## Mon Nov 11 04:34:44 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS3_bin.81.fa -m mmseqs --itype genome -o CMS3_bin.81 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS3_bin.81 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS3_k127_1000962_0	1123508.JH636439_gene715	6.176e-06	59.0	COG1331@1|root,COG1331@2|Bacteria,2J18M@203682|Planctomycetes	203682|Planctomycetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CMS3_k127_1007975_1	85643.Tmz1t_1473	9.077e-153	509.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
CMS3_k127_1007975_0	575540.Isop_3573	7.181e-241	794.0	2DUKG@1|root,33R4D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1007975_6	575540.Isop_3572	1.073e-43	166.0	2ECWJ@1|root,336TU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1007975_5	1396141.BATP01000040_gene2148	3.499e-79	284.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_1007975_3	575540.Isop_3570	1.98e-102	349.0	COG2304@1|root,COG2304@2|Bacteria,2IXVS@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_1007975_7	575540.Isop_3569	9.451e-43	179.0	2BXEQ@1|root,33IN8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1007975_4	575540.Isop_3568	2.259e-102	341.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_1007975_2	575540.Isop_3567	4.162e-145	469.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	2|Bacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_1007975_8	98439.AJLL01000063_gene1117	3.532e-24	120.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1G04D@1117|Cyanobacteria,1JKHR@1189|Stigonemataceae	1117|Cyanobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
CMS3_k127_1007975_9	1120949.KB903294_gene4037	6.929e-18	96.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	lpqD	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS3_k127_1015104_0	471852.Tcur_3153	2.313e-181	590.0	COG1357@1|root,COG1409@1|root,COG2319@1|root,COG5635@1|root,COG1357@2|Bacteria,COG1409@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT,Pentapeptide,TIR_2,Trypsin_2,WD40
CMS3_k127_1015104_4	309807.SRU_1894	1.017e-55	221.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1FJEG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,Peptidase_M1
CMS3_k127_1015104_3	1123242.JH636438_gene5844	3.941e-63	235.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_1015104_1	521674.Plim_2376	1.179e-104	358.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_1015104_6	204669.Acid345_1569	8.417e-07	60.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS3_k127_1015104_2	521674.Plim_3672	6.594e-93	320.0	2BZ6M@1|root,2Z7HW@2|Bacteria,2IXV4@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_1015104_5	756272.Plabr_2893	4.091e-19	100.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
CMS3_k127_1020375_0	247490.KSU1_C1563	6.567e-145	499.0	COG1674@1|root,COG1674@2|Bacteria,2IXHF@203682|Planctomycetes	203682|Planctomycetes	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_1020375_7	1123389.ATXJ01000002_gene1428	7.736e-43	166.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_1020375_5	1232437.KL662020_gene699	2.582e-53	210.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_1020375_6	344747.PM8797T_18891	4.753e-50	201.0	COG0845@1|root,COG0845@2|Bacteria,2IXP7@203682|Planctomycetes	203682|Planctomycetes	M	COG0845 Membrane-fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,HlyD_3,HlyD_D23
CMS3_k127_1020375_4	351160.RCIX1294	1.287e-72	254.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,2N9GV@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1020375_3	886293.Sinac_5745	3.461e-93	320.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_1020375_1	1356852.N008_13820	4.399e-129	432.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS3_k127_1020375_8	595460.RRSWK_04777	5.481e-42	161.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_1020375_2	1267533.KB906733_gene3472	1.356e-99	349.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_1025816_2	391612.CY0110_12217	7.426e-05	52.0	COG3809@1|root,COG3809@2|Bacteria,1G6XN@1117|Cyanobacteria,3KI8N@43988|Cyanothece	1117|Cyanobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
CMS3_k127_1025816_0	530564.Psta_3995	7.275e-59	213.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS3_k127_1025816_1	443143.GM18_3005	1.193e-08	68.0	COG3945@1|root,COG3945@2|Bacteria,1NG3G@1224|Proteobacteria,42WHU@68525|delta/epsilon subdivisions,2WRK5@28221|Deltaproteobacteria,43UTP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_1030982_0	234267.Acid_2676	1.599e-206	648.0	COG0620@1|root,COG0620@2|Bacteria,3Y8ZA@57723|Acidobacteria	57723|Acidobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_1030982_2	1296415.JACC01000006_gene1510	1.03e-12	73.0	COG3245@1|root,COG3245@2|Bacteria,4PJ3G@976|Bacteroidetes,1IMG7@117743|Flavobacteriia,2YKV3@290174|Aquimarina	976|Bacteroidetes	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1030982_1	1296415.JACC01000006_gene1509	1.175e-69	249.0	COG2960@1|root,COG2960@2|Bacteria,4NI9S@976|Bacteroidetes,1ICN0@117743|Flavobacteriia,2YKN6@290174|Aquimarina	976|Bacteroidetes	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1035256_7	886293.Sinac_1523	3.974e-148	491.0	COG1164@1|root,COG1164@2|Bacteria,2IYTJ@203682|Planctomycetes	203682|Planctomycetes	E	TIGRFAM oligoendopeptidase, M3 family	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS3_k127_1035256_4	595460.RRSWK_06726	1.216e-169	550.0	COG0372@1|root,COG0372@2|Bacteria,2IYFN@203682|Planctomycetes	203682|Planctomycetes	H	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_1035256_9	404589.Anae109_1129	8.093e-126	431.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2WMB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS3_k127_1035256_21	649638.Trad_0227	1.721e-51	207.0	COG0181@1|root,COG0181@2|Bacteria,1WM2C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS3_k127_1035256_27	471852.Tcur_4440	3.725e-32	140.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4EH7H@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_1035256_31	2074.JNYD01000011_gene140	8.622e-08	60.0	COG0589@1|root,COG2905@1|root,COG0589@2|Bacteria,COG2905@2|Bacteria,2I3QN@201174|Actinobacteria,4EF69@85010|Pseudonocardiales	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS,Usp
CMS3_k127_1035256_5	1121440.AUMA01000001_gene46	9.895e-161	519.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2WJU0@28221|Deltaproteobacteria,2M939@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS3_k127_1035256_3	671143.DAMO_0393	6.459e-198	640.0	COG0507@1|root,COG0507@2|Bacteria,2NNQY@2323|unclassified Bacteria	2|Bacteria	L	Helix-hairpin-helix containing domain	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS3_k127_1035256_36	877420.ATVW01000001_gene2103	0.0007176	49.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,27PJR@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS3_k127_1035256_23	420246.GTNG_1003	1.132e-49	192.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1WFGB@129337|Geobacillus	91061|Bacilli	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_1035256_34	1122925.KB895376_gene693	0.0005519	53.0	28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,26U9P@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1035256_13	195250.CM001776_gene1384	4.599e-97	332.0	COG4398@1|root,COG4398@2|Bacteria,1G0TB@1117|Cyanobacteria,1GYRY@1129|Synechococcus	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CMS3_k127_1035256_16	330214.NIDE2086	3.275e-83	316.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_1035256_28	500153.JOEK01000013_gene1766	2.279e-13	85.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS3_k127_1035256_33	794903.OPIT5_21345	0.0002731	53.0	2EMGZ@1|root,33F5K@2|Bacteria,46TB4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1035256_22	871968.DESME_14345	2.298e-50	196.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase, group 2 family protein	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
CMS3_k127_1035256_35	100226.SCO0391	0.000589	51.0	COG0297@1|root,COG0297@2|Bacteria,2I30C@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1035256_14	215803.DB30_0394	7.496e-90	304.0	COG0583@1|root,COG0583@2|Bacteria,1PPRQ@1224|Proteobacteria,433YA@68525|delta/epsilon subdivisions,2X421@28221|Deltaproteobacteria,2YY0E@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_1035256_0	330214.NIDE1185	0.0	1146.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3J17I@40117|Nitrospirae	40117|Nitrospirae	I	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20,6.2.1.3	ko:K01897,ko:K05939	ko00061,ko00071,ko00564,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00564,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R01406,R04864	RC00004,RC00014,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,Acyltransferase
CMS3_k127_1035256_15	177437.HRM2_42890	1.611e-84	288.0	COG2126@1|root,COG2126@2|Bacteria,1MXCS@1224|Proteobacteria,42NVQ@68525|delta/epsilon subdivisions,2WJFT@28221|Deltaproteobacteria,2MHX5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS3_k127_1035256_1	1123248.KB893317_gene4292	1.073e-273	902.0	COG0613@1|root,COG0613@2|Bacteria,4PN3D@976|Bacteroidetes	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1035256_26	1227454.C446_00310	7.445e-41	166.0	COG0438@1|root,arCOG01403@2157|Archaea,2XWAX@28890|Euryarchaeota,23TPP@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1035256_29	998674.ATTE01000001_gene2467	3.975e-13	76.0	COG2383@1|root,COG2383@2|Bacteria,1MZVW@1224|Proteobacteria,1SAW6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	FUN14 family	-	-	-	-	-	-	-	-	-	-	-	-	FUN14
CMS3_k127_1035256_8	1123242.JH636434_gene4153	1.758e-128	428.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_1035256_18	324602.Caur_0969	1.799e-73	261.0	COG1131@1|root,COG1131@2|Bacteria,2GAQH@200795|Chloroflexi,3753M@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_1035256_6	243090.RB605	2.592e-153	498.0	COG3119@1|root,COG3119@2|Bacteria,2J1ZQ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_1035256_12	331869.BAL199_15663	3.17e-101	346.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2TU4M@28211|Alphaproteobacteria,4BPY8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	ycaD	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS3_k127_1035256_17	1121859.KB890755_gene1122	3.099e-79	284.0	COG0657@1|root,COG0657@2|Bacteria,4NJ8D@976|Bacteroidetes	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DLH,Lipase_GDSL_2,Peptidase_S9
CMS3_k127_1035256_24	756272.Plabr_4562	1.803e-44	180.0	COG2755@1|root,COG2755@2|Bacteria,2IZUU@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS3_k127_1035256_19	1192034.CAP_5059	1.794e-62	236.0	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
CMS3_k127_1035256_10	1353529.M899_1617	1.107e-115	380.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2MSV0@213481|Bdellovibrionales,2WIY8@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
CMS3_k127_1035256_2	1122939.ATUD01000001_gene577	3.43e-199	669.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1035256_11	886293.Sinac_2761	1.496e-113	404.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_1035256_25	886293.Sinac_7484	3.307e-43	167.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1035256_20	1122621.ATZA01000009_gene289	2.455e-58	211.0	COG1131@1|root,COG1131@2|Bacteria,4NJ0D@976|Bacteroidetes,1IQ6J@117747|Sphingobacteriia	976|Bacteroidetes	V	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1035256_30	1403819.BATR01000007_gene237	1.673e-10	71.0	COG2133@1|root,COG2133@2|Bacteria,46V55@74201|Verrucomicrobia,2IVGJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_1045281_18	189426.PODO_18230	7.668e-09	58.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,26S55@186822|Paenibacillaceae	91061|Bacilli	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_1045281_12	575540.Isop_2609	5.735e-53	197.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_1045281_16	1123253.AUBD01000011_gene2084	2.992e-22	109.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,1SCFM@1236|Gammaproteobacteria,1X7GP@135614|Xanthomonadales	135614|Xanthomonadales	P	protein involved in tolerance to divalent cations	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CMS3_k127_1045281_5	404589.Anae109_3751	1.489e-108	370.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2YTU1@29|Myxococcales	28221|Deltaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS3_k127_1045281_7	357808.RoseRS_4405	1.718e-85	298.0	COG1171@1|root,COG1171@2|Bacteria,2G6ME@200795|Chloroflexi,3776A@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_1045281_0	314230.DSM3645_08196	0.0	1209.0	COG0457@1|root,COG1729@1|root,COG2373@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,TPR_16
CMS3_k127_1045281_20	1210884.HG799464_gene10441	5.453e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,2J0VV@203682|Planctomycetes	203682|Planctomycetes	S	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase
CMS3_k127_1045281_15	234267.Acid_3493	6.98e-23	103.0	COG0457@1|root,COG0457@2|Bacteria,3Y75T@57723|Acidobacteria	57723|Acidobacteria	S	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase,TPR_16
CMS3_k127_1045281_6	243233.MCA2830	2.044e-99	342.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
CMS3_k127_1045281_11	479434.Sthe_1889	7.393e-59	221.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_1045281_3	661478.OP10G_0832	4.006e-157	525.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
CMS3_k127_1045281_1	243090.RB1828	1.624e-253	795.0	COG3540@1|root,COG3540@2|Bacteria,2J1R1@203682|Planctomycetes	203682|Planctomycetes	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1045281_19	1157635.KB892013_gene2182	8.641e-08	64.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria	201174|Actinobacteria	G	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_1045281_4	247634.GPB2148_756	2.564e-109	373.0	COG0535@1|root,COG0535@2|Bacteria,1NEM7@1224|Proteobacteria	1224|Proteobacteria	M	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_1045281_14	194867.ALBQ01000034_gene1036	8.55e-41	160.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,2K17W@204457|Sphingomonadales	204457|Sphingomonadales	P	Molybdenum ABC transporter	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS3_k127_1045281_8	1470591.BW41_02603	1.393e-64	228.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria,2K0AD@204457|Sphingomonadales	204457|Sphingomonadales	P	Molybdate	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS3_k127_1045281_9	1217720.ALOX01000001_gene3401	4.745e-64	243.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,2JQNZ@204441|Rhodospirillales	204441|Rhodospirillales	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
CMS3_k127_1045281_13	331113.SNE_A15280	6.71e-49	186.0	COG4286@1|root,COG4286@2|Bacteria,2JFGF@204428|Chlamydiae	204428|Chlamydiae	S	conserved protein related to MYG1 family	CP_0265	-	-	-	-	-	-	-	-	-	-	-	UPF0160
CMS3_k127_1045281_10	1079460.ATTQ01000033_gene4046	3.068e-61	229.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,4B8PG@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	MA20_00470	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1045281_2	215803.DB30_4063	3.589e-229	728.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS3_k127_1045281_17	883126.HMPREF9710_02757	9.836e-10	59.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,472M9@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS3_k127_1051426_18	882082.SaccyDRAFT_1387	3.577e-36	147.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4DZW7@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_1051426_25	1030157.AFMP01000030_gene3130	6.333e-17	83.0	COG1034@1|root,COG1034@2|Bacteria,1NG4R@1224|Proteobacteria,2UHBG@28211|Alphaproteobacteria,2K7AN@204457|Sphingomonadales	204457|Sphingomonadales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4
CMS3_k127_1051426_11	2002.JOEQ01000002_gene4530	1.729e-82	295.0	COG0446@1|root,COG0446@2|Bacteria,2GJM6@201174|Actinobacteria,4EI5D@85012|Streptosporangiales	201174|Actinobacteria	S	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD,Pyr_redox_2
CMS3_k127_1051426_14	861299.J421_1521	1.058e-54	201.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_1051426_2	867903.ThesuDRAFT_00241	5.133e-179	577.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,3WCFR@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS3_k127_1051426_12	379066.GAU_2854	1.303e-74	276.0	COG2866@1|root,COG2866@2|Bacteria,1ZT9V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_1051426_1	1267534.KB906759_gene1728	7.181e-229	723.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	PFOR_II,POR,POR_N,Transketolase_C
CMS3_k127_1051426_6	1267534.KB906759_gene1729	1.657e-112	370.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	2|Bacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
CMS3_k127_1051426_4	314230.DSM3645_06014	4.325e-147	483.0	COG3119@1|root,COG3119@2|Bacteria,2J24M@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_1051426_15	1380394.JADL01000010_gene4356	1.976e-48	183.0	COG3221@1|root,COG3221@2|Bacteria,1RDG5@1224|Proteobacteria,2U8X7@28211|Alphaproteobacteria,2JZMB@204441|Rhodospirillales	204441|Rhodospirillales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
CMS3_k127_1051426_9	292459.STH2490	4.751e-98	334.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
CMS3_k127_1051426_21	987059.RBXJA2T_15243	4.059e-26	117.0	COG3455@1|root,COG3455@2|Bacteria,1NMWP@1224|Proteobacteria,2VH4H@28216|Betaproteobacteria,1KPGJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Type VI secretion system protein DotU	dotU1	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
CMS3_k127_1051426_8	330214.NIDE1973	1.786e-103	376.0	COG3523@1|root,COG3523@2|Bacteria,3J159@40117|Nitrospirae	40117|Nitrospirae	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
CMS3_k127_1051426_20	1144275.COCOR_03385	6.486e-33	138.0	COG5239@1|root,COG5239@2|Bacteria,1Q2TB@1224|Proteobacteria,438F6@68525|delta/epsilon subdivisions,2X3Q4@28221|Deltaproteobacteria,2YWTR@29|Myxococcales	28221|Deltaproteobacteria	A	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_1051426_7	338963.Pcar_2000	3.434e-106	357.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,43S11@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Protein of unknown function (DUF933)	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS3_k127_1051426_17	883126.HMPREF9710_00736	1.085e-36	160.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2
CMS3_k127_1051426_3	861299.J421_4478	7.071e-156	517.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_1051426_23	886293.Sinac_4659	1.401e-19	104.0	COG1520@1|root,COG1520@2|Bacteria,2IWVC@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_1051426_0	1227454.C446_01773	0.0	1277.0	COG5013@1|root,arCOG01497@2157|Archaea,2XUSJ@28890|Euryarchaeota,23UWV@183963|Halobacteria	183963|Halobacteria	C	Molybdopterin oxidoreductase	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin
CMS3_k127_1051426_5	1158150.KB906246_gene1914	9.815e-147	473.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11
CMS3_k127_1051426_22	1158150.KB906246_gene1913	5.805e-25	122.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh,Nitrate_red_del
CMS3_k127_1051426_24	1379698.RBG1_1C00001G0008	3.053e-17	91.0	COG3381@1|root,COG3381@2|Bacteria	2|Bacteria	S	protein complex oligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
CMS3_k127_1051426_16	1123400.KB904802_gene3217	6.417e-39	160.0	COG3735@1|root,COG3735@2|Bacteria,1RBFT@1224|Proteobacteria	1224|Proteobacteria	S	PFAM GumN family protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS3_k127_1051426_13	391625.PPSIR1_36914	1.111e-64	234.0	COG0434@1|root,COG0434@2|Bacteria,1PI3K@1224|Proteobacteria,435DY@68525|delta/epsilon subdivisions,2X98F@28221|Deltaproteobacteria,2Z2KI@29|Myxococcales	28221|Deltaproteobacteria	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
CMS3_k127_1051426_19	909663.KI867150_gene2181	9.813e-34	143.0	COG0438@1|root,COG0438@2|Bacteria,1N2C6@1224|Proteobacteria,42UQ0@68525|delta/epsilon subdivisions,2WQU7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1051987_6	485918.Cpin_2692	1.161e-12	73.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IR4V@117747|Sphingobacteriia	976|Bacteroidetes	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_1051987_3	886293.Sinac_4679	9.78e-167	544.0	2DBKQ@1|root,2Z9U7@2|Bacteria,2IWVD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1051987_0	1121920.AUAU01000003_gene1185	0.0	1434.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,3Y2JQ@57723|Acidobacteria	57723|Acidobacteria	E	glutamate synthase alpha subunit	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS3_k127_1051987_1	1121015.N789_00810	2.224e-177	570.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1X3PI@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_1051987_2	588932.JHOF01000005_gene2220	6.248e-169	576.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,2KF2D@204458|Caulobacterales	204458|Caulobacterales	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS3_k127_1051987_5	767434.Fraau_3197	1.839e-52	208.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,1X3N1@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS3_k127_1051987_4	1242864.D187_003306	3.108e-119	398.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_1053964_6	1210884.HG799472_gene14862	1.055e-21	100.0	COG0154@1|root,COG0154@2|Bacteria,2IY50@203682|Planctomycetes	203682|Planctomycetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CMS3_k127_1053964_0	314230.DSM3645_11507	3.662e-255	818.0	COG2010@1|root,COG2010@2|Bacteria,2IYQJ@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_1053964_2	314230.DSM3645_11502	2.984e-196	636.0	COG4102@1|root,COG4102@2|Bacteria,2IX70@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_1053964_8	43989.cce_3037	3.46e-07	63.0	2BVDD@1|root,32QTC@2|Bacteria,1GE4T@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1053964_5	886293.Sinac_5718	2.993e-84	313.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CMS3_k127_1053964_1	1403819.BATR01000027_gene884	1.422e-197	647.0	COG2133@1|root,COG2133@2|Bacteria,46UKF@74201|Verrucomicrobia,2IU1Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1053964_3	1123508.JH636439_gene932	2.204e-147	500.0	COG2010@1|root,COG2010@2|Bacteria,2IXIX@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,PA14
CMS3_k127_1053964_4	521674.Plim_1708	1.322e-108	364.0	COG1793@1|root,COG1793@2|Bacteria,2J0I2@203682|Planctomycetes	203682|Planctomycetes	L	secreted glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_1055313_4	886293.Sinac_3618	4.371e-76	287.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_1055313_7	1123053.AUDG01000052_gene1929	2.959e-05	54.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,1S5DM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_1055313_2	215803.DB30_5754	4.741e-93	312.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS3_k127_1055313_0	1384054.N790_13310	4.401e-216	683.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria,1X4BQ@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_1055313_1	886293.Sinac_6651	2.814e-107	385.0	COG2027@1|root,COG2027@2|Bacteria,2IYAC@203682|Planctomycetes	203682|Planctomycetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS3_k127_1055313_3	391625.PPSIR1_08007	1.567e-83	295.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,2Z0ES@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CMS3_k127_1055313_6	391625.PPSIR1_08002	3.867e-26	119.0	COG0775@1|root,COG0775@2|Bacteria,1RE83@1224|Proteobacteria	1224|Proteobacteria	F	Phosphorylase superfamily	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_1055313_8	1452535.JARD01000012_gene59	0.0001118	54.0	COG4099@1|root,COG4099@2|Bacteria,2GSIX@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd,Peptidase_S9
CMS3_k127_1055313_5	1244869.H261_18752	5.448e-53	198.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,2UBBM@28211|Alphaproteobacteria,2JSZ2@204441|Rhodospirillales	204441|Rhodospirillales	Q	SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS3_k127_107216_3	344747.PM8797T_04585	1.194e-43	176.0	COG4927@1|root,COG4927@2|Bacteria,2IYD9@203682|Planctomycetes	203682|Planctomycetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_107216_0	1033802.SSPSH_001227	8.529e-271	842.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSF_1195.SF3422,iUTI89_1310.UTI89_C3903	PEPCK_ATP
CMS3_k127_107216_4	756272.Plabr_2435	3.025e-16	92.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159,Prenyltrans
CMS3_k127_107216_7	391008.Smal_2281	0.0004244	54.0	COG4232@1|root,COG4232@2|Bacteria,1QWZ3@1224|Proteobacteria,1T30Q@1236|Gammaproteobacteria,1XD9K@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CMS3_k127_107216_1	502025.Hoch_5286	1.55e-192	610.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YWSI@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
CMS3_k127_107216_2	1121440.AUMA01000006_gene1557	1.218e-83	297.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2M93Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_107216_6	224911.27350827	0.0002886	50.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_107216_5	479435.Kfla_4259	5.275e-08	54.0	COG2764@1|root,COG3832@1|root,COG2764@2|Bacteria,COG3832@2|Bacteria,2HUAQ@201174|Actinobacteria,4DU94@85009|Propionibacteriales	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1083826_0	379066.GAU_3915	1.179e-20	99.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1093542_7	1121104.AQXH01000003_gene329	2.943e-06	53.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase
CMS3_k127_1093542_0	497964.CfE428DRAFT_4943	6.353e-240	784.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CMS3_k127_1093542_4	497964.CfE428DRAFT_4944	2.167e-58	218.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_1093542_5	497964.CfE428DRAFT_4946	1.025e-44	175.0	2EK8J@1|root,33DYX@2|Bacteria,46VTQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1093542_1	240016.ABIZ01000001_gene3322	1.191e-98	353.0	COG0438@1|root,COG0438@2|Bacteria,46UG2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1093542_2	497964.CfE428DRAFT_5038	4.37e-98	334.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_1093542_6	1123252.ATZF01000011_gene3132	9.334e-08	66.0	COG0760@1|root,COG0760@2|Bacteria,1V6TT@1239|Firmicutes,4HJFR@91061|Bacilli,27BTR@186824|Thermoactinomycetaceae	91061|Bacilli	O	PPIC-type PPIASE domain	prsA1	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Cu_amine_oxidN1,Rotamase_3,SurA_N_3
CMS3_k127_1093542_3	1522072.IL54_4426	2.399e-69	240.0	COG0220@1|root,COG0220@2|Bacteria,1QTX5@1224|Proteobacteria,2TWA0@28211|Alphaproteobacteria,2KED9@204457|Sphingomonadales	204457|Sphingomonadales	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
CMS3_k127_1101466_27	1249627.D779_1227	2.118e-33	147.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS3_k127_1101466_6	717605.Theco_2322	8.193e-123	414.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,26R8F@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_1101466_12	760568.Desku_1151	4.932e-84	301.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_1101466_11	1248916.ANFY01000007_gene2256	2.819e-84	292.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2K18Y@204457|Sphingomonadales	204457|Sphingomonadales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS3_k127_1101466_22	1232410.KI421421_gene3863	1.278e-45	189.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS3_k127_1101466_39	1385511.N783_18465	0.0001455	52.0	COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,2Y9TY@289201|Pontibacillus	91061|Bacilli	M	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM
CMS3_k127_1101466_21	28258.KP05_04245	3.382e-50	192.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1XIP2@135619|Oceanospirillales	135619|Oceanospirillales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS3_k127_1101466_14	105422.BBPM01000004_gene5358	2.935e-79	282.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,2NFVV@228398|Streptacidiphilus	201174|Actinobacteria	M	Mur ligase family, catalytic domain	murC	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_1101466_19	344747.PM8797T_20978	1.017e-56	212.0	COG0812@1|root,COG0812@2|Bacteria,2IYGQ@203682|Planctomycetes	203682|Planctomycetes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS3_k127_1101466_16	530564.Psta_0052	2.188e-74	266.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Metallophos,Pur_ac_phosph_N
CMS3_k127_1101466_5	469383.Cwoe_3280	9.26e-172	550.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4CPTW@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1101466_18	478741.JAFS01000001_gene1532	1.083e-69	244.0	COG1073@1|root,COG1073@2|Bacteria,46V25@74201|Verrucomicrobia,37G63@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Serine hydrolase (FSH1)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_1101466_3	717774.Marme_2942	6.981e-206	664.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_1101466_32	1129374.AJE_02991	3.257e-10	71.0	2CAAG@1|root,31SID@2|Bacteria,1N50D@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1101466_20	1173022.Cri9333_2782	1.648e-54	204.0	COG0463@1|root,COG0463@2|Bacteria,1GDMZ@1117|Cyanobacteria,1HGCF@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1101466_0	344747.PM8797T_31053	1.95e-319	1027.0	COG2010@1|root,COG2133@1|root,COG2755@1|root,COG3794@1|root,COG3828@1|root,COG4654@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3794@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,2IX6X@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
CMS3_k127_1101466_1	1210884.HG799474_gene15134	4.753e-235	779.0	COG1506@1|root,COG1506@2|Bacteria,2J2ME@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_1101466_29	1122939.ATUD01000010_gene2839	8.425e-29	123.0	COG1403@1|root,COG1403@2|Bacteria,2GV0W@201174|Actinobacteria,4CQF2@84995|Rubrobacteria	84995|Rubrobacteria	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS3_k127_1101466_25	641491.DND132_2038	4.828e-37	159.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42UBK@68525|delta/epsilon subdivisions,2WQU5@28221|Deltaproteobacteria,2M9FJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
CMS3_k127_1101466_2	1122621.ATZA01000004_gene1247	4.131e-227	736.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1IPFU@117747|Sphingobacteriia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS3_k127_1101466_8	1121472.AQWN01000005_gene2490	5.363e-107	372.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
CMS3_k127_1101466_10	1121033.AUCF01000005_gene5309	1.052e-100	346.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,2TTBH@28211|Alphaproteobacteria,2JRMS@204441|Rhodospirillales	204441|Rhodospirillales	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS3_k127_1101466_13	498761.HM1_2508	5.605e-83	286.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS3_k127_1101466_31	1120971.AUCA01000011_gene2928	1.474e-17	93.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,278JM@186823|Alicyclobacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS3_k127_1101466_35	1121428.DESHY_110462___1	2.74e-09	71.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia,263AU@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
CMS3_k127_1101466_4	237368.SCABRO_03706	2.635e-179	594.0	COG0532@1|root,COG0532@2|Bacteria,2IXYU@203682|Planctomycetes	203682|Planctomycetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS3_k127_1101466_9	314230.DSM3645_21614	1.381e-101	346.0	COG0195@1|root,COG0195@2|Bacteria,2IWY3@203682|Planctomycetes	203682|Planctomycetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS3_k127_1101466_38	1101192.KB910516_gene2074	1.364e-06	57.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,1JUER@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS3_k127_1101466_26	671143.DAMO_0254	2.087e-34	142.0	COG2120@1|root,COG2120@2|Bacteria,2NQ6H@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,PIG-L
CMS3_k127_1101466_15	379066.GAU_0663	1.288e-74	267.0	COG1092@1|root,COG1092@2|Bacteria,1ZT8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_1101466_33	1247963.JPHU01000003_gene1341	3.458e-10	72.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2UG5I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_1101466_7	237368.SCABRO_03177	1.228e-109	361.0	COG2022@1|root,COG2022@2|Bacteria,2IY2Y@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
CMS3_k127_1101466_36	1384054.N790_12345	6.361e-09	68.0	COG1266@1|root,COG1266@2|Bacteria,1NID0@1224|Proteobacteria,1SXRS@1236|Gammaproteobacteria,1X6NB@135614|Xanthomonadales	135614|Xanthomonadales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_1101466_23	1396858.Q666_12405	3.939e-45	179.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1S3WC@1236|Gammaproteobacteria,466YX@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS3_k127_1101466_24	269797.Mbar_A2020	7.589e-41	163.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,2N9G1@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transferase
CMS3_k127_1101466_17	1128421.JAGA01000002_gene1226	3.468e-70	246.0	COG1606@1|root,COG1606@2|Bacteria,2NP5T@2323|unclassified Bacteria	2|Bacteria	L	tRNA processing	larE	-	4.99.1.12	ko:K06864,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	ATP_bind_3,Asn_synthase,NAD_synthase,QueC
CMS3_k127_1101466_28	644966.Tmar_0414	7.257e-31	136.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,3WDGI@538999|Clostridiales incertae sedis	186801|Clostridia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1101466_40	460265.Mnod_2754	0.0004016	54.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2U8SM@28211|Alphaproteobacteria,1JTHS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	prtR	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1101466_30	1238182.C882_1350	2.589e-20	102.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,2TSN7@28211|Alphaproteobacteria,2JPCS@204441|Rhodospirillales	204441|Rhodospirillales	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CMS3_k127_1101466_34	1218075.BAYA01000015_gene4273	2e-09	72.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_1128846_0	1121129.KB903372_gene300	1.359e-20	102.0	COG4232@1|root,COG4232@2|Bacteria,4NH5B@976|Bacteroidetes,2FWD6@200643|Bacteroidia,22ZJ9@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CMS3_k127_1128846_1	1254432.SCE1572_14900	6.216e-13	81.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,42RXB@68525|delta/epsilon subdivisions,2WNXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
CMS3_k127_1133548_9	1123508.JH636439_gene1614	2.468e-06	57.0	COG3828@1|root,COG3828@2|Bacteria,2IXPS@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS3_k127_1133548_6	1137271.AZUM01000008_gene2060	4.458e-59	212.0	COG2133@1|root,COG2133@2|Bacteria,2GRVP@201174|Actinobacteria,4DYDK@85010|Pseudonocardiales	201174|Actinobacteria	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,DUF1080,PA14
CMS3_k127_1133548_1	243090.RB10165	1.081e-125	441.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
CMS3_k127_1133548_5	1123242.JH636435_gene3013	4.145e-65	241.0	COG0673@1|root,COG0673@2|Bacteria,2IYHX@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_1133548_7	497964.CfE428DRAFT_0981	5.235e-43	173.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS3_k127_1133548_4	1137269.AZWL01000024_gene1075	2.859e-65	250.0	COG0329@1|root,COG0329@2|Bacteria,2GJEU@201174|Actinobacteria	201174|Actinobacteria	EM	Protein of unknown function (DUF993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF993
CMS3_k127_1133548_3	1209989.TepiRe1_1882	1.412e-101	346.0	COG0673@1|root,COG0673@2|Bacteria,1UIIC@1239|Firmicutes,249KE@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_1133548_0	1122194.AUHU01000007_gene201	1.228e-198	629.0	COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,464VQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glucuronate isomerase	uxaC	GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528	UxaC
CMS3_k127_1133548_2	518766.Rmar_1528	6.622e-122	404.0	2BXG3@1|root,2Z82R@2|Bacteria,4NI3Z@976|Bacteroidetes	976|Bacteroidetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
CMS3_k127_1133548_8	1123242.JH636436_gene649	1.311e-19	99.0	COG3682@1|root,COG3682@2|Bacteria,2J0YJ@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_1141731_5	1191523.MROS_1555	3.583e-65	248.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1141731_1	290318.Cvib_1327	4.006e-99	347.0	COG1132@1|root,COG1132@2|Bacteria,1FDCF@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1141731_4	595460.RRSWK_02101	2.34e-67	262.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,WD40
CMS3_k127_1141731_3	204669.Acid345_4573	1.242e-73	262.0	COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria,2JI6J@204432|Acidobacteriia	204432|Acidobacteriia	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS3_k127_1141731_6	595460.RRSWK_02270	1.207e-47	188.0	COG1663@1|root,COG1663@2|Bacteria,2IXYX@203682|Planctomycetes	203682|Planctomycetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS3_k127_1141731_2	247490.KSU1_C0055	4.615e-76	273.0	COG1899@1|root,COG1899@2|Bacteria,2J4X6@203682|Planctomycetes	203682|Planctomycetes	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1141731_0	269799.Gmet_0922	1.596e-114	400.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
CMS3_k127_1141731_7	373903.Hore_16500	2.942e-33	140.0	COG0615@1|root,COG0615@2|Bacteria,1UJSU@1239|Firmicutes,24MH0@186801|Clostridia,3WAS5@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
CMS3_k127_116533_0	1396141.BATP01000040_gene2103	1.858e-68	244.0	COG3828@1|root,COG3828@2|Bacteria,46VX0@74201|Verrucomicrobia,2IUD7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS3_k127_116533_2	1267533.KB906733_gene2989	4.597e-39	166.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_116533_1	497964.CfE428DRAFT_5952	1.364e-52	209.0	COG0745@1|root,COG0745@2|Bacteria,46V5I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1194607_0	935840.JAEQ01000011_gene1814	4.238e-121	411.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria,43I2S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	rihA	GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008655,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009164,GO:0009165,GO:0009435,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0034356,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0045437,GO:0046135,GO:0046483,GO:0046496,GO:0046497,GO:0046700,GO:0050263,GO:0051186,GO:0051188,GO:0055086,GO:0070635,GO:0070636,GO:0071704,GO:0072521,GO:0072523,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CMS3_k127_1194607_1	105425.BBPL01000046_gene3057	2.572e-76	269.0	COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,2NGK2@228398|Streptacidiphilus	201174|Actinobacteria	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_1194607_2	404589.Anae109_0629	5.543e-23	106.0	COG1232@1|root,COG1232@2|Bacteria,1R5SZ@1224|Proteobacteria,42YX0@68525|delta/epsilon subdivisions,2WTXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS3_k127_1198795_3	452637.Oter_0123	1.302e-62	226.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
CMS3_k127_1198795_4	882082.SaccyDRAFT_0989	4.275e-52	205.0	COG1807@1|root,COG1807@2|Bacteria,2IASE@201174|Actinobacteria,4E1F3@85010|Pseudonocardiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1198795_10	1123504.JQKD01000003_gene672	0.0001224	52.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2VNZN@28216|Betaproteobacteria,4AATF@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_1198795_8	1192034.CAP_8278	1.905e-20	107.0	COG1520@1|root,COG1520@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_1198795_2	1120950.KB892778_gene1042	2.024e-63	248.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1198795_7	485915.Dret_1923	4.053e-25	110.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WP5S@28221|Deltaproteobacteria,2MC10@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_1198795_1	575540.Isop_1807	1.417e-64	252.0	COG0047@1|root,COG0047@2|Bacteria,2IYT2@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CMS3_k127_1198795_0	886293.Sinac_5423	9.034e-274	873.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
CMS3_k127_1198795_9	749414.SBI_00790	2.091e-08	65.0	COG0500@1|root,COG2226@2|Bacteria,2I3TI@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	2.1.1.156	ko:K14374,ko:K18896	ko00260,ko00522,ko01052,ko01130,map00260,map00522,map01052,map01130	M00777	R06476,R06477,R06478,R06479,R10060	RC00003,RC00466,RC03038	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_1198795_6	867845.KI911784_gene2277	5.53e-43	175.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_1198795_5	305700.B447_05685	8.852e-48	184.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2VMDZ@28216|Betaproteobacteria,2KZ2X@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_1205060_8	935863.AWZR01000002_gene1022	9.817e-14	75.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RSG9@1236|Gammaproteobacteria,1X3F8@135614|Xanthomonadales	135614|Xanthomonadales	E	aminopeptidase	pepN	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
CMS3_k127_1205060_2	882083.SacmaDRAFT_2580	1.06e-124	419.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2H0W0@201174|Actinobacteria	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7,NrfD
CMS3_k127_1205060_0	340177.Cag_1964	0.0	1161.0	COG0243@1|root,COG0243@2|Bacteria,1FDP0@1090|Chlorobi	1090|Chlorobi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_1205060_3	240016.ABIZ01000001_gene771	1.571e-115	393.0	28IED@1|root,2Z8GE@2|Bacteria,46VP7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CMS3_k127_1205060_5	497964.CfE428DRAFT_5375	1.752e-57	225.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,46U46@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1205060_1	1211035.CD30_18465	1.685e-201	644.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3IW8K@400634|Lysinibacillus	91061|Bacilli	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS3_k127_1205060_7	1449353.JQMQ01000005_gene3886	4.188e-30	139.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,2NNIR@228398|Streptacidiphilus	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_1205060_4	42256.RradSPS_0735	7.131e-64	227.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1205060_6	583355.Caka_1115	2.072e-41	168.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_1219797_11	88036.EFJ36351	2.753e-17	89.0	2CR9A@1|root,2R7CJ@2759|Eukaryota,37Y51@33090|Viridiplantae,3GPBP@35493|Streptophyta	35493|Streptophyta	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_1219797_12	1157634.KB912943_gene4041	1.357e-06	60.0	COG3595@1|root,COG3595@2|Bacteria,2I8IR@201174|Actinobacteria	201174|Actinobacteria	T	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_1219797_7	497964.CfE428DRAFT_5168	4.399e-44	184.0	2DUSB@1|root,33S06@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1219797_3	497964.CfE428DRAFT_5165	4.532e-111	367.0	COG1131@1|root,COG1131@2|Bacteria,46UCK@74201|Verrucomicrobia	74201|Verrucomicrobia	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_1219797_9	497964.CfE428DRAFT_5164	8.804e-31	142.0	2EY1P@1|root,33RAP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1219797_0	344747.PM8797T_25366	8.466e-140	460.0	COG0673@1|root,COG0673@2|Bacteria,2IYHX@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_1219797_6	388413.ALPR1_02705	5.701e-46	180.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,47MAP@768503|Cytophagia	976|Bacteroidetes	C	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,FGE-sulfatase
CMS3_k127_1219797_4	1121920.AUAU01000011_gene183	2.388e-77	284.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,3Y85P@57723|Acidobacteria	57723|Acidobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,Guanylate_cyc
CMS3_k127_1219797_2	497964.CfE428DRAFT_2365	3.618e-125	410.0	COG1090@1|root,COG1090@2|Bacteria	2|Bacteria	S	coenzyme binding	yfcH	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS3_k127_1219797_8	2002.JOEQ01000013_gene5536	1.723e-31	134.0	COG2764@1|root,COG2764@2|Bacteria,2I27E@201174|Actinobacteria,4EQN9@85012|Streptosporangiales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_1219797_10	1226325.HMPREF1548_00221	6.194e-24	115.0	COG4409@1|root,COG4409@2|Bacteria,1V5Q1@1239|Firmicutes,24FGZ@186801|Clostridia,36W5Z@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
CMS3_k127_1219797_5	1296415.JACC01000025_gene1691	3.305e-71	262.0	2DQMZ@1|root,337PX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1219797_1	1123508.JH636449_gene7418	1.888e-127	427.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1219797_13	1296416.JACB01000017_gene5145	8.044e-06	52.0	COG0236@1|root,COG0236@2|Bacteria,4NM13@976|Bacteroidetes,1HZCB@117743|Flavobacteriia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1229395_0	1254432.SCE1572_22375	1.45e-36	161.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1305558_0	1267535.KB906767_gene3320	1.068e-264	835.0	COG4993@1|root,COG4993@2|Bacteria,3Y639@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
CMS3_k127_1305558_3	595460.RRSWK_05943	7.567e-90	320.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,HisKA_7TM,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS3_k127_1305558_5	595460.RRSWK_06227	2.989e-71	254.0	COG0657@1|root,COG0657@2|Bacteria,2J2MF@203682|Planctomycetes	203682|Planctomycetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_1305558_10	1242864.D187_008552	1.928e-06	61.0	COG2315@1|root,COG2315@2|Bacteria,1Q2G4@1224|Proteobacteria,4382J@68525|delta/epsilon subdivisions,2X3CK@28221|Deltaproteobacteria,2YVFB@29|Myxococcales	28221|Deltaproteobacteria	S	YjbR	difB	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS3_k127_1305558_1	530564.Psta_2234	2.194e-221	713.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CMS3_k127_1305558_2	880070.Cycma_4961	2.491e-175	563.0	COG3119@1|root,COG3119@2|Bacteria,4NGVK@976|Bacteroidetes,47K11@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_1305558_4	1125863.JAFN01000001_gene2573	3.732e-75	266.0	COG1283@1|root,COG1283@2|Bacteria,1MXWU@1224|Proteobacteria	1224|Proteobacteria	P	phosphate symporter	nptA	-	-	ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1	-	-	Na_Pi_cotrans
CMS3_k127_1305558_7	1125863.JAFN01000001_gene2574	1.001e-44	184.0	COG0704@1|root,COG0704@2|Bacteria,1NRGK@1224|Proteobacteria	1224|Proteobacteria	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
CMS3_k127_1305558_6	316067.Geob_3261	1.281e-51	205.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,43AJV@68525|delta/epsilon subdivisions,2X601@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_1305558_9	1313421.JHBV01000026_gene456	4.799e-13	80.0	COG1404@1|root,COG2931@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CMS3_k127_1309941_1	344747.PM8797T_05840	4.2e-63	243.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CMS3_k127_1309941_0	882.DVU_0867	3.477e-77	276.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2M9RN@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
CMS3_k127_1319122_1	243090.RB6961	1.969e-10	69.0	COG1595@1|root,COG1595@2|Bacteria,2J0IJ@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1319122_3	1144275.COCOR_01429	5.15e-05	57.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1319122_2	404589.Anae109_0911	9.104e-08	66.0	COG0793@1|root,COG3485@1|root,COG0793@2|Bacteria,COG3485@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_1319122_0	172088.AUGA01000002_gene6077	7.928e-74	263.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JTJE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
CMS3_k127_139273_3	525897.Dbac_2311	4.235e-18	89.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2M9X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
CMS3_k127_139273_0	382464.ABSI01000011_gene2351	0.0	1614.0	COG0841@1|root,COG0841@2|Bacteria,46Z6Y@74201|Verrucomicrobia,2ITZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_139273_2	1449049.JONW01000001_gene3331	3.02e-18	100.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
CMS3_k127_139273_1	1185876.BN8_04644	8.254e-73	257.0	COG5285@1|root,COG5285@2|Bacteria,4NKN2@976|Bacteroidetes,47MM3@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_1396530_1	756272.Plabr_0106	3.993e-91	312.0	COG2010@1|root,COG2010@2|Bacteria,2IXIX@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,PA14
CMS3_k127_1396530_4	368407.Memar_0976	5.228e-24	112.0	COG2339@1|root,arCOG02985@2157|Archaea	2157|Archaea	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
CMS3_k127_1396530_5	1128421.JAGA01000002_gene620	0.0009522	42.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CMS3_k127_1396530_0	1250232.JQNJ01000001_gene1888	4.015e-210	666.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,1HYII@117743|Flavobacteriia	976|Bacteroidetes	Q	Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_1396530_3	90675.XP_010495842.1	2.423e-27	118.0	KOG0118@1|root,KOG0118@2759|Eukaryota,37V6P@33090|Viridiplantae,3GJFA@35493|Streptophyta	35493|Streptophyta	A	Glycine-rich RNA-binding protein	-	GO:0000166,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006355,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0080090,GO:0090351,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_1396530_2	649349.Lbys_1863	9.664e-66	236.0	COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CMS3_k127_1418839_3	880072.Desac_0610	6.406e-138	452.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_1418839_8	595460.RRSWK_02342	2.347e-92	312.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_1418839_7	595460.RRSWK_04778	2.942e-96	347.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
CMS3_k127_1418839_9	314345.SPV1_05168	1.619e-64	241.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria	1224|Proteobacteria	FJ	deaminase	cdd	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CMS3_k127_1418839_10	592028.GCWU000321_00386	1.052e-61	226.0	COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,4H1ZV@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS3_k127_1418839_0	314230.DSM3645_30206	1.096e-290	918.0	COG0550@1|root,COG0550@2|Bacteria,2IY53@203682|Planctomycetes	203682|Planctomycetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS3_k127_1418839_5	489825.LYNGBM3L_69550	8.912e-124	404.0	COG0379@1|root,COG0379@2|Bacteria,1G17Q@1117|Cyanobacteria,1H7UK@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS3_k127_1418839_1	357808.RoseRS_2562	1.44e-163	528.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS3_k127_1418839_11	713586.KB900536_gene873	7.834e-38	155.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
CMS3_k127_1418839_4	243231.GSU1204	3.281e-134	455.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,43T1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS3_k127_1418839_6	204669.Acid345_1383	9.876e-101	335.0	2CEY7@1|root,2Z8CG@2|Bacteria,3Y70V@57723|Acidobacteria,2JKPR@204432|Acidobacteriia	204432|Acidobacteriia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1418839_2	1210884.HG799466_gene12571	1.738e-141	469.0	COG1053@1|root,COG1053@2|Bacteria,2IX3A@203682|Planctomycetes	203682|Planctomycetes	C	succinate dehydrogenase or fumarate reductase, flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_1489905_4	530564.Psta_1648	1.724e-08	59.0	2DRVG@1|root,33D8Q@2|Bacteria,2J19Z@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1489905_1	575540.Isop_1032	3.685e-104	353.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_1489905_2	888060.HMPREF9081_2084	2.018e-28	125.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4H3BM@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_1489905_6	469383.Cwoe_5680	6.302e-05	56.0	COG2267@1|root,COG2267@2|Bacteria,2GW5Y@201174|Actinobacteria	201174|Actinobacteria	I	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_1489905_5	287.DR97_1556	2.468e-06	57.0	COG0500@1|root,COG0500@2|Bacteria,1R4H7@1224|Proteobacteria,1S55S@1236|Gammaproteobacteria,1YDC5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_1489905_0	1254432.SCE1572_27670	1.033e-160	530.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2YUER@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS3_k127_1489905_3	530564.Psta_2330	1.725e-15	85.0	COG1595@1|root,COG1595@2|Bacteria,2IZ91@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_15055_13	391625.PPSIR1_38616	3.104e-27	114.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJBM@28221|Deltaproteobacteria,2YTUN@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS3_k127_15055_15	1121406.JAEX01000023_gene1484	3.067e-10	70.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MDHW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS3_k127_15055_18	391625.PPSIR1_29553	0.0007884	53.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	391625.PPSIR1_29553|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_15055_2	504472.Slin_6381	2.259e-110	374.0	COG2942@1|root,COG2942@2|Bacteria,4NHTQ@976|Bacteroidetes,47KVQ@768503|Cytophagia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CMS3_k127_15055_7	1434325.AZQN01000006_gene3304	8.438e-52	201.0	COG0546@1|root,COG2870@1|root,COG0546@2|Bacteria,COG2870@2|Bacteria,4NJ8F@976|Bacteroidetes,47MRA@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,PfkB
CMS3_k127_15055_0	314230.DSM3645_07745	6.716e-228	718.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS3_k127_15055_4	330214.NIDE3701	2.065e-107	359.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
CMS3_k127_15055_10	1487953.JMKF01000004_gene647	2.238e-42	157.0	COG0599@1|root,COG0599@2|Bacteria,1G8UR@1117|Cyanobacteria	1117|Cyanobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_15055_14	1415780.JPOG01000001_gene3405	6.426e-16	89.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,1SBRG@1236|Gammaproteobacteria,1X6ZH@135614|Xanthomonadales	135614|Xanthomonadales	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
CMS3_k127_15055_3	292459.STH2811	3.587e-108	357.0	COG3324@1|root,COG3324@2|Bacteria,1VD9A@1239|Firmicutes	1239|Firmicutes	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_15055_12	670487.Ocepr_1763	3.92e-28	129.0	COG0128@1|root,COG0128@2|Bacteria,1WI9P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS3_k127_15055_6	243231.GSU2091	2.725e-102	344.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS3_k127_15055_9	1121403.AUCV01000002_gene609	7.231e-45	168.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2MIPF@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
CMS3_k127_15055_5	344747.PM8797T_04555	8.539e-104	356.0	COG0182@1|root,COG0182@2|Bacteria,2IWRJ@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS3_k127_15055_16	266940.Krad_0406	5.409e-06	60.0	COG1595@1|root,COG1595@2|Bacteria,2IMV5@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_15055_8	742823.HMPREF9465_00474	3.648e-47	196.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,4PQEC@995019|Sutterellaceae	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS3_k127_15055_1	926551.KB900717_gene238	7.354e-117	388.0	COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1HYHY@117743|Flavobacteriia,1ESQV@1016|Capnocytophaga	976|Bacteroidetes	C	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_15055_11	243090.RB10785	5.259e-37	153.0	COG0582@1|root,COG0582@2|Bacteria,2IYXX@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS3_k127_154555_3	1095769.CAHF01000023_gene439	8.828e-28	132.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_154555_6	1095769.CAHF01000023_gene438	4.587e-11	73.0	2C3QT@1|root,32YUW@2|Bacteria,1P8VZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_154555_1	497964.CfE428DRAFT_3663	2.616e-38	168.0	COG1657@1|root,COG1657@2|Bacteria,46V9U@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_154555_7	1120705.FG95_01747	2.005e-08	69.0	COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,2UKB8@28211|Alphaproteobacteria,2K99E@204457|Sphingomonadales	204457|Sphingomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_154555_4	1201290.M902_1137	2.337e-16	84.0	COG0848@1|root,COG0848@2|Bacteria,1NJ5R@1224|Proteobacteria,42XAY@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS3_k127_154555_2	754477.Q7C_1288	7.568e-29	129.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,460KS@72273|Thiotrichales	72273|Thiotrichales	U	MotA TolQ ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_154555_5	1499967.BAYZ01000068_gene1943	4.631e-15	90.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,2NRIW@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16,TPR_6,TPR_8
CMS3_k127_154555_0	595460.RRSWK_04667	9.427e-156	516.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2IY1G@203682|Planctomycetes	203682|Planctomycetes	P	COG0038 Chloride channel protein EriC	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS3_k127_1585796_3	105559.Nwat_0946	1.351e-18	101.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WX0W@135613|Chromatiales	135613|Chromatiales	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_1585796_2	1249627.D779_3748	1.654e-38	153.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WX0W@135613|Chromatiales	135613|Chromatiales	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS3_k127_1585796_1	518766.Rmar_1770	6.066e-85	294.0	COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,1FJR1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ABC transporter	gldA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1585796_0	504832.OCAR_4382	5.296e-103	356.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,3JQY5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS3_k127_158671_14	861299.J421_3225	2.589e-44	175.0	COG2121@1|root,COG2121@2|Bacteria,1ZTU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
CMS3_k127_158671_29	591157.SSLG_05833	9.829e-09	69.0	COG0400@1|root,COG0400@2|Bacteria,2IJV2@201174|Actinobacteria	201174|Actinobacteria	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
CMS3_k127_158671_20	665959.HMPREF1013_05296	7.675e-35	151.0	COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus	91061|Bacilli	M	n-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,LysM
CMS3_k127_158671_13	765420.OSCT_0910	5.64e-47	188.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
CMS3_k127_158671_25	1123252.ATZF01000027_gene1612	1.29e-16	93.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS3_k127_158671_10	886293.Sinac_2761	8.561e-65	253.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_158671_16	886293.Sinac_7484	9.771e-41	159.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_158671_3	1129794.C427_1223	4.566e-121	420.0	COG2706@1|root,COG3391@1|root,COG3637@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,COG3637@2|Bacteria,1QWRQ@1224|Proteobacteria,1T4S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_158671_33	326427.Cagg_2317	0.0007648	49.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_158671_11	886293.Sinac_7479	6.582e-59	235.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_158671_30	1144275.COCOR_07912	2.95e-06	60.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_158671_9	886293.Sinac_6489	2.589e-70	273.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_158671_28	530564.Psta_2501	2.64e-09	66.0	COG1595@1|root,COG1595@2|Bacteria,2J02A@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_158671_12	391596.PBAL39_23752	2.627e-54	209.0	2EBZK@1|root,335YW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_158671_7	290397.Adeh_1281	6.369e-83	284.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2YWX3@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS3_k127_158671_5	665571.STHERM_c12900	1.315e-108	400.0	COG0031@1|root,COG0031@2|Bacteria,2J5EE@203691|Spirochaetes	203691|Spirochaetes	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_158671_6	886293.Sinac_3618	4.687e-102	376.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_158671_32	557599.MKAN_03425	0.0003906	52.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria,235MW@1762|Mycobacteriaceae	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_158671_17	756272.Plabr_0708	3.339e-40	155.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_158671_18	411684.HPDFL43_12398	9.212e-40	156.0	COG1309@1|root,COG1309@2|Bacteria,1PFV3@1224|Proteobacteria,2V7XI@28211|Alphaproteobacteria,43QPX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_158671_19	1242864.D187_003712	3.736e-37	160.0	COG1670@1|root,COG1670@2|Bacteria,1P18R@1224|Proteobacteria	2|Bacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_158671_1	243090.RB12118	4.685e-209	701.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_158671_0	243090.RB714	3.243e-272	863.0	COG1566@1|root,COG4096@1|root,COG1566@2|Bacteria,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	tccB2	-	-	ko:K02004,ko:K06218,ko:K16552	-	M00258	-	-	ko00000,ko00002,ko02000,ko02048	1.B.18.1,3.A.1	-	-	DivIVA,Poly_export,ResIII,SLBB
CMS3_k127_158671_23	330214.NIDE0685	9.458e-18	93.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679,ko:K08084	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin_GH
CMS3_k127_158671_21	234267.Acid_4124	7.882e-33	149.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
CMS3_k127_158671_8	234267.Acid_1856	6.025e-71	263.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y45M@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,SpoIIE
CMS3_k127_158671_24	1121272.KB903253_gene6839	1.02e-17	94.0	2C73B@1|root,3190M@2|Bacteria,2HX02@201174|Actinobacteria,4DKV2@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_158671_22	502025.Hoch_4961	6.951e-22	113.0	COG1520@1|root,COG1520@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_158671_2	1122939.ATUD01000001_gene577	1.194e-124	435.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_158671_27	469371.Tbis_3432	1.13e-12	76.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_158671_4	1267535.KB906767_gene447	1.672e-113	400.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_158671_15	1254432.SCE1572_39920	1.658e-42	173.0	COG3464@1|root,COG3464@2|Bacteria,1NPPU@1224|Proteobacteria,43BG7@68525|delta/epsilon subdivisions,2X6UI@28221|Deltaproteobacteria,2Z33P@29|Myxococcales	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1600943_1	761193.Runsl_5037	8.905e-235	785.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,47MKW@768503|Cytophagia	976|Bacteroidetes	E	Dipeptidyl peptidase IV	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_1600943_7	314230.DSM3645_10902	1.065e-142	481.0	COG0823@1|root,COG1506@1|root,COG4805@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,COG4805@2|Bacteria,2IY8M@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,DUF885,Peptidase_S9,VHL
CMS3_k127_1600943_27	1242864.D187_010069	4.06e-59	232.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
CMS3_k127_1600943_53	1121430.JMLG01000019_gene1643	4.496e-05	55.0	COG5662@1|root,COG5662@2|Bacteria,1VKS6@1239|Firmicutes,24VD1@186801|Clostridia	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_1600943_42	1206735.BAGG01000101_gene4353	1.244e-20	100.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,4FXX7@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1600943_51	472759.Nhal_3187	2.152e-05	58.0	COG3577@1|root,COG3577@2|Bacteria,1RAQK@1224|Proteobacteria,1S2GF@1236|Gammaproteobacteria,1WY1Z@135613|Chromatiales	135613|Chromatiales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
CMS3_k127_1600943_50	105422.BBPM01000023_gene3488	6.778e-07	61.0	COG3595@1|root,COG3595@2|Bacteria,2HUCQ@201174|Actinobacteria,2NJEA@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS3_k127_1600943_47	314230.DSM3645_26924	3.482e-09	64.0	COG2204@1|root,COG2204@2|Bacteria,2IY45@203682|Planctomycetes	203682|Planctomycetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_1600943_37	420324.KI911943_gene5343	1.473e-37	153.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_1600943_15	449447.MAE_61060	2.034e-93	329.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
CMS3_k127_1600943_12	648996.Theam_0242	1.196e-119	393.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_1600943_4	316274.Haur_2746	3.293e-153	500.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,3751F@32061|Chloroflexia	32061|Chloroflexia	F	TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS3_k127_1600943_32	123899.JPQP01000020_gene2013	3.384e-45	179.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,3T1NG@506|Alcaligenaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS3_k127_1600943_24	864051.BurJ1DRAFT_2646	2.611e-66	258.0	2FGUZ@1|root,348QA@2|Bacteria,1NZWU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1600943_55	1242864.D187_001420	0.0007031	52.0	2FAP7@1|root,342WV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1600943_43	1121405.dsmv_0885	3.243e-20	107.0	2EYSQ@1|root,33RZZ@2|Bacteria,1NRGW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1600943_41	512565.AMIS_4880	1.666e-27	126.0	COG0535@1|root,COG0535@2|Bacteria,2GTTW@201174|Actinobacteria,4DIAW@85008|Micromonosporales	201174|Actinobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_1600943_5	1403819.BATR01000018_gene577	3.586e-149	481.0	COG4409@1|root,COG4409@2|Bacteria,46SCF@74201|Verrucomicrobia,2IVXN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_1600943_30	1278073.MYSTI_02462	3.351e-47	185.0	COG0793@1|root,COG3577@1|root,COG0793@2|Bacteria,COG3577@2|Bacteria,1NICY@1224|Proteobacteria	1224|Proteobacteria	M	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
CMS3_k127_1600943_17	1487923.DP73_09690	2.341e-80	278.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
CMS3_k127_1600943_25	1191523.MROS_2810	8.21e-63	227.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_1600943_20	344747.PM8797T_14691	6.828e-70	251.0	COG1191@1|root,COG1191@2|Bacteria,2IX9S@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_1600943_26	886293.Sinac_6448	1.401e-59	210.0	COG0503@1|root,COG0503@2|Bacteria,2IZ9H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS3_k127_1600943_19	886293.Sinac_6694	1.826e-71	276.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_1600943_48	644282.Deba_2532	1.855e-08	67.0	COG0500@1|root,COG2226@2|Bacteria,1NERR@1224|Proteobacteria,42XR5@68525|delta/epsilon subdivisions,2WSYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_1600943_14	1123288.SOV_1c10980	2.289e-105	352.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4H2A2@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_1600943_18	391625.PPSIR1_02136	3.552e-78	274.0	COG0664@1|root,COG0664@2|Bacteria,1R5Z0@1224|Proteobacteria,42Q0Q@68525|delta/epsilon subdivisions,2WKKJ@28221|Deltaproteobacteria,2YVXW@29|Myxococcales	28221|Deltaproteobacteria	T	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20,cNMP_binding
CMS3_k127_1600943_52	1500259.JQLD01000002_gene2823	2.173e-05	54.0	COG1595@1|root,COG1595@2|Bacteria,1RKMN@1224|Proteobacteria,2U9GS@28211|Alphaproteobacteria,4BDTH@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1600943_34	404589.Anae109_2865	1.586e-43	177.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,42XV1@68525|delta/epsilon subdivisions,2WSUD@28221|Deltaproteobacteria,2YV76@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_1600943_36	382464.ABSI01000010_gene3665	3.452e-40	161.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxO	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS3_k127_1600943_22	382464.ABSI01000010_gene3667	9.089e-67	236.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,2IU4E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c oxidase subunit III	-	-	-	-	-	-	-	-	-	-	-	-	COX3
CMS3_k127_1600943_0	382464.ABSI01000010_gene3668	2.218e-273	856.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,2ITKY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CMS3_k127_1600943_21	382464.ABSI01000010_gene3669	2.654e-68	238.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia,2IU8P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	COX2
CMS3_k127_1600943_35	382464.ABSI01000010_gene3670	2.255e-43	173.0	COG2863@1|root,COG2863@2|Bacteria,46WZQ@74201|Verrucomicrobia,2IW1M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_1600943_28	1128421.JAGA01000003_gene3091	1.35e-49	201.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_1600943_3	869210.Marky_1642	2.696e-175	563.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_1600943_38	1123393.KB891316_gene1485	8.243e-35	139.0	COG2846@1|root,COG2846@2|Bacteria,1QX13@1224|Proteobacteria,2WH3K@28216|Betaproteobacteria,1KRV2@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_1600943_49	713586.KB900536_gene2237	4.2e-08	63.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	ko:K08363	-	-	-	-	ko00000,ko02000	1.A.72.1	-	-	DUF2249,TusA
CMS3_k127_1600943_29	1198452.Jab_2c11040	1.691e-49	196.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,2VNAW@28216|Betaproteobacteria,4747X@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1600943_10	1232410.KI421412_gene166	1.051e-120	400.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1600943_6	648757.Rvan_0035	5.623e-149	479.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_1600943_23	443144.GM21_2822	1.032e-66	236.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_1600943_9	258594.RPA0657	3.595e-129	436.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2U2IH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_1600943_2	652103.Rpdx1_4128	5.859e-198	625.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
CMS3_k127_1600943_8	1187851.A33M_3198	1.327e-137	467.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
CMS3_k127_1600943_16	85643.Tmz1t_2948	1.27e-85	310.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,2VSQQ@28216|Betaproteobacteria,2KXX8@206389|Rhodocyclales	206389|Rhodocyclales	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
CMS3_k127_1600943_33	479435.Kfla_3714	9.023e-44	176.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4DPI8@85009|Propionibacteriales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_1600943_39	1187851.A33M_3201	1.611e-32	141.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_1600943_31	870187.Thini_3864	4.326e-47	173.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S8W1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_1600943_56	1215092.PA6_024_00730	0.0008285	47.0	2DXXZ@1|root,3475N@2|Bacteria,1P2WY@1224|Proteobacteria,1ST3H@1236|Gammaproteobacteria,1YGQS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
CMS3_k127_1600943_11	1254432.SCE1572_47525	3.594e-120	402.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YTZB@29|Myxococcales	28221|Deltaproteobacteria	E	synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_1600943_13	1396418.BATQ01000109_gene4733	1.52e-107	370.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_1600943_44	653733.Selin_2060	5.092e-12	72.0	2DN81@1|root,32W0Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1600943_40	1239962.C943_00187	3.466e-32	136.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_1609805_2	104623.Ser39006_03461	8.375e-16	83.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,403BE@613|Serratia	1236|Gammaproteobacteria	U	General secretion pathway protein	gspG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_1609805_5	1177154.Y5S_01081	0.0005439	51.0	COG4969@1|root,COG4969@2|Bacteria,1R1Z5@1224|Proteobacteria,1T5DS@1236|Gammaproteobacteria,1XMKN@135619|Oceanospirillales	135619|Oceanospirillales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS3_k127_1609805_4	404589.Anae109_0724	5.21e-06	59.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria,2YVMW@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CMS3_k127_1609805_0	867903.ThesuDRAFT_01146	1.702e-128	426.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WCCW@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS3_k127_1609805_3	867900.Celly_0255	3.756e-13	79.0	COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia,1F8PB@104264|Cellulophaga	976|Bacteroidetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_1609805_1	83219.PM02_15410	5.974e-85	290.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,3ZWD1@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS3_k127_1640280_2	1121423.JONT01000015_gene1363	5.439e-204	676.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,2601Q@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS3_k127_1640280_35	1089549.AZUQ01000001_gene2352	0.0001157	50.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,4EY8A@85014|Glycomycetales	201174|Actinobacteria	C	BFD-like [2Fe-2S] binding domain	nasC	-	-	ko:K00360	ko00910,ko01120,map00910,map01120	M00531	R00798	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Pyr_redox_2
CMS3_k127_1640280_33	215803.DB30_2422	1.697e-09	71.0	COG0750@1|root,COG4932@1|root,COG0750@2|Bacteria,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1640280_31	1242864.D187_003866	8.061e-16	92.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_1640280_32	448385.sce9258	1.994e-10	74.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1640280_6	937777.Deipe_2732	2.419e-138	449.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11,4.1.1.45	ko:K00453,ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R00678,R04323	RC00356,RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CMS3_k127_1640280_12	1131269.AQVV01000003_gene693	5.942e-92	312.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
CMS3_k127_1640280_3	530564.Psta_2754	4.085e-168	548.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	2|Bacteria	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	SASA
CMS3_k127_1640280_29	378806.STAUR_3209	9.461e-24	117.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1640280_30	1121106.JQKB01000176_gene5595	1.636e-20	101.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,2JSGU@204441|Rhodospirillales	204441|Rhodospirillales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_1640280_22	671143.DAMO_0253	1.901e-39	167.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
CMS3_k127_1640280_14	1122921.KB898192_gene2204	4.08e-69	245.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26TPG@186822|Paenibacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_1640280_8	373994.Riv7116_2716	2.318e-117	392.0	COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1HKTB@1161|Nostocales	1117|Cyanobacteria	U	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CMS3_k127_1640280_25	1121423.JONT01000002_gene2365	2.056e-30	132.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,260JN@186807|Peptococcaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS3_k127_1640280_21	929712.KI912613_gene182	2.798e-40	166.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS3_k127_1640280_4	926554.KI912625_gene702	4.328e-163	524.0	COG0821@1|root,COG0821@2|Bacteria,1WJ94@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS3_k127_1640280_1	1123253.AUBD01000009_gene2225	5.894e-211	669.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1X3CQ@135614|Xanthomonadales	135614|Xanthomonadales	E	Transporter	yhiP	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS3_k127_1640280_34	479432.Sros_3204	6.045e-05	46.0	COG4912@1|root,COG4912@2|Bacteria,2GNC9@201174|Actinobacteria,4EH34@85012|Streptosporangiales	201174|Actinobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS3_k127_1640280_15	526227.Mesil_2684	2.378e-68	237.0	COG1028@1|root,COG1028@2|Bacteria,1WKXM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1640280_20	63737.Npun_DR029	5.304e-44	176.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF5011,FG-GAP_2,NHL
CMS3_k127_1640280_7	1254432.SCE1572_14685	4.727e-133	437.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS3_k127_1640280_13	477641.MODMU_4803	8.507e-77	266.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4EUCR@85013|Frankiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_1640280_0	1254432.SCE1572_30430	1.517e-217	701.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X250@28221|Deltaproteobacteria,2YXZE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_1640280_9	1205910.B005_0206	2.128e-113	374.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4EIC0@85012|Streptosporangiales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS3_k127_1640280_23	1125863.JAFN01000001_gene1842	3.305e-34	139.0	294JI@1|root,2ZRZ3@2|Bacteria,1REGD@1224|Proteobacteria,4318B@68525|delta/epsilon subdivisions,2WWR0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4863
CMS3_k127_1640280_19	768671.ThimaDRAFT_2627	1.524e-61	234.0	COG0500@1|root,COG0500@2|Bacteria,1R1KF@1224|Proteobacteria,1T54U@1236|Gammaproteobacteria,1X0U9@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1640280_24	313612.L8106_09571	1.969e-33	146.0	COG3011@1|root,COG3011@2|Bacteria,1GBBP@1117|Cyanobacteria,1HDV0@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,VKG_Carbox
CMS3_k127_1640280_10	867903.ThesuDRAFT_01029	8.317e-105	356.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WCUZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_1640280_11	867903.ThesuDRAFT_01030	4.456e-95	328.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WCUZ@538999|Clostridiales incertae sedis	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_1640280_18	1210884.HG799467_gene13172	2.429e-63	222.0	COG0521@1|root,COG0521@2|Bacteria,2IYUD@203682|Planctomycetes	203682|Planctomycetes	H	Molybdenum cofactor biosynthesis	-	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS3_k127_1640280_26	1210884.HG799463_gene9334	3.652e-28	123.0	COG0220@1|root,COG0220@2|Bacteria,2IZJM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS3_k127_1640280_5	1449126.JQKL01000057_gene2241	1.551e-141	473.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,267P2@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
CMS3_k127_1640280_27	247490.KSU1_C1191	1.978e-26	124.0	COG4591@1|root,COG4591@2|Bacteria,2IY15@203682|Planctomycetes	203682|Planctomycetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS3_k127_1640280_16	575540.Isop_2675	3.564e-68	241.0	COG1136@1|root,COG1136@2|Bacteria,2IYZ3@203682|Planctomycetes	203682|Planctomycetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
CMS3_k127_1640280_28	886293.Sinac_5022	5.001e-26	122.0	COG4591@1|root,COG4591@2|Bacteria,2IY15@203682|Planctomycetes	203682|Planctomycetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS3_k127_1640280_17	1237149.C900_01775	2.447e-65	244.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_1668952_5	1123405.AUMM01000007_gene921	2.519e-28	121.0	COG0531@1|root,COG0531@2|Bacteria,1V0MG@1239|Firmicutes,4HDX4@91061|Bacilli	91061|Bacilli	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_1668952_4	1385517.N800_12720	6.141e-41	156.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S69Q@1236|Gammaproteobacteria,1X8MY@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_1668952_1	1379698.RBG1_1C00001G0698	2.205e-248	791.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
CMS3_k127_1668952_6	1125863.JAFN01000001_gene2568	0.000442	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS3_k127_1668952_3	595460.RRSWK_02460	1.856e-181	582.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_1668952_0	530564.Psta_4557	2.514e-306	980.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_1668952_2	314230.DSM3645_06756	9.024e-238	743.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_16743_2	344747.PM8797T_14911	7.305e-33	128.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_16743_1	530564.Psta_0024	7.688e-104	343.0	COG1028@1|root,COG1028@2|Bacteria,2J3E2@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_16743_0	760192.Halhy_0663	0.0	1142.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_1698052_27	1117108.PAALTS15_28286	4.907e-08	63.0	COG1266@1|root,COG1266@2|Bacteria,1UUMR@1239|Firmicutes,4HDXH@91061|Bacilli,26UDJ@186822|Paenibacillaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_1698052_26	497964.CfE428DRAFT_3347	3.625e-10	66.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
CMS3_k127_1698052_13	1499967.BAYZ01000014_gene6406	2.249e-42	165.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS3_k127_1698052_18	1210884.HG799463_gene9897	6.095e-30	134.0	COG0500@1|root,COG2226@2|Bacteria,2J51A@203682|Planctomycetes	203682|Planctomycetes	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_1698052_4	247490.KSU1_D0930	4.197e-95	330.0	COG1232@1|root,COG1232@2|Bacteria,2IYF5@203682|Planctomycetes	2|Bacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8,Radical_SAM,SPASM
CMS3_k127_1698052_14	439235.Dalk_1807	5.05e-42	168.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.7.1.52,2.7.7.13,5.4.2.8	ko:K00966,ko:K05305,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818,R03161	RC00002,RC00078,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
CMS3_k127_1698052_28	296591.Bpro_2523	2.929e-07	64.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1PVBG@1224|Proteobacteria,2WB76@28216|Betaproteobacteria,4AH21@80864|Comamonadaceae	28216|Betaproteobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_1698052_5	247490.KSU1_C0960	1.576e-94	318.0	COG0552@1|root,COG0552@2|Bacteria,2IXAG@203682|Planctomycetes	203682|Planctomycetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS3_k127_1698052_16	247490.KSU1_C0961	4.291e-34	138.0	COG0613@1|root,COG0781@1|root,COG0613@2|Bacteria,COG0781@2|Bacteria,2J058@203682|Planctomycetes	203682|Planctomycetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB,PHP
CMS3_k127_1698052_15	445973.CLOBAR_00906	2.249e-37	146.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,25RA5@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS3_k127_1698052_17	747365.Thena_0983	1.286e-33	138.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS3_k127_1698052_23	926566.Terro_3821	1.307e-24	112.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria,2JI6U@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_1698052_9	515635.Dtur_0404	2.084e-56	211.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
CMS3_k127_1698052_11	595460.RRSWK_00209	3.927e-52	205.0	COG1657@1|root,COG1657@2|Bacteria,2IXAS@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
CMS3_k127_1698052_21	330214.NIDE3579	4.41e-26	126.0	COG3222@1|root,COG3222@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS3_k127_1698052_20	377629.TERTU_2984	4.541e-28	124.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria,2PQGR@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CMS3_k127_1698052_19	880073.Calab_0082	3.497e-29	136.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1698052_1	648996.Theam_0589	1.094e-125	413.0	COG0436@1|root,COG0436@2|Bacteria,2G3PX@200783|Aquificae	200783|Aquificae	E	PFAM Aminotransferase class I and II	dapC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_1698052_2	1242864.D187_000985	1.478e-107	354.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,42SPQ@68525|delta/epsilon subdivisions,2WPX1@28221|Deltaproteobacteria,2YWQX@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CMS3_k127_1698052_7	1158345.JNLL01000001_gene1718	4.177e-88	314.0	COG0624@1|root,COG0624@2|Bacteria,2G4GT@200783|Aquificae	200783|Aquificae	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_1698052_25	383372.Rcas_3458	1.468e-11	68.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS3_k127_1698052_24	1123392.AQWL01000006_gene573	8.798e-18	87.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,2VU52@28216|Betaproteobacteria,1KT5Y@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_1698052_0	477974.Daud_0168	4.407e-202	666.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CMS3_k127_1698052_8	1125863.JAFN01000001_gene3414	2.004e-58	230.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS3_k127_1698052_12	1134445.AJJM01000110_gene3947	4.437e-44	179.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_1698052_10	383372.Rcas_2155	3.937e-54	202.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi,376BZ@32061|Chloroflexia	32061|Chloroflexia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_1698052_6	1121472.AQWN01000009_gene340	2.93e-88	309.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,260K8@186807|Peptococcaceae	186801|Clostridia	P	PFAM TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS3_k127_1698052_3	2903.EOD12957	3.318e-96	340.0	COG0457@1|root,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_4,TPR_7,TPR_8
CMS3_k127_1777005_0	1396141.BATP01000023_gene711	3.933e-97	331.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_1777005_2	706587.Desti_1725	1.165e-55	200.0	COG0225@1|root,COG0225@2|Bacteria,1N2DQ@1224|Proteobacteria,42UC3@68525|delta/epsilon subdivisions,2WQBZ@28221|Deltaproteobacteria,2MS4Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Peptide methionine sulfoxide reductase	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS3_k127_1777005_1	530564.Psta_3944	8.16e-65	235.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS3_k127_1777005_4	886293.Sinac_1102	3.708e-31	125.0	COG0526@1|root,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1777005_5	1210884.HG799463_gene10186	4.776e-21	106.0	COG0526@1|root,COG0526@2|Bacteria,2J07Q@203682|Planctomycetes	203682|Planctomycetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1777005_3	1210884.HG799471_gene14563	4.194e-40	162.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1782994_2	321327.CYA_0133	9.924e-132	441.0	COG1022@1|root,COG1022@2|Bacteria,1G1QY@1117|Cyanobacteria,1GZ6Z@1129|Synechococcus	1117|Cyanobacteria	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS3_k127_1782994_13	1112204.GPOL_174p01620	1.545e-11	71.0	2EDJG@1|root,337FB@2|Bacteria,2GTK4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1782994_12	105425.BBPL01000013_gene1690	5.707e-21	97.0	COG0640@1|root,COG0640@2|Bacteria,2H1MC@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_1782994_3	530564.Psta_1051	6.423e-103	343.0	COG1611@1|root,COG1989@1|root,COG1611@2|Bacteria,COG1989@2|Bacteria,2IZCH@203682|Planctomycetes	203682|Planctomycetes	NOU	Possible lysine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
CMS3_k127_1782994_6	653733.Selin_2251	2.128e-66	250.0	COG1489@1|root,COG1489@2|Bacteria	2|Bacteria	S	positive regulation of transcription, DNA-templated	sfsA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
CMS3_k127_1782994_7	1411123.JQNH01000001_gene688	1.726e-61	235.0	COG1082@1|root,COG1082@2|Bacteria,1NHXC@1224|Proteobacteria,2U3WP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1782994_8	862517.HMPREF9225_0204	8.211e-49	192.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,22GG8@1570339|Peptoniphilaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1782994_9	1519464.HY22_11275	2.216e-46	190.0	COG0577@1|root,COG0577@2|Bacteria,1FEN8@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_1782994_15	1254432.SCE1572_08190	1.165e-08	68.0	COG3495@1|root,COG3495@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
CMS3_k127_1782994_11	1121468.AUBR01000075_gene1102	1.577e-25	122.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,42G86@68295|Thermoanaerobacterales	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4
CMS3_k127_1782994_1	555779.Dthio_PD2758	3.014e-135	455.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,2M9T7@213115|Desulfovibrionales	28221|Deltaproteobacteria	EQ	PFAM Hydantoinase oxoprolinase	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS3_k127_1782994_10	498761.HM1_1986	7.129e-27	118.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS3_k127_1782994_5	886293.Sinac_2703	9.498e-83	301.0	COG0240@1|root,COG0240@2|Bacteria,2IWWN@203682|Planctomycetes	203682|Planctomycetes	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS3_k127_1782994_14	926560.KE387023_gene2060	9.717e-11	64.0	COG4877@1|root,COG4877@2|Bacteria,1WKMS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
CMS3_k127_1782994_4	1121377.KB906400_gene1454	5.892e-91	308.0	COG0330@1|root,COG0330@2|Bacteria,1WIW0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_1782994_0	344747.PM8797T_24306	1.018e-145	494.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
CMS3_k127_1782994_16	252305.OB2597_16030	1.623e-05	58.0	COG1572@1|root,COG1864@1|root,COG3209@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG1864@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1QW4H@1224|Proteobacteria	1224|Proteobacteria	M	Rhs Family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Big_3_2,Big_3_5,DUF4082,DUF4347,He_PIG
CMS3_k127_1784555_4	1265490.JHVY01000021_gene3693	1.268e-07	64.0	COG1621@1|root,COG1621@2|Bacteria,1N5AZ@1224|Proteobacteria,1T04N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1784555_2	384765.SIAM614_23112	4.86e-72	258.0	COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,2VER2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NADPH-quinone reductase (modulator of drug activity B)	-	-	1.6.5.2	ko:K00355,ko:K11748	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000,ko02000	2.A.37.1.2	-	-	Flavodoxin_2
CMS3_k127_1784555_0	384765.SIAM614_23107	2.701e-243	770.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_1784555_1	1239415.CM001837_gene1380	5.312e-139	474.0	COG4188@1|root,COG4188@2|Bacteria,4NKC2@976|Bacteroidetes,1HZ4A@117743|Flavobacteriia,37ED6@326319|Dokdonia	976|Bacteroidetes	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
CMS3_k127_1784555_3	517418.Ctha_2414	1.898e-15	84.0	COG3495@1|root,COG3495@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
CMS3_k127_1784555_5	1304883.KI912532_gene1357	9.613e-05	54.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KVHE@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_1787881_9	391625.PPSIR1_13970	4.907e-19	90.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2,Exo_endo_phos,PAP_central
CMS3_k127_1787881_12	886293.Sinac_3944	1.369e-07	60.0	COG1595@1|root,COG1595@2|Bacteria,2IZS9@203682|Planctomycetes	203682|Planctomycetes	K	RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r4_2
CMS3_k127_1787881_3	1210884.HG799472_gene14748	2.173e-53	214.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1787881_10	1144275.COCOR_01518	6.749e-17	97.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_1787881_6	713586.KB900536_gene2272	1.49e-36	158.0	COG2928@1|root,COG2928@2|Bacteria,1R79M@1224|Proteobacteria,1S6CC@1236|Gammaproteobacteria,1WZFF@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS3_k127_1787881_4	756272.Plabr_1308	9.153e-51	205.0	COG0438@1|root,COG0438@2|Bacteria,2J06C@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	2.4.1.52	ko:K00712	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_1787881_7	243231.GSU3460	3.68e-35	145.0	COG1215@1|root,COG2344@1|root,COG1215@2|Bacteria,COG2344@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,43S6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_1787881_1	269482.Bcep1808_0810	5.198e-122	402.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2VJ5C@28216|Betaproteobacteria,1K2RP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	3.2.1.183,5.1.3.14	ko:K01791,ko:K08068	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CMS3_k127_1787881_0	1303518.CCALI_00772	3.345e-138	446.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_1787881_2	243233.MCA3070	1.941e-77	267.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS3_k127_1787881_5	379066.GAU_3114	1.544e-37	160.0	COG3016@1|root,COG3016@2|Bacteria,1ZUD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
CMS3_k127_1787881_13	76114.ebA2969	3.72e-05	56.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,2KVHE@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
CMS3_k127_1787881_8	1267533.KB906739_gene2485	1.385e-20	99.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_1787881_11	379066.GAU_0985	2.207e-15	87.0	COG1413@1|root,COG4219@1|root,COG1413@2|Bacteria,COG4219@2|Bacteria,1ZUUA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Peptidase_M56
CMS3_k127_1802611_0	502025.Hoch_3204	0.0	1276.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,2YTST@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_1809414_11	100226.SCO0420	1.71e-08	63.0	COG0460@1|root,COG0460@2|Bacteria,2I9CN@201174|Actinobacteria	201174|Actinobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
CMS3_k127_1809414_4	1234364.AMSF01000095_gene2617	5.253e-78	281.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RXCB@1236|Gammaproteobacteria,1X4WJ@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the AB hydrolase superfamily. MetX family	metXS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS3_k127_1809414_0	1121878.AUGL01000001_gene239	9.499e-160	534.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3939,iBWG_1329.BWG_3608,iECDH10B_1368.ECDH10B_4128,iECDH1ME8569_1439.ECDH1ME8569_3808,iETEC_1333.ETEC_4208,iEcDH1_1363.EcDH1_4046,iEcHS_1320.EcHS_A4172,iEcolC_1368.EcolC_4076,iJO1366.b3939,iJR904.b3939,iUMNK88_1353.UMNK88_4777,iUTI89_1310.UTI89_C4524,iY75_1357.Y75_RS17365	Cys_Met_Meta_PP
CMS3_k127_1809414_13	47716.JOFH01000021_gene4165	2.88e-05	53.0	COG1309@1|root,COG1309@2|Bacteria,2GYI1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1809414_5	748247.AZKH_4190	3.767e-53	211.0	COG4191@1|root,COG4191@2|Bacteria,1R3RN@1224|Proteobacteria,2VPMH@28216|Betaproteobacteria	28216|Betaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS3_k127_1809414_6	197221.22294269	1.786e-50	196.0	29IGX@1|root,305E4@2|Bacteria,1GCZY@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1809414_3	452637.Oter_3920	5.345e-108	385.0	COG0642@1|root,COG0784@1|root,COG3279@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3279@2|Bacteria,46TGZ@74201|Verrucomicrobia,3K7Q0@414999|Opitutae	414999|Opitutae	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_1809414_9	631362.Thi970DRAFT_03729	2.735e-12	79.0	COG1572@1|root,COG2911@1|root,COG3210@1|root,COG4625@1|root,COG4932@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria,1P8N9@1224|Proteobacteria,1T4WQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347
CMS3_k127_1809414_8	1122176.KB903609_gene5148	7.358e-24	119.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_1809414_1	1396141.BATP01000033_gene4252	1.226e-135	473.0	COG2312@1|root,COG2312@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
CMS3_k127_1809414_10	1396141.BATP01000007_gene5691	2.947e-09	71.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg,DUF4440,Erythro_esteras
CMS3_k127_1809414_7	246197.MXAN_6633	1.266e-43	183.0	28HUE@1|root,2Z815@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1809414_2	404589.Anae109_3304	1.229e-109	387.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42P16@68525|delta/epsilon subdivisions,2WMD4@28221|Deltaproteobacteria,2YXD8@29|Myxococcales	28221|Deltaproteobacteria	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
CMS3_k127_1809414_12	1123508.JH636450_gene7239	5.221e-06	56.0	2DM25@1|root,31E7N@2|Bacteria,2J3D6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1812841_1	1121921.KB898709_gene419	1.709e-08	67.0	COG4225@1|root,COG4225@2|Bacteria,1MU2J@1224|Proteobacteria,1RR65@1236|Gammaproteobacteria,2PN9M@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_88
CMS3_k127_1812841_0	290397.Adeh_4094	5.57e-55	196.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS3_k127_1812841_2	1304880.JAGB01000003_gene1258	0.000703	42.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	-	-	3.1.3.87	ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07394	RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Put_Phosphatase
CMS3_k127_1818538_0	338963.Pcar_0323	1.021e-56	215.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,43S7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS3_k127_1831277_14	1288963.ADIS_4241	1.407e-09	67.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_1831277_0	880070.Cycma_2445	6.681e-186	612.0	COG0591@1|root,COG3055@1|root,COG0591@2|Bacteria,COG3055@2|Bacteria,4NEN8@976|Bacteroidetes,47UXG@768503|Cytophagia	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	Kelch_1,Kelch_5,Kelch_6,SSF
CMS3_k127_1831277_10	1123242.JH636434_gene3895	2.736e-17	96.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_1831277_3	1210884.HG799473_gene14943	2.347e-92	321.0	COG1502@1|root,COG1502@2|Bacteria,2IYFI@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CMS3_k127_1831277_11	575540.Isop_2672	8.405e-15	89.0	COG0589@1|root,COG0589@2|Bacteria,2J0XB@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_1831277_8	1191523.MROS_2770	4.298e-31	128.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_1831277_1	243090.RB3348	2.757e-169	539.0	COG2942@1|root,COG2942@2|Bacteria,2J1EQ@203682|Planctomycetes	203682|Planctomycetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11,5.1.3.8	ko:K01787,ko:K16213	ko00520,map00520	-	R01207,R01445,R10810	RC00289,RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
CMS3_k127_1831277_15	886293.Sinac_5806	3.191e-08	66.0	COG1807@1|root,COG1807@2|Bacteria,2J1H1@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1831277_4	378806.STAUR_0277	6.503e-79	275.0	COG2367@1|root,COG2367@2|Bacteria,1Q2UC@1224|Proteobacteria,438GK@68525|delta/epsilon subdivisions,2X3RE@28221|Deltaproteobacteria,2YWXF@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
CMS3_k127_1831277_2	649638.Trad_2464	5.585e-99	340.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
CMS3_k127_1831277_6	324602.Caur_0649	7.195e-50	195.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_1831277_16	1168289.AJKI01000004_gene2956	0.0004953	53.0	COG1572@1|root,COG3291@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4PI1C@976|Bacteroidetes,2G1DF@200643|Bacteroidia,3XKWE@558415|Marinilabiliaceae	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_1831277_9	1027273.GZ77_17870	1.5e-27	115.0	COG1553@1|root,COG1553@2|Bacteria,1NDPA@1224|Proteobacteria,1SFY2@1236|Gammaproteobacteria,1XQIZ@135619|Oceanospirillales	135619|Oceanospirillales	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_1831277_5	1027273.GZ77_17875	2.669e-54	197.0	COG1553@1|root,COG1553@2|Bacteria,1NUU5@1224|Proteobacteria,1SNGR@1236|Gammaproteobacteria,1XPSW@135619|Oceanospirillales	135619|Oceanospirillales	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_1831277_7	118168.MC7420_2616	5.868e-42	157.0	2DZNU@1|root,32VEW@2|Bacteria,1G855@1117|Cyanobacteria	1117|Cyanobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_1831277_13	491916.RHECIAT_CH0002832	2.951e-10	74.0	COG0457@1|root,COG1629@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,COG4771@2|Bacteria,1RJUD@1224|Proteobacteria,2U2AY@28211|Alphaproteobacteria,4BA1D@82115|Rhizobiaceae	28211|Alphaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
CMS3_k127_1831277_12	575540.Isop_0068	1.847e-11	78.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1853350_3	2002.JOEQ01000020_gene7083	2.067e-15	88.0	COG3266@1|root,COG3266@2|Bacteria,2GQ3D@201174|Actinobacteria,4EK9A@85012|Streptosporangiales	201174|Actinobacteria	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
CMS3_k127_1853350_5	1236542.BALM01000002_gene814	5.574e-08	66.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,1RNU3@1236|Gammaproteobacteria,2QAT1@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_1853350_6	502025.Hoch_2739	1.877e-05	57.0	2C9M1@1|root,2ZSUM@2|Bacteria	502025.Hoch_2739|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1853350_0	326297.Sama_1905	0.0	1058.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2QA13@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrF	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS3_k127_1853350_1	935567.JAES01000023_gene2519	2.126e-68	248.0	COG0845@1|root,COG0845@2|Bacteria,1R8W0@1224|Proteobacteria,1S0GT@1236|Gammaproteobacteria,1X4V5@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS3_k127_1853350_2	575540.Isop_2652	1.746e-41	167.0	COG3828@1|root,COG3828@2|Bacteria,2IX0E@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS3_k127_1853350_4	452637.Oter_3566	4.046e-09	68.0	COG2133@1|root,COG2133@2|Bacteria,46Z7C@74201|Verrucomicrobia,3K9RA@414999|Opitutae	414999|Opitutae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_1867663_25	391625.PPSIR1_02678	0.0003634	47.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
CMS3_k127_1867663_13	867845.KI911784_gene2277	1.381e-54	211.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_1867663_14	530564.Psta_3753	8.933e-29	122.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1867663_0	335543.Sfum_3546	1.84e-301	947.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,1R42U@1224|Proteobacteria,42UMM@68525|delta/epsilon subdivisions,2WQVW@28221|Deltaproteobacteria,2MS0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
CMS3_k127_1867663_20	502025.Hoch_3311	4.952e-10	74.0	COG0793@1|root,COG0793@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_1867663_26	1297742.A176_05903	0.000628	53.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K14475,ko:K20276	ko02024,ko05143,map02024,map05143	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,RCC1_2
CMS3_k127_1867663_16	1448389.BAVQ01000027_gene1064	1.109e-20	105.0	COG3012@1|root,COG3012@2|Bacteria,2GMVI@201174|Actinobacteria	201174|Actinobacteria	S	PFAM plasmid pRiA4b ORF-3 family protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CMS3_k127_1867663_23	326423.RBAM_003020	0.0001029	54.0	COG1405@1|root,COG3012@1|root,COG1405@2|Bacteria,COG3012@2|Bacteria,1V8NE@1239|Firmicutes,4HK5V@91061|Bacilli,1ZE7P@1386|Bacillus	91061|Bacilli	K	SEC-C motif	yccF	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	HTH_psq,SEC-C
CMS3_k127_1867663_6	489825.LYNGBM3L_21180	1.415e-142	462.0	COG0438@1|root,COG0438@2|Bacteria,1GCX5@1117|Cyanobacteria	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1867663_5	489825.LYNGBM3L_21180	6.84e-143	470.0	COG0438@1|root,COG0438@2|Bacteria,1GCX5@1117|Cyanobacteria	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1867663_4	335543.Sfum_3550	1.218e-144	472.0	COG0438@1|root,COG0438@2|Bacteria,1NTNW@1224|Proteobacteria,42Z8E@68525|delta/epsilon subdivisions,2WTUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1867663_17	886293.Sinac_4403	8.159e-17	95.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
CMS3_k127_1867663_1	251229.Chro_0877	2.608e-180	611.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,3VINJ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1867663_7	671143.DAMO_1946	3.879e-121	420.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CMS3_k127_1867663_12	1463934.JOCF01000038_gene2229	3.456e-72	273.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_1867663_18	1121013.P873_12970	1.181e-15	89.0	COG1309@1|root,COG1309@2|Bacteria,1RCI9@1224|Proteobacteria,1S3KX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_1867663_2	595460.RRSWK_03283	1.439e-177	602.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2J0UK@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid permease	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
CMS3_k127_1867663_3	886293.Sinac_5718	2.559e-147	513.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CMS3_k127_1867663_24	1288494.EBAPG3_2670	0.0001212	54.0	COG2010@1|root,COG2010@2|Bacteria,1NE41@1224|Proteobacteria,2WEJ6@28216|Betaproteobacteria,373D7@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_1867663_10	388051.AUFE01000004_gene894	8.287e-94	335.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,2W9V7@28216|Betaproteobacteria,1K54Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_1867663_9	314230.DSM3645_10617	5.199e-101	360.0	COG3420@1|root,COG3420@2|Bacteria,2J2DV@203682|Planctomycetes	203682|Planctomycetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_1867663_22	1089549.AZUQ01000001_gene2642	1.927e-06	60.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4EYJ0@85014|Glycomycetales	201174|Actinobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
CMS3_k127_1867663_21	35754.JNYJ01000078_gene7849	2.209e-09	62.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DDFA@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1867663_8	234267.Acid_3938	2.029e-113	400.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_1867663_11	251221.35214774	2.675e-88	323.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
CMS3_k127_1867663_19	595460.RRSWK_03057	2.069e-11	76.0	COG1595@1|root,COG1595@2|Bacteria,2IZJK@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_1867663_15	530564.Psta_4044	9.373e-23	106.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_187629_2	1121904.ARBP01000003_gene6415	2.785e-176	588.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_187629_6	83219.PM02_05110	3.118e-81	286.0	COG0662@1|root,COG1917@1|root,COG0662@2|Bacteria,COG1917@2|Bacteria,1NNBT@1224|Proteobacteria,2U1PR@28211|Alphaproteobacteria,3ZVCJ@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_187629_18	1242864.D187_008608	5.294e-18	99.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_187629_14	1128421.JAGA01000003_gene3091	2.389e-25	124.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_187629_16	479434.Sthe_0323	2.577e-19	104.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS3_k127_187629_21	65393.PCC7424_1913	1.124e-09	71.0	COG1807@1|root,COG1807@2|Bacteria,1G424@1117|Cyanobacteria,3KHC9@43988|Cyanothece	1117|Cyanobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_187629_13	411464.DESPIG_02421	2.341e-25	113.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,42VNC@68525|delta/epsilon subdivisions,2WRIM@28221|Deltaproteobacteria,2MD5H@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS3_k127_187629_19	756272.Plabr_0025	2.052e-14	79.0	COG0594@1|root,COG0594@2|Bacteria,2J0QW@203682|Planctomycetes	203682|Planctomycetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS3_k127_187629_26	909663.KI867150_gene2934	5.446e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MR1G@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
CMS3_k127_187629_3	314230.DSM3645_21809	6.713e-171	581.0	COG0334@1|root,COG0334@2|Bacteria,2IWWC@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_187629_9	1118054.CAGW01000055_gene2578	4.918e-46	181.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,26R13@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmCD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS3_k127_187629_5	221288.JH992901_gene3259	3.142e-87	299.0	COG0500@1|root,COG2226@2|Bacteria,1GK6S@1117|Cyanobacteria,1JKHT@1189|Stigonemataceae	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_187629_22	1254432.SCE1572_02425	4.335e-09	68.0	COG1716@1|root,COG1716@2|Bacteria,1Q2GC@1224|Proteobacteria,4382T@68525|delta/epsilon subdivisions,2X0C6@28221|Deltaproteobacteria,2YVG7@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_187629_8	290397.Adeh_0162	1.439e-52	205.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2WM6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
CMS3_k127_187629_10	314230.DSM3645_29606	1.407e-44	176.0	COG0105@1|root,COG0105@2|Bacteria,2IZQ6@203682|Planctomycetes	203682|Planctomycetes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS3_k127_187629_17	1121929.KB898666_gene2635	3.955e-19	98.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,470N1@74385|Gracilibacillus	91061|Bacilli	K	ECF sigma factor	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_187629_4	1232410.KI421428_gene1165	2.163e-140	468.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,43S1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS3_k127_187629_12	1191523.MROS_0276	2.432e-34	145.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS3_k127_187629_25	1122179.KB890422_gene2212	4.824e-05	51.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1ITY0@117747|Sphingobacteriia	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS3_k127_187629_23	1123257.AUFV01000011_gene3118	5.087e-09	64.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1X60B@135614|Xanthomonadales	135614|Xanthomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS3_k127_187629_15	1033739.CAEU01000009_gene2047	2.168e-20	97.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,26FN7@186818|Planococcaceae	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS3_k127_187629_0	1340493.JNIF01000004_gene349	3.789e-189	604.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS3_k127_187629_7	517418.Ctha_0874	1.734e-55	207.0	COG0224@1|root,COG0224@2|Bacteria,1FD78@1090|Chlorobi	1090|Chlorobi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS3_k127_187629_1	706587.Desti_3705	7.563e-189	617.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2MQ73@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS3_k127_187629_20	868595.Desca_2628	3.42e-14	82.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,2629N@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
CMS3_k127_1895068_21	1396418.BATQ01000117_gene4605	1.232e-70	267.0	COG2755@1|root,COG4409@1|root,COG2755@2|Bacteria,COG4409@2|Bacteria,46TCP@74201|Verrucomicrobia,2IWKC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_1895068_4	313628.LNTAR_22434	9.135e-160	515.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_1895068_15	215803.DB30_7770	6.282e-106	365.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS3_k127_1895068_56	1192124.LIG30_4752	1.734e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_14,TPR_16,TPR_2,TPR_4,TPR_8
CMS3_k127_1895068_36	1396418.BATQ01000051_gene59	3.294e-34	148.0	COG3203@1|root,COG3203@2|Bacteria,46SY8@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS3_k127_1895068_59	225937.HP15_342	9.109e-05	52.0	COG1595@1|root,COG1595@2|Bacteria,1N748@1224|Proteobacteria,1SEDH@1236|Gammaproteobacteria,46CF3@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1895068_11	595460.RRSWK_03954	3.066e-132	441.0	COG2730@1|root,COG2730@2|Bacteria,2IWW8@203682|Planctomycetes	203682|Planctomycetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS3_k127_1895068_43	1234364.AMSF01000037_gene123	1.099e-26	125.0	COG1807@1|root,COG1807@2|Bacteria,1N49T@1224|Proteobacteria,1T1N5@1236|Gammaproteobacteria,1X4WF@135614|Xanthomonadales	135614|Xanthomonadales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_1895068_47	439235.Dalk_0490	1.048e-17	97.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TonB_C
CMS3_k127_1895068_52	1087481.AGFX01000016_gene2867	5.711e-09	69.0	COG1225@1|root,COG1225@2|Bacteria,1V24A@1239|Firmicutes,4HFUX@91061|Bacilli,26R0T@186822|Paenibacillaceae	91061|Bacilli	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1895068_29	290397.Adeh_1709	3.315e-44	185.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUMV@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1895068_50	246197.MXAN_0002	3.451e-15	91.0	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_1895068_27	713587.THITH_13720	6.522e-46	179.0	COG0223@1|root,COG0223@2|Bacteria	2|Bacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	2.1.2.2,2.1.2.9	ko:K00604,ko:K11175	ko00230,ko00670,ko00970,ko01100,ko01110,ko01130,map00230,map00670,map00970,map01100,map01110,map01130	M00048	R03940,R04325,R04326	RC00026,RC00165,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS3_k127_1895068_14	383372.Rcas_3193	8.9e-114	379.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,377XY@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_1895068_20	575540.Isop_1099	3.415e-74	265.0	COG0845@1|root,COG0845@2|Bacteria,2J330@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS3_k127_1895068_0	335543.Sfum_3380	0.0	1049.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,2MQA5@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_1895068_28	756272.Plabr_2560	2.639e-45	189.0	COG0515@1|root,COG0515@2|Bacteria,2IYFB@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_1895068_39	330214.NIDE4245	2.922e-31	133.0	COG1595@1|root,COG1595@2|Bacteria,3J1A1@40117|Nitrospirae	40117|Nitrospirae	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1895068_46	1340493.JNIF01000003_gene4568	3.706e-18	95.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K04786,ko:K12240,ko:K13613,ko:K15677	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	ADH_N,ADH_zinc_N,AMP-binding,Acyl_transf_1,Condensation,Glyoxalase_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,NUDIX,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
CMS3_k127_1895068_44	326424.FRAAL2585	2.061e-21	109.0	COG0535@1|root,COG0535@2|Bacteria,2GTTW@201174|Actinobacteria	201174|Actinobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_1895068_34	929712.KI912613_gene3509	4.2e-37	157.0	COG0500@1|root,COG2226@2|Bacteria,2HAB1@201174|Actinobacteria	2|Bacteria	Q	Methyltransferase domain	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Methyltransf_11
CMS3_k127_1895068_48	445972.ANACOL_00884	4.356e-17	96.0	COG0535@1|root,COG0535@2|Bacteria,1VBU3@1239|Firmicutes,25M2V@186801|Clostridia,3WM5Z@541000|Ruminococcaceae	186801|Clostridia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_1895068_16	1265502.KB905951_gene847	1.165e-90	308.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2VJYK@28216|Betaproteobacteria,4ABHP@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	baeB	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_1895068_10	886293.Sinac_0026	1.621e-134	443.0	COG0673@1|root,COG0673@2|Bacteria,2IX6I@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_1895068_18	314230.DSM3645_29356	1.371e-81	281.0	COG0363@1|root,COG0363@2|Bacteria,2IYJ5@203682|Planctomycetes	203682|Planctomycetes	G	6-phosphogluconolactonase glucosamine-6-phosphate isomerase deaminase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
CMS3_k127_1895068_55	595460.RRSWK_07091	1.111e-05	56.0	COG1595@1|root,COG1595@2|Bacteria,2IZMI@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_1895068_19	1210884.HG799462_gene8934	2.632e-76	291.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	2|Bacteria	KLT	Protein kinase domain	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,WD40
CMS3_k127_1895068_32	1121403.AUCV01000068_gene2206	5.828e-42	176.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,42QIQ@68525|delta/epsilon subdivisions,2WM7F@28221|Deltaproteobacteria,2MJ1M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_1895068_25	479432.Sros_1152	7.546e-48	188.0	COG2265@1|root,COG2265@2|Bacteria,2GK97@201174|Actinobacteria,4EH8H@85012|Streptosporangiales	201174|Actinobacteria	J	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_15,Methyltransf_25
CMS3_k127_1895068_24	502025.Hoch_0068	2.661e-53	215.0	COG3227@1|root,COG3227@2|Bacteria,1Q6DC@1224|Proteobacteria,432XR@68525|delta/epsilon subdivisions,2WYJ7@28221|Deltaproteobacteria,2Z34H@29|Myxococcales	28221|Deltaproteobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1895068_35	313628.LNTAR_07996	1.319e-34	153.0	COG1621@1|root,COG4886@1|root,COG1621@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
CMS3_k127_1895068_8	1403819.BATR01000045_gene1313	1.319e-140	477.0	COG4102@1|root,COG4102@2|Bacteria,46U0B@74201|Verrucomicrobia,2IU14@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_1895068_12	1123242.JH636435_gene2908	2.262e-122	419.0	COG2319@1|root,COG2319@2|Bacteria,2IZGW@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
CMS3_k127_1895068_54	344747.PM8797T_29323	3.273e-07	61.0	2EB2R@1|root,3353H@2|Bacteria,2J0PP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1895068_40	886293.Sinac_5989	5.678e-31	128.0	COG1595@1|root,COG1595@2|Bacteria,2J0H3@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_1895068_45	502025.Hoch_6691	7.26e-20	96.0	COG2010@1|root,COG2010@2|Bacteria,1PEGU@1224|Proteobacteria,434ZM@68525|delta/epsilon subdivisions,2X93H@28221|Deltaproteobacteria,2Z1PW@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1895068_9	489825.LYNGBM3L_21180	2.228e-135	460.0	COG0438@1|root,COG0438@2|Bacteria,1GCX5@1117|Cyanobacteria	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1895068_5	489825.LYNGBM3L_21190	1.422e-156	514.0	COG0438@1|root,COG0438@2|Bacteria,1GC2Y@1117|Cyanobacteria	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1895068_38	13690.CP98_04528	8.747e-33	137.0	COG0500@1|root,COG0726@1|root,COG1215@1|root,COG0500@2|Bacteria,COG0726@2|Bacteria,COG1215@2|Bacteria,1RIMV@1224|Proteobacteria,2TW81@28211|Alphaproteobacteria,2KECZ@204457|Sphingomonadales	204457|Sphingomonadales	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	NodS
CMS3_k127_1895068_30	886293.Sinac_4407	2.841e-43	183.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_1895068_6	1173026.Glo7428_0931	1.639e-152	515.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_1895068_41	1249627.D779_0013	6.787e-30	131.0	COG2227@1|root,COG2227@2|Bacteria,1RAW1@1224|Proteobacteria,1S3J6@1236|Gammaproteobacteria,1X1EF@135613|Chromatiales	135613|Chromatiales	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS3_k127_1895068_7	682795.AciX8_2616	2.838e-142	462.0	COG0304@1|root,COG0304@2|Bacteria,3Y2NT@57723|Acidobacteria,2JMBR@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_1895068_51	1449126.JQKL01000022_gene142	2.642e-10	66.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,269R3@186813|unclassified Clostridiales	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_1895068_1	335543.Sfum_3546	3.756e-309	978.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,1R42U@1224|Proteobacteria,42UMM@68525|delta/epsilon subdivisions,2WQVW@28221|Deltaproteobacteria,2MS0N@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glycos_transf_2
CMS3_k127_1895068_37	1123242.JH636435_gene2795	2.54e-33	140.0	COG1595@1|root,COG1595@2|Bacteria,2J3CV@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1895068_13	67593.Physo157244	3.746e-116	383.0	COG1250@1|root,KOG2304@2759|Eukaryota,3Q7F0@4776|Peronosporales	4776|Peronosporales	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.35	ko:K00022	ko00062,ko00071,ko00280,ko00281,ko00310,ko00380,ko00650,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00062,map00071,map00280,map00281,map00310,map00380,map00650,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00085,M00087	R01778,R01975,R04203,R04737,R04739,R04741,R04743,R04745,R04748,R05066,R06941,R08094	RC00029,RC00099,RC00103,RC00117,RC00241,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_1895068_33	1396141.BATP01000032_gene4375	6.123e-39	167.0	COG4233@1|root,COG4233@2|Bacteria,46YXH@74201|Verrucomicrobia,2IVVA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CMS3_k127_1895068_2	344747.PM8797T_27312	1.187e-207	670.0	COG3119@1|root,COG3119@2|Bacteria,2IYB8@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_1895068_17	344747.PM8797T_28994	1.49e-82	286.0	COG3622@1|root,COG3622@2|Bacteria,2IY93@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_1895068_31	234267.Acid_6442	4.803e-42	173.0	COG0177@1|root,COG0177@2|Bacteria,3Y8R4@57723|Acidobacteria	57723|Acidobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1895068_53	1173020.Cha6605_0233	1.597e-08	66.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_1895068_3	526225.Gobs_4986	1.394e-192	608.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4ES44@85013|Frankiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase	fdhA	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,AlaDh_PNT_C
CMS3_k127_1895068_49	1121405.dsmv_3249	1.963e-16	86.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2MKG1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_1895068_42	518766.Rmar_1723	3.112e-27	128.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,4NDX5@976|Bacteroidetes,1FIMZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Helix-hairpin-helix domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8
CMS3_k127_1895068_23	861299.J421_5989	8.276e-56	216.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_1895068_22	391625.PPSIR1_13023	3.235e-70	248.0	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,42UPB@68525|delta/epsilon subdivisions,2WS1K@28221|Deltaproteobacteria,2YVR9@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_1895068_26	575540.Isop_0068	7.567e-47	193.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1895068_58	448385.sce1597	6.968e-05	56.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,2YWMA@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CMS3_k127_1898588_2	1173028.ANKO01000199_gene3562	1.082e-32	146.0	COG2027@1|root,COG2027@2|Bacteria,1G1K9@1117|Cyanobacteria,1H702@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS3_k127_1898588_1	1183438.GKIL_2653	4.637e-56	222.0	COG0483@1|root,COG0483@2|Bacteria,1G0GD@1117|Cyanobacteria	1117|Cyanobacteria	G	Inositol monophosphatase	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS3_k127_1898588_0	522306.CAP2UW1_1285	1.984e-209	676.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2WHVC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
CMS3_k127_1899081_2	1123508.JH636439_gene519	3.081e-44	168.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_1899081_0	589865.DaAHT2_2643	7.486e-129	441.0	COG3639@1|root,COG3639@2|Bacteria,1N3HU@1224|Proteobacteria,43AKI@68525|delta/epsilon subdivisions,2WQEI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
CMS3_k127_1899081_1	305700.B447_05690	6.289e-83	282.0	COG3638@1|root,COG3638@2|Bacteria,1MXYA@1224|Proteobacteria,2VM4F@28216|Betaproteobacteria,2KZ2G@206389|Rhodocyclales	206389|Rhodocyclales	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
CMS3_k127_1912057_0	1340493.JNIF01000003_gene2699	9.566e-54	209.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,3Y2Y4@57723|Acidobacteria	57723|Acidobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	1.1.1.25,4.2.1.10	ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_dh_N
CMS3_k127_1912057_1	1449068.JMLQ01000003_gene2239	2.615e-16	93.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria,4FYM1@85025|Nocardiaceae	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS3_k127_1912057_3	1286631.X805_30560	0.00013	56.0	2E3WQ@1|root,32YTW@2|Bacteria,1NDH4@1224|Proteobacteria,2VWRA@28216|Betaproteobacteria,1KNYS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1912057_2	1121091.AUMP01000054_gene3367	5.08e-06	54.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1916088_6	1283300.ATXB01000002_gene2888	1.42e-41	168.0	2DP87@1|root,330Z8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1916088_3	401053.AciPR4_2793	1.223e-69	268.0	COG2423@1|root,COG2423@2|Bacteria,3Y82U@57723|Acidobacteria,2JNQR@204432|Acidobacteriia	204432|Acidobacteriia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS3_k127_1916088_7	521674.Plim_0306	1.74e-29	136.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
CMS3_k127_1916088_8	344747.PM8797T_24886	9.993e-21	104.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	CAP,HemolysinCabind,Peptidase_M10_C,VCBS
CMS3_k127_1916088_5	644966.Tmar_0739	1.239e-47	184.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
CMS3_k127_1916088_4	1267534.KB906754_gene3377	2.443e-64	252.0	COG0312@1|root,COG0312@2|Bacteria,3Y3B9@57723|Acidobacteria,2JI5P@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_1916088_0	234267.Acid_5819	8.122e-156	511.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
CMS3_k127_1916088_1	1396418.BATQ01000030_gene5614	1.913e-92	318.0	COG0577@1|root,COG0577@2|Bacteria,46TQS@74201|Verrucomicrobia,2IWMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_1916088_2	518766.Rmar_0068	2.232e-70	250.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1FIVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_1916088_9	497964.CfE428DRAFT_5399	2.995e-11	70.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS3_k127_1931637_4	1122963.AUHB01000006_gene2514	8.028e-29	127.0	COG1028@1|root,COG1028@2|Bacteria,1N4Z9@1224|Proteobacteria,2UE0R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_1931637_2	1267534.KB906754_gene2733	8.378e-56	215.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS3_k127_1931637_5	237368.SCABRO_02406	3.335e-26	116.0	COG3880@1|root,COG3880@2|Bacteria,2J09E@203682|Planctomycetes	203682|Planctomycetes	S	protein with conserved CXXC pairs	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
CMS3_k127_1931637_1	575540.Isop_3468	6.768e-89	312.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
CMS3_k127_1931637_0	986075.CathTA2_0959	3.991e-302	955.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS3_k127_1931637_3	555778.Hneap_2088	1.408e-55	211.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales	135613|Chromatiales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS3_k127_1956434_26	756272.Plabr_0671	4.922e-07	60.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2IYCQ@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
CMS3_k127_1956434_16	1304284.L21TH_0978	1.153e-35	141.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,36JJ4@31979|Clostridiaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS3_k127_1956434_7	420246.GTNG_1054	1.81e-73	254.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1WE2C@129337|Geobacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS3_k127_1956434_14	667014.Thein_0397	1.951e-43	166.0	COG0307@1|root,COG0307@2|Bacteria,2GGV7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS3_k127_1956434_21	517418.Ctha_1573	6.902e-15	87.0	COG1463@1|root,COG1463@2|Bacteria,1FDVW@1090|Chlorobi	1090|Chlorobi	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_1956434_10	247490.KSU1_C0177	8.495e-57	221.0	COG1127@1|root,COG1127@2|Bacteria,2IXBY@203682|Planctomycetes	203682|Planctomycetes	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_1956434_15	243231.GSU1900	3.223e-43	168.0	COG0767@1|root,COG0767@2|Bacteria,1RHNJ@1224|Proteobacteria,42SNW@68525|delta/epsilon subdivisions,2WPKT@28221|Deltaproteobacteria,43T2D@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_1956434_18	1232410.KI421421_gene3416	2.648e-26	124.0	COG3170@1|root,COG3170@2|Bacteria,1MY6X@1224|Proteobacteria,42TBE@68525|delta/epsilon subdivisions,2WPBV@28221|Deltaproteobacteria,43U5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1956434_4	237368.SCABRO_01228	8.9e-111	367.0	COG0180@1|root,COG0180@2|Bacteria,2IWRB@203682|Planctomycetes	203682|Planctomycetes	J	Tryptophanyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1b
CMS3_k127_1956434_25	1297569.MESS2_790082	6.257e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_10,TPR_11,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_1956434_19	247490.KSU1_B0124	2.754e-23	103.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_1956434_3	1197130.BAFM01000025_gene2997	2.014e-143	470.0	COG0626@1|root,arCOG00060@2157|Archaea,2XT98@28890|Euryarchaeota,23S23@183963|Halobacteria	183963|Halobacteria	E	COG0626 Cystathionine beta-lyases cystathionine gamma-synthases	metB	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CMS3_k127_1956434_5	643648.Slip_1717	8.997e-97	344.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,42JRU@68298|Syntrophomonadaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
CMS3_k127_1956434_23	589865.DaAHT2_1538	1.17e-10	70.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WM56@28221|Deltaproteobacteria,2MHKW@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS3_k127_1956434_6	429009.Adeg_0657	3.389e-95	332.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,42F8N@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS3_k127_1956434_22	661367.LLO_0471	5.396e-12	69.0	2EG8N@1|root,33A0G@2|Bacteria,1NHU3@1224|Proteobacteria,1SGMX@1236|Gammaproteobacteria,1JGA4@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1956434_2	314230.DSM3645_09477	1.358e-194	614.0	COG0050@1|root,COG0050@2|Bacteria,2IXC2@203682|Planctomycetes	203682|Planctomycetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS3_k127_1956434_24	575540.Isop_0111	6.148e-09	63.0	COG0690@1|root,COG0690@2|Bacteria,2J0E7@203682|Planctomycetes	203682|Planctomycetes	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS3_k127_1956434_13	247490.KSU1_C1196	2.524e-47	177.0	COG0250@1|root,COG0250@2|Bacteria,2IZ9N@203682|Planctomycetes	203682|Planctomycetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS3_k127_1956434_11	161156.JQKW01000011_gene915	5.756e-52	186.0	COG0080@1|root,COG0080@2|Bacteria,2GHUT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS3_k127_1956434_8	247490.KSU1_C1198	3.187e-73	254.0	COG0081@1|root,COG0081@2|Bacteria,2IYQK@203682|Planctomycetes	203682|Planctomycetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS3_k127_1956434_20	1313304.CALK_2102	5.461e-22	102.0	COG0244@1|root,COG0244@2|Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02864,ko:K02935	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS3_k127_1956434_17	1121334.KB911074_gene2485	1.777e-33	134.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS3_k127_1956434_1	344747.PM8797T_12151	0.0	1527.0	COG0085@1|root,COG0085@2|Bacteria,2IXVZ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS3_k127_1956434_0	886293.Sinac_0499	0.0	1848.0	COG0086@1|root,COG0086@2|Bacteria,2IXGN@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS3_k127_1956434_9	1125863.JAFN01000001_gene3290	3.599e-59	208.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS3_k127_1956434_12	381764.Fnod_1142	6.038e-52	187.0	COG0049@1|root,COG0049@2|Bacteria,2GCUI@200918|Thermotogae	200918|Thermotogae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS3_k127_1956708_1	1123325.JHUV01000008_gene880	1.587e-12	71.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS3_k127_1956708_0	1125863.JAFN01000001_gene443	2.696e-92	321.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS3_k127_1959287_0	344747.PM8797T_30434	1.814e-161	532.0	COG1914@1|root,COG1914@2|Bacteria,2IYDP@203682|Planctomycetes	203682|Planctomycetes	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS3_k127_1959287_1	196490.AUEZ01000036_gene6081	6.691e-29	127.0	COG3828@1|root,COG3828@2|Bacteria,1R5XA@1224|Proteobacteria,2U51F@28211|Alphaproteobacteria,3K5VQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	GSDH,ThuA
CMS3_k127_1973532_17	760192.Halhy_1129	4.266e-35	153.0	COG1572@1|root,COG1572@2|Bacteria,4NYS6@976|Bacteroidetes,1IZ9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1973532_15	1047013.AQSP01000101_gene615	2.694e-41	165.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Gp58
CMS3_k127_1973532_25	1210884.HG799464_gene10957	2.706e-10	72.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_1973532_24	1218352.B597_004440	4.266e-13	70.0	COG3012@1|root,COG3012@2|Bacteria,1NH4U@1224|Proteobacteria,1SHZB@1236|Gammaproteobacteria,1Z3IM@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Preprotein translocase subunit SecA (ATPase, RNA helicase)	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
CMS3_k127_1973532_12	530564.Psta_2884	5.924e-52	213.0	COG0810@1|root,COG1657@1|root,COG0810@2|Bacteria,COG1657@2|Bacteria,2IXNC@203682|Planctomycetes	203682|Planctomycetes	IM	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1973532_30	1423321.AS29_16820	2.596e-05	59.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HDFU@91061|Bacilli,1ZPV1@1386|Bacillus	91061|Bacilli	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
CMS3_k127_1973532_4	756272.Plabr_2754	1.431e-174	554.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_1973532_7	240016.ABIZ01000001_gene2846	5.41e-136	439.0	COG1082@1|root,COG1082@2|Bacteria,46XDK@74201|Verrucomicrobia,2IVJT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_1973532_5	1403819.BATR01000130_gene4650	2.972e-141	481.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,46TRI@74201|Verrucomicrobia,2IU45@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
CMS3_k127_1973532_1	1123070.KB899255_gene1386	6.333e-226	714.0	COG1461@1|root,COG2376@1|root,COG1461@2|Bacteria,COG2376@2|Bacteria,46V9H@74201|Verrucomicrobia,2IVDJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Dak1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Dak1
CMS3_k127_1973532_29	1297742.A176_03344	7.862e-06	60.0	COG1196@1|root,COG1196@2|Bacteria,1RJS1@1224|Proteobacteria,43236@68525|delta/epsilon subdivisions,2WWXG@28221|Deltaproteobacteria,2YV0I@29|Myxococcales	1224|Proteobacteria	D	Domain of unknown function (DUF4150)	-	-	-	-	-	-	-	-	-	-	-	-	AHH,DUF4150
CMS3_k127_1973532_16	309803.CTN_0094	2.894e-41	176.0	COG0265@1|root,COG0265@2|Bacteria,2GCIH@200918|Thermotogae	200918|Thermotogae	M	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_1973532_21	595460.RRSWK_02799	2.305e-21	108.0	COG0589@1|root,COG0589@2|Bacteria,2J48V@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_1973532_18	1286093.C266_10771	3.679e-34	151.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,1K01Z@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_1973532_8	1173028.ANKO01000174_gene2711	7.557e-136	445.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1HEHF@1150|Oscillatoriales	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1973532_9	378806.STAUR_4929	3.501e-83	302.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
CMS3_k127_1973532_28	575540.Isop_0069	7.276e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,2J0K1@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
CMS3_k127_1973532_11	1210884.HG799471_gene14563	2.254e-59	234.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_1973532_14	404589.Anae109_1544	2.936e-42	174.0	COG3791@1|root,COG4974@1|root,COG3791@2|Bacteria,COG4974@2|Bacteria,1MZES@1224|Proteobacteria,42TG9@68525|delta/epsilon subdivisions,2WQ2N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CMS3_k127_1973532_26	1235797.C816_02330	1.061e-09	72.0	COG1595@1|root,COG1595@2|Bacteria,1VB8F@1239|Firmicutes,24PH6@186801|Clostridia,2N7CP@216572|Oscillospiraceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_1973532_13	322710.Avin_15530	1.394e-48	195.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,1RNWH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cusR	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_1973532_19	396588.Tgr7_1209	3.953e-28	133.0	COG5002@1|root,COG5002@2|Bacteria,1QTSA@1224|Proteobacteria,1T1PH@1236|Gammaproteobacteria,1X2QW@135613|Chromatiales	135613|Chromatiales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07644,ko:K07645	ko02020,ko02024,map02020,map02024	M00452,M00453,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
CMS3_k127_1973532_10	396588.Tgr7_0552	4.334e-67	246.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WWAK@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS3_k127_1973532_23	84531.JMTZ01000019_gene3972	5.819e-15	81.0	COG0526@1|root,COG0526@2|Bacteria,1NCXZ@1224|Proteobacteria,1RZ3D@1236|Gammaproteobacteria,1XCAB@135614|Xanthomonadales	135614|Xanthomonadales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_1973532_20	1189619.pgond44_04660	2.398e-22	111.0	COG2067@1|root,COG2067@2|Bacteria,4NG1B@976|Bacteroidetes,1HY7J@117743|Flavobacteriia,4C46K@83612|Psychroflexus	976|Bacteroidetes	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CMS3_k127_1973532_31	203122.Sde_3552	3.749e-05	51.0	2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,468BH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CMS3_k127_1973532_32	1144275.COCOR_03802	0.0003624	53.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K12516	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.5.5	-	-	CarboxypepD_reg,SdrD_B
CMS3_k127_1973532_2	1144275.COCOR_01140	1.184e-177	591.0	COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	otsAB	-	2.4.1.15,2.4.1.347,3.1.3.12	ko:K00697,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,S6PP,Trehalose_PPase
CMS3_k127_1973532_3	468059.AUHA01000004_gene2228	8.441e-177	571.0	COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,1IP3V@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 15	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
CMS3_k127_1973532_0	1396418.BATQ01000141_gene3343	3.982e-282	889.0	COG4946@1|root,COG4946@2|Bacteria,46TXN@74201|Verrucomicrobia,2IV9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1973532_6	1317122.ATO12_10855	1.935e-138	466.0	COG3119@1|root,COG3227@1|root,COG3119@2|Bacteria,COG3227@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,2YGJN@290174|Aquimarina	976|Bacteroidetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Laminin_G_3,Sulfatase
CMS3_k127_1973532_27	926550.CLDAP_15280	3.549e-09	71.0	COG0793@1|root,COG3468@1|root,COG0793@2|Bacteria,COG3468@2|Bacteria,2G7PQ@200795|Chloroflexi	200795|Chloroflexi	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS3_k127_1985004_0	344747.PM8797T_09194	1.172e-110	373.0	COG0591@1|root,COG0591@2|Bacteria,2J2PM@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS3_k127_1985004_1	502025.Hoch_3486	9.933e-05	52.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
CMS3_k127_2003459_4	391625.PPSIR1_37209	5.075e-124	407.0	COG3608@1|root,COG3608@2|Bacteria,1QUH0@1224|Proteobacteria	1224|Proteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,Peptidase_M14
CMS3_k127_2003459_2	595460.RRSWK_01422	2.181e-201	638.0	COG3119@1|root,COG3119@2|Bacteria,2J26B@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_2003459_11	497965.Cyan7822_2709	5.579e-40	156.0	COG4067@1|root,COG4067@2|Bacteria,1G6KI@1117|Cyanobacteria,3KI1C@43988|Cyanothece	1117|Cyanobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS3_k127_2003459_3	1229172.JQFA01000005_gene120	1.085e-142	466.0	COG0189@1|root,COG0189@2|Bacteria,1G0DT@1117|Cyanobacteria,1H6ZT@1150|Oscillatoriales	1117|Cyanobacteria	F	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,Zn_protease
CMS3_k127_2003459_6	118168.MC7420_5448	1.53e-107	359.0	COG3608@1|root,COG3608@2|Bacteria,1G167@1117|Cyanobacteria,1H7T8@1150|Oscillatoriales	1117|Cyanobacteria	S	Succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS3_k127_2003459_8	1122599.AUGR01000004_gene2072	1.292e-91	316.0	COG0501@1|root,COG0501@2|Bacteria,1NG7Y@1224|Proteobacteria	1224|Proteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TerB
CMS3_k127_2003459_5	1278307.KB906976_gene1581	4.189e-116	391.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
CMS3_k127_2003459_10	1403819.BATR01000131_gene4676	3.43e-42	178.0	COG1082@1|root,COG3386@1|root,COG1082@2|Bacteria,COG3386@2|Bacteria,46Z3P@74201|Verrucomicrobia,2IUKA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Arylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,SGL
CMS3_k127_2003459_9	700598.Niako_0700	7.051e-61	237.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,1IWFP@117747|Sphingobacteriia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_2003459_7	314230.DSM3645_26354	4.561e-96	345.0	COG3828@1|root,COG3828@2|Bacteria,2IY8Q@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS3_k127_2003459_0	1121920.AUAU01000001_gene2279	0.0	1149.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_2003459_1	452637.Oter_3293	2.114e-216	685.0	COG0281@1|root,COG0281@2|Bacteria,46UI4@74201|Verrucomicrobia,3K7KY@414999|Opitutae	414999|Opitutae	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
CMS3_k127_2003459_13	1121448.DGI_2677	1.205e-17	98.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2MBT4@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_2003459_14	530564.Psta_1360	3.225e-07	62.0	COG1657@1|root,COG1657@2|Bacteria,2IX8J@203682|Planctomycetes	203682|Planctomycetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2003459_12	344747.PM8797T_13685	1.015e-25	115.0	COG0845@1|root,COG0845@2|Bacteria,2IYMS@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_2005158_2	314230.DSM3645_09102	5.3e-123	422.0	COG1530@1|root,COG1530@2|Bacteria,2IWSS@203682|Planctomycetes	203682|Planctomycetes	J	TIGRFAM ribonuclease, Rne Rng family	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS3_k127_2005158_24	1298593.TOL_3238	1.047e-37	162.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1XHZK@135619|Oceanospirillales	135619|Oceanospirillales	U	Type II and III secretion system protein	pilQ	-	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS3_k127_2005158_41	237368.SCABRO_02114	8.418e-06	55.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
CMS3_k127_2005158_27	1177181.T9A_00700	2.971e-34	147.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1XH3V@135619|Oceanospirillales	135619|Oceanospirillales	NU	Pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_2005158_37	1209989.TepiRe1_0766	2.559e-17	85.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,42GZ3@68295|Thermoanaerobacterales	186801|Clostridia	G	phosphocarrier	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS3_k127_2005158_34	1121434.AULY01000006_gene330	4.452e-20	96.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2MC5C@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS3_k127_2005158_42	338963.Pcar_1937	0.0003748	51.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,43TY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
CMS3_k127_2005158_14	880072.Desac_0139	2.44e-54	200.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2MQGR@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS3_k127_2005158_12	278957.ABEA03000157_gene638	1.745e-62	242.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia,3K788@414999|Opitutae	414999|Opitutae	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS3_k127_2005158_1	290397.Adeh_0787	3.477e-179	599.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2YU2M@29|Myxococcales	28221|Deltaproteobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
CMS3_k127_2005158_18	1009370.ALO_17776	7.343e-50	184.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4H45H@909932|Negativicutes	909932|Negativicutes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS3_k127_2005158_30	649747.HMPREF0083_05797	6.816e-27	117.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26Y4X@186822|Paenibacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS3_k127_2005158_6	756272.Plabr_4720	8.478e-78	283.0	COG2812@1|root,COG3170@1|root,COG2812@2|Bacteria,COG3170@2|Bacteria,2IX1M@203682|Planctomycetes	203682|Planctomycetes	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS3_k127_2005158_25	342113.DM82_1675	6.186e-37	145.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,1K3Y2@119060|Burkholderiaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
CMS3_k127_2005158_7	1254432.SCE1572_00430	5.016e-74	261.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2YYG6@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_2005158_0	1121468.AUBR01000017_gene2394	1.549e-283	933.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS3_k127_2005158_28	1268239.PALB_1460	2.722e-30	124.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,2Q24U@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS3_k127_2005158_3	247490.KSU1_C1236	6.215e-113	374.0	COG0202@1|root,COG0202@2|Bacteria,2IXPQ@203682|Planctomycetes	203682|Planctomycetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS3_k127_2005158_10	1089553.Tph_c25580	1.765e-68	239.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS3_k127_2005158_19	756272.Plabr_2080	3.747e-49	177.0	COG0100@1|root,COG0100@2|Bacteria,2IZCP@203682|Planctomycetes	203682|Planctomycetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS3_k127_2005158_21	886293.Sinac_0463	2.987e-40	155.0	COG0099@1|root,COG0099@2|Bacteria,2IZK8@203682|Planctomycetes	203682|Planctomycetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS3_k127_2005158_39	485915.Dret_2043	1.523e-12	69.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2MDXC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS3_k127_2005158_38	1313265.JNIE01000002_gene731	4.649e-17	83.0	COG0361@1|root,COG0361@2|Bacteria,2G48D@200783|Aquificae	200783|Aquificae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS3_k127_2005158_11	1123371.ATXH01000034_gene775	1.316e-67	236.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS3_k127_2005158_4	756272.Plabr_2075	1.632e-109	369.0	COG0201@1|root,COG0201@2|Bacteria,2IXN6@203682|Planctomycetes	203682|Planctomycetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS3_k127_2005158_23	240016.ABIZ01000001_gene4061	3.035e-38	156.0	COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia,2IUE6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS3_k127_2005158_16	1142394.PSMK_29010	4.79e-50	185.0	COG0098@1|root,COG0098@2|Bacteria,2IZ7J@203682|Planctomycetes	203682|Planctomycetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS3_k127_2005158_29	880526.KE386488_gene493	6.006e-30	123.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,22VD9@171550|Rikenellaceae	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS3_k127_2005158_13	1227261.HMPREF0043_00856	4.375e-59	210.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4D3X4@85005|Actinomycetales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS3_k127_2005158_22	756272.Plabr_2070	1.729e-39	150.0	COG0096@1|root,COG0096@2|Bacteria,2IZ8I@203682|Planctomycetes	203682|Planctomycetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS3_k127_2005158_31	644968.DFW101_3217	5.181e-24	102.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2MD30@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS3_k127_2005158_8	861360.AARI_23350	3.078e-73	251.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,1W7ZH@1268|Micrococcaceae	201174|Actinobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS3_k127_2005158_33	1219035.NT2_02_03090	3.161e-21	102.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2UC6Y@28211|Alphaproteobacteria,2K52R@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS3_k127_2005158_15	237368.SCABRO_03495	3.267e-52	186.0	COG0093@1|root,COG0093@2|Bacteria,2IZMA@203682|Planctomycetes	203682|Planctomycetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS3_k127_2005158_32	765914.ThisiDRAFT_1679	3.06e-23	104.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,1WZA0@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS3_k127_2005158_40	706433.HMPREF9430_00155	5.064e-06	59.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,3VRP2@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS3_k127_2005158_17	273068.TTE2285	5.987e-50	181.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,42G0F@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS3_k127_2005158_9	886293.Sinac_0479	1.472e-68	241.0	COG0092@1|root,COG0092@2|Bacteria,2IWWU@203682|Planctomycetes	203682|Planctomycetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS3_k127_2005158_36	1408226.T233_01660	6.275e-19	95.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,4B2M0@81852|Enterococcaceae	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS3_k127_2005158_26	314230.DSM3645_09382	9.481e-36	137.0	COG0185@1|root,COG0185@2|Bacteria,2J0BB@203682|Planctomycetes	203682|Planctomycetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS3_k127_2005158_5	667014.Thein_1466	1.912e-104	346.0	COG0090@1|root,COG0090@2|Bacteria,2GGSH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS3_k127_2005158_35	891968.Anamo_0476	4.391e-19	89.0	COG0089@1|root,COG0089@2|Bacteria,3TBBG@508458|Synergistetes	508458|Synergistetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS3_k127_2005158_20	247490.KSU1_C1209	3.235e-42	161.0	COG0088@1|root,COG0088@2|Bacteria,2IYU2@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS3_k127_2010466_11	765869.BDW_03245	3.793e-16	83.0	2EQTX@1|root,33IDK@2|Bacteria,1NJ7Q@1224|Proteobacteria,42XE5@68525|delta/epsilon subdivisions,2MTFJ@213481|Bdellovibrionales,2WTE3@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SirB
CMS3_k127_2010466_6	1121904.ARBP01000007_gene2934	1.187e-80	277.0	COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,47MB3@768503|Cytophagia	2|Bacteria	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS3_k127_2010466_0	886293.Sinac_2513	1.112e-267	850.0	COG0550@1|root,COG0550@2|Bacteria,2J2NP@203682|Planctomycetes	203682|Planctomycetes	L	C-terminal repeat of topoisomerase	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
CMS3_k127_2010466_9	232348.ADXL01000037_gene1422	1.475e-34	154.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1GYHE@1129|Synechococcus	1117|Cyanobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_2010466_4	583355.Caka_1736	3.07e-121	436.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_2010466_12	1158294.JOMI01000007_gene659	0.0005216	51.0	2CA0F@1|root,3420R@2|Bacteria,4P4FC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2010466_3	886293.Sinac_6941	3.36e-141	460.0	COG0613@1|root,COG0613@2|Bacteria,2IX3G@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2010466_2	314230.DSM3645_09952	1.961e-146	479.0	COG1506@1|root,COG1506@2|Bacteria,2J51R@203682|Planctomycetes	203682|Planctomycetes	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2010466_7	1089551.KE386572_gene1405	1.229e-72	271.0	COG0667@1|root,COG0667@2|Bacteria,1MWGQ@1224|Proteobacteria,2TUJ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldo keto reductase	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
CMS3_k127_2010466_10	1254432.SCE1572_09310	6.125e-21	108.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3,fn3
CMS3_k127_2010466_8	204669.Acid345_0003	7.05e-48	183.0	COG1940@1|root,COG1940@2|Bacteria,3Y6YN@57723|Acidobacteria,2JKMS@204432|Acidobacteriia	204432|Acidobacteriia	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_2010466_5	42565.FP66_05135	4.765e-98	357.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,1RPQV@1236|Gammaproteobacteria,1XMZ0@135619|Oceanospirillales	135619|Oceanospirillales	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
CMS3_k127_2010466_1	575540.Isop_1644	1.103e-191	623.0	COG0265@1|root,COG3266@1|root,COG4447@1|root,COG0265@2|Bacteria,COG3266@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4,3.4.21.107	ko:K01179,ko:K04771	ko00500,ko01100,ko01503,ko02020,map00500,map01100,map01503,map02020	M00728	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH5,GH9	-	PDZ_2,Sortilin-Vps10,Trypsin_2
CMS3_k127_2020140_0	313628.LNTAR_22110	2.086e-291	922.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_2020140_1	313628.LNTAR_22115	7.072e-259	804.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_2022106_7	760192.Halhy_3824	4.952e-97	348.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_2022106_13	552811.Dehly_0536	7.137e-47	178.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS3_k127_2022106_15	521674.Plim_2243	4.617e-41	164.0	COG1974@1|root,COG1974@2|Bacteria,2IZCV@203682|Planctomycetes	203682|Planctomycetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS3_k127_2022106_26	181119.XP_005531560.1	2.379e-14	76.0	KOG4605@1|root,KOG4605@2759|Eukaryota,3A8Z4@33154|Opisthokonta,3CNFC@33208|Metazoa,3E4E3@33213|Bilateria	33208|Metazoa	S	Iron-binding zinc finger CDGSH type	CISD3	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CMS3_k127_2022106_6	864702.OsccyDRAFT_2400	2.961e-106	366.0	COG3975@1|root,COG3975@2|Bacteria,1G0YP@1117|Cyanobacteria,1H7J1@1150|Oscillatoriales	1117|Cyanobacteria	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CMS3_k127_2022106_20	234267.Acid_4096	9.614e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,3Y3HD@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2022106_27	205922.Pfl01_1364	4.233e-05	56.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1YRT8@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	MucB/RseB C-terminal domain	rseB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
CMS3_k127_2022106_24	886293.Sinac_2330	4.771e-19	99.0	COG0526@1|root,COG0526@2|Bacteria,2J0JE@203682|Planctomycetes	203682|Planctomycetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_2022106_14	551275.KB899546_gene2378	2.866e-46	184.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,43X2P@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	tacA	GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
CMS3_k127_2022106_5	761193.Runsl_0557	2.258e-118	403.0	COG0823@1|root,COG1680@1|root,COG0823@2|Bacteria,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,47JBV@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_2022106_19	411467.BACCAP_02370	1.524e-31	131.0	COG0564@1|root,COG0564@2|Bacteria,1TSPG@1239|Firmicutes,24D6E@186801|Clostridia,268P6@186813|unclassified Clostridiales	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_2022106_17	1442599.JAAN01000046_gene2756	1.085e-37	158.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1X9ST@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS3_k127_2022106_25	391625.PPSIR1_32387	2.371e-15	82.0	COG1965@1|root,COG1965@2|Bacteria,1QAVK@1224|Proteobacteria,435BR@68525|delta/epsilon subdivisions,2WZP7@28221|Deltaproteobacteria,2Z2G9@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the frataxin family	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
CMS3_k127_2022106_8	1192034.CAP_0061	6.63e-92	338.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YYCD@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_2022106_29	1134912.AJTV01000047_gene3499	0.0009594	52.0	COG0457@1|root,COG1413@1|root,COG3303@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,COG3303@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,36ZR3@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_2022106_9	986075.CathTA2_0866	1.569e-85	293.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli	91061|Bacilli	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2022106_11	1192034.CAP_7036	7.919e-76	269.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2YURG@29|Myxococcales	28221|Deltaproteobacteria	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS3_k127_2022106_21	944480.ATUV01000001_gene864	1.122e-28	128.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42QGR@68525|delta/epsilon subdivisions,2WKUQ@28221|Deltaproteobacteria,2M72K@213113|Desulfurellales	28221|Deltaproteobacteria	S	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS3_k127_2022106_0	247490.KSU1_B0370	7.108e-287	903.0	COG0188@1|root,COG0188@2|Bacteria,2IY0U@203682|Planctomycetes	203682|Planctomycetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS3_k127_2022106_23	240302.BN982_00290	2.838e-22	113.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3NEVZ@45667|Halobacillus	91061|Bacilli	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS3_k127_2022106_16	388467.A19Y_3284	1.773e-40	171.0	28KEP@1|root,2ZA0W@2|Bacteria,1G2EV@1117|Cyanobacteria,1H8V1@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2022106_3	1232410.KI421415_gene3060	6.331e-182	588.0	COG0826@1|root,COG0826@2|Bacteria,1QMCE@1224|Proteobacteria,42PSK@68525|delta/epsilon subdivisions,2WKMU@28221|Deltaproteobacteria,43UGW@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
CMS3_k127_2022106_10	1185876.BN8_00865	2.897e-76	286.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,47X4G@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
CMS3_k127_2022106_12	1122222.AXWR01000016_gene2531	1.344e-63	248.0	COG3794@1|root,COG3794@2|Bacteria,1WM8A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
CMS3_k127_2022106_4	1123242.JH636434_gene4779	7.227e-146	478.0	COG1473@1|root,COG1473@2|Bacteria,2IY78@203682|Planctomycetes	203682|Planctomycetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_2022106_1	1238182.C882_1839	1.489e-271	844.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2TT46@28211|Alphaproteobacteria,2JPDP@204441|Rhodospirillales	204441|Rhodospirillales	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
CMS3_k127_2022106_22	1121007.AUML01000022_gene842	5.025e-26	117.0	COG3043@1|root,COG3043@2|Bacteria,4NG82@976|Bacteroidetes,1HZDY@117743|Flavobacteriia,2YHZ9@290174|Aquimarina	976|Bacteroidetes	C	Nitrate reductase cytochrome c-type subunit (NapB)	-	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	Cytochrome_C554,NapB
CMS3_k127_2022106_2	398767.Glov_1056	4.04e-239	754.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2WKKT@28221|Deltaproteobacteria,43VZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA NapA NarB subfamily	-	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
CMS3_k127_2023985_20	1307761.L21SP2_1683	0.0004188	49.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
CMS3_k127_2023985_2	237368.SCABRO_03967	7.577e-102	360.0	COG1132@1|root,COG1132@2|Bacteria,2IXKY@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_2023985_11	861299.J421_3264	3.36e-38	158.0	COG0245@1|root,COG0245@2|Bacteria,1ZTM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CMS3_k127_2023985_10	1121930.AQXG01000015_gene1878	1.98e-40	161.0	COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,1ISH4@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	1.1.1.405,2.7.7.40,2.7.7.60	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R01525,R02921,R05633	RC00002,RC00089	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
CMS3_k127_2023985_13	1515613.HQ37_05470	4.932e-27	119.0	COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,2FNM6@200643|Bacteroidia,22WG4@171551|Porphyromonadaceae	976|Bacteroidetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS3_k127_2023985_12	1121434.AULY01000012_gene2776	8.363e-36	149.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42PF7@68525|delta/epsilon subdivisions,2WJB5@28221|Deltaproteobacteria,2M9FM@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
CMS3_k127_2023985_16	1137268.AZXF01000012_gene3542	1.443e-09	67.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS3_k127_2023985_6	1303518.CCALI_00718	3.213e-65	233.0	COG0157@1|root,COG0157@2|Bacteria	2|Bacteria	H	quinolinate catabolic process	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988,iHN637.CLJU_RS12010,iLJ478.TM1645	QRPTase_C,QRPTase_N
CMS3_k127_2023985_19	1415166.NONO_c20060	7.829e-05	52.0	COG2172@1|root,COG2172@2|Bacteria,2GURF@201174|Actinobacteria,4G2X1@85025|Nocardiaceae	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
CMS3_k127_2023985_18	649638.Trad_1763	5.758e-08	61.0	COG5652@1|root,COG5652@2|Bacteria,1WK8S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM VanZ like	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS3_k127_2023985_1	4787.PITG_17983T0	2.65e-163	527.0	COG0015@1|root,KOG2700@2759|Eukaryota,3Q8UB@4776|Peronosporales	4776|Peronosporales	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS3_k127_2023985_4	251221.35214774	1.01e-82	307.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
CMS3_k127_2023985_17	1274.HX89_10965	1.721e-08	65.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,1ZWSX@145357|Dermacoccaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2023985_0	335543.Sfum_0263	0.0	1230.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MQ8A@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_2023985_8	1316936.K678_05763	4.189e-52	196.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria,2JSNX@204441|Rhodospirillales	204441|Rhodospirillales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_2023985_3	1238182.C882_1718	3.112e-86	301.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,2U4VF@28211|Alphaproteobacteria,2JRM3@204441|Rhodospirillales	204441|Rhodospirillales	G	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
CMS3_k127_2023985_9	391625.PPSIR1_11120	8.883e-47	172.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2YVDP@29|Myxococcales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS3_k127_2023985_7	443144.GM21_1931	5.461e-64	233.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria,43SCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
CMS3_k127_2023985_15	1123405.AUMM01000002_gene398	5.109e-17	89.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,26NRJ@186821|Sporolactobacillaceae	91061|Bacilli	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS3_k127_2023985_5	338963.Pcar_2210	6.886e-71	252.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,43SBK@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	MraW methylase family	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS3_k127_2024955_0	1123242.JH636435_gene2890	1.79e-11	78.0	COG2304@1|root,COG2304@2|Bacteria,2J43F@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_3
CMS3_k127_2027025_3	1210884.HG799466_gene13033	1.179e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,2J3UV@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CMS3_k127_2027025_1	685778.AORL01000021_gene782	4.241e-79	280.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria,2K0WY@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_2027025_2	84531.JMTZ01000022_gene4190	4.861e-14	81.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,1SCVJ@1236|Gammaproteobacteria,1X7BK@135614|Xanthomonadales	135614|Xanthomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS3_k127_2027025_0	240016.ABIZ01000001_gene1248	1.191e-128	438.0	COG4206@1|root,COG4206@2|Bacteria,46Z2R@74201|Verrucomicrobia,2IU2X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS3_k127_2032077_1	1220534.B655_0403	1.542e-66	254.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,23PEV@183925|Methanobacteria	183925|Methanobacteria	L	PFAM Endonuclease Exonuclease phosphatase	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS3_k127_2032077_0	344747.PM8797T_07337	1.479e-136	452.0	COG0591@1|root,COG0591@2|Bacteria,2IXNM@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS3_k127_2033806_0	497964.CfE428DRAFT_0194	0.0	1276.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
CMS3_k127_2033806_4	926550.CLDAP_34490	2.919e-96	322.0	COG1210@1|root,COG1210@2|Bacteria,2G6XV@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_2033806_14	1120965.AUBV01000019_gene1142	1.19e-08	68.0	COG1572@1|root,COG3209@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,4PNJW@976|Bacteroidetes	976|Bacteroidetes	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,DUF4465
CMS3_k127_2033806_3	1123242.JH636435_gene1579	1.004e-104	359.0	28JEC@1|root,2Z98J@2|Bacteria,2IX0J@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2033806_13	1210884.HG799462_gene8840	1.834e-10	72.0	2B9NZ@1|root,30TS7@2|Bacteria,2J1HS@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS3_k127_2033806_15	1380355.JNIJ01000041_gene5224	3.617e-07	58.0	COG2801@1|root,COG2801@2|Bacteria,1MX69@1224|Proteobacteria,2TSIE@28211|Alphaproteobacteria,3K2DN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
CMS3_k127_2033806_5	886293.Sinac_6489	2.244e-81	306.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_2033806_16	866536.Belba_1804	2.568e-06	59.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,47KED@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_2033806_1	314230.DSM3645_04530	5.742e-253	817.0	COG1020@1|root,COG1020@2|Bacteria,2IXA9@203682|Planctomycetes	203682|Planctomycetes	Q	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_2033806_2	314230.DSM3645_04535	7.069e-165	532.0	COG2960@1|root,COG2960@2|Bacteria,2IYQY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_2033806_8	596153.Alide_0314	2.707e-58	210.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,2VM6W@28216|Betaproteobacteria,4AAMQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator	ompR2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2033806_9	316274.Haur_2307	1.198e-37	161.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_2033806_7	13035.Dacsa_2035	6.897e-60	215.0	COG2905@1|root,COG2905@2|Bacteria,1GPZ1@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
CMS3_k127_2033806_6	448385.sce5671	1.284e-64	231.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_2033806_10	1497679.EP56_17670	2.691e-23	111.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli,26KFZ@186820|Listeriaceae	91061|Bacilli	E	Lactoylglutathione lyase	gloA	-	4.4.1.5	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	M00491	R02530	RC00004,RC00740	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	Glyoxalase
CMS3_k127_2033806_11	234267.Acid_2830	2.881e-20	99.0	COG2230@1|root,COG2230@2|Bacteria,3Y9AA@57723|Acidobacteria	57723|Acidobacteria	M	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_2042368_33	595460.RRSWK_04400	5.444e-06	58.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07716,ko:K13924	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg,dCache_1
CMS3_k127_2042368_34	861299.J421_6360	5.078e-05	56.0	2F0M3@1|root,33TPR@2|Bacteria,1ZUAZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2042368_8	1131269.AQVV01000013_gene1726	1.54e-108	372.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_2042368_11	313628.LNTAR_07834	1.548e-80	282.0	COG1137@1|root,COG1137@2|Bacteria	2|Bacteria	S	lipopolysaccharide-transporting ATPase activity	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS3_k127_2042368_28	756272.Plabr_1329	6.547e-22	111.0	COG0681@1|root,COG0681@2|Bacteria,2IY6X@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS3_k127_2042368_1	1235799.C818_04147	1.663e-224	714.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,27JHP@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS3_k127_2042368_20	663278.Ethha_0322	6.709e-45	179.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS3_k127_2042368_12	596329.HMPREF0631_0113	4.43e-75	259.0	COG0127@1|root,COG0689@1|root,COG0127@2|Bacteria,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,25QCQ@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
CMS3_k127_2042368_35	765911.Thivi_1437	0.0003154	53.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1SKIP@1236|Gammaproteobacteria,1X03X@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_2042368_37	1400520.LFAB_16200	0.0008692	52.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HBC7@91061|Bacilli,3F4XS@33958|Lactobacillaceae	91061|Bacilli	G	Glycosyl hydrolases family 38 N-terminal domain	mngB	-	3.2.1.170	ko:K15524	-	-	-	-	ko00000,ko01000	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS3_k127_2042368_15	251221.35214543	8.724e-56	203.0	COG0500@1|root,COG2226@2|Bacteria,1G0W5@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_2042368_32	240292.Ava_3187	3.165e-06	58.0	COG0664@1|root,COG0664@2|Bacteria,1G3SU@1117|Cyanobacteria,1HRGH@1161|Nostocales	1117|Cyanobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_2042368_22	1123253.AUBD01000002_gene1389	3.952e-31	141.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,1X33H@135614|Xanthomonadales	135614|Xanthomonadales	N	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
CMS3_k127_2042368_25	1120972.AUMH01000011_gene209	5.932e-25	120.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,4HAAY@91061|Bacilli,277ZW@186823|Alicyclobacillaceae	91061|Bacilli	N	flagellar motor switch protein FliM	fliM	GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
CMS3_k127_2042368_29	457570.Nther_1406	5.013e-18	98.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flin	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
CMS3_k127_2042368_27	1120963.KB894504_gene1859	8.319e-23	106.0	2E3EZ@1|root,32YDW@2|Bacteria,1NFAN@1224|Proteobacteria,1SFXI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2042368_36	398580.Dshi_1814	0.0004395	53.0	COG2931@1|root,COG2931@2|Bacteria,1NV5X@1224|Proteobacteria,2URVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2042368_19	411464.DESPIG_01931	6.921e-48	184.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria,2M84A@213115|Desulfovibrionales	28221|Deltaproteobacteria	KQ	PFAM Methyltransferase type 11	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
CMS3_k127_2042368_0	1254432.SCE1572_34940	0.0	1706.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS3_k127_2042368_10	398767.Glov_3245	1.04e-90	322.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,43S1P@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
CMS3_k127_2042368_16	1122221.JHVI01000010_gene2506	6.652e-55	211.0	COG0745@1|root,COG0745@2|Bacteria	1122221.JHVI01000010_gene2506|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2042368_21	1300345.LF41_1565	2.659e-34	144.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RQ3H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_2042368_6	1121035.AUCH01000003_gene1371	2.619e-126	434.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,2KUUJ@206389|Rhodocyclales	206389|Rhodocyclales	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_2042368_9	929556.Solca_2810	1.523e-98	347.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS3_k127_2042368_17	926550.CLDAP_19100	1.243e-54	218.0	COG0181@1|root,COG0181@2|Bacteria,2G6JU@200795|Chloroflexi	200795|Chloroflexi	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS3_k127_2042368_24	1089549.AZUQ01000001_gene705	1.326e-26	124.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4EY2K@85014|Glycomycetales	201174|Actinobacteria	H	Glutamyl-tRNAGlu reductase, N-terminal domain	hemA	GO:0008150,GO:0040007	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_2042368_18	1382359.JIAL01000001_gene2001	1.786e-50	208.0	28JDZ@1|root,2Z988@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2042368_2	448385.sce3157	6.814e-219	696.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	GATase,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS3_k127_2042368_26	1469613.JT55_09030	1.356e-24	119.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
CMS3_k127_2042368_13	357808.RoseRS_0056	1.85e-62	237.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,2GB6S@200795|Chloroflexi,377GI@32061|Chloroflexia	32061|Chloroflexia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
CMS3_k127_2042368_5	1125863.JAFN01000001_gene929	3e-179	583.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS3_k127_2042368_38	378806.STAUR_7145	0.0009136	53.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1Q2N1@1224|Proteobacteria,4388U@68525|delta/epsilon subdivisions,2X3IG@28221|Deltaproteobacteria,2Z0RK@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2042368_7	756272.Plabr_1722	3.324e-119	421.0	COG4927@1|root,COG4927@2|Bacteria	2|Bacteria	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_2042368_14	314230.DSM3645_20287	2.52e-58	232.0	COG1073@1|root,COG1073@2|Bacteria,2IZ53@203682|Planctomycetes	203682|Planctomycetes	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2048,Peptidase_S9
CMS3_k127_2042368_4	316067.Geob_1167	1.41e-185	592.0	COG0057@1|root,COG0057@2|Bacteria,1MZE4@1224|Proteobacteria,42QIB@68525|delta/epsilon subdivisions,2WKXI@28221|Deltaproteobacteria,43SDB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapB	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_2042368_3	344747.PM8797T_18876	2.443e-189	605.0	COG3119@1|root,COG3119@2|Bacteria,2J2DZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS3_k127_2042368_30	243231.GSU2508	7.09e-18	98.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_2042368_23	1161401.ASJA01000009_gene1843	5.969e-27	124.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,2TQME@28211|Alphaproteobacteria,43XB5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS3_k127_2042368_31	1120956.JHZK01000001_gene3421	5.918e-09	61.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TU5D@28211|Alphaproteobacteria,1JQMI@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
CMS3_k127_2044194_0	756272.Plabr_0079	2.283e-235	757.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_2044194_2	1122194.AUHU01000004_gene1451	6.54e-100	331.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,465VZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2044194_1	1173024.KI912148_gene3732	5.394e-197	643.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_2044194_3	595460.RRSWK_03455	1.258e-79	280.0	COG0845@1|root,COG0845@2|Bacteria,2J07G@203682|Planctomycetes	203682|Planctomycetes	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS3_k127_2044194_7	1487921.DP68_09300	0.0004366	53.0	COG3063@1|root,COG3063@2|Bacteria,1UFME@1239|Firmicutes,24HJ1@186801|Clostridia,36J13@31979|Clostridiaceae	186801|Clostridia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2044194_4	530564.Psta_2910	1.459e-31	143.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_2044194_6	1121403.AUCV01000035_gene3820	1.196e-07	57.0	COG1393@1|root,COG1393@2|Bacteria,1NNVX@1224|Proteobacteria,42XJB@68525|delta/epsilon subdivisions,2WT31@28221|Deltaproteobacteria,2MMB9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2044194_5	1463887.KL589999_gene5690	2.719e-19	99.0	COG0662@1|root,COG0662@2|Bacteria,2IHNU@201174|Actinobacteria	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_2053135_16	886293.Sinac_6278	3.694e-12	79.0	COG4219@1|root,COG4219@2|Bacteria,2J205@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Thioredoxin_7
CMS3_k127_2053135_6	886293.Sinac_1073	1.713e-70	269.0	COG0647@1|root,COG0647@2|Bacteria	2|Bacteria	G	UMP catabolic process	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_2053135_0	344747.PM8797T_27864	7.627e-123	420.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2053135_7	13035.Dacsa_1064	6.617e-70	261.0	COG0616@1|root,COG0616@2|Bacteria,1G1AY@1117|Cyanobacteria	1117|Cyanobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_2053135_8	671143.DAMO_0253	1.665e-62	227.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
CMS3_k127_2053135_15	756272.Plabr_2435	1.36e-16	94.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159,Prenyltrans
CMS3_k127_2053135_10	575540.Isop_1883	1.362e-52	208.0	COG2234@1|root,COG2234@2|Bacteria,2J3AQ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_2053135_2	502025.Hoch_5472	1.364e-100	345.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YYM7@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpX chaperone family	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS3_k127_2053135_11	1136417.AZWE01000042_gene157	1.799e-44	164.0	COG0537@1|root,COG0537@2|Bacteria,2IT1Z@201174|Actinobacteria,4DJJE@85008|Micromonosporales	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_2053135_3	1232452.BAIB02000018_gene2629	2.046e-80	293.0	COG2334@1|root,COG2334@2|Bacteria,1VRV5@1239|Firmicutes,25EGP@186801|Clostridia,268AG@186813|unclassified Clostridiales	186801|Clostridia	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_2053135_9	382464.ABSI01000010_gene3418	2.193e-60	230.0	COG0225@1|root,COG0225@2|Bacteria,46SSF@74201|Verrucomicrobia,2IU9E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS3_k127_2053135_13	671143.DAMO_2125	6.114e-23	105.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_2053135_1	530564.Psta_4579	2.512e-122	406.0	COG0673@1|root,COG0673@2|Bacteria,2IXDR@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_2053135_12	1232410.KI421413_gene804	1.984e-30	121.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,43SPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Translation initiation factor 1A / IF-1	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS3_k127_2053135_14	595460.RRSWK_03230	3.75e-20	93.0	2E71C@1|root,331K1@2|Bacteria,2J130@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2053135_4	1150474.JQJI01000014_gene701	1.836e-78	288.0	COG0557@1|root,COG0557@2|Bacteria,2GC0U@200918|Thermotogae	200918|Thermotogae	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
CMS3_k127_2053135_5	1144275.COCOR_06708	4.091e-73	258.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,42SUN@68525|delta/epsilon subdivisions,2WPCU@28221|Deltaproteobacteria,2YXKB@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_2053135_17	1229520.ADIAL_0076	1.17e-05	50.0	COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,27FY1@186828|Carnobacteriaceae	91061|Bacilli	S	ABC transporter	-	-	-	ko:K18231,ko:K19349	ko02010,map02010	-	-	-	br01600,ko00000,ko00001,ko01504,ko02000	3.A.1.121.1,3.A.1.121.2,3.A.1.121.3	-	-	ABC_tran,ABC_tran_Xtn
CMS3_k127_2053773_20	452637.Oter_4337	2.667e-64	227.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
CMS3_k127_2053773_9	234267.Acid_2671	1.778e-110	384.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,3Y7VX@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS3_k127_2053773_37	452637.Oter_4340	4.471e-10	70.0	COG1410@1|root,COG1410@2|Bacteria,46UVC@74201|Verrucomicrobia	74201|Verrucomicrobia	E	methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2053773_12	452637.Oter_4332	3.947e-90	316.0	COG0646@1|root,COG0646@2|Bacteria,46SYT@74201|Verrucomicrobia,3K9JH@414999|Opitutae	414999|Opitutae	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS3_k127_2053773_13	697281.Mahau_2725	5.879e-90	309.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,42IQ4@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS3_k127_2053773_34	502025.Hoch_2959	1.634e-19	105.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
CMS3_k127_2053773_0	1045855.DSC_02940	1.619e-231	742.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,1RMSV@1236|Gammaproteobacteria,1X31I@135614|Xanthomonadales	135614|Xanthomonadales	E	peptidase	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_2053773_25	1122939.ATUD01000001_gene577	1.172e-41	175.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2053773_38	1306406.ASHX01000001_gene910	3.794e-09	65.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2053773_22	1123508.JH636449_gene7349	2.264e-61	240.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2053773_5	1219084.AP014508_gene1090	7.452e-141	462.0	COG0205@1|root,COG0205@2|Bacteria,2GC8H@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS3_k127_2053773_31	1229781.C272_11108	9.918e-28	123.0	COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4F9J8@85019|Brevibacteriaceae	201174|Actinobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_2053773_28	1298880.AUEV01000007_gene4573	7.852e-39	150.0	COG0346@1|root,COG0346@2|Bacteria,2IQE0@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_2053773_18	1227487.C474_03200	6.738e-74	276.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_2053773_1	452637.Oter_0062	3.653e-222	709.0	COG4993@1|root,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
CMS3_k127_2053773_21	243090.RB9222	1.043e-61	226.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,2IXR8@203682|Planctomycetes	203682|Planctomycetes	MO	MucD-putative a secreted serine proteinase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
CMS3_k127_2053773_14	344747.PM8797T_20793	1.143e-88	319.0	28ND0@1|root,2ZBFU@2|Bacteria,2J2X6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2053773_30	945713.IALB_0149	1.605e-31	130.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
CMS3_k127_2053773_4	1121859.KB890739_gene2823	1.794e-148	485.0	COG1062@1|root,COG1062@2|Bacteria,4NF83@976|Bacteroidetes,47NW9@768503|Cytophagia	976|Bacteroidetes	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_2053773_11	1123508.JH636439_gene665	8.336e-91	312.0	COG3345@1|root,COG3345@2|Bacteria,2IZER@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_2053773_26	204669.Acid345_3127	3.091e-41	163.0	COG0500@1|root,COG2226@2|Bacteria,3Y8WR@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2053773_17	926562.Oweho_1142	1.37e-80	283.0	COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,1HXT9@117743|Flavobacteriia,2PAAR@246874|Cryomorphaceae	976|Bacteroidetes	E	PFAM Peptidase C1-like family	-	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
CMS3_k127_2053773_7	99598.Cal7507_1012	5.194e-123	404.0	COG0057@1|root,COG0057@2|Bacteria,1G0ZV@1117|Cyanobacteria,1HKGS@1161|Nostocales	1117|Cyanobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap3	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_2053773_36	1278073.MYSTI_04884	7.207e-15	90.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2053773_39	67373.JOBF01000005_gene1994	2.072e-08	68.0	COG1595@1|root,COG1595@2|Bacteria,2IHGE@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2053773_10	1379698.RBG1_1C00001G0998	7.701e-108	362.0	COG0825@1|root,COG0825@2|Bacteria,2NNVQ@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accA	ACCA
CMS3_k127_2053773_29	717605.Theco_0340	2.575e-32	135.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2053773_40	314230.DSM3645_03568	0.0003851	53.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PDZ_2,Peptidase_M28
CMS3_k127_2053773_15	1382356.JQMP01000003_gene1710	3.116e-87	301.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,27XRH@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS3_k127_2053773_3	1121090.KB894701_gene3362	4.589e-150	486.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS3_k127_2053773_16	247490.KSU1_D0480	4.458e-82	277.0	COG0740@1|root,COG0740@2|Bacteria,2IXQN@203682|Planctomycetes	203682|Planctomycetes	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS3_k127_2053773_23	457570.Nther_1101	9.589e-52	201.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS3_k127_2053773_2	1111479.AXAR01000002_gene2023	1.379e-161	530.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,277VE@186823|Alicyclobacillaceae	91061|Bacilli	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS3_k127_2053773_35	1160718.SU9_14721	7.365e-16	92.0	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_2053773_33	1267533.KB906741_gene652	2.502e-24	106.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	ysfE	-	2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5	ko:K00941,ko:K01724,ko:K01759,ko:K07032,ko:K08234	ko00620,ko00730,ko00790,ko01100,map00620,map00730,map00790,map01100	M00127	R02530,R03471,R04509,R04734	RC00002,RC00004,RC00017,RC00740,RC01208	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
CMS3_k127_2053773_27	1123501.KB902312_gene2784	4.47e-41	157.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,2TWST@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_2053773_8	391625.PPSIR1_04458	1.751e-116	383.0	COG0171@1|root,COG0171@2|Bacteria	2|Bacteria	H	NAD+ synthase (glutamine-hydrolyzing) activity	nadE	GO:0000003,GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019954,GO:0030436,GO:0032502,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_1910,iECW_1372.ECW_m1909,iEKO11_1354.EKO11_2035,iETEC_1333.ETEC_1772,iEcE24377_1341.EcE24377A_1961,iSFV_1184.SFV_1480,iSF_1195.SF1486,iSFxv_1172.SFxv_1676,iSSON_1240.SSON_1418,iS_1188.S1603,iWFL_1372.ECW_m1909	NAD_synthase
CMS3_k127_2053773_32	477974.Daud_1363	1.607e-27	119.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,26290@186807|Peptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS3_k127_2053773_19	344747.PM8797T_22163	2.166e-66	256.0	COG0202@1|root,COG0457@1|root,COG0202@2|Bacteria,COG0457@2|Bacteria,2IXMK@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase alpha	-	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,TPR_1,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
CMS3_k127_2053773_24	326427.Cagg_0797	1.412e-46	184.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2G7Z3@200795|Chloroflexi,376IC@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2053773_6	583355.Caka_1954	8.305e-125	414.0	COG0766@1|root,COG0766@2|Bacteria,46U7P@74201|Verrucomicrobia,3K78X@414999|Opitutae	414999|Opitutae	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS3_k127_2060134_5	35754.JNYJ01000057_gene8669	1.93e-60	220.0	COG1352@1|root,COG1352@2|Bacteria,2HHZ1@201174|Actinobacteria,4D9IJ@85008|Micromonosporales	201174|Actinobacteria	NT	Methyltransferase, chemotaxis proteins	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS3_k127_2060134_9	1869.MB27_39495	1.93e-07	63.0	2E77D@1|root,331R6@2|Bacteria,2I2XP@201174|Actinobacteria,4DF3H@85008|Micromonosporales	201174|Actinobacteria	S	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
CMS3_k127_2060134_4	1033730.CAHG01000008_gene3165	1.091e-64	233.0	COG0840@1|root,COG0840@2|Bacteria,2HVFN@201174|Actinobacteria,4DT2P@85009|Propionibacteriales	201174|Actinobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signalling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
CMS3_k127_2060134_1	1089455.MOPEL_020_00010	2.188e-146	504.0	COG0643@1|root,COG0643@2|Bacteria,2IBKY@201174|Actinobacteria,4F62B@85018|Dermatophilaceae	201174|Actinobacteria	NT	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CMS3_k127_2060134_8	373903.Hore_22600	1.158e-18	101.0	COG0835@1|root,COG0835@2|Bacteria,1V77N@1239|Firmicutes,24M5B@186801|Clostridia,3WBQC@53433|Halanaerobiales	186801|Clostridia	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CMS3_k127_2060134_0	350688.Clos_2257	6.823e-300	989.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_2060134_7	357808.RoseRS_0981	2.314e-33	136.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS3_k127_2060134_6	1121957.ATVL01000006_gene2744	6.377e-35	154.0	COG2272@1|root,COG2272@2|Bacteria,4PMEB@976|Bacteroidetes,47Y2U@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
CMS3_k127_2060134_3	1121447.JONL01000011_gene2321	1.713e-93	332.0	COG1196@1|root,COG1196@2|Bacteria,1MVMQ@1224|Proteobacteria,42NF4@68525|delta/epsilon subdivisions,2WIMP@28221|Deltaproteobacteria,2M9K9@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2060134_2	861299.J421_0659	1.775e-96	358.0	COG0154@1|root,COG0154@2|Bacteria,1ZT2R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CMS3_k127_2064058_4	1202768.JROF01000005_gene2365	3.806e-20	100.0	COG0382@1|root,arCOG00476@2157|Archaea,2XVWN@28890|Euryarchaeota,23UXI@183963|Halobacteria	183963|Halobacteria	H	COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_2064058_2	237368.SCABRO_01801	3.112e-82	297.0	COG0750@1|root,COG0750@2|Bacteria,2IXWE@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CMS3_k127_2064058_1	667014.Thein_2089	6.182e-102	347.0	COG0743@1|root,COG0743@2|Bacteria,2GHA5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS3_k127_2064058_3	926550.CLDAP_00400	3.04e-25	120.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_2064058_0	1121377.KB906398_gene2403	4.979e-103	347.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_2064399_1	1304872.JAGC01000003_gene3036	2.017e-15	88.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_2064399_0	886293.Sinac_2761	3.092e-18	98.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_2096216_3	671143.DAMO_0070	9.505e-66	237.0	COG4974@1|root,COG4974@2|Bacteria,2NP4H@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase, N-terminal SAM-like domain	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_2096216_0	313628.LNTAR_02864	0.0	1029.0	COG3696@1|root,COG3696@2|Bacteria	2|Bacteria	P	silver ion transport	czcA	-	-	ko:K07239,ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1,2.A.6.1.4	-	-	ACR_tran
CMS3_k127_2096216_2	313628.LNTAR_02859	2.437e-69	269.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
CMS3_k127_2096216_12	1038869.AXAN01000001_gene3800	1.489e-09	70.0	COG1538@1|root,COG1538@2|Bacteria,1RFMJ@1224|Proteobacteria,2W2GG@28216|Betaproteobacteria,1K5MV@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
CMS3_k127_2096216_4	1396141.BATP01000039_gene1434	6.447e-51	188.0	COG1051@1|root,COG1051@2|Bacteria,46VWV@74201|Verrucomicrobia,2IVYW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_2096216_7	237368.SCABRO_00204	4.483e-33	140.0	COG1386@1|root,COG1386@2|Bacteria,2IZNB@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS3_k127_2096216_15	665959.HMPREF1013_04281	0.0009099	51.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4IQKZ@91061|Bacilli,1ZRKZ@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
CMS3_k127_2096216_14	1123508.JH636449_gene7253	0.0003887	53.0	COG2165@1|root,COG2165@2|Bacteria,2J08S@203682|Planctomycetes	203682|Planctomycetes	NU	prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS3_k127_2096216_13	1244869.H261_15947	1.494e-05	59.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,2JRWZ@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_16
CMS3_k127_2096216_10	237368.SCABRO_00273	1.456e-16	93.0	COG4972@1|root,COG4972@2|Bacteria,2IZC6@203682|Planctomycetes	203682|Planctomycetes	NU	pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_2096216_11	105422.BBPM01000011_gene7179	4.578e-13	83.0	COG0654@1|root,COG1716@1|root,COG0654@2|Bacteria,COG1716@2|Bacteria,2I9P3@201174|Actinobacteria,2NKMN@228398|Streptacidiphilus	201174|Actinobacteria	CHT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_2096216_8	614083.AWQR01000025_gene3747	1.674e-28	124.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,4ABUM@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS3_k127_2096216_5	1121468.AUBR01000001_gene497	1.667e-49	185.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS3_k127_2096216_9	237368.SCABRO_01095	3.777e-19	101.0	COG0457@1|root,COG0457@2|Bacteria	237368.SCABRO_01095|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2096216_6	756272.Plabr_4386	1.336e-43	183.0	COG0515@1|root,COG0515@2|Bacteria,2IZ0Z@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2096216_1	697281.Mahau_0438	3.473e-81	286.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS3_k127_210601_0	908339.HMPREF9265_1630	1.616e-69	256.0	COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae	91061|Bacilli	L	Helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
CMS3_k127_2108422_13	1206725.BAFU01000049_gene1305	0.0003526	52.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4FUVY@85025|Nocardiaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_2108422_8	330214.NIDE3221	4.726e-25	121.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2108422_11	448385.sce8268	3.616e-06	59.0	COG0784@1|root,COG0784@2|Bacteria,1QAM7@1224|Proteobacteria,43563@68525|delta/epsilon subdivisions,2WZH3@28221|Deltaproteobacteria,2Z24X@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
CMS3_k127_2108422_0	1480694.DC28_11295	3.976e-131	431.0	COG1816@1|root,COG1816@2|Bacteria	2|Bacteria	F	deaminase activity	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
CMS3_k127_2108422_5	1282362.AEAC466_05095	9.164e-43	172.0	COG1649@1|root,COG1649@2|Bacteria,1R6SN@1224|Proteobacteria,2U2S1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2108422_12	1122929.KB908215_gene802	0.0001018	56.0	COG5126@1|root,COG5126@2|Bacteria	2|Bacteria	DTZ	Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_2108422_10	439235.Dalk_1645	7.955e-18	100.0	COG5276@1|root,COG5276@2|Bacteria,1PE5R@1224|Proteobacteria,4375P@68525|delta/epsilon subdivisions,2X232@28221|Deltaproteobacteria,2MM6B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS3_k127_2108422_2	425104.Ssed_4024	4.007e-71	276.0	COG3303@1|root,COG3303@2|Bacteria,1QXPE@1224|Proteobacteria,1T4FP@1236|Gammaproteobacteria,2QC9C@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_2108422_9	639030.JHVA01000001_gene593	7.824e-25	119.0	COG3119@1|root,COG3119@2|Bacteria,3Y2QE@57723|Acidobacteria,2JKHV@204432|Acidobacteriia	204432|Acidobacteriia	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2108422_7	344747.PM8797T_11294	1.782e-35	158.0	COG1183@1|root,COG1183@2|Bacteria,2IZHR@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_2108422_3	1121430.JMLG01000002_gene1142	2.666e-69	262.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,26011@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS3_k127_2108422_6	1121918.ARWE01000001_gene933	2.235e-38	165.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_2108422_4	247490.KSU1_D1034	1.207e-46	179.0	COG2088@1|root,COG2088@2|Bacteria,2IZR8@203682|Planctomycetes	203682|Planctomycetes	D	Belongs to the SpoVG family	-	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
CMS3_k127_2108422_1	1122182.KB903833_gene5429	2.471e-111	391.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2I9U6@201174|Actinobacteria,4DH83@85008|Micromonosporales	201174|Actinobacteria	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
CMS3_k127_2110269_3	1380356.JNIK01000013_gene4194	1.534e-14	89.0	COG0515@1|root,COG0515@2|Bacteria,2I6W6@201174|Actinobacteria,4EXHA@85013|Frankiales	1380356.JNIK01000013_gene4194|-	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2110269_0	1003200.AXXA_06148	1.926e-69	259.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2110269_1	41431.PCC8801_4432	5.162e-56	207.0	COG0639@1|root,COG0639@2|Bacteria,1GQ67@1117|Cyanobacteria,3KGKG@43988|Cyanothece	1117|Cyanobacteria	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
CMS3_k127_2110269_2	1157638.KB892161_gene3059	2.292e-22	104.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS3_k127_2115018_0	290397.Adeh_2510	1.793e-129	425.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2Z349@29|Myxococcales	28221|Deltaproteobacteria	G	DeoC/LacD family aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
CMS3_k127_2115018_1	583355.Caka_2412	1.196e-26	113.0	COG2363@1|root,COG2363@2|Bacteria,46T86@74201|Verrucomicrobia,3K8CR@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS3_k127_2117441_20	530564.Psta_4488	6.029e-36	140.0	COG2755@1|root,COG2755@2|Bacteria,2J0Y1@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_2117441_0	1380394.JADL01000024_gene101	1.14e-275	887.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JRCI@204441|Rhodospirillales	204441|Rhodospirillales	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
CMS3_k127_2117441_4	326427.Cagg_2469	1.116e-154	503.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_2117441_13	204669.Acid345_3014	3.887e-73	274.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_2117441_7	497964.CfE428DRAFT_5722	4.031e-92	329.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
CMS3_k127_2117441_6	237368.SCABRO_00125	1.585e-92	310.0	COG1131@1|root,COG1131@2|Bacteria,2IXQV@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_2117441_15	1523503.JPMY01000002_gene3821	1.706e-59	214.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS3_k127_2117441_10	237368.SCABRO_00123	2.285e-87	314.0	COG3225@1|root,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
CMS3_k127_2117441_25	882378.RBRH_01614	6.103e-17	96.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1K2ZM@119060|Burkholderiaceae	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS3_k127_2117441_12	404589.Anae109_0565	5.328e-79	278.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_2117441_8	1123242.JH636434_gene3868	6.19e-91	321.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2117441_19	886293.Sinac_0140	6.365e-42	167.0	2EGZK@1|root,33ARQ@2|Bacteria,2J4A7@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2117441_5	1519464.HY22_09345	1.94e-126	419.0	COG1236@1|root,COG1236@2|Bacteria,1FER3@1090|Chlorobi	1090|Chlorobi	J	PFAM beta-lactamase domain protein	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CMS3_k127_2117441_21	1336208.JADY01000004_gene3542	1e-33	150.0	COG2246@1|root,COG2246@2|Bacteria,1QUSS@1224|Proteobacteria,2TW63@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2117441_1	869210.Marky_0660	8.634e-198	627.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS3_k127_2117441_23	1397527.Q670_06220	1.953e-27	132.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1XHNX@135619|Oceanospirillales	135619|Oceanospirillales	M	penicillin-binding protein	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CMS3_k127_2117441_29	869213.JCM21142_104122	0.0002956	55.0	COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,47KYC@768503|Cytophagia	976|Bacteroidetes	M	penicillin-binding protein 1C	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CMS3_k127_2117441_3	1089550.ATTH01000001_gene237	9.357e-158	526.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS3_k127_2117441_17	391587.KAOT1_08849	5.389e-48	186.0	29ZGM@1|root,30MGC@2|Bacteria,4NNY9@976|Bacteroidetes,1I2DF@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2117441_28	1476876.JOJO01000013_gene4589	1.447e-06	61.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,PA14
CMS3_k127_2117441_2	575540.Isop_3370	2.979e-166	545.0	COG3386@1|root,COG3386@2|Bacteria,2J2MK@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS3_k127_2117441_14	530564.Psta_3458	1.107e-62	226.0	COG1416@1|root,COG4798@1|root,COG1416@2|Bacteria,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
CMS3_k127_2117441_27	9823.ENSSSCP00000012206	7.968e-09	69.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,48YJP@7742|Vertebrata,3JF6U@40674|Mammalia,4J4DX@91561|Cetartiodactyla	33208|Metazoa	T	Inter-alpha-trypsin inhibitor heavy chain	ITIH4	GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA
CMS3_k127_2117441_24	59196.RICGR_0068	2.766e-19	100.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SC7S@1236|Gammaproteobacteria,1JEZ1@118969|Legionellales	118969|Legionellales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS3_k127_2117441_26	234267.Acid_3783	7.014e-10	72.0	COG5010@1|root,COG5010@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K13486	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Acetyltransf_6,DUF1570,Response_reg,TPR_16,TPR_19
CMS3_k127_2117441_16	290397.Adeh_0078	2.678e-50	196.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2117441_9	472759.Nhal_0859	1.585e-87	323.0	COG1159@1|root,COG1159@2|Bacteria,1QW17@1224|Proteobacteria,1T2QX@1236|Gammaproteobacteria,1WW85@135613|Chromatiales	135613|Chromatiales	S	GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
CMS3_k127_2117441_18	404589.Anae109_2940	4.054e-43	177.0	2C6CZ@1|root,32R7W@2|Bacteria,1RH5F@1224|Proteobacteria,42NQC@68525|delta/epsilon subdivisions,2WMFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868
CMS3_k127_2117441_22	1396141.BATP01000019_gene1580	3.739e-31	137.0	COG0526@1|root,COG0526@2|Bacteria,46VHM@74201|Verrucomicrobia,2IVZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_2117441_11	448385.sce0497	1.566e-81	282.0	COG2040@1|root,COG2040@2|Bacteria,1Q99A@1224|Proteobacteria,43DPD@68525|delta/epsilon subdivisions,2WZAC@28221|Deltaproteobacteria,2Z1PN@29|Myxococcales	28221|Deltaproteobacteria	H	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
CMS3_k127_2120709_11	1430440.MGMSRv2_4088	2.345e-80	291.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,2U2GS@28211|Alphaproteobacteria,2JQK5@204441|Rhodospirillales	204441|Rhodospirillales	J	Methyltransferase	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS3_k127_2120709_7	1292034.OR37_02346	3.78e-106	366.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
CMS3_k127_2120709_13	392499.Swit_2816	6.239e-51	189.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4RU@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS3_k127_2120709_2	1210884.HG799465_gene11752	3.803e-165	535.0	COG1012@1|root,COG1012@2|Bacteria,2IYRE@203682|Planctomycetes	203682|Planctomycetes	C	ketoglutarate semialdehyde dehydrogenase	-	-	1.2.1.4	ko:K14519	ko00930,ko01100,ko01120,ko01220,map00930,map01100,map01120,map01220	-	R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_2120709_9	886293.Sinac_2805	5.158e-94	338.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_2120709_3	243090.RB10503	3.456e-159	512.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_2120709_14	5762.XP_002682471.1	5.72e-32	144.0	COG2866@1|root,KOG2650@2759|Eukaryota	2759|Eukaryota	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Propep_M14
CMS3_k127_2120709_5	521674.Plim_0907	3.077e-114	379.0	COG1262@1|root,COG1262@2|Bacteria,2IYGB@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_2120709_6	493475.GARC_5284	3.336e-106	370.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,465BG@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,UnbV_ASPIC,VCBS
CMS3_k127_2120709_15	1121334.KB911067_gene313	5.512e-14	79.0	29F7N@1|root,3025B@2|Bacteria,1V7G9@1239|Firmicutes,24KI2@186801|Clostridia,3WK9D@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS3_k127_2120709_1	886293.Sinac_0575	1.143e-181	583.0	COG2268@1|root,COG2268@2|Bacteria,2IYIX@203682|Planctomycetes	203682|Planctomycetes	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
CMS3_k127_2120709_4	521674.Plim_2642	5.663e-117	384.0	COG1082@1|root,COG1082@2|Bacteria,2IWZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_2120709_8	1284352.AOIG01000016_gene4019	1.094e-100	339.0	COG0667@1|root,COG0667@2|Bacteria,1TRIU@1239|Firmicutes,4HCJC@91061|Bacilli,26QUS@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_2120709_10	497964.CfE428DRAFT_0337	7.882e-93	314.0	COG3618@1|root,COG3618@2|Bacteria,46SN7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS3_k127_2120709_12	314278.NB231_13791	6.18e-69	245.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria,1WYGC@135613|Chromatiales	135613|Chromatiales	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_2120709_0	521674.Plim_1972	3.288e-224	719.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrom_C,GSDH,HEAT_2
CMS3_k127_2123061_0	1238182.C882_1194	0.0	1357.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,2JPW3@204441|Rhodospirillales	204441|Rhodospirillales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS3_k127_2123061_6	1121033.AUCF01000004_gene5038	2.493e-59	221.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,2JRYS@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
CMS3_k127_2123061_1	1167006.UWK_01624	1.945e-137	457.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CMS3_k127_2123061_14	3067.XP_002952116.1	0.0008502	50.0	COG1109@1|root,KOG1220@2759|Eukaryota,37YCR@33090|Viridiplantae,34K2P@3041|Chlorophyta	3041|Chlorophyta	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_2123061_3	290397.Adeh_0141	9.067e-99	336.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS3_k127_2123061_2	1122939.ATUD01000001_gene577	8.103e-107	385.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2123061_9	671143.DAMO_0611	1.124e-34	149.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS3_k127_2123061_13	1396418.BATQ01000113_gene4640	1.197e-15	90.0	2E0WZ@1|root,32WDX@2|Bacteria,46WD0@74201|Verrucomicrobia,2IUTB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2123061_7	575540.Isop_3493	7.512e-49	197.0	COG0063@1|root,COG0063@2|Bacteria,2IYWH@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
CMS3_k127_2123061_5	1280390.CBQR020000013_gene345	1.314e-70	259.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,4HAM1@91061|Bacilli,26QWG@186822|Paenibacillaceae	91061|Bacilli	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
CMS3_k127_2123061_10	247490.KSU1_D0515	3.927e-27	115.0	COG1259@1|root,COG1259@2|Bacteria,2IZNE@203682|Planctomycetes	203682|Planctomycetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS3_k127_2123061_11	1123508.JH636440_gene2241	1.736e-24	108.0	2ENPA@1|root,33GAP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2123061_8	314285.KT71_08545	8.478e-46	171.0	COG1418@1|root,COG1418@2|Bacteria,1N6F4@1224|Proteobacteria,1SF9A@1236|Gammaproteobacteria,1J99R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_2123061_4	886293.Sinac_7105	1.961e-90	321.0	COG3828@1|root,COG3828@2|Bacteria,2IX0E@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,ThuA
CMS3_k127_2123061_12	452637.Oter_0997	1.675e-19	94.0	2FEB0@1|root,346AT@2|Bacteria,46W5M@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2134346_6	383372.Rcas_2573	1.142e-27	128.0	2C4KB@1|root,32YM4@2|Bacteria,2G9A1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2134346_4	1192034.CAP_3243	1.279e-30	137.0	COG4219@1|root,COG4219@2|Bacteria,1PEGJ@1224|Proteobacteria,438JW@68525|delta/epsilon subdivisions,2X3UI@28221|Deltaproteobacteria,2YX4Y@29|Myxococcales	28221|Deltaproteobacteria	DKT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS3_k127_2134346_5	1192034.CAP_3244	1.997e-29	122.0	COG3682@1|root,COG3682@2|Bacteria,1RKDI@1224|Proteobacteria,4383A@68525|delta/epsilon subdivisions,2X3DA@28221|Deltaproteobacteria,2YVI8@29|Myxococcales	28221|Deltaproteobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_2134346_8	1217718.ALOU01000030_gene1631	8.974e-09	69.0	COG0406@1|root,COG0406@2|Bacteria,1N14H@1224|Proteobacteria,2VU12@28216|Betaproteobacteria,1K8MC@119060|Burkholderiaceae	28216|Betaproteobacteria	G	alpha-ribazole phosphatase	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS3_k127_2134346_7	290397.Adeh_3181	3.268e-12	80.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42YYA@68525|delta/epsilon subdivisions,2WTU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
CMS3_k127_2134346_0	1121920.AUAU01000010_gene72	1.91e-286	910.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_2134346_1	1121403.AUCV01000006_gene404	1.054e-95	331.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2MIFW@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS3_k127_2134346_3	1123389.ATXJ01000001_gene645	1.822e-48	182.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1WIMD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS3_k127_2134346_2	1047013.AQSP01000125_gene2621	1.794e-58	212.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_2144146_2	502025.Hoch_1870	1.351e-156	522.0	COG3303@1|root,COG3303@2|Bacteria,1QXPE@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	cbcM	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_2144146_11	880073.Calab_3333	4.04e-31	138.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2144146_6	204669.Acid345_0472	2.87e-94	345.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
CMS3_k127_2144146_7	404589.Anae109_2646	2.536e-89	322.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Pyr_redox_3
CMS3_k127_2144146_15	1515746.HR45_09720	5.735e-07	60.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,2Q9HF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
CMS3_k127_2144146_4	756272.Plabr_2636	1.048e-117	394.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2144146_9	517418.Ctha_0140	1.068e-49	183.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_2144146_5	562970.Btus_2498	1.013e-107	362.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	dld	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_7,Fer4_8
CMS3_k127_2144146_1	1051632.TPY_3530	7.694e-182	576.0	COG2048@1|root,COG2048@2|Bacteria,1V67B@1239|Firmicutes,248DI@186801|Clostridia	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS3_k127_2144146_3	882083.SacmaDRAFT_1923	1.837e-140	457.0	COG1148@1|root,COG1148@2|Bacteria,2IQQS@201174|Actinobacteria	201174|Actinobacteria	C	FAD binding domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_2144146_10	882083.SacmaDRAFT_1924	1.06e-46	189.0	2DPCA@1|root,331H2@2|Bacteria,2HCYY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2144146_8	697282.Mettu_4178	1.223e-65	231.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XFY7@135618|Methylococcales	135618|Methylococcales	S	Haemolysin-III related	-	-	-	-	-	-	-	-	-	-	-	-	HlyIII
CMS3_k127_2144146_13	502025.Hoch_5537	9.921e-28	125.0	COG0452@1|root,COG0452@2|Bacteria,1RA60@1224|Proteobacteria	1224|Proteobacteria	H	PFAM flavoprotein	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CMS3_k127_2144146_14	717605.Theco_0489	7.524e-08	65.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4HF4R@91061|Bacilli,27513@186822|Paenibacillaceae	91061|Bacilli	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
CMS3_k127_2144146_12	356851.JOAN01000014_gene2111	1.39e-28	131.0	2BXSN@1|root,32R1X@2|Bacteria,2GN1N@201174|Actinobacteria,4D9R3@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
CMS3_k127_2144146_0	1499683.CCFF01000013_gene324	1.163e-187	601.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS3_k127_2157388_22	1348663.KCH_64760	2.54e-07	63.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,2M0HM@2063|Kitasatospora	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_2157388_7	234267.Acid_0456	8.583e-77	293.0	COG0745@1|root,COG0784@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,3Y62K@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_2157388_15	290512.Paes_0713	7.025e-32	129.0	COG0234@1|root,COG0234@2|Bacteria,1FE34@1090|Chlorobi	1090|Chlorobi	O	PFAM chaperonin Cpn10	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
CMS3_k127_2157388_2	1122939.ATUD01000001_gene577	1.036e-188	641.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2157388_14	1142394.PSMK_05620	6.105e-35	155.0	COG4258@1|root,COG4258@2|Bacteria,2IYH7@203682|Planctomycetes	203682|Planctomycetes	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_2157388_11	497964.CfE428DRAFT_1495	8.871e-48	190.0	COG0318@1|root,COG0318@2|Bacteria,46T7I@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2157388_9	240016.ABIZ01000001_gene5322	4.493e-63	237.0	COG0644@1|root,COG0644@2|Bacteria,46SNH@74201|Verrucomicrobia,2IVD4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CMS3_k127_2157388_21	118005.AWNK01000005_gene1662	1.752e-14	76.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_2157388_8	1131462.DCF50_p2720	8.812e-65	238.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_2157388_16	1463825.JNXC01000010_gene2774	4.37e-29	134.0	COG0304@1|root,COG0304@2|Bacteria,2GNT4@201174|Actinobacteria,4DZC5@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_2157388_19	1280948.HY36_14000	7.974e-19	102.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria,43WBC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	COG1560 Lauroyl myristoyl acyltransferase	msbB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_2157388_10	945550.VISI1226_15071	2.132e-59	230.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1Y2H6@135623|Vibrionales	135623|Vibrionales	M	COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_S8
CMS3_k127_2157388_18	1227739.Hsw_2191	3.703e-28	132.0	COG3952@1|root,COG3952@2|Bacteria,4NH8Q@976|Bacteroidetes,47YQ6@768503|Cytophagia	976|Bacteroidetes	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
CMS3_k127_2157388_6	530564.Psta_2754	1.734e-79	290.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	2|Bacteria	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	SASA
CMS3_k127_2157388_0	886293.Sinac_4467	5.721e-227	737.0	COG0304@1|root,COG0304@2|Bacteria,2IYMB@203682|Planctomycetes	203682|Planctomycetes	IQ	beta-ketoacyl-acyl-carrier-protein synthase II activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2157388_24	1255043.TVNIR_2416	7.925e-07	61.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_2157388_13	760117.JN27_16165	6.329e-44	173.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VR8T@28216|Betaproteobacteria,473F8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
CMS3_k127_2157388_1	575540.Isop_0185	3.463e-209	675.0	COG1686@1|root,COG2367@1|root,COG3409@1|root,COG1686@2|Bacteria,COG2367@2|Bacteria,COG3409@2|Bacteria,2IY9N@203682|Planctomycetes	203682|Planctomycetes	M	PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase2,PG_binding_1,Peptidase_S11
CMS3_k127_2157388_3	504472.Slin_6215	2.743e-137	451.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,47THD@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_2157388_17	237368.SCABRO_02574	2.78e-28	132.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_2157388_12	448385.sce6952	2.101e-46	193.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,1MWVZ@1224|Proteobacteria,43APJ@68525|delta/epsilon subdivisions,2X638@28221|Deltaproteobacteria,2Z38P@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2157388_4	192952.MM_3198	5.188e-127	423.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
CMS3_k127_2157388_5	1089550.ATTH01000001_gene2408	1.097e-88	312.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	2.3.1.43	ko:K00650	ko00564,ko04979,map00564,map04979	-	R02114	RC00037,RC00055	ko00000,ko00001,ko01000	-	-	-	DUF900,LCAT,Peptidase_C14
CMS3_k127_2157388_20	344747.PM8797T_13575	2.711e-18	98.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
CMS3_k127_2158727_4	324602.Caur_0649	7.644e-70	263.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_2158727_1	477974.Daud_1543	6.867e-147	499.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,260R2@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CMS3_k127_2158727_8	257310.BB0979	8.633e-10	65.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VSW6@28216|Betaproteobacteria,3T3I6@506|Alcaligenaceae	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_2158727_5	583355.Caka_0473	3.291e-64	239.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C,PA14
CMS3_k127_2158727_6	886293.Sinac_7301	2.07e-61	230.0	COG0222@1|root,COG0222@2|Bacteria,2IZS6@203682|Planctomycetes	203682|Planctomycetes	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2158727_3	1128421.JAGA01000001_gene2269	3.413e-91	309.0	COG1028@1|root,COG1028@2|Bacteria,2NQB4@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2158727_7	1123242.JH636436_gene156	4.956e-47	194.0	2AU2S@1|root,31JP5@2|Bacteria,2IZEE@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_2158727_2	479434.Sthe_2542	2.717e-91	317.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi,27XZ6@189775|Thermomicrobia	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS3_k127_2158727_10	1408324.JNJK01000001_gene567	0.0002636	53.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia,27PNE@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_2158727_0	575540.Isop_1644	1.4e-294	958.0	COG0265@1|root,COG3266@1|root,COG4447@1|root,COG0265@2|Bacteria,COG3266@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4,3.4.21.107	ko:K01179,ko:K04771	ko00500,ko01100,ko01503,ko02020,map00500,map01100,map01503,map02020	M00728	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH5,GH9	-	PDZ_2,Sortilin-Vps10,Trypsin_2
CMS3_k127_2158727_9	134676.ACPL_7364	3.327e-08	58.0	COG1317@1|root,COG1317@2|Bacteria,2H94N@201174|Actinobacteria,4DCZ2@85008|Micromonosporales	201174|Actinobacteria	NU	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2208487_12	886293.Sinac_2761	6.438e-55	218.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_2208487_8	502025.Hoch_6365	7.458e-90	305.0	COG0061@1|root,COG0061@2|Bacteria,1NBI3@1224|Proteobacteria,437ZT@68525|delta/epsilon subdivisions,2X39Q@28221|Deltaproteobacteria,2YV0Q@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2208487_6	502025.Hoch_6366	9.871e-105	350.0	COG0330@1|root,COG0330@2|Bacteria,1PEW9@1224|Proteobacteria,430NQ@68525|delta/epsilon subdivisions,2WVUU@28221|Deltaproteobacteria,2YVM2@29|Myxococcales	28221|Deltaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_2208487_9	926560.KE387023_gene2143	3.437e-87	294.0	COG1051@1|root,COG1051@2|Bacteria,1WK9S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS3_k127_2208487_15	1242864.D187_003640	8.701e-42	172.0	COG3055@1|root,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
CMS3_k127_2208487_10	1121935.AQXX01000127_gene1191	2.031e-66	248.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,1S91X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_2208487_26	886293.Sinac_5245	1.328e-11	76.0	COG4886@1|root,COG4886@2|Bacteria,2J0HP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
CMS3_k127_2208487_24	1380346.JNIH01000002_gene6370	6.608e-12	79.0	COG1225@1|root,COG1225@2|Bacteria,2IFB1@201174|Actinobacteria	201174|Actinobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_2208487_1	344747.PM8797T_24611	4.082e-258	823.0	COG2133@1|root,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_2208487_30	378806.STAUR_4755	0.0002849	54.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria,2YYWS@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2208487_27	944560.HMPREF9058_1116	2.622e-09	71.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4D4ET@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2208487_23	1380355.JNIJ01000010_gene1555	1.724e-15	87.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria,3JUZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2208487_22	530564.Psta_2697	4.963e-24	119.0	COG1413@1|root,COG1520@1|root,COG1413@2|Bacteria,COG1520@2|Bacteria,2J3VN@203682|Planctomycetes	2|Bacteria	C	HEAT repeats	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	DNA_alkylation,HEAT_2,MFS_1,PQQ_2,cNMP_binding
CMS3_k127_2208487_29	62928.azo0278	1.363e-05	57.0	2EFNF@1|root,339EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2208487_16	1123508.JH636443_gene4728	1.106e-41	177.0	COG4219@1|root,COG4219@2|Bacteria,2J24Z@203682|Planctomycetes	203682|Planctomycetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS3_k127_2208487_21	1123508.JH636448_gene7570	7.636e-29	121.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_2208487_5	583355.Caka_2440	1.847e-132	449.0	COG0514@1|root,COG0514@2|Bacteria,46S7V@74201|Verrucomicrobia,3K7AV@414999|Opitutae	414999|Opitutae	L	ATP-dependent DNA helicase RecQ	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS3_k127_2208487_25	1167006.UWK_01962	1.069e-11	77.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_2208487_3	314230.DSM3645_02313	2.79e-160	529.0	COG4409@1|root,COG4409@2|Bacteria,2IYG9@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,BNR_assoc_N
CMS3_k127_2208487_2	756272.Plabr_4157	4.443e-223	707.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2208487_14	314278.NB231_11949	3.437e-42	162.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria,1X1G0@135613|Chromatiales	135613|Chromatiales	S	Acyl carrier protein phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
CMS3_k127_2208487_11	1286632.P278_24970	4.648e-61	225.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1HXKC@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_2208487_4	335543.Sfum_1629	6.501e-141	460.0	28JVF@1|root,2Z9KD@2|Bacteria,1MXZ6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2208487_13	335543.Sfum_1630	4.463e-50	196.0	28HJ1@1|root,2Z7UB@2|Bacteria,1R3FN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2208487_18	1122962.AULH01000008_gene2268	2.397e-37	164.0	COG1196@1|root,COG1196@2|Bacteria,1MXPN@1224|Proteobacteria,2TRG3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2208487_20	1448389.BAVQ01000006_gene3241	3.423e-31	139.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2208487_19	314271.RB2654_06724	3.074e-33	147.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_2208487_0	717605.Theco_2421	5e-324	1015.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26QCH@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS3_k127_2208487_28	595460.RRSWK_05083	7.772e-06	53.0	COG0582@1|root,COG0582@2|Bacteria,2IYXX@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS3_k127_2208487_7	1122939.ATUD01000001_gene577	1.246e-97	342.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2209989_1	1167006.UWK_00567	1.581e-101	349.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_2209989_4	1123371.ATXH01000001_gene1285	3.132e-10	71.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	slt	-	-	ko:K07114,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.A.13.2.2,1.A.13.2.3	GH23	-	SLT,TPR_16,TPR_6
CMS3_k127_2209989_5	391625.PPSIR1_20654	4.721e-05	55.0	COG3899@1|root,COG4191@1|root,COG3899@2|Bacteria,COG4191@2|Bacteria,1R609@1224|Proteobacteria,42MTJ@68525|delta/epsilon subdivisions,2WJYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Pkinase
CMS3_k127_2209989_3	880073.Calab_1268	1.195e-34	150.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
CMS3_k127_2209989_2	1167006.UWK_00561	1.646e-36	147.0	COG3303@1|root,COG3303@2|Bacteria,1NX4E@1224|Proteobacteria,431QJ@68525|delta/epsilon subdivisions,2WWSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_2209989_0	247490.KSU1_B0001	6.281e-109	369.0	COG2204@1|root,COG2204@2|Bacteria,2IY95@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2233106_1	1047013.AQSP01000099_gene1492	9.847e-66	237.0	COG2103@1|root,COG2103@2|Bacteria	2|Bacteria	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_2233106_6	794903.OPIT5_05955	8.007e-18	95.0	2DD1T@1|root,2ZG67@2|Bacteria,46YN3@74201|Verrucomicrobia,3K9V4@414999|Opitutae	414999|Opitutae	-	-	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_2233106_2	713586.KB900536_gene469	1.517e-65	241.0	COG0477@1|root,COG2814@2|Bacteria,1RCII@1224|Proteobacteria	1224|Proteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2233106_4	1306174.JODP01000009_gene6471	9.298e-23	104.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS3_k127_2233106_8	1095769.CAHF01000023_gene574	5.817e-13	81.0	COG3420@1|root,COG3420@2|Bacteria,1QA33@1224|Proteobacteria,2WD4B@28216|Betaproteobacteria,476MW@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Protein of unknown function (DUF1565)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
CMS3_k127_2233106_0	880073.Calab_1185	1.553e-239	771.0	COG0013@1|root,COG0013@2|Bacteria,2NNYC@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_2233106_5	1284352.AOIG01000013_gene3550	1.53e-22	114.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
CMS3_k127_2233106_3	314230.DSM3645_22174	5.304e-61	221.0	COG2081@1|root,COG2081@2|Bacteria,2IWW4@203682|Planctomycetes	203682|Planctomycetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS3_k127_2258787_1	1444711.CCJF01000005_gene546	2.87e-83	308.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta,SBBP
CMS3_k127_2258787_5	391625.PPSIR1_12803	4.443e-14	87.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2258787_6	391625.PPSIR1_37349	3.227e-09	71.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_2258787_8	253839.SSNG_00184	0.0001356	53.0	COG0840@1|root,COG0840@2|Bacteria,2I2WI@201174|Actinobacteria	201174|Actinobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP
CMS3_k127_2258787_7	448385.sce1844	9.519e-09	69.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_2258787_0	2903.EOD39316	8.397e-105	355.0	2B1ZI@1|root,2S0BK@2759|Eukaryota	2759|Eukaryota	S	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS3_k127_2258787_4	595460.RRSWK_03903	1.85e-14	85.0	2C57D@1|root,2Z7RS@2|Bacteria,2IZEG@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
CMS3_k127_2258787_3	1122604.JONR01000007_gene2935	6.329e-15	84.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
CMS3_k127_2258787_2	1297742.A176_04807	4.56e-25	122.0	COG1470@1|root,COG1470@2|Bacteria,1MZXY@1224|Proteobacteria,432M7@68525|delta/epsilon subdivisions,2WXW8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
CMS3_k127_2292566_6	710421.Mycch_1193	3.751e-05	57.0	COG2373@1|root,COG3391@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2GK45@201174|Actinobacteria,2366T@1762|Mycobacteriaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Lactonase
CMS3_k127_2292566_2	243090.RB2752	3.011e-60	216.0	COG0500@1|root,COG2226@2|Bacteria,2IYWE@203682|Planctomycetes	203682|Planctomycetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_2292566_4	314230.DSM3645_15955	5.56e-19	96.0	COG1266@1|root,COG1266@2|Bacteria,2J06D@203682|Planctomycetes	203682|Planctomycetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2292566_3	1120973.AQXL01000134_gene1529	8.654e-53	203.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,2789X@186823|Alicyclobacillaceae	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CMS3_k127_2292566_1	886293.Sinac_1699	2.203e-64	243.0	COG0382@1|root,COG0382@2|Bacteria,2IX4Z@203682|Planctomycetes	203682|Planctomycetes	H	COG0382 4-hydroxybenzoate polyprenyltransferase and related	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_2292566_5	266117.Rxyl_1518	4.305e-09	70.0	COG1466@1|root,COG1466@2|Bacteria,2HNE7@201174|Actinobacteria,4CP84@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS3_k127_2292566_0	314230.DSM3645_19987	2.447e-119	413.0	COG0323@1|root,COG0323@2|Bacteria,2IXI2@203682|Planctomycetes	203682|Planctomycetes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS3_k127_2297662_0	1122604.JONR01000013_gene3239	1.827e-101	338.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_2297662_1	765952.PUV_16910	2.416e-58	217.0	COG0820@1|root,COG0820@2|Bacteria	2|Bacteria	J	rRNA (adenine-C2-)-methyltransferase activity	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192,2.1.1.224	ko:K06941,ko:K15632	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_2297662_2	595460.RRSWK_06213	1.805e-24	108.0	COG0463@1|root,COG1807@1|root,COG0463@2|Bacteria,COG1807@2|Bacteria,2IZ8J@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 39	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
CMS3_k127_2298838_0	243090.RB5146	1.414e-219	694.0	COG3119@1|root,COG3119@2|Bacteria,2IY4T@203682|Planctomycetes	203682|Planctomycetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CMS3_k127_2298838_1	1121957.ATVL01000011_gene3699	1.078e-127	445.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
CMS3_k127_2298838_4	204669.Acid345_0181	1.668e-05	51.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia	204432|Acidobacteriia	CO	Glutathione peroxidase	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
CMS3_k127_2298838_2	1242864.D187_002131	8.675e-78	271.0	COG3382@1|root,COG3382@2|Bacteria,1N6A7@1224|Proteobacteria,4337M@68525|delta/epsilon subdivisions,2WXR0@28221|Deltaproteobacteria,2YUZ2@29|Myxococcales	28221|Deltaproteobacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
CMS3_k127_2298838_3	518766.Rmar_2419	9.582e-27	111.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1FKAC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_2300701_5	344747.PM8797T_13625	6.575e-149	478.0	2DBUK@1|root,2ZB6C@2|Bacteria,2IYA3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2300701_4	1396141.BATP01000003_gene4967	7.686e-165	586.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
CMS3_k127_2300701_0	1185876.BN8_01964	0.0	1637.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHMI@976|Bacteroidetes,47K6B@768503|Cytophagia	976|Bacteroidetes	CG	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2,PmoA
CMS3_k127_2300701_2	1123070.KB899249_gene358	1.809e-206	655.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CMS3_k127_2300701_1	1123228.AUIH01000043_gene1793	3.206e-231	727.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,1XIUD@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the glutamate synthase family	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase,zf-CDGSH
CMS3_k127_2300701_3	497964.CfE428DRAFT_6648	3.091e-165	534.0	COG3119@1|root,COG3119@2|Bacteria,46UMG@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CMS3_k127_2300701_13	290397.Adeh_4027	2.887e-13	84.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2300701_12	234267.Acid_2321	2.19e-13	84.0	COG1595@1|root,COG1595@2|Bacteria,3Y45G@57723|Acidobacteria	2|Bacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2300701_6	1515746.HR45_00600	1.609e-88	319.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,2QA7M@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
CMS3_k127_2300701_9	335541.Swol_1711	1.137e-63	226.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,25MYX@186801|Clostridia,42KTR@68298|Syntrophomonadaceae	186801|Clostridia	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS3_k127_2300701_7	1411123.JQNH01000001_gene2190	3.413e-81	285.0	COG3540@1|root,COG3540@2|Bacteria,1R5RU@1224|Proteobacteria,2U4KZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG3540 Phosphodiesterase alkaline phosphatase D	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
CMS3_k127_2300701_17	595460.RRSWK_04976	1.579e-05	57.0	COG1595@1|root,COG1595@2|Bacteria,2IZFC@203682|Planctomycetes	203682|Planctomycetes	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
CMS3_k127_2300701_8	1210884.HG799471_gene14563	1.333e-79	296.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2300701_14	525904.Tter_2775	2.974e-10	76.0	COG3420@1|root,COG3420@2|Bacteria,2NRSC@2323|unclassified Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Beta_helix,DUF3747,Laminin_G_3,NosD,PQQ_3
CMS3_k127_2300701_11	1137271.AZUM01000015_gene1665	6.168e-22	114.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DYIP@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_2300701_10	1281779.H009_06382	4.21e-36	154.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2TQUH@28211|Alphaproteobacteria,4BBYY@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	amine oxidase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
CMS3_k127_2300701_16	1123065.ATWL01000005_gene1228	6.857e-09	69.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2300701_18	1487953.JMKF01000048_gene2069	0.0001579	50.0	COG2197@1|root,COG2197@2|Bacteria,1G1TZ@1117|Cyanobacteria,1H7FH@1150|Oscillatoriales	1117|Cyanobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	ycf29	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_2300701_15	1232437.KL661988_gene243	4.505e-09	69.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MHXT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,GAF_2,HAMP,HATPase_c,HisKA,Hpt,MASE2,PAS_4,PAS_9,Response_reg
CMS3_k127_2311126_16	700598.Niako_2052	6.991e-114	376.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,1IP2T@117747|Sphingobacteriia	976|Bacteroidetes	P	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
CMS3_k127_2311126_10	7739.XP_002595086.1	1.331e-152	497.0	COG2233@1|root,KOG1292@2759|Eukaryota,39CFN@33154|Opisthokonta,3BCH2@33208|Metazoa,3CSWQ@33213|Bilateria,483M7@7711|Chordata	33208|Metazoa	F	sodium-dependent L-ascorbate transmembrane transporter activity	SLC23A2	GO:0003674,GO:0005215,GO:0005342,GO:0005343,GO:0005402,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0005903,GO:0005975,GO:0005996,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008324,GO:0008509,GO:0008514,GO:0008520,GO:0008643,GO:0009636,GO:0009925,GO:0009987,GO:0015075,GO:0015077,GO:0015081,GO:0015144,GO:0015145,GO:0015205,GO:0015229,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015672,GO:0015711,GO:0015749,GO:0015849,GO:0015851,GO:0015882,GO:0016020,GO:0016021,GO:0016323,GO:0016324,GO:0019752,GO:0019852,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030323,GO:0030324,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0033300,GO:0034219,GO:0034220,GO:0034641,GO:0035295,GO:0035461,GO:0035725,GO:0042221,GO:0043226,GO:0043229,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045177,GO:0045178,GO:0046483,GO:0046873,GO:0046942,GO:0046943,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051119,GO:0051179,GO:0051180,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051186,GO:0051234,GO:0055085,GO:0060322,GO:0060541,GO:0070633,GO:0070837,GO:0070890,GO:0070904,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0090482,GO:0098590,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:0098862,GO:1901360,GO:1903825,GO:1905039	-	ko:K14611	-	-	-	-	ko00000,ko02000	2.A.40.6	-	-	Xan_ur_permease
CMS3_k127_2311126_22	886293.Sinac_1726	4.197e-58	207.0	COG0231@1|root,COG0231@2|Bacteria,2IZCU@203682|Planctomycetes	203682|Planctomycetes	J	Elongation factor P (EF-P) OB domain	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS3_k127_2311126_21	1380391.JIAS01000011_gene5490	5.023e-81	278.0	COG1082@1|root,COG1082@2|Bacteria,1R87Z@1224|Proteobacteria,2U45F@28211|Alphaproteobacteria,2JUT7@204441|Rhodospirillales	204441|Rhodospirillales	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_2311126_23	452637.Oter_2251	1.062e-39	161.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS3_k127_2311126_24	755732.Fluta_0088	9.408e-20	104.0	COG0457@1|root,COG0457@2|Bacteria,4NI5H@976|Bacteroidetes,1I5EH@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
CMS3_k127_2311126_20	240016.ABIZ01000001_gene1603	1.184e-82	299.0	COG0348@1|root,COG0348@2|Bacteria,46UK4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
CMS3_k127_2311126_0	314230.DSM3645_08677	4.917e-303	973.0	COG1249@1|root,COG1249@2|Bacteria,2IYMR@203682|Planctomycetes	203682|Planctomycetes	C	Glucose inhibited division protein A	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS3_k127_2311126_26	272123.Anacy_3418	3.806e-15	86.0	COG1266@1|root,COG1266@2|Bacteria,1G5HB@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CAAX amino terminal protease family	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2311126_2	595460.RRSWK_01935	4.81e-258	804.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_2311126_18	583355.Caka_1355	1.769e-95	330.0	COG0654@1|root,COG0654@2|Bacteria,46VIV@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_2311126_6	378806.STAUR_8046	4.879e-202	637.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,42YD3@68525|delta/epsilon subdivisions,2WTVV@28221|Deltaproteobacteria,2YU0M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	yeiA	-	1.3.1.1	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
CMS3_k127_2311126_13	1192034.CAP_8586	1.285e-135	445.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,2YUCU@29|Myxococcales	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS3_k127_2311126_9	378806.STAUR_8044	8.898e-168	539.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YWB2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_2311126_5	1254432.SCE1572_37905	4.553e-214	688.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42PXH@68525|delta/epsilon subdivisions,2WKEX@28221|Deltaproteobacteria,2YTWX@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
CMS3_k127_2311126_11	1192034.CAP_8584	1.321e-149	477.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WP4Z@28221|Deltaproteobacteria,2YU7V@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS3_k127_2311126_8	1254432.SCE1572_37920	2.956e-174	592.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YUP4@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_2311126_15	344747.PM8797T_16735	6.37e-118	406.0	COG0501@1|root,COG0501@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS3_k127_2311126_4	502025.Hoch_2603	9.301e-216	690.0	COG0167@1|root,COG0479@1|root,COG0167@2|Bacteria,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.1.1,1.3.1.2,1.97.1.9	ko:K00207,ko:K12527,ko:K17723	ko00240,ko00410,ko00450,ko00770,ko00983,ko01100,map00240,map00410,map00450,map00770,map00983,map01100	M00046	R00977,R00978,R01414,R01415,R07229,R08226,R11026	RC00072,RC00123,RC02245,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	ATC_hydrolase,CCG,DHO_dh,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_20,Fer4_8,Pyr_redox_2
CMS3_k127_2311126_25	404589.Anae109_4442	3.694e-17	94.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
CMS3_k127_2311126_27	1348908.KI518588_gene2016	2.673e-05	55.0	COG1994@1|root,COG1994@2|Bacteria,1U9NJ@1239|Firmicutes,4IJU8@91061|Bacilli,1ZPSN@1386|Bacillus	91061|Bacilli	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2311126_19	502025.Hoch_3413	4.526e-95	338.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WP4Z@28221|Deltaproteobacteria,2YU7V@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS3_k127_2311126_12	502025.Hoch_6670	7.406e-143	472.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,42MTD@68525|delta/epsilon subdivisions,2WMRP@28221|Deltaproteobacteria,2Z0YS@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_2311126_14	1408428.JNJP01000068_gene1266	1.306e-130	429.0	COG0402@1|root,COG0402@2|Bacteria,1Q1P7@1224|Proteobacteria,42U3F@68525|delta/epsilon subdivisions,2WR49@28221|Deltaproteobacteria,2MF5Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_2311126_3	1122963.AUHB01000002_gene954	1.929e-232	746.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,371JF@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
CMS3_k127_2311126_7	1499967.BAYZ01000188_gene3892	3.31e-192	610.0	COG0031@1|root,COG0031@2|Bacteria,2NNZI@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47,6.2.1.30	ko:K01738,ko:K01912	ko00270,ko00360,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko05111,map00270,map00360,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map05111	M00021	R00897,R02539,R03601,R04859	RC00004,RC00014,RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2311126_17	498761.HM1_2697	2.478e-113	379.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia	186801|Clostridia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_2311126_1	1089547.KB913013_gene3957	2.517e-264	828.0	COG4631@1|root,COG4631@2|Bacteria,4PMEG@976|Bacteroidetes,47KPG@768503|Cytophagia	976|Bacteroidetes	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_2349277_10	331869.BAL199_26557	2.08e-68	244.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,4BPGW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS3_k127_2349277_6	886293.Sinac_0410	9.212e-99	358.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_2349277_8	273068.TTE2334	9.962e-82	300.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS3_k127_2349277_12	404589.Anae109_0783	6.746e-56	221.0	COG0122@1|root,COG0122@2|Bacteria,1P0FP@1224|Proteobacteria	1224|Proteobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS3_k127_2349277_3	314230.DSM3645_24550	3.418e-110	371.0	COG0042@1|root,COG0042@2|Bacteria,2IYH0@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
CMS3_k127_2349277_22	1123242.JH636436_gene395	1.199e-25	123.0	COG3219@1|root,COG3219@2|Bacteria,2J0EG@203682|Planctomycetes	203682|Planctomycetes	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
CMS3_k127_2349277_4	521674.Plim_3267	2.088e-107	363.0	COG3220@1|root,COG3220@2|Bacteria,2IY8B@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
CMS3_k127_2349277_28	682795.AciX8_4093	1.856e-07	60.0	2EQ9A@1|root,33HVF@2|Bacteria,3Y5PI@57723|Acidobacteria,2JJZM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349277_14	1123504.JQKD01000005_gene4773	1.279e-51	187.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,2VQZM@28216|Betaproteobacteria,4ADQK@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_2349277_31	313603.FB2170_04015	0.0006415	53.0	COG2755@1|root,COG4244@1|root,COG2755@2|Bacteria,COG4244@2|Bacteria,4NG6K@976|Bacteroidetes,1HZ9V@117743|Flavobacteriia	976|Bacteroidetes	E	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_2349277_29	756272.Plabr_4631	1.121e-06	62.0	COG2010@1|root,COG2010@2|Bacteria,2J21K@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_2349277_1	1123368.AUIS01000002_gene1535	3.663e-123	408.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,2NCHN@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_2349277_16	1131269.AQVV01000013_gene1741	9.285e-45	181.0	COG5036@1|root,COG5036@2|Bacteria	2|Bacteria	P	cellular response to phosphate starvation	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS3_k127_2349277_2	1131269.AQVV01000013_gene1742	4.178e-121	430.0	28JA7@1|root,2Z951@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_2349277_13	1131269.AQVV01000013_gene1743	4.832e-52	195.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CMS3_k127_2349277_17	857293.CAAU_0418	1.172e-44	184.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,36DF6@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
CMS3_k127_2349277_23	1121439.dsat_1905	4.77e-20	99.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS3_k127_2349277_21	1121878.AUGL01000002_gene2158	7.129e-27	118.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	arsenate reductase	arsC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS3_k127_2349277_24	1304878.AUGD01000003_gene2376	9.043e-17	86.0	2CGEX@1|root,32U4B@2|Bacteria,1MWWW@1224|Proteobacteria,2TT01@28211|Alphaproteobacteria,3JSQK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1579)	MA20_43845	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS3_k127_2349277_11	1108045.GORHZ_073_00030	1.205e-57	229.0	COG0457@1|root,COG2885@1|root,COG2931@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,COG2931@2|Bacteria,2IBAR@201174|Actinobacteria	201174|Actinobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349277_18	997296.PB1_10899	3.527e-43	183.0	COG0584@1|root,COG3540@1|root,COG0584@2|Bacteria,COG3540@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,1ZPVG@1386|Bacillus	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,PhoD,PhoD_N
CMS3_k127_2349277_20	448385.sce0265	1.334e-33	136.0	2C1S9@1|root,32R0M@2|Bacteria,1NDIC@1224|Proteobacteria,43212@68525|delta/epsilon subdivisions,2WWWU@28221|Deltaproteobacteria,2Z22Y@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349277_30	448385.sce0265	0.0003204	50.0	2C1S9@1|root,32R0M@2|Bacteria,1NDIC@1224|Proteobacteria,43212@68525|delta/epsilon subdivisions,2WWWU@28221|Deltaproteobacteria,2Z22Y@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349277_7	1121920.AUAU01000018_gene1826	9.762e-94	325.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
CMS3_k127_2349277_15	247490.KSU1_C1665	2.565e-49	198.0	2EBFT@1|root,335GE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349277_19	234267.Acid_5023	2.022e-42	180.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2349277_9	1173026.Glo7428_2160	4.869e-80	273.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2349277_26	595460.RRSWK_00675	6.938e-13	81.0	28N64@1|root,2ZBFG@2|Bacteria,2IYGV@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase of plants and bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BSP
CMS3_k127_2349277_5	1123065.ATWL01000006_gene2307	6.793e-102	365.0	COG1082@1|root,COG1082@2|Bacteria,2I94Z@201174|Actinobacteria	201174|Actinobacteria	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS3_k127_2349277_0	591157.SSLG_01417	1.238e-160	516.0	COG0174@1|root,COG0174@2|Bacteria,2GKU9@201174|Actinobacteria	201174|Actinobacteria	E	glutamine synthetase	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_2364782_0	251221.35214774	4.807e-81	294.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
CMS3_k127_2364782_1	1266925.JHVX01000002_gene989	1.019e-42	169.0	COG3675@1|root,COG3675@2|Bacteria,1ND8U@1224|Proteobacteria,2W674@28216|Betaproteobacteria,374IY@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
CMS3_k127_2364782_2	68260.JOAY01000086_gene2487	3.902e-07	63.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_2383547_6	554065.XP_005845791.1	0.0001422	45.0	COG1231@1|root,KOG0029@2759|Eukaryota,388PY@33090|Viridiplantae,34PC5@3041|Chlorophyta	3041|Chlorophyta	Q	Flavin containing amine oxidoreductase	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS3_k127_2383547_2	204669.Acid345_1269	1.392e-123	410.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS3_k127_2383547_0	204669.Acid345_1270	5.084e-217	708.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
CMS3_k127_2383547_3	234267.Acid_7336	1.77e-91	337.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_2383547_4	886293.Sinac_3618	8.582e-86	318.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_2383547_1	521674.Plim_3536	3.186e-130	426.0	COG3345@1|root,COG3345@2|Bacteria,2J1YM@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_2383547_5	1122603.ATVI01000007_gene1691	7.259e-38	142.0	COG2813@1|root,COG2813@2|Bacteria,1QWWU@1224|Proteobacteria,1T5SK@1236|Gammaproteobacteria,1XARZ@135614|Xanthomonadales	1224|Proteobacteria	J	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS3_k127_2387936_4	448385.sce7172	3.578e-53	192.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1R2T0@1224|Proteobacteria,43BXM@68525|delta/epsilon subdivisions,2X78E@28221|Deltaproteobacteria,2YUMW@29|Myxococcales	28221|Deltaproteobacteria	V	Peptidase C39 family	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran,Peptidase_C39
CMS3_k127_2387936_1	215803.DB30_1661	2.576e-164	549.0	COG1132@1|root,COG1132@2|Bacteria,1NRJ2@1224|Proteobacteria,437FW@68525|delta/epsilon subdivisions,2X2NG@28221|Deltaproteobacteria,2YTZX@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
CMS3_k127_2387936_2	314278.NB231_00260	2.13e-141	457.0	KOG2165@1|root,2Z911@2|Bacteria,1N8JM@1224|Proteobacteria,1RR9Z@1236|Gammaproteobacteria,1WWIT@135613|Chromatiales	135613|Chromatiales	S	ubiquitin protein ligase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2387936_0	472759.Nhal_3586	9.68e-282	881.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X0IX@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_2387936_3	472759.Nhal_3587	1.218e-107	361.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria,1X0FH@135613|Chromatiales	135613|Chromatiales	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_2401381_3	314271.RB2654_10713	3.836e-61	232.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_2401381_4	935839.JAGJ01000009_gene520	3.432e-20	106.0	COG3291@1|root,COG3507@1|root,COG3525@1|root,COG3291@2|Bacteria,COG3507@2|Bacteria,COG3525@2|Bacteria,2GK90@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase family 20, catalytic	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Big_2,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,NPCBM_assoc,RicinB_lectin_2
CMS3_k127_2401381_0	595460.RRSWK_07152	1.927e-152	505.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM,NPCBM_assoc,Sulfatase
CMS3_k127_2401381_2	382464.ABSI01000011_gene2353	2.934e-84	301.0	COG1538@1|root,COG1538@2|Bacteria,46WHQ@74201|Verrucomicrobia,2IW13@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_2401381_1	382464.ABSI01000005_gene973	2.397e-137	483.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
CMS3_k127_2407700_10	1124780.ANNU01000030_gene1155	1.741e-07	62.0	COG1305@1|root,COG1305@2|Bacteria,4NE7G@976|Bacteroidetes,47JVH@768503|Cytophagia	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
CMS3_k127_2407700_2	449447.MAE_11280	1.136e-60	218.0	COG0639@1|root,COG0639@2|Bacteria,1G4GG@1117|Cyanobacteria	1117|Cyanobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
CMS3_k127_2407700_1	448385.sce1266	6.356e-74	265.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
CMS3_k127_2407700_3	1121033.AUCF01000004_gene4659	1.018e-53	199.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,2JSB2@204441|Rhodospirillales	204441|Rhodospirillales	O	Peptidase family M48	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS3_k127_2407700_9	344747.PM8797T_31608	5.093e-14	85.0	COG2304@1|root,COG2304@2|Bacteria,2IZSI@203682|Planctomycetes	203682|Planctomycetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_2407700_7	322710.Avin_46560	1.729e-19	102.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,1RPP2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_2407700_4	1211115.ALIQ01000212_gene3277	1.504e-50	194.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,3NAHN@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	phoB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2407700_5	234267.Acid_7897	1.488e-40	174.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2407700_0	82654.Pse7367_3306	1.311e-150	509.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1GQI2@1117|Cyanobacteria	1117|Cyanobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
CMS3_k127_2407700_8	1304275.C41B8_16724	2.098e-19	89.0	COG4968@1|root,COG4968@2|Bacteria,1N31J@1224|Proteobacteria,1SS17@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS3_k127_2426082_1	1121945.ATXS01000001_gene2540	2.914e-16	89.0	COG3402@1|root,arCOG04622@2157|Archaea,2XXVX@28890|Euryarchaeota,23W3G@183963|Halobacteria	183963|Halobacteria	S	Membrane-flanked domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
CMS3_k127_2426082_0	649747.HMPREF0083_01807	4.83e-22	111.0	COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,26R5D@186822|Paenibacillaceae	91061|Bacilli	S	Bacterial PH domain	ydbT	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
CMS3_k127_245892_2	1353529.M899_1106	1.133e-28	121.0	COG0035@1|root,COG0035@2|Bacteria,1RBD6@1224|Proteobacteria,42R1E@68525|delta/epsilon subdivisions,2MTMR@213481|Bdellovibrionales,2WN3Q@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Uracil phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UPRTase
CMS3_k127_245892_1	1408254.T458_25500	3.05e-38	149.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,26SCN@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,6.3.4.19	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000,ko03016	-	-	-	Pribosyltran
CMS3_k127_245892_0	1242864.D187_003764	4.007e-145	486.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,437F6@68525|delta/epsilon subdivisions,2X2MS@28221|Deltaproteobacteria,2YTV3@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CMS3_k127_2472542_12	234267.Acid_1208	3.809e-27	129.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_2472542_15	285535.JOEY01000095_gene4026	7.143e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2472542_2	1237149.C900_00402	2.027e-73	258.0	COG0596@1|root,COG0596@2|Bacteria,4PNPN@976|Bacteroidetes,47XAU@768503|Cytophagia	976|Bacteroidetes	S	Ndr family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS3_k127_2472542_1	1396418.BATQ01000185_gene2137	3.339e-168	541.0	COG0673@1|root,COG0673@2|Bacteria,46U2Q@74201|Verrucomicrobia,2IV92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_2472542_5	396588.Tgr7_2596	4.004e-55	205.0	2DJ8V@1|root,3050U@2|Bacteria,1RE7U@1224|Proteobacteria,1SNMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	-
CMS3_k127_2472542_17	443255.SCLAV_5510	2.228e-10	75.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2472542_16	1144275.COCOR_01518	1.184e-12	82.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_2472542_19	3075.A0A087SIQ9	2.337e-06	61.0	KOG1947@1|root,KOG1947@2759|Eukaryota	2759|Eukaryota	B	F-box LRR-repeat protein	-	-	-	ko:K10268,ko:K10273,ko:K10279,ko:K10280,ko:K14515	ko04016,ko04075,map04016,map04075	-	-	-	ko00000,ko00001,ko04121	-	-	-	LRR_6
CMS3_k127_2472542_13	243090.RB12730	3.365e-20	97.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2472542_9	395961.Cyan7425_2716	4.7e-42	179.0	2EYR6@1|root,33RYI@2|Bacteria,1GBIS@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2472542_4	1265505.ATUG01000001_gene4606	6.812e-66	236.0	COG3409@1|root,COG3409@2|Bacteria,1RBD0@1224|Proteobacteria	1224|Proteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
CMS3_k127_2472542_8	757424.Hsero_1329	6.488e-44	168.0	COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,2VIPM@28216|Betaproteobacteria,4760U@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_2472542_18	269084.syc0757_d	6.004e-08	65.0	COG0515@1|root,COG0515@2|Bacteria,1G02X@1117|Cyanobacteria,1H3YP@1129|Synechococcus	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2472542_11	1121405.dsmv_0582	3.402e-32	144.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2MK47@213118|Desulfobacterales	28221|Deltaproteobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_2472542_14	1340493.JNIF01000003_gene3422	7.996e-20	94.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2472542_6	1379270.AUXF01000005_gene519	3.584e-45	180.0	COG4409@1|root,COG4409@2|Bacteria,1ZUBR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2472542_3	404589.Anae109_0629	9.884e-67	238.0	COG1232@1|root,COG1232@2|Bacteria,1R5SZ@1224|Proteobacteria,42YX0@68525|delta/epsilon subdivisions,2WTXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS3_k127_2482988_16	1379270.AUXF01000007_gene963	1.219e-49	187.0	COG0006@1|root,COG0006@2|Bacteria,1ZUQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_2482988_35	929703.KE386491_gene2985	2.502e-13	84.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
CMS3_k127_2482988_13	1123242.JH636435_gene2487	1.413e-55	222.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_2482988_45	1169152.AXVD01000033_gene3598	0.0005205	52.0	29XDQ@1|root,30J3Q@2|Bacteria,2I67U@201174|Actinobacteria,4G4FX@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
CMS3_k127_2482988_30	1210884.HG799466_gene12935	1.033e-16	94.0	COG1595@1|root,COG1595@2|Bacteria,2J35E@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_2482988_26	269799.Gmet_0085	3.597e-30	127.0	COG2365@1|root,COG2365@2|Bacteria,1N0NB@1224|Proteobacteria,43CF8@68525|delta/epsilon subdivisions,2X60D@28221|Deltaproteobacteria,43UY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
CMS3_k127_2482988_0	1122176.KB903539_gene1357	0.0	1197.0	COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,1INYW@117747|Sphingobacteriia	976|Bacteroidetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_2482988_34	1254432.SCE1572_30245	2.319e-13	80.0	2CB8J@1|root,32WAQ@2|Bacteria,1P5YB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2482988_39	1278073.MYSTI_05271	4.357e-08	61.0	COG1544@1|root,COG1544@2|Bacteria,1N8CQ@1224|Proteobacteria,4387F@68525|delta/epsilon subdivisions,2X3HC@28221|Deltaproteobacteria,2YW3C@29|Myxococcales	28221|Deltaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
CMS3_k127_2482988_31	448385.sce1844	7.704e-15	90.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_2482988_36	886293.Sinac_2497	1.405e-12	82.0	COG1595@1|root,COG2373@1|root,COG1595@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K03088,ko:K06894	-	-	-	-	ko00000,ko03021	-	-	-	A2M_N,CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
CMS3_k127_2482988_3	489825.LYNGBM3L_21180	8.813e-139	460.0	COG0438@1|root,COG0438@2|Bacteria,1GCX5@1117|Cyanobacteria	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2482988_33	391625.PPSIR1_20349	1.304e-13	85.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_2482988_9	244447.XP_008335183.1	2.019e-79	276.0	COG0580@1|root,KOG0224@2759|Eukaryota,392UK@33154|Opisthokonta,3BF70@33208|Metazoa,3CSKK@33213|Bilateria,482G3@7711|Chordata,494XA@7742|Vertebrata,49XNR@7898|Actinopterygii	33208|Metazoa	G	Belongs to the MIP aquaporin (TC 1.A.8) family	AQP9	GO:0002376,GO:0003008,GO:0003674,GO:0005215,GO:0005275,GO:0005342,GO:0005345,GO:0005350,GO:0005372,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006833,GO:0006863,GO:0006869,GO:0006950,GO:0006952,GO:0006955,GO:0006970,GO:0007588,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009719,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010876,GO:0014070,GO:0014074,GO:0015075,GO:0015144,GO:0015166,GO:0015168,GO:0015204,GO:0015205,GO:0015250,GO:0015254,GO:0015265,GO:0015267,GO:0015288,GO:0015318,GO:0015711,GO:0015718,GO:0015721,GO:0015722,GO:0015791,GO:0015793,GO:0015837,GO:0015840,GO:0015849,GO:0015850,GO:0015851,GO:0015855,GO:0016020,GO:0016021,GO:0016323,GO:0019755,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032501,GO:0033036,GO:0034219,GO:0034220,GO:0042044,GO:0042221,GO:0042592,GO:0042742,GO:0042886,GO:0042887,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045087,GO:0046683,GO:0046689,GO:0046717,GO:0046903,GO:0046942,GO:0046943,GO:0048878,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051591,GO:0051704,GO:0051707,GO:0051716,GO:0055085,GO:0065007,GO:0065008,GO:0070887,GO:0071310,GO:0071320,GO:0071407,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:0071918,GO:0071944,GO:0072530,GO:0072531,GO:0098542,GO:0098590,GO:0098656,GO:1901618,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903825,GO:1904823,GO:1905039	-	ko:K09876,ko:K09877,ko:K09878,ko:K09886,ko:K10404	ko04962,ko04976,map04962,map04976	-	-	-	ko00000,ko00001,ko02000,ko04812	1.A.8,1.A.8.9	-	-	MIP
CMS3_k127_2482988_8	1306990.BARG01000134_gene10429	1.714e-84	292.0	2A201@1|root,30Q9W@2|Bacteria,2I8N1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2482988_20	290317.Cpha266_0557	3.551e-43	174.0	COG3074@1|root,COG3074@2|Bacteria,1FFHR@1090|Chlorobi	1090|Chlorobi	D	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2482988_22	883113.HMPREF9708_01265	2.219e-40	163.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,4HRIU@91061|Bacilli	91061|Bacilli	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_2482988_4	1267535.KB906767_gene447	8.479e-119	421.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_2482988_32	1485545.JQLW01000008_gene1984	1.443e-14	85.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria	1224|Proteobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS3_k127_2482988_15	1449063.JMLS01000016_gene877	2.315e-53	216.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,26RW7@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the LTA synthase family	yqgS	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2482988_24	1123020.AUIE01000008_gene3563	2.378e-35	155.0	COG0421@1|root,COG0421@2|Bacteria,1QVJA@1224|Proteobacteria,1RYYT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_2482988_29	134676.ACPL_2099	4.219e-19	100.0	COG0535@1|root,COG0535@2|Bacteria,2GTTW@201174|Actinobacteria,4DIAW@85008|Micromonosporales	201174|Actinobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_2482988_28	387631.Asulf_01575	1.664e-21	107.0	COG0535@1|root,arCOG02616@2157|Archaea,2Y0AX@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_2482988_2	521674.Plim_3913	4.171e-208	659.0	COG3119@1|root,COG3119@2|Bacteria,2IY4T@203682|Planctomycetes	203682|Planctomycetes	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CMS3_k127_2482988_21	595460.RRSWK_07231	7.52e-41	155.0	COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2482988_42	1403819.BATR01000024_gene829	1.226e-06	62.0	COG0526@1|root,COG3485@1|root,COG4932@1|root,COG0526@2|Bacteria,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K02014,ko:K03671,ko:K07152,ko:K20276	ko02024,ko04621,ko05418,map02024,map04621,map05418	-	-	-	ko00000,ko00001,ko02000,ko03029,ko03110	1.B.14	-	-	AhpC-TSA,CarboxypepD_reg,PDZ_2,Plug,Redoxin,Thioredoxin_8,TonB_dep_Rec
CMS3_k127_2482988_37	1041139.KB902735_gene5880	1.183e-09	72.0	COG4249@1|root,COG4249@2|Bacteria,1R3SZ@1224|Proteobacteria,2TVR0@28211|Alphaproteobacteria,4B96N@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Caspase domain	MA20_39250	-	-	-	-	-	-	-	-	-	-	-	Lectin_C,PG_binding_1,Peptidase_C14
CMS3_k127_2482988_5	391598.FBBAL38_09852	5.077e-115	402.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS3_k127_2482988_25	530564.Psta_2697	7.595e-33	149.0	COG1413@1|root,COG1520@1|root,COG1413@2|Bacteria,COG1520@2|Bacteria,2J3VN@203682|Planctomycetes	2|Bacteria	C	HEAT repeats	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	DNA_alkylation,HEAT_2,MFS_1,PQQ_2,cNMP_binding
CMS3_k127_2482988_18	861299.J421_1461	1.044e-45	191.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
CMS3_k127_2482988_23	234267.Acid_4815	3.454e-36	141.0	COG3682@1|root,COG3682@2|Bacteria,3Y8BB@57723|Acidobacteria	57723|Acidobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_2482988_10	933262.AXAM01000056_gene3170	4.381e-76	267.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2X5WM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_2482988_1	1047013.AQSP01000142_gene185	1.749e-301	950.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CMS3_k127_2482988_19	867845.KI911784_gene2472	5.412e-45	190.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS3_k127_2482988_14	1210884.HG799476_gene15385	1.258e-53	201.0	COG0241@1|root,COG0241@2|Bacteria,2IZYR@203682|Planctomycetes	203682|Planctomycetes	E	Polynucleotide kinase 3 phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
CMS3_k127_2482988_17	765913.ThidrDRAFT_2814	2.098e-47	186.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1R5T1@1224|Proteobacteria,1S1D6@1236|Gammaproteobacteria,1WWW7@135613|Chromatiales	135613|Chromatiales	S	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_8
CMS3_k127_2482988_7	765910.MARPU_10580	6.172e-86	299.0	COG1672@1|root,COG1672@2|Bacteria,1R5K0@1224|Proteobacteria,1RQB0@1236|Gammaproteobacteria,1WW1Y@135613|Chromatiales	135613|Chromatiales	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2482988_43	493475.GARC_3195	0.0001198	51.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2482988_6	357808.RoseRS_4100	5.941e-115	380.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,374WM@32061|Chloroflexia	2|Bacteria	M	PFAM NAD-dependent epimerase dehydratase	arnA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315	1.1.1.305,2.1.2.13,5.1.3.2	ko:K01784,ko:K10011,ko:K12449	ko00052,ko00520,ko01100,ko01503,map00052,map00520,map01100,map01503	M00361,M00362,M00632,M00721,M00761	R00291,R01384,R01386,R02984,R07658,R07660	RC00026,RC00289,RC00508,RC01575,RC01811,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iPC815.YPO2420,iSFV_1184.SFV_2325	Epimerase,Formyl_trans_C,Formyl_trans_N,GDP_Man_Dehyd
CMS3_k127_2482988_12	502025.Hoch_6088	1.793e-61	235.0	COG3172@1|root,COG3172@2|Bacteria	2|Bacteria	H	ATPase kinase involved in NAD metabolism	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
CMS3_k127_2482988_11	314230.DSM3645_04840	8.473e-63	226.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS3_k127_2482988_41	1470591.BW41_02249	2.179e-07	58.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,2U5XC@28211|Alphaproteobacteria,2K2S2@204457|Sphingomonadales	204457|Sphingomonadales	M	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
CMS3_k127_2482988_40	266117.Rxyl_0933	1.456e-07	57.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CRDV@84995|Rubrobacteria	84995|Rubrobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_2484442_1	1122939.ATUD01000004_gene3800	3.645e-136	448.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CP5Y@84995|Rubrobacteria	84995|Rubrobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS3_k127_2484442_12	382464.ABSI01000002_gene4278	1.608e-15	91.0	COG0228@1|root,COG0228@2|Bacteria,46WC2@74201|Verrucomicrobia,2IUP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S16	-	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS3_k127_2484442_10	1101189.AQUO01000001_gene3268	1.89e-26	116.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,2PUHU@265|Paracoccus	28211|Alphaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS3_k127_2484442_11	742742.HMPREF9452_01467	4.219e-24	105.0	COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS3_k127_2484442_3	991905.SL003B_0475	8.992e-108	360.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,4BPNQ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS3_k127_2484442_7	1125863.JAFN01000001_gene1724	3.57e-57	213.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS3_k127_2484442_9	452637.Oter_2288	1.573e-37	152.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS3_k127_2484442_5	797304.Natgr_0037	4.983e-79	276.0	arCOG06187@1|root,arCOG06187@2157|Archaea,2XTSP@28890|Euryarchaeota,23S9E@183963|Halobacteria	183963|Halobacteria	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2484442_2	344747.PM8797T_07137	6.483e-130	428.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,2IXF2@203682|Planctomycetes	203682|Planctomycetes	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
CMS3_k127_2484442_8	1297742.A176_05915	8.732e-38	155.0	COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,42NH0@68525|delta/epsilon subdivisions,2WM42@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate deaminase	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
CMS3_k127_2484442_0	518766.Rmar_0925	1.767e-165	576.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
CMS3_k127_2484442_4	240016.ABIZ01000001_gene5476	6.279e-94	317.0	29WV7@1|root,30IGQ@2|Bacteria,46X0W@74201|Verrucomicrobia,2IWJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_2484442_14	314230.DSM3645_25914	0.0001929	54.0	2DBPC@1|root,2ZA8K@2|Bacteria,2IX2X@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
CMS3_k127_2484442_6	1047013.AQSP01000125_gene2621	1.617e-67	241.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_2494188_5	765914.ThisiDRAFT_0469	5.878e-27	123.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1WX1W@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_2494188_4	1232447.BAHW02000049_gene3073	1.308e-71	258.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind,dTDP_sugar_isom
CMS3_k127_2494188_1	330214.NIDE3016	3.723e-103	356.0	COG1209@1|root,COG1209@2|Bacteria,3J0KX@40117|Nitrospirae	40117|Nitrospirae	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_2494188_3	344747.PM8797T_21943	5.439e-82	284.0	COG0451@1|root,COG0451@2|Bacteria,2IYGP@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS3_k127_2494188_2	309807.SRU_0634	1.812e-96	327.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1FJU8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	RmlD substrate binding domain	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_2494188_0	471854.Dfer_3000	9.068e-153	488.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,47JU8@768503|Cytophagia	976|Bacteroidetes	GM	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_2497005_1	1201288.M900_1575	0.0002835	49.0	COG3677@1|root,COG3677@2|Bacteria,1NUJD@1224|Proteobacteria,42ZJP@68525|delta/epsilon subdivisions,2MTUZ@213481|Bdellovibrionales,2WUVR@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2497005_0	134676.ACPL_6512	3.259e-25	118.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DAJ5@85008|Micromonosporales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_2497005_2	867903.ThesuDRAFT_00331	0.0002902	47.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WCU7@538999|Clostridiales incertae sedis	186801|Clostridia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_2518009_20	1123367.C666_00245	1.808e-06	58.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,2KUAM@206389|Rhodocyclales	206389|Rhodocyclales	M	Polysaccharide chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
CMS3_k127_2518009_14	983917.RGE_04240	3.122e-52	202.0	COG3307@1|root,COG3307@2|Bacteria,1PH1D@1224|Proteobacteria,2VY0G@28216|Betaproteobacteria,1KMV2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_2518009_5	187272.Mlg_0138	1.288e-153	505.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_2518009_12	1454004.AW11_02198	1.421e-60	234.0	COG0438@1|root,COG1305@1|root,COG0438@2|Bacteria,COG1305@2|Bacteria,1R564@1224|Proteobacteria,2WEG5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_2518009_11	1123060.JONP01000009_gene2156	7.714e-67	257.0	COG0438@1|root,COG0438@2|Bacteria,1PEWW@1224|Proteobacteria,2U2ZQ@28211|Alphaproteobacteria,2JQDK@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2518009_17	1232410.KI421418_gene2414	4.391e-20	106.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,43U07@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS3_k127_2518009_10	187272.Mlg_0143	3.295e-70	258.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1WWEV@135613|Chromatiales	135613|Chromatiales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
CMS3_k127_2518009_21	378806.STAUR_6496	3.519e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,1Q30N@1224|Proteobacteria,438QE@68525|delta/epsilon subdivisions,2X906@28221|Deltaproteobacteria,2YXHX@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_2518009_7	314230.DSM3645_09717	4.145e-120	416.0	COG2204@1|root,COG2204@2|Bacteria,2IYIG@203682|Planctomycetes	203682|Planctomycetes	T	CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2518009_22	85643.Tmz1t_2898	1.101e-05	58.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,2WGTY@28216|Betaproteobacteria,2KV3D@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
CMS3_k127_2518009_8	1449350.OCH239_17390	2.912e-82	284.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2V7Q4@28211|Alphaproteobacteria,4KNW6@93682|Roseivivax	28211|Alphaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2518009_15	472759.Nhal_3328	3.84e-44	186.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1WXFS@135613|Chromatiales	1236|Gammaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_2518009_9	1125863.JAFN01000001_gene619	2.29e-71	273.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,43BSH@68525|delta/epsilon subdivisions,2X73A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
CMS3_k127_2518009_23	1121930.AQXG01000001_gene1614	0.000154	50.0	29WMP@1|root,30I8G@2|Bacteria,4NYM5@976|Bacteroidetes	976|Bacteroidetes	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
CMS3_k127_2518009_18	509635.N824_27125	2.309e-16	93.0	COG0457@1|root,COG0457@2|Bacteria,4NZVB@976|Bacteroidetes,1IVUF@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_2518009_0	869213.JCM21142_93289	9.893e-207	664.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	pop	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_2518009_1	886293.Sinac_4683	1.273e-194	630.0	COG0457@1|root,COG0457@2|Bacteria	886293.Sinac_4683|-	S	peptidyl-tyrosine sulfation	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
CMS3_k127_2518009_19	502025.Hoch_0180	1.109e-13	85.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_2518009_13	886293.Sinac_3739	7.248e-58	228.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IY73@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16
CMS3_k127_2518009_16	118163.Ple7327_3262	6.85e-29	121.0	COG0607@1|root,COG0607@2|Bacteria,1G896@1117|Cyanobacteria,3VKUG@52604|Pleurocapsales	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_2518009_6	391625.PPSIR1_08117	3.9e-127	422.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,42N9T@68525|delta/epsilon subdivisions,2WPH6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
CMS3_k127_2518009_4	269084.syc2066_c	5.3e-166	537.0	COG0166@1|root,COG0166@2|Bacteria,1G0E5@1117|Cyanobacteria,1GYTZ@1129|Synechococcus	1117|Cyanobacteria	F	Belongs to the GPI family	pgi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS3_k127_2518009_2	373903.Hore_20480	1.027e-183	586.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3WB7J@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
CMS3_k127_2518009_3	460265.Mnod_1294	1.909e-181	604.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria,1JSAM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS3_k127_257470_6	1395587.P364_0118415	7.916e-11	73.0	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
CMS3_k127_257470_5	1379270.AUXF01000004_gene3199	7.568e-31	139.0	COG3342@1|root,COG3342@2|Bacteria,1ZUFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028
CMS3_k127_257470_0	1123023.JIAI01000012_gene9190	9.345e-217	719.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4DYAF@85010|Pseudonocardiales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS3_k127_257470_4	89187.ISM_16950	2.011e-54	217.0	COG0331@1|root,COG0331@2|Bacteria,1MW5Y@1224|Proteobacteria,2TT74@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-carrier-protein s-malonyltransferase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
CMS3_k127_257470_1	861299.J421_1661	5.802e-153	497.0	COG0534@1|root,COG0534@2|Bacteria,1ZUGI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS3_k127_257470_2	1254432.SCE1572_06625	1.562e-74	265.0	COG0715@1|root,COG0715@2|Bacteria,1RJQU@1224|Proteobacteria,438WV@68525|delta/epsilon subdivisions,2X42B@28221|Deltaproteobacteria,2YY20@29|Myxococcales	28221|Deltaproteobacteria	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CMS3_k127_257470_3	518766.Rmar_1178	2.135e-70	250.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1FJT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CMS3_k127_2589207_0	1121926.AXWO01000014_gene1827	8.653e-67	239.0	COG3186@1|root,COG3186@2|Bacteria,2GKCB@201174|Actinobacteria	201174|Actinobacteria	E	Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
CMS3_k127_2589207_1	349521.HCH_00812	1.859e-46	174.0	COG1515@1|root,COG1515@2|Bacteria,1MYP6@1224|Proteobacteria	1224|Proteobacteria	L	Deoxyinosine 3'endonuclease (endonuclease V)	-	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
CMS3_k127_2589207_2	382464.ABSI01000005_gene1137	2.219e-15	76.0	COG2322@1|root,COG2322@2|Bacteria,46SZT@74201|Verrucomicrobia,2IUT2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF420
CMS3_k127_2595172_3	1254432.SCE1572_22375	4.409e-36	159.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2595172_8	566461.SSFG_00091	1.915e-05	57.0	2B7WC@1|root,3213B@2|Bacteria,2H50F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2595172_5	483219.LILAB_22110	2.142e-26	125.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
CMS3_k127_2595172_2	1121468.AUBR01000032_gene1173	5.738e-45	170.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,42GV6@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS3_k127_2595172_7	717605.Theco_2052	8.328e-24	106.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,26Y58@186822|Paenibacillaceae	91061|Bacilli	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS3_k127_2595172_0	1121405.dsmv_2738	9.144e-194	645.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2MIS9@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS3_k127_2595172_4	1242864.D187_006633	4.639e-33	147.0	COG2333@1|root,COG4733@1|root,COG4932@1|root,COG2333@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.4	ko:K01179,ko:K02238,ko:K20276	ko00500,ko01100,ko02024,map00500,map01100,map02024	M00429	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.11.1,3.A.11.2	GH5,GH9	-	Lactamase_B
CMS3_k127_2595172_1	429009.Adeg_0173	1.489e-68	268.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2595172_6	1168065.DOK_00592	3.01e-25	121.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1J4IY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Type II secretory pathway, component	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS3_k127_2597076_6	661478.OP10G_0316	7.548e-61	226.0	2BZ4W@1|root,2Z7PQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2597076_17	1038859.AXAU01000018_gene6737	2.726e-09	63.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,3K0QI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
CMS3_k127_2597076_12	1122931.AUAE01000016_gene2596	2.5e-27	124.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,2FQ6R@200643|Bacteroidia,2304Q@171551|Porphyromonadaceae	976|Bacteroidetes	S	Putative esterase	xynZ	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_2597076_5	1125863.JAFN01000001_gene413	1.165e-62	224.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42URP@68525|delta/epsilon subdivisions,2WQFZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS3_k127_2597076_8	671143.DAMO_1294	3.295e-48	183.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553,ko:K14160	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS3_k127_2597076_16	247490.KSU1_D0636	8.946e-17	92.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS3_k127_2597076_18	62928.azo3569	1.744e-05	56.0	COG0515@1|root,COG0515@2|Bacteria,1RAG3@1224|Proteobacteria,2W0C1@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
CMS3_k127_2597076_9	1121346.KB899815_gene1866	2.451e-45	175.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4HEGD@91061|Bacilli,26TR8@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	mprA1	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2597076_11	1124983.PFLCHA0_c20190	6.621e-30	138.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,1RNDA@1236|Gammaproteobacteria,1YRGF@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Member of a two-component regulatory system	copS	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_2597076_10	933262.AXAM01000001_gene345	1.11e-37	155.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria,2MK0N@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_2597076_1	1123242.JH636436_gene232	2.908e-104	353.0	COG0304@1|root,COG0304@2|Bacteria,2IX8X@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_2597076_15	344747.PM8797T_12843	1.699e-18	98.0	COG0236@1|root,COG0236@2|Bacteria,2J04I@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS3_k127_2597076_14	1329516.JPST01000019_gene2728	2.288e-20	106.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_2597076_13	1379270.AUXF01000006_gene300	3.196e-27	118.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CMS3_k127_2597076_3	1230343.CANP01000023_gene1486	6.31e-73	255.0	COG0623@1|root,COG0623@2|Bacteria,1N64Z@1224|Proteobacteria,1T3N8@1236|Gammaproteobacteria,1JC7V@118969|Legionellales	118969|Legionellales	I	KR domain	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2597076_0	314230.DSM3645_05315	1.861e-268	840.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_2597076_2	313603.FB2170_09416	2.824e-86	302.0	COG0708@1|root,COG0708@2|Bacteria,4NGD8@976|Bacteroidetes,1HXFS@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
CMS3_k127_2597076_4	706587.Desti_3968	7.102e-65	245.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42V17@68525|delta/epsilon subdivisions,2WRD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_2597076_7	1123257.AUFV01000009_gene2148	1.855e-50	182.0	COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,1S69D@1236|Gammaproteobacteria,1XC2C@135614|Xanthomonadales	135614|Xanthomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_2635377_13	1144275.COCOR_02285	1.827e-44	172.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	response regulator	yehT	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS3_k127_2635377_6	357808.RoseRS_0010	2.587e-91	327.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_2635377_3	378806.STAUR_4842	4.264e-143	471.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,43BPH@68525|delta/epsilon subdivisions,2WM3W@28221|Deltaproteobacteria,2YX36@29|Myxococcales	28221|Deltaproteobacteria	H	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_2635377_14	926560.KE387023_gene2058	6.947e-38	163.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_2635377_0	886293.Sinac_0949	5.044e-244	775.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
CMS3_k127_2635377_15	913865.DOT_6294	1.903e-17	97.0	COG1723@1|root,COG1723@2|Bacteria,1TQMD@1239|Firmicutes,24CG0@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
CMS3_k127_2635377_11	1504672.669785340	6.112e-57	207.0	COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS3_k127_2635377_5	1123368.AUIS01000003_gene1812	3.573e-118	413.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,1SKSY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS3_k127_2635377_2	1121918.ARWE01000001_gene3016	3.694e-153	498.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
CMS3_k127_2635377_8	1121918.ARWE01000001_gene3015	6.757e-73	260.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,42QWA@68525|delta/epsilon subdivisions,2WMVM@28221|Deltaproteobacteria,43SVV@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
CMS3_k127_2635377_7	1122179.KB890435_gene931	3.704e-89	328.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_2635377_10	635013.TherJR_2805	4.128e-60	230.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,267E8@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
CMS3_k127_2635377_4	1047013.AQSP01000121_gene2702	6.676e-130	436.0	COG1574@1|root,COG1574@2|Bacteria,2NNTF@2323|unclassified Bacteria	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_2635377_12	867845.KI911784_gene2277	6.766e-50	198.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_2635377_16	123214.PERMA_0133	8.811e-16	79.0	COG0450@1|root,COG0450@2|Bacteria,2G3ZJ@200783|Aquificae	200783|Aquificae	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS3_k127_2635377_9	1121918.ARWE01000001_gene2503	2.996e-60	211.0	COG0450@1|root,COG0450@2|Bacteria,1MYZG@1224|Proteobacteria,42SNG@68525|delta/epsilon subdivisions,2WP3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS3_k127_2635377_1	65093.PCC7418_2271	1.083e-185	598.0	COG3044@1|root,COG3044@2|Bacteria,1G21U@1117|Cyanobacteria	1117|Cyanobacteria	S	ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
CMS3_k127_2635377_17	13735.ENSPSIP00000009621	3.83e-10	74.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,4955J@7742|Vertebrata,4CH07@8459|Testudines	33208|Metazoa	S	Inter-alpha-trypsin inhibitor heavy chain	ITIH3	GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0008150,GO:0009892,GO:0009987,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034774,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097708,GO:0098772,GO:0099503	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA
CMS3_k127_2669571_6	760192.Halhy_0626	3.431e-76	265.0	COG0654@1|root,COG0654@2|Bacteria,4NFUC@976|Bacteroidetes	976|Bacteroidetes	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS3_k127_2669571_2	1267535.KB906767_gene5138	4.465e-170	539.0	COG2813@1|root,COG2813@2|Bacteria	2|Bacteria	J	rRNA (guanine-N2-)-methyltransferase activity	-	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.304,2.1.1.333	ko:K13604,ko:K21460	ko00860,ko01110,map00860,map01110	-	R09063	RC00003,RC01662	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_12,Methyltransf_2,Methyltransf_25
CMS3_k127_2669571_10	1173263.Syn7502_03499	2.007e-09	69.0	COG1413@1|root,COG1413@2|Bacteria,1G2ZR@1117|Cyanobacteria	1117|Cyanobacteria	CT	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Vitellogenin_N
CMS3_k127_2669571_4	756272.Plabr_0423	2.363e-144	474.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2669571_9	331869.BAL199_07133	7.67e-73	253.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,4BQQW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
CMS3_k127_2669571_1	344747.PM8797T_05840	8.115e-201	646.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CMS3_k127_2669571_3	243090.RB13157	2.439e-164	569.0	COG3119@1|root,COG3119@2|Bacteria,2IYFP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_2669571_5	886293.Sinac_5379	8.473e-90	310.0	28K3C@1|root,2Z9SH@2|Bacteria,2IXIK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2669571_8	886293.Sinac_5380	6.982e-74	267.0	28PTH@1|root,2ZCER@2|Bacteria,2IZHG@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2669571_0	886293.Sinac_1376	0.0	1219.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXJQ@203682|Planctomycetes	2|Bacteria	C	polysaccharide deacetylase	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	Ceramidase_alk,Copper-bind,Cytochrom_C,DUF1080,HEAT_2,Lipase_GDSL_2,ThuA,VCBS
CMS3_k127_2669571_7	526227.Mesil_0745	7.909e-76	260.0	COG0010@1|root,COG0010@2|Bacteria,1WIEY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the arginase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_2677772_21	1449126.JQKL01000001_gene1336	7.408e-20	98.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,269AY@186813|unclassified Clostridiales	186801|Clostridia	N	OmpA family	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS3_k127_2677772_26	67315.JOBD01000050_gene4940	1.311e-06	61.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
CMS3_k127_2677772_15	575540.Isop_1579	1.478e-35	149.0	COG0030@1|root,COG0030@2|Bacteria,2IYD7@203682|Planctomycetes	203682|Planctomycetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS3_k127_2677772_11	518766.Rmar_0977	1.855e-71	265.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS3_k127_2677772_1	247490.KSU1_B0011	2.657e-179	578.0	COG0568@1|root,COG0568@2|Bacteria,2IXI3@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_2677772_27	1242969.ATCC51562_645	1.638e-05	55.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2YMAN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG1579 Zn-ribbon protein possibly nucleic acid-binding	-	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
CMS3_k127_2677772_5	316067.Geob_3729	3.229e-120	423.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
CMS3_k127_2677772_25	319003.Bra1253DRAFT_01956	9.469e-07	62.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2TU29@28211|Alphaproteobacteria,3JQN5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	HEAT repeat	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_2677772_24	1121007.AUML01000002_gene1657	8.438e-09	68.0	2DUW9@1|root,33SPC@2|Bacteria,4P1AG@976|Bacteroidetes,1I792@117743|Flavobacteriia	976|Bacteroidetes	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_3
CMS3_k127_2677772_6	391625.PPSIR1_14575	1.133e-117	388.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42RUT@68525|delta/epsilon subdivisions,2WR62@28221|Deltaproteobacteria,2Z338@29|Myxococcales	68525|delta/epsilon subdivisions	H	COG2189 Adenine specific DNA methylase Mod	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_2677772_17	502025.Hoch_4451	2.666e-29	131.0	COG0477@1|root,COG2814@2|Bacteria,1R518@1224|Proteobacteria,43B4F@68525|delta/epsilon subdivisions,2WIQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_2677772_13	1532557.JL37_22540	5.307e-65	233.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS3_k127_2677772_9	1121468.AUBR01000001_gene572	1.962e-92	316.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,25J0X@186801|Clostridia,42F6Z@68295|Thermoanaerobacterales	186801|Clostridia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS3_k127_2677772_2	309801.trd_1178	1.273e-136	460.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,27XV0@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_2677772_7	1267533.KB906734_gene4271	1.97e-105	350.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_2677772_10	443144.GM21_3731	1.258e-77	275.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,43U9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS3_k127_2677772_8	1123242.JH636434_gene3297	3.205e-99	345.0	COG1508@1|root,COG1508@2|Bacteria,2IXGU@203682|Planctomycetes	203682|Planctomycetes	K	rna polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS3_k127_2677772_22	76114.ebA6072	2.618e-15	85.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VR5K@28216|Betaproteobacteria,2KWRM@206389|Rhodocyclales	206389|Rhodocyclales	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2677772_28	1288826.MSNKSG1_05501	7.727e-05	54.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,465B4@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS3_k127_2677772_23	1307759.JOMJ01000003_gene1223	5.877e-15	83.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SZE@68525|delta/epsilon subdivisions,2X8KQ@28221|Deltaproteobacteria,2MHJ1@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS3_k127_2677772_4	247490.KSU1_B0200	1.535e-120	401.0	COG2204@1|root,COG2204@2|Bacteria,2IY95@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_2677772_19	1396418.BATQ01000009_gene3820	5.456e-28	132.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42,Glyco_hydro_42M
CMS3_k127_2677772_20	322710.Avin_23500	3.978e-26	118.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
CMS3_k127_2677772_14	589865.DaAHT2_2673	6.273e-50	191.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,2MJJQ@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS3_k127_2677772_16	344747.PM8797T_29633	2.275e-30	129.0	COG0204@1|root,COG0204@2|Bacteria,2IZVC@203682|Planctomycetes	203682|Planctomycetes	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_2677772_0	344747.PM8797T_32295	1.242e-224	712.0	COG0539@1|root,COG0539@2|Bacteria,2IXPK@203682|Planctomycetes	203682|Planctomycetes	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS3_k127_2677772_3	1121430.JMLG01000012_gene1975	5.128e-125	429.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,2601M@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS3_k127_2677772_12	382464.ABSI01000005_gene1089	1.057e-67	243.0	COG1043@1|root,COG1043@2|Bacteria,46SQN@74201|Verrucomicrobia,2IU6J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Udp N-acetylglucosamine O-acyltransferase; Domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,Hexapep
CMS3_k127_2677772_18	344747.PM8797T_17674	1.346e-28	122.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_2719687_9	1254432.SCE1572_01405	1.431e-43	166.0	COG3409@1|root,COG3409@2|Bacteria,1QEQD@1224|Proteobacteria,4319J@68525|delta/epsilon subdivisions,2WWM3@28221|Deltaproteobacteria,2Z1Q7@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2719687_7	1121430.JMLG01000001_gene2134	9.618e-65	245.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,2607V@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS3_k127_2719687_8	546414.Deide_19100	2.26e-56	220.0	COG1181@1|root,COG1181@2|Bacteria,1WIJ8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_2719687_12	208439.AJAP_26750	9.676e-35	148.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4DYXS@85010|Pseudonocardiales	201174|Actinobacteria	GK	glucokinase	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS3_k127_2719687_0	1121468.AUBR01000030_gene1226	4.313e-150	486.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,42FCV@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_2719687_14	886293.Sinac_1364	1.197e-22	102.0	COG0236@1|root,COG0236@2|Bacteria,2J0V5@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_2719687_6	742765.HMPREF9457_01933	3.176e-69	257.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27V4J@189330|Dorea	186801|Clostridia	IQ	COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_2719687_4	644966.Tmar_0947	2.122e-84	304.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,3WCVT@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_2719687_5	767817.Desgi_2802	4.659e-74	265.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS3_k127_2719687_16	985867.AEWF01000001_gene1929	8.182e-13	74.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,2UKBX@28211|Alphaproteobacteria,47FSZ@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS3_k127_2719687_1	31954.BPSP_1127	2.454e-138	456.0	COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS3_k127_2719687_3	314230.DSM3645_10162	2.373e-105	349.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS3_k127_2719687_15	1499967.BAYZ01000090_gene4950	2.45e-19	102.0	COG0392@1|root,COG0392@2|Bacteria,2NPJC@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS3_k127_2719687_10	765869.BDW_08300	1.637e-37	152.0	COG2029@1|root,COG2029@2|Bacteria,1Q1YE@1224|Proteobacteria,437KG@68525|delta/epsilon subdivisions,2MU12@213481|Bdellovibrionales,2X2UI@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
CMS3_k127_2719687_2	251221.35213389	1.498e-119	413.0	COG1087@1|root,COG1087@2|Bacteria,1G08G@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_2719687_17	1123073.KB899245_gene112	1.081e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RNVA@1236|Gammaproteobacteria,1X6C3@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5,TPR_16,TPR_19
CMS3_k127_2719687_11	156889.Mmc1_0078	7.108e-36	151.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS3_k127_2719687_18	662479.C440_14604	0.0001606	55.0	COG1413@1|root,arCOG04653@2157|Archaea,2XUXY@28890|Euryarchaeota,23SVC@183963|Halobacteria	183963|Halobacteria	C	COG1413 FOG HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_2721654_4	232348.ADXL01000042_gene1621	1.54e-48	184.0	COG0500@1|root,COG2226@2|Bacteria,1G49I@1117|Cyanobacteria,1GZF6@1129|Synechococcus	1117|Cyanobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
CMS3_k127_2721654_0	1123073.KB899242_gene1321	3.185e-130	437.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1XA6G@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2721654_2	187303.BN69_0141	5.382e-82	286.0	COG0500@1|root,COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria,37150@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_2721654_1	1173025.GEI7407_1173	2.959e-99	334.0	COG0451@1|root,COG0451@2|Bacteria,1G02N@1117|Cyanobacteria,1H7SE@1150|Oscillatoriales	1117|Cyanobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS3_k127_2721654_3	709797.CSIRO_3842	1.102e-58	214.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,1QU2F@1224|Proteobacteria,2U13V@28211|Alphaproteobacteria,3JU0P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	MQ	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS3_k127_2747294_1	313628.LNTAR_07564	4.647e-110	385.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_2747294_2	234267.Acid_4535	2.844e-13	74.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
CMS3_k127_2747294_0	1096546.WYO_3985	4.585e-268	842.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,1JU61@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
CMS3_k127_2774722_2	756272.Plabr_0707	2.32e-99	345.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,TPR_8
CMS3_k127_2774722_10	1192034.CAP_6405	1.4e-07	65.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_2774722_0	1121324.CLIT_23c00820	5.38e-107	361.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,25QDW@186804|Peptostreptococcaceae	186801|Clostridia	NU	Twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_2774722_1	760192.Halhy_3824	2.208e-104	374.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_2774722_7	216594.MMAR_0242	1.043e-32	145.0	COG0657@1|root,COG0823@1|root,COG0657@2|Bacteria,COG0823@2|Bacteria,2I40M@201174|Actinobacteria,233DD@1762|Mycobacteriaceae	201174|Actinobacteria	U	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE
CMS3_k127_2774722_9	1446473.JHWH01000001_gene1102	8.087e-10	70.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,2TTRG@28211|Alphaproteobacteria,2PUS3@265|Paracoccus	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_2774722_6	448385.sce7838	3.171e-35	155.0	COG1285@1|root,COG1285@2|Bacteria,1RAIG@1224|Proteobacteria,42T1T@68525|delta/epsilon subdivisions,2WPMM@28221|Deltaproteobacteria,2YW34@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CMS3_k127_2774722_8	177437.HRM2_21170	1.793e-21	104.0	COG5036@1|root,COG5036@2|Bacteria,1RG06@1224|Proteobacteria,42RP7@68525|delta/epsilon subdivisions,2WNHW@28221|Deltaproteobacteria,2MN1P@213118|Desulfobacterales	28221|Deltaproteobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS3_k127_2774722_4	391625.PPSIR1_08516	7.512e-52	192.0	COG2949@1|root,COG2949@2|Bacteria,1MURW@1224|Proteobacteria,4385J@68525|delta/epsilon subdivisions,2X9Y7@28221|Deltaproteobacteria,2YVVA@29|Myxococcales	28221|Deltaproteobacteria	S	DUF218 domain	-	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
CMS3_k127_2774722_3	1166018.FAES_5405	6.185e-86	312.0	COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia	976|Bacteroidetes	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_2774722_5	756272.Plabr_4793	2.388e-46	191.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPN@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrom_C,GSDH,HEAT_2
CMS3_k127_277638_5	118166.JH976537_gene2998	2.04e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
CMS3_k127_277638_1	313596.RB2501_15049	1.499e-109	370.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
CMS3_k127_277638_4	313606.M23134_06792	1.449e-16	94.0	28ZCA@1|root,2ZM41@2|Bacteria,4NMWJ@976|Bacteroidetes,47PNS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_277638_0	1047013.AQSP01000106_gene1757	5.295e-186	608.0	COG4690@1|root,COG4690@2|Bacteria,2NQBZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
CMS3_k127_277638_2	1210884.HG799467_gene13438	6.418e-80	276.0	COG1082@1|root,COG1082@2|Bacteria,2IWW9@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase domain protein TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_277638_3	1380387.JADM01000006_gene1265	1.107e-32	139.0	COG5164@1|root,COG5164@2|Bacteria,1RGAX@1224|Proteobacteria,1S5NB@1236|Gammaproteobacteria,1XPSX@135619|Oceanospirillales	135619|Oceanospirillales	K	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
CMS3_k127_2802897_14	521098.Aaci_0863	8.33e-33	134.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli	91061|Bacilli	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_2802897_15	1185876.BN8_02686	1.024e-30	127.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1,Rhodanese
CMS3_k127_2802897_8	1173028.ANKO01000127_gene4173	5.179e-80	289.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,1G3NB@1117|Cyanobacteria,1H8R0@1150|Oscillatoriales	1117|Cyanobacteria	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,NHL,Thioredoxin_8
CMS3_k127_2802897_9	1242864.D187_002708	1.321e-74	280.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS3_k127_2802897_13	1449126.JQKL01000001_gene1348	3.318e-40	162.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,26B2D@186813|unclassified Clostridiales	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
CMS3_k127_2802897_6	880073.Calab_0865	1.277e-88	302.0	COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_2802897_18	1120954.ATXE01000003_gene647	1.161e-05	58.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
CMS3_k127_2802897_11	596152.DesU5LDRAFT_2104	1.976e-56	217.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WP9Y@28221|Deltaproteobacteria,2M86H@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_2802897_2	760568.Desku_3528	1.311e-120	401.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia,263QH@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_2802897_0	1068980.ARVW01000001_gene523	1.523e-192	622.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4E0GC@85010|Pseudonocardiales	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
CMS3_k127_2802897_4	240015.ACP_1805	1.968e-117	389.0	COG0175@1|root,COG0175@2|Bacteria,3Y36I@57723|Acidobacteria,2JIQ5@204432|Acidobacteriia	204432|Acidobacteriia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS3_k127_2802897_10	485917.Phep_1253	1.858e-68	259.0	COG4409@1|root,COG4409@2|Bacteria,4P1PN@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_2802897_5	1123248.KB893381_gene986	9.74e-96	341.0	COG1073@1|root,COG1073@2|Bacteria,4NWMR@976|Bacteroidetes,1IU11@117747|Sphingobacteriia	976|Bacteroidetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DLH
CMS3_k127_2802897_21	1430440.MGMSRv2_1575	0.0007455	54.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_2802897_7	886293.Sinac_1051	6.678e-82	312.0	COG0515@1|root,COG0515@2|Bacteria,2IY6U@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_2802897_12	886293.Sinac_3694	5.249e-43	173.0	COG3568@1|root,COG3568@2|Bacteria,2IZ9W@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_2802897_1	1519464.HY22_07040	9.016e-187	602.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1FEF9@1090|Chlorobi	1090|Chlorobi	C	electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
CMS3_k127_2802897_19	547144.HydHO_0657	2.531e-05	53.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
CMS3_k127_2802897_20	639030.JHVA01000001_gene1614	0.0001444	49.0	2DQQZ@1|root,3386A@2|Bacteria,3Y8FB@57723|Acidobacteria,2JNNB@204432|Acidobacteriia	204432|Acidobacteriia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS3_k127_2802897_3	313628.LNTAR_05111	8.012e-119	390.0	COG0039@1|root,COG0039@2|Bacteria	2|Bacteria	C	L-malate dehydrogenase activity	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS3_k127_2802897_16	620914.JH621293_gene1462	1.155e-20	102.0	COG0730@1|root,COG0730@2|Bacteria,4NKPI@976|Bacteroidetes,1HZ91@117743|Flavobacteriia,2YJAE@290174|Aquimarina	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_2802897_17	1120949.KB903294_gene4611	6.282e-12	67.0	COG0642@1|root,COG2205@2|Bacteria,2GIV9@201174|Actinobacteria,4DI2W@85008|Micromonosporales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_2822227_0	380394.Lferr_1797	3.595e-15	89.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,1RR50@1236|Gammaproteobacteria,2NC0C@225057|Acidithiobacillales	225057|Acidithiobacillales	S	M61 glycyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
CMS3_k127_2822227_1	1396141.BATP01000003_gene4870	6.093e-08	66.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,PQQ_2
CMS3_k127_2825111_3	1121129.KB903364_gene2954	3.815e-06	50.0	2AHEJ@1|root,317RR@2|Bacteria,4P93N@976|Bacteroidetes,2FZC5@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2825111_2	344747.PM8797T_13570	6.485e-102	349.0	COG2262@1|root,COG2262@2|Bacteria,2IXH5@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS3_k127_2825111_0	595460.RRSWK_00598	1.464e-133	444.0	COG0029@1|root,COG0029@2|Bacteria,2IY30@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_2825111_1	237368.SCABRO_03362	1.328e-105	370.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,2IYCQ@203682|Planctomycetes	203682|Planctomycetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
CMS3_k127_2827561_9	502025.Hoch_3462	2.425e-48	197.0	COG2357@1|root,COG2357@2|Bacteria,1QYWE@1224|Proteobacteria,432GG@68525|delta/epsilon subdivisions,2WY52@28221|Deltaproteobacteria,2Z0Y8@29|Myxococcales	28221|Deltaproteobacteria	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2827561_10	314271.RB2654_10713	3.019e-47	193.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_2827561_17	1449126.JQKL01000036_gene1950	1.676e-32	141.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
CMS3_k127_2827561_24	2880.D8LR46	1.445e-07	61.0	KOG3637@1|root,KOG3637@2759|Eukaryota	2759|Eukaryota	M	integrin-mediated signaling pathway	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
CMS3_k127_2827561_0	195250.CM001776_gene625	0.0	1349.0	COG0458@1|root,COG0458@2|Bacteria,1G00J@1117|Cyanobacteria,1GYRQ@1129|Synechococcus	1117|Cyanobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS3_k127_2827561_6	1303518.CCALI_00297	6.962e-84	318.0	COG0176@1|root,COG0176@2|Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS3_k127_2827561_21	879212.DespoDRAFT_01384	5.015e-14	76.0	COG0764@1|root,COG0764@2|Bacteria,1NNU2@1224|Proteobacteria,437EX@68525|delta/epsilon subdivisions,2X2M8@28221|Deltaproteobacteria,2MP7V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
CMS3_k127_2827561_8	1005999.GLGR_0949	2.3e-64	237.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS3_k127_2827561_15	1297742.A176_07466	4.622e-36	158.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,42U1Z@68525|delta/epsilon subdivisions,2WQ05@28221|Deltaproteobacteria,2Z1RY@29|Myxococcales	28221|Deltaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_2827561_3	518766.Rmar_0345	1.252e-139	469.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM amidohydrolase	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_2827561_19	1408312.JNJS01000006_gene882	7.959e-19	95.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3NH10@46205|Pseudobutyrivibrio	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS3_k127_2827561_4	335543.Sfum_1777	2.673e-101	355.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2MRFF@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	NeuB family	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
CMS3_k127_2827561_13	1267600.JFGT01000007_gene1673	1.484e-39	159.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,3VYHC@53335|Pantoea	1236|Gammaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_1467,iECP_1309.ECP_1308	Trp_syntA
CMS3_k127_2827561_2	40571.JOEA01000008_gene2768	7.455e-140	454.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4DZ8F@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PALP
CMS3_k127_2827561_18	1449357.JQLK01000001_gene889	1.209e-22	112.0	COG0135@1|root,COG0135@2|Bacteria,1WINR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS3_k127_2827561_12	379066.GAU_1725	1.117e-39	168.0	COG0134@1|root,COG0134@2|Bacteria,1ZTMA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS3_k127_2827561_7	314278.NB231_13436	2.625e-78	285.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1WW7U@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS3_k127_2827561_11	714083.JH370377_gene763	2.709e-41	167.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4FMRP@85023|Microbacteriaceae	201174|Actinobacteria	EH	Peptidase C26	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_2827561_5	1121861.KB899911_gene1339	1.65e-86	306.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2JQBT@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS3_k127_2827561_22	635013.TherJR_1745	5.362e-12	79.0	COG4972@1|root,COG4972@2|Bacteria,1V19I@1239|Firmicutes,25DJ0@186801|Clostridia,2678V@186807|Peptococcaceae	186801|Clostridia	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS3_k127_2827561_14	1120999.JONM01000001_gene1048	2.271e-38	152.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,2KQ7E@206351|Neisseriales	206351|Neisseriales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_2827561_1	316067.Geob_2677	1.642e-157	508.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43U14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS3_k127_2827561_23	469383.Cwoe_3922	1.396e-08	67.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CR9B@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_2827561_25	640512.BC1003_4099	3.464e-05	57.0	COG0457@1|root,COG3087@1|root,COG0457@2|Bacteria,COG3087@2|Bacteria,1MVB8@1224|Proteobacteria,2VHKT@28216|Betaproteobacteria,1K2RS@119060|Burkholderiaceae	28216|Betaproteobacteria	D	cellulose synthase operon C domain protein	bscS	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_4,TPR_7,TPR_8
CMS3_k127_2827561_16	1234364.AMSF01000037_gene128	2.899e-34	145.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1X72T@135614|Xanthomonadales	135614|Xanthomonadales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_2827561_20	1121456.ATVA01000017_gene38	1.402e-17	95.0	COG0697@1|root,COG0697@2|Bacteria,1NS7A@1224|Proteobacteria,42MCJ@68525|delta/epsilon subdivisions,2WKQ4@28221|Deltaproteobacteria,2M94E@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_286018_19	1121033.AUCF01000013_gene1629	5.355e-51	183.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,2U2GS@28211|Alphaproteobacteria,2JQK5@204441|Rhodospirillales	204441|Rhodospirillales	J	Methyltransferase	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS3_k127_286018_5	391625.PPSIR1_03728	1.237e-193	610.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42Q4I@68525|delta/epsilon subdivisions,2WIX3@28221|Deltaproteobacteria,2YXDQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_286018_31	1353529.M899_1588	5.624e-12	79.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2MT0Z@213481|Bdellovibrionales,2WMRQ@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_286018_28	1280947.HY30_02065	5.342e-20	105.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2UAQW@28211|Alphaproteobacteria,43XJG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K01802,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_286018_20	344747.PM8797T_28989	4.907e-49	195.0	2DUSB@1|root,33S06@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_10	497964.CfE428DRAFT_5165	1.256e-113	375.0	COG1131@1|root,COG1131@2|Bacteria,46UCK@74201|Verrucomicrobia	74201|Verrucomicrobia	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_286018_21	497964.CfE428DRAFT_5164	1.299e-47	192.0	2EY1P@1|root,33RAP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_8	344747.PM8797T_28959	5.141e-138	473.0	COG2304@1|root,COG2304@2|Bacteria,2IXP0@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_286018_12	344747.PM8797T_28954	5.335e-95	321.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_286018_9	1123242.JH636434_gene5309	2.105e-131	465.0	COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_286018_0	344747.PM8797T_28944	5.054e-321	1014.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXKI@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA,VWA_3
CMS3_k127_286018_7	1123242.JH636434_gene5307	1.88e-148	492.0	COG3391@1|root,COG3842@1|root,COG3391@2|Bacteria,COG3842@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
CMS3_k127_286018_2	502025.Hoch_6136	6.171e-231	734.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42Q48@68525|delta/epsilon subdivisions,2X5G4@28221|Deltaproteobacteria,2YZF5@29|Myxococcales	28221|Deltaproteobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_286018_15	313596.RB2501_09100	5.09e-67	237.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,1HZVH@117743|Flavobacteriia	976|Bacteroidetes	Q	PFAM Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_286018_23	497964.CfE428DRAFT_5152	3.312e-38	161.0	2CBS1@1|root,32RTY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_34	391008.Smal_0515	3.106e-08	66.0	2DXB8@1|root,3447X@2|Bacteria,1P1UM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_13	344747.PM8797T_28929	4.849e-92	316.0	COG1840@1|root,COG1840@2|Bacteria,2IXGE@203682|Planctomycetes	203682|Planctomycetes	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
CMS3_k127_286018_16	344747.PM8797T_28924	1.901e-60	231.0	2EYED@1|root,33RNG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_4	886293.Sinac_3370	5.731e-202	671.0	COG3119@1|root,COG3119@2|Bacteria,2IXXZ@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_286018_1	1123242.JH636434_gene3172	4.153e-288	923.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_286018_17	555500.I215_05692	2.594e-60	229.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1HX7X@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_286018_36	1487953.JMKF01000009_gene6203	1.325e-05	57.0	COG0810@1|root,COG2755@1|root,COG2931@1|root,COG3055@1|root,COG0810@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,1G70I@1117|Cyanobacteria	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_286018_25	290397.Adeh_2888	5.016e-29	124.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_286018_22	875328.JDM601_3150	5.113e-41	158.0	2C945@1|root,32W5M@2|Bacteria,2I86M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	5.4.4.1	ko:K01865	ko00627,ko01120,map00627,map01120	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_286018_32	886293.Sinac_5058	1.561e-11	79.0	COG1595@1|root,COG1595@2|Bacteria,2J2PE@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
CMS3_k127_286018_35	512565.AMIS_18740	3.155e-07	64.0	COG1595@1|root,COG1595@2|Bacteria,2IKUV@201174|Actinobacteria,4DDZM@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_286018_18	1415778.JQMM01000001_gene104	2.197e-53	203.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,1RQWI@1236|Gammaproteobacteria,1J5R8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS3_k127_286018_29	1206741.BAFX01000178_gene2934	7.166e-14	81.0	2A201@1|root,30Q9W@2|Bacteria,2I8N1@201174|Actinobacteria,4G5YQ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_14	1121957.ATVL01000014_gene1459	9.469e-73	277.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_3	909663.KI867150_gene658	5.467e-202	647.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MQRF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_286018_24	342610.Patl_1101	3.969e-37	163.0	COG0367@1|root,COG0367@2|Bacteria,1NDEB@1224|Proteobacteria,1SDZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	asparagine synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_286018_26	234267.Acid_3493	9.309e-25	108.0	COG0457@1|root,COG0457@2|Bacteria,3Y75T@57723|Acidobacteria	57723|Acidobacteria	S	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase,TPR_16
CMS3_k127_286018_33	454957.IA64_00650	3.16e-10	70.0	COG5126@1|root,COG5126@2|Bacteria,1REPP@1224|Proteobacteria,1S3SP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DTZ	Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_286018_6	243090.RB728	3.746e-173	559.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
CMS3_k127_286018_11	756272.Plabr_2998	5.88e-109	373.0	COG2133@1|root,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
CMS3_k127_286018_27	234267.Acid_3493	1.907e-22	101.0	COG0457@1|root,COG0457@2|Bacteria,3Y75T@57723|Acidobacteria	57723|Acidobacteria	S	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase,TPR_16
CMS3_k127_286018_37	204669.Acid345_1676	0.0001627	48.0	2FJ4P@1|root,34AUY@2|Bacteria,3Y8PT@57723|Acidobacteria,2JNJ3@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2870403_5	530564.Psta_2085	6.886e-71	252.0	2DBNR@1|root,2ZA54@2|Bacteria,2IYX9@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS3_k127_2870403_7	448385.sce0068	2.508e-52	196.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WK2C@28221|Deltaproteobacteria,2YVZD@29|Myxococcales	28221|Deltaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS3_k127_2870403_4	1123242.JH636435_gene1551	8.299e-72	265.0	COG4242@1|root,COG4242@2|Bacteria,2IWZJ@203682|Planctomycetes	203682|Planctomycetes	PQ	Belongs to the peptidase S51 family	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
CMS3_k127_2870403_8	313589.JNB_12633	2.974e-06	56.0	COG0494@1|root,COG0494@2|Bacteria,2I3XE@201174|Actinobacteria,4FJZ2@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_2870403_0	882083.SacmaDRAFT_1933	1.745e-224	726.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4DYWI@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS3_k127_2870403_3	882083.SacmaDRAFT_1932	5.383e-93	315.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DY2C@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
CMS3_k127_2870403_6	525909.Afer_0969	1.384e-56	207.0	COG2086@1|root,COG2086@2|Bacteria,2H4H4@201174|Actinobacteria,4CNJD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_2870403_2	518766.Rmar_2656	5.735e-146	479.0	COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,1FIM8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_2870403_1	309801.trd_0150	3.844e-181	584.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS3_k127_2877072_6	237368.SCABRO_03715	1.077e-12	74.0	COG0227@1|root,COG0227@2|Bacteria,2J0SS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS3_k127_2877072_1	269796.Rru_A2936	9.061e-139	468.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,2JP9W@204441|Rhodospirillales	204441|Rhodospirillales	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	allB	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Urease_alpha
CMS3_k127_2877072_5	1279038.KB907346_gene3358	1.7e-56	220.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,2JQ56@204441|Rhodospirillales	204441|Rhodospirillales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS3_k127_2877072_7	680198.SCAB_17891	3.567e-12	79.0	COG1082@1|root,COG1082@2|Bacteria,2IH38@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2877072_3	448385.sce0867	4.194e-114	391.0	COG1099@1|root,COG1099@2|Bacteria,1MY2H@1224|Proteobacteria,43B30@68525|delta/epsilon subdivisions,2X6GS@28221|Deltaproteobacteria,2Z3B0@29|Myxococcales	28221|Deltaproteobacteria	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
CMS3_k127_2877072_2	595460.RRSWK_05376	1.097e-117	395.0	COG1409@1|root,COG1409@2|Bacteria,2J2E9@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos
CMS3_k127_2877072_0	1121382.JQKG01000009_gene768	7.717e-191	610.0	COG4108@1|root,COG4108@2|Bacteria,1WNE7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CMS3_k127_2877072_4	1121920.AUAU01000027_gene1499	3.46e-60	212.0	COG1335@1|root,COG1335@2|Bacteria,3Y5W2@57723|Acidobacteria	57723|Acidobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS3_k127_2880940_2	573063.Metin_0805	2.73e-39	156.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,23QPZ@183939|Methanococci	183939|Methanococci	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS3_k127_2880940_4	530564.Psta_2041	1.285e-29	138.0	COG1450@1|root,COG3170@1|root,COG1450@2|Bacteria,COG3170@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
CMS3_k127_2880940_7	1122137.AQXF01000001_gene2820	0.0004918	50.0	COG0848@1|root,COG0848@2|Bacteria,1RHQ3@1224|Proteobacteria	1224|Proteobacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS3_k127_2880940_3	344747.PM8797T_14087	1.179e-35	145.0	COG0811@1|root,COG0811@2|Bacteria,2IYYI@203682|Planctomycetes	203682|Planctomycetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS3_k127_2880940_1	247490.KSU1_D0069	1.769e-45	190.0	COG1450@1|root,COG1450@2|Bacteria,2IY62@203682|Planctomycetes	203682|Planctomycetes	NU	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
CMS3_k127_2880940_0	1232410.KI421424_gene1649	2.494e-53	210.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_2880940_5	582744.Msip34_2220	8.365e-11	74.0	COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,2VTTP@28216|Betaproteobacteria,2KKD2@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS3_k127_2880940_6	107635.AZUO01000002_gene3699	1.86e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,1NRW3@1224|Proteobacteria,2UQ02@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS3_k127_2882505_2	1123269.NX02_29660	0.0003204	50.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,2K57J@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_2882505_0	1089550.ATTH01000001_gene1831	5.533e-129	444.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
CMS3_k127_2882505_1	1267534.KB906757_gene1063	9.675e-39	149.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_2896312_6	269799.Gmet_2469	8.985e-05	55.0	COG1520@1|root,COG4733@1|root,COG5306@1|root,COG1520@2|Bacteria,COG4733@2|Bacteria,COG5306@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD,fn3
CMS3_k127_2896312_5	323098.Nwi_2903	1.377e-09	71.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2TRQQ@28211|Alphaproteobacteria,3JRHA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_2896312_3	886293.Sinac_5578	3.708e-24	112.0	2BACU@1|root,323T9@2|Bacteria,2J05N@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2896312_1	136993.KB900626_gene1207	3.4e-31	128.0	COG0640@1|root,COG0640@2|Bacteria,1R9XP@1224|Proteobacteria,2U5PE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Winged helix DNA-binding domain	MA20_23570	-	-	-	-	-	-	-	-	-	-	-	HTH_34
CMS3_k127_2896312_0	886293.Sinac_5576	3.811e-78	272.0	COG0761@1|root,COG0761@2|Bacteria,2IXK4@203682|Planctomycetes	203682|Planctomycetes	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,UbiA
CMS3_k127_2896312_2	765913.ThidrDRAFT_0322	7.222e-25	119.0	COG1075@1|root,COG1075@2|Bacteria,1R5PK@1224|Proteobacteria,1RP0G@1236|Gammaproteobacteria,1WX6E@135613|Chromatiales	135613|Chromatiales	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS3_k127_2896312_4	1040983.AXAE01000011_gene3071	1.777e-11	76.0	COG1807@1|root,COG1807@2|Bacteria,1RK4G@1224|Proteobacteria,2U9K9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2934033_13	398580.Dshi_0890	1.287e-67	241.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2TT7X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ornithine cyclodeaminase	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS3_k127_2934033_34	62928.azo1543	1.127e-12	79.0	COG0583@1|root,COG0583@2|Bacteria,1MXRP@1224|Proteobacteria,2VK4M@28216|Betaproteobacteria,2KVYP@206389|Rhodocyclales	206389|Rhodocyclales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS3_k127_2934033_25	313606.M23134_00707	1.451e-42	170.0	KOG3539@1|root,32TPV@2|Bacteria,4NMI6@976|Bacteroidetes,47VU6@768503|Cytophagia	976|Bacteroidetes	S	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
CMS3_k127_2934033_22	886293.Sinac_4694	1.572e-47	194.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_2934033_1	1210884.HG799464_gene10762	6.491e-188	615.0	28HSN@1|root,2Z7ZT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2934033_23	1347392.CCEZ01000074_gene1919	1.237e-46	190.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,36DF6@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
CMS3_k127_2934033_26	1123242.JH636435_gene2885	1.983e-42	179.0	COG1271@1|root,COG1271@2|Bacteria,2J2S2@203682|Planctomycetes	203682|Planctomycetes	C	oxidase subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2934033_3	502025.Hoch_5189	6.782e-175	566.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1NTJT@1224|Proteobacteria,42NK8@68525|delta/epsilon subdivisions,2WIM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
CMS3_k127_2934033_4	1517681.HW45_26270	9.618e-154	501.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1XTNI@135623|Vibrionales	135623|Vibrionales	P	COG1055 Na H antiporter NhaD and related arsenite permeases	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS3_k127_2934033_12	1123242.JH636434_gene5486	3.884e-78	276.0	COG0635@1|root,COG0635@2|Bacteria,2IWR5@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS3_k127_2934033_5	1236542.BALM01000011_gene3910	2.674e-140	467.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,2Q93R@267890|Shewanellaceae	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS3_k127_2934033_30	1191523.MROS_2381	6.325e-23	110.0	COG3288@1|root,COG3288@2|Bacteria	2|Bacteria	C	NAD(P)+ transhydrogenase (AB-specific) activity	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
CMS3_k127_2934033_9	402881.Plav_2058	2.78e-106	361.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,1JN00@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntAA	GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS3_k127_2934033_17	936574.HMPREF1508_0361	4.452e-59	215.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
CMS3_k127_2934033_24	401053.AciPR4_2986	1.625e-43	180.0	COG4365@1|root,COG4365@2|Bacteria,3Y4D6@57723|Acidobacteria,2JKER@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
CMS3_k127_2934033_28	498848.TaqDRAFT_3561	7.322e-41	171.0	COG2120@1|root,COG2120@2|Bacteria,1WIUY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS3_k127_2934033_16	521003.COLINT_03268	9.565e-60	229.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CUR3@84998|Coriobacteriia	84998|Coriobacteriia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS3_k127_2934033_10	1121930.AQXG01000011_gene1745	2.354e-104	351.0	COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia	976|Bacteroidetes	M	N-acetyl-alpha-D-glucosaminyl L-malate synthase	bshA	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_2934033_19	266940.Krad_1307	8.201e-52	207.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria	201174|Actinobacteria	E	Cysteine desulfurase	iscS	GO:0003674,GO:0003824,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0022607,GO:0031071,GO:0031163,GO:0040007,GO:0044085,GO:0044237,GO:0051186,GO:0071840	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_2934033_8	751945.Theos_0001	1.755e-109	374.0	COG0593@1|root,COG0593@2|Bacteria,1WIHX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS3_k127_2934033_18	1142394.PSMK_03840	3.759e-57	228.0	COG0592@1|root,COG0592@2|Bacteria,2IY9S@203682|Planctomycetes	203682|Planctomycetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS3_k127_2934033_37	1123508.JH636440_gene2320	9.522e-06	52.0	COG5512@1|root,COG5512@2|Bacteria,2J185@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS3_k127_2934033_0	398767.Glov_0004	7.214e-215	693.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS3_k127_2934033_32	1177179.A11A3_13205	1.735e-20	106.0	COG3008@1|root,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1XJ1N@135619|Oceanospirillales	135619|Oceanospirillales	Q	Paraquat-inducible protein B	-	-	-	-	-	-	-	-	-	-	-	-	MlaD
CMS3_k127_2934033_31	883.DvMF_0039	1.662e-22	114.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2M8FK@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM ABC transporter related	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_2934033_39	745776.DGo_CA2324	0.0005655	50.0	COG2804@1|root,COG2804@2|Bacteria,1WIW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilF	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_2934033_40	1142394.PSMK_22730	0.0007329	49.0	COG1826@1|root,COG1826@2|Bacteria,2J14F@203682|Planctomycetes	203682|Planctomycetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_2934033_2	575540.Isop_2142	9.812e-185	593.0	COG0488@1|root,COG0488@2|Bacteria,2IWXR@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS3_k127_2934033_33	344747.PM8797T_13103	3.317e-17	98.0	COG1452@1|root,COG1452@2|Bacteria,2IXFV@203682|Planctomycetes	203682|Planctomycetes	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	OstA_C
CMS3_k127_2934033_27	546271.Selsp_1898	3.404e-41	167.0	COG1778@1|root,COG1778@2|Bacteria,1V5JJ@1239|Firmicutes,4H4ID@909932|Negativicutes	909932|Negativicutes	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
CMS3_k127_2934033_11	215803.DB30_2784	3.615e-94	321.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2YV2A@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
CMS3_k127_2934033_29	237368.SCABRO_03329	1.152e-39	160.0	COG1354@1|root,COG1354@2|Bacteria,2IZIR@203682|Planctomycetes	203682|Planctomycetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS3_k127_2934033_14	1232410.KI421426_gene1407	3.6e-67	240.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43S7Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Formyl transferase, C-terminal domain	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS3_k127_2934033_21	69042.WH5701_06706	2.526e-48	191.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1G1K0@1117|Cyanobacteria,1GYZM@1129|Synechococcus	1117|Cyanobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
CMS3_k127_2934033_15	861299.J421_5641	4.058e-66	236.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	AP_endonuc_2
CMS3_k127_2934033_6	1379698.RBG1_1C00001G0513	1.111e-133	441.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS3_k127_2934033_7	391625.PPSIR1_21799	2.976e-110	374.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WNH1@28221|Deltaproteobacteria,2Z329@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS3_k127_2934033_36	1203622.HMPREF1290_01449	2.157e-07	63.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,22JRF@1653|Corynebacteriaceae	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS3_k127_2934033_35	266117.Rxyl_1135	1.005e-10	75.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_2934033_38	324057.Pjdr2_1167	1.707e-05	58.0	COG1470@1|root,COG1621@1|root,COG3408@1|root,COG5434@1|root,COG1470@2|Bacteria,COG1621@2|Bacteria,COG3408@2|Bacteria,COG5434@2|Bacteria,1UI0G@1239|Firmicutes,4IT73@91061|Bacilli,2778S@186822|Paenibacillaceae	91061|Bacilli	GM	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM9_1,Cadherin-like,SLH
CMS3_k127_2934033_20	316274.Haur_4056	1.944e-48	196.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,2G9GE@200795|Chloroflexi,3774I@32061|Chloroflexia	32061|Chloroflexia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2938467_1	518766.Rmar_0906	7.303e-183	587.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes	976|Bacteroidetes	J	Peptidase m28	PGCP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_2938467_0	243231.GSU3423	6.115e-214	685.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,43UFT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS3_k127_2956613_3	1142394.PSMK_08370	1.318e-99	340.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_2956613_5	471853.Bcav_1003	1.219e-32	139.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria	201174|Actinobacteria	DM	biosynthesis protein	wcoI	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
CMS3_k127_2956613_0	997346.HMPREF9374_3243	1.783e-229	722.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,27BE2@186824|Thermoactinomycetaceae	91061|Bacilli	E	Urocanase C-terminal domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
CMS3_k127_2956613_1	684949.ATTJ01000001_gene2444	6.605e-148	484.0	COG2986@1|root,COG2986@2|Bacteria,1WISU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CMS3_k127_2956613_4	247490.KSU1_B0552	3.193e-53	214.0	COG4775@1|root,COG4775@2|Bacteria,2IWWA@203682|Planctomycetes	203682|Planctomycetes	M	Outer membrane protein assembly complex, YaeT protein	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_2956613_2	247490.KSU1_B0551	3.751e-127	422.0	COG0305@1|root,COG0305@2|Bacteria,2IXJT@203682|Planctomycetes	203682|Planctomycetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS3_k127_2956613_6	1232437.KL662005_gene4299	2.074e-05	52.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MI69@213118|Desulfobacterales	28221|Deltaproteobacteria	D	DNA segregation ATPase, FtsK SpoIIIE family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS3_k127_2968949_0	1034345.CAEM01000053_gene295	0.0001	54.0	COG5495@1|root,COG5495@2|Bacteria,2I2F6@201174|Actinobacteria,4CW2V@84998|Coriobacteriia	84998|Coriobacteriia	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored
CMS3_k127_2973289_4	314230.DSM3645_11597	1.563e-18	98.0	COG0486@1|root,COG0486@2|Bacteria,2IZ5M@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin- like GTPase superfamily. TrmE GTPase family	-	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,TrmE_N
CMS3_k127_2973289_1	319795.Dgeo_0256	7.509e-90	321.0	COG2805@1|root,COG2805@2|Bacteria,1WI5S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Tfp pilus assembly protein pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_2973289_0	429009.Adeg_0185	4.963e-109	362.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,42F3Z@68295|Thermoanaerobacterales	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
CMS3_k127_2973289_2	1142394.PSMK_11760	1.487e-27	113.0	COG0211@1|root,COG0211@2|Bacteria,2J04T@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS3_k127_2973289_3	314230.DSM3645_09107	5.727e-20	93.0	COG0261@1|root,COG0261@2|Bacteria,2J0XA@203682|Planctomycetes	203682|Planctomycetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS3_k127_2974122_0	1042377.AFPJ01000055_gene963	6.694e-70	264.0	28MA5@1|root,2ZANY@2|Bacteria,1RIQ2@1224|Proteobacteria,1S60Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2974122_2	551275.KB899548_gene215	6.455e-25	122.0	2ARAV@1|root,2ZES8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2974122_1	1128421.JAGA01000001_gene2321	3.251e-30	136.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_2988116_27	1158756.AQXQ01000009_gene1006	3.412e-34	148.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1SZ84@1236|Gammaproteobacteria,1WXUW@135613|Chromatiales	135613|Chromatiales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_2988116_10	880071.Fleli_3724	2.245e-100	349.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,47KI1@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS3_k127_2988116_14	1382304.JNIL01000001_gene1202	9.585e-89	305.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,279JT@186823|Alicyclobacillaceae	91061|Bacilli	CH	D-isomer specific 2-hydroxyacid dehydrogenase	ghrB_1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_2988116_34	234267.Acid_5444	3.096e-07	64.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS3_k127_2988116_7	96561.Dole_2246	2.05e-106	376.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,2MIPM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_8,PAS_9,Response_reg
CMS3_k127_2988116_32	1121920.AUAU01000006_gene297	1.513e-14	84.0	COG3794@1|root,COG3794@2|Bacteria,3Y4UD@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2988116_24	1295642.H839_07284	2.453e-46	193.0	COG0584@1|root,COG3540@1|root,COG0584@2|Bacteria,COG3540@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,1WG8A@129337|Geobacillus	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,PhoD,PhoD_N
CMS3_k127_2988116_18	1108045.GORHZ_073_00030	8.62e-71	271.0	COG0457@1|root,COG2885@1|root,COG2931@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,COG2931@2|Bacteria,2IBAR@201174|Actinobacteria	201174|Actinobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2988116_29	886293.Sinac_2657	4.984e-32	144.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
CMS3_k127_2988116_30	1121272.KB903251_gene666	2.205e-16	94.0	COG1404@1|root,COG2866@1|root,COG1404@2|Bacteria,COG2866@2|Bacteria,2GJYH@201174|Actinobacteria,4DBUI@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
CMS3_k127_2988116_17	880073.Calab_1716	7.301e-73	275.0	COG0737@1|root,COG2866@1|root,COG4412@1|root,COG0737@2|Bacteria,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	cpt	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14,Peptidase_M6,SBP_bac_8,SLH
CMS3_k127_2988116_0	1125973.JNLC01000011_gene480	0.0	1071.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	Sardh	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CMS3_k127_2988116_33	682795.AciX8_1655	4.267e-12	76.0	COG0560@1|root,COG0560@2|Bacteria,3Y3RE@57723|Acidobacteria,2JI0Y@204432|Acidobacteriia	204432|Acidobacteriia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS3_k127_2988116_2	502025.Hoch_4025	7.124e-154	502.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA1@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS3_k127_2988116_19	555779.Dthio_PD1703	2.716e-66	229.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria,2MGS7@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_2988116_15	555779.Dthio_PD1703	1.495e-87	306.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria,2MGS7@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_2988116_13	1121413.JMKT01000009_gene2072	6.019e-91	305.0	COG0425@1|root,COG1765@1|root,COG0425@2|Bacteria,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	2.1.1.14	ko:K00549,ko:K04085	ko00270,ko00450,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map01100,map01110,map01230,map04122	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Meth_synt_2,OsmC,SnoaL_2,TusA
CMS3_k127_2988116_22	1121413.JMKT01000009_gene2073	9.719e-56	196.0	COG2044@1|root,COG2044@2|Bacteria,1RIFN@1224|Proteobacteria,42UMB@68525|delta/epsilon subdivisions,2WQMD@28221|Deltaproteobacteria,2MD9S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM DsrE family protein	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS3_k127_2988116_31	1123507.ATVQ01000003_gene618	1.079e-14	78.0	2BMJ7@1|root,32G45@2|Bacteria,2H1DR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
CMS3_k127_2988116_4	761193.Runsl_0720	9.471e-111	372.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47Q3U@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS3_k127_2988116_1	761193.Runsl_1927	3.734e-200	645.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,47M1X@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_2988116_21	886293.Sinac_7014	5.242e-60	220.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	2.7.1.89	ko:K07251	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	APH,Choline_kinase
CMS3_k127_2988116_25	502558.EGYY_28400	7.251e-45	180.0	COG1055@1|root,COG1055@2|Bacteria,2GMQJ@201174|Actinobacteria,4CUV8@84998|Coriobacteriia	84998|Coriobacteriia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS3_k127_2988116_23	1205680.CAKO01000002_gene2945	8.21e-55	220.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2JPZ6@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	2.4.1.83,2.4.2.53	ko:K00721,ko:K10012	ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503	M00721,M00761	R01009,R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
CMS3_k127_2988116_16	1403819.BATR01000031_gene991	2.611e-80	287.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_2988116_26	1121035.AUCH01000013_gene3143	5.698e-39	169.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,2KUB6@206389|Rhodocyclales	206389|Rhodocyclales	ET	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_2988116_9	313603.FB2170_10111	1.378e-101	369.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
CMS3_k127_2988116_3	313628.LNTAR_16998	1.923e-152	499.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
CMS3_k127_2988116_11	314230.DSM3645_25427	5.406e-98	341.0	COG0657@1|root,COG0657@2|Bacteria,2IY98@203682|Planctomycetes	203682|Planctomycetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CMS3_k127_2988116_28	706587.Desti_1503	7.579e-34	148.0	COG0535@1|root,COG0535@2|Bacteria,1N2I6@1224|Proteobacteria,42P9K@68525|delta/epsilon subdivisions,2WQ2D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_2988116_20	880072.Desac_2636	9.577e-63	242.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_2988116_5	357804.Ping_0836	1.667e-110	380.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,2QHI3@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS_4,PAS_8
CMS3_k127_2988116_6	1395587.P364_0132850	1.378e-106	356.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli	91061|Bacilli	P	phosphate	pstS	GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_2988116_8	344747.PM8797T_06617	1.571e-103	351.0	COG0573@1|root,COG0573@2|Bacteria,2IZ0E@203682|Planctomycetes	203682|Planctomycetes	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS3_k127_2988116_12	857293.CAAU_0183	3.197e-92	320.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,36DCX@31979|Clostridiaceae	186801|Clostridia	P	Phosphate transport system permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
CMS3_k127_3000453_17	765420.OSCT_0941	4.522e-42	179.0	COG4279@1|root,COG4279@2|Bacteria,2G7AI@200795|Chloroflexi	200795|Chloroflexi	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS3_k127_3000453_1	483219.LILAB_10055	2.522e-214	708.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WM1R@28221|Deltaproteobacteria,2YUN5@29|Myxococcales	28221|Deltaproteobacteria	L	Helicase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
CMS3_k127_3000453_11	235909.GK1588	2.82e-84	289.0	COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli,1WG5D@129337|Geobacillus	91061|Bacilli	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
CMS3_k127_3000453_29	448385.sce3216	5.085e-07	63.0	29ZE1@1|root,30MD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3000453_4	1121920.AUAU01000007_gene543	2.791e-152	491.0	COG0604@1|root,COG0604@2|Bacteria,3Y4X4@57723|Acidobacteria	57723|Acidobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3000453_9	1121920.AUAU01000023_gene2392	1.379e-90	312.0	2CCCK@1|root,2Z7UH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_3000453_22	743719.PaelaDRAFT_4122	1.916e-23	108.0	COG1309@1|root,COG1309@2|Bacteria,1VE3Q@1239|Firmicutes,4HMDT@91061|Bacilli,26QH4@186822|Paenibacillaceae	91061|Bacilli	K	TetR family transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
CMS3_k127_3000453_8	530564.Psta_2519	1.161e-99	357.0	COG3345@1|root,COG3345@2|Bacteria,2J1YM@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_3000453_27	926550.CLDAP_26360	1.464e-12	81.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3000453_0	309807.SRU_2034	1.157e-253	801.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
CMS3_k127_3000453_26	9707.XP_004411520.1	2.275e-13	84.0	COG2304@1|root,2RXR2@2759|Eukaryota,39SWZ@33154|Opisthokonta,3BAZH@33208|Metazoa,3D3FX@33213|Bilateria,487Y2@7711|Chordata,490XS@7742|Vertebrata,3J6GI@40674|Mammalia,3EJ98@33554|Carnivora	33208|Metazoa	W	Inter-alpha-trypsin inhibitor heavy chain	ITIH1	GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0043167,GO:0043169,GO:0046872	-	ko:K19014	-	-	-	-	ko00000,ko00536	-	-	-	ITI_HC_C,VIT,VWA
CMS3_k127_3000453_2	1196323.ALKF01000192_gene3128	6.005e-186	594.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,4ICB3@91061|Bacilli,2722P@186822|Paenibacillaceae	91061|Bacilli	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CMS3_k127_3000453_13	180281.CPCC7001_1466	2.059e-63	244.0	COG5031@1|root,COG5031@2|Bacteria,1G5JB@1117|Cyanobacteria,22TTH@167375|Cyanobium	1117|Cyanobacteria	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	-	-	-	-	-	-	-	-	-	Coq4
CMS3_k127_3000453_3	452637.Oter_0373	1.827e-173	564.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA3	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS3_k127_3000453_30	518766.Rmar_2225	3.416e-06	57.0	COG5660@1|root,COG5660@2|Bacteria,4PF9I@976|Bacteroidetes,1FKBP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_3000453_15	314230.DSM3645_06149	2.955e-48	180.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3000453_28	1300345.LF41_1844	2.056e-10	72.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,1S96R@1236|Gammaproteobacteria,1X8YE@135614|Xanthomonadales	135614|Xanthomonadales	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3000453_24	1121106.JQKB01000007_gene1028	2.234e-22	108.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria,2JXBK@204441|Rhodospirillales	204441|Rhodospirillales	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3000453_16	91464.S7335_4854	4.091e-48	188.0	COG0697@1|root,COG0697@2|Bacteria,1G4GW@1117|Cyanobacteria,1H1EW@1129|Synechococcus	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_3000453_21	411684.HPDFL43_02200	2.624e-24	114.0	KOG3539@1|root,32TPV@2|Bacteria,1N2ES@1224|Proteobacteria	1224|Proteobacteria	M	Spondin_N	-	-	-	-	-	-	-	-	-	-	-	-	Spond_N
CMS3_k127_3000453_7	1487953.JMKF01000028_gene1341	6.235e-115	381.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1H99G@1150|Oscillatoriales	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_3000453_20	886293.Sinac_3442	1.357e-24	122.0	COG0526@1|root,COG1470@1|root,COG1595@1|root,COG0526@2|Bacteria,COG1470@2|Bacteria,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	AhpC-TSA,DUF4384,NPCBM_assoc,PEGA,Sigma70_r2,Sigma70_r4_2,Thioredoxin_8
CMS3_k127_3000453_14	886293.Sinac_5471	1.458e-52	210.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
CMS3_k127_3000453_25	1123072.AUDH01000001_gene3003	2.891e-21	106.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,2JS8K@204441|Rhodospirillales	204441|Rhodospirillales	Q	MlaD protein	-	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_3000453_12	1267533.KB906734_gene4165	1.131e-66	250.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria,2JHWI@204432|Acidobacteriia	2|Bacteria	Q	pfam abc	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS3_k127_3000453_10	1192034.CAP_6879	3.737e-87	301.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,2Z0CT@29|Myxococcales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
CMS3_k127_3000453_18	391625.PPSIR1_27463	4.739e-26	123.0	COG1633@1|root,COG1633@2|Bacteria,1QA00@1224|Proteobacteria,434PZ@68525|delta/epsilon subdivisions,2X8YV@28221|Deltaproteobacteria,2Z13N@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3000453_5	1380394.JADL01000026_gene4735	3.015e-146	475.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2JQDT@204441|Rhodospirillales	204441|Rhodospirillales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS3_k127_3000453_6	1123257.AUFV01000021_gene2018	1.059e-121	401.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_3000453_19	497964.CfE428DRAFT_3955	6.131e-25	107.0	2EH6J@1|root,33AYF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3000453_23	671143.DAMO_2125	2.306e-23	105.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_3007441_0	323261.Noc_1762	3.527e-07	62.0	COG5276@1|root,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria,1T2RF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP
CMS3_k127_3009454_2	472759.Nhal_3600	1.016e-111	411.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1WXKG@135613|Chromatiales	135613|Chromatiales	DM	mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel,MscS_TM,MscS_porin
CMS3_k127_3009454_9	1304888.ATWF01000001_gene2190	7.797e-19	94.0	COG0589@1|root,COG0589@2|Bacteria,2GFI3@200930|Deferribacteres	200930|Deferribacteres	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_3009454_5	1142394.PSMK_27550	1.049e-82	285.0	COG0530@1|root,COG0530@2|Bacteria,2J32A@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_3009454_3	237368.SCABRO_03321	2.07e-111	373.0	COG1253@1|root,COG1253@2|Bacteria	2|Bacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
CMS3_k127_3009454_4	1123072.AUDH01000001_gene3133	1.839e-84	295.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TTCJ@28211|Alphaproteobacteria,2JV7K@204441|Rhodospirillales	204441|Rhodospirillales	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3009454_7	379066.GAU_3517	1.259e-55	198.0	COG0783@1|root,COG0783@2|Bacteria	2|Bacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS3_k127_3009454_6	1249627.D779_2281	1.986e-70	246.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,1RYT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	N-formylglutamate amidohydrolase	hutG	-	3.5.1.68,3.5.3.8	ko:K01458,ko:K01479	ko00340,ko00630,ko01100,map00340,map00630,map01100	M00045	R00525,R02285	RC00165,RC00221,RC00323,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
CMS3_k127_3009454_1	1249627.D779_2280	1.806e-186	629.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
CMS3_k127_3009454_0	1249627.D779_2279	3.236e-278	872.0	COG0624@1|root,COG1181@1|root,COG0624@2|Bacteria,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1WWYB@135613|Chromatiales	1236|Gammaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_3009454_8	224911.27356516	3.31e-32	138.0	COG1305@1|root,COG1305@2|Bacteria,1PMTX@1224|Proteobacteria,2V0E7@28211|Alphaproteobacteria,3K3MW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut
CMS3_k127_3034282_0	1216932.CM240_2170	1.053e-76	279.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,36DT0@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
CMS3_k127_3034282_1	365528.KB891137_gene379	3.987e-05	55.0	COG1361@1|root,COG4625@1|root,COG4719@1|root,COG1361@2|Bacteria,COG4625@2|Bacteria,COG4719@2|Bacteria,2I8F1@201174|Actinobacteria	201174|Actinobacteria	M	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
CMS3_k127_3050268_0	768671.ThimaDRAFT_0215	1.576e-132	439.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
CMS3_k127_3050268_2	8932.XP_005513393.1	3.965e-21	109.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,483KS@7711|Chordata,48WWG@7742|Vertebrata,4GQX0@8782|Aves	33208|Metazoa	S	Transmembrane and TPR repeat-containing protein 4	TMTC4	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_3050268_3	1304885.AUEY01000065_gene1294	8.557e-19	101.0	COG1520@1|root,COG3979@1|root,COG4733@1|root,COG1520@2|Bacteria,COG3979@2|Bacteria,COG4733@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria,2MNQH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_3050268_4	1408224.SAMCCGM7_c4299	2.055e-05	55.0	COG1595@1|root,COG1595@2|Bacteria,1RKMN@1224|Proteobacteria,2U9GS@28211|Alphaproteobacteria,4BDTH@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3050268_1	1267533.KB906734_gene4055	1.143e-38	152.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_3213127_8	1123242.JH636434_gene4957	9.852e-92	311.0	COG1216@1|root,COG1216@2|Bacteria,2IYBZ@203682|Planctomycetes	203682|Planctomycetes	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3213127_16	269799.Gmet_0588	2.998e-41	172.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
CMS3_k127_3213127_17	1131269.AQVV01000008_gene943	5.172e-38	158.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
CMS3_k127_3213127_36	28444.JODQ01000010_gene3249	2.191e-07	64.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4EHT1@85012|Streptosporangiales	201174|Actinobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS3_k127_3213127_23	926554.KI912668_gene5114	3.965e-25	121.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS3_k127_3213127_27	1123277.KB893239_gene1178	3.995e-16	91.0	COG0515@1|root,COG0515@2|Bacteria,4NIMA@976|Bacteroidetes,47MCM@768503|Cytophagia	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08838,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko04131	-	-	-	MORN,Pkinase
CMS3_k127_3213127_31	1121106.JQKB01000032_gene4403	1.615e-10	73.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,2U93S@28211|Alphaproteobacteria,2JSGB@204441|Rhodospirillales	204441|Rhodospirillales	M	COG1596 Periplasmic protein involved in polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS3_k127_3213127_7	196490.AUEZ01000001_gene7414	4.651e-95	321.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2TRZB@28211|Alphaproteobacteria,3K08D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_transf_7C,Glycos_transf_2
CMS3_k127_3213127_9	639030.JHVA01000001_gene2812	2.516e-90	305.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
CMS3_k127_3213127_20	1173020.Cha6605_5725	8.502e-28	126.0	COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3213127_26	1158294.JOMI01000003_gene2066	5.1e-18	96.0	COG0535@1|root,COG0535@2|Bacteria,4PA9R@976|Bacteroidetes,2FWDR@200643|Bacteroidia	976|Bacteroidetes	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_3213127_5	765912.Thimo_3077	3.855e-109	372.0	COG2327@1|root,COG2327@2|Bacteria,1MXWP@1224|Proteobacteria,1T8HH@1236|Gammaproteobacteria,1X1U8@135613|Chromatiales	135613|Chromatiales	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
CMS3_k127_3213127_19	1396141.BATP01000037_gene3528	7.533e-30	138.0	COG5017@1|root,COG5017@2|Bacteria,46XGH@74201|Verrucomicrobia,2IVUQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
CMS3_k127_3213127_15	1354722.JQLS01000004_gene4055	2.544e-41	158.0	COG0707@1|root,COG0707@2|Bacteria,1RJH9@1224|Proteobacteria,2UCZ1@28211|Alphaproteobacteria,46REU@74030|Roseovarius	28211|Alphaproteobacteria	M	Oligosaccharide biosynthesis protein Alg14 like	pssD	-	-	-	-	-	-	-	-	-	-	-	Alg14
CMS3_k127_3213127_3	765912.Thimo_3072	1.92e-132	439.0	COG1035@1|root,COG1035@2|Bacteria,1R45V@1224|Proteobacteria,1RSF5@1236|Gammaproteobacteria,1X1N9@135613|Chromatiales	135613|Chromatiales	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	FrhB_FdhB_C,FrhB_FdhB_N
CMS3_k127_3213127_22	1192034.CAP_3244	7.92e-27	115.0	COG3682@1|root,COG3682@2|Bacteria,1RKDI@1224|Proteobacteria,4383A@68525|delta/epsilon subdivisions,2X3DA@28221|Deltaproteobacteria,2YVI8@29|Myxococcales	28221|Deltaproteobacteria	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_3213127_21	379066.GAU_0801	7.043e-27	125.0	COG1413@1|root,COG4219@1|root,COG1413@2|Bacteria,COG4219@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Peptidase_M56
CMS3_k127_3213127_11	1218074.BAXZ01000001_gene144	4.134e-66	237.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_3213127_28	521674.Plim_0454	1.847e-15	85.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	1.3.7.14,1.3.7.15	ko:K03088,ko:K11333	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000,ko03021	-	-	-	Fer4_NifH,Glyco_hydro_cc,Laminin_G_3,Sigma70_r2,Sigma70_r4_2
CMS3_k127_3213127_25	1128421.JAGA01000002_gene78	1.074e-22	113.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
CMS3_k127_3213127_13	397291.C804_00534	3.115e-60	219.0	COG0223@1|root,COG0223@2|Bacteria	2|Bacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	GO:0003674,GO:0003824,GO:0004479,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044419,GO:0046483,GO:0046983,GO:0051704,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.2,2.1.2.9	ko:K00604,ko:K11175	ko00230,ko00670,ko00970,ko01100,ko01110,ko01130,map00230,map00670,map00970,map01100,map01110,map01130	M00048	R03940,R04325,R04326	RC00026,RC00165,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Formyl_trans_C,Formyl_trans_N,PP-binding
CMS3_k127_3213127_6	1163389.OOM_0820	2.529e-103	358.0	COG1621@1|root,COG1621@2|Bacteria,1N5AZ@1224|Proteobacteria,1T04N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3213127_14	344747.PM8797T_27612	1.328e-49	189.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CMS3_k127_3213127_2	1380394.JADL01000011_gene4088	6.081e-150	502.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,2JR5R@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	-	-	6.3.2.14	ko:K02364	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,PP-binding,Thioesterase,ketoacyl-synt
CMS3_k127_3213127_12	1187848.AJYQ01000004_gene177	4.998e-65	231.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1XY81@135623|Vibrionales	135623|Vibrionales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_3213127_37	1321782.HMPREF1986_02105	1.179e-05	58.0	COG0236@1|root,COG0236@2|Bacteria,1VGGM@1239|Firmicutes,24Q2V@186801|Clostridia,2PTSV@265975|Oribacterium	186801|Clostridia	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_3213127_0	269799.Gmet_2332	7.802e-171	547.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42N6P@68525|delta/epsilon subdivisions,2WJVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_3213127_10	1047013.AQSP01000112_gene393	8.672e-83	293.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3,STAS
CMS3_k127_3213127_4	446462.Amir_1753	7.238e-123	406.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2I5Z7@201174|Actinobacteria,4E2FS@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	2.4.1.289	ko:K16870	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_trans_2_3,Glycos_transf_2
CMS3_k127_3213127_30	1458357.BG58_31620	3.276e-11	72.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2VN0C@28216|Betaproteobacteria,1JZZE@119060|Burkholderiaceae	28216|Betaproteobacteria	D	PFAM lipopolysaccharide biosynthesis	epsG	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CBP_BcsQ,CbiA,GNVR,ParA,Wzz
CMS3_k127_3213127_34	1502852.FG94_04460	5.72e-08	67.0	COG3206@1|root,COG3206@2|Bacteria,1RK0N@1224|Proteobacteria,2VHPS@28216|Betaproteobacteria,47233@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Chain length determinant protein	epsF	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
CMS3_k127_3213127_1	595460.RRSWK_03836	3.528e-150	488.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3213127_33	57918.XP_004302549.1	6.896e-09	69.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37QA6@33090|Viridiplantae,3G7J7@35493|Streptophyta,4JFQ9@91835|fabids	35493|Streptophyta	S	F-box LRR-repeat protein	-	-	-	ko:K10268	-	-	-	-	ko00000,ko04121	-	-	-	LRR_6
CMS3_k127_3213127_24	530564.Psta_3753	3.9e-23	109.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3213127_35	1196323.ALKF01000186_gene5706	9.129e-08	55.0	COG0695@1|root,COG0695@2|Bacteria,1VGHM@1239|Firmicutes,4HQ0H@91061|Bacilli,26YY5@186822|Paenibacillaceae	91061|Bacilli	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS3_k127_3213127_32	875328.JDM601_1766	5.418e-10	73.0	COG1595@1|root,COG1595@2|Bacteria,2GM3E@201174|Actinobacteria,232BX@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigL	GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
CMS3_k127_3213127_38	448385.sce1844	5.85e-05	57.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_3221638_0	756272.Plabr_4315	2.054e-257	825.0	COG2010@1|root,COG2010@2|Bacteria,2IX5D@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_3221638_1	314230.DSM3645_24600	2.691e-183	627.0	COG4102@1|root,COG4102@2|Bacteria,2IX70@203682|Planctomycetes	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_3221638_7	1353529.M899_1872	4.244e-08	61.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2MT9B@213481|Bdellovibrionales,2WT4M@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	cyclic nucleotide-binding	-	-	-	ko:K03321,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko02000,ko03000	2.A.53.3	-	-	FliG_C,cNMP_binding
CMS3_k127_3221638_2	886293.Sinac_5718	3.403e-147	484.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CMS3_k127_3221638_6	1232410.KI421415_gene3013	1.778e-16	94.0	COG3063@1|root,COG3063@2|Bacteria,1RAKA@1224|Proteobacteria,42RDJ@68525|delta/epsilon subdivisions,2WMUU@28221|Deltaproteobacteria,43SG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS3_k127_3221638_4	240016.ABIZ01000001_gene3262	9.954e-75	283.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	pepX2	-	3.4.14.5	ko:K01278,ko:K06889	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_3221638_3	616991.JPOO01000003_gene29	3.891e-89	328.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_3221638_5	756272.Plabr_2893	1.972e-55	197.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
CMS3_k127_3241870_1	237368.SCABRO_02683	6.055e-08	64.0	COG1596@1|root,COG1596@2|Bacteria,2J059@203682|Planctomycetes	203682|Planctomycetes	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS3_k127_3241870_0	35841.BT1A1_3283	2.639e-123	400.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1ZBFX@1386|Bacillus	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS3_k127_3252014_1	1090319.KE386571_gene1612	0.0003797	46.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,2K0YQ@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_3252014_0	1192034.CAP_5222	3.22e-38	161.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,43ARK@68525|delta/epsilon subdivisions,2X65I@28221|Deltaproteobacteria,2YWWX@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_3272883_3	1089551.KE386572_gene3637	1.833e-47	171.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,4BRH2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EG	Dehydratase family	-	-	4.2.1.25	ko:K13875	ko00053,ko01100,map00053,map01100	-	R02522	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
CMS3_k127_3272883_1	324602.Caur_0649	8.017e-124	423.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_3272883_0	1123508.JH636445_gene6533	1.183e-224	738.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2J2ME@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_3272883_2	211114.JOEF01000006_gene2489	3.725e-70	245.0	COG2320@1|root,COG2320@2|Bacteria,2ICDV@201174|Actinobacteria,4E3U7@85010|Pseudonocardiales	201174|Actinobacteria	Q	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB,Methyltransf_11
CMS3_k127_3272883_5	1242864.D187_003613	1.282e-17	91.0	COG0625@1|root,COG0625@2|Bacteria,1NW7E@1224|Proteobacteria,437U6@68525|delta/epsilon subdivisions,2X33T@28221|Deltaproteobacteria,2YU3E@29|Myxococcales	28221|Deltaproteobacteria	O	glutathione transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3318150_15	1122165.AUHS01000046_gene2436	5.358e-07	58.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3318150_12	877411.JMMA01000002_gene755	1.641e-27	117.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS3_k127_3318150_6	404589.Anae109_0165	2e-74	284.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2YUTZ@29|Myxococcales	28221|Deltaproteobacteria	M	Mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS3_k127_3318150_13	237368.SCABRO_00201	3.666e-13	84.0	COG3164@1|root,COG3164@2|Bacteria	2|Bacteria	D	Protein of unknown function	MA20_30770	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA_1,AsmA_2,DUF3971
CMS3_k127_3318150_16	309800.C498_19234	3.86e-06	51.0	arCOG02989@1|root,arCOG02989@2157|Archaea,2Y00B@28890|Euryarchaeota,23XHN@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1931
CMS3_k127_3318150_18	1123226.KB899279_gene2431	0.0006443	53.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,26REA@186822|Paenibacillaceae	91061|Bacilli	O	Peptidase, M22	yeaZ	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_3318150_4	1267534.KB906759_gene1844	2.536e-101	360.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_3318150_9	247490.KSU1_C1010	5.593e-58	210.0	COG1624@1|root,COG1624@2|Bacteria,2IZSP@203682|Planctomycetes	203682|Planctomycetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
CMS3_k127_3318150_8	454957.IA64_11265	2.033e-62	231.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1X3ZA@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS3_k127_3318150_1	1156937.MFUM_580005	1.802e-176	580.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,37GBM@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
CMS3_k127_3318150_17	247490.KSU1_C1008	0.0002156	53.0	COG2980@1|root,COG2980@2|Bacteria,2J0MT@203682|Planctomycetes	203682|Planctomycetes	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
CMS3_k127_3318150_14	1144275.COCOR_04957	1.029e-08	68.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS3_k127_3318150_10	1122137.AQXF01000001_gene3029	1.372e-52	203.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1253 Hemolysins and related proteins containing CBS domains	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
CMS3_k127_3318150_11	1121428.DESHY_160093___1	4.658e-33	147.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS3_k127_3318150_19	575540.Isop_2854	0.0008945	50.0	COG1595@1|root,COG1595@2|Bacteria,2J08Y@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3318150_3	1121472.AQWN01000007_gene1144	7.628e-108	364.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_3318150_5	1499967.BAYZ01000152_gene1402	3.037e-96	325.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
CMS3_k127_3318150_7	756272.Plabr_2878	2.722e-67	246.0	COG0265@1|root,COG0265@2|Bacteria,2IY9H@203682|Planctomycetes	203682|Planctomycetes	O	typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_3318150_0	765869.BDW_01400	1.033e-303	958.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,42PYN@68525|delta/epsilon subdivisions,2MTR4@213481|Bdellovibrionales,2WS4X@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS3_k127_3318150_2	247490.KSU1_B0239	3.119e-125	415.0	COG1160@1|root,COG1160@2|Bacteria,2IWXY@203682|Planctomycetes	203682|Planctomycetes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS3_k127_3332677_1	765420.OSCT_0910	8.556e-53	210.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
CMS3_k127_3332677_0	234267.Acid_1388	4.366e-209	677.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	dppX	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS3_k127_3332677_4	483219.LILAB_15120	8.223e-08	65.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2Z0FT@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD,fn3
CMS3_k127_3332677_2	1147.D082_25660	2.757e-27	130.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
CMS3_k127_3332677_3	243090.RB621	4.839e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_3344422_15	861299.J421_0781	3.281e-15	86.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
CMS3_k127_3344422_10	661478.OP10G_3413	1.508e-52	200.0	2ESU2@1|root,33KCH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS3_k127_3344422_0	1297742.A176_00650	0.0	1545.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,2YYQ8@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
CMS3_k127_3344422_9	292459.STH2747	9.658e-62	242.0	COG1463@1|root,COG2120@1|root,COG1463@2|Bacteria,COG2120@2|Bacteria,1UYPV@1239|Firmicutes,251C1@186801|Clostridia	186801|Clostridia	Q	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_3344422_5	330214.NIDE4355	1.389e-92	318.0	COG0436@1|root,COG0436@2|Bacteria,3J0EV@40117|Nitrospirae	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_3344422_14	575540.Isop_0486	2.128e-15	89.0	COG2304@1|root,COG2304@2|Bacteria,2IZSI@203682|Planctomycetes	203682|Planctomycetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_3344422_16	1094980.Mpsy_1256	2.388e-14	87.0	arCOG03492@1|root,arCOG03492@2157|Archaea,2Y5WG@28890|Euryarchaeota,2NBFI@224756|Methanomicrobia	224756|Methanomicrobia	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
CMS3_k127_3344422_4	671143.DAMO_1044	5.383e-98	333.0	COG0761@1|root,COG0761@2|Bacteria,2NP7K@2323|unclassified Bacteria	2|Bacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4,2.7.4.25	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	M00052,M00096,M00178	R00158,R00512,R01665,R05884,R08210	RC00002,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	iIT341.HP0400,iLJ478.TM1444	LYTB,S1
CMS3_k127_3344422_13	1131814.JAFO01000001_gene4550	5.834e-17	83.0	COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,3F1TX@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	BolA-like protein	bolA2	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS3_k127_3344422_11	533240.CRC_00291	6.004e-27	128.0	COG0278@1|root,COG0278@2|Bacteria,1G6JA@1117|Cyanobacteria,1HNW9@1161|Nostocales	1117|Cyanobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	ycf64	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CMS3_k127_3344422_8	926562.Oweho_2979	1.546e-62	233.0	COG1738@1|root,COG1738@2|Bacteria,4NFP3@976|Bacteroidetes,1HYC6@117743|Flavobacteriia,2PB3P@246874|Cryomorphaceae	976|Bacteroidetes	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS3_k127_3344422_18	1380347.JNII01000009_gene2257	2.525e-11	78.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4ES90@85013|Frankiales	201174|Actinobacteria	I	Carbamoyl-phosphate synthase L chain	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_3344422_3	1128421.JAGA01000002_gene1149	3.766e-144	473.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_3344422_2	1122179.KB890414_gene1744	2.654e-198	625.0	COG0538@1|root,COG0538@2|Bacteria,4PKW6@976|Bacteroidetes,1IPFB@117747|Sphingobacteriia	976|Bacteroidetes	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_3344422_7	31964.CMS0739	2.562e-69	269.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FKJM@85023|Microbacteriaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_3344422_17	405948.SACE_5870	5.718e-13	82.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4DXZY@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_3344422_12	344747.PM8797T_07664	4.421e-20	107.0	COG1305@1|root,COG1305@2|Bacteria,2IZUN@203682|Planctomycetes	203682|Planctomycetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS3_k127_3344422_1	1168034.FH5T_20565	3.759e-314	996.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS3_k127_3344422_20	211114.JOEF01000020_gene685	4.158e-10	72.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4E5J3@85010|Pseudonocardiales	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_3344422_6	1279017.AQYJ01000028_gene2525	2.16e-92	314.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_3344422_19	497964.CfE428DRAFT_5714	2.066e-10	69.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS3_k127_3344422_21	685778.AORL01000013_gene2071	1.91e-07	59.0	COG1403@1|root,COG1403@2|Bacteria,1MZVF@1224|Proteobacteria,2UBUF@28211|Alphaproteobacteria,2K5ZU@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS3_k127_3344422_23	1150864.MILUP08_45419	9.234e-06	57.0	COG4097@1|root,COG4097@2|Bacteria,2GQH2@201174|Actinobacteria,4DD0S@85008|Micromonosporales	201174|Actinobacteria	P	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3347514_3	697282.Mettu_4178	8.078e-65	228.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XFY7@135618|Methylococcales	135618|Methylococcales	S	Haemolysin-III related	-	-	-	-	-	-	-	-	-	-	-	-	HlyIII
CMS3_k127_3347514_2	1121918.ARWE01000001_gene3081	4.342e-117	391.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43V7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_3347514_1	1121918.ARWE01000001_gene3080	7.27e-150	485.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales	68525|delta/epsilon subdivisions	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS3_k127_3347514_0	1121918.ARWE01000001_gene3079	3.452e-213	691.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
CMS3_k127_3347514_4	324831.LGAS_0661	1.358e-14	78.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
CMS3_k127_3349357_1	886293.Sinac_2224	3.986e-163	545.0	28H8P@1|root,2Z7KH@2|Bacteria,2IYE8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3349357_9	190650.CC_0570	2.873e-13	79.0	2E7B7@1|root,331UM@2|Bacteria,1NB58@1224|Proteobacteria,2UHAV@28211|Alphaproteobacteria,2KJYK@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3349357_8	765420.OSCT_2044	1.802e-15	93.0	2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi,375QK@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
CMS3_k127_3349357_3	1280941.HY2_10825	1.234e-100	339.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,43WVJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	AAA ATPase	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_3349357_5	1278073.MYSTI_02860	1.631e-55	212.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,42TVQ@68525|delta/epsilon subdivisions,2WQN4@28221|Deltaproteobacteria,2YV0V@29|Myxococcales	28221|Deltaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_3349357_6	1280944.HY17_14405	6.443e-35	153.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,2U06S@28211|Alphaproteobacteria,43WKZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CMS3_k127_3349357_7	861299.J421_2456	5.377e-17	95.0	COG1300@1|root,COG1714@1|root,COG1300@2|Bacteria,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K06384	-	-	-	-	ko00000	-	-	-	RDD,SpoIIM
CMS3_k127_3349357_0	283699.D172_3805	8.179e-266	841.0	COG0348@1|root,COG0492@1|root,COG0348@2|Bacteria,COG0492@2|Bacteria,1QYEW@1224|Proteobacteria,1T3PI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Pyr_redox_3
CMS3_k127_3349357_2	867845.KI911784_gene2277	2.249e-132	451.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_3349357_10	62928.azo0278	9.054e-07	61.0	2EFNF@1|root,339EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3349357_4	518766.Rmar_2419	5.319e-63	226.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1FKAC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_3352520_4	1049564.TevJSym_ay00030	1.292e-58	215.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,1S3A3@1236|Gammaproteobacteria,1JA3F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.338,1.5.1.21	ko:K13609,ko:K16844	ko00270,ko00310,ko00960,ko01100,ko01120,map00270,map00310,map00960,map01100,map01120	-	R02203,R07137	RC00031,RC00135	ko00000,ko00001,ko01000	-	-	-	Ldh_2
CMS3_k127_3352520_2	1396141.BATP01000060_gene4560	9.235e-94	338.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CMS3_k127_3352520_8	1122603.ATVI01000006_gene548	1.4e-21	111.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S6X1@1236|Gammaproteobacteria,1X450@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_3352520_7	483219.LILAB_28760	1.807e-30	139.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43CJR@68525|delta/epsilon subdivisions,2X7U3@28221|Deltaproteobacteria,2Z3HT@29|Myxococcales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3352520_5	1123242.JH636435_gene889	4.899e-56	219.0	COG1404@1|root,COG1404@2|Bacteria,2IY4U@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8
CMS3_k127_3352520_3	1255043.TVNIR_1344	3.477e-62	222.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria,1WY40@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS3_k127_3352520_1	1242864.D187_008109	1.627e-135	439.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42PV7@68525|delta/epsilon subdivisions,2WKXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS3_k127_3352520_0	1232683.ADIMK_0681	1.858e-184	596.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	Glutaredoxin,PALP
CMS3_k127_3352520_6	1089545.KB913037_gene8954	4.123e-42	170.0	COG3826@1|root,COG3826@2|Bacteria,2GK65@201174|Actinobacteria,4DZV5@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxygenase, catalysing oxidative methylation of damaged DNA	-	-	-	ko:K09990	-	-	-	-	ko00000	-	-	-	Oxygenase-NA
CMS3_k127_338847_2	448385.sce1897	3.407e-07	57.0	2AH4C@1|root,317DX@2|Bacteria,1PYQ3@1224|Proteobacteria,435H7@68525|delta/epsilon subdivisions,2WZUU@28221|Deltaproteobacteria,2Z2SV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_338847_1	391625.PPSIR1_02541	4.347e-09	66.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WQZR@28221|Deltaproteobacteria,2YY8N@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_338847_0	886293.Sinac_6489	7.882e-67	256.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_3402400_5	1144275.COCOR_04417	4.253e-36	156.0	COG0775@1|root,COG1357@1|root,COG2319@1|root,COG0775@2|Bacteria,COG1357@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YU5N@29|Myxococcales	28221|Deltaproteobacteria	T	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,PNP_UDP_1,Pentapeptide,WD40
CMS3_k127_3402400_6	338969.Rfer_4146	0.0001393	52.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2VQPE@28216|Betaproteobacteria,4ADGF@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3402400_2	497964.CfE428DRAFT_1018	3.475e-109	366.0	COG2017@1|root,COG2017@2|Bacteria,46TS8@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS3_k127_3402400_3	452637.Oter_0821	6.601e-108	370.0	COG0667@1|root,COG0667@2|Bacteria,46SYS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_3402400_4	756272.Plabr_1246	5.062e-88	308.0	COG1879@1|root,COG1879@2|Bacteria,2IZC9@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system, periplasmic	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CMS3_k127_3402400_0	1254432.SCE1572_24275	3.966e-169	554.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,42YKP@68525|delta/epsilon subdivisions,2WUQ9@28221|Deltaproteobacteria,2YWFW@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	araG	-	3.6.3.17	ko:K02056,ko:K05776,ko:K10441,ko:K10539,ko:K10542,ko:K10545,ko:K10548	ko02010,map02010	M00189,M00212,M00213,M00214,M00215,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2,3.A.1.2.3,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
CMS3_k127_3402400_1	344747.PM8797T_24596	5.162e-111	368.0	COG1172@1|root,COG1172@2|Bacteria,2IZ57@203682|Planctomycetes	203682|Planctomycetes	P	COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CMS3_k127_3421529_1	1192034.CAP_2190	3.572e-18	95.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,Cu-binding_MopE,OppC_N,RCC1,RCC1_2
CMS3_k127_3421529_3	401053.AciPR4_3903	2.445e-16	94.0	COG2931@1|root,COG3386@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	ASH,CHRD,SGL
CMS3_k127_3421529_2	215803.DB30_0409	6.727e-18	99.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YY0K@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
CMS3_k127_3421529_4	44060.JODL01000013_gene3938	8.782e-05	48.0	2APGC@1|root,31EJ6@2|Bacteria,2GWJ9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
CMS3_k127_3421529_0	640081.Dsui_1522	3.234e-75	266.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS3_k127_3439531_4	595460.RRSWK_01256	1.128e-90	325.0	COG1594@1|root,COG1594@2|Bacteria,2J03M@203682|Planctomycetes	203682|Planctomycetes	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3439531_2	448385.sce3512	5.642e-107	359.0	COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,42Z3U@68525|delta/epsilon subdivisions,2WU4D@28221|Deltaproteobacteria,2YVGW@29|Myxococcales	28221|Deltaproteobacteria	K	COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3439531_1	926550.CLDAP_28000	2.443e-135	443.0	COG0626@1|root,COG0626@2|Bacteria,2G7Q6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_3439531_0	861299.J421_3382	0.0	1060.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1ZU89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_3439531_5	391600.ABRU01000025_gene1082	1.346e-40	166.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria,2KI0D@204458|Caulobacterales	204458|Caulobacterales	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS3_k127_3439531_3	1123242.JH636435_gene1686	1.557e-93	321.0	COG0477@1|root,COG2814@2|Bacteria,2J03V@203682|Planctomycetes	203682|Planctomycetes	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_3439531_6	460265.Mnod_2320	2.775e-33	140.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,1JV04@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_3439531_7	930169.B5T_00053	7.282e-30	132.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,1S8UB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transporter Component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_3442649_4	886293.Sinac_6946	5.176e-31	123.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_3442649_6	648996.Theam_1098	4.23e-13	75.0	COG2165@1|root,COG2165@2|Bacteria,2G43Q@200783|Aquificae	200783|Aquificae	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS3_k127_3442649_3	344747.PM8797T_00407	5.561e-32	127.0	COG3070@1|root,COG3070@2|Bacteria,2J0Y3@203682|Planctomycetes	203682|Planctomycetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS3_k127_3442649_2	309807.SRU_1258	5.718e-96	334.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS3_k127_3442649_9	1121481.AUAS01000005_gene1917	1.176e-06	62.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CMS3_k127_3442649_8	365046.Rta_32480	1.42e-08	68.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
CMS3_k127_3442649_1	187272.Mlg_2346	9.442e-115	385.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
CMS3_k127_3442649_0	1129794.C427_1223	5.958e-186	614.0	COG2706@1|root,COG3391@1|root,COG3637@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,COG3637@2|Bacteria,1QWRQ@1224|Proteobacteria,1T4S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3442649_5	246197.MXAN_0146	1.242e-13	85.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_3442649_7	756272.Plabr_0828	3.087e-11	78.0	COG1595@1|root,COG1595@2|Bacteria,2IZPG@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3444712_59	405948.SACE_3751	2.678e-05	52.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria,4E66I@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS3_k127_3444712_13	745014.OMB55_00013610	9.478e-110	372.0	COG4145@1|root,COG4145@2|Bacteria,1QUAY@1224|Proteobacteria,1RP9P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	panF	GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015233,GO:0015238,GO:0015291,GO:0015293,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0015887,GO:0015893,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0072349,GO:0090482,GO:0098656,GO:1903825,GO:1905039	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	iE2348C_1286.E2348C_3528,iECED1_1282.ECED1_3917,iECP_1309.ECP_3351	SSF
CMS3_k127_3444712_14	1123252.ATZF01000027_gene1612	4.31e-107	379.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS3_k127_3444712_18	671143.DAMO_1946	2.907e-100	364.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CMS3_k127_3444712_16	760192.Halhy_3824	3.734e-106	374.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_3444712_11	1487953.JMKF01000028_gene1341	7.48e-111	373.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1H99G@1150|Oscillatoriales	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_3444712_32	443144.GM21_1695	2.66e-43	167.0	COG2391@1|root,COG2391@2|Bacteria,1R5DN@1224|Proteobacteria,42RX6@68525|delta/epsilon subdivisions,2WNK5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_3444712_34	344747.PM8797T_29498	5.023e-39	158.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS3_k127_3444712_10	243090.RB9119	1.362e-118	413.0	COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes	203682|Planctomycetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS3_k127_3444712_55	2074.JNYD01000016_gene4254	1.967e-07	64.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4E0FQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
CMS3_k127_3444712_23	404589.Anae109_2588	4.482e-68	246.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS3_k127_3444712_60	1238182.C882_3632	0.0004649	49.0	COG1595@1|root,COG1595@2|Bacteria,1N1F5@1224|Proteobacteria,2UH0S@28211|Alphaproteobacteria,2JU5D@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3444712_45	1430440.MGMSRv2_2631	1.073e-11	79.0	COG1520@1|root,COG1520@2|Bacteria,1QV8R@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3444712_33	411154.GFO_1836	3.122e-41	176.0	COG1520@1|root,COG2304@1|root,COG2911@1|root,COG3209@1|root,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SprB
CMS3_k127_3444712_29	378806.STAUR_2130	1.168e-50	205.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YY1Q@29|Myxococcales	28221|Deltaproteobacteria	KLT	Phosphotransferase enzyme family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pkinase_Tyr,WD40
CMS3_k127_3444712_49	768704.Desmer_2280	3.735e-10	64.0	COG1595@1|root,COG1595@2|Bacteria,1V3G9@1239|Firmicutes,24G1Y@186801|Clostridia,265JM@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigZ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3444712_21	1386089.N865_08430	1.012e-72	271.0	COG4947@1|root,COG4947@2|Bacteria,2I9H9@201174|Actinobacteria,4FFF6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_3444712_15	313589.JNB_06804	2.77e-106	362.0	COG0189@1|root,COG0189@2|Bacteria,2I5WV@201174|Actinobacteria,4FF3F@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3444712_9	1032480.MLP_53040	1.489e-123	409.0	COG2382@1|root,COG2382@2|Bacteria,2HJEA@201174|Actinobacteria,4DSCH@85009|Propionibacteriales	201174|Actinobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CMS3_k127_3444712_30	1380393.JHVP01000005_gene3586	1.577e-49	191.0	COG3340@1|root,COG3340@2|Bacteria,2IGG2@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
CMS3_k127_3444712_7	1380393.JHVP01000005_gene3589	1.996e-135	455.0	COG1181@1|root,COG1181@2|Bacteria,2I7XS@201174|Actinobacteria,4EWIZ@85013|Frankiales	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	ATP-grasp,ATP-grasp_4,Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_3444712_8	1380393.JHVP01000005_gene3588	1.996e-131	433.0	COG1181@1|root,COG1181@2|Bacteria,2I7XS@201174|Actinobacteria,4EWIZ@85013|Frankiales	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	ATP-grasp_4,Dala_Dala_lig_C,Dala_Dala_lig_N
CMS3_k127_3444712_24	309807.SRU_1451	1.487e-66	255.0	COG3920@1|root,COG3920@2|Bacteria,4NINT@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,TPR_12
CMS3_k127_3444712_43	1218075.BAYA01000016_gene4493	1.267e-17	99.0	COG3707@1|root,COG5002@1|root,COG3707@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WH0H@28216|Betaproteobacteria,1KIGC@119060|Burkholderiaceae	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
CMS3_k127_3444712_22	743299.Acife_0999	1.17e-69	271.0	COG4671@1|root,COG4671@2|Bacteria,1N1PQ@1224|Proteobacteria,1S4W5@1236|Gammaproteobacteria,2NDNC@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
CMS3_k127_3444712_42	1210046.B277_13909	1.402e-18	102.0	COG3173@1|root,COG3173@2|Bacteria,2I5QH@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_3444712_1	1173026.Glo7428_4406	7.574e-191	622.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_3444712_61	177437.HRM2_21210	0.0006136	53.0	COG3210@1|root,COG3210@2|Bacteria,1QWN8@1224|Proteobacteria,42TGT@68525|delta/epsilon subdivisions,2WQPA@28221|Deltaproteobacteria,2MPJQ@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3444712_54	1230460.C495_16870	5.26e-08	66.0	arCOG02499@1|root,arCOG02521@1|root,arCOG04500@1|root,arCOG07560@1|root,arCOG02499@2157|Archaea,arCOG02521@2157|Archaea,arCOG04500@2157|Archaea,arCOG07560@2157|Archaea	2157|Archaea	Q	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,Glyco_hydro_28,NosD,PKD,Pectate_lyase_3
CMS3_k127_3444712_20	397278.JOJN01000001_gene2784	3.739e-78	276.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DSH1@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3444712_28	42256.RradSPS_2704	1.134e-51	211.0	COG0438@1|root,COG0438@2|Bacteria,2ID3T@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS3_k127_3444712_35	1116472.MGMO_162c00110	2.345e-38	168.0	2A2RR@1|root,30R50@2|Bacteria,1N915@1224|Proteobacteria,1SJ4K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alginate export	-	-	-	ko:K16081	-	-	-	-	ko00000,ko02000	1.B.13.1	-	-	Alginate_exp
CMS3_k127_3444712_48	1229780.BN381_330001	2.04e-10	74.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,2IFXI@201174|Actinobacteria	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_3444712_53	1121324.CLIT_5c00410	1.736e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1V96X@1239|Firmicutes,24AK3@186801|Clostridia,25QFT@186804|Peptostreptococcaceae	186801|Clostridia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
CMS3_k127_3444712_6	880073.Calab_3584	9.354e-143	469.0	COG0297@1|root,COG0297@2|Bacteria,2NQKG@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CMS3_k127_3444712_3	1380370.JIBA01000010_gene2593	8.32e-153	521.0	COG0189@1|root,COG0189@2|Bacteria,2I75I@201174|Actinobacteria,4FEMX@85021|Intrasporangiaceae	201174|Actinobacteria	HJ	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2
CMS3_k127_3444712_52	1280950.HJO_13836	2.045e-09	67.0	COG0625@1|root,COG0625@2|Bacteria,1PENB@1224|Proteobacteria,2TRVC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CMS3_k127_3444712_25	1192034.CAP_0766	2.475e-66	232.0	COG0640@1|root,COG0640@2|Bacteria,1RCIH@1224|Proteobacteria	1224|Proteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_3444712_26	1192034.CAP_0765	9.782e-66	241.0	COG3832@1|root,COG3832@2|Bacteria,1R428@1224|Proteobacteria	1224|Proteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_3444712_51	861530.ALOZ01000075_gene1339	1.479e-09	68.0	COG3832@1|root,COG3832@2|Bacteria,1V587@1239|Firmicutes,4HJ9S@91061|Bacilli,4GZEU@90964|Staphylococcaceae	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_3444712_37	68570.DC74_7750	3.359e-33	139.0	COG3832@1|root,COG3832@2|Bacteria,2INTA@201174|Actinobacteria	201174|Actinobacteria	DTZ	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_3444712_5	864702.OsccyDRAFT_3746	6.036e-143	471.0	COG1222@1|root,COG1222@2|Bacteria,1G1TR@1117|Cyanobacteria,1H87N@1150|Oscillatoriales	2|Bacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,ClpS
CMS3_k127_3444712_44	530564.Psta_3753	3.237e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3444712_41	264201.pc1031	2.188e-21	111.0	COG4886@1|root,COG4886@2|Bacteria,2JGIV@204428|Chlamydiae	204428|Chlamydiae	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTB,LRR_1,LRR_6
CMS3_k127_3444712_47	382464.ABSI01000006_gene839	1.826e-10	66.0	COG0607@1|root,315D1@2|Bacteria,46TC5@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS3_k127_3444712_36	880073.Calab_3577	2.093e-34	143.0	COG3848@1|root,COG3848@2|Bacteria	2|Bacteria	GT	kinase activity	-	-	2.7.3.13,2.7.9.1,2.7.9.2	ko:K01006,ko:K01007,ko:K22424	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1080,PEP-utilizers,PPDK_N
CMS3_k127_3444712_56	1541065.JRFE01000001_gene2571	8.994e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,1G34M@1117|Cyanobacteria,3VK9Q@52604|Pleurocapsales	1117|Cyanobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_3444712_4	1487953.JMKF01000041_gene3114	5.631e-149	496.0	COG0212@1|root,COG0212@2|Bacteria,1G2B2@1117|Cyanobacteria,1H86T@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3444712_40	583355.Caka_2250	1.541e-23	112.0	COG5074@1|root,COG5074@2|Bacteria,46W5A@74201|Verrucomicrobia,3K8CX@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3444712_31	1201293.AKXQ01000016_gene3529	9.238e-45	177.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_3444712_57	518766.Rmar_2226	2.215e-06	59.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,1FJI7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3444712_17	204669.Acid345_2310	5.8e-105	374.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_3444712_39	118166.JH976537_gene1196	4.701e-26	126.0	COG1262@1|root,COG1262@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H92Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_3444712_50	360094.PXO_01544	4.052e-10	72.0	COG1928@1|root,COG1928@2|Bacteria,1RBY3@1224|Proteobacteria,1T45C@1236|Gammaproteobacteria,1X8ZG@135614|Xanthomonadales	135614|Xanthomonadales	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3444712_12	671143.DAMO_1946	9.988e-111	389.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CMS3_k127_3444712_46	65497.JODV01000009_gene2869	8.099e-11	75.0	COG3675@1|root,COG3675@2|Bacteria,2HBD6@201174|Actinobacteria,4E1XY@85010|Pseudonocardiales	201174|Actinobacteria	I	Lipase (class 3)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
CMS3_k127_3444712_2	1163408.UU9_03358	1.566e-158	505.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,1X32H@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS3_k127_3444712_19	1210908.HSB1_23050	8.908e-82	307.0	COG1409@1|root,arCOG01153@2157|Archaea,2Y2IT@28890|Euryarchaeota,23Z18@183963|Halobacteria	183963|Halobacteria	S	Serine threonine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_3444712_0	1403819.BATR01000183_gene6345	1.206e-268	861.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,DUF1080,HEAT_2,PmoA,ThuA
CMS3_k127_3448395_0	1254432.SCE1572_22375	1.33e-38	167.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3481882_1	1120936.KB907210_gene5819	2.903e-18	96.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4EFN3@85012|Streptosporangiales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0414c	TMP-TENI
CMS3_k127_3481882_0	869210.Marky_1886	2.42e-61	216.0	COG0178@1|root,COG0178@2|Bacteria,1WI7J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_3496007_1	640081.Dsui_0978	4.234e-27	121.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VQJ1@28216|Betaproteobacteria,2KZTF@206389|Rhodocyclales	206389|Rhodocyclales	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS3_k127_3496007_0	251221.35214774	5.706e-106	385.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
CMS3_k127_3496007_2	323848.Nmul_A0987	1.603e-24	122.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VWW5@28216|Betaproteobacteria,3741Z@32003|Nitrosomonadales	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS3_k127_3496007_3	530564.Psta_3393	3.113e-12	76.0	COG1595@1|root,COG1595@2|Bacteria,2IZXA@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3502577_1	344747.PM8797T_09879	1.497e-111	375.0	COG1914@1|root,COG1914@2|Bacteria,2IZ88@203682|Planctomycetes	203682|Planctomycetes	P	Cytochrome ba3-putative manganese transport protein mntH	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS3_k127_3502577_2	1396141.BATP01000009_gene2648	7.984e-70	262.0	COG1082@1|root,COG1082@2|Bacteria,46V1E@74201|Verrucomicrobia,2IVJ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS3_k127_3502577_0	861299.J421_0086	5.56e-116	379.0	COG0329@1|root,COG0329@2|Bacteria,1ZTEC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507831_6	1403819.BATR01000092_gene2658	1.673e-172	554.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3507831_0	1123242.JH636435_gene2266	0.0	1182.0	COG2010@1|root,COG2010@2|Bacteria,2J24D@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CMS3_k127_3507831_5	1123242.JH636435_gene2265	4.559e-180	623.0	COG4102@1|root,COG4102@2|Bacteria,2J285@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_3507831_17	1353529.M899_0997	1.252e-20	108.0	28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,42QRB@68525|delta/epsilon subdivisions,2MSX5@213481|Bdellovibrionales,2WMSD@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Protein of unknown function (DUF3750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3750
CMS3_k127_3507831_9	118163.Ple7327_4340	3.874e-145	486.0	COG0463@1|root,COG0463@2|Bacteria,1G4BG@1117|Cyanobacteria,3VJC0@52604|Pleurocapsales	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3507831_13	234267.Acid_7492	2.844e-78	282.0	28P7U@1|root,2ZC21@2|Bacteria,3Y7PG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507831_12	240016.ABIZ01000001_gene1362	4.743e-94	316.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_3507831_11	595460.RRSWK_03568	1.917e-95	354.0	COG1520@1|root,COG1520@2|Bacteria,2IWVC@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_3507831_2	886293.Sinac_0956	1.423e-279	908.0	COG2010@1|root,COG2010@2|Bacteria,2IWY5@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PA14,PSCyt1,PSCyt2,PSD1
CMS3_k127_3507831_4	344747.PM8797T_00639	1.42e-214	676.0	COG4102@1|root,COG4102@2|Bacteria,2IXAC@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_3507831_20	1047013.AQSP01000122_gene2233	1.269e-11	76.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS3_k127_3507831_7	1122939.ATUD01000001_gene577	1.196e-165	560.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507831_22	448385.sce1844	9.159e-06	59.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_3507831_23	525268.HMPREF0308_1598	1.59e-05	59.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,22M2A@1653|Corynebacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_3507831_14	448385.sce2570	3.55e-59	222.0	COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria,2YVNH@29|Myxococcales	28221|Deltaproteobacteria	K	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
CMS3_k127_3507831_8	344747.PM8797T_20983	4.478e-160	517.0	COG1520@1|root,COG1520@2|Bacteria,2J213@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_3507831_18	583355.Caka_2366	2.906e-14	84.0	2ENVX@1|root,33GGY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507831_24	856793.MICA_254	0.00035	53.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,4BPF3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,PDZ_2,Peptidase_S41
CMS3_k127_3507831_15	1192034.CAP_4484	2.93e-52	207.0	COG1621@1|root,COG1807@1|root,COG1621@2|Bacteria,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507831_3	756272.Plabr_3595	5.903e-220	708.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_3507831_1	756272.Plabr_3596	0.0	1041.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CMS3_k127_3507831_16	756272.Plabr_2435	1.747e-34	153.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159,Prenyltrans
CMS3_k127_3507831_21	1229909.NSED_03765	5.97e-08	65.0	arCOG08764@1|root,arCOG08798@2157|Archaea,41SZ3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507831_10	886293.Sinac_7030	4.606e-124	413.0	COG2755@1|root,COG2755@2|Bacteria,2J56A@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3507831_19	448385.sce6671	3.188e-14	85.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.5.1.28	ko:K01447,ko:K07126,ko:K13582	ko04112,map04112	-	R04112	RC00064,RC00141	ko00000,ko00001,ko01000	-	-	-	LysM,PG_binding_1,Sel1
CMS3_k127_3639185_0	1144310.PMI07_005409	1.055e-82	304.0	COG5652@1|root,COG5652@2|Bacteria,1MX6C@1224|Proteobacteria,2U18Q@28211|Alphaproteobacteria,4BBZB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
CMS3_k127_3639185_3	1142394.PSMK_17190	2.731e-30	128.0	COG1057@1|root,COG1057@2|Bacteria,2IZMU@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_3639185_4	1070319.CAGGBEG34_260027	4.279e-20	104.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VNAG@28216|Betaproteobacteria,1K2YP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 4	wbiH	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS3_k127_3639185_1	997346.HMPREF9374_0673	1.348e-81	289.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,27AUB@186824|Thermoactinomycetaceae	91061|Bacilli	S	Insulinase (Peptidase family M16)	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_3639185_2	1087448.Eab7_0991	2.366e-39	169.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli	91061|Bacilli	S	Peptidase M16	XK27_01960	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
CMS3_k127_366323_3	469383.Cwoe_0762	1.532e-17	98.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_366323_1	331869.BAL199_06279	2.819e-163	537.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TRQ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the peptidase M24B family	pepE	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_366323_2	290397.Adeh_0342	1.116e-71	255.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737	UbiA
CMS3_k127_366323_0	1041930.Mtc_1902	4.924e-211	673.0	COG0318@1|root,arCOG00856@2157|Archaea,2XSZG@28890|Euryarchaeota,2N90V@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3667062_0	641524.ADICYQ_5324	4.263e-60	224.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,47KJR@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
CMS3_k127_3667062_1	1123255.JHYS01000016_gene1091	8.781e-21	103.0	COG2340@1|root,COG3055@1|root,COG4447@1|root,COG2340@2|Bacteria,COG3055@2|Bacteria,COG4447@2|Bacteria,1R14N@1224|Proteobacteria,2WHZ9@28216|Betaproteobacteria,4AIB3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3688024_16	94624.Bpet2384	4.838e-30	128.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2WEA7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
CMS3_k127_3688024_6	1047013.AQSP01000116_gene1112	3.01e-92	323.0	COG2605@1|root,COG2605@2|Bacteria,2NP6Q@2323|unclassified Bacteria	2|Bacteria	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_3688024_11	765420.OSCT_1275	1.943e-52	205.0	COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3688024_20	1136417.AZWE01000042_gene142	9.894e-11	69.0	2BS8F@1|root,32M9W@2|Bacteria,2H6V5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3688024_3	391625.PPSIR1_17005	3.721e-156	507.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2YUN7@29|Myxococcales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M17
CMS3_k127_3688024_2	1379270.AUXF01000005_gene716	1.52e-175	593.0	COG0308@1|root,COG0308@2|Bacteria,1ZUSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ERAP1-like C-terminal domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
CMS3_k127_3688024_5	246195.DNO_0675	2.277e-104	359.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	twitching motility protein	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_3688024_0	1123508.JH636440_gene2030	1.127e-267	839.0	COG1032@1|root,COG1032@2|Bacteria,2IY6B@203682|Planctomycetes	203682|Planctomycetes	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
CMS3_k127_3688024_10	589865.DaAHT2_2138	6.888e-54	214.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	68525|delta/epsilon subdivisions	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS3_k127_3688024_17	589865.DaAHT2_2139	3.031e-25	124.0	COG2911@1|root,COG2911@2|Bacteria,1PQTA@1224|Proteobacteria,42PYT@68525|delta/epsilon subdivisions,2WIZ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS3_k127_3688024_14	1356852.N008_01765	2.404e-40	171.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
CMS3_k127_3688024_21	215803.DB30_4865	1.008e-08	67.0	COG4927@1|root,COG4927@2|Bacteria,1Q1VZ@1224|Proteobacteria,437I5@68525|delta/epsilon subdivisions,2X2RQ@28221|Deltaproteobacteria,2YZTH@29|Myxococcales	28221|Deltaproteobacteria	S	Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
CMS3_k127_3688024_12	1121861.KB899914_gene2074	2.217e-44	173.0	COG5553@1|root,COG5553@2|Bacteria,1NDMC@1224|Proteobacteria,2UKAN@28211|Alphaproteobacteria,2JZ7P@204441|Rhodospirillales	204441|Rhodospirillales	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3688024_23	391625.PPSIR1_15980	4.372e-07	63.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_35,PD40,Pkinase,Pkinase_Tyr,WD40
CMS3_k127_3688024_7	886293.Sinac_6317	9.969e-82	287.0	COG4102@1|root,COG4102@2|Bacteria,2IXXV@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_3688024_8	1396141.BATP01000003_gene5274	1.104e-80	296.0	COG5492@1|root,COG5492@2|Bacteria,46SD1@74201|Verrucomicrobia,2IVJE@203494|Verrucomicrobiae	74201|Verrucomicrobia	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
CMS3_k127_3688024_15	1396141.BATP01000003_gene5275	4.509e-34	152.0	2FHAY@1|root,34957@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3688024_24	1297742.A176_06239	1.53e-05	57.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,2YU62@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CMS3_k127_3688024_9	287.DR97_4503	3.072e-66	246.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria,1YEX9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_3688024_18	1288484.APCS01000001_gene601	5.155e-23	106.0	COG0824@1|root,COG0824@2|Bacteria,1WKEF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_3688024_22	313595.P700755_002141	3.783e-08	59.0	2ARAZ@1|root,31GKZ@2|Bacteria,4NKJD@976|Bacteroidetes,1I0HH@117743|Flavobacteriia,4C3KJ@83612|Psychroflexus	976|Bacteroidetes	S	Domain of unknown function (DUF3332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3332
CMS3_k127_3688024_19	886293.Sinac_2265	2.867e-22	107.0	COG2520@1|root,COG2520@2|Bacteria,2J555@203682|Planctomycetes	203682|Planctomycetes	J	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_3688024_4	1121373.KB903664_gene2551	3.745e-125	419.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CMS3_k127_3688024_1	344747.PM8797T_03419	2.746e-226	719.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_3688024_25	1312954.KI914846_gene1676	7.111e-05	51.0	COG1409@1|root,COG3055@1|root,COG1409@2|Bacteria,COG3055@2|Bacteria,2GVVJ@201174|Actinobacteria	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
CMS3_k127_3695852_10	344747.PM8797T_19557	5.269e-09	64.0	COG3049@1|root,COG3049@2|Bacteria,2J1Z0@203682|Planctomycetes	203682|Planctomycetes	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3695852_0	1047013.AQSP01000142_gene185	6.763e-211	679.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CMS3_k127_3695852_3	497964.CfE428DRAFT_4366	9.765e-139	455.0	COG1520@1|root,COG1520@2|Bacteria,46TRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_3695852_7	1144275.COCOR_06959	3.455e-22	108.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
CMS3_k127_3695852_6	767434.Fraau_2027	7.801e-23	105.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X6CG@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_3695852_1	1340493.JNIF01000003_gene2016	2.506e-160	523.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria	57723|Acidobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_3695852_4	305900.GV64_13020	1.366e-58	210.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XJSS@135619|Oceanospirillales	135619|Oceanospirillales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS3_k127_3695852_5	945713.IALB_1636	2.248e-27	116.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS3_k127_3695852_9	1192034.CAP_5771	1.07e-19	95.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,4386D@68525|delta/epsilon subdivisions,2X3GA@28221|Deltaproteobacteria,2YVYT@29|Myxococcales	28221|Deltaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
CMS3_k127_3695852_2	1382359.JIAL01000001_gene826	1.469e-151	512.0	COG0443@1|root,COG0443@2|Bacteria,3Y2F8@57723|Acidobacteria,2JIVF@204432|Acidobacteriia	204432|Acidobacteriia	O	heat shock protein 70	-	-	-	ko:K04043,ko:K04044	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33,1.A.33.1	-	-	HSP70
CMS3_k127_3695852_8	1123508.JH636442_gene3885	7.24e-21	109.0	COG0633@1|root,COG0633@2|Bacteria,2J33M@203682|Planctomycetes	203682|Planctomycetes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
CMS3_k127_3698563_2	1396141.BATP01000039_gene1270	3.506e-11	76.0	COG2931@1|root,COG2931@2|Bacteria,46Z9Y@74201|Verrucomicrobia,2IWB4@203494|Verrucomicrobiae	2|Bacteria	Q	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,FG-GAP
CMS3_k127_3698563_3	227882.SAV_4064	5.752e-11	71.0	COG1595@1|root,COG1595@2|Bacteria,2GM5V@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3698563_1	158787.BSCA_1503	1.282e-35	150.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CZQC@85004|Bifidobacteriales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_3698563_0	316274.Haur_0326	1.878e-101	349.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,374U8@32061|Chloroflexia	32061|Chloroflexia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS3_k127_3722882_1	13333.ERN01374	1.695e-61	218.0	COG0460@1|root,2QQBK@2759|Eukaryota,37I0M@33090|Viridiplantae,3G9XD@35493|Streptophyta	35493|Streptophyta	E	Bifunctional aspartokinase homoserine dehydrogenase	AKHSDH1	GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009090,GO:0009092,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
CMS3_k127_3722882_2	309807.SRU_0690	1.637e-60	227.0	COG0083@1|root,COG0083@2|Bacteria,4NE2M@976|Bacteroidetes,1FJFZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_3722882_0	1161401.ASJA01000022_gene140	1.102e-84	295.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria,43X1Y@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Threonine synthase	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CMS3_k127_3742392_5	96561.Dole_2411	2.153e-26	124.0	COG1807@1|root,COG1807@2|Bacteria,1RK4G@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3742392_6	1120950.KB892754_gene6015	5.695e-16	84.0	COG4747@1|root,COG4747@2|Bacteria,2GZWK@201174|Actinobacteria	201174|Actinobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3742392_0	1210884.HG799473_gene14966	5.26e-153	542.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	3.1.4.46,3.2.1.8,4.2.1.118	ko:K01126,ko:K01181,ko:K09483	ko00400,ko00564,ko01110,ko01130,map00400,map00564,map01110,map01130	-	R01030,R01470,R01627	RC00017,RC00425,RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,NosD,PKD
CMS3_k127_3742392_3	880072.Desac_2920	8.57e-41	168.0	COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_3742392_1	316067.Geob_3463	3.354e-133	450.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,43TE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS3_k127_3742392_4	477974.Daud_1379	3.88e-34	141.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,261RV@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS3_k127_3742392_2	1210884.HG799465_gene11914	1.441e-104	351.0	COG0008@1|root,COG0008@2|Bacteria,2IYG3@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS3_k127_3770750_1	756272.Plabr_3432	2.205e-151	487.0	COG4260@1|root,COG4260@2|Bacteria,2IYIR@203682|Planctomycetes	203682|Planctomycetes	S	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339
CMS3_k127_3770750_2	521674.Plim_2000	1.848e-123	408.0	COG1996@1|root,COG1996@2|Bacteria,2J54C@203682|Planctomycetes	203682|Planctomycetes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3770750_3	13690.CP98_04652	3.601e-66	234.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_3770750_0	344747.PM8797T_10979	7.967e-190	632.0	COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_3770750_4	1192034.CAP_4484	1.112e-50	201.0	COG1621@1|root,COG1807@1|root,COG1621@2|Bacteria,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3770750_7	575540.Isop_2341	9.65e-14	86.0	COG1595@1|root,COG1595@2|Bacteria,2IZPG@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3770750_8	479434.Sthe_0511	2.311e-05	58.0	COG1306@1|root,COG1306@2|Bacteria,2G81Y@200795|Chloroflexi,27XJ9@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4015
CMS3_k127_3770750_9	1144275.COCOR_03801	9.163e-05	56.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K12516	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.5.5	-	-	CarboxypepD_reg,SdrD_B
CMS3_k127_3770750_5	1279009.ADICEAN_01947	2.607e-34	154.0	COG2706@1|root,COG3391@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,4PPV8@976|Bacteroidetes,47V28@768503|Cytophagia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_3770750_6	944480.ATUV01000002_gene84	5.336e-19	100.0	COG2050@1|root,COG2050@2|Bacteria,1N8F8@1224|Proteobacteria,42V78@68525|delta/epsilon subdivisions,2WRBA@28221|Deltaproteobacteria,2M7BC@213113|Desulfurellales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_378005_4	448385.sce2570	1.494e-86	310.0	COG5164@1|root,COG5164@2|Bacteria,1N2FU@1224|Proteobacteria,42WNM@68525|delta/epsilon subdivisions,2WRNC@28221|Deltaproteobacteria,2YVNH@29|Myxococcales	28221|Deltaproteobacteria	K	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
CMS3_k127_378005_1	1121904.ARBP01000006_gene3721	7.025e-166	549.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,47NF5@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Sulfatase
CMS3_k127_378005_15	344747.PM8797T_17382	3.145e-13	84.0	2DNHT@1|root,32XKG@2|Bacteria,2J0DX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_378005_8	1403819.BATR01000162_gene5453	6.032e-41	175.0	COG4886@1|root,COG4886@2|Bacteria,46W4C@74201|Verrucomicrobia,2IU85@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6,LRR_8,PSCyt1
CMS3_k127_378005_2	472759.Nhal_0732	8.059e-132	445.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,1WXBE@135613|Chromatiales	135613|Chromatiales	P	PFAM Sodium sulphate symporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS3_k127_378005_9	1242864.D187_002876	2.416e-38	158.0	COG2706@1|root,COG2706@2|Bacteria,1MUKZ@1224|Proteobacteria,4394D@68525|delta/epsilon subdivisions,2X4AE@28221|Deltaproteobacteria,2YYM5@29|Myxococcales	28221|Deltaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
CMS3_k127_378005_10	323098.Nwi_2545	1.966e-34	150.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,3JRIY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	MA20_05655	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_378005_11	575540.Isop_1337	2.871e-31	136.0	COG1560@1|root,COG1560@2|Bacteria,2IY7N@203682|Planctomycetes	203682|Planctomycetes	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_378005_13	1267534.KB906754_gene3020	1.32e-21	107.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS3_k127_378005_5	335659.S23_64850	4.029e-63	235.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,3JTPP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS3_k127_378005_14	861299.J421_2380	1.923e-20	106.0	COG1595@1|root,COG1595@2|Bacteria,1ZSWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_378005_12	1397528.Q671_17340	8.034e-29	130.0	COG1507@1|root,COG1507@2|Bacteria,1RDW4@1224|Proteobacteria,1S5CM@1236|Gammaproteobacteria,1XKAI@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
CMS3_k127_378005_0	344747.PM8797T_20044	1.89e-177	568.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_378005_17	553175.POREN0001_1589	9.253e-06	58.0	COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,2FMMP@200643|Bacteroidia,22WMS@171551|Porphyromonadaceae	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Tricorn_C1
CMS3_k127_378005_3	1443665.JACA01000025_gene3422	5.221e-99	338.0	COG0436@1|root,COG0436@2|Bacteria,4NSBB@976|Bacteroidetes,1IM6I@117743|Flavobacteriia,2YHQE@290174|Aquimarina	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS3_k127_378005_6	575540.Isop_0068	6.059e-56	223.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_378005_7	1037409.BJ6T_57040	3.83e-46	174.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JTJE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
CMS3_k127_3797539_16	110662.Syncc9605_2374	4.853e-07	60.0	2AKF7@1|root,31B6Q@2|Bacteria,1G5KA@1117|Cyanobacteria,1GYRZ@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3797539_6	1219049.SP5_035_00230	3.549e-86	306.0	COG2133@1|root,COG2133@2|Bacteria,1R6DX@1224|Proteobacteria,2VFQF@28211|Alphaproteobacteria,2KCI6@204457|Sphingomonadales	204457|Sphingomonadales	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_3797539_7	1535287.JP74_22580	8.166e-74	257.0	COG3142@1|root,COG3142@2|Bacteria,1MV5W@1224|Proteobacteria,2TTKM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
CMS3_k127_3797539_11	1089553.Tph_c15540	6.68e-26	119.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,42G2S@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_3797539_2	1265505.ATUG01000001_gene4766	1.079e-185	594.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WIUM@28221|Deltaproteobacteria,2MI28@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_3797539_12	1121904.ARBP01000002_gene6681	3.817e-24	114.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS3_k127_3797539_15	404589.Anae109_1820	3.299e-09	69.0	COG2456@1|root,COG2456@2|Bacteria,1NF5Z@1224|Proteobacteria,42VNI@68525|delta/epsilon subdivisions,2WS2M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
CMS3_k127_3797539_9	290397.Adeh_3051	6.255e-58	231.0	COG1216@1|root,COG1216@2|Bacteria,1QW1K@1224|Proteobacteria,43BRI@68525|delta/epsilon subdivisions,2WN0V@28221|Deltaproteobacteria,2Z30Y@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_3797539_4	1242864.D187_006544	5.239e-116	408.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS3_k127_3797539_5	1234364.AMSF01000082_gene2983	2.145e-99	335.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1X3J5@135614|Xanthomonadales	135614|Xanthomonadales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS3_k127_3797539_3	314230.DSM3645_16045	5.441e-164	541.0	COG0793@1|root,COG0793@2|Bacteria,2IXI9@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CMS3_k127_3797539_10	321332.CYB_1964	5.143e-28	124.0	COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,1GYXA@1129|Synechococcus	1117|Cyanobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_3797539_13	391625.PPSIR1_20349	9.611e-14	86.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_3797539_14	1550073.JROH01000016_gene330	6.524e-10	73.0	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,2U89X@28211|Alphaproteobacteria,2K4XM@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3797539_8	1408813.AYMG01000008_gene4034	2.254e-59	220.0	COG0639@1|root,COG0639@2|Bacteria,4NME8@976|Bacteroidetes,1IUY5@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS3_k127_3797539_0	530564.Psta_4256	0.0	1399.0	COG2010@1|root,COG2133@1|root,COG3474@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_3797539_1	243090.RB6538	1.453e-195	628.0	COG4146@1|root,COG4146@2|Bacteria,2J1R6@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_3832900_0	313628.LNTAR_23894	2.728e-54	211.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3832900_1	243090.RB6876	1.035e-13	83.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Lipase_GDSL_2,Metallophos,SASA,SLH
CMS3_k127_3877910_13	1379858.N508_00670	3.974e-73	256.0	COG0528@1|root,COG0528@2|Bacteria,2GEZE@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_3877910_17	648996.Theam_0090	5.224e-62	221.0	COG0264@1|root,COG0264@2|Bacteria,2G3RA@200783|Aquificae	200783|Aquificae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS3_k127_3877910_9	237368.SCABRO_01916	8.007e-78	274.0	COG0052@1|root,COG0052@2|Bacteria,2IY9P@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS3_k127_3877910_30	449447.MAE_12990	5.912e-36	150.0	COG2199@1|root,COG3706@2|Bacteria,1G35Y@1117|Cyanobacteria	1117|Cyanobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	2.7.7.65	ko:K21020	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Response_reg
CMS3_k127_3877910_2	1121904.ARBP01000003_gene6415	4.647e-180	587.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_3877910_21	378806.STAUR_2848	1.593e-50	190.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42UAY@68525|delta/epsilon subdivisions,2X5BX@28221|Deltaproteobacteria,2YV3H@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
CMS3_k127_3877910_18	159749.K0STR7	4.872e-60	216.0	COG0800@1|root,2QVAJ@2759|Eukaryota,2XC3K@2836|Bacillariophyta	2836|Bacillariophyta	G	KDPG and KHG aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase
CMS3_k127_3877910_8	448385.sce7344	1.696e-111	378.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,2YYNR@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_3877910_31	945713.IALB_0804	1.438e-35	154.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
CMS3_k127_3877910_32	1121904.ARBP01000010_gene2339	1.76e-27	129.0	COG3369@1|root,COG3369@2|Bacteria,4NW9E@976|Bacteroidetes,47W0Y@768503|Cytophagia	976|Bacteroidetes	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CMS3_k127_3877910_15	933262.AXAM01000118_gene2902	5.26e-71	246.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,42R54@68525|delta/epsilon subdivisions,2WMNZ@28221|Deltaproteobacteria,2MJJV@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM ThiJ PfpI domain protein	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS3_k127_3877910_0	1232410.KI421414_gene2810	0.0	1022.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,43TX4@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3458_C) ARM repeats	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,HEAT_2,Peptidase_M1
CMS3_k127_3877910_28	671143.DAMO_0193	5.858e-38	156.0	COG1596@1|root,COG1596@2|Bacteria,2NPNM@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide export protein	gumB	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS3_k127_3877910_11	1499967.BAYZ01000066_gene6078	6.664e-76	282.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
CMS3_k127_3877910_38	629773.AORY01000002_gene1450	1.313e-05	60.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,2U6JI@28211|Alphaproteobacteria,2K3WT@204457|Sphingomonadales	204457|Sphingomonadales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_3877910_22	586416.GZ22_15515	5.407e-50	194.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli	91061|Bacilli	M	transferase	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS3_k127_3877910_34	886293.Sinac_2958	4.636e-16	93.0	COG0726@1|root,COG0726@2|Bacteria,2J29E@203682|Planctomycetes	203682|Planctomycetes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877910_35	644966.Tmar_1264	3.894e-15	86.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,2495M@186801|Clostridia,3WD0G@538999|Clostridiales incertae sedis	186801|Clostridia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_3877910_39	1134912.AJTV01000010_gene676	7.905e-05	55.0	COG5653@1|root,COG5653@2|Bacteria,1R6YM@1224|Proteobacteria,2U1RN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS3_k127_3877910_27	1209989.TepiRe1_0855	5.122e-42	171.0	COG0438@1|root,COG0438@2|Bacteria,1TQNE@1239|Firmicutes,24F3V@186801|Clostridia,42J9W@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_3877910_36	240302.BN982_00177	1.034e-09	70.0	COG3307@1|root,COG3307@2|Bacteria,1U5EQ@1239|Firmicutes,4IF6C@91061|Bacilli,3NG28@45667|Halobacillus	91061|Bacilli	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS3_k127_3877910_37	644282.Deba_1174	5.085e-08	64.0	COG2242@1|root,COG2242@2|Bacteria,1QX6B@1224|Proteobacteria,43BYX@68525|delta/epsilon subdivisions,2WSZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_3877910_23	1246445.ANAY01000013_gene141	1.362e-47	190.0	COG0500@1|root,COG2226@2|Bacteria,2IMHF@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_3877910_12	926550.CLDAP_10390	1.032e-73	273.0	COG0438@1|root,COG0438@2|Bacteria,2G7TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.346,2.4.1.348	ko:K12995,ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3877910_25	215803.DB30_3201	1.545e-43	183.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,43AHD@68525|delta/epsilon subdivisions,2X5XJ@28221|Deltaproteobacteria,2YXYK@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_3877910_29	485917.Phep_3582	1.356e-36	158.0	COG2755@1|root,COG2755@2|Bacteria,4NYHM@976|Bacteroidetes,1IX93@117747|Sphingobacteriia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_3877910_4	344747.PM8797T_29708	1.86e-151	501.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
CMS3_k127_3877910_19	886293.Sinac_3944	2.866e-58	213.0	COG1595@1|root,COG1595@2|Bacteria,2IZS9@203682|Planctomycetes	203682|Planctomycetes	K	RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r4_2
CMS3_k127_3877910_5	886293.Sinac_2100	3.995e-126	457.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_3877910_40	533240.CRC_02888	9.367e-05	56.0	COG0694@1|root,COG0822@1|root,COG2906@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,COG2906@2|Bacteria,1G04Q@1117|Cyanobacteria,1HJEQ@1161|Nostocales	1117|Cyanobacteria	COP	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
CMS3_k127_3877910_7	589865.DaAHT2_1752	2.523e-117	395.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ00@28221|Deltaproteobacteria,2MJIZ@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS3_k127_3877910_20	414684.RC1_0395	7.549e-55	200.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2TUR9@28211|Alphaproteobacteria,2JSEA@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3877910_6	414684.RC1_2236	3.022e-119	395.0	COG2267@1|root,COG2267@2|Bacteria,1QU3E@1224|Proteobacteria,2TVXS@28211|Alphaproteobacteria,2JQNK@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_3877910_3	313628.LNTAR_22844	1.063e-179	583.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Lipase_GDSL_2,Peptidase_S9
CMS3_k127_3877910_1	1237149.C900_05550	3.982e-257	816.0	COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_3877910_24	981369.JQMJ01000004_gene4889	9.026e-46	185.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria,2NH27@228398|Streptacidiphilus	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_3877910_33	1340493.JNIF01000004_gene369	1.193e-19	100.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
CMS3_k127_3877910_14	1122915.AUGY01000014_gene2783	2.26e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,274QP@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS3_k127_3877910_10	661478.OP10G_2046	2.95e-76	282.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_3877910_16	383372.Rcas_0458	1.897e-64	251.0	COG0438@1|root,COG0438@2|Bacteria,2G7Z3@200795|Chloroflexi,376IC@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3877910_26	1128421.JAGA01000001_gene2321	1.624e-42	173.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_3925280_4	243090.RB11142	1.106e-76	267.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_3925280_5	344747.PM8797T_00337	1.098e-29	130.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
CMS3_k127_3925280_0	1499967.BAYZ01000076_gene756	1.267e-138	445.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_3925280_3	344747.PM8797T_15161	1.01e-101	348.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_3925280_1	865861.AZSU01000006_gene1375	7.108e-119	397.0	COG0031@1|root,COG0031@2|Bacteria,1UZEQ@1239|Firmicutes,24BCR@186801|Clostridia,36G6F@31979|Clostridiaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3925280_2	502025.Hoch_5169	6.319e-111	369.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
CMS3_k127_3925280_6	226899.F0XB90	0.0001032	45.0	COG0473@1|root,KOG0785@2759|Eukaryota,38B8U@33154|Opisthokonta,3NV1E@4751|Fungi,3QNKE@4890|Ascomycota	4751|Fungi	E	Tartrate dehydrogenase	-	-	-	ko:K10862	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Iso_dh
CMS3_k127_3932618_4	1144275.COCOR_05577	3.363e-85	317.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CMS3_k127_3932618_1	439235.Dalk_5144	1.669e-156	511.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MHPE@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS3_k127_3932618_9	316067.Geob_0896	8.548e-48	196.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_3932618_16	889378.Spiaf_0316	3.234e-20	100.0	COG1762@1|root,COG1762@2|Bacteria,2J7FM@203691|Spirochaetes	203691|Spirochaetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS3_k127_3932618_8	1294143.H681_12175	2.825e-48	199.0	COG0421@1|root,COG0421@2|Bacteria,1QVJA@1224|Proteobacteria,1RYYT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS3_k127_3932618_10	521674.Plim_2592	3.776e-47	184.0	COG0394@1|root,COG0394@2|Bacteria,2IX5F@203682|Planctomycetes	203682|Planctomycetes	T	Belongs to the SUA5 family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc,Sua5_yciO_yrdC
CMS3_k127_3932618_7	886293.Sinac_2630	5.519e-54	199.0	COG5000@1|root,COG5000@2|Bacteria,2IZCJ@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_3932618_2	575540.Isop_3482	2.151e-125	419.0	COG2204@1|root,COG2204@2|Bacteria,2IWYY@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_3932618_5	502025.Hoch_0164	1.475e-73	280.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,1Q385@1224|Proteobacteria,433YW@68525|delta/epsilon subdivisions,2X44A@28221|Deltaproteobacteria,2YY7W@29|Myxococcales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_3932618_17	1122939.ATUD01000013_gene887	1.513e-09	72.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CPFC@84995|Rubrobacteria	84995|Rubrobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS3_k127_3932618_12	1123251.ATWM01000007_gene2369	1.402e-34	144.0	COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4FG27@85021|Intrasporangiaceae	201174|Actinobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
CMS3_k127_3932618_14	396588.Tgr7_1828	2.33e-27	128.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,1WW0S@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, delta'	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS3_k127_3932618_15	349741.Amuc_0118	1.198e-25	111.0	2E5IJ@1|root,3309Y@2|Bacteria,46YZF@74201|Verrucomicrobia,2IUSS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3932618_6	269799.Gmet_1853	5.3e-61	238.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,43SVH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_3932618_11	1296990.H845_1902	2.464e-43	165.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2JS81@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS3_k127_3932618_3	1336208.JADY01000001_gene1081	3.556e-108	359.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_3932618_13	977880.RALTA_A2646	3.263e-30	129.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,1K707@119060|Burkholderiaceae	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS3_k127_3932618_0	452637.Oter_1675	8.211e-174	557.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,3K78R@414999|Opitutae	414999|Opitutae	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS3_k127_3932875_1	373994.Riv7116_6097	5.137e-106	371.0	COG0457@1|root,COG1672@1|root,COG2319@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HMFW@1161|Nostocales	1117|Cyanobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS3_k127_3932875_10	65497.JODV01000007_gene395	2.014e-20	98.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4DY2F@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_3932875_8	344747.PM8797T_10694	8.02e-51	204.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_3932875_12	1168289.AJKI01000002_gene2514	0.0001205	56.0	COG1141@1|root,COG1141@2|Bacteria,4P7D9@976|Bacteroidetes,2FZ83@200643|Bacteroidia	976|Bacteroidetes	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
CMS3_k127_3932875_9	1122918.KB907252_gene2915	1.435e-22	112.0	COG0737@1|root,COG2340@1|root,COG0737@2|Bacteria,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,4HRX1@91061|Bacilli,26UWX@186822|Paenibacillaceae	91061|Bacilli	O	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	CAP,SLH
CMS3_k127_3932875_11	1120965.AUBV01000010_gene2894	0.0001048	55.0	COG2849@1|root,COG2849@2|Bacteria,4NUVT@976|Bacteroidetes,47XGD@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
CMS3_k127_3932875_2	1254432.SCE1572_35290	4.497e-101	342.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,43AB6@68525|delta/epsilon subdivisions,2X259@28221|Deltaproteobacteria,2YZEP@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_3932875_3	926554.KI912660_gene2396	6.74e-97	327.0	COG0604@1|root,COG0604@2|Bacteria,1WI1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_3932875_5	518766.Rmar_1550	2.164e-74	268.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	paaA	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_3932875_4	543526.Htur_0504	9.825e-79	281.0	COG1250@1|root,arCOG00250@2157|Archaea,2XT9S@28890|Euryarchaeota,23TDY@183963|Halobacteria	183963|Halobacteria	I	3-hydroxyacyl-CoA dehydrogenase	hbd1	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_3932875_7	1123242.JH636435_gene1579	4.92e-58	222.0	28JEC@1|root,2Z98J@2|Bacteria,2IX0J@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3932875_6	1123276.KB893270_gene4724	6.797e-70	246.0	COG1409@1|root,COG1409@2|Bacteria,4NRDF@976|Bacteroidetes,47VTX@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K21814	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	Metallophos
CMS3_k127_3932875_0	234267.Acid_7828	5.345e-219	715.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS3_k127_394181_2	1304872.JAGC01000005_gene1934	4.653e-13	76.0	COG0697@1|root,COG0697@2|Bacteria,1NCEQ@1224|Proteobacteria,43AZZ@68525|delta/epsilon subdivisions,2X6E2@28221|Deltaproteobacteria,2MH1V@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_394181_3	575540.Isop_0409	1.566e-09	70.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
CMS3_k127_394181_1	794903.OPIT5_30680	7.556e-61	223.0	COG5459@1|root,COG5459@2|Bacteria,46SNP@74201|Verrucomicrobia,3K8YT@414999|Opitutae	414999|Opitutae	J	Ribosomal small subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
CMS3_k127_394181_0	497964.CfE428DRAFT_0769	2.109e-74	260.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_3947098_8	443143.GM18_1938	1.301e-81	285.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PYA@68525|delta/epsilon subdivisions,2WKM5@28221|Deltaproteobacteria,43SWI@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_3947098_20	379066.GAU_1412	1.147e-15	93.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
CMS3_k127_3947098_23	1122218.KB893654_gene2064	0.0007809	53.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1520 FOG WD40-like repeat	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS3_k127_3947098_2	696369.KI912183_gene1168	1.628e-171	561.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,2614W@186807|Peptococcaceae	186801|Clostridia	J	class II (D K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_3947098_4	443254.Marpi_1118	2.012e-106	372.0	COG1757@1|root,COG1757@2|Bacteria,2GC30@200918|Thermotogae	200918|Thermotogae	C	PFAM Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
CMS3_k127_3947098_6	443143.GM18_3901	5.621e-97	332.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42M2V@68525|delta/epsilon subdivisions,2WKEB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA methylase	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CMS3_k127_3947098_13	765420.OSCT_1998	4.506e-37	161.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_3947098_11	265072.Mfla_2190	1.666e-49	181.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2VT5I@28216|Betaproteobacteria,2KMR1@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_3947098_15	1317122.ATO12_19925	1.314e-29	133.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,1I5GG@117743|Flavobacteriia,2YHKP@290174|Aquimarina	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS3_k127_3947098_7	502025.Hoch_6744	1.525e-94	316.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,42P41@68525|delta/epsilon subdivisions,2WM40@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_3947098_21	1396141.BATP01000027_gene1057	9.75e-12	78.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,Laminin_G_3,SLH
CMS3_k127_3947098_17	1122134.KB893650_gene1446	3.021e-24	115.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1S2JW@1236|Gammaproteobacteria,1XM6A@135619|Oceanospirillales	135619|Oceanospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF676
CMS3_k127_3947098_9	391625.PPSIR1_40300	5.936e-55	202.0	COG4445@1|root,COG4445@2|Bacteria,1MVFE@1224|Proteobacteria,439JD@68525|delta/epsilon subdivisions,2X4VZ@28221|Deltaproteobacteria,2YZQ9@29|Myxococcales	28221|Deltaproteobacteria	FJ	tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)	-	-	-	ko:K06169	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MiaE
CMS3_k127_3947098_22	1082931.KKY_2072	9.542e-11	76.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1N4IM@1224|Proteobacteria,2U389@28211|Alphaproteobacteria,3N7XT@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS3_k127_3947098_19	1123242.JH636435_gene1209	3.729e-17	94.0	COG0810@1|root,COG0810@2|Bacteria,2IZYP@203682|Planctomycetes	203682|Planctomycetes	M	carbohydrate binding	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
CMS3_k127_3947098_0	521674.Plim_2928	2.652e-212	683.0	COG0459@1|root,COG0459@2|Bacteria,2IWZS@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_3947098_14	1210884.HG799470_gene14375	7.297e-33	130.0	COG0234@1|root,COG0234@2|Bacteria,2J0E5@203682|Planctomycetes	203682|Planctomycetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_3947098_1	237368.SCABRO_03915	4.787e-206	656.0	COG0459@1|root,COG0459@2|Bacteria,2IXJW@203682|Planctomycetes	203682|Planctomycetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_3947098_3	1121447.JONL01000006_gene223	2.355e-107	359.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2M8Q4@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS3_k127_3947098_16	665942.HMPREF1022_01197	2.222e-25	114.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,2MB0F@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS3_k127_3947098_18	344747.PM8797T_15181	8.037e-23	115.0	COG2331@1|root,COG2331@2|Bacteria,2J0TW@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS3_k127_3947098_10	1122921.KB898191_gene2007	3.871e-51	199.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1UI3P@1239|Firmicutes,4HJMZ@91061|Bacilli,27713@186822|Paenibacillaceae	2|Bacteria	GN	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Cadherin-like,CarboxypepD_reg,Flg_new,Laminin_G_3,PATR,SLH,fn3
CMS3_k127_3947098_12	886293.Sinac_7484	5.588e-43	179.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_3947098_5	886293.Sinac_2761	4.788e-100	344.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_3948745_1	247490.KSU1_B0670	9.06e-106	353.0	COG2255@1|root,COG2255@2|Bacteria,2IXY1@203682|Planctomycetes	203682|Planctomycetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS3_k127_3948745_0	886293.Sinac_5631	5.837e-111	383.0	COG0343@1|root,COG0343@2|Bacteria,2IWXI@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS3_k127_3948745_8	1403819.BATR01000162_gene5382	6.041e-10	71.0	COG2356@1|root,COG2356@2|Bacteria	2|Bacteria	L	deoxyribonuclease I activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHB_HEX_C_1,Calx-beta,Endonuclease_1,LTD
CMS3_k127_3948745_6	246200.SPO1255	2.891e-14	75.0	COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria,4NBJF@97050|Ruegeria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_3948745_7	1293054.HSACCH_00450	2.317e-11	67.0	COG2128@1|root,COG2128@2|Bacteria,1UVG3@1239|Firmicutes	1239|Firmicutes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_3948745_4	391587.KAOT1_03002	2.537e-27	116.0	COG2259@1|root,31BQE@2|Bacteria,4NQH2@976|Bacteroidetes,1I2VX@117743|Flavobacteriia	976|Bacteroidetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS3_k127_3948745_2	1123508.JH636440_gene2102	6.868e-75	269.0	COG3000@1|root,COG3000@2|Bacteria,2J12U@203682|Planctomycetes	203682|Planctomycetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_3948745_9	420662.Mpe_A3813	1.949e-08	63.0	COG0664@1|root,COG0664@2|Bacteria,1RFGF@1224|Proteobacteria,2VR2U@28216|Betaproteobacteria,1KM4V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS3_k127_3948745_3	1485545.JQLW01000005_gene1100	2.327e-45	170.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria	1224|Proteobacteria	G	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS3_k127_3948745_5	1379270.AUXF01000001_gene1944	7.169e-24	114.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CMS3_k127_3993481_0	530564.Psta_2956	4.583e-107	362.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
CMS3_k127_4031122_2	266117.Rxyl_3176	3.275e-64	230.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT,HEAT_2
CMS3_k127_4031122_5	575540.Isop_0175	4.841e-23	115.0	COG1807@1|root,COG1807@2|Bacteria,2J1QR@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4031122_3	234267.Acid_6301	1.218e-61	227.0	COG2227@1|root,COG2227@2|Bacteria,3Y8XU@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_4031122_1	909663.KI867150_gene1728	2.994e-69	248.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,42W8F@68525|delta/epsilon subdivisions,2WRG3@28221|Deltaproteobacteria,2MS12@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_4031122_0	1444309.JAQG01000019_gene564	1.845e-198	631.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,2750X@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_4031122_4	110663.KI911558_gene1184	1.152e-32	146.0	COG0352@1|root,COG0352@2|Bacteria,1G1VB@1117|Cyanobacteria,1GYVT@1129|Synechococcus	1117|Cyanobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.thiE	TMP-TENI
CMS3_k127_4043449_70	1144275.COCOR_00143	9.555e-15	78.0	COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_4043449_67	661478.OP10G_4489	4.917e-16	91.0	2A52F@1|root,30TQU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_75	998674.ATTE01000001_gene3833	5.674e-08	59.0	COG1225@1|root,COG1225@2|Bacteria,1NFDB@1224|Proteobacteria,1SG07@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_4043449_78	1123242.JH636434_gene3351	2.308e-06	61.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_4043449_77	1297742.A176_00134	6.402e-08	66.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4043449_63	1079986.JH164851_gene1149	8.138e-20	100.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_4043449_20	696747.NIES39_C05180	2.042e-93	336.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
CMS3_k127_4043449_72	1205680.CAKO01000037_gene1400	1.606e-10	75.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria,2JTDN@204441|Rhodospirillales	204441|Rhodospirillales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4043449_22	1121405.dsmv_0232	1.813e-91	343.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BS9@68525|delta/epsilon subdivisions,2X733@28221|Deltaproteobacteria,2MPJG@213118|Desulfobacterales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS3_k127_4043449_32	595460.RRSWK_01149	8.264e-52	198.0	COG0631@1|root,COG0631@2|Bacteria,2IZVG@203682|Planctomycetes	203682|Planctomycetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_4043449_33	266117.Rxyl_1053	8.73e-51	187.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	CP_0674	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
CMS3_k127_4043449_29	1033802.SSPSH_001802	1.033e-58	219.0	COG3659@1|root,COG3659@2|Bacteria,1PI63@1224|Proteobacteria,1S9JZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
CMS3_k127_4043449_44	497964.CfE428DRAFT_1236	1.533e-43	172.0	2DDJA@1|root,2ZIAT@2|Bacteria	2|Bacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_4043449_83	1068980.ARVW01000001_gene1360	6.702e-05	52.0	COG4875@1|root,COG4875@2|Bacteria,2IGK4@201174|Actinobacteria,4E4TH@85010|Pseudonocardiales	201174|Actinobacteria	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD,DUF4440
CMS3_k127_4043449_64	1122604.JONR01000009_gene2347	2.114e-19	97.0	COG0671@1|root,COG0671@2|Bacteria,1RFUF@1224|Proteobacteria,1S722@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS3_k127_4043449_55	1173025.GEI7407_2146	1.132e-29	129.0	COG0110@1|root,COG0110@2|Bacteria,1G216@1117|Cyanobacteria,1HAZ5@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS3_k127_4043449_24	497964.CfE428DRAFT_1235	1.409e-82	288.0	COG3239@1|root,COG3239@2|Bacteria	2|Bacteria	I	unsaturated fatty acid biosynthetic process	desA	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS3_k127_4043449_57	1267535.KB906767_gene3867	3.777e-28	120.0	COG4658@1|root,COG4658@2|Bacteria	2|Bacteria	C	electron transport chain	-	-	1.6.5.8	ko:K00347,ko:K03614	-	-	-	-	ko00000,ko01000	-	-	-	Complex1_51K,NQR2_RnfD_RnfE,RnfC_N
CMS3_k127_4043449_45	639030.JHVA01000001_gene1922	1.027e-41	178.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,3Y6YV@57723|Acidobacteria,2JKEW@204432|Acidobacteriia	204432|Acidobacteriia	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_2,TPR_8,UnbV_ASPIC,VCBS
CMS3_k127_4043449_65	483219.LILAB_10755	3.594e-19	104.0	28RWT@1|root,2ZE8Z@2|Bacteria,1P8WG@1224|Proteobacteria,4386A@68525|delta/epsilon subdivisions,2X3G5@28221|Deltaproteobacteria,2YVYF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_41	448385.sce4399	1.691e-44	181.0	COG3239@1|root,COG3239@2|Bacteria,1R8YH@1224|Proteobacteria,4384P@68525|delta/epsilon subdivisions,2X3ER@28221|Deltaproteobacteria,2YVR4@29|Myxococcales	28221|Deltaproteobacteria	I	fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS3_k127_4043449_50	497964.CfE428DRAFT_1239	8.325e-36	158.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_11	1122165.AUHS01000003_gene2189	3.235e-116	402.0	COG0318@1|root,COG0318@2|Bacteria,1PH7B@1224|Proteobacteria,1S1KM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS3_k127_4043449_28	1122165.AUHS01000003_gene2190	4.61e-73	255.0	2DBEV@1|root,2Z8UT@2|Bacteria,1N26S@1224|Proteobacteria,1S0EC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_18	1122165.AUHS01000003_gene2191	3.04e-95	335.0	COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,1RQ8W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	vanA	-	1.14.13.82	ko:K03862	ko00627,ko01120,map00627,map01120	-	R05274	RC00392,RC01533	ko00000,ko00001,ko01000	-	-	-	Rieske
CMS3_k127_4043449_73	504728.K649_11970	6.475e-09	63.0	COG1846@1|root,COG1846@2|Bacteria,1WMZ0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS3_k127_4043449_1	886293.Sinac_0939	1.066e-222	715.0	COG3258@1|root,COG3258@2|Bacteria,2IWXF@203682|Planctomycetes	203682|Planctomycetes	C	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PA14,PSCyt3,PSD2,PSD4,PSD5
CMS3_k127_4043449_4	661478.OP10G_2299	5.019e-178	608.0	COG2960@1|root,COG2960@2|Bacteria	2|Bacteria	M	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_4043449_62	215803.DB30_3195	4.899e-20	102.0	COG2242@1|root,COG2242@2|Bacteria,1QX6B@1224|Proteobacteria,43BYX@68525|delta/epsilon subdivisions,2WSZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_4043449_54	1210884.HG799474_gene15116	1.383e-30	132.0	2EQFW@1|root,33I1X@2|Bacteria,2J1JM@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_76	679935.Alfi_3088	5.905e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,2G33Y@200643|Bacteroidia	976|Bacteroidetes	K	RNA polymerase sigma-70 factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4043449_49	595460.RRSWK_02583	1.599e-37	164.0	COG0457@1|root,COG0793@1|root,COG0845@1|root,COG4995@1|root,COG0457@2|Bacteria,COG0793@2|Bacteria,COG0845@2|Bacteria,COG4995@2|Bacteria,2J07X@203682|Planctomycetes	203682|Planctomycetes	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
CMS3_k127_4043449_38	572480.Arnit_2220	8.674e-46	191.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2YR2T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COGs COG1033 exporter of the RND superfamily protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS3_k127_4043449_47	1219065.VPR01S_08_01040	6.842e-40	160.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XVD7@135623|Vibrionales	135623|Vibrionales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS3_k127_4043449_81	869210.Marky_2097	1.522e-05	58.0	COG4773@1|root,COG4773@2|Bacteria,1WKXU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_51	1394178.AWOO02000002_gene1859	1.204e-34	140.0	COG1309@1|root,COG1309@2|Bacteria,2GJPK@201174|Actinobacteria,4EJG4@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS3_k127_4043449_23	1214242.B446_30205	1.067e-85	295.0	COG0121@1|root,COG0121@2|Bacteria,2GXCD@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4,GATase_6
CMS3_k127_4043449_10	471852.Tcur_0550	1.776e-120	411.0	COG2227@1|root,COG2227@2|Bacteria,2I3C3@201174|Actinobacteria,4ER5A@85012|Streptosporangiales	201174|Actinobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_4043449_25	1496688.ER33_11240	3.603e-81	278.0	COG3000@1|root,COG3000@2|Bacteria,1G441@1117|Cyanobacteria,22T78@167375|Cyanobium	1117|Cyanobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_4043449_9	1403819.BATR01000162_gene5393	3.566e-136	464.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,46WZH@74201|Verrucomicrobia,2IVZE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_39	693986.MOC_1547	1.601e-44	173.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS3_k127_4043449_48	673860.AciM339_1452	1.444e-37	153.0	COG0697@1|root,arCOG00272@2157|Archaea,2Y6Z7@28890|Euryarchaeota,3F2Z3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_4043449_74	388399.SSE37_05040	1.63e-08	66.0	COG0834@1|root,COG0834@2|Bacteria,1RHMR@1224|Proteobacteria,2U942@28211|Alphaproteobacteria	28211|Alphaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_46	266940.Krad_1606	1.851e-41	171.0	COG0840@1|root,COG0840@2|Bacteria,2GP45@201174|Actinobacteria	201174|Actinobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
CMS3_k127_4043449_60	1403819.BATR01000083_gene2435	4.314e-23	105.0	2EANR@1|root,334R8@2|Bacteria,46W9X@74201|Verrucomicrobia,2IURH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4043449_21	1396141.BATP01000023_gene661	2.216e-92	318.0	COG0577@1|root,COG0577@2|Bacteria,46UTH@74201|Verrucomicrobia,2ITTN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_4043449_16	1403819.BATR01000083_gene2433	3.875e-98	343.0	COG4591@1|root,COG4591@2|Bacteria,46UT4@74201|Verrucomicrobia,2IU3C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS3_k127_4043449_27	1403819.BATR01000083_gene2432	1.326e-80	288.0	COG1136@1|root,COG1136@2|Bacteria,46UUF@74201|Verrucomicrobia,2ITZH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_4043449_42	243090.RB4310	2.063e-44	182.0	COG0845@1|root,COG0845@2|Bacteria,2IY6J@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_4043449_68	1384056.N787_02020	6.121e-16	91.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,1S066@1236|Gammaproteobacteria,1X5UB@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_4043449_2	411479.BACUNI_03970	2.926e-204	652.0	COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,2FMH6@200643|Bacteroidia,4ANFX@815|Bacteroidaceae	976|Bacteroidetes	P	COG COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CMS3_k127_4043449_26	489825.LYNGBM3L_73520	4.593e-81	297.0	COG0714@1|root,COG0714@2|Bacteria,1G1CG@1117|Cyanobacteria,1H70V@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4043449_82	367299.JOEE01000001_gene2083	1.792e-05	57.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4FGA2@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4043449_69	463191.SSEG_09999	9.064e-16	93.0	COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria	201174|Actinobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
CMS3_k127_4043449_8	1121859.KB890754_gene773	7.486e-139	456.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,47U3H@768503|Cytophagia	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_4043449_14	595460.RRSWK_02466	1.193e-99	336.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
CMS3_k127_4043449_12	243090.RB13271	5.333e-107	363.0	COG1181@1|root,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_4043449_80	28115.HR11_08690	9.113e-06	60.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
CMS3_k127_4043449_19	287986.DV20_40105	1.693e-93	324.0	COG2234@1|root,COG2234@2|Bacteria,2I9YF@201174|Actinobacteria,4E8GH@85010|Pseudonocardiales	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_4043449_5	1121472.AQWN01000005_gene2370	4.846e-165	534.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,2602C@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CMS3_k127_4043449_56	411468.CLOSCI_01260	1.213e-29	126.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,22054@1506553|Lachnoclostridium	186801|Clostridia	E	COG COG3404 Methenyl tetrahydrofolate cyclohydrolase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
CMS3_k127_4043449_6	1210884.HG799466_gene12501	2.911e-151	509.0	COG0498@1|root,COG0498@2|Bacteria,2IXK6@203682|Planctomycetes	203682|Planctomycetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_4043449_0	1349767.GJA_2681	1.676e-256	822.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,476TQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_4043449_30	1356854.N007_03330	1.129e-56	220.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,4HU4P@91061|Bacilli	91061|Bacilli	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
CMS3_k127_4043449_37	1121918.ARWE01000001_gene249	9.832e-48	187.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,42QDI@68525|delta/epsilon subdivisions,2WJMG@28221|Deltaproteobacteria,43S2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
CMS3_k127_4043449_7	1303518.CCALI_01855	1.974e-141	464.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	glcD	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750	FAD-oxidase_C,FAD_binding_4
CMS3_k127_4043449_59	324602.Caur_1144	1.018e-23	118.0	COG0277@1|root,COG0277@2|Bacteria,2G6FW@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_4043449_15	886293.Sinac_1445	1.077e-98	351.0	COG0247@1|root,COG0247@2|Bacteria,2IXBR@203682|Planctomycetes	203682|Planctomycetes	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
CMS3_k127_4043449_40	215803.DB30_2728	1.643e-44	168.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS3_k127_4043449_34	1121920.AUAU01000004_gene745	4.985e-49	187.0	COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
CMS3_k127_4043449_13	554065.XP_005850866.1	4.163e-102	347.0	COG0042@1|root,KOG2333@2759|Eukaryota,37YV0@33090|Viridiplantae,34K64@3041|Chlorophyta	3041|Chlorophyta	J	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs	-	-	1.3.1.89	ko:K05544	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS3_k127_4043449_36	1379698.RBG1_1C00001G1529	5.401e-48	196.0	COG2304@1|root,COG2304@2|Bacteria,2NPUS@2323|unclassified Bacteria	2|Bacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
CMS3_k127_4043449_79	864051.BurJ1DRAFT_2849	4.187e-06	60.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1MU3S@1224|Proteobacteria,2VZPE@28216|Betaproteobacteria	28216|Betaproteobacteria	M	CARDB domain-containing protein,subtilase family protease	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
CMS3_k127_4043449_61	1131269.AQVV01000011_gene2520	4.796e-22	101.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
CMS3_k127_4043449_71	1380390.JIAT01000012_gene3004	1.605e-13	83.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS3_k127_4043449_52	448385.sce9324	1.378e-33	138.0	COG0746@1|root,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria,42T8X@68525|delta/epsilon subdivisions,2X9X1@28221|Deltaproteobacteria,2YW7C@29|Myxococcales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_4043449_17	313596.RB2501_14804	8.531e-96	329.0	COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1I911@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_4043449_58	572477.Alvin_0466	1.618e-25	121.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1WWKW@135613|Chromatiales	135613|Chromatiales	K	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
CMS3_k127_4043449_31	1304885.AUEY01000016_gene3048	2.47e-53	197.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions,2WMCC@28221|Deltaproteobacteria,2MIZZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_4043449_3	1454004.AW11_01848	1.226e-188	611.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,1KPP6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS3_k127_4069830_6	1117314.PCIT_20239	2.121e-11	70.0	COG3409@1|root,COG3409@2|Bacteria,1RBD0@1224|Proteobacteria,1S2F6@1236|Gammaproteobacteria,2Q4K7@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
CMS3_k127_4069830_4	240016.ABIZ01000001_gene5553	2.763e-13	83.0	COG2911@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS3_k127_4069830_5	1123368.AUIS01000011_gene1139	2.109e-12	80.0	COG1404@1|root,COG1404@2|Bacteria,1R90Q@1224|Proteobacteria,1S01H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS3_k127_4069830_3	886293.Sinac_7484	2.493e-39	155.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4069830_1	886293.Sinac_2761	8.346e-69	268.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_4069830_8	58123.JOFJ01000014_gene5177	0.0005155	53.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS3_k127_4069830_2	903818.KI912268_gene1963	4.365e-43	166.0	COG1720@1|root,COG1720@2|Bacteria,3Y5T1@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
CMS3_k127_4069830_0	1047013.AQSP01000134_gene1354	4.183e-260	830.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_4069830_7	457421.CBFG_04903	6.667e-06	58.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia	186801|Clostridia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
CMS3_k127_4128547_11	314230.DSM3645_11731	5.062e-88	308.0	COG0421@1|root,COG0421@2|Bacteria,2J51Z@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4128547_9	497964.CfE428DRAFT_3779	2.384e-103	378.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N,MIT_C
CMS3_k127_4128547_17	1167006.UWK_00863	4.169e-12	80.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_4128547_3	1254432.SCE1572_37375	1.12e-147	486.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria,2YUFY@29|Myxococcales	28221|Deltaproteobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529,ko:K13530	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
CMS3_k127_4128547_14	502025.Hoch_5558	2.148e-50	194.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,2YVGJ@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
CMS3_k127_4128547_8	671143.DAMO_1866	3.199e-116	396.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4128547_15	526222.Desal_0460	5.197e-29	134.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,43EDC@68525|delta/epsilon subdivisions,2X9DJ@28221|Deltaproteobacteria,2MC0Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS3_k127_4128547_5	1123508.JH636442_gene4210	3.251e-136	448.0	COG0151@1|root,COG0151@2|Bacteria,2IX58@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS3_k127_4128547_10	1303518.CCALI_01616	1.213e-99	334.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_4128547_1	314230.DSM3645_24145	5.544e-227	712.0	COG3119@1|root,COG3119@2|Bacteria,2IXIU@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS3_k127_4128547_6	391598.FBBAL38_09852	1.337e-130	444.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS3_k127_4128547_18	1033991.RLEG12_24520	2.177e-09	71.0	COG2114@1|root,COG2114@2|Bacteria,1QXEH@1224|Proteobacteria,2TX96@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_4128547_2	1123508.JH636443_gene4655	5.241e-218	691.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_4128547_7	443143.GM18_0029	1.229e-117	402.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,43T6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4128547_4	945713.IALB_2638	1.019e-141	470.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_4128547_13	314230.DSM3645_19633	6.697e-57	213.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_4128547_16	1123393.KB891317_gene2320	3.142e-20	99.0	COG1017@1|root,COG1017@2|Bacteria,1RI9P@1224|Proteobacteria	1224|Proteobacteria	C	nitric oxide dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4128547_12	1123368.AUIS01000019_gene1213	1.707e-65	230.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales	225057|Acidithiobacillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_4128547_0	269799.Gmet_3489	6.103e-254	811.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42ZB2@68525|delta/epsilon subdivisions,2WUMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS3_k127_4132590_2	1403819.BATR01000096_gene3117	0.0002478	46.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia,2IUCJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_4132590_1	521393.JH806632_gene967	7.733e-24	106.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4D64E@85005|Actinomycetales	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_4132590_0	497964.CfE428DRAFT_4414	1.578e-36	148.0	COG0321@1|root,COG0321@2|Bacteria,46T11@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS3_k127_4132590_3	448385.sce5399	0.0003231	53.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YWRH@29|Myxococcales	28221|Deltaproteobacteria	L	OB-fold nucleic acid binding domain	-	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS3_k127_4132869_4	886293.Sinac_0803	2.541e-08	65.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_4132869_1	1121472.AQWN01000002_gene2098	3.715e-93	347.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4132869_2	290397.Adeh_0418	5.39e-33	143.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
CMS3_k127_4132869_0	448385.sce3620	4.661e-178	571.0	COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,439ZZ@68525|delta/epsilon subdivisions,2X4EZ@28221|Deltaproteobacteria,2YYW8@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.77,1.2.1.91,3.3.2.12	ko:K02618,ko:K15514	ko00360,ko00362,ko01120,map00360,map00362,map01120	-	R09554,R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS3_k127_4132869_3	522306.CAP2UW1_1842	2.211e-08	67.0	COG0500@1|root,COG2226@2|Bacteria,1Q73B@1224|Proteobacteria,2W6KU@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_4132869_5	1210884.HG799463_gene10101	0.0006342	53.0	COG5126@1|root,COG5126@2|Bacteria,2IZFG@203682|Planctomycetes	203682|Planctomycetes	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_4133825_9	1122939.ATUD01000001_gene577	5.79e-113	407.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4133825_26	521674.Plim_0986	1.128e-21	111.0	COG1595@1|root,COG1595@2|Bacteria,2IZ9U@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_4133825_4	1379270.AUXF01000001_gene1941	9.914e-131	448.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZUHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_4133825_11	1532558.JL39_01715	1.105e-81	280.0	COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,2U1SQ@28211|Alphaproteobacteria,4BAX2@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CMS3_k127_4133825_40	667015.Bacsa_2281	0.0009532	50.0	COG0526@1|root,COG0526@2|Bacteria,4NJ67@976|Bacteroidetes,2FPDG@200643|Bacteroidia,4AMKA@815|Bacteroidaceae	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
CMS3_k127_4133825_41	243090.RB12541	0.0009869	44.0	COG0526@1|root,COG0526@2|Bacteria,2J35Z@203682|Planctomycetes	203682|Planctomycetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CMS3_k127_4133825_5	382464.ABSI01000013_gene1558	3.636e-126	423.0	COG0457@1|root,COG0457@2|Bacteria,46W9Q@74201|Verrucomicrobia,2IVDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4133825_27	1144275.COCOR_01429	3.236e-18	100.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4133825_19	767817.Desgi_4458	2.386e-45	177.0	COG0500@1|root,COG0500@2|Bacteria,1UTAX@1239|Firmicutes,2527A@186801|Clostridia	186801|Clostridia	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4133825_16	767817.Desgi_2658	1.883e-56	222.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,260SX@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_4133825_20	748449.Halha_1790	1.024e-44	181.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3WAE1@53433|Halanaerobiales	186801|Clostridia	NU	PFAM Type II IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_4133825_23	765952.PUV_03760	8.237e-38	163.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,2JFR7@204428|Chlamydiae	204428|Chlamydiae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
CMS3_k127_4133825_33	1114856.C496_15537	1.407e-12	77.0	COG0596@1|root,arCOG01648@2157|Archaea,2XV9I@28890|Euryarchaeota,23TT2@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS3_k127_4133825_30	530564.Psta_2415	1.547e-14	81.0	COG0457@1|root,COG0457@2|Bacteria,2J0VX@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4133825_14	485913.Krac_4654	1.517e-67	242.0	COG0483@1|root,COG0483@2|Bacteria,2G88V@200795|Chloroflexi	200795|Chloroflexi	G	inositol monophosphate 1-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4133825_22	391625.PPSIR1_30923	7.051e-41	158.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria	1224|Proteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_0052,iEcSMS35_1347.EcSMS35_0053,iJN746.PP_0399,iSDY_1059.SDY_0074	Metallophos
CMS3_k127_4133825_6	986075.CathTA2_2353	8.442e-125	412.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli	91061|Bacilli	C	Belongs to the citrate synthase family	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_4133825_13	1121406.JAEX01000001_gene32	3.891e-69	251.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2M8KS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS3_k127_4133825_17	1260251.SPISAL_06715	6.831e-55	222.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales	135613|Chromatiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS3_k127_4133825_36	1165841.SULAR_03257	1.01e-10	75.0	2BXI0@1|root,2Z9A2@2|Bacteria,1R9XN@1224|Proteobacteria,43BG2@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF2459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
CMS3_k127_4133825_1	671143.DAMO_3028	1.96e-167	537.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	egtB	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
CMS3_k127_4133825_18	656519.Halsa_2243	2.758e-46	178.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WAAI@53433|Halanaerobiales	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS3_k127_4133825_38	66377.JOBH01000013_gene1885	8.285e-07	61.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GJ09@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
CMS3_k127_4133825_39	1347392.CCEZ01000025_gene3222	0.0002814	54.0	COG1918@1|root,COG1918@2|Bacteria,1VMJD@1239|Firmicutes,24VI7@186801|Clostridia,36U3G@31979|Clostridiaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS3_k127_4133825_2	1125863.JAFN01000001_gene2640	6.4e-164	546.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS3_k127_4133825_15	324057.Pjdr2_2682	1.643e-57	211.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,26QCU@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS3_k127_4133825_32	28072.Nos7524_3722	6.293e-13	76.0	COG2062@1|root,COG2062@2|Bacteria,1G6QD@1117|Cyanobacteria,1HN53@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM Phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS3_k127_4133825_29	215803.DB30_8034	2.547e-15	91.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4133825_35	448385.sce1844	2.566e-11	78.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_4133825_34	247156.NFA_51460	7.916e-12	74.0	COG3832@1|root,COG3832@2|Bacteria,2IMM4@201174|Actinobacteria,4G1DE@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_4133825_0	243090.RB607	5.631e-175	567.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_4133825_8	886293.Sinac_7047	3.299e-117	387.0	COG3828@1|root,COG3828@2|Bacteria,2IY8Q@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS3_k127_4133825_10	1348657.M622_08980	3.908e-107	359.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,2WFJ1@28216|Betaproteobacteria,2KVGN@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CMS3_k127_4133825_24	1000565.METUNv1_00933	3.381e-26	115.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2VQUA@28216|Betaproteobacteria,2KXH3@206389|Rhodocyclales	206389|Rhodocyclales	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
CMS3_k127_4133825_21	1125863.JAFN01000001_gene1790	2.186e-44	179.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_4133825_37	1068978.AMETH_2201	4.086e-08	66.0	COG4932@1|root,COG4932@2|Bacteria,2IPQA@201174|Actinobacteria,4E4F7@85010|Pseudonocardiales	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4133825_25	929562.Emtol_0534	3.88e-22	105.0	2AN5I@1|root,31D3D@2|Bacteria,4NQTI@976|Bacteroidetes,47QVV@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4920)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4920
CMS3_k127_4133825_7	1408433.JHXV01000002_gene442	4.933e-120	422.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS3_k127_4133825_28	443143.GM18_0922	3.639e-17	90.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
CMS3_k127_4133825_12	880073.Calab_3613	3.651e-81	282.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944	-	ko:K00412,ko:K02635,ko:K02637,ko:K03887,ko:K03891,ko:K15879	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
CMS3_k127_4133825_3	290397.Adeh_1764	6.482e-147	478.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WKEK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
CMS3_k127_4147105_5	42256.RradSPS_0757	5.267e-05	56.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_4147105_0	1499967.BAYZ01000170_gene5483	2.092e-77	289.0	COG0612@1|root,COG0612@2|Bacteria,2NP5H@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_4147105_1	1499967.BAYZ01000170_gene5483	3.53e-77	286.0	COG0612@1|root,COG0612@2|Bacteria,2NP5H@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_4147105_2	575540.Isop_2753	5.786e-62	236.0	COG1187@1|root,COG1187@2|Bacteria,2IYUS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_4147105_3	886293.Sinac_2015	2.098e-56	208.0	COG1482@1|root,COG1482@2|Bacteria,2IZ3A@203682|Planctomycetes	203682|Planctomycetes	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS3_k127_4147105_4	452637.Oter_4112	1.077e-09	69.0	2C85M@1|root,334CZ@2|Bacteria,46WIF@74201|Verrucomicrobia,3K9X3@414999|Opitutae	414999|Opitutae	S	PFAM Stress responsive alpha-beta barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS3_k127_4148795_0	204669.Acid345_2310	2.889e-95	320.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_4148795_3	1384054.N790_01735	4.235e-37	154.0	COG0346@1|root,COG0346@2|Bacteria,1NB98@1224|Proteobacteria,1SS2K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS3_k127_4148795_4	1198452.Jab_2c32600	1.133e-28	132.0	COG2207@1|root,COG2207@2|Bacteria,1R4RI@1224|Proteobacteria,2VXT1@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS3_k127_4148795_6	649639.Bcell_3474	0.0002965	53.0	COG1595@1|root,COG1595@2|Bacteria,1V8GV@1239|Firmicutes,4HHRC@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4148795_2	1210884.HG799471_gene14563	5.237e-63	245.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4148795_1	696747.NIES39_C05180	4.148e-70	263.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
CMS3_k127_4148795_5	1123508.JH636439_gene1181	1.299e-27	117.0	COG3293@1|root,COG4447@1|root,COG3293@2|Bacteria,COG4447@2|Bacteria,2IXU6@203682|Planctomycetes	203682|Planctomycetes	L	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4163906_1	204669.Acid345_1385	1.803e-112	375.0	COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
CMS3_k127_4163906_0	204669.Acid345_1384	2.086e-162	518.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_4181226_1	595460.RRSWK_01927	2.266e-07	64.0	COG1595@1|root,COG1595@2|Bacteria,2J02A@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_4181226_0	1123508.JH636449_gene7349	2.642e-29	136.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_419212_13	497964.CfE428DRAFT_0326	1.335e-74	274.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS3_k127_419212_22	1123070.KB899258_gene1926	2.953e-35	155.0	COG0560@1|root,COG0560@2|Bacteria,46XX1@74201|Verrucomicrobia,2IUCC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS3_k127_419212_3	1267005.KB911257_gene1130	2.826e-122	410.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U1NZ@28211|Alphaproteobacteria,3N9J7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058,ko:K03778	ko00260,ko00620,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00620,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00704,R00717,R01388,R01513	RC00031,RC00042,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS3_k127_419212_5	1125863.JAFN01000001_gene473	1.407e-103	353.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS3_k127_419212_28	1122933.JNIY01000003_gene1020	7.002e-15	81.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4F2QP@85016|Cellulomonadaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS3_k127_419212_27	1123070.KB899256_gene2162	9.3e-16	84.0	COG1862@1|root,COG1862@2|Bacteria,46T88@74201|Verrucomicrobia,2IUY8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS3_k127_419212_24	269796.Rru_A2350	2.159e-25	117.0	COG0500@1|root,COG0500@2|Bacteria,1RD3W@1224|Proteobacteria,2UH9K@28211|Alphaproteobacteria,2JUF7@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_419212_7	530564.Psta_4206	8.707e-84	296.0	COG0482@1|root,COG0482@2|Bacteria,2IXFF@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS3_k127_419212_25	1123070.KB899254_gene1170	1.01e-24	106.0	COG0776@1|root,COG0776@2|Bacteria,46T4R@74201|Verrucomicrobia,2IUNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_419212_34	1469607.KK073768_gene3116	0.0005039	52.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1HMQH@1161|Nostocales	1117|Cyanobacteria	CT	HEAT repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CMS3_k127_419212_33	756272.Plabr_2203	0.0004205	51.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS3_k127_419212_0	1519464.HY22_00255	0.0	1106.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_419212_19	234267.Acid_6726	5.953e-36	156.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_419212_30	1121448.DGI_0380	1.312e-07	64.0	COG0737@1|root,COG0737@2|Bacteria,1NDBC@1224|Proteobacteria,42V2W@68525|delta/epsilon subdivisions,2X5T9@28221|Deltaproteobacteria,2MBXJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_419212_4	247490.KSU1_C0199	3.347e-107	366.0	COG0621@1|root,COG0621@2|Bacteria,2IX1E@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_419212_8	314230.DSM3645_11472	1.731e-83	290.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2IX5J@203682|Planctomycetes	203682|Planctomycetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS3_k127_419212_9	391625.PPSIR1_31883	2.035e-82	284.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
CMS3_k127_419212_15	592029.DDD_3155	9.938e-65	237.0	COG3424@1|root,COG3424@2|Bacteria,4NDZU@976|Bacteroidetes,1HX2P@117743|Flavobacteriia,3HJQ1@363408|Nonlabens	976|Bacteroidetes	Q	Chalcone and stilbene synthases, N-terminal domain	bcsA	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N,FAE1_CUT1_RppA
CMS3_k127_419212_20	105420.BBPO01000031_gene6601	1.895e-35	153.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria,2NIEI@228398|Streptacidiphilus	201174|Actinobacteria	S	Phospholipid methyltransferase	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
CMS3_k127_419212_26	404589.Anae109_4182	9.718e-21	107.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	srsC	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
CMS3_k127_419212_21	1123242.JH636438_gene5771	2.926e-35	155.0	COG2706@1|root,COG2706@2|Bacteria,2J55E@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_419212_14	886293.Sinac_6514	7.535e-68	245.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
CMS3_k127_419212_2	1382306.JNIM01000001_gene466	3.079e-188	611.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_419212_29	547163.BN979_03283	5.169e-10	70.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,233XD@1762|Mycobacteriaceae	201174|Actinobacteria	S	acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
CMS3_k127_419212_32	1121033.AUCF01000017_gene3758	2.966e-05	57.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,2JY59@204441|Rhodospirillales	28211|Alphaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_419212_12	886293.Sinac_7456	3.188e-76	266.0	COG0142@1|root,COG0142@2|Bacteria,2IX56@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_419212_1	237368.SCABRO_01252	2.864e-190	613.0	COG1154@1|root,COG1154@2|Bacteria,2IYHC@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS3_k127_419212_17	243231.GSU2065	2.283e-42	168.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS3_k127_419212_11	478741.JAFS01000001_gene1901	7.635e-78	278.0	COG1249@1|root,COG1249@2|Bacteria,46S8I@74201|Verrucomicrobia,37GDC@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_419212_6	7425.NV17547-PA	3.677e-94	337.0	COG4581@1|root,KOG0948@2759|Eukaryota,38Y04@33154|Opisthokonta,3BBAD@33208|Metazoa,3CRCJ@33213|Bilateria,41U3Z@6656|Arthropoda,3SHVS@50557|Insecta,46H6Y@7399|Hymenoptera	33208|Metazoa	A	DSHCT	SKIV2L2	GO:0000375,GO:0000377,GO:0000398,GO:0000460,GO:0002252,GO:0002376,GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0008380,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0022613,GO:0031499,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042623,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0070013,GO:0070035,GO:0071013,GO:0071704,GO:0071840,GO:0090304,GO:0098542,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1990904	3.6.4.13	ko:K12598	ko03018,map03018	M00393	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016,ko03019,ko03041	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
CMS3_k127_419212_16	1242864.D187_003153	1.246e-42	182.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	stk1	-	2.7.11.1	ko:K08282,ko:K08884,ko:K11916,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko02044	-	-	-	DUF4384,FGE-sulfatase,Pkinase
CMS3_k127_419212_23	1210884.HG799464_gene10657	1.413e-30	139.0	COG0631@1|root,COG0631@2|Bacteria,2IWWV@203682|Planctomycetes	203682|Planctomycetes	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS3_k127_419212_10	521674.Plim_0407	6.153e-82	288.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_419212_18	404589.Anae109_1855	2.945e-38	161.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_4209998_1	880073.Calab_3353	7.415e-55	220.0	COG1785@1|root,COG1785@2|Bacteria,2NPNF@2323|unclassified Bacteria	2|Bacteria	P	Alkaline phosphatase homologues	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CMS3_k127_4209998_2	1121920.AUAU01000019_gene2602	2.046e-28	127.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria	57723|Acidobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS3_k127_4209998_0	697282.Mettu_2036	2.082e-79	292.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria,1XENI@135618|Methylococcales	135618|Methylococcales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4209998_3	224324.aq_1263	5.052e-22	110.0	COG4659@1|root,COG4659@2|Bacteria,2G4YT@200783|Aquificae	200783|Aquificae	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
CMS3_k127_4232571_0	1110697.NCAST_08_00260	3.187e-63	231.0	COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria,4FXD4@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CMS3_k127_4232571_1	891968.Anamo_1965	2.363e-44	174.0	COG1113@1|root,COG1113@2|Bacteria	2|Bacteria	E	amino acid transport	-	-	-	ko:K03294,ko:K11737	-	-	-	-	ko00000,ko02000	2.A.3.1.7,2.A.3.2	-	-	AA_permease,AA_permease_2
CMS3_k127_4255639_7	756272.Plabr_2435	2.399e-30	139.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159,Prenyltrans
CMS3_k127_4255639_5	1385935.N836_16210	4.493e-35	155.0	2C57D@1|root,2Z7RS@2|Bacteria,1G44D@1117|Cyanobacteria,1HA50@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
CMS3_k127_4255639_2	264198.Reut_B3680	1.256e-54	210.0	COG4257@1|root,COG4257@2|Bacteria,1R448@1224|Proteobacteria,2W139@28216|Betaproteobacteria,1KEAH@119060|Burkholderiaceae	28216|Betaproteobacteria	V	Carboxypeptidase regulatory-like domain	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg
CMS3_k127_4255639_0	1121904.ARBP01000005_gene4755	8.725e-234	736.0	COG1858@1|root,COG1858@2|Bacteria,4NJ4X@976|Bacteroidetes	976|Bacteroidetes	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4255639_8	1121378.KB899707_gene1417	5.902e-26	115.0	COG3059@1|root,COG3059@2|Bacteria,1WMV5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4255639_4	269482.Bcep1808_4060	3.362e-42	164.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2WEB3@28216|Betaproteobacteria,1KFV4@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4255639_6	395495.Lcho_0902	4.877e-35	153.0	COG3852@1|root,COG4585@1|root,COG3852@2|Bacteria,COG4585@2|Bacteria,1R43J@1224|Proteobacteria,2VPEB@28216|Betaproteobacteria,1KMD2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
CMS3_k127_4255639_3	765913.ThidrDRAFT_1194	4.142e-53	209.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,1RZ37@1236|Gammaproteobacteria,1WX58@135613|Chromatiales	135613|Chromatiales	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS3_k127_4255639_9	1500301.JQMF01000007_gene1483	5.741e-06	59.0	COG4249@1|root,COG4249@2|Bacteria,1R3SZ@1224|Proteobacteria,2TVR0@28211|Alphaproteobacteria,4B96N@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Caspase domain	MA20_39250	-	-	-	-	-	-	-	-	-	-	-	Lectin_C,PG_binding_1,Peptidase_C14
CMS3_k127_4255639_1	391598.FBBAL38_09852	3.919e-126	428.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS3_k127_4273236_10	857087.Metme_3890	5.472e-16	81.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_4273236_11	1278073.MYSTI_07947	1.45e-10	69.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4273236_5	926550.CLDAP_02300	1.595e-41	175.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi	200795|Chloroflexi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4273236_6	56110.Oscil6304_1374	7.756e-35	152.0	2DBHM@1|root,2Z9AY@2|Bacteria,1G396@1117|Cyanobacteria,1H9MI@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4273236_8	290397.Adeh_3735	1.113e-20	101.0	COG1595@1|root,COG1595@2|Bacteria,1PEZT@1224|Proteobacteria,42W2J@68525|delta/epsilon subdivisions,2WS5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4273236_2	530564.Psta_4044	6.407e-49	201.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4273236_0	491205.JARQ01000006_gene2674	1.59e-57	218.0	COG2304@1|root,COG2304@2|Bacteria,4NIM2@976|Bacteroidetes	976|Bacteroidetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS3_k127_4273236_9	357804.Ping_3341	1.657e-19	100.0	COG0614@1|root,COG0614@2|Bacteria,1QIB8@1224|Proteobacteria,1TG5G@1236|Gammaproteobacteria,2QHGW@267894|Psychromonadaceae	1236|Gammaproteobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_4273236_3	1203190.CAJP01000044_gene1959	2.049e-45	190.0	COG0609@1|root,COG0609@2|Bacteria,2GK8Z@201174|Actinobacteria,22JSE@1653|Corynebacteriaceae	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS3_k127_4273236_1	1293047.CBMA010000033_gene2209	7.324e-53	208.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,23SRW@183963|Halobacteria	183963|Halobacteria	E	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	btuD	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS3_k127_4273236_7	1123228.AUIH01000008_gene2428	3.543e-30	137.0	COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_4273236_4	867845.KI911784_gene1605	7.201e-45	183.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	CARDB,DUF4091,FlgD_ig,Laminin_G_3,PKD,Peptidase_M43
CMS3_k127_4293094_0	1385520.N802_16465	8.304e-130	431.0	COG3550@1|root,COG3550@2|Bacteria,2IH7C@201174|Actinobacteria,4FIBJ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
CMS3_k127_4293094_1	290399.Arth_3973	5.215e-13	74.0	2DDJR@1|root,2ZIC6@2|Bacteria,2I5B2@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
CMS3_k127_4298070_5	1121468.AUBR01000029_gene1565	6.535e-57	211.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,42F98@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS3_k127_4298070_9	653733.Selin_0539	1.543e-39	156.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462,ko:K07391	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS3_k127_4298070_11	497964.CfE428DRAFT_3476	7.21e-33	149.0	COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS3_k127_4298070_13	1410661.JNKW01000001_gene577	3.997e-12	70.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS3_k127_4298070_6	575540.Isop_1648	1.083e-49	196.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_4298070_1	1123508.JH636443_gene5095	2.73e-205	681.0	COG1197@1|root,COG1197@2|Bacteria,2IWV4@203682|Planctomycetes	203682|Planctomycetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS3_k127_4298070_8	1238182.C882_3823	1.144e-39	171.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,2JSAS@204441|Rhodospirillales	204441|Rhodospirillales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS3_k127_4298070_0	1191523.MROS_2197	7.079e-211	676.0	COG1217@1|root,COG1217@2|Bacteria	2|Bacteria	T	GTPase activity	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_4298070_4	1158294.JOMI01000009_gene1294	4.809e-60	224.0	COG1047@1|root,COG1047@2|Bacteria,4NKSZ@976|Bacteroidetes,2FSA7@200643|Bacteroidia	976|Bacteroidetes	O	Protein of unknown function (DUF4026)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314,DUF4026
CMS3_k127_4298070_14	314278.NB231_15063	6.107e-06	54.0	2EB0T@1|root,3351P@2|Bacteria,1NCHM@1224|Proteobacteria,1SJ6Z@1236|Gammaproteobacteria,1X1WX@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4298070_2	383372.Rcas_1223	7.239e-93	315.0	COG1092@1|root,COG1092@2|Bacteria,2G7FC@200795|Chloroflexi,376DP@32061|Chloroflexia	32061|Chloroflexia	J	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS3_k127_4298070_10	317655.Sala_3052	3.958e-34	143.0	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,2UAE3@28211|Alphaproteobacteria,2K689@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_4298070_12	215803.DB30_4543	5.942e-14	85.0	COG1051@1|root,COG1051@2|Bacteria,1NDF2@1224|Proteobacteria,439V0@68525|delta/epsilon subdivisions,2X58Q@28221|Deltaproteobacteria,2Z09R@29|Myxococcales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_4298070_7	290397.Adeh_1709	1.126e-45	191.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUMV@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4298070_3	292459.STH3278	6.213e-74	258.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS3_k127_4313081_0	521674.Plim_0363	1.037e-93	315.0	COG2133@1|root,COG2133@2|Bacteria,2IXAF@203682|Planctomycetes	203682|Planctomycetes	G	glucose sorbosone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	DUF1080,GSDH,SGL
CMS3_k127_4313081_2	324602.Caur_0649	2.586e-41	170.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_4313081_3	1463895.JODA01000010_gene7017	4.594e-23	115.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
CMS3_k127_4313081_4	68170.KL590515_gene733	3.091e-05	55.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4E9XU@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_4313081_1	338966.Ppro_3327	8.763e-58	213.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42QTI@68525|delta/epsilon subdivisions,2WMRH@28221|Deltaproteobacteria,43SYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_4361852_3	547559.Nmag_2859	0.0007433	52.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota,23SIB@183963|Halobacteria	183963|Halobacteria	C	COG1413 FOG HEAT repeat	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_4361852_2	877418.ATWV01000011_gene79	5.62e-08	66.0	COG3408@1|root,COG3408@2|Bacteria,2J5J1@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Trehalase	-	-	-	-	-	-	-	-	-	-	-	-	Trehalase
CMS3_k127_4361852_1	713586.KB900536_gene151	8.33e-100	334.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RPGU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_4361852_0	1121930.AQXG01000011_gene1759	1.701e-130	434.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_4402800_1	945713.IALB_0608	1.469e-80	285.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CMS3_k127_4402800_0	945713.IALB_0608	1.987e-134	458.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CMS3_k127_4402800_6	589865.DaAHT2_0560	2.014e-06	51.0	COG3526@1|root,COG3526@2|Bacteria,1PSK4@1224|Proteobacteria,433FM@68525|delta/epsilon subdivisions,2WX6C@28221|Deltaproteobacteria,2MP5Z@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
CMS3_k127_4402800_5	382464.ABSI01000011_gene2473	8.055e-09	67.0	COG0028@1|root,COG1404@1|root,COG2885@1|root,COG3210@1|root,COG3291@1|root,COG3391@1|root,COG3507@1|root,COG4733@1|root,COG4935@1|root,COG5295@1|root,COG0028@2|Bacteria,COG1404@2|Bacteria,COG2885@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3507@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5295@2|Bacteria,46W6Z@74201|Verrucomicrobia	2|Bacteria	GMOU	Fibronectin type 3 domain	-	-	3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3	ko:K01179,ko:K01361,ko:K01637,ko:K01729,ko:K09942,ko:K20276	ko00051,ko00500,ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00051,map00500,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479,R03706,R06200,R11307,R11308	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH5,GH9	-	fn3
CMS3_k127_4402800_4	1123392.AQWL01000004_gene2852	3.856e-21	103.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,1KRRY@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Type III pantothenate kinase	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS3_k127_4402800_2	1340493.JNIF01000003_gene2233	5.132e-58	208.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_4402800_3	1340493.JNIF01000003_gene2232	1.004e-39	162.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_4430044_6	1235279.C772_02835	9.294e-15	85.0	COG1721@1|root,COG1721@2|Bacteria,1V2UW@1239|Firmicutes,4HCUR@91061|Bacilli,26EBW@186818|Planococcaceae	91061|Bacilli	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4430044_3	1069080.KB913028_gene470	8.92e-54	200.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4H2KT@909932|Negativicutes	909932|Negativicutes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS3_k127_4430044_1	1121930.AQXG01000004_gene2997	2.932e-97	327.0	COG0413@1|root,COG0413@2|Bacteria,4NDX4@976|Bacteroidetes,1IRN1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS3_k127_4430044_2	1297742.A176_06744	1.389e-78	288.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
CMS3_k127_4430044_4	266264.Rmet_5187	3.48e-51	201.0	COG2911@1|root,COG3055@1|root,COG2911@2|Bacteria,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,2VX2F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_4,fn3
CMS3_k127_4430044_0	1122182.KB903816_gene1654	6.842e-117	389.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DABI@85008|Micromonosporales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
CMS3_k127_4430044_5	530564.Psta_0474	3.416e-44	166.0	COG0691@1|root,COG0691@2|Bacteria,2IZPN@203682|Planctomycetes	203682|Planctomycetes	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS3_k127_4442426_13	1121904.ARBP01000001_gene5637	6.329e-86	294.0	COG2035@1|root,COG2035@2|Bacteria,4NFKI@976|Bacteroidetes,47MKT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
CMS3_k127_4442426_27	760192.Halhy_4422	1.162e-66	247.0	COG4927@1|root,COG4927@2|Bacteria,4NGJT@976|Bacteroidetes	976|Bacteroidetes	S	PFAM peptidase C45 acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_4442426_7	1123354.AUDR01000018_gene1126	4.692e-103	352.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KRXA@119069|Hydrogenophilales	119069|Hydrogenophilales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS3_k127_4442426_28	118166.JH976537_gene3267	1.88e-66	234.0	COG2738@1|root,COG2738@2|Bacteria,1G0UU@1117|Cyanobacteria,1HA9R@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS3_k127_4442426_17	1173022.Cri9333_1305	2.76e-79	272.0	COG0605@1|root,COG0605@2|Bacteria,1G0N2@1117|Cyanobacteria,1H8FH@1150|Oscillatoriales	1117|Cyanobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS3_k127_4442426_62	1313172.YM304_42760	0.0001471	52.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4442426_29	1382306.JNIM01000001_gene1022	6.859e-62	217.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS3_k127_4442426_1	1382306.JNIM01000001_gene1023	5.682e-273	864.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_4442426_11	1382306.JNIM01000001_gene1024	1.635e-88	329.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS3_k127_4442426_61	1123508.JH636445_gene6839	7.327e-05	51.0	COG0858@1|root,COG0858@2|Bacteria,2J19A@203682|Planctomycetes	203682|Planctomycetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4442426_18	443144.GM21_0067	3.349e-79	282.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-3	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_4442426_16	1499967.BAYZ01000014_gene6372	7.786e-80	282.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_4442426_42	1122138.AQUZ01000023_gene7903	1.634e-34	143.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2I52Z@201174|Actinobacteria,4DWNT@85009|Propionibacteriales	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF,GAF_2
CMS3_k127_4442426_59	1131269.AQVV01000032_gene310	8.293e-08	64.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS3_k127_4442426_30	395961.Cyan7425_0803	1.259e-56	209.0	COG3145@1|root,COG3145@2|Bacteria,1G503@1117|Cyanobacteria	1117|Cyanobacteria	L	Alkylated DNA repair protein	alkB	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
CMS3_k127_4442426_26	1254432.SCE1572_18550	5.192e-67	260.0	COG4284@1|root,COG4284@2|Bacteria,1Q5YI@1224|Proteobacteria,42QK5@68525|delta/epsilon subdivisions,2WKKW@28221|Deltaproteobacteria,2YVJD@29|Myxococcales	28221|Deltaproteobacteria	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS3_k127_4442426_8	1255043.TVNIR_3702	1.432e-101	357.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,1WW2Y@135613|Chromatiales	135613|Chromatiales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS3_k127_4442426_41	1121472.AQWN01000002_gene2108	1.07e-34	152.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
CMS3_k127_4442426_52	1121957.ATVL01000012_gene633	2.913e-20	108.0	COG5662@1|root,COG5662@2|Bacteria,4P3CI@976|Bacteroidetes,47UWT@768503|Cytophagia	976|Bacteroidetes	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS3_k127_4442426_24	1443111.JASG01000004_gene568	1.708e-69	266.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3ZWQR@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
CMS3_k127_4442426_54	1089550.ATTH01000001_gene1014	6.958e-17	96.0	COG0699@1|root,COG1520@1|root,COG0699@2|Bacteria,COG1520@2|Bacteria,4PHXE@976|Bacteroidetes,1FKAD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4442426_63	298655.KI912266_gene1638	0.0002217	55.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TIR_2,WD40
CMS3_k127_4442426_57	96561.Dole_0621	2.854e-11	73.0	COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,42T2B@68525|delta/epsilon subdivisions,2WPEV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS3_k127_4442426_33	1353537.TP2_00590	1.702e-43	182.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U22Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	GAF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
CMS3_k127_4442426_25	156889.Mmc1_2198	2.933e-69	263.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2U0H8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidase, M50 family	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2
CMS3_k127_4442426_5	247490.KSU1_C0857	8.608e-119	392.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4442426_19	1313304.CALK_0284	1.94e-76	281.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4442426_53	502025.Hoch_0521	3.306e-18	99.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4442426_46	518766.Rmar_0442	1.165e-31	144.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1FIMW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CMS3_k127_4442426_39	237368.SCABRO_01883	2.171e-35	156.0	COG2304@1|root,COG2304@2|Bacteria,2IYZ1@203682|Planctomycetes	203682|Planctomycetes	A	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
CMS3_k127_4442426_64	886293.Sinac_5516	0.0002777	55.0	COG0457@1|root,COG0457@2|Bacteria,2J1FF@203682|Planctomycetes	203682|Planctomycetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS3_k127_4442426_60	1211114.ALIP01000002_gene534	3.734e-07	64.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,1RMD3@1236|Gammaproteobacteria,1X36E@135614|Xanthomonadales	135614|Xanthomonadales	S	von willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA_2
CMS3_k127_4442426_43	316056.RPC_1443	7.68e-34	141.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,3JRSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS3_k127_4442426_37	1168065.DOK_06205	9.862e-39	161.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1J6D7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	HAD-hyrolase-like	gph	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_3372,iSbBS512_1146.SbBS512_E3762,iYL1228.KPN_03756	HAD_2
CMS3_k127_4442426_45	1434929.X946_5059	3.392e-32	138.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,2VHT7@28216|Betaproteobacteria,1K0NU@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Transport permease protein	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS3_k127_4442426_14	671143.DAMO_0252	1.152e-84	310.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.38	ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS3_k127_4442426_35	671143.DAMO_0249	5.869e-40	171.0	COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_4442426_23	1265502.KB905942_gene2833	1.365e-69	250.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,2VV87@28216|Betaproteobacteria,4AFMD@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2
CMS3_k127_4442426_31	671143.DAMO_0292	6.358e-55	209.0	COG0438@1|root,COG3064@1|root,COG0438@2|Bacteria,COG3064@2|Bacteria,2NR6D@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Radical_SAM,SPASM
CMS3_k127_4442426_56	765913.ThidrDRAFT_0138	1.648e-14	83.0	COG1216@1|root,COG2120@1|root,COG1216@2|Bacteria,COG2120@2|Bacteria,1R4JR@1224|Proteobacteria,1RZTQ@1236|Gammaproteobacteria,1X2DW@135613|Chromatiales	135613|Chromatiales	M	PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS3_k127_4442426_48	1380408.AVGH01000033_gene481	6.158e-28	130.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli	91061|Bacilli	S	glycosyl transferase family 2	galnac-T15	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
CMS3_k127_4442426_36	1356852.N008_00915	6.496e-40	157.0	29X2B@1|root,30IQT@2|Bacteria,4P7IX@976|Bacteroidetes,47WTX@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4442426_50	1267533.KB906733_gene3471	2.817e-26	127.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
CMS3_k127_4442426_32	1089551.KE386572_gene1226	2.407e-50	193.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS3_k127_4442426_51	266117.Rxyl_3119	3.065e-23	111.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4CQMB@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4442426_38	671143.DAMO_0292	3.461e-37	161.0	COG0438@1|root,COG3064@1|root,COG0438@2|Bacteria,COG3064@2|Bacteria,2NR6D@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Radical_SAM,SPASM
CMS3_k127_4442426_58	96561.Dole_2414	6.498e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MPUH@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_2,TPR_7,TPR_8
CMS3_k127_4442426_34	1191523.MROS_0012	4.817e-41	168.0	COG1158@1|root,COG1158@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS3_k127_4442426_40	1416759.AYMR01000002_gene1833	7.768e-35	144.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4FNR9@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
CMS3_k127_4442426_47	237368.SCABRO_03475	8.855e-31	136.0	COG0805@1|root,COG0805@2|Bacteria,2IZ9K@203682|Planctomycetes	203682|Planctomycetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS3_k127_4442426_22	575540.Isop_1086	1.056e-72	273.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,2IXHK@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS3_k127_4442426_0	1301098.PKB_3948	0.0	1247.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,1RSNV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	helicase	lhr	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,HTH_42,Helicase_C
CMS3_k127_4442426_3	1121377.KB906402_gene3206	1.332e-137	445.0	COG1064@1|root,COG1064@2|Bacteria	2|Bacteria	P	alcohol dehydrogenase	adh	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_4442426_2	1232410.KI421424_gene1814	8.256e-156	513.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,43CGH@68525|delta/epsilon subdivisions,2WJ3J@28221|Deltaproteobacteria,43TNM@69541|Desulfuromonadales	28221|Deltaproteobacteria	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS3_k127_4442426_4	1125863.JAFN01000001_gene1835	5.895e-128	431.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS3_k127_4442426_21	344747.PM8797T_20014	2.424e-73	273.0	COG0020@1|root,COG0020@2|Bacteria,2IX6Z@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS3_k127_4442426_44	457570.Nther_1434	1.98e-32	137.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia	186801|Clostridia	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS3_k127_4442426_15	595460.RRSWK_03690	1.029e-82	297.0	COG1702@1|root,COG1702@2|Bacteria,2IXBB@203682|Planctomycetes	203682|Planctomycetes	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS3_k127_4442426_55	1120972.AUMH01000001_gene1261	3.405e-15	88.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,279W9@186823|Alicyclobacillaceae	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS3_k127_4442426_49	1142394.PSMK_22790	7.715e-28	127.0	COG1191@1|root,COG1191@2|Bacteria,2IX9S@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_4442426_6	573370.DMR_21290	1.806e-107	362.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2M9PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS3_k127_4442426_9	290397.Adeh_2667	8.284e-100	354.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Pyr_redox_3
CMS3_k127_4442426_12	694427.Palpr_0869	4.814e-86	311.0	COG0484@1|root,COG0484@2|Bacteria,4P0AH@976|Bacteroidetes,2FYI2@200643|Bacteroidia	976|Bacteroidetes	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4442426_20	1408473.JHXO01000005_gene1865	2.696e-76	270.0	COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes,2FXKU@200643|Bacteroidia	976|Bacteroidetes	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4442426_65	36809.MAB_4674c	0.0009024	51.0	COG0822@1|root,COG0822@2|Bacteria,2H0PK@201174|Actinobacteria,23DWQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS3_k127_4442426_10	1254432.SCE1572_15930	3.247e-93	331.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
CMS3_k127_4444789_0	391603.FBALC1_04702	5.326e-13	81.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,PKD
CMS3_k127_445976_1	1121904.ARBP01000001_gene5847	6.78e-203	670.0	COG3119@1|root,COG3119@2|Bacteria,4PKKW@976|Bacteroidetes,47Y6A@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_445976_0	886293.Sinac_7111	4.545e-321	1018.0	COG2010@1|root,COG2010@2|Bacteria,2IYDW@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CMS3_k127_445976_9	314260.PB2503_11144	2.229e-41	172.0	COG1668@1|root,COG1668@2|Bacteria,1R62N@1224|Proteobacteria,2U1RZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS3_k127_445976_7	1047013.AQSP01000052_gene2600	3.942e-87	298.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_445976_13	1177154.Y5S_00505	2.296e-09	62.0	2ARAZ@1|root,2ZUT3@2|Bacteria,1RDFY@1224|Proteobacteria,1S5N7@1236|Gammaproteobacteria,1XQRR@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF3332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3332
CMS3_k127_445976_5	1196324.A374_17134	1.292e-135	469.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS3_k127_445976_3	671143.DAMO_0810	4.137e-161	526.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_445976_14	382464.ABSI01000023_gene558	2.03e-06	56.0	COG0721@1|root,COG0721@2|Bacteria,46WBS@74201|Verrucomicrobia,2IURF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CMS3_k127_445976_2	1192034.CAP_0222	2.497e-170	558.0	COG1028@1|root,COG1028@2|Bacteria,1R4BM@1224|Proteobacteria,42PS2@68525|delta/epsilon subdivisions,2WJJK@28221|Deltaproteobacteria,2YU82@29|Myxococcales	28221|Deltaproteobacteria	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS3_k127_445976_8	1254432.SCE1572_00820	1.555e-63	228.0	COG3220@1|root,COG3220@2|Bacteria,1Q38G@1224|Proteobacteria,438ZE@68525|delta/epsilon subdivisions,2X44P@28221|Deltaproteobacteria,2YY8Z@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
CMS3_k127_445976_11	1192034.CAP_8307	3.24e-17	94.0	2BGYF@1|root,32AYH@2|Bacteria,1QAYP@1224|Proteobacteria,435CU@68525|delta/epsilon subdivisions,2WZQB@28221|Deltaproteobacteria,2Z2IB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_445976_10	671143.DAMO_2125	1.992e-24	112.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_445976_6	391625.PPSIR1_06271	2.339e-124	425.0	COG0500@1|root,COG2226@2|Bacteria,1QZSU@1224|Proteobacteria,42PXS@68525|delta/epsilon subdivisions,2X7UZ@28221|Deltaproteobacteria,2Z3I9@29|Myxococcales	28221|Deltaproteobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
CMS3_k127_445976_15	102232.GLO73106DRAFT_00028380	0.0002577	55.0	COG0457@1|root,COG0457@2|Bacteria,1G0IA@1117|Cyanobacteria	1117|Cyanobacteria	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6
CMS3_k127_445976_12	290398.Csal_1309	6.693e-11	76.0	COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria,1RN1K@1236|Gammaproteobacteria,1XK99@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	NRho,Rhomboid
CMS3_k127_445976_4	443144.GM21_0928	3.531e-139	464.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,43T57@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS3_k127_4474500_4	107636.JQNK01000001_gene57	1.797e-10	64.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,36ZMD@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS3_k127_4474500_0	583355.Caka_0965	3.551e-205	683.0	COG0823@1|root,COG1413@1|root,COG0823@2|Bacteria,COG1413@2|Bacteria,46XCP@74201|Verrucomicrobia,3K9X8@414999|Opitutae	414999|Opitutae	U	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4474500_2	530564.Psta_1513	4.776e-164	566.0	COG1914@1|root,COG1914@2|Bacteria,2IYEM@203682|Planctomycetes	203682|Planctomycetes	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4474500_1	479434.Sthe_2689	1.231e-175	560.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi,27YUC@189775|Thermomicrobia	189775|Thermomicrobia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.99.24	ko:K11173	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
CMS3_k127_4474500_3	1380394.JADL01000001_gene1966	1.016e-142	463.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,2JW4U@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS3_k127_4526250_5	1449353.JQMQ01000005_gene2990	1.536e-06	61.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria,2NNJF@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
CMS3_k127_4526250_2	153721.MYP_1117	5.752e-65	234.0	COG4714@1|root,COG4714@2|Bacteria,4NEVY@976|Bacteroidetes,47ND0@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
CMS3_k127_4526250_1	391598.FBBAL38_09852	2.949e-120	422.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS3_k127_4526250_4	1157632.AQWQ01000016_gene3320	1.562e-11	79.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4526250_0	1129794.C427_1223	1.108e-126	443.0	COG2706@1|root,COG3391@1|root,COG3637@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,COG3637@2|Bacteria,1QWRQ@1224|Proteobacteria,1T4S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4526250_3	1396141.BATP01000003_gene4967	5.208e-58	231.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
CMS3_k127_45380_6	313596.RB2501_08740	1.408e-23	110.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,1HWNT@117743|Flavobacteriia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
CMS3_k127_45380_3	1384054.N790_03440	7.597e-37	154.0	COG0454@1|root,COG0456@2|Bacteria,1RAJC@1224|Proteobacteria,1S1YW@1236|Gammaproteobacteria,1X6QN@135614|Xanthomonadales	135614|Xanthomonadales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_45380_13	1121033.AUCF01000006_gene4184	1.152e-11	70.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U2X8@28211|Alphaproteobacteria,2JPQ4@204441|Rhodospirillales	204441|Rhodospirillales	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_45380_1	391625.PPSIR1_38876	7.173e-135	442.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2WM9T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Peptidase M20	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_45380_5	404589.Anae109_3642	8.16e-34	135.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2YUZQ@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_45380_14	1142394.PSMK_06260	1.876e-08	67.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_45380_0	518766.Rmar_1705	0.0	1013.0	COG1960@1|root,COG1960@2|Bacteria,4P1V8@976|Bacteroidetes,1FIUE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Domain of unknown function (DUF1974)	-	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
CMS3_k127_45380_12	525909.Afer_1918	2.84e-12	74.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_45380_8	1121104.AQXH01000001_gene1382	4.338e-23	106.0	COG3182@1|root,COG3182@2|Bacteria	2|Bacteria	E	Iron-regulated membrane protein	-	-	-	ko:K09939	-	-	-	-	ko00000	-	-	-	PepSY_TM
CMS3_k127_45380_15	344747.PM8797T_26520	5.487e-07	63.0	COG1413@1|root,COG1413@2|Bacteria,2J0ID@203682|Planctomycetes	203682|Planctomycetes	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_PBS
CMS3_k127_45380_7	635013.TherJR_1408	2.201e-23	116.0	COG1287@1|root,COG1287@2|Bacteria,1V7EF@1239|Firmicutes,24M0T@186801|Clostridia,265QD@186807|Peptococcaceae	186801|Clostridia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_45380_4	1133850.SHJG_3961	2.914e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,2GJPK@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_C_6,TetR_N
CMS3_k127_45380_11	595460.RRSWK_03527	1.668e-14	87.0	COG2304@1|root,COG2304@2|Bacteria,2J43F@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_3
CMS3_k127_45380_16	309807.SRU_2431	0.000863	52.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,4PF1U@976|Bacteroidetes,1FK0E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2,Pro_isomerase
CMS3_k127_45380_2	1031711.RSPO_c03271	8.767e-56	215.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,1K2SD@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gst8	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_C_4,GST_N_3
CMS3_k127_45380_10	391625.PPSIR1_41114	8.198e-16	90.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42U5E@68525|delta/epsilon subdivisions,2WSV3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	thioesterase	-	-	3.1.2.28	ko:K07107,ko:K12073	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
CMS3_k127_45380_9	1142394.PSMK_30420	1.215e-20	105.0	2E2CP@1|root,32XHN@2|Bacteria,2J0IA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_455361_2	662479.C440_14604	0.0001105	55.0	COG1413@1|root,arCOG04653@2157|Archaea,2XUXY@28890|Euryarchaeota,23SVC@183963|Halobacteria	183963|Halobacteria	C	COG1413 FOG HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_455361_0	1128421.JAGA01000002_gene1304	2.245e-53	211.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_455361_1	574087.Acear_2312	6.293e-11	64.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3WAIJ@53433|Halanaerobiales	186801|Clostridia	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_4577856_2	1121930.AQXG01000001_gene1303	7.821e-87	303.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_4577856_1	479434.Sthe_3384	7.364e-88	301.0	COG1171@1|root,COG1171@2|Bacteria,2G5YN@200795|Chloroflexi,27XYI@189775|Thermomicrobia	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_4577856_0	1236902.ANAS01000022_gene77	4.807e-88	315.0	2DB71@1|root,2Z7JE@2|Bacteria,2I2SN@201174|Actinobacteria,4EMKV@85012|Streptosporangiales	201174|Actinobacteria	C	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
CMS3_k127_4577856_5	1463900.JOIX01000070_gene4487	5.776e-21	109.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HTH_31
CMS3_k127_4577856_3	1123508.JH636449_gene7349	7.657e-65	252.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4577856_4	1267535.KB906767_gene4499	5.637e-33	132.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_4593061_1	362663.ECP_3889	0.0002285	50.0	COG5645@1|root,COG5645@2|Bacteria,1MZ8R@1224|Proteobacteria,1S9TX@1236|Gammaproteobacteria,3XPW1@561|Escherichia	1236|Gammaproteobacteria	S	cellular response to DNA damage stimulus	yidQ	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	-	-	-	-	-	-	-	-	-	DUF1375
CMS3_k127_4593061_0	756272.Plabr_4345	2.71e-51	191.0	COG0233@1|root,COG0233@2|Bacteria,2IYYY@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS3_k127_459455_0	439235.Dalk_1804	1.333e-137	472.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,2MK6C@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_459455_1	521674.Plim_3536	1.358e-121	401.0	COG3345@1|root,COG3345@2|Bacteria,2J1YM@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_459455_2	448385.sce6990	1.391e-12	79.0	COG3049@1|root,COG3049@2|Bacteria,1RHU2@1224|Proteobacteria,42XVE@68525|delta/epsilon subdivisions,2WT93@28221|Deltaproteobacteria,2YW4E@29|Myxococcales	28221|Deltaproteobacteria	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_4625478_1	224325.AF_1725	2.226e-45	173.0	COG1793@1|root,arCOG01347@2157|Archaea,2XTCK@28890|Euryarchaeota,246K0@183980|Archaeoglobi	2157|Archaea	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
CMS3_k127_4625478_0	1123242.JH636435_gene1762	9.695e-56	207.0	COG1273@1|root,COG1273@2|Bacteria,2J4I3@203682|Planctomycetes	203682|Planctomycetes	S	Ku70/Ku80 beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Ku
CMS3_k127_4625478_3	1280947.HY30_04305	1.927e-10	74.0	COG5553@1|root,COG5553@2|Bacteria,1PNX4@1224|Proteobacteria,2UZQZ@28211|Alphaproteobacteria,43ZRM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4625478_2	640510.BC1001_4762	7.948e-35	147.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VVIX@28216|Betaproteobacteria,1K0FV@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4
CMS3_k127_4625478_4	981369.JQMJ01000004_gene5149	1.409e-09	70.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GJ09@201174|Actinobacteria,2NE97@228398|Streptacidiphilus	201174|Actinobacteria	EGMP	Protein of unknown function (DUF1416)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
CMS3_k127_463258_21	1463895.JODA01000052_gene3373	5.819e-07	55.0	COG4188@1|root,COG4188@2|Bacteria,2GJVV@201174|Actinobacteria	201174|Actinobacteria	M	Platelet-activating factor acetylhydrolase, plasma intracellular isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS3_k127_463258_1	1123242.JH636436_gene23	0.0	1328.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_463258_10	1242864.D187_003284	4.584e-51	187.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	XK27_02315	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS3_k127_463258_23	1460634.JCM19037_2771	9.32e-05	56.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M_N,CarboxypepD_reg
CMS3_k127_463258_26	679199.HMPREF9332_00132	0.0008026	49.0	COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,2G2Z3@200643|Bacteroidia	976|Bacteroidetes	S	DoxX family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CMS3_k127_463258_15	641491.DND132_1571	7.969e-37	154.0	COG0607@1|root,COG0607@2|Bacteria,1RM2N@1224|Proteobacteria,43093@68525|delta/epsilon subdivisions,2WVD8@28221|Deltaproteobacteria,2M8VF@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_463258_13	1454202.PPBDW_130296___1	2.016e-45	178.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,1RMRX@1236|Gammaproteobacteria,1XV0Z@135623|Vibrionales	135623|Vibrionales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
CMS3_k127_463258_2	314230.DSM3645_10132	1.022e-222	721.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_463258_25	408672.NBCG_04609	0.0005947	54.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2I66N@201174|Actinobacteria,4DQ53@85009|Propionibacteriales	201174|Actinobacteria	O	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cleaved_Adhesin,Kelch_1,Peptidase_S8
CMS3_k127_463258_19	215803.DB30_1234	1.438e-13	85.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_463258_20	1463934.JOCF01000024_gene6087	9.685e-10	73.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_463258_4	314230.DSM3645_18261	4.873e-155	504.0	COG1520@1|root,COG1520@2|Bacteria,2IXD2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_463258_22	661478.OP10G_0095	6.938e-06	57.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K03671,ko:K07152	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03029,ko03110	-	-	-	AhpC-TSA,Glyco_hydro_8,Redoxin,SCO1-SenC,Thioredoxin,Thioredoxin_8
CMS3_k127_463258_17	344747.PM8797T_11571	1.431e-23	118.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,2IXTF@203682|Planctomycetes	203682|Planctomycetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_463258_18	1295642.H839_14079	2.135e-18	100.0	2AFVE@1|root,315XY@2|Bacteria,1V9WC@1239|Firmicutes,4HJ2Y@91061|Bacilli,1WHEF@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_463258_6	391625.PPSIR1_02111	2.266e-104	352.0	COG0391@1|root,COG0391@2|Bacteria,1NW3K@1224|Proteobacteria,42QAP@68525|delta/epsilon subdivisions,2WIZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Uncharacterised protein family UPF0052	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
CMS3_k127_463258_0	1123508.JH636452_gene7057	0.0	1529.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2J2J0@203682|Planctomycetes	203682|Planctomycetes	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT,VWA_3
CMS3_k127_463258_9	314230.DSM3645_19703	2.395e-52	199.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria,2IXR8@203682|Planctomycetes	203682|Planctomycetes	MO	MucD-putative a secreted serine proteinase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
CMS3_k127_463258_24	1403819.BATR01000171_gene5859	0.0004867	48.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria	2|Bacteria	M	metalloendopeptidase activity	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS3_k127_463258_14	1449126.JQKL01000036_gene1950	2.864e-43	178.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
CMS3_k127_463258_11	1041159.AZUW01000063_gene411	7.718e-48	195.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,2U7SC@28211|Alphaproteobacteria,4BI87@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_463258_3	1041159.AZUW01000062_gene3637	1.027e-167	550.0	COG1404@1|root,COG1404@2|Bacteria,1PSEZ@1224|Proteobacteria,2V4M5@28211|Alphaproteobacteria,4BFDK@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS3_k127_463258_16	416348.Hlac_0778	1.205e-27	119.0	COG0494@1|root,arCOG01072@2157|Archaea,2XWJS@28890|Euryarchaeota,23VF0@183963|Halobacteria	183963|Halobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_463258_8	880070.Cycma_4030	1.91e-66	252.0	COG1331@1|root,COG1331@2|Bacteria,4NSMA@976|Bacteroidetes	976|Bacteroidetes	O	pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
CMS3_k127_463258_7	314230.DSM3645_10062	4.405e-70	263.0	COG1889@1|root,COG1889@2|Bacteria,2J51S@203682|Planctomycetes	203682|Planctomycetes	J	Fibrillarin	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_463258_12	1320556.AVBP01000007_gene836	1.802e-46	186.0	COG2520@1|root,COG2520@2|Bacteria,1QZWN@1224|Proteobacteria,2TYG6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS3_k127_463258_5	1267535.KB906767_gene3674	9.643e-127	417.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	MA20_02630	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_4653609_2	222534.KB893714_gene1600	1.412e-09	61.0	28N8D@1|root,2ZBCT@2|Bacteria,2GP6B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4653609_0	298653.Franean1_3143	1.554e-140	457.0	COG5659@1|root,COG5659@2|Bacteria,2IENZ@201174|Actinobacteria,4EXB7@85013|Frankiales	2|Bacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS3_k127_4653609_1	656024.FsymDg_1667	9.309e-15	74.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4EWK4@85013|Frankiales	201174|Actinobacteria	L	PFAM RNA-directed DNA polymerase (reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,Intron_maturas2,RVT_1
CMS3_k127_4664960_9	237368.SCABRO_00024	4.541e-29	121.0	COG0745@1|root,COG0745@2|Bacteria,2J01B@203682|Planctomycetes	203682|Planctomycetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_4664960_15	471856.Jden_1999	3.52e-05	53.0	2E77D@1|root,331R6@2|Bacteria,2IRQY@201174|Actinobacteria	201174|Actinobacteria	S	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
CMS3_k127_4664960_14	1218074.BAXZ01000001_gene114	2.147e-05	56.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VV3X@28216|Betaproteobacteria,1K7PW@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Pfam Response regulator receiver	cheY1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_4664960_13	269799.Gmet_0184	1.698e-06	60.0	COG1406@1|root,COG1406@2|Bacteria	2|Bacteria	N	Chemotaxis phosphatase CheX	cheX40H	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
CMS3_k127_4664960_2	1089551.KE386572_gene3673	2.592e-96	323.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2TT0H@28211|Alphaproteobacteria,4BR33@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS3_k127_4664960_5	529818.AMSG_00581T0	5.36e-59	231.0	COG0079@1|root,KOG0633@2759|Eukaryota	2759|Eukaryota	E	histidinol-phosphate transaminase activity	HIS5	GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0010038,GO:0010045,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9,5.3.1.16	ko:K00817,ko:K01814	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R04640	RC00006,RC00888,RC00945	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iMM904.YIL116W,iND750.YIL116W	Aminotran_1_2
CMS3_k127_4664960_4	1089551.KE386572_gene3674	1.264e-73	256.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,4BPYC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9,3.1.3.15,4.2.1.19	ko:K00817,ko:K01089,ko:K01693	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03013,R03243,R03457	RC00006,RC00017,RC00888,RC00932	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	IGPD
CMS3_k127_4664960_7	1089551.KE386572_gene3675	1.874e-36	156.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2TTT4@28211|Alphaproteobacteria,4BQXJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Glutamine amidotransferase class-I	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_4664960_3	1121360.AUAQ01000011_gene564	1.199e-85	295.0	COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,22JQJ@1653|Corynebacteriaceae	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007	4.1.3.27	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023,M00026	R00985,R00986,R04558	RC00010,RC01190,RC01943,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_4664960_0	1089551.KE386572_gene3677	1.018e-145	477.0	COG0106@1|root,COG0139@1|root,COG0106@2|Bacteria,COG0139@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,4BQ2C@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_4664960_1	67593.Physo108397	1.324e-113	379.0	COG0141@1|root,KOG2697@2759|Eukaryota,3QAS9@4776|Peronosporales	4776|Peronosporales	E	Histidinol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Histidinol_dh
CMS3_k127_4664960_10	518766.Rmar_2096	6.037e-25	117.0	COG0352@1|root,COG0352@2|Bacteria,4PIN4@976|Bacteroidetes,1FJFF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS3_k127_4664960_6	314230.DSM3645_25572	2.024e-41	170.0	COG0611@1|root,COG0611@2|Bacteria,2IZG9@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_4664960_12	1209989.TepiRe1_0539	1.922e-22	104.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,42GXN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0079, ATPase	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS3_k127_4664960_11	985665.HPL003_03670	4.15e-24	111.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4664960_8	1131269.AQVV01000010_gene2437	3.163e-29	134.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS3_k127_4667671_5	344747.PM8797T_10149	8.424e-115	385.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4667671_16	1068980.ARVW01000001_gene2984	3.935e-14	82.0	COG3049@1|root,COG3049@2|Bacteria,2IA2S@201174|Actinobacteria,4E17S@85010|Pseudonocardiales	201174|Actinobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_4667671_4	861299.J421_2225	3.948e-121	428.0	COG3119@1|root,COG3119@2|Bacteria,1ZUN9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_4667671_11	1284352.AOIG01000013_gene3550	1.092e-45	189.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
CMS3_k127_4667671_8	493475.GARC_2930	1.931e-80	295.0	COG1228@1|root,COG1228@2|Bacteria,1RCA0@1224|Proteobacteria,1S08B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CIA30
CMS3_k127_4667671_6	666685.R2APBS1_1401	6.442e-94	321.0	COG2382@1|root,COG2382@2|Bacteria,1R6XH@1224|Proteobacteria,1SPDA@1236|Gammaproteobacteria,1X4S9@135614|Xanthomonadales	135614|Xanthomonadales	P	Enterochelin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_4667671_7	36809.MAB_1125c	1.509e-84	289.0	COG0454@1|root,COG0456@2|Bacteria,2I9PD@201174|Actinobacteria,236TT@1762|Mycobacteriaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
CMS3_k127_4667671_10	314271.RB2654_06439	5.704e-59	231.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,Cadherin,FG-GAP,Glyco_hydro_26,HemolysinCabind,Integrin_beta,Lipase_GDSL_2
CMS3_k127_4667671_3	1267533.KB906735_gene5020	9.095e-123	432.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_4667671_13	1095769.CAHF01000006_gene1854	6.675e-30	139.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VHHM@28216|Betaproteobacteria,478DK@75682|Oxalobacteraceae	28216|Betaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_4667671_2	246197.MXAN_5538	3.083e-133	440.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2WNZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS3_k127_4667671_12	1453500.AT05_05490	8.877e-37	148.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CMS3_k127_4667671_0	1297742.A176_05050	1.629e-308	968.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2WM27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
CMS3_k127_4667671_1	246197.MXAN_5543	6.027e-176	580.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CMS3_k127_4667671_14	1396418.BATQ01000020_gene5029	1.485e-21	111.0	COG2836@1|root,COG2836@2|Bacteria,46VBD@74201|Verrucomicrobia,2IUEY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS3_k127_4667671_9	1173027.Mic7113_1068	1.441e-65	227.0	COG0432@1|root,COG0432@2|Bacteria,1G61Z@1117|Cyanobacteria,1HBAH@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_4667671_17	1259795.ARJK01000003_gene713	6.882e-11	73.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,42FBX@68295|Thermoanaerobacterales	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS3_k127_4667671_18	443144.GM21_1091	4.417e-07	61.0	COG4968@1|root,COG4968@2|Bacteria,1N31J@1224|Proteobacteria	1224|Proteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS3_k127_470402_0	1121930.AQXG01000001_gene1592	1.993e-277	866.0	COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IP3R@117747|Sphingobacteriia	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_470402_1	1291050.JAGE01000001_gene867	9.16e-167	572.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_470402_2	1298865.H978DRAFT_0138	2.664e-131	441.0	COG2133@1|root,COG2133@2|Bacteria,1R5SW@1224|Proteobacteria,1S1CW@1236|Gammaproteobacteria,464YU@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_470402_4	583355.Caka_0954	4.655e-60	235.0	COG3828@1|root,COG3828@2|Bacteria,46W06@74201|Verrucomicrobia,3K9VX@414999|Opitutae	414999|Opitutae	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS3_k127_470402_5	1341181.FLJC2902T_05210	1.128e-35	152.0	2A9UH@1|root,30Z2C@2|Bacteria,4PD3Q@976|Bacteroidetes,1IDMI@117743|Flavobacteriia,2NYRQ@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_470402_3	765912.Thimo_0714	2.293e-70	244.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1S237@1236|Gammaproteobacteria,1WWYK@135613|Chromatiales	135613|Chromatiales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS3_k127_475890_11	314230.DSM3645_18761	1.71e-16	82.0	COG0267@1|root,COG0267@2|Bacteria,2J0Q2@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS3_k127_475890_6	1449976.KALB_3452	1.551e-43	168.0	COG1028@1|root,COG1028@2|Bacteria,2H0SM@201174|Actinobacteria,4E07R@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CMS3_k127_475890_3	485913.Krac_2147	2.954e-91	307.0	COG1024@1|root,COG1024@2|Bacteria,2G6G6@200795|Chloroflexi	2|Bacteria	I	PFAM Enoyl-CoA hydratase isomerase	MA20_38145	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS3_k127_475890_4	485913.Krac_2131	1.799e-89	310.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_475890_0	485913.Krac_2128	4.244e-206	649.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi	200795|Chloroflexi	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS3_k127_475890_17	388413.ALPR1_16818	0.0006473	51.0	29BRG@1|root,2ZYPV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_475890_8	648885.KB316282_gene331	5.704e-40	164.0	2DPPD@1|root,332VE@2|Bacteria,1N8XI@1224|Proteobacteria,2UH9Q@28211|Alphaproteobacteria,1JS6A@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_475890_9	926560.KE387023_gene3374	1.486e-34	142.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_475890_16	93220.LV28_02075	1.031e-06	59.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2VSKC@28216|Betaproteobacteria,1KH5R@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_475890_7	521674.Plim_4143	1.861e-43	169.0	COG0543@1|root,COG0543@2|Bacteria,2IYMI@203682|Planctomycetes	203682|Planctomycetes	C	Dihydroorotate dehydrogenase	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CMS3_k127_475890_10	1278306.KB906920_gene1594	5.453e-31	129.0	COG4399@1|root,COG4399@2|Bacteria,37A4K@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
CMS3_k127_475890_5	502025.Hoch_5425	1.301e-63	222.0	COG2316@1|root,COG2316@2|Bacteria,1RA50@1224|Proteobacteria,42QZZ@68525|delta/epsilon subdivisions,2WMUN@28221|Deltaproteobacteria,2Z0YN@29|Myxococcales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS3_k127_475890_1	555088.DealDRAFT_2903	1.504e-138	464.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,42K30@68298|Syntrophomonadaceae	186801|Clostridia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS3_k127_475890_12	1200792.AKYF01000006_gene1410	2.345e-13	81.0	28XGS@1|root,2ZJE7@2|Bacteria,1V1QY@1239|Firmicutes,4HGQC@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_475890_15	1415630.U771_12905	5.372e-08	65.0	COG0400@1|root,COG0400@2|Bacteria,1N3A3@1224|Proteobacteria,1S9QE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phospholipase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS3_k127_475890_13	595460.RRSWK_03057	3.995e-12	78.0	COG1595@1|root,COG1595@2|Bacteria,2IZJK@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_475890_2	502025.Hoch_1711	3.556e-92	339.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K11912,ko:K20333	ko02024,ko02025,ko03070,map02024,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,PEGA,Pkinase,TIR_2
CMS3_k127_4783835_8	1254432.SCE1572_52115	4.008e-36	143.0	COG5031@1|root,COG5031@2|Bacteria,1NKS8@1224|Proteobacteria,434J5@68525|delta/epsilon subdivisions,2WYWC@28221|Deltaproteobacteria,2Z0SR@29|Myxococcales	28221|Deltaproteobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4783835_7	1173026.Glo7428_3718	9.919e-43	175.0	COG1749@1|root,COG1749@2|Bacteria,1G2ZW@1117|Cyanobacteria	1117|Cyanobacteria	N	Ig domain protein group 1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,DUF4082
CMS3_k127_4783835_2	861299.J421_1372	4.142e-140	470.0	COG1506@1|root,COG1506@2|Bacteria,1ZT9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_4783835_3	870187.Thini_1805	9.384e-123	422.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,1RPYU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	homoserine dehydrogenase	strU	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_3
CMS3_k127_4783835_6	671143.DAMO_0255	1.846e-65	244.0	COG0438@1|root,COG3754@1|root,COG4372@1|root,COG5610@1|root,COG0438@2|Bacteria,COG3754@2|Bacteria,COG4372@2|Bacteria,COG5610@2|Bacteria,2NR6D@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	sll1424	-	2.1.1.80,3.1.1.61	ko:K01991,ko:K02557,ko:K07161,ko:K07484,ko:K13924,ko:K20444,ko:K21471	ko02020,ko02026,ko02030,ko02040,map02020,map02026,map02030,map02040	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01005,ko01011,ko02000,ko02022,ko02035	1.A.30.1,1.B.18,4.D.1.3	GT2,GT4	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,zf-IS66
CMS3_k127_4783835_1	1121104.AQXH01000001_gene862	2.715e-227	736.0	COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_4783835_5	449447.MAE_61060	5.048e-77	283.0	COG2931@1|root,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
CMS3_k127_4783835_0	909663.KI867150_gene2148	7.992e-245	807.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
CMS3_k127_480469_1	324602.Caur_2858	2.213e-83	297.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CMS3_k127_480469_0	502025.Hoch_5134	2.804e-103	364.0	COG0604@1|root,COG0604@2|Bacteria,1N1KK@1224|Proteobacteria	1224|Proteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS3_k127_480469_3	1283299.AUKG01000001_gene2965	7.096e-07	59.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CRPM@84995|Rubrobacteria	84995|Rubrobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4824637_25	1095769.CAHF01000022_gene194	3.764e-09	70.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2WDK7@28216|Betaproteobacteria,4786Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS3_k127_4824637_8	211165.AJLN01000079_gene370	1.02e-113	378.0	COG1262@1|root,COG1262@2|Bacteria,1G4C8@1117|Cyanobacteria,1JJTS@1189|Stigonemataceae	1117|Cyanobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_4824637_4	1440053.JOEI01000012_gene4389	2.165e-166	533.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS3_k127_4824637_12	1144275.COCOR_02313	2.556e-71	257.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,2YUZJ@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS3_k127_4824637_11	1123376.AUIU01000016_gene297	8.773e-81	284.0	COG0777@1|root,COG0777@2|Bacteria,3J0CK@40117|Nitrospirae	40117|Nitrospirae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_4824637_13	1120985.AUMI01000015_gene1461	2.136e-62	221.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H407@909932|Negativicutes	909932|Negativicutes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS3_k127_4824637_7	479434.Sthe_1252	2.989e-132	432.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi,27XWV@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS3_k127_4824637_5	1499967.BAYZ01000157_gene583	2.163e-136	441.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS3_k127_4824637_19	477974.Daud_0086	3.561e-42	173.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,260U4@186807|Peptococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS3_k127_4824637_16	756272.Plabr_2560	4.105e-54	217.0	COG0515@1|root,COG0515@2|Bacteria,2IYFB@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4824637_15	521674.Plim_2216	3.984e-55	203.0	COG0005@1|root,COG0005@2|Bacteria,2IX9R@203682|Planctomycetes	203682|Planctomycetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_4824637_14	479434.Sthe_1363	9.569e-59	212.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,27Y8N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS3_k127_4824637_6	504472.Slin_5007	2.204e-132	442.0	2CD2X@1|root,2Z7RW@2|Bacteria,4NI6Q@976|Bacteroidetes,47M77@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4824637_9	237368.SCABRO_01734	3.39e-105	353.0	COG3754@1|root,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX,RgpF
CMS3_k127_4824637_17	1121939.L861_07865	1.153e-44	175.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria	1224|Proteobacteria	Q	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,Ubie_methyltran
CMS3_k127_4824637_18	292459.STH1622	9.493e-44	171.0	COG0457@1|root,COG3359@1|root,COG0457@2|Bacteria,COG3359@2|Bacteria,1TQQU@1239|Firmicutes	1239|Firmicutes	L	Exonuclease	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
CMS3_k127_4824637_2	997346.HMPREF9374_0253	2.215e-210	691.0	COG1205@1|root,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli	91061|Bacilli	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
CMS3_k127_4824637_27	478741.JAFS01000001_gene1166	0.0001871	55.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia,37FXR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS3_k127_4824637_24	373903.Hore_12990	3.155e-14	87.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia	186801|Clostridia	N	-transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
CMS3_k127_4824637_22	237368.SCABRO_02220	1.203e-31	143.0	COG1277@1|root,COG1277@2|Bacteria,2J0HW@203682|Planctomycetes	203682|Planctomycetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS3_k127_4824637_10	1254432.SCE1572_14660	5.622e-83	289.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4824637_1	1305737.JAFX01000001_gene1984	1.103e-242	765.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS3_k127_4824637_21	768706.Desor_4545	3.388e-34	138.0	COG0745@1|root,COG0745@2|Bacteria,1VK36@1239|Firmicutes,24TSA@186801|Clostridia,2665I@186807|Peptococcaceae	186801|Clostridia	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_4824637_20	653733.Selin_0596	2.676e-40	171.0	COG0591@1|root,COG2203@1|root,COG2208@1|root,COG0591@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3	ko:K01079,ko:K07315	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	FHA,GAF,GAF_2,HATPase_c,HisKA,SpoIIE
CMS3_k127_4824637_26	1458462.JNLK01000001_gene672	8.06e-08	60.0	COG2172@1|root,COG2172@2|Bacteria,1VAPM@1239|Firmicutes,24J9J@186801|Clostridia,27MMM@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
CMS3_k127_4824637_23	1142394.PSMK_04940	5.45e-25	118.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448,ko:K07273	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_2,Amidase_3,DUF1906,Glyco_hydro_25,LysM,Peptidase_M23
CMS3_k127_4824637_3	1499967.BAYZ01000156_gene567	1.894e-180	591.0	COG2070@1|root,COG2070@2|Bacteria	2|Bacteria	S	nitronate monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS3_k127_4824637_0	96561.Dole_1676	7.976e-272	897.0	COG0236@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,2MJ23@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,FabA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_4827356_12	502025.Hoch_1711	2.316e-50	201.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K11912,ko:K20333	ko02024,ko02025,ko03070,map02024,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,PEGA,Pkinase,TIR_2
CMS3_k127_4827356_6	1122176.KB903589_gene4560	2.362e-70	265.0	COG0457@1|root,COG0457@2|Bacteria,4NND8@976|Bacteroidetes	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_4827356_19	1121481.AUAS01000007_gene1166	3.924e-12	79.0	COG2849@1|root,COG2849@2|Bacteria,4NW92@976|Bacteroidetes,47WDC@768503|Cytophagia	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4827356_17	671065.MetMK1DRAFT_00016260	4.285e-18	98.0	COG0666@1|root,arCOG04004@2157|Archaea,2XS0N@28889|Crenarchaeota	28889|Crenarchaeota	S	ankyrin repeats	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
CMS3_k127_4827356_18	926692.AZYG01000038_gene1077	5.041e-16	88.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia	186801|Clostridia	S	acyl-CoA thioester hydrolase, YbgC YbaW family	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_4827356_20	861299.J421_0243	5.266e-05	55.0	COG1413@1|root,COG4219@1|root,COG1413@2|Bacteria,COG4219@2|Bacteria,1ZUUA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,Peptidase_M56
CMS3_k127_4827356_0	1189612.A33Q_3959	0.0	1553.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS3_k127_4827356_11	2903.EOD20306	9.37e-57	207.0	COG0652@1|root,KOG0884@2759|Eukaryota	2759|Eukaryota	O	peptidyl-prolyl cis-trans isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
CMS3_k127_4827356_3	489825.LYNGBM3L_09400	1.315e-103	354.0	COG1696@1|root,COG1696@2|Bacteria,1G2RR@1117|Cyanobacteria,1H9BT@1150|Oscillatoriales	1117|Cyanobacteria	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_4827356_9	530564.Psta_3244	5.148e-62	234.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
CMS3_k127_4827356_15	1297742.A176_04293	1.279e-25	124.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,43CIK@68525|delta/epsilon subdivisions,2WQ8R@28221|Deltaproteobacteria,2Z1G2@29|Myxococcales	28221|Deltaproteobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS3_k127_4827356_7	1403819.BATR01000178_gene5964	2.521e-70	265.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_4827356_5	1267533.KB906733_gene3472	2.506e-76	287.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_4827356_16	1210884.HG799462_gene8065	7.388e-24	108.0	COG1595@1|root,COG1595@2|Bacteria,2IZ9U@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CMS3_k127_4827356_10	1185876.BN8_02230	3.707e-59	216.0	COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes,47RDA@768503|Cytophagia	976|Bacteroidetes	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS3_k127_4827356_2	1122612.AUBA01000008_gene2171	1.355e-125	413.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,2K0SH@204457|Sphingomonadales	204457|Sphingomonadales	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS3_k127_4827356_8	575540.Isop_1583	1.918e-64	245.0	COG1884@1|root,COG1884@2|Bacteria,2J2EV@203682|Planctomycetes	203682|Planctomycetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS3_k127_4827356_1	1521187.JPIM01000071_gene2417	4.541e-294	954.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,2G5TP@200795|Chloroflexi,376VM@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
CMS3_k127_4827356_13	530564.Psta_2855	2.14e-38	167.0	COG2912@1|root,COG2912@2|Bacteria,2J4QH@203682|Planctomycetes	203682|Planctomycetes	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
CMS3_k127_4827356_4	1038858.AXBA01000002_gene3830	1.18e-96	336.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,3EY31@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_4838256_2	1201288.M900_A0412	2.284e-07	61.0	COG3677@1|root,COG3677@2|Bacteria,1NUJD@1224|Proteobacteria,42ZJP@68525|delta/epsilon subdivisions,2MTUZ@213481|Bdellovibrionales,2WUVR@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4838256_1	1123242.JH636435_gene1148	1.205e-09	70.0	COG0515@1|root,COG0515@2|Bacteria	1123242.JH636435_gene1148|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4838256_0	861299.J421_3227	3.872e-164	526.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_4839166_8	1382356.JQMP01000004_gene418	2.145e-14	76.0	COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_4839166_1	1442599.JAAN01000035_gene626	4.068e-99	336.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1X4UN@135614|Xanthomonadales	135614|Xanthomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_4839166_7	105422.BBPM01000003_gene5590	4.925e-28	131.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,2GK25@201174|Actinobacteria,2NFJZ@228398|Streptacidiphilus	201174|Actinobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
CMS3_k127_4839166_4	448385.sce1492	4.537e-41	172.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
CMS3_k127_4839166_10	28444.JODQ01000002_gene3992	1.812e-06	62.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,4EI7K@85012|Streptosporangiales	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_4839166_2	1089544.KB912942_gene2538	8.525e-68	249.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4DYSE@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS3_k127_4839166_9	1123279.ATUS01000001_gene2451	2.668e-08	66.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1J6KV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS3_k127_4839166_5	1121104.AQXH01000001_gene1784	5.251e-33	133.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes	976|Bacteroidetes	J	endoribonuclease L-PSP	ridA	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS3_k127_4839166_3	382464.ABSI01000010_gene3306	5.443e-45	169.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia,2IUBC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS3_k127_4839166_6	1123288.SOV_1c13030	3.887e-30	139.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H2BF@909932|Negativicutes	909932|Negativicutes	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS3_k127_4839166_0	1121904.ARBP01000010_gene2295	1.044e-144	478.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS3_k127_484191_16	1283300.ATXB01000001_gene260	3.161e-27	131.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87,TPR_2,TPR_8
CMS3_k127_484191_3	595460.RRSWK_03305	4.445e-138	471.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	-
CMS3_k127_484191_12	1300345.LF41_383	3.487e-59	212.0	COG0500@1|root,COG0500@2|Bacteria,1QV5S@1224|Proteobacteria,1SDB5@1236|Gammaproteobacteria,1XDH9@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_484191_23	530564.Psta_3643	8.981e-10	69.0	2C85M@1|root,32UAW@2|Bacteria,2J0CM@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Stress responsive A B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS3_k127_484191_10	1317118.ATO8_08326	9.919e-64	240.0	COG2244@1|root,COG2244@2|Bacteria,1PHY1@1224|Proteobacteria,2UQ94@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_484191_13	1049564.TevJSym_ay00040	9.716e-55	219.0	COG0189@1|root,COG0189@2|Bacteria,1MVN2@1224|Proteobacteria,1RS1C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HJ	GNAT family acetyltransferase	cphA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,RimK
CMS3_k127_484191_21	414684.RC1_1530	4.354e-13	83.0	COG0793@1|root,COG0793@2|Bacteria,1R58Y@1224|Proteobacteria,2U118@28211|Alphaproteobacteria,2JPV1@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_484191_8	1122138.AQUZ01000004_gene892	3.66e-79	278.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria	201174|Actinobacteria	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,DUF1080,GSDH,PKD,ThuA
CMS3_k127_484191_25	208444.JNYY01000024_gene408	9.526e-06	59.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,4E5VH@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	litS	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_484191_11	251221.35213151	2.731e-60	219.0	COG0115@1|root,COG0115@2|Bacteria,1G8CI@1117|Cyanobacteria	1117|Cyanobacteria	H	PFAM aminotransferase, class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_484191_4	1123517.JOMR01000001_gene646	4.628e-136	450.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,4604I@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
CMS3_k127_484191_15	932678.THERU_07080	4.385e-37	147.0	COG0461@1|root,COG0461@2|Bacteria,2G4DW@200783|Aquificae	200783|Aquificae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS3_k127_484191_18	1210884.HG799464_gene10721	3.39e-25	119.0	COG1853@1|root,COG1853@2|Bacteria,2J4S0@203682|Planctomycetes	203682|Planctomycetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS3_k127_484191_22	1038858.AXBA01000011_gene1584	7.454e-12	73.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,3EZMT@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	Probable molybdopterin binding domain	MA20_09420	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,NTP_transf_3
CMS3_k127_484191_2	391625.PPSIR1_35247	4.229e-142	461.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YZ2Q@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_484191_20	351160.RCIX2749	1.815e-13	81.0	COG0226@1|root,arCOG00213@2157|Archaea,2XU6M@28890|Euryarchaeota,2N9KU@224756|Methanomicrobia	224756|Methanomicrobia	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS3_k127_484191_7	1128421.JAGA01000002_gene62	3.546e-94	319.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_484191_9	234267.Acid_0291	8.419e-74	267.0	COG1167@1|root,COG1167@2|Bacteria,3Y4RE@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
CMS3_k127_484191_5	1303518.CCALI_02632	1.676e-111	390.0	COG0214@1|root,COG0214@2|Bacteria	2|Bacteria	H	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
CMS3_k127_484191_14	397278.JOJN01000001_gene3071	9.094e-45	171.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4DUCQ@85009|Propionibacteriales	201174|Actinobacteria	H	SNO glutamine amidotransferase family	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
CMS3_k127_484191_0	706587.Desti_4506	8.944e-221	705.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria,2MQER@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N,ECH_1
CMS3_k127_484191_17	1297742.A176_00643	3.817e-27	123.0	COG3409@1|root,COG3409@2|Bacteria,1QEQE@1224|Proteobacteria,434PQ@68525|delta/epsilon subdivisions,2WZ0Y@28221|Deltaproteobacteria,2Z135@29|Myxococcales	28221|Deltaproteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
CMS3_k127_484191_6	391625.PPSIR1_03213	7.127e-104	358.0	COG2234@1|root,COG2234@2|Bacteria,1MWQ0@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_484191_1	1396141.BATP01000060_gene4615	2.105e-179	575.0	COG1529@1|root,COG1529@2|Bacteria,46UY9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_4843027_20	1123288.SOV_5c02240	3.885e-31	131.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4H35U@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS3_k127_4843027_23	1415774.U728_3247	1.068e-25	123.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,36H7U@31979|Clostridiaceae	186801|Clostridia	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
CMS3_k127_4843027_33	502025.Hoch_3247	6.921e-06	58.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_3247|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4843027_21	118163.Ple7327_4332	4.571e-30	135.0	COG0793@1|root,COG0793@2|Bacteria,1G30Q@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Peptidase family S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
CMS3_k127_4843027_18	643648.Slip_0518	1.519e-40	173.0	COG1085@1|root,COG1085@2|Bacteria,1TS3F@1239|Firmicutes,249P3@186801|Clostridia,42KJY@68298|Syntrophomonadaceae	186801|Clostridia	H	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,DUF4931,GalP_UDP_tr_C,GalP_UDP_transf
CMS3_k127_4843027_7	1242864.D187_006516	1.156e-88	315.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_4843027_32	1254432.SCE1572_15755	1.674e-07	62.0	COG3391@1|root,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria,42XKG@68525|delta/epsilon subdivisions,2WSNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_4843027_10	861299.J421_2347	2.606e-72	262.0	COG0531@1|root,COG0531@2|Bacteria,1ZSST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_4843027_11	1267533.KB906742_gene742	2.458e-69	242.0	COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS3_k127_4843027_34	4787.PITG_07873T0	1.212e-05	59.0	28K2B@1|root,2QSGV@2759|Eukaryota,3QE25@4776|Peronosporales	4776|Peronosporales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_4843027_14	530564.Psta_1971	1.556e-62	226.0	COG0545@1|root,COG0545@2|Bacteria,2IZDZ@203682|Planctomycetes	203682|Planctomycetes	O	FKBP-type peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS3_k127_4843027_31	395493.BegalDRAFT_2155	2.283e-13	80.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
CMS3_k127_4843027_5	290397.Adeh_2584	1.419e-105	353.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42NBC@68525|delta/epsilon subdivisions,2WIMR@28221|Deltaproteobacteria,2Z373@29|Myxococcales	28221|Deltaproteobacteria	E	Arginase family	speB	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_4843027_9	575540.Isop_3442	8.119e-74	267.0	COG1840@1|root,COG1840@2|Bacteria,2IXGE@203682|Planctomycetes	203682|Planctomycetes	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
CMS3_k127_4843027_25	748247.AZKH_0470	1.154e-19	104.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VP0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	cysW_1	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS3_k127_4843027_17	58123.JOFJ01000026_gene2710	1.151e-49	203.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EGCX@85012|Streptosporangiales	201174|Actinobacteria	E	TOBE domain	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS3_k127_4843027_26	502025.Hoch_2450	9.19e-19	102.0	COG3005@1|root,COG3005@2|Bacteria,1QXTY@1224|Proteobacteria,43C6F@68525|delta/epsilon subdivisions,2X7GN@28221|Deltaproteobacteria,2YVYJ@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_4843027_29	1274524.BSONL12_19576	1.722e-15	92.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,1ZBG8@1386|Bacillus	91061|Bacilli	E	COG0747 ABC-type dipeptide transport system, periplasmic component	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_4843027_8	1144319.PMI16_03463	1.217e-84	308.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,2VGZT@28216|Betaproteobacteria,472HF@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	chloride channel	clcB	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CMS3_k127_4843027_3	880073.Calab_1196	2.335e-132	461.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_4843027_0	880073.Calab_1195	1.638e-258	852.0	COG0841@1|root,COG0841@2|Bacteria,2NQI6@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS3_k127_4843027_27	469381.Dpep_0843	7.536e-17	93.0	COG0845@1|root,COG0845@2|Bacteria,3T9UB@508458|Synergistetes	508458|Synergistetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS3_k127_4843027_13	316274.Haur_0387	1.308e-63	241.0	COG0303@1|root,COG0303@2|Bacteria,2G6AK@200795|Chloroflexi,375EW@32061|Chloroflexia	32061|Chloroflexia	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS3_k127_4843027_24	1540221.JQNI01000004_gene90	1.01e-20	109.0	COG0815@1|root,COG0815@2|Bacteria,1WI7B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS3_k127_4843027_35	521674.Plim_0750	0.000475	51.0	COG4372@1|root,COG4372@2|Bacteria,2IZX3@203682|Planctomycetes	203682|Planctomycetes	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4843027_4	247490.KSU1_C0171	2.093e-115	386.0	COG1077@1|root,COG1077@2|Bacteria,2IXSJ@203682|Planctomycetes	203682|Planctomycetes	D	COG1077 Actin-like ATPase involved in cell morphogenesis	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS3_k127_4843027_28	1122221.JHVI01000015_gene1738	1.34e-15	92.0	COG0768@1|root,COG0768@2|Bacteria,1WIPK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Cell division protein FtsI penicillin-binding protein 2	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS3_k127_4843027_16	555079.Toce_0747	3.163e-50	203.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,42EMA@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS3_k127_4843027_22	886293.Sinac_1840	1.496e-26	127.0	COG3170@1|root,COG3170@2|Bacteria,2IX5A@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4843027_12	344747.PM8797T_25391	4.457e-66	247.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_4843027_30	314230.DSM3645_19598	1.748e-14	89.0	COG1520@1|root,COG1520@2|Bacteria,2IZ2Z@203682|Planctomycetes	203682|Planctomycetes	H	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,TPR_6
CMS3_k127_4843027_15	886293.Sinac_1839	7.434e-62	241.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IXY5@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA,VWA_2
CMS3_k127_4843027_19	886293.Sinac_1838	4.887e-40	171.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_4843027_6	575540.Isop_3543	8.833e-91	307.0	COG1721@1|root,COG1721@2|Bacteria,2IWV6@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_4843027_2	886293.Sinac_1836	2.652e-142	460.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_4843027_1	293826.Amet_3576	2.362e-175	559.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,36ET7@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS3_k127_4852598_9	1005395.CSV86_19333	7.945e-08	63.0	COG2273@1|root,COG3210@1|root,COG4625@1|root,COG4932@1|root,COG2273@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin_3,Calx-beta,DUF11,DUF4347,He_PIG,OmpA_membrane,PATR,VCBS
CMS3_k127_4852598_1	1121920.AUAU01000023_gene2392	4.831e-79	278.0	2CCCK@1|root,2Z7UH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS3_k127_4852598_4	290397.Adeh_0228	1.501e-30	139.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,42WUF@68525|delta/epsilon subdivisions,2WSZU@28221|Deltaproteobacteria,2Z1PT@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_4852598_6	706587.Desti_5347	8.522e-26	116.0	2F16M@1|root,33U7Q@2|Bacteria,1NUUZ@1224|Proteobacteria,42ZIZ@68525|delta/epsilon subdivisions,2WUYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4852598_2	886293.Sinac_0410	2.317e-67	255.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_4852598_11	644966.Tmar_0509	5.475e-05	57.0	COG1595@1|root,COG1595@2|Bacteria,1VC8N@1239|Firmicutes,24AUU@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4852598_10	521011.Mpal_2368	8.145e-06	59.0	COG0614@1|root,COG3291@1|root,arCOG02521@1|root,arCOG02508@2157|Archaea,arCOG02521@2157|Archaea,arCOG03611@2157|Archaea	2157|Archaea	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,CBM_6,DUF3344,Lipase_GDSL_2,NHL,NosD,PKD,Peptidase_C1,Peptidase_S8
CMS3_k127_4852598_7	1242864.D187_002871	1.16e-09	71.0	COG1595@1|root,COG1595@2|Bacteria,1Q4ZI@1224|Proteobacteria,42TYH@68525|delta/epsilon subdivisions,2WQNG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	carQ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_4852598_0	886293.Sinac_4145	3.941e-87	326.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_8,WD40
CMS3_k127_4852598_8	1121904.ARBP01000018_gene2643	3.036e-09	70.0	COG5295@1|root,COG5295@2|Bacteria,4PHWW@976|Bacteroidetes,47ST5@768503|Cytophagia	976|Bacteroidetes	UW	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4852598_3	530564.Psta_4044	3.103e-50	191.0	COG0515@1|root,COG0515@2|Bacteria,2IWY8@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4871584_0	344747.PM8797T_16308	8.22e-135	438.0	COG0397@1|root,COG0397@2|Bacteria,2J08F@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
CMS3_k127_4871584_4	1379270.AUXF01000002_gene1799	9.322e-32	130.0	COG1846@1|root,COG1846@2|Bacteria,1ZU5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS3_k127_4871584_3	330214.NIDE0008	4.482e-42	161.0	COG2259@1|root,COG2259@2|Bacteria,3J13I@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS3_k127_4871584_1	1169143.KB911034_gene882	1.877e-79	279.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,1K0N7@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS3_k127_4871584_2	43989.cce_1643	3.888e-63	226.0	COG0778@1|root,COG0778@2|Bacteria,1G42X@1117|Cyanobacteria,3KJXS@43988|Cyanothece	1117|Cyanobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_4871584_5	314225.ELI_05705	7.355e-12	74.0	COG0454@1|root,COG0456@2|Bacteria,1PT7Z@1224|Proteobacteria,2TWI8@28211|Alphaproteobacteria,2KDNF@204457|Sphingomonadales	204457|Sphingomonadales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
CMS3_k127_4886167_1	671143.DAMO_2457	1.154e-228	719.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS3_k127_4886167_22	589865.DaAHT2_2176	1.615e-31	129.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MKH2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS3_k127_4886167_30	1122236.KB905147_gene2131	1.225e-15	82.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KKBW@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4886167_34	1000565.METUNv1_03000	9.433e-07	62.0	COG0438@1|root,COG0457@1|root,COG1216@1|root,COG3914@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG1216@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,2KVEA@206389|Rhodocyclales	206389|Rhodocyclales	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_4886167_6	234267.Acid_2875	5.435e-105	355.0	COG3844@1|root,COG3844@2|Bacteria,3Y984@57723|Acidobacteria	57723|Acidobacteria	F	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS3_k127_4886167_14	1121033.AUCF01000005_gene5226	1.111e-55	214.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2U7KU@28211|Alphaproteobacteria,2JS2X@204441|Rhodospirillales	204441|Rhodospirillales	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
CMS3_k127_4886167_26	1123024.AUII01000039_gene1432	1.242e-25	111.0	COG0251@1|root,COG0251@2|Bacteria,2IHXH@201174|Actinobacteria,4E4CQ@85010|Pseudonocardiales	201174|Actinobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_4886167_20	1345023.M467_02510	2.388e-39	164.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3WEVJ@539002|Bacillales incertae sedis	91061|Bacilli	S	PFAM aldo keto reductase	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_4886167_32	1131269.AQVV01000044_gene1782	4.922e-07	60.0	COG2143@1|root,COG2143@2|Bacteria	2|Bacteria	O	COG2143 Thioredoxin-related protein	soxS	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	Thioredoxin_2,Thioredoxin_7
CMS3_k127_4886167_36	6500.XP_005107418.1	1.482e-06	62.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria	33208|Metazoa	S	inter-alpha-trypsin inhibitor heavy chain	ITIH5	-	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA,VWA_3
CMS3_k127_4886167_25	885272.JonanDRAFT_1446	4.284e-26	117.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,3TARX@508458|Synergistetes	508458|Synergistetes	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_4886167_5	237368.SCABRO_00027	1.571e-106	366.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_4886167_18	1196323.ALKF01000199_gene2514	4.673e-42	167.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4HC8Q@91061|Bacilli,26UNW@186822|Paenibacillaceae	91061|Bacilli	S	Phosphoesterase	ykuE	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS3_k127_4886167_35	479435.Kfla_2748	1.251e-06	63.0	COG3391@1|root,COG3391@2|Bacteria,2I2VV@201174|Actinobacteria,4DTEE@85009|Propionibacteriales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3
CMS3_k127_4886167_8	555079.Toce_1677	5.019e-91	310.0	COG3938@1|root,COG3938@2|Bacteria,1TQ61@1239|Firmicutes,2487S@186801|Clostridia,42HT1@68295|Thermoanaerobacterales	186801|Clostridia	G	Proline racemase	prdF	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
CMS3_k127_4886167_11	344747.PM8797T_20478	1.532e-81	289.0	COG0400@1|root,COG0400@2|Bacteria,2J2V6@203682|Planctomycetes	203682|Planctomycetes	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4886167_19	583355.Caka_2937	6.811e-42	178.0	COG3828@1|root,COG3828@2|Bacteria,46V1D@74201|Verrucomicrobia,3KA32@414999|Opitutae	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS3_k127_4886167_2	595460.RRSWK_04623	9.46e-190	628.0	COG1413@1|root,COG2010@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG3474@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K02305,ko:K08738	ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00529,M00595	R00294,R10151	RC02794,RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.10,3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2
CMS3_k127_4886167_4	756272.Plabr_2404	9.018e-141	460.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_4886167_28	1184267.A11Q_1128	1.319e-18	97.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,430W9@68525|delta/epsilon subdivisions,2MSZJ@213481|Bdellovibrionales,2WW2T@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
CMS3_k127_4886167_16	335543.Sfum_1413	4.833e-48	184.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_4886167_17	314345.SPV1_05552	6.869e-45	183.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria	1224|Proteobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS3_k127_4886167_12	1192034.CAP_8276	4.21e-69	264.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS3_k127_4886167_37	195250.CM001776_gene982	0.0003964	53.0	COG1266@1|root,COG1266@2|Bacteria,1G08W@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS3_k127_4886167_0	1121124.JNIX01000016_gene2071	0.0	1072.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2KG4I@204458|Caulobacterales	204458|Caulobacterales	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS3_k127_4886167_3	1168065.DOK_13169	4.64e-181	578.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,1RR9Q@1236|Gammaproteobacteria,1J7M1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Pfam:DUF1446	atuA	-	-	-	-	-	-	-	-	-	-	-	AtuA
CMS3_k127_4886167_23	1168065.DOK_13164	1.029e-28	134.0	2CIU6@1|root,32S8H@2|Bacteria,1MZTN@1224|Proteobacteria,1S6TT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4886167_10	1379270.AUXF01000006_gene74	2.589e-82	284.0	COG0280@1|root,COG0280@2|Bacteria,1ZT01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
CMS3_k127_4886167_33	713586.KB900536_gene2577	6.124e-07	62.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1WX6D@135613|Chromatiales	135613|Chromatiales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_4886167_29	1298867.AUES01000009_gene6018	1.943e-17	96.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,2TYMP@28211|Alphaproteobacteria,3JUCA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
CMS3_k127_4886167_9	671143.DAMO_2316	6.303e-85	291.0	COG0329@1|root,COG0329@2|Bacteria,2NP5Q@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS3_k127_4886167_27	264732.Moth_0936	6.351e-25	112.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,42GVS@68295|Thermoanaerobacterales	186801|Clostridia	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS3_k127_4886167_38	1296416.JACB01000004_gene1144	0.0006445	51.0	29XW7@1|root,30JNK@2|Bacteria,4PHYF@976|Bacteroidetes,1IG8N@117743|Flavobacteriia,2YKMF@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4886167_24	1089550.ATTH01000001_gene1600	1.882e-28	128.0	COG1612@1|root,COG1612@2|Bacteria,4PEIM@976|Bacteroidetes,1FJ6F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS3_k127_4886167_13	886293.Sinac_6888	3.829e-56	220.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS3_k127_4886167_7	204669.Acid345_2220	1.409e-93	331.0	COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_4886167_15	521674.Plim_0215	3.231e-51	202.0	COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes	203682|Planctomycetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_4886167_21	382464.ABSI01000005_gene1137	1.996e-34	136.0	COG2322@1|root,COG2322@2|Bacteria,46SZT@74201|Verrucomicrobia,2IUT2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF420
CMS3_k127_4886617_15	697282.Mettu_1098	1.326e-11	79.0	COG0726@1|root,COG2931@1|root,COG0726@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XFUS@135618|Methylococcales	135618|Methylococcales	QU	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4886617_2	1288963.ADIS_4732	5.758e-84	287.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_4886617_17	28444.JODQ01000006_gene348	4.832e-10	72.0	COG2374@1|root,COG3209@1|root,COG3534@1|root,COG2374@2|Bacteria,COG3209@2|Bacteria,COG3534@2|Bacteria,2IH7Z@201174|Actinobacteria,4EMIR@85012|Streptosporangiales	201174|Actinobacteria	M	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS3_k127_4886617_1	1449126.JQKL01000003_gene1810	8.823e-115	387.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS3_k127_4886617_13	1122221.JHVI01000012_gene927	1.788e-18	98.0	COG0589@1|root,COG0589@2|Bacteria,1WMQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_4886617_5	348824.LPU83_0758	6.049e-54	210.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1MUWG@1224|Proteobacteria,2U63K@28211|Alphaproteobacteria,4BA1V@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
CMS3_k127_4886617_7	765420.OSCT_0988	3.566e-44	169.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_4886617_3	373994.Riv7116_2726	3.521e-79	289.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G0A1@1117|Cyanobacteria,1HKN9@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM PAS domain S-box	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9
CMS3_k127_4886617_14	396588.Tgr7_3238	1.4e-12	78.0	COG0589@1|root,COG0589@2|Bacteria,1NBKV@1224|Proteobacteria,1SHMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
CMS3_k127_4886617_6	452637.Oter_0829	5.366e-45	173.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_4886617_16	1120947.ATUX01000007_gene798	6.261e-11	71.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4D431@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4886617_19	1205680.CAKO01000038_gene1859	2.73e-07	57.0	COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,2U8SB@28211|Alphaproteobacteria,2JYXA@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
CMS3_k127_4886617_10	330214.NIDE3757	5.497e-26	119.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_4886617_18	926690.KE386573_gene1677	6.022e-10	70.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_4886617_22	1280953.HOC_01626	0.0004177	51.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,2URZH@28211|Alphaproteobacteria,43XR7@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
CMS3_k127_4886617_11	456442.Mboo_2033	1.557e-22	104.0	COG0441@1|root,arCOG00401@2157|Archaea,2Y4U7@28890|Euryarchaeota,2NB51@224756|Methanomicrobia	224756|Methanomicrobia	J	Archaea-specific editing domain of threonyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-Thr_ED
CMS3_k127_4886617_20	643867.Ftrac_0495	1.662e-06	61.0	COG2374@1|root,COG4447@1|root,COG4733@1|root,COG4886@1|root,COG2374@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
CMS3_k127_4886617_12	401053.AciPR4_0317	1.888e-20	105.0	2E0CW@1|root,32VZR@2|Bacteria,3Y8VF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4886617_21	596151.DesfrDRAFT_2891	0.0001546	54.0	COG2755@1|root,COG2755@2|Bacteria,1NUF4@1224|Proteobacteria,435P9@68525|delta/epsilon subdivisions,2X9BM@28221|Deltaproteobacteria,2MA41@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4886617_0	886293.Sinac_6965	1.865e-154	507.0	COG0739@1|root,COG1506@1|root,COG3291@1|root,COG0739@2|Bacteria,COG1506@2|Bacteria,COG3291@2|Bacteria,2IYE5@203682|Planctomycetes	203682|Planctomycetes	E	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS3_k127_4886617_9	720554.Clocl_0436	7.369e-33	145.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_4886617_8	1206733.BAGC01000004_gene5871	2.723e-41	171.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4FW88@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknE	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pro_isomerase,SBP_bac_3
CMS3_k127_4886617_4	1403819.BATR01000183_gene6345	1.403e-76	269.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,DUF1080,HEAT_2,PmoA,ThuA
CMS3_k127_4906657_1	234267.Acid_2264	4.074e-188	603.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
CMS3_k127_4906657_0	234267.Acid_2265	3.005e-189	601.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_4906657_2	234267.Acid_2266	9.524e-186	607.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
CMS3_k127_4906657_4	452637.Oter_2220	3.483e-66	258.0	COG0251@1|root,COG0251@2|Bacteria,46V48@74201|Verrucomicrobia,3K8H7@414999|Opitutae	414999|Opitutae	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_4906657_3	653733.Selin_1844	1.035e-74	264.0	COG2876@1|root,COG2876@2|Bacteria	2|Bacteria	E	3-deoxy-7-phosphoheptulonate synthase activity	aroG-1	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS3_k127_4906657_6	1041930.Mtc_1685	0.0008132	49.0	COG5340@1|root,arCOG04793@2157|Archaea,2XVVB@28890|Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
CMS3_k127_4906657_5	1234364.AMSF01000061_gene2084	4.665e-21	106.0	COG0793@1|root,COG0793@2|Bacteria,1N4T9@1224|Proteobacteria,1SE36@1236|Gammaproteobacteria,1X70X@135614|Xanthomonadales	135614|Xanthomonadales	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ_2
CMS3_k127_4910330_0	1123508.JH636441_gene3252	1.54e-115	380.0	COG0329@1|root,COG0329@2|Bacteria,2IY4I@203682|Planctomycetes	203682|Planctomycetes	EM	Belongs to the DapA family	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS3_k127_4910330_1	575540.Isop_1244	1.969e-110	366.0	COG3622@1|root,COG3622@2|Bacteria,2IYNY@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_4910330_2	398767.Glov_2994	1.794e-86	312.0	2DUAU@1|root,33PQN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4910330_4	1713.JOFV01000002_gene709	8.351e-06	59.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	CAP,Laminin_G_3
CMS3_k127_4910330_3	981384.AEYW01000001_gene1714	1.275e-12	78.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TR41@28211|Alphaproteobacteria,4NDQG@97050|Ruegeria	28211|Alphaproteobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
CMS3_k127_4941004_6	1458427.BAWN01000021_gene1306	1.344e-23	113.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS3_k127_4941004_7	269800.Tfu_0117	4.68e-06	54.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4EG3J@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, cAMP Regulatory protein	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS3_k127_4941004_5	756067.MicvaDRAFT_4986	7.008e-29	130.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS3_k127_4941004_2	344747.PM8797T_06325	2.99e-121	441.0	COG2133@1|root,COG2133@2|Bacteria,2IWVG@203682|Planctomycetes	203682|Planctomycetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4941004_0	1210884.HG799464_gene10641	6.694e-245	824.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPU@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
CMS3_k127_4941004_1	314230.DSM3645_23496	2.382e-183	599.0	COG3119@1|root,COG3119@2|Bacteria,2IXP1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_4941004_3	1235279.C772_02264	1.642e-61	233.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,26D4W@186818|Planococcaceae	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmCD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS3_k127_4941004_4	1396141.BATP01000003_gene5168	2.216e-49	200.0	2EKQJ@1|root,33EEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_496054_3	886293.Sinac_7220	3.63e-80	296.0	COG0642@1|root,COG2205@2|Bacteria,2IZC4@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_496054_4	215803.DB30_7771	4.15e-70	261.0	COG0745@1|root,COG0745@2|Bacteria,1PEJ3@1224|Proteobacteria,43A03@68525|delta/epsilon subdivisions,2X9R1@28221|Deltaproteobacteria,2YWP7@29|Myxococcales	28221|Deltaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_496054_6	886293.Sinac_7218	1.942e-68	247.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_496054_2	886293.Sinac_1816	1.455e-89	325.0	COG2304@1|root,COG2304@2|Bacteria,2IY1T@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA,VWA_3
CMS3_k127_496054_1	1229780.BN381_100013	1.459e-98	327.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,3UXE8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_496054_7	945713.IALB_1400	1.162e-26	128.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	rtxA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	ASH,CBM_2,Calx-beta,DUF4214,FlgD_ig,HemolysinCabind,SdrD_B
CMS3_k127_496054_0	945713.IALB_0608	2.645e-143	479.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CMS3_k127_496054_5	1237149.C900_01007	1.464e-69	252.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
CMS3_k127_4972980_30	1394178.AWOO02000013_gene7866	7.353e-08	64.0	COG3485@1|root,COG3485@2|Bacteria,2GMGM@201174|Actinobacteria,4EH8C@85012|Streptosporangiales	201174|Actinobacteria	Q	Protocatechuate 3,4-dioxygenase beta subunit N terminal	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
CMS3_k127_4972980_25	886293.Sinac_2556	6.34e-20	101.0	COG0526@1|root,COG1331@1|root,COG0526@2|Bacteria,COG1331@2|Bacteria,2J28Y@203682|Planctomycetes	203682|Planctomycetes	CO	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_4972980_6	1007104.SUS17_1119	1.359e-113	402.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2TR3D@28211|Alphaproteobacteria,2K0NS@204457|Sphingomonadales	204457|Sphingomonadales	E	PFAM Serine dehydratase alpha chain	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CMS3_k127_4972980_16	344747.PM8797T_25391	3.654e-64	237.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_4972980_14	867845.KI911784_gene2277	6.61e-70	262.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_4972980_12	497964.CfE428DRAFT_1721	3.259e-79	288.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_4972980_15	643562.Daes_3051	9.238e-67	235.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,42SRU@68525|delta/epsilon subdivisions,2WPAI@28221|Deltaproteobacteria,2MBEQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Peptidase C26	guaA2	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CMS3_k127_4972980_28	404589.Anae109_0911	3.109e-08	67.0	COG0793@1|root,COG3485@1|root,COG0793@2|Bacteria,COG3485@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_4972980_1	1379270.AUXF01000001_gene2749	2.894e-214	691.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_4972980_2	1283300.ATXB01000001_gene1800	3.854e-157	509.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XDMT@135618|Methylococcales	1236|Gammaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_4972980_21	661478.OP10G_3682	1.889e-42	164.0	COG5553@1|root,COG5553@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CDO_I
CMS3_k127_4972980_5	1385513.N780_06200	7.011e-120	398.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,2Y8N8@289201|Pontibacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_4972980_0	1192034.CAP_4888	1.069e-310	964.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,2YX5D@29|Myxococcales	28221|Deltaproteobacteria	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_4972980_13	1122971.BAME01000091_gene5612	2.451e-74	278.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,2FPXP@200643|Bacteroidia,22ZQH@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_4972980_27	661478.OP10G_0106	5.388e-14	80.0	COG0597@1|root,COG0597@2|Bacteria	2|Bacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_4972980_7	96561.Dole_2472	6.927e-103	355.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42YHE@68525|delta/epsilon subdivisions,2WUJ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_4972980_10	234267.Acid_7437	2.513e-92	333.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,3Y79C@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
CMS3_k127_4972980_26	711393.AYRX01000067_gene2295	7.933e-17	94.0	COG0438@1|root,COG0438@2|Bacteria,2IRB6@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4
CMS3_k127_4972980_31	497964.CfE428DRAFT_6042	7.798e-06	59.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYQ@74201|Verrucomicrobia	2|Bacteria	CG	Cytochrome c	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Cytochrom_C,GSDH,HEAT_2,HEAT_PBS,S1,ThuA
CMS3_k127_4972980_19	502025.Hoch_4583	3.196e-49	185.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria,2Z31F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS3_k127_4972980_29	1227349.C170_15815	7.123e-08	61.0	COG1652@1|root,COG1652@2|Bacteria,1V4J4@1239|Firmicutes,4IUF8@91061|Bacilli,276WM@186822|Paenibacillaceae	91061|Bacilli	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_4972980_18	1305737.JAFX01000001_gene1212	1.751e-52	209.0	COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,47N4V@768503|Cytophagia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_4972980_24	713586.KB900536_gene873	2.058e-24	120.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
CMS3_k127_4972980_11	383372.Rcas_3355	7.713e-81	291.0	COG1364@1|root,COG1364@2|Bacteria,2G64K@200795|Chloroflexi,37529@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	-	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS3_k127_4972980_22	653733.Selin_2227	9.887e-40	158.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argH	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K00619,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0946	ASL_C2,Acetyltransf_1,Lyase_1
CMS3_k127_4972980_4	221988.MS0237	1.15e-146	496.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,1Y79S@135625|Pasteurellales	135625|Pasteurellales	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS3_k127_4972980_3	4006.Lus10012800	2.384e-149	497.0	COG0137@1|root,KOG1706@2759|Eukaryota,37QUX@33090|Viridiplantae,3G8Y6@35493|Streptophyta,4JEKX@91835|fabids	35493|Streptophyta	E	Argininosuccinate synthase	-	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS3_k127_4972980_8	1382359.JIAL01000001_gene2594	9.185e-99	332.0	COG0078@1|root,COG0078@2|Bacteria,3Y3WW@57723|Acidobacteria,2JHPN@204432|Acidobacteriia	204432|Acidobacteriia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_4972980_9	401053.AciPR4_2054	5.55e-93	321.0	COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria,2JI27@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_4972980_20	1304275.C41B8_11688	2.88e-48	188.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the ATP-dependent phosphorylation of N-acetyl- L-glutamate	argB	GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.7.2.8	ko:K00930,ko:K22478	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00259,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255	AA_kinase,NAT
CMS3_k127_4972980_23	1150626.PHAMO_220067	1.041e-32	130.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2JQ0D@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_4975427_4	595460.RRSWK_00473	3.73e-13	79.0	2C73B@1|root,330Z7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
CMS3_k127_4975427_0	391625.PPSIR1_06551	8.677e-61	223.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
CMS3_k127_4975427_1	1123228.AUIH01000006_gene2193	9.811e-55	201.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,1S2TG@1236|Gammaproteobacteria,1XJCR@135619|Oceanospirillales	135619|Oceanospirillales	S	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS3_k127_4975427_2	530564.Psta_3753	7.766e-22	103.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_4975427_5	72004.XP_005911905.1	2.622e-12	81.0	KOG1947@1|root,KOG1947@2759|Eukaryota,38EZ4@33154|Opisthokonta,3BEYN@33208|Metazoa,3D0ZV@33213|Bilateria,486YW@7711|Chordata,490QW@7742|Vertebrata,3JFSV@40674|Mammalia	33208|Metazoa	S	ubiquitin-protein transferase activity	FBXL14	GO:0000151,GO:0000209,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019005,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0031146,GO:0031461,GO:0032446,GO:0032991,GO:0036211,GO:0043161,GO:0043170,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051603,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234	-	ko:K10280	-	-	-	-	ko00000,ko04121	-	-	-	F-box,F-box-like,LRR_6
CMS3_k127_4975427_3	298654.FraEuI1c_4788	4.045e-16	88.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS3_k127_5001816_1	526227.Mesil_0657	2.448e-64	237.0	COG3055@1|root,COG3055@2|Bacteria,1WK3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
CMS3_k127_5001816_2	62977.ACIAD2142	2.895e-38	161.0	2EYSQ@1|root,33RZZ@2|Bacteria,1NRGW@1224|Proteobacteria,1SME0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001816_3	483219.LILAB_29000	1.036e-31	131.0	COG1716@1|root,COG1716@2|Bacteria,1N47K@1224|Proteobacteria,434WB@68525|delta/epsilon subdivisions,2WZ7A@28221|Deltaproteobacteria,2Z1HC@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4123)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4123
CMS3_k127_5001816_0	935567.JAES01000001_gene2175	3.172e-92	313.0	COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,1S5SD@1236|Gammaproteobacteria,1X617@135614|Xanthomonadales	135614|Xanthomonadales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
CMS3_k127_50041_2	575540.Isop_1644	3.788e-238	767.0	COG0265@1|root,COG3266@1|root,COG4447@1|root,COG0265@2|Bacteria,COG3266@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4,3.4.21.107	ko:K01179,ko:K04771	ko00500,ko01100,ko01503,ko02020,map00500,map01100,map01503,map02020	M00728	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	GH5,GH9	-	PDZ_2,Sortilin-Vps10,Trypsin_2
CMS3_k127_50041_4	234267.Acid_5051	7.163e-211	690.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CMS3_k127_50041_12	1123274.KB899406_gene1253	8.377e-90	315.0	COG4690@1|root,COG4690@2|Bacteria,2J5N0@203691|Spirochaetes	203691|Spirochaetes	E	Dipeptidase	-	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
CMS3_k127_50041_9	240016.ABIZ01000001_gene875	2.741e-110	375.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_50041_18	1392498.JQLH01000001_gene1805	6.866e-22	113.0	COG2706@1|root,COG2706@2|Bacteria,4NMAT@976|Bacteroidetes,1I1UW@117743|Flavobacteriia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_50041_22	566461.SSFG_06274	0.0007396	53.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria	201174|Actinobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Beta-lactamase,Condensation,PP-binding,Thioesterase
CMS3_k127_50041_21	266940.Krad_0406	3.789e-09	71.0	COG1595@1|root,COG1595@2|Bacteria,2IMV5@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_50041_13	351348.Maqu_0874	2.189e-77	295.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,4642R@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02481,ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_50041_16	1266908.AQPB01000034_gene656	5.584e-42	174.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1SZ84@1236|Gammaproteobacteria,1WXUW@135613|Chromatiales	135613|Chromatiales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_50041_14	935567.JAES01000026_gene1342	1.914e-54	201.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,1X5X0@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_50041_7	402777.KB235903_gene1618	7.397e-124	414.0	COG0463@1|root,COG0463@2|Bacteria,1G4BG@1117|Cyanobacteria,1H8D9@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_50041_1	886293.Sinac_1153	9.861e-282	891.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
CMS3_k127_50041_5	886293.Sinac_1154	4.718e-177	584.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_50041_6	886293.Sinac_1155	1.219e-140	481.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
CMS3_k127_50041_17	204669.Acid345_3543	3.976e-34	151.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
CMS3_k127_50041_19	497964.CfE428DRAFT_6333	2.245e-17	97.0	COG2127@1|root,COG2127@2|Bacteria,46T8N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS3_k127_50041_20	457421.CBFG_04536	2.561e-13	82.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,26AFE@186813|unclassified Clostridiales	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS3_k127_50041_15	756272.Plabr_0308	2.049e-48	200.0	COG2947@1|root,COG2947@2|Bacteria,2IZM3@203682|Planctomycetes	203682|Planctomycetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS3_k127_50041_0	649638.Trad_0147	0.0	1163.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_50041_11	1242864.D187_000932	7.01e-95	328.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria	1224|Proteobacteria	G	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS3_k127_50041_8	76114.ebA3150	1.932e-117	412.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2W1Q4@28216|Betaproteobacteria,2KXXH@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_50041_3	909613.UO65_1172	1.109e-237	749.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria,4DXF9@85010|Pseudonocardiales	201174|Actinobacteria	C	ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_5005146_1	247490.KSU1_D0957	9.35e-89	306.0	COG0232@1|root,COG0232@2|Bacteria,2IX8F@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS3_k127_5005146_2	290397.Adeh_1771	6.978e-12	78.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5005146_3	344747.PM8797T_18559	9.452e-05	55.0	COG1331@1|root,COG1331@2|Bacteria,2J18M@203682|Planctomycetes	203682|Planctomycetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CMS3_k127_5005146_0	497964.CfE428DRAFT_5010	1.473e-123	401.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5015378_2	886293.Sinac_2445	3.993e-129	427.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,M60-like_N,PSCyt1,PSCyt2,PSD1,Peptidase_M60
CMS3_k127_5015378_1	595460.RRSWK_02494	2.982e-194	621.0	COG3119@1|root,COG3119@2|Bacteria,2J51U@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_5015378_0	886293.Sinac_1210	2.669e-268	863.0	COG2010@1|root,COG2010@2|Bacteria,2IXBQ@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_5015378_5	243272.MARTH_orf030	0.0006667	44.0	COG3118@1|root,COG3118@2|Bacteria,3WTYZ@544448|Tenericutes	544448|Tenericutes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS3_k127_5015378_4	1120956.JHZK01000011_gene1213	5.993e-42	166.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_15,Methyltransf_25,NodS
CMS3_k127_5015378_3	243233.MCA2126	3.478e-45	179.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RXGH@1236|Gammaproteobacteria,1XG2N@135618|Methylococcales	135618|Methylococcales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
CMS3_k127_5023784_0	1239962.C943_04599	8.995e-50	198.0	COG0823@1|root,COG0823@2|Bacteria,4PI3V@976|Bacteroidetes,47VXF@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS3_k127_5035222_4	637905.SVI_3429	5.642e-107	355.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,1RNFV@1236|Gammaproteobacteria,2QAM1@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM ornithine cyclodeaminase mu-crystallin	ocd	-	1.5.1.1,1.5.1.49,1.5.1.51,4.3.1.12	ko:K01750,ko:K19742,ko:K19743,ko:K21721	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS3_k127_5035222_0	1250232.JQNJ01000001_gene2191	9.001e-265	829.0	COG2936@1|root,COG2936@2|Bacteria,4NHGT@976|Bacteroidetes,1HYGE@117743|Flavobacteriia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_5035222_2	1249627.D779_1905	5.858e-160	515.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales	135613|Chromatiales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS3_k127_5035222_6	1232410.KI421418_gene2433	1.095e-93	339.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,42SR8@68525|delta/epsilon subdivisions,2WPN0@28221|Deltaproteobacteria,43U8D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
CMS3_k127_5035222_7	1394178.AWOO02000085_gene985	6.567e-71	263.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4EH2R@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,BPD_transp_1,CBS
CMS3_k127_5035222_5	314278.NB231_13646	1.013e-98	353.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,1RQ1F@1236|Gammaproteobacteria,1WX4F@135613|Chromatiales	135613|Chromatiales	P	ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
CMS3_k127_5035222_1	756272.Plabr_3753	2.102e-238	757.0	COG3119@1|root,COG3119@2|Bacteria,2J2K4@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_5035222_3	1205680.CAKO01000002_gene2183	7.616e-115	387.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,2JQU5@204441|Rhodospirillales	204441|Rhodospirillales	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS3_k127_5041666_0	886293.Sinac_6967	1.425e-215	697.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_5041666_1	886293.Sinac_6968	2.795e-179	577.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CMS3_k127_5075137_9	220664.PFL_3030	2.785e-20	104.0	28M8C@1|root,2ZAMI@2|Bacteria,1R981@1224|Proteobacteria,1SMPK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5075137_2	1267534.KB906756_gene250	1.886e-137	445.0	COG1899@1|root,COG1899@2|Bacteria,3Y5EW@57723|Acidobacteria,2JJNA@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS3_k127_5075137_10	448385.sce5359	8.892e-14	86.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_5075137_11	1178825.ALIH01000013_gene512	2.279e-07	62.0	COG1076@1|root,COG1076@2|Bacteria,4NF1B@976|Bacteroidetes,1HYUI@117743|Flavobacteriia	976|Bacteroidetes	O	DnaJ domain protein	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
CMS3_k127_5075137_6	309807.SRU_2280	2.918e-38	147.0	COG1765@1|root,COG1765@2|Bacteria,4NQ66@976|Bacteroidetes	976|Bacteroidetes	O	redox protein regulator of disulfide bond formation	osmC	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_5075137_5	187272.Mlg_2129	3.096e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,1X0Z2@135613|Chromatiales	135613|Chromatiales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5075137_4	574966.KB898648_gene882	2.681e-76	282.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1XJGR@135619|Oceanospirillales	135619|Oceanospirillales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_5075137_7	314230.DSM3645_26074	4.739e-34	152.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_5075137_0	314230.DSM3645_26079	5e-324	1026.0	COG0841@1|root,COG0841@2|Bacteria,2IY0K@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_5075137_1	1340493.JNIF01000004_gene1069	8.648e-148	476.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS3_k127_5075137_8	266264.Rmet_4637	4.55e-25	108.0	COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,2VVVJ@28216|Betaproteobacteria,1KHJV@119060|Burkholderiaceae	28216|Betaproteobacteria	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
CMS3_k127_5075137_3	861299.J421_3663	7.087e-119	395.0	COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_5109536_1	869210.Marky_0033	9.744e-89	310.0	COG0436@1|root,COG0436@2|Bacteria,1WIMB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5109536_0	391625.PPSIR1_11943	2.257e-91	342.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CMS3_k127_5109536_2	1500897.JQNA01000002_gene1348	7.699e-72	272.0	COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria	1224|Proteobacteria	S	HD superfamily	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_5109536_5	215803.DB30_7967	0.0009435	52.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria,2YYWS@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_5109536_3	1382356.JQMP01000003_gene2572	1.513e-49	194.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,27Y1R@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_5109536_4	2002.JOEQ01000004_gene3047	1.298e-05	58.0	COG0438@1|root,COG0438@2|Bacteria,2GK9J@201174|Actinobacteria,4EHRN@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5164917_23	203124.Tery_1672	9.485e-60	222.0	COG2755@1|root,COG2755@2|Bacteria,1G2XP@1117|Cyanobacteria,1H81W@1150|Oscillatoriales	1117|Cyanobacteria	E	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX
CMS3_k127_5164917_8	243090.RB5763	2.731e-110	371.0	COG2133@1|root,COG2133@2|Bacteria,2IZH6@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_5164917_4	379066.GAU_2028	4.935e-188	617.0	COG2936@1|root,COG2936@2|Bacteria,1ZTD6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_5164917_33	314345.SPV1_07269	7.571e-32	131.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057	-	ko:K03406,ko:K06886	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Bac_globin
CMS3_k127_5164917_3	1122939.ATUD01000001_gene577	2.873e-195	647.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5164917_25	1192034.CAP_7171	1.61e-53	197.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2Z32M@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS3_k127_5164917_11	1185876.BN8_01559	8.39e-96	322.0	COG5395@1|root,COG5395@2|Bacteria,4NG1V@976|Bacteroidetes,47XVM@768503|Cytophagia	976|Bacteroidetes	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
CMS3_k127_5164917_50	1142394.PSMK_06260	1.063e-06	61.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_5164917_6	521674.Plim_4022	2.949e-149	484.0	COG0823@1|root,COG0823@2|Bacteria,2J1XG@203682|Planctomycetes	203682|Planctomycetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5164917_12	349521.HCH_03183	9.187e-94	335.0	COG1171@1|root,COG1171@2|Bacteria,1NN0Z@1224|Proteobacteria,1RMV6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Dehydratase	-	-	4.3.1.17,4.3.1.19	ko:K17989	ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00590,R00996	RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_5164917_20	1296415.JACC01000025_gene1691	5.367e-63	237.0	2DQMZ@1|root,337PX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5164917_35	1120966.AUBU01000013_gene372	2.772e-26	119.0	COG0500@1|root,COG2226@2|Bacteria,4NYCJ@976|Bacteroidetes,47U3P@768503|Cytophagia	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_5164917_17	929562.Emtol_0413	6.543e-86	297.0	2DB9P@1|root,2Z7Y1@2|Bacteria,4NHQN@976|Bacteroidetes,47M0R@768503|Cytophagia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_5164917_44	558152.IQ37_10635	5.867e-15	87.0	COG2350@1|root,COG2350@2|Bacteria,4NRC1@976|Bacteroidetes,1I447@117743|Flavobacteriia,3ZPYB@59732|Chryseobacterium	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_5164917_18	471854.Dfer_1903	3.757e-81	278.0	COG5285@1|root,COG5285@2|Bacteria,4NMJG@976|Bacteroidetes,47U43@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_5164917_26	323261.Noc_1728	8.827e-51	187.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Lysophospholipase	ynbC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Methyltransf_20
CMS3_k127_5164917_47	631362.Thi970DRAFT_01175	2.592e-08	65.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X2F8@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5164917_41	983920.Y88_2821	3.713e-20	104.0	COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2K0QK@204457|Sphingomonadales	204457|Sphingomonadales	S	to the N-terminal domain of Lon protease	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
CMS3_k127_5164917_9	1160707.AJIK01000006_gene1012	3.454e-110	369.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,26E01@186818|Planococcaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_5164917_24	765177.Desmu_1233	1.277e-57	212.0	COG0024@1|root,arCOG01001@2157|Archaea,2XPVJ@28889|Crenarchaeota	28889|Crenarchaeota	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS3_k127_5164917_5	68170.KL590470_gene11034	3.64e-168	539.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,4DXR1@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_5164917_29	204669.Acid345_3253	7.454e-46	173.0	COG1607@1|root,COG1607@2|Bacteria,3Y53T@57723|Acidobacteria,2JMAX@204432|Acidobacteriia	204432|Acidobacteriia	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_5164917_49	4577.GRMZM2G172230_P01	4.778e-08	62.0	COG0542@1|root,KOG1051@2759|Eukaryota,37IAE@33090|Viridiplantae,3GETK@35493|Streptophyta,3KRTX@4447|Liliopsida,3I94U@38820|Poales	35493|Streptophyta	O	Belongs to the ClpA ClpB family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009628,GO:0009941,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0031967,GO:0031975,GO:0033554,GO:0034214,GO:0034605,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046983,GO:0047484,GO:0048518,GO:0048583,GO:0048584,GO:0050789,GO:0050896,GO:0051259,GO:0051716,GO:0065003,GO:0065007,GO:0071840,GO:0080134,GO:1901000,GO:1901002,GO:1902584,GO:2000070	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS3_k127_5164917_16	935948.KE386494_gene372	1.511e-90	320.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia,42FE6@68295|Thermoanaerobacterales	186801|Clostridia	O	COGs COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS3_k127_5164917_42	1382304.JNIL01000001_gene926	4.907e-20	97.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,278I1@186823|Alicyclobacillaceae	91061|Bacilli	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS3_k127_5164917_2	1313301.AUGC01000001_gene1672	1.61e-195	634.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS3_k127_5164917_36	1242864.D187_008068	1.271e-25	118.0	COG0586@1|root,COG0586@2|Bacteria,1R6V4@1224|Proteobacteria,42XP4@68525|delta/epsilon subdivisions,2WT5P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_5164917_28	237368.SCABRO_02955	4.088e-46	179.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5164917_0	344747.PM8797T_18419	5.094e-254	816.0	COG0654@1|root,COG0654@2|Bacteria,2IWSD@203682|Planctomycetes	203682|Planctomycetes	CH	xanthan lyase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS3_k127_5164917_21	1123508.JH636444_gene5205	1.059e-61	242.0	COG4099@1|root,COG4099@2|Bacteria,2IZFN@203682|Planctomycetes	203682|Planctomycetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS3_k127_5164917_32	96561.Dole_2126	4.403e-32	133.0	COG0745@1|root,COG0745@2|Bacteria,1MZ7D@1224|Proteobacteria,42VVV@68525|delta/epsilon subdivisions,2WRBW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_5164917_10	448385.sce6964	4.694e-102	355.0	COG4191@1|root,COG4191@2|Bacteria,1R95R@1224|Proteobacteria,42PEG@68525|delta/epsilon subdivisions,2WM8J@28221|Deltaproteobacteria,2YU43@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS3_k127_5164917_7	1254432.SCE1572_40930	1.281e-142	473.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P6D@68525|delta/epsilon subdivisions,2WM1P@28221|Deltaproteobacteria,2YUD4@29|Myxococcales	28221|Deltaproteobacteria	T	DNA-binding response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5164917_15	502025.Hoch_0451	5.616e-92	343.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_5164917_13	290397.Adeh_2667	1.7e-93	346.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Pyr_redox_3
CMS3_k127_5164917_14	1408473.JHXO01000005_gene1865	1.019e-92	328.0	COG0484@1|root,COG0484@2|Bacteria,4NPS0@976|Bacteroidetes,2FXKU@200643|Bacteroidia	976|Bacteroidetes	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5164917_19	1121875.KB907548_gene1476	1.451e-74	284.0	COG5553@1|root,COG5553@2|Bacteria,4NJMB@976|Bacteroidetes,1I0CQ@117743|Flavobacteriia	976|Bacteroidetes	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5164917_52	342113.DM82_5178	2.903e-06	59.0	COG3209@1|root,COG3209@2|Bacteria,1R5DQ@1224|Proteobacteria,2VMRN@28216|Betaproteobacteria,1K430@119060|Burkholderiaceae	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5164917_45	1128427.KB904821_gene628	6.251e-15	86.0	COG1404@1|root,COG1520@1|root,COG2304@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2304@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
CMS3_k127_5164917_1	861299.J421_6085	3.761e-240	763.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSND@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_5164917_51	518766.Rmar_1153	1.29e-06	61.0	COG1216@1|root,COG1216@2|Bacteria,4NXX6@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS3_k127_5164917_34	649747.HMPREF0083_04295	3.545e-29	132.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4HCG2@91061|Bacilli,26TIW@186822|Paenibacillaceae	91061|Bacilli	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_5164917_40	641491.DND132_0102	7.778e-24	119.0	COG0535@1|root,COG0535@2|Bacteria,1Q6UY@1224|Proteobacteria,435MF@68525|delta/epsilon subdivisions,2X00D@28221|Deltaproteobacteria,2M9DM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_5164917_39	243265.plu4024	1.481e-24	119.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS3_k127_5164917_38	1379698.RBG1_1C00001G0682	9.096e-25	119.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS3_k127_5164917_55	330214.NIDE1394	0.0006272	49.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,TPR_19,TPR_8,Transglut_core
CMS3_k127_5164917_22	44060.JODL01000015_gene5215	5.324e-61	232.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS3_k127_5164917_48	309801.trd_0659	2.611e-08	65.0	COG0859@1|root,COG0859@2|Bacteria,2G6JB@200795|Chloroflexi,27XRD@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_5164917_53	1128427.KB904821_gene4607	6.113e-06	59.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,FtsX
CMS3_k127_5164917_31	1120970.AUBZ01000003_gene174	2.774e-44	181.0	2CKCQ@1|root,31FHN@2|Bacteria,1RKED@1224|Proteobacteria,1SKDY@1236|Gammaproteobacteria,46A4R@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5164917_37	1211815.CBYP010000028_gene1114	8.342e-25	115.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4ERMB@85013|Frankiales	201174|Actinobacteria	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_5164917_46	448385.sce1844	6.822e-14	86.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_5164917_43	42099.EPrPV00000021227	3.108e-16	93.0	COG0457@1|root,KOG1124@2759|Eukaryota,1MGBT@121069|Pythiales	121069|Pythiales	S	Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736
CMS3_k127_5164917_27	566466.NOR53_2748	8.178e-47	182.0	COG3568@1|root,COG3568@2|Bacteria,1RJZP@1224|Proteobacteria,1TH72@1236|Gammaproteobacteria,1JABN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_5202993_1	313628.LNTAR_07229	8.119e-148	487.0	COG3119@1|root,COG3119@2|Bacteria	313628.LNTAR_07229|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5202993_2	709986.Deima_1972	1.133e-138	481.0	COG2252@1|root,COG2252@2|Bacteria,1WM47@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
CMS3_k127_5202993_4	575540.Isop_1648	3.402e-30	136.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_5202993_0	1122939.ATUD01000001_gene577	4.382e-185	616.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5202993_3	1284352.AOIG01000013_gene3550	9.068e-51	201.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Cohesin,Invasin_D3,SLH
CMS3_k127_5249939_1	1122179.KB890442_gene1152	2.375e-22	105.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_5249939_2	345219.Bcoa_1107	8.165e-15	89.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5249939_0	318996.AXAZ01000064_gene5665	1.323e-26	127.0	COG3227@1|root,COG4870@1|root,COG3227@2|Bacteria,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.24.25	ko:K08604,ko:K20276	ko02024,ko05110,ko05111,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_6,ChW,He_PIG,Peptidase_C1,Peptidase_M4,Peptidase_M4_C
CMS3_k127_5253475_22	215803.DB30_2544	0.0001508	50.0	COG3521@1|root,COG3521@2|Bacteria,1PEH5@1224|Proteobacteria,436QF@68525|delta/epsilon subdivisions,2WY4G@28221|Deltaproteobacteria,2YW11@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
CMS3_k127_5253475_8	1267535.KB906767_gene921	2.223e-81	292.0	COG3522@1|root,COG3522@2|Bacteria,3Y3ZF@57723|Acidobacteria,2JKHI@204432|Acidobacteriia	204432|Acidobacteriia	S	type VI secretion protein, VC_A0114 family	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
CMS3_k127_5253475_18	1380387.JADM01000010_gene3981	4.149e-25	113.0	COG3455@1|root,COG3455@2|Bacteria,1NMWP@1224|Proteobacteria,1S3HZ@1236|Gammaproteobacteria,1XPWA@135619|Oceanospirillales	135619|Oceanospirillales	S	Type VI secretion system protein DotU	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
CMS3_k127_5253475_6	330214.NIDE1973	6.082e-101	370.0	COG3523@1|root,COG3523@2|Bacteria,3J159@40117|Nitrospirae	40117|Nitrospirae	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
CMS3_k127_5253475_20	338963.Pcar_2812	7.031e-14	83.0	COG3913@1|root,COG3913@2|Bacteria	2|Bacteria	T	Uncharacterized protein conserved in bacteria (DUF2094)	-	-	-	ko:K11890,ko:K11910	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF2094
CMS3_k127_5253475_15	243365.CV_3963	2.096e-40	163.0	COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,2VN8Y@28216|Betaproteobacteria,2KPWU@206351|Neisseriales	206351|Neisseriales	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N
CMS3_k127_5253475_13	438753.AZC_2599	4.068e-44	168.0	COG3516@1|root,COG3516@2|Bacteria,1R9Y7@1224|Proteobacteria,2TVU7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	impB	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
CMS3_k127_5253475_1	1123242.JH636435_gene1609	2.339e-175	562.0	COG3517@1|root,COG3517@2|Bacteria,2IXI1@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, EvpB VC_A0108 family	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
CMS3_k127_5253475_14	1265505.ATUG01000001_gene4610	2.907e-43	164.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,42XEQ@68525|delta/epsilon subdivisions,2WTD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
CMS3_k127_5253475_17	1121861.KB899910_gene670	1.059e-30	138.0	COG4455@1|root,COG4455@2|Bacteria,1MWHI@1224|Proteobacteria,2TX82@28211|Alphaproteobacteria,2JVHP@204441|Rhodospirillales	204441|Rhodospirillales	S	ImpE protein	-	-	-	ko:K11898	-	-	-	-	ko00000,ko02044	-	-	-	ImpE,TPR_19
CMS3_k127_5253475_19	886293.Sinac_2408	2.47e-16	85.0	COG3518@1|root,COG3518@2|Bacteria,2J0UC@203682|Planctomycetes	203682|Planctomycetes	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
CMS3_k127_5253475_4	330214.NIDE1983	1.971e-126	428.0	COG3519@1|root,COG3519@2|Bacteria,3J114@40117|Nitrospirae	40117|Nitrospirae	S	Pfam:T6SS_VipB	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
CMS3_k127_5253475_10	886293.Sinac_2406	8.524e-57	226.0	COG3520@1|root,COG3520@2|Bacteria,2IZ33@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion protein, VC_A0111 family	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
CMS3_k127_5253475_0	886293.Sinac_2420	0.0	1036.0	COG0542@1|root,COG0542@2|Bacteria,2IWVE@203682|Planctomycetes	203682|Planctomycetes	O	TIGRFAM type VI secretion ATPase, ClpV1 family	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
CMS3_k127_5253475_2	1265505.ATUG01000001_gene4608	3.314e-171	565.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42Q4M@68525|delta/epsilon subdivisions,2WKZN@28221|Deltaproteobacteria,2MK30@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
CMS3_k127_5253475_11	886293.Sinac_4694	7.117e-56	215.0	COG1657@1|root,COG1657@2|Bacteria,2IYCT@203682|Planctomycetes	203682|Planctomycetes	I	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_5253475_9	575540.Isop_0047	3.005e-66	254.0	COG4232@1|root,COG4232@2|Bacteria,2IXJF@203682|Planctomycetes	203682|Planctomycetes	CO	Cytochrome c biogenesis protein transmembrane region	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
CMS3_k127_5253475_21	1406840.Q763_03545	4.44e-05	55.0	COG0428@1|root,COG0428@2|Bacteria,4NG1R@976|Bacteroidetes,1HYRJ@117743|Flavobacteriia,2NT5S@237|Flavobacterium	976|Bacteroidetes	P	ZIP family metal transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
CMS3_k127_5253475_3	682795.AciX8_1188	3.315e-136	447.0	COG0183@1|root,COG0183@2|Bacteria,3Y3SQ@57723|Acidobacteria,2JHU2@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_5253475_5	861299.J421_3002	1.511e-103	346.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS3_k127_5253475_7	1002809.SSIL_3404	1.784e-89	321.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,26DW2@186818|Planococcaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, middle domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5253475_12	1265845.PWEIH_11170	4.006e-54	205.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,26JCA@186820|Listeriaceae	91061|Bacilli	OU	Signal peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS3_k127_5253475_16	1449126.JQKL01000002_gene1595	2.202e-40	167.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_5253693_8	1123242.JH636435_gene944	4.657e-84	312.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_5253693_5	521674.Plim_3506	4.356e-121	424.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_5253693_1	886293.Sinac_0925	8.858e-142	468.0	COG3119@1|root,COG3119@2|Bacteria,2IXPB@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_5253693_7	314230.DSM3645_26034	1.423e-85	293.0	COG0329@1|root,COG0329@2|Bacteria,2J23B@203682|Planctomycetes	203682|Planctomycetes	H	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
CMS3_k127_5253693_0	497964.CfE428DRAFT_0703	1.065e-148	504.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K02305,ko:K07152	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko03029	3.D.4.10	-	-	Cytochrom_C,SCO1-SenC
CMS3_k127_5253693_3	886293.Sinac_5788	1.801e-131	441.0	COG2133@1|root,COG2133@2|Bacteria,2IWS3@203682|Planctomycetes	203682|Planctomycetes	G	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5253693_17	502025.Hoch_2738	2.055e-05	59.0	2C9M1@1|root,2ZSUM@2|Bacteria	502025.Hoch_2738|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5253693_10	1382359.JIAL01000001_gene1316	9.47e-70	271.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria,2JKNM@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8,UnbV_ASPIC,VCBS
CMS3_k127_5253693_15	398511.BpOF4_13400	2.367e-10	72.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_5253693_11	1267534.KB906757_gene1075	2.343e-52	205.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,3Y6YV@57723|Acidobacteria,2JKEW@204432|Acidobacteriia	204432|Acidobacteriia	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_2,TPR_8,UnbV_ASPIC,VCBS
CMS3_k127_5253693_2	452637.Oter_2944	2.696e-139	472.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS3_k127_5253693_6	335543.Sfum_1623	2.963e-120	412.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_5253693_13	344747.PM8797T_19041	1.71e-34	139.0	COG2346@1|root,COG2346@2|Bacteria,2J0RR@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS3_k127_5253693_9	452637.Oter_1502	8.03e-80	275.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,3K7BH@414999|Opitutae	2|Bacteria	V	PFAM ABC transporter related	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_5253693_14	483219.LILAB_31695	4.557e-32	145.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
CMS3_k127_5253693_12	313628.LNTAR_00100	3.807e-48	187.0	COG0564@1|root,COG0564@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluC	-	2.1.1.191,5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179,ko:K06180,ko:K06969	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2,S4
CMS3_k127_5253693_16	1267535.KB906767_gene4549	3.614e-06	60.0	COG3420@1|root,COG3420@2|Bacteria,3Y6PA@57723|Acidobacteria,2JMNE@204432|Acidobacteriia	204432|Acidobacteriia	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS3_k127_5253693_4	1125863.JAFN01000001_gene873	5.808e-124	409.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	conserved protein UCP016719	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS3_k127_5277554_6	391615.ABSJ01000002_gene467	0.0001425	47.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5277554_5	886293.Sinac_4659	9.992e-24	113.0	COG1520@1|root,COG1520@2|Bacteria,2IWVC@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_5277554_4	530564.Psta_0713	2.198e-28	125.0	COG3878@1|root,COG3878@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
CMS3_k127_5277554_2	237368.SCABRO_03138	3.824e-86	308.0	COG0168@1|root,COG0168@2|Bacteria,2IYFA@203682|Planctomycetes	203682|Planctomycetes	P	COG0168 Trk-type K transport systems, membrane components	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS3_k127_5277554_0	1123242.JH636437_gene6070	1.104e-170	561.0	COG2755@1|root,COG2755@2|Bacteria,2IYT9@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Lipase_GDSL_2
CMS3_k127_5277554_3	1403819.BATR01000090_gene2633	4.669e-67	255.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C,PA14
CMS3_k127_5277554_1	71139.XP_010046909.1	2.359e-88	304.0	COG4638@1|root,2QQJW@2759|Eukaryota,37M74@33090|Viridiplantae,3GARM@35493|Streptophyta	35493|Streptophyta	P	choline monooxygenase	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
CMS3_k127_5284876_0	314230.DSM3645_14945	1.21e-113	379.0	COG0673@1|root,COG0673@2|Bacteria,2IXUF@203682|Planctomycetes	2|Bacteria	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_528638_3	1278073.MYSTI_02730	2.345e-18	99.0	COG1073@1|root,COG1073@2|Bacteria,1MY4C@1224|Proteobacteria,42TB9@68525|delta/epsilon subdivisions,2WXEF@28221|Deltaproteobacteria,2YW3Y@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_528638_5	330214.NIDE4033	9.855e-10	60.0	COG1225@1|root,COG1225@2|Bacteria,3J12D@40117|Nitrospirae	40117|Nitrospirae	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_528638_4	1157490.EL26_03370	6.845e-17	88.0	COG1225@1|root,COG1225@2|Bacteria,1V6MU@1239|Firmicutes,4HK8J@91061|Bacilli,27A0F@186823|Alicyclobacillaceae	91061|Bacilli	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_528638_6	633147.Olsu_1365	3.081e-06	56.0	COG0695@1|root,COG0695@2|Bacteria,2H7ZC@201174|Actinobacteria,4CWIX@84998|Coriobacteriia	84998|Coriobacteriia	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3,Glutaredoxin
CMS3_k127_528638_1	483219.LILAB_20835	2.15e-158	516.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,43E81@68525|delta/epsilon subdivisions,2WZZ4@28221|Deltaproteobacteria,2YU4S@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_528638_2	998674.ATTE01000001_gene3954	2.946e-73	262.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS3_k127_528638_0	313612.L8106_24515	0.0	1163.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1H6Y0@1150|Oscillatoriales	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS3_k127_5310645_0	661478.OP10G_1583	4.294e-192	612.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS3_k127_5310645_13	663610.JQKO01000002_gene1298	1.167e-21	111.0	COG2931@1|root,COG3227@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,1QX6U@1224|Proteobacteria	1224|Proteobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Astacin,VCBS
CMS3_k127_5310645_15	65093.PCC7418_2098	5.838e-11	75.0	COG2755@1|root,COG2755@2|Bacteria,1G33R@1117|Cyanobacteria	1117|Cyanobacteria	E	GDSL-like lipase acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_5310645_10	557598.LHK_00843	4.001e-62	232.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,2KTZ4@206351|Neisseriales	206351|Neisseriales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_5310645_17	1144312.PMI09_05995	6.261e-07	63.0	COG0110@1|root,COG0110@2|Bacteria,1N3W2@1224|Proteobacteria,2VETH@28211|Alphaproteobacteria,4BAPI@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS3_k127_5310645_4	56110.Oscil6304_1709	2.556e-83	295.0	COG2244@1|root,COG2244@2|Bacteria,1G3GP@1117|Cyanobacteria,1HAX2@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS3_k127_5310645_1	1403819.BATR01000114_gene3892	4.264e-143	471.0	COG1053@1|root,COG1649@1|root,COG2755@1|root,COG4409@1|root,COG1053@2|Bacteria,COG1649@2|Bacteria,COG2755@2|Bacteria,COG4409@2|Bacteria,46UXH@74201|Verrucomicrobia,2ITNS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_5310645_12	1415779.JOMH01000001_gene2885	7.161e-25	115.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1X57M@135614|Xanthomonadales	135614|Xanthomonadales	E	Sodium alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS3_k127_5310645_7	404589.Anae109_4276	1.466e-68	251.0	COG3213@1|root,COG3213@2|Bacteria,1Q61U@1224|Proteobacteria,4328M@68525|delta/epsilon subdivisions,2WXFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NnrS protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
CMS3_k127_5310645_8	671143.DAMO_0255	1.025e-66	245.0	COG0438@1|root,COG3754@1|root,COG4372@1|root,COG5610@1|root,COG0438@2|Bacteria,COG3754@2|Bacteria,COG4372@2|Bacteria,COG5610@2|Bacteria,2NR6D@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	sll1424	-	2.1.1.80,3.1.1.61	ko:K01991,ko:K02557,ko:K07161,ko:K07484,ko:K13924,ko:K20444,ko:K21471	ko02020,ko02026,ko02030,ko02040,map02020,map02026,map02030,map02040	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01005,ko01011,ko02000,ko02022,ko02035	1.A.30.1,1.B.18,4.D.1.3	GT2,GT4	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,zf-IS66
CMS3_k127_5310645_3	1167006.UWK_01998	9.324e-90	310.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,42QJ7@68525|delta/epsilon subdivisions,2WPQE@28221|Deltaproteobacteria,2MKG7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_5310645_11	1300345.LF41_716	4.86e-61	217.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,1X6PT@135614|Xanthomonadales	135614|Xanthomonadales	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS3_k127_5310645_6	1049564.TevJSym_ab01230	1.445e-68	243.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_5310645_2	349521.HCH_01491	1.996e-117	387.0	COG1748@1|root,COG1748@2|Bacteria,1MY1G@1224|Proteobacteria,1RRUZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Dehydrogenase	lysDH	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS3_k127_5310645_16	84531.JMTZ01000014_gene2655	6.088e-10	73.0	COG3315@1|root,COG3315@2|Bacteria,1N2E7@1224|Proteobacteria	1224|Proteobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS3_k127_5310645_5	1123242.JH636438_gene5844	3.718e-69	248.0	COG1657@1|root,COG1657@2|Bacteria,2IXQ8@203682|Planctomycetes	203682|Planctomycetes	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_5310645_19	240016.ABIZ01000001_gene1049	0.000597	52.0	2BTK9@1|root,32NSZ@2|Bacteria,46X81@74201|Verrucomicrobia,2IUYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5310645_9	1121861.KB899942_gene3805	1.377e-65	233.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2JQ88@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_5326037_2	886293.Sinac_2224	6.681e-33	135.0	28H8P@1|root,2Z7KH@2|Bacteria,2IYE8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5326037_0	1089550.ATTH01000001_gene1884	1.322e-59	216.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_5326037_3	983920.Y88_1277	2.739e-19	102.0	COG2105@1|root,COG2105@2|Bacteria,1N814@1224|Proteobacteria,2UCQF@28211|Alphaproteobacteria,2KB1D@204457|Sphingomonadales	204457|Sphingomonadales	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS3_k127_5326037_1	1297742.A176_03990	2.331e-36	146.0	COG1670@1|root,COG1670@2|Bacteria,1RKT9@1224|Proteobacteria,42VCK@68525|delta/epsilon subdivisions,2WS7R@28221|Deltaproteobacteria,2Z14V@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	rimJ2	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS3_k127_5327649_1	251221.35214774	8.122e-95	343.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
CMS3_k127_5327649_0	765913.ThidrDRAFT_1807	8.979e-162	544.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,1RNRZ@1236|Gammaproteobacteria,1WWS7@135613|Chromatiales	135613|Chromatiales	K	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair	rapA	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
CMS3_k127_5327649_3	1158294.JOMI01000009_gene1103	1.54e-12	76.0	2CA0F@1|root,3420R@2|Bacteria,4P4FC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5327649_2	926562.Oweho_3368	2.452e-49	194.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBIN@246874|Cryomorphaceae	976|Bacteroidetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_5327649_4	502025.Hoch_3485	1.135e-10	74.0	COG3791@1|root,COG3791@2|Bacteria,1RD31@1224|Proteobacteria,43DVM@68525|delta/epsilon subdivisions,2WYZY@28221|Deltaproteobacteria,2Z0G7@29|Myxococcales	28221|Deltaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS3_k127_5327649_6	998674.ATTE01000001_gene2212	2.351e-05	56.0	COG2755@1|root,COG2755@2|Bacteria,1QZ4F@1224|Proteobacteria	1224|Proteobacteria	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_5327649_5	1158614.I592_01262	4.581e-07	62.0	COG1409@1|root,COG1409@2|Bacteria,1TT7M@1239|Firmicutes,4HBTM@91061|Bacilli,4B0TB@81852|Enterococcaceae	91061|Bacilli	S	Pfam:DUF303	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_5338644_1	114615.BRADO1150	3.171e-124	424.0	COG0467@1|root,COG1112@1|root,COG0467@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,2TSE1@28211|Alphaproteobacteria,3JSFJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Protein of unknown function (DUF4011)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,DUF3320,DUF4011,DUF559,WGR
CMS3_k127_5338644_2	1123276.KB893301_gene4312	2.843e-80	282.0	COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,47M78@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
CMS3_k127_5338644_4	886293.Sinac_5393	2.321e-06	61.0	COG1413@1|root,COG1413@2|Bacteria,2IXTT@203682|Planctomycetes	203682|Planctomycetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_5338644_0	1380394.JADL01000011_gene3969	2.978e-157	511.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,2JSPQ@204441|Rhodospirillales	204441|Rhodospirillales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS3_k127_5338644_3	313628.LNTAR_22654	7.543e-23	113.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
CMS3_k127_5359088_3	1192034.CAP_7258	5.177e-53	194.0	COG0745@1|root,COG0745@2|Bacteria,1PG0S@1224|Proteobacteria,4391F@68525|delta/epsilon subdivisions,2X46V@28221|Deltaproteobacteria,2YYDF@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5359088_1	344747.PM8797T_14594	1.556e-141	464.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_5359088_0	1123508.JH636452_gene7031	9.475e-189	595.0	COG4948@1|root,COG4948@2|Bacteria,2IY85@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.171	ko:K21624	ko00330,map00330	-	R11625	-	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS3_k127_5359088_2	1089550.ATTH01000001_gene296	2.208e-128	441.0	COG0733@1|root,COG0733@2|Bacteria,4P0HG@976|Bacteroidetes,1FJSG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
CMS3_k127_5387779_9	886293.Sinac_7312	1.68e-29	138.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
CMS3_k127_5387779_12	203119.Cthe_2148	1.859e-12	81.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,PG_binding_1
CMS3_k127_5387779_11	1292034.OR37_01079	1.612e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,1N413@1224|Proteobacteria,2U89X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5387779_13	795359.TOPB45_0257	5.641e-07	61.0	COG0265@1|root,COG0265@2|Bacteria,2GHRY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5387779_4	446470.Snas_4783	4.95e-67	235.0	COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria,4EZ6I@85014|Glycomycetales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_5387779_1	1297742.A176_05505	2.587e-89	315.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,430H1@68525|delta/epsilon subdivisions,2WVZX@28221|Deltaproteobacteria,2YUWZ@29|Myxococcales	28221|Deltaproteobacteria	L	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
CMS3_k127_5387779_0	1379698.RBG1_1C00001G0804	4.071e-116	401.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_5387779_8	278957.ABEA03000080_gene3199	3.406e-47	194.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K93U@414999|Opitutae	414999|Opitutae	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
CMS3_k127_5387779_7	794903.OPIT5_02660	3.566e-48	179.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K93U@414999|Opitutae	414999|Opitutae	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
CMS3_k127_5387779_2	411490.ANACAC_03496	3.001e-72	261.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_5387779_6	583355.Caka_1336	1.836e-52	201.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_5387779_5	583355.Caka_1335	1.782e-55	209.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS3_k127_5387779_3	402881.Plav_1564	1.482e-71	270.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,1JPZN@119043|Rhodobiaceae	28211|Alphaproteobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.27	ko:K01657,ko:K01665	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS3_k127_5387779_10	438753.AZC_1597	9.391e-23	113.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2U9QU@28211|Alphaproteobacteria,3EZSU@335928|Xanthobacteraceae	28211|Alphaproteobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_5401673_1	631362.Thi970DRAFT_03186	5.866e-37	146.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,1X0B5@135613|Chromatiales	135613|Chromatiales	M	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
CMS3_k127_5401673_0	765420.OSCT_0910	1.757e-55	211.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
CMS3_k127_5408837_1	1123242.JH636434_gene4399	2.243e-160	520.0	COG1413@1|root,COG1413@2|Bacteria,2IX4C@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_5408837_12	457429.ABJI02000794_gene6120	0.0004706	52.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
CMS3_k127_5408837_10	1057002.KB905370_gene3018	6.232e-24	119.0	COG3204@1|root,COG3204@2|Bacteria,1QVA9@1224|Proteobacteria	1224|Proteobacteria	L	pilus organization	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5408837_3	448385.sce4940	2.24e-109	386.0	COG1409@1|root,COG2133@1|root,COG5563@1|root,COG1409@2|Bacteria,COG2133@2|Bacteria,COG5563@2|Bacteria,1NS3S@1224|Proteobacteria,43AFC@68525|delta/epsilon subdivisions,2X64J@28221|Deltaproteobacteria,2Z0UN@29|Myxococcales	28221|Deltaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_5408837_8	344747.PM8797T_00177	2.8e-33	141.0	2ESRG@1|root,33K9V@2|Bacteria,2J33K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5408837_13	344747.PM8797T_07989	0.0009656	49.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS3_k127_5408837_4	1323663.AROI01000011_gene3218	1.403e-94	340.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_5408837_2	1382359.JIAL01000001_gene1858	1.788e-112	375.0	COG3424@1|root,COG3424@2|Bacteria,3Y37E@57723|Acidobacteria,2JHXK@204432|Acidobacteriia	204432|Acidobacteriia	Q	FAE1/Type III polyketide synthase-like protein	-	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
CMS3_k127_5408837_5	391626.OAN307_c45110	2.072e-76	267.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_5408837_14	298653.Franean1_0734	0.0009742	51.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria,4EVS9@85013|Frankiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS3_k127_5408837_9	1415779.JOMH01000001_gene1841	2.597e-31	142.0	COG0664@1|root,COG1033@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1X3P5@135614|Xanthomonadales	135614|Xanthomonadales	T	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	-	-	-	-	-	-	-	-	-	MMPL,cNMP_binding
CMS3_k127_5408837_7	1125863.JAFN01000001_gene422	3.566e-43	177.0	COG4191@1|root,COG4191@2|Bacteria,1R6WR@1224|Proteobacteria,42PFK@68525|delta/epsilon subdivisions,2WJSP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
CMS3_k127_5408837_0	234267.Acid_7369	5.268e-197	643.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_5408837_6	469617.FUAG_00725	2.515e-46	184.0	COG0242@1|root,COG0242@2|Bacteria,37BYH@32066|Fusobacteria	32066|Fusobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	-	-	-	-	-	-	-	-	-	-	Pep_deformylase
CMS3_k127_5408837_11	1128421.JAGA01000002_gene435	7.113e-11	74.0	COG2340@1|root,COG3103@1|root,COG2340@2|Bacteria,COG4991@2|Bacteria,2NQ03@2323|unclassified Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	CAP,Glyco_hydro_99,SH3_3,SH3_4
CMS3_k127_5415502_4	1396141.BATP01000004_gene5899	1.988e-63	232.0	COG1082@1|root,COG1082@2|Bacteria,46VAY@74201|Verrucomicrobia,2IVPH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS3_k127_5415502_7	298653.Franean1_4201	2.057e-05	55.0	COG0657@1|root,COG0657@2|Bacteria,2GPBH@201174|Actinobacteria,4EWBJ@85013|Frankiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS3_k127_5415502_5	1121921.KB898710_gene652	1.536e-50	192.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,1RZQU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the MtfA family	mtfA	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
CMS3_k127_5415502_0	880526.KE386488_gene893	8.606e-318	1024.0	COG0058@1|root,COG0297@1|root,COG0058@2|Bacteria,COG0297@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,22U9A@171550|Rikenellaceae	976|Bacteroidetes	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1,2.4.1.11,2.4.1.8	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R01555,R02111	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GH65,GT3,GT35	-	DUF3417,Glycogen_syn,Phosphorylase
CMS3_k127_5415502_1	641491.DND132_3086	3.95e-134	439.0	COG1449@1|root,COG1449@2|Bacteria,1R8JX@1224|Proteobacteria,42QA5@68525|delta/epsilon subdivisions,2WMM5@28221|Deltaproteobacteria,2M9GJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
CMS3_k127_5415502_3	563192.HMPREF0179_03199	6.994e-116	399.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2M9SK@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
CMS3_k127_5415502_2	1123508.JH636441_gene3371	1.501e-126	431.0	COG0448@1|root,COG0448@2|Bacteria,2IXP5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_5415502_6	1340493.JNIF01000003_gene3773	1.549e-43	164.0	COG3797@1|root,COG3797@2|Bacteria,3Y5RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS3_k127_5439371_4	1035308.AQYY01000002_gene594	6.491e-46	180.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_5439371_7	1121013.P873_11880	9.946e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,1RHI0@1224|Proteobacteria,1S454@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5439371_5	1449126.JQKL01000036_gene1950	1.226e-33	149.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
CMS3_k127_5439371_0	1122939.ATUD01000001_gene577	1.359e-161	549.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5439371_3	1038859.AXAU01000012_gene4246	3.911e-52	200.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2TTSG@28211|Alphaproteobacteria,3JRZP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS3_k127_5439371_1	1267535.KB906767_gene447	6.518e-126	448.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_5439371_8	323098.Nwi_3040	0.0004784	51.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria,2TWQ3@28211|Alphaproteobacteria,3JU8D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,dCache_1
CMS3_k127_5439371_2	351627.Csac_1279	4.54e-55	204.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,42GC7@68295|Thermoanaerobacterales	186801|Clostridia	D	Belongs to the ParA family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
CMS3_k127_5439371_6	1121024.AUCD01000001_gene1694	5.49e-10	65.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,27GJD@186828|Carnobacteriaceae	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_5464612_4	1296416.JACB01000004_gene1144	1.885e-07	63.0	29XW7@1|root,30JNK@2|Bacteria,4PHYF@976|Bacteroidetes,1IG8N@117743|Flavobacteriia,2YKMF@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5464612_1	575540.Isop_0278	2.066e-54	218.0	COG1073@1|root,COG1073@2|Bacteria,2IXK0@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS3_k127_5464612_2	1049564.TevJSym_ab00470	6.245e-44	183.0	2A6A4@1|root,30V2R@2|Bacteria,1RENE@1224|Proteobacteria,1SNHE@1236|Gammaproteobacteria,1JA5P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5464612_0	234267.Acid_3914	1.805e-118	407.0	COG2010@1|root,COG3386@1|root,COG2010@2|Bacteria,COG3386@2|Bacteria,3Y9A6@57723|Acidobacteria	2|Bacteria	C	PFAM SMP-30 Gluconolaconase	peaA	GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576	1.4.9.1	ko:K08685,ko:K14274	ko00040,ko00680,ko01120,map00040,map00680,map01120	-	R00606,R02427	RC00189,RC00713	ko00000,ko00001,ko01000	-	-	-	Cu2_monoox_C,Cu2_monooxygen,Dehyd-heme_bind,Qn_am_d_aII,Qn_am_d_aIII,Qn_am_d_aIV,SGL
CMS3_k127_5464612_3	1254432.SCE1572_22375	5.043e-43	181.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5479141_7	1244869.H261_04962	8.707e-63	229.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2JQ0D@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_5479141_10	1220583.GOACH_27_00480	7.829e-28	118.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4GAM7@85026|Gordoniaceae	201174|Actinobacteria	K	Regulates arginine biosynthesis genes	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
CMS3_k127_5479141_11	344747.PM8797T_17859	3.079e-27	121.0	COG0670@1|root,COG0670@2|Bacteria,2IZZS@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
CMS3_k127_5479141_4	945713.IALB_1905	3.573e-118	402.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_5479141_12	234267.Acid_6493	5.135e-20	106.0	COG4319@1|root,COG4319@2|Bacteria,3Y5BE@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
CMS3_k127_5479141_8	234267.Acid_5241	2.047e-61	222.0	COG1262@1|root,COG1262@2|Bacteria	234267.Acid_5241|-	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5479141_9	644968.DFW101_0852	2.06e-33	134.0	COG1611@1|root,COG1611@2|Bacteria,1RJ91@1224|Proteobacteria,42TR7@68525|delta/epsilon subdivisions,2WQUE@28221|Deltaproteobacteria,2MC13@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
CMS3_k127_5479141_6	1121346.KB899821_gene2709	3.412e-106	361.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,26TKU@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the FGGY kinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CMS3_k127_5479141_1	497964.CfE428DRAFT_0790	1.077e-149	492.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
CMS3_k127_5479141_3	314230.DSM3645_06454	6.41e-128	425.0	COG2211@1|root,COG2211@2|Bacteria,2IWTX@203682|Planctomycetes	203682|Planctomycetes	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
CMS3_k127_5479141_2	583355.Caka_2936	9.543e-142	458.0	COG1082@1|root,COG1082@2|Bacteria,46UVB@74201|Verrucomicrobia,3K7PN@414999|Opitutae	414999|Opitutae	G	AP endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS3_k127_5479141_0	1142394.PSMK_06840	1.071e-150	492.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_5479141_5	926549.KI421517_gene3363	7.671e-114	381.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
CMS3_k127_5479141_14	502025.Hoch_2692	2.321e-08	66.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,42Y39@68525|delta/epsilon subdivisions,2WSYZ@28221|Deltaproteobacteria,2YV2T@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS3_k127_5496258_1	502025.Hoch_2465	7.612e-102	335.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2YZ69@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS3_k127_5496258_2	1396418.BATQ01000088_gene1031	6.675e-54	208.0	COG2010@1|root,COG3241@1|root,COG2010@2|Bacteria,COG3241@2|Bacteria,46WAE@74201|Verrucomicrobia,2IVQW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrome_CBB3,PA14
CMS3_k127_5496258_0	1328313.DS2_17592	1.174e-119	406.0	COG2133@1|root,COG2133@2|Bacteria,1R5SW@1224|Proteobacteria,1S1CW@1236|Gammaproteobacteria,464YU@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5496258_4	478801.Ksed_00660	3.912e-11	70.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
CMS3_k127_5532963_5	575540.Isop_0897	7.609e-62	243.0	COG0515@1|root,COG0515@2|Bacteria,2IYFB@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_5532963_1	1254432.SCE1572_02460	9.463e-102	364.0	COG0515@1|root,COG2203@1|root,COG2204@1|root,COG2909@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2909@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Pkinase,Sigma54_activat,TPR_12
CMS3_k127_5532963_7	886293.Sinac_1412	3.039e-51	201.0	COG1355@1|root,COG1355@2|Bacteria,2IZEZ@203682|Planctomycetes	203682|Planctomycetes	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS3_k127_5532963_8	237368.SCABRO_03066	1.912e-44	176.0	COG0859@1|root,COG0859@2|Bacteria,2IXD5@203682|Planctomycetes	203682|Planctomycetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_5532963_0	1137799.GZ78_12510	7.071e-117	415.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,1RMNH@1236|Gammaproteobacteria,1XHAB@135619|Oceanospirillales	135619|Oceanospirillales	K	accessory protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CMS3_k127_5532963_10	1123242.JH636434_gene3967	7.685e-32	133.0	COG4112@1|root,COG4112@2|Bacteria,2IZBE@203682|Planctomycetes	203682|Planctomycetes	S	Phosphoesterase (MutT	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5532963_6	1267535.KB906767_gene4229	1.284e-51	199.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria,2JING@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
CMS3_k127_5532963_13	33876.JNXY01000006_gene932	2.098e-05	57.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria,4D9FS@85008|Micromonosporales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
CMS3_k127_5532963_3	661478.OP10G_2311	2.746e-67	253.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	nosF	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
CMS3_k127_5532963_12	661478.OP10G_2310	9.041e-09	68.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,DUF3526
CMS3_k127_5532963_2	1210884.HG799466_gene12492	2.302e-71	252.0	COG1131@1|root,COG1131@2|Bacteria,2IZ5V@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS3_k127_5532963_11	266117.Rxyl_0824	4.679e-24	115.0	COG3897@1|root,COG3897@2|Bacteria,2GTAU@201174|Actinobacteria,4CQPT@84995|Rubrobacteria	84995|Rubrobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
CMS3_k127_5532963_9	1267533.KB906733_gene2989	4.042e-43	182.0	COG0642@1|root,COG2205@2|Bacteria,3Y2M7@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_5532963_4	1121904.ARBP01000002_gene6976	2.079e-64	236.0	COG0745@1|root,COG0745@2|Bacteria,4NGXP@976|Bacteroidetes	976|Bacteroidetes	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_55801_5	479434.Sthe_0801	5.063e-75	265.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi,27XM2@189775|Thermomicrobia	189775|Thermomicrobia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS3_k127_55801_8	479434.Sthe_1809	2.331e-28	118.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi,27YGX@189775|Thermomicrobia	189775|Thermomicrobia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS3_k127_55801_7	344747.PM8797T_14244	7.387e-34	140.0	2DVZ6@1|root,32V0F@2|Bacteria,2J01K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_55801_6	545694.TREPR_0757	1.188e-49	204.0	COG1030@1|root,COG1030@2|Bacteria,2J57R@203691|Spirochaetes	203691|Spirochaetes	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
CMS3_k127_55801_10	177437.HRM2_17750	1.815e-16	95.0	COG1030@1|root,COG1030@2|Bacteria,1MY7A@1224|Proteobacteria,42SJX@68525|delta/epsilon subdivisions,2WPDE@28221|Deltaproteobacteria,2MK8F@213118|Desulfobacterales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS3_k127_55801_1	575540.Isop_2875	1.705e-119	395.0	COG4864@1|root,COG4864@2|Bacteria,2IXDK@203682|Planctomycetes	203682|Planctomycetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS3_k127_55801_0	1089548.KI783301_gene638	8.28e-146	471.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,3WFFB@539002|Bacillales incertae sedis	91061|Bacilli	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS3_k127_55801_2	1049564.TevJSym_aq00790	1.241e-117	385.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1J5GG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_0608	CoA_binding,Ligase_CoA
CMS3_k127_55801_4	575540.Isop_0271	1.294e-76	267.0	COG0142@1|root,COG0142@2|Bacteria,2IXUE@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS3_k127_55801_11	530564.Psta_4196	1.359e-13	82.0	2E533@1|root,3238B@2|Bacteria,2IZRS@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_55801_9	1480694.DC28_06585	2.843e-24	119.0	COG0755@1|root,COG1018@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1018@2|Bacteria,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	ccsA	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	Cytochrom_C_asm,Fer2,ResB
CMS3_k127_55801_3	1396141.BATP01000016_gene2844	8.002e-100	357.0	COG0755@1|root,COG0755@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS3_k127_5580302_0	1232410.KI421428_gene1119	3.8e-108	370.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43UDA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase S1 and S6, chymotrypsin Hap	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5595571_15	697282.Mettu_2963	9.452e-96	319.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,1XE5J@135618|Methylococcales	135618|Methylococcales	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
CMS3_k127_5595571_8	246197.MXAN_0958	5.6e-129	429.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,42PFX@68525|delta/epsilon subdivisions,2WJS3@28221|Deltaproteobacteria,2YXB6@29|Myxococcales	28221|Deltaproteobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
CMS3_k127_5595571_6	215803.DB30_5758	6.282e-144	503.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2YWNV@29|Myxococcales	28221|Deltaproteobacteria	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
CMS3_k127_5595571_2	1047013.AQSP01000101_gene609	1.126e-264	844.0	COG4447@1|root,COG4447@2|Bacteria,2NQN9@2323|unclassified Bacteria	2|Bacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
CMS3_k127_5595571_38	1123073.KB899242_gene1325	6.197e-06	57.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_2,Calx-beta,Laminin_G_3,PA14,VPEP
CMS3_k127_5595571_7	1379698.RBG1_1C00001G1403	1.047e-131	439.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
CMS3_k127_5595571_37	344747.PM8797T_09024	4.616e-06	61.0	COG2373@1|root,COG4219@1|root,COG2373@2|Bacteria,COG4219@2|Bacteria,2J096@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_M56
CMS3_k127_5595571_36	439235.Dalk_0743	2.767e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_5595571_12	42256.RradSPS_0864	2.509e-110	367.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_5595571_5	1313421.JHBV01000020_gene5292	3.013e-144	494.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,1IWCK@117747|Sphingobacteriia	976|Bacteroidetes	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_5595571_3	765420.OSCT_0993	2.144e-249	779.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi,3767V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K15052	ko00720,ko01200,map00720,map01200	M00376	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_5595571_35	1502850.FG91_01251	2.188e-06	56.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2K67Z@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5595571_27	269799.Gmet_0262	4.707e-34	139.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43UDD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
CMS3_k127_5595571_29	1142394.PSMK_18300	1.413e-26	126.0	COG3023@1|root,COG3023@2|Bacteria,2J4CI@203682|Planctomycetes	203682|Planctomycetes	MV	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS3_k127_5595571_26	1313172.YM304_41870	4.077e-36	145.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
CMS3_k127_5595571_21	1049564.TevJSym_af00460	5.438e-69	248.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,1J5DW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_5595571_18	439235.Dalk_0779	7.829e-81	295.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2MIVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
CMS3_k127_5595571_16	379066.GAU_1743	1.612e-93	323.0	COG0534@1|root,COG0534@2|Bacteria,1ZUAU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS3_k127_5595571_22	1348657.M622_00445	1.783e-66	238.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,2KU7S@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_5595571_28	444158.MmarC6_1371	3.24e-33	148.0	COG0840@1|root,arCOG02320@2157|Archaea,2Y7QV@28890|Euryarchaeota,23RVM@183939|Methanococci	183939|Methanococci	T	Integral membrane sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
CMS3_k127_5595571_31	314230.DSM3645_23261	3.483e-20	103.0	28I0W@1|root,30QX6@2|Bacteria,2IZI8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5595571_17	492774.JQMB01000003_gene2522	4.77e-86	304.0	COG4948@1|root,COG4948@2|Bacteria,1MV2S@1224|Proteobacteria,2TTFB@28211|Alphaproteobacteria,4BA6Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CMS3_k127_5595571_24	1173263.Syn7502_00392	1.674e-58	221.0	COG2071@1|root,COG2071@2|Bacteria,1G5CB@1117|Cyanobacteria,1H3HY@1129|Synechococcus	1117|Cyanobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS3_k127_5595571_39	452652.KSE_47880	4.476e-05	52.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,2M4X3@2063|Kitasatospora	201174|Actinobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5595571_9	1192034.CAP_7003	3.763e-123	406.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Cys Met metabolism	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS3_k127_5595571_11	1380394.JADL01000004_gene6049	1.284e-111	377.0	COG1167@1|root,COG1167@2|Bacteria,1MUJE@1224|Proteobacteria,2TQZZ@28211|Alphaproteobacteria,2JPG0@204441|Rhodospirillales	204441|Rhodospirillales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
CMS3_k127_5595571_32	1168289.AJKI01000046_gene887	4.433e-18	92.0	COG2836@1|root,COG2836@2|Bacteria,4NIC3@976|Bacteroidetes,2FZDZ@200643|Bacteroidia,3XK14@558415|Marinilabiliaceae	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS3_k127_5595571_33	1185652.USDA257_c28370	1.677e-09	72.0	COG2304@1|root,COG4249@1|root,COG2304@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TR94@28211|Alphaproteobacteria,4BM49@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_C,Peptidase_C14
CMS3_k127_5595571_10	391598.FBBAL38_09852	7.484e-121	421.0	COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia	976|Bacteroidetes	G	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
CMS3_k127_5595571_40	1298867.AUES01000004_gene595	0.0001411	45.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,3JR9U@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_5595571_20	1122176.KB903541_gene286	3.509e-78	293.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5595571_34	1250005.PHEL85_0319	1.141e-06	60.0	COG1404@1|root,COG1404@2|Bacteria,4PMB6@976|Bacteroidetes,1IJQ9@117743|Flavobacteriia,3VX5R@52959|Polaribacter	976|Bacteroidetes	O	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
CMS3_k127_5595571_25	85643.Tmz1t_1608	6.06e-41	160.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,2KXXM@206389|Rhodocyclales	206389|Rhodocyclales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS3_k127_5595571_0	518766.Rmar_2423	0.0	1272.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes	976|Bacteroidetes	T	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_5595571_13	1122137.AQXF01000004_gene1464	7.995e-99	346.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U2RG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_5595571_30	439235.Dalk_2217	4.801e-24	118.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MJFK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
CMS3_k127_5595571_41	1297742.A176_00134	0.0009926	52.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_5595571_1	1117647.M5M_10885	8.388e-268	841.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,1J5GX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	alsS	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS3_k127_5595571_4	1232683.ADIMK_1382	7.267e-243	756.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,464PE@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.71	ko:K00128,ko:K06447	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05049,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_5633203_0	330214.NIDE1937	0.0	1600.0	COG0209@1|root,COG0209@2|Bacteria,3J0MG@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
CMS3_k127_5633203_17	595460.RRSWK_06924	3.837e-19	95.0	2EHUP@1|root,33BKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5633203_4	316274.Haur_1017	8.363e-211	662.0	COG2224@1|root,COG2224@2|Bacteria,2G61J@200795|Chloroflexi,374VM@32061|Chloroflexia	32061|Chloroflexia	C	PFAM isocitrate lyase and phosphorylmutase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
CMS3_k127_5633203_3	1205680.CAKO01000035_gene319	7.534e-224	706.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria	1224|Proteobacteria	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	aceB	GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010	Malate_synthase
CMS3_k127_5633203_13	715451.ambt_03890	2.362e-23	117.0	COG5276@1|root,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria,46D9Z@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
CMS3_k127_5633203_18	867903.ThesuDRAFT_02119	2.677e-05	57.0	COG0202@1|root,COG0568@1|root,COG0202@2|Bacteria,COG0568@2|Bacteria	2|Bacteria	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6,2.7.7.7	ko:K02342,ko:K02909,ko:K03040,ko:K03046,ko:K03086	ko00230,ko00240,ko01100,ko03010,ko03020,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03010,map03020,map03030,map03430,map03440	M00178,M00183,M00260	R00375,R00376,R00377,R00378,R00435,R00441,R00442,R00443	RC02795	br01610,br01611,ko00000,ko00001,ko00002,ko01000,ko03011,ko03021,ko03032,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L,Sigma70_r4
CMS3_k127_5633203_5	575540.Isop_2730	3.996e-179	588.0	COG2719@1|root,COG2719@2|Bacteria,2IXSH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
CMS3_k127_5633203_6	1353529.M899_1925	1.351e-125	411.0	COG2718@1|root,COG2718@2|Bacteria,1MWQM@1224|Proteobacteria,42PDK@68525|delta/epsilon subdivisions,2MSPM@213481|Bdellovibrionales,2WJKJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
CMS3_k127_5633203_1	1128421.JAGA01000002_gene90	2.547e-298	929.0	COG2766@1|root,COG2766@2|Bacteria	2|Bacteria	T	protein kinase activity	prkA	GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
CMS3_k127_5633203_9	1382359.JIAL01000001_gene1834	1.291e-32	139.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_5633203_8	1382359.JIAL01000001_gene1834	6.602e-36	157.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_5633203_16	991905.SL003B_2714	1.597e-19	99.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TVZ2@28211|Alphaproteobacteria,4BQZC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Ndr family	pcaD	-	3.1.1.24,4.1.1.44	ko:K01055,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,CMD
CMS3_k127_5633203_12	1519439.JPJG01000104_gene1835	1.233e-23	110.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,2N772@216572|Oscillospiraceae	186801|Clostridia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5633203_15	658086.HMPREF0994_02638	4.189e-20	103.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,27J50@186928|unclassified Lachnospiraceae	186801|Clostridia	EJM	Nucleotidyl transferase	-	-	2.7.7.71,3.1.3.82,3.1.3.83	ko:K03273,ko:K15669	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771,R09772	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like,NTP_transferase,PNK3P
CMS3_k127_5633203_19	1137268.AZXF01000004_gene2278	6.235e-05	53.0	COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4EIZR@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_5633203_10	935863.AWZR01000004_gene432	5.718e-32	136.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1X691@135614|Xanthomonadales	135614|Xanthomonadales	S	competence protein	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS3_k127_5633203_7	1121930.AQXG01000001_gene1128	2.259e-99	344.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
CMS3_k127_5633203_14	498761.HM1_2405	9.964e-23	116.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS3_k127_5633203_2	243090.RB2663	1.034e-224	709.0	COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_5633203_11	1254432.SCE1572_22375	2.933e-31	143.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5650895_1	760192.Halhy_6175	1.911e-52	193.0	COG1525@1|root,COG1525@2|Bacteria,4P92I@976|Bacteroidetes	976|Bacteroidetes	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5650895_3	1379698.RBG1_1C00001G1111	4.608e-40	166.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,BBP2,Porin_2,Porin_4
CMS3_k127_5650895_4	235985.BBPN01000016_gene5864	4.322e-28	131.0	COG1032@1|root,COG1032@2|Bacteria,2I8XZ@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	-	-	-	ko:K18564	ko00332,ko01130,map00332,map01130	-	R10738	RC03266	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_5650895_2	269799.Gmet_2150	1.706e-44	172.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria,43UFV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_5650895_0	709797.CSIRO_3858	3.92e-68	250.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TU8Q@28211|Alphaproteobacteria,3K5YG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_5696189_0	886293.Sinac_7483	8.198e-99	336.0	COG0515@1|root,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_570727_0	1397528.Q671_03825	9.698e-168	540.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XNSE@135619|Oceanospirillales	135619|Oceanospirillales	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
CMS3_k127_570727_18	314230.DSM3645_23261	8.233e-40	162.0	28I0W@1|root,30QX6@2|Bacteria,2IZI8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_570727_4	1123242.JH636435_gene1547	9.464e-113	391.0	COG0457@1|root,COG0457@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_570727_26	1201293.AKXQ01000010_gene3278	1.839e-11	76.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria,1SK9K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
CMS3_k127_570727_13	619693.HMPREF6745_1302	2.656e-53	206.0	COG1233@1|root,COG1233@2|Bacteria,4NG5Y@976|Bacteroidetes,2FM9Y@200643|Bacteroidia	976|Bacteroidetes	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS3_k127_570727_3	421072.IO89_02190	1.967e-122	406.0	COG0304@1|root,COG0304@2|Bacteria,4NFBN@976|Bacteroidetes,1HXQ3@117743|Flavobacteriia,3HH6B@358033|Chryseobacterium	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_570727_25	1121918.ARWE01000001_gene3137	3.812e-12	74.0	COG0764@1|root,COG0764@2|Bacteria,1QZ5Z@1224|Proteobacteria,43CGT@68525|delta/epsilon subdivisions,2X7RZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_570727_2	1384054.N790_02195	4.716e-143	498.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,1RM9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG0840 Methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD,HD_5,Lactamase_B_2
CMS3_k127_570727_1	335543.Sfum_1695	7.504e-147	475.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2MQ3Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	PFAM Type II IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_570727_5	96561.Dole_3052	1.119e-109	369.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MHXJ@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_570727_33	387631.Asulf_01812	0.0004914	53.0	COG5635@1|root,arCOG02967@2157|Archaea	2157|Archaea	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_570727_17	485918.Cpin_1857	6.797e-40	168.0	COG4261@1|root,COG4261@2|Bacteria,4NF49@976|Bacteroidetes,1IT2S@117747|Sphingobacteriia	976|Bacteroidetes	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
CMS3_k127_570727_22	1232437.KL661961_gene3018	8.456e-19	100.0	COG2834@1|root,COG2834@2|Bacteria,1NDM6@1224|Proteobacteria,42VR3@68525|delta/epsilon subdivisions,2WRTR@28221|Deltaproteobacteria,2MM6C@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	-	-	-	-	-	-	-	-	-	LolA
CMS3_k127_570727_6	1313421.JHBV01000138_gene1215	1.531e-109	399.0	COG0204@1|root,COG2227@1|root,COG4258@1|root,COG0204@2|Bacteria,COG2227@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,1IQPB@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphate acyltransferases	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
CMS3_k127_570727_9	641143.HMPREF9331_02139	4.826e-76	285.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,1HY3M@117743|Flavobacteriia,1EQQ4@1016|Capnocytophaga	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
CMS3_k127_570727_27	292415.Tbd_1355	5.623e-09	70.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,VCBS
CMS3_k127_570727_34	1136417.AZWE01000010_gene2861	0.0009857	53.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DBHP@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase s1 and s6 chymotrypsin hap	sprI	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_570727_14	1284352.AOIG01000006_gene2882	7.448e-53	213.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,26RN9@186822|Paenibacillaceae	91061|Bacilli	V	Bacitracin ABC transporter ATP-binding protein	-	-	-	ko:K20459	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran,DUF4162
CMS3_k127_570727_30	519989.ECTPHS_14004	1.256e-07	55.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1WVZP@135613|Chromatiales	135613|Chromatiales	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
CMS3_k127_570727_19	886293.Sinac_7484	2.149e-39	158.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_570727_7	886293.Sinac_2761	8.571e-89	326.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_570727_21	1415779.JOMH01000001_gene2948	9.383e-24	119.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S6X1@1236|Gammaproteobacteria,1X450@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
CMS3_k127_570727_12	1146883.BLASA_1107	3.585e-55	202.0	COG0421@1|root,COG0421@2|Bacteria,2I2TN@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_570727_16	679935.Alfi_1538	3.662e-41	171.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,2FR15@200643|Bacteroidia	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
CMS3_k127_570727_28	1121931.AUHG01000012_gene2520	7.247e-08	66.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia	976|Bacteroidetes	IQ	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
CMS3_k127_570727_8	679935.Alfi_1540	5.295e-78	280.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,2FPUI@200643|Bacteroidia,22VRE@171550|Rikenellaceae	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_2,Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_570727_23	688246.Premu_2869	2.687e-17	93.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,2FTE9@200643|Bacteroidia	976|Bacteroidetes	IQ	acyl carrier protein	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_570727_32	338966.Ppro_0918	0.0004366	53.0	2CFZG@1|root,33KRJ@2|Bacteria,1NG58@1224|Proteobacteria,42WDR@68525|delta/epsilon subdivisions,2WS5I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-ketoacyl synthase, N-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ketoacyl-synt
CMS3_k127_570727_15	1249627.D779_0372	2.512e-48	188.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,1RMPP@1236|Gammaproteobacteria,1WXR7@135613|Chromatiales	135613|Chromatiales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_570727_20	679935.Alfi_1543	5.349e-25	117.0	COG0824@1|root,COG0824@2|Bacteria,4NRHH@976|Bacteroidetes,2FTJB@200643|Bacteroidia	976|Bacteroidetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_570727_29	1006004.GBAG_1411	1.201e-07	61.0	COG4706@1|root,COG4706@2|Bacteria,1N00A@1224|Proteobacteria,1S59J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	FabA
CMS3_k127_570727_24	1232437.KL661961_gene3015	1.773e-14	77.0	COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,42V4Y@68525|delta/epsilon subdivisions,2WRNP@28221|Deltaproteobacteria,2MMD1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS3_k127_570727_11	1232437.KL661961_gene3005	2.753e-70	248.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2MJ4H@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_570727_10	929713.NIASO_17950	6.38e-76	278.0	COG0457@1|root,COG0457@2|Bacteria,4PKJM@976|Bacteroidetes,1J0ZM@117747|Sphingobacteriia	976|Bacteroidetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS3_k127_5712007_1	91464.S7335_3937	1.457e-104	347.0	COG1117@1|root,COG1117@2|Bacteria,1G0P6@1117|Cyanobacteria,1GYK5@1129|Synechococcus	1117|Cyanobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS3_k127_5712007_3	338963.Pcar_0659	1.22e-48	192.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,43SH1@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PhoU domain	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS3_k127_5712007_0	314230.DSM3645_08352	3.688e-267	854.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2IWZA@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3,ABC_tran
CMS3_k127_5712007_2	314230.DSM3645_08347	9.118e-71	248.0	COG0845@1|root,COG0845@2|Bacteria,2IYMS@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_5736251_2	644282.Deba_3141	5.761e-08	66.0	COG1413@1|root,COG1413@2|Bacteria,1RK8P@1224|Proteobacteria,42VXW@68525|delta/epsilon subdivisions,2WRH4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_5736251_0	1210884.HG799462_gene7952	1.595e-313	989.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_5736251_1	1210884.HG799462_gene7951	2.288e-205	656.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_5743758_3	1144275.COCOR_02335	3.296e-61	222.0	COG4191@1|root,COG4191@2|Bacteria,1NV4N@1224|Proteobacteria,42ZK7@68525|delta/epsilon subdivisions,2WV0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_5743758_7	309807.SRU_2596	6.125e-36	146.0	COG0526@1|root,COG0526@2|Bacteria,4PF6F@976|Bacteroidetes,1FK7N@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5743758_1	1382304.JNIL01000001_gene646	2.464e-126	451.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,277XM@186823|Alicyclobacillaceae	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS3_k127_5743758_5	530564.Psta_2521	1.591e-53	194.0	COG1327@1|root,COG1327@2|Bacteria,2IZQ3@203682|Planctomycetes	203682|Planctomycetes	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS3_k127_5743758_6	751945.Theos_0943	7.61e-52	201.0	COG0486@1|root,COG0486@2|Bacteria,1WI11@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS3_k127_5743758_8	667014.Thein_0632	7.826e-35	154.0	COG0706@1|root,COG0706@2|Bacteria,2GHMX@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS3_k127_5743758_2	756272.Plabr_0624	5.661e-74	257.0	COG0639@1|root,COG0639@2|Bacteria,2IYH6@203682|Planctomycetes	203682|Planctomycetes	T	COG0639 Diadenosine tetraphosphatase and related	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_5743758_4	314230.DSM3645_04255	2.797e-60	220.0	COG0324@1|root,COG0324@2|Bacteria,2IYY6@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS3_k127_5743758_0	391625.PPSIR1_12878	1.49e-160	550.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2YYFS@29|Myxococcales	28221|Deltaproteobacteria	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS3_k127_5743758_9	926569.ANT_30070	8.169e-27	117.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS3_k127_5764980_0	479434.Sthe_1033	1.413e-164	535.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi,27XU6@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_5764980_1	1172181.KB911698_gene6050	1.766e-12	81.0	COG2936@1|root,COG2936@2|Bacteria,2I1ZG@201174|Actinobacteria	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
CMS3_k127_5767147_8	637905.SVI_0004	6.076e-37	163.0	COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,1RY2R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
CMS3_k127_5767147_5	1121939.L861_03010	2.773e-43	184.0	COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,1RY2R@1236|Gammaproteobacteria,1XN14@135619|Oceanospirillales	135619|Oceanospirillales	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	COX2,Cytochrom_C
CMS3_k127_5767147_7	247634.GPB2148_146	6.711e-38	166.0	COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,1RY2R@1236|Gammaproteobacteria,1JC12@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
CMS3_k127_5767147_15	1001585.MDS_2103	0.0009791	53.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,1RPYJ@1236|Gammaproteobacteria,1YDSH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	iJN746.PP_4253	Cytochrome_CBB3,FixP_N
CMS3_k127_5767147_6	1415779.JOMH01000001_gene566	2.064e-40	175.0	COG1622@1|root,COG2863@1|root,COG1622@2|Bacteria,COG2863@2|Bacteria,1MVYW@1224|Proteobacteria,1RY2R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
CMS3_k127_5767147_13	216595.PFLU_1891	1.795e-16	89.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria	1224|Proteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
CMS3_k127_5767147_1	404589.Anae109_2747	2.921e-94	349.0	COG0755@1|root,COG1333@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WPT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
CMS3_k127_5767147_11	1158338.JNLJ01000001_gene942	2.274e-23	114.0	COG0760@1|root,COG0760@2|Bacteria,2G5GE@200783|Aquificae	200783|Aquificae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
CMS3_k127_5767147_12	443144.GM21_3114	1.663e-17	94.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_5767147_10	1167006.UWK_00564	1.739e-25	123.0	2ENA5@1|root,33FXV@2|Bacteria,1P5GM@1224|Proteobacteria,432FV@68525|delta/epsilon subdivisions,2WX6T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5767147_4	204669.Acid345_0742	3.63e-44	175.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TPR_11
CMS3_k127_5767147_0	880073.Calab_1263	8.119e-176	578.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS3_k127_5767147_9	443143.GM18_1830	1.663e-33	149.0	COG4191@1|root,COG4191@2|Bacteria,1Q87X@1224|Proteobacteria,42Q2K@68525|delta/epsilon subdivisions,2WJTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_2
CMS3_k127_5767147_14	391587.KAOT1_14517	2.338e-08	67.0	2EBMU@1|root,335N1@2|Bacteria,4PPZS@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5767147_2	497964.CfE428DRAFT_1721	1.105e-88	313.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_5767147_3	1142394.PSMK_10450	2.339e-51	187.0	COG2081@1|root,COG2081@2|Bacteria,2IWW4@203682|Planctomycetes	203682|Planctomycetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS3_k127_5780607_9	1230457.C476_03743	2.556e-17	93.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5780607_7	68223.JNZY01000045_gene2209	5.94e-70	245.0	COG3384@1|root,COG3384@2|Bacteria,2GKTV@201174|Actinobacteria	201174|Actinobacteria	S	Extradiol ring-cleavage dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
CMS3_k127_5780607_3	1239962.C943_00092	9.82e-112	369.0	COG2878@1|root,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes	976|Bacteroidetes	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
CMS3_k127_5780607_0	1283300.ATXB01000001_gene1162	0.0	2365.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1XE3B@135618|Methylococcales	135618|Methylococcales	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_5780607_1	1283300.ATXB01000001_gene1163	1.096e-175	565.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1XESP@135618|Methylococcales	135618|Methylococcales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,RnfC_N,SLBB
CMS3_k127_5780607_2	1239962.C943_00086	9.294e-118	403.0	COG4658@1|root,COG4658@2|Bacteria,4NESE@976|Bacteroidetes,47XQE@768503|Cytophagia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS3_k127_5780607_8	1120953.AUBH01000002_gene1456	1.114e-50	201.0	COG4659@1|root,COG4659@2|Bacteria,1R6FE@1224|Proteobacteria,1RYZ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CMS3_k127_5780607_5	1239962.C943_00088	5.036e-87	292.0	COG4660@1|root,COG4660@2|Bacteria,4NHHP@976|Bacteroidetes	976|Bacteroidetes	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS3_k127_5780607_6	1250005.PHEL85_1699	2.768e-82	290.0	COG4657@1|root,COG4657@2|Bacteria,4PPXA@976|Bacteroidetes,1I9U6@117743|Flavobacteriia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS3_k127_5780607_4	1283300.ATXB01000001_gene1168	7.648e-107	353.0	COG0369@1|root,COG0369@2|Bacteria,1NCKQ@1224|Proteobacteria,1RR4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM Oxidoreductase FAD NAD(P)-binding	-	-	1.14.13.208,1.18.1.2,1.8.1.2	ko:K00380,ko:K02641,ko:K15511	ko00195,ko00362,ko00920,ko01100,ko01120,map00195,map00362,map00920,map01100,map01120	M00176	R00858,R09555	RC00065,RC01739	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	FAD_binding_6,Fer4,NAD_binding_1
CMS3_k127_5780607_10	1517416.IDAT_12000	3.273e-09	66.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,1RT11@1236|Gammaproteobacteria,2QFA7@267893|Idiomarinaceae	1236|Gammaproteobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Gmad1,PD40,Peptidase_S9,Peptidase_S9_N
CMS3_k127_5788787_1	1396141.BATP01000023_gene711	9.482e-64	228.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_5788787_0	1403819.BATR01000137_gene4830	8.137e-186	600.0	COG3119@1|root,COG3119@2|Bacteria,46UIK@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_5788787_2	1210884.HG799464_gene10860	2.675e-37	145.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K02022,ko:K21449	-	M00258	-	-	ko00000,ko00002,ko02000	1.B.40.2,3.A.1	-	-	FtsX,HlyD_3,MacB_PCD
CMS3_k127_5790998_18	1140.Synpcc7942_1288	1.753e-35	156.0	COG3831@1|root,COG3831@2|Bacteria,1GPKY@1117|Cyanobacteria,1H3GN@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF4240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4240
CMS3_k127_5790998_4	1122939.ATUD01000001_gene577	6.828e-109	390.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5790998_24	1201290.M902_3144	3.138e-09	70.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2MT9B@213481|Bdellovibrionales,2WT4M@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	cyclic nucleotide-binding	-	-	-	ko:K03321,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko02000,ko03000	2.A.53.3	-	-	FliG_C,cNMP_binding
CMS3_k127_5790998_8	504472.Slin_3688	3.09e-91	320.0	COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,47KW2@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_5790998_1	96561.Dole_1541	4.439e-139	456.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2MHKB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
CMS3_k127_5790998_13	1121935.AQXX01000127_gene1191	1.477e-69	269.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,1S91X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_5790998_3	696747.NIES39_C05180	3.42e-111	381.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
CMS3_k127_5790998_0	234267.Acid_6579	6.954e-145	500.0	COG3938@1|root,COG3938@2|Bacteria,3Y6TR@57723|Acidobacteria	57723|Acidobacteria	E	Proline racemase	-	-	5.1.1.4,5.1.1.8	ko:K01777,ko:K12658	ko00330,ko01100,map00330,map01100	-	R01255,R03296	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
CMS3_k127_5790998_9	459495.SPLC1_S371140	2.646e-88	309.0	COG0457@1|root,COG4225@1|root,COG0457@2|Bacteria,COG4225@2|Bacteria,1GIAH@1117|Cyanobacteria,1HFNG@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
CMS3_k127_5790998_10	864051.BurJ1DRAFT_3418	8.206e-86	297.0	28JCT@1|root,2Z97C@2|Bacteria,1R738@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5790998_12	1122179.KB890435_gene931	1.213e-71	269.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_5790998_6	760192.Halhy_3824	2.905e-106	380.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_5790998_5	1249627.D779_2280	1.071e-106	370.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
CMS3_k127_5790998_19	1144275.COCOR_06069	4.067e-33	136.0	COG2315@1|root,COG2315@2|Bacteria,1Q2G4@1224|Proteobacteria,4382J@68525|delta/epsilon subdivisions,2X3CK@28221|Deltaproteobacteria,2YVFB@29|Myxococcales	28221|Deltaproteobacteria	S	YjbR	difB	-	-	-	-	-	-	-	-	-	-	-	YjbR
CMS3_k127_5790998_2	1192034.CAP_4632	3.832e-136	439.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,42RTY@68525|delta/epsilon subdivisions,2WNFS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_5790998_15	861299.J421_6105	2.189e-66	247.0	COG0308@1|root,COG0739@1|root,COG0308@2|Bacteria,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K08642,ko:K21472	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Cu_amine_oxidN1,Peptidase_M1,Peptidase_M23
CMS3_k127_5790998_23	1043493.BBLU01000002_gene1861	1.901e-09	68.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS3_k127_5790998_21	477641.MODMU_2747	5.352e-13	78.0	COG1309@1|root,COG1309@2|Bacteria,2ISW3@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_5790998_14	379066.GAU_3599	2.061e-67	250.0	COG0596@1|root,COG0596@2|Bacteria,1ZUKC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5790998_26	1396418.BATQ01000049_gene403	1.696e-06	50.0	COG0607@1|root,COG0607@2|Bacteria,46W9V@74201|Verrucomicrobia,2IV0M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS3_k127_5790998_22	1185876.BN8_02686	3.27e-10	72.0	COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RW1@768503|Cytophagia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1,Rhodanese
CMS3_k127_5790998_11	391625.PPSIR1_25771	2.968e-84	291.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,42VTI@68525|delta/epsilon subdivisions,2WW2V@28221|Deltaproteobacteria,2YYXY@29|Myxococcales	28221|Deltaproteobacteria	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
CMS3_k127_5790998_7	113355.CM001775_gene3965	1.734e-103	349.0	COG1397@1|root,COG1397@2|Bacteria,1G30S@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS3_k127_5790998_25	575540.Isop_0069	5.068e-07	60.0	COG1595@1|root,COG1595@2|Bacteria,2J0K1@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
CMS3_k127_5790998_17	234267.Acid_7677	1.031e-38	157.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_5790998_16	530564.Psta_3450	8.77e-64	248.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_5790998_20	1131269.AQVV01000018_gene1908	7.348e-16	93.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_5797235_1	685778.AORL01000021_gene914	2.881e-82	298.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,2K8KF@204457|Sphingomonadales	204457|Sphingomonadales	O	Carbamoyltransferase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_5797235_2	1449049.JONW01000010_gene3522	5.515e-39	161.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_5797235_0	234267.Acid_4566	6.114e-103	358.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,TPR_16,TPR_4
CMS3_k127_5820441_5	502025.Hoch_1870	7.964e-114	377.0	COG3303@1|root,COG3303@2|Bacteria,1QXPE@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	cbcM	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_5820441_10	1265503.KB905160_gene2789	7.309e-42	175.0	COG2755@1|root,COG2755@2|Bacteria,1NM3C@1224|Proteobacteria,1SS88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS3_k127_5820441_3	344747.PM8797T_19597	1.244e-137	462.0	COG3119@1|root,COG3119@2|Bacteria,2IXIU@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS3_k127_5820441_13	1173026.Glo7428_4368	7.961e-31	139.0	COG1807@1|root,COG1807@2|Bacteria,1GR2A@1117|Cyanobacteria	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5820441_0	1047013.AQSP01000101_gene609	2.227e-238	760.0	COG4447@1|root,COG4447@2|Bacteria,2NQN9@2323|unclassified Bacteria	2|Bacteria	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_6,Sortilin-Vps10
CMS3_k127_5820441_1	234267.Acid_2720	6.017e-161	535.0	COG0624@1|root,COG0624@2|Bacteria,3Y2UM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_5820441_17	1303518.CCALI_02226	1.994e-27	130.0	COG2121@1|root,COG2121@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
CMS3_k127_5820441_11	574966.KB898656_gene1500	3.386e-38	147.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1XKPR@135619|Oceanospirillales	135619|Oceanospirillales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
CMS3_k127_5820441_18	309801.trd_0158	6.638e-27	114.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
CMS3_k127_5820441_8	309801.trd_0142	2.786e-82	285.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
CMS3_k127_5820441_19	309801.trd_0160	8.936e-18	87.0	COG0425@1|root,COG0425@2|Bacteria,2G7DF@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
CMS3_k127_5820441_20	319795.Dgeo_1519	6.22e-12	80.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5820441_15	1123009.AUID01000024_gene1455	1.325e-29	127.0	2E12M@1|root,32WIA@2|Bacteria,1VD2B@1239|Firmicutes,24NKB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5820441_12	1397528.Q671_02180	1.708e-34	145.0	COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RE50@1224|Proteobacteria,1S3P4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1
CMS3_k127_5820441_2	517418.Ctha_0124	2.676e-141	460.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_5820441_4	517418.Ctha_0126	4.383e-122	404.0	COG2516@1|root,COG2516@2|Bacteria	2|Bacteria	K	radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_5820441_6	517418.Ctha_0127	6.618e-103	362.0	COG1856@1|root,COG1856@2|Bacteria	2|Bacteria	S	radical SAM domain protein	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
CMS3_k127_5820441_9	517418.Ctha_0128	4.131e-78	281.0	COG0095@1|root,COG0095@2|Bacteria	2|Bacteria	H	Lipoate-protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,DUF116
CMS3_k127_5820441_14	517418.Ctha_0129	5.114e-30	124.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_5820441_22	1121324.CLIT_10c03340	0.0008255	49.0	COG2198@1|root,COG2198@2|Bacteria,1W0IV@1239|Firmicutes,24RH6@186801|Clostridia	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
CMS3_k127_5820441_21	644282.Deba_2868	8.015e-10	68.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_5820441_16	204669.Acid345_4315	1.443e-28	120.0	COG0251@1|root,COG0251@2|Bacteria,3Y57T@57723|Acidobacteria,2JJQ3@204432|Acidobacteriia	204432|Acidobacteriia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS3_k127_5820441_7	1380390.JIAT01000014_gene6241	4.068e-98	332.0	COG4948@1|root,COG4948@2|Bacteria,2I7AE@201174|Actinobacteria,4CPIJ@84995|Rubrobacteria	84995|Rubrobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5833527_8	246197.MXAN_4801	1.509e-06	54.0	COG3521@1|root,COG3521@2|Bacteria,1PEH5@1224|Proteobacteria,436QF@68525|delta/epsilon subdivisions,2WY4G@28221|Deltaproteobacteria,2YW11@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K11906	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS-SciN
CMS3_k127_5833527_6	330214.NIDE1969	2.413e-15	89.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria	2|Bacteria	T	FHA domain	impI	-	2.7.11.1	ko:K07169,ko:K08884,ko:K11894,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	3.A.23.1	-	-	FHA
CMS3_k127_5833527_12	1002339.HMPREF9373_2374	0.0007993	52.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,1S3GK@1236|Gammaproteobacteria,3NJ8C@468|Moraxellaceae	1236|Gammaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS3_k127_5833527_4	1265505.ATUG01000001_gene4575	4.674e-21	109.0	2CD96@1|root,32XZD@2|Bacteria,1N5W5@1224|Proteobacteria,42UZ9@68525|delta/epsilon subdivisions,2WR27@28221|Deltaproteobacteria,2MKNA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5833527_5	1267535.KB906767_gene4499	4.804e-20	96.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_5833527_2	1120963.KB894493_gene2908	1.444e-62	248.0	COG3516@1|root,COG3517@1|root,COG3516@2|Bacteria,COG3517@2|Bacteria,1MU5C@1224|Proteobacteria,1RNP7@1236|Gammaproteobacteria,2Q158@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	evpB	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
CMS3_k127_5833527_1	530564.Psta_1805	4.759e-90	315.0	COG0500@1|root,COG2835@1|root,COG2226@2|Bacteria,COG2835@2|Bacteria,2J1W2@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5833527_3	1410620.SHLA_16c000450	4.976e-48	175.0	COG4104@1|root,COG4104@2|Bacteria,1N2DB@1224|Proteobacteria	1224|Proteobacteria	S	PAAR motif	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
CMS3_k127_5833527_0	864051.BurJ1DRAFT_3712	4.23e-151	495.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2VSCS@28216|Betaproteobacteria,1KP2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	B12 binding domain	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS3_k127_5833527_7	457425.XNR_1866	4.728e-09	70.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GKQG@201174|Actinobacteria	201174|Actinobacteria	DT	Forkhead associated domain	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
CMS3_k127_5833527_10	762376.AXYL_00713	1.421e-05	58.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,3T2PW@506|Alcaligenaceae	28216|Betaproteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5833527_11	1522072.IL54_4265	2.09e-05	51.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K0PR@204457|Sphingomonadales	204457|Sphingomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS3_k127_5833527_9	1442599.JAAN01000035_gene737	1.11e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RNVA@1236|Gammaproteobacteria,1X6C3@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5,TPR_16,TPR_19
CMS3_k127_584699_2	1278073.MYSTI_01094	3.017e-174	556.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_584699_23	89187.ISM_00365	4.097e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,46R3Q@74030|Roseovarius	28211|Alphaproteobacteria	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	MA20_09680	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_584699_15	1499967.BAYZ01000041_gene2389	2.376e-26	124.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS3_k127_584699_10	1340493.JNIF01000004_gene849	1.627e-64	234.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria	57723|Acidobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS3_k127_584699_21	497964.CfE428DRAFT_1903	8.073e-12	74.0	COG1104@1|root,COG1104@2|Bacteria,46TNH@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_584699_20	697284.ERIC2_c07380	6.563e-15	85.0	COG0546@1|root,COG0546@2|Bacteria,1V6BF@1239|Firmicutes,4HHZW@91061|Bacilli,26SK8@186822|Paenibacillaceae	91061|Bacilli	S	haloacid dehalogenase	gph1	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS3_k127_584699_9	1461694.ATO9_22830	6.671e-68	241.0	COG0758@1|root,COG0758@2|Bacteria,1R5PU@1224|Proteobacteria,2TTZR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS3_k127_584699_22	1402135.SUH3_13065	9.385e-08	57.0	COG1040@1|root,COG1040@2|Bacteria,1NTIE@1224|Proteobacteria,2UNU2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584699_18	1402135.SUH3_13065	1.717e-18	89.0	COG1040@1|root,COG1040@2|Bacteria,1NTIE@1224|Proteobacteria,2UNU2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584699_19	1121946.AUAX01000002_gene199	3.563e-18	100.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4D8JS@85008|Micromonosporales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
CMS3_k127_584699_11	886293.Sinac_3627	3.811e-63	246.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_8,WD40
CMS3_k127_584699_4	449447.MAE_21180	3.947e-151	499.0	COG1834@1|root,COG1834@2|Bacteria,1G48J@1117|Cyanobacteria	1117|Cyanobacteria	E	amidinotransferase	-	-	2.1.4.1	ko:K00613	ko00260,ko00330,ko01100,map00260,map00330,map01100	M00047	R00565,R01989	RC00024,RC02749	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidinotransf
CMS3_k127_584699_26	1349822.NSB1T_07730	0.0006025	53.0	COG2246@1|root,COG2246@2|Bacteria,4NVF9@976|Bacteroidetes,2FUTU@200643|Bacteroidia,22YT7@171551|Porphyromonadaceae	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CMS3_k127_584699_17	224325.AF_0303	5.704e-20	106.0	arCOG07506@1|root,arCOG07506@2157|Archaea,2Y04Z@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584699_13	56110.Oscil6304_1374	3.114e-38	166.0	2DBHM@1|root,2Z9AY@2|Bacteria,1G396@1117|Cyanobacteria,1H9MI@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_584699_14	69014.TK1720	2.859e-30	134.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_584699_5	1242864.D187_001883	1.321e-113	393.0	COG0665@1|root,COG0665@2|Bacteria,1Q6SU@1224|Proteobacteria,42QKP@68525|delta/epsilon subdivisions	1224|Proteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.3	ko:K00273	ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146	-	R00366,R02457,R02894,R02923,R04221,R07400	RC00006,RC00018,RC00135	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_584699_7	1242864.D187_001882	5.158e-77	270.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2WJV8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K20534	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS3_k127_584699_6	324602.Caur_1631	4.747e-104	355.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_584699_8	1210884.HG799465_gene12185	8.231e-69	247.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS3_k127_584699_25	1463885.KL578422_gene3347	8.614e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,2IPYQ@201174|Actinobacteria	201174|Actinobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_584699_0	1123248.KB893370_gene5141	0.0	1371.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,1J0QI@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
CMS3_k127_584699_1	886293.Sinac_6971	2.114e-251	816.0	COG1082@1|root,COG2010@1|root,COG2133@1|root,COG3241@1|root,COG1082@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3241@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
CMS3_k127_584699_16	756272.Plabr_2090	1.834e-24	117.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
CMS3_k127_584699_12	272134.KB731324_gene3575	4.992e-45	177.0	COG3000@1|root,COG3000@2|Bacteria,1GAN0@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS3_k127_584699_3	1122939.ATUD01000001_gene577	2.021e-160	550.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_2	313624.NSP_13800	6.137e-144	485.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1G705@1117|Cyanobacteria,1HP47@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,RgpF
CMS3_k127_5900998_22	1499967.BAYZ01000014_gene6399	2.987e-23	116.0	COG0535@1|root,COG0535@2|Bacteria,2NR6I@2323|unclassified Bacteria	2|Bacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS3_k127_5900998_5	1291050.JAGE01000001_gene868	2.573e-134	451.0	COG1858@1|root,COG2730@1|root,COG3391@1|root,COG1858@2|Bacteria,COG2730@2|Bacteria,COG3391@2|Bacteria,1TSS4@1239|Firmicutes,24F1E@186801|Clostridia,3WHGQ@541000|Ruminococcaceae	186801|Clostridia	GP	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Dockerin_1,RicinB_lectin_2
CMS3_k127_5900998_0	880526.KE386488_gene1576	2.737e-248	795.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_9	880526.KE386488_gene1576	1.02e-94	346.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_10	880526.KE386488_gene1576	3.678e-88	325.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_17	1303518.CCALI_01012	1.094e-38	148.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
CMS3_k127_5900998_12	880526.KE386488_gene1576	7.52e-72	272.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_21	1137269.AZWL01000033_gene3311	8.424e-25	123.0	COG3408@1|root,COG3408@2|Bacteria,2H2QX@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS3_k127_5900998_18	583355.Caka_0965	5.288e-37	163.0	COG0823@1|root,COG1413@1|root,COG0823@2|Bacteria,COG1413@2|Bacteria,46XCP@74201|Verrucomicrobia,3K9X8@414999|Opitutae	414999|Opitutae	U	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_15	748247.AZKH_3771	5.313e-51	208.0	COG2227@1|root,COG2227@2|Bacteria,1R1PX@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_5900998_1	1280685.AUKC01000012_gene1489	1.522e-146	490.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1VPG9@1239|Firmicutes	1239|Firmicutes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS3_k127_5900998_6	521674.Plim_3151	5.06e-110	365.0	COG1657@1|root,COG3345@1|root,COG1657@2|Bacteria,COG3345@2|Bacteria,2IYVN@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_5900998_23	391625.PPSIR1_00907	7.636e-14	86.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5900998_26	1297742.A176_04476	5.7e-11	77.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_5900998_11	886293.Sinac_6489	2.443e-86	322.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_5900998_24	1210884.HG799466_gene12935	1.062e-12	77.0	COG1595@1|root,COG1595@2|Bacteria,2J35E@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_5900998_16	1278073.MYSTI_05750	6.878e-43	173.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1R60D@1224|Proteobacteria,42UZ2@68525|delta/epsilon subdivisions,2WR0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1,Glycos_transf_2
CMS3_k127_5900998_14	443143.GM18_2483	1.314e-53	201.0	COG1216@1|root,COG1216@2|Bacteria,1R60D@1224|Proteobacteria,42UZ2@68525|delta/epsilon subdivisions,2WR0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1,Glycos_transf_2
CMS3_k127_5900998_20	85643.Tmz1t_3252	1.214e-32	145.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,2WGU1@28216|Betaproteobacteria,2KZPH@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5900998_8	1380390.JIAT01000014_gene6208	2.617e-97	344.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,NB-ARC,Response_reg,TIR_2,TPR_10,TPR_12
CMS3_k127_5900998_3	1380394.JADL01000001_gene2784	2.181e-136	443.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria,2TVNH@28211|Alphaproteobacteria,2JQZB@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_5900998_13	290400.Jann_3673	1.396e-54	203.0	2DVSI@1|root,33WZN@2|Bacteria,1NK4P@1224|Proteobacteria,2UW3G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_4	290400.Jann_3672	2.793e-136	449.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS3_k127_5900998_19	926550.CLDAP_12690	2.528e-36	145.0	COG3059@1|root,COG3059@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
CMS3_k127_5900998_7	1157708.KB907474_gene1148	1.389e-103	359.0	COG3590@1|root,COG3590@2|Bacteria,1QQ5Q@1224|Proteobacteria,2VZP2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5900998_25	768671.ThimaDRAFT_3387	1.418e-12	78.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMFB@1236|Gammaproteobacteria,1X2JU@135613|Chromatiales	135613|Chromatiales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS3_k127_5914013_1	886293.Sinac_7494	2.397e-203	641.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_5914013_4	886293.Sinac_7498	3.652e-147	484.0	COG2010@1|root,COG2010@2|Bacteria,2IXZ4@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_5914013_5	886293.Sinac_7498	5.293e-121	397.0	COG2010@1|root,COG2010@2|Bacteria,2IXZ4@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_5914013_10	684949.ATTJ01000001_gene3005	7.79e-43	162.0	COG2318@1|root,COG2318@2|Bacteria,1WNBD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_5914013_13	994573.T472_0202455	1.473e-14	85.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia,36SCE@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS3_k127_5914013_14	861299.J421_3982	0.0004736	52.0	2BQKV@1|root,32JGY@2|Bacteria,1ZUYK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5914013_12	870187.Thini_0382	7.308e-20	96.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,463F1@72273|Thiotrichales	72273|Thiotrichales	L	PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
CMS3_k127_5914013_7	1123242.JH636434_gene5244	1.987e-76	281.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5914013_3	756272.Plabr_0662	5.194e-188	644.0	COG4102@1|root,COG4102@2|Bacteria,2J28W@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_5914013_0	756272.Plabr_0661	6.597e-280	890.0	COG2010@1|root,COG2010@2|Bacteria,2J1RW@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_5914013_8	443255.SCLAV_5205	3e-76	270.0	COG4447@1|root,COG4447@2|Bacteria,2GMJN@201174|Actinobacteria	201174|Actinobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
CMS3_k127_5914013_2	1002340.AFCF01000004_gene2990	1.267e-198	667.0	COG0574@1|root,COG0706@1|root,COG2897@1|root,COG0574@2|Bacteria,COG0706@2|Bacteria,COG2897@2|Bacteria,1Q33X@1224|Proteobacteria,2TV1E@28211|Alphaproteobacteria,34GC9@302485|Phaeobacter	28211|Alphaproteobacteria	GPU	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	60KD_IMP,PEP-utilizers,PPDK_N,Rhodanese
CMS3_k127_5914013_6	1198452.Jab_2c30820	1.756e-94	334.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,47913@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS3_k127_5914013_9	1049564.TevJSym_af00460	1.348e-66	246.0	COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,1RSFI@1236|Gammaproteobacteria,1J5DW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_5914013_11	1125863.JAFN01000001_gene2345	1.124e-26	123.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS3_k127_5923119_11	1297742.A176_05025	4.691e-59	221.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_5923119_16	561175.KB894096_gene647	3.826e-09	70.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5923119_15	886293.Sinac_7554	2.942e-30	126.0	COG1595@1|root,COG1595@2|Bacteria,2J386@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5923119_10	595460.RRSWK_02582	2.471e-63	248.0	COG4826@1|root,COG4826@2|Bacteria,2J2TV@203682|Planctomycetes	203682|Planctomycetes	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
CMS3_k127_5923119_8	314230.DSM3645_06659	3.447e-67	242.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
CMS3_k127_5923119_1	1121875.KB907547_gene2916	3.514e-233	745.0	COG1335@1|root,COG2453@1|root,COG1335@2|Bacteria,COG2453@2|Bacteria,4NXZM@976|Bacteroidetes	976|Bacteroidetes	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
CMS3_k127_5923119_5	334545.CCMG01000008_gene726	5.466e-134	437.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria,47FW5@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
CMS3_k127_5923119_20	1121875.KB907547_gene2916	5.627e-05	51.0	COG1335@1|root,COG2453@1|root,COG1335@2|Bacteria,COG2453@2|Bacteria,4NXZM@976|Bacteroidetes	976|Bacteroidetes	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
CMS3_k127_5923119_4	502025.Hoch_6690	1.277e-155	518.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WNAS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_5923119_9	398578.Daci_5445	2.132e-64	233.0	COG1073@1|root,COG1073@2|Bacteria,1RCY0@1224|Proteobacteria,2VR4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
CMS3_k127_5923119_13	1242864.D187_007675	2.672e-50	188.0	COG5285@1|root,COG5285@2|Bacteria,1R9W1@1224|Proteobacteria	1224|Proteobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS3_k127_5923119_2	391625.PPSIR1_32844	5.197e-192	632.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YUFS@29|Myxococcales	28221|Deltaproteobacteria	P	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS3_k127_5923119_14	44056.XP_009033965.1	1.082e-32	148.0	29QRV@1|root,2RX97@2759|Eukaryota	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	REJ,VCBS
CMS3_k127_5923119_6	1210884.HG799468_gene13605	4.533e-77	279.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
CMS3_k127_5923119_19	472759.Nhal_2104	5.069e-06	48.0	COG3339@1|root,COG3791@1|root,COG3339@2|Bacteria,COG3791@2|Bacteria,1MZR5@1224|Proteobacteria,1S912@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS3_k127_5923119_3	344747.PM8797T_27799	2.104e-180	578.0	COG3119@1|root,COG3119@2|Bacteria,2IXBF@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_5923119_18	1217656.F964_04520	2.105e-07	62.0	2EPHR@1|root,30ANQ@2|Bacteria,1RFDK@1224|Proteobacteria,1S507@1236|Gammaproteobacteria,3NJR8@468|Moraxellaceae	1236|Gammaproteobacteria	S	Putative general bacterial porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_7
CMS3_k127_5923119_7	1133849.O3I_021710	1.029e-67	258.0	COG0308@1|root,COG0308@2|Bacteria,2HJ8E@201174|Actinobacteria,4G5T5@85025|Nocardiaceae	201174|Actinobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5923119_12	234267.Acid_0985	1.366e-50	205.0	COG0652@1|root,COG0652@2|Bacteria,3Y7R6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_5923119_0	113395.AXAI01000053_gene2640	0.0	1052.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,3JQNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
CMS3_k127_5923119_17	234267.Acid_6265	1.918e-08	66.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_5943802_1	215803.DB30_6945	2.018e-135	460.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria,2YUQR@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_5943802_2	378806.STAUR_7389	2.076e-127	438.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria,2YUQR@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS3_k127_5943802_0	321327.CYA_2555	4.08e-238	758.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1GZ1F@1129|Synechococcus	1117|Cyanobacteria	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS3_k127_597683_1	240016.ABIZ01000001_gene2374	1.512e-122	421.0	COG2091@1|root,COG2091@2|Bacteria,46VE0@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS3_k127_597683_4	1521187.JPIM01000085_gene3414	2.475e-29	135.0	COG0545@1|root,COG0545@2|Bacteria,2GA7H@200795|Chloroflexi,3762K@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidylprolyl isomerase FKBP-type	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
CMS3_k127_597683_0	472759.Nhal_1400	4.377e-139	461.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,1X09A@135613|Chromatiales	135613|Chromatiales	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF,ThiS
CMS3_k127_597683_6	504728.K649_13920	2.124e-06	57.0	COG1310@1|root,COG1310@2|Bacteria,1WKMI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
CMS3_k127_597683_2	886293.Sinac_5597	3.074e-121	404.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2IZ4S@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108,4.2.1.59	ko:K02535,ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CMS3_k127_597683_3	247490.KSU1_B0556	9.555e-78	283.0	COG0673@1|root,COG0673@2|Bacteria,2IXAX@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_597683_5	247490.KSU1_C1551	8.657e-23	113.0	COG1376@1|root,COG1376@2|Bacteria,2J0C4@203682|Planctomycetes	203682|Planctomycetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
CMS3_k127_5987978_13	1173025.GEI7407_1075	3.288e-47	171.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1H6Y0@1150|Oscillatoriales	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS3_k127_5987978_7	880072.Desac_2826	2.331e-78	276.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,42U77@68525|delta/epsilon subdivisions,2WQ4R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS3_k127_5987978_4	1384054.N790_10515	2.46e-128	422.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,1RNF0@1236|Gammaproteobacteria,1X3SC@135614|Xanthomonadales	135614|Xanthomonadales	EGP	MFS transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5987978_18	1385935.N836_11085	4.183e-30	126.0	COG0454@1|root,COG0456@2|Bacteria,1G58K@1117|Cyanobacteria,1HGPV@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
CMS3_k127_5987978_10	1223521.BBJX01000001_gene1022	1.392e-59	213.0	COG4106@1|root,COG4106@2|Bacteria,1QZC8@1224|Proteobacteria,2WHJN@28216|Betaproteobacteria,4AJYU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS3_k127_5987978_8	313596.RB2501_06945	1.115e-65	237.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1HYHP@117743|Flavobacteriia	976|Bacteroidetes	S	Pyrroloquinoline quinone biosynthesis protein PqqB	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
CMS3_k127_5987978_17	289376.THEYE_A0183	2.936e-32	145.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,3J1FD@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS3_k127_5987978_14	349124.Hhal_0421	1.467e-46	186.0	COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,1T3FR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
CMS3_k127_5987978_0	1242864.D187_005767	7.577e-219	700.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CMS3_k127_5987978_3	429009.Adeg_0071	8.136e-129	424.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,42F68@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_5987978_15	1123368.AUIS01000004_gene237	5.606e-45	181.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,2NCX7@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS3_k127_5987978_26	644282.Deba_2090	8.511e-14	85.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM lipopolysaccharide heptosyltransferase I	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_5987978_20	1003200.AXXA_14333	9.312e-25	119.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,3T2PW@506|Alcaligenaceae	28216|Betaproteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_5987978_11	1286106.MPL1_00897	1.126e-57	225.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,462Q4@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_5987978_22	1166018.FAES_3313	2.003e-19	104.0	COG1409@1|root,COG1409@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia	976|Bacteroidetes	NU	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_5987978_23	404589.Anae109_3838	1.064e-18	99.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,43AFC@68525|delta/epsilon subdivisions,2X64J@28221|Deltaproteobacteria,2Z0UN@29|Myxococcales	28221|Deltaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS3_k127_5987978_16	1193181.BN10_520057	8.12e-41	174.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4FHZD@85021|Intrasporangiaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
CMS3_k127_5987978_5	237368.SCABRO_00241	1.168e-120	402.0	COG1260@1|root,COG1260@2|Bacteria,2IWUF@203682|Planctomycetes	203682|Planctomycetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
CMS3_k127_5987978_6	945713.IALB_1882	7.298e-112	373.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PA,PD40,PDZ_2,Peptidase_M28
CMS3_k127_5987978_25	635013.TherJR_0696	4.499e-15	87.0	COG3411@1|root,COG3411@2|Bacteria,1VCJG@1239|Firmicutes,24JC4@186801|Clostridia,265J0@186807|Peptococcaceae	186801|Clostridia	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx,DUF1636
CMS3_k127_5987978_12	266117.Rxyl_2275	1.783e-47	183.0	COG1028@1|root,COG1028@2|Bacteria,2H0SM@201174|Actinobacteria,4CT60@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5987978_28	1541065.JRFE01000024_gene1022	0.0008495	51.0	COG3016@1|root,COG3016@2|Bacteria,1G1JQ@1117|Cyanobacteria,3VI28@52604|Pleurocapsales	1117|Cyanobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
CMS3_k127_5987978_9	1296416.JACB01000044_gene4920	5.479e-63	246.0	COG1680@1|root,COG1680@2|Bacteria,4NIG6@976|Bacteroidetes,1I137@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_5987978_21	316278.SynRCC307_2369	2.616e-23	107.0	COG0216@1|root,COG0216@2|Bacteria	2|Bacteria	J	translation release factor activity	prfA	-	-	ko:K02835,ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS3_k127_5987978_24	521674.Plim_0306	2.109e-17	97.0	COG1657@1|root,COG1657@2|Bacteria,2IXVT@203682|Planctomycetes	203682|Planctomycetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	A2M_comp,DUF4159,Prenyltrans
CMS3_k127_5987978_1	886293.Sinac_6369	4.24e-163	569.0	COG0551@1|root,COG0551@2|Bacteria,2IXB2@203682|Planctomycetes	203682|Planctomycetes	L	Ca-dependent carbohydrate-binding module xylan-binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Cytochrome_CBB3,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
CMS3_k127_5987978_2	521674.Plim_0286	2.288e-130	430.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CMS3_k127_5987978_19	926566.Terro_1658	3.377e-28	120.0	COG1820@1|root,COG1820@2|Bacteria,3Y3NQ@57723|Acidobacteria,2JIST@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_5997738_36	595460.RRSWK_00820	3.29e-24	116.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5997738_39	1123514.KB905899_gene870	9.954e-13	79.0	29Y90@1|root,30K2S@2|Bacteria,1QE2C@1224|Proteobacteria,1TAEE@1236|Gammaproteobacteria,463G6@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_45	82654.Pse7367_2890	0.0005943	53.0	COG1073@1|root,COG1073@2|Bacteria,1G1YP@1117|Cyanobacteria,1H80J@1150|Oscillatoriales	1117|Cyanobacteria	S	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS3_k127_5997738_7	1112217.PPL19_16065	3.145e-142	494.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the DNA photolyase family	phrB	GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0018298,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS3_k127_5997738_9	344747.PM8797T_20643	4.153e-138	451.0	COG1520@1|root,COG1520@2|Bacteria,2IX2Z@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_5997738_27	1210884.HG799463_gene9989	7.762e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,2IZXS@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_5997738_33	1379270.AUXF01000001_gene2167	1.843e-27	123.0	28IQM@1|root,2Z8QA@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
CMS3_k127_5997738_24	1121033.AUCF01000027_gene2771	1.623e-57	213.0	COG5012@1|root,COG5012@2|Bacteria,1RJN6@1224|Proteobacteria,2U9SK@28211|Alphaproteobacteria,2JT2Z@204441|Rhodospirillales	204441|Rhodospirillales	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
CMS3_k127_5997738_19	331869.BAL199_17783	1.124e-74	274.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2TRF9@28211|Alphaproteobacteria,4BP85@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	Na+/Pi-cotransporter	MA20_30080	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
CMS3_k127_5997738_4	502025.Hoch_4458	1.328e-237	754.0	COG0517@1|root,COG2170@1|root,COG0517@2|Bacteria,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS3_k127_5997738_16	1279009.ADICEAN_03381	3.528e-79	278.0	COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,47PWT@768503|Cytophagia	976|Bacteroidetes	E	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	3.5.1.96	ko:K05526	ko00330,ko01100,map00330,map01100	-	R00411	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	AstE_AspA
CMS3_k127_5997738_38	1408437.JNJN01000041_gene155	2.464e-20	107.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,25XMY@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5997738_26	1192034.CAP_4484	6.013e-47	189.0	COG1621@1|root,COG1807@1|root,COG1621@2|Bacteria,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria,2YVRQ@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_3	387092.NIS_0272	5.17e-242	769.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2YMB2@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_5997738_40	1041159.AZUW01000010_gene3899	1.248e-11	69.0	COG1917@1|root,COG1917@2|Bacteria,1QU6U@1224|Proteobacteria,2TY5T@28211|Alphaproteobacteria,4B9VK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
CMS3_k127_5997738_29	756272.Plabr_2893	1.438e-35	154.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
CMS3_k127_5997738_20	756272.Plabr_1917	3.299e-74	271.0	COG3828@1|root,COG3828@2|Bacteria,2J1T0@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_5997738_32	314230.DSM3645_28712	8.335e-30	125.0	COG0720@1|root,COG0720@2|Bacteria,2IZMP@203682|Planctomycetes	203682|Planctomycetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS3_k127_5997738_5	391625.PPSIR1_31323	8.844e-217	688.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2YUS1@29|Myxococcales	28221|Deltaproteobacteria	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
CMS3_k127_5997738_14	521011.Mpal_0942	1.311e-96	333.0	COG1232@1|root,arCOG01522@2157|Archaea,2XY37@28890|Euryarchaeota	28890|Euryarchaeota	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS3_k127_5997738_37	1449355.JQNR01000005_gene5766	1.013e-22	113.0	COG0477@1|root,COG2814@2|Bacteria,2GMY5@201174|Actinobacteria	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
CMS3_k127_5997738_11	1121104.AQXH01000001_gene1906	3.169e-119	406.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1INRR@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS3_k127_5997738_18	1123257.AUFV01000003_gene829	1.345e-75	265.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1X3ZV@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS3_k127_5997738_43	1121271.AUCM01000010_gene2408	2.859e-06	58.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_5997738_13	1396141.BATP01000058_gene2029	1.024e-97	359.0	COG0515@1|root,COG0515@2|Bacteria,46UX7@74201|Verrucomicrobia,2IVEF@203494|Verrucomicrobiae	1396141.BATP01000058_gene2029|-	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_30	439235.Dalk_3476	5.04e-33	150.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42T39@68525|delta/epsilon subdivisions,2WPHT@28221|Deltaproteobacteria,2MPRZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_5997738_2	1499967.BAYZ01000001_gene5910	0.0	1377.0	COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECH74115_1262.ECH74115_5779,iECNA114_1301.ECNA114_4481,iECO26_1355.ECO26_5428,iECSP_1301.ECSP_5359,iECs_1301.ECs5235,iG2583_1286.G2583_5088,iJN746.PP_0977,iSBO_1134.SBO_4182,iSSON_1240.SSON_4443,iYL1228.KPN_04663,iZ_1308.Z5870	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS3_k127_5997738_28	247490.KSU1_C0304	5.85e-38	163.0	COG1039@1|root,COG1039@2|Bacteria,2IZ83@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_44	658187.LDG_8838	5.674e-05	51.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,1JCI2@118969|Legionellales	118969|Legionellales	K	Transcriptional regulatory protein, C terminal	lrpR	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_5997738_25	323259.Mhun_3025	4.359e-49	185.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,2N98Y@224756|Methanomicrobia	224756|Methanomicrobia	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
CMS3_k127_5997738_34	1144307.PMI04_01422	3.919e-27	116.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,2K5VW@204457|Sphingomonadales	204457|Sphingomonadales	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS3_k127_5997738_42	313612.L8106_23660	1.18e-07	65.0	COG3014@1|root,COG3014@2|Bacteria,1GR3H@1117|Cyanobacteria,1HI7D@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_35	247490.KSU1_C1680	1.794e-25	122.0	COG0764@1|root,COG0764@2|Bacteria,2IZNA@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS3_k127_5997738_15	886293.Sinac_7507	6.793e-85	297.0	COG5267@1|root,COG5267@2|Bacteria,2IYR3@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS3_k127_5997738_21	886293.Sinac_6720	7.051e-74	265.0	COG4102@1|root,COG4102@2|Bacteria,2IXUC@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_5997738_17	1123242.JH636435_gene1534	5.591e-77	284.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_0	1123242.JH636435_gene2121	0.0	1589.0	28KJF@1|root,2Z84W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_41	342113.DM82_5178	3.222e-08	65.0	COG3209@1|root,COG3209@2|Bacteria,1R5DQ@1224|Proteobacteria,2VMRN@28216|Betaproteobacteria,1K430@119060|Burkholderiaceae	28216|Betaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5997738_8	1396141.BATP01000006_gene5432	2.031e-139	481.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
CMS3_k127_5997738_10	1288963.ADIS_1259	9.795e-133	466.0	COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_5997738_6	1047013.AQSP01000089_gene1174	1.527e-156	513.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT
CMS3_k127_5997738_22	314230.DSM3645_05180	7.472e-73	269.0	COG2159@1|root,COG2159@2|Bacteria,2IYMW@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS3_k127_5997738_31	1267533.KB906733_gene2855	5.159e-31	141.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS3_k127_5997738_12	886293.Sinac_1580	1.521e-105	383.0	COG3356@1|root,COG3356@2|Bacteria,2IX5S@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS3_k127_5997738_1	344747.PM8797T_15676	0.0	1416.0	COG0726@1|root,COG1413@1|root,COG2133@1|root,COG3474@1|root,COG0726@2|Bacteria,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,2IXJQ@203682|Planctomycetes	203682|Planctomycetes	C	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2,VCBS
CMS3_k127_5997738_23	323261.Noc_1510	3.311e-63	227.0	COG0500@1|root,COG2226@2|Bacteria,1RC3Q@1224|Proteobacteria,1S76S@1236|Gammaproteobacteria,1WYJ4@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_6044624_0	1201293.AKXQ01000016_gene3529	2.267e-156	542.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,1RZK1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_6044624_1	309807.SRU_2448	8.016e-140	458.0	COG1228@1|root,COG1228@2|Bacteria,4P0JM@976|Bacteroidetes	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_6044624_3	1906.SFRA_30675	1.854e-08	61.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria	201174|Actinobacteria	M	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	DUF1080,ThuA
CMS3_k127_6044624_2	227377.CBU_0433	5.23e-23	107.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1JE6A@118969|Legionellales	118969|Legionellales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS3_k127_6048266_3	243090.RB6961	4.944e-07	52.0	COG1595@1|root,COG1595@2|Bacteria,2J0IJ@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6048266_0	314230.DSM3645_08387	7.24e-198	632.0	COG3119@1|root,COG3119@2|Bacteria,2IXUN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_6048266_2	986075.CathTA2_1653	1.067e-51	199.0	COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli	91061|Bacilli	P	membrane	yrkO	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CMS3_k127_6048266_1	324602.Caur_0649	3.751e-97	347.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_6066963_18	1463909.KL585962_gene4720	2.717e-14	86.0	2B90Y@1|root,322BP@2|Bacteria,2HYKS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6066963_14	1192034.CAP_1503	1.051e-31	138.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,434YV@68525|delta/epsilon subdivisions,2WZ9S@28221|Deltaproteobacteria,2Z1NI@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6066963_22	379066.GAU_1004	7.363e-07	61.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	cpaE	-	2.7.13.3	ko:K02282,ko:K02482,ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022,ko02035,ko02044,ko03000,ko03036,ko03400	-	-	-	HATPase_c,HTH_18,HTH_8,HisKA,Response_reg
CMS3_k127_6066963_3	870187.Thini_4450	9.448e-104	362.0	COG3220@1|root,COG3220@2|Bacteria,1R9AA@1224|Proteobacteria,1S3KZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
CMS3_k127_6066963_8	1298593.TOL_1468	5.886e-55	194.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1XKEA@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
CMS3_k127_6066963_17	1122132.AQYH01000010_gene4009	5.662e-15	86.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_6066963_2	484770.UFO1_3275	6.145e-105	361.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4H2A2@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_6066963_16	906888.JCM19314_1604	1.907e-16	88.0	COG2020@1|root,COG2020@2|Bacteria,4NTAC@976|Bacteroidetes,1I4A9@117743|Flavobacteriia	976|Bacteroidetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS3_k127_6066963_0	595536.ADVE02000001_gene753	3.538e-158	518.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,36ZVX@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS3_k127_6066963_15	118173.KB235914_gene1427	8.908e-29	119.0	COG2442@1|root,COG2442@2|Bacteria,1G7SB@1117|Cyanobacteria,1HCGW@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CMS3_k127_6066963_12	1469607.KK073768_gene593	2.951e-37	143.0	COG4634@1|root,COG4634@2|Bacteria,1G6P5@1117|Cyanobacteria,1HNV5@1161|Nostocales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6066963_24	378806.STAUR_4755	4.473e-06	60.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria,2YYWS@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6066963_7	518766.Rmar_1702	7.644e-58	213.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1FIU8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CMS3_k127_6066963_19	521674.Plim_1137	1.244e-12	77.0	2E3B2@1|root,32YAK@2|Bacteria,2J19J@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
CMS3_k127_6066963_11	1122939.ATUD01000012_gene3173	2.009e-41	160.0	2ASH4@1|root,31HXG@2|Bacteria,2HMFJ@201174|Actinobacteria,4CQBD@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_6066963_9	649638.Trad_1462	1.048e-42	175.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS3_k127_6066963_10	1123278.KB893387_gene4395	1.434e-41	167.0	COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,47M5Z@768503|Cytophagia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS3_k127_6066963_21	675813.VIB_001805	4.015e-10	66.0	COG0599@1|root,COG0599@2|Bacteria,1PYYS@1224|Proteobacteria,1RU74@1236|Gammaproteobacteria,1Y1NN@135623|Vibrionales	135623|Vibrionales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6066963_4	452637.Oter_3546	1.089e-101	346.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS3_k127_6066963_1	1121011.AUCB01000057_gene3932	2.713e-139	452.0	COG4409@1|root,COG4409@2|Bacteria,4PEZ3@976|Bacteroidetes,1IFJC@117743|Flavobacteriia,23I9E@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS3_k127_6066963_5	1396418.BATQ01000043_gene6410	1.155e-66	258.0	COG2755@1|root,COG2755@2|Bacteria,46V3A@74201|Verrucomicrobia,2IVQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_6066963_6	1267534.KB906754_gene2777	3.391e-66	238.0	COG0337@1|root,COG0337@2|Bacteria,3Y2T4@57723|Acidobacteria,2JI0C@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS3_k127_6066963_20	1396141.BATP01000047_gene3964	7.519e-11	67.0	COG1063@1|root,COG1063@2|Bacteria,46USX@74201|Verrucomicrobia,2IWQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_6066963_13	414684.RC1_2768	3.837e-34	145.0	COG2981@1|root,COG2981@2|Bacteria,1MWAA@1224|Proteobacteria,2TT6E@28211|Alphaproteobacteria,2JSUF@204441|Rhodospirillales	204441|Rhodospirillales	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
CMS3_k127_6096991_1	886293.Sinac_0381	4.812e-203	644.0	COG4102@1|root,COG4102@2|Bacteria,2IX0F@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6096991_0	886293.Sinac_0382	1.375e-208	673.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CMS3_k127_611235_0	573370.DMR_44650	2.47e-226	726.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2M832@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS3_k127_611235_33	313612.L8106_07274	1.04e-06	62.0	COG0823@1|root,COG0823@2|Bacteria,1GBDE@1117|Cyanobacteria	1117|Cyanobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_611235_27	583355.Caka_1800	3.425e-38	153.0	COG2042@1|root,COG2042@2|Bacteria	2|Bacteria	S	rRNA processing	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	DTW,Ribo_biogen_C
CMS3_k127_611235_23	247490.KSU1_C0795	2.822e-44	175.0	COG0859@1|root,COG0859@2|Bacteria,2IYZS@203682|Planctomycetes	203682|Planctomycetes	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02841,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_611235_34	767434.Fraau_1379	2.621e-06	59.0	COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,1X40C@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
CMS3_k127_611235_22	1122179.KB890434_gene874	1.715e-45	183.0	COG4733@1|root,COG5276@1|root,COG4733@2|Bacteria,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_611235_26	1068978.AMETH_0058	6.321e-40	172.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_611235_7	1192034.CAP_4202	2.804e-127	420.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,42UZV@68525|delta/epsilon subdivisions,2X5RT@28221|Deltaproteobacteria,2YUED@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CMS3_k127_611235_10	661478.OP10G_3177	2.945e-110	375.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
CMS3_k127_611235_4	314230.DSM3645_15865	2.526e-172	559.0	COG3119@1|root,COG3119@2|Bacteria,2IYB8@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_611235_31	543526.Htur_3524	4.807e-19	102.0	arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,23UZV@183963|Halobacteria	183963|Halobacteria	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_611235_9	667014.Thein_1737	4.606e-111	367.0	COG0382@1|root,COG0382@2|Bacteria,2GI94@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS3_k127_611235_25	1267535.KB906767_gene4499	1.851e-41	159.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria,2JJS7@204432|Acidobacteriia	204432|Acidobacteriia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS3_k127_611235_12	1267533.KB906733_gene3472	7.459e-106	379.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
CMS3_k127_611235_1	1396418.BATQ01000132_gene3984	4.388e-217	715.0	COG1413@1|root,COG1621@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG1621@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46UEG@74201|Verrucomicrobia,2ITUX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
CMS3_k127_611235_30	575540.Isop_2930	1.645e-26	117.0	COG3258@1|root,COG3258@2|Bacteria,2J1GU@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
CMS3_k127_611235_35	391625.PPSIR1_20349	5.35e-05	57.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_611235_32	1254432.SCE1572_36405	3.662e-09	60.0	COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,42P15@68525|delta/epsilon subdivisions,2WK8D@28221|Deltaproteobacteria,2YZAE@29|Myxococcales	28221|Deltaproteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,rve
CMS3_k127_611235_20	1121481.AUAS01000006_gene877	1.54e-46	189.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
CMS3_k127_611235_6	886293.Sinac_2761	1.29e-143	501.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_611235_24	886293.Sinac_7484	4.951e-44	185.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_611235_13	1033732.CAHI01000015_gene513	4.566e-104	353.0	COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,22U7U@171550|Rikenellaceae	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	NQRA,NQRA_SLBB
CMS3_k127_611235_8	1453500.AT05_07560	2.071e-121	403.0	COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,1HXYV@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
CMS3_k127_611235_28	391598.FBBAL38_07470	4.069e-38	154.0	COG2869@1|root,COG2869@2|Bacteria,4NF7A@976|Bacteroidetes,1HZG0@117743|Flavobacteriia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
CMS3_k127_611235_16	926562.Oweho_3404	3.209e-76	273.0	COG1347@1|root,COG1347@2|Bacteria,4NGD9@976|Bacteroidetes,1HXGP@117743|Flavobacteriia,2PBGM@246874|Cryomorphaceae	976|Bacteroidetes	C	Rnf-Nqr subunit, membrane protein	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS3_k127_611235_15	1237149.C900_02249	2.896e-81	276.0	COG2209@1|root,COG2209@2|Bacteria,4NEU0@976|Bacteroidetes,47KRI@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	-	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS3_k127_611235_3	1124780.ANNU01000051_gene2071	2.177e-178	567.0	COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,47NPF@768503|Cytophagia	976|Bacteroidetes	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS3_k127_611235_18	675815.VOA_002618	5.185e-63	229.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1XSQ4@135623|Vibrionales	135623|Vibrionales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS3_k127_611235_11	1207063.P24_15751	1.948e-106	365.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TR1V@28211|Alphaproteobacteria,2JQZQ@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1905 NADH ubiquinone oxidoreductase 24 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS3_k127_611235_14	1031288.AXAA01000016_gene987	2.38e-87	301.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,36UKJ@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.10,1.17.1.11,1.17.1.9	ko:K00123,ko:K05299,ko:K22341	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_611235_5	555088.DealDRAFT_1821	2.592e-154	504.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,42JP3@68298|Syntrophomonadaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS3_k127_611235_2	452637.Oter_0373	7.354e-193	612.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA3	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS3_k127_611235_19	1210884.HG799464_gene10548	6.675e-53	208.0	COG3568@1|root,COG3568@2|Bacteria,2IXGB@203682|Planctomycetes	203682|Planctomycetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_611235_17	404589.Anae109_2716	2.627e-72	252.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales	28221|Deltaproteobacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
CMS3_k127_611235_21	237368.SCABRO_03057	7.172e-46	184.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CMS3_k127_611235_29	945713.IALB_1713	2.622e-36	149.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS3_k127_6124935_0	575540.Isop_2326	1.997e-85	317.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_6124935_1	1232437.KL662020_gene700	3.331e-50	203.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS3_k127_6125405_2	378806.STAUR_5515	6.178e-34	142.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,43823@68525|delta/epsilon subdivisions,2X3C5@28221|Deltaproteobacteria,2YVD0@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS3_k127_6125405_1	349521.HCH_06984	2.815e-87	296.0	COG0363@1|root,COG0363@2|Bacteria,1MVEA@1224|Proteobacteria,1RQ2V@1236|Gammaproteobacteria,1XIYW@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
CMS3_k127_6125405_0	313628.LNTAR_06724	5.564e-196	618.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_6133254_5	67267.JNXT01000092_gene5502	1.703e-21	109.0	COG2304@1|root,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
CMS3_k127_6133254_1	1229204.AMYY01000011_gene155	1.216e-119	426.0	COG2304@1|root,COG2304@2|Bacteria,1N4IM@1224|Proteobacteria,2U389@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS3_k127_6133254_2	1229204.AMYY01000011_gene157	2.24e-76	266.0	COG1721@1|root,COG1721@2|Bacteria,1PR6Q@1224|Proteobacteria,2V9IZ@28211|Alphaproteobacteria,4BT3F@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_6133254_0	1515746.HR45_00355	8.181e-126	412.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RN5G@1236|Gammaproteobacteria,2Q901@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_6133254_6	1198114.AciX9_2836	5.198e-08	64.0	COG0457@1|root,COG0457@2|Bacteria	1198114.AciX9_2836|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6159629_3	886293.Sinac_3636	5.649e-228	736.0	COG0236@1|root,COG0764@1|root,COG1028@1|root,COG3266@1|root,COG3321@1|root,COG0236@2|Bacteria,COG0764@2|Bacteria,COG1028@2|Bacteria,COG3266@2|Bacteria,COG3321@2|Bacteria,2IY7E@203682|Planctomycetes	203682|Planctomycetes	IQ	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_6159629_0	886293.Sinac_3637	0.0	2265.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2IYQE@203682|Planctomycetes	203682|Planctomycetes	IQ	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
CMS3_k127_6159629_5	1499967.BAYZ01000105_gene3484	5.88e-120	425.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	fabH1	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
CMS3_k127_6159629_8	886293.Sinac_3640	1.141e-113	392.0	COG0596@1|root,COG0596@2|Bacteria,2IYDE@203682|Planctomycetes	203682|Planctomycetes	S	Serine aminopeptidase, S33	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
CMS3_k127_6159629_4	398767.Glov_2271	2.476e-171	569.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,43S9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3	ko:K01897,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	iAF987.Gmet_2229	AMP-binding,AMP-binding_C
CMS3_k127_6159629_7	338966.Ppro_3118	2.204e-115	383.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,42NGH@68525|delta/epsilon subdivisions,2WKS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-Beta hydroxysteroid dehydrogenase isomerase	-	-	1.1.1.394,1.1.1.412	ko:K21271,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
CMS3_k127_6159629_19	391625.PPSIR1_19799	8.971e-34	141.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	2.7.8.7	ko:K00997,ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS3_k127_6159629_23	1122602.ATXP01000012_gene1729	2.845e-23	102.0	COG4327@1|root,COG4327@2|Bacteria,2IRIC@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
CMS3_k127_6159629_1	517418.Ctha_1886	3.338e-240	757.0	COG4147@1|root,COG4147@2|Bacteria,1FDIY@1090|Chlorobi	1090|Chlorobi	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS3_k127_6159629_28	344747.PM8797T_04720	3.008e-12	78.0	2ENVX@1|root,33GGY@2|Bacteria,2J3VH@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6159629_21	290397.Adeh_0163	5.838e-26	124.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	CP_0175	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45,SprT-like
CMS3_k127_6159629_16	1089550.ATTH01000001_gene910	9.776e-42	173.0	COG3540@1|root,COG3540@2|Bacteria,4NDUS@976|Bacteroidetes,1FJNA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	COG3540 Phosphodiesterase alkaline phosphatase D	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
CMS3_k127_6159629_30	426117.M446_2235	2.495e-07	64.0	COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2U677@28211|Alphaproteobacteria,1JRJ3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6159629_2	1121904.ARBP01000032_gene2005	4.274e-229	761.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
CMS3_k127_6159629_15	926566.Terro_2908	3.519e-52	206.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,3Y6YV@57723|Acidobacteria,2JKEW@204432|Acidobacteriia	204432|Acidobacteriia	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,TPR_11,TPR_2,TPR_8,UnbV_ASPIC,VCBS
CMS3_k127_6159629_24	1267535.KB906767_gene5368	7.044e-23	105.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene5368|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6159629_22	1123242.JH636435_gene2796	3.39e-24	113.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_6159629_9	1121904.ARBP01000013_gene454	5.36e-105	364.0	COG3540@1|root,COG3540@2|Bacteria,4NDUS@976|Bacteroidetes,47NKM@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
CMS3_k127_6159629_14	420324.KI911943_gene5343	3.731e-55	205.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS3_k127_6159629_29	1121015.N789_03880	4.162e-11	69.0	COG2050@1|root,COG2050@2|Bacteria,1RF3N@1224|Proteobacteria,1S82J@1236|Gammaproteobacteria,1XCYH@135614|Xanthomonadales	135614|Xanthomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_6159629_20	105559.Nwat_1249	1.803e-28	128.0	COG4123@1|root,COG4123@2|Bacteria,1N6QK@1224|Proteobacteria,1SKXT@1236|Gammaproteobacteria,1X0IT@135613|Chromatiales	135613|Chromatiales	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_6159629_27	1382230.ASAP_1256	1.509e-12	80.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria,2JTCN@204441|Rhodospirillales	204441|Rhodospirillales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS3_k127_6159629_25	215803.DB30_3709	6.407e-18	91.0	COG3832@1|root,COG3832@2|Bacteria,1PQB7@1224|Proteobacteria,43E0W@68525|delta/epsilon subdivisions,2WZDG@28221|Deltaproteobacteria,2Z1WA@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS3_k127_6159629_32	1101190.ARWB01000001_gene2107	5.942e-05	55.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2TV76@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	General secretion pathway protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CMS3_k127_6159629_26	1469245.JFBG01000027_gene1448	2.875e-17	94.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	type II secretion system	pilC	-	-	ko:K02653,ko:K12278	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_6159629_11	1442599.JAAN01000026_gene1258	1.295e-75	273.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1X36S@135614|Xanthomonadales	135614|Xanthomonadales	NU	General secretion pathway protein	xcsE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS3_k127_6159629_33	1386089.N865_18910	0.0003727	51.0	2EHZA@1|root,33BQS@2|Bacteria,2IJZ0@201174|Actinobacteria,4FGP6@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6159629_31	1297742.A176_00134	7.118e-06	59.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6159629_17	1121481.AUAS01000006_gene877	1.586e-35	155.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
CMS3_k127_6159629_10	1121937.AUHJ01000013_gene869	5.267e-80	285.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,4645R@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II)	epmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
CMS3_k127_6159629_12	530564.Psta_2401	2.404e-67	235.0	COG0231@1|root,COG0231@2|Bacteria,2IZ4X@203682|Planctomycetes	203682|Planctomycetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS3_k127_6159629_6	1123242.JH636435_gene1881	5.075e-119	393.0	COG1509@1|root,COG1509@2|Bacteria,2IYGS@203682|Planctomycetes	203682|Planctomycetes	C	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS3_k127_6159629_18	234267.Acid_0555	4.045e-34	143.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
CMS3_k127_6159629_13	630626.EBL_c14480	1.18e-63	246.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	rfbB	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran
CMS3_k127_6175088_15	556269.ACDQ01000002_gene1123	2.506e-52	190.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,4723Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS3_k127_6175088_28	1463853.JOHW01000008_gene881	1.863e-06	61.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GKQH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
CMS3_k127_6175088_13	1185876.BN8_00782	5.509e-55	209.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6175088_12	886293.Sinac_7507	3.968e-58	225.0	COG5267@1|root,COG5267@2|Bacteria,2IYR3@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS3_k127_6175088_14	1123377.AUIV01000005_gene1702	7.87e-55	201.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,1RMSQ@1236|Gammaproteobacteria,1X37Y@135614|Xanthomonadales	135614|Xanthomonadales	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS3_k127_6175088_17	1123508.JH636439_gene756	6.974e-40	165.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2IWVF@203682|Planctomycetes	203682|Planctomycetes	T	FHA domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF_2,SpoIIE
CMS3_k127_6175088_27	1246995.AFR_19245	1.243e-07	62.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS3_k127_6175088_2	521674.Plim_0408	1.72e-176	569.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_6175088_6	1142394.PSMK_15850	3.744e-115	381.0	COG2805@1|root,COG2805@2|Bacteria,2IXRP@203682|Planctomycetes	203682|Planctomycetes	NU	COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_6175088_3	886293.Sinac_6460	1.309e-159	531.0	COG2804@1|root,COG2804@2|Bacteria,2IXSA@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_6175088_20	530564.Psta_2772	3.125e-19	99.0	2CNIE@1|root,32SH6@2|Bacteria,2J02V@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6175088_29	1210884.HG799464_gene10789	4.374e-06	58.0	2E7HG@1|root,331ZY@2|Bacteria,2J0MZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6175088_25	522306.CAP2UW1_3069	6.841e-08	62.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,2VU1J@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_6175088_18	1206744.BAGL01000002_gene4279	1.625e-38	162.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FU85@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS3_k127_6175088_26	886293.Sinac_3817	8.838e-08	66.0	COG1716@1|root,COG1716@2|Bacteria,2IZA4@203682|Planctomycetes	203682|Planctomycetes	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS3_k127_6175088_24	58123.JOFJ01000012_gene5336	2.75e-08	67.0	COG2199@1|root,COG3706@2|Bacteria,2IBIC@201174|Actinobacteria,4EH95@85012|Streptosporangiales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS3_k127_6175088_9	373903.Hore_12350	1.021e-75	261.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WAD4@53433|Halanaerobiales	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS3_k127_6175088_19	575540.Isop_3168	2.969e-32	133.0	COG0103@1|root,COG0103@2|Bacteria,2J01J@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS3_k127_6175088_16	639282.DEFDS_0249	1.004e-40	158.0	COG0102@1|root,COG0102@2|Bacteria,2GFHA@200930|Deferribacteres	200930|Deferribacteres	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS3_k127_6175088_7	443143.GM18_3258	7.073e-113	382.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43TCB@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAF987.Gmet_0122	Fer4_9,PK,PK_C
CMS3_k127_6175088_30	335659.S23_47990	6.372e-06	58.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2TU29@28211|Alphaproteobacteria,3JQN5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	HEAT repeat	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS3_k127_6175088_4	1232410.KI421421_gene3600	7.112e-147	487.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS3_k127_6175088_10	671143.DAMO_1644	6.796e-75	279.0	COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria	2|Bacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
CMS3_k127_6175088_0	1123371.ATXH01000003_gene1895	4.743e-262	840.0	COG0653@1|root,COG0653@2|Bacteria,2GGR1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS3_k127_6175088_21	710111.FraQA3DRAFT_4235	2.852e-17	92.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4ERW3@85013|Frankiales	201174|Actinobacteria	T	response regulator	tcrX	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_6175088_8	671143.DAMO_2146	2.184e-88	304.0	COG0167@1|root,COG0167@2|Bacteria,2NNVA@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2,1.3.98.1	ko:K00226,ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01867,R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15540	DHO_dh
CMS3_k127_6175088_23	756272.Plabr_1789	1.475e-14	86.0	COG0597@1|root,COG0597@2|Bacteria,2J0RI@203682|Planctomycetes	203682|Planctomycetes	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS3_k127_6175088_22	886293.Sinac_6088	1.141e-15	82.0	COG1734@1|root,COG1734@2|Bacteria,2J04D@203682|Planctomycetes	203682|Planctomycetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS3_k127_6175088_11	883067.HMPREF9237_01149	3.18e-68	243.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4D3G2@85005|Actinomycetales	201174|Actinobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerD	GO:0008150,GO:0040007	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS3_k127_6175088_5	338963.Pcar_0553	7.551e-133	471.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,43S4V@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	GIY-YIG type nucleases (URI domain)	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS3_k127_6175088_1	398767.Glov_3444	9.737e-252	798.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,43U9W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS3_k127_6182789_2	1047013.AQSP01000142_gene242	2.993e-125	426.0	COG2511@1|root,COG2511@2|Bacteria	2|Bacteria	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
CMS3_k127_6182789_1	1123508.JH636445_gene6683	7.842e-159	518.0	COG4102@1|root,COG4102@2|Bacteria,2IY0X@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6182789_0	497964.CfE428DRAFT_1927	3.775e-185	602.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,HlyD_3,PSCyt1,PSCyt2,PSD1,RNA_pol_Rpb1_5
CMS3_k127_6212539_7	247490.KSU1_C1555	2.589e-06	59.0	COG1432@1|root,COG1432@2|Bacteria,2J2NW@203682|Planctomycetes	203682|Planctomycetes	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
CMS3_k127_6212539_8	1223523.H340_11595	0.0006493	51.0	COG5126@1|root,COG5126@2|Bacteria	2|Bacteria	DTZ	Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5,EF-hand_7
CMS3_k127_6212539_0	215803.DB30_2605	2.913e-103	377.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria,2YTXM@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19,TPR_8,Transglut_core
CMS3_k127_6212539_6	448385.sce7186	5.479e-26	127.0	COG0457@1|root,COG0457@2|Bacteria,1Q2H1@1224|Proteobacteria,4383J@68525|delta/epsilon subdivisions,2X3DM@28221|Deltaproteobacteria,2YVKC@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19
CMS3_k127_6212539_2	886293.Sinac_2872	4.499e-89	318.0	COG1446@1|root,COG1446@2|Bacteria,2IZ4V@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2,DUF4440
CMS3_k127_6212539_1	269799.Gmet_2684	2.366e-101	339.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria,43TNU@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
CMS3_k127_6212539_3	404589.Anae109_1378	2.74e-75	270.0	COG0585@1|root,COG0585@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS3_k127_6212539_5	429009.Adeg_1604	2.834e-32	145.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_6212539_4	1396141.BATP01000003_gene5164	2.292e-63	241.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia,2IV14@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6361746_3	1123508.JH636449_gene7339	3.777e-16	85.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
CMS3_k127_6361746_4	1297865.APJD01000003_gene6054	4.395e-10	69.0	COG1309@1|root,COG1309@2|Bacteria,1NFRC@1224|Proteobacteria,2UGXZ@28211|Alphaproteobacteria,3K199@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6361746_1	1230476.C207_04405	8.916e-68	259.0	COG1680@1|root,COG1680@2|Bacteria,1PDR2@1224|Proteobacteria,2U487@28211|Alphaproteobacteria,3JXAT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_6361746_2	530564.Psta_1021	4.174e-29	126.0	2EEU3@1|root,338MM@2|Bacteria,2J3PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6361746_0	1121405.dsmv_0232	1.821e-108	368.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43BS9@68525|delta/epsilon subdivisions,2X733@28221|Deltaproteobacteria,2MPJG@213118|Desulfobacterales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS3_k127_638091_0	1192034.CAP_8976	8.308e-67	254.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YWWP@29|Myxococcales	28221|Deltaproteobacteria	KLT	COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,Pkinase_Tyr,WD40
CMS3_k127_638091_1	1210884.HG799466_gene12935	4.924e-07	60.0	COG1595@1|root,COG1595@2|Bacteria,2J35E@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
CMS3_k127_6397122_9	1469613.JT55_18180	1.303e-12	79.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	prtI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6397122_3	1254432.SCE1572_07365	8.608e-80	271.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2Z0H3@29|Myxococcales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS3_k127_6397122_0	102129.Lepto7375DRAFT_7659	5.2e-108	375.0	COG0006@1|root,COG0006@2|Bacteria,1G0UJ@1117|Cyanobacteria,1H9NX@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS3_k127_6397122_7	391625.PPSIR1_12803	6.376e-22	113.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6397122_1	768671.ThimaDRAFT_3204	4.014e-98	334.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,1SH3R@1236|Gammaproteobacteria,1X2K7@135613|Chromatiales	135613|Chromatiales	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6397122_2	768671.ThimaDRAFT_3205	2.769e-89	319.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS3_k127_6397122_5	84531.JMTZ01000018_gene3876	3.243e-30	138.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1X4F0@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS3_k127_6397122_4	1207063.P24_14539	3.049e-59	218.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,2JPBX@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_6397122_10	10160.XP_004631700.1	1.038e-11	79.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,4955J@7742|Vertebrata,3JDQS@40674|Mammalia,35GS3@314146|Euarchontoglires,4Q4AP@9989|Rodentia	33208|Metazoa	W	hyaluronan metabolic process	ITIH3	GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0008150,GO:0009892,GO:0009987,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034774,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097708,GO:0098772,GO:0099503	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA
CMS3_k127_6397122_11	530564.Psta_1625	7.224e-11	75.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02674,ko:K07114	-	-	-	-	ko00000,ko02000,ko02035,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	CHU_C,Lipase_GDSL_2,Neisseria_PilC,VWA,VWA_2,VWA_3
CMS3_k127_6397122_6	443144.GM21_1102	1.29e-28	133.0	COG4585@1|root,COG4585@2|Bacteria,1QXNA@1224|Proteobacteria,43C4A@68525|delta/epsilon subdivisions,2WPFP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS3_k127_6397122_8	509190.Cseg_0417	4.878e-19	97.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6404415_0	1144275.COCOR_03421	7.182e-113	404.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
CMS3_k127_6425653_0	1117108.PAALTS15_07974	1.845e-50	182.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC6I@91061|Bacilli,26TJS@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_6425653_1	1343739.PAP_03820	1.046e-05	56.0	COG0460@1|root,arCOG01351@2157|Archaea,2XSWF@28890|Euryarchaeota,242SK@183968|Thermococci	183968|Thermococci	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
CMS3_k127_6478954_4	1267535.KB906767_gene4238	2.926e-10	72.0	COG0329@1|root,COG0329@2|Bacteria,3Y6I2@57723|Acidobacteria,2JMAW@204432|Acidobacteriia	204432|Acidobacteriia	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6478954_1	935845.JADQ01000007_gene1686	1.143e-108	362.0	COG0451@1|root,COG0451@2|Bacteria,1TPHV@1239|Firmicutes,4HCJR@91061|Bacilli,26SNR@186822|Paenibacillaceae	91061|Bacilli	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_6478954_2	497964.CfE428DRAFT_6006	8.434e-99	342.0	COG0673@1|root,COG0673@2|Bacteria,46TKX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_6478954_5	1210884.HG799466_gene12507	3.346e-07	61.0	COG1595@1|root,COG1595@2|Bacteria,2J3T4@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
CMS3_k127_6478954_3	309801.trd_A0786	2.453e-43	183.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,27YUJ@189775|Thermomicrobia	189775|Thermomicrobia	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_6478954_0	886293.Sinac_6968	1.609e-181	586.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CMS3_k127_6512160_2	1227739.Hsw_1264	5.434e-12	70.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
CMS3_k127_6512160_1	448385.sce6209	9.473e-59	209.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,42RGX@68525|delta/epsilon subdivisions,2WNKJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152,ko:K05520,ko:K05687	ko05012,map05012	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	DJ-1_PfpI
CMS3_k127_6512160_3	1123376.AUIU01000013_gene1810	2.823e-11	68.0	COG1135@1|root,COG1135@2|Bacteria,3J0VT@40117|Nitrospirae	40117|Nitrospirae	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
CMS3_k127_6512160_0	1101191.KI912577_gene896	7.846e-172	559.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,1JS8T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_6515610_4	59894.ENSFALP00000004519	1.447e-15	91.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,483KS@7711|Chordata,48WWG@7742|Vertebrata,4GQX0@8782|Aves	33208|Metazoa	S	Transmembrane and TPR repeat-containing protein 4	TMTC4	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_6515610_1	1122939.ATUD01000001_gene577	8.307e-87	321.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6515610_3	1123242.JH636435_gene2776	3.526e-34	136.0	COG3682@1|root,COG3682@2|Bacteria,2J0N4@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_6515610_2	886293.Sinac_1394	9.43e-53	216.0	COG4219@1|root,COG4219@2|Bacteria,2IZRJ@203682|Planctomycetes	203682|Planctomycetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS3_k127_6515610_0	926569.ANT_16550	2.315e-131	428.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_6515610_5	1396141.BATP01000057_gene2939	3.759e-10	72.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	cqsA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K10915	ko00260,ko00780,ko01100,ko02024,ko05111,map00260,map00780,map01100,map02024,map05111	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding
CMS3_k127_6527669_1	1210884.HG799463_gene9849	1.078e-67	256.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IYT8@203682|Planctomycetes	2|Bacteria	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS3_k127_6527669_2	272134.KB731324_gene1938	6.451e-06	58.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1H8BH@1150|Oscillatoriales	1117|Cyanobacteria	CT	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HEAT_2,HEAT_PBS,NACHT
CMS3_k127_6527669_3	246197.MXAN_5783	0.0006045	51.0	COG4968@1|root,COG4968@2|Bacteria,1QXV9@1224|Proteobacteria,42VR9@68525|delta/epsilon subdivisions,2WRJV@28221|Deltaproteobacteria,2YW4P@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilin PilA	pilA	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
CMS3_k127_6527669_0	344747.PM8797T_05840	3.867e-141	460.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CMS3_k127_6538212_0	756272.Plabr_3928	1.071e-193	616.0	COG3119@1|root,COG3119@2|Bacteria,2J20N@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_6558961_59	999630.TUZN_0698	1.433e-08	58.0	COG0620@1|root,arCOG01876@2157|Archaea,2XPKF@28889|Crenarchaeota	28889|Crenarchaeota	E	Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS3_k127_6558961_39	28072.Nos7524_1448	1.228e-43	178.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1FZWQ@1117|Cyanobacteria,1HKIQ@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
CMS3_k127_6558961_46	1120949.KB903321_gene2711	1.591e-22	111.0	COG0438@1|root,COG2244@1|root,COG0438@2|Bacteria,COG2244@2|Bacteria,2GKEA@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_6558961_16	1121920.AUAU01000014_gene2803	3.319e-97	328.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_6558961_67	448385.sce5359	2.517e-05	58.0	COG4932@1|root,COG4932@2|Bacteria,1PYE0@1224|Proteobacteria,43E3U@68525|delta/epsilon subdivisions,2X97I@28221|Deltaproteobacteria,2Z2E0@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6558961_9	880070.Cycma_0177	6.106e-148	495.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6558961_56	1123242.JH636434_gene4550	4.533e-11	76.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6558961_49	1449350.OCH239_13095	4.788e-17	96.0	COG1361@1|root,COG2931@1|root,COG3055@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG4932@2|Bacteria,1PHZE@1224|Proteobacteria,2V8XK@28211|Alphaproteobacteria,4KND8@93682|Roseivivax	28211|Alphaproteobacteria	MQ	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF11,Malectin
CMS3_k127_6558961_37	234267.Acid_0985	1.137e-49	183.0	COG0652@1|root,COG0652@2|Bacteria,3Y7R6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS3_k127_6558961_35	1254432.SCE1572_07655	2.639e-51	207.0	COG0703@1|root,COG3620@1|root,COG0703@2|Bacteria,COG3620@2|Bacteria,1MX66@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	-	ko:K15546	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31,SKI
CMS3_k127_6558961_2	1254432.SCE1572_07650	2.607e-199	651.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS3_k127_6558961_4	391625.PPSIR1_36257	4.487e-193	616.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,437U1@68525|delta/epsilon subdivisions,2X33K@28221|Deltaproteobacteria,2YU2K@29|Myxococcales	28221|Deltaproteobacteria	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_6558961_54	545696.HOLDEFILI_02024	1.088e-12	72.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,3VPJ0@526524|Erysipelotrichia	526524|Erysipelotrichia	C	NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CMS3_k127_6558961_66	313606.M23134_05392	2.315e-05	47.0	COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,47NQU@768503|Cytophagia	976|Bacteroidetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS3_k127_6558961_14	1120972.AUMH01000007_gene1737	4.024e-103	346.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,278RW@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS3_k127_6558961_20	502025.Hoch_0553	6.443e-83	285.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,43AKH@68525|delta/epsilon subdivisions,2WW5J@28221|Deltaproteobacteria,2YV4B@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS3_k127_6558961_24	502025.Hoch_0552	6.143e-72	261.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,42S73@68525|delta/epsilon subdivisions,2WNPE@28221|Deltaproteobacteria,2YV3B@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS3_k127_6558961_51	98439.AJLL01000032_gene3171	3.156e-16	93.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1FZWQ@1117|Cyanobacteria,1JHGB@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_6558961_29	861299.J421_1115	2.727e-61	233.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6558961_34	1174528.JH992898_gene2659	1.596e-52	206.0	COG1216@1|root,COG1216@2|Bacteria,1G0X3@1117|Cyanobacteria,1JJG1@1189|Stigonemataceae	1117|Cyanobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
CMS3_k127_6558961_23	595460.RRSWK_02048	9.859e-74	260.0	COG0398@1|root,COG0398@2|Bacteria,2J2ZN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547,SNARE_assoc
CMS3_k127_6558961_7	435591.BDI_2321	4.169e-154	500.0	COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia	976|Bacteroidetes	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS3_k127_6558961_18	1304284.L21TH_2536	1.807e-89	309.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,36EMP@31979|Clostridiaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CMS3_k127_6558961_17	502025.Hoch_4694	2.428e-94	320.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2YUWH@29|Myxococcales	28221|Deltaproteobacteria	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
CMS3_k127_6558961_12	755732.Fluta_3528	9.501e-136	453.0	COG1233@1|root,COG1233@2|Bacteria,4P24Z@976|Bacteroidetes,1IITR@117743|Flavobacteriia	976|Bacteroidetes	C	COGs COG1233 Phytoene dehydrogenase and related protein	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_8
CMS3_k127_6558961_11	338963.Pcar_1732	3.439e-145	466.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,43V2E@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS3_k127_6558961_31	290397.Adeh_0749	2.661e-58	217.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,42ZKN@68525|delta/epsilon subdivisions,2WUTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_6558961_19	1313172.YM304_11670	1.859e-84	291.0	COG0235@1|root,COG0235@2|Bacteria,2GJ8W@201174|Actinobacteria	201174|Actinobacteria	G	Class II aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS3_k127_6558961_3	756272.Plabr_1705	2.075e-194	617.0	COG3119@1|root,COG3119@2|Bacteria,2IXZS@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CMS3_k127_6558961_22	1188256.BASI01000005_gene1574	1.236e-75	281.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2TSWI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	N6-adenine-specific DNA methylase	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	THUMP,UPF0020
CMS3_k127_6558961_43	1457250.BBMO01000001_gene1504	4.768e-30	133.0	COG0438@1|root,arCOG01403@2157|Archaea,2XWAX@28890|Euryarchaeota,23TPP@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_6558961_53	1304877.KI519400_gene373	2.662e-13	82.0	COG4641@1|root,COG4641@2|Bacteria,1R62R@1224|Proteobacteria,2TVHD@28211|Alphaproteobacteria,3JWFP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
CMS3_k127_6558961_44	1184267.A11Q_940	6.855e-29	123.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,431ED@68525|delta/epsilon subdivisions,2MU0R@213481|Bdellovibrionales,2WWZ0@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS3_k127_6558961_45	134676.ACPL_2099	1.225e-26	127.0	COG0535@1|root,COG0535@2|Bacteria,2GTTW@201174|Actinobacteria,4DIAW@85008|Micromonosporales	201174|Actinobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS3_k127_6558961_36	1128421.JAGA01000002_gene1228	8.534e-50	204.0	COG1801@1|root,COG1801@2|Bacteria,2NPRG@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_6558961_8	1254432.SCE1572_47340	4.835e-150	497.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,43203@68525|delta/epsilon subdivisions,2WWMI@28221|Deltaproteobacteria,2YTY1@29|Myxococcales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	cefD	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS3_k127_6558961_47	639030.JHVA01000001_gene743	8.527e-19	97.0	COG1664@1|root,COG1664@2|Bacteria,3Y5MK@57723|Acidobacteria,2JJXQ@204432|Acidobacteriia	204432|Acidobacteriia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS3_k127_6558961_13	344747.PM8797T_16018	2.494e-122	403.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26,3.2.1.65	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311	RC00028,RC00077,RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N,Glyco_hydro_43
CMS3_k127_6558961_42	391615.ABSJ01000057_gene1515	5.339e-38	153.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,1J6EJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	psrA	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS3_k127_6558961_28	715451.ambt_20900	1.888e-68	258.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMP5@1236|Gammaproteobacteria,466Q6@72275|Alteromonadaceae	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_6558961_21	1122613.ATUP01000001_gene1987	2.402e-82	289.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,2VF2W@28211|Alphaproteobacteria,43WSP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS3_k127_6558961_1	1125863.JAFN01000001_gene912	5.435e-291	929.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS3_k127_6558961_10	1123256.KB907947_gene2652	3.021e-146	474.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_6558961_5	331869.BAL199_28445	1.292e-171	547.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,4BPGN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	HflC and HflK could regulate a protease	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_6558961_6	331869.BAL199_28440	2.014e-162	522.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,4BP7N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS3_k127_6558961_30	314230.DSM3645_21122	1.676e-59	212.0	2EPE8@1|root,33H0U@2|Bacteria,2J3C3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6558961_55	1210884.HG799477_gene15444	3.735e-11	76.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_6558961_50	502025.Hoch_2482	2.404e-16	93.0	COG0737@1|root,COG0737@2|Bacteria,1NDBC@1224|Proteobacteria,42V2W@68525|delta/epsilon subdivisions,2WS9M@28221|Deltaproteobacteria,2YV8Z@29|Myxococcales	28221|Deltaproteobacteria	F	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_6558961_62	517418.Ctha_2110	2.673e-07	64.0	COG0526@1|root,COG0526@2|Bacteria,1FE88@1090|Chlorobi	1090|Chlorobi	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_6558961_40	1254432.SCE1572_32710	1.486e-42	175.0	COG0683@1|root,COG2010@1|root,COG0683@2|Bacteria,COG2010@2|Bacteria,1R4K1@1224|Proteobacteria,42Z9W@68525|delta/epsilon subdivisions,2WUMZ@28221|Deltaproteobacteria,2YTTR@29|Myxococcales	28221|Deltaproteobacteria	C	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Peripla_BP_6
CMS3_k127_6558961_41	215803.DB30_5882	1.582e-41	160.0	COG1999@1|root,COG1999@2|Bacteria,1N19Q@1224|Proteobacteria,42XV1@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_6558961_26	378806.STAUR_4614	1.849e-69	261.0	COG3391@1|root,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2X34S@28221|Deltaproteobacteria,2YU9J@29|Myxococcales	28221|Deltaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
CMS3_k127_6558961_0	215803.DB30_8297	0.0	1170.0	COG2132@1|root,COG2132@2|Bacteria,1N9H3@1224|Proteobacteria,437UT@68525|delta/epsilon subdivisions,2WYPB@28221|Deltaproteobacteria,2YUNB@29|Myxococcales	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22349	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS3_k127_6558961_65	1343740.M271_26920	2.169e-05	55.0	COG2197@1|root,COG2197@2|Bacteria,2I126@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6558961_33	1265313.HRUBRA_01685	2.661e-55	209.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,1J4IT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675	RsgA_GTPase
CMS3_k127_6558961_64	1463861.JNXE01000047_gene8592	2.056e-05	57.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,2GW8H@201174|Actinobacteria	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS3_k127_6558961_52	247490.KSU1_C0387	5.346e-16	91.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
CMS3_k127_6558961_58	1123508.JH636441_gene3315	1.305e-09	72.0	2DY40@1|root,34816@2|Bacteria,2J43P@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS3_k127_6558961_27	235909.GK1597	1.671e-68	252.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1WFD8@129337|Geobacillus	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	yngJ	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6558961_63	518766.Rmar_0756	5.049e-07	62.0	COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,1FIMM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	SurA N-terminal domain	ppiD	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2
CMS3_k127_6558961_25	237368.SCABRO_03425	3.518e-71	249.0	COG0463@1|root,COG0463@2|Bacteria,2IZV0@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6558961_48	391625.PPSIR1_37349	3.62e-17	98.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_6558961_57	1297742.A176_00134	1.304e-10	77.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6558961_32	404589.Anae109_2325	2.935e-58	229.0	COG1572@1|root,COG2885@1|root,COG2911@1|root,COG3209@1|root,COG1572@2|Bacteria,COG2885@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,1PFUJ@1224|Proteobacteria,430XP@68525|delta/epsilon subdivisions,2WW66@28221|Deltaproteobacteria	2|Bacteria	M	TIGRFAM YD repeat protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Calx-beta,DctA-YdbH,RHS_repeat
CMS3_k127_6558961_38	1191523.MROS_0332	9.23e-48	198.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_6558961_60	204669.Acid345_1602	2.841e-08	64.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS3_k127_6581053_0	309807.SRU_0691	1.041e-182	601.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1FIND@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	homoserine dehydrogenase	-	-	1.1.1.3,2.7.2.4	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7,Homoserine_dh,NAD_binding_3
CMS3_k127_6581053_5	1121456.ATVA01000011_gene1703	1.667e-24	112.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria,2MCVG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS3_k127_6581053_4	1177928.TH2_07611	3.294e-56	217.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,2JPN0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS3_k127_6581053_2	1262914.BN533_00117	1.638e-90	309.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4H1XK@909932|Negativicutes	909932|Negativicutes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_6581053_3	1280390.CBQR020000169_gene4486	3.533e-62	243.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,4HBMK@91061|Bacilli,26U2U@186822|Paenibacillaceae	91061|Bacilli	S	AIR carboxylase	larB	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS3_k127_6581053_1	1340493.JNIF01000003_gene3611	1.289e-117	390.0	COG0505@1|root,COG0505@2|Bacteria,3Y31Y@57723|Acidobacteria	57723|Acidobacteria	EF	TIGRFAM Carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS3_k127_6612362_0	525904.Tter_0987	2.768e-167	536.0	COG2115@1|root,COG2115@2|Bacteria,2NQDI@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	xylA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_6612362_1	278957.ABEA03000179_gene2883	1.33e-115	404.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS3_k127_6612362_2	32057.KB217478_gene3544	2.329e-06	61.0	COG1413@1|root,COG1413@2|Bacteria,1GHRB@1117|Cyanobacteria,1HSJZ@1161|Nostocales	1117|Cyanobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_6621016_1	243090.RB12567	2.98e-104	351.0	COG2010@1|root,COG3064@1|root,COG2010@2|Bacteria,COG3064@2|Bacteria,2IXU7@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS3_k127_6621016_0	1123508.JH636441_gene3094	1.375e-243	759.0	COG4102@1|root,COG4102@2|Bacteria,2IXNP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6621016_2	886293.Sinac_7534	2.849e-70	260.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6641607_1	1415756.JQMY01000001_gene3222	5.653e-91	304.0	COG5482@1|root,COG5482@2|Bacteria,1MWIN@1224|Proteobacteria,2TS4R@28211|Alphaproteobacteria,2PDYG@252301|Oceanicola	28211|Alphaproteobacteria	S	Putative PD-(D/E)XK phosphodiesterase (DUF2161)	MA20_28540	-	-	-	-	-	-	-	-	-	-	-	DUF2161
CMS3_k127_6641607_2	1121106.JQKB01000034_gene5982	1.943e-60	226.0	COG0265@1|root,COG0265@2|Bacteria,1N58P@1224|Proteobacteria,2TTTZ@28211|Alphaproteobacteria,2JS01@204441|Rhodospirillales	204441|Rhodospirillales	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_6641607_4	545694.TREPR_2995	0.0003499	54.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_C14,WD40
CMS3_k127_6641607_0	756272.Plabr_1607	2.254e-178	578.0	COG3119@1|root,COG3119@2|Bacteria,2J2PQ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS3_k127_6641607_3	706191.PANA_3669	2.297e-09	63.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,3VY03@53335|Pantoea	1236|Gammaproteobacteria	U	to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS3_k127_66604_3	1206744.BAGL01000126_gene6190	1.451e-50	200.0	COG3055@1|root,COG3055@2|Bacteria,2GK14@201174|Actinobacteria,4FUXU@85025|Nocardiaceae	201174|Actinobacteria	Q	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,FG-GAP,VCBS
CMS3_k127_66604_6	1341646.CBMO010000059_gene1677	9.917e-09	64.0	COG0664@1|root,COG0664@2|Bacteria,2IF4P@201174|Actinobacteria,237B5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20
CMS3_k127_66604_7	861299.J421_4314	2.394e-08	56.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20,cNMP_binding
CMS3_k127_66604_4	1123242.JH636434_gene5531	2.679e-34	151.0	2EUN2@1|root,33N3X@2|Bacteria,2J1AF@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_66604_0	886293.Sinac_0924	3.132e-115	400.0	COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
CMS3_k127_66604_5	287986.DV20_02900	2.051e-17	98.0	COG1595@1|root,COG1595@2|Bacteria,2GM8T@201174|Actinobacteria,4DY2F@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_66604_1	886293.Sinac_6694	4.067e-84	317.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_6692602_5	880073.Calab_2466	1.201e-130	426.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS3_k127_6692602_8	1123242.JH636434_gene5414	4.085e-100	335.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS3_k127_6692602_19	1123242.JH636434_gene5413	6.214e-39	166.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6692602_13	1123242.JH636434_gene5412	4.053e-67	245.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS3_k127_6692602_18	1265505.ATUG01000002_gene2733	6.33e-40	173.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
CMS3_k127_6692602_21	1499967.BAYZ01000152_gene1397	7.044e-21	111.0	COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria	2|Bacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS3_k127_6692602_20	595460.RRSWK_05269	3.888e-23	108.0	COG1226@1|root,32Y28@2|Bacteria,2J0V4@203682|Planctomycetes	203682|Planctomycetes	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
CMS3_k127_6692602_16	1499967.BAYZ01000106_gene3543	2.783e-46	190.0	COG0535@1|root,COG0826@1|root,COG0535@2|Bacteria,COG0826@2|Bacteria	2|Bacteria	O	peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Radical_SAM
CMS3_k127_6692602_10	1049564.TevJSym_aq00670	3.242e-81	286.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS3_k127_6692602_12	1049564.TevJSym_aq00680	1.286e-70	255.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfE2	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS3_k127_6692602_15	1049564.TevJSym_aq00690	1.056e-52	198.0	COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
CMS3_k127_6692602_6	1049564.TevJSym_aq00700	1.794e-113	397.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS3_k127_6692602_2	1049564.TevJSym_aq00710	3.808e-168	553.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
CMS3_k127_6692602_1	1049564.TevJSym_aq00810	6.652e-210	717.0	COG0674@1|root,COG1013@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	forE	-	1.2.7.1	ko:K00171,ko:K00172,ko:K02573,ko:K03737,ko:K13795,ko:K18930	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,Fer4,Fer4_4,Fer4_6,Fer4_9,Nitroreductase,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS3_k127_6692602_9	1049564.TevJSym_bb00010	9.88e-100	352.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
CMS3_k127_6692602_4	1049564.TevJSym_bb00030	1.766e-131	452.0	COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CMS3_k127_6692602_3	1049564.TevJSym_bb00040	2.837e-133	431.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS3_k127_6692602_0	1049564.TevJSym_bb00050	1.432e-253	798.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_6692602_7	330214.NIDE0351	1.098e-110	391.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	MA20_43810	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS3_k127_6692602_11	1304883.KI912532_gene2659	1.231e-71	253.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,2KUMK@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_6692602_17	1288963.ADIS_0690	1.097e-42	165.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,47P77@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS3_k127_6692602_23	1123508.JH636442_gene4266	2.924e-07	53.0	COG2128@1|root,COG2128@2|Bacteria,2IZDY@203682|Planctomycetes	203682|Planctomycetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6692602_22	1123508.JH636442_gene4266	1.688e-12	79.0	COG2128@1|root,COG2128@2|Bacteria,2IZDY@203682|Planctomycetes	203682|Planctomycetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_6692602_14	518766.Rmar_1383	7.151e-61	221.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	2|Bacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,DUF4396
CMS3_k127_6713190_7	1227739.Hsw_0771	6.455e-28	130.0	COG4631@1|root,COG4631@2|Bacteria,4PMEG@976|Bacteroidetes,47KPG@768503|Cytophagia	976|Bacteroidetes	F	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS3_k127_6713190_1	714943.Mucpa_6423	9.017e-116	401.0	COG4630@1|root,COG4630@2|Bacteria,4NI8H@976|Bacteroidetes,1IQYJ@117747|Sphingobacteriia	976|Bacteroidetes	F	PFAM 2Fe-2S -binding	-	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
CMS3_k127_6713190_4	13035.Dacsa_3298	1.978e-69	243.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
CMS3_k127_6713190_3	338963.Pcar_0606	1.057e-104	362.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,43S4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS3_k127_6713190_6	357808.RoseRS_2381	6.15e-41	162.0	COG0279@1|root,COG0279@2|Bacteria,2G6QD@200795|Chloroflexi,375VE@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS3_k127_6713190_0	555088.DealDRAFT_0480	6.685e-165	538.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42KH3@68298|Syntrophomonadaceae	186801|Clostridia	H	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_6713190_2	886293.Sinac_2608	1.947e-111	372.0	COG0075@1|root,COG0075@2|Bacteria,2IYEK@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS3_k127_6713190_5	530564.Psta_0956	8.436e-47	192.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS3_k127_6713190_10	203124.Tery_5036	0.0008495	51.0	COG0457@1|root,COG0457@2|Bacteria,1G0BJ@1117|Cyanobacteria,1H956@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS3_k127_6713190_9	272631.ML1076	3.966e-06	57.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria,2343I@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6713190_8	497964.CfE428DRAFT_4021	3.584e-10	64.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS3_k127_6728833_15	269796.Rru_A3125	0.0003034	46.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2JQ88@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_6728833_0	1356852.N008_03025	7.703e-175	576.0	COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,47P67@768503|Cytophagia	976|Bacteroidetes	E	Dipeptidyl peptidase IV (DPP IV) N-terminal region	ptpA	-	3.4.14.12,3.4.14.5	ko:K01278,ko:K18574	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_6728833_9	767817.Desgi_0178	1.341e-53	199.0	COG2197@1|root,COG2197@2|Bacteria,1TSBV@1239|Firmicutes,25BWE@186801|Clostridia	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6728833_12	331869.BAL199_20225	3.612e-26	125.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2UHJU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
CMS3_k127_6728833_13	1254432.SCE1572_12065	5.943e-25	121.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,42UJ1@68525|delta/epsilon subdivisions,2WR2I@28221|Deltaproteobacteria,2YZRT@29|Myxococcales	28221|Deltaproteobacteria	S	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS3_k127_6728833_4	1111479.AXAR01000006_gene758	3.069e-113	399.0	COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate	yvfW	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
CMS3_k127_6728833_8	1048834.TC41_0687	2.474e-62	226.0	COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
CMS3_k127_6728833_5	66377.JOBH01000002_gene716	3.074e-107	376.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria	201174|Actinobacteria	G	D-galactarate dehydratase Altronate	-	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
CMS3_k127_6728833_6	1210884.HG799478_gene15504	8.675e-78	271.0	COG0451@1|root,COG0451@2|Bacteria,2IYKN@203682|Planctomycetes	203682|Planctomycetes	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS3_k127_6728833_1	530564.Psta_0761	5.393e-155	505.0	COG1902@1|root,COG1902@2|Bacteria,2IXBM@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS3_k127_6728833_10	1173028.ANKO01000106_gene309	1.648e-52	213.0	COG0727@1|root,COG0727@2|Bacteria,1G3ZQ@1117|Cyanobacteria,1HAC7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6728833_2	530564.Psta_2650	9.607e-136	443.0	COG0579@1|root,COG0579@2|Bacteria,2IX3W@203682|Planctomycetes	203682|Planctomycetes	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
CMS3_k127_6728833_7	575540.Isop_0185	7.208e-72	253.0	COG1686@1|root,COG2367@1|root,COG3409@1|root,COG1686@2|Bacteria,COG2367@2|Bacteria,COG3409@2|Bacteria,2IY9N@203682|Planctomycetes	203682|Planctomycetes	M	PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase2,PG_binding_1,Peptidase_S11
CMS3_k127_6728833_14	1499967.BAYZ01000159_gene534	4.458e-20	102.0	2DBXQ@1|root,2ZBQY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
CMS3_k127_6728833_3	215803.DB30_3103	6.249e-128	442.0	COG3525@1|root,COG3525@2|Bacteria,1MVDE@1224|Proteobacteria,42YD5@68525|delta/epsilon subdivisions,2X313@28221|Deltaproteobacteria,2YTXH@29|Myxococcales	28221|Deltaproteobacteria	G	Putative carbohydrate binding domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX,CHB_HEX_C,Glyco_hydro_20,Glyco_hydro_20b
CMS3_k127_6728833_11	1122222.AXWR01000040_gene631	3.182e-36	148.0	COG0153@1|root,COG0153@2|Bacteria,1WIIN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS3_k127_6748444_0	1343740.M271_17280	0.00012	55.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
CMS3_k127_6761029_4	518766.Rmar_1420	1.309e-130	453.0	COG1228@1|root,COG1228@2|Bacteria,4P0AG@976|Bacteroidetes,1FJ21@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_6761029_3	518766.Rmar_1421	9.024e-154	518.0	COG1228@1|root,COG1228@2|Bacteria,4P07N@976|Bacteroidetes,1FISQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6761029_2	1122939.ATUD01000001_gene577	2.729e-174	580.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6761029_15	1304874.JAFY01000002_gene850	2.632e-39	166.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS3_k127_6761029_28	1479237.JMLY01000001_gene1521	0.0001134	55.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6761029_6	1210884.HG799471_gene14563	2.553e-73	281.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6761029_11	767817.Desgi_2857	4.557e-54	205.0	COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia	186801|Clostridia	M	Exopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS3_k127_6761029_17	926550.CLDAP_16970	2.683e-26	114.0	COG3576@1|root,COG3576@2|Bacteria,2G8P8@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS3_k127_6761029_5	525904.Tter_1666	3.5e-84	301.0	COG0497@1|root,COG0497@2|Bacteria,2NNUS@2323|unclassified Bacteria	2|Bacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03631,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
CMS3_k127_6761029_24	1122963.AUHB01000010_gene1686	8.26e-09	68.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,370P8@31993|Methylocystaceae	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CMS3_k127_6761029_14	1183438.GKIL_2133	2.526e-42	173.0	COG4872@1|root,COG4872@2|Bacteria,1G2MS@1117|Cyanobacteria	1117|Cyanobacteria	P	membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS3_k127_6761029_16	459495.SPLC1_S600310	2.175e-26	115.0	COG4929@1|root,COG4929@2|Bacteria,1G74M@1117|Cyanobacteria,1H9U1@1150|Oscillatoriales	1117|Cyanobacteria	S	membrane-anchored protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
CMS3_k127_6761029_22	67373.JOBF01000003_gene551	4.859e-15	90.0	COG0477@1|root,COG4932@1|root,COG0477@2|Bacteria,COG4932@2|Bacteria,2GKQH@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
CMS3_k127_6761029_23	762963.HMPREF9056_00308	6.825e-10	73.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4D4ET@85005|Actinomycetales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_6761029_7	1123360.thalar_02888	1.368e-71	267.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2UQID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,FlpD
CMS3_k127_6761029_21	395495.Lcho_0048	9.189e-16	88.0	COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VMIP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_6761029_26	522306.CAP2UW1_1790	2.354e-05	48.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2VJ1N@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase subunit I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS3_k127_6761029_1	608538.HTH_0153	1.035e-186	597.0	COG0843@1|root,COG0843@2|Bacteria	2|Bacteria	C	heme-copper terminal oxidase activity	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS3_k127_6761029_10	1244869.H261_01552	2.553e-55	198.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2UJSY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome c oxidase (Subunit II)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6761029_8	870187.Thini_0877	1.997e-67	246.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,1SKBI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CMS3_k127_6761029_0	264462.Bd2608	1.413e-208	658.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria	1224|Proteobacteria	Q	Nitrite reductase	nirK	-	1.3.3.5,1.7.2.1	ko:K00368,ko:K08100	ko00860,ko00910,ko01110,ko01120,map00860,map00910,map01110,map01120	M00529	R00783,R00785,R02394	RC00086,RC01983	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3
CMS3_k127_6761029_9	497964.CfE428DRAFT_3241	7.939e-67	240.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_6761029_12	497964.CfE428DRAFT_3242	5.257e-44	169.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_6761029_19	1121920.AUAU01000008_gene1592	6.496e-18	89.0	COG1959@1|root,COG1959@2|Bacteria,3Y8ZE@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS3_k127_6761029_29	1283299.AUKG01000001_gene2973	0.0002017	53.0	COG1749@1|root,COG3525@1|root,COG4257@1|root,COG4733@1|root,COG1749@2|Bacteria,COG3525@2|Bacteria,COG4257@2|Bacteria,COG4733@2|Bacteria,2I2X3@201174|Actinobacteria,4CSIX@84995|Rubrobacteria	84995|Rubrobacteria	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,fn3
CMS3_k127_6761029_27	33876.JNXY01000027_gene3566	8.193e-05	56.0	COG1680@1|root,COG1680@2|Bacteria,2GN1H@201174|Actinobacteria,4DG6P@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_6761029_18	639030.JHVA01000001_gene3381	3.764e-22	107.0	2B33H@1|root,31VR5@2|Bacteria,3Y819@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6781204_6	96561.Dole_2588	8.126e-12	69.0	COG1807@1|root,COG1807@2|Bacteria,1RK4G@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6781204_0	1500890.JQNL01000001_gene1485	2.87e-80	287.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,1X40U@135614|Xanthomonadales	135614|Xanthomonadales	J	Oxidoreductase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS3_k127_6781204_4	1278073.MYSTI_07189	9.838e-44	177.0	28M67@1|root,31CRD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6781204_8	323261.Noc_1689	3.287e-10	68.0	2EB0T@1|root,3351P@2|Bacteria,1NCHM@1224|Proteobacteria,1SJ6Z@1236|Gammaproteobacteria,1X1WX@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6781204_3	575540.Isop_0996	4.79e-48	194.0	COG0367@1|root,COG0367@2|Bacteria,2J23D@203682|Planctomycetes	203682|Planctomycetes	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_6781204_5	358823.DF19_26255	2.166e-41	174.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS3_k127_6781204_7	1172181.KB911727_gene4848	1.31e-11	78.0	COG0500@1|root,COG1051@1|root,COG1051@2|Bacteria,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,NUDIX
CMS3_k127_6781204_9	742733.HMPREF9469_04350	0.0002782	53.0	COG3533@1|root,COG3533@2|Bacteria,1TRXQ@1239|Firmicutes,24BS8@186801|Clostridia,222HH@1506553|Lachnoclostridium	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
CMS3_k127_6781204_2	941449.dsx2_3386	3.25e-49	201.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria,2M7ZS@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_6781204_1	391625.PPSIR1_31633	2.184e-73	254.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
CMS3_k127_6798927_4	67257.JODR01000001_gene918	3.687e-139	455.0	COG1362@1|root,COG1362@2|Bacteria,2GKW4@201174|Actinobacteria	201174|Actinobacteria	E	M18 family aminopeptidase	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
CMS3_k127_6798927_17	1380355.JNIJ01000005_gene2700	5.71e-19	97.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,3JUS4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S9
CMS3_k127_6798927_28	1229204.AMYY01000003_gene970	1.552e-07	65.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,4BSSY@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Sigma-70, region 4	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6798927_24	247490.KSU1_C0387	1.135e-08	67.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
CMS3_k127_6798927_15	313589.JNB_03760	1.92e-42	177.0	COG0500@1|root,COG2226@2|Bacteria,2IMHF@201174|Actinobacteria,4FIRA@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_6798927_21	1238182.C882_4356	5.506e-14	86.0	COG1600@1|root,COG1600@2|Bacteria,1R9XX@1224|Proteobacteria,2UA5Q@28211|Alphaproteobacteria,2JSJ4@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1145 Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6798927_26	1297742.A176_07375	4.596e-08	67.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6798927_29	1385510.N781_09540	2.17e-06	62.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1UXD9@1239|Firmicutes,4I2J1@91061|Bacilli,2YBSI@289201|Pontibacillus	91061|Bacilli	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6798927_22	383372.Rcas_1796	8.958e-14	82.0	COG4848@1|root,COG4848@2|Bacteria,2GAD2@200795|Chloroflexi,375H8@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1444)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1444
CMS3_k127_6798927_13	588581.Cpap_3222	3.678e-64	242.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WGVY@541000|Ruminococcaceae	186801|Clostridia	E	aminotransferase class V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_6798927_0	237368.SCABRO_00503	7.399e-259	842.0	COG0249@1|root,COG0249@2|Bacteria,2IXGV@203682|Planctomycetes	203682|Planctomycetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS3_k127_6798927_27	1270196.JCKI01000008_gene1643	6.636e-08	64.0	COG0795@1|root,COG0795@2|Bacteria,4NF8Y@976|Bacteroidetes	976|Bacteroidetes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS3_k127_6798927_31	1121440.AUMA01000006_gene1598	0.0003097	53.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,2M8M1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS3_k127_6798927_32	1122194.AUHU01000006_gene622	0.0007555	52.0	COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,466MU@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
CMS3_k127_6798927_19	103733.JNYO01000019_gene2102	2.336e-14	88.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4E4HQ@85010|Pseudonocardiales	201174|Actinobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS3_k127_6798927_30	391625.PPSIR1_10585	3.877e-05	57.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS3_k127_6798927_11	1192034.CAP_6202	4.848e-78	275.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,HTH_8,Sigma54_activat
CMS3_k127_6798927_3	398767.Glov_0481	2.355e-165	545.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS3_k127_6798927_1	314230.DSM3645_19883	3.882e-217	686.0	COG0069@1|root,COG0069@2|Bacteria,2J28V@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the glutamate synthase family	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
CMS3_k127_6798927_23	856793.MICA_1644	2.181e-13	82.0	COG1520@1|root,COG3533@1|root,COG1520@2|Bacteria,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,DUF4832,Laminin_G_3,PQQ_2,PQQ_3
CMS3_k127_6798927_16	1123248.KB893322_gene687	9.095e-37	160.0	COG2931@1|root,COG4733@1|root,COG2931@2|Bacteria,COG4733@2|Bacteria,4NKF1@976|Bacteroidetes	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
CMS3_k127_6798927_5	1123508.JH636441_gene3216	2.448e-126	422.0	28MB6@1|root,2ZAPQ@2|Bacteria,2IWSP@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6798927_8	290397.Adeh_3088	3.804e-105	368.0	COG5557@1|root,COG5557@2|Bacteria,1R7R0@1224|Proteobacteria,42P0Z@68525|delta/epsilon subdivisions,2X7KR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
CMS3_k127_6798927_14	316067.Geob_1016	1.849e-60	225.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,43T2N@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
CMS3_k127_6798927_20	1167006.UWK_02289	2.718e-14	83.0	2EE9W@1|root,32HRH@2|Bacteria,1Q1IP@1224|Proteobacteria,437AK@68525|delta/epsilon subdivisions,2X2EY@28221|Deltaproteobacteria,2MNPN@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6798927_7	314230.DSM3645_15540	6.771e-111	377.0	COG0820@1|root,COG0820@2|Bacteria,2J228@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the radical SAM superfamily. RlmN family	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS3_k127_6798927_12	118168.MC7420_3512	2.109e-77	267.0	COG4636@1|root,COG4636@2|Bacteria,1G0VC@1117|Cyanobacteria,1H81E@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS3_k127_6798927_9	1122179.KB890435_gene931	1.072e-94	342.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_6798927_25	756499.Desde_1098	2.292e-08	62.0	COG1652@1|root,COG1652@2|Bacteria,1V4J4@1239|Firmicutes,25DK3@186801|Clostridia,262ES@186807|Peptococcaceae	186801|Clostridia	S	LysM domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS3_k127_6798927_6	886293.Sinac_5868	8.626e-119	391.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS3_k127_6798927_2	314230.DSM3645_07445	6.894e-171	550.0	COG0124@1|root,COG0124@2|Bacteria,2IY1U@203682|Planctomycetes	203682|Planctomycetes	J	tRNA synthetase class II	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS3_k127_6798927_18	1396418.BATQ01000064_gene1597	6.385e-19	100.0	2E533@1|root,32ZW9@2|Bacteria,46X7Y@74201|Verrucomicrobia,2IUXW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6798927_10	391625.PPSIR1_29518	2.483e-93	322.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42S9C@68525|delta/epsilon subdivisions,2WM4G@28221|Deltaproteobacteria,2YU8Y@29|Myxococcales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	dlhH2	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS3_k127_6804414_0	1122921.KB898191_gene2007	1.415e-43	177.0	COG0457@1|root,COG3210@1|root,COG5492@1|root,COG0457@2|Bacteria,COG3210@2|Bacteria,COG5492@2|Bacteria,1UI3P@1239|Firmicutes,4HJMZ@91061|Bacilli,27713@186822|Paenibacillaceae	2|Bacteria	GN	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Cadherin-like,CarboxypepD_reg,Flg_new,Laminin_G_3,PATR,SLH,fn3
CMS3_k127_6804414_1	33905.BTHE_2001	1.62e-20	95.0	COG1254@1|root,COG1254@2|Bacteria,2HZRI@201174|Actinobacteria,4D1EM@85004|Bifidobacteriales	201174|Actinobacteria	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS3_k127_6804414_2	983920.Y88_3102	2.075e-10	74.0	COG1595@1|root,COG1595@2|Bacteria,1NRNT@1224|Proteobacteria,2TT5K@28211|Alphaproteobacteria,2KAWV@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6805064_12	314345.SPV1_02422	3.506e-78	294.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria	1224|Proteobacteria	E	the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia	allC	GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009442,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0017144,GO:0030145,GO:0034641,GO:0042737,GO:0043167,GO:0043169,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047652,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iECH74115_1262.ECH74115_0617,iECSP_1301.ECSP_0590,iECUMN_1333.ECUMN_0556,iECs_1301.ECs0578,iZ_1308.Z0671	M20_dimer,Peptidase_M20,Peptidase_M28
CMS3_k127_6805064_0	713587.THITH_17230	4.984e-288	899.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WX1S@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS3_k127_6805064_4	713586.KB900536_gene2298	3.869e-146	473.0	COG0540@1|root,COG0540@2|Bacteria,1R3Q5@1224|Proteobacteria,1RYCN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the ATCase OTCase family	-	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS3_k127_6805064_2	765914.ThisiDRAFT_2322	8.028e-197	625.0	COG0591@1|root,COG0591@2|Bacteria,1N8H2@1224|Proteobacteria,1RR54@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS3_k127_6805064_30	1158165.KB898871_gene2408	1.638e-09	69.0	2EK1K@1|root,33DS2@2|Bacteria,1NI6I@1224|Proteobacteria,1SH8F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6805064_28	1247963.JPHU01000004_gene573	6.631e-14	80.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_6805064_6	313628.LNTAR_09664	4.159e-105	359.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_6805064_26	190650.CC_1973	1.981e-18	100.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2KGDT@204458|Caulobacterales	204458|Caulobacterales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS3_k127_6805064_25	1105031.HMPREF1141_2101	4.523e-21	110.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,36E56@31979|Clostridiaceae	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6805064_15	1122602.ATXP01000002_gene693	1.161e-63	236.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,1W8Q4@1268|Micrococcaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6805064_16	575540.Isop_1260	4.451e-60	235.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	2|Bacteria	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6805064_13	575540.Isop_1259	3.94e-71	272.0	COG1228@1|root,COG1228@2|Bacteria,2IYFS@203682|Planctomycetes	203682|Planctomycetes	Q	COG1228 Imidazolonepropionase and related	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_6805064_7	575540.Isop_1258	6.191e-91	331.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_6805064_9	575540.Isop_1258	2.3e-83	308.0	COG1228@1|root,COG1228@2|Bacteria,2J0GA@203682|Planctomycetes	203682|Planctomycetes	Q	COGs COG1228 Imidazolonepropionase and related amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_6805064_27	928724.SacglDRAFT_03738	3.505e-17	95.0	COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,4DYC4@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS3_k127_6805064_22	575540.Isop_1256	8.71e-37	162.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Ribonuc_L-PSP
CMS3_k127_6805064_21	886293.Sinac_7396	4.877e-37	161.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_6805064_29	1242864.D187_007053	9.003e-11	76.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6805064_20	997346.HMPREF9374_3130	3.667e-37	151.0	COG1073@1|root,COG1073@2|Bacteria,1V1RV@1239|Firmicutes,4HGDR@91061|Bacilli,27B3I@186824|Thermoactinomycetaceae	91061|Bacilli	S	alpha/beta hydrolase fold	M1-904	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
CMS3_k127_6805064_5	1131269.AQVV01000028_gene28	1.449e-124	431.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
CMS3_k127_6805064_18	391625.PPSIR1_00465	2.071e-39	164.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
CMS3_k127_6805064_1	497964.CfE428DRAFT_2264	2.012e-207	655.0	COG3119@1|root,COG3119@2|Bacteria,46UNC@74201|Verrucomicrobia	2|Bacteria	P	Domain of unknown function (DUF4976)	mdsA	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_6805064_24	351160.LRC48	1.333e-23	115.0	COG3372@1|root,arCOG04356@2157|Archaea,2XSTX@28890|Euryarchaeota,2N95G@224756|Methanomicrobia	224756|Methanomicrobia	L	Protein of unknown function (DUF790)	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
CMS3_k127_6805064_11	368408.Tpen_1762	1.692e-80	287.0	COG1061@1|root,arCOG00874@2157|Archaea,2XQ1C@28889|Crenarchaeota	28889|Crenarchaeota	K	Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,Helicase_C,ResIII
CMS3_k127_6805064_17	756272.Plabr_3209	5.991e-55	210.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_6805064_8	756272.Plabr_3170	4.677e-87	304.0	COG3119@1|root,COG3119@2|Bacteria,2J2AM@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS3_k127_6805064_14	234267.Acid_3938	7.172e-67	257.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS3_k127_6805064_3	1380391.JIAS01000019_gene1121	2.213e-186	613.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS3_k127_6805064_23	1123508.JH636448_gene7570	2.407e-25	110.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS3_k127_6805064_19	1123508.JH636443_gene4728	1.016e-37	163.0	COG4219@1|root,COG4219@2|Bacteria,2J24Z@203682|Planctomycetes	203682|Planctomycetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS3_k127_6818150_26	1123242.JH636435_gene2223	1.125e-35	158.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
CMS3_k127_6818150_51	1123508.JH636453_gene5802	0.0008021	51.0	COG3210@1|root,COG3391@1|root,COG3827@1|root,COG4932@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3827@2|Bacteria,COG4932@2|Bacteria,2IY8U@203682|Planctomycetes	203682|Planctomycetes	M	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_6818150_5	1129794.C427_1223	2.323e-136	465.0	COG2706@1|root,COG3391@1|root,COG3637@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,COG3637@2|Bacteria,1QWRQ@1224|Proteobacteria,1T4S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_6	313628.LNTAR_08001	7.249e-108	359.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_35	69395.JQLZ01000001_gene2590	1.205e-13	80.0	2EQH5@1|root,33I35@2|Bacteria,1N2B2@1224|Proteobacteria,2UDX4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_44	44056.XP_009038388.1	2.781e-09	68.0	COG0596@1|root,KOG2564@2759|Eukaryota	2759|Eukaryota	Q	protein methylesterase activity	PPME1	GO:0000086,GO:0000278,GO:0000313,GO:0000314,GO:0002028,GO:0003674,GO:0003735,GO:0003824,GO:0004857,GO:0004864,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006464,GO:0006482,GO:0006518,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008214,GO:0009058,GO:0009059,GO:0009636,GO:0009892,GO:0009987,GO:0010467,GO:0010563,GO:0010605,GO:0010921,GO:0010923,GO:0010959,GO:0015935,GO:0016787,GO:0016788,GO:0019208,GO:0019212,GO:0019220,GO:0019222,GO:0019538,GO:0019888,GO:0019899,GO:0019900,GO:0019901,GO:0019902,GO:0019903,GO:0022402,GO:0030091,GO:0030234,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032515,GO:0032543,GO:0032879,GO:0032991,GO:0034641,GO:0034645,GO:0035303,GO:0035304,GO:0035305,GO:0035308,GO:0036211,GO:0042221,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043412,GO:0043603,GO:0043604,GO:0043666,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044839,GO:0045936,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051716,GO:0051721,GO:0051722,GO:0051723,GO:0052689,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0070887,GO:0070988,GO:0071704,GO:0080090,GO:0097237,GO:0098754,GO:0098772,GO:0098798,GO:0140053,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1903047,GO:1990577,GO:1990748,GO:1990904	3.1.1.89	ko:K13617	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abhydrolase_6
CMS3_k127_6818150_38	886293.Sinac_2761	6.265e-13	81.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IYTQ@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16
CMS3_k127_6818150_7	595460.RRSWK_04778	6.244e-102	367.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
CMS3_k127_6818150_32	1499967.BAYZ01000095_gene4206	8.672e-25	122.0	COG1262@1|root,COG2304@1|root,COG1262@2|Bacteria,COG2304@2|Bacteria,2NR84@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FGE-sulfatase,HSP70,PEGA,Peptidase_C14,Pkinase,VWA
CMS3_k127_6818150_33	247490.KSU1_C1440	1.565e-20	103.0	2DSS0@1|root,33H81@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
CMS3_k127_6818150_31	382464.ABSI01000013_gene1822	2.316e-27	123.0	COG2227@1|root,COG2227@2|Bacteria,46VSI@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS3_k127_6818150_22	521674.Plim_1811	1.091e-57	226.0	COG0265@1|root,COG0265@2|Bacteria,2IY6F@203682|Planctomycetes	203682|Planctomycetes	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_6818150_34	999541.bgla_1g03900	1.887e-20	106.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,1K0VU@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_6818150_15	530564.Psta_2723	2.83e-67	251.0	COG0265@1|root,COG3087@1|root,COG0265@2|Bacteria,COG3087@2|Bacteria,2IXA0@203682|Planctomycetes	203682|Planctomycetes	O	peptidase S1 and S6 chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_6818150_46	1123508.JH636443_gene4856	7.824e-07	61.0	COG0810@1|root,COG0810@2|Bacteria,2J0I0@203682|Planctomycetes	203682|Planctomycetes	M	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
CMS3_k127_6818150_45	1210884.HG799464_gene10594	2.853e-07	62.0	29G09@1|root,302Y2@2|Bacteria,2IZ7F@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_50	530564.Psta_2720	0.0003961	46.0	COG3767@1|root,COG3767@2|Bacteria	2|Bacteria	-	-	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	EF-hand_5
CMS3_k127_6818150_18	530564.Psta_2720	2.015e-61	238.0	COG3767@1|root,COG3767@2|Bacteria	2|Bacteria	-	-	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	EF-hand_5
CMS3_k127_6818150_25	530564.Psta_2695	5.159e-38	166.0	COG1196@1|root,COG1196@2|Bacteria,2J548@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_10	530564.Psta_2696	5.345e-84	309.0	COG2304@1|root,COG2304@2|Bacteria,2IYCE@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS3_k127_6818150_28	1210884.HG799464_gene10590	1.799e-31	143.0	COG1361@1|root,COG1361@2|Bacteria,2IWRS@203682|Planctomycetes	203682|Planctomycetes	M	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS3_k127_6818150_9	344747.PM8797T_29952	3.71e-84	291.0	COG2373@1|root,COG2373@2|Bacteria,2IYJD@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_6818150_48	1123242.JH636438_gene5664	3.04e-06	61.0	COG1520@1|root,COG1520@2|Bacteria,2IZ2Z@203682|Planctomycetes	203682|Planctomycetes	H	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,TPR_6
CMS3_k127_6818150_29	530564.Psta_2697	1.508e-29	137.0	COG1413@1|root,COG1520@1|root,COG1413@2|Bacteria,COG1520@2|Bacteria,2J3VN@203682|Planctomycetes	2|Bacteria	C	HEAT repeats	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	DNA_alkylation,HEAT_2,MFS_1,PQQ_2,cNMP_binding
CMS3_k127_6818150_30	667014.Thein_2154	6.514e-29	129.0	COG0223@1|root,COG0223@2|Bacteria,2GGW2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS3_k127_6818150_42	523850.TON_1276	1.584e-09	71.0	COG0501@1|root,arCOG01334@2157|Archaea,2Y6I8@28890|Euryarchaeota,244MU@183968|Thermococci	183968|Thermococci	O	Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
CMS3_k127_6818150_14	585501.HMPREF6123_1029	1.985e-67	238.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,2PQNA@265975|Oribacterium	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS3_k127_6818150_39	1192034.CAP_2839	2.046e-11	76.0	COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria,2YVW2@29|Myxococcales	28221|Deltaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS3_k127_6818150_13	240302.BN982_01291	1.138e-69	265.0	COG1463@1|root,COG2120@1|root,COG1463@2|Bacteria,COG2120@2|Bacteria,1UYPV@1239|Firmicutes,4HCT3@91061|Bacilli	91061|Bacilli	M	NPCBM-associated, NEW3 domain of alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,PIG-L
CMS3_k127_6818150_23	530564.Psta_3995	2.177e-45	176.0	COG1403@1|root,COG1403@2|Bacteria,2IXXW@203682|Planctomycetes	203682|Planctomycetes	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS3_k127_6818150_47	66692.ABC0749	2.129e-06	60.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,1ZBBP@1386|Bacillus	91061|Bacilli	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_6818150_19	287.DR97_2941	1.226e-60	222.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1YDHQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_6818150_20	497964.CfE428DRAFT_1198	3.832e-60	216.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS3_k127_6818150_12	575540.Isop_3080	2.488e-73	265.0	COG0568@1|root,COG0568@2|Bacteria,2IYCB@203682|Planctomycetes	203682|Planctomycetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS3_k127_6818150_41	471854.Dfer_2810	1.351e-09	63.0	2EGPU@1|root,33AFZ@2|Bacteria,4NXYH@976|Bacteroidetes,47S90@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_36	886293.Sinac_7434	2.038e-13	76.0	2BR4A@1|root,32K29@2|Bacteria,2J1BQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_1	706587.Desti_3768	7.234e-240	763.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,42N15@68525|delta/epsilon subdivisions,2WJ0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS3_k127_6818150_11	1121104.AQXH01000001_gene1714	3.473e-76	264.0	COG3880@1|root,COG3880@2|Bacteria,4PM6C@976|Bacteroidetes,1J107@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS3_k127_6818150_0	886293.Sinac_3666	2.703e-246	802.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2IXNQ@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase, iron-sulfur binding subunit	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
CMS3_k127_6818150_3	344747.PM8797T_11856	3.571e-211	670.0	COG5557@1|root,COG5557@2|Bacteria,2IWYN@203682|Planctomycetes	203682|Planctomycetes	C	Polysulphide reductase	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS3_k127_6818150_24	391625.PPSIR1_01132	9.045e-43	164.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2WT1Y@28221|Deltaproteobacteria,2Z0GX@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS3_k127_6818150_27	518766.Rmar_0225	1.22e-34	146.0	COG2010@1|root,COG2010@2|Bacteria,4PHUX@976|Bacteroidetes,1FJC8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_6818150_8	1192034.CAP_2028	1.773e-99	342.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YY91@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6818150_21	518766.Rmar_0228	1.827e-59	216.0	COG1999@1|root,COG1999@2|Bacteria,4NU1J@976|Bacteroidetes,1FJ7I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS3_k127_6818150_16	1089550.ATTH01000001_gene1168	1.336e-63	241.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,4NFNF@976|Bacteroidetes,1FIVH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CMS3_k127_6818150_2	1267535.KB906767_gene1092	6.827e-225	710.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria,2JIRX@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS3_k127_6818150_17	313628.LNTAR_03419	3.738e-63	226.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS3_k127_6818150_37	1192034.CAP_2034	3.067e-13	76.0	2DR0H@1|root,339NS@2|Bacteria,1R3N7@1224|Proteobacteria,42X1P@68525|delta/epsilon subdivisions,2X8S7@28221|Deltaproteobacteria,2Z3NK@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
CMS3_k127_6818150_4	272134.KB731324_gene5853	1.453e-183	608.0	COG0553@1|root,COG0553@2|Bacteria,1G0S7@1117|Cyanobacteria,1H7YD@1150|Oscillatoriales	1117|Cyanobacteria	L	SNF2 family N-terminal domain	hepA	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,Intein_splicing,LAGLIDADG_3,SNF2_N
CMS3_k127_6818150_49	67281.JNZZ01000035_gene710	8.522e-05	57.0	COG4279@1|root,COG4279@2|Bacteria,2GIYW@201174|Actinobacteria,418XN@629295|Streptomyces griseus group	201174|Actinobacteria	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS3_k127_6819300_2	247490.KSU1_C1209	3.617e-09	63.0	COG0088@1|root,COG0088@2|Bacteria,2IYU2@203682|Planctomycetes	203682|Planctomycetes	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS3_k127_6819300_1	756272.Plabr_2056	1.054e-41	156.0	COG0051@1|root,COG0051@2|Bacteria,2IZQR@203682|Planctomycetes	203682|Planctomycetes	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS3_k127_6819300_0	635013.TherJR_0293	7.39e-121	414.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2600F@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_6851130_0	240016.ABIZ01000001_gene4232	1.649e-165	554.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46TQ1@74201|Verrucomicrobia,2IWNR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_6851130_4	1459636.NTE_02436	1.097e-06	62.0	arCOG02527@1|root,arCOG02527@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NosD
CMS3_k127_6851130_2	1131814.JAFO01000001_gene2573	4.271e-44	163.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
CMS3_k127_6851130_1	1122176.KB903609_gene5148	2.287e-71	271.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS3_k127_6851130_3	671143.DAMO_2768	4.308e-22	104.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_6862840_0	1210884.HG799463_gene9356	6.619e-151	522.0	COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,2J2QP@203682|Planctomycetes	203682|Planctomycetes	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Reg_prop,Y_Y_Y
CMS3_k127_6862840_1	1463841.JOIR01000005_gene5239	4.075e-20	100.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS3_k127_6886002_27	439235.Dalk_5083	4.36e-29	132.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria	1224|Proteobacteria	P	PFAM Phosphate-selective porin O	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS3_k127_6886002_11	929556.Solca_1899	2.025e-122	413.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia	976|Bacteroidetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS3_k127_6886002_42	1125863.JAFN01000001_gene3041	7.066e-05	54.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,FecR,LysM,Peptidase_M15_2,Peptidase_M74
CMS3_k127_6886002_22	575540.Isop_0530	4.768e-41	173.0	COG1212@1|root,COG1212@2|Bacteria,2IYWF@203682|Planctomycetes	203682|Planctomycetes	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS3_k127_6886002_0	886293.Sinac_5091	2.426e-219	701.0	COG0504@1|root,COG0504@2|Bacteria,2IXNE@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS3_k127_6886002_4	945713.IALB_1779	4.123e-155	502.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS3_k127_6886002_39	65497.JODV01000006_gene859	4.303e-09	67.0	COG2981@1|root,COG2981@2|Bacteria,2GJZ4@201174|Actinobacteria,4E0AM@85010|Pseudonocardiales	201174|Actinobacteria	E	protein involved in cysteine biosynthesis	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
CMS3_k127_6886002_2	518766.Rmar_1568	1.105e-177	580.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1FISZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS3_k127_6886002_21	1379698.RBG1_1C00001G1744	1.601e-41	158.0	COG2018@1|root,COG2018@2|Bacteria,2NQXH@2323|unclassified Bacteria	2|Bacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
CMS3_k127_6886002_20	1379698.RBG1_1C00001G1745	2.235e-71	252.0	COG1100@1|root,COG1100@2|Bacteria,2NPDD@2323|unclassified Bacteria	2|Bacteria	K	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
CMS3_k127_6886002_44	243232.MJ_0310	0.0005829	52.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota,23R2D@183939|Methanococci	183939|Methanococci	S	PFAM Roadblock LC7 family protein	-	GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
CMS3_k127_6886002_41	857087.Metme_1325	1.104e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_14,TPR_16,TPR_19,TPR_4,TPR_6,TPR_7,TPR_8
CMS3_k127_6886002_32	316274.Haur_0845	4.566e-17	97.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_6886002_18	1329516.JPST01000003_gene1026	6.022e-93	318.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,27BA9@186824|Thermoactinomycetaceae	91061|Bacilli	E	Aminomethyltransferase folate-binding domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS3_k127_6886002_25	42256.RradSPS_2740	1.012e-36	146.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4CQGM@84995|Rubrobacteria	84995|Rubrobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS3_k127_6886002_29	1198449.ACAM_1473	1.894e-25	119.0	COG0095@1|root,arCOG01939@2157|Archaea,2XQ6U@28889|Crenarchaeota	28889|Crenarchaeota	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS3_k127_6886002_33	861299.J421_3473	5.681e-13	77.0	COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
CMS3_k127_6886002_31	1121441.AUCX01000006_gene870	1.294e-21	108.0	COG2199@1|root,COG3706@2|Bacteria,1QWNG@1224|Proteobacteria,42PE9@68525|delta/epsilon subdivisions,2WJU1@28221|Deltaproteobacteria,2M9H2@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
CMS3_k127_6886002_23	1499967.BAYZ01000158_gene440	2.103e-39	161.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
CMS3_k127_6886002_35	903818.KI912268_gene3082	2.626e-12	75.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS3_k127_6886002_37	457570.Nther_0049	3.832e-10	69.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6886002_10	1304284.L21TH_2295	1.966e-124	419.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS3_k127_6886002_1	1499967.BAYZ01000184_gene4573	1.542e-182	587.0	COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
CMS3_k127_6886002_12	575540.Isop_1165	1.033e-117	391.0	COG1060@1|root,COG1060@2|Bacteria,2IX1I@203682|Planctomycetes	203682|Planctomycetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
CMS3_k127_6886002_15	1167006.UWK_02735	3.257e-108	383.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2MIGE@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
CMS3_k127_6886002_24	32051.SynWH7803_1072	3.677e-39	166.0	COG0697@1|root,COG0697@2|Bacteria,1GHP7@1117|Cyanobacteria,1GYUN@1129|Synechococcus	1117|Cyanobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS3_k127_6886002_28	929556.Solca_1361	8.859e-27	114.0	2CD0I@1|root,30JWK@2|Bacteria,4P4YR@976|Bacteroidetes,1IY9W@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4399
CMS3_k127_6886002_40	575540.Isop_0178	1.262e-07	64.0	COG2755@1|root,COG2755@2|Bacteria,2J1DW@203682|Planctomycetes	203682|Planctomycetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS3_k127_6886002_7	1142394.PSMK_00690	2.278e-141	463.0	COG1696@1|root,COG1696@2|Bacteria,2IX06@203682|Planctomycetes	203682|Planctomycetes	M	membrane protein involved in D-alanine	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
CMS3_k127_6886002_38	278963.ATWD01000001_gene2967	9.213e-10	73.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,3Y49I@57723|Acidobacteria,2JI4I@204432|Acidobacteriia	204432|Acidobacteriia	G	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,VCBS
CMS3_k127_6886002_45	1169152.AXVD01000034_gene195	0.0008628	53.0	COG4658@1|root,COG4658@2|Bacteria,2GNVV@201174|Actinobacteria,4FUEE@85025|Nocardiaceae	201174|Actinobacteria	C	ASPIC and UnbV	-	-	-	ko:K21162	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	UnbV_ASPIC,VCBS
CMS3_k127_6886002_30	1210884.HG799462_gene8087	2.964e-25	124.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CMS3_k127_6886002_3	237368.SCABRO_03724	5.577e-174	563.0	COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
CMS3_k127_6886002_6	622637.KE124770_gene147	5.913e-149	481.0	COG1697@1|root,COG1697@2|Bacteria,1NBFJ@1224|Proteobacteria	1224|Proteobacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
CMS3_k127_6886002_26	28115.HR11_07490	6.41e-35	147.0	COG1649@1|root,COG1649@2|Bacteria,4NHEB@976|Bacteroidetes,2FMZJ@200643|Bacteroidia,22XHM@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS3_k127_6886002_5	521674.Plim_4103	1.823e-152	501.0	COG0677@1|root,COG0677@2|Bacteria,2IXVX@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_6886002_19	237368.SCABRO_00372	1.096e-79	274.0	COG1215@1|root,COG1215@2|Bacteria,2IXXE@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6886002_34	864069.MicloDRAFT_00013520	2.494e-12	76.0	COG1309@1|root,COG1309@2|Bacteria,1RES1@1224|Proteobacteria,2U7NW@28211|Alphaproteobacteria,1JURZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
CMS3_k127_6886002_14	264951.V5HS51	2.091e-108	359.0	COG0320@1|root,KOG2672@2759|Eukaryota,38EBV@33154|Opisthokonta,3NWHD@4751|Fungi,3QMC3@4890|Ascomycota,20CBD@147545|Eurotiomycetes,3S6RA@5042|Eurotiales	4751|Fungi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS3_k127_6886002_16	1192034.CAP_6081	9.724e-105	370.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YV62@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS3_k127_6886002_9	404589.Anae109_1994	8.238e-130	422.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2WK5N@28221|Deltaproteobacteria,2YTX4@29|Myxococcales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	bkdB	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K00167	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_6886002_17	644966.Tmar_1671	4.03e-104	362.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,247Q5@186801|Clostridia	186801|Clostridia	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,CMD,E3_binding
CMS3_k127_6886002_13	1254432.SCE1572_45980	3.416e-111	372.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YY6R@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS3_k127_6886002_8	264462.Bd0778	7.1e-137	452.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2MTJR@213481|Bdellovibrionales,2WIR7@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS3_k127_6886002_36	1267005.KB911255_gene2404	1.259e-10	76.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,3N89M@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	PQQ-like domain	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS3_k127_6886002_43	502025.Hoch_4143	0.0001414	56.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_7,TPR_8
CMS3_k127_6890413_3	42256.RradSPS_3090	7.918e-49	188.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4CTY2@84995|Rubrobacteria	84995|Rubrobacteria	Q	Multicopper oxidase, type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS3_k127_6890413_2	765420.OSCT_0910	7.795e-101	357.0	COG0457@1|root,COG1716@1|root,COG4447@1|root,COG0457@2|Bacteria,COG1716@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CarboxypepD_reg,FHA,Kelch_4,NHL,PA14,Peptidase_C11
CMS3_k127_6890413_7	446462.Amir_2016	0.0002637	55.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS3_k127_6890413_5	639030.JHVA01000001_gene2883	1.915e-05	57.0	COG1651@1|root,COG1651@2|Bacteria,3Y2G9@57723|Acidobacteria,2JIKS@204432|Acidobacteriia	204432|Acidobacteriia	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_6890413_0	595460.RRSWK_00738	2.759e-180	586.0	COG3119@1|root,COG3119@2|Bacteria,2J1TM@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_6890413_1	1242864.D187_004787	5.44e-124	411.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,433XH@68525|delta/epsilon subdivisions,2X2FU@28221|Deltaproteobacteria,2YXR6@29|Myxococcales	28221|Deltaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS3_k127_6890413_6	530564.Psta_0868	4.431e-05	56.0	COG3170@1|root,COG3170@2|Bacteria,2J2WX@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6890413_4	861299.J421_4375	2.248e-42	164.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6890413_8	743718.Isova_0560	0.0005502	47.0	2DGEZ@1|root,2ZVQ5@2|Bacteria,2GYKS@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_689999_0	595460.RRSWK_04882	9.505e-45	177.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS3_k127_689999_1	1123360.thalar_01453	2.456e-11	75.0	29MB0@1|root,3088S@2|Bacteria,1P7BR@1224|Proteobacteria,2UWFB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6903664_2	1121438.JNJA01000005_gene1021	4.381e-07	62.0	COG0500@1|root,COG2226@2|Bacteria,1QXUA@1224|Proteobacteria,42QNQ@68525|delta/epsilon subdivisions,2WMN4@28221|Deltaproteobacteria,2MDRV@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS3_k127_6903664_1	530564.Psta_4046	3.462e-22	104.0	COG1595@1|root,COG1595@2|Bacteria,2IZJE@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6903664_0	1278073.MYSTI_07411	4.867e-62	243.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
CMS3_k127_6904465_1	1121957.ATVL01000008_gene4370	2.883e-27	123.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,4NJ47@976|Bacteroidetes,47TWG@768503|Cytophagia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CMS3_k127_6904465_3	6238.CBG10865	2.098e-05	57.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BAFG@33208|Metazoa,3CV6Z@33213|Bilateria,40DGG@6231|Nematoda,1KZAU@119089|Chromadorea,40U7K@6236|Rhabditida	33208|Metazoa	S	Domain of unknown function (DUF1736)	TMTC4	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_17,TPR_2,TPR_8
CMS3_k127_6904465_0	1500257.JQNM01000002_gene4888	1.743e-121	413.0	COG1032@1|root,COG1032@2|Bacteria,1R9RK@1224|Proteobacteria,2U975@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_6904465_2	1210884.HG799463_gene9801	4.248e-13	80.0	COG2755@1|root,COG3345@1|root,COG5306@1|root,COG2755@2|Bacteria,COG3345@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
CMS3_k127_6909740_2	554065.XP_005844584.1	2.888e-07	62.0	KOG1947@1|root,KOG1947@2759|Eukaryota	2759|Eukaryota	B	F-box LRR-repeat protein	-	-	-	ko:K10268	-	-	-	-	ko00000,ko04121	-	-	-	LRR_6
CMS3_k127_6909740_0	391625.PPSIR1_28388	1.1e-77	267.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
CMS3_k127_6909740_1	715226.ABI_30530	2.388e-48	177.0	COG2133@1|root,COG2133@2|Bacteria,1RHI4@1224|Proteobacteria,2UF03@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS3_k127_6913553_4	1396141.BATP01000057_gene2939	1.087e-92	316.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	cqsA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K10915	ko00260,ko00780,ko01100,ko02024,ko05111,map00260,map00780,map01100,map02024,map05111	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding
CMS3_k127_6913553_5	1321786.HMPREF1992_01699	1.632e-80	295.0	COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4H3W2@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CMS3_k127_6913553_2	504472.Slin_6349	1.087e-125	434.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,47K7T@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	ykfB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20,5.1.1.3	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	-	R00260,R10938	RC00302,RC03309	ko00000,ko00001,ko01000,ko01011	-	-	-	MR_MLE_C,MR_MLE_N
CMS3_k127_6913553_8	215803.DB30_5360	2.423e-24	111.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6913553_9	1082931.KKY_2464	1.917e-20	102.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,2UDT6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6913553_10	1487953.JMKF01000059_gene4896	6.545e-16	91.0	COG0265@1|root,COG0265@2|Bacteria,1G17C@1117|Cyanobacteria,1H723@1150|Oscillatoriales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	hhoA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_6913553_12	867845.KI911784_gene1883	3.106e-09	70.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
CMS3_k127_6913553_7	352165.HMPREF7215_0448	1.092e-52	191.0	COG3012@1|root,COG3012@2|Bacteria,3TC58@508458|Synergistetes	508458|Synergistetes	U	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
CMS3_k127_6913553_1	886293.Sinac_5684	4.247e-143	469.0	COG4102@1|root,COG4102@2|Bacteria,2IWYX@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_6913553_3	886293.Sinac_5683	1.845e-104	380.0	COG3064@1|root,COG3064@2|Bacteria,2IWVN@203682|Planctomycetes	203682|Planctomycetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PPC
CMS3_k127_6913553_0	530564.Psta_2092	1.581e-214	724.0	COG5492@1|root,COG5492@2|Bacteria,2IXP9@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
CMS3_k127_6913553_6	314230.DSM3645_21272	6.061e-71	265.0	COG2319@1|root,COG2319@2|Bacteria,2IXJX@203682|Planctomycetes	203682|Planctomycetes	C	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
CMS3_k127_6913553_11	105420.BBPO01000178_gene6337	2.436e-09	67.0	COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,2NMP3@228398|Streptacidiphilus	201174|Actinobacteria	L	HTH-like domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
CMS3_k127_6926621_3	1123242.JH636434_gene5244	2.019e-82	299.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6926621_0	83332.Rv3109	1.228e-110	376.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,232UP@1762|Mycobacteriaceae	201174|Actinobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CMS3_k127_6926621_1	391625.PPSIR1_40710	2.967e-96	340.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2Z21X@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS3_k127_6926621_2	502025.Hoch_5036	3.98e-83	284.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42MFD@68525|delta/epsilon subdivisions,2WJCZ@28221|Deltaproteobacteria,2YXV3@29|Myxococcales	28221|Deltaproteobacteria	K	PFAM Silent information regulator protein Sir2	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS3_k127_6926621_4	1121434.AULY01000006_gene393	9.906e-20	93.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2MCMH@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS3_k127_6926621_5	1236976.JCM16418_2311	9.027e-10	68.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,26QIY@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_6954587_3	472759.Nhal_3587	9.264e-42	166.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria,1X0FH@135613|Chromatiales	135613|Chromatiales	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS3_k127_6954587_6	1403819.BATR01000132_gene4688	6.607e-32	145.0	2BMSD@1|root,32GBT@2|Bacteria,46VIR@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6954587_0	153948.NAL212_0248	0.0	1095.0	COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,1MWMG@1224|Proteobacteria,2VHWC@28216|Betaproteobacteria,373ZI@32003|Nitrosomonadales	28216|Betaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559
CMS3_k127_6954587_5	215803.DB30_6589	7.51e-40	160.0	COG2339@1|root,COG2339@2|Bacteria,1PCW8@1224|Proteobacteria,4343U@68525|delta/epsilon subdivisions,2X52Q@28221|Deltaproteobacteria,2Z013@29|Myxococcales	28221|Deltaproteobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
CMS3_k127_6954587_10	6500.XP_005100813.1	6.051e-13	83.0	2BW0M@1|root,2QTDG@2759|Eukaryota,38G52@33154|Opisthokonta,3BGNE@33208|Metazoa,3CVZ1@33213|Bilateria	33208|Metazoa	S	Von Willebrand factor A	VWA3A	-	-	-	-	-	-	-	-	-	-	-	VWA_3
CMS3_k127_6954587_11	1906.SFRA_31770	4.819e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6954587_4	1123508.JH636449_gene7349	2.593e-41	173.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_6954587_7	204669.Acid345_0263	2.063e-23	116.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS3_k127_6954587_8	1111730.ATTM01000007_gene2449	1.365e-21	103.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,2NSK3@237|Flavobacterium	976|Bacteroidetes	G	hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
CMS3_k127_6954587_1	1396141.BATP01000023_gene581	1.745e-172	554.0	COG3119@1|root,COG3119@2|Bacteria,46ZM3@74201|Verrucomicrobia,2IVPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS3_k127_6954587_2	497964.CfE428DRAFT_5721	1.628e-160	544.0	COG2133@1|root,COG2133@2|Bacteria,46UAQ@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Laminin_G_3
CMS3_k127_6954587_9	1123392.AQWL01000008_gene1237	2.548e-14	88.0	COG3299@1|root,COG3299@2|Bacteria,1P3E0@1224|Proteobacteria,2VKDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,PA14
CMS3_k127_6959986_8	526222.Desal_0399	0.0009311	51.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2M98X@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS3_k127_6959986_3	344747.PM8797T_29952	1.822e-75	270.0	COG2373@1|root,COG2373@2|Bacteria,2IYJD@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
CMS3_k127_6959986_6	1340493.JNIF01000003_gene2039	5.447e-46	183.0	2E9F7@1|root,333NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6959986_4	360910.BAV2975	2e-74	258.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS3_k127_6959986_1	351348.Maqu_1828	4.799e-85	299.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,1S20R@1236|Gammaproteobacteria,4671B@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Uracil-DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	UDG
CMS3_k127_6959986_0	314230.DSM3645_11382	1.233e-219	710.0	COG3119@1|root,COG3119@2|Bacteria,2IX2H@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.14	ko:K01137	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_6959986_7	112098.XP_008618512.1	1.323e-23	117.0	COG0457@1|root,KOG1124@2759|Eukaryota	2759|Eukaryota	O	cellular component assembly	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_16,TPR_8
CMS3_k127_6959986_5	864702.OsccyDRAFT_4934	3.237e-62	228.0	COG1216@1|root,COG1216@2|Bacteria,1G4RU@1117|Cyanobacteria,1HH4K@1150|Oscillatoriales	1117|Cyanobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_6959986_2	469383.Cwoe_1050	5.69e-80	282.0	COG0491@1|root,COG0491@2|Bacteria,2GJ7I@201174|Actinobacteria,4CQ3N@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_6974277_11	1123368.AUIS01000001_gene1867	1.014e-50	186.0	COG3621@1|root,COG3621@2|Bacteria,1RDY7@1224|Proteobacteria,1RSC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_6974277_8	1122179.KB890447_gene342	3.968e-89	323.0	COG2706@1|root,COG2706@2|Bacteria,4PP03@976|Bacteroidetes	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS3_k127_6974277_6	595460.RRSWK_03108	5.345e-124	427.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_6974277_14	937777.Deipe_2514	6.9e-25	121.0	COG3055@1|root,COG3055@2|Bacteria,1WNDD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929
CMS3_k127_6974277_19	227882.SAV_5287	5.805e-07	63.0	COG5555@1|root,COG5555@2|Bacteria,2GKZ9@201174|Actinobacteria	201174|Actinobacteria	N	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CMS3_k127_6974277_21	794903.OPIT5_11255	5.617e-06	53.0	COG0012@1|root,COG0012@2|Bacteria,46UY8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6974277_10	756272.Plabr_0510	1.4e-65	232.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_6974277_12	1123242.JH636436_gene131	1.545e-40	164.0	COG0750@1|root,COG0750@2|Bacteria,2IXR8@203682|Planctomycetes	203682|Planctomycetes	MO	MucD-putative a secreted serine proteinase	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
CMS3_k127_6974277_13	530564.Psta_1650	2.543e-31	142.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_6974277_0	886293.Sinac_2812	0.0	1039.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX57@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	Cytochrom_C,ThuA
CMS3_k127_6974277_16	215803.DB30_2422	2.028e-10	75.0	COG0750@1|root,COG4932@1|root,COG0750@2|Bacteria,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6974277_1	1396141.BATP01000028_gene2302	2.114e-307	977.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46UFX@74201|Verrucomicrobia,2ITPA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_6974277_18	292459.STH2212	1.232e-07	64.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CarboxypepD_reg,HemolysinCabind
CMS3_k127_6974277_4	344747.PM8797T_06060	3.752e-164	534.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_6974277_22	79684.XP_005348803.1	2.018e-05	57.0	COG2304@1|root,2QPS2@2759|Eukaryota,38C6V@33154|Opisthokonta,3BE0X@33208|Metazoa,3CW49@33213|Bilateria,4803N@7711|Chordata,48YJP@7742|Vertebrata,3JF6U@40674|Mammalia,35NE9@314146|Euarchontoglires,4Q2QS@9989|Rodentia	33208|Metazoa	S	inhibitor, heavy chain	ITIH4	GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503	-	-	-	-	-	-	-	-	-	-	ITI_HC_C,VIT,VWA
CMS3_k127_6974277_7	471853.Bcav_2303	1.941e-101	357.0	COG1082@1|root,COG1082@2|Bacteria,2I94Z@201174|Actinobacteria	201174|Actinobacteria	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS3_k127_6974277_15	756272.Plabr_4234	4.388e-15	85.0	COG4692@1|root,COG4692@2|Bacteria,2IX4M@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
CMS3_k127_6974277_23	344747.PM8797T_24886	4.24e-05	57.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	CAP,HemolysinCabind,Peptidase_M10_C,VCBS
CMS3_k127_6974277_17	378806.STAUR_4755	6.279e-08	66.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria,2YYWS@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_6974277_20	290397.Adeh_2145	9.901e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,1PER9@1224|Proteobacteria,434KX@68525|delta/epsilon subdivisions,2WYYB@28221|Deltaproteobacteria,2Z0X1@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_6974277_2	886293.Sinac_2770	1.915e-180	589.0	COG0526@1|root,COG0526@2|Bacteria,2IYKJ@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CMS3_k127_6974277_9	1123242.JH636436_gene716	8.563e-81	290.0	COG1012@1|root,COG1012@2|Bacteria,2J22K@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS3_k127_6974277_5	317619.ANKN01000189_gene3686	1.626e-142	471.0	2EB6E@1|root,33574@2|Bacteria,1GD8U@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6974277_24	404589.Anae109_0911	9.68e-05	56.0	COG0793@1|root,COG3485@1|root,COG0793@2|Bacteria,COG3485@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_6974277_3	243090.RB5378	1.002e-168	544.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS3_k127_701696_5	318996.AXAZ01000015_gene3633	3e-78	287.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_8,TolB_N
CMS3_k127_701696_12	1396418.BATQ01000184_gene2606	1.109e-31	137.0	COG2863@1|root,COG2863@2|Bacteria,46WZQ@74201|Verrucomicrobia,2IW1M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS3_k127_701696_14	765698.Mesci_2898	8.329e-07	61.0	COG3391@1|root,COG3391@2|Bacteria,1N25Z@1224|Proteobacteria,2TUAK@28211|Alphaproteobacteria,43J82@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	PQQ-like domain	MA20_01585	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2,PQQ_2
CMS3_k127_701696_6	555088.DealDRAFT_0321	3.868e-73	259.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,42KC0@68298|Syntrophomonadaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS3_k127_701696_13	1128427.KB904821_gene763	1.787e-16	87.0	COG0789@1|root,COG0789@2|Bacteria,1G6K7@1117|Cyanobacteria,1HHG3@1150|Oscillatoriales	1117|Cyanobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS3_k127_701696_1	521674.Plim_1525	2.626e-212	686.0	COG4102@1|root,COG4102@2|Bacteria,2IXRZ@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_701696_0	1396141.BATP01000057_gene2941	9.162e-304	965.0	COG2411@1|root,COG2411@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ASCH,PSCyt1,PSCyt2,PSD1
CMS3_k127_701696_4	1185876.BN8_06219	4.751e-115	391.0	COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47MBT@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS3_k127_701696_7	1121405.dsmv_1616	3.538e-64	228.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,437EH@68525|delta/epsilon subdivisions,2XA2G@28221|Deltaproteobacteria,2MNAI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_701696_11	1265505.ATUG01000001_gene4610	6.009e-41	160.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,42XEQ@68525|delta/epsilon subdivisions,2WTD9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
CMS3_k127_701696_10	1123277.KB893243_gene326	1.231e-44	173.0	COG3023@1|root,COG3023@2|Bacteria,4NMIV@976|Bacteroidetes,47PNG@768503|Cytophagia	976|Bacteroidetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
CMS3_k127_701696_9	1403819.BATR01000131_gene4677	1.003e-55	207.0	28IP5@1|root,2Z8P7@2|Bacteria	2|Bacteria	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS3_k127_701696_2	382464.ABSI01000007_gene4160	4.056e-150	499.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46TWP@74201|Verrucomicrobia,2ITWT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS3_k127_701696_3	1122939.ATUD01000001_gene577	1.042e-124	437.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_701696_8	1123242.JH636436_gene255	4.28e-64	230.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS3_k127_7029269_7	388051.AUFE01000021_gene89	1.773e-14	77.0	COG5649@1|root,COG5649@2|Bacteria,1RDDG@1224|Proteobacteria,2W0C7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS3_k127_7029269_2	1429916.X566_18740	9.705e-58	219.0	COG3832@1|root,COG3832@2|Bacteria,1RD0P@1224|Proteobacteria,2U79U@28211|Alphaproteobacteria,3K0I0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_7029269_3	1210884.HG799471_gene14625	8.411e-50	192.0	COG3832@1|root,COG3832@2|Bacteria,2J16I@203682|Planctomycetes	203682|Planctomycetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS3_k127_7029269_5	1040986.ATYO01000001_gene1777	3.387e-32	128.0	COG0640@1|root,COG0640@2|Bacteria,1N10H@1224|Proteobacteria,2UBRH@28211|Alphaproteobacteria,43KD8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_7029269_0	521674.Plim_1437	2.247e-157	508.0	COG3345@1|root,COG3345@2|Bacteria,2IZER@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS3_k127_7029269_8	1095769.CAHF01000005_gene1585	0.0006186	52.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2VX5D@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
CMS3_k127_7029269_6	1278073.MYSTI_03939	4.244e-15	90.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1Q2N3@1224|Proteobacteria,4388W@68525|delta/epsilon subdivisions,2XA2N@28221|Deltaproteobacteria,2YXAB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS3_k127_7029269_1	243231.GSU1431	1.74e-101	359.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,42NEZ@68525|delta/epsilon subdivisions,2WJ5R@28221|Deltaproteobacteria,43U4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
CMS3_k127_7029269_4	296587.XP_002500081.1	1.719e-48	187.0	COG0480@1|root,KOG0465@2759|Eukaryota,37K55@33090|Viridiplantae,34GS5@3041|Chlorophyta	3041|Chlorophyta	J	catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_7041610_2	1136417.AZWE01000027_gene2819	4.817e-22	104.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4D95T@85008|Micromonosporales	201174|Actinobacteria	GL	Reverse transcriptase-like	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
CMS3_k127_7041610_1	330214.NIDE1891	4.295e-35	154.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Cytochrom_C,DUF1080,DUF4132,Pkinase
CMS3_k127_7041610_0	429009.Adeg_0526	1.299e-107	357.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS3_k127_7074521_3	313606.M23134_04260	1.42e-80	283.0	COG4826@1|root,COG4826@2|Bacteria,4NG1G@976|Bacteroidetes,47N0P@768503|Cytophagia	976|Bacteroidetes	O	proteinase inhibitor I4 serpin	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
CMS3_k127_7074521_2	1303518.CCALI_00760	2.817e-196	640.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,COesterase,Esterase,Peptidase_S9
CMS3_k127_7074521_4	1335760.ASTG01000008_gene972	3.781e-07	61.0	COG3637@1|root,COG3637@2|Bacteria,1PW82@1224|Proteobacteria,2U8GW@28211|Alphaproteobacteria,2K6DC@204457|Sphingomonadales	204457|Sphingomonadales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7074521_1	762982.HMPREF9442_01617	2.661e-197	642.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,2FM1I@200643|Bacteroidia	976|Bacteroidetes	S	cog cog3533	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS3_k127_7074521_0	1288963.ADIS_0491	1.511e-258	821.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS3_k127_7082459_10	1157490.EL26_00240	5.845e-92	316.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,2784E@186823|Alicyclobacillaceae	91061|Bacilli	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	iYO844.BSU29710	Hist_deacetyl
CMS3_k127_7082459_29	1120705.FG95_00213	1.144e-28	132.0	COG0500@1|root,COG2226@2|Bacteria,1NHFP@1224|Proteobacteria	1224|Proteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_7082459_34	404589.Anae109_4442	1.024e-18	99.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
CMS3_k127_7082459_13	1123508.JH636449_gene7349	5.445e-65	251.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_7082459_8	631454.N177_2463	5.015e-102	340.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,1JNJU@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS3_k127_7082459_41	1038860.AXAP01000003_gene8176	2.723e-05	54.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,3JT5X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7082459_31	765420.OSCT_1732	9.6e-26	122.0	COG1063@1|root,COG1063@2|Bacteria,2G5WZ@200795|Chloroflexi,376KB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_7082459_23	706587.Desti_3917	1.368e-37	158.0	COG1597@1|root,COG1597@2|Bacteria,1RIPU@1224|Proteobacteria,43DQE@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS3_k127_7082459_27	251221.35213692	3.602e-33	139.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose reductase	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS3_k127_7082459_16	1342302.JASC01000002_gene73	7.132e-57	213.0	COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,2U7CA@28211|Alphaproteobacteria,3ZUVZ@60136|Sulfitobacter	28211|Alphaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7082459_20	243233.MCA2174	2.256e-39	165.0	COG0803@1|root,COG0803@2|Bacteria,1RAQU@1224|Proteobacteria	1224|Proteobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS3_k127_7082459_7	1415779.JOMH01000001_gene76	1.067e-110	370.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS3_k127_7082459_15	886293.Sinac_6796	1.826e-57	220.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CMS3_k127_7082459_25	344747.PM8797T_24521	1.292e-35	155.0	2ECB1@1|root,3369C@2|Bacteria,2J4U8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7082459_12	243233.MCA2173	4.325e-67	257.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	MacB_PCD
CMS3_k127_7082459_30	685778.AORL01000017_gene16	7.539e-28	131.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VF7J@28211|Alphaproteobacteria,2KDXG@204457|Sphingomonadales	204457|Sphingomonadales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,Pkinase
CMS3_k127_7082459_40	935863.AWZR01000006_gene1234	2.329e-06	61.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,1X4CK@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7082459_22	1123508.JH636449_gene7349	6.606e-38	162.0	COG0515@1|root,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS3_k127_7082459_21	886293.Sinac_4434	1.896e-38	159.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
CMS3_k127_7082459_43	316274.Haur_0845	0.0001789	55.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_7082459_19	562970.Btus_0866	4.435e-46	172.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS3_k127_7082459_32	497964.CfE428DRAFT_0966	5.901e-24	119.0	COG1262@1|root,COG1262@2|Bacteria,46SPX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS3_k127_7082459_17	515622.bpr_I1962	4.117e-53	201.0	COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,4BXGW@830|Butyrivibrio	186801|Clostridia	T	HDOD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Hpt,Response_reg
CMS3_k127_7082459_14	585503.HMPREF7545_0521	5.188e-59	219.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4H2QQ@909932|Negativicutes	909932|Negativicutes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS3_k127_7082459_1	589865.DaAHT2_2323	4.443e-184	600.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,42MXK@68525|delta/epsilon subdivisions,2WKEJ@28221|Deltaproteobacteria,2MI70@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
CMS3_k127_7082459_9	886293.Sinac_1472	2.25e-95	345.0	COG1131@1|root,COG1131@2|Bacteria,2IY2I@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_7082459_11	1123508.JH636441_gene3665	3.483e-68	256.0	COG0842@1|root,COG0842@2|Bacteria,2IY6D@203682|Planctomycetes	203682|Planctomycetes	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
CMS3_k127_7082459_33	290399.Arth_0707	6.967e-21	106.0	29QD5@1|root,30BCD@2|Bacteria,2IG1I@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF695
CMS3_k127_7082459_24	398767.Glov_3258	3.338e-36	155.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CMS3_k127_7082459_0	485913.Krac_12092	2.123e-232	737.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS3_k127_7082459_2	1121957.ATVL01000008_gene4046	6.464e-149	486.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS3_k127_7082459_35	794903.OPIT5_14435	1.591e-15	92.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS3_k127_7082459_28	760192.Halhy_2349	1.505e-30	123.0	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CMS3_k127_7082459_37	157072.XP_008864831.1	4.638e-10	67.0	2ERBS@1|root,2SU60@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7082459_36	1167006.UWK_01111	1.579e-14	86.0	COG2974@1|root,COG2974@2|Bacteria,1RCUH@1224|Proteobacteria,42QVW@68525|delta/epsilon subdivisions,2WN5B@28221|Deltaproteobacteria,2MJPM@213118|Desulfobacterales	28221|Deltaproteobacteria	L	May be involved in recombination	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
CMS3_k127_7082459_38	589865.DaAHT2_1960	2.104e-09	68.0	COG2974@1|root,COG2974@2|Bacteria,1N4GC@1224|Proteobacteria,42RPT@68525|delta/epsilon subdivisions,2WQUM@28221|Deltaproteobacteria,2MJSD@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Putative exonuclease, RdgC	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
CMS3_k127_7082459_39	290315.Clim_0014	5.684e-09	68.0	COG0760@1|root,COG0760@2|Bacteria,1FDC8@1090|Chlorobi	1090|Chlorobi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N,SurA_N_3
CMS3_k127_7082459_42	1219084.AP014508_gene653	0.0001	54.0	COG1073@1|root,COG1073@2|Bacteria,2GC7C@200918|Thermotogae	200918|Thermotogae	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS3_k127_7082459_4	511062.GU3_11625	2.767e-135	468.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1Y55Q@135624|Aeromonadales	135624|Aeromonadales	I	Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS3_k127_7082459_5	1307761.L21SP2_2376	3.904e-128	422.0	COG0183@1|root,COG0183@2|Bacteria,2JBB9@203691|Spirochaetes	203691|Spirochaetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS3_k127_7082459_3	1379698.RBG1_1C00001G0785	1.281e-141	465.0	COG1541@1|root,COG1541@2|Bacteria,2NREC@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS3_k127_7082459_26	1163617.SCD_n01764	1.01e-33	147.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS3_k127_7082459_18	1303518.CCALI_01588	8.148e-53	210.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
CMS3_k127_7082459_6	1192034.CAP_3531	1.956e-124	414.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,42MN7@68525|delta/epsilon subdivisions,2WIVK@28221|Deltaproteobacteria,2YYIN@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
CMS3_k127_7101019_8	864051.BurJ1DRAFT_1465	5.776e-86	291.0	COG1524@1|root,COG1524@2|Bacteria,1P235@1224|Proteobacteria,2VMG4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS3_k127_7101019_3	344747.PM8797T_03484	6.886e-139	462.0	COG0500@1|root,COG2226@2|Bacteria,2IYB6@203682|Planctomycetes	203682|Planctomycetes	Q	Methylase involved in ubiquinone menaquinone	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CMS3_k127_7101019_9	870187.Thini_0176	2.913e-84	294.0	COG0628@1|root,COG0628@2|Bacteria,1PTH3@1224|Proteobacteria	1224|Proteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS3_k127_7101019_5	1123277.KB893177_gene3604	4.703e-127	424.0	COG1073@1|root,COG1073@2|Bacteria,4NI6C@976|Bacteroidetes,47N3Z@768503|Cytophagia	976|Bacteroidetes	S	Acetyl xylan esterase	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS3_k127_7101019_11	344747.PM8797T_27532	1.647e-49	186.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_7101019_2	1210884.HG799473_gene15023	2.504e-140	474.0	COG0823@1|root,COG1506@1|root,COG2866@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,COG2866@2|Bacteria,2J1EY@203682|Planctomycetes	203682|Planctomycetes	E	Zinc carboxypeptidase	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_M14,Peptidase_S9
CMS3_k127_7101019_12	1122179.KB890434_gene874	1.649e-42	175.0	COG4733@1|root,COG5276@1|root,COG4733@2|Bacteria,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1IYS6@117747|Sphingobacteriia	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
CMS3_k127_7101019_10	237368.SCABRO_01077	2.332e-58	229.0	COG1032@1|root,COG1032@2|Bacteria,2J1TE@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS3_k127_7101019_13	1183438.GKIL_2249	1.053e-29	126.0	COG3555@1|root,COG3555@2|Bacteria,1G0W9@1117|Cyanobacteria	1117|Cyanobacteria	O	Aspartyl asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
CMS3_k127_7101019_4	926550.CLDAP_25890	3.125e-132	464.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi	200795|Chloroflexi	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS3_k127_7101019_0	344747.PM8797T_10374	3.054e-252	802.0	COG0531@1|root,COG0531@2|Bacteria,2J1TF@203682|Planctomycetes	203682|Planctomycetes	E	Solute carrier family 12	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,SLC12
CMS3_k127_7101019_7	266835.14026751	4.947e-89	305.0	COG1028@1|root,COG1028@2|Bacteria,1MXTP@1224|Proteobacteria,2TQST@28211|Alphaproteobacteria,43N4Q@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.175	ko:K22185	ko00040,map00040	-	R01429	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS3_k127_7101019_6	1089552.KI911559_gene1070	9.155e-93	324.0	COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2TUTF@28211|Alphaproteobacteria,2JSIT@204441|Rhodospirillales	204441|Rhodospirillales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
CMS3_k127_7101019_1	1469245.JFBG01000053_gene2072	6e-240	753.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1WW0Q@135613|Chromatiales	1236|Gammaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS3_k127_7102022_2	1396418.BATQ01000117_gene4568	5.157e-176	562.0	COG0738@1|root,COG0738@2|Bacteria,46U7F@74201|Verrucomicrobia,2IUMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_7102022_0	344747.PM8797T_06527	0.0	1797.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXGT@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
CMS3_k127_7102022_1	1120966.AUBU01000003_gene1282	8.369e-178	586.0	COG0673@1|root,COG0673@2|Bacteria,4NEJM@976|Bacteroidetes,47NS9@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_7102022_3	545276.KB898732_gene2389	1.38e-106	379.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1WWKU@135613|Chromatiales	135613|Chromatiales	M	Sugar transferase, PEP-CTERM EpsH1 system associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS3_k127_7102022_6	1295642.H839_00370	1.203e-28	126.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1WETT@129337|Geobacillus	91061|Bacilli	K	binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7102022_7	1122604.JONR01000026_gene3023	2.558e-06	56.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,1SFJZ@1236|Gammaproteobacteria,1XANH@135614|Xanthomonadales	135614|Xanthomonadales	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS3_k127_7102022_4	1265503.KB905175_gene3948	2.513e-100	349.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multi-copper	cueO	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0006950,GO:0008150,GO:0008152,GO:0009636,GO:0010035,GO:0010038,GO:0010273,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0016724,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0055114,GO:0061687,GO:0097501,GO:0098754,GO:1990169	1.3.3.5	ko:K08100,ko:K14588	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_0130,iECSP_1301.ECSP_0124,iSbBS512_1146.SbBS512_E0116	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,TAT_signal
CMS3_k127_7102022_5	391625.PPSIR1_31633	2.938e-79	272.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
CMS3_k127_7110962_0	595460.RRSWK_02101	1.913e-57	217.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IWUD@203682|Planctomycetes	203682|Planctomycetes	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,WD40
CMS3_k127_7110962_2	749414.SBI_04632	3.231e-08	64.0	COG1595@1|root,COG1595@2|Bacteria,2GNBE@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7110962_1	1279009.ADICEAN_01425	5.23e-23	107.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,47P7M@768503|Cytophagia	976|Bacteroidetes	L	pfam nudix	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_7110962_3	596151.DesfrDRAFT_1819	3.03e-06	60.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2M82M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS3_k127_7111641_0	1254432.SCE1572_22375	5.774e-39	168.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7137227_1	313628.LNTAR_18530	1.776e-126	425.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	ko:K06610,ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1,2.A.1.1.27	-	-	MFS_1
CMS3_k127_7137227_0	344747.PM8797T_03995	2.59e-264	828.0	COG0008@1|root,COG0008@2|Bacteria,2IYSE@203682|Planctomycetes	203682|Planctomycetes	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS3_k127_7137227_2	1121937.AUHJ01000001_gene644	2.993e-94	326.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,1RNNU@1236|Gammaproteobacteria,464T0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese,Rhodanese_C
CMS3_k127_7137227_6	682795.AciX8_0041	1.541e-40	156.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS3_k127_7137227_5	448385.sce0971	2.261e-42	175.0	29XG3@1|root,30J6J@2|Bacteria,1QSSU@1224|Proteobacteria,4355H@68525|delta/epsilon subdivisions,2X95V@28221|Deltaproteobacteria,2Z23G@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7137227_3	1254432.SCE1572_07125	5.999e-79	289.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,42KZ6@68525|delta/epsilon subdivisions,2WVSN@28221|Deltaproteobacteria,2Z1YP@29|Myxococcales	28221|Deltaproteobacteria	F	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CMS3_k127_7137227_7	313628.LNTAR_18525	3.939e-18	100.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	3.1.3.1,3.1.3.5,3.6.1.45	ko:K01077,ko:K11751	ko00230,ko00240,ko00730,ko00760,ko00790,ko01100,ko01110,ko02020,map00230,map00240,map00730,map00760,map00790,map01100,map01110,map02020	M00126	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02135,R02323,R02719,R03346,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Big_2,Cadherin-like,Cu_amine_oxidN1,DUF4430,FIVAR,Flg_new,Prenyltrans,SLH
CMS3_k127_7137227_4	886293.Sinac_6489	1.029e-73	284.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS3_k127_7137227_8	706587.Desti_5103	1.502e-11	74.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7150447_5	530564.Psta_2150	1.273e-80	286.0	COG1520@1|root,COG1520@2|Bacteria,2IYV0@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_7150447_6	1232437.KL662018_gene599	1.762e-63	230.0	COG0596@1|root,COG0596@2|Bacteria,1NEZY@1224|Proteobacteria,42WGF@68525|delta/epsilon subdivisions,2WSB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7150447_2	1210884.HG799469_gene14163	1.092e-121	413.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_7150447_7	521674.Plim_1358	2.244e-25	123.0	2E13H@1|root,32WIX@2|Bacteria,2J0HQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7150447_3	595460.RRSWK_03108	1.258e-119	410.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_7150447_1	314230.DSM3645_20627	1.304e-130	434.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_7150447_0	497964.CfE428DRAFT_4660	1.128e-142	465.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_7150447_4	518766.Rmar_1973	2.933e-98	329.0	COG1878@1|root,COG1878@2|Bacteria,4PIWM@976|Bacteroidetes,1FJPB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative cyclase	-	GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
CMS3_k127_7196586_0	323261.Noc_2047	1.803e-221	725.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1WW8N@135613|Chromatiales	135613|Chromatiales	I	Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_7196586_1	1163617.SCD_n00025	6.672e-189	603.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria	1224|Proteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_7196586_2	1286093.C266_01340	1.318e-97	350.0	COG0668@1|root,COG0668@2|Bacteria,1MVX9@1224|Proteobacteria,2VHK5@28216|Betaproteobacteria,1K4WG@119060|Burkholderiaceae	28216|Betaproteobacteria	M	mechanosensitive ion channel	mscM	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
CMS3_k127_7259984_15	1089550.ATTH01000001_gene1987	1.549e-08	61.0	COG2866@1|root,COG2931@1|root,COG3291@1|root,COG2866@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,4NKIR@976|Bacteroidetes	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
CMS3_k127_7259984_13	1449126.JQKL01000036_gene1950	6.949e-27	128.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,HemolysinCabind
CMS3_k127_7259984_11	251221.35214825	3.952e-50	199.0	COG2755@1|root,COG3055@1|root,COG2755@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	DUF1929,F5_F8_type_C,Flg_new,Kelch_6,Lipase_GDSL_2
CMS3_k127_7259984_1	1183438.GKIL_1242	6.921e-168	541.0	COG0362@1|root,COG0362@2|Bacteria,1G01J@1117|Cyanobacteria	1117|Cyanobacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS3_k127_7259984_4	467661.RKLH11_3573	7.952e-128	420.0	COG5441@1|root,COG5441@2|Bacteria,1MX45@1224|Proteobacteria,2TUHA@28211|Alphaproteobacteria,3ZGA3@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,UPF0261
CMS3_k127_7259984_5	314256.OG2516_16479	2.496e-119	390.0	COG5564@1|root,COG5564@2|Bacteria,1MXTY@1224|Proteobacteria,2TSJ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	TIM-barrel enzyme, possibly a dioxygenase	MA20_13935	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
CMS3_k127_7259984_7	756272.Plabr_3223	1.173e-98	326.0	COG0693@1|root,COG0693@2|Bacteria,2IY0P@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease amidase	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS3_k127_7259984_10	240016.ABIZ01000001_gene2690	1.833e-71	252.0	COG2267@1|root,COG2267@2|Bacteria,46Z3E@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS3_k127_7259984_9	1396418.BATQ01000106_gene5347	1.001e-78	290.0	COG0235@1|root,COG0235@2|Bacteria,46U10@74201|Verrucomicrobia,2IUBM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS3_k127_7259984_0	1396418.BATQ01000106_gene5346	1.072e-209	668.0	COG1069@1|root,COG1069@2|Bacteria,46UI3@74201|Verrucomicrobia,2ITGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
CMS3_k127_7259984_14	929562.Emtol_2904	2.848e-13	78.0	2EUTM@1|root,33N96@2|Bacteria,4P5GD@976|Bacteroidetes,47VWS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7259984_17	1040987.AZUY01000047_gene4463	3.918e-05	55.0	COG1618@1|root,COG1618@2|Bacteria,1QYYY@1224|Proteobacteria,2TY26@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	nucleotide phosphatase activity, acting on free nucleotides	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
CMS3_k127_7259984_16	1173022.Cri9333_4875	2.727e-06	60.0	COG1216@1|root,COG1216@2|Bacteria,1G2JY@1117|Cyanobacteria,1HE10@1150|Oscillatoriales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS3_k127_7259984_12	861299.J421_6341	1.021e-48	177.0	COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_7259984_8	861299.J421_6340	1.768e-98	329.0	COG1028@1|root,COG1028@2|Bacteria,1ZTIT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_7259984_3	861299.J421_1321	2.152e-132	428.0	COG0115@1|root,COG0115@2|Bacteria,1ZTH5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS3_k127_7259984_6	56110.Oscil6304_1708	1.31e-118	394.0	COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7259984_2	525897.Dbac_0079	1.843e-167	535.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_738475_0	1049564.TevJSym_aa01890	1.266e-150	490.0	COG0699@1|root,COG0699@2|Bacteria,1MV59@1224|Proteobacteria,1RYGW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CMS3_k127_7431256_1	313628.LNTAR_17728	1.274e-161	522.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4976,Sulfatase
CMS3_k127_7431256_8	1380356.JNIK01000006_gene1524	3.88e-13	79.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4ESRE@85013|Frankiales	201174|Actinobacteria	T	FHA domain containing protein	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
CMS3_k127_7431256_7	1210046.B277_13909	7.519e-16	91.0	COG3173@1|root,COG3173@2|Bacteria,2I5QH@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS3_k127_7431256_2	78245.Xaut_0825	7.752e-78	287.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
CMS3_k127_7431256_5	1117108.PAALTS15_10359	3.19e-33	147.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC0R@91061|Bacilli,26R3U@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369,1.1.1.371	ko:K00010,ko:K16044	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951,R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS3_k127_7431256_6	643562.Daes_0603	6.367e-25	121.0	COG0726@1|root,COG0726@2|Bacteria,1R5QW@1224|Proteobacteria,42R0U@68525|delta/epsilon subdivisions,2WN0F@28221|Deltaproteobacteria,2MBI9@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334,Polysacc_deac_1
CMS3_k127_7431256_3	706587.Desti_4725	7.124e-50	196.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gumK	-	2.4.1.264	ko:K07011,ko:K13659	-	-	R09732	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT70	-	Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
CMS3_k127_7431256_4	443143.GM18_1204	8.134e-50	190.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria,43TG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
CMS3_k127_7431256_0	1232410.KI421418_gene2257	9.369e-248	796.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,43TGV@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS3_k127_7442742_0	1229780.BN381_130026	0.0	1103.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,3UWEV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
CMS3_k127_7442742_6	1521187.JPIM01000084_gene674	4.457e-21	106.0	COG0457@1|root,COG0457@2|Bacteria,2G9ET@200795|Chloroflexi,377NS@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS3_k127_7442742_4	686340.Metal_1882	5.384e-32	138.0	COG4339@1|root,COG4339@2|Bacteria,1MZ9X@1224|Proteobacteria,1S59I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7442742_1	391625.PPSIR1_35847	2.414e-190	612.0	COG1902@1|root,COG1902@2|Bacteria,1R4A8@1224|Proteobacteria,42YBR@68525|delta/epsilon subdivisions,2WU33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS3_k127_7442742_2	886293.Sinac_3357	4.875e-153	500.0	COG1252@1|root,COG1252@2|Bacteria,2IXBA@203682|Planctomycetes	203682|Planctomycetes	C	NADH dehydrogenase, FAD-containing subunit	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_7442742_3	314230.DSM3645_17270	3.839e-43	168.0	COG4894@1|root,COG4894@2|Bacteria,2J4CG@203682|Planctomycetes	203682|Planctomycetes	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
CMS3_k127_7442742_8	391625.PPSIR1_00907	2.884e-09	71.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_7442742_5	886293.Sinac_2497	1.638e-23	118.0	COG1595@1|root,COG2373@1|root,COG1595@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K03088,ko:K06894	-	-	-	-	ko00000,ko03021	-	-	-	A2M_N,CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
CMS3_k127_7442742_7	595460.RRSWK_00820	5.575e-16	92.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_744910_3	292459.STH911	8.607e-18	94.0	COG2912@1|root,COG2912@2|Bacteria,1VXJ8@1239|Firmicutes,25294@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
CMS3_k127_744910_2	530564.Psta_1770	2.394e-37	158.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS3_k127_744910_1	1499967.BAYZ01000194_gene3127	2.63e-38	155.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS3_k127_744910_4	468059.AUHA01000005_gene2616	2.65e-06	59.0	COG1722@1|root,COG1722@2|Bacteria,4PA4P@976|Bacteroidetes,1IU2S@117747|Sphingobacteriia	976|Bacteroidetes	L	Exonuclease VII small subunit	-	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS3_k127_744910_0	448385.sce5399	6.249e-78	277.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YWRH@29|Myxococcales	28221|Deltaproteobacteria	L	OB-fold nucleic acid binding domain	-	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS3_k127_7473791_0	395493.BegalDRAFT_2517	1.224e-76	282.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387,ko:K03301	-	-	-	-	ko00000,ko01000,ko01002,ko02042	2.A.12	-	-	DUF1822,DUF4132,HEAT_2,HEAT_PBS,Peptidase_M9,Peptidase_M9_N,Sulfatase
CMS3_k127_7473791_1	867845.KI911784_gene2277	8.703e-56	214.0	COG0457@1|root,COG1404@1|root,COG3055@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_748509_10	886293.Sinac_1635	1.36e-44	169.0	COG0582@1|root,COG0582@2|Bacteria,2IYXX@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS3_k127_748509_23	87626.PTD2_17885	0.0003189	45.0	2DR6A@1|root,33ACN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_748509_21	879212.DespoDRAFT_03369	1.596e-05	55.0	COG5000@1|root,COG5000@2|Bacteria,1RHDM@1224|Proteobacteria,42SJK@68525|delta/epsilon subdivisions,2WPKX@28221|Deltaproteobacteria,2MK9H@213118|Desulfobacterales	28221|Deltaproteobacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_748509_20	1330700.JQNC01000003_gene1007	2.915e-06	59.0	2DVTT@1|root,33X4Y@2|Bacteria,1WKIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
CMS3_k127_748509_19	566461.SSFG_01688	2.312e-11	77.0	COG3321@1|root,COG3321@2|Bacteria,2H477@201174|Actinobacteria	201174|Actinobacteria	Q	polyketide synthase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
CMS3_k127_748509_7	760192.Halhy_1465	1.264e-53	219.0	COG4403@1|root,COG4403@2|Bacteria,4NMZP@976|Bacteroidetes,1IUIF@117747|Sphingobacteriia	976|Bacteroidetes	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like
CMS3_k127_748509_1	68219.JNXI01000054_gene182	1.379e-151	511.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS3_k127_748509_0	1123508.JH636450_gene7162	2.472e-162	541.0	COG1198@1|root,COG1198@2|Bacteria,2IY1F@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS3_k127_748509_14	186497.PF0510	3.846e-25	111.0	COG1694@1|root,arCOG01084@2157|Archaea,2XZ0S@28890|Euryarchaeota,244B1@183968|Thermococci	183968|Thermococci	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS3_k127_748509_15	234267.Acid_1569	3.704e-22	109.0	COG1267@1|root,COG1267@2|Bacteria,3Y4T1@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CMS3_k127_748509_12	243090.RB10878	3.046e-28	121.0	COG0558@1|root,COG0558@2|Bacteria,2IZQ1@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS3_k127_748509_3	457396.CSBG_01748	2.159e-116	393.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,36E1K@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CMS3_k127_748509_11	314230.DSM3645_08757	2.52e-36	142.0	COG0359@1|root,COG0359@2|Bacteria,2IZCC@203682|Planctomycetes	203682|Planctomycetes	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS3_k127_748509_18	1122221.JHVI01000022_gene1216	1.03e-11	71.0	COG0238@1|root,COG0238@2|Bacteria,1WKAE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS3_k127_748509_17	1123508.JH636445_gene6802	1.405e-16	89.0	COG0360@1|root,COG0360@2|Bacteria,2J0U0@203682|Planctomycetes	203682|Planctomycetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS3_k127_748509_9	1051632.TPY_0196	8.673e-45	172.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WCIX@538999|Clostridiales incertae sedis	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS3_k127_748509_16	1123371.ATXH01000007_gene553	1.584e-19	98.0	COG1825@1|root,COG1825@2|Bacteria,2GHKF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS3_k127_748509_4	247490.KSU1_B0544	2.628e-114	378.0	COG0462@1|root,COG0462@2|Bacteria,2IXI0@203682|Planctomycetes	203682|Planctomycetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS3_k127_748509_5	886293.Sinac_6338	8.245e-95	345.0	COG1207@1|root,COG1207@2|Bacteria,2IXXB@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
CMS3_k127_748509_22	1123257.AUFV01000002_gene2374	0.0002797	53.0	COG3562@1|root,COG3562@2|Bacteria,1QBTU@1224|Proteobacteria,1T7E3@1236|Gammaproteobacteria,1X95T@135614|Xanthomonadales	135614|Xanthomonadales	M	Capsule polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Capsule_synth
CMS3_k127_748509_8	1170562.Cal6303_4120	3.369e-53	203.0	COG0457@1|root,COG0457@2|Bacteria,1GE9K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
CMS3_k127_748509_2	1170562.Cal6303_0980	3.288e-151	492.0	COG1222@1|root,COG1222@2|Bacteria,1G1TR@1117|Cyanobacteria,1HM7E@1161|Nostocales	1117|Cyanobacteria	O	Holliday junction DNA helicase ruvB N-terminus	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA
CMS3_k127_748509_6	530564.Psta_2567	1.405e-85	297.0	COG3828@1|root,COG3828@2|Bacteria,2IY8Q@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS3_k127_748509_13	1408813.AYMG01000006_gene4141	3.986e-28	123.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1IRQX@117747|Sphingobacteriia	976|Bacteroidetes	G	Haloacid Dehalogenase Superfamily Class (subfamily) IIA	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS3_k127_7489623_1	357808.RoseRS_3332	8.192e-35	141.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7489623_0	278957.ABEA03000039_gene3482	7.445e-114	383.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS3_k127_7498623_0	1242864.D187_007053	4.146e-05	57.0	COG4932@1|root,COG4932@2|Bacteria,1P94X@1224|Proteobacteria,4333Y@68525|delta/epsilon subdivisions,2WYD5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_7521832_12	1430440.MGMSRv2_0691	1.28e-18	93.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,2JVJD@204441|Rhodospirillales	204441|Rhodospirillales	KL	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
CMS3_k127_7521832_11	448385.sce4871	1.499e-24	114.0	COG1073@1|root,COG3055@1|root,COG1073@2|Bacteria,COG3055@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria,2YYIK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1929)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Glyoxal_oxid_N,Kelch_1,Kelch_4
CMS3_k127_7521832_13	1210884.HG799462_gene8365	1.461e-10	74.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,2J08R@203682|Planctomycetes	203682|Planctomycetes	Q	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP,Peptidase_M10
CMS3_k127_7521832_1	1380355.JNIJ01000011_gene960	2.561e-98	334.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria,3JXTX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS3_k127_7521832_3	908339.HMPREF9265_1630	2.925e-76	283.0	COG1061@1|root,COG1061@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,3F3YQ@33958|Lactobacillaceae	91061|Bacilli	L	Helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
CMS3_k127_7521832_10	1547445.LO80_04195	7.277e-34	151.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,1RPBF@1236|Gammaproteobacteria,460YV@72273|Thiotrichales	72273|Thiotrichales	S	Uncharacterized protein family UPF0029	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
CMS3_k127_7521832_8	357808.RoseRS_3332	1.187e-36	153.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_7521832_6	1121940.AUDZ01000006_gene186	1.075e-39	158.0	COG0742@1|root,COG0742@2|Bacteria,1MX8Z@1224|Proteobacteria,1RMIB@1236|Gammaproteobacteria,1XIK1@135619|Oceanospirillales	135619|Oceanospirillales	J	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	2.1.1.242	ko:K15984	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SAM_MT
CMS3_k127_7521832_9	1395513.P343_03200	6.105e-35	147.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26NDP@186821|Sporolactobacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_7521832_7	1380390.JIAT01000010_gene4850	1.712e-38	162.0	COG0194@1|root,COG0194@2|Bacteria,2GK2M@201174|Actinobacteria,4CQ9S@84995|Rubrobacteria	84995|Rubrobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS3_k127_7521832_5	290397.Adeh_2607	5.112e-42	168.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS3_k127_7521832_14	929562.Emtol_3579	9.527e-05	48.0	COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,47SC6@768503|Cytophagia	976|Bacteroidetes	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS3_k127_7521832_4	357808.RoseRS_3813	9.143e-63	236.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi,3750D@32061|Chloroflexia	32061|Chloroflexia	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS3_k127_7521832_2	429009.Adeg_1912	4.358e-90	316.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,42EJY@68295|Thermoanaerobacterales	186801|Clostridia	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS3_k127_7521832_0	56110.Oscil6304_0217	4.51e-121	413.0	28M30@1|root,2ZAHC@2|Bacteria,1G4Q0@1117|Cyanobacteria,1HEAJ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7606922_0	1192034.CAP_0838	3.49e-247	767.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJBM@28221|Deltaproteobacteria,2YTUN@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS3_k127_7606922_9	1341151.ASZU01000010_gene1900	1.93e-20	93.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,27C7R@186824|Thermoactinomycetaceae	91061|Bacilli	O	NifU-like domain	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
CMS3_k127_7606922_2	1123242.JH636435_gene2591	3.877e-156	508.0	COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes	203682|Planctomycetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
CMS3_k127_7606922_7	945713.IALB_3098	1.342e-35	143.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nifU	-	-	-	-	-	-	-	-	-	-	-	NifU
CMS3_k127_7606922_10	1123242.JH636435_gene1890	3.647e-16	83.0	COG0727@1|root,COG0727@2|Bacteria,2IZM1@203682|Planctomycetes	203682|Planctomycetes	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS3_k127_7606922_4	323261.Noc_0521	1.927e-118	402.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1QTUE@1224|Proteobacteria,1T1HJ@1236|Gammaproteobacteria,1WXTY@135613|Chromatiales	135613|Chromatiales	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS3_k127_7606922_3	1220589.CD32_15670	4.432e-132	451.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3IXE6@400634|Lysinibacillus	91061|Bacilli	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS3_k127_7606922_5	1267535.KB906767_gene1733	1.323e-115	393.0	COG0016@1|root,COG0016@2|Bacteria,3Y3NJ@57723|Acidobacteria,2JIN8@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS3_k127_7606922_8	445972.ANACOL_03010	1.199e-31	127.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WIYY@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS3_k127_7606922_12	546269.HMPREF0389_00750	2.9e-06	55.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,25RWU@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS3_k127_7606922_6	1168059.KB899087_gene3453	1.533e-48	179.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,3EY69@335928|Xanthobacteraceae	28211|Alphaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS3_k127_7606922_1	1266914.ATUK01000016_gene386	1.937e-222	708.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,1WVYK@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS3_k127_785186_5	1122939.ATUD01000001_gene577	1.128e-100	363.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_785186_1	1122939.ATUD01000001_gene577	5.514e-195	649.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_785186_9	706587.Desti_5641	1.625e-07	62.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2MQFG@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_785186_7	1463853.JOHW01000008_gene714	5.327e-19	95.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31,Ubie_methyltran
CMS3_k127_785186_8	1157943.KB892705_gene3941	6.001e-14	81.0	COG0348@1|root,COG1251@1|root,COG0348@2|Bacteria,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,2389K@1762|Mycobacteriaceae	201174|Actinobacteria	C	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Fer2,Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
CMS3_k127_785186_6	446470.Snas_1211	3.136e-32	138.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria	2|Bacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Methyltransf_25,RrnaAD
CMS3_k127_785186_4	246197.MXAN_4981	8.036e-105	350.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,42MZG@68525|delta/epsilon subdivisions,2WKZ3@28221|Deltaproteobacteria,2YTT5@29|Myxococcales	28221|Deltaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
CMS3_k127_785186_2	502025.Hoch_0235	4.482e-179	569.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42PKM@68525|delta/epsilon subdivisions,2WJCP@28221|Deltaproteobacteria,2YUCG@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS3_k127_785186_3	497964.CfE428DRAFT_5214	5.912e-179	576.0	COG2425@1|root,COG2425@2|Bacteria,46UN1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	TROVE domain	-	-	-	-	-	-	-	-	-	-	-	-	TROVE
CMS3_k127_785186_0	378806.STAUR_5805	2.34e-216	685.0	COG4650@1|root,COG4650@2|Bacteria,1MX6U@1224|Proteobacteria,42NHB@68525|delta/epsilon subdivisions,2WKUB@28221|Deltaproteobacteria,2YTU9@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-54 dependent transcriptional regulator	rtcR	-	-	ko:K14414	-	-	-	-	ko00000,ko03000	-	-	-	RtcR,Sigma54_activat
CMS3_k127_798606_1	756272.Plabr_2883	1.537e-80	284.0	COG0515@1|root,COG0515@2|Bacteria,2J2D5@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS3_k127_798606_0	100226.SCO1275	3.071e-122	413.0	COG0644@1|root,COG0644@2|Bacteria,2GIWW@201174|Actinobacteria	201174|Actinobacteria	C	halogenase	-	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
CMS3_k127_798606_2	1458275.AZ34_07535	3.809e-74	258.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VMFC@28216|Betaproteobacteria,4AFKG@80864|Comamonadaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS3_k127_798606_3	1151126.AQYI01000006_gene2751	4.062e-08	64.0	COG4932@1|root,COG4932@2|Bacteria,2HU92@201174|Actinobacteria,4FSW9@85023|Microbacteriaceae	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_79939_4	391625.PPSIR1_41779	2.51e-131	445.0	COG3303@1|root,COG3303@2|Bacteria,1QX6Q@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
CMS3_k127_79939_17	1158338.JNLJ01000005_gene1340	1.026e-18	101.0	COG3005@1|root,COG3005@2|Bacteria,2G4HN@200783|Aquificae	200783|Aquificae	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS3_k127_79939_3	463191.SSEG_09893	9.393e-141	460.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_79939_13	861299.J421_2147	8.598e-28	120.0	COG3795@1|root,COG3795@2|Bacteria,1ZV0M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_79939_7	1123242.JH636434_gene5055	1.382e-79	293.0	COG3386@1|root,COG3386@2|Bacteria,2IXWY@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS3_k127_79939_6	1288963.ADIS_3293	1.072e-98	350.0	28JXN@1|root,2Z9N3@2|Bacteria,4NJUA@976|Bacteroidetes,47NJF@768503|Cytophagia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CMS3_k127_79939_8	105425.BBPL01000063_gene5278	1.874e-74	261.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,2NF8W@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_79939_15	234267.Acid_1882	1.104e-21	104.0	2DF1J@1|root,2ZQ4G@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS3_k127_79939_22	985054.JQEZ01000002_gene3275	2.246e-10	72.0	COG2128@1|root,COG2128@2|Bacteria,1PQ1G@1224|Proteobacteria,2U17A@28211|Alphaproteobacteria,4NBJF@97050|Ruegeria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_79939_19	460265.Mnod_4522	1.744e-12	71.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,1JTZJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS3_k127_79939_24	644282.Deba_2753	0.0006325	50.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42WMZ@68525|delta/epsilon subdivisions,2WRXF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS3_k127_79939_5	913865.DOT_2597	5.589e-107	376.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,260IT@186807|Peptococcaceae	186801|Clostridia	U	PFAM Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS3_k127_79939_0	240016.ABIZ01000001_gene1515	9.538e-294	944.0	COG2319@1|root,COG2319@2|Bacteria,46UES@74201|Verrucomicrobia	74201|Verrucomicrobia	S	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PSCyt1,PSCyt2,PSD1,WD40
CMS3_k127_79939_1	1340493.JNIF01000004_gene277	1.218e-202	642.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS3_k127_79939_12	344747.PM8797T_11209	3.297e-29	138.0	COG2319@1|root,COG2319@2|Bacteria,2J53E@203682|Planctomycetes	203682|Planctomycetes	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_79939_11	497964.CfE428DRAFT_2433	3.411e-32	148.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CMS3_k127_79939_23	1379698.RBG1_1C00001G1750	5.979e-07	60.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS3_k127_79939_10	314230.DSM3645_23261	7.788e-44	175.0	28I0W@1|root,30QX6@2|Bacteria,2IZI8@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_79939_2	1121904.ARBP01000001_gene5603	2.577e-162	522.0	COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,47KZS@768503|Cytophagia	976|Bacteroidetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS3_k127_79939_18	243090.RB12730	8.751e-17	91.0	COG1595@1|root,COG1595@2|Bacteria,2J3KY@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_79939_20	709991.Odosp_3404	7.474e-12	76.0	COG4232@1|root,COG4232@2|Bacteria,4NH5B@976|Bacteroidetes,2FWD6@200643|Bacteroidia,22ZJ9@171551|Porphyromonadaceae	976|Bacteroidetes	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CMS3_k127_79939_16	765913.ThidrDRAFT_3225	4.883e-19	86.0	COG2343@1|root,COG2343@2|Bacteria,1N1K4@1224|Proteobacteria,1SE87@1236|Gammaproteobacteria,1WZJ6@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS3_k127_79939_21	1386089.N865_07270	4.998e-11	64.0	COG2343@1|root,COG2343@2|Bacteria,2HXN4@201174|Actinobacteria,4FHF3@85021|Intrasporangiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS3_k127_79939_9	243090.RB3867	1.151e-44	174.0	COG3568@1|root,COG3568@2|Bacteria,2J2R6@203682|Planctomycetes	203682|Planctomycetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS3_k127_899159_13	1267535.KB906767_gene447	3.825e-112	381.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria,2JMN2@204432|Acidobacteriia	204432|Acidobacteriia	T	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS3_k127_899159_24	1163617.SCD_n01877	4.011e-36	159.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
CMS3_k127_899159_3	344747.PM8797T_11571	1.341e-164	549.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,2IXTF@203682|Planctomycetes	203682|Planctomycetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_899159_10	1403819.BATR01000181_gene6053	6.215e-115	383.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia,2IUNH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS3_k127_899159_0	344747.PM8797T_30566	7.395e-197	623.0	COG1012@1|root,COG1012@2|Bacteria,2IXUV@203682|Planctomycetes	203682|Planctomycetes	C	COG1012 NAD-dependent aldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS3_k127_899159_5	1403819.BATR01000181_gene6055	1.244e-158	506.0	COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_899159_6	314230.DSM3645_18936	3.183e-157	523.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS3_k127_899159_26	756272.Plabr_2308	7.7e-16	80.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
CMS3_k127_899159_8	497964.CfE428DRAFT_5031	7.529e-157	544.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS3_k127_899159_2	1403819.BATR01000181_gene6057	4.217e-192	633.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_899159_21	324602.Caur_0649	7.061e-60	231.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
CMS3_k127_899159_20	215803.DB30_7287	7.46e-67	244.0	COG1317@1|root,COG1317@2|Bacteria,1QE2R@1224|Proteobacteria,438GQ@68525|delta/epsilon subdivisions,2X3RI@28221|Deltaproteobacteria,2YWXQ@29|Myxococcales	28221|Deltaproteobacteria	NU	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_899159_17	575540.Isop_2875	7.764e-96	328.0	COG4864@1|root,COG4864@2|Bacteria,2IXDK@203682|Planctomycetes	203682|Planctomycetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS3_k127_899159_22	497964.CfE428DRAFT_6360	3.536e-39	151.0	COG0509@1|root,COG0509@2|Bacteria,46WCE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
CMS3_k127_899159_12	497964.CfE428DRAFT_4253	2.207e-112	384.0	COG0523@1|root,COG0523@2|Bacteria,46URF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SRP54-type protein, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
CMS3_k127_899159_25	497964.CfE428DRAFT_6361	1.091e-28	126.0	2FICZ@1|root,34A57@2|Bacteria,46W7Z@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_899159_18	497964.CfE428DRAFT_6362	1.542e-88	306.0	COG1146@1|root,COG1146@2|Bacteria,46TI2@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_899159_4	1123242.JH636435_gene1438	5.417e-161	533.0	COG0535@1|root,COG0535@2|Bacteria,2IX8N@203682|Planctomycetes	203682|Planctomycetes	S	enzyme of the MoaA nifB pqqE family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS3_k127_899159_1	497964.CfE428DRAFT_0155	2.702e-193	625.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,46TEA@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116,polyprenyl_synt
CMS3_k127_899159_9	497964.CfE428DRAFT_0160	1.381e-155	523.0	COG1657@1|root,COG1657@2|Bacteria,46UEC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
CMS3_k127_899159_14	1382359.JIAL01000001_gene821	1.225e-107	361.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_899159_11	240016.ABIZ01000001_gene3008	9.868e-113	381.0	COG1520@1|root,COG1520@2|Bacteria,46U6I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_899159_19	344747.PM8797T_21393	2.376e-81	287.0	COG0644@1|root,COG0644@2|Bacteria,2IX1U@203682|Planctomycetes	203682|Planctomycetes	C	COG0644 Dehydrogenases (flavoproteins)	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CMS3_k127_899159_15	1123242.JH636434_gene3999	1.798e-98	347.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS3_k127_899159_7	240016.ABIZ01000001_gene3202	5.282e-157	511.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_899159_23	497964.CfE428DRAFT_4947	5.731e-39	151.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS3_k127_899159_16	595460.RRSWK_07140	2.681e-97	346.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_947821_0	1242864.D187_001578	1.7e-127	421.0	COG2103@1|root,COG2103@2|Bacteria,1Q58C@1224|Proteobacteria,430SB@68525|delta/epsilon subdivisions,2WW60@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
CMS3_k127_947821_5	1443665.JACA01000007_gene234	2.322e-61	217.0	COG4430@1|root,COG4430@2|Bacteria,4NKNI@976|Bacteroidetes,1I11I@117743|Flavobacteriia,2YI5V@290174|Aquimarina	976|Bacteroidetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
CMS3_k127_947821_7	177437.HRM2_24450	1.174e-43	172.0	COG0767@1|root,COG0767@2|Bacteria,1N2HV@1224|Proteobacteria,42UV1@68525|delta/epsilon subdivisions,2WQXM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS3_k127_947821_9	940282.CADQ01000101_gene1428	3.037e-24	115.0	COG3839@1|root,COG3839@2|Bacteria,1QWQS@1224|Proteobacteria,2UUMH@28211|Alphaproteobacteria,2JXJV@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the ABC transporter superfamily	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	-
CMS3_k127_947821_8	177437.HRM2_24430	1.751e-29	131.0	COG1463@1|root,COG1463@2|Bacteria,1PP5K@1224|Proteobacteria,43EVP@68525|delta/epsilon subdivisions,2WT7Z@28221|Deltaproteobacteria,2MP7C@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS3_k127_947821_12	177437.HRM2_24410	4e-15	89.0	COG0457@1|root,COG0457@2|Bacteria	177437.HRM2_24410|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_947821_6	452637.Oter_1311	1.408e-57	212.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_947821_4	378806.STAUR_0140	3.67e-66	244.0	COG1317@1|root,COG1317@2|Bacteria,1QE2R@1224|Proteobacteria,438GQ@68525|delta/epsilon subdivisions,2X3RI@28221|Deltaproteobacteria,2YWXQ@29|Myxococcales	28221|Deltaproteobacteria	NU	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_947821_2	502025.Hoch_4422	8.019e-82	276.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,43B5T@68525|delta/epsilon subdivisions,2X6JE@28221|Deltaproteobacteria,2Z3BD@29|Myxococcales	28221|Deltaproteobacteria	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS3_k127_947821_3	595460.RRSWK_02446	2.42e-80	285.0	COG1680@1|root,COG1680@2|Bacteria,2IZXU@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS3_k127_947821_14	1123037.AUDE01000023_gene2792	9.123e-09	65.0	2E3AK@1|root,320TI@2|Bacteria,4NRX2@976|Bacteroidetes,1IIAU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_947821_15	246197.MXAN_4396	1.717e-07	65.0	COG3485@1|root,COG3485@2|Bacteria,1QXUR@1224|Proteobacteria,43C7D@68525|delta/epsilon subdivisions,2X7HP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS3_k127_947821_13	450851.PHZ_c0249	2.072e-09	71.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U182@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS3_k127_947821_1	344747.PM8797T_11259	1.207e-112	380.0	COG1082@1|root,COG1082@2|Bacteria,2IY3R@203682|Planctomycetes	203682|Planctomycetes	G	ioli protein	-	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS3_k127_947821_10	706587.Desti_1071	2.162e-21	100.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2MQN7@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Universal stress protein family	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
CMS3_k127_947821_11	797304.Natgr_3038	9.447e-18	92.0	COG0517@1|root,arCOG00606@2157|Archaea,2Y03P@28890|Euryarchaeota,23XS4@183963|Halobacteria	183963|Halobacteria	S	Signal transduction protein with CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_958718_8	944481.JAFP01000001_gene757	3.47e-35	153.0	COG0618@1|root,COG0618@2|Bacteria,1RAUQ@1224|Proteobacteria,42RKG@68525|delta/epsilon subdivisions,2WN0X@28221|Deltaproteobacteria,2M725@213113|Desulfurellales	28221|Deltaproteobacteria	S	DHHA1 domain	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS3_k127_958718_6	1123371.ATXH01000019_gene623	1.17e-41	168.0	COG0402@1|root,COG0402@2|Bacteria,2GHA4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Amidohydrolase family	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS3_k127_958718_12	4787.PITG_07873T0	2.64e-05	58.0	28K2B@1|root,2QSGV@2759|Eukaryota,3QE25@4776|Peronosporales	4776|Peronosporales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS3_k127_958718_10	240015.ACP_1172	2.611e-20	108.0	COG0457@1|root,COG0457@2|Bacteria,3Y77J@57723|Acidobacteria,2JM29@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS3_k127_958718_7	436229.JOEH01000009_gene4709	2.258e-39	169.0	COG0438@1|root,COG0438@2|Bacteria,2IA6D@201174|Actinobacteria,2NKZP@228398|Streptacidiphilus	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS3_k127_958718_4	768671.ThimaDRAFT_3471	3.318e-87	303.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1WXRS@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS3_k127_958718_11	204669.Acid345_1569	1.32e-10	70.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS3_k127_958718_3	497964.CfE428DRAFT_3562	4.093e-95	325.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS3_k127_958718_1	639282.DEFDS_1109	3.227e-145	479.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS3_k127_958718_2	639282.DEFDS_1110	7.688e-124	410.0	COG2805@1|root,COG2805@2|Bacteria,2GEWK@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS3_k127_958718_0	580340.Tlie_1250	8.327e-147	488.0	COG0480@1|root,COG0480@2|Bacteria,3TA2B@508458|Synergistetes	508458|Synergistetes	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_958718_9	237368.SCABRO_03873	3.581e-23	109.0	COG1360@1|root,COG1360@2|Bacteria,2IZSF@203682|Planctomycetes	203682|Planctomycetes	N	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS3_k127_958718_5	118166.JH976537_gene3497	3.108e-44	173.0	COG1989@1|root,COG1989@2|Bacteria,1FZZA@1117|Cyanobacteria,1H7ST@1150|Oscillatoriales	1117|Cyanobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	hofD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS3_k127_975863_1	382464.ABSI01000011_gene3187	2.168e-87	314.0	COG0815@1|root,COG0815@2|Bacteria,46W4F@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_975863_2	926550.CLDAP_02300	3.168e-45	186.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi	200795|Chloroflexi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_975863_0	448385.sce5308	2.382e-130	442.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2YU9C@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS3_k127_975863_4	243090.RB13330	7.283e-13	82.0	COG0457@1|root,COG5305@1|root,COG0457@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_975863_3	228410.NE0622	4.015e-23	105.0	COG0662@1|root,COG0662@2|Bacteria,1RFTK@1224|Proteobacteria,2WG1F@28216|Betaproteobacteria,374QB@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_981901_4	1499967.BAYZ01000118_gene3248	6.808e-31	140.0	COG0845@1|root,COG0845@2|Bacteria,2NR8R@2323|unclassified Bacteria	2|Bacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,HlyD_D23
CMS3_k127_981901_3	1232437.KL662020_gene699	1.703e-31	143.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS3_k127_981901_0	1122939.ATUD01000001_gene577	5.839e-203	678.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_981901_2	575540.Isop_2164	7.052e-77	269.0	COG1432@1|root,COG1432@2|Bacteria,2IY4C@203682|Planctomycetes	203682|Planctomycetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS3_k127_981901_1	344747.PM8797T_08629	1.534e-103	350.0	COG1520@1|root,COG1520@2|Bacteria,2J26V@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS3_k127_981901_5	489825.LYNGBM3L_25840	1.193e-07	65.0	COG3420@1|root,COG3420@2|Bacteria,1G2FG@1117|Cyanobacteria,1H7WG@1150|Oscillatoriales	1117|Cyanobacteria	P	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1565,SLH
## 4947 queries scanned
## Total time (seconds): 469.6587677001953
## Rate: 10.53 q/s