## Mon Feb 16 08:01:06 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/CMS3_bin.89.fa -m mmseqs --output CMS3_bin.89 --output_dir /data/result/bins/wyx/eggqs50+/CMS3_bin.89 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS3_k127_1014286_1	436308.Nmar_0700	7.255e-115	376.0	arCOG04054@1|root,arCOG04054@2157|Archaea,41SIQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1014286_2	1229909.NSED_04760	2.359e-99	332.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
CMS3_k127_1014286_0	436308.Nmar_0701	0.0	1040.0	COG0365@1|root,arCOG04201@2157|Archaea	2157|Archaea	I	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS3_k127_1014286_3	436308.Nmar_0702	1.069e-68	237.0	arCOG06712@1|root,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9
CMS3_k127_1014286_4	436308.Nmar_1282	7.556e-23	102.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_19	1229909.NSED_03260	1.009e-68	234.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_1019060_13	1229909.NSED_03265	2.193e-123	401.0	COG2084@1|root,arCOG00247@2157|Archaea,41SI2@651137|Thaumarchaeota	651137|Thaumarchaeota	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS3_k127_1019060_20	436308.Nmar_0636	1.278e-58	205.0	arCOG08654@1|root,arCOG08654@2157|Archaea,41SRM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_24	1229909.NSED_03275	2.079e-46	169.0	arCOG10531@1|root,arCOG10531@2157|Archaea,41T4F@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_33	436308.Nmar_0638	2.756e-10	63.0	arCOG08725@1|root,arCOG08725@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_17	1229909.NSED_03290	5.663e-98	325.0	COG1651@1|root,arCOG02868@2157|Archaea,41T1M@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_1019060_21	1229909.NSED_03295	5.886e-57	202.0	arCOG08653@1|root,arCOG08653@2157|Archaea,41T9H@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_12	436308.Nmar_0976	1.092e-127	415.0	COG0614@1|root,arCOG04233@2157|Archaea,41SXD@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS3_k127_1019060_4	436308.Nmar_0975	1.537e-197	620.0	COG1602@1|root,arCOG04269@2157|Archaea,41S7H@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Archaeal Nre, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
CMS3_k127_1019060_11	436308.Nmar_0641	9.409e-152	484.0	arCOG08669@1|root,arCOG08669@2157|Archaea,41SEB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_9	436308.Nmar_0642	3.701e-160	511.0	COG0389@1|root,arCOG04582@2157|Archaea,41SDV@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis	dbh	-	2.7.7.7	ko:K04479	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS3_k127_1019060_29	1229909.NSED_03315	3.385e-24	104.0	arCOG08668@1|root,arCOG08668@2157|Archaea,41SW4@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_23	1229909.NSED_03320	7.712e-49	179.0	COG1581@1|root,arCOG03441@1|root,arCOG01753@2157|Archaea,arCOG03441@2157|Archaea,41T5A@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Alba	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
CMS3_k127_1019060_32	1229909.NSED_03325	1.334e-14	76.0	arCOG10532@1|root,arCOG10532@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_18	1229909.NSED_03335	4.206e-95	317.0	COG1938@1|root,arCOG00347@2157|Archaea,41T2Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
CMS3_k127_1019060_6	1229909.NSED_03340	8.542e-179	563.0	COG1899@1|root,arCOG04142@2157|Archaea,41SDB@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CMS3_k127_1019060_3	436308.Nmar_0649	3.255e-217	677.0	COG1260@1|root,arCOG04213@2157|Archaea,41SEZ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
CMS3_k127_1019060_15	1229909.NSED_03350	1.656e-103	342.0	COG0388@1|root,arCOG00062@2157|Archaea	2157|Archaea	H	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS3_k127_1019060_25	1229909.NSED_07005	1.99e-42	159.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_0	1229909.NSED_03355	0.0	1618.0	COG1196@1|root,arCOG00371@2157|Archaea,41SDS@651137|Thaumarchaeota	651137|Thaumarchaeota	D	SMC proteins Flexible Hinge Domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS3_k127_1019060_8	436308.Nmar_0652	7.508e-163	516.0	COG4608@1|root,arCOG00184@2157|Archaea,41S9E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS3_k127_1019060_10	1229909.NSED_03365	6.089e-159	506.0	COG4301@1|root,arCOG06722@2157|Archaea,41SWR@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
CMS3_k127_1019060_2	436308.Nmar_0657	2.075e-245	762.0	COG1262@1|root,arCOG03517@2157|Archaea,41T1B@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS3_k127_1019060_7	436308.Nmar_1385	4.539e-172	546.0	COG0731@1|root,arCOG00953@2157|Archaea	2157|Archaea	C	Radical SAM domain protein	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
CMS3_k127_1019060_1	436308.Nmar_0658	2.889e-265	821.0	COG0008@1|root,arCOG00402@2157|Archaea,41SFI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
CMS3_k127_1019060_26	1131266.ARWQ01000011_gene103	4.231e-41	153.0	arCOG07440@1|root,arCOG07440@2157|Archaea,41STP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_31	1304284.L21TH_2247	2.993e-15	81.0	COG2204@1|root,COG2204@2|Bacteria,1UHXE@1239|Firmicutes,25E6A@186801|Clostridia,36UNF@31979|Clostridiaceae	186801|Clostridia	T	cheY-homologous receiver domain	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_1019060_14	436308.Nmar_0666	9.561e-116	376.0	COG0560@1|root,arCOG01158@2157|Archaea,41SHX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
CMS3_k127_1019060_16	1229909.NSED_03390	2.924e-100	331.0	COG1478@1|root,arCOG02714@2157|Archaea,41T27@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
CMS3_k127_1019060_27	1229909.NSED_03505	3.435e-40	149.0	COG0425@1|root,arCOG02062@2157|Archaea,41SU5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
CMS3_k127_1019060_5	436308.Nmar_0670	1.523e-195	612.0	COG0031@1|root,arCOG01430@2157|Archaea,41SYM@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine synthase	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_1019060_28	436308.Nmar_0671	4.595e-35	139.0	arCOG10533@1|root,arCOG10533@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1019060_22	436308.Nmar_0672	4.303e-50	178.0	COG0492@1|root,arCOG01296@2157|Archaea,41S97@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_105685_0	1229909.NSED_05255	0.0	1078.0	arCOG11939@1|root,arCOG11939@2157|Archaea	1229909.NSED_05255|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1059299_2	1286632.P278_26420	8.593e-50	180.0	COG2350@1|root,COG2350@2|Bacteria,4NNMS@976|Bacteroidetes,1I22W@117743|Flavobacteriia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS3_k127_1059299_1	1380600.AUYN01000007_gene3214	4.52e-72	245.0	COG2954@1|root,COG2954@2|Bacteria,4NNGE@976|Bacteroidetes,1I1YE@117743|Flavobacteriia	976|Bacteroidetes	S	Adenylate cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
CMS3_k127_1059299_0	1197477.IA57_05875	1.008e-120	389.0	COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia	976|Bacteroidetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS3_k127_1140211_1	1459636.NTE_01953	1.263e-57	206.0	COG1685@1|root,arCOG01025@2157|Archaea,41SGZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	GHMP kinases N terminal domain	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS3_k127_1140211_0	436308.Nmar_0548	2.151e-153	489.0	COG0128@1|root,arCOG04134@2157|Archaea,41S5I@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS3_k127_1208293_7	1131266.ARWQ01000001_gene1236	3.887e-24	106.0	COG0367@1|root,arCOG00071@2157|Archaea,41SXI@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
CMS3_k127_1208293_0	1220534.B655_0758	1.555e-97	335.0	COG0677@1|root,arCOG00252@2157|Archaea,2XUCC@28890|Euryarchaeota,23PXN@183925|Methanobacteria	183925|Methanobacteria	M	UDP binding domain	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS3_k127_1208293_2	1131266.ARWQ01000001_gene1240	4.46e-86	293.0	COG0451@1|root,arCOG01369@2157|Archaea,41T3U@651137|Thaumarchaeota	651137|Thaumarchaeota	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS3_k127_1208293_6	1131266.ARWQ01000001_gene1237	4.181e-43	169.0	COG0438@1|root,arCOG01403@2157|Archaea,41SWW@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS3_k127_1208293_4	436308.Nmar_1592	1.623e-62	216.0	arCOG07348@1|root,arCOG07348@2157|Archaea,41SUQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208293_3	1229909.NSED_08620	4.183e-71	246.0	arCOG10593@1|root,arCOG10593@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208293_1	1229909.NSED_08625	1.42e-93	311.0	arCOG08773@1|root,arCOG08773@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208293_5	1229909.NSED_08635	1.744e-55	196.0	arCOG10592@1|root,arCOG10594@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_31	1042377.AFPJ01000027_gene2670	1.445e-21	110.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,4672D@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Glyco_18	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ
CMS3_k127_1208905_15	1304885.AUEY01000014_gene3322	1.02e-71	264.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2MKXA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
CMS3_k127_1208905_23	1229909.NSED_05260	8.737e-41	159.0	arCOG02416@1|root,arCOG02416@2157|Archaea	2157|Archaea	S	Archaeal Type IV pilin, N-terminal	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PKD,Pilin_N
CMS3_k127_1208905_13	436308.Nmar_1271	1.427e-76	265.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_1208905_21	1229909.NSED_06550	9.892e-44	164.0	arCOG08634@1|root,arCOG08634@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_11	1229909.NSED_06555	1.052e-103	338.0	COG0221@1|root,arCOG01711@2157|Archaea,41T3F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS3_k127_1208905_27	1229909.NSED_06560	1.679e-34	133.0	arCOG06790@1|root,arCOG06790@2157|Archaea,41T7J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
CMS3_k127_1208905_24	1229909.NSED_02975	5.048e-40	153.0	COG0517@1|root,arCOG00606@2157|Archaea,41T8N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_1208905_1	436308.Nmar_1177	3.699e-305	945.0	COG1164@1|root,arCOG04758@2157|Archaea,41S7J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS3_k127_1208905_14	436308.Nmar_1178	6.68e-74	253.0	arCOG11736@1|root,arCOG11736@2157|Archaea,41T70@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_6	1229909.NSED_06590	2.046e-140	455.0	arCOG08686@1|root,arCOG08686@2157|Archaea,41T56@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_9	436308.Nmar_1180	9.709e-105	341.0	COG1945@1|root,arCOG04490@2157|Archaea,41SPZ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
CMS3_k127_1208905_8	436308.Nmar_1181	4.866e-109	360.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	ko:K21990	-	-	-	-	ko00000	1.A.16.4	-	-	Form_Nir_trans,Thioredoxin_4
CMS3_k127_1208905_2	436308.Nmar_1182	2.707e-239	744.0	COG0513@1|root,arCOG00558@2157|Archaea,41SM1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
CMS3_k127_1208905_26	1229909.NSED_06615	6.74e-36	137.0	COG1522@1|root,arCOG01117@2157|Archaea,41T6G@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
CMS3_k127_1208905_18	1229909.NSED_03715	1.357e-54	192.0	arCOG03272@1|root,arCOG03272@2157|Archaea,41T3V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_25	1229909.NSED_06755	1.988e-36	139.0	arCOG08688@1|root,arCOG08688@2157|Archaea,41T55@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_19	436308.Nmar_1185	9.01e-53	190.0	arCOG08689@1|root,arCOG08689@2157|Archaea,41T5U@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_7	211165.AJLN01000098_gene5131	6.092e-122	397.0	COG1741@1|root,COG1741@2|Bacteria,1G41Z@1117|Cyanobacteria,1JJVK@1189|Stigonemataceae	1117|Cyanobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS3_k127_1208905_12	436308.Nmar_1186	1.785e-91	307.0	arCOG08642@1|root,arCOG08642@2157|Archaea,41T1T@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_22	436308.Nmar_1189	1.769e-42	157.0	arCOG08691@1|root,arCOG08691@2157|Archaea,41T93@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_20	1229909.NSED_06775	3.028e-51	183.0	arCOG08080@1|root,arCOG08080@2157|Archaea,41SUA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_0	436308.Nmar_1191	0.0	1115.0	COG1331@1|root,arCOG02007@2157|Archaea,41SHZ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
CMS3_k127_1208905_30	436308.Nmar_1192	1.195e-26	110.0	arCOG08692@1|root,arCOG08692@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_5	436308.Nmar_1193	2.238e-185	583.0	COG1064@1|root,arCOG01455@2157|Archaea,41SK3@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_1208905_33	1131266.ARWQ01000004_gene1399	4.366e-15	76.0	28HBE@1|root,2N5BC@2157|Archaea,41T8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_29	1229909.NSED_06795	5.024e-28	114.0	arCOG10408@1|root,arCOG10408@2157|Archaea,41T82@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_17	436308.Nmar_1194	4.329e-63	222.0	arCOG08693@1|root,arCOG08693@2157|Archaea,41T7N@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_28	436308.Nmar_1195	5.261e-29	118.0	arCOG10579@1|root,arCOG10579@2157|Archaea,41TAI@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_10	436308.Nmar_1196	1.749e-104	343.0	arCOG08694@1|root,arCOG08694@2157|Archaea,41SZ1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1208905_4	436308.Nmar_1198	5.594e-186	588.0	COG0585@1|root,arCOG04252@2157|Archaea,41S7C@651137|Thaumarchaeota	651137|Thaumarchaeota	J	tRNA pseudouridine synthase	-	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS3_k127_1208905_3	1229909.NSED_06830	1.74e-223	704.0	COG4257@1|root,arCOG03564@2157|Archaea,41SM7@651137|Thaumarchaeota	651137|Thaumarchaeota	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
CMS3_k127_1208905_16	1229909.NSED_06835	4.466e-68	234.0	COG1990@1|root,arCOG04228@2157|Archaea,41ST1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Peptidyl-tRNA hydrolase PTH2	-	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
CMS3_k127_1216079_1	1229909.NSED_01000	1.12e-70	242.0	COG1063@1|root,arCOG01459@2157|Archaea	2157|Archaea	C	Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
CMS3_k127_1216079_3	314230.DSM3645_17555	3.634e-05	54.0	COG0642@1|root,COG0642@2|Bacteria,2J529@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS3_k127_1216079_2	1229909.NSED_00910	2.228e-64	225.0	COG3794@1|root,arCOG02926@2157|Archaea	1229909.NSED_00910|-	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1216079_0	436308.Nmar_0471	0.0	1008.0	COG1948@1|root,arCOG02284@2157|Archaea,41T0R@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
CMS3_k127_1271419_1	1229909.NSED_06845	7.9e-137	439.0	COG0644@1|root,arCOG00570@2157|Archaea,41SB5@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1271419_3	1229909.NSED_06850	5.719e-36	136.0	COG2888@1|root,arCOG01989@2157|Archaea,41T83@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Zn-ribbon RNA-binding protein with a function in translation	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_1271419_2	436308.Nmar_1222	4.855e-37	141.0	COG2092@1|root,arCOG01988@2157|Archaea,41SS1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
CMS3_k127_1271419_0	436308.Nmar_1223	2.654e-259	801.0	COG0464@1|root,arCOG01308@2157|Archaea,41S7X@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cell division protein 48 (CDC48) domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
CMS3_k127_127519_3	436308.Nmar_0620	9.994e-80	267.0	COG3356@1|root,arCOG04351@2157|Archaea,41S7S@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Predicted membrane protein (DUF2070)	-	-	-	ko:K08979	-	-	-	-	ko00000	-	-	-	DUF2070
CMS3_k127_127519_2	1229909.NSED_03185	6.864e-93	309.0	arCOG03727@1|root,arCOG03727@2157|Archaea,41STD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
CMS3_k127_127519_0	1229909.NSED_03180	0.0	1215.0	COG3889@1|root,arCOG01672@2157|Archaea,41SA5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS3_k127_127519_4	1229909.NSED_03175	1.727e-76	259.0	COG2042@1|root,arCOG04733@2157|Archaea,41SMC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Ribosome biogenesis protein, C-terminal	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
CMS3_k127_127519_1	436308.Nmar_0616	0.0	1165.0	arCOG08231@1|root,arCOG08231@2157|Archaea,41T6Q@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CMS3_k127_131635_1	1229909.NSED_00685	1.143e-80	273.0	arCOG05195@1|root,arCOG05195@2157|Archaea	2157|Archaea	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_6,TPR_8
CMS3_k127_131635_0	436308.Nmar_1563	5.118e-168	530.0	COG1736@1|root,arCOG04112@2157|Archaea,41SE0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Diphthamide biosynthesis	-	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
CMS3_k127_1338535_0	436308.Nmar_1488	7.364e-264	821.0	COG0072@1|root,arCOG00412@2157|Archaea,41S8M@651137|Thaumarchaeota	651137|Thaumarchaeota	J	phenylalanyl-tRNA synthetase, beta subunit	-	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5
CMS3_k127_1338535_1	224325.AF_1955	8.577e-93	321.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,245SE@183980|Archaeoglobi	183980|Archaeoglobi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
CMS3_k127_13674_4	436308.Nmar_0807	3.137e-44	162.0	COG0089@1|root,arCOG04072@2157|Archaea,41SS4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome	rpl23	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS3_k127_13674_3	436308.Nmar_0808	7.404e-128	413.0	COG0469@1|root,arCOG04071@2157|Archaea,41SHB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L4	-	-	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS3_k127_13674_0	436308.Nmar_0809	3.593e-177	559.0	COG0087@1|root,arCOG04070@2157|Archaea,41SDN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein L3	-	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS3_k127_13674_2	436308.Nmar_0810	1.3e-130	421.0	COG2106@1|root,arCOG04069@2157|Archaea,41SI7@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative RNA methyltransferase	-	-	-	ko:K09142	-	-	-	-	ko00000	-	-	-	Methyltrn_RNA_3
CMS3_k127_13674_1	1229909.NSED_04495	1.137e-132	426.0	COG0638@1|root,arCOG00971@2157|Archaea,41SYA@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Proteasome endopeptidase complex	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
CMS3_k127_13674_5	1229909.NSED_04500	1.674e-06	49.0	COG2090@1|root,arCOG04171@2157|Archaea,41SNF@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF371)	-	-	-	ko:K09738	-	-	-	-	ko00000	-	-	-	DUF371
CMS3_k127_1433226_2	436308.Nmar_1089	1.411e-30	124.0	arCOG08707@1|root,arCOG08707@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1433226_1	436308.Nmar_1090	1.741e-48	179.0	COG5491@1|root,arCOG00452@2157|Archaea	2157|Archaea	N	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	Snf7
CMS3_k127_1433226_0	436308.Nmar_1091	2.017e-192	606.0	COG1378@1|root,arCOG02037@2157|Archaea,41T17@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
CMS3_k127_1433226_3	1229909.NSED_06360	5.351e-21	93.0	COG0251@1|root,arCOG01630@2157|Archaea,41T4N@651137|Thaumarchaeota	651137|Thaumarchaeota	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS3_k127_1436534_1	1229909.NSED_04320	3.964e-102	333.0	COG0047@1|root,arCOG00102@2157|Archaea,41SG3@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CMS3_k127_1436534_3	436308.Nmar_0778	9.515e-53	189.0	COG0517@1|root,arCOG00606@2157|Archaea,41SRY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_1436534_4	436308.Nmar_0777	2.185e-41	154.0	COG1828@1|root,arCOG04462@2157|Archaea,41STY@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
CMS3_k127_1436534_7	1229909.NSED_05370	1.145e-06	51.0	arCOG10955@1|root,arCOG10955@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1436534_2	436308.Nmar_0775	6.131e-71	242.0	arCOG08712@1|root,arCOG08712@2157|Archaea,41SU6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1436534_0	436308.Nmar_0774	4.784e-130	419.0	COG0805@1|root,arCOG01919@2157|Archaea,41S69@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS3_k127_1436534_6	436308.Nmar_0773	2.314e-24	104.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_144324_2	436308.Nmar_0872	5.809e-121	391.0	COG1759@1|root,arCOG04346@2157|Archaea,41SBR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
CMS3_k127_144324_4	1229909.NSED_04885	7.516e-22	96.0	arCOG11517@1|root,arCOG11517@2157|Archaea,41TAE@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_144324_0	436308.Nmar_0871	8.898e-253	782.0	COG0017@1|root,arCOG00406@2157|Archaea,41SBT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	-	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_144324_3	436308.Nmar_0870	6.838e-37	140.0	COG0721@1|root,arCOG02726@2157|Archaea,41TB1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	-
CMS3_k127_144324_1	1229909.NSED_04855	2.379e-221	690.0	COG0154@1|root,arCOG01717@2157|Archaea,41SCW@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS3_k127_16256_3	436308.Nmar_1377	0.0008282	42.0	COG0582@1|root,arCOG01245@2157|Archaea	2157|Archaea	L	integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
CMS3_k127_16256_1	1229909.NSED_05380	1.28e-44	162.0	COG0760@1|root,arCOG07441@2157|Archaea,41SSK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
CMS3_k127_16256_2	436308.Nmar_0943	3.824e-33	130.0	arCOG11285@1|root,arCOG11285@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_16256_0	436308.Nmar_0944	2.161e-163	516.0	COG1111@1|root,arCOG00872@2157|Archaea	2157|Archaea	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K03703,ko:K10896	ko03420,ko03460,map03420,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C,ResIII
CMS3_k127_168422_7	436308.Nmar_0774	8.719e-27	109.0	COG0805@1|root,arCOG01919@2157|Archaea,41S69@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS3_k127_168422_8	436308.Nmar_0773	3.176e-24	103.0	COG1826@1|root,arCOG02694@2157|Archaea,41T8C@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_168422_6	436308.Nmar_0772	5.86e-36	141.0	arCOG08713@1|root,arCOG08713@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_168422_2	1229909.NSED_04290	1.66e-103	338.0	COG0163@1|root,arCOG01703@2157|Archaea,41SHU@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CMS3_k127_168422_0	436308.Nmar_0770	1.19e-211	660.0	COG1759@1|root,arCOG04346@2157|Archaea,41S79@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Domain of unknown function (DUF1297)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
CMS3_k127_168422_5	1229909.NSED_04280	3.744e-36	138.0	arCOG07555@1|root,arCOG07555@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_168422_1	1229909.NSED_02115	6.706e-156	499.0	COG1503@1|root,arCOG01742@2157|Archaea	1229909.NSED_02115|-	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
CMS3_k127_168422_4	1229909.NSED_01080	4.046e-43	164.0	COG0317@1|root,arCOG06870@2157|Archaea	2157|Archaea	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
CMS3_k127_168422_3	1229909.NSED_04255	1.491e-46	168.0	COG1259@1|root,arCOG01759@2157|Archaea,41SQI@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS3_k127_1794913_0	436308.Nmar_1392	1.375e-120	391.0	COG0513@1|root,arCOG00078@2157|Archaea,41SM2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
CMS3_k127_1794913_1	436308.Nmar_1393	6.401e-97	320.0	COG0164@1|root,arCOG04121@2157|Archaea,41SK9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS3_k127_1794913_2	436308.Nmar_1394	5.515e-45	165.0	COG1867@1|root,arCOG01219@2157|Archaea,41SAG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family	-	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
CMS3_k127_1880368_0	436308.Nmar_1457	6.649e-159	507.0	arCOG01778@1|root,arCOG01778@2157|Archaea,41SXW@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_1880368_1	330214.NIDE2792	2.485e-75	270.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	NHL
CMS3_k127_1880368_2	1229909.NSED_06250	6.282e-12	67.0	arCOG10955@1|root,arCOG10955@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1880368_3	1229909.NSED_00535	3.855e-09	68.0	arCOG08777@1|root,arCOG08777@2157|Archaea	1229909.NSED_00535|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1936956_2	1229909.NSED_08175	3.868e-98	323.0	arCOG08639@1|root,arCOG08639@2157|Archaea,41SP8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1936956_1	1229909.NSED_08170	1.652e-123	396.0	arCOG08638@1|root,arCOG08638@2157|Archaea,41T08@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_1936956_0	436308.Nmar_1482	0.0	1373.0	COG1048@1|root,arCOG01697@2157|Archaea,41SE6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS3_k127_2013803_1	1229909.NSED_03430	7.921e-168	529.0	COG0155@1|root,arCOG02055@2157|Archaea,41S5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Sulfite reductase	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS3_k127_2013803_2	1229909.NSED_03435	6.415e-167	526.0	COG1635@1|root,arCOG00574@2157|Archaea,41SDJ@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	-	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	Thi4
CMS3_k127_2013803_3	436308.Nmar_0677	7.918e-87	293.0	arCOG04668@1|root,arCOG04668@2157|Archaea,41SMD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2013803_0	436308.Nmar_0672	9.461e-193	603.0	COG0492@1|root,arCOG01296@2157|Archaea,41S97@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_2148047_1	436308.Nmar_0008	3.088e-97	320.0	COG1252@1|root,arCOG01067@2157|Archaea	2157|Archaea	C	COG1252 NADH dehydrogenase, FAD-containing subunit	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_2148047_0	1229909.NSED_09680	4.227e-109	356.0	arCOG01806@1|root,arCOG01806@2157|Archaea,41T2B@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2148047_2	1229909.NSED_09685	1.969e-77	261.0	COG0071@1|root,arCOG01833@2157|Archaea,41SPJ@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS3_k127_2152103_2	436308.Nmar_0938	5.549e-121	394.0	COG1575@1|root,arCOG00480@2157|Archaea,41S8H@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiA prenyltransferase	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS3_k127_2152103_0	436308.Nmar_0937	1.781e-178	564.0	COG0667@1|root,arCOG01623@2157|Archaea,41SA6@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_2152103_6	1229909.NSED_05235	4.073e-58	204.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2152103_7	1229909.NSED_04760	1.15e-55	206.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
CMS3_k127_2152103_9	1229909.NSED_04815	1.525e-29	122.0	COG0745@1|root,arCOG02595@2157|Archaea,41T9R@651137|Thaumarchaeota	651137|Thaumarchaeota	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_2152103_3	1229909.NSED_04820	3.474e-102	344.0	COG0642@1|root,arCOG02362@1|root,arCOG02358@2157|Archaea,arCOG02362@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
CMS3_k127_2152103_11	1229909.NSED_05225	2.851e-19	87.0	arCOG04508@1|root,arCOG04508@2157|Archaea,41SVW@651137|Thaumarchaeota	651137|Thaumarchaeota	P	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CMS3_k127_2152103_1	436308.Nmar_0935	4.867e-121	396.0	COG0367@1|root,arCOG00071@2157|Archaea,41SMA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
CMS3_k127_2152103_4	1229909.NSED_05215	3.106e-78	263.0	COG2522@1|root,arCOG00017@2157|Archaea,41SJZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transcriptional regulator	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_2152103_10	436308.Nmar_0933	1e-28	117.0	COG1581@1|root,arCOG01753@2157|Archaea,41TA9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Alba	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
CMS3_k127_2152103_5	436308.Nmar_0932	7.816e-78	265.0	COG1758@1|root,arCOG01268@2157|Archaea,41ST9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	-	ko:K03014	ko00230,ko00240,ko01100,ko03020,ko04623,ko05016,ko05169,map00230,map00240,map01100,map03020,map04623,map05016,map05169	M00180,M00181,M00182	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS3_k127_2152103_8	1229909.NSED_05200	4.157e-33	134.0	COG2164@1|root,arCOG04488@2157|Archaea,41STM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
CMS3_k127_2184434_0	436308.Nmar_1455	2.192e-117	379.0	COG0015@1|root,arCOG01747@2157|Archaea,41SD1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	adenylosuccinate lyase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS3_k127_2184434_1	436308.Nmar_0587	5.328e-37	142.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
CMS3_k127_2184434_2	1229909.NSED_06370	1.432e-33	133.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SQT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_2184434_3	1229909.NSED_05825	0.0005518	50.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2249965_0	1229909.NSED_03575	1.027e-89	297.0	COG2519@1|root,arCOG00978@2157|Archaea,41SEF@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
CMS3_k127_2249965_1	436308.Nmar_0749	6.764e-56	201.0	arCOG10540@1|root,arCOG10540@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2249965_4	436308.Nmar_0918	7.378e-19	94.0	COG3794@1|root,arCOG02926@2157|Archaea,41T8E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_2249965_2	436308.Nmar_0754	1.928e-24	115.0	COG1196@1|root,arCOG00371@2157|Archaea	2157|Archaea	D	Required for chromosome condensation and partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2249965_5	436308.Nmar_0707	1.652e-08	56.0	COG2201@1|root,arCOG02382@2157|Archaea	2157|Archaea	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CMS3_k127_225721_3	436308.Nmar_1408	8.775e-32	125.0	COG1389@1|root,arCOG01165@2157|Archaea,41SJ2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
CMS3_k127_225721_0	1229909.NSED_07730	3.462e-233	722.0	COG1697@1|root,arCOG04143@2157|Archaea,41SQF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
CMS3_k127_225721_1	436308.Nmar_1406	1.182e-90	300.0	COG0071@1|root,arCOG01833@2157|Archaea	2157|Archaea	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_225721_4	1229909.NSED_07615	1.993e-26	109.0	arCOG08701@1|root,arCOG08701@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_225721_2	436308.Nmar_1404	1.373e-48	175.0	arCOG08702@1|root,arCOG08702@2157|Archaea,41ST2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_232229_1	436308.Nmar_0223	5.757e-119	387.0	COG0788@1|root,arCOG02826@2157|Archaea,41S78@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Formyl transferase	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT_6,Formyl_trans_N
CMS3_k127_232229_0	436308.Nmar_0224	5.356e-225	704.0	COG1109@1|root,arCOG00767@2157|Archaea,41S74@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the phosphohexose mutase family	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_232229_2	1229909.NSED_00950	1.435e-71	242.0	COG1358@1|root,arCOG01751@2157|Archaea,41SMS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	-	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
CMS3_k127_236086_1	436308.Nmar_1038	4.367e-117	378.0	COG1392@1|root,arCOG02640@2157|Archaea,41SGI@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CMS3_k127_236086_2	436308.Nmar_1039	3.883e-100	328.0	COG1676@1|root,arCOG01701@2157|Archaea,41SHW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
CMS3_k127_236086_4	436308.Nmar_1041	2.1e-56	198.0	arCOG08726@1|root,arCOG08726@2157|Archaea,41STN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_236086_5	1229909.NSED_06125	5.336e-35	134.0	arCOG08727@1|root,arCOG08727@2157|Archaea,41T57@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_236086_0	1229909.NSED_06130	2e-322	993.0	COG1028@1|root,arCOG01259@2157|Archaea,41S7V@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_236086_3	1229909.NSED_06135	7.385e-73	247.0	arCOG10570@1|root,arCOG10570@2157|Archaea,41T75@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2379298_3	1229909.NSED_03225	6.721e-41	151.0	COG0391@1|root,arCOG04395@2157|Archaea,41SCH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
CMS3_k127_2379298_1	1229909.NSED_03220	9.962e-95	314.0	COG1920@1|root,arCOG04472@2157|Archaea,41SPV@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Guanylyl transferase CofC like	-	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
CMS3_k127_2379298_0	1229909.NSED_03215	2.465e-187	586.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_2379298_2	1131266.ARWQ01000006_gene246	1.706e-54	196.0	arCOG08741@1|root,arCOG08741@2157|Archaea,41SWQ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_2388274_1	1229909.NSED_09935	5.595e-119	384.0	COG5491@1|root,arCOG00452@2157|Archaea,41SJ3@651137|Thaumarchaeota	651137|Thaumarchaeota	D	conserved protein implicated in secretion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2388274_0	436308.Nmar_0063	3.665e-240	745.0	COG0423@1|root,arCOG00405@2157|Archaea,41S8S@651137|Thaumarchaeota	651137|Thaumarchaeota	J	synthetase (class II)	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS3_k127_2483995_2	1229909.NSED_04135	7.974e-10	59.0	COG1518@1|root,arCOG01452@2157|Archaea,41SYS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	-	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
CMS3_k127_2483995_0	1229909.NSED_06255	8.312e-186	584.0	COG0473@1|root,arCOG01163@2157|Archaea,41SAA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS3_k127_2483995_1	436308.Nmar_1070	3.547e-12	66.0	COG0119@1|root,arCOG02092@2157|Archaea,41SBX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS3_k127_2789994_13	1229909.NSED_04760	1.833e-13	76.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
CMS3_k127_2789994_10	1229909.NSED_07370	1.181e-35	136.0	COG1522@1|root,arCOG01117@2157|Archaea	1229909.NSED_07370|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2789994_12	1229909.NSED_00840	2.358e-24	113.0	arCOG10597@1|root,arCOG10597@2157|Archaea	1229909.NSED_00840|-	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2789994_1	436308.Nmar_0409	5.861e-225	702.0	COG0579@1|root,arCOG00754@2157|Archaea,41SXA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
CMS3_k127_2789994_9	1229909.NSED_02130	1.954e-38	145.0	arCOG08666@1|root,arCOG08666@2157|Archaea,41SVR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2789994_2	1229909.NSED_02140	2.622e-156	499.0	COG1052@1|root,arCOG01755@2157|Archaea,41T1D@651137|Thaumarchaeota	651137|Thaumarchaeota	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS3_k127_2789994_0	1229909.NSED_02150	0.0	1013.0	COG0674@1|root,arCOG01606@2157|Archaea,41S60@651137|Thaumarchaeota	651137|Thaumarchaeota	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS3_k127_2789994_4	273057.SSO2816	6.54e-118	387.0	COG1013@1|root,arCOG01599@2157|Archaea,2XPQG@28889|Crenarchaeota	28889|Crenarchaeota	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
CMS3_k127_2789994_6	1229909.NSED_02160	9.715e-79	264.0	arCOG08664@1|root,arCOG08664@2157|Archaea,41SKM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2789994_7	1229909.NSED_02165	2.001e-77	262.0	arCOG08663@1|root,arCOG08663@2157|Archaea,41SR2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2789994_8	436308.Nmar_0417	2.534e-52	186.0	arCOG10524@1|root,arCOG10524@2157|Archaea,41SVP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2789994_5	436308.Nmar_0418	1.624e-104	341.0	arCOG04033@1|root,arCOG04033@2157|Archaea,41SM5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2789994_3	436308.Nmar_0419	1.624e-118	385.0	COG1478@1|root,arCOG02714@2157|Archaea,41SHA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
CMS3_k127_28712_17	1229909.NSED_01175	1.718e-41	153.0	COG1581@1|root,arCOG01753@2157|Archaea,41SQ4@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
CMS3_k127_28712_6	436308.Nmar_0256	5.88e-170	535.0	COG2513@1|root,arCOG00581@2157|Archaea,41SEN@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
CMS3_k127_28712_10	1229909.NSED_01185	2.235e-82	276.0	COG1695@1|root,arCOG00002@2157|Archaea,41SN8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS3_k127_28712_0	1229909.NSED_01190	0.0	1060.0	COG1053@1|root,arCOG00571@2157|Archaea,41SAM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	fumarate reductase flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS3_k127_28712_11	436308.Nmar_0259	6.675e-77	258.0	COG2009@1|root,arCOG02244@2157|Archaea,41SKZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS3_k127_28712_14	1229909.NSED_01200	4.442e-58	203.0	COG2142@1|root,arCOG04162@2157|Archaea,41SRA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS3_k127_28712_7	436308.Nmar_0261	5.74e-147	467.0	COG0479@1|root,arCOG00962@2157|Archaea,41SAW@651137|Thaumarchaeota	651137|Thaumarchaeota	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
CMS3_k127_28712_12	436308.Nmar_0262	1.52e-66	227.0	COG2151@1|root,arCOG01845@2157|Archaea,41SQV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS3_k127_28712_1	1229909.NSED_01215	3.594e-240	749.0	COG0165@1|root,arCOG01748@2157|Archaea,41S6A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS3_k127_28712_16	1229909.NSED_07360	1.158e-46	170.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T81@651137|Thaumarchaeota	651137|Thaumarchaeota	S	COG4618 ABC-type protease lipase transport system, ATPase and permease components	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_28712_9	436308.Nmar_1331	1.317e-132	426.0	COG1475@1|root,arCOG01875@2157|Archaea	2157|Archaea	K	PFAM ParB domain protein nuclease	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_28712_21	351160.RCIX2474	3.836e-09	67.0	arCOG06717@1|root,arCOG06717@2157|Archaea,2Y1S1@28890|Euryarchaeota,2NA4U@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_28712_20	1236973.JCM9157_2253	3.169e-12	76.0	2ERNT@1|root,33J87@2|Bacteria,1VMAP@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_28712_19	6211.A0A068YIY8	1.43e-12	80.0	COG5023@1|root,KOG1374@2759|Eukaryota,38EF0@33154|Opisthokonta,3BAIB@33208|Metazoa,3CSWX@33213|Bilateria	33208|Metazoa	Z	microtubule nucleation	TUBG2	GO:0000003,GO:0000070,GO:0000086,GO:0000166,GO:0000212,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0000922,GO:0000930,GO:0000931,GO:0001882,GO:0001883,GO:0003002,GO:0003006,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005768,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005827,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0005881,GO:0005929,GO:0006810,GO:0006996,GO:0007010,GO:0007017,GO:0007020,GO:0007049,GO:0007051,GO:0007052,GO:0007056,GO:0007057,GO:0007059,GO:0007088,GO:0007097,GO:0007098,GO:0007127,GO:0007143,GO:0007144,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007310,GO:0007312,GO:0007346,GO:0007389,GO:0008150,GO:0008274,GO:0008275,GO:0008608,GO:0009266,GO:0009581,GO:0009582,GO:0009605,GO:0009628,GO:0009794,GO:0009798,GO:0009950,GO:0009953,GO:0009987,GO:0009994,GO:0010389,GO:0010457,GO:0010564,GO:0012505,GO:0015630,GO:0016043,GO:0016048,GO:0017076,GO:0019001,GO:0019953,GO:0021700,GO:0022402,GO:0022406,GO:0022412,GO:0022414,GO:0022607,GO:0030030,GO:0030031,GO:0030154,GO:0031023,GO:0031109,GO:0031252,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032954,GO:0032991,GO:0033043,GO:0034622,GO:0035639,GO:0036064,GO:0036094,GO:0042802,GO:0042995,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044450,GO:0044463,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0045132,GO:0045177,GO:0045995,GO:0046785,GO:0046907,GO:0048285,GO:0048468,GO:0048469,GO:0048477,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051179,GO:0051225,GO:0051234,GO:0051235,GO:0051239,GO:0051258,GO:0051276,GO:0051302,GO:0051304,GO:0051306,GO:0051316,GO:0051321,GO:0051606,GO:0051640,GO:0051641,GO:0051642,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0051657,GO:0051661,GO:0051663,GO:0051704,GO:0051726,GO:0051783,GO:0055037,GO:0060271,GO:0061842,GO:0061982,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070925,GO:0071840,GO:0072687,GO:0090306,GO:0097159,GO:0097367,GO:0097435,GO:0097708,GO:0097711,GO:0097730,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0140013,GO:0140014,GO:0140056,GO:1901265,GO:1901363,GO:1901987,GO:1901990,GO:1902412,GO:1902749,GO:1902850,GO:1903046,GO:1903047,GO:1903436,GO:2000026	-	ko:K10389	ko05165,map05165	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	Tubulin,Tubulin_C
CMS3_k127_28712_13	1229909.NSED_01605	1.04e-60	217.0	arCOG08038@1|root,arCOG10597@1|root,arCOG08038@2157|Archaea,arCOG10597@2157|Archaea,41SZN@651137|Thaumarchaeota	651137|Thaumarchaeota	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_28712_2	1229909.NSED_03925	1.532e-222	698.0	COG5427@1|root,arCOG00563@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS3_k127_28712_4	1229909.NSED_03920	3.826e-208	653.0	COG0463@1|root,arCOG00894@2157|Archaea,41SAS@651137|Thaumarchaeota	651137|Thaumarchaeota	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
CMS3_k127_28712_18	1459636.NTE_00321	2.439e-41	154.0	arCOG11305@1|root,arCOG11305@2157|Archaea,41T7G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_28712_8	436308.Nmar_0268	7.138e-143	456.0	COG0483@1|root,arCOG01349@2157|Archaea,41SIF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS3_k127_28712_5	1229909.NSED_01245	4.935e-197	618.0	arCOG08783@1|root,arCOG08783@2157|Archaea,41SFX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_28712_3	1229909.NSED_01250	1.235e-208	653.0	COG0470@1|root,arCOG00470@2157|Archaea,41S9F@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA
CMS3_k127_28712_15	1229909.NSED_01255	1.179e-47	172.0	arCOG08784@1|root,arCOG08784@2157|Archaea,41SVZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2881477_4	1459636.NTE_03071	4.509e-68	241.0	COG0861@1|root,arCOG09430@2157|Archaea	2157|Archaea	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CMS3_k127_2881477_0	436308.Nmar_1000	1.281e-101	344.0	arCOG11734@1|root,arCOG11734@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2881477_1	1229909.NSED_08135	1.989e-92	312.0	COG0010@1|root,arCOG01700@2157|Archaea,41T23@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS3_k127_2881477_7	1229909.NSED_02085	1.617e-05	50.0	arCOG12097@1|root,arCOG12097@2157|Archaea	1229909.NSED_02085|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2881477_2	243231.GSU1399	2.135e-91	313.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,43SCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS3_k127_2881477_5	436308.Nmar_1002	4.567e-54	192.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2881477_8	751944.HALDL1_01525	0.0001185	49.0	COG3205@1|root,arCOG08188@2157|Archaea,2XZXF@28890|Euryarchaeota,23XIS@183963|Halobacteria	183963|Halobacteria	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
CMS3_k127_2881477_3	1229909.NSED_02125	2.534e-71	251.0	COG0517@1|root,arCOG00601@2157|Archaea	2157|Archaea	C	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2881477_6	436308.Nmar_1098	7.219e-20	89.0	COG0608@1|root,arCOG00424@2157|Archaea,41SE2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
CMS3_k127_2883219_1	436308.Nmar_1492	1.138e-72	248.0	arCOG03272@1|root,arCOG03272@2157|Archaea	436308.Nmar_1492|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2883219_2	1229909.NSED_08205	1.554e-39	148.0	arCOG10585@1|root,arCOG10585@2157|Archaea,41SW6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2883219_0	436308.Nmar_1490	7.595e-177	555.0	COG0180@1|root,arCOG01887@2157|Archaea,41SDK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS3_k127_2922451_1	436308.Nmar_0939	2.184e-59	208.0	COG4911@1|root,arCOG05495@2157|Archaea,41SNJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
CMS3_k127_2922451_0	1229909.NSED_05300	5.28e-105	349.0	COG1378@1|root,arCOG02038@2157|Archaea	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
CMS3_k127_2922451_2	1229909.NSED_05295	2.147e-57	202.0	COG2064@1|root,arCOG01808@2157|Archaea	2157|Archaea	NU	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
CMS3_k127_2952633_0	1229909.NSED_00745	1.323e-146	467.0	COG0107@1|root,arCOG00617@2157|Archaea,41S9A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_2952633_1	1229909.NSED_00740	1.001e-115	376.0	COG0106@1|root,arCOG00618@2157|Archaea,41SIG@651137|Thaumarchaeota	651137|Thaumarchaeota	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_2952633_2	1229909.NSED_00735	1.13e-50	180.0	COG0118@1|root,arCOG00089@2157|Archaea,41SY2@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_2959602_2	1229909.NSED_08320	1.254e-14	74.0	COG1325@1|root,arCOG01042@2157|Archaea,41SWK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA binding	-	-	-	ko:K07581	-	-	-	-	ko00000	-	-	-	RNA_binding
CMS3_k127_2959602_1	436308.Nmar_1512	5.566e-116	374.0	COG1890@1|root,arCOG04186@2157|Archaea,41SM9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS1 family	rps3ae	-	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
CMS3_k127_2959602_0	1229909.NSED_08310	4.747e-208	651.0	COG0172@1|root,arCOG00403@2157|Archaea,41SC9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS3_k127_297747_1	436308.Nmar_0503	4.089e-61	219.0	arCOG12815@1|root,arCOG12815@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_297747_4	1131266.ARWQ01000002_gene437	1.739e-05	51.0	COG1405@1|root,arCOG01981@2157|Archaea,41SYU@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_297747_2	436308.Nmar_0505	6.263e-48	173.0	COG1599@1|root,arCOG01510@2157|Archaea,41SV1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
CMS3_k127_297747_0	436308.Nmar_0506	8.876e-108	351.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41T0Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_297747_3	436308.Nmar_0507	1.743e-16	79.0	COG1418@1|root,arCOG01860@2157|Archaea,41T2N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_2987805_1	1229909.NSED_08915	1.838e-119	386.0	arCOG08793@1|root,arCOG08812@1|root,arCOG08793@2157|Archaea,arCOG08812@2157|Archaea,41T0K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2987805_3	436308.Nmar_1645	7.992e-17	81.0	COG3398@1|root,arCOG02611@2157|Archaea,41T7Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
CMS3_k127_2987805_0	436308.Nmar_1644	3.5e-190	601.0	arCOG08728@1|root,arCOG08728@2157|Archaea,41SW1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_2987805_2	1131266.ARWQ01000009_gene929	6.397e-30	120.0	COG0705@1|root,arCOG01768@2157|Archaea,41SKD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_2993275_4	1229909.NSED_04470	1.207e-66	228.0	COG0185@1|root,arCOG04099@2157|Archaea,41SMH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS3_k127_2993275_2	436308.Nmar_0805	7.295e-85	283.0	COG0091@1|root,arCOG04098@2157|Archaea,41SJ4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS3_k127_2993275_0	1229909.NSED_04460	8.17e-130	418.0	COG0092@1|root,arCOG04097@2157|Archaea,41SIM@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds the lower part of the 30S subunit head	rps3	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS3_k127_2993275_7	1229909.NSED_04455	7.154e-27	110.0	COG0255@1|root,arCOG00785@2157|Archaea,41SV8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uL29 family	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS3_k127_2993275_8	1229909.NSED_04450	2.716e-26	110.0	COG1588@1|root,arCOG00784@2157|Archaea,41TB4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	-	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
CMS3_k127_2993275_5	1229909.NSED_04445	3.99e-53	188.0	COG0186@1|root,arCOG04096@2157|Archaea,41SSH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS3_k127_2993275_3	436308.Nmar_0800	6.656e-78	261.0	COG0093@1|root,arCOG04095@2157|Archaea,41SHG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS3_k127_2993275_6	1229909.NSED_04435	1.701e-51	186.0	COG0198@1|root,arCOG04094@2157|Archaea,41SSS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L26
CMS3_k127_2993275_1	436308.Nmar_0798	1.14e-121	393.0	COG1471@1|root,arCOG04093@2157|Archaea,41SIE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS4 family	rps4e	-	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
CMS3_k127_3006404_1	436308.Nmar_1457	2.202e-156	499.0	arCOG01778@1|root,arCOG01778@2157|Archaea,41SXW@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS3_k127_3006404_3	1229909.NSED_01005	2.079e-84	282.0	COG0586@1|root,arCOG03117@2157|Archaea,41SQ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_3006404_0	1229909.NSED_04505	3.456e-178	567.0	COG2133@1|root,arCOG02796@2157|Archaea,41T0Q@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_3006404_2	1229909.NSED_01015	1.656e-103	340.0	COG1573@1|root,arCOG00905@2157|Archaea	2157|Archaea	L	Uracil-DNA glycosylase	-	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_3006404_4	436308.Nmar_0363	1.582e-47	185.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3017993_3	1229909.NSED_02470	4.128e-141	451.0	COG1587@1|root,arCOG02048@2157|Archaea,41SN2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS3_k127_3017993_2	1229909.NSED_02465	2.313e-148	470.0	COG0007@1|root,arCOG00644@2157|Archaea,41S9J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
CMS3_k127_3017993_1	1229909.NSED_02460	1.365e-170	539.0	COG0181@1|root,arCOG04299@2157|Archaea,41S6Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS3_k127_3017993_0	436308.Nmar_0490	1.715e-251	778.0	COG0001@1|root,arCOG00918@2157|Archaea,41SDE@651137|Thaumarchaeota	651137|Thaumarchaeota	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_3128112_0	436308.Nmar_1628	4.15e-199	623.0	COG0640@1|root,COG1328@1|root,arCOG00734@2157|Archaea,arCOG04889@2157|Archaea,41SBG@651137|Thaumarchaeota	651137|Thaumarchaeota	FK	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,HTH_20,NRDD
CMS3_k127_3128112_1	436308.Nmar_1629	6.813e-28	113.0	arCOG08792@1|root,arCOG08792@2157|Archaea,41SUG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_312887_0	1229909.NSED_07335	2.541e-139	445.0	COG1405@1|root,arCOG01981@2157|Archaea	2157|Archaea	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_312887_3	1229909.NSED_06645	1.426e-06	51.0	arCOG11430@1|root,arCOG11430@2157|Archaea	1229909.NSED_06645|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_312887_1	1229909.NSED_02060	1.19e-68	239.0	arCOG08716@1|root,arCOG08716@2157|Archaea	1229909.NSED_02060|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3142417_3	1229909.NSED_05295	4.514e-84	283.0	COG2064@1|root,arCOG01808@2157|Archaea	2157|Archaea	NU	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
CMS3_k127_3142417_1	1229909.NSED_05290	2.174e-138	445.0	COG2064@1|root,arCOG01808@2157|Archaea	2157|Archaea	NU	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
CMS3_k127_3142417_0	1229909.NSED_05285	7.553e-271	841.0	COG4962@1|root,arCOG01817@2157|Archaea,41T25@651137|Thaumarchaeota	651137|Thaumarchaeota	N	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS3_k127_3142417_2	1229909.NSED_05280	1.152e-90	310.0	arCOG06883@1|root,arCOG06883@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2334,DZR
CMS3_k127_3185821_5	1229909.NSED_09025	1.011e-59	209.0	COG0589@1|root,arCOG02053@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	2.7.13.3	ko:K07646,ko:K20989	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	2.A.21.6	-	-	DUF4118,GAF_3,KdpD,Usp
CMS3_k127_3185821_12	698757.Pogu_1910	6.638e-15	75.0	COG3369@1|root,arCOG01667@2157|Archaea	2157|Archaea	S	Zinc finger CDGSH-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CMS3_k127_3185821_13	1229909.NSED_05370	0.000877	44.0	arCOG10955@1|root,arCOG10955@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3185821_8	436308.Nmar_0743	7.866e-36	138.0	COG0011@1|root,arCOG04373@2157|Archaea,41T99@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
CMS3_k127_3185821_0	1229909.NSED_04040	1.43e-200	628.0	COG1060@1|root,arCOG00656@2157|Archaea,41SEG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
CMS3_k127_3185821_4	1229909.NSED_04030	3.644e-61	214.0	arCOG03048@1|root,arCOG03048@2157|Archaea,41T7I@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
CMS3_k127_3185821_7	436308.Nmar_1129	3.66e-51	191.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_3185821_2	436308.Nmar_0598	4.918e-93	308.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
CMS3_k127_3185821_11	1131266.ARWQ01000002_gene615	3.136e-25	106.0	COG0457@1|root,arCOG03032@2157|Archaea,41T66@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
CMS3_k127_3185821_3	436308.Nmar_0738	2.028e-65	226.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
CMS3_k127_3185821_6	1229909.NSED_04015	1.026e-57	207.0	COG0484@1|root,arCOG02846@2157|Archaea,41T68@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
CMS3_k127_3185821_9	436308.Nmar_0736	1.197e-34	136.0	arCOG08802@1|root,arCOG08802@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3185821_10	1229909.NSED_04995	4.028e-32	127.0	arCOG10559@1|root,arCOG10559@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3185821_1	1229909.NSED_03795	1.879e-131	424.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3191598_5	1286171.EAL2_c03300	9.129e-08	67.0	COG3391@1|root,COG3391@2|Bacteria,1VCN6@1239|Firmicutes	1239|Firmicutes	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS3_k127_3191598_3	456442.Mboo_1601	3.388e-09	72.0	COG3291@1|root,COG3391@1|root,arCOG02510@2157|Archaea,arCOG03563@2157|Archaea	2157|Archaea	P	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,NHL,PKD
CMS3_k127_3191598_4	283942.IL1851	4.934e-09	63.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,1S67R@1236|Gammaproteobacteria,2QGEY@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	cheY-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_3191598_1	1229909.NSED_05505	2.028e-74	260.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_3191598_2	1459636.NTE_00361	6.562e-28	119.0	arCOG08805@1|root,arCOG08805@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3191598_0	1380384.JADN01000006_gene2580	6.144e-92	308.0	COG1878@1|root,COG1878@2|Bacteria,4NFYB@976|Bacteroidetes,1IIVK@117743|Flavobacteriia	976|Bacteroidetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS3_k127_3191598_6	1459636.NTE_00251	1.965e-05	48.0	COG0662@1|root,arCOG03003@2157|Archaea	2157|Archaea	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2,Cupin_3
CMS3_k127_323494_1	436308.Nmar_0373	8.689e-77	259.0	arCOG08745@1|root,arCOG08745@2157|Archaea,41SU1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_323494_0	1229909.NSED_01805	4.754e-220	685.0	COG0013@1|root,arCOG01255@2157|Archaea,41SBJ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS3_k127_3240333_1	436308.Nmar_0921	1.165e-116	377.0	COG0061@1|root,COG0640@1|root,arCOG00394@2157|Archaea,arCOG01348@2157|Archaea,41SEC@651137|Thaumarchaeota	651137|Thaumarchaeota	HK	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS3_k127_3240333_0	1229909.NSED_05135	6.632e-166	524.0	COG0504@1|root,arCOG00063@2157|Archaea,41S7G@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS3_k127_3291305_0	436308.Nmar_0214	6.97e-118	381.0	COG0044@1|root,arCOG00689@2157|Archaea,41S8A@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
CMS3_k127_3291305_3	436308.Nmar_0218	4.693e-104	341.0	COG0120@1|root,arCOG01122@2157|Archaea,41SJE@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Ribose 5-phosphate isomerase	-	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS3_k127_3291305_1	436308.Nmar_0219	4.156e-108	358.0	arCOG08635@1|root,arCOG08635@2157|Archaea,41T54@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3291305_5	1229909.NSED_00925	3.358e-32	124.0	COG2126@1|root,arCOG04126@2157|Archaea,41T9V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl37e	-	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
CMS3_k127_3291305_4	1229909.NSED_00930	1.539e-37	141.0	COG1958@1|root,arCOG00998@2157|Archaea,41SU9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
CMS3_k127_3291305_2	1229909.NSED_00935	2.242e-107	353.0	COG1402@1|root,arCOG04536@2157|Archaea,41SNC@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS3_k127_3291305_6	436308.Nmar_0223	6.538e-18	83.0	COG0788@1|root,arCOG02826@2157|Archaea,41S78@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Formyl transferase	-	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT_6,Formyl_trans_N
CMS3_k127_3309672_1	436308.Nmar_0964	5.208e-245	759.0	COG0499@1|root,arCOG04137@2157|Archaea,41S9I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	S-adenosyl-L-homocysteine hydrolase, NAD binding domain	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS3_k127_3309672_0	1229909.NSED_05545	4.35e-322	989.0	COG0143@1|root,arCOG00810@2157|Archaea,41SAF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
CMS3_k127_3309672_2	436308.Nmar_0962	1.705e-119	387.0	arCOG07550@1|root,arCOG07550@2157|Archaea,41SXF@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF726
CMS3_k127_3309672_3	391612.CY0110_08276	4.549e-38	162.0	COG2304@1|root,COG3210@1|root,COG2304@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,DUF4214,HemolysinCabind,SdrD_B,VWA,VWA_2
CMS3_k127_3338908_0	436308.Nmar_1481	4.783e-150	477.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_343851_4	438753.AZC_2591	0.0006879	45.0	COG3157@1|root,COG3157@2|Bacteria,1RCKW@1224|Proteobacteria,2U61Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
CMS3_k127_343851_3	756272.Plabr_1743	1.143e-22	104.0	COG3157@1|root,COG3157@2|Bacteria,2J0G0@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM type VI secretion system effector, Hcp1 family	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
CMS3_k127_343851_1	436308.Nmar_0823	9.591e-103	339.0	COG0132@1|root,arCOG00100@2157|Archaea,41SQX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS3_k127_343851_2	436308.Nmar_0827	3.688e-56	201.0	arCOG08721@1|root,arCOG08721@2157|Archaea,41SRS@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_343851_0	436308.Nmar_0828	9.52e-156	494.0	COG3425@1|root,arCOG01767@2157|Archaea,41SAQ@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Hydroxymethylglutaryl-coenzyme A synthase N terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG_CoA_synt_C,HMG_CoA_synt_N
CMS3_k127_354924_3	273116.14325632	9.287e-26	113.0	COG0842@1|root,arCOG01467@2157|Archaea,2XT3B@28890|Euryarchaeota,2429G@183967|Thermoplasmata	183967|Thermoplasmata	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_354924_1	436308.Nmar_0090	5.609e-155	493.0	COG1131@1|root,arCOG00194@2157|Archaea,41TB8@651137|Thaumarchaeota	651137|Thaumarchaeota	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS3_k127_354924_6	1089547.KB913013_gene710	0.0001071	44.0	2CFT1@1|root,32WXV@2|Bacteria,4NTST@976|Bacteroidetes,47X5U@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_354924_0	436308.Nmar_1325	3.667e-193	613.0	arCOG07561@1|root,arCOG07561@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3,VWA
CMS3_k127_354924_2	1131266.ARWQ01000029_gene982	1.745e-104	358.0	arCOG08793@1|root,arCOG08793@2157|Archaea,41TBC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_354924_5	1236973.JCM9157_2253	1.974e-14	83.0	2ERNT@1|root,33J87@2|Bacteria,1VMAP@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_354924_4	1229909.NSED_00145	1.733e-19	89.0	COG1599@1|root,arCOG01510@2157|Archaea,41S9M@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
CMS3_k127_3591023_2	1229909.NSED_07320	1.3e-240	746.0	COG3569@1|root,arCOG08649@2157|Archaea,41SDH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA Topoisomerase I (eukaryota)	-	-	5.99.1.2	ko:K03163	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topo_C_assoc,Topoisom_I,Topoisom_I_N
CMS3_k127_3591023_5	1229909.NSED_07315	1.298e-141	454.0	COG1028@1|root,arCOG01259@2157|Archaea,41SGH@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_3591023_0	1229909.NSED_07310	0.0	1437.0	COG1205@1|root,arCOG08693@1|root,arCOG00555@2157|Archaea,arCOG08693@2157|Archaea,41SZS@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD DEAH box helicase	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
CMS3_k127_3591023_4	436308.Nmar_1319	2.87e-150	477.0	COG0863@1|root,arCOG00115@2157|Archaea,41SZP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA methylase	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS3_k127_3591023_12	436308.Nmar_1318	9.59e-40	150.0	COG1826@1|root,arCOG02694@2157|Archaea,41SRR@651137|Thaumarchaeota	651137|Thaumarchaeota	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS3_k127_3591023_3	436308.Nmar_1316	4.483e-206	646.0	COG0477@1|root,arCOG00130@2157|Archaea,41T0X@651137|Thaumarchaeota	651137|Thaumarchaeota	G	major facilitator superfamily	-	-	-	ko:K08153,ko:K08221	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8,2.A.1.32	-	-	MFS_1
CMS3_k127_3591023_7	436308.Nmar_1315	5.507e-129	414.0	COG2226@1|root,arCOG04348@2157|Archaea,41SGQ@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_3591023_6	1229909.NSED_07280	2.288e-130	419.0	COG0638@1|root,arCOG00971@2157|Archaea,41SYA@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Proteasome endopeptidase complex	-	-	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
CMS3_k127_3591023_10	436308.Nmar_1313	1.477e-57	202.0	COG0640@1|root,arCOG00731@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS3_k127_3591023_1	436308.Nmar_1312	5.392e-256	793.0	COG0334@1|root,arCOG01352@2157|Archaea,41S7T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS3_k127_3591023_11	1229909.NSED_07265	2.178e-46	169.0	COG1658@1|root,arCOG01486@2157|Archaea,41SU4@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Toprim domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3591023_8	436308.Nmar_1310	7.737e-111	361.0	COG0518@1|root,arCOG00090@2157|Archaea,41T3Z@651137|Thaumarchaeota	651137|Thaumarchaeota	F	glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase
CMS3_k127_3591023_9	1229909.NSED_09505	3.6e-63	222.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
CMS3_k127_361649_0	436308.Nmar_1085	2.908e-230	715.0	COG0458@1|root,arCOG01594@2157|Archaea,41SBF@651137|Thaumarchaeota	651137|Thaumarchaeota	E	MGS-like domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS3_k127_361649_1	1229909.NSED_06310	5.263e-119	386.0	COG1407@1|root,arCOG01150@2157|Archaea,41SJB@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Calcineurin-like phosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
CMS3_k127_361649_2	1229909.NSED_06305	1.658e-42	157.0	COG5431@1|root,arCOG01120@2157|Archaea,41SW3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3629870_0	1229909.NSED_03210	6.792e-93	308.0	arCOG08741@1|root,arCOG08741@2157|Archaea,41SWQ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS3_k127_3629870_1	1131266.ARWQ01000001_gene1233	5.431e-78	273.0	arCOG08728@1|root,arCOG14091@1|root,arCOG08728@2157|Archaea,arCOG14091@2157|Archaea,41T6X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3735921_4	436308.Nmar_1467	7.134e-64	230.0	COG1525@1|root,arCOG03192@2157|Archaea	2157|Archaea	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS3_k127_3735921_0	1229909.NSED_01760	1.306e-116	377.0	COG2013@1|root,arCOG01907@2157|Archaea,41T1Q@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
CMS3_k127_3735921_3	1163730.FFONT_0008	5.515e-66	233.0	COG0730@1|root,arCOG02050@2157|Archaea,2XQGT@28889|Crenarchaeota	28889|Crenarchaeota	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_3735921_1	1341151.ASZU01000014_gene2149	9.684e-71	257.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,27B4H@186824|Thermoactinomycetaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS3_k127_3735921_7	1459636.NTE_00909	8.6e-10	66.0	arCOG08805@1|root,arCOG08805@2157|Archaea	1459636.NTE_00909|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3735921_5	1229909.NSED_05350	4.43e-28	117.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413,ko:K07662,ko:K07667	ko01503,ko02020,ko02024,ko02030,map01503,map02020,map02024,map02030	M00447,M00454,M00506,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CHASE4,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
CMS3_k127_3735921_2	1131266.ARWQ01000001_gene1118	1.182e-66	235.0	arCOG08638@1|root,arCOG08638@2157|Archaea,41T08@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3823104_9	1229909.NSED_04625	5.846e-16	79.0	COG1545@1|root,arCOG01289@2157|Archaea,41SWD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_3823104_3	1229909.NSED_04615	1.078e-78	266.0	COG1591@1|root,arCOG00919@2157|Archaea,41SQP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
CMS3_k127_3823104_4	1229909.NSED_04610	2.678e-68	234.0	arCOG11395@1|root,arCOG11395@2157|Archaea,41TBH@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3823104_5	1229909.NSED_04605	3.817e-43	159.0	arCOG08697@1|root,arCOG08697@2157|Archaea,41SUN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3823104_7	436308.Nmar_0834	1.824e-30	124.0	arCOG10552@1|root,arCOG10552@2157|Archaea,41T8T@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3823104_0	1229909.NSED_04595	1.053e-263	816.0	COG0498@1|root,arCOG01434@2157|Archaea,41S5N@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_3823104_1	436308.Nmar_0832	1.077e-212	666.0	COG1253@1|root,arCOG00626@2157|Archaea,41T1G@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS3_k127_3823104_2	436308.Nmar_0831	2.859e-198	621.0	COG0057@1|root,arCOG00493@2157|Archaea,41SDF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.59	ko:K00150	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166	R01061,R01063	RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS3_k127_3823104_8	436308.Nmar_1637	9.845e-25	118.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3823104_6	1459636.NTE_01762	9.473e-41	166.0	COG0726@1|root,arCOG02876@2157|Archaea,41T20@651137|Thaumarchaeota	2157|Archaea	G	xylanase chitin deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CHB_HEX_C_1,HYR,Polysacc_deac_1
CMS3_k127_3850311_1	436308.Nmar_1598	5.102e-39	148.0	arCOG08790@1|root,arCOG08790@2157|Archaea,41SWN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3850311_0	436308.Nmar_1597	2.749e-241	750.0	COG0043@1|root,arCOG01671@2157|Archaea,41SEQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
CMS3_k127_3850311_3	1131266.ARWQ01000010_gene31	1.361e-20	96.0	arCOG11448@1|root,arCOG11448@2157|Archaea,41T9T@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3850311_2	1229909.NSED_08640	4.067e-31	123.0	COG1607@1|root,arCOG00773@2157|Archaea,41T2J@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS3_k127_385948_9	1229909.NSED_09505	1.248e-35	139.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
CMS3_k127_385948_3	1365176.N186_01385	7.627e-144	472.0	COG0213@1|root,arCOG02013@2157|Archaea,2XPZT@28889|Crenarchaeota	28889|Crenarchaeota	F	Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO	-	-	2.4.2.57	ko:K18931	-	-	R10836,R10837,R10838	RC00063	ko00000,ko01000	-	-	-	CDC48_N,Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS3_k127_385948_11	436308.Nmar_0674	3.238e-22	101.0	COG0589@1|root,arCOG02053@2157|Archaea,41TB2@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_385948_12	1229909.NSED_02910	1.868e-15	78.0	arCOG14076@1|root,arCOG14076@2157|Archaea	1229909.NSED_02910|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_385948_8	396588.Tgr7_0813	1.516e-43	164.0	COG0778@1|root,COG0778@2|Bacteria,1NMNU@1224|Proteobacteria	1224|Proteobacteria	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_385948_0	436308.Nmar_1309	0.0	1307.0	COG1042@1|root,arCOG01338@2157|Archaea,arCOG01340@2157|Archaea,41S7I@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K18594	ko00720,ko01120,map00720,map01120	-	R03157	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CMS3_k127_385948_2	1229909.NSED_07245	1.84e-150	477.0	COG1024@1|root,arCOG00239@2157|Archaea,41SH7@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.116	ko:K15019	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00375	R03045	RC00834	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS3_k127_385948_5	1229909.NSED_07230	1.623e-87	292.0	arCOG08805@1|root,arCOG08805@2157|Archaea,41T3X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_385948_10	1229909.NSED_07225	1.695e-35	139.0	COG0517@1|root,arCOG00606@2157|Archaea	2157|Archaea	I	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_385948_7	436308.Nmar_1303	1.067e-64	222.0	COG0316@1|root,arCOG04560@2157|Archaea,41SKH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Iron-sulfur cluster assembly accessory protein	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS3_k127_385948_1	1229909.NSED_07215	4.567e-209	653.0	COG0358@1|root,arCOG04281@2157|Archaea,41S75@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA primase	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
CMS3_k127_385948_4	1229909.NSED_07210	4.168e-106	347.0	COG1339@1|root,arCOG01904@2157|Archaea,41SG9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Domain of unknown function DUF120	-	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase
CMS3_k127_385948_6	436308.Nmar_1298	3.743e-75	256.0	COG0615@1|root,arCOG01222@2157|Archaea,41SPR@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Cytidylyltransferase-like	-	-	2.7.7.2,2.7.7.39	ko:K00980,ko:K14656	ko00564,ko00740,ko01100,ko01110,map00564,map00740,map01100,map01110	-	R00161,R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
CMS3_k127_3877671_3	1229909.NSED_04250	3.207e-53	190.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
CMS3_k127_3877671_1	1229909.NSED_04245	1.022e-128	415.0	arCOG08714@1|root,arCOG08714@2157|Archaea,41SPW@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_6	1229909.NSED_04240	3.231e-35	137.0	arCOG10546@1|root,arCOG10546@2157|Archaea,41SRD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_10	436308.Nmar_0761	4.085e-16	81.0	arCOG10545@1|root,arCOG10545@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_7	1131266.ARWQ01000002_gene601	9.998e-32	126.0	COG1656@1|root,arCOG04290@2157|Archaea,41T6F@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_8	1229909.NSED_04200	8.343e-31	124.0	arCOG11446@1|root,arCOG11446@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_2	1229909.NSED_04195	3.182e-59	207.0	arCOG05565@1|root,arCOG05565@2157|Archaea,41T3I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_5	1229909.NSED_04180	1.292e-40	160.0	COG3794@1|root,arCOG02926@2157|Archaea,41T8E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_3877671_11	436308.Nmar_0753	7.863e-13	71.0	arCOG10544@1|root,arCOG10544@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_4	436308.Nmar_0752	8.529e-47	171.0	arCOG10543@1|root,arCOG10543@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_12	1229909.NSED_04160	2.178e-06	49.0	arCOG10542@1|root,arCOG10542@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_14	436308.Nmar_0751	0.0001147	45.0	arCOG10542@1|root,arCOG10542@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_9	436308.Nmar_0750	1.638e-21	95.0	arCOG10541@1|root,arCOG10541@2157|Archaea,41T8Z@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3877671_13	1131266.ARWQ01000002_gene437	1.226e-05	51.0	COG1405@1|root,arCOG01981@2157|Archaea,41SYU@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_3877671_0	436308.Nmar_0748	0.0	1332.0	COG0480@1|root,arCOG01559@2157|Archaea,41S9B@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS3_k127_3949094_5	1229909.NSED_00050	2.447e-62	216.0	COG2125@1|root,arCOG01946@2157|Archaea,41SPC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	-	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
CMS3_k127_3949094_0	1229909.NSED_00055	3.006e-243	754.0	COG3276@1|root,arCOG01563@2157|Archaea,41S80@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Initiation factor	-	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,eIF2_C
CMS3_k127_3949094_4	436308.Nmar_0074	1.03e-64	224.0	COG1881@1|root,arCOG04702@2157|Archaea,41T4M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS3_k127_3949094_6	1229909.NSED_00075	2.205e-24	104.0	COG2260@1|root,arCOG00906@2157|Archaea,41SUI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
CMS3_k127_3949094_2	1229909.NSED_00080	4.333e-135	434.0	COG1093@1|root,arCOG04107@2157|Archaea,41SHY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor 2, alpha subunit	-	-	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
CMS3_k127_3949094_3	1229909.NSED_00085	2.9e-85	286.0	COG2109@1|root,arCOG04678@2157|Archaea,41SFP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	ATP corrinoid adenosyltransferase	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
CMS3_k127_3949094_1	436308.Nmar_0079	6.788e-184	583.0	COG1797@1|root,arCOG00106@2157|Archaea,41SBP@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
CMS3_k127_3957130_2	1229909.NSED_08325	9.858e-70	237.0	COG0644@1|root,arCOG00570@2157|Archaea,41SBB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3957130_0	1229909.NSED_08330	1.488e-145	463.0	COG0714@1|root,arCOG00441@2157|Archaea,41SDZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5
CMS3_k127_3957130_1	1229909.NSED_08335	4.434e-116	376.0	COG2304@1|root,arCOG02900@2157|Archaea,41SDY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3971781_7	436308.Nmar_1329	3.578e-25	109.0	arCOG08796@1|root,arCOG08796@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3971781_2	1229909.NSED_04960	6.233e-93	308.0	arCOG10557@1|root,arCOG10557@2157|Archaea,41T1I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3971781_4	1229909.NSED_04955	3.104e-61	213.0	COG0537@1|root,arCOG00419@2157|Archaea,41SNV@651137|Thaumarchaeota	651137|Thaumarchaeota	F	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_3971781_0	1229909.NSED_04950	3.561e-235	732.0	COG1503@1|root,arCOG01742@2157|Archaea,41SEK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
CMS3_k127_3971781_1	436308.Nmar_0881	4.547e-106	347.0	COG1651@1|root,arCOG02868@2157|Archaea,41T2W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS3_k127_3971781_3	436308.Nmar_0880	7.003e-90	301.0	arCOG02103@1|root,arCOG02103@2157|Archaea,41T51@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF4443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4443
CMS3_k127_3971781_6	436308.Nmar_0879	1.203e-31	124.0	arCOG08746@1|root,arCOG08746@2157|Archaea,41SWA@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Probable cobalt transporter subunit (CbtB)	-	-	-	-	-	-	-	-	-	-	-	-	CbtB
CMS3_k127_3971781_5	436308.Nmar_0878	7.396e-53	188.0	arCOG06353@1|root,arCOG06353@2157|Archaea,41SI1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
CMS3_k127_3996799_2	436308.Nmar_1351	1.052e-06	51.0	arCOG10581@1|root,arCOG10581@2157|Archaea,41T5S@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_3996799_0	436308.Nmar_0886	1e-323	995.0	COG0129@1|root,arCOG04045@2157|Archaea,41SD0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS3_k127_4065273_2	1229909.NSED_09055	2.196e-19	91.0	arCOG10411@1|root,arCOG10411@2157|Archaea,41T7X@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4065273_0	436308.Nmar_1700	2.335e-173	549.0	COG1527@1|root,arCOG02459@2157|Archaea,41T18@651137|Thaumarchaeota	651137|Thaumarchaeota	C	ATP synthase (C/AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
CMS3_k127_4065273_1	1229909.NSED_09045	3.077e-59	207.0	arCOG08770@1|root,arCOG08770@2157|Archaea,41T2S@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4094348_3	1229909.NSED_05135	1.178e-42	156.0	COG0504@1|root,arCOG00063@2157|Archaea,41S7G@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS3_k127_4094348_2	633697.EubceDRAFT1_1049	4.409e-53	196.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,25VB7@186806|Eubacteriaceae	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS3_k127_4094348_0	1229909.NSED_05125	2.156e-237	736.0	COG0133@1|root,arCOG01433@2157|Archaea,41S87@651137|Thaumarchaeota	651137|Thaumarchaeota	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_4094348_1	436308.Nmar_0914	1.829e-95	314.0	COG0134@1|root,arCOG01088@2157|Archaea,41SN7@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS3_k127_4104855_1	1229909.NSED_08925	4.469e-17	91.0	arCOG08793@1|root,arCOG08812@1|root,arCOG08793@2157|Archaea,arCOG08812@2157|Archaea,41SXB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4104855_0	530564.Psta_1833	1.56e-35	143.0	COG3157@1|root,COG3157@2|Bacteria,2J1I6@203682|Planctomycetes	203682|Planctomycetes	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
CMS3_k127_421321_3	1229909.NSED_05700	4.388e-52	188.0	COG2236@1|root,arCOG00040@2157|Archaea,41TA1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	phosphoribosyltransferase	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_421321_0	436308.Nmar_0987	4.568e-170	537.0	COG1405@1|root,arCOG01981@2157|Archaea,41SYU@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_421321_1	1229909.NSED_05690	2.107e-169	544.0	COG0457@1|root,COG5549@1|root,arCOG03038@2157|Archaea,arCOG04994@2157|Archaea,41T10@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10,TPR_8
CMS3_k127_421321_4	1229909.NSED_05685	1.43e-23	104.0	arCOG08756@1|root,arCOG08756@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_421321_2	1229909.NSED_05680	9.388e-157	499.0	COG0340@1|root,arCOG01940@2157|Archaea,41SI3@651137|Thaumarchaeota	651137|Thaumarchaeota	H	biotin-(Acetyl-CoA-carboxylase) ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS3_k127_4222281_0	1229909.NSED_00745	1.017e-146	466.0	COG0107@1|root,arCOG00617@2157|Archaea,41S9A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_4222281_2	1229909.NSED_00750	1.354e-58	204.0	COG0139@1|root,arCOG02676@2157|Archaea,41SPE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
CMS3_k127_4222281_3	1229909.NSED_00755	8e-57	204.0	arCOG08828@1|root,arCOG08828@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4222281_1	1229909.NSED_00760	3.402e-73	247.0	COG0498@1|root,arCOG01434@2157|Archaea,41SEI@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS3_k127_424286_8	436308.Nmar_1306	1.501e-31	124.0	COG0640@1|root,arCOG03067@2157|Archaea,41TA3@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_424286_9	436308.Nmar_1271	3.436e-26	119.0	COG0517@1|root,arCOG00600@2157|Archaea,41TAT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS3_k127_424286_7	1229909.NSED_02900	3.278e-58	205.0	COG0432@1|root,arCOG04214@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_424286_3	1229909.NSED_09475	4.229e-214	670.0	COG0531@1|root,arCOG00009@2157|Archaea,41SXX@651137|Thaumarchaeota	651137|Thaumarchaeota	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS3_k127_424286_6	436308.Nmar_1770	6.624e-81	274.0	arCOG08811@1|root,arCOG08811@2157|Archaea,41T85@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_424286_0	1229909.NSED_09490	3.15e-286	882.0	COG0174@1|root,arCOG01909@2157|Archaea,41SD6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM glutamine synthetase, type I	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS3_k127_424286_2	1229909.NSED_09495	1.647e-263	816.0	COG1509@1|root,arCOG03246@2157|Archaea,41SY6@651137|Thaumarchaeota	651137|Thaumarchaeota	E	TIGRFAM lysine 2,3-aminomutase YodO family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_424286_1	436308.Nmar_1773	2.468e-281	873.0	COG0668@1|root,arCOG01568@2157|Archaea,41SYX@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
CMS3_k127_424286_4	1229909.NSED_09505	9.457e-132	426.0	COG0462@1|root,arCOG00067@2157|Archaea,41SH1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
CMS3_k127_424286_5	1229909.NSED_09510	3.494e-124	402.0	COG1041@1|root,arCOG00047@2157|Archaea	2157|Archaea	L	RNA methylase	trmG10	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
CMS3_k127_4405832_0	1229909.NSED_03260	6.044e-90	297.0	COG1028@1|root,arCOG01259@2157|Archaea,41SXY@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS3_k127_4405832_1	1131266.ARWQ01000006_gene258	1.797e-68	238.0	COG1628@1|root,arCOG00928@2157|Archaea,41SMQ@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Protein of unknown function DUF99	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
CMS3_k127_4405832_3	1229909.NSED_03250	6.252e-28	113.0	arCOG08753@1|root,arCOG08753@2157|Archaea,41T9W@651137|Thaumarchaeota	651137|Thaumarchaeota	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4405832_2	1229909.NSED_03245	1.326e-33	131.0	COG0644@1|root,arCOG00570@2157|Archaea,41S82@651137|Thaumarchaeota	651137|Thaumarchaeota	C	geranylgeranyl reductase	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_oxidored,Trp_halogenase
CMS3_k127_4441168_0	436308.Nmar_0746	6.757e-105	342.0	COG2107@1|root,arCOG00654@2157|Archaea,41SB8@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CMS3_k127_4441168_1	436308.Nmar_0745	6.623e-48	172.0	arCOG10539@1|root,arCOG10539@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4441168_3	1131266.ARWQ01000002_gene611	1.267e-18	89.0	arCOG10538@1|root,arCOG10538@2157|Archaea,41T9G@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4441168_2	436308.Nmar_0968	1.247e-32	129.0	arCOG08680@1|root,arCOG08680@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4486782_2	436308.Nmar_1367	1.253e-70	246.0	arCOG08650@1|root,arCOG08650@2157|Archaea,41SZ5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4486782_1	436308.Nmar_1366	2.11e-104	346.0	COG0500@1|root,COG2835@1|root,arCOG01791@2157|Archaea,arCOG04124@2157|Archaea,41T4S@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4486782_3	1229909.NSED_02035	3.088e-08	57.0	arCOG11430@1|root,arCOG11430@2157|Archaea	1229909.NSED_02035|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4486782_0	436308.Nmar_0380	6.399e-109	357.0	arCOG10517@1|root,arCOG10517@2157|Archaea,41T0I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4520498_3	1229909.NSED_01620	6.015e-125	404.0	COG1691@1|root,arCOG02465@2157|Archaea,41SCY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS3_k127_4520498_0	1229909.NSED_01625	7.087e-175	550.0	COG0039@1|root,arCOG00246@2157|Archaea,41S7Z@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Belongs to the LDH MDH superfamily	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS3_k127_4520498_1	1229909.NSED_01630	3.252e-163	523.0	COG1641@1|root,arCOG02701@2157|Archaea,41SDC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS3_k127_4520498_4	1131266.ARWQ01000001_gene1169	2.315e-102	339.0	COG1606@1|root,arCOG00043@2157|Archaea,41SF3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	tRNA methyl transferase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	QueC
CMS3_k127_4520498_2	436308.Nmar_0341	3.472e-135	436.0	COG1104@1|root,arCOG00066@2157|Archaea,41SB1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_4524395_0	1229909.NSED_03230	2.437e-209	658.0	arCOG08742@1|root,arCOG08742@2157|Archaea,41SS8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4524395_2	436308.Nmar_0629	2.059e-95	317.0	arCOG01781@1|root,arCOG01781@2157|Archaea,41T0U@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS3_k127_4524395_4	1229909.NSED_02870	1.029e-06	52.0	arCOG12097@1|root,arCOG12097@2157|Archaea	1229909.NSED_02870|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4524395_1	1229909.NSED_03245	2.584e-138	443.0	COG0644@1|root,arCOG00570@2157|Archaea,41S82@651137|Thaumarchaeota	651137|Thaumarchaeota	C	geranylgeranyl reductase	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_oxidored,Trp_halogenase
CMS3_k127_4554988_2	436308.Nmar_0292	1.991e-73	248.0	COG0456@1|root,arCOG00833@2157|Archaea,41SIY@651137|Thaumarchaeota	651137|Thaumarchaeota	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS3_k127_4554988_3	1229909.NSED_01415	7.313e-31	123.0	COG5625@1|root,arCOG04189@2157|Archaea,41T7F@651137|Thaumarchaeota	651137|Thaumarchaeota	K	HTH DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4554988_1	436308.Nmar_0294	1.121e-146	468.0	COG2520@1|root,arCOG00033@2157|Archaea,41S7P@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Met-10+ like-protein	-	-	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
CMS3_k127_4554988_0	436308.Nmar_0295	0.0	1002.0	COG1245@1|root,arCOG00187@2157|Archaea,41S8K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
CMS3_k127_4559133_1	436308.Nmar_1367	3.201e-52	188.0	arCOG08650@1|root,arCOG08650@2157|Archaea,41SZ5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4559133_0	436308.Nmar_1368	1.679e-141	452.0	COG0457@1|root,arCOG03038@2157|Archaea,41SMV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
CMS3_k127_4559133_2	436308.Nmar_1369	3.167e-23	99.0	arCOG08651@1|root,arCOG08651@2157|Archaea,41TB6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4563070_5	1229909.NSED_02725	1.434e-83	280.0	COG1208@1|root,arCOG00663@2157|Archaea,41SGT@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS3_k127_4563070_3	436308.Nmar_0542	1.333e-152	493.0	COG0351@1|root,arCOG00020@2157|Archaea,41SA1@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Phosphomethylpyrimidine kinase	-	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K21219	ko00730,ko01100,map00730,map01100	-	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
CMS3_k127_4563070_7	1229909.NSED_02740	3.906e-16	80.0	COG1656@1|root,arCOG04290@2157|Archaea	2157|Archaea	L	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
CMS3_k127_4563070_0	436308.Nmar_0543	5.167e-268	827.0	COG0422@1|root,arCOG02741@2157|Archaea,41S5Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein ThiC	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
CMS3_k127_4563070_6	797304.Natgr_2288	9.918e-17	85.0	COG1184@1|root,arCOG01127@2157|Archaea,2XUMH@28890|Euryarchaeota,23SF4@183963|Halobacteria	183963|Halobacteria	J	Belongs to the eIF-2B alpha beta delta subunits family	tif2Ba	-	-	-	-	-	-	-	-	-	-	-	IF-2B,NUDIX
CMS3_k127_4563070_4	1229909.NSED_02760	7.002e-151	480.0	COG0722@1|root,arCOG00245@2157|Archaea,41SM0@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS3_k127_4563070_1	1229909.NSED_02765	2.561e-228	714.0	COG0436@1|root,COG1605@1|root,arCOG01130@2157|Archaea,arCOG02098@2157|Archaea,41SBV@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Chorismate mutase type II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,CM_2
CMS3_k127_4563070_2	436308.Nmar_0547	4.715e-203	635.0	COG0082@1|root,arCOG04133@2157|Archaea,41SC3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS3_k127_4807040_0	436308.Nmar_1490	5.208e-226	700.0	COG0180@1|root,arCOG01887@2157|Archaea,41SDK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS3_k127_4807040_1	1229909.NSED_08195	9.795e-199	623.0	COG0016@1|root,arCOG00410@2157|Archaea,41S9U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Phenylalanyl-tRNA synthetase alpha subunit	-	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
CMS3_k127_4812614_1	1229909.NSED_08335	1.541e-85	284.0	COG2304@1|root,arCOG02900@2157|Archaea,41SDY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4812614_4	1121346.KB899850_gene143	8.28e-66	243.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,26QN7@186822|Paenibacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS3_k127_4812614_3	1229909.NSED_08345	1.002e-68	235.0	arCOG04405@1|root,arCOG04405@2157|Archaea	2157|Archaea	S	ASCH domain	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
CMS3_k127_4812614_0	436308.Nmar_1519	6.606e-105	342.0	COG2101@1|root,arCOG01764@2157|Archaea,41SZD@651137|Thaumarchaeota	651137|Thaumarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	-	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
CMS3_k127_4812614_7	436308.Nmar_1520	5.395e-28	114.0	arCOG10588@1|root,arCOG10588@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4812614_2	436308.Nmar_1521	1.908e-84	283.0	arCOG10589@1|root,arCOG10589@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4812614_5	436308.Nmar_1522	3.835e-49	184.0	arCOG08643@1|root,arCOG08643@2157|Archaea,41T5M@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4812614_6	436308.Nmar_1523	6.419e-49	177.0	COG0347@1|root,arCOG02305@2157|Archaea,41TB5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_4838845_7	930945.SiRe_1056	1.503e-08	63.0	COG1746@1|root,arCOG04249@2157|Archaea,2XQ3X@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
CMS3_k127_4838845_3	436308.Nmar_1783	1.648e-114	373.0	COG2112@1|root,arCOG01182@2157|Archaea,41SJV@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Ser thr protein kinase	-	-	-	ko:K07176	-	-	-	-	ko00000	-	-	-	RIO1
CMS3_k127_4838845_1	1229909.NSED_05505	1.043e-165	524.0	COG1405@1|root,arCOG01981@2157|Archaea,41SXZ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_4838845_5	1229909.NSED_01175	1.194e-28	117.0	COG1581@1|root,arCOG01753@2157|Archaea,41SQ4@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	-	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
CMS3_k127_4838845_6	1229909.NSED_07345	2.332e-23	98.0	arCOG03272@1|root,arCOG03272@2157|Archaea	2157|Archaea	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS3_k127_4838845_2	436308.Nmar_1003	3.238e-120	390.0	COG3741@1|root,arCOG08266@2157|Archaea	2157|Archaea	E	N-formylglutamate amidohydrolase	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
CMS3_k127_4838845_0	436308.Nmar_1004	7.406e-287	887.0	COG0405@1|root,arCOG04053@2157|Archaea	2157|Archaea	E	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS3_k127_4838845_4	436308.Nmar_1008	1.228e-111	376.0	COG0458@1|root,COG0624@1|root,arCOG01107@2157|Archaea,arCOG01596@2157|Archaea	2157|Archaea	EF	ATP-grasp domain	cxp2	-	3.4.17.11,3.5.1.18,6.3.2.4	ko:K01295,ko:K01439,ko:K01921,ko:K16181	ko00300,ko00473,ko00550,ko01100,ko01120,ko01230,ko01502,map00300,map00473,map00550,map01100,map01120,map01230,map01502	M00016	R01150,R02734,R10011	RC00064,RC00090,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011	-	-	-	ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C,M20_dimer,Peptidase_M20
CMS3_k127_4846749_11	1229909.NSED_04805	1.232e-31	128.0	arCOG03871@1|root,arCOG03871@2157|Archaea	2157|Archaea	S	TIGRFAM archaeal flagellin N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4846749_4	1229909.NSED_04800	1.033e-80	288.0	COG2304@1|root,arCOG02900@2157|Archaea	2157|Archaea	O	von Willebrand factor, type A	-	-	-	ko:K04043,ko:K07114	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko02000,ko03019,ko03029,ko03110,ko04147	1.A.13.2.2,1.A.13.2.3,1.A.33.1	-	-	HSP70,VWA,VWA_2
CMS3_k127_4846749_18	1229909.NSED_04790	2.048e-12	74.0	arCOG05517@1|root,arCOG05517@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4846749_2	1229909.NSED_04795	3.16e-142	463.0	COG0714@1|root,arCOG00441@2157|Archaea	2157|Archaea	V	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924,ko:K04748	-	-	R00294	RC02794	ko00000,ko01000	3.D.4.10	-	-	AAA_5,CbbQ_C,HHH_5
CMS3_k127_4846749_16	1229909.NSED_00425	2.824e-21	104.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS3_k127_4846749_13	1229909.NSED_04775	5.336e-25	109.0	COG3353@1|root,arCOG01824@2157|Archaea	2157|Archaea	N	Archaeal flagellar protein F	flaF	-	-	ko:K07329	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Arch_flagellin
CMS3_k127_4846749_12	1229909.NSED_04780	2.391e-28	133.0	arCOG03871@1|root,arCOG03871@2157|Archaea	2157|Archaea	S	TIGRFAM archaeal flagellin N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4846749_3	1229909.NSED_04760	1.666e-97	327.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
CMS3_k127_4846749_6	1229909.NSED_04755	3.086e-74	259.0	COG0467@1|root,arCOG01171@2157|Archaea,41TA0@651137|Thaumarchaeota	651137|Thaumarchaeota	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
CMS3_k127_4846749_0	436308.Nmar_0863	6.156e-201	631.0	COG1915@1|root,arCOG04422@2157|Archaea,41SBQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
CMS3_k127_4846749_9	436308.Nmar_0862	2.803e-51	183.0	arCOG08655@1|root,arCOG08655@2157|Archaea,41SR9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4846749_10	1229909.NSED_04740	3.789e-39	147.0	arCOG10555@1|root,arCOG10555@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4846749_14	436308.Nmar_0860	3.846e-24	103.0	arCOG10554@1|root,arCOG10554@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4846749_8	1229909.NSED_04730	4.447e-57	205.0	COG1896@1|root,arCOG04311@2157|Archaea,41SQE@651137|Thaumarchaeota	651137|Thaumarchaeota	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
CMS3_k127_4846749_5	1229909.NSED_04725	1.902e-75	258.0	COG2096@1|root,arCOG00489@2157|Archaea,41T2I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS3_k127_4846749_1	1229909.NSED_00895	6.091e-180	568.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
CMS3_k127_4866898_0	436308.Nmar_0088	0.0	998.0	COG1201@1|root,arCOG00557@2157|Archaea,41S8P@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DEAD/H associated	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS3_k127_4866898_1	436308.Nmar_0089	4.328e-152	484.0	COG1599@1|root,arCOG01510@2157|Archaea,41S9M@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
CMS3_k127_4961662_0	1229909.NSED_00535	0.0004386	52.0	arCOG08777@1|root,arCOG08777@2157|Archaea	1229909.NSED_00535|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4977749_14	1459636.NTE_00775	1.646e-14	75.0	COG2102@1|root,arCOG00035@2157|Archaea,41SHD@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Diphthamide synthase	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
CMS3_k127_4977749_0	1229909.NSED_02675	7.596e-255	789.0	COG0541@1|root,arCOG01228@2157|Archaea,41SDP@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	srp54	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS3_k127_4977749_3	1229909.NSED_02680	3.828e-146	472.0	COG1258@1|root,arCOG01015@2157|Archaea,41SHC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	-	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	-
CMS3_k127_4977749_4	436308.Nmar_0533	5.348e-123	397.0	arCOG08681@1|root,arCOG08681@2157|Archaea,41SH9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4977749_5	1229909.NSED_05045	2.547e-75	255.0	arCOG08730@1|root,arCOG08730@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4977749_12	436308.Nmar_1018	1.361e-27	115.0	arCOG10569@1|root,arCOG10569@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4977749_10	1229909.NSED_06625	1.348e-35	139.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_4977749_11	1229909.NSED_06630	3.399e-31	127.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8M@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_4977749_13	1131266.ARWQ01000005_gene843	9.683e-23	98.0	COG1998@1|root,arCOG04183@2157|Archaea,41SWB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
CMS3_k127_4977749_7	436308.Nmar_0535	1.17e-46	171.0	COG2004@1|root,arCOG04182@2157|Archaea,41SWI@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS24 family	-	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	-
CMS3_k127_4977749_15	985053.VMUT_1261	2.724e-12	74.0	COG1547@1|root,arCOG03705@2157|Archaea,2XSJA@28889|Crenarchaeota	28889|Crenarchaeota	S	Domain of unknown function (DUF309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF309
CMS3_k127_4977749_1	436308.Nmar_0537	1.682e-231	722.0	COG3635@1|root,arCOG01696@2157|Archaea,41S6M@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
CMS3_k127_4977749_2	1229909.NSED_02710	1.751e-203	636.0	COG1085@1|root,arCOG00422@2157|Archaea,41S6T@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
CMS3_k127_4977749_9	1229909.NSED_02715	3.525e-40	153.0	arCOG08683@1|root,arCOG08683@2157|Archaea,41SUM@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4977749_6	436308.Nmar_0540	8.797e-58	203.0	COG0454@1|root,arCOG00826@2157|Archaea,41T2E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
CMS3_k127_4977749_8	436308.Nmar_0541	2.997e-41	153.0	COG1208@1|root,arCOG00666@2157|Archaea	2157|Archaea	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS3_k127_4982647_4	1229909.NSED_09155	1.687e-111	364.0	COG1701@1|root,arCOG04262@2157|Archaea,41SXP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pfam:DUF137	-	-	6.3.2.36	ko:K09722	ko00410,ko00770,ko01100,map00410,map00770,map01100	-	R09379	RC00096,RC00141	ko00000,ko00001,ko01000	-	-	-	PPS_PS
CMS3_k127_4982647_5	1459636.NTE_02601	7.826e-95	318.0	COG0413@1|root,arCOG00584@2157|Archaea,41SZX@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS3_k127_4982647_0	1229909.NSED_09165	1.323e-205	646.0	COG0452@1|root,arCOG01704@2157|Archaea,41SYG@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS3_k127_4982647_3	436308.Nmar_1722	2.014e-123	401.0	COG0500@1|root,arCOG04347@2157|Archaea,41T35@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4982647_7	1229909.NSED_09175	2.609e-47	174.0	arCOG10600@1|root,arCOG10600@2157|Archaea,41T8K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_4982647_1	436308.Nmar_1724	1.036e-195	613.0	COG0006@1|root,arCOG01000@2157|Archaea,41T14@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS3_k127_4982647_2	436308.Nmar_1725	4.299e-183	576.0	COG0301@1|root,arCOG00038@2157|Archaea,41T1A@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
CMS3_k127_4982647_6	1229909.NSED_09195	6.075e-59	204.0	COG1782@1|root,arCOG00543@2157|Archaea,41T05@651137|Thaumarchaeota	651137|Thaumarchaeota	S	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_7,Lactamase_B_6,RMMBL
CMS3_k127_5001003_23	1229909.NSED_02325	1.042e-31	125.0	COG0197@1|root,arCOG04113@2157|Archaea,41SKN@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS3_k127_5001003_20	436308.Nmar_0213	1.757e-44	162.0	arCOG10521@1|root,arCOG10521@2157|Archaea,41T8A@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_10	436308.Nmar_0450	2.578e-96	318.0	COG1676@1|root,arCOG01701@2157|Archaea,41SJY@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
CMS3_k127_5001003_8	1229909.NSED_02335	1.818e-110	360.0	arCOG07871@1|root,arCOG07871@2157|Archaea,41T28@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1061 DNA or RNA helicases of superfamily II	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_17	1229909.NSED_08100	2.884e-61	214.0	COG1522@1|root,arCOG01580@2157|Archaea,41T4E@651137|Thaumarchaeota	651137|Thaumarchaeota	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
CMS3_k127_5001003_5	1229909.NSED_05525	1.66e-138	445.0	COG1708@1|root,arCOG01201@2157|Archaea	2157|Archaea	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS3_k127_5001003_12	1229909.NSED_06620	1.412e-78	271.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_5001003_29	1229909.NSED_01035	2.114e-15	77.0	COG5466@1|root,arCOG05278@2157|Archaea	2157|Archaea	S	small metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
CMS3_k127_5001003_15	1459636.NTE_02269	8.005e-74	252.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS3_k127_5001003_32	1229909.NSED_02950	2.799e-10	64.0	COG1938@1|root,arCOG00347@2157|Archaea	2157|Archaea	S	COG1938 Archaeal enzymes of ATP-grasp superfamily	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
CMS3_k127_5001003_31	930945.SiRe_2402	1.13e-14	79.0	COG0589@1|root,arCOG02053@2157|Archaea,2XQTK@28889|Crenarchaeota	28889|Crenarchaeota	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5001003_28	1229909.NSED_05735	1.385e-21	100.0	COG0589@1|root,arCOG02053@2157|Archaea,41TB2@651137|Thaumarchaeota	651137|Thaumarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_5001003_14	1229909.NSED_08835	2.011e-77	262.0	COG1522@1|root,arCOG01117@2157|Archaea	1229909.NSED_08835|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_4	1229909.NSED_02040	5.078e-139	445.0	COG4742@1|root,arCOG04362@2157|Archaea,41SGE@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS3_k127_5001003_30	1229909.NSED_06645	3.281e-15	76.0	arCOG11430@1|root,arCOG11430@2157|Archaea	1229909.NSED_06645|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_11	436308.Nmar_1015	3.236e-83	288.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_33	436308.Nmar_1282	8.636e-07	54.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_24	386456.JQKN01000018_gene600	5.33e-29	119.0	COG3189@1|root,arCOG06027@2157|Archaea,2XZN7@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
CMS3_k127_5001003_3	1131266.ARWQ01000009_gene951	7.778e-162	513.0	COG0535@1|root,arCOG00938@2157|Archaea,41SXS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS3_k127_5001003_19	523841.HFX_2740	1.439e-56	208.0	COG2086@1|root,arCOG00446@2157|Archaea,2XTB8@28890|Euryarchaeota,23TTZ@183963|Halobacteria	183963|Halobacteria	C	Electron transfer flavoprotein, beta subunit	etfB2	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS3_k127_5001003_2	1131266.ARWQ01000002_gene513	4.12e-165	527.0	COG2025@1|root,arCOG00448@2157|Archaea,41SZJ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS3_k127_5001003_0	1131266.ARWQ01000002_gene512	1.244e-291	905.0	COG0644@1|root,COG2440@1|root,arCOG00570@2157|Archaea,arCOG01984@2157|Archaea,41SXJ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS3_k127_5001003_16	1459636.NTE_02477	1.371e-68	240.0	COG0317@1|root,arCOG06870@2157|Archaea	2157|Archaea	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
CMS3_k127_5001003_18	436308.Nmar_1348	1.015e-56	199.0	COG0361@1|root,arCOG01179@2157|Archaea	2157|Archaea	J	Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits	eif1a	-	-	ko:K03236	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	eIF-1a
CMS3_k127_5001003_21	1229909.NSED_04275	3.607e-40	149.0	arCOG10548@1|root,arCOG10548@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_6	1459636.NTE_03244	1.698e-131	426.0	COG1237@1|root,arCOG00503@2157|Archaea	2157|Archaea	S	PFAM beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Lactamase_B_2
CMS3_k127_5001003_7	436308.Nmar_0466	4.043e-117	383.0	arCOG08732@1|root,arCOG08732@2157|Archaea,41SR6@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_27	1229909.NSED_02350	1.225e-21	94.0	arCOG08742@1|root,arCOG08742@2157|Archaea,41TAD@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_26	1131266.ARWQ01000010_gene36	4.504e-22	96.0	arCOG11928@1|root,arCOG11928@2157|Archaea,41T8Q@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_1	1229909.NSED_02355	6.085e-197	622.0	arCOG08733@1|root,arCOG08733@2157|Archaea,41SRN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_22	1229909.NSED_02360	8.374e-38	145.0	COG0457@1|root,arCOG03032@2157|Archaea,41T5X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS3_k127_5001003_13	436308.Nmar_0469	1.747e-78	265.0	arCOG10527@1|root,arCOG10527@2157|Archaea,41SPB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5001003_9	1229909.NSED_02370	1.738e-109	358.0	arCOG08734@1|root,arCOG08734@2157|Archaea,41SP9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5004802_3	436308.Nmar_1656	6.536e-39	146.0	COG0864@1|root,arCOG01008@2157|Archaea,41SQM@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
CMS3_k127_5004802_2	1459636.NTE_00032	5.096e-63	228.0	COG0803@1|root,arCOG01005@2157|Archaea,41T29@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS3_k127_5004802_1	1229909.NSED_08955	3.872e-133	427.0	COG1121@1|root,arCOG00201@2157|Archaea,41S7E@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
CMS3_k127_5004802_0	436308.Nmar_1653	1.735e-133	429.0	COG1108@1|root,arCOG01006@2157|Archaea,41SG2@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS3_k127_5024248_4	1229909.NSED_08555	1.332e-25	116.0	arCOG08793@1|root,arCOG08793@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5024248_1	1229909.NSED_05300	8.866e-111	366.0	COG1378@1|root,arCOG02038@2157|Archaea	2157|Archaea	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
CMS3_k127_5024248_0	1229909.NSED_02835	3.37e-127	409.0	COG0580@1|root,arCOG04431@2157|Archaea,41S5R@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188,ko:K09866	ko04962,ko04976,map04962,map04976	-	-	-	ko00000,ko00001,ko02000	1.A.8	-	-	MIP
CMS3_k127_5024248_2	1229909.NSED_02830	1.021e-86	287.0	COG1225@1|root,arCOG00310@2157|Archaea,41SN5@651137|Thaumarchaeota	651137|Thaumarchaeota	O	AhpC/TSA antioxidant enzyme	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS3_k127_5024248_3	436308.Nmar_0559	1.046e-39	153.0	arCOG08027@1|root,arCOG08027@2157|Archaea,41T8U@651137|Thaumarchaeota	651137|Thaumarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5047563_2	436308.Nmar_1559	3.009e-29	117.0	COG0040@1|root,arCOG02208@2157|Archaea,41SCJ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ATP phosphoribosyltransferase	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS3_k127_5047563_0	1229909.NSED_00705	1.232e-212	666.0	COG1257@1|root,arCOG04260@2157|Archaea,41SAU@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
CMS3_k127_5047563_1	1229909.NSED_00700	7.169e-183	577.0	COG2133@1|root,arCOG02796@2157|Archaea,41S7F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_5102530_13	436308.Nmar_0525	3.947e-36	138.0	COG0727@1|root,arCOG02579@2157|Archaea,41T3E@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS3_k127_5102530_0	1229909.NSED_02630	5.147e-197	618.0	COG1064@1|root,arCOG01455@2157|Archaea,41SA9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5102530_6	1229909.NSED_02625	2.171e-110	360.0	COG1354@1|root,arCOG02610@2157|Archaea,41SMU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	-
CMS3_k127_5102530_8	1229909.NSED_02620	1.924e-93	309.0	COG1386@1|root,arCOG02613@2157|Archaea,41SIC@651137|Thaumarchaeota	651137|Thaumarchaeota	K	segregation and condensation protein	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS3_k127_5102530_10	1229909.NSED_02615	7.273e-62	214.0	COG2007@1|root,arCOG04154@2157|Archaea,41SP2@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein S8e	rps8e	-	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
CMS3_k127_5102530_11	436308.Nmar_0519	6.409e-46	167.0	COG1400@1|root,arCOG01217@2157|Archaea,41SR5@651137|Thaumarchaeota	651137|Thaumarchaeota	U	SRP19 protein	-	-	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
CMS3_k127_5102530_14	436308.Nmar_0518	1.871e-33	130.0	COG3277@1|root,arCOG02466@2157|Archaea,41SVG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	RNA-binding protein involved in rRNA processing	-	-	-	ko:K07569	-	-	-	-	ko00000,ko03009	-	-	-	Gar1
CMS3_k127_5102530_1	436308.Nmar_0517	1.775e-181	570.0	COG1405@1|root,arCOG01981@2157|Archaea,41S8Y@651137|Thaumarchaeota	651137|Thaumarchaeota	K	factor TFIIB	-	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
CMS3_k127_5102530_4	1229909.NSED_02595	4.566e-150	477.0	COG0396@1|root,arCOG04236@2157|Archaea,41SE1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS3_k127_5102530_15	1229909.NSED_02590	2.57e-19	89.0	COG1872@1|root,arCOG04058@2157|Archaea,41TAX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS3_k127_5102530_5	1131266.ARWQ01000005_gene828	1.013e-110	361.0	COG3253@1|root,arCOG03031@2157|Archaea,41SGX@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
CMS3_k127_5102530_2	436308.Nmar_0514	1.679e-178	562.0	COG0667@1|root,arCOG01617@2157|Archaea,41S90@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS3_k127_5102530_12	1229909.NSED_02575	3.344e-44	162.0	arCOG10528@1|root,arCOG10528@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5102530_3	1131266.ARWQ01000005_gene824	8.18e-162	515.0	COG1522@1|root,arCOG01628@2157|Archaea,41SA2@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5102530_9	1229909.NSED_02565	2.086e-66	232.0	COG1648@1|root,arCOG01044@2157|Archaea,41SN9@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Siroheme synthase	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
CMS3_k127_5102530_7	436308.Nmar_0510	9.682e-106	346.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_5106159_0	1229909.NSED_03095	2.251e-201	630.0	COG1060@1|root,arCOG00656@2157|Archaea,41SDT@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.77	ko:K11781	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_5106159_1	436308.Nmar_0591	1.106e-178	569.0	COG0312@1|root,arCOG00322@2157|Archaea,41T72@651137|Thaumarchaeota	651137|Thaumarchaeota	S	modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_5106159_2	436308.Nmar_0590	5.658e-79	269.0	COG0530@1|root,arCOG02881@2157|Archaea,41T1S@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS3_k127_51181_0	436308.Nmar_1794	0.0	1322.0	COG1933@1|root,arCOG04447@2157|Archaea,41SYW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	-	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	PolC_DP2
CMS3_k127_51181_1	1229909.NSED_09600	1.147e-32	126.0	COG0112@1|root,arCOG00070@2157|Archaea,41S7U@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS3_k127_5121884_4	1229909.NSED_07875	8.099e-34	130.0	COG3432@1|root,arCOG01055@2157|Archaea,41SST@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
CMS3_k127_5121884_10	1229909.NSED_07880	3.114e-09	61.0	arCOG11531@1|root,arCOG11531@2157|Archaea,41TAQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5121884_8	1131266.ARWQ01000001_gene1078	2.711e-16	79.0	arCOG10410@1|root,arCOG10410@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5121884_0	1229909.NSED_07955	1.75e-209	660.0	COG1109@1|root,arCOG00767@2157|Archaea,41SC1@651137|Thaumarchaeota	651137|Thaumarchaeota	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS3_k127_5121884_3	374847.Kcr_0043	2.009e-45	176.0	COG0611@1|root,arCOG00638@2157|Archaea	2157|Archaea	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_5121884_2	1229909.NSED_06890	9.006e-50	181.0	COG4088@1|root,arCOG01041@2157|Archaea	2157|Archaea	F	PFAM Chromatin associated protein KTI12	pstK	-	2.7.1.164,2.7.1.25	ko:K00860,ko:K10837	ko00230,ko00450,ko00920,ko00970,ko01100,ko01120,map00230,map00450,map00920,map00970,map01100,map01120	M00176	R00509,R04928,R08223	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_33,KTI12
CMS3_k127_5121884_9	1229909.NSED_06250	1.132e-09	60.0	arCOG10955@1|root,arCOG10955@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5121884_5	436308.Nmar_0429	6.071e-25	108.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5121884_6	1229909.NSED_03275	1.182e-19	93.0	arCOG10531@1|root,arCOG10531@2157|Archaea,41T4F@651137|Thaumarchaeota	651137|Thaumarchaeota	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5121884_7	1229909.NSED_07965	1.209e-16	84.0	arCOG11453@1|root,arCOG11453@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5121884_1	1229909.NSED_07970	3.613e-80	269.0	COG0100@1|root,arCOG04240@2157|Archaea,41SII@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Located on the platform of the 30S subunit	rps11	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS3_k127_5142187_5	1229909.NSED_07430	2.026e-15	87.0	arCOG08764@1|root,arCOG08764@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5142187_4	1229909.NSED_07010	2.803e-85	292.0	COG3794@1|root,arCOG10350@1|root,arCOG02926@2157|Archaea,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Kazal_1
CMS3_k127_5142187_0	436308.Nmar_1245	8.328e-303	942.0	COG0419@1|root,COG1122@1|root,arCOG00202@2157|Archaea,arCOG00368@2157|Archaea,41S9P@651137|Thaumarchaeota	651137|Thaumarchaeota	LP	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15
CMS3_k127_5142187_2	1229909.NSED_06980	3.096e-195	613.0	COG0420@1|root,arCOG00397@2157|Archaea,41S68@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos_2
CMS3_k127_5142187_1	436308.Nmar_1243	2.447e-295	910.0	COG0433@1|root,arCOG00280@2157|Archaea,41SE3@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
CMS3_k127_5142187_3	436308.Nmar_1242	2.546e-155	492.0	COG1630@1|root,arCOG00367@2157|Archaea,41SJX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
CMS3_k127_5142187_6	1229909.NSED_02965	2.194e-09	59.0	arCOG07473@1|root,arCOG07473@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5184224_6	1131266.ARWQ01000015_gene746	1.086e-43	159.0	COG1245@1|root,arCOG00187@2157|Archaea,41S8K@651137|Thaumarchaeota	651137|Thaumarchaeota	E	RNase L inhibitor, RLI	-	-	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
CMS3_k127_5184224_1	1229909.NSED_01430	3.373e-243	758.0	COG0260@1|root,arCOG04322@2157|Archaea,41SYD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS3_k127_5184224_7	1229909.NSED_01435	1.202e-37	145.0	arCOG08747@1|root,arCOG08747@2157|Archaea,41T48@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5184224_4	1131266.ARWQ01000014_gene88	2.944e-76	261.0	COG0500@1|root,arCOG04347@2157|Archaea,41SQN@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	Nodulation protein S (NodS)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS3_k127_5184224_3	1131266.ARWQ01000014_gene90	6.789e-98	324.0	COG1575@1|root,arCOG00480@2157|Archaea,41SNA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the MenA family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5184224_5	1131266.ARWQ01000014_gene92	3.827e-51	184.0	COG0662@1|root,arCOG03003@2157|Archaea,41TAC@651137|Thaumarchaeota	651137|Thaumarchaeota	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5184224_0	436308.Nmar_0299	0.0	1000.0	COG0036@1|root,COG3959@1|root,arCOG01053@2157|Archaea,arCOG05046@2157|Archaea,41SBE@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim,Transketolase_N
CMS3_k127_5184224_2	436308.Nmar_0300	5.492e-164	519.0	COG3958@1|root,arCOG01051@2157|Archaea,41SEP@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS3_k127_5213074_1	1229909.NSED_00645	5.794e-66	230.0	arCOG05463@1|root,arCOG05463@2157|Archaea,41SR3@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5213074_0	436308.Nmar_1573	1.693e-198	620.0	COG0519@1|root,arCOG00085@2157|Archaea,41SDI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS3_k127_5222755_5	1229909.NSED_07415	1.111e-17	82.0	COG2159@1|root,arCOG01931@2157|Archaea	2157|Archaea	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS3_k127_5222755_1	1229909.NSED_06135	5.006e-79	265.0	arCOG10570@1|root,arCOG10570@2157|Archaea,41T75@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5222755_0	1229909.NSED_06130	0.0	1026.0	COG1028@1|root,arCOG01259@2157|Archaea,41S7V@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS3_k127_5222755_4	1229909.NSED_06125	1.841e-41	153.0	arCOG08727@1|root,arCOG08727@2157|Archaea,41T57@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5222755_3	1229909.NSED_06120	1.174e-64	222.0	arCOG08726@1|root,arCOG08726@2157|Archaea,41STN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5222755_2	1229909.NSED_06115	1.418e-77	260.0	COG1676@1|root,arCOG01701@2157|Archaea,41SHW@651137|Thaumarchaeota	651137|Thaumarchaeota	L	tRNA intron endonuclease, N-terminal domain	-	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
CMS3_k127_5233125_17	436308.Nmar_1060	0.0004981	44.0	arCOG10572@1|root,arCOG10572@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5233125_8	436308.Nmar_1059	1.193e-59	208.0	arCOG08684@1|root,arCOG08684@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5233125_4	436308.Nmar_1058	7.505e-101	331.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41SMJ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS3_k127_5233125_11	1229909.NSED_08840	8.671e-43	158.0	arCOG08729@1|root,arCOG08729@2157|Archaea,41T79@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5233125_12	517418.Ctha_2648	2.669e-37	147.0	COG2094@1|root,COG2094@2|Bacteria,1FDYR@1090|Chlorobi	1090|Chlorobi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
CMS3_k127_5233125_5	436308.Nmar_1056	3.568e-91	302.0	COG1573@1|root,arCOG00905@2157|Archaea,41SJ1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS3_k127_5233125_1	1229909.NSED_06185	2.585e-216	679.0	COG1530@1|root,arCOG00321@2157|Archaea,41T2C@651137|Thaumarchaeota	651137|Thaumarchaeota	L	modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS3_k127_5233125_3	1229909.NSED_06180	2.334e-111	371.0	COG0642@1|root,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,sCache_3_3
CMS3_k127_5233125_10	1229909.NSED_06170	9.531e-46	167.0	COG0784@1|root,arCOG02391@2157|Archaea,41TB0@651137|Thaumarchaeota	651137|Thaumarchaeota	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_5233125_0	1229909.NSED_06165	2.66e-290	901.0	COG1855@1|root,arCOG04116@2157|Archaea,41SX0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Large family of predicted nucleotide-binding domains	-	-	-	ko:K06865	-	-	-	-	ko00000	-	-	-	KH_1,T2SSE
CMS3_k127_5233125_7	1131266.ARWQ01000002_gene663	7.031e-68	233.0	COG1321@1|root,arCOG02100@2157|Archaea,41SQ9@651137|Thaumarchaeota	651137|Thaumarchaeota	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
CMS3_k127_5233125_9	436308.Nmar_1052	1.327e-52	187.0	arCOG08740@1|root,arCOG08740@2157|Archaea,41T52@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5233125_13	1131266.ARWQ01000029_gene981	3.818e-31	135.0	arCOG08793@1|root,arCOG08793@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5233125_6	436308.Nmar_1050	1.308e-76	259.0	COG1430@1|root,arCOG03116@2157|Archaea,41SP3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS3_k127_5233125_14	1229909.NSED_06145	1.557e-27	119.0	arCOG10571@1|root,arCOG10571@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5233125_2	1229909.NSED_06140	1.873e-113	370.0	COG0730@1|root,arCOG02050@2157|Archaea,41SKY@651137|Thaumarchaeota	651137|Thaumarchaeota	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS3_k127_5233125_16	1229909.NSED_06135	1.036e-07	53.0	arCOG10570@1|root,arCOG10570@2157|Archaea,41T75@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5276467_1	1229909.NSED_02185	7.607e-251	777.0	COG0065@1|root,arCOG01698@2157|Archaea,41S7A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS3_k127_5276467_5	436308.Nmar_0421	2.165e-91	301.0	COG0066@1|root,arCOG02230@2157|Archaea,41SIA@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS3_k127_5276467_0	1229909.NSED_02195	2.541e-277	856.0	COG0065@1|root,arCOG01698@2157|Archaea,41SYT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	3-isopropylmalate dehydratase, large subunit	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS3_k127_5276467_7	345219.Bcoa_2061	2.508e-69	240.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli,1ZAVC@1386|Bacillus	91061|Bacilli	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS3_k127_5276467_3	1229909.NSED_02205	1.284e-111	364.0	COG1208@1|root,arCOG00663@2157|Archaea	2157|Archaea	M	PFAM Nucleotidyl transferase	-	-	2.6.1.37,2.7.7.13	ko:K00966,ko:K03430	ko00051,ko00440,ko00520,ko01100,ko01110,ko01120,map00051,map00440,map00520,map01100,map01110,map01120	M00114,M00361,M00362	R00885,R04152	RC00002,RC00008,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	NTP_transferase
CMS3_k127_5276467_6	1229909.NSED_02210	4.176e-83	276.0	COG0088@1|root,arCOG04243@2157|Archaea,41SKT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the universal ribosomal protein uS9 family	-	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS3_k127_5276467_8	1229909.NSED_02215	5.292e-64	222.0	COG0102@1|root,arCOG04242@2157|Archaea,41SP4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS3_k127_5276467_9	399549.Msed_2144	3.227e-18	89.0	COG1727@1|root,arCOG00780@2157|Archaea,2XQV1@28889|Crenarchaeota	28889|Crenarchaeota	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18,Ribosomal_L27A
CMS3_k127_5276467_4	436308.Nmar_0428	7.93e-111	360.0	COG0202@1|root,arCOG04241@2157|Archaea,41SK0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	DNA-directed RNA polymerase, alpha subunit 40 kD subunit	-	-	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_A_bac,RNA_pol_L
CMS3_k127_5276467_2	436308.Nmar_0430	1.909e-119	386.0	COG1500@1|root,arCOG04187@2157|Archaea,41SC7@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	-	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
CMS3_k127_5420398_2	436308.Nmar_1394	5.155e-68	234.0	COG1867@1|root,arCOG01219@2157|Archaea,41SAG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family	-	-	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
CMS3_k127_5420398_0	436308.Nmar_1395	6.525e-114	368.0	COG0293@1|root,arCOG00079@2157|Archaea,41SIK@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS3_k127_5420398_1	436308.Nmar_1396	1.041e-80	273.0	COG1522@1|root,arCOG04153@2157|Archaea,41SP6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5420398_3	436308.Nmar_1397	4.427e-20	91.0	arCOG10583@1|root,arCOG10583@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5450607_2	436308.Nmar_1644	1.035e-82	277.0	arCOG08728@1|root,arCOG08728@2157|Archaea,41SW1@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5450607_1	436308.Nmar_1635	8.677e-126	406.0	COG0705@1|root,arCOG01768@2157|Archaea,41SKD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS3_k127_5450607_4	1229909.NSED_08905	6.378e-30	119.0	arCOG02240@1|root,arCOG02240@2157|Archaea,41SSM@651137|Thaumarchaeota	651137|Thaumarchaeota	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
CMS3_k127_5450607_0	436308.Nmar_1633	9.822e-147	468.0	COG0388@1|root,arCOG00062@2157|Archaea,41SF8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS3_k127_5450607_3	1131266.ARWQ01000009_gene926	1.112e-36	139.0	arCOG10412@1|root,arCOG10412@2157|Archaea,41SS9@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5457321_4	1229909.NSED_04220	1.087e-32	130.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T81@651137|Thaumarchaeota	651137|Thaumarchaeota	S	COG4618 ABC-type protease lipase transport system, ATPase and permease components	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5457321_3	436308.Nmar_1524	6.688e-39	145.0	COG1522@1|root,arCOG01117@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
CMS3_k127_5457321_0	436308.Nmar_1525	4.836e-177	557.0	COG0042@1|root,arCOG00604@2157|Archaea	2157|Archaea	J	Dihydrouridine synthase (Dus)	dusA1	-	-	-	-	-	-	-	-	-	-	-	Dus
CMS3_k127_5457321_1	1229909.NSED_08405	2.69e-126	412.0	arCOG07561@1|root,arCOG07561@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3,VWA
CMS3_k127_5457321_2	1229909.NSED_08395	2.898e-83	278.0	arCOG07561@1|root,arCOG07561@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3,VWA
CMS3_k127_5486652_0	436308.Nmar_0510	9.441e-179	564.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_5486652_1	1229909.NSED_02555	8.018e-177	557.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS3_k127_5486652_2	1229909.NSED_02550	2.028e-23	101.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_55883_7	1229909.NSED_08225	1.794e-11	66.0	arCOG08038@1|root,arCOG08733@1|root,arCOG08038@2157|Archaea,arCOG08733@2157|Archaea	2157|Archaea	S	protein secretion by the type IV secretion system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_55883_0	1131266.ARWQ01000001_gene1155	1.218e-177	560.0	COG0644@1|root,arCOG00570@2157|Archaea,41SCG@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CMS3_k127_55883_1	1229909.NSED_01720	5.636e-134	428.0	COG0727@1|root,arCOG02579@2157|Archaea,41SH8@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS3_k127_55883_4	1229909.NSED_01715	4.779e-55	194.0	arCOG10523@1|root,arCOG10523@2157|Archaea,41SSZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_55883_2	1229909.NSED_01710	1.727e-114	370.0	COG0049@1|root,arCOG04254@2157|Archaea,41S6U@651137|Thaumarchaeota	651137|Thaumarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS3_k127_55883_6	5297.GMQ_03568T0	1.477e-35	140.0	COG0048@1|root,KOG1749@2759|Eukaryota,39ZWD@33154|Opisthokonta,3P20Z@4751|Fungi,3V0CE@5204|Basidiomycota,2YDQB@29000|Pucciniomycotina	4751|Fungi	J	Ribosomal protein S12/S23	rps23	GO:0000462,GO:0001666,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006355,GO:0006357,GO:0006364,GO:0006396,GO:0006412,GO:0006450,GO:0006518,GO:0006606,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006950,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0015031,GO:0015833,GO:0015935,GO:0016070,GO:0016072,GO:0017038,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0023051,GO:0023056,GO:0030490,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034470,GO:0034504,GO:0034613,GO:0034641,GO:0034645,GO:0034660,GO:0036293,GO:0036294,GO:0042221,GO:0042254,GO:0042274,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045184,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0046907,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051169,GO:0051170,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051254,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070482,GO:0070727,GO:0070887,GO:0071453,GO:0071456,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990904,GO:2000112,GO:2000638,GO:2000640,GO:2001141	-	ko:K02973	ko03010,map03010	M00177	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS3_k127_55883_3	436308.Nmar_0353	6.174e-86	285.0	COG0195@1|root,arCOG01760@2157|Archaea,41SJQ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_2
CMS3_k127_55883_5	1229909.NSED_01695	2.397e-47	171.0	COG1911@1|root,arCOG01752@2157|Archaea,41SW9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PFAM ribosomal protein L7Ae L30e S12e Gadd45	-	-	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
CMS3_k127_5633981_1	1229909.NSED_08845	0.0004424	52.0	arCOG08733@1|root,arCOG08733@2157|Archaea,41SRN@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5633981_0	436308.Nmar_1199	3.163e-147	482.0	COG4257@1|root,arCOG03564@2157|Archaea,41SM7@651137|Thaumarchaeota	651137|Thaumarchaeota	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
CMS3_k127_5633981_2	1274374.CBLK010000077_gene4139	0.0004889	52.0	COG3507@1|root,COG4733@1|root,COG5184@1|root,COG5492@1|root,COG3507@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,1VA5K@1239|Firmicutes,4IUF6@91061|Bacilli,277KK@186822|Paenibacillaceae	91061|Bacilli	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,ChW,DUF5011,Laminin_G_3,SLH
CMS3_k127_56522_3	436308.Nmar_1583	6.849e-112	366.0	COG1270@1|root,arCOG04274@2157|Archaea,41S6I@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CMS3_k127_56522_2	1229909.NSED_00585	9.054e-125	404.0	COG1492@1|root,arCOG00105@2157|Archaea,41SG6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA
CMS3_k127_56522_1	1131266.ARWQ01000009_gene955	2.21e-136	442.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
CMS3_k127_56522_0	1229909.NSED_00570	5.32e-184	577.0	COG0136@1|root,arCOG00494@2157|Archaea,41SFD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	aspartate-semialdehyde dehydrogenase	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS3_k127_5734232_3	436308.Nmar_1068	4.719e-07	53.0	arCOG11451@1|root,arCOG11451@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5734232_2	1229909.NSED_06230	8.292e-37	141.0	arCOG08788@1|root,arCOG08788@2157|Archaea,41T6K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5734232_0	436308.Nmar_1066	1.59e-258	799.0	COG0017@1|root,arCOG00406@2157|Archaea,41S93@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS3_k127_5734232_1	436308.Nmar_1065	1.883e-87	290.0	COG0195@1|root,arCOG01761@2157|Archaea,41T4Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5734402_5	436308.Nmar_1224	2.266e-40	151.0	arCOG07192@1|root,arCOG07192@2157|Archaea,41SVA@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5734402_0	1229909.NSED_06870	1.094e-154	492.0	COG0109@1|root,arCOG00479@2157|Archaea,41SDQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS3_k127_5734402_1	1229909.NSED_06875	6.495e-148	475.0	COG3794@1|root,arCOG02926@2157|Archaea,arCOG02929@2157|Archaea,41SHN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_5734402_4	436308.Nmar_1227	2.736e-43	161.0	COG1310@1|root,arCOG01138@2157|Archaea,41SSV@651137|Thaumarchaeota	651137|Thaumarchaeota	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
CMS3_k127_5734402_3	436308.Nmar_1228	3.785e-47	173.0	COG2164@1|root,arCOG04488@2157|Archaea,41T6P@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
CMS3_k127_5734402_2	436308.Nmar_1357	4.014e-80	272.0	COG0778@1|root,arCOG00288@2157|Archaea,41T1J@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS3_k127_5743246_6	1229909.NSED_04715	2.41e-17	83.0	28HMW@1|root,2N5MZ@2157|Archaea,41T97@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5743246_5	1229909.NSED_04710	3.099e-38	143.0	arCOG08032@1|root,arCOG08032@2157|Archaea,41T69@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5743246_2	1229909.NSED_04700	2.635e-76	257.0	COG0346@1|root,arCOG02708@2157|Archaea,41SU3@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
CMS3_k127_5743246_3	436308.Nmar_0852	5.814e-63	218.0	arCOG08684@1|root,arCOG08684@2157|Archaea,41T7E@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5743246_4	1229909.NSED_04690	6.635e-61	212.0	arCOG10553@1|root,arCOG10553@2157|Archaea,41T8J@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5743246_0	1229909.NSED_04685	8.921e-136	435.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T26@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS3_k127_5743246_1	1229909.NSED_04680	2.546e-77	260.0	arCOG08708@1|root,arCOG08708@2157|Archaea,41SPK@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5756110_11	436308.Nmar_0944	9.331e-45	163.0	COG1111@1|root,arCOG00872@2157|Archaea	2157|Archaea	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K03703,ko:K10896	ko03420,ko03460,map03420,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C,ResIII
CMS3_k127_5756110_13	1229909.NSED_05385	4.511e-15	78.0	arCOG11285@1|root,arCOG11285@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5756110_12	436308.Nmar_0942	9.418e-44	160.0	COG0760@1|root,arCOG07441@2157|Archaea,41SSK@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
CMS3_k127_5756110_4	1459636.NTE_02862	7.831e-163	526.0	arCOG00144@1|root,arCOG00144@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS3_k127_5756110_7	1229909.NSED_00905	4.8e-82	281.0	arCOG07526@1|root,arCOG07526@2157|Archaea	2157|Archaea	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone,Mrr_cat
CMS3_k127_5756110_10	436308.Nmar_1273	1.46e-57	212.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_5756110_1	1229909.NSED_05460	7.418e-317	974.0	COG1884@1|root,arCOG04232@2157|Archaea,41SBW@651137|Thaumarchaeota	651137|Thaumarchaeota	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS3_k127_5756110_3	436308.Nmar_0955	2.908e-164	520.0	COG1703@1|root,arCOG01226@2157|Archaea,41SFN@651137|Thaumarchaeota	651137|Thaumarchaeota	E	LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
CMS3_k127_5756110_0	1229909.NSED_05490	0.0	1384.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
CMS3_k127_5756110_8	1229909.NSED_05515	1.014e-80	269.0	COG2185@1|root,arCOG01710@2157|Archaea,41SJN@651137|Thaumarchaeota	651137|Thaumarchaeota	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CMS3_k127_5756110_2	436308.Nmar_0959	3.27e-194	608.0	COG0059@1|root,arCOG04465@2157|Archaea,41S65@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS3_k127_5756110_6	436308.Nmar_0960	1.81e-84	282.0	COG1056@1|root,arCOG00972@2157|Archaea,41T2U@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Cytidylyltransferase-like	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
CMS3_k127_5756110_5	1229909.NSED_05535	1.037e-158	504.0	COG3276@1|root,arCOG01564@2157|Archaea,41SCR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	elongation factor Tu	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
CMS3_k127_5756110_9	760192.Halhy_5172	5.859e-64	244.0	COG3210@1|root,COG3210@2|Bacteria,4PMJA@976|Bacteroidetes	976|Bacteroidetes	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS3_k127_5756915_1	1459636.NTE_03327	1.553e-114	381.0	arCOG08764@1|root,arCOG08764@2157|Archaea,41TBI@651137|Thaumarchaeota	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5756915_6	1229909.NSED_02870	6.724e-08	56.0	arCOG12097@1|root,arCOG12097@2157|Archaea	1229909.NSED_02870|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5756915_7	1229909.NSED_02065	9.145e-05	53.0	arCOG08643@1|root,arCOG10350@1|root,arCOG08643@2157|Archaea,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5756915_0	436308.Nmar_1207	2.748e-133	447.0	COG0642@1|root,arCOG02363@1|root,arCOG02358@2157|Archaea,arCOG02363@2157|Archaea	2157|Archaea	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K03406,ko:K07709	ko02020,ko02030,map02020,map02030	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,MCPsignal,PAS_9,dCache_1
CMS3_k127_5756915_3	436308.Nmar_1206	1.087e-32	130.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K02485,ko:K02490,ko:K03413	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_5756915_2	436308.Nmar_1203	4.43e-101	336.0	arCOG10580@1|root,arCOG10580@2157|Archaea	436308.Nmar_1203|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5756915_4	436308.Nmar_1204	3.288e-30	130.0	arCOG10350@1|root,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5756915_5	1131266.ARWQ01000009_gene944	2.666e-08	55.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5761057_4	1229909.NSED_03605	1.784e-94	311.0	COG0460@1|root,arCOG01351@2157|Archaea,41SAC@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
CMS3_k127_5761057_6	1229909.NSED_03600	2.18e-75	257.0	COG2016@1|root,arCOG00985@2157|Archaea,41SSC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	PUA domain	-	-	-	ko:K07575	-	-	-	-	ko00000	-	-	-	PUA
CMS3_k127_5761057_8	1459636.NTE_00004	7.698e-45	173.0	COG0468@1|root,arCOG00415@2157|Archaea	2157|Archaea	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	-	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
CMS3_k127_5761057_10	1459636.NTE_00005	1.261e-13	74.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5761057_9	1459636.NTE_00006	4.297e-20	91.0	arCOG07300@1|root,arCOG07300@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5761057_1	1459636.NTE_00007	1.451e-195	634.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
CMS3_k127_5761057_5	1229909.NSED_01010	1.159e-82	282.0	COG1801@1|root,arCOG04291@2157|Archaea,41T6J@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS3_k127_5761057_3	436308.Nmar_0694	6.416e-109	354.0	COG0638@1|root,arCOG00970@2157|Archaea,41SGS@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
CMS3_k127_5761057_0	436308.Nmar_0692	5.868e-250	775.0	COG0624@1|root,arCOG01110@2157|Archaea,41SAE@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS3_k127_5761057_2	1229909.NSED_03580	1.85e-146	468.0	COG0063@1|root,arCOG00018@2157|Archaea,41S8I@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase
CMS3_k127_5761057_7	436308.Nmar_0690	2.908e-70	241.0	COG2519@1|root,arCOG00978@2157|Archaea,41SEF@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
CMS3_k127_5767236_2	436308.Nmar_1358	3.339e-51	194.0	COG0491@1|root,arCOG00507@2157|Archaea	2157|Archaea	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS3_k127_5767236_1	1229909.NSED_02095	7.165e-57	200.0	COG3439@1|root,arCOG02761@2157|Archaea	2157|Archaea	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS3_k127_5767236_0	102129.Lepto7375DRAFT_2070	2.698e-76	265.0	COG0384@1|root,COG0384@2|Bacteria,1G0Y0@1117|Cyanobacteria,1H7VM@1150|Oscillatoriales	1117|Cyanobacteria	S	TIGRFAM phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
CMS3_k127_5771075_0	1229909.NSED_05420	0.0	1324.0	COG0574@1|root,arCOG01111@2157|Archaea,41SYV@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Pyruvate phosphate dikinase	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS3_k127_5771075_2	1229909.NSED_05415	5.687e-106	347.0	COG0149@1|root,arCOG01087@2157|Archaea,41SHT@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS3_k127_5771075_3	436308.Nmar_0949	1.015e-35	137.0	COG4095@1|root,arCOG05022@2157|Archaea,41SUZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Sugar efflux transporter for intercellular exchange	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv
CMS3_k127_5771075_1	436308.Nmar_0948	7.72e-266	822.0	COG0417@1|root,arCOG15272@2157|Archaea,41S91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA polymerase	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
CMS3_k127_5779702_7	1229909.NSED_06400	5.464e-158	501.0	COG3794@1|root,arCOG08764@1|root,arCOG02926@2157|Archaea,arCOG08764@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_5779702_2	436308.Nmar_1103	7.72e-292	900.0	COG0322@1|root,arCOG04753@2157|Archaea,41SX9@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TIGRFAM excinuclease ABC, C subunit	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
CMS3_k127_5779702_0	436308.Nmar_1104	0.0	1762.0	COG0178@1|root,arCOG04694@2157|Archaea,41T01@651137|Thaumarchaeota	651137|Thaumarchaeota	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS3_k127_5779702_1	1459636.NTE_02483	1.895e-296	921.0	COG0556@1|root,arCOG04748@2157|Archaea,41T0H@651137|Thaumarchaeota	651137|Thaumarchaeota	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS3_k127_5779702_8	1229909.NSED_06420	2.226e-108	353.0	COG3467@1|root,arCOG00520@2157|Archaea,41SJ5@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
CMS3_k127_5779702_9	436308.Nmar_1107	8.542e-48	175.0	arCOG10575@1|root,arCOG10575@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5779702_12	436308.Nmar_1108	1.217e-23	101.0	arCOG10576@1|root,arCOG10576@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5779702_3	436308.Nmar_1109	3.607e-228	707.0	COG2141@1|root,arCOG02410@2157|Archaea,41SBM@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Luciferase-like monooxygenase	-	-	-	ko:K14728	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
CMS3_k127_5779702_4	1229909.NSED_06440	1.022e-200	625.0	COG1454@1|root,arCOG00984@2157|Archaea,41SFC@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	ko:K18602	ko00720,ko01120,map00720,map01120	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS3_k127_5779702_5	436308.Nmar_1111	5.863e-193	610.0	COG2379@1|root,arCOG04170@2157|Archaea,41SJF@651137|Thaumarchaeota	651137|Thaumarchaeota	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS3_k127_5779702_13	1459636.NTE_01238	1.665e-23	102.0	COG1522@1|root,arCOG01117@2157|Archaea	1459636.NTE_01238|-	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5779702_10	1229909.NSED_06450	4.468e-38	143.0	arCOG08646@1|root,arCOG08646@2157|Archaea,41T7H@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5779702_6	436308.Nmar_1113	7.07e-178	560.0	COG1236@1|root,arCOG00545@2157|Archaea,41SYB@651137|Thaumarchaeota	651137|Thaumarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
CMS3_k127_5779702_11	436308.Nmar_1446	8.191e-29	115.0	COG3432@1|root,arCOG01055@2157|Archaea,41SST@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
CMS3_k127_5785890_0	1229909.NSED_06945	1.425e-151	481.0	COG0379@1|root,arCOG04459@2157|Archaea,41S6Y@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS3_k127_5785890_1	1229909.NSED_06950	1.195e-144	461.0	COG1712@1|root,arCOG00254@2157|Archaea,41SGA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
CMS3_k127_5785890_3	1229909.NSED_06960	7.222e-72	247.0	arCOG08716@1|root,arCOG08716@2157|Archaea	1229909.NSED_06960|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5785890_2	1229909.NSED_06965	2.426e-124	407.0	arCOG08777@1|root,arCOG10350@1|root,arCOG08777@2157|Archaea,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5785890_4	436308.Nmar_1010	1.603e-20	93.0	arCOG07473@1|root,arCOG07473@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5786581_19	1229909.NSED_02385	2.566e-12	67.0	arCOG07802@1|root,arCOG07802@2157|Archaea,41T6C@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS3_k127_5786581_12	1229909.NSED_02390	1.461e-76	260.0	arCOG08735@1|root,arCOG08735@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5786581_20	1459636.NTE_01145	6.402e-05	53.0	COG3359@1|root,arCOG03130@2157|Archaea,41STU@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H_2
CMS3_k127_5786581_17	1117314.PCIT_15101	7.301e-14	85.0	COG0739@1|root,COG3227@1|root,COG3291@1|root,COG0739@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,1PDUK@1224|Proteobacteria,1S8QS@1236|Gammaproteobacteria,2Q4BP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,Peptidase_M43
CMS3_k127_5786581_16	1227739.Hsw_1331	1.293e-45	186.0	COG3325@1|root,COG3325@2|Bacteria,4NNUM@976|Bacteroidetes,47PUW@768503|Cytophagia	976|Bacteroidetes	G	Glycoside hydrolase family	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
CMS3_k127_5786581_3	436308.Nmar_0475	6.306e-180	567.0	COG1131@1|root,arCOG00194@2157|Archaea,41TB9@651137|Thaumarchaeota	651137|Thaumarchaeota	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS3_k127_5786581_5	436308.Nmar_0476	1.085e-150	479.0	COG0842@1|root,arCOG01467@2157|Archaea,41SQQ@651137|Thaumarchaeota	651137|Thaumarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS3_k127_5786581_9	1229909.NSED_02410	1.163e-129	431.0	arCOG11445@1|root,arCOG11445@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5786581_10	1229909.NSED_02415	6.842e-108	352.0	COG1392@1|root,arCOG02640@2157|Archaea,41SKJ@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CMS3_k127_5786581_4	1229909.NSED_02420	1.86e-174	550.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CMS3_k127_5786581_1	1229909.NSED_02425	1.34e-187	590.0	COG3329@1|root,arCOG11287@2157|Archaea	2157|Archaea	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
CMS3_k127_5786581_14	1229909.NSED_02430	1.425e-47	172.0	arCOG11286@1|root,arCOG11286@2157|Archaea	2157|Archaea	S	Nitrogen regulatory protein P-II	-	-	-	-	-	-	-	-	-	-	-	-	P-II
CMS3_k127_5786581_13	436308.Nmar_0487	6.62e-51	181.0	COG0640@1|root,arCOG01680@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS3_k127_5786581_15	436308.Nmar_0488	1.604e-46	171.0	COG0394@1|root,arCOG04425@2157|Archaea,41T49@651137|Thaumarchaeota	651137|Thaumarchaeota	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS3_k127_5786581_11	1229909.NSED_02445	2.146e-101	334.0	COG0580@1|root,arCOG04431@2157|Archaea,41SJI@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Major Intrinsic Protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
CMS3_k127_5786581_0	436308.Nmar_0490	8.714e-235	730.0	COG0001@1|root,arCOG00918@2157|Archaea,41SDE@651137|Thaumarchaeota	651137|Thaumarchaeota	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS3_k127_5786581_6	436308.Nmar_0491	2.982e-149	477.0	COG0181@1|root,arCOG04299@2157|Archaea,41S6Z@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS3_k127_5786581_7	1229909.NSED_02465	4.177e-141	449.0	COG0007@1|root,arCOG00644@2157|Archaea,41S9J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
CMS3_k127_5786581_8	1229909.NSED_02470	1.667e-134	432.0	COG1587@1|root,arCOG02048@2157|Archaea,41SN2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS3_k127_5786581_18	1120998.AUFC01000039_gene3003	3.719e-13	74.0	COG0745@1|root,COG0745@2|Bacteria	1120998.AUFC01000039_gene3003|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5786581_2	436308.Nmar_0495	4.264e-183	573.0	COG0719@1|root,arCOG01715@2157|Archaea,41S5W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS3_k127_5797196_2	1229909.NSED_03045	3.64e-121	391.0	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
CMS3_k127_5797196_0	1229909.NSED_03040	4.013e-298	920.0	COG1384@1|root,arCOG00485@2157|Archaea,41SB4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
CMS3_k127_5797196_11	1229909.NSED_03035	7.383e-20	90.0	arCOG10985@1|root,arCOG10985@2157|Archaea,41T8V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5797196_7	436308.Nmar_0577	2.432e-47	183.0	arCOG08034@1|root,arCOG08034@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5797196_5	1229909.NSED_03025	2.991e-58	205.0	COG3576@1|root,arCOG00518@2157|Archaea,41T47@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS3_k127_5797196_10	1229909.NSED_03010	2.267e-27	111.0	arCOG08736@1|root,arCOG08736@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5797196_15	1216966.BAUC01000020_gene916	3.835e-07	57.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RYCY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	pgtA	-	-	ko:K08476	ko02020,map02020	M00503	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
CMS3_k127_5797196_14	1229909.NSED_08815	1.772e-07	54.0	COG5466@1|root,arCOG05278@2157|Archaea,41T8X@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
CMS3_k127_5797196_4	1229909.NSED_03000	3.709e-91	302.0	COG1528@1|root,arCOG01095@2157|Archaea	2157|Archaea	P	PFAM Ferritin, Dps family protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CMS3_k127_5797196_12	1353528.DT23_16980	3.233e-14	84.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,2UG54@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
CMS3_k127_5797196_9	1229909.NSED_08405	8.759e-37	153.0	arCOG07561@1|root,arCOG07561@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3,VWA
CMS3_k127_5797196_1	1229909.NSED_02995	1.058e-202	639.0	COG1914@1|root,arCOG04531@2157|Archaea	2157|Archaea	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,Nramp
CMS3_k127_5797196_3	1229909.NSED_02985	3.723e-93	308.0	COG2818@1|root,arCOG06523@2157|Archaea	2157|Archaea	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS3_k127_5797196_6	1229909.NSED_02980	3.922e-57	202.0	arCOG10529@1|root,arCOG10529@2157|Archaea,41T4K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_58071_4	436308.Nmar_0506	1.932e-22	96.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41T0Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_58071_1	1229909.NSED_02545	3.125e-106	347.0	COG1418@1|root,arCOG01860@2157|Archaea,41T2N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_58071_3	1229909.NSED_02550	1.271e-55	196.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_58071_0	1229909.NSED_02555	1.719e-187	588.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS3_k127_58071_2	1229909.NSED_02560	2.822e-67	230.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_5813953_0	436308.Nmar_0948	3.943e-231	720.0	COG0417@1|root,arCOG15272@2157|Archaea,41S91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA polymerase	-	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1
CMS3_k127_5813953_1	436308.Nmar_0947	3.993e-104	340.0	COG2131@1|root,arCOG01487@2157|Archaea,41SHS@651137|Thaumarchaeota	651137|Thaumarchaeota	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
CMS3_k127_5813953_2	436308.Nmar_0946	5.107e-12	66.0	arCOG08648@1|root,arCOG08648@2157|Archaea,41T9C@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5822343_2	436308.Nmar_1254	2.403e-81	273.0	COG1632@1|root,arCOG04209@2157|Archaea,41SND@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal protein L15E	-	-	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
CMS3_k127_5822343_3	436308.Nmar_1253	3.748e-77	267.0	arCOG08716@1|root,arCOG08716@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5822343_0	1229909.NSED_07020	1.763e-114	371.0	arCOG08717@1|root,arCOG08717@2157|Archaea,41SFQ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS3_k127_5822343_1	436308.Nmar_1251	2.544e-88	292.0	arCOG04006@1|root,arCOG04006@2157|Archaea,41SKF@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PBS lyase HEAT-like repeat	-	-	1.14.99.29	ko:K06072	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2
CMS3_k127_5822343_5	1229909.NSED_07010	2.415e-12	73.0	COG3794@1|root,arCOG10350@1|root,arCOG02926@2157|Archaea,arCOG10350@2157|Archaea	2157|Archaea	C	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Kazal_1
CMS3_k127_5822343_4	1229909.NSED_06400	3.199e-32	131.0	COG3794@1|root,arCOG08764@1|root,arCOG02926@2157|Archaea,arCOG08764@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_5853090_5	1229909.NSED_02790	6.417e-86	286.0	COG0169@1|root,arCOG01033@2157|Archaea,41S6G@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS3_k127_5853090_4	436308.Nmar_0551	2.336e-100	331.0	COG0169@1|root,arCOG02097@2157|Archaea,41SKU@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
CMS3_k127_5853090_2	1229909.NSED_02800	8.978e-195	610.0	COG1465@1|root,arCOG04353@2157|Archaea,41S88@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
CMS3_k127_5853090_3	1131266.ARWQ01000017_gene886	1.028e-135	436.0	COG1830@1|root,arCOG04044@2157|Archaea,41SCP@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroA'	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
CMS3_k127_5853090_1	1229909.NSED_02810	2.48e-219	682.0	COG1060@1|root,arCOG00656@2157|Archaea,41SCN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS3_k127_5853090_0	1229909.NSED_02815	3.966e-281	867.0	COG0043@1|root,arCOG01671@2157|Archaea,41S94@651137|Thaumarchaeota	651137|Thaumarchaeota	H	UbiD family decarboxylase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CMS3_k127_5853090_7	1459636.NTE_01710	1.19e-34	133.0	arCOG10521@1|root,arCOG10521@2157|Archaea,41T8A@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5853090_6	1229909.NSED_02820	9.854e-78	260.0	arCOG08652@1|root,arCOG08652@2157|Archaea,41SMZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5853090_8	436308.Nmar_0558	5.709e-12	66.0	arCOG08027@1|root,arCOG08027@2157|Archaea,41T8U@651137|Thaumarchaeota	2157|Archaea	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K22222	-	-	-	-	ko00000,ko04812	-	-	-	-
CMS3_k127_5882357_1	1229909.NSED_07450	1.379e-65	228.0	COG0475@1|root,arCOG01956@2157|Archaea	2157|Archaea	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Na_H_Exchanger
CMS3_k127_5882357_0	1229909.NSED_09500	2.109e-201	642.0	COG0668@1|root,arCOG01568@2157|Archaea,41SYX@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
CMS3_k127_5883146_4	1229909.NSED_08860	3.384e-95	316.0	COG1756@1|root,arCOG04122@2157|Archaea,41T2T@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	-	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
CMS3_k127_5883146_9	1229909.NSED_08855	2.271e-45	165.0	COG2023@1|root,arCOG04345@2157|Archaea,41STS@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	-	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
CMS3_k127_5883146_12	1229909.NSED_05805	3.035e-27	112.0	COG0168@1|root,COG0517@1|root,arCOG00606@2157|Archaea,arCOG04145@2157|Archaea,41SZ8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	CBS domain	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	CBS,TrkH
CMS3_k127_5883146_3	1144275.COCOR_00573	2.334e-102	349.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS3_k127_5883146_5	436308.Nmar_1624	1.321e-83	278.0	COG2238@1|root,arCOG01344@2157|Archaea,41SK1@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	-	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
CMS3_k127_5883146_11	1229909.NSED_08785	1.788e-29	119.0	COG2118@1|root,arCOG04179@2157|Archaea,41SR0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
CMS3_k127_5883146_0	1229909.NSED_08780	1.936e-230	714.0	COG0604@1|root,arCOG01458@2157|Archaea,41SZ9@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS3_k127_5883146_2	436308.Nmar_1621	2.225e-141	453.0	COG2301@1|root,arCOG00760@2157|Archaea,41S6F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS3_k127_5883146_6	436308.Nmar_1618	6.222e-76	261.0	arCOG05137@1|root,arCOG05137@2157|Archaea	2157|Archaea	S	TPR repeat	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	TPR_1,TPR_8
CMS3_k127_5883146_10	436308.Nmar_1591	1.504e-33	135.0	arCOG07442@1|root,arCOG07442@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5883146_7	1229909.NSED_00550	3.26e-69	237.0	arCOG10592@1|root,arCOG10592@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5883146_13	436308.Nmar_1589	1.576e-22	98.0	arCOG10591@1|root,arCOG10591@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5883146_1	1229909.NSED_00560	5.024e-177	557.0	COG0109@1|root,arCOG00479@2157|Archaea,41SFH@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS3_k127_5883146_8	436308.Nmar_1587	2.94e-66	228.0	COG1522@1|root,arCOG01580@2157|Archaea,41SKI@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
CMS3_k127_5887277_2	436308.Nmar_0341	3.583e-07	51.0	COG1104@1|root,arCOG00066@2157|Archaea,41SB1@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS3_k127_5887277_1	436308.Nmar_0342	3.497e-72	252.0	arCOG08643@1|root,arCOG08716@1|root,arCOG08643@2157|Archaea,arCOG08716@2157|Archaea,41T3A@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_5887277_0	436308.Nmar_0343	6.252e-101	336.0	arCOG08643@1|root,arCOG08716@1|root,arCOG08643@2157|Archaea,arCOG08716@2157|Archaea,41T4R@651137|Thaumarchaeota	651137|Thaumarchaeota	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_59145_1	1229909.NSED_03795	2.031e-203	638.0	arCOG08801@1|root,arCOG08801@2157|Archaea	2157|Archaea	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_59145_2	1229909.NSED_03790	7.03e-186	593.0	COG0277@1|root,arCOG00337@2157|Archaea,41T0E@651137|Thaumarchaeota	651137|Thaumarchaeota	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS3_k127_59145_7	1131266.ARWQ01000001_gene1219	1.981e-23	104.0	arCOG08777@1|root,arCOG08647@2157|Archaea,41SNX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_59145_6	436308.Nmar_0733	1.367e-23	100.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41TA2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_59145_5	436308.Nmar_0731	4.06e-34	134.0	arCOG08757@1|root,arCOG08757@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_59145_3	436308.Nmar_0729	1.017e-97	323.0	COG0605@1|root,arCOG04147@2157|Archaea,41S6C@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS3_k127_59145_4	436308.Nmar_0727	2.211e-39	154.0	arCOG08797@1|root,arCOG08797@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_59145_0	436308.Nmar_0726	0.0	1014.0	COG0553@1|root,arCOG00883@2157|Archaea,41T0G@651137|Thaumarchaeota	651137|Thaumarchaeota	K	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
CMS3_k127_59145_8	1229909.NSED_07455	1.305e-20	96.0	COG1846@1|root,arCOG03748@2157|Archaea	2157|Archaea	K	RNA secondary structure unwinding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45,MarR_2,TrmB
CMS3_k127_59145_9	436308.Nmar_0825	3.645e-20	91.0	COG0330@1|root,arCOG01915@2157|Archaea,41SYP@651137|Thaumarchaeota	651137|Thaumarchaeota	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS3_k127_598050_5	436308.Nmar_1410	1.678e-89	297.0	COG1718@1|root,arCOG01180@2157|Archaea,41T2X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Serine threonine protein kinase involved in cell cycle control	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
CMS3_k127_598050_9	1459636.NTE_00633	1.511e-54	197.0	COG1094@1|root,arCOG04150@2157|Archaea,41SNG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	K homology RNA-binding domain	-	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
CMS3_k127_598050_0	436308.Nmar_1408	0.0	1051.0	COG1389@1|root,arCOG01165@2157|Archaea,41SJ2@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
CMS3_k127_598050_2	1229909.NSED_07730	1.339e-226	704.0	COG1697@1|root,arCOG04143@2157|Archaea,41SQF@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
CMS3_k127_598050_6	436308.Nmar_1406	2.446e-81	273.0	COG0071@1|root,arCOG01833@2157|Archaea	2157|Archaea	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_598050_8	436308.Nmar_1360	1.099e-60	218.0	COG2968@1|root,arCOG04715@2157|Archaea,41T6R@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CMS3_k127_598050_12	1229909.NSED_07615	2.364e-16	81.0	arCOG08701@1|root,arCOG08701@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_598050_11	436308.Nmar_1404	8.34e-44	162.0	arCOG08702@1|root,arCOG08702@2157|Archaea,41ST2@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_598050_7	1229909.NSED_07605	1.799e-69	237.0	arCOG08703@1|root,arCOG08703@2157|Archaea,41SS0@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_598050_10	1229909.NSED_07600	1.274e-44	163.0	arCOG08704@1|root,arCOG08704@2157|Archaea,41STG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_598050_3	436308.Nmar_1401	2.012e-149	475.0	COG0005@1|root,arCOG01327@2157|Archaea,41SDR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS3_k127_598050_4	1229909.NSED_07590	4.28e-93	308.0	COG0503@1|root,arCOG00030@2157|Archaea,41SMR@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS3_k127_598050_1	1229909.NSED_07585	3.069e-244	769.0	arCOG08705@1|root,arCOG08705@2157|Archaea,41SXV@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6011244_4	436308.Nmar_0434	1.575e-33	130.0	COG1997@1|root,arCOG04208@2157|Archaea,41SUE@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Ribosomal L37ae protein family	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
CMS3_k127_6011244_2	1229909.NSED_05085	5.372e-62	220.0	COG1468@1|root,arCOG00786@2157|Archaea	2157|Archaea	L	TIGRFAM CRISPR-associated protein Cas4	-	-	3.1.12.1	ko:K03466,ko:K07464,ko:K15342,ko:K19465	-	-	-	-	ko00000,ko01000,ko02048,ko03029,ko03036,ko03400	3.A.12	-	-	Cas_Cas4,FtsK_SpoIIIE,PDDEXK_1
CMS3_k127_6011244_3	436308.Nmar_0436	1.586e-41	156.0	COG1382@1|root,arCOG01342@2157|Archaea,41SPD@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
CMS3_k127_6011244_0	1229909.NSED_02270	3.334e-120	389.0	COG1948@1|root,arCOG04206@2157|Archaea,41SIH@651137|Thaumarchaeota	651137|Thaumarchaeota	L	ERCC4 domain	-	-	-	ko:K10848	ko03420,ko03460,map03420,map03460	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	ERCC4,HHH_5
CMS3_k127_6011244_1	1229909.NSED_02275	5.826e-76	257.0	COG1439@1|root,arCOG00721@2157|Archaea,41SPQ@651137|Thaumarchaeota	651137|Thaumarchaeota	V	PIN domain of ribonuclease	-	-	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
CMS3_k127_6018067_2	1229909.NSED_02560	2.058e-67	230.0	COG0373@1|root,arCOG01036@2157|Archaea,41SDM@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	-	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS3_k127_6018067_0	1229909.NSED_02555	1.415e-185	583.0	COG0113@1|root,arCOG04300@2157|Archaea,41SET@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS3_k127_6018067_3	1229909.NSED_02550	9.271e-56	196.0	arCOG08763@1|root,arCOG08763@2157|Archaea,41SWC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6018067_1	436308.Nmar_0507	5.872e-106	346.0	COG1418@1|root,arCOG01860@2157|Archaea,41T2N@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_6018067_4	436308.Nmar_0506	3.301e-14	72.0	arCOG03119@1|root,arCOG03119@2157|Archaea,41T0Y@651137|Thaumarchaeota	651137|Thaumarchaeota	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6042129_2	706587.Desti_2409	4.804e-51	184.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MQWH@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS3_k127_6042129_0	436308.Nmar_0232	1.66e-65	225.0	COG1371@1|root,arCOG04055@2157|Archaea,41SU0@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
CMS3_k127_6042129_1	436308.Nmar_0231	1.352e-61	219.0	arCOG06534@1|root,arCOG06534@2157|Archaea	2157|Archaea	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
CMS3_k127_6050220_3	436308.Nmar_0589	1.127e-19	91.0	arCOG05565@1|root,arCOG05565@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6050220_2	1229909.NSED_09385	1.248e-22	97.0	arCOG08748@1|root,arCOG08748@2157|Archaea,41SV7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6050220_4	1229909.NSED_09390	3.556e-17	81.0	arCOG08748@1|root,arCOG08748@2157|Archaea,41TAF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6050220_1	436308.Nmar_1760	7.655e-90	297.0	COG2453@1|root,arCOG03413@2157|Archaea,41SK5@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Dual specificity phosphatase, catalytic domain	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	DSPc
CMS3_k127_6050220_0	1131266.ARWQ01000010_gene30	1.171e-183	578.0	COG1180@1|root,arCOG00946@2157|Archaea,41SBZ@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
CMS3_k127_6074748_4	1229909.NSED_00745	1.284e-92	305.0	COG0107@1|root,arCOG00617@2157|Archaea,41S9A@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_6074748_1	1229909.NSED_00740	6.116e-124	399.0	COG0106@1|root,arCOG00618@2157|Archaea,41SIG@651137|Thaumarchaeota	651137|Thaumarchaeota	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS3_k127_6074748_2	1229909.NSED_00735	1.048e-115	376.0	COG0118@1|root,arCOG00089@2157|Archaea,41SY2@651137|Thaumarchaeota	651137|Thaumarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS3_k127_6074748_3	1229909.NSED_00730	4.062e-108	351.0	COG0131@1|root,arCOG04398@2157|Archaea,41SGY@651137|Thaumarchaeota	651137|Thaumarchaeota	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS3_k127_6074748_0	1229909.NSED_00725	1.332e-166	527.0	COG0546@1|root,arCOG04692@2157|Archaea,41SJ6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
CMS3_k127_6074748_5	1229909.NSED_00720	4.907e-13	68.0	COG0079@1|root,arCOG04273@2157|Archaea,41SGB@651137|Thaumarchaeota	651137|Thaumarchaeota	E	PFAM Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS3_k127_610978_13	1131266.ARWQ01000009_gene934	8.518e-34	132.0	COG2429@1|root,arCOG04202@2157|Archaea,41SHK@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity	gch3	-	3.5.4.29	ko:K08096	ko00740,ko01100,map00740,map01100	-	R07306	RC01790	ko00000,ko00001,ko01000	-	-	-	GCH_III
CMS3_k127_610978_2	436308.Nmar_1613	5.454e-183	579.0	COG0402@1|root,arCOG00692@2157|Archaea,41S61@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS3_k127_610978_10	1459636.NTE_03545	1.682e-49	184.0	COG1985@1|root,arCOG01484@2157|Archaea,41SK2@651137|Thaumarchaeota	651137|Thaumarchaeota	H	RibD C-terminal domain	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
CMS3_k127_610978_14	1229909.NSED_08720	9.112e-22	96.0	arCOG10596@1|root,arCOG10596@2157|Archaea,41T8F@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_610978_6	1229909.NSED_08715	1.608e-86	289.0	COG3945@1|root,arCOG01471@2157|Archaea,41T3D@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Hemerythrin HHE cation binding	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS3_k127_610978_0	1229909.NSED_08705	2.932e-277	856.0	COG1012@1|root,arCOG01252@2157|Archaea,41T0F@651137|Thaumarchaeota	651137|Thaumarchaeota	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135,ko:K18601	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS3_k127_610978_4	436308.Nmar_1607	2.431e-100	328.0	COG1675@1|root,arCOG04270@2157|Archaea,41SJ8@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes	tfe	-	-	ko:K03136	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIE_alpha
CMS3_k127_610978_8	1459636.NTE_00448	2.088e-59	210.0	COG1303@1|root,arCOG01857@2157|Archaea,41SIR@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	-	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
CMS3_k127_610978_3	1229909.NSED_08690	4.033e-174	552.0	COG2262@1|root,arCOG00353@2157|Archaea,41SD4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS3_k127_610978_1	436308.Nmar_1604	1.663e-187	589.0	COG0704@1|root,arCOG00318@2157|Archaea,41SC5@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Phosphate uptake regulator	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
CMS3_k127_610978_7	436308.Nmar_1603	2.079e-67	232.0	COG1370@1|root,arCOG00991@2157|Archaea,41SP1@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Patch-forming domain C2 of tRNA-guanine transglycosylase	-	-	-	ko:K07398	-	-	-	-	ko00000	-	-	-	PUA,TGT_C2
CMS3_k127_610978_9	1229909.NSED_08675	2.049e-54	192.0	COG1308@1|root,arCOG04061@2157|Archaea,41SNN@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
CMS3_k127_610978_12	436308.Nmar_1601	1.429e-40	152.0	COG2811@1|root,arCOG03363@2157|Archaea,41TA7@651137|Thaumarchaeota	651137|Thaumarchaeota	C	H subunit	-	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
CMS3_k127_610978_5	436308.Nmar_1600	2.748e-98	324.0	arCOG03142@1|root,arCOG03142@2157|Archaea,41T78@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_610978_11	1229909.NSED_08655	4.537e-47	173.0	arCOG08662@1|root,arCOG08662@2157|Archaea,41SQG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_613559_0	1229909.NSED_05445	3.25e-55	197.0	COG0589@1|root,arCOG02053@2157|Archaea,41T8H@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS3_k127_613559_1	436308.Nmar_0333	3.549e-25	122.0	arCOG08778@1|root,arCOG08778@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6186490_2	436308.Nmar_0374	3.214e-06	49.0	COG2058@1|root,arCOG04287@2157|Archaea,41SP0@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	-	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
CMS3_k127_6186490_1	1131266.ARWQ01000001_gene1150	4.936e-91	303.0	COG2860@1|root,arCOG04641@2157|Archaea,41SIS@651137|Thaumarchaeota	651137|Thaumarchaeota	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
CMS3_k127_6186490_0	436308.Nmar_0381	9.853e-125	403.0	COG0244@1|root,arCOG04288@2157|Archaea,41S9R@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS3_k127_6229649_8	662479.C440_13759	0.000314	51.0	COG5608@1|root,arCOG03787@2157|Archaea,2XUH8@28890|Euryarchaeota,23SA8@183963|Halobacteria	183963|Halobacteria	V	COG5608 Conserved secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
CMS3_k127_6229649_6	436308.Nmar_1018	4.253e-38	145.0	arCOG10569@1|root,arCOG10569@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6229649_0	1229909.NSED_06005	7.803e-135	433.0	arCOG03042@1|root,arCOG03042@2157|Archaea	2157|Archaea	KLT	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
CMS3_k127_6229649_2	1229909.NSED_06010	1.19e-100	332.0	arCOG08737@1|root,arCOG08737@2157|Archaea,41T1W@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6229649_7	1229909.NSED_06015	4.621e-32	128.0	arCOG08738@1|root,arCOG08738@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
CMS3_k127_6229649_3	1229909.NSED_06020	4.826e-82	274.0	COG1917@1|root,arCOG03444@2157|Archaea,41SV4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_6229649_5	1229909.NSED_06025	1.932e-57	201.0	COG0662@1|root,arCOG03003@2157|Archaea	2157|Archaea	G	PFAM Cupin 2, conserved barrel domain protein	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Cupin_2
CMS3_k127_6229649_1	1229909.NSED_06030	2.637e-119	386.0	COG0484@1|root,COG1141@1|root,arCOG00349@2157|Archaea,arCOG02846@2157|Archaea,41ST0@651137|Thaumarchaeota	651137|Thaumarchaeota	CO	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,Fer4_13
CMS3_k127_6229649_4	1229909.NSED_06035	1.218e-58	205.0	COG0537@1|root,arCOG00419@2157|Archaea,41SNI@651137|Thaumarchaeota	651137|Thaumarchaeota	F	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS3_k127_6236156_3	436308.Nmar_1360	8.439e-59	210.0	COG2968@1|root,arCOG04715@2157|Archaea,41T6R@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CMS3_k127_6236156_2	436308.Nmar_1359	1.203e-73	254.0	COG0640@1|root,arCOG01686@2157|Archaea	2157|Archaea	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_6236156_0	1229909.NSED_02115	2.68e-154	494.0	COG1503@1|root,arCOG01742@2157|Archaea	1229909.NSED_02115|-	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
CMS3_k127_6236156_4	436308.Nmar_1454	5.769e-16	79.0	arCOG14602@1|root,arCOG14602@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6236156_1	1229909.NSED_01975	2.639e-97	325.0	COG1475@1|root,arCOG01875@2157|Archaea	2157|Archaea	K	PFAM ParB domain protein nuclease	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS3_k127_6236156_5	436308.Nmar_0251	1.013e-10	64.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CMS3_k127_6257354_0	436308.Nmar_1267	1.436e-303	937.0	COG0294@1|root,COG1410@1|root,arCOG02029@2157|Archaea,arCOG02817@2157|Archaea,41SXT@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
CMS3_k127_6257354_1	1229909.NSED_07095	1.213e-109	359.0	COG0685@1|root,arCOG00475@2157|Archaea,41SNK@651137|Thaumarchaeota	651137|Thaumarchaeota	E	cytochrome-c peroxidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6257354_2	436308.Nmar_1265	1.98e-83	280.0	COG0494@1|root,arCOG01072@2157|Archaea,41STX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_6257354_4	436308.Nmar_1264	1.637e-21	94.0	COG2167@1|root,arCOG04177@2157|Archaea,41SUT@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	-	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
CMS3_k127_6257354_3	436308.Nmar_1263	1.744e-44	165.0	COG2097@1|root,arCOG04473@2157|Archaea,41STQ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the ribosomal protein L31e family	rpl31e	-	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
CMS3_k127_6320227_4	436308.Nmar_0797	9.209e-31	121.0	COG0094@1|root,arCOG04092@2157|Archaea,41SJP@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS3_k127_6320227_3	436308.Nmar_0796	3.082e-32	126.0	COG0199@1|root,arCOG00782@2157|Archaea,41SW8@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS3_k127_6320227_0	436308.Nmar_0794	1.337e-86	289.0	COG0097@1|root,arCOG04090@2157|Archaea,41SJG@651137|Thaumarchaeota	651137|Thaumarchaeota	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS3_k127_6320227_1	436308.Nmar_0793	1.124e-45	166.0	arCOG08710@1|root,arCOG08710@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6320227_2	436308.Nmar_0792	4.091e-42	155.0	arCOG08711@1|root,arCOG08711@2157|Archaea,41T4I@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6320227_5	1229909.NSED_04395	3.708e-17	81.0	arCOG11516@1|root,arCOG11516@2157|Archaea,41T9Y@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6686000_0	1229909.NSED_05425	2.622e-107	348.0	COG3620@1|root,arCOG00608@2157|Archaea,41SJR@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HTH_3
CMS3_k127_6686000_1	1131266.ARWQ01000029_gene982	6.722e-104	357.0	arCOG08793@1|root,arCOG08793@2157|Archaea,41TBC@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6734911_7	1229909.NSED_09900	3.034e-54	192.0	COG1786@1|root,arCOG04279@2157|Archaea,41SPA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
CMS3_k127_6734911_1	436308.Nmar_0053	1.696e-209	655.0	COG1679@1|root,arCOG04278@2157|Archaea,41SBC@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
CMS3_k127_6734911_5	436308.Nmar_0052	2.854e-111	362.0	COG0177@1|root,arCOG00459@2157|Archaea,41SFM@651137|Thaumarchaeota	651137|Thaumarchaeota	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS3_k127_6734911_0	1229909.NSED_09875	4.896e-224	696.0	COG2046@1|root,arCOG04191@2157|Archaea,41SER@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
CMS3_k127_6734911_4	1229909.NSED_09870	3.491e-112	366.0	COG0175@1|root,arCOG00124@2157|Archaea,41S9Q@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS3_k127_6734911_3	436308.Nmar_0048	2.587e-157	504.0	COG0301@1|root,arCOG00038@2157|Archaea,41ST5@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6734911_2	436308.Nmar_0047	9.052e-204	640.0	COG1819@1|root,arCOG01393@2157|Archaea,41SZK@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6734911_9	436308.Nmar_0046	6.771e-45	164.0	arCOG08817@1|root,arCOG08817@2157|Archaea,41SV5@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6734911_6	436308.Nmar_0045	2.068e-58	205.0	arCOG10514@1|root,arCOG10514@2157|Archaea,41STR@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6734911_8	1229909.NSED_09845	7.351e-47	169.0	COG0300@1|root,arCOG01263@2157|Archaea,41SXQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS3_k127_6738498_1	1229909.NSED_01500	3.016e-130	419.0	COG0008@1|root,arCOG04302@2157|Archaea,41S5V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CMS3_k127_6738498_0	436308.Nmar_0310	2.18e-155	494.0	COG0179@1|root,arCOG00235@2157|Archaea,41S5K@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS3_k127_6738498_3	1229909.NSED_01490	4.163e-85	295.0	COG0454@1|root,arCOG00845@2157|Archaea,41T5Q@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS3_k127_6738498_4	436308.Nmar_0308	1.978e-53	188.0	COG2146@1|root,arCOG02852@2157|Archaea,41SSE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
CMS3_k127_6738498_5	436308.Nmar_0307	3.788e-40	149.0	COG1698@1|root,arCOG04308@2157|Archaea,41SRP@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Belongs to the UPF0147 family	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
CMS3_k127_6738498_2	1229909.NSED_01475	9.606e-115	374.0	COG0500@1|root,arCOG01631@2157|Archaea,41SJC@651137|Thaumarchaeota	651137|Thaumarchaeota	Q	RNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DOT1
CMS3_k127_6738498_6	1229909.NSED_01470	2.527e-14	73.0	arCOG08781@1|root,arCOG08781@2157|Archaea,41SVY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751141_0	1229909.NSED_00615	6.129e-196	615.0	COG1001@1|root,arCOG00693@2157|Archaea,41SZH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
CMS3_k127_6751141_2	1229909.NSED_00610	1.587e-50	180.0	COG1631@1|root,arCOG04109@2157|Archaea,41SQZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl44e	-	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
CMS3_k127_6751141_4	933801.Ahos_1251	1.555e-11	66.0	COG2051@1|root,arCOG04108@2157|Archaea,2XR0Y@28889|Crenarchaeota	28889|Crenarchaeota	J	PFAM ribosomal protein	rps27e	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
CMS3_k127_6751141_1	1229909.NSED_00600	4.062e-71	246.0	COG2266@1|root,arCOG01871@2157|Archaea,41SRI@651137|Thaumarchaeota	651137|Thaumarchaeota	M	MobA-like NTP transferase domain	-	-	2.7.7.62	ko:K19712	ko00860,ko01100,map00860,map01100	-	R05222	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS3_k127_6751141_3	1131266.ARWQ01000009_gene958	3.755e-18	85.0	COG0368@1|root,arCOG04338@2157|Archaea,41SI6@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
CMS3_k127_6751155_19	436308.Nmar_1432	3.005e-30	120.0	COG2036@1|root,arCOG02144@2157|Archaea,41T91@651137|Thaumarchaeota	651137|Thaumarchaeota	L	transcription factor (CBF NF-Y)	-	-	-	-	-	-	-	-	-	-	-	-	CBFD_NFYB_HMF
CMS3_k127_6751155_5	436308.Nmar_1431	1.115e-110	362.0	COG0084@1|root,arCOG00891@2157|Archaea,41SGP@651137|Thaumarchaeota	651137|Thaumarchaeota	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS3_k127_6751155_21	1229909.NSED_07840	2.387e-19	92.0	COG1383@1|root,arCOG01885@2157|Archaea,41SUH@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ribosomal protein	-	-	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
CMS3_k127_6751155_6	436308.Nmar_1429	4.933e-95	317.0	COG1617@1|root,COG1977@1|root,arCOG00536@2157|Archaea,arCOG02197@2157|Archaea,41SSW@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Kinase binding protein CGI-121	-	-	-	-	-	-	-	-	-	-	-	-	CGI-121,ThiS
CMS3_k127_6751155_13	1131266.ARWQ01000018_gene768	1.018e-46	174.0	COG1818@1|root,arCOG00084@2157|Archaea,41SNW@651137|Thaumarchaeota	651137|Thaumarchaeota	S	THUMP domain	-	-	-	ko:K06963	-	-	-	-	ko00000,ko03016	-	-	-	THUMP
CMS3_k127_6751155_8	436308.Nmar_1427	1.44e-74	255.0	COG0009@1|root,arCOG01952@2157|Archaea,41SPF@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Sua5 YciO YrdC YwlC family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
CMS3_k127_6751155_12	436308.Nmar_1426	7.188e-47	169.0	COG3432@1|root,arCOG01055@2157|Archaea,41SUJ@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
CMS3_k127_6751155_4	436308.Nmar_1425	8.084e-115	372.0	arCOG08771@1|root,arCOG08771@2157|Archaea,41SNZ@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751155_16	436308.Nmar_1424	9.544e-33	127.0	arCOG08687@1|root,arCOG08687@2157|Archaea,41SVF@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751155_17	1229909.NSED_00230	3.097e-32	131.0	arCOG10515@1|root,arCOG10515@2157|Archaea,41TAP@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751155_11	1229909.NSED_07805	5.725e-48	172.0	arCOG10584@1|root,arCOG10584@2157|Archaea,41SV6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Bacterial Fe(2+) trafficking	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
CMS3_k127_6751155_9	1229909.NSED_07800	1.408e-61	215.0	arCOG08772@1|root,arCOG08772@2157|Archaea,41SSX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751155_1	1229909.NSED_07795	4.128e-190	596.0	COG0104@1|root,arCOG04387@2157|Archaea,41SCA@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS3_k127_6751155_14	1459636.NTE_00654	1.202e-41	161.0	arCOG08773@1|root,arCOG08773@2157|Archaea,41SNY@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751155_3	1229909.NSED_07785	1.346e-132	425.0	COG0284@1|root,arCOG00081@2157|Archaea,41SMN@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS3_k127_6751155_18	444157.Tneu_1020	1.16e-31	129.0	COG0494@1|root,arCOG01078@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS3_k127_6751155_2	436308.Nmar_1416	3.017e-143	456.0	COG0020@1|root,arCOG01532@2157|Archaea,41S8J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	-	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
CMS3_k127_6751155_0	1229909.NSED_07770	7.022e-196	615.0	COG2237@1|root,arCOG04151@2157|Archaea,41SA3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
CMS3_k127_6751155_10	436308.Nmar_1414	2.011e-54	196.0	arCOG08774@1|root,arCOG08774@2157|Archaea,41T7U@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751155_20	436308.Nmar_1413	3.462e-24	101.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6751155_7	436308.Nmar_1412	1.435e-79	266.0	COG1601@1|root,arCOG01640@2157|Archaea,41STZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor	-	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	eIF-5_eIF-2B
CMS3_k127_6751155_15	436308.Nmar_1411	2.559e-38	145.0	COG2412@1|root,arCOG04051@2157|Archaea,41SS6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
CMS3_k127_6751155_22	1229909.NSED_07745	3.939e-09	58.0	COG1718@1|root,arCOG01180@2157|Archaea,41T2X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Serine threonine protein kinase involved in cell cycle control	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
CMS3_k127_6777383_0	1229909.NSED_04905	1.073e-156	499.0	COG3221@1|root,arCOG01805@2157|Archaea,41SWY@651137|Thaumarchaeota	651137|Thaumarchaeota	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS3_k127_6777383_3	436308.Nmar_0876	3.135e-50	181.0	COG0640@1|root,arCOG03067@2157|Archaea,41T62@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6777383_2	1229909.NSED_04915	1.301e-53	190.0	COG0640@1|root,arCOG03067@2157|Archaea,41T4C@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS3_k127_6777383_1	436308.Nmar_0878	7.713e-78	263.0	arCOG06353@1|root,arCOG06353@2157|Archaea,41SI1@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
CMS3_k127_6808503_6	1229909.NSED_07745	1.635e-20	91.0	COG1718@1|root,arCOG01180@2157|Archaea,41T2X@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Serine threonine protein kinase involved in cell cycle control	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
CMS3_k127_6808503_4	1229909.NSED_07750	1.055e-41	154.0	COG2412@1|root,arCOG04051@2157|Archaea,41SS6@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
CMS3_k127_6808503_1	1229909.NSED_07755	2.3e-87	288.0	COG1601@1|root,arCOG01640@2157|Archaea,41STZ@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Translation initiation factor	-	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	eIF-5_eIF-2B
CMS3_k127_6808503_5	1229909.NSED_07760	3.541e-25	104.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6808503_2	1229909.NSED_07765	3.521e-74	252.0	arCOG08774@1|root,arCOG08774@2157|Archaea,41T7U@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6808503_0	1229909.NSED_07770	3.054e-208	653.0	COG2237@1|root,arCOG04151@2157|Archaea,41SA3@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
CMS3_k127_6808503_3	436308.Nmar_1416	5.749e-47	169.0	COG0020@1|root,arCOG01532@2157|Archaea,41S8J@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	-	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
CMS3_k127_6859358_2	436308.Nmar_1575	1.473e-42	156.0	arCOG08720@1|root,arCOG08720@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF2024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2024
CMS3_k127_6859358_1	436308.Nmar_1576	8.905e-140	448.0	COG1940@1|root,arCOG04280@2157|Archaea,41SWX@651137|Thaumarchaeota	651137|Thaumarchaeota	K	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
CMS3_k127_6859358_0	436308.Nmar_1577	3.037e-308	948.0	COG0459@1|root,arCOG01257@2157|Archaea,41T11@651137|Thaumarchaeota	651137|Thaumarchaeota	O	TCP-1/cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
CMS3_k127_6862275_0	1229909.NSED_00695	1.321e-148	472.0	COG1571@1|root,arCOG01115@2157|Archaea,41S9G@651137|Thaumarchaeota	651137|Thaumarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	-	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743
CMS3_k127_6862275_1	1229909.NSED_00700	1.003e-111	363.0	COG2133@1|root,arCOG02796@2157|Archaea,41S7F@651137|Thaumarchaeota	651137|Thaumarchaeota	G	Glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS3_k127_6884919_6	1229909.NSED_06840	6.742e-24	103.0	COG4263@1|root,arCOG06217@2157|Archaea	2157|Archaea	C	Cytochrome C oxidase, subunit II	nosZ	-	1.7.2.4,1.9.3.1	ko:K00376,ko:K02275	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00529	R00081,R02804	RC00016,RC02861	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1,TAT_signal
CMS3_k127_6884919_2	1229909.NSED_09670	8.478e-49	184.0	COG0652@1|root,arCOG04767@2157|Archaea,41T0W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS3_k127_6884919_1	436308.Nmar_0408	1.229e-69	239.0	arCOG08670@1|root,arCOG08670@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DM13
CMS3_k127_6884919_0	1229909.NSED_06535	1.677e-112	374.0	arCOG03042@1|root,arCOG03042@2157|Archaea	2157|Archaea	KLT	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
CMS3_k127_6884919_3	1229909.NSED_07295	7.866e-36	138.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2226,P-II
CMS3_k127_6884919_5	1229909.NSED_02930	1.247e-26	113.0	arCOG08754@1|root,arCOG08754@2157|Archaea	1229909.NSED_02930|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6902535_0	1229909.NSED_03535	1.492e-28	118.0	COG0347@1|root,arCOG02305@2157|Archaea	2157|Archaea	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS3_k127_6902535_2	373994.Riv7116_2486	3.124e-15	91.0	COG1680@1|root,COG1680@2|Bacteria,1G82D@1117|Cyanobacteria,1HNIT@1161|Nostocales	1117|Cyanobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6902535_1	436308.Nmar_0333	8.619e-17	96.0	arCOG08778@1|root,arCOG08778@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6902535_3	553178.CAPGI0001_2409	1.478e-10	75.0	COG2374@1|root,COG3391@1|root,COG4935@1|root,COG5276@1|root,COG2374@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,COG5276@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,1ER48@1016|Capnocytophaga	976|Bacteroidetes	O	Thrombospondin type 3	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
CMS3_k127_6902743_1	436308.Nmar_0579	5.463e-159	504.0	COG1243@1|root,arCOG01361@2157|Archaea,41S9N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Histone acetyltransferase	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
CMS3_k127_6902743_0	1229909.NSED_03055	6.734e-211	660.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS3_k127_6902743_2	1229909.NSED_03060	1.579e-100	329.0	COG0150@1|root,arCOG00639@2157|Archaea,41SEE@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS3_k127_6902835_0	1229909.NSED_07855	2.632e-46	170.0	COG3794@1|root,arCOG02926@2157|Archaea,41TAN@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS3_k127_6902835_1	1229909.NSED_00515	1.414e-44	169.0	arCOG07810@1|root,arCOG07810@2157|Archaea,41T4X@651137|Thaumarchaeota	2157|Archaea	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS3_k127_693125_4	1229909.NSED_06025	2.389e-20	92.0	COG0662@1|root,arCOG03003@2157|Archaea	2157|Archaea	G	PFAM Cupin 2, conserved barrel domain protein	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Cupin_2
CMS3_k127_693125_2	436308.Nmar_1022	1.564e-66	229.0	COG1917@1|root,arCOG03444@2157|Archaea,41SV4@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS3_k127_693125_3	1229909.NSED_06015	1.441e-39	151.0	arCOG08738@1|root,arCOG08738@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
CMS3_k127_693125_1	1229909.NSED_06010	1.476e-93	312.0	arCOG08737@1|root,arCOG08737@2157|Archaea,41T1W@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_693125_0	1229909.NSED_06005	2.511e-122	397.0	arCOG03042@1|root,arCOG03042@2157|Archaea	2157|Archaea	KLT	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
CMS3_k127_6957088_3	1229909.NSED_09900	2.438e-22	97.0	COG1786@1|root,arCOG04279@2157|Archaea,41SPA@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
CMS3_k127_6957088_0	1131266.ARWQ01000010_gene27	1.478e-78	267.0	COG2078@1|root,arCOG01336@2157|Archaea,41SMG@651137|Thaumarchaeota	651137|Thaumarchaeota	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
CMS3_k127_6957088_2	1229909.NSED_01055	6.766e-42	160.0	COG1656@1|root,arCOG04290@2157|Archaea,41T65@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
CMS3_k127_6957088_1	436308.Nmar_0055	1.972e-71	243.0	COG1293@1|root,arCOG01695@2157|Archaea,41SB0@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
CMS3_k127_6961371_3	1047013.AQSP01000132_gene1692	2.316e-27	123.0	COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria	2|Bacteria	M	Male sterility protein	-	-	1.1.1.219,5.1.3.26	ko:K00091,ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS3_k127_6961371_1	436308.Nmar_0982	6.976e-59	206.0	COG1832@1|root,arCOG04227@2157|Archaea,41SMT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS3_k127_6961371_2	436308.Nmar_0981	1.513e-40	153.0	arCOG05491@1|root,arCOG05491@2157|Archaea,41SVB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6961371_0	436308.Nmar_0980	1.733e-226	705.0	COG0012@1|root,arCOG00357@2157|Archaea,41S8X@651137|Thaumarchaeota	651137|Thaumarchaeota	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
CMS3_k127_6961371_4	266779.Meso_0048	3.29e-17	92.0	COG1361@1|root,COG1361@2|Bacteria,1R5G4@1224|Proteobacteria,2UC86@28211|Alphaproteobacteria,43MTR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS3_k127_6982223_12	436308.Nmar_1704	5.511e-10	60.0	arCOG08775@1|root,arCOG08775@2157|Archaea,41T9K@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6982223_3	436308.Nmar_1705	3.291e-128	411.0	COG0528@1|root,arCOG00858@2157|Archaea,41T1R@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS3_k127_6982223_1	436308.Nmar_1706	3.54e-225	702.0	COG1078@1|root,arCOG04430@2157|Archaea,41T0P@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
CMS3_k127_6982223_4	436308.Nmar_1707	8.543e-93	308.0	COG0125@1|root,arCOG01891@2157|Archaea,41T33@651137|Thaumarchaeota	651137|Thaumarchaeota	F	thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS3_k127_6982223_8	436308.Nmar_1708	2.858e-44	164.0	COG0071@1|root,arCOG01832@2157|Archaea,41T74@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS3_k127_6982223_0	436308.Nmar_1709	2.106e-246	769.0	COG0661@1|root,arCOG01189@2157|Archaea,41SYQ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
CMS3_k127_6982223_7	1229909.NSED_09100	7.894e-55	194.0	arCOG03681@1|root,arCOG03681@2157|Archaea,41T6V@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6982223_14	585543.HMPREF0969_00227	5.51e-05	49.0	2FB5H@1|root,343BU@2|Bacteria,4P5M8@976|Bacteroidetes,2FYMR@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6982223_10	1229909.NSED_00260	4.102e-25	106.0	arCOG08724@1|root,arCOG08724@2157|Archaea,41TA8@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6982223_5	436308.Nmar_0111	1.455e-72	246.0	COG0432@1|root,arCOG04214@2157|Archaea,41T31@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS3_k127_6982223_6	436308.Nmar_0110	3.602e-69	237.0	arCOG08723@1|root,arCOG08723@2157|Archaea,41SPX@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_6982223_2	436308.Nmar_0109	4.88e-175	554.0	COG1537@1|root,arCOG01741@2157|Archaea,41S6V@651137|Thaumarchaeota	651137|Thaumarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	-	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_3
CMS3_k127_6982223_9	436308.Nmar_0108	5.108e-43	160.0	COG1324@1|root,arCOG04231@2157|Archaea,41SR4@651137|Thaumarchaeota	651137|Thaumarchaeota	P	PFAM CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CMS3_k127_6982223_13	436308.Nmar_0107	2.313e-09	58.0	COG0750@1|root,arCOG04064@2157|Archaea,41SW5@651137|Thaumarchaeota	651137|Thaumarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
CMS3_k127_7018629_2	1229909.NSED_08410	5.6e-187	587.0	COG0731@1|root,arCOG04174@2157|Archaea,41SBS@651137|Thaumarchaeota	651137|Thaumarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
CMS3_k127_7018629_9	1459636.NTE_02756	3.583e-45	168.0	COG0127@1|root,arCOG04184@2157|Archaea,41SKW@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Belongs to the HAM1 NTPase family	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS3_k127_7018629_4	436308.Nmar_1531	5.049e-95	314.0	COG0533@1|root,arCOG01185@2157|Archaea,41SJJ@651137|Thaumarchaeota	651137|Thaumarchaeota	T	Mn2 -dependent serine threonine protein kinase	-	-	2.7.11.1	ko:K08851	-	-	-	-	ko00000,ko01000,ko01001,ko03016	-	-	-	Pkinase
CMS3_k127_7018629_7	436308.Nmar_1532	1.808e-50	181.0	arCOG10590@1|root,arCOG10590@2157|Archaea,41SSG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_7018629_3	1229909.NSED_08430	5.433e-185	581.0	COG0533@1|root,arCOG01183@2157|Archaea,41SDX@651137|Thaumarchaeota	651137|Thaumarchaeota	L	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37	kae1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS3_k127_7018629_1	1229909.NSED_08435	1.699e-213	668.0	COG0012@1|root,arCOG00357@2157|Archaea,41S71@651137|Thaumarchaeota	651137|Thaumarchaeota	J	GTPase of unknown function C-terminal	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
CMS3_k127_7018629_6	1229909.NSED_08440	1.748e-53	193.0	COG1936@1|root,arCOG01038@2157|Archaea,41SPH@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
CMS3_k127_7018629_0	436308.Nmar_1536	6.324e-271	839.0	COG0343@1|root,arCOG00989@2157|Archaea,41SF4@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	-	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TGT
CMS3_k127_7018629_5	436308.Nmar_1537	6.422e-64	218.0	COG1145@1|root,arCOG00291@2157|Archaea,41SNB@651137|Thaumarchaeota	651137|Thaumarchaeota	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS3_k127_7024014_4	436308.Nmar_0386	7.961e-13	68.0	COG0250@1|root,arCOG01920@2157|Archaea,41SM6@651137|Thaumarchaeota	651137|Thaumarchaeota	K	Transcription elongation factor Spt5	spt5	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
CMS3_k127_7024014_3	1229909.NSED_01865	3.85e-28	113.0	COG2443@1|root,arCOG02204@2157|Archaea,41TA4@651137|Thaumarchaeota	651137|Thaumarchaeota	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	-	-	-	ko:K07342	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.7,3.A.5.8,3.A.5.9	-	-	-
CMS3_k127_7024014_0	436308.Nmar_0387	2.255e-126	408.0	COG1650@1|root,arCOG01616@2157|Archaea,41SM3@651137|Thaumarchaeota	651137|Thaumarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
CMS3_k127_7024014_1	436308.Nmar_0388	2.381e-48	174.0	COG0350@1|root,arCOG02724@2157|Archaea,41SR8@651137|Thaumarchaeota	651137|Thaumarchaeota	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CMS3_k127_7024014_2	436308.Nmar_0390	5.786e-44	161.0	COG2147@1|root,arCOG04089@2157|Archaea,41SVC@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl19e	-	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
CMS3_k127_7029266_2	436308.Nmar_0705	3.33e-50	188.0	COG1378@1|root,arCOG02037@2157|Archaea,41T5N@651137|Thaumarchaeota	651137|Thaumarchaeota	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
CMS3_k127_7029266_1	1229909.NSED_04815	1.485e-53	191.0	COG0745@1|root,arCOG02595@2157|Archaea,41T9R@651137|Thaumarchaeota	651137|Thaumarchaeota	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS3_k127_7029266_0	1229909.NSED_04820	7.067e-162	516.0	COG0642@1|root,arCOG02362@1|root,arCOG02358@2157|Archaea,arCOG02362@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE4,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1,sCache_3_3
CMS3_k127_70676_2	436308.Nmar_0595	4.511e-104	342.0	COG1215@1|root,arCOG01389@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011,ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
CMS3_k127_70676_1	436308.Nmar_0594	5.091e-190	598.0	COG0265@1|root,arCOG02833@2157|Archaea,41S9W@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Trypsin-like serine protease with C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS3_k127_70676_0	436308.Nmar_0593	6.95e-195	612.0	COG1060@1|root,arCOG00657@2157|Archaea,41S95@651137|Thaumarchaeota	651137|Thaumarchaeota	H	Radical SAM	-	-	2.5.1.77	ko:K11780	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS3_k127_7529299_3	436308.Nmar_0226	1.682e-31	123.0	COG2053@1|root,arCOG04314@2157|Archaea,41ST6@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	-	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
CMS3_k127_7529299_2	436308.Nmar_0227	1.041e-34	132.0	COG2075@1|root,arCOG01950@2157|Archaea,41T7M@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Binds to the 23S rRNA	rpl24e	-	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
CMS3_k127_7529299_1	1229909.NSED_00965	7.776e-72	243.0	COG0105@1|root,arCOG04313@2157|Archaea,41SN1@651137|Thaumarchaeota	651137|Thaumarchaeota	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS3_k127_7529299_0	436308.Nmar_0229	0.0	1043.0	COG0532@1|root,arCOG01560@2157|Archaea,41SBY@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D4,IF-2
CMS3_k127_9016_5	436308.Nmar_0722	5.816e-28	114.0	arCOG11724@1|root,arCOG11724@2157|Archaea	2157|Archaea	S	Arsenate reductase and related	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS3_k127_9016_2	1229909.NSED_03725	3.828e-41	152.0	arCOG10537@1|root,arCOG10537@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_9016_8	1144275.COCOR_05212	1.243e-05	57.0	COG3210@1|root,COG3210@2|Bacteria,1P4K4@1224|Proteobacteria	1224|Proteobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_9016_1	436308.Nmar_0719	2.241e-190	598.0	COG0601@1|root,arCOG00751@2157|Archaea,41S7B@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_9016_0	1229909.NSED_03705	2.11e-236	736.0	COG1173@1|root,arCOG00749@2157|Archaea,41SFE@651137|Thaumarchaeota	651137|Thaumarchaeota	P	inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS3_k127_9016_6	1131266.ARWQ01000002_gene623	1.385e-25	109.0	arCOG08751@1|root,arCOG08751@2157|Archaea,41SS7@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_9016_4	1131266.ARWQ01000002_gene624	2.581e-35	137.0	arCOG08750@1|root,arCOG08750@2157|Archaea,41SSB@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS3_k127_9016_7	1229909.NSED_06840	1.689e-15	75.0	COG4263@1|root,arCOG06217@2157|Archaea	2157|Archaea	C	Cytochrome C oxidase, subunit II	nosZ	-	1.7.2.4,1.9.3.1	ko:K00376,ko:K02275	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00529	R00081,R02804	RC00016,RC02861	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1,TAT_signal
## 1128 queries scanned
## Total time (seconds): 6.181173801422119
## Rate: 182.49 q/s