5617@2|Bacteria,1RJY5@1224|Proteobacteria,1SE0V@1236|Gammaproteobacteria,1Y5JR@135624|Aeromonadales	135624|Aeromonadales	S	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
CMS3_k127_953562_2	926550.CLDAP_04460	2.419e-13	84.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_953562_1	671143.DAMO_0096	1.545e-54	205.0	COG2232@1|root,COG2232@2|Bacteria	2|Bacteria	V	ATP-grasp domain	-	-	3.5.4.27	ko:K01499,ko:K06913	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03464	RC01870	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
CMS3_k127_953562_0	926560.KE387023_gene3595	4.642e-69	244.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS3_k127_95367_2	406124.ACPC01000030_gene1838	1.294e-19	91.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,1ZBFC@1386|Bacillus	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS3_k127_95367_1	1463821.JOGR01000001_gene1376	3.324e-59	214.0	COG2227@1|root,COG2227@2|Bacteria,2I8GJ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_95367_0	358681.BBR47_24220	6.012e-74	271.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,26QG6@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_960331_13	1298863.AUEP01000008_gene1319	4.232e-11	64.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
CMS3_k127_960331_11	82654.Pse7367_3227	7.697e-27	114.0	COG0745@1|root,COG0745@2|Bacteria,1G8I2@1117|Cyanobacteria,1HCIH@1150|Oscillatoriales	1117|Cyanobacteria	KT	PFAM Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_960331_1	1128421.JAGA01000002_gene1337	1.455e-94	323.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	2.1.1.242,2.1.1.303,2.1.1.319	ko:K11434,ko:K15984,ko:K20421	ko01059,ko01130,ko04068,ko04922,map01059,map01130,map04068,map04922	M00830	R10963,R11216,R11217,R11219	RC00003,RC00392,RC02120,RC03388,RC03390	ko00000,ko00001,ko00002,ko01000,ko03009,ko03036	-	-	-	DOT1,Methyltransf_21,Methyltransf_25
CMS3_k127_960331_10	1385935.N836_15200	2.573e-27	121.0	COG2887@1|root,COG2887@2|Bacteria,1G42T@1117|Cyanobacteria,1H9XC@1150|Oscillatoriales	1117|Cyanobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CMS3_k127_960331_0	316274.Haur_2758	2.083e-99	330.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
CMS3_k127_960331_3	926550.CLDAP_10830	2.007e-75	263.0	COG0765@1|root,COG0765@2|Bacteria,2G6IJ@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS3_k127_960331_5	765420.OSCT_1428	9.511e-72	252.0	COG0834@1|root,COG0834@2|Bacteria,2G6HE@200795|Chloroflexi,376SS@32061|Chloroflexia	32061|Chloroflexia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS3_k127_960331_7	926550.CLDAP_19610	4.67e-56	214.0	COG0589@1|root,COG0589@2|Bacteria,2GBJZ@200795|Chloroflexi	200795|Chloroflexi	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_960331_2	1123229.AUBC01000029_gene3528	1.314e-90	307.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
CMS3_k127_960331_4	926569.ANT_04130	1.218e-73	267.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS3_k127_960331_12	288705.RSal33209_2580	3.709e-15	89.0	2DBIT@1|root,2Z9GU@2|Bacteria,2GN03@201174|Actinobacteria,1WCDR@1268|Micrococcaceae	201174|Actinobacteria	S	Carotene biosynthesis associated membrane protein	mptB	-	-	ko:K14337,ko:K14339	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	GT87
CMS3_k127_960331_9	926550.CLDAP_11940	2.215e-44	186.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_960331_6	316274.Haur_2146	1.535e-70	249.0	28XHJ@1|root,2ZJEY@2|Bacteria	2|Bacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	ko:K15911,ko:K22313	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS3_k127_960331_8	316274.Haur_2145	1.382e-53	197.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_963272_0	926569.ANT_11840	2.126e-50	182.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_963272_1	1379281.AVAG01000018_gene1031	6.142e-07	62.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_9673_0	926569.ANT_12840	1.042e-181	601.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_9673_1	926569.ANT_24730	2.53e-72	250.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi	200795|Chloroflexi	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_977149_2	314230.DSM3645_22024	6.686e-44	169.0	COG0518@1|root,COG0518@2|Bacteria,2J0QU@203682|Planctomycetes	203682|Planctomycetes	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
CMS3_k127_977149_0	452637.Oter_2875	5.81e-62	222.0	COG0672@1|root,COG0672@2|Bacteria,46XX5@74201|Verrucomicrobia,3K8IC@414999|Opitutae	414999|Opitutae	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
CMS3_k127_977149_1	1123389.ATXJ01000047_gene435	3.79e-55	204.0	COG1277@1|root,COG1277@2|Bacteria,1WN4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS3_k127_977865_8	1206730.BAGA01000074_gene1865	2.013e-21	96.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4FZ9I@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
CMS3_k127_977865_5	1089551.KE386572_gene2233	2.592e-85	289.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,4BSGF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_977865_6	1385935.N836_26360	6.07e-60	226.0	COG1512@1|root,COG1512@2|Bacteria,1G221@1117|Cyanobacteria,1H9Z2@1150|Oscillatoriales	1117|Cyanobacteria	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS3_k127_977865_1	439235.Dalk_2094	2.222e-130	444.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria,2MPUY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS3_k127_977865_10	266117.Rxyl_1807	2.936e-17	91.0	COG1475@1|root,COG1475@2|Bacteria,2IAI6@201174|Actinobacteria,4CQE8@84995|Rubrobacteria	84995|Rubrobacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
CMS3_k127_977865_4	324602.Caur_0381	3.649e-101	339.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
CMS3_k127_977865_7	345341.KUTG_07933	7.951e-56	213.0	2E8I5@1|root,332W5@2|Bacteria,2GRF8@201174|Actinobacteria,4E68Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_977865_3	1394178.AWOO02000098_gene8149	1.585e-114	391.0	COG1252@1|root,COG1252@2|Bacteria,2GJFE@201174|Actinobacteria	201174|Actinobacteria	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_977865_0	266117.Rxyl_2557	4.273e-137	452.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria,4CPP8@84995|Rubrobacteria	84995|Rubrobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_977865_2	1128421.JAGA01000003_gene3460	4.935e-118	392.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
CMS3_k127_977865_9	1121382.JQKG01000006_gene3396	2.551e-18	89.0	2DUWA@1|root,33SPG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_983720_0	926550.CLDAP_34270	2.38e-80	274.0	COG1482@1|root,COG1482@2|Bacteria,2G6I2@200795|Chloroflexi	200795|Chloroflexi	G	PFAM mannose-6-phosphate isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS3_k127_983720_3	342113.DM82_5167	1.222e-09	59.0	COG0053@1|root,COG0053@2|Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,Nitro_FeMo-Co,ZT_dimer
CMS3_k127_983720_1	326427.Cagg_3676	3.534e-23	103.0	COG0789@1|root,COG0789@2|Bacteria,2G9AM@200795|Chloroflexi,377U8@32061|Chloroflexia	32061|Chloroflexia	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS3_k127_983720_2	765420.OSCT_0917	1.153e-17	96.0	COG1874@1|root,COG1874@2|Bacteria,2GBMG@200795|Chloroflexi,376H5@32061|Chloroflexia	32061|Chloroflexia	G	Flagellar filament outer layer protein Flaa	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_cc
CMS3_k127_985246_3	311424.DhcVS_1083	3.111e-22	102.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_985246_0	1121405.dsmv_1320	0.0	1292.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_985246_2	926550.CLDAP_11630	6.628e-64	228.0	COG2452@1|root,COG4936@1|root,COG2452@2|Bacteria,COG4936@2|Bacteria	2|Bacteria	KT	Sensory domain found in PocR	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HTH_17,PocR
CMS3_k127_985246_1	880073.Calab_2460	1.535e-176	562.0	COG0446@1|root,COG0446@2|Bacteria,2NPPU@2323|unclassified Bacteria	2|Bacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DsrC,Pyr_redox_2
CMS3_k127_995560_4	1089549.AZUQ01000001_gene1559	1.301e-35	136.0	COG1193@1|root,COG1193@2|Bacteria,2I4QA@201174|Actinobacteria,4EYUQ@85014|Glycomycetales	201174|Actinobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS3_k127_995560_1	521011.Mpal_1345	4.862e-83	301.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
CMS3_k127_995560_5	526227.Mesil_0256	1.477e-24	107.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
CMS3_k127_995560_3	926560.KE387027_gene262	7.153e-43	168.0	2F64E@1|root,33YNP@2|Bacteria	2|Bacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,MDMPI_N
CMS3_k127_995560_2	1288484.APCS01000166_gene2746	8.122e-78	269.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria,1WICF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
CMS3_k127_995560_0	1288484.APCS01000166_gene2746	8.203e-115	378.0	COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria,1WICF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
CMS3_k127_995560_6	926550.CLDAP_09520	2.493e-07	54.0	COG1472@1|root,COG1472@2|Bacteria,2G5S5@200795|Chloroflexi	200795|Chloroflexi	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS3_k127_997326_2	869213.JCM21142_41533	1.643e-91	308.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,47MRY@768503|Cytophagia	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS3_k127_997326_3	1120953.AUBH01000001_gene960	5.755e-56	201.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS3_k127_997326_0	1191523.MROS_2210	3.793e-300	935.0	COG0365@1|root,COG0365@2|Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_997326_1	251229.Chro_2356	1.684e-92	312.0	COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,3VMQS@52604|Pleurocapsales	1117|Cyanobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS3_k127_997326_4	203122.Sde_2868	5.465e-23	106.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria,1SAFU@1236|Gammaproteobacteria,46DJS@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
## 6396 queries scanned
## Total time (seconds): 126.36391258239746
## Rate: 50.62 q/s