## Mon Nov 11 11:41:29 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS3_bin.9.fa -m mmseqs --itype genome -o CMS3_bin.9 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS3_bin.9 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs CMS3_k127_100422_1 1408433.JHXV01000036_gene251 1.206e-167 536.0 COG0579@1|root,COG0579@2|Bacteria,4NE0B@976|Bacteroidetes,1HZQJ@117743|Flavobacteriia,2PACG@246874|Cryomorphaceae 976|Bacteroidetes S FAD dependent oxidoreductase lhgO - - ko:K15736 - - - - ko00000,ko01000 - - - DAO CMS3_k127_100422_0 1434325.AZQN01000010_gene3965 2.134e-286 910.0 COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes 976|Bacteroidetes M Tricorn protease homolog - - - - - - - - - - - - Amidohydro_1,PD40 CMS3_k127_100422_3 1150600.ADIARSV_1790 9.675e-96 323.0 COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,1IQE6@117747|Sphingobacteriia 976|Bacteroidetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N CMS3_k127_100422_2 926549.KI421517_gene1504 2.608e-125 421.0 COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47JI8@768503|Cytophagia 976|Bacteroidetes S protease with the C-terminal PDZ domain - - - - - - - - - - - - Peptidase_M61 CMS3_k127_101993_0 1121904.ARBP01000017_gene5158 1.438e-137 443.0 COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47MQK@768503|Cytophagia 976|Bacteroidetes P Arylsulfatase A - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_101993_1 1408473.JHXO01000016_gene1928 2.438e-35 141.0 COG1595@1|root,COG1595@2|Bacteria,4NVR6@976|Bacteroidetes 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2 CMS3_k127_101993_3 1237149.C900_03216 2.071e-13 79.0 COG0457@1|root,COG0457@2|Bacteria,4PPNU@976|Bacteroidetes,47YQH@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_101993_2 545695.TREAZ_1687 9.347e-24 116.0 COG0653@1|root,COG0653@2|Bacteria 2|Bacteria U protein targeting secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW CMS3_k127_1035572_2 1122176.KB903552_gene3683 5.326e-57 203.0 COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,1IQYZ@117747|Sphingobacteriia 976|Bacteroidetes M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - - - - - - - - - - LGT CMS3_k127_1035572_1 760192.Halhy_6235 5.125e-128 415.0 COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes 976|Bacteroidetes S COGs COG3752 membrane protein - - - - - - - - - - - - DUF1295 CMS3_k127_1035572_0 761193.Runsl_2487 0.0 1339.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia 976|Bacteroidetes G Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_106043_2 1279009.ADICEAN_01017 1.487e-38 148.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47M5A@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_106043_3 929562.Emtol_1040 7.645e-13 75.0 COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 CMS3_k127_106043_1 313606.M23134_02442 2.278e-117 406.0 COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 CMS3_k127_106043_0 313603.FB2170_01821 4.028e-160 516.0 COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1HYG1@117743|Flavobacteriia,2PHV9@252356|Maribacter 976|Bacteroidetes E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS3_k127_106105_0 867902.Ornrh_0487 4.136e-115 381.0 COG0763@1|root,COG0763@2|Bacteria,4NDW3@976|Bacteroidetes,1HWRS@117743|Flavobacteriia 976|Bacteroidetes M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB CMS3_k127_106105_2 1279009.ADICEAN_00311 5.094e-64 232.0 COG0665@1|root,COG0665@2|Bacteria,4NFCD@976|Bacteroidetes,47JI9@768503|Cytophagia 976|Bacteroidetes E PFAM FAD dependent oxidoreductase thiO - - - - - - - - - - - DAO CMS3_k127_106105_1 1123276.KB893312_gene3098 3.24e-79 299.0 COG4775@1|root,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,47KAC@768503|Cytophagia 976|Bacteroidetes MU PFAM WD40-like beta Propeller - - - - - - - - - - - - PD40 CMS3_k127_106105_5 1172190.M947_08550 1.422e-05 57.0 COG0438@1|root,COG0438@2|Bacteria,1MWYH@1224|Proteobacteria,42Q22@68525|delta/epsilon subdivisions 1224|Proteobacteria M PFAM Glycosyl transferase, group 1 wcaC GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - ko:K13684 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_106105_3 1121875.KB907550_gene919 1.184e-50 183.0 COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H CMS3_k127_106105_4 761193.Runsl_1770 9.271e-29 129.0 COG0457@1|root,COG1201@1|root,COG0457@2|Bacteria,COG1201@2|Bacteria,4NE2V@976|Bacteroidetes,47Y0I@768503|Cytophagia 976|Bacteroidetes L Tetratricopeptide domain protein - - - - - - - - - - - - TPR_16,TPR_19,TPR_6,TPR_8 CMS3_k127_1081917_1 926549.KI421517_gene1641 6.033e-125 404.0 COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,47NTC@768503|Cytophagia 976|Bacteroidetes IQ KR domain - - 1.1.1.69 ko:K00046 - - - - ko00000,ko01000 - - - adh_short_C2 CMS3_k127_1081917_0 1122176.KB903536_gene1763 1.456e-222 712.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IUW9@117747|Sphingobacteriia 976|Bacteroidetes H Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 CMS3_k127_1081917_2 314230.DSM3645_19838 8.443e-50 184.0 COG3828@1|root,COG3828@2|Bacteria,2IZ1Z@203682|Planctomycetes 203682|Planctomycetes S Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_1083861_4 1150600.ADIARSV_2439 6.855e-50 181.0 COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Uncharacterised BCR, COG1649 - - - - - - - - - - - - GHL10 CMS3_k127_1083861_1 1313301.AUGC01000020_gene695 7.286e-100 332.0 COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes 976|Bacteroidetes G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS CMS3_k127_1083861_0 1237149.C900_00549 2.128e-304 943.0 COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,47KPX@768503|Cytophagia 976|Bacteroidetes G Glucosamine-6-phosphate isomerase nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso,PIG-L CMS3_k127_1083861_2 1121904.ARBP01000002_gene6688 1.147e-84 287.0 COG1349@1|root,COG1349@2|Bacteria,4NI1F@976|Bacteroidetes,47MTV@768503|Cytophagia 976|Bacteroidetes K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR CMS3_k127_1083861_3 1250278.JQNQ01000001_gene1898 1.019e-56 209.0 COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1I0N1@117743|Flavobacteriia 976|Bacteroidetes GV Glycosyl hydrolase family 3 N terminal domain - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_1090278_4 761193.Runsl_2439 3.534e-129 422.0 COG1073@1|root,COG1073@2|Bacteria,4NI6C@976|Bacteroidetes,47N3Z@768503|Cytophagia 976|Bacteroidetes S Acetyl xylan esterase - - - - - - - - - - - - AXE1 CMS3_k127_1090278_3 1122176.KB903532_gene2717 2.844e-134 437.0 COG0696@1|root,COG0696@2|Bacteria,4PNG1@976|Bacteroidetes,1J0YG@117747|Sphingobacteriia 976|Bacteroidetes G Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Metalloenzyme,Phosphodiest CMS3_k127_1090278_1 1121904.ARBP01000015_gene179 3.155e-182 601.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1090278_8 1237149.C900_00248 6.421e-41 154.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_1090278_6 243090.RB88 6.741e-63 240.0 COG3540@1|root,COG3540@2|Bacteria,2J1YU@203682|Planctomycetes 203682|Planctomycetes P PhoD-like phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD CMS3_k127_1090278_9 1121939.L861_13660 2.307e-05 57.0 COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotran_2,Arylsulfotrans CMS3_k127_1090278_0 344747.PM8797T_27352 4.669e-212 670.0 COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes 2|Bacteria P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase CMS3_k127_1090278_2 1123248.KB893318_gene4164 8.563e-174 557.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_1090278_5 1250278.JQNQ01000001_gene1742 1.575e-90 303.0 COG2067@1|root,COG2067@2|Bacteria,4NGWZ@976|Bacteroidetes,1IJ7F@117743|Flavobacteriia 976|Bacteroidetes I Protein of unknown function (DUF2490) - - - - - - - - - - - - DUF2490 CMS3_k127_1090278_7 1094466.KQS_06590 6.195e-62 227.0 COG2304@1|root,COG3291@1|root,COG2304@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IJ8A@117743|Flavobacteriia,2P0KQ@237|Flavobacterium 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - CHU_C,Gal_Lectin,HYR,Laminin_G_3,PKD,SprB,TSP_3 CMS3_k127_1091011_0 489825.LYNGBM3L_33080 1.669e-125 411.0 COG3497@1|root,COG3497@2|Bacteria,1G41S@1117|Cyanobacteria,1HEID@1150|Oscillatoriales 1117|Cyanobacteria S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C CMS3_k127_1091011_4 1237149.C900_01817 3.82e-05 55.0 2DSUR@1|root,33HH4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1091011_3 1443665.JACA01000001_gene2568 3.051e-44 167.0 2C0BR@1|root,32Z3H@2|Bacteria,4NVDW@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF4255) - - - - - - - - - - - - DUF4255 CMS3_k127_1091011_2 997884.HMPREF1068_02550 1.416e-48 186.0 COG2755@1|root,COG2755@2|Bacteria,4NSWA@976|Bacteroidetes,2FUHI@200643|Bacteroidia,4AU2E@815|Bacteroidaceae 976|Bacteroidetes E lipolytic protein G-D-S-L family - - - - - - - - - - - - - CMS3_k127_1091011_1 997884.HMPREF1068_02549 7.322e-91 307.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,2FM3F@200643|Bacteroidia,4AK8P@815|Bacteroidaceae 976|Bacteroidetes M Psort location CytoplasmicMembrane, score 10.00 algI - - - - - - - - - - - MBOAT CMS3_k127_1095001_4 1492737.FEM08_25310 5.516e-57 216.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,1HX9X@117743|Flavobacteriia,2NSX4@237|Flavobacterium 976|Bacteroidetes N Gliding motility protein GldG gldG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux CMS3_k127_1095001_1 1189612.A33Q_3068 7.038e-213 672.0 COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia 976|Bacteroidetes I PFAM Carbamoyl-phosphate synthase L chain, ATP binding - - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K01961,ko:K01965 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00373,M00376,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CMS3_k127_1095001_3 313606.M23134_01723 3.397e-70 246.0 COG2454@1|root,COG2454@2|Bacteria,4NN3Y@976|Bacteroidetes,47RKQ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF434) - - - - - - - - - - - - DUF434 CMS3_k127_1095001_5 926559.JoomaDRAFT_3126 3.706e-20 96.0 28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1095001_2 1237149.C900_00811 1.742e-188 597.0 COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,47JBT@768503|Cytophagia 976|Bacteroidetes E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CMS3_k127_1095001_0 1121904.ARBP01000006_gene4025 2.394e-268 833.0 COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_10977_6 926562.Oweho_2251 3.337e-40 153.0 COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,1I2P9@117743|Flavobacteriia,2PB1D@246874|Cryomorphaceae 976|Bacteroidetes Q Thioesterase superfamily paaI - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT CMS3_k127_10977_5 616991.JPOO01000001_gene3965 3.781e-113 371.0 COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,1IIGJ@117743|Flavobacteriia 976|Bacteroidetes IQ KR domain - - 1.3.1.25 ko:K05783 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113 RC00271,RC01326,RC01327 br01602,ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 CMS3_k127_10977_2 313606.M23134_02060 7.851e-203 637.0 COG1960@1|root,COG1960@2|Bacteria,4NH3I@976|Bacteroidetes,47MEG@768503|Cytophagia 976|Bacteroidetes I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_10977_4 1288963.ADIS_4099 5.482e-129 424.0 2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes,47UJY@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - VCBS CMS3_k127_10977_3 1122176.KB903543_gene469 7.556e-160 541.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HTH_18,HisKA,Response_reg,TPR_12,TPR_8 CMS3_k127_10977_0 616991.JPOO01000003_gene1601 2.767e-255 793.0 COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,1HZRB@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_10977_1 471854.Dfer_2203 4.111e-231 728.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47MX6@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - Laminin_G_3,PSCyt1,PSCyt2,PSD1 CMS3_k127_1103420_4 1122179.KB890416_gene2620 2.293e-91 304.0 COG0288@1|root,COG0288@2|Bacteria,4NH0X@976|Bacteroidetes 976|Bacteroidetes P Reversible hydration of carbon dioxide - - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA CMS3_k127_1103420_1 865937.Gilli_1171 6.126e-122 397.0 COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1HXVW@117743|Flavobacteriia 976|Bacteroidetes H Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 CMS3_k127_1103420_2 1121875.KB907550_gene698 1.564e-111 369.0 COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,1HYWC@117743|Flavobacteriia 976|Bacteroidetes U WD40-like Beta Propeller - - - - - - - - - - - - PD40 CMS3_k127_1103420_5 1123261.AXDW01000001_gene1058 1.44e-77 271.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X462@135614|Xanthomonadales 135614|Xanthomonadales M Male sterility protein - - - - - - - - - - - - Epimerase CMS3_k127_1103420_3 1122176.KB903551_gene4221 1.501e-92 319.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1ISYB@117747|Sphingobacteriia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_1103420_7 926549.KI421517_gene2472 6.345e-48 177.0 COG0454@1|root,COG0456@2|Bacteria,4NNJS@976|Bacteroidetes,47PUS@768503|Cytophagia 976|Bacteroidetes K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_1103420_0 700598.Niako_1203 8.712e-156 521.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1103420_10 163908.KB235896_gene4774 7.631e-29 118.0 COG1324@1|root,COG1324@2|Bacteria,1G7PJ@1117|Cyanobacteria,1HP9B@1161|Nostocales 1117|Cyanobacteria P PFAM CutA1 divalent ion tolerance protein cutA - - ko:K03926 - - - - ko00000 - - - CutA1 CMS3_k127_1103420_6 1538644.KO02_11840 7.167e-75 257.0 COG0259@1|root,COG0259@2|Bacteria,4NFH7@976|Bacteroidetes,1IRWF@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx CMS3_k127_1103420_8 192952.MM_1124 5.251e-47 186.0 COG2244@1|root,arCOG02211@2157|Archaea,2Y2H0@28890|Euryarchaeota 28890|Euryarchaeota S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt_3 CMS3_k127_1103420_9 385682.AFSL01000065_gene1659 1.158e-32 132.0 COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,2FYDH@200643|Bacteroidia,3XK6A@558415|Marinilabiliaceae 976|Bacteroidetes F NUDIX domain - - - - - - - - - - - - NUDIX CMS3_k127_1107552_0 929703.KE386491_gene3144 5.834e-89 298.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia 976|Bacteroidetes K PFAM MerR family regulatory protein - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 CMS3_k127_1107552_1 1392490.JHZX01000001_gene362 3.925e-60 213.0 COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,1HYNJ@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the peptidase M16 family pqqL - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_1110175_1 468059.AUHA01000002_gene427 2.118e-242 757.0 COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,1IPZE@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the heme-copper respiratory oxidase family ctaD - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 CMS3_k127_1110175_4 1123248.KB893319_gene3965 5.04e-78 273.0 COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,1IPEE@117747|Sphingobacteriia 976|Bacteroidetes C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM CMS3_k127_1110175_3 761193.Runsl_2967 7.056e-91 315.0 COG4531@1|root,COG4531@2|Bacteria,4NF0R@976|Bacteroidetes,47JUF@768503|Cytophagia 976|Bacteroidetes P Quinol cytochrome c oxidoreductase actF - - - - - - - - - - - - CMS3_k127_1110175_7 1042376.AFPK01000072_gene1750 5.625e-32 133.0 COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,1HYBP@117743|Flavobacteriia,406HU@61432|unclassified Flavobacteriaceae 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III actE - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_1110175_6 1122621.ATZA01000026_gene2223 5.054e-42 160.0 COG2010@1|root,COG2010@2|Bacteria,4NEX9@976|Bacteroidetes,1ITKW@117747|Sphingobacteriia 976|Bacteroidetes C Quinol cytochrome c oxidoreductase actD - - - - - - - - - - - DUF3341 CMS3_k127_1110175_2 926549.KI421517_gene1907 5.598e-204 644.0 COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia 976|Bacteroidetes C PFAM Polysulphide reductase, NrfD nrfD - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD CMS3_k127_1110175_0 1237149.C900_03264 5.294e-286 911.0 COG0437@1|root,COG0437@2|Bacteria,4NE5M@976|Bacteroidetes,47NK7@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain nrfC - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7,Molydop_binding CMS3_k127_1110175_5 926562.Oweho_1930 1.72e-70 248.0 COG3474@1|root,COG3474@2|Bacteria,4PKQA@976|Bacteroidetes,1I8RP@117743|Flavobacteriia,2PAPE@246874|Cryomorphaceae 976|Bacteroidetes C PFAM Class III cytochrome C family - - - - - - - - - - - - Cytochrom_C,Cytochrom_CIII,Cytochrome_C7 CMS3_k127_111054_0 388413.ALPR1_05160 5.464e-157 515.0 COG1132@1|root,COG1132@2|Bacteria,4NE2D@976|Bacteroidetes,47JQI@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region msbA - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CMS3_k127_111054_3 742767.HMPREF9456_00618 1.548e-17 86.0 COG0858@1|root,COG0858@2|Bacteria,4NSQJ@976|Bacteroidetes,2FT27@200643|Bacteroidia,22YGP@171551|Porphyromonadaceae 976|Bacteroidetes J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA CMS3_k127_111054_1 742727.HMPREF9447_02762 4.281e-78 276.0 COG4591@1|root,COG4591@2|Bacteria,4NG04@976|Bacteroidetes,2FNHB@200643|Bacteroidia,4AKWK@815|Bacteroidaceae 976|Bacteroidetes M COG4591 ABC-type transport system, involved in lipoprotein release, permease component lolE - - ko:K09808,ko:K09815 ko02010,map02010 M00242,M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125,3.A.1.15.3,3.A.1.15.5 - - FtsX,MacB_PCD CMS3_k127_111054_2 1121373.KB903627_gene2952 3.295e-53 208.0 COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,47KRB@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag CMS3_k127_1112841_0 143224.JQMD01000002_gene3407 7.581e-127 420.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1HXT6@117743|Flavobacteriia 976|Bacteroidetes M sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 CMS3_k127_1114934_7 391625.PPSIR1_25316 5.012e-36 137.0 COG3497@1|root,COG3497@2|Bacteria,1MX89@1224|Proteobacteria,42NJI@68525|delta/epsilon subdivisions,2WJI8@28221|Deltaproteobacteria,2YYYZ@29|Myxococcales 28221|Deltaproteobacteria S Phage tail sheath C-terminal domain - - - ko:K06907 - - - - ko00000 - - - Phage_sheath_1,Phage_sheath_1C CMS3_k127_1114934_1 391625.PPSIR1_25311 1.915e-58 206.0 2B9U6@1|root,32372@2|Bacteria,1RHAQ@1224|Proteobacteria,43DJF@68525|delta/epsilon subdivisions,2X8QQ@28221|Deltaproteobacteria,2Z2FA@29|Myxococcales 28221|Deltaproteobacteria S T4-like virus tail tube protein gp19 - - - - - - - - - - - - Phage_T4_gp19 CMS3_k127_1114934_6 1443665.JACA01000001_gene2564 5.347e-37 144.0 2FCGJ@1|root,344K0@2|Bacteria,4P5PM@976|Bacteroidetes 976|Bacteroidetes S T4-like virus tail tube protein gp19 - - - - - - - - - - - - Phage_T4_gp19 CMS3_k127_1114934_2 1254432.SCE1572_26880 7.623e-56 199.0 2DMQT@1|root,32T2H@2|Bacteria,1N211@1224|Proteobacteria,42U4F@68525|delta/epsilon subdivisions,2WQNK@28221|Deltaproteobacteria,2Z2AW@29|Myxococcales 28221|Deltaproteobacteria S T4-like virus tail tube protein gp19 - - - - - - - - - - - - Phage_T4_gp19 CMS3_k127_1114934_3 1254432.SCE1572_26870 2.271e-54 199.0 COG1652@1|root,COG1652@2|Bacteria,1RF5U@1224|Proteobacteria,42U0Q@68525|delta/epsilon subdivisions,2WQG5@28221|Deltaproteobacteria,2Z0XH@29|Myxococcales 28221|Deltaproteobacteria S LysM domain - - - - - - - - - - - - - CMS3_k127_1114934_0 489825.LYNGBM3L_33140 2.939e-153 501.0 COG3501@1|root,COG3501@2|Bacteria,1G3M3@1117|Cyanobacteria,1H9TY@1150|Oscillatoriales 1117|Cyanobacteria S Phage late control gene D protein (GPD) - - - - - - - - - - - - Phage_GPD CMS3_k127_1114934_5 391625.PPSIR1_25276 3.35e-39 150.0 COG3628@1|root,COG3628@2|Bacteria,1N23A@1224|Proteobacteria,42UNM@68525|delta/epsilon subdivisions,2WQD8@28221|Deltaproteobacteria,2Z23J@29|Myxococcales 28221|Deltaproteobacteria S Gene 25-like lysozyme - - - ko:K06903 - - - - ko00000 - - - GPW_gp25 CMS3_k127_1114934_4 1173028.ANKO01000114_gene6157 6.619e-53 193.0 2CBUW@1|root,32RU3@2|Bacteria,1GD9V@1117|Cyanobacteria,1HFJ1@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_1114934_8 489825.LYNGBM3L_49000 3.431e-23 104.0 COG3299@1|root,COG3299@2|Bacteria 2|Bacteria S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J CMS3_k127_1117032_2 1123248.KB893314_gene3576 2.334e-16 80.0 COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1ISVX@117747|Sphingobacteriia 976|Bacteroidetes T Protein of unknown function (DUF3467) - - - - - - - - - - - - DUF3467 CMS3_k127_1117032_0 929556.Solca_2584 5.816e-225 722.0 COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1IQGH@117747|Sphingobacteriia 976|Bacteroidetes L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII CMS3_k127_1117032_1 56110.Oscil6304_2815 6.149e-53 205.0 COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales 1117|Cyanobacteria O Beta-propeller repeat - - - - - - - - - - - - Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP CMS3_k127_1117125_7 714943.Mucpa_4413 6.736e-11 65.0 COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,1IS07@117747|Sphingobacteriia 976|Bacteroidetes S Anti-sigma-K factor rskA - - - - - - - - - - - - RskA CMS3_k127_1117125_6 468059.AUHA01000002_gene272 3.694e-45 169.0 COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes,1IS9P@117747|Sphingobacteriia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_1117125_0 1121904.ARBP01000007_gene3139 0.0 1047.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,47MNR@768503|Cytophagia 976|Bacteroidetes G Transketolase, thiamine diphosphate binding domain tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N CMS3_k127_1117125_1 1408473.JHXO01000006_gene1118 5.463e-216 679.0 COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,2FPIS@200643|Bacteroidia 976|Bacteroidetes G Carbohydrate kinase, FGGY family protein xylB_2 - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N CMS3_k127_1117125_5 929562.Emtol_3457 4.157e-99 333.0 COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,47KU9@768503|Cytophagia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - 1.8.3.7 ko:K13444 ko04142,map04142 - - - ko00000,ko00001,ko01000 - - - FGE-sulfatase CMS3_k127_1117125_2 1121904.ARBP01000026_gene668 2.026e-196 627.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,47KCU@768503|Cytophagia 976|Bacteroidetes H Domain of unknown function (DUF4301) - - - - - - - - - - - - DUF4301 CMS3_k127_1117125_3 1122179.KB890441_gene1069 2.97e-177 581.0 COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia 976|Bacteroidetes U PFAM PKD domain - - - - - - - - - - - - CHU_C,IgGFc_binding,PKD,SprB CMS3_k127_1117125_4 1122179.KB890441_gene1069 1.016e-116 394.0 COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia 976|Bacteroidetes U PFAM PKD domain - - - - - - - - - - - - CHU_C,IgGFc_binding,PKD,SprB CMS3_k127_1125115_0 929562.Emtol_0861 3.242e-179 571.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47K4A@768503|Cytophagia 976|Bacteroidetes C PFAM Aldehyde dehydrogenase - - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_1125115_3 1237149.C900_03509 1.726e-14 75.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,47RU4@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bS21 family rpsU - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 CMS3_k127_1125115_1 1349822.NSB1T_05760 1.595e-79 276.0 COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,2FNFK@200643|Bacteroidia,22WRA@171551|Porphyromonadaceae 976|Bacteroidetes L Belongs to the 'phage' integrase family xerC - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase CMS3_k127_1125115_2 485917.Phep_0841 4.659e-25 106.0 COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,1IXVN@117747|Sphingobacteriia 976|Bacteroidetes J Sigma 54 modulation protein / S30EA ribosomal protein raiA - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosomal_S30AE CMS3_k127_1125381_1 1408433.JHXV01000005_gene2349 2.976e-30 133.0 COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia,2PBIN@246874|Cryomorphaceae 976|Bacteroidetes S LVIVD repeat - - - - - - - - - - - - CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3 CMS3_k127_1125381_0 1168034.FH5T_05330 6.875e-62 228.0 COG0739@1|root,COG0739@2|Bacteria,4NECF@976|Bacteroidetes,2FQ2Q@200643|Bacteroidia 976|Bacteroidetes M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 CMS3_k127_1126586_0 743722.Sph21_0856 3.946e-156 510.0 COG4565@1|root,COG4584@1|root,COG4565@2|Bacteria,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,1IPYU@117747|Sphingobacteriia 976|Bacteroidetes L PFAM Integrase, catalytic core - - - - - - - - - - - - HTH_11,HTH_7,rve CMS3_k127_1126586_1 1121904.ARBP01000095_gene1598 1.996e-97 323.0 COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,47P7E@768503|Cytophagia 976|Bacteroidetes L PFAM IstB domain protein ATP-binding protein - - - - - - - - - - - - IstB_IS21 CMS3_k127_1126586_2 388413.ALPR1_18013 2.035e-62 218.0 COG0863@1|root,COG0863@2|Bacteria,4NTFS@976|Bacteroidetes,47WI4@768503|Cytophagia 976|Bacteroidetes L DNA methylase - - - - - - - - - - - - N6_N4_Mtase CMS3_k127_1128252_1 1185876.BN8_06598 1.684e-13 73.0 COG2017@1|root,COG2017@2|Bacteria,4NHUW@976|Bacteroidetes,47KZF@768503|Cytophagia 976|Bacteroidetes G converts alpha-aldose to the beta-anomer - - - - - - - - - - - - - CMS3_k127_1128252_0 1380600.AUYN01000009_gene1868 0.0 1392.0 COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4PNA4@976|Bacteroidetes,1IK7X@117743|Flavobacteriia 976|Bacteroidetes CG Trehalose utilisation - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,GSDH,PKD,ThuA CMS3_k127_1128252_2 1123242.JH636435_gene1636 5.491e-09 63.0 2EBZG@1|root,335YS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1130427_0 411154.GFO_2173 1.785e-223 699.0 COG0160@1|root,COG0160@2|Bacteria,4NFWF@976|Bacteroidetes,1HY4F@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19,2.6.1.22 ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_1130427_1 746697.Aeqsu_2891 2.313e-163 517.0 COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1HY7N@117743|Flavobacteriia 976|Bacteroidetes S Pfam Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase CMS3_k127_1130427_2 1120951.AUBG01000003_gene2784 6.431e-47 174.0 COG1982@1|root,COG1982@2|Bacteria,4NHSM@976|Bacteroidetes,1I0X3@117743|Flavobacteriia 976|Bacteroidetes E PFAM Orn Lys Arg decarboxylase, C-terminal domain - - 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C CMS3_k127_1131927_2 1239962.C943_00084 7.055e-46 167.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,4NF4F@976|Bacteroidetes 976|Bacteroidetes C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C CMS3_k127_1131927_3 1185876.BN8_01419 7.303e-31 124.0 COG1695@1|root,COG1695@2|Bacteria,4P48E@976|Bacteroidetes,47V9J@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_1131927_1 388413.ALPR1_13974 1.137e-104 374.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_1131927_0 1267211.KI669560_gene1467 1.874e-175 565.0 COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase M61 - - - - - - - - - - - - PDZ_2,Peptidase_M61 CMS3_k127_1145104_7 1485545.JQLW01000013_gene1854 2.196e-05 47.0 COG3744@1|root,COG3744@2|Bacteria,1NA89@1224|Proteobacteria 1224|Proteobacteria S PFAM PilT protein domain protein - - - - - - - - - - - - PIN CMS3_k127_1145104_6 869209.Tresu_0743 9.598e-06 50.0 2AMXV@1|root,31CUU@2|Bacteria,2J8VQ@203691|Spirochaetes 203691|Spirochaetes S IMG reference gene - - - - - - - - - - - - DUF2281 CMS3_k127_1145104_0 983544.Lacal_2774 1.493e-155 509.0 COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,4NHVF@976|Bacteroidetes,1HZ8C@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF3471,TPR_2 CMS3_k127_1145104_3 1122605.KB893625_gene1828 2.799e-84 281.0 COG2514@1|root,COG2514@2|Bacteria,4NMJC@976|Bacteroidetes,1ISH3@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase CMS3_k127_1145104_2 1227739.Hsw_0416 8.104e-94 314.0 COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,47KW6@768503|Cytophagia 976|Bacteroidetes G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM CMS3_k127_1145104_1 929562.Emtol_3604 5.642e-128 428.0 COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,47M5P@768503|Cytophagia 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - PA,Peptidase_M28 CMS3_k127_1145104_4 391625.PPSIR1_11110 6.872e-57 207.0 COG2988@1|root,COG2988@2|Bacteria 2|Bacteria E succinylglutamate desuccinylase activity astE - 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - - AstE_AspA CMS3_k127_1149790_1 1313301.AUGC01000018_gene768 4.606e-36 156.0 COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes 976|Bacteroidetes M PFAM WD domain, G-beta repeat - - - - - - - - - - - - WD40 CMS3_k127_1149790_0 32057.KB217480_gene8354 4.78e-123 421.0 COG0823@1|root,COG2319@1|root,COG4249@1|root,COG0823@2|Bacteria,COG2319@2|Bacteria,COG4249@2|Bacteria,1FZVW@1117|Cyanobacteria 1117|Cyanobacteria A WD domain, G-beta repeat - - - - - - - - - - - - Peptidase_C14,WD40 CMS3_k127_1149790_2 593907.Celgi_0153 3.018e-26 112.0 COG1832@1|root,COG1832@2|Bacteria,2IJYY@201174|Actinobacteria 201174|Actinobacteria S PFAM CoA-binding domain protein - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 CMS3_k127_1154074_1 760192.Halhy_5005 6.211e-169 538.0 COG0654@1|root,COG0654@2|Bacteria,4NHEE@976|Bacteroidetes,1IQ0F@117747|Sphingobacteriia 976|Bacteroidetes C COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent - - 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R01298 RC00046 ko00000,ko00001,ko01000 - - - FAD_binding_3 CMS3_k127_1154074_0 382464.ABSI01000007_gene4159 3.081e-170 545.0 COG3250@1|root,COG3250@2|Bacteria,46TJM@74201|Verrucomicrobia,2IVDN@203494|Verrucomicrobiae 203494|Verrucomicrobiae G alpha-L-rhamnosidase - - - - - - - - - - - - Glyco_hydro_106 CMS3_k127_1156141_1 313606.M23134_07796 1.465e-122 400.0 COG0552@1|root,COG0552@2|Bacteria,4NE9Z@976|Bacteroidetes,47JVI@768503|Cytophagia 976|Bacteroidetes U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N CMS3_k127_1156141_0 1279009.ADICEAN_03427 2.414e-176 564.0 COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 rimO - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 CMS3_k127_1156141_3 1519464.HY22_11300 7.041e-12 77.0 COG4219@1|root,COG4219@2|Bacteria,1FF12@1090|Chlorobi 1090|Chlorobi KT Peptidase M56 - - - - - - - - - - - - - CMS3_k127_1156141_2 1121104.AQXH01000001_gene1120 3.515e-55 208.0 COG4399@1|root,COG4399@2|Bacteria 2|Bacteria - - yheB - - - - - - - - - - - DUF445 CMS3_k127_1156141_4 1121007.AUML01000003_gene2574 2.252e-07 56.0 COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,1HXWQ@117743|Flavobacteriia,2YISZ@290174|Aquimarina 976|Bacteroidetes S Bacillithiol biosynthesis BshC bshC - - ko:K22136 - - - - ko00000 - - - BshC CMS3_k127_1164431_0 1121904.ARBP01000052_gene3645 9.57e-72 271.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47Y22@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_1183586_2 1122179.KB890423_gene2326 1.015e-112 370.0 COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,1INM9@117747|Sphingobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - Cupin_2,HTH_18 CMS3_k127_1183586_0 1121904.ARBP01000008_gene3299 1.104e-190 601.0 COG4948@1|root,COG4948@2|Bacteria,4NIIJ@976|Bacteroidetes,47XJS@768503|Cytophagia 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.6,5.5.1.27 ko:K01684,ko:K18983 ko00052,ko00053,ko01100,ko01120,map00052,map00053,map01100,map01120 M00552 R03033,R10847 RC00543,RC03287 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_1183586_1 313628.LNTAR_22714 2.583e-154 503.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_1183586_3 595460.RRSWK_03845 1.086e-20 95.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CMS3_k127_1197199_3 1288963.ADIS_0486 1.813e-113 377.0 COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,47MPU@768503|Cytophagia 976|Bacteroidetes G glycoside hydrolase family 2 sugar binding - - - - - - - - - - - - Glyco_hydro_106 CMS3_k127_1197199_2 153721.MYP_2294 2.665e-136 448.0 COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47MQK@768503|Cytophagia 976|Bacteroidetes P Arylsulfatase A - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_1197199_0 1288963.ADIS_0483 1.962e-206 652.0 COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47NG8@768503|Cytophagia 976|Bacteroidetes GP Domain of unknown function (DUF4976) - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_1197199_1 1288963.ADIS_0499 4.662e-158 508.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,47MNP@768503|Cytophagia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_1197430_0 517418.Ctha_0561 1.204e-38 151.0 COG4636@1|root,COG4636@2|Bacteria,1FFDX@1090|Chlorobi 1090|Chlorobi S Putative restriction endonuclease - - - - - - - - - - - - Uma2 CMS3_k127_1197430_1 112098.XP_008614098.1 3.081e-19 100.0 COG0666@1|root,KOG0502@2759|Eukaryota 2759|Eukaryota J nerve growth factor signaling pathway - - - - - - - - - - - - Ank,Ank_2,Ank_4 CMS3_k127_1197430_2 1408433.JHXV01000015_gene1764 7.925e-06 53.0 2CK3X@1|root,32SBI@2|Bacteria,4NSVD@976|Bacteroidetes,1I4GM@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1199240_2 1484460.JSWG01000015_gene1185 2.435e-34 134.0 COG1953@1|root,COG1953@2|Bacteria,4NFK3@976|Bacteroidetes 976|Bacteroidetes FH PFAM Permease for cytosine purines, uracil, thiamine, allantoin - - - ko:K03457 - - - - ko00000 2.A.39 - - Transp_cyt_pur CMS3_k127_1199240_1 1484460.JSWG01000015_gene1186 2.698e-202 640.0 COG0591@1|root,COG0591@2|Bacteria,4PKS6@976|Bacteroidetes,1IJEC@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF CMS3_k127_1199240_0 1123278.KB893488_gene6138 6.508e-241 750.0 COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia 976|Bacteroidetes F TIGRFAM dihydroorotase, multifunctional complex type - - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 CMS3_k127_1200646_9 1492738.FEM21_23220 7.917e-10 63.0 2CFVU@1|root,3373K@2|Bacteria,4NY6U@976|Bacteroidetes,1ID3F@117743|Flavobacteriia,2NX5E@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1200646_7 760192.Halhy_2922 8.553e-35 140.0 COG3385@1|root,COG3385@2|Bacteria,4P3S2@976|Bacteroidetes 976|Bacteroidetes L Pfam Transposase DDE domain - - - - - - - - - - - - DDE_5 CMS3_k127_1200646_8 880070.Cycma_4319 9.927e-32 125.0 COG0053@1|root,COG0053@2|Bacteria,4NVGY@976|Bacteroidetes,47SZY@768503|Cytophagia 976|Bacteroidetes P manually curated - - - - - - - - - - - - MerC CMS3_k127_1200646_2 1121875.KB907549_gene1946 5.937e-122 398.0 COG3842@1|root,COG3842@2|Bacteria,4NK56@976|Bacteroidetes,1I0DW@117743|Flavobacteriia 976|Bacteroidetes E ATPases associated with a variety of cellular activities - - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran CMS3_k127_1200646_4 1121875.KB907549_gene1945 6.04e-107 351.0 COG4149@1|root,COG4149@2|Bacteria,4NIXK@976|Bacteroidetes,1I0Y9@117743|Flavobacteriia 976|Bacteroidetes P Molybdate ABC transporter permease modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 CMS3_k127_1200646_6 1121875.KB907549_gene1943 3.701e-86 292.0 COG0725@1|root,COG0725@2|Bacteria,4NMPV@976|Bacteroidetes,1I1B0@117743|Flavobacteriia 976|Bacteroidetes P ABC transporter, periplasmic molybdate-binding protein modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 CMS3_k127_1200646_1 313603.FB2170_04860 2.612e-140 452.0 COG0226@1|root,COG0226@2|Bacteria,4NH1G@976|Bacteroidetes,1IIZQ@117743|Flavobacteriia 976|Bacteroidetes P PBP superfamily domain pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like,PBP_like_2 CMS3_k127_1200646_5 765869.BDW_05840 6.323e-98 327.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2MUPD@213481|Bdellovibrionales,2WJJ1@28221|Deltaproteobacteria 213481|Bdellovibrionales P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 CMS3_k127_1200646_0 313603.FB2170_04870 1.037e-141 454.0 COG0581@1|root,COG0581@2|Bacteria,4NGBA@976|Bacteroidetes,1I16J@117743|Flavobacteriia 976|Bacteroidetes P permease protein PstA pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CMS3_k127_1200646_3 313603.FB2170_04875 3.264e-121 393.0 COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1HZHC@117743|Flavobacteriia 976|Bacteroidetes P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran CMS3_k127_1208156_3 518766.Rmar_2185 3.912e-53 213.0 COG0265@1|root,COG2203@1|root,COG2972@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2972@2|Bacteria,4NHXJ@976|Bacteroidetes 976|Bacteroidetes T Signal transduction histidine kinase LytS - - - - - - - - - - - - His_kinase,Pentapeptide CMS3_k127_1208156_4 1121920.AUAU01000004_gene852 6.54e-43 168.0 COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria 57723|Acidobacteria T LytTr DNA-binding domain - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_1208156_1 929556.Solca_3282 5.771e-85 287.0 COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1IPC1@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase CMS3_k127_1208156_2 1279009.ADICEAN_01112 1.64e-63 227.0 COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,47K2K@768503|Cytophagia 976|Bacteroidetes G Inositol monophosphatase suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CMS3_k127_1208156_0 743722.Sph21_0674 0.0 1139.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1IPHM@117747|Sphingobacteriia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW CMS3_k127_1209383_0 929562.Emtol_4002 4.557e-128 417.0 COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia 976|Bacteroidetes E Peptidase family M1 domain - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4,Peptidase_M1 CMS3_k127_1209383_1 1519464.HY22_05255 8.068e-29 124.0 2ETC6@1|root,33KW3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1209383_2 1121948.AUAC01000003_gene2284 1.414e-16 79.0 COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,2UBN7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - PIN CMS3_k127_1215392_1 886379.AEWI01000013_gene2137 2.702e-160 512.0 COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,2FN0A@200643|Bacteroidia,3XIPH@558415|Marinilabiliaceae 976|Bacteroidetes J Class II release factor RF3, C-terminal domain prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,RF3_C CMS3_k127_1215392_9 7668.SPU_019149-tr 2.479e-26 119.0 COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria 33208|Metazoa M ankyrin 3, node of Ranvier (ankyrin G) - - - - - - - - - - - - Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5 CMS3_k127_1215392_7 1237149.C900_03775 3.832e-45 180.0 COG4192@1|root,COG4192@2|Bacteria,4NFY7@976|Bacteroidetes,47MMQ@768503|Cytophagia 976|Bacteroidetes T Domain of unknown function (DUF4407) - - - - - - - - - - - - DUF4407 CMS3_k127_1215392_10 1121403.AUCV01000073_gene1307 2.511e-26 124.0 COG1345@1|root,COG3209@1|root,COG3485@1|root,COG4676@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,COG3485@2|Bacteria,COG4676@2|Bacteria,1R0C4@1224|Proteobacteria,43CUG@68525|delta/epsilon subdivisions,2X825@28221|Deltaproteobacteria 28221|Deltaproteobacteria M TIGRFAM RHS repeat-associated core domain - - - - - - - - - - - - - CMS3_k127_1215392_8 1078020.KEK_12523 9.868e-32 138.0 COG1432@1|root,COG1432@2|Bacteria,2HB6H@201174|Actinobacteria,23514@1762|Mycobacteriaceae 201174|Actinobacteria S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH CMS3_k127_1215392_3 1237149.C900_00369 5.637e-120 397.0 COG1104@1|root,COG1104@2|Bacteria,4NFF6@976|Bacteroidetes,47MAZ@768503|Cytophagia 976|Bacteroidetes E PFAM aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CMS3_k127_1215392_2 1121904.ARBP01000005_gene4647 2.038e-121 398.0 COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,47J9J@768503|Cytophagia 976|Bacteroidetes C NAD(P)H quinone oxidoreductase, PIG3 family - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 CMS3_k127_1215392_0 216432.CA2559_08836 2.86e-181 579.0 COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,1HWVH@117743|Flavobacteriia 976|Bacteroidetes G Phosphoglucosamine mutase glmM - 5.4.2.8 ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01818 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS3_k127_1215392_6 1444711.CCJF01000005_gene1178 2.956e-59 218.0 COG2515@1|root,COG2515@2|Bacteria,2JG5N@204428|Chlamydiae 204428|Chlamydiae E 1-aminocyclopropane-1-carboxylate deaminase - - - - - - - - - - - - PALP CMS3_k127_1215392_5 929556.Solca_0293 2.877e-90 323.0 COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,1IRAV@117747|Sphingobacteriia 976|Bacteroidetes S oxidoreductase activity - - - - - - - - - - - - - CMS3_k127_1215392_4 531844.FIC_02572 3.864e-98 327.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia,405ZB@61432|unclassified Flavobacteriaceae 976|Bacteroidetes IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_1215392_11 525373.HMPREF0766_12230 3.386e-10 60.0 COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1IPZY@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase S46 dpp7 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Peptidase_S46 CMS3_k127_1226958_3 268407.PWYN_19905 1.681e-80 274.0 COG0702@1|root,COG0702@2|Bacteria,1VSVU@1239|Firmicutes,4HUSA@91061|Bacilli,26VKI@186822|Paenibacillaceae 91061|Bacilli GM epimerase - - - - - - - - - - - - Epimerase CMS3_k127_1226958_0 760192.Halhy_0750 0.0 1144.0 COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,1IQJ2@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family cbgA_1 - - - - - - - - - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CMS3_k127_1226958_2 504472.Slin_0735 5.69e-96 324.0 COG1082@1|root,COG1082@2|Bacteria,4NJF5@976|Bacteroidetes,47MRZ@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 CMS3_k127_1226958_1 448385.sce5541 2.56e-175 565.0 2CB1C@1|root,2Z7M2@2|Bacteria,1Q9R6@1224|Proteobacteria,438X5@68525|delta/epsilon subdivisions,2X42J@28221|Deltaproteobacteria,2YY36@29|Myxococcales 28221|Deltaproteobacteria S Transmembrane protein of unknown function (DUF3556) - - - - - - - - - - - - DUF3556 CMS3_k127_1230394_0 926549.KI421517_gene1556 2.84e-142 466.0 COG0210@1|root,COG0210@2|Bacteria,4NDWN@976|Bacteroidetes,47JMH@768503|Cytophagia 976|Bacteroidetes L PFAM UvrD REP helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C CMS3_k127_1230394_1 313606.M23134_08300 4.446e-77 280.0 COG2114@1|root,COG2208@1|root,COG2114@2|Bacteria,COG2208@2|Bacteria,4NEVN@976|Bacteroidetes,47MR3@768503|Cytophagia 976|Bacteroidetes T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - 7TMR-DISM_7TM,Guanylate_cyc,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_1230394_2 365046.Rta_31660 1.077e-05 50.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria,4AC3E@80864|Comamonadaceae 28216|Betaproteobacteria K Bacterial regulatory proteins, crp family crp - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - Crp,HTH_Crp_2,cNMP_binding CMS3_k127_1231170_2 760192.Halhy_3112 7.046e-21 94.0 2AE47@1|root,313XF@2|Bacteria,4NYMZ@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4160) - - - - - - - - - - - - DUF4160 CMS3_k127_1231170_1 760192.Halhy_3113 3.662e-62 218.0 COG3620@1|root,COG3620@2|Bacteria,4NQCR@976|Bacteroidetes,1IUKF@117747|Sphingobacteriia 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 CMS3_k127_1231170_0 1121904.ARBP01000005_gene4578 1.247e-75 259.0 COG1082@1|root,COG1082@2|Bacteria,4NIWS@976|Bacteroidetes,47K4W@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N CMS3_k127_1231521_6 641526.ADIWIN_2307 5.824e-50 179.0 COG3396@1|root,COG3460@1|root,COG3396@2|Bacteria,COG3460@2|Bacteria,4NFJN@976|Bacteroidetes,1HXY6@117743|Flavobacteriia 976|Bacteroidetes Q With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC CMS3_k127_1231521_0 1313421.JHBV01000008_gene4327 4.838e-175 552.0 COG3396@1|root,COG3396@2|Bacteria,4NFJN@976|Bacteroidetes,1IVM8@117747|Sphingobacteriia 976|Bacteroidetes S Phenylacetic acid catabolic protein paaA - 1.14.13.149 ko:K02609 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC CMS3_k127_1231521_2 1122176.KB903532_gene2701 5.293e-124 407.0 COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,1IWHK@117747|Sphingobacteriia 976|Bacteroidetes C Oxidoreductase FAD-binding domain paaE - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 CMS3_k127_1231521_5 1122165.AUHS01000018_gene1946 1.272e-78 273.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,1RY55@1236|Gammaproteobacteria,1JC7E@118969|Legionellales 118969|Legionellales F N-terminal domain of ribose phosphate pyrophosphokinase - - - - - - - - - - - - Pribosyltran,Pribosyltran_N CMS3_k127_1231521_1 616991.JPOO01000001_gene3609 3.97e-144 469.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia,23G8X@178469|Arenibacter 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_1231521_3 1313301.AUGC01000010_gene953 4.786e-80 276.0 COG0705@1|root,COG0705@2|Bacteria,4NS52@976|Bacteroidetes 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_1231521_4 1048983.EL17_16525 1.852e-79 279.0 COG1680@1|root,COG1680@2|Bacteria,4NFMQ@976|Bacteroidetes,47JE6@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_1239036_0 1313421.JHBV01000014_gene3849 0.0 1238.0 COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,1INMI@117747|Sphingobacteriia 976|Bacteroidetes S alpha-2-macroglobulin domain protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl CMS3_k127_1256162_1 1122176.KB903536_gene1756 2.327e-124 400.0 COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1IPIA@117747|Sphingobacteriia 976|Bacteroidetes G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 CMS3_k127_1256162_0 756272.Plabr_2687 1.213e-181 580.0 COG3119@1|root,COG3119@2|Bacteria,2J26D@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - 3.1.6.12 ko:K01135 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00076,M00077 R07823 - ko00000,ko00001,ko00002,ko01000 - - - Sulfatase CMS3_k127_1256162_2 484018.BACPLE_00242 6.314e-52 187.0 COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,2FP46@200643|Bacteroidia,4AMVS@815|Bacteroidaceae 976|Bacteroidetes F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like CMS3_k127_1260471_2 926549.KI421517_gene2586 1.533e-65 232.0 COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,47PN6@768503|Cytophagia 976|Bacteroidetes S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 CMS3_k127_1260471_1 313606.M23134_07240 3.785e-71 243.0 COG0590@1|root,COG0590@2|Bacteria,4NM6I@976|Bacteroidetes,47PAX@768503|Cytophagia 976|Bacteroidetes FJ MafB19-like deaminase - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 CMS3_k127_1260471_3 1120966.AUBU01000001_gene1061 1.413e-18 90.0 COG1669@1|root,COG1669@2|Bacteria,4NV8X@976|Bacteroidetes 976|Bacteroidetes S PFAM Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 CMS3_k127_1260471_0 1304284.L21TH_0837 1.202e-79 275.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,36E47@31979|Clostridiaceae 186801|Clostridia F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 CMS3_k127_1272454_4 1122176.KB903598_gene4693 8.677e-49 201.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4PHZG@976|Bacteroidetes,1IW5N@117747|Sphingobacteriia 976|Bacteroidetes O Pregnancy-associated plasma protein-A - - - - - - - - - - - - CHU_C,Peptidase_M43 CMS3_k127_1272454_6 1121904.ARBP01000044_gene2080 2.799e-09 71.0 COG2353@1|root,COG3210@1|root,COG2353@2|Bacteria,COG3210@2|Bacteria,4NIDX@976|Bacteroidetes,47TZD@768503|Cytophagia 976|Bacteroidetes U YceI-like domain - - - - - - - - - - - - - CMS3_k127_1272454_5 1408433.JHXV01000019_gene1916 7.784e-25 123.0 COG3291@1|root,COG3291@2|Bacteria,4NJYT@976|Bacteroidetes,1IKD0@117743|Flavobacteriia,2PAFR@246874|Cryomorphaceae 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD CMS3_k127_1272454_2 1185876.BN8_00772 1.846e-130 467.0 COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia 976|Bacteroidetes O SprB repeat - - - - - - - - - - - - CHU_C,PKD,SprB,TIG CMS3_k127_1272454_3 867902.Ornrh_1416 7.56e-124 406.0 COG0564@1|root,COG0564@2|Bacteria,4NEV3@976|Bacteroidetes,1HY12@117743|Flavobacteriia 976|Bacteroidetes J Responsible for synthesis of pseudouridine from uracil rluD - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CMS3_k127_1272454_0 1237149.C900_02555 1.31e-205 654.0 COG0578@1|root,COG0578@2|Bacteria,4PKIZ@976|Bacteroidetes,47XKF@768503|Cytophagia 976|Bacteroidetes C C-terminal domain of alpha-glycerophosphate oxidase glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C CMS3_k127_1272454_1 391587.KAOT1_09551 6.021e-192 609.0 COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1HXZD@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family malZ - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31 CMS3_k127_1285389_2 760192.Halhy_1697 3.922e-62 220.0 COG1672@1|root,COG1672@2|Bacteria,4NR06@976|Bacteroidetes 976|Bacteroidetes L Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - CMS3_k127_1285389_1 760192.Halhy_5815 6.476e-99 344.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_1285389_0 143224.JQMD01000002_gene1615 1.084e-107 352.0 COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia 976|Bacteroidetes P Arylsulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C CMS3_k127_128987_2 153948.NAL212_2787 9.879e-33 129.0 2AHT0@1|root,3185H@2|Bacteria,1PZUW@1224|Proteobacteria,2WC28@28216|Betaproteobacteria,373KC@32003|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_128987_0 1265505.ATUG01000001_gene4392 4.422e-49 180.0 2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria,2MNB4@213118|Desulfobacterales 28221|Deltaproteobacteria S DGC domain - - - - - - - - - - - - DGC CMS3_k127_128987_1 1026882.MAMP_01379 3.789e-39 147.0 COG1063@1|root,COG1063@2|Bacteria,1QXQ8@1224|Proteobacteria,1S1AP@1236|Gammaproteobacteria,461ZP@72273|Thiotrichales 72273|Thiotrichales E PFAM Methylene-tetrahydromethanopterin dehydrogenase, N-terminal - - - ko:K10714 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 - R08059 RC00202 ko00000,ko00001,ko01000 - - - Mpt_N CMS3_k127_1290790_4 1121904.ARBP01000003_gene6322 2.653e-78 265.0 COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47TJ9@768503|Cytophagia 976|Bacteroidetes E Pfam:SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_1290790_0 1121904.ARBP01000003_gene6323 0.0 1320.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JHW@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_1290790_1 471854.Dfer_0303 5.044e-184 591.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NIKG@976|Bacteroidetes,47MEK@768503|Cytophagia 976|Bacteroidetes C Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Cytochrom_C,GSDH CMS3_k127_1290790_7 517418.Ctha_0890 3.024e-24 106.0 COG4974@1|root,COG4974@2|Bacteria,1FF1Y@1090|Chlorobi 1090|Chlorobi L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase CMS3_k127_1290790_6 153721.MYP_431 1.269e-31 137.0 COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes,47MHX@768503|Cytophagia 976|Bacteroidetes M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS CMS3_k127_1290790_2 641524.ADICYQ_1862 9.34e-167 541.0 COG3391@1|root,COG3391@2|Bacteria,4NHHU@976|Bacteroidetes,47P02@768503|Cytophagia 976|Bacteroidetes S amine dehydrogenase activity - - - - - - - - - - - - - CMS3_k127_1290790_3 926549.KI421517_gene1735 1.283e-84 301.0 28KW5@1|root,2ZACI@2|Bacteria,4P15K@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1290790_5 1121875.KB907550_gene790 2.78e-69 243.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,1HX7C@117743|Flavobacteriia 976|Bacteroidetes C PFAM Cytochrome C - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2 CMS3_k127_1296932_6 1121904.ARBP01000022_gene3520 2.108e-30 124.0 COG1621@1|root,COG1621@2|Bacteria,4PNCP@976|Bacteroidetes 976|Bacteroidetes G beta-fructofuranosidase activity - - - - - - - - - - - - - CMS3_k127_1296932_2 388413.ALPR1_15804 2.116e-151 490.0 COG0726@1|root,COG0726@2|Bacteria,4NXDC@976|Bacteroidetes,47WVS@768503|Cytophagia 976|Bacteroidetes G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS3_k127_1296932_4 471854.Dfer_1105 1.09e-99 334.0 COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,47JU7@768503|Cytophagia 976|Bacteroidetes H Aldolase/RraA - - - - - - - - - - - - RraA-like CMS3_k127_1296932_3 1121011.AUCB01000005_gene2345 2.013e-112 378.0 COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,1I821@117743|Flavobacteriia,23FKJ@178469|Arenibacter 976|Bacteroidetes S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk CMS3_k127_1296932_0 761193.Runsl_4624 3.239e-250 786.0 COG1501@1|root,COG1501@2|Bacteria,4NH0T@976|Bacteroidetes,47TMI@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolases family 31 - - 3.2.1.177 ko:K01811 - - - - ko00000,ko01000 - GH31 - Glyco_hydro_31 CMS3_k127_1296932_1 880070.Cycma_0098 4.352e-160 515.0 COG1387@1|root,COG1387@2|Bacteria 2|Bacteria E zinc ion binding - - 3.1.3.15 ko:K02347,ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000,ko03400 - - - PHP CMS3_k127_1296932_5 1288963.ADIS_1078 3.547e-44 163.0 COG0521@1|root,COG4198@1|root,COG0521@2|Bacteria,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,47N95@768503|Cytophagia 976|Bacteroidetes H Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 CMS3_k127_1303430_4 1124780.ANNU01000086_gene1363 4.954e-10 60.0 COG2373@1|root,COG4206@1|root,COG2373@2|Bacteria,COG4206@2|Bacteria,4NG2S@976|Bacteroidetes,47K94@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - A2M,A2M_N,A2M_comp,A2M_recep,CarbopepD_reg_2,Plug,Thiol-ester_cl CMS3_k127_1303430_1 1408433.JHXV01000005_gene2337 7.729e-154 495.0 COG0436@1|root,COG0436@2|Bacteria,4NG6G@976|Bacteroidetes,1HY78@117743|Flavobacteriia,2PAA3@246874|Cryomorphaceae 976|Bacteroidetes E PFAM Aminotransferase class I and II aspC - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_1303430_2 485918.Cpin_1902 2.861e-100 335.0 COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia 976|Bacteroidetes H 4-hydroxybenzoate polyprenyltransferase - - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA CMS3_k127_1303430_0 1121904.ARBP01000006_gene3808 9.11e-260 833.0 COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47K15@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 N terminal domain - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_1303430_3 746697.Aeqsu_1421 9.265e-60 214.0 COG2738@1|root,COG2738@2|Bacteria,4NDWG@976|Bacteroidetes,1HXAU@117743|Flavobacteriia 976|Bacteroidetes S zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 CMS3_k127_1304762_2 1124780.ANNU01000025_gene3330 7.514e-238 756.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47MZQ@768503|Cytophagia 976|Bacteroidetes M Transglycosylase - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS3_k127_1304762_0 1237149.C900_03146 0.0 1431.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,47JWU@768503|Cytophagia 976|Bacteroidetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 CMS3_k127_1304762_7 1122621.ATZA01000002_gene1680 7.137e-28 117.0 COG1734@1|root,COG1734@2|Bacteria,4NNID@976|Bacteroidetes,1IS92@117747|Sphingobacteriia 976|Bacteroidetes T Molecular chaperone DnaK dksA - - - - - - - - - - - zf-dskA_traR CMS3_k127_1304762_5 313606.M23134_03182 3.915e-44 171.0 COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,47MEJ@768503|Cytophagia 976|Bacteroidetes M This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 CMS3_k127_1304762_6 1168289.AJKI01000027_gene1367 5.563e-33 135.0 COG0597@1|root,COG0597@2|Bacteria,4NEZN@976|Bacteroidetes,2FS30@200643|Bacteroidia,3XJD6@558415|Marinilabiliaceae 976|Bacteroidetes MU Signal peptidase (SPase) II lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 CMS3_k127_1304762_3 518766.Rmar_2160 6.811e-199 627.0 COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,1FJ3D@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C NADH-ubiquinone oxidoreductase-F iron-sulfur binding region hndC - 1.12.1.3,1.6.5.3 ko:K00335,ko:K18331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB CMS3_k127_1304762_1 761193.Runsl_2790 0.0 1080.0 COG5492@1|root,COG5492@2|Bacteria,4NHMV@976|Bacteroidetes,47M4F@768503|Cytophagia 976|Bacteroidetes N Polysaccharide lyase family 8, super-sandwich domain - - 4.2.2.5 ko:K19049 - - - - ko00000,ko01000 - PL8 - Lyase_8,Lyase_8_C,Lyase_8_N CMS3_k127_1304762_4 1267211.KI669560_gene1467 3.712e-67 233.0 COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,1INM3@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase M61 - - - - - - - - - - - - PDZ_2,Peptidase_M61 CMS3_k127_1310315_2 643867.Ftrac_3409 6.044e-153 497.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFBK@976|Bacteroidetes,47NYZ@768503|Cytophagia 976|Bacteroidetes EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N CMS3_k127_1310315_4 1121897.AUGO01000007_gene441 1.597e-61 219.0 COG2378@1|root,COG2378@2|Bacteria,4NHIC@976|Bacteroidetes,1HZ87@117743|Flavobacteriia,2NSTI@237|Flavobacterium 976|Bacteroidetes K helix_turn_helix, Deoxyribose operon repressor - - - - - - - - - - - - HTH_11,WYL CMS3_k127_1310315_0 1239962.C943_01532 0.0 1117.0 COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia 976|Bacteroidetes E PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N CMS3_k127_1310315_1 1121904.ARBP01000021_gene3558 2.685e-295 922.0 COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes,47XSX@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase, family 20, catalytic domain - - - - - - - - - - - - Glyco_hydro_20b CMS3_k127_1310315_5 1121007.AUML01000010_gene3348 1.397e-52 194.0 28PKG@1|root,2ZC9Y@2|Bacteria,4NNB0@976|Bacteroidetes,1I1TH@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1310315_3 1121904.ARBP01000011_gene1558 8.034e-82 278.0 COG5492@1|root,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes 976|Bacteroidetes N Domain of unknown function (DUF5060) - - - - - - - - - - - - Collagen_bind_2,DUF5060 CMS3_k127_1310739_2 313606.M23134_07807 2.383e-83 293.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,47JQ1@768503|Cytophagia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_7,TPR_8 CMS3_k127_1310739_0 926562.Oweho_0067 7.493e-100 355.0 28HH2@1|root,2Z7ST@2|Bacteria,4NMWR@976|Bacteroidetes,1I1Q4@117743|Flavobacteriia 976|Bacteroidetes M Thiol-activated cytolysin - - - ko:K11031 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - Thiol_cytolysin CMS3_k127_1310739_3 1144319.PMI16_04513 7.888e-23 115.0 COG3209@1|root,COG3209@2|Bacteria,1R1SB@1224|Proteobacteria,2W3D6@28216|Betaproteobacteria 2|Bacteria M Salmonella virulence plasmid 65kDa B protein - - - - - - - - - - - - CHB_HEX_C_1,CotH,Flg_new,Fn3_assoc,LRR_5,LTD,Peptidase_S9,SpvB,TcdB_toxin_midN,VCBS CMS3_k127_1310739_1 748449.Halha_2506 2.955e-99 335.0 COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia 186801|Clostridia S domain protein - - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_1314264_2 929556.Solca_4388 7.208e-60 213.0 COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia 976|Bacteroidetes S phosphoesterase RecJ domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS3_k127_1314264_3 945713.IALB_2102 1.09e-53 192.0 COG0105@1|root,COG0105@2|Bacteria 2|Bacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK CMS3_k127_1314264_0 927677.ALVU02000001_gene2869 5.836e-117 384.0 28IYZ@1|root,2Z8WJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PhyH CMS3_k127_1314264_5 388413.ALPR1_13000 5.426e-05 53.0 COG0135@1|root,COG0135@2|Bacteria,4NMKY@976|Bacteroidetes,47RUF@768503|Cytophagia 976|Bacteroidetes E PFAM N-(5'phosphoribosyl)anthranilate (PRA) isomerase - - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI CMS3_k127_1314264_1 517418.Ctha_0147 1.094e-69 249.0 COG2114@1|root,COG2114@2|Bacteria,1FDUW@1090|Chlorobi 1090|Chlorobi T Adenylate guanylate cyclase - - - - - - - - - - - - Guanylate_cyc CMS3_k127_1314264_4 1239962.C943_01244 9.787e-27 117.0 2ETBD@1|root,33KVB@2|Bacteria,4NSV4@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 CMS3_k127_132534_1 1237149.C900_01760 1.192e-15 84.0 COG4365@1|root,COG4365@2|Bacteria,4NGCF@976|Bacteroidetes,47JYH@768503|Cytophagia 976|Bacteroidetes S Belongs to the BshC family bshC - - ko:K22136 - - - - ko00000 - - - BshC CMS3_k127_132534_0 643867.Ftrac_3407 8.949e-303 940.0 COG0296@1|root,COG0296@2|Bacteria,4NECZ@976|Bacteroidetes,47NPV@768503|Cytophagia 976|Bacteroidetes G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 CMS3_k127_1328494_0 566466.NOR53_3283 1.559e-89 309.0 COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RY0F@1236|Gammaproteobacteria,1J6JX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M Glycosyl transferases group 1 - - - ko:K21001 ko02025,map02025 - - - ko00000,ko00001,ko01003 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4 CMS3_k127_1328494_1 195250.CM001776_gene196 5.232e-12 70.0 COG4424@1|root,COG4424@2|Bacteria,1GH5K@1117|Cyanobacteria,1H3AW@1129|Synechococcus 1117|Cyanobacteria S Sulfotransferase - - - - - - - - - - - - - CMS3_k127_1339274_2 1237149.C900_03649 1.344e-81 295.0 COG2203@1|root,COG3292@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NK8Q@976|Bacteroidetes,47M6U@768503|Cytophagia 976|Bacteroidetes KT PFAM Y_Y_Y domain - - - - - - - - - - - - GAF_2,HATPase_c,HTH_18,HisKA,HisKA_2,Reg_prop,Response_reg,SpoIIE,Y_Y_Y CMS3_k127_1339274_3 880071.Fleli_0516 2.204e-43 169.0 2EIQ0@1|root,33CFG@2|Bacteria,4NZ60@976|Bacteroidetes,47WIN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1339274_1 1270196.JCKI01000003_gene1761 1.23e-92 313.0 COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1IPGY@117747|Sphingobacteriia 976|Bacteroidetes M dTDP-4-dehydrorhamnose reductase rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind CMS3_k127_1339274_0 926549.KI421517_gene2903 2.133e-214 686.0 COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 CMS3_k127_1339274_5 98439.AJLL01000048_gene2941 1.844e-07 63.0 COG0457@1|root,COG0457@2|Bacteria,1G1PV@1117|Cyanobacteria,1JI47@1189|Stigonemataceae 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 CMS3_k127_1339274_6 565034.BHWA1_00970 1.309e-05 57.0 COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes 203691|Spirochaetes S tetratricopeptide repeat lmp1 - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8 CMS3_k127_1339274_4 1121007.AUML01000010_gene3322 4.246e-38 151.0 COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1HWJJ@117743|Flavobacteriia,2YGV1@290174|Aquimarina 976|Bacteroidetes S Alpha-2-macroglobulin family - - - - - - - - - - - - A2M,A2M_N,A2M_N_2,CarbopepD_reg_2 CMS3_k127_1364567_7 118161.KB235918_gene27 0.0005298 45.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria 1117|Cyanobacteria M tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2 CMS3_k127_1364567_0 1189612.A33Q_0629 4.216e-297 974.0 COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4PP4S@976|Bacteroidetes,47YN4@768503|Cytophagia 976|Bacteroidetes KLT AAA ATPase domain - - - - - - - - - - - - AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase CMS3_k127_1364567_2 83406.HDN1F_15650 6.975e-62 223.0 COG0204@1|root,COG0204@2|Bacteria,1RB47@1224|Proteobacteria,1S31I@1236|Gammaproteobacteria 1236|Gammaproteobacteria I COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - - - - - - - - - - Acyltransferase,DAGAT CMS3_k127_1364567_4 1185876.BN8_03356 2.046e-21 104.0 COG4249@1|root,COG4249@2|Bacteria 2|Bacteria S B-1 B cell differentiation - - - - - - - - - - - - Lipase_GDSL_2,Peptidase_C14,Trypsin_2 CMS3_k127_1364567_1 272123.Anacy_0442 1.956e-188 612.0 COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria 2|Bacteria CH Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' - - 1.3.5.5 ko:K02293 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R04786,R04787,R07510,R09652,R09653,R09654 RC01214,RC01958,RC03092,RC03093 ko00000,ko00001,ko00002,ko01000 - - - ADC,Amino_oxidase,NAD_binding_8 CMS3_k127_1364567_5 1121374.KB891576_gene179 1.229e-16 92.0 COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria,1N0QS@1224|Proteobacteria,1RRB9@1236|Gammaproteobacteria 1236|Gammaproteobacteria E NAD(P)-binding Rossmann-like domain - - - - - - - - - - - - ADC,Amino_oxidase,NAD_binding_8 CMS3_k127_1364567_6 290397.Adeh_0777 2.668e-06 59.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales 28221|Deltaproteobacteria GM epimerase dehydratase - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - 3Beta_HSD,Epimerase CMS3_k127_1364567_3 717231.Flexsi_2299 4.613e-41 168.0 COG0661@1|root,COG0661@2|Bacteria,2GEQH@200930|Deferribacteres 200930|Deferribacteres S ABC1 family - - - ko:K03688 - - - - ko00000 - - - ABC1 CMS3_k127_1365809_0 984262.SGRA_1984 1.829e-85 304.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1IXFQ@117747|Sphingobacteriia 976|Bacteroidetes K COG0457 FOG TPR repeat - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_8 CMS3_k127_136736_0 926549.KI421517_gene1137 7.82e-160 514.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia 976|Bacteroidetes L PFAM Helicase conserved C-terminal domain - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N CMS3_k127_136736_1 487796.Flav2ADRAFT_0076 9.832e-124 401.0 COG0623@1|root,COG0623@2|Bacteria,4NEVE@976|Bacteroidetes,1HYEY@117743|Flavobacteriia 976|Bacteroidetes I Enoyl- acyl-carrier-protein reductase NADH fabI - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_1368524_0 153721.MYP_4572 1.368e-126 430.0 COG0760@1|root,COG0760@2|Bacteria,4NGIR@976|Bacteroidetes,47K78@768503|Cytophagia 976|Bacteroidetes O peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 CMS3_k127_1368524_3 1408473.JHXO01000005_gene1648 7.03e-16 88.0 COG0760@1|root,COG0760@2|Bacteria,4NG2P@976|Bacteroidetes,2FMWD@200643|Bacteroidia 976|Bacteroidetes O COG NOG23400 non supervised orthologous group - - - - - - - - - - - - Rotamase_2 CMS3_k127_1368524_2 1279009.ADICEAN_02207 1.969e-82 290.0 COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,47JPW@768503|Cytophagia 976|Bacteroidetes O peptidyl-prolyl isomerase surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N_3 CMS3_k127_1368524_1 1191523.MROS_0169 6.411e-126 410.0 COG0714@1|root,COG0714@2|Bacteria 2|Bacteria KLT Associated with various cellular activities moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 CMS3_k127_1368586_0 926562.Oweho_1991 4.812e-76 284.0 COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,1HZ7Y@117743|Flavobacteriia,2PBDM@246874|Cryomorphaceae 976|Bacteroidetes O PFAM Pregnancy-associated plasma protein-A - - - - - - - - - - - - PKD,Peptidase_M43,fn3 CMS3_k127_1368586_1 929562.Emtol_0700 3.093e-13 75.0 2E5Q2@1|root,330EP@2|Bacteria,4NUMS@976|Bacteroidetes,47SBQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1370968_5 694427.Palpr_0366 2.689e-17 87.0 COG2832@1|root,COG2832@2|Bacteria,4NS6H@976|Bacteroidetes,2FSGM@200643|Bacteroidia,22YP7@171551|Porphyromonadaceae 976|Bacteroidetes S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 CMS3_k127_1370968_0 1492737.FEM08_05270 9.885e-237 755.0 COG0510@1|root,COG1257@1|root,COG0510@2|Bacteria,COG1257@2|Bacteria,4NGN1@976|Bacteroidetes,1INBK@117743|Flavobacteriia,2NYYX@237|Flavobacterium 976|Bacteroidetes I Hydroxymethylglutaryl-coenzyme A reductase - - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - APH,HMG-CoA_red CMS3_k127_1370968_6 1353276.JADR01000008_gene892 4.004e-15 83.0 2EMGK@1|root,33F59@2|Bacteria,4NYBS@976|Bacteroidetes,1I76K@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1370968_2 761193.Runsl_3571 8.683e-81 274.0 COG0652@1|root,COG0652@2|Bacteria,4NMG5@976|Bacteroidetes,47PB6@768503|Cytophagia 976|Bacteroidetes O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase CMS3_k127_1370968_1 880073.Calab_1350 9.372e-88 299.0 COG0484@1|root,COG0484@2|Bacteria,2NQI8@2323|unclassified Bacteria 2|Bacteria O DnaJ molecular chaperone homology domain cbpA - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C CMS3_k127_1370968_3 1313301.AUGC01000001_gene1536 4.114e-45 167.0 COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes 976|Bacteroidetes O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS3_k127_1370968_4 760192.Halhy_5534 6.064e-32 145.0 COG0515@1|root,COG5263@1|root,COG0515@2|Bacteria,COG5263@2|Bacteria,4PNYX@976|Bacteroidetes,1INU8@117747|Sphingobacteriia 976|Bacteroidetes KLT WG containing repeat - - - - - - - - - - - - WG_beta_rep CMS3_k127_1379281_0 1122176.KB903548_gene1207 3.618e-76 264.0 COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,1IP1W@117747|Sphingobacteriia 976|Bacteroidetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase CMS3_k127_1379281_1 1279009.ADICEAN_00515 1.121e-44 176.0 COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_137988_0 1121904.ARBP01000004_gene891 9.816e-253 792.0 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - - - - - - - - - - Metallophos,MetallophosC CMS3_k127_137988_1 1121904.ARBP01000012_gene1178 5.925e-169 541.0 COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,47JGM@768503|Cytophagia 976|Bacteroidetes G COGs COG2133 Glucose sorbosone dehydrogenase - - - - - - - - - - - - Cytochrome_CBB3,GSDH CMS3_k127_137988_4 1267211.KI669560_gene2027 2.475e-33 134.0 COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,1IQ7I@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Cytochrome c, class I - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrom_C,Cytochrome_CBB3 CMS3_k127_137988_3 1123277.KB893173_gene1806 7.043e-38 149.0 COG3495@1|root,COG3495@2|Bacteria,4NMZ8@976|Bacteroidetes,47P8H@768503|Cytophagia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - CMS3_k127_137988_5 1453500.AT05_00610 5.115e-30 123.0 COG3495@1|root,COG3495@2|Bacteria,4NMZ8@976|Bacteroidetes,1I5P9@117743|Flavobacteriia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - CMS3_k127_137988_2 471854.Dfer_3618 1.473e-86 295.0 COG0577@1|root,COG0577@2|Bacteria,4NF60@976|Bacteroidetes,47KE0@768503|Cytophagia 976|Bacteroidetes V ABC-type transport system involved in lipoprotein release permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_1380307_1 760192.Halhy_5520 5.553e-38 152.0 COG1672@1|root,COG1672@2|Bacteria,4NT2R@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - CHAT CMS3_k127_1380307_2 760192.Halhy_5532 2.029e-36 152.0 2AHAR@1|root,317M3@2|Bacteria,4P8RB@976|Bacteroidetes,1IZUZ@117747|Sphingobacteriia 760192.Halhy_5532|- S IMG reference gene - - - - - - - - - - - - - CMS3_k127_1380307_0 760192.Halhy_4332 9.299e-63 239.0 COG1262@1|root,COG1672@1|root,COG3064@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,COG3064@2|Bacteria,4PN7M@976|Bacteroidetes,1IXXU@117747|Sphingobacteriia 976|Bacteroidetes M Membrane - - - - - - - - - - - - - CMS3_k127_138628_4 1122176.KB903539_gene1348 8.216e-88 300.0 COG4714@1|root,COG4714@2|Bacteria,4NEVY@976|Bacteroidetes,1IVI4@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2167) - - - - - - - - - - - - DUF2167 CMS3_k127_138628_1 1121930.AQXG01000002_gene2106 1.199e-168 551.0 COG0464@1|root,COG0464@2|Bacteria,4P1Y0@976|Bacteroidetes 976|Bacteroidetes O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA CMS3_k127_138628_0 1121875.KB907547_gene3288 8.26e-185 581.0 COG5285@1|root,COG5285@2|Bacteria,4NG3B@976|Bacteroidetes,1HWTR@117743|Flavobacteriia 976|Bacteroidetes Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH CMS3_k127_138628_2 1121875.KB907547_gene3289 2.647e-129 418.0 COG2207@1|root,COG2207@2|Bacteria,4NE6T@976|Bacteroidetes,1HX87@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - HTH_18 CMS3_k127_138628_3 1250232.JQNJ01000001_gene1634 3.541e-95 321.0 COG0574@1|root,COG0574@2|Bacteria,4NH4R@976|Bacteroidetes,1HWKY@117743|Flavobacteriia 976|Bacteroidetes G Pyruvate phosphate dikinase - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N CMS3_k127_138873_7 1500890.JQNL01000001_gene576 4.526e-07 59.0 28KMG@1|root,2ZA5X@2|Bacteria,1R8ST@1224|Proteobacteria,1S0CB@1236|Gammaproteobacteria,1XAJG@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - CMS3_k127_138873_6 1406840.Q763_06490 3.377e-10 67.0 2BQRY@1|root,32JNM@2|Bacteria,4NS3X@976|Bacteroidetes,1I9E3@117743|Flavobacteriia,2NWYA@237|Flavobacterium 976|Bacteroidetes S phosphoribosylaminoimidazole-succinocarboxamide synthase - - - - - - - - - - - - - CMS3_k127_138873_3 696281.Desru_0765 6.261e-109 370.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae 186801|Clostridia H Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - ACPS,Carb_kinase,YjeF_N CMS3_k127_138873_4 1313421.JHBV01000042_gene3314 2.015e-84 293.0 COG3081@1|root,COG3081@2|Bacteria,4NFSN@976|Bacteroidetes,1IPSX@117747|Sphingobacteriia 976|Bacteroidetes S 37-kD nucleoid-associated bacterial protein - - - - - - - - - - - - NA37 CMS3_k127_138873_1 760192.Halhy_5001 1.944e-209 659.0 COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,4NG9J@976|Bacteroidetes,1IWMZ@117747|Sphingobacteriia 976|Bacteroidetes I Coenzyme A transferase - - 2.8.3.5,2.8.3.8,2.8.3.9 ko:K01027,ko:K01035 ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R00410,R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans CMS3_k127_138873_0 616991.JPOO01000001_gene4502 1.45e-239 747.0 COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,1HYAT@117743|Flavobacteriia,23G1H@178469|Arenibacter 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal CMS3_k127_138873_2 1202532.FF52_17768 1.738e-129 422.0 COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1HYD5@117743|Flavobacteriia,2NU2A@237|Flavobacterium 976|Bacteroidetes G Arylesterase - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pectate_lyase_3,SGL CMS3_k127_138873_5 929562.Emtol_3354 4.416e-81 273.0 COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,47KU5@768503|Cytophagia 976|Bacteroidetes G PFAM Glycosyl hydrolase family 10 - - 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - Glyco_hydro_10 CMS3_k127_1389697_0 1408813.AYMG01000014_gene1674 3.821e-314 981.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NF9D@976|Bacteroidetes,1IPN0@117747|Sphingobacteriia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 CMS3_k127_1389697_1 643867.Ftrac_1687 1.846e-38 148.0 COG1846@1|root,COG1846@2|Bacteria,4NNK7@976|Bacteroidetes,47QHS@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR CMS3_k127_1389716_0 1313301.AUGC01000003_gene1985 1.444e-222 711.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_1389716_1 7739.XP_002592247.1 3.329e-06 57.0 COG0457@1|root,KOG1840@2759|Eukaryota,39WRG@33154|Opisthokonta,3BCIY@33208|Metazoa,3E68G@33213|Bilateria,48BFJ@7711|Chordata 33208|Metazoa Z Tetratricopeptide repeat - - - - - - - - - - - - DUF294,TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_1398116_3 760192.Halhy_0941 7.218e-143 460.0 COG0438@1|root,COG0438@2|Bacteria,4NEZI@976|Bacteroidetes,1IPPF@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_1398116_2 760192.Halhy_0940 5.73e-178 562.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase CMS3_k127_1398116_1 1385517.N800_12685 7.007e-205 669.0 COG2304@1|root,COG2304@2|Bacteria,1R7H7@1224|Proteobacteria,1SEG0@1236|Gammaproteobacteria 1236|Gammaproteobacteria E von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA,VWA_2 CMS3_k127_1398116_4 1121904.ARBP01000013_gene343 4.094e-121 396.0 COG1210@1|root,COG1210@2|Bacteria,4NF1P@976|Bacteroidetes,47NPD@768503|Cytophagia 976|Bacteroidetes M Nucleotidyl transferase - - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CMS3_k127_1398116_0 926549.KI421517_gene2690 2.166e-286 888.0 COG4284@1|root,COG4284@2|Bacteria,4PNAA@976|Bacteroidetes,47P1V@768503|Cytophagia 976|Bacteroidetes G UTP--glucose-1-phosphate uridylyltransferase - - - - - - - - - - - - UDPGP CMS3_k127_1404990_0 760192.Halhy_3911 7.03e-157 504.0 COG1373@1|root,COG1373@2|Bacteria,4NEMX@976|Bacteroidetes,1IRG9@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_1404990_2 1267211.KI669560_gene431 1.332e-56 207.0 COG5340@1|root,COG5340@2|Bacteria,4NGN9@976|Bacteroidetes,1IVIB@117747|Sphingobacteriia 976|Bacteroidetes K AbiEi antitoxin C-terminal domain - - - - - - - - - - - - AbiEi_1,AbiEi_4 CMS3_k127_1404990_3 1305735.JAFT01000005_gene1347 5.128e-46 170.0 COG2253@1|root,COG2253@2|Bacteria,1R77W@1224|Proteobacteria,2U3HZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii CMS3_k127_1404990_1 411154.GFO_1717 3.652e-107 350.0 COG1062@1|root,COG1062@2|Bacteria,4NF83@976|Bacteroidetes,1HY5N@117743|Flavobacteriia 976|Bacteroidetes C Alcohol dehydrogenase GroES-like domain - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS3_k127_1406538_2 1313301.AUGC01000009_gene990 8.416e-72 248.0 COG0566@1|root,COG0566@2|Bacteria,4NFH3@976|Bacteroidetes 976|Bacteroidetes J Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase CMS3_k127_1406538_0 1185876.BN8_05829 2.459e-113 374.0 COG4857@1|root,COG4857@2|Bacteria,4NHKI@976|Bacteroidetes,47JME@768503|Cytophagia 976|Bacteroidetes S Phosphotransferase enzyme family mtnK - 2.7.1.100 ko:K00899 ko00270,ko01100,map00270,map01100 M00034 R04143 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APH CMS3_k127_1406538_1 700598.Niako_7303 4.925e-109 360.0 COG0667@1|root,COG0667@2|Bacteria,4NHAU@976|Bacteroidetes,1IQA1@117747|Sphingobacteriia 976|Bacteroidetes C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CMS3_k127_1406538_3 504472.Slin_0602 9.351e-44 165.0 COG3356@1|root,COG3356@2|Bacteria,4NJPV@976|Bacteroidetes,47JM2@768503|Cytophagia 976|Bacteroidetes S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk CMS3_k127_1415718_1 641143.HMPREF9331_00588 4.908e-103 344.0 COG1044@1|root,COG1044@2|Bacteria,4NFXA@976|Bacteroidetes,1HXWG@117743|Flavobacteriia,1EQUU@1016|Capnocytophaga 976|Bacteroidetes I UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase lpxD1 - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD CMS3_k127_1415718_0 946077.W5A_02635 0.0 1067.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,1HWN8@117743|Flavobacteriia 976|Bacteroidetes C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase,OmpA CMS3_k127_1415718_2 1123276.KB893246_gene607 3.936e-14 75.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,4NERC@976|Bacteroidetes,47K07@768503|Cytophagia 976|Bacteroidetes K PFAM MerR family regulatory protein - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 CMS3_k127_1418917_4 1313301.AUGC01000007_gene528 1.033e-22 104.0 28PR3@1|root,2ZCD0@2|Bacteria,4NMAF@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1418917_1 742726.HMPREF9448_02619 1.381e-65 231.0 COG0289@1|root,COG0289@2|Bacteria,4NDX2@976|Bacteroidetes,2FNUW@200643|Bacteroidia,22VX2@171551|Porphyromonadaceae 976|Bacteroidetes E Belongs to the DapB family dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N CMS3_k127_1418917_2 755732.Fluta_2910 1.141e-38 166.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1HYK6@117743|Flavobacteriia,2PBIS@246874|Cryomorphaceae 976|Bacteroidetes M OmpA family yiaD - - - - - - - - - - - Gly-zipper_Omp,OmpA CMS3_k127_1418917_0 323259.Mhun_0418 8.988e-78 286.0 COG3291@1|root,arCOG02559@1|root,arCOG02508@2157|Archaea,arCOG02559@2157|Archaea,2XYKK@28890|Euryarchaeota,2NBHR@224756|Methanomicrobia 224756|Methanomicrobia O by modhmm - - - - - - - - - - - - - CMS3_k127_1418917_3 1122226.AUHX01000004_gene1712 7.044e-29 123.0 COG1051@1|root,COG1051@2|Bacteria,4NS9I@976|Bacteroidetes,1HZFF@117743|Flavobacteriia 976|Bacteroidetes F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX CMS3_k127_1419431_2 153721.MYP_2602 8.349e-09 65.0 COG1572@1|root,COG2931@1|root,COG3227@1|root,COG3266@1|root,COG3291@1|root,COG4447@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD,SBBP CMS3_k127_1419431_1 760192.Halhy_0402 3.094e-101 338.0 COG0491@1|root,COG0491@2|Bacteria,4NHG1@976|Bacteroidetes,1IV1T@117747|Sphingobacteriia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_1419431_0 926549.KI421517_gene513 1.106e-278 881.0 COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,47K9H@768503|Cytophagia 976|Bacteroidetes L DNA-directed DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon CMS3_k127_1421780_3 555500.I215_14466 2.015e-87 291.0 COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,1HZE1@117743|Flavobacteriia 976|Bacteroidetes G Alpha-L-arabinofuranosidase - - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C CMS3_k127_1421780_1 1121904.ARBP01000021_gene3618 7.742e-103 341.0 COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,47W9V@768503|Cytophagia 976|Bacteroidetes H Pfam:Methyltransf_6 - - - - - - - - - - - - RraA-like CMS3_k127_1421780_2 994573.T472_0200300 4.633e-90 312.0 COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,36G8D@31979|Clostridiaceae 186801|Clostridia G Trap dicarboxylate transporter, dctm subunit - - - - - - - - - - - - DctM CMS3_k127_1421780_11 572547.Amico_1750 4.372e-07 59.0 COG3090@1|root,COG3090@2|Bacteria,3TB8X@508458|Synergistetes 508458|Synergistetes G PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - - - - - - - - - - DctQ CMS3_k127_1421780_6 698769.JFBD01000005_gene2943 4.74e-50 190.0 COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HB6Q@91061|Bacilli,4C6N2@84406|Virgibacillus 91061|Bacilli G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS3_k127_1421780_4 742735.HMPREF9467_04021 7.978e-86 298.0 COG1228@1|root,COG1228@2|Bacteria,1VB9P@1239|Firmicutes,24MRA@186801|Clostridia 186801|Clostridia Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_1421780_9 1313421.JHBV01000019_gene5344 3.283e-23 111.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_1421780_10 553175.POREN0001_0945 8.11e-10 65.0 COG0457@1|root,COG0457@2|Bacteria,4NP26@976|Bacteroidetes,2FV02@200643|Bacteroidia,230KS@171551|Porphyromonadaceae 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_10,TPR_12,TPR_8 CMS3_k127_1421780_8 1312954.KI914868_gene47 6.051e-35 145.0 COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria,1W9CK@1268|Micrococcaceae 201174|Actinobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31,1.1.1.411 ko:K00020,ko:K08319 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS3_k127_1421780_5 871963.Desdi_0799 4.678e-53 198.0 COG1143@1|root,COG1143@2|Bacteria,1UIF0@1239|Firmicutes,25EKC@186801|Clostridia,2657D@186807|Peptococcaceae 186801|Clostridia C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4 CMS3_k127_1421780_7 401526.TcarDRAFT_2289 2.884e-38 151.0 2AV93@1|root,31M00@2|Bacteria,1V94N@1239|Firmicutes,4H7KF@909932|Negativicutes 909932|Negativicutes - - - - - - - - - - - - - - - CMS3_k127_1421780_0 1191523.MROS_2634 1.379e-125 413.0 2B7NJ@1|root,32VIJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1434368_3 926556.Echvi_0454 9.196e-13 78.0 COG0457@1|root,COG0457@2|Bacteria,4NQ3P@976|Bacteroidetes,47YJC@768503|Cytophagia 976|Bacteroidetes S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_6 CMS3_k127_1434368_2 153721.MYP_4089 8.788e-22 103.0 COG1595@1|root,COG1595@2|Bacteria,4NX8R@976|Bacteroidetes,47PIG@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2 CMS3_k127_1434368_0 1223410.KN050846_gene1809 5.928e-139 456.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia 976|Bacteroidetes M Membrane protein involved in D-alanine export - - - - - - - - - - - - MBOAT CMS3_k127_1434368_1 385682.AFSL01000083_gene1160 3.903e-99 336.0 COG0204@1|root,COG0204@2|Bacteria,4NGR9@976|Bacteroidetes,2FM79@200643|Bacteroidia,3XIU9@558415|Marinilabiliaceae 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_1434368_4 1121904.ARBP01000006_gene3779 2.518e-07 54.0 COG2831@1|root,COG2831@2|Bacteria,4PMYI@976|Bacteroidetes,47YEW@768503|Cytophagia 976|Bacteroidetes U Protein of unknown function (DUF3570) - - - - - - - - - - - - DUF3570 CMS3_k127_143466_2 1123037.AUDE01000027_gene2118 1.43e-50 189.0 2AZZY@1|root,31SA0@2|Bacteria,4NRJ3@976|Bacteroidetes,1I3N5@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_143466_0 313603.FB2170_01532 1.142e-98 331.0 COG0745@1|root,COG0745@2|Bacteria,4NIKR@976|Bacteroidetes,1HYDZ@117743|Flavobacteriia 976|Bacteroidetes KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Trans_reg_C CMS3_k127_143466_1 313603.FB2170_15638 5.74e-55 200.0 arCOG02770@1|root,33PR0@2|Bacteria,4P237@976|Bacteroidetes,1I7R8@117743|Flavobacteriia 976|Bacteroidetes S CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_143466_3 272123.Anacy_2814 2.017e-32 128.0 COG2337@1|root,COG2337@2|Bacteria,1G7SY@1117|Cyanobacteria,1HNTB@1161|Nostocales 1117|Cyanobacteria L Toxic component of a toxin-antitoxin (TA) module - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin CMS3_k127_1436263_2 485918.Cpin_4076 1.235e-40 164.0 COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria,4NI29@976|Bacteroidetes 976|Bacteroidetes T Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,TPR_12,TPR_8 CMS3_k127_1436263_0 1121904.ARBP01000017_gene5122 9.035e-229 716.0 COG4102@1|root,COG4102@2|Bacteria,4NJB8@976|Bacteroidetes,47U5K@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_1436263_1 1121904.ARBP01000017_gene5121 7.153e-124 411.0 COG2010@1|root,COG2010@2|Bacteria,4NJ8T@976|Bacteroidetes,47TEN@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 CMS3_k127_1450498_1 468059.AUHA01000003_gene1801 6.901e-55 199.0 COG4850@1|root,COG4850@2|Bacteria,4NFZ6@976|Bacteroidetes,1IT86@117747|Sphingobacteriia 976|Bacteroidetes S Uncharacterized conserved protein (DUF2183) - - - - - - - - - - - - DUF2183 CMS3_k127_1450498_2 1173023.KE650771_gene655 4.224e-49 187.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria 1117|Cyanobacteria O PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2 CMS3_k127_1450498_0 760192.Halhy_0880 1.125e-105 351.0 COG1760@1|root,COG1760@2|Bacteria,4NJF4@976|Bacteroidetes 976|Bacteroidetes E Serine dehydratase alpha chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta CMS3_k127_1456262_4 1121938.AUDY01000009_gene2146 8.911e-06 52.0 2DZKI@1|root,32VD4@2|Bacteria,1VC45@1239|Firmicutes,4HKMY@91061|Bacilli,3NE5K@45667|Halobacillus 91061|Bacilli - - - - - - - - - - - - - - - CMS3_k127_1456262_2 926562.Oweho_0101 6.464e-63 226.0 COG0030@1|root,COG0030@2|Bacteria,4NERB@976|Bacteroidetes,1HXMG@117743|Flavobacteriia,2PAPI@246874|Cryomorphaceae 976|Bacteroidetes J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD CMS3_k127_1456262_1 869213.JCM21142_93910 3.018e-119 392.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,47MC9@768503|Cytophagia 976|Bacteroidetes H Belongs to the PdxA family pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA CMS3_k127_1456262_3 1122176.KB903531_gene2958 6.016e-46 183.0 COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes 976|Bacteroidetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - CMS3_k127_1456262_0 761193.Runsl_2810 7.898e-137 445.0 COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family alkH - 1.2.1.3,1.2.1.68 ko:K00128,ko:K00154 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_1456550_1 1185876.BN8_04332 1.285e-235 740.0 COG2866@1|root,COG2866@2|Bacteria,4NF3D@976|Bacteroidetes,47UEQ@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 CMS3_k127_1456550_3 314230.DSM3645_07870 4.822e-140 454.0 COG2755@1|root,COG2755@2|Bacteria,2IWSK@203682|Planctomycetes 203682|Planctomycetes E N-terminus of Esterase_SGNH_hydro-type - - - - - - - - - - - - GxDLY,Lipase_GDSL_3 CMS3_k127_1456550_6 1122176.KB903552_gene3706 5.43e-48 176.0 COG1522@1|root,COG1522@2|Bacteria,4NPYG@976|Bacteroidetes 976|Bacteroidetes K helix_turn_helix ASNC type - - - ko:K03718 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24 CMS3_k127_1456550_5 1122176.KB903552_gene3707 1.414e-64 226.0 COG2095@1|root,COG2095@2|Bacteria,4NG94@976|Bacteroidetes,1IRXN@117747|Sphingobacteriia 976|Bacteroidetes U PFAM MarC family integral membrane protein marC - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC CMS3_k127_1456550_2 518766.Rmar_1343 1.638e-180 578.0 COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,1FJ4W@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O Belongs to the ClpA ClpB family clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR CMS3_k127_1456550_0 861299.J421_6091 0.0 1244.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1ZSS1@142182|Gemmatimonadetes 142182|Gemmatimonadetes O Tricorn protease homolog - - - ko:K08676 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ CMS3_k127_1456550_4 1121481.AUAS01000007_gene1174 6.42e-66 237.0 COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47QTP@768503|Cytophagia 976|Bacteroidetes C PFAM Cytochrome C - - - - - - - - - - - - Cytochrom_C CMS3_k127_1456550_7 204773.HEAR2583 3.14e-16 90.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4727Q@75682|Oxalobacteraceae 28216|Betaproteobacteria M Belongs to the ompA family ompA - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA CMS3_k127_1458057_1 886377.Murru_2683 1.399e-91 306.0 COG1028@1|root,COG1028@2|Bacteria,4NH6Y@976|Bacteroidetes,1HXA4@117743|Flavobacteriia 976|Bacteroidetes IQ short-chain dehydrogenase - - - - - - - - - - - - adh_short_C2 CMS3_k127_1458057_4 118161.KB235922_gene2599 2.488e-23 101.0 COG2361@1|root,COG2361@2|Bacteria 2|Bacteria S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 CMS3_k127_1458057_3 118161.KB235922_gene2598 4.056e-36 139.0 COG1669@1|root,COG1669@2|Bacteria,1G8U6@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 CMS3_k127_1458057_0 1121904.ARBP01000003_gene6277 3.348e-224 705.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase CMS3_k127_1458057_2 288000.BBta_2828 1.167e-74 265.0 COG0348@1|root,COG0348@2|Bacteria,1R8G0@1224|Proteobacteria,2U46K@28211|Alphaproteobacteria,3JX79@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - - CMS3_k127_1463921_0 760192.Halhy_1667 6.518e-43 165.0 2FKHX@1|root,34C53@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1463921_1 388413.ALPR1_01095 1.304e-23 117.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - AraC_binding,HTH_18 CMS3_k127_1467214_3 1189612.A33Q_2948 3.59e-44 167.0 COG4977@1|root,COG4977@2|Bacteria,4NHHE@976|Bacteroidetes,47N5H@768503|Cytophagia 976|Bacteroidetes K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI CMS3_k127_1467214_1 1499967.BAYZ01000139_gene156 5.703e-121 396.0 COG2055@1|root,COG2055@2|Bacteria 2|Bacteria C Belongs to the LDH2 MDH2 oxidoreductase family dlgD - 1.1.1.130 ko:K08092 ko00040,ko00053,map00040,map00053 - R02637,R02639 RC00238 ko00000,ko00001,ko01000 - - - Ldh_2 CMS3_k127_1467214_0 234267.Acid_1816 0.0 1243.0 COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria 2|Bacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran CMS3_k127_1467214_2 1122927.KB895414_gene5055 2.373e-50 186.0 COG1708@1|root,COG1708@2|Bacteria,1V3BY@1239|Firmicutes,4IRIQ@91061|Bacilli,276T2@186822|Paenibacillaceae 91061|Bacilli S domain protein - - - - - - - - - - - - - CMS3_k127_1472136_1 1124780.ANNU01000037_gene91 1.172e-103 344.0 COG4974@1|root,COG4974@2|Bacteria,4NI44@976|Bacteroidetes,47KRE@768503|Cytophagia 976|Bacteroidetes L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_5,Phage_int_SAM_5,Phage_integrase CMS3_k127_1472136_0 1484460.JSWG01000008_gene1892 3.648e-137 455.0 COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HZIA@117743|Flavobacteriia 976|Bacteroidetes Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 CMS3_k127_1472136_3 1485545.JQLW01000005_gene1055 2.413e-15 80.0 COG2608@1|root,COG2608@2|Bacteria,1NIWX@1224|Proteobacteria 1224|Proteobacteria P Heavy-metal-associated domain - - - - - - - - - - - - HMA CMS3_k127_1472136_2 1249975.JQLP01000005_gene746 1.539e-22 98.0 2DB6Y@1|root,2Z7IS@2|Bacteria,4NGTV@976|Bacteroidetes,1I11P@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1473521_0 1121904.ARBP01000022_gene3481 8.49e-252 791.0 COG2133@1|root,COG4244@1|root,COG2133@2|Bacteria,COG4244@2|Bacteria,4NG6K@976|Bacteroidetes,47K0Y@768503|Cytophagia 976|Bacteroidetes G Protein of unknown function (DUF1549) - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 CMS3_k127_1473521_1 1408473.JHXO01000005_gene1730 5.86e-29 120.0 COG0204@1|root,COG0204@2|Bacteria,4NQF1@976|Bacteroidetes,2FXSZ@200643|Bacteroidia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_1479497_4 1089547.KB913013_gene1635 9.516e-65 226.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,47K61@768503|Cytophagia 976|Bacteroidetes I AMP-binding enzyme - - - - - - - - - - - - AMP-binding CMS3_k127_1479497_5 1239962.C943_01967 7.574e-59 213.0 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,47JZP@768503|Cytophagia 976|Bacteroidetes O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen ccmG - - - - - - - - - - - AhpC-TSA,DUF4369 CMS3_k127_1479497_7 1124780.ANNU01000016_gene1824 5.67e-30 123.0 COG2197@1|root,COG2197@2|Bacteria,4PKIY@976|Bacteroidetes 976|Bacteroidetes T PFAM Response regulator receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_1479497_9 1121904.ARBP01000003_gene6364 1.04e-26 125.0 COG0793@1|root,COG0793@2|Bacteria,4NGGJ@976|Bacteroidetes,47PB5@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family S41 - - - - - - - - - - - - Peptidase_S41 CMS3_k127_1479497_8 869213.JCM21142_400 3.206e-29 128.0 2D6WA@1|root,32TMZ@2|Bacteria,4NU16@976|Bacteroidetes,47VUX@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 CMS3_k127_1479497_0 869213.JCM21142_401 4.568e-122 408.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47UYK@768503|Cytophagia 976|Bacteroidetes N transport system involved in gliding motility, auxiliary component - - - - - - - - - - - - ABC_transp_aux CMS3_k127_1479497_3 1408473.JHXO01000016_gene1933 3.711e-80 273.0 COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,2FT12@200643|Bacteroidia 976|Bacteroidetes S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 CMS3_k127_1479497_1 869213.JCM21142_403 1.627e-117 385.0 COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47TXK@768503|Cytophagia 976|Bacteroidetes V ATPases associated with a variety of cellular activities gldA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_1479497_2 1121859.KB890738_gene3180 3.68e-107 361.0 COG0772@1|root,COG0772@2|Bacteria,4NDZD@976|Bacteroidetes,47JVQ@768503|Cytophagia 976|Bacteroidetes D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE CMS3_k127_1479497_6 880071.Fleli_2929 1.772e-39 149.0 COG0768@1|root,COG0768@2|Bacteria,4NE47@976|Bacteroidetes,47JSM@768503|Cytophagia 976|Bacteroidetes M Penicillin-binding protein, dimerisation domain mrdA - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase CMS3_k127_1482839_0 1122176.KB903543_gene589 0.0 1067.0 COG4206@1|root,COG4206@2|Bacteria,4PM6D@976|Bacteroidetes,1J101@117747|Sphingobacteriia 976|Bacteroidetes H Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_1482839_1 1122176.KB903543_gene590 1.365e-69 243.0 COG3712@1|root,COG3712@2|Bacteria,4NMA2@976|Bacteroidetes,1IS2K@117747|Sphingobacteriia 976|Bacteroidetes PT PFAM FecR protein - - - - - - - - - - - - DUF4974,FecR CMS3_k127_1485944_4 1313421.JHBV01000035_gene2498 2.421e-48 180.0 COG4995@1|root,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1IXZE@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_7 CMS3_k127_1485944_1 1120966.AUBU01000010_gene2856 9.783e-238 743.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47N92@768503|Cytophagia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_1485944_0 1122176.KB903619_gene5294 2.313e-320 986.0 COG2303@1|root,COG2303@2|Bacteria,4NEHP@976|Bacteroidetes,1IPAY@117747|Sphingobacteriia 976|Bacteroidetes E Oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N CMS3_k127_1485944_3 1122176.KB903619_gene5295 3.225e-101 334.0 2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1ISGE@117747|Sphingobacteriia 976|Bacteroidetes S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_1485944_2 1121904.ARBP01000057_gene3452 4.114e-182 582.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47MX6@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - Laminin_G_3,PSCyt1,PSCyt2,PSD1 CMS3_k127_1488794_1 1120966.AUBU01000001_gene1061 3.647e-16 83.0 COG1669@1|root,COG1669@2|Bacteria,4NV8X@976|Bacteroidetes 976|Bacteroidetes S PFAM Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 CMS3_k127_1488794_0 1122179.KB890415_gene1976 1.673e-152 494.0 COG3291@1|root,COG3291@2|Bacteria,4PN6M@976|Bacteroidetes,1IW1H@117747|Sphingobacteriia 976|Bacteroidetes S Chondroitinase B - - - - - - - - - - - - Chondroitinas_B CMS3_k127_1488794_2 344747.PM8797T_00392 6.201e-13 74.0 COG1506@1|root,COG1506@2|Bacteria,2J52Y@203682|Planctomycetes 203682|Planctomycetes E Dienelactone hydrolase family - - - - - - - - - - - - - CMS3_k127_1490476_5 504472.Slin_1742 1.04e-33 132.0 COG1012@1|root,COG1012@2|Bacteria,4NGHD@976|Bacteroidetes,47KZA@768503|Cytophagia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family alkH - 1.2.1.3,1.2.1.68 ko:K00128,ko:K00154 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_1490476_3 1217648.F933_00753 4.257e-45 173.0 COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,1SD9D@1236|Gammaproteobacteria,3NMNZ@468|Moraxellaceae 1236|Gammaproteobacteria S Family of unknown function (DUF695) - - - - - - - - - - - - DUF695,RraB CMS3_k127_1490476_4 5888.CAK74865 3.986e-37 159.0 COG5253@1|root,KOG0229@2759|Eukaryota,3ZD66@5878|Ciliophora 2759|Eukaryota T Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - ko:K14972 - - - - ko00000,ko03036 - - - IQ,MORN CMS3_k127_1490476_2 984262.SGRA_3093 3.279e-69 243.0 COG1192@1|root,COG1192@2|Bacteria,4NGFE@976|Bacteroidetes,1IW93@117747|Sphingobacteriia 976|Bacteroidetes D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 CMS3_k127_1490476_1 1305737.JAFX01000001_gene2856 5.565e-70 243.0 COG0662@1|root,COG0662@2|Bacteria,4NFU2@976|Bacteroidetes,47PIW@768503|Cytophagia 976|Bacteroidetes G Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC - 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO CMS3_k127_1490476_0 760192.Halhy_4721 2.798e-151 515.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NVRP@976|Bacteroidetes 976|Bacteroidetes E Carboxypeptidase - - - - - - - - - - - - - CMS3_k127_1496026_3 1071073.KI530538_gene349 1.665e-53 199.0 COG3393@1|root,COG3393@2|Bacteria,1V1XP@1239|Firmicutes,4HG3K@91061|Bacilli,1ZR7Q@1386|Bacillus 91061|Bacilli S FR47-like protein - - - ko:K06976 - - - - ko00000 - - - Acetyltransf_1,FR47 CMS3_k127_1496026_1 211165.AJLN01000145_gene1322 3.276e-188 599.0 COG2730@1|root,COG2730@2|Bacteria,1G3EZ@1117|Cyanobacteria 1117|Cyanobacteria G Protein of unknown function (DUF4038) - - - - - - - - - - - - Collagen_bind_2,DUF4038 CMS3_k127_1496026_0 756272.Plabr_3141 9.326e-257 817.0 COG0591@1|root,COG3055@1|root,COG0591@2|Bacteria,COG3055@2|Bacteria,2IX6M@203682|Planctomycetes 203682|Planctomycetes E Sodium:solute symporter family - - - - - - - - - - - - Kelch_1,SSF CMS3_k127_1496026_2 1185876.BN8_03437 4.954e-147 475.0 COG1373@1|root,COG1373@2|Bacteria,4NGFI@976|Bacteroidetes,47U2B@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_150086_4 616991.JPOO01000003_gene2627 7.442e-47 171.0 COG2308@1|root,COG2308@2|Bacteria,4NG4D@976|Bacteroidetes,1HY5C@117743|Flavobacteriia 976|Bacteroidetes S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - CMS3_k127_150086_2 616991.JPOO01000003_gene2628 7.369e-106 349.0 COG0518@1|root,COG0518@2|Bacteria,4NGC3@976|Bacteroidetes,1HZTP@117743|Flavobacteriia 976|Bacteroidetes F GMP synthase - - - - - - - - - - - - GATase CMS3_k127_150086_0 641526.ADIWIN_4061 5.013e-170 541.0 COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,1HZNS@117743|Flavobacteriia 976|Bacteroidetes S ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity ybdK - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 CMS3_k127_150086_1 616991.JPOO01000003_gene2630 2.323e-162 516.0 COG0189@1|root,COG0189@2|Bacteria,4NFK1@976|Bacteroidetes,1HZS6@117743|Flavobacteriia 976|Bacteroidetes HJ Glutathione synthase - - - - - - - - - - - - - CMS3_k127_150086_3 1392490.JHZX01000001_gene2783 2.254e-93 308.0 COG2382@1|root,COG2382@2|Bacteria,4NGIA@976|Bacteroidetes,1HYJV@117743|Flavobacteriia 976|Bacteroidetes P esterase - - - - - - - - - - - - Abhydrolase_1,Esterase CMS3_k127_1511977_2 694427.Palpr_0469 7.694e-111 361.0 COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,2FS6Q@200643|Bacteroidia,22XWC@171551|Porphyromonadaceae 976|Bacteroidetes S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane CMS3_k127_1511977_1 760192.Halhy_5004 2.482e-117 389.0 COG0596@1|root,COG0599@1|root,COG0596@2|Bacteria,COG0599@2|Bacteria,4NF5F@976|Bacteroidetes,1IYR3@117747|Sphingobacteriia 976|Bacteroidetes S Ndr family - - 3.1.1.24,4.1.1.44 ko:K01055,ko:K14727 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991,R03470 RC00825,RC00938 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,CMD CMS3_k127_1511977_3 1237149.C900_03635 5.141e-12 66.0 2C1XD@1|root,340CH@2|Bacteria,4P45P@976|Bacteroidetes 976|Bacteroidetes S Putative lumazine-binding - - - - - - - - - - - - Lumazine_bd_2 CMS3_k127_1511977_0 880070.Cycma_3424 1.474e-250 788.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47NEI@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_1511996_1 530564.Psta_3244 1.873e-34 146.0 COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes 203682|Planctomycetes G Pfam:DUF303 - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA CMS3_k127_1511996_2 1191523.MROS_1591 1.255e-30 134.0 COG3525@1|root,COG3525@2|Bacteria 2|Bacteria G beta-N-acetylhexosaminidase activity - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b CMS3_k127_1511996_0 1499967.BAYZ01000115_gene2928 1.779e-98 332.0 COG1680@1|root,COG1680@2|Bacteria,2NRI6@2323|unclassified Bacteria 2|Bacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_1517456_3 880070.Cycma_2101 1.144e-13 78.0 292HI@1|root,2ZQ1P@2|Bacteria,4P784@976|Bacteroidetes,47WQ0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1517456_2 228410.NE0622 1.58e-21 100.0 COG0662@1|root,COG0662@2|Bacteria,1RFTK@1224|Proteobacteria,2WG1F@28216|Betaproteobacteria,374QB@32003|Nitrosomonadales 28216|Betaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 CMS3_k127_1517456_1 1121904.ARBP01000004_gene1143 9.602e-133 429.0 COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,47JU7@768503|Cytophagia 976|Bacteroidetes H Aldolase/RraA - - - - - - - - - - - - RraA-like CMS3_k127_1517456_0 1121904.ARBP01000005_gene4607 9.439e-133 430.0 COG3386@1|root,COG3386@2|Bacteria,4NIMX@976|Bacteroidetes,47KMQ@768503|Cytophagia 976|Bacteroidetes G PFAM SMP-30 Gluconolaconase - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL CMS3_k127_1524732_2 1124780.ANNU01000023_gene3220 1.132e-72 248.0 COG0111@1|root,COG0560@1|root,COG0111@2|Bacteria,COG0560@2|Bacteria,4NDVN@976|Bacteroidetes,47MQ2@768503|Cytophagia 976|Bacteroidetes EH PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,HAD CMS3_k127_1524732_0 1121904.ARBP01000010_gene2331 3.734e-97 334.0 COG2755@1|root,COG2755@2|Bacteria,4NFVN@976|Bacteroidetes,47Q1S@768503|Cytophagia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 CMS3_k127_1524732_1 269798.CHU_2176 8.48e-89 310.0 COG2244@1|root,COG2244@2|Bacteria,4NPGZ@976|Bacteroidetes,47PWY@768503|Cytophagia 976|Bacteroidetes S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CMS3_k127_1524732_3 1405.DJ92_2326 2.391e-16 87.0 COG0438@1|root,COG0438@2|Bacteria,1UYBT@1239|Firmicutes,4HCSK@91061|Bacilli,1ZE7T@1386|Bacillus 91061|Bacilli M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 CMS3_k127_1537767_3 313594.PI23P_07580 7.315e-51 189.0 COG0438@1|root,COG0438@2|Bacteria,4NHPJ@976|Bacteroidetes,1I6B2@117743|Flavobacteriia,3VW47@52959|Polaribacter 976|Bacteroidetes M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_1537767_0 1250278.JQNQ01000001_gene2294 1.527e-70 244.0 COG2227@1|root,COG2227@2|Bacteria,4NM91@976|Bacteroidetes,1HZAR@117743|Flavobacteriia 976|Bacteroidetes H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - - CMS3_k127_1537767_1 1392490.JHZX01000001_gene3344 1.676e-62 234.0 COG2244@1|root,COG2244@2|Bacteria,4NEVQ@976|Bacteroidetes,1HYFW@117743|Flavobacteriia 976|Bacteroidetes S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CMS3_k127_1537767_2 765420.OSCT_1844 3.005e-54 196.0 COG3467@1|root,COG3467@2|Bacteria 2|Bacteria T pyridoxamine 5'-phosphate - - - ko:K07005 - - - - ko00000 - - - Putative_PNPOx,Pyridox_ox_2 CMS3_k127_1537767_4 984262.SGRA_0735 4.543e-31 126.0 COG3682@1|root,COG3682@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - Penicillinase_R CMS3_k127_1542652_0 324925.Ppha_0527 3.33e-125 409.0 COG2089@1|root,COG2089@2|Bacteria,1FD73@1090|Chlorobi 1090|Chlorobi H PFAM N-acetylneuraminic acid synthase - - 2.5.1.101 ko:K18430 ko00520,map00520 - R10304 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF CMS3_k127_1542652_1 929556.Solca_4308 1.79e-121 400.0 COG0381@1|root,COG0381@2|Bacteria,4NFTG@976|Bacteroidetes,1IQ4A@117747|Sphingobacteriia 976|Bacteroidetes M UDP-N-acetylglucosamine 2-epimerase - - 3.2.1.184 ko:K18429 ko00520,map00520 - R10187 RC00005,RC00288 ko00000,ko00001,ko01000 - - - Epimerase_2 CMS3_k127_1542652_2 313606.M23134_02011 1.349e-52 192.0 COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,47RT7@768503|Cytophagia 976|Bacteroidetes S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep,Hexapep_2 CMS3_k127_1542652_3 1077285.AGDG01000032_gene4424 2.678e-05 52.0 COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,2FPXJ@200643|Bacteroidia,4ANIW@815|Bacteroidaceae 976|Bacteroidetes M Nucleotidyl transferase gmhB - 2.7.7.71 ko:K15669 ko00540,map00540 - R09772 RC00002 ko00000,ko00001,ko01000 - - - CBS,NTP_transferase CMS3_k127_1544048_1 1408473.JHXO01000004_gene187 9.334e-80 271.0 COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,2FM7Z@200643|Bacteroidia 976|Bacteroidetes G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim CMS3_k127_1544048_7 449673.BACSTE_00387 8.907e-08 55.0 2A0YE@1|root,30P3N@2|Bacteria,4PBMI@976|Bacteroidetes,2FZ89@200643|Bacteroidia,4AUWQ@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1544048_0 762903.Pedsa_2104 1.848e-133 445.0 COG0616@1|root,COG0616@2|Bacteria,4NES1@976|Bacteroidetes,1IP6H@117747|Sphingobacteriia 976|Bacteroidetes OU signal peptide peptidase SppA, 67K type sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 CMS3_k127_1544048_4 1279009.ADICEAN_00080 1.147e-32 132.0 COG0801@1|root,COG0801@2|Bacteria,4NGE8@976|Bacteroidetes,47QG8@768503|Cytophagia 976|Bacteroidetes H TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK,dNK CMS3_k127_1544048_6 1279009.ADICEAN_02902 1.103e-26 120.0 2DBER@1|root,2Z8TN@2|Bacteria,4NK2P@976|Bacteroidetes,47P45@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1544048_2 504472.Slin_1748 7.227e-38 151.0 COG0500@1|root,COG2226@2|Bacteria,4NSPB@976|Bacteroidetes,47RD0@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_12,Methyltransf_2,Methyltransf_25 CMS3_k127_1544048_3 641143.HMPREF9331_00535 8.945e-33 136.0 COG0596@1|root,COG0596@2|Bacteria,4PKKR@976|Bacteroidetes,1IJBZ@117743|Flavobacteriia,1ERUP@1016|Capnocytophaga 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6,UPF0227 CMS3_k127_1544048_5 1286632.P278_13470 5.811e-31 124.0 COG0691@1|root,COG0691@2|Bacteria,4NNJU@976|Bacteroidetes,1I191@117743|Flavobacteriia 976|Bacteroidetes O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB CMS3_k127_1548635_0 1123248.KB893314_gene3542 9.487e-116 379.0 COG2303@1|root,COG2303@2|Bacteria,4NHJT@976|Bacteroidetes,1IRDW@117747|Sphingobacteriia 976|Bacteroidetes E FAD dependent oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N CMS3_k127_1548635_2 929713.NIASO_01205 1.262e-43 166.0 2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,1ISA1@117747|Sphingobacteriia 976|Bacteroidetes S (twin-arginine translocation) pathway signal - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_1548635_3 1116472.MGMO_97c00180 1.881e-11 66.0 2CYM7@1|root,32T4F@2|Bacteria,1N2CG@1224|Proteobacteria,1SQJ2@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_1548635_1 1250232.JQNJ01000001_gene3217 1.329e-82 287.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process pelC - - ko:K21008 ko02025,map02025 - - - ko00000,ko00001 - - - LpoB CMS3_k127_1559537_7 1122176.KB903534_gene2221 2.52e-106 347.0 COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,1INQS@117747|Sphingobacteriia 976|Bacteroidetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_1559537_8 1121930.AQXG01000008_gene206 1.25e-101 346.0 COG0845@1|root,COG0845@2|Bacteria,4NDUH@976|Bacteroidetes,1IPZS@117747|Sphingobacteriia 976|Bacteroidetes M Efflux transporter, RND family, MFP subunit - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS3_k127_1559537_12 1122176.KB903536_gene1769 2.074e-48 181.0 COG3897@1|root,COG3897@2|Bacteria,4P696@976|Bacteroidetes,1IZ1E@117747|Sphingobacteriia 976|Bacteroidetes S Lysine methyltransferase - - - - - - - - - - - - Methyltransf_16 CMS3_k127_1559537_13 1123278.KB893546_gene4984 2.839e-26 118.0 COG0810@1|root,COG1629@1|root,COG4219@1|root,COG0810@2|Bacteria,COG1629@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,47M7Q@768503|Cytophagia 976|Bacteroidetes KMT PFAM BlaR1 peptidase M56 - - - - - - - - - - - - CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C CMS3_k127_1559537_3 742767.HMPREF9456_01921 6.172e-136 439.0 COG1023@1|root,COG1023@2|Bacteria,4PM5B@976|Bacteroidetes,2G10Y@200643|Bacteroidia,2327N@171551|Porphyromonadaceae 976|Bacteroidetes G 6-phosphogluconate dehydrogenase, C-terminal domain - - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 CMS3_k127_1559537_0 927658.AJUM01000042_gene1750 1.249e-220 696.0 COG0364@1|root,COG0364@2|Bacteria,4NE59@976|Bacteroidetes,2FNER@200643|Bacteroidia,3XIQC@558415|Marinilabiliaceae 976|Bacteroidetes G Glucose-6-phosphate dehydrogenase, NAD binding domain zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N CMS3_k127_1559537_9 1408473.JHXO01000005_gene1501 5.541e-81 276.0 COG0363@1|root,COG0363@2|Bacteria,4NGB9@976|Bacteroidetes,2FNZF@200643|Bacteroidia 976|Bacteroidetes G 6-phosphogluconolactonase pgl - 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso CMS3_k127_1559537_1 313606.M23134_05249 2.921e-166 532.0 COG1304@1|root,COG1304@2|Bacteria,4NEBK@976|Bacteroidetes,47P2H@768503|Cytophagia 976|Bacteroidetes C FMN-dependent dehydrogenase lldD - 1.1.2.3,1.13.12.4 ko:K00101,ko:K00467 ko00620,ko01100,map00620,map01100 - R00196,R00319 RC00044,RC01312 ko00000,ko00001,ko01000 - - - FMN_dh CMS3_k127_1559537_6 643867.Ftrac_2463 6.739e-116 385.0 COG0644@1|root,COG0644@2|Bacteria,4NE67@976|Bacteroidetes,47M1U@768503|Cytophagia 976|Bacteroidetes C FAD binding domain fixC - - - - - - - - - - - FAD_binding_3,Lycopene_cycl,SE,Trp_halogenase CMS3_k127_1559537_11 1237149.C900_01543 1.451e-52 194.0 COG0500@1|root,COG2226@2|Bacteria,4NM9E@976|Bacteroidetes,47PMX@768503|Cytophagia 976|Bacteroidetes Q Methyltransferase - - - - - - - - - - - - Methyltransf_25,Methyltransf_31 CMS3_k127_1559537_5 984262.SGRA_1404 2.453e-130 425.0 COG3424@1|root,COG3424@2|Bacteria,4NDZU@976|Bacteroidetes,1IPW6@117747|Sphingobacteriia 976|Bacteroidetes Q Chalcone and stilbene synthases, C-terminal domain bcsA - - - - - - - - - - - Chal_sti_synt_C,Chal_sti_synt_N,FAE1_CUT1_RppA CMS3_k127_1559537_10 439235.Dalk_1753 1.631e-72 254.0 COG0300@1|root,COG0623@1|root,COG0300@2|Bacteria,COG0623@2|Bacteria,1R090@1224|Proteobacteria,43CRU@68525|delta/epsilon subdivisions,2X7ZF@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CMS3_k127_1559537_2 1280946.HY29_07030 7.408e-157 535.0 COG3250@1|root,COG3250@2|Bacteria,1NU94@1224|Proteobacteria,2UNUI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G alpha-L-rhamnosidase - - - - - - - - - - - - Glyco_hydro_106 CMS3_k127_1559537_4 153721.MYP_760 1.089e-132 431.0 COG0438@1|root,COG0438@2|Bacteria,4PKQN@976|Bacteroidetes,47K56@768503|Cytophagia 976|Bacteroidetes M PFAM glycogen synthase - - 2.4.1.11 ko:K00693 ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931 - R00292 RC00005 ko00000,ko00001,ko01000,ko01003 - GT3 - Glycogen_syn CMS3_k127_1563259_4 504472.Slin_6132 2.115e-32 128.0 COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_1563259_6 484018.BACPLE_00352 7.552e-06 55.0 COG3637@1|root,COG3637@2|Bacteria,4NW6Y@976|Bacteroidetes,2G2EB@200643|Bacteroidia,4AQTI@815|Bacteroidaceae 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl CMS3_k127_1563259_2 1122176.KB903532_gene2680 6.018e-71 247.0 COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1IQFC@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - Gly-zipper_Omp,OmpA,PD40 CMS3_k127_1563259_5 1123248.KB893318_gene4192 8.844e-15 79.0 2DTGN@1|root,33K97@2|Bacteria,4NZIF@976|Bacteroidetes,1IU43@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1563259_1 643867.Ftrac_1055 4.457e-221 711.0 COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47JRC@768503|Cytophagia 976|Bacteroidetes S PFAM peptidase S45 penicillin amidase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase CMS3_k127_1563259_3 525373.HMPREF0766_14031 5.82e-43 159.0 COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1IT1Q@117747|Sphingobacteriia 976|Bacteroidetes S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn CMS3_k127_1563259_0 1124780.ANNU01000023_gene3243 1.356e-320 989.0 COG0187@1|root,COG0187@2|Bacteria,4NF18@976|Bacteroidetes,47JS9@768503|Cytophagia 976|Bacteroidetes L Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CMS3_k127_1571350_4 123214.PERMA_1578 4.884e-14 80.0 COG3769@1|root,COG3769@2|Bacteria 2|Bacteria S mannosylglycerate metabolic process yedP GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,2.7.1.31,3.1.3.70 ko:K05947,ko:K07026,ko:K15918 ko00051,ko00260,ko00561,ko00630,ko01100,ko01110,ko01130,ko01200,map00051,map00260,map00561,map00630,map01100,map01110,map01130,map01200 M00532 R01514,R05768,R05790 RC00002,RC00005,RC00017,RC00397,RC02748 ko00000,ko00001,ko00002,ko01000,ko01003 - - - Hydrolase_3 CMS3_k127_1571350_5 886379.AEWI01000065_gene2308 7.176e-07 53.0 2BFRA@1|root,329K3@2|Bacteria,4NR20@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1571350_1 1121904.ARBP01000003_gene6319 4.09e-169 539.0 2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,47N0C@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Phenol_MetA_deg CMS3_k127_1571350_3 1288963.ADIS_1364 1.872e-66 241.0 COG1312@1|root,COG1312@2|Bacteria,4NIMS@976|Bacteroidetes,47JVK@768503|Cytophagia 976|Bacteroidetes G D-mannonate dehydratase (UxuA) - - 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - UxuA CMS3_k127_1571350_2 485917.Phep_0335 4.156e-122 403.0 COG4454@1|root,COG4454@2|Bacteria,4PN5Y@976|Bacteroidetes,1IVEJ@117747|Sphingobacteriia 976|Bacteroidetes P PFAM Copper binding proteins, plastocyanin azurin family - - - - - - - - - - - - Copper-bind CMS3_k127_1571350_0 485917.Phep_0336 2.415e-197 627.0 COG2133@1|root,COG2133@2|Bacteria,4NI97@976|Bacteroidetes,1IWTQ@117747|Sphingobacteriia 976|Bacteroidetes G pyrroloquinoline quinone binding - - - - - - - - - - - - GSDH CMS3_k127_158305_2 641524.ADICYQ_5972 2.036e-71 244.0 COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,47JM9@768503|Cytophagia 976|Bacteroidetes L PFAM MgsA AAA ATPase C terminal ycaJ - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CMS3_k127_158305_1 649349.Lbys_3392 2.913e-138 458.0 COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,47MKB@768503|Cytophagia 976|Bacteroidetes C TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M CMS3_k127_158305_4 700598.Niako_6215 0.0002412 49.0 2C1KT@1|root,33DVE@2|Bacteria,4NY76@976|Bacteroidetes,1IUDH@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_158305_3 1392488.JHZY01000004_gene2195 3.035e-25 112.0 COG0845@1|root,COG0845@2|Bacteria,4NSWM@976|Bacteroidetes,1I499@117743|Flavobacteriia,2XJMH@283735|Leeuwenhoekiella 976|Bacteroidetes M Protein of unknown function (DUF3347) - - - - - - - - - - - - DUF3347 CMS3_k127_158305_0 760192.Halhy_0663 0.0 1277.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_158631_5 1122176.KB903552_gene3689 8.629e-20 98.0 COG2972@1|root,COG2972@2|Bacteria,4NF45@976|Bacteroidetes 976|Bacteroidetes T PFAM Signal transduction histidine kinase, internal region - - - - - - - - - - - - His_kinase,TPR_12,TPR_2,TPR_7,TPR_8 CMS3_k127_158631_4 929562.Emtol_3988 8.788e-44 165.0 COG0572@1|root,COG0572@2|Bacteria,4NUJQ@976|Bacteroidetes,47RCM@768503|Cytophagia 976|Bacteroidetes F uridine kinase - - - - - - - - - - - - - CMS3_k127_158631_3 743722.Sph21_2364 1.972e-46 172.0 COG0597@1|root,COG0597@2|Bacteria,4NNP3@976|Bacteroidetes,1ISWW@117747|Sphingobacteriia 976|Bacteroidetes M This protein specifically catalyzes the removal of signal peptides from prolipoproteins - - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 CMS3_k127_158631_1 1122176.KB903541_gene289 1.597e-88 300.0 COG3021@1|root,COG3021@2|Bacteria,4PMEX@976|Bacteroidetes,1J10Q@117747|Sphingobacteriia 976|Bacteroidetes S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos CMS3_k127_158631_0 616991.JPOO01000001_gene4180 2.011e-161 513.0 COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,1HYBZ@117743|Flavobacteriia,23G7B@178469|Arenibacter 976|Bacteroidetes G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_1587733_0 1288963.ADIS_0500 7.213e-190 618.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47K5R@768503|Cytophagia 976|Bacteroidetes P TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_1593263_2 700598.Niako_4782 2.756e-14 85.0 COG2304@1|root,COG2304@2|Bacteria,4P2H3@976|Bacteroidetes,1IXAA@117747|Sphingobacteriia 976|Bacteroidetes S von Willebrand factor type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA CMS3_k127_1593263_0 1250006.JHZZ01000001_gene3309 4.725e-135 441.0 COG1078@1|root,COG1078@2|Bacteria,4NE1T@976|Bacteroidetes,1HXQF@117743|Flavobacteriia,3VV9K@52959|Polaribacter 976|Bacteroidetes S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06885 - - - - ko00000 - - - HD CMS3_k127_1593263_3 1408473.JHXO01000001_gene2058 2.026e-13 73.0 COG0730@1|root,COG0730@2|Bacteria,4NH6M@976|Bacteroidetes,2FSUD@200643|Bacteroidia 976|Bacteroidetes S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS3_k127_1593263_1 983545.Glaag_1348 6.021e-55 197.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,467A8@72275|Alteromonadaceae 1236|Gammaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS3_k127_1595218_3 1408473.JHXO01000006_gene1025 1.332e-77 262.0 COG0652@1|root,COG0652@2|Bacteria,4NKQ7@976|Bacteroidetes,2FSSH@200643|Bacteroidia 976|Bacteroidetes O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase CMS3_k127_1595218_2 1121930.AQXG01000008_gene205 6.531e-116 381.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPDG@117747|Sphingobacteriia 976|Bacteroidetes T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_1595218_6 1122137.AQXF01000001_gene3102 2.021e-06 58.0 2CIYD@1|root,2ZEMW@2|Bacteria,1P6YZ@1224|Proteobacteria,2UY20@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_1595218_0 1121904.ARBP01000004_gene877 3.845e-169 542.0 COG0477@1|root,COG2814@2|Bacteria,4NG5F@976|Bacteroidetes,47P1A@768503|Cytophagia 976|Bacteroidetes EGP BT1 family ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 CMS3_k127_1595218_1 1121904.ARBP01000004_gene1128 1.963e-149 492.0 COG1472@1|root,COG1472@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 N terminal domain - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_1595218_7 926549.KI421517_gene1574 0.0001643 45.0 COG3698@1|root,COG3698@2|Bacteria,4NMNC@976|Bacteroidetes,47PCD@768503|Cytophagia 976|Bacteroidetes S Phosphodiester glycosidase - - - - - - - - - - - - NAGPA CMS3_k127_1595218_5 1499967.BAYZ01000104_gene3652 2.336e-08 66.0 292ZH@1|root,2ZQGW@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1595218_4 700598.Niako_1274 7.913e-26 113.0 COG1752@1|root,COG1752@2|Bacteria,4NMUK@976|Bacteroidetes,1ISPD@117747|Sphingobacteriia 976|Bacteroidetes S Phospholipase, patatin family - - - ko:K07001 - - - - ko00000 - - - Patatin CMS3_k127_1600739_0 1250006.JHZZ01000001_gene2235 2.551e-305 950.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,1HXUN@117743|Flavobacteriia,3VX3M@52959|Polaribacter 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_1600739_1 1089547.KB913013_gene4668 8.179e-256 806.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes 976|Bacteroidetes P TonB-linked outer membrane protein, SusC RagA family - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_1609087_1 1211813.CAPH01000009_gene131 1.602e-44 167.0 COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,2FNR3@200643|Bacteroidia 976|Bacteroidetes S Endonuclease exonuclease phosphatase family - - - - - - - - - - - - Exo_endo_phos CMS3_k127_1609087_2 880070.Cycma_4777 1.434e-16 87.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - CarboxypepD_reg,MORN_2,Plug,TonB_C CMS3_k127_1609087_3 1219045.BV98_003622 0.0009772 47.0 COG0810@1|root,COG0810@2|Bacteria,1NH16@1224|Proteobacteria,2UKYU@28211|Alphaproteobacteria,2K637@204457|Sphingomonadales 204457|Sphingomonadales U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_1609087_0 411477.PARMER_01576 5.355e-251 792.0 COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FNRT@200643|Bacteroidia,22ZMF@171551|Porphyromonadaceae 976|Bacteroidetes G Glycosyl hydrolase family 92 - - - - - - - - - - - - Glyco_hydro_92 CMS3_k127_1613060_0 984262.SGRA_3992 1.334e-91 332.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - BSP,CHU_C,CarbopepD_reg_2,PKD,SprB CMS3_k127_1614376_2 1348583.ATLH01000022_gene2293 6.785e-37 141.0 COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes,1HWP3@117743|Flavobacteriia,1F85B@104264|Cellulophaga 976|Bacteroidetes F HAMAP Histidine biosynthesis HisG, ATP phosphoribosyltransferase, subgroup hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C CMS3_k127_1614376_0 925409.KI911562_gene2911 2.509e-168 539.0 COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,1IQWR@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh CMS3_k127_1614376_1 1288963.ADIS_0888 1.774e-127 417.0 COG0079@1|root,COG0079@2|Bacteria,4NEDI@976|Bacteroidetes,47N2S@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_1614376_3 1120968.AUBX01000009_gene209 3.181e-12 67.0 COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,47J9I@768503|Cytophagia 976|Bacteroidetes E belongs to the imidazoleglycerol-phosphate dehydratase family hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_like,IGPD,PNK3P CMS3_k127_1614386_1 313596.RB2501_04020 1.035e-82 294.0 COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia 976|Bacteroidetes KT regulator - - - - - - - - - - - - GerE,Reg_prop,Y_Y_Y CMS3_k127_1614386_0 760192.Halhy_5472 5.807e-221 696.0 COG1672@1|root,COG1672@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - AAA-ATPase_like,AAA_35,PDDEXK_3 CMS3_k127_1614386_4 1120965.AUBV01000008_gene1943 1.379e-07 58.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,47KTC@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_1614386_2 313595.P700755_002091 8.392e-28 115.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1HYQ4@117743|Flavobacteriia,4C46R@83612|Psychroflexus 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_1614386_3 1123278.KB893422_gene1590 3.386e-10 60.0 COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,47MBR@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_1617004_2 1121481.AUAS01000005_gene2063 5.139e-112 364.0 COG1082@1|root,COG1082@2|Bacteria,4NHMP@976|Bacteroidetes,47NUC@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase domain protein TIM barrel - - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 CMS3_k127_1617004_0 1250232.JQNJ01000001_gene2708 0.0 1057.0 COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,1HZIM@117743|Flavobacteriia 976|Bacteroidetes S Beta-L-arabinofuranosidase, GH127 - - - - - - - - - - - - Glyco_hydro_127 CMS3_k127_1617004_1 761193.Runsl_4210 4.111e-124 404.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NKGP@976|Bacteroidetes,47M97@768503|Cytophagia 976|Bacteroidetes C pyrroloquinoline quinone binding - - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_1639914_1 1279009.ADICEAN_02512 1.182e-63 225.0 COG0564@1|root,COG0564@2|Bacteria,4NFS8@976|Bacteroidetes,47KV5@768503|Cytophagia 976|Bacteroidetes J Pseudouridine synthase rluC - 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 CMS3_k127_1639914_4 497965.Cyan7822_3021 2.953e-22 109.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G7ID@1117|Cyanobacteria,3KHZI@43988|Cyanothece 1117|Cyanobacteria O Peptidase S1 and S6 chymotrypsin Hap - - - - - - - - - - - - GUN4,TPR_1,TPR_8,Trypsin_2 CMS3_k127_1639914_2 880071.Fleli_0379 1.203e-60 214.0 COG0290@1|root,COG0290@2|Bacteria,4NIZ5@976|Bacteroidetes,47PC6@768503|Cytophagia 976|Bacteroidetes J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N CMS3_k127_1639914_3 247490.KSU1_A0003 1.726e-54 199.0 COG4221@1|root,COG4221@2|Bacteria 2|Bacteria IQ oxidoreductase activity - - - - - - - - - - - - adh_short CMS3_k127_1639914_0 1305737.JAFX01000001_gene1074 5.507e-247 769.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,47MA2@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD CMS3_k127_1643096_3 13035.Dacsa_3036 5.127e-05 46.0 2C9PJ@1|root,32RPM@2|Bacteria,1G7Z4@1117|Cyanobacteria 1117|Cyanobacteria S PFAM XisI protein - - - - - - - - - - - - XisI CMS3_k127_1643096_0 1122179.KB890447_gene351 2.008e-193 616.0 COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,1IUM7@117747|Sphingobacteriia 976|Bacteroidetes S prohibitin homologues yqiK - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot CMS3_k127_1643096_2 1122176.KB903544_gene784 2.788e-31 126.0 COG0714@1|root,COG0714@2|Bacteria,4NPWR@976|Bacteroidetes,1IXGZ@117747|Sphingobacteriia 976|Bacteroidetes S SPTR ATPase associated with various cellular activities AAA_5 - - - - - - - - - - - - AAA CMS3_k127_1646889_0 1313301.AUGC01000016_gene854 3.046e-85 296.0 COG2885@1|root,COG2885@2|Bacteria,4NHWF@976|Bacteroidetes 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_1646889_3 272562.CA_C0753 1.623e-16 92.0 COG4639@1|root,COG4639@2|Bacteria,1V0TW@1239|Firmicutes,248CJ@186801|Clostridia,36FWH@31979|Clostridiaceae 186801|Clostridia S AAA domain - - - - - - - - - - - - AAA_33,HD CMS3_k127_1646889_1 386415.NT01CX_1475 3.122e-74 269.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36EGF@31979|Clostridiaceae 186801|Clostridia L DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes dbpA - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C CMS3_k127_1646889_2 1237149.C900_02704 3.138e-22 98.0 COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes,47XM3@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_1655481_2 1121085.AUCI01000007_gene1221 5.253e-50 199.0 COG0745@1|root,COG4251@1|root,COG5002@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1UMIM@1239|Firmicutes,4ITVY@91061|Bacilli,1ZSDG@1386|Bacillus 91061|Bacilli T 7TMR-DISM extracellular 2 - - - ko:K20971 ko02025,map02025 - - - ko00000,ko00001,ko01001,ko02022 - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Response_reg CMS3_k127_1655481_5 1392498.JQLH01000001_gene2778 7.736e-08 54.0 COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia,2PGHH@252356|Maribacter 976|Bacteroidetes P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec CMS3_k127_1655481_1 1392498.JQLH01000001_gene2778 1.078e-55 207.0 COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia,2PGHH@252356|Maribacter 976|Bacteroidetes P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec CMS3_k127_1655481_0 1121875.KB907549_gene1733 7.94e-224 711.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes 976|Bacteroidetes O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CMS3_k127_1655481_3 237368.SCABRO_02885 2.631e-27 111.0 COG1064@1|root,COG1064@2|Bacteria,2IY4H@203682|Planctomycetes 203682|Planctomycetes C alcohol dehydrogenase - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS3_k127_1663582_3 1089550.ATTH01000001_gene1896 2.803e-86 296.0 COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M GDP-mannose 4,6 dehydratase - - 4.1.1.35,5.1.3.2,5.1.3.7 ko:K01784,ko:K02473,ko:K08678 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R01384,R02984 RC00289,RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd CMS3_k127_1663582_0 1237149.C900_04235 5.135e-260 820.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,47KTE@768503|Cytophagia 976|Bacteroidetes J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 CMS3_k127_1663582_5 1120965.AUBV01000007_gene2674 1.984e-32 127.0 COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,47R7H@768503|Cytophagia 976|Bacteroidetes J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 CMS3_k127_1663582_2 755732.Fluta_2440 1.018e-179 572.0 COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,1HWP1@117743|Flavobacteriia,2PAIG@246874|Cryomorphaceae 976|Bacteroidetes F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt CMS3_k127_1663582_6 641524.ADICYQ_5288 1.728e-24 106.0 COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes,47R73@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS CMS3_k127_1663582_4 1189612.A33Q_0300 4.228e-64 224.0 COG0735@1|root,COG0735@2|Bacteria,4NM8S@976|Bacteroidetes,47P99@768503|Cytophagia 976|Bacteroidetes P Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR CMS3_k127_1663582_1 1356852.N008_16755 1.497e-245 767.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,47JYW@768503|Cytophagia 976|Bacteroidetes O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 CMS3_k127_1668316_9 926562.Oweho_1534 1.126e-24 109.0 COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,1HXZM@117743|Flavobacteriia 976|Bacteroidetes K AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_1668316_7 980584.AFPB01000138_gene2656 9.03e-91 313.0 COG0373@1|root,COG0373@2|Bacteria,4NFTY@976|Bacteroidetes,1HX42@117743|Flavobacteriia,4066M@61432|unclassified Flavobacteriaceae 976|Bacteroidetes H Glutamyl-tRNAGlu reductase, N-terminal domain hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,GlutR_dimer,Shikimate_DH CMS3_k127_1668316_8 1123035.ARLA01000028_gene2024 7.517e-72 253.0 COG0181@1|root,COG0181@2|Bacteria,4NHH4@976|Bacteroidetes,1HXKZ@117743|Flavobacteriia,4C2PA@83612|Psychroflexus 976|Bacteroidetes H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - HEM4,Porphobil_deam,Porphobil_deamC CMS3_k127_1668316_4 886377.Murru_1488 3.641e-136 441.0 COG0407@1|root,COG0407@2|Bacteria,4NEQ7@976|Bacteroidetes,1HY0P@117743|Flavobacteriia 976|Bacteroidetes H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D CMS3_k127_1668316_5 926562.Oweho_1539 6.173e-125 407.0 COG0408@1|root,COG0408@2|Bacteria,4NFZS@976|Bacteroidetes,1HXJH@117743|Flavobacteriia,2PBDS@246874|Cryomorphaceae 976|Bacteroidetes H PFAM Coproporphyrinogen III oxidase hemF - 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas CMS3_k127_1668316_3 700598.Niako_5724 3.578e-140 452.0 COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1INPZ@117747|Sphingobacteriia 976|Bacteroidetes H Belongs to the ALAD family hemB - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD CMS3_k127_1668316_2 926562.Oweho_1542 1.589e-190 604.0 COG0001@1|root,COG0001@2|Bacteria,4NDXG@976|Bacteroidetes,1HWQS@117743|Flavobacteriia,2PAE8@246874|Cryomorphaceae 976|Bacteroidetes H Aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_1668316_0 1121904.ARBP01000017_gene5118 1.474e-320 1002.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47MZ7@768503|Cytophagia 976|Bacteroidetes E Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 CMS3_k127_1668316_6 1121904.ARBP01000019_gene2809 1.22e-124 410.0 COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,47UBF@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_1668316_1 1121904.ARBP01000013_gene342 1.162e-243 762.0 COG4284@1|root,COG4284@2|Bacteria,4PNAA@976|Bacteroidetes,47P1V@768503|Cytophagia 976|Bacteroidetes G UTP--glucose-1-phosphate uridylyltransferase - - - - - - - - - - - - UDPGP CMS3_k127_1670563_2 1121481.AUAS01000018_gene427 6.905e-91 301.0 COG0521@1|root,COG0521@2|Bacteria,4PKAT@976|Bacteroidetes 976|Bacteroidetes H Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 CMS3_k127_1670563_0 1121904.ARBP01000019_gene2778 9.891e-178 571.0 COG3419@1|root,COG3419@2|Bacteria,4NGV9@976|Bacteroidetes,47MMR@768503|Cytophagia 976|Bacteroidetes NU Tfp pilus assembly protein tip-associated adhesin - - - - - - - - - - - - PQQ,PQQ_2 CMS3_k127_1670563_1 1288963.ADIS_3043 3.474e-148 478.0 COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,47KYS@768503|Cytophagia 976|Bacteroidetes S COGs COG4299 conserved - - - - - - - - - - - - DUF5009 CMS3_k127_1670563_3 240016.ABIZ01000001_gene3310 1.385e-60 214.0 COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia 74201|Verrucomicrobia G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - BNR_2,VCBS CMS3_k127_1678757_3 984262.SGRA_3163 1.731e-07 55.0 28HHD@1|root,2Z7T3@2|Bacteria,4NGWB@976|Bacteroidetes,1ISCP@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF3810) - - - - - - - - - - - - DUF3810 CMS3_k127_1678757_2 700598.Niako_1930 4.039e-38 153.0 COG1595@1|root,COG1595@2|Bacteria,4NMK4@976|Bacteroidetes 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2 CMS3_k127_1678757_0 1279009.ADICEAN_00656 2.268e-228 728.0 COG0497@1|root,COG0497@2|Bacteria,4PMJC@976|Bacteroidetes,47YHC@768503|Cytophagia 976|Bacteroidetes L Peptidase S46 - - - - - - - - - - - - Peptidase_S46 CMS3_k127_1678757_1 313606.M23134_04091 3.498e-129 424.0 COG0809@1|root,COG0809@2|Bacteria,4NDZ5@976|Bacteroidetes,47KMT@768503|Cytophagia 976|Bacteroidetes J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth CMS3_k127_1678757_4 649638.Trad_0258 0.0007743 49.0 COG0501@1|root,COG0501@2|Bacteria 2|Bacteria O metalloendopeptidase activity - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48 CMS3_k127_1683707_3 743525.TSC_c02810 2.468e-43 162.0 COG1373@1|root,COG1373@2|Bacteria,1WIG0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_1683707_1 1267535.KB906767_gene473 1.158e-75 270.0 28JXN@1|root,30T38@2|Bacteria,3Y61P@57723|Acidobacteria 57723|Acidobacteria S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS CMS3_k127_1683707_4 649638.Trad_2822 5.368e-23 106.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase_3 CMS3_k127_1683707_6 1158318.ATXC01000001_gene948 2.798e-05 48.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - CarbopepD_reg_2,TonB_2,TonB_C CMS3_k127_1683707_0 309807.SRU_0277 3.952e-223 704.0 COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJX9@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family sglT - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_1683707_2 1121904.ARBP01000001_gene5556 5.886e-73 256.0 COG0613@1|root,COG0613@2|Bacteria,4PMUK@976|Bacteroidetes 976|Bacteroidetes S PHP domain protein - - - - - - - - - - - - - CMS3_k127_1683707_5 929562.Emtol_3334 4.986e-09 67.0 COG3568@1|root,COG3568@2|Bacteria,4NHXV@976|Bacteroidetes,47NJC@768503|Cytophagia 976|Bacteroidetes S PFAM Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos CMS3_k127_1686541_1 1288963.ADIS_1259 9.011e-81 278.0 COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes 976|Bacteroidetes P Pfam Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_1686541_0 1121904.ARBP01000004_gene1094 1.737e-105 345.0 COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_1698738_0 1047013.AQSP01000142_gene240 1.062e-255 803.0 COG3533@1|root,COG3533@2|Bacteria,2NNW0@2323|unclassified Bacteria 2|Bacteria S Beta-L-arabinofuranosidase, GH127 - - - ko:K09955 - - - - ko00000 - - - F5_F8_type_C,Glyco_hydro_127 CMS3_k127_1698738_4 1336803.PHEL49_0143 3.324e-59 214.0 COG1226@1|root,2Z7ZD@2|Bacteria,4NYV9@976|Bacteroidetes,1IBMD@117743|Flavobacteriia 976|Bacteroidetes P Ion transport protein - - - - - - - - - - - - Ion_trans CMS3_k127_1698738_1 1121373.KB903627_gene2966 4.888e-224 730.0 COG0823@1|root,COG3227@1|root,COG0823@2|Bacteria,COG3227@2|Bacteria,4NF8H@976|Bacteroidetes,47MX4@768503|Cytophagia 976|Bacteroidetes E Thermolysin metallopeptidase, catalytic domain npr - 3.4.24.28 ko:K01400 - - - - ko00000,ko01000,ko01002 - - - FTP,MAM,PepSY,Peptidase_M4,Peptidase_M4_C,fn3 CMS3_k127_1698738_6 1123278.KB893546_gene4981 1.128e-13 76.0 2E13P@1|root,32WJ2@2|Bacteria,4NTGM@976|Bacteroidetes,47RAF@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1698738_5 1288963.ADIS_3102 2.619e-29 128.0 COG0596@1|root,COG0596@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - - CMS3_k127_1698738_2 468059.AUHA01000002_gene166 1.262e-157 515.0 COG4166@1|root,COG4166@2|Bacteria,4NFT5@976|Bacteroidetes,1IRBF@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 CMS3_k127_1698738_3 1288963.ADIS_1169 3.388e-82 278.0 COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,47JM3@768503|Cytophagia 976|Bacteroidetes D PFAM CobQ CobB MinD ParA nucleotide binding domain soj - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 CMS3_k127_1704355_2 1185876.BN8_01451 2.905e-14 78.0 COG0577@1|root,COG0577@2|Bacteria,4NJBI@976|Bacteroidetes,47MP8@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_1704355_1 504472.Slin_0949 1.573e-31 126.0 COG1695@1|root,COG1695@2|Bacteria,4NQ31@976|Bacteroidetes,47UWR@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_1704355_0 760192.Halhy_3456 2.524e-91 307.0 COG1218@1|root,COG1218@2|Bacteria,4NFHY@976|Bacteroidetes,1ISXY@117747|Sphingobacteriia 976|Bacteroidetes P COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P CMS3_k127_1704355_3 1137281.D778_00655 1.198e-11 64.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,1HXE2@117743|Flavobacteriia 976|Bacteroidetes C Thioredoxin reductase trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS3_k127_1707088_0 1396418.BATQ01000075_gene651 3.498e-149 484.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity neu - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2,Laminin_G_3 CMS3_k127_1707088_1 1386089.N865_10495 1.342e-81 278.0 COG1182@1|root,COG1182@2|Bacteria,2I9P0@201174|Actinobacteria,4FID3@85021|Intrasporangiaceae 201174|Actinobacteria C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 CMS3_k127_1707088_4 1173027.Mic7113_1142 1.517e-07 58.0 COG5421@1|root,COG5421@2|Bacteria,1G02P@1117|Cyanobacteria,1H9BK@1150|Oscillatoriales 1117|Cyanobacteria L COGs COG5421 Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF4277 CMS3_k127_1707088_3 1121889.AUDM01000008_gene843 4.912e-15 80.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1I6TA@117743|Flavobacteriia 976|Bacteroidetes S ATPase domain predominantly from Archaea - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_1707088_2 1434325.AZQN01000004_gene1899 1.803e-54 204.0 2BQ9X@1|root,32J4V@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1713102_0 743722.Sph21_1620 6.045e-42 168.0 COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,1IQ7X@117747|Sphingobacteriia 976|Bacteroidetes D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS_C CMS3_k127_1713102_2 290317.Cpha266_0086 0.0003582 51.0 COG1572@1|root,COG1572@2|Bacteria,1FEDB@1090|Chlorobi 1090|Chlorobi S cell adhesion involved in biofilm formation - - - - - - - - - - - - - CMS3_k127_1713102_1 1122176.KB903531_gene2825 7.05e-22 106.0 2FG80@1|root,3484C@2|Bacteria,4P5E2@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_171547_3 143224.JQMD01000002_gene3415 8.748e-36 139.0 COG0438@1|root,COG0438@2|Bacteria,4NGFN@976|Bacteroidetes 976|Bacteroidetes M Glycosyltransferase, group 1 family - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_171547_1 944480.ATUV01000001_gene1415 4.935e-76 272.0 COG0438@1|root,COG0438@2|Bacteria,1QFQQ@1224|Proteobacteria,42MC8@68525|delta/epsilon subdivisions,2X1Z6@28221|Deltaproteobacteria,2M7H8@213113|Desulfurellales 28221|Deltaproteobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_171547_0 143224.JQMD01000002_gene3414 1.447e-124 409.0 COG0438@1|root,COG0438@2|Bacteria,4NPX0@976|Bacteroidetes 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_171547_2 755732.Fluta_0213 5.243e-40 150.0 COG0451@1|root,COG0451@2|Bacteria,4NDX8@976|Bacteroidetes,1I1CM@117743|Flavobacteriia 976|Bacteroidetes M Male sterility protein - - 5.1.3.10 ko:K12454 ko00520,map00520 - R04266 RC00528 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd CMS3_k127_1715999_3 1168034.FH5T_01205 2.161e-30 124.0 COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,2FQT6@200643|Bacteroidia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 CMS3_k127_1715999_5 1415778.JQMM01000001_gene764 0.0001569 48.0 COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,1RMC2@1236|Gammaproteobacteria,1J4W7@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation aceK GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 ko:K00906 - - - - ko00000,ko01000 - - - AceK CMS3_k127_1715999_1 1123057.P872_23980 7.65e-74 258.0 COG3217@1|root,COG3217@2|Bacteria,4NG33@976|Bacteroidetes,47PMH@768503|Cytophagia 976|Bacteroidetes S beta barrel domain - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N CMS3_k127_1715999_2 1121957.ATVL01000008_gene4505 7.145e-41 159.0 COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,47Q5N@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 CMS3_k127_1715999_0 382464.ABSI01000012_gene2187 2.428e-297 919.0 COG2303@1|root,COG2303@2|Bacteria,46V0V@74201|Verrucomicrobia,2IU9F@203494|Verrucomicrobiae 203494|Verrucomicrobiae E GMC oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N CMS3_k127_1715999_4 760192.Halhy_5996 1.717e-11 67.0 28KSE@1|root,2ZBRS@2|Bacteria,4NNCR@976|Bacteroidetes 976|Bacteroidetes S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_1722120_2 1123248.KB893318_gene4164 7.595e-44 162.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1IRBM@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_1722120_0 1288963.ADIS_1775 5.167e-212 668.0 COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes 976|Bacteroidetes G beta-fructofuranosidase activity - - - - - - - - - - - - - CMS3_k127_1722120_1 694427.Palpr_0722 8.25e-63 220.0 COG1670@1|root,COG1670@2|Bacteria,4NNZZ@976|Bacteroidetes 976|Bacteroidetes J (GNAT) family - - - - - - - - - - - - Acetyltransf_3 CMS3_k127_1722120_3 1046714.AMRX01000001_gene1409 2.753e-14 85.0 COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,1SY8T@1236|Gammaproteobacteria,46DI9@72275|Alteromonadaceae 1236|Gammaproteobacteria M Spermine/spermidine synthase domain - - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth CMS3_k127_1722120_4 525897.Dbac_0900 0.0002385 53.0 COG4262@1|root,COG4262@2|Bacteria,1PC06@1224|Proteobacteria,42U5M@68525|delta/epsilon subdivisions,2WQRR@28221|Deltaproteobacteria,2MGK6@213115|Desulfovibrionales 28221|Deltaproteobacteria S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth CMS3_k127_1729607_0 1120953.AUBH01000006_gene2584 3.902e-97 331.0 COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,4657Z@72275|Alteromonadaceae 1236|Gammaproteobacteria C Di-haem cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C CMS3_k127_1729607_2 1122179.KB890415_gene1994 2.19e-23 106.0 2E562@1|root,32ZYV@2|Bacteria,4NVMY@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1729607_1 485918.Cpin_1910 4.959e-33 132.0 COG3291@1|root,COG3291@2|Bacteria,4PN79@976|Bacteroidetes 976|Bacteroidetes G C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C CMS3_k127_1736363_1 1168034.FH5T_00755 3.144e-156 499.0 COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,2FP5J@200643|Bacteroidia 976|Bacteroidetes I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase CMS3_k127_1736363_0 1250232.JQNJ01000001_gene512 1.213e-293 914.0 COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,1IIHD@117743|Flavobacteriia 976|Bacteroidetes S glycosyl hydrolase of - - - ko:K09955 - - - - ko00000 - - - F5_F8_type_C,Glyco_hydro_127 CMS3_k127_1736363_2 497964.CfE428DRAFT_5426 7.428e-104 344.0 COG1680@1|root,COG1680@2|Bacteria,46WGY@74201|Verrucomicrobia 74201|Verrucomicrobia V COG1680 Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - - CMS3_k127_1742789_1 1124780.ANNU01000020_gene3319 2.228e-135 460.0 COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia 976|Bacteroidetes L Belongs to the helicase family. UvrD subfamily addA - - - - - - - - - - - Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C CMS3_k127_1742789_2 531844.FIC_00541 7.369e-22 100.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia 976|Bacteroidetes H Outer membrane receptor - - - ko:K21573 - - - - ko00000,ko02000 1.B.14.6.1 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_1742789_0 1121904.ARBP01000007_gene2998 6.825e-236 739.0 COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,47JWF@768503|Cytophagia 976|Bacteroidetes E Belongs to the alpha-IPM synthase homocitrate synthase family leuA_1 - 2.3.1.182 ko:K09011 ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230 M00535 R07399 RC00004,RC01205 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer CMS3_k127_1750597_0 1237149.C900_03215 2.075e-28 123.0 COG1595@1|root,COG1595@2|Bacteria,4PJT8@976|Bacteroidetes,47WZD@768503|Cytophagia 976|Bacteroidetes K DNA-templated transcription, initiation - - - - - - - - - - - - - CMS3_k127_1750597_1 7739.XP_002604101.1 8.632e-17 94.0 COG0457@1|root,KOG1840@2759|Eukaryota,3A00Z@33154|Opisthokonta,3BPW2@33208|Metazoa,3DDGI@33213|Bilateria 2759|Eukaryota Z Tetratricopeptide repeat - GO:0005575,GO:0005623,GO:0005929,GO:0006996,GO:0008150,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0016043,GO:0022603,GO:0022607,GO:0023051,GO:0023057,GO:0030030,GO:0030031,GO:0030111,GO:0030178,GO:0042995,GO:0043226,GO:0044085,GO:0044464,GO:0044782,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050793,GO:0050794,GO:0051239,GO:0060271,GO:0060828,GO:0065007,GO:0070925,GO:0071840,GO:0090090,GO:0090175,GO:0120025,GO:0120031,GO:0120036,GO:1905330,GO:2000026,GO:2000027,GO:2000050,GO:2000095 - ko:K10366 ko05410,ko05412,ko05414,ko05416,map05410,map05412,map05414,map05416 - - - ko00000,ko00001,ko04812 - - - DUF294,TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_1752125_0 616991.JPOO01000003_gene2355 9.722e-240 751.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1HYQE@117743|Flavobacteriia,23GHM@178469|Arenibacter 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Cytochrome_CBB3,GSDH CMS3_k127_1752125_2 391587.KAOT1_05697 5.387e-83 286.0 COG1082@1|root,COG1082@2|Bacteria,4NQV5@976|Bacteroidetes 976|Bacteroidetes G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_1752125_1 886377.Murru_2110 3.935e-140 458.0 COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1I0AT@117743|Flavobacteriia 976|Bacteroidetes I sterol desaturase - - - - - - - - - - - - FA_hydroxylase CMS3_k127_176533_5 313606.M23134_00566 0.0006343 43.0 COG0463@1|root,COG0463@2|Bacteria,4PM7X@976|Bacteroidetes,47Y12@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase, family 2 - - - - - - - - - - - - GT87 CMS3_k127_176533_3 1356852.N008_18510 2.171e-58 209.0 COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,47NJ0@768503|Cytophagia 976|Bacteroidetes S Peptidase S16, lon domain protein - - 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - LON_substr_bdg CMS3_k127_176533_4 1089547.KB913013_gene3608 2.122e-19 100.0 COG0457@1|root,COG0457@2|Bacteria,4PP15@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_176533_0 1121373.KB903625_gene3160 2.563e-135 468.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop CMS3_k127_176533_1 926549.KI421517_gene3462 7.053e-132 436.0 COG2176@1|root,COG2176@2|Bacteria,4PM8C@976|Bacteroidetes,47Y1H@768503|Cytophagia 976|Bacteroidetes L EXOIII - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - GIY-YIG,RNase_T CMS3_k127_176533_2 313606.M23134_06281 9.644e-65 234.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NSC3@976|Bacteroidetes,47S66@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,TPR_2 CMS3_k127_1769500_1 926556.Echvi_1621 8.402e-158 510.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,47NVQ@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_1769500_0 1168034.FH5T_00855 7.048e-252 791.0 COG5434@1|root,COG5434@2|Bacteria,4NG9X@976|Bacteroidetes,2FP9N@200643|Bacteroidia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - Glyco_hydro_28,Pectate_lyase_3 CMS3_k127_1769500_2 1168289.AJKI01000061_gene3369 4.777e-110 384.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,3XJSU@558415|Marinilabiliaceae 976|Bacteroidetes T helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_1772174_1 1047013.AQSP01000037_gene1323 1.047e-115 380.0 COG1171@1|root,COG1171@2|Bacteria,2NQCM@2323|unclassified Bacteria 2|Bacteria E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA tdcB - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS3_k127_1772174_0 929556.Solca_0522 3.143e-222 699.0 COG1032@1|root,COG1032@2|Bacteria,4PHMM@976|Bacteroidetes,1IWI2@117747|Sphingobacteriia 976|Bacteroidetes C radical SAM domain protein - - - - - - - - - - - - - CMS3_k127_1772174_2 761193.Runsl_1198 2.417e-114 371.0 COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,47K7S@768503|Cytophagia 976|Bacteroidetes G PFAM D-galactarate dehydratase Altronate hydrolase uxaA - 4.2.1.42,4.2.1.7 ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00631 R01540,R05608 RC00543 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C,SAF CMS3_k127_1772403_1 1168034.FH5T_20345 4.838e-12 70.0 2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1772403_0 643867.Ftrac_1364 5.851e-152 502.0 COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes,47M73@768503|Cytophagia 976|Bacteroidetes L ATP-dependent DNA helicase RecQ recQ2 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind CMS3_k127_1772403_2 1235803.C825_03949 0.0003688 44.0 COG0783@1|root,COG0783@2|Bacteria,4NQDD@976|Bacteroidetes,2FP8D@200643|Bacteroidia,22Y0J@171551|Porphyromonadaceae 976|Bacteroidetes P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin CMS3_k127_1778317_4 1321778.HMPREF1982_04318 1.041e-05 48.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,267TV@186813|unclassified Clostridiales 186801|Clostridia L helicase superfamily c-terminal domain dbpA - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C CMS3_k127_1778317_0 1121904.ARBP01000032_gene2016 3.533e-49 183.0 COG1595@1|root,COG1595@2|Bacteria,4NR8J@976|Bacteroidetes,47XM3@768503|Cytophagia 976|Bacteroidetes K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 CMS3_k127_1778317_2 760192.Halhy_0079 3.755e-24 118.0 COG2319@1|root,COG2319@2|Bacteria,4NW8I@976|Bacteroidetes 976|Bacteroidetes S Wd-40 repeat - - - - - - - - - - - - - CMS3_k127_1778317_1 760192.Halhy_0079 2.439e-27 127.0 COG2319@1|root,COG2319@2|Bacteria,4NW8I@976|Bacteroidetes 976|Bacteroidetes S Wd-40 repeat - - - - - - - - - - - - - CMS3_k127_1778317_3 929704.Myrod_1228 1.188e-13 80.0 COG0515@1|root,COG0515@2|Bacteria 929704.Myrod_1228|- KLT protein kinase activity - - - - - - - - - - - - - CMS3_k127_1778509_0 489825.LYNGBM3L_48850 3.039e-117 392.0 COG1239@1|root,COG1239@2|Bacteria,1GQHW@1117|Cyanobacteria,1HE6P@1150|Oscillatoriales 1117|Cyanobacteria H Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - - - - - - - - - - - CMS3_k127_1782477_2 109760.SPPG_04804T0 1.092e-37 144.0 COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi 4751|Fungi Q Dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS3_k127_1782477_4 1237149.C900_02814 5.867e-31 123.0 COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,47R69@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 CMS3_k127_1782477_3 886379.AEWI01000023_gene14 1.095e-33 132.0 COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,2G2BE@200643|Bacteroidia,3XK8X@558415|Marinilabiliaceae 976|Bacteroidetes J Ribosomal prokaryotic L21 protein rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - HHH_5,Rho_N,Ribosomal_L21p CMS3_k127_1782477_0 488538.SAR116_0096 7.026e-57 202.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,4BQJ2@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O SelR domain msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR CMS3_k127_1782477_1 1121957.ATVL01000011_gene3930 4.911e-48 189.0 2F9D3@1|root,341PZ@2|Bacteria,4P3ZH@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1782477_5 471854.Dfer_4063 1.489e-10 72.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia 976|Bacteroidetes S Oxygen tolerance - - - - - - - - - - - - BatD CMS3_k127_1784153_1 1499967.BAYZ01000061_gene5925 5.052e-28 117.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria 2|Bacteria S B-1 B cell differentiation - - - - - - - - - - - - GUN4,Peptidase_C14,TIR_2,WD40 CMS3_k127_1784153_2 700598.Niako_5154 9.988e-09 59.0 COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,4NP35@976|Bacteroidetes,1IVW7@117747|Sphingobacteriia 976|Bacteroidetes O COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family - - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI,YHS CMS3_k127_1784153_3 1121104.AQXH01000001_gene1756 2.305e-06 59.0 COG3206@1|root,COG3206@2|Bacteria,4NJJY@976|Bacteroidetes 976|Bacteroidetes M Chain length determinant protein - - - - - - - - - - - - GNVR,Wzz CMS3_k127_1784153_0 471854.Dfer_2769 2.673e-28 124.0 COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,47K4B@768503|Cytophagia 976|Bacteroidetes M Polysaccharide biosynthesis export protein kpsD - - - - - - - - - - - Poly_export,SLBB CMS3_k127_1794769_2 1237149.C900_01017 3.678e-34 136.0 COG2402@1|root,COG2402@2|Bacteria 2|Bacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07065 - - - - ko00000 - - - PIN,PIN_3 CMS3_k127_1794769_3 1216967.L100_09229 4.803e-19 91.0 2AMWJ@1|root,31CTC@2|Bacteria,4PBSE@976|Bacteroidetes,1IIHE@117743|Flavobacteriia,34SCB@308865|Elizabethkingia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1794769_0 1122176.KB903559_gene4141 0.0 1380.0 COG0553@1|root,COG4279@1|root,COG0553@2|Bacteria,COG4279@2|Bacteria,4NG6P@976|Bacteroidetes,1IPUE@117747|Sphingobacteriia 976|Bacteroidetes L PFAM Helicase conserved C-terminal domain - - - - - - - - - - - - DUF3670,Helicase_C,SNF2_N,SWIM CMS3_k127_1794769_1 1121904.ARBP01000006_gene3717 6.477e-207 655.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,47K4Z@768503|Cytophagia 976|Bacteroidetes E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N CMS3_k127_1795120_1 1279009.ADICEAN_01682 2.234e-74 259.0 COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,47KKI@768503|Cytophagia 976|Bacteroidetes J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT CMS3_k127_1795120_2 1550091.JROE01000002_gene1139 0.0004119 48.0 2DZQQ@1|root,32VGE@2|Bacteria,4NTQG@976|Bacteroidetes,1IUJT@117747|Sphingobacteriia 976|Bacteroidetes S Transmembrane family 220, helix - - - - - - - - - - - - TMEM220 CMS3_k127_1795120_0 761193.Runsl_5242 6.026e-105 356.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug CMS3_k127_1798975_0 1191523.MROS_0404 1.714e-139 450.0 COG3342@1|root,COG3342@2|Bacteria 2|Bacteria S Family of unknown function (DUF1028) - - - - - - - - - - - - DUF1028,TPR_16,TPR_19 CMS3_k127_1798975_1 358681.BBR47_03210 1.733e-84 289.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,26S4B@186822|Paenibacillaceae 91061|Bacilli L 8-oxoguanine DNA glycosylase alkA GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 ko:K01247,ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HhH-GPD,OGG_N CMS3_k127_1798975_3 1382358.JHVN01000038_gene3215 5.904e-37 147.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins ydaF - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 CMS3_k127_1798975_2 1385935.N836_00875 9.18e-55 203.0 COG0561@1|root,COG0561@2|Bacteria,1GDI4@1117|Cyanobacteria 1117|Cyanobacteria S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 CMS3_k127_1798975_4 1121904.ARBP01000006_gene3865 6.511e-17 84.0 COG2240@1|root,COG2240@2|Bacteria,4NNJP@976|Bacteroidetes 976|Bacteroidetes H Pyridoxal kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin CMS3_k127_1804943_4 760192.Halhy_0717 3.761e-17 81.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1IWSE@117747|Sphingobacteriia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_1804943_1 1122176.KB903539_gene1314 0.0 1124.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IPWF@117747|Sphingobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 CMS3_k127_1804943_0 1121904.ARBP01000030_gene1946 0.0 1169.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KU3@768503|Cytophagia 976|Bacteroidetes C Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 CMS3_k127_1804943_3 1123248.KB893316_gene4675 2.015e-85 284.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1IWSE@117747|Sphingobacteriia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_1804943_2 1121904.ARBP01000021_gene3616 3.344e-270 839.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 CMS3_k127_1811612_0 388413.ALPR1_18233 1.507e-161 524.0 COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,47M14@768503|Cytophagia 976|Bacteroidetes G Peptidase, M28 PGCP - - - - - - - - - - - Peptidase_M28 CMS3_k127_1811612_1 1313172.YM304_10940 4.713e-59 216.0 28SH2@1|root,2ZETH@2|Bacteria,2I3DB@201174|Actinobacteria 201174|Actinobacteria S Uncharacterized protein conserved in bacteria (DUF2236) - - - - - - - - - - - - DUF2236 CMS3_k127_1822413_0 926549.KI421517_gene2295 4.417e-193 614.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,47JAZ@768503|Cytophagia 976|Bacteroidetes O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c_3,HSP90 CMS3_k127_1822413_3 1168034.FH5T_11500 4.49e-13 83.0 COG4206@1|root,COG4206@2|Bacteria,4NI2R@976|Bacteroidetes,2FNYT@200643|Bacteroidia 976|Bacteroidetes H Psort location OuterMembrane, score - - - - - - - - - - - - Porin_10 CMS3_k127_1822413_2 714943.Mucpa_4462 1.553e-103 343.0 COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1IQGT@117747|Sphingobacteriia 976|Bacteroidetes F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1 ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 CMS3_k127_1822413_1 1121859.KB890760_gene2080 4.415e-144 464.0 COG1363@1|root,COG1363@2|Bacteria,4NIW2@976|Bacteroidetes,47JPS@768503|Cytophagia 976|Bacteroidetes G PFAM M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 CMS3_k127_1828787_2 1122176.KB903543_gene587 1.579e-68 244.0 2E10Y@1|root,32WGY@2|Bacteria,4NTDG@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1828787_3 700598.Niako_5870 9.388e-61 213.0 COG2080@1|root,COG2080@2|Bacteria,4NRVN@976|Bacteroidetes,1IY38@117747|Sphingobacteriia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.17.2.1 ko:K18029 ko00760,ko01120,map00760,map01120 M00622 R09473 RC00589 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Fer2_2 CMS3_k127_1828787_0 700598.Niako_5871 1.104e-248 790.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1IW21@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_1828787_1 760192.Halhy_2973 1.025e-196 632.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_1832205_2 485918.Cpin_4370 2.465e-13 80.0 2A7FS@1|root,30WDB@2|Bacteria,4P9TI@976|Bacteroidetes,1IZKJ@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_1832205_1 1434325.AZQN01000009_gene4067 1.463e-35 148.0 COG3712@1|root,COG3712@2|Bacteria,4NKN5@976|Bacteroidetes,47NYQ@768503|Cytophagia 976|Bacteroidetes PT Domain of unknown function (DUF4974) - - - - - - - - - - - - DUF4880,DUF4974,FecR CMS3_k127_1832205_0 411901.BACCAC_03020 1.975e-96 332.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,2FM7I@200643|Bacteroidia,4AKRS@815|Bacteroidaceae 976|Bacteroidetes P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_1835901_0 1313421.JHBV01000041_gene3559 8.977e-176 566.0 COG1960@1|root,COG1960@2|Bacteria,4NF87@976|Bacteroidetes 976|Bacteroidetes I acyl-CoA oxidase - - 1.3.3.6 ko:K00232 ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146 M00087,M00113 R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000 - - - ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_1835901_1 468059.AUHA01000002_gene224 6.179e-94 319.0 COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1IRI6@117747|Sphingobacteriia 976|Bacteroidetes P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 CMS3_k127_1835901_3 1229276.DI53_1405 6.487e-55 204.0 COG1597@1|root,COG1597@2|Bacteria,4NJWB@976|Bacteroidetes,1IQ8Q@117747|Sphingobacteriia 976|Bacteroidetes I Diacylglycerol kinase - - - - - - - - - - - - DAGK_cat CMS3_k127_1835901_2 1313421.JHBV01000042_gene3251 4.148e-93 328.0 COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia 976|Bacteroidetes M OmpA MotB domain protein - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA CMS3_k127_1835901_5 1227739.Hsw_3217 1.329e-17 87.0 COG1539@1|root,COG1539@2|Bacteria,4NQ53@976|Bacteroidetes,47QM5@768503|Cytophagia 976|Bacteroidetes H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB CMS3_k127_1835901_4 153721.MYP_1368 6.709e-55 201.0 COG1624@1|root,COG1624@2|Bacteria,4NG3Z@976|Bacteroidetes,47JT6@768503|Cytophagia 976|Bacteroidetes S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - - - - - - - - - - - DisA_N CMS3_k127_1840880_0 756272.Plabr_4157 3.354e-250 784.0 COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - - - - - - - - - - - Sulfatase CMS3_k127_1840880_1 1121904.ARBP01000007_gene3111 2.137e-06 51.0 COG2319@1|root,COG2319@2|Bacteria,4PP7D@976|Bacteroidetes,47WB4@768503|Cytophagia 976|Bacteroidetes S TIR domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - TIR_2 CMS3_k127_184569_7 1122179.KB890436_gene1408 0.0001769 49.0 2E8Y2@1|root,3337T@2|Bacteria,4NUTB@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_184569_4 745718.JADT01000009_gene3019 3.172e-23 112.0 2F6AM@1|root,33YUA@2|Bacteria,4P3YF@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - SH3_3 CMS3_k127_184569_5 745718.JADT01000009_gene3019 5.904e-12 77.0 2F6AM@1|root,33YUA@2|Bacteria,4P3YF@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - SH3_3 CMS3_k127_184569_2 547042.BACCOPRO_02577 6.712e-74 265.0 COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,2FN49@200643|Bacteroidia,4AMYG@815|Bacteroidaceae 976|Bacteroidetes S Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_184569_0 1279009.ADICEAN_03872 2.409e-139 457.0 COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47JGY@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_184569_6 743722.Sph21_1080 4.586e-08 59.0 2AVJD@1|root,31MC1@2|Bacteria,4NQQQ@976|Bacteroidetes,1ISQZ@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_184569_1 1313301.AUGC01000001_gene1404 5.139e-136 440.0 COG0536@1|root,COG0536@2|Bacteria,4NEK4@976|Bacteroidetes 976|Bacteroidetes S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 CMS3_k127_184569_3 743722.Sph21_0074 5.382e-62 218.0 COG0563@1|root,COG0563@2|Bacteria,4NG7J@976|Bacteroidetes,1IRJW@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,Pribosyltran CMS3_k127_1847088_0 1121904.ARBP01000006_gene3720 1.289e-194 617.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,47MZ0@768503|Cytophagia 976|Bacteroidetes E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC CMS3_k127_1847088_1 760192.Halhy_4647 2.818e-190 601.0 COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,1INZR@117747|Sphingobacteriia 976|Bacteroidetes E Cleaves the N-terminal amino acid of tripeptides pepT - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_1847088_2 700598.Niako_5065 2.633e-13 70.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,1INX4@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase CMS3_k127_1847372_0 1120973.AQXL01000135_gene1433 1.041e-243 761.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,278ZG@186823|Alicyclobacillaceae 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK - 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N CMS3_k127_1847372_7 1237149.C900_03216 1.201e-11 74.0 COG0457@1|root,COG0457@2|Bacteria,4PPNU@976|Bacteroidetes,47YQH@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_1847372_8 491205.JARQ01000004_gene2358 6.444e-09 66.0 COG1595@1|root,COG1595@2|Bacteria,4NQJE@976|Bacteroidetes,1IJ12@117743|Flavobacteriia,3ZTAJ@59732|Chryseobacterium 976|Bacteroidetes K RNA polymerase - - - - - - - - - - - - Sigma70_r2 CMS3_k127_1847372_6 1121904.ARBP01000008_gene3274 7.006e-47 178.0 28NZH@1|root,2ZBWE@2|Bacteria,4NM7N@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1847372_1 1288963.ADIS_2559 3.759e-110 361.0 COG5285@1|root,COG5285@2|Bacteria,4NFFH@976|Bacteroidetes,47NG3@768503|Cytophagia 976|Bacteroidetes Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH CMS3_k127_1847372_2 1313421.JHBV01000015_gene5788 4.27e-86 301.0 COG2373@1|root,COG2373@2|Bacteria,4P17V@976|Bacteroidetes 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - - CMS3_k127_1847372_3 313595.P700755_003529 4.983e-71 247.0 28JH1@1|root,2Z9AM@2|Bacteria,4NJYJ@976|Bacteroidetes,1I0ZC@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1847372_4 1122176.KB903531_gene2954 6.472e-64 233.0 COG1657@1|root,COG1657@2|Bacteria 2|Bacteria I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - DUF4430,PrcB_C,Prenyltrans,SLH,SQHop_cyclase_C CMS3_k127_1847864_1 715451.ambt_14330 1.066e-05 55.0 COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,1S5DM@1236|Gammaproteobacteria,468JA@72275|Alteromonadaceae 1236|Gammaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_184904_4 742766.HMPREF9455_03488 1.482e-05 52.0 COG1403@1|root,COG1403@2|Bacteria,4NPED@976|Bacteroidetes 976|Bacteroidetes V HNH nucleases - - - - - - - - - - - - HNH CMS3_k127_184904_0 760192.Halhy_5493 9.822e-55 197.0 2F17F@1|root,33U8J@2|Bacteria,4P2WT@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_184904_1 1122176.KB903554_gene3913 3.589e-20 107.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_184904_3 1069080.KB913028_gene524 1.162e-05 59.0 COG0457@1|root,COG0457@2|Bacteria,1U4DH@1239|Firmicutes,4H5FH@909932|Negativicutes 909932|Negativicutes S PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - - - - - - - - - - TPR_1,TPR_2,TPR_8 CMS3_k127_184904_2 929703.KE386491_gene2384 6.474e-20 93.0 COG0607@1|root,COG0607@2|Bacteria,4NUPH@976|Bacteroidetes,47RS4@768503|Cytophagia 976|Bacteroidetes P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese CMS3_k127_1860234_9 1237149.C900_02643 0.0001006 46.0 2BVQD@1|root,332WQ@2|Bacteria,4NXE1@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1860234_7 485918.Cpin_5460 2.673e-24 109.0 28P9K@1|root,2ZC31@2|Bacteria,4NPW6@976|Bacteroidetes,1IYXR@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 CMS3_k127_1860234_3 643867.Ftrac_1377 1.908e-93 315.0 COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,47Q1V@768503|Cytophagia 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_1860234_5 1237149.C900_02649 1.812e-46 177.0 COG1277@1|root,COG1277@2|Bacteria,4NEES@976|Bacteroidetes,47WZW@768503|Cytophagia 976|Bacteroidetes S Excinuclease ABC subunit B - - - - - - - - - - - - ABC2_membrane_2,ABC2_membrane_4 CMS3_k127_1860234_1 1380384.JADN01000007_gene1546 7.673e-121 392.0 COG0330@1|root,COG0330@2|Bacteria,4NFPK@976|Bacteroidetes,1HZJ2@117743|Flavobacteriia 976|Bacteroidetes O prohibitin homologues - - - - - - - - - - - - Band_7 CMS3_k127_1860234_2 926559.JoomaDRAFT_2107 2.289e-112 369.0 COG1718@1|root,COG1718@2|Bacteria,4NEF6@976|Bacteroidetes,1HXTI@117743|Flavobacteriia 976|Bacteroidetes DT aminotransferase class I and II - - - - - - - - - - - - - CMS3_k127_1860234_6 1123278.KB893604_gene1937 2.478e-38 147.0 2CP0Z@1|root,32SI8@2|Bacteria,4NQDB@976|Bacteroidetes,47QAP@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF3037) - - - - - - - - - - - - DUF3037 CMS3_k127_1860234_4 926549.KI421517_gene3152 1.562e-71 259.0 COG3250@1|root,COG3250@2|Bacteria,4NHRV@976|Bacteroidetes,47JP4@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolases family 2, TIM barrel domain - - - - - - - - - - - - Glyco_hydro_2_C CMS3_k127_1860234_0 1239962.C943_01358 1.213e-225 735.0 COG1215@1|root,COG3250@1|root,COG4124@1|root,COG1215@2|Bacteria,COG3250@2|Bacteria,COG4124@2|Bacteria,4NEK9@976|Bacteroidetes,47KAY@768503|Cytophagia 976|Bacteroidetes M Cellulose synthase - - 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - Glyco_hydro_26,Glyco_hydro_2_C,Glyco_transf_21 CMS3_k127_1884107_1 1346330.M472_13695 3.061e-52 187.0 COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,1INQT@117747|Sphingobacteriia 976|Bacteroidetes S GlcNAc-PI de-N-acetylase bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L CMS3_k127_1884107_2 755732.Fluta_2097 7.183e-49 197.0 28M1N@1|root,2ZAGE@2|Bacteria,4NIDD@976|Bacteroidetes,1I8D6@117743|Flavobacteriia,2PARN@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_1884107_0 313606.M23134_07921 9.642e-72 256.0 COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,47JDH@768503|Cytophagia 976|Bacteroidetes M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 CMS3_k127_1885832_1 700598.Niako_4480 1.309e-57 229.0 COG3291@1|root,COG3291@2|Bacteria,4NPDM@976|Bacteroidetes,1IW61@117747|Sphingobacteriia 976|Bacteroidetes G PFAM PKD domain - - - - - - - - - - - - CHU_C,PKD CMS3_k127_1885832_3 929556.Solca_0544 0.0002876 48.0 COG0708@1|root,COG0708@2|Bacteria 2|Bacteria L double-stranded DNA 3'-5' exodeoxyribonuclease activity - - - - - - - - - - - - Exo_endo_phos CMS3_k127_1885832_0 880071.Fleli_1838 4.541e-85 297.0 COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,47NJH@768503|Cytophagia 976|Bacteroidetes I Domain of unknown function (DUF389) - - - - - - - - - - - - DUF389 CMS3_k127_1895163_2 756272.Plabr_1304 9.399e-18 90.0 2E3N5@1|root,32YKB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_1895163_0 118168.MC7420_7338 4.166e-68 241.0 2DTTJ@1|root,32UVW@2|Bacteria,1G8TS@1117|Cyanobacteria,1HCTF@1150|Oscillatoriales 1117|Cyanobacteria S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 CMS3_k127_1895163_1 1304885.AUEY01000015_gene2977 6.855e-29 125.0 COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,42N14@68525|delta/epsilon subdivisions,2WIKT@28221|Deltaproteobacteria,2MIBP@213118|Desulfobacterales 28221|Deltaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_189580_3 1227739.Hsw_3171 1.679e-66 241.0 COG2885@1|root,COG2885@2|Bacteria,4NHWF@976|Bacteroidetes,47MMG@768503|Cytophagia 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_189580_5 1280692.AUJL01000001_gene65 1.297e-13 78.0 COG1437@1|root,COG1437@2|Bacteria,1V9MR@1239|Firmicutes,24GAC@186801|Clostridia,36I5U@31979|Clostridiaceae 186801|Clostridia F Adenylate cyclase - - 4.6.1.1 ko:K05873 ko00230,map00230 - R00089,R00434 RC00295 ko00000,ko00001,ko01000 - - - CYTH CMS3_k127_189580_4 880073.Calab_1648 8.273e-42 158.0 COG4731@1|root,COG4731@2|Bacteria 2|Bacteria S Uncharacterized protein conserved in bacteria (DUF2147) - - - - - - - - - - - - DUF2147 CMS3_k127_189580_2 485917.Phep_4158 1.003e-109 361.0 COG1809@1|root,COG1809@2|Bacteria,4NEHT@976|Bacteroidetes,1IPYS@117747|Sphingobacteriia 976|Bacteroidetes S PFAM (2R)-phospho-3-sulfolactate synthase ComA - - 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 - - - ComA CMS3_k127_189580_1 1107311.Q767_12015 3.916e-117 393.0 COG2355@1|root,COG2355@2|Bacteria,4NI3V@976|Bacteroidetes,1I0XS@117743|Flavobacteriia 976|Bacteroidetes E Zn-dependent dipeptidase, microsomal dipeptidase - - - - - - - - - - - - Peptidase_M19 CMS3_k127_189580_0 926549.KI421517_gene1008 1.535e-218 703.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug CMS3_k127_192408_2 1408813.AYMG01000011_gene818 2.531e-138 447.0 COG1066@1|root,COG1066@2|Bacteria,4NEYA@976|Bacteroidetes,1IQC6@117747|Sphingobacteriia 976|Bacteroidetes O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI CMS3_k127_192408_5 179408.Osc7112_0323 2.125e-32 141.0 COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HASA@1150|Oscillatoriales 1117|Cyanobacteria S KWG Leptospira - - - - - - - - - - - - SLH,WG_beta_rep CMS3_k127_192408_1 880071.Fleli_3863 6.186e-175 559.0 COG0192@1|root,COG0192@2|Bacteria,4NG7Y@976|Bacteroidetes,47JW7@768503|Cytophagia 976|Bacteroidetes H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N CMS3_k127_192408_4 1237149.C900_03416 4.41e-45 173.0 COG0220@1|root,COG0220@2|Bacteria,4NG4V@976|Bacteroidetes,47JY6@768503|Cytophagia 976|Bacteroidetes J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 CMS3_k127_192408_0 929556.Solca_1437 0.0 1132.0 COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1IQJH@117747|Sphingobacteriia 976|Bacteroidetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV CMS3_k127_192408_6 929556.Solca_1438 1.041e-18 99.0 COG0457@1|root,COG0457@2|Bacteria,4NFHT@976|Bacteroidetes,1IRZE@117747|Sphingobacteriia 976|Bacteroidetes S tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_17,TPR_19,TPR_2,TPR_8 CMS3_k127_192408_3 1124780.ANNU01000073_gene722 7.493e-79 276.0 2DBCF@1|root,2Z8DB@2|Bacteria,4NG6B@976|Bacteroidetes,47JNN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Caps_assemb_Wzi CMS3_k127_1924793_5 1120965.AUBV01000001_gene3441 1.968e-07 55.0 COG0337@1|root,COG0337@2|Bacteria,4NGSS@976|Bacteroidetes,47JBE@768503|Cytophagia 976|Bacteroidetes E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase CMS3_k127_1924793_0 929556.Solca_1259 9.962e-182 597.0 COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,4NEXM@976|Bacteroidetes,1IP9R@117747|Sphingobacteriia 976|Bacteroidetes M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,6.3.2.10 ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 - R00401,R04573,R04617 RC00064,RC00141,RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_M CMS3_k127_1924793_1 1279009.ADICEAN_01935 1.692e-102 348.0 COG1262@1|root,COG1262@2|Bacteria,4NE51@976|Bacteroidetes,47JSB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated lipoprotein GldJ gldJ - - - - - - - - - - - FGE-sulfatase CMS3_k127_1924793_4 1121481.AUAS01000014_gene2340 7.954e-59 218.0 COG4772@1|root,COG4772@2|Bacteria,4NG13@976|Bacteroidetes,47MUX@768503|Cytophagia 976|Bacteroidetes P TIGRFAM Bacteroidetes-specific - - - - - - - - - - - - PorP_SprF CMS3_k127_1924793_2 1237149.C900_04331 2.767e-80 273.0 COG1760@1|root,COG1760@2|Bacteria,4NFXU@976|Bacteroidetes,47NN2@768503|Cytophagia 976|Bacteroidetes E Serine dehydratase - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_beta CMS3_k127_1924793_3 1168034.FH5T_10710 4.72e-79 281.0 COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,2FM98@200643|Bacteroidia 976|Bacteroidetes MU Outer membrane efflux protein - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP CMS3_k127_1934101_1 1270196.JCKI01000010_gene861 1.064e-59 215.0 COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1IQU2@117747|Sphingobacteriia 976|Bacteroidetes H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M CMS3_k127_1934101_0 1237149.C900_03990 9.629e-213 669.0 COG0017@1|root,COG0017@2|Bacteria,4NDY4@976|Bacteroidetes,47JG8@768503|Cytophagia 976|Bacteroidetes J Asparaginyl-tRNA synthetase asnS - 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon CMS3_k127_1934101_4 1121896.JMLU01000003_gene2156 1.493e-13 74.0 COG2919@1|root,COG2919@2|Bacteria,4NURQ@976|Bacteroidetes,1I5AD@117743|Flavobacteriia,2NX26@237|Flavobacterium 976|Bacteroidetes D Septum formation initiator - - - - - - - - - - - - DivIC CMS3_k127_1934101_2 242159.ABO98054 6.34e-54 203.0 COG4642@1|root,KOG0231@2759|Eukaryota,37J9P@33090|Viridiplantae,34P5U@3041|Chlorophyta 3041|Chlorophyta T Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - - - - - - - - - - MORN CMS3_k127_1934101_3 1122179.KB890441_gene1069 8.158e-45 170.0 COG3291@1|root,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,1IR9W@117747|Sphingobacteriia 976|Bacteroidetes U PFAM PKD domain - - - - - - - - - - - - CHU_C,IgGFc_binding,PKD,SprB CMS3_k127_1949138_0 1122179.KB890491_gene4478 2.278e-80 276.0 COG5295@1|root,COG5295@2|Bacteria,4NMJW@976|Bacteroidetes 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - DUF1566,Peptidase_S74 CMS3_k127_1949138_3 1166018.FAES_1189 7.214e-26 113.0 COG0839@1|root,COG0839@2|Bacteria,4NNMC@976|Bacteroidetes,47PS1@768503|Cytophagia 976|Bacteroidetes C PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 nuoJ - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 CMS3_k127_1949138_4 1313421.JHBV01000016_gene5462 1.17e-19 106.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - BSP,CHU_C,PKD,SprB CMS3_k127_1949138_2 906888.JCM19314_1987 2.18e-60 240.0 COG3291@1|root,COG3291@2|Bacteria,4PHVK@976|Bacteroidetes,1IDN4@117743|Flavobacteriia,3HJ5A@363408|Nonlabens 976|Bacteroidetes O Fibronectin type III domain - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - MAM,fn3 CMS3_k127_1949138_1 1122176.KB903542_gene336 9.103e-76 259.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes 976|Bacteroidetes E Glutamate formimidoyltransferase ftcD - 2.1.2.5,4.3.1.4 ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 - R02287,R02302,R03189 RC00165,RC00221,RC00223,RC00688,RC00870 ko00000,ko00001,ko01000,ko03036,ko04147 - - - FTCD,FTCD_C,FTCD_N CMS3_k127_1972240_3 1122176.KB903541_gene183 4.106e-43 161.0 COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1IWAN@117747|Sphingobacteriia 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_1972240_2 1185876.BN8_01495 1.589e-109 359.0 COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,47MY4@768503|Cytophagia 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_1972240_0 1453498.LG45_05070 9.24e-131 427.0 COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes,1HX8Q@117743|Flavobacteriia,2NT6W@237|Flavobacterium 976|Bacteroidetes U ABC-2 type transporter ybhS - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS3_k127_1972240_1 1121012.AUKX01000039_gene3169 2.605e-121 400.0 COG0842@1|root,COG0842@2|Bacteria,4NFM0@976|Bacteroidetes,1HYPJ@117743|Flavobacteriia,23G0C@178469|Arenibacter 976|Bacteroidetes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS3_k127_1972240_4 163908.KB235896_gene4328 7.728e-30 126.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1,Glycos_transf_2 CMS3_k127_1972240_5 4929.XP_001483512.1 7.931e-16 88.0 COG0484@1|root,KOG0712@2759|Eukaryota,38GG3@33154|Opisthokonta,3NU15@4751|Fungi,3QJJ1@4890|Ascomycota,3RTBA@4891|Saccharomycetes,47C7D@766764|Debaryomycetaceae 4751|Fungi O DnaJ central domain SCJ1 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006986,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0019538,GO:0019941,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031974,GO:0033554,GO:0034620,GO:0034975,GO:0034976,GO:0035966,GO:0035967,GO:0036503,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051087,GO:0051603,GO:0051716,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901698 - ko:K14002 ko04141,map04141 - - - ko00000,ko00001 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CMS3_k127_1972240_6 1209989.TepiRe1_1198 0.0004604 43.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,42ESV@68295|Thermoanaerobacterales 186801|Clostridia O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CMS3_k127_1975927_3 385682.AFSL01000016_gene2016 2.27e-75 256.0 COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,2FMNU@200643|Bacteroidia,3XIKS@558415|Marinilabiliaceae 976|Bacteroidetes T Elongation factor G C-terminus typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 CMS3_k127_1975927_1 1122176.KB903547_gene1125 3.152e-128 417.0 COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,1INM8@117747|Sphingobacteriia 976|Bacteroidetes F Phosphoribosylaminoimidazolesuccinocarboxamide synthase purC GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt CMS3_k127_1975927_0 1121930.AQXG01000007_gene538 1.541e-192 619.0 COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1IPI4@117747|Sphingobacteriia 976|Bacteroidetes S ABC transporter yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CMS3_k127_1975927_2 1124780.ANNU01000061_gene910 1.032e-81 281.0 COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,47P83@768503|Cytophagia 976|Bacteroidetes S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563,ko:K22318 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS3_k127_1978367_0 1358423.N180_04990 6.012e-227 725.0 COG0457@1|root,COG0457@2|Bacteria,4NZVB@976|Bacteroidetes,1IVUF@117747|Sphingobacteriia 976|Bacteroidetes S Tetratricopeptide repeats - - - - - - - - - - - - TPR_16 CMS3_k127_1978367_1 153721.MYP_1808 3.047e-173 550.0 COG4867@1|root,COG4867@2|Bacteria,4NFMA@976|Bacteroidetes,47K13@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - - - - - - - - - - VWA_2 CMS3_k127_1978367_2 485917.Phep_1887 3.379e-11 71.0 COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,1INZN@117747|Sphingobacteriia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_1983073_0 999419.HMPREF1077_03288 3.881e-140 452.0 COG1277@1|root,COG1277@2|Bacteria,4NGAT@976|Bacteroidetes,2FP5B@200643|Bacteroidia,22WDU@171551|Porphyromonadaceae 976|Bacteroidetes S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 CMS3_k127_1983073_2 1121129.KB903372_gene398 6.624e-98 329.0 COG1131@1|root,COG1131@2|Bacteria,4NFNM@976|Bacteroidetes,2FM6N@200643|Bacteroidia,22WPT@171551|Porphyromonadaceae 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system yxlF_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_1983073_1 1122931.AUAE01000010_gene4440 1.617e-121 402.0 COG1470@1|root,COG1470@2|Bacteria,4NHIX@976|Bacteroidetes,2FN9I@200643|Bacteroidia,22WAR@171551|Porphyromonadaceae 976|Bacteroidetes S NPCBM-associated, NEW3 domain of alpha-galactosidase - - - - - - - - - - - - NPCBM_assoc CMS3_k127_1983073_3 471854.Dfer_5074 2.365e-20 94.0 COG1752@1|root,COG1752@2|Bacteria,4PN3T@976|Bacteroidetes,47KSP@768503|Cytophagia 976|Bacteroidetes S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin CMS3_k127_1998819_0 1313301.AUGC01000020_gene711 3.781e-166 532.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes 976|Bacteroidetes J seryl-tRNA synthetase serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b CMS3_k127_1998819_1 1185876.BN8_04869 2.653e-155 499.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,47K8V@768503|Cytophagia 976|Bacteroidetes G Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK CMS3_k127_1998819_2 1121904.ARBP01000002_gene6689 2.122e-17 86.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes 2|Bacteria K COG0457 FOG TPR repeat - - - - - - - - - - - - CHAT,TPR_12,TPR_16,TPR_7,TPR_8 CMS3_k127_2007295_5 1121904.ARBP01000010_gene2354 1.912e-169 540.0 COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia 976|Bacteroidetes E PFAM Membrane dipeptidase (Peptidase family M19) - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 CMS3_k127_2007295_4 1121904.ARBP01000004_gene799 1.773e-174 559.0 COG3211@1|root,COG3211@2|Bacteria,4NKFU@976|Bacteroidetes,47P4I@768503|Cytophagia 976|Bacteroidetes S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 CMS3_k127_2007295_0 1121011.AUCB01000008_gene1224 0.0 1071.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,23FKS@178469|Arenibacter 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_2007295_9 391603.FBALC1_12572 4.081e-62 221.0 COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,1I1PS@117743|Flavobacteriia 976|Bacteroidetes MUW Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74,YadA_head CMS3_k127_2007295_6 760192.Halhy_1164 3.91e-154 502.0 COG2234@1|root,COG2234@2|Bacteria,4NEHY@976|Bacteroidetes 976|Bacteroidetes S Peptidase m28 - - - - - - - - - - - - PA,Peptidase_M28 CMS3_k127_2007295_3 1121904.ARBP01000007_gene3098 8.264e-193 610.0 COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,47JCJ@768503|Cytophagia 976|Bacteroidetes E PFAM Sodium alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp CMS3_k127_2007295_11 643867.Ftrac_3224 9.358e-37 149.0 COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47W07@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CMS3_k127_2007295_10 643867.Ftrac_3224 1.666e-43 168.0 COG0204@1|root,COG0204@2|Bacteria,4NG5R@976|Bacteroidetes,47W07@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CMS3_k127_2007295_2 1089547.KB913013_gene2149 2.999e-197 622.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,47MI4@768503|Cytophagia 976|Bacteroidetes G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N CMS3_k127_2007295_7 1189612.A33Q_3807 5.221e-79 273.0 COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,47JPF@768503|Cytophagia 976|Bacteroidetes S PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yafV - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase CMS3_k127_2007295_16 929713.NIASO_20140 0.000877 44.0 COG0554@1|root,COG0554@2|Bacteria,4NF9T@976|Bacteroidetes,1IQVB@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the FGGY kinase family - - 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N CMS3_k127_2007295_1 313596.RB2501_13119 5.56e-224 704.0 COG1231@1|root,COG1231@2|Bacteria,4PMAQ@976|Bacteroidetes,1IMSK@117743|Flavobacteriia 976|Bacteroidetes E Protein of unknown function (DUF1593) - - - - - - - - - - - - DUF1593 CMS3_k127_2007295_15 1408254.T458_20435 3.314e-15 86.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,26QMV@186822|Paenibacillaceae 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CMS3_k127_2007295_12 1121904.ARBP01000018_gene2610 1.259e-22 102.0 COG3937@1|root,COG3937@2|Bacteria,4NUSK@976|Bacteroidetes,47SH5@768503|Cytophagia 976|Bacteroidetes S granule-associated protein - - - - - - - - - - - - - CMS3_k127_2007295_8 1117379.BABA_18846 3.133e-66 233.0 COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus 91061|Bacilli I COG0657 Esterase lipase - - - ko:K01066 - - - - ko00000,ko01000 - - - Abhydrolase_3 CMS3_k127_2014584_2 929562.Emtol_0932 5.362e-62 220.0 COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,47MAC@768503|Cytophagia 976|Bacteroidetes L single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS3_k127_2014584_6 247490.KSU1_C0730 1.661e-25 124.0 COG2234@1|root,COG3291@1|root,COG3420@1|root,COG4409@1|root,COG5184@1|root,COG5276@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4409@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria 2|Bacteria DZ guanyl-nucleotide exchange factor activity iap GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 ko:K01179,ko:K03929,ko:K09612,ko:K12287,ko:K19701,ko:K19702 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000,ko01002,ko02044 - CE10,GH5,GH9 - Beta_helix,Peptidase_M28 CMS3_k127_2014584_1 867902.Ornrh_1824 2.386e-97 323.0 COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1HX61@117743|Flavobacteriia 976|Bacteroidetes S ABC transporter lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C CMS3_k127_2014584_0 1237149.C900_04542 8.949e-200 634.0 COG0318@1|root,COG0318@2|Bacteria,4PKJY@976|Bacteroidetes,47KAH@768503|Cytophagia 976|Bacteroidetes IQ PFAM GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 CMS3_k127_2014584_3 743722.Sph21_1368 8.064e-60 214.0 COG0688@1|root,COG0688@2|Bacteria,4NFU1@976|Bacteroidetes,1INZC@117747|Sphingobacteriia 976|Bacteroidetes I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase CMS3_k127_2014584_4 1089547.KB913013_gene2096 9.945e-54 192.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,47PQ6@768503|Cytophagia 976|Bacteroidetes E PFAM Glyoxalase bleomycin resistance protein dioxygenase mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 CMS3_k127_2014584_5 1121129.KB903359_gene2181 6.024e-52 202.0 COG1596@1|root,COG1596@2|Bacteria,4NEXJ@976|Bacteroidetes,2FM4E@200643|Bacteroidia,22WXT@171551|Porphyromonadaceae 976|Bacteroidetes M Polysaccharide biosynthesis/export protein kpsD - - - - - - - - - - - Caps_synth_GfcC,Poly_export,SLBB CMS3_k127_2040203_5 1121904.ARBP01000031_gene555 8.011e-11 62.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47NVQ@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_2040203_2 926556.Echvi_1622 2.241e-170 548.0 COG0446@1|root,COG0446@2|Bacteria,4PNU3@976|Bacteroidetes 976|Bacteroidetes S PFAM SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_2040203_4 1453505.JASY01000001_gene3467 1.281e-46 169.0 COG3254@1|root,COG3254@2|Bacteria,4NSEM@976|Bacteroidetes,1I4MI@117743|Flavobacteriia,2NWX6@237|Flavobacterium 976|Bacteroidetes G Involved in the anomeric conversion of L-rhamnose - - 5.1.3.32 ko:K03534 - - R10819 RC00563 ko00000,ko01000 - - - rhaM CMS3_k127_2040203_1 1123276.KB893245_gene1727 1.867e-263 821.0 COG3664@1|root,COG3664@2|Bacteria,4NHQ0@976|Bacteroidetes,47N7Z@768503|Cytophagia 976|Bacteroidetes G PFAM glycoside hydrolase family 39 - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_39 CMS3_k127_2040203_3 1121957.ATVL01000012_gene852 3.182e-154 497.0 COG0823@1|root,COG0823@2|Bacteria,4NJJ5@976|Bacteroidetes 976|Bacteroidetes U Oligogalacturonate lyase - - 4.2.2.6 ko:K01730 ko00040,map00040 - R04382 RC02124,RC02427 ko00000,ko00001,ko01000 - - - Pectate_lyase22 CMS3_k127_2040203_0 926559.JoomaDRAFT_2298 0.0 1127.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,4NEM0@976|Bacteroidetes,1HXU6@117743|Flavobacteriia 976|Bacteroidetes IQ short-chain dehydrogenase - - - - - - - - - - - - Aldolase_II,adh_short,adh_short_C2 CMS3_k127_2043115_2 760192.Halhy_0310 0.0001224 52.0 COG0642@1|root,COG2205@2|Bacteria,4NI8C@976|Bacteroidetes,1IWXD@117747|Sphingobacteriia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_2043115_1 1408433.JHXV01000022_gene3151 8.641e-32 134.0 28J3Q@1|root,32BQT@2|Bacteria,4PJ56@976|Bacteroidetes,1IFVN@117743|Flavobacteriia,2PC57@246874|Cryomorphaceae 976|Bacteroidetes S Protein of unknown function (Porph_ging) - - - - - - - - - - - - Porph_ging CMS3_k127_2043115_0 761193.Runsl_2121 5.564e-140 466.0 COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 CMS3_k127_2051245_2 448385.sce1370 6.757e-61 215.0 COG0262@1|root,COG0262@2|Bacteria,1PXAB@1224|Proteobacteria,43DS4@68525|delta/epsilon subdivisions,2WYRF@28221|Deltaproteobacteria,2Z0F8@29|Myxococcales 28221|Deltaproteobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C CMS3_k127_2051245_0 313603.FB2170_15673 5.852e-186 592.0 COG3119@1|root,COG3119@2|Bacteria,4NEDH@976|Bacteroidetes,1I0X0@117743|Flavobacteriia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_2051245_1 616991.JPOO01000001_gene4353 8.964e-176 559.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia,23GZ2@178469|Arenibacter 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_2084980_4 1408473.JHXO01000007_gene947 1.061e-19 90.0 COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,2FNXT@200643|Bacteroidia 976|Bacteroidetes S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_2084980_1 1313301.AUGC01000005_gene283 2.178e-103 341.0 COG0302@1|root,COG0302@2|Bacteria,4NFC2@976|Bacteroidetes 976|Bacteroidetes H gtp cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI CMS3_k127_2084980_3 1239962.C943_02757 6.236e-63 218.0 COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,47PQ5@768503|Cytophagia 976|Bacteroidetes H PFAM 6-pyruvoyl tetrahydropterin synthase ygcM - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS CMS3_k127_2084980_0 1121904.ARBP01000005_gene4664 2.482e-169 545.0 COG1233@1|root,COG1233@2|Bacteria,4NHU6@976|Bacteroidetes,47S0F@768503|Cytophagia 976|Bacteroidetes Q Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_1 CMS3_k127_2084980_2 1123508.JH636445_gene6760 7.364e-67 232.0 COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.8 ko:K01134 ko00600,ko04142,map00600,map04142 - R04856 RC00231 ko00000,ko00001,ko01000 - - - Sulfatase CMS3_k127_2094297_2 498211.CJA_0343 2.843e-23 117.0 COG1520@1|root,COG3209@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - Calx-beta,DUF1566,DUF4114,DUF4347,FG-GAP,HemolysinCabind,PQQ_3,RHS,RHS_repeat,SLH CMS3_k127_2094297_0 1408473.JHXO01000001_gene2252 1.556e-79 297.0 COG1404@1|root,COG3209@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,4NTHZ@976|Bacteroidetes,2FY64@200643|Bacteroidia 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_2094297_1 1123248.KB893314_gene3504 5.479e-27 128.0 2DTCS@1|root,33JR4@2|Bacteria,4PPRB@976|Bacteroidetes,1J11U@117747|Sphingobacteriia 2|Bacteria S Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74 CMS3_k127_2095143_5 391598.FBBAL38_08485 3.193e-10 64.0 COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,1HZIN@117743|Flavobacteriia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_2095143_4 983548.Krodi_0464 2.98e-26 121.0 COG3568@1|root,COG3568@2|Bacteria,4NGUV@976|Bacteroidetes,1IJJS@117743|Flavobacteriia,37DYZ@326319|Dokdonia 976|Bacteroidetes S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos CMS3_k127_2095143_0 1501391.LG35_08985 9.508e-181 579.0 COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,2FM9D@200643|Bacteroidia,22U1I@171550|Rikenellaceae 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e CMS3_k127_2095143_1 385682.AFSL01000068_gene1442 2.591e-90 308.0 COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,2FN1C@200643|Bacteroidia,3XJHQ@558415|Marinilabiliaceae 976|Bacteroidetes S Peptidase family M28 ywaD - - - - - - - - - - - Peptidase_M28 CMS3_k127_2095143_3 1122621.ATZA01000033_gene487 2.089e-55 207.0 COG1215@1|root,COG1215@2|Bacteria,4NESG@976|Bacteroidetes,1IQGQ@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_2095143_2 153721.MYP_1315 4.056e-61 216.0 COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,47JCE@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_2095143_6 1250006.JHZZ01000001_gene2863 8.35e-07 50.0 COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,3VVK2@52959|Polaribacter 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_2129201_2 984262.SGRA_1984 1.822e-80 284.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1IXFQ@117747|Sphingobacteriia 976|Bacteroidetes K COG0457 FOG TPR repeat - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_8 CMS3_k127_2129201_0 1121904.ARBP01000026_gene694 1.208e-195 616.0 COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,47MAS@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_2129201_1 1121904.ARBP01000010_gene2234 4.782e-125 412.0 COG0477@1|root,COG2814@2|Bacteria,4PKJD@976|Bacteroidetes,47M36@768503|Cytophagia 976|Bacteroidetes EGP PFAM nucleoside H symporter - - - - - - - - - - - - Nuc_H_symport CMS3_k127_2138548_1 1166018.FAES_1173 3.221e-104 347.0 COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia 976|Bacteroidetes S Rhodanese Homology Domain - - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese CMS3_k127_2138548_0 929556.Solca_3437 1.435e-133 436.0 COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1IR5V@117747|Sphingobacteriia 976|Bacteroidetes S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 CMS3_k127_2138548_3 1121904.ARBP01000003_gene6215 1.385e-66 230.0 28NIX@1|root,2ZBK6@2|Bacteria,4NMEI@976|Bacteroidetes,47MBS@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2480) - - - - - - - - - - - - DUF2480 CMS3_k127_2138548_2 1185876.BN8_02849 7.396e-102 342.0 COG4260@1|root,COG4260@2|Bacteria,4NHXG@976|Bacteroidetes,47TDD@768503|Cytophagia 976|Bacteroidetes S virion core protein (lumpy skin disease virus) - - - - - - - - - - - - Band_7_1,DUF4339,SHOCT CMS3_k127_2138548_4 694427.Palpr_2237 4.861e-58 212.0 COG0707@1|root,COG0707@2|Bacteria,4NFRJ@976|Bacteroidetes,2FXKG@200643|Bacteroidia 976|Bacteroidetes M Glycosyl transferase family 1 - - - - - - - - - - - - Glyco_tran_28_C,Glyco_trans_1_3 CMS3_k127_2140907_0 926562.Oweho_0913 7.236e-91 305.0 COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1HY59@117743|Flavobacteriia,2PAD7@246874|Cryomorphaceae 976|Bacteroidetes F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh CMS3_k127_2140907_1 929703.KE386492_gene4373 2.63e-11 77.0 COG4886@1|root,COG4886@2|Bacteria 2|Bacteria S regulation of response to stimulus - - - - - - - - - - - - DUF1570,LRR_4,LRR_5 CMS3_k127_2149107_0 1124780.ANNU01000008_gene2650 7.043e-110 379.0 COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes,47PRM@768503|Cytophagia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS3_k127_2149107_1 313596.RB2501_08985 5.099e-07 54.0 COG0621@1|root,COG0621@2|Bacteria,4NDU6@976|Bacteroidetes,1HX6T@117743|Flavobacteriia 976|Bacteroidetes J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 CMS3_k127_2151711_4 1121904.ARBP01000007_gene2973 1.51e-49 181.0 COG0746@1|root,COG0746@2|Bacteria,4NMYW@976|Bacteroidetes,47NQP@768503|Cytophagia 976|Bacteroidetes H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 CMS3_k127_2151711_3 926549.KI421517_gene1968 7.138e-60 211.0 COG0315@1|root,COG0315@2|Bacteria,4NHA0@976|Bacteroidetes,47PU9@768503|Cytophagia 976|Bacteroidetes H MoaC family moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC CMS3_k127_2151711_2 472759.Nhal_1439 2.884e-61 236.0 COG3284@1|root,COG4251@1|root,COG3284@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 CMS3_k127_2151711_1 1121373.KB903625_gene3144 4.72e-80 275.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_2151711_0 1286632.P278_26030 2.518e-160 539.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia 976|Bacteroidetes P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_2151711_5 1123278.KB893546_gene4984 2.619e-26 123.0 COG0810@1|root,COG1629@1|root,COG4219@1|root,COG0810@2|Bacteria,COG1629@2|Bacteria,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,47M7Q@768503|Cytophagia 976|Bacteroidetes KMT PFAM BlaR1 peptidase M56 - - - - - - - - - - - - CarbopepD_reg_2,Peptidase_M56,Plug,TonB_C CMS3_k127_2153850_2 760192.Halhy_1885 4.859e-108 361.0 COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes,1IVD9@117747|Sphingobacteriia 976|Bacteroidetes S Phosphotriesterase family php - - ko:K07048 - - - - ko00000 - - - PTE CMS3_k127_2153850_1 32057.KB217478_gene1822 2.264e-109 366.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups wgaB - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 CMS3_k127_2153850_0 1168034.FH5T_12255 9.839e-284 879.0 COG0665@1|root,COG0665@2|Bacteria,4NFTJ@976|Bacteroidetes,2G18H@200643|Bacteroidia 976|Bacteroidetes E FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored CMS3_k127_2154933_2 313603.FB2170_10911 2.082e-23 100.0 COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1HXP9@117743|Flavobacteriia,2PHZI@252356|Maribacter 976|Bacteroidetes O prohibitin homologues - - - - - - - - - - - - Band_7 CMS3_k127_2154933_0 1121904.ARBP01000001_gene5820 3.533e-128 419.0 COG3239@1|root,COG3239@2|Bacteria,4NIC2@976|Bacteroidetes,47UEF@768503|Cytophagia 976|Bacteroidetes I Fatty acid desaturase alkB - 1.14.15.3 ko:K00496 ko00071,ko00930,map00071,map00930 - R01347,R02281,R06945 RC00478 ko00000,ko00001,ko01000 - - - FA_desaturase CMS3_k127_2154933_1 1122176.KB903544_gene728 5.418e-68 255.0 COG4251@1|root,COG4251@2|Bacteria,4NDUQ@976|Bacteroidetes,1IPY9@117747|Sphingobacteriia 976|Bacteroidetes T Phytochrome region - - - - - - - - - - - - CHASE3,GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_2,PAS_3,PAS_9,PHY,Response_reg CMS3_k127_2154933_3 1185876.BN8_05179 6.536e-07 54.0 COG1215@1|root,COG1215@2|Bacteria,4NG7F@976|Bacteroidetes,47PGR@768503|Cytophagia 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_2155761_1 56110.Oscil6304_6039 7.992e-59 224.0 COG0457@1|root,COG2319@1|root,COG4995@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria,COG4995@2|Bacteria,1GC4U@1117|Cyanobacteria,1HEM7@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - CHAT,TPR_12,WD40 CMS3_k127_2155761_2 313606.M23134_06281 1.789e-48 189.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NSC3@976|Bacteroidetes,47S66@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,TPR_2 CMS3_k127_2155761_0 880070.Cycma_3429 2.515e-208 670.0 2CEEY@1|root,348ZW@2|Bacteria,4P529@976|Bacteroidetes,47W4A@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2168590_2 1122931.AUAE01000026_gene2501 7.278e-10 64.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,22X4F@171551|Porphyromonadaceae 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_2168590_3 204536.SULAZ_0256 4.596e-08 56.0 COG2405@1|root,COG2405@2|Bacteria 2|Bacteria - - - - - ko:K07066 - - - - ko00000 - - - DUF3368 CMS3_k127_2168590_1 760192.Halhy_2477 6.624e-18 85.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_2168590_0 760192.Halhy_1854 4.874e-44 161.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_2170531_2 1189612.A33Q_2383 5.039e-32 133.0 COG2819@1|root,COG2819@2|Bacteria,4NUWU@976|Bacteroidetes,47WIG@768503|Cytophagia 976|Bacteroidetes S Putative esterase - - - - - - - - - - - - Esterase CMS3_k127_2170531_3 926562.Oweho_1638 1.032e-18 91.0 COG2801@1|root,COG2801@2|Bacteria,4NM64@976|Bacteroidetes,1HZ28@117743|Flavobacteriia 976|Bacteroidetes L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - rve CMS3_k127_2170531_1 575589.HMPREF0018_00559 1.594e-74 264.0 COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,1RRC6@1236|Gammaproteobacteria,3NSXU@468|Moraxellaceae 1236|Gammaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_2170531_0 1040989.AWZU01000028_gene3006 9.299e-214 677.0 COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria,2TVKJ@28211|Alphaproteobacteria,3JSJV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S FAD binding domain MA20_22130 - - ko:K07077 - - - - ko00000 - - - FAD_binding_2 CMS3_k127_2170531_4 1094558.ME5_00886 4.39e-05 46.0 COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,48SYD@772|Bartonellaceae 28211|Alphaproteobacteria P Sodium:sulfate symporter transmembrane region - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C CMS3_k127_2176548_3 449447.MAE_03780 6.561e-48 195.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria 2|Bacteria S peptidyl-tyrosine sulfation - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2 CMS3_k127_2176548_5 1408254.T458_09300 3.211e-05 55.0 COG0845@1|root,COG0845@2|Bacteria,1V5DX@1239|Firmicutes,4HMQM@91061|Bacilli,275J7@186822|Paenibacillaceae 91061|Bacilli M Barrel-sandwich domain of CusB or HlyD membrane-fusion yknX GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS3_k127_2176548_1 153721.MYP_3655 1.835e-54 201.0 COG5036@1|root,COG5036@2|Bacteria,4P2HI@976|Bacteroidetes,47V1T@768503|Cytophagia 976|Bacteroidetes P VTC domain - - - - - - - - - - - - VTC CMS3_k127_2176548_2 153721.MYP_3654 6.798e-54 197.0 COG1285@1|root,COG1285@2|Bacteria,4NTPJ@976|Bacteroidetes,47URT@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 CMS3_k127_2176548_0 1122226.AUHX01000007_gene2680 1.396e-54 198.0 COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,1I1FQ@117743|Flavobacteriia 976|Bacteroidetes S protein conserved in bacteria - - - ko:K09931 - - - - ko00000 - - - DUF2064 CMS3_k127_2176548_4 1114856.C496_21417 5.809e-22 101.0 COG0456@1|root,arCOG00833@2157|Archaea,2XXV1@28890|Euryarchaeota,23W3R@183963|Halobacteria 183963|Halobacteria S COG1246 N-acetylglutamate synthase and related acetyltransferases - - 2.3.1.1 ko:K00619 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 CMS3_k127_2179664_2 1122176.KB903531_gene3127 3.106e-30 128.0 2DSNZ@1|root,33GVQ@2|Bacteria,4NYCH@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2179664_4 880070.Cycma_4777 1.781e-05 51.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - CarboxypepD_reg,MORN_2,Plug,TonB_C CMS3_k127_2179664_3 46234.ANA_C10539 3.579e-11 66.0 2E14U@1|root,32WJW@2|Bacteria,1G8UP@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_2179664_1 760192.Halhy_1014 1.278e-37 146.0 COG1403@1|root,COG1403@2|Bacteria,4P4UB@976|Bacteroidetes 2|Bacteria L HNH endonuclease - - - - - - - - - - - - HNH,HNH_5 CMS3_k127_2179664_0 760192.Halhy_3858 2.046e-127 410.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,1IQZ0@117747|Sphingobacteriia 976|Bacteroidetes C NADH flavin oxidoreductase NADH oxidase - - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - Oxidored_FMN,Pyr_redox_2 CMS3_k127_218528_10 1410665.JNKR01000008_gene1102 6.158e-21 98.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4H31X@909932|Negativicutes 909932|Negativicutes L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 CMS3_k127_218528_13 1521187.JPIM01000059_gene2884 0.0001616 46.0 COG1722@1|root,COG1722@2|Bacteria,2G9U8@200795|Chloroflexi,3761B@32061|Chloroflexia 32061|Chloroflexia L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S CMS3_k127_218528_8 1124780.ANNU01000048_gene2123 5.247e-33 132.0 COG0629@1|root,COG0629@2|Bacteria,4NT9M@976|Bacteroidetes,47S1E@768503|Cytophagia 976|Bacteroidetes L Domain of unknown function (DUF3127) - - - - - - - - - - - - DUF3127 CMS3_k127_218528_7 1124780.ANNU01000048_gene2145 1.049e-36 142.0 COG0784@1|root,COG0784@2|Bacteria,4NRC9@976|Bacteroidetes,47QC7@768503|Cytophagia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_218528_4 1237149.C900_02383 3.817e-86 302.0 28KRY@1|root,2ZA9E@2|Bacteria,4NI1H@976|Bacteroidetes,47N4R@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_218528_1 929556.Solca_2813 5.851e-234 741.0 COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,1IQVN@117747|Sphingobacteriia 976|Bacteroidetes I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE CMS3_k127_218528_11 1173264.KI913949_gene1126 1.545e-12 79.0 COG4715@1|root,COG4715@2|Bacteria,1G37G@1117|Cyanobacteria,1HAEP@1150|Oscillatoriales 1117|Cyanobacteria S Zinc finger, SWIM domain protein - - - - - - - - - - - - SWIM CMS3_k127_218528_12 391600.ABRU01000033_gene723 8.406e-12 78.0 COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,2KF7P@204458|Caulobacterales 204458|Caulobacterales S PQQ-like domain - - - - - - - - - - - - PQQ_2,PQQ_3 CMS3_k127_218528_5 313606.M23134_03974 9.413e-58 213.0 29CCG@1|root,2ZZAY@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_218528_3 1122176.KB903609_gene5274 3.461e-224 706.0 COG0433@1|root,COG0433@2|Bacteria,4NF3P@976|Bacteroidetes,1IPH5@117747|Sphingobacteriia 976|Bacteroidetes S Bacterial protein of unknown function (DUF853) - - - ko:K06915 - - - - ko00000 - - - DUF853 CMS3_k127_218528_9 880073.Calab_0526 3.903e-21 109.0 COG1404@1|root,COG3291@1|root,COG3386@1|root,COG5276@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5276@2|Bacteria 2|Bacteria G gluconolactonase activity - - 3.1.1.17,3.2.1.4 ko:K01053,ko:K01179,ko:K07214,ko:K12287 ko00030,ko00053,ko00500,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00500,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751,R06200,R11307,R11308 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko02044,ko04147 - GH5,GH9 - Big_5,DUF285,Esterase,He_PIG,SGL CMS3_k127_218528_0 760192.Halhy_6043 8.457e-252 795.0 COG0514@1|root,COG0514@2|Bacteria,4NG10@976|Bacteroidetes,1IQU0@117747|Sphingobacteriia 976|Bacteroidetes L RQC recQ3 - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind CMS3_k127_218528_2 1239962.C943_02056 1.972e-224 702.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,47K9A@768503|Cytophagia 976|Bacteroidetes G Belongs to the xylose isomerase family xylA - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - - CMS3_k127_218528_6 497965.Cyan7822_5217 2.947e-40 164.0 COG2936@1|root,COG2936@2|Bacteria,1G1U8@1117|Cyanobacteria,3KHKK@43988|Cyanothece 1117|Cyanobacteria S X-Pro dipeptidyl-peptidase domain protein - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS3_k127_220501_1 1122605.KB893625_gene1977 7.217e-80 274.0 COG1028@1|root,COG1028@2|Bacteria,4NKYV@976|Bacteroidetes,1IYKY@117747|Sphingobacteriia 976|Bacteroidetes IQ KR domain - - - - - - - - - - - - adh_short_C2 CMS3_k127_220501_0 1122605.KB893625_gene1978 9.716e-172 545.0 COG4948@1|root,COG4948@2|Bacteria,4NP0T@976|Bacteroidetes 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_220501_2 266834.SM_b21156 5.092e-36 139.0 2A9W7@1|root,30Z46@2|Bacteria,1RIK9@1224|Proteobacteria,2U7GH@28211|Alphaproteobacteria,4B8Q3@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_2209852_3 761193.Runsl_2883 1.032e-58 212.0 28N7K@1|root,2ZBC9@2|Bacteria,4NHU8@976|Bacteroidetes,47N9I@768503|Cytophagia 976|Bacteroidetes S Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - - - - - - - - - - Cu2_monoox_C CMS3_k127_2209852_1 504472.Slin_5368 1.032e-190 605.0 COG4948@1|root,COG4948@2|Bacteria,4NFH1@976|Bacteroidetes,47MTW@768503|Cytophagia 976|Bacteroidetes M Enolase C-terminal domain-like - - - - - - - - - - - - MR_MLE_C CMS3_k127_2209852_0 761193.Runsl_2750 1.097e-250 796.0 COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,47KXP@768503|Cytophagia 976|Bacteroidetes CG PFAM Cytochrome c, class I - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C,DUF1080,PA14 CMS3_k127_2209852_2 762903.Pedsa_2198 2.362e-149 481.0 COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,1INRW@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the LDH2 MDH2 oxidoreductase family - - - - - - - - - - - - Ldh_2 CMS3_k127_2209852_5 1307759.JOMJ01000004_gene2718 9.192e-15 83.0 COG0500@1|root,COG2226@2|Bacteria,1N73D@1224|Proteobacteria,42XDU@68525|delta/epsilon subdivisions,2WTBP@28221|Deltaproteobacteria,2MBEV@213115|Desulfovibrionales 28221|Deltaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 CMS3_k127_2209852_6 1120951.AUBG01000015_gene3476 0.000543 50.0 COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1HXGK@117743|Flavobacteriia 976|Bacteroidetes H Methyltransferase - - - - - - - - - - - - Methyltransf_23 CMS3_k127_2209852_4 1121904.ARBP01000001_gene5605 1.844e-41 160.0 COG2207@1|root,COG2207@2|Bacteria,4PMN6@976|Bacteroidetes 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - DUF1835 CMS3_k127_2236725_1 1124780.ANNU01000033_gene1333 9.089e-183 587.0 COG1215@1|root,COG4124@1|root,COG1215@2|Bacteria,COG4124@2|Bacteria,4NEK9@976|Bacteroidetes,47KAY@768503|Cytophagia 976|Bacteroidetes M Cellulose synthase - - 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - Glyco_hydro_26,Glyco_hydro_2_C,Glyco_transf_21 CMS3_k127_2236725_0 1237149.C900_00818 5.099e-207 657.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia 976|Bacteroidetes J Amidase - - - - - - - - - - - - Amidase CMS3_k127_2236725_6 1392498.JQLH01000001_gene3775 3.552e-37 143.0 COG1393@1|root,COG1393@2|Bacteria,4NSAW@976|Bacteroidetes,1I450@117743|Flavobacteriia,2PHJZ@252356|Maribacter 976|Bacteroidetes P ArsC family - - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC CMS3_k127_2236725_7 1313421.JHBV01000030_gene2160 1.406e-13 85.0 COG1572@1|root,COG2911@1|root,COG2931@1|root,COG3391@1|root,COG3897@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG3897@2|Bacteria,4PN0F@976|Bacteroidetes,1IWTM@117747|Sphingobacteriia 976|Bacteroidetes P major pilin protein fima - - - - - - - - - - - - LTD,Laminin_G_3 CMS3_k127_2236725_8 1123508.JH636443_gene5001 4.243e-13 83.0 COG1404@1|root,COG2931@1|root,COG3210@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,2J2J4@203682|Planctomycetes 203682|Planctomycetes OU Calx-beta domain - - - - - - - - - - - - Calx-beta CMS3_k127_2236725_4 1107311.Q767_01615 2.682e-67 259.0 COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium 976|Bacteroidetes G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - He_PIG,I-set,Ig_3,SBBP CMS3_k127_2236725_3 1178825.ALIH01000002_gene1036 2.102e-87 297.0 COG0177@1|root,COG0177@2|Bacteria,4NE7K@976|Bacteroidetes,1HWQK@117743|Flavobacteriia 976|Bacteroidetes L TIGRFAM TIGR02757 family protein - - - - - - - - - - - - DUF2400 CMS3_k127_2236725_5 313598.MED152_12649 9.947e-51 189.0 COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,1HY3J@117743|Flavobacteriia,3VVQ8@52959|Polaribacter 976|Bacteroidetes S Protease prsW family - - - - - - - - - - - - PrsW-protease CMS3_k127_2236725_2 1124780.ANNU01000023_gene3238 2.056e-95 323.0 COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MGC@768503|Cytophagia 976|Bacteroidetes K PFAM Periplasmic binding protein LacI transcriptional regulator cytR - - ko:K02529,ko:K05499 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CMS3_k127_2236725_9 1166018.FAES_4903 7.025e-10 64.0 COG2105@1|root,COG2105@2|Bacteria,4NUSS@976|Bacteroidetes,47S6A@768503|Cytophagia 976|Bacteroidetes S Gamma-glutamyl cyclotransferase, AIG2-like - - - - - - - - - - - - GGACT CMS3_k127_2236890_1 984262.SGRA_3992 1.584e-22 106.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - BSP,CHU_C,CarbopepD_reg_2,PKD,SprB CMS3_k127_2236890_0 926549.KI421517_gene2441 1.013e-161 527.0 COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia 976|Bacteroidetes S Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 CMS3_k127_2236890_2 634994.GCWU000323_02437 7.369e-11 67.0 COG3187@1|root,COG3187@2|Bacteria,37B3Z@32066|Fusobacteria 32066|Fusobacteria O META domain protein - - - - - - - - - - - - META CMS3_k127_2242071_3 1229276.DI53_3039 8.846e-32 128.0 COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes,1IQTT@117747|Sphingobacteriia 976|Bacteroidetes J Pseudouridine synthase - - 5.4.99.23,5.4.99.24 ko:K06179,ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 CMS3_k127_2242071_4 1408422.JHYF01000003_gene710 1.441e-28 124.0 COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,36GX1@31979|Clostridiaceae 186801|Clostridia S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 CMS3_k127_2242071_2 1227739.Hsw_2977 9.333e-33 132.0 COG1366@1|root,COG1366@2|Bacteria,4NTPB@976|Bacteroidetes,47R1F@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - - - - - - - - - - STAS,STAS_2 CMS3_k127_2242071_1 391596.PBAL39_01002 1.086e-81 281.0 COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,1IPJ5@117747|Sphingobacteriia 976|Bacteroidetes S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B_2 CMS3_k127_2242071_0 945713.IALB_1798 2.751e-96 321.0 COG1738@1|root,COG1738@2|Bacteria 2|Bacteria S queuosine salvage CP_0807 - - ko:K09125 - - - - ko00000 - - - Vut_1 CMS3_k127_2242071_5 1296415.JACC01000052_gene3686 6.994e-07 61.0 2C1Y9@1|root,2Z8Q2@2|Bacteria,4NI0A@976|Bacteroidetes,1HY8H@117743|Flavobacteriia,2YH0Y@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2243633_0 1122179.KB890426_gene3942 2.94e-159 513.0 28HUE@1|root,2Z815@2|Bacteria,4NHK5@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2266281_1 1313421.JHBV01000138_gene1199 9.869e-16 84.0 COG0457@1|root,COG0457@2|Bacteria,4NQ10@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_2266281_0 643867.Ftrac_1104 9.503e-17 94.0 COG4249@1|root,COG4249@2|Bacteria,4NKHX@976|Bacteroidetes,47UFX@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,TPR_16 CMS3_k127_2266281_2 397287.C807_01231 3.749e-05 48.0 COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia,27P7B@186928|unclassified Lachnospiraceae 186801|Clostridia K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_227359_4 926562.Oweho_3003 2.919e-16 84.0 COG1253@1|root,COG1253@2|Bacteria,4NDZ7@976|Bacteroidetes,1HXF3@117743|Flavobacteriia,2PABH@246874|Cryomorphaceae 976|Bacteroidetes S Transporter associated domain gldE - - - - - - - - - - - CBS,CorC_HlyC,DUF21 CMS3_k127_227359_3 1120965.AUBV01000002_gene255 6.469e-30 125.0 COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,47QZT@768503|Cytophagia 976|Bacteroidetes L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB CMS3_k127_227359_1 694427.Palpr_0255 1.782e-78 274.0 COG1194@1|root,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,2FNMQ@200643|Bacteroidia,22WUP@171551|Porphyromonadaceae 976|Bacteroidetes L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 CMS3_k127_227359_2 929556.Solca_3519 1.226e-33 131.0 COG0776@1|root,COG0776@2|Bacteria,4NT0D@976|Bacteroidetes,1ISXQ@117747|Sphingobacteriia 976|Bacteroidetes L Belongs to the bacterial histone-like protein family hupA - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding CMS3_k127_227359_6 926549.KI421517_gene646 2.327e-14 83.0 COG0457@1|root,COG0457@2|Bacteria,4NEV2@976|Bacteroidetes,47KT9@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 CMS3_k127_227359_7 984262.SGRA_2566 1.161e-07 53.0 2DTGS@1|root,33K9M@2|Bacteria,4NYMF@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_227359_0 1237149.C900_04526 1.461e-170 550.0 COG1530@1|root,COG1530@2|Bacteria,4NED1@976|Bacteroidetes,47KC6@768503|Cytophagia 976|Bacteroidetes J ribonuclease, Rne Rng family rng - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 CMS3_k127_227359_5 1288963.ADIS_1185 2.973e-15 86.0 COG1196@1|root,COG1196@2|Bacteria,4NHAC@976|Bacteroidetes,47MGD@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - ko:K09892 - - - - ko00000,ko03036 - - - - CMS3_k127_2276519_0 1408473.JHXO01000001_gene2036 1.744e-177 569.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_2276519_3 46234.ANA_C13517 4.404e-31 126.0 COG1487@1|root,COG1487@2|Bacteria,1G8NQ@1117|Cyanobacteria,1HSQK@1161|Nostocales 1117|Cyanobacteria S Large family of predicted nucleotide-binding domains - - - - - - - - - - - - PIN CMS3_k127_2276519_1 1121875.KB907547_gene3300 1.028e-48 177.0 COG3759@1|root,COG3759@2|Bacteria,4NQA8@976|Bacteroidetes,1I2SZ@117743|Flavobacteriia 976|Bacteroidetes S membrane - - - ko:K08987 - - - - ko00000 - - - DUF1304 CMS3_k127_2276519_2 1166018.FAES_0157 2.116e-40 156.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_2278664_4 204669.Acid345_3597 1.494e-14 79.0 COG4319@1|root,COG4319@2|Bacteria,3Y89C@57723|Acidobacteria,2JNBD@204432|Acidobacteriia 204432|Acidobacteriia S SnoaL-like domain - - - - - - - - - - - - SnoaL_3 CMS3_k127_2278664_0 1250232.JQNJ01000001_gene3217 4.747e-136 453.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process pelC - - ko:K21008 ko02025,map02025 - - - ko00000,ko00001 - - - LpoB CMS3_k127_2278664_3 926550.CLDAP_09390 1.09e-28 126.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_6 CMS3_k127_2278664_1 1137281.D778_02693 6.329e-101 332.0 COG0110@1|root,COG0110@2|Bacteria,4NH27@976|Bacteroidetes,1IIUF@117743|Flavobacteriia 976|Bacteroidetes S Hexapeptide repeat of succinyl-transferase maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac CMS3_k127_2278664_2 391587.KAOT1_01579 6.293e-67 230.0 COG1505@1|root,COG1505@2|Bacteria,4NM0V@976|Bacteroidetes,1I0XU@117743|Flavobacteriia 976|Bacteroidetes E Prolyl oligopeptidase, N-terminal beta-propeller domain - - - - - - - - - - - - Peptidase_S9,Peptidase_S9_N CMS3_k127_2282802_2 1366046.HIMB11_01639 7.613e-160 514.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,3ZGD2@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria C COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases MA20_39380 - 1.14.13.127 ko:K05712 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06786,R06787 RC00236 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS3_k127_2282802_3 1336208.JADY01000004_gene3711 5.266e-127 413.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TQUY@28211|Alphaproteobacteria,2JRCR@204441|Rhodospirillales 204441|Rhodospirillales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_2282802_4 1349785.BAUG01000040_gene2139 7.97e-24 102.0 COG4327@1|root,COG4327@2|Bacteria,4NSV7@976|Bacteroidetes,1I3X5@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4212) - - - - - - - - - - - - DUF4212 CMS3_k127_2282802_0 1121904.ARBP01000009_gene4270 1.145e-229 723.0 COG4147@1|root,COG4147@2|Bacteria,4NHPT@976|Bacteroidetes,47JSK@768503|Cytophagia 976|Bacteroidetes S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF CMS3_k127_2282802_1 1408433.JHXV01000027_gene3728 2.364e-162 533.0 COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia 976|Bacteroidetes KT regulator - - - - - - - - - - - - GerE,Reg_prop,Y_Y_Y CMS3_k127_2286722_1 1250232.JQNJ01000001_gene1899 5.552e-209 659.0 COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,1HZJZ@117743|Flavobacteriia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like,SusD-like_2 CMS3_k127_2286722_0 760192.Halhy_3701 1.477e-260 808.0 COG4948@1|root,COG4948@2|Bacteria,4NE9A@976|Bacteroidetes,1IPDK@117747|Sphingobacteriia 976|Bacteroidetes M Mandelate racemase muconate lactonizing enzyme, N-terminal - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_229033_1 929562.Emtol_2433 2.721e-103 350.0 COG1228@1|root,COG1228@2|Bacteria,4NKV0@976|Bacteroidetes,47TDT@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_229033_0 1123248.KB893317_gene4264 6.971e-105 354.0 COG1228@1|root,COG1228@2|Bacteria,4NKV0@976|Bacteroidetes 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_2301272_2 1121904.ARBP01000008_gene3255 7.852e-152 484.0 COG4948@1|root,COG4948@2|Bacteria,4NEPP@976|Bacteroidetes,47M8J@768503|Cytophagia 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_2301272_0 1121875.KB907550_gene736 1.197e-225 712.0 COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,1HZSK@117743|Flavobacteriia 976|Bacteroidetes P sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase CMS3_k127_2301272_3 1121875.KB907549_gene1716 7.978e-33 130.0 2DZVD@1|root,32VJZ@2|Bacteria,4NUB2@976|Bacteroidetes,1I482@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - ydhR CMS3_k127_2301272_1 1237149.C900_00918 4.848e-197 627.0 COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,47K49@768503|Cytophagia 976|Bacteroidetes L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF CMS3_k127_23198_2 926550.CLDAP_24680 3.554e-132 426.0 COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi 200795|Chloroflexi C PFAM acyl-CoA dehydrogenase domain protein - - 1.3.8.8 ko:K00255,ko:K11731 ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320 M00087 R01279,R03777,R03857,R03990,R04751,R04754,R08089 RC00052,RC01893 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_23198_1 1313421.JHBV01000029_gene1884 9.861e-184 581.0 COG0183@1|root,COG0183@2|Bacteria,4NJ3Q@976|Bacteroidetes,1J086@117747|Sphingobacteriia 976|Bacteroidetes I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS3_k127_23198_0 1313421.JHBV01000029_gene1886 2.079e-274 861.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1IQBZ@117747|Sphingobacteriia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 CMS3_k127_23198_3 314278.NB231_12069 7.821e-05 51.0 291G3@1|root,33XP4@2|Bacteria,1NW6I@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS3_k127_2322681_3 929556.Solca_1231 1.131e-21 100.0 COG2265@1|root,COG2265@2|Bacteria,4PKBS@976|Bacteroidetes,1IRCR@117747|Sphingobacteriia 976|Bacteroidetes J (SAM)-dependent - - - - - - - - - - - - Cons_hypoth95,Methyltransf_15 CMS3_k127_2322681_2 526227.Mesil_2803 1.11e-117 388.0 COG4638@1|root,COG4638@2|Bacteria 2|Bacteria P Rieske (2fe-2S) - - 1.14.15.7 ko:K00499 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A CMS3_k127_2322681_1 251221.35212927 1.489e-130 433.0 COG0405@1|root,COG0405@2|Bacteria,1G20A@1117|Cyanobacteria 1117|Cyanobacteria E PFAM Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS3_k127_2322681_0 313606.M23134_06853 1.861e-156 510.0 COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,47KD5@768503|Cytophagia 976|Bacteroidetes M PFAM Uncharacterised BCR, COG1649 - - - - - - - - - - - - GHL10 CMS3_k127_2323593_8 1124780.ANNU01000036_gene19 2.367e-05 46.0 COG1215@1|root,COG1215@2|Bacteria,4NEG0@976|Bacteroidetes,47KET@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_2323593_7 1168289.AJKI01000012_gene285 1.582e-06 61.0 2BUJT@1|root,32VAI@2|Bacteria,4NSUJ@976|Bacteroidetes,2G2HM@200643|Bacteroidia,3XJQE@558415|Marinilabiliaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2323593_3 1124780.ANNU01000061_gene918 5.016e-135 441.0 COG0501@1|root,COG0501@2|Bacteria,4NESF@976|Bacteroidetes,47KTS@768503|Cytophagia 976|Bacteroidetes O Zn-dependent protease with chaperone function - - 3.4.24.84 ko:K03799,ko:K06013 ko00900,ko01130,map00900,map01130 M00743 R09845 RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N CMS3_k127_2323593_4 1122176.KB903555_gene3740 8.659e-62 220.0 COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes 976|Bacteroidetes K - catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding CMS3_k127_2323593_2 1313301.AUGC01000001_gene1467 2.378e-225 714.0 COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes 976|Bacteroidetes E Peptidase family M1 - - - - - - - - - - - - Leuk-A4-hydro_C,Peptidase_M1 CMS3_k127_2323593_6 1233951.IO90_16705 4.113e-31 138.0 2EY9E@1|root,33RHY@2|Bacteria,4P11Y@976|Bacteroidetes,1I88I@117743|Flavobacteriia,3HI3P@358033|Chryseobacterium 976|Bacteroidetes S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - DUF2723 CMS3_k127_2323593_1 1120968.AUBX01000012_gene2799 3.75e-304 948.0 COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia 976|Bacteroidetes K TIGRFAM competence protein ComEA helix-hairpin-helix repeat region yhgF - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF CMS3_k127_2323593_5 406124.ACPC01000005_gene3572 1.269e-57 203.0 COG3832@1|root,COG3832@2|Bacteria,1UA2K@1239|Firmicutes,4IKBZ@91061|Bacilli,1ZGDN@1386|Bacillus 91061|Bacilli J glyoxalase III activity - - - - - - - - - - - - Polyketide_cyc2 CMS3_k127_2323593_0 1124780.ANNU01000032_gene1259 0.0 1398.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,47K8Q@768503|Cytophagia 976|Bacteroidetes E Vitamin B12 dependent methionine synthase activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans CMS3_k127_2360495_6 761193.Runsl_1947 2.67e-108 364.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_2360495_1 1121904.ARBP01000002_gene7185 1.414e-178 566.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JS8@768503|Cytophagia 976|Bacteroidetes I Belongs to the thiolase family atoB - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS3_k127_2360495_5 880073.Calab_0156 1.511e-134 435.0 COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria 2|Bacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_2360495_0 1121904.ARBP01000028_gene1680 8.826e-319 985.0 COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,47JMW@768503|Cytophagia 976|Bacteroidetes I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C CMS3_k127_2360495_4 1121904.ARBP01000004_gene880 8.447e-148 475.0 COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CMS3_k127_2360495_2 1121904.ARBP01000004_gene882 6.919e-173 551.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,47NI5@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 CMS3_k127_2360495_3 643867.Ftrac_1642 3.415e-149 480.0 COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,47MDN@768503|Cytophagia 976|Bacteroidetes CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS3_k127_2360495_7 153721.MYP_1811 1.135e-11 64.0 COG0066@1|root,COG0066@2|Bacteria,4NDVY@976|Bacteroidetes,47NNG@768503|Cytophagia 976|Bacteroidetes E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C CMS3_k127_2364415_0 925409.KI911562_gene479 7.335e-132 433.0 COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,1IR6S@117747|Sphingobacteriia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_2364415_1 153721.MYP_4536 1.024e-85 290.0 COG1774@1|root,COG1774@2|Bacteria,4NENX@976|Bacteroidetes,47M8P@768503|Cytophagia 976|Bacteroidetes S PFAM PSP1 C-terminal conserved region - - - - - - - - - - - - PSP1 CMS3_k127_2368821_2 1121904.ARBP01000005_gene4578 1.842e-38 145.0 COG1082@1|root,COG1082@2|Bacteria,4NIWS@976|Bacteroidetes,47K4W@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N CMS3_k127_2368821_3 929562.Emtol_1467 1.355e-24 114.0 COG3279@1|root,COG3279@2|Bacteria,4NJ3A@976|Bacteroidetes,47KQ2@768503|Cytophagia 976|Bacteroidetes KT PFAM LytTr DNA-binding region - - - - - - - - - - - - LytTR CMS3_k127_2368821_1 1122179.KB890430_gene4291 2.446e-46 177.0 2ASFK@1|root,31HVJ@2|Bacteria,4NQMQ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2368821_0 1123248.KB893334_gene2751 8.187e-162 526.0 COG1506@1|root,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - Tannase CMS3_k127_2373848_2 485918.Cpin_1884 1.514e-142 473.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - DUF11,DUF3367,SASA CMS3_k127_2373848_5 215803.DB30_3927 5.244e-07 56.0 COG3292@1|root,COG4191@1|root,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria 28221|Deltaproteobacteria T ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA,PAS_9,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_2373848_3 313606.M23134_08123 5.934e-131 447.0 COG4886@1|root,COG5635@1|root,COG4886@2|Bacteria,COG5635@2|Bacteria,4P0SG@976|Bacteroidetes 976|Bacteroidetes T Leucine-rich repeat (LRR) protein - - - - - - - - - - - - LRR_4 CMS3_k127_2373848_1 1120966.AUBU01000002_gene2068 3.241e-174 557.0 COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,47KAQ@768503|Cytophagia 976|Bacteroidetes F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,ASL_C,Lyase_1 CMS3_k127_2373848_6 1392490.JHZX01000001_gene3501 5.796e-05 52.0 COG4969@1|root,COG4969@2|Bacteria,4NVUE@976|Bacteroidetes,1I5FG@117743|Flavobacteriia 976|Bacteroidetes NU Belongs to the N-Me-Phe pilin family - - - - - - - - - - - - - CMS3_k127_2373848_4 153721.MYP_4806 5.68e-11 76.0 COG0810@1|root,COG0810@2|Bacteria,4NES0@976|Bacteroidetes,47NZ2@768503|Cytophagia 976|Bacteroidetes M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - - - - - - - - - - - CMS3_k127_2373848_0 760192.Halhy_2051 4.147e-306 983.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria 2|Bacteria T PhoQ Sensor - - 4.6.1.1 ko:K01768,ko:K16923,ko:K19694 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00582,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 3.A.1.28 - - 7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_2376514_0 315730.BcerKBAB4_3502 2.829e-36 149.0 COG2819@1|root,COG2819@2|Bacteria,1V0WQ@1239|Firmicutes,4HK6I@91061|Bacilli,1ZQ8Q@1386|Bacillus 91061|Bacilli S Putative esterase besA - - ko:K07017 - - - - ko00000 - - - Esterase CMS3_k127_2376514_1 616991.JPOO01000003_gene2291 1.488e-21 95.0 COG2159@1|root,COG2159@2|Bacteria,4PJ9Q@976|Bacteroidetes,1IEPW@117743|Flavobacteriia,23IFH@178469|Arenibacter 976|Bacteroidetes S amidohydrolase - - - - - - - - - - - - - CMS3_k127_2383703_1 742817.HMPREF9449_01394 5.361e-86 297.0 COG0841@1|root,COG0841@2|Bacteria,4NE3H@976|Bacteroidetes,2FN4H@200643|Bacteroidia,22WXN@171551|Porphyromonadaceae 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS3_k127_2383703_0 470145.BACCOP_01877 2.534e-95 332.0 COG1538@1|root,COG1538@2|Bacteria,4NGXM@976|Bacteroidetes,2FMD9@200643|Bacteroidia,4AMSY@815|Bacteroidaceae 976|Bacteroidetes MU Psort location OuterMembrane, score - - - - - - - - - - - - OEP CMS3_k127_2383703_2 1469557.JSWF01000025_gene1406 1.502e-65 236.0 COG2197@1|root,COG2197@2|Bacteria,4NHYB@976|Bacteroidetes,1HYWM@117743|Flavobacteriia 976|Bacteroidetes KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE CMS3_k127_2383703_3 1028801.RG1141_PA00840 2.188e-61 218.0 COG4221@1|root,COG4221@2|Bacteria,1REP9@1224|Proteobacteria,2U8RV@28211|Alphaproteobacteria,4BAC3@82115|Rhizobiaceae 28211|Alphaproteobacteria S KR domain - - - - - - - - - - - - adh_short CMS3_k127_2407834_1 153721.MYP_3800 2.071e-73 256.0 COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,47MF3@768503|Cytophagia 976|Bacteroidetes E Peptidase S46 - - - - - - - - - - - - Peptidase_S46 CMS3_k127_2407834_0 1121904.ARBP01000005_gene4837 1.515e-208 660.0 COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia 976|Bacteroidetes S PFAM Neutral alkaline nonlysosomal ceramidase - - - - - - - - - - - - Ceramidase_alk CMS3_k127_2407834_3 1195236.CTER_5219 6.202e-51 196.0 COG4948@1|root,COG4948@2|Bacteria,1V715@1239|Firmicutes,24YHT@186801|Clostridia 186801|Clostridia M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C CMS3_k127_2407834_2 1121904.ARBP01000012_gene1387 8.406e-56 198.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47JHZ@768503|Cytophagia 976|Bacteroidetes G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis - - - - - - - - - - - - PFK CMS3_k127_2407910_0 1191523.MROS_1042 1.027e-127 434.0 COG0308@1|root,COG0308@2|Bacteria 2|Bacteria E peptide catabolic process - - - - - - - - - - - - Peptidase_M1 CMS3_k127_2416533_0 1499967.BAYZ01000103_gene3772 5.336e-170 542.0 COG5441@1|root,COG5441@2|Bacteria 2|Bacteria S Uncharacterised protein family (UPF0261) - - - - - - - - - - - - UPF0261 CMS3_k127_2416533_1 243090.RB10921 2.098e-123 401.0 COG5564@1|root,COG5564@2|Bacteria,2IYG4@203682|Planctomycetes 203682|Planctomycetes S Phosphoenolpyruvate hydrolase-like - - - - - - - - - - - - PEP_hydrolase CMS3_k127_2416533_2 153721.MYP_4301 8.83e-28 130.0 COG1652@1|root,COG3409@1|root,COG1652@2|Bacteria,COG3409@2|Bacteria,4NWVZ@976|Bacteroidetes,47XVN@768503|Cytophagia 2|Bacteria M Domain of unknown function (DUF4157) MA20_21840 - 3.2.1.96,3.5.1.28 ko:K01227,ko:K01448,ko:K03791,ko:K13277,ko:K17733 ko00511,ko01503,ko02024,map00511,map01503,map02024 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110 - GH19 - Amidase_3,DUF1036,DUF4157,Glucosaminidase,PG_binding_1,SH3_3 CMS3_k127_2418378_1 1120965.AUBV01000013_gene1342 1.52e-85 286.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,47PAR@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 CMS3_k127_2418378_6 313606.M23134_07873 5.424e-22 98.0 COG2261@1|root,COG2261@2|Bacteria 2|Bacteria S Transglycosylase associated protein mltA - - - - - - - - - - - Transgly_assoc CMS3_k127_2418378_7 1121887.AUDK01000013_gene3319 2.581e-17 84.0 2A441@1|root,30SP3@2|Bacteria,4PEPA@976|Bacteroidetes,1IN3F@117743|Flavobacteriia,2NXKY@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2418378_0 313606.M23134_00763 1.5e-110 366.0 COG0332@1|root,COG0332@2|Bacteria,4NKY5@976|Bacteroidetes,47QSA@768503|Cytophagia 976|Bacteroidetes I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_2418378_3 1237149.C900_04326 2.948e-58 226.0 COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia 976|Bacteroidetes S COGs COG1033 exporter of the RND superfamily protein - - - ko:K07003 - - - - ko00000 - - - MMPL CMS3_k127_2418378_5 350058.Mvan_1079 6.237e-35 145.0 COG0596@1|root,COG0596@2|Bacteria,2HEN1@201174|Actinobacteria,23ABM@1762|Mycobacteriaceae 201174|Actinobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 CMS3_k127_2418378_2 1408433.JHXV01000005_gene2448 2.446e-70 256.0 2BXK4@1|root,32XG0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_2418378_4 1408322.JHYK01000003_gene1126 3.115e-39 151.0 COG3882@1|root,COG3882@2|Bacteria,1TTCC@1239|Firmicutes,24A4U@186801|Clostridia,27J7E@186928|unclassified Lachnospiraceae 186801|Clostridia Q HAD-superfamily phosphatase, subfamily IIIC - - - - - - - - - - - - Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,NIF,PP-binding,ketoacyl-synt CMS3_k127_2437726_2 926549.KI421517_gene3853 0.0009687 42.0 COG3291@1|root,COG3291@2|Bacteria,4NJW2@976|Bacteroidetes,47K98@768503|Cytophagia 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C CMS3_k127_2437726_0 153721.MYP_1591 1.705e-85 295.0 COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,47N57@768503|Cytophagia 976|Bacteroidetes S LexA-binding, inner membrane-associated putative hydrolase - - - ko:K07038 - - - - ko00000 - - - YdjM CMS3_k127_2437726_1 761193.Runsl_5090 1.11e-82 283.0 COG0111@1|root,COG0111@2|Bacteria,4NEMQ@976|Bacteroidetes,47K6J@768503|Cytophagia 976|Bacteroidetes EH D-isomer specific 2-hydroxyacid dehydrogenase serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C CMS3_k127_2453571_0 1168289.AJKI01000024_gene1485 8.036e-187 595.0 COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 - - - ko00000,ko00001,ko02000 2.A.21,2.A.21.8 - - HD_4,SSF CMS3_k127_2453571_3 1122179.KB890417_gene3261 1.908e-77 280.0 COG2353@1|root,COG2885@1|root,COG2353@2|Bacteria,COG2885@2|Bacteria,4PPP4@976|Bacteroidetes 976|Bacteroidetes M chlorophyll binding - - - - - - - - - - - - - CMS3_k127_2453571_2 616991.JPOO01000001_gene3962 1.395e-135 441.0 COG3173@1|root,COG3173@2|Bacteria,4NFE7@976|Bacteroidetes,1I04P@117743|Flavobacteriia 976|Bacteroidetes S Phosphotransferase enzyme family - - - - - - - - - - - - APH CMS3_k127_2453571_1 929562.Emtol_3283 2.827e-140 462.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug CMS3_k127_2456898_0 641524.ADICYQ_1336 5.875e-282 872.0 COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes 976|Bacteroidetes P COG3119 Arylsulfatase A - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_2456898_1 313603.FB2170_01941 1.175e-250 779.0 COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,1HZQ7@117743|Flavobacteriia,2PGBQ@252356|Maribacter 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_2456898_2 1121012.AUKX01000052_gene2581 3.251e-39 149.0 COG1409@1|root,COG1409@2|Bacteria,4NKP0@976|Bacteroidetes,1HY1S@117743|Flavobacteriia,23H8T@178469|Arenibacter 976|Bacteroidetes S Calcineurin-like phosphoesterase - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Metallophos,SASA CMS3_k127_2472286_1 946077.W5A_05418 1.722e-31 126.0 COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,1HWVP@117743|Flavobacteriia 976|Bacteroidetes J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 CMS3_k127_2472286_4 1123008.KB905697_gene3171 9.9e-12 72.0 2E8SV@1|root,3333M@2|Bacteria,4NSHV@976|Bacteroidetes,2FV1F@200643|Bacteroidia,22YEX@171551|Porphyromonadaceae 976|Bacteroidetes S Domain of unknown function (DUF4293) - - - - - - - - - - - - DUF4293 CMS3_k127_2472286_0 1313421.JHBV01000016_gene5685 1.854e-77 292.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1IXZE@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_7 CMS3_k127_2472286_2 1122179.KB890469_gene493 8.583e-24 118.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 CMS3_k127_2472286_3 385682.AFSL01000020_gene2180 4.334e-19 103.0 COG4886@1|root,COG4886@2|Bacteria,4NI2K@976|Bacteroidetes,2FVD8@200643|Bacteroidia,3XKWQ@558415|Marinilabiliaceae 976|Bacteroidetes S Leucine rich repeat - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - CBM_4_9,He_PIG,Ig_3,LRRNT_2,LRR_1,LRR_4,LRR_8,Peptidase_M64,VCBS CMS3_k127_2491322_5 598659.NAMH_1700 2.28e-06 51.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2YPJX@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS3_k127_2491322_0 1237149.C900_03253 4.805e-282 879.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia 976|Bacteroidetes O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 CMS3_k127_2491322_1 1121904.ARBP01000002_gene7036 4.433e-120 391.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,47MT1@768503|Cytophagia 976|Bacteroidetes IQ Enoyl-(Acyl carrier protein) reductase uxuB_1 - - - - - - - - - - - adh_short_C2 CMS3_k127_2491322_3 1089547.KB913013_gene3249 3.973e-13 77.0 2CJWV@1|root,2ZBKR@2|Bacteria,4NMFQ@976|Bacteroidetes,47PBB@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2491322_4 1168034.FH5T_13465 1.018e-06 59.0 2D3S1@1|root,32TFH@2|Bacteria,4NUIB@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2491322_2 1123278.KB893488_gene6119 1.384e-75 265.0 COG0451@1|root,COG0451@2|Bacteria,4NEMN@976|Bacteroidetes,47KEU@768503|Cytophagia 976|Bacteroidetes GM NmrA-like family dfrA - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase CMS3_k127_2505602_1 1123057.P872_23345 8.066e-19 91.0 COG2259@1|root,COG2259@2|Bacteria,4NP94@976|Bacteroidetes,47QI2@768503|Cytophagia 976|Bacteroidetes S DoxX - - - - - - - - - - - - DoxX CMS3_k127_2505602_2 518766.Rmar_2466 1.897e-06 57.0 COG3103@1|root,COG3103@2|Bacteria 2|Bacteria T Sh3 type 3 domain protein - - - - - - - - - - - - - CMS3_k127_2505602_0 153721.MYP_2236 5.991e-93 310.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,47K8Q@768503|Cytophagia 976|Bacteroidetes E Vitamin B12 dependent methionine synthase activation metH - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans CMS3_k127_2508263_1 880070.Cycma_0495 3.207e-35 136.0 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,47K6D@768503|Cytophagia 976|Bacteroidetes L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA CMS3_k127_2508263_0 1124780.ANNU01000028_gene977 1.296e-110 367.0 COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,47KKM@768503|Cytophagia 976|Bacteroidetes S UPF0365 protein - - - - - - - - - - - - YdfA_immunity CMS3_k127_251232_0 530564.Psta_3017 6.372e-211 667.0 COG1053@1|root,COG1053@2|Bacteria,2IXHQ@203682|Planctomycetes 203682|Planctomycetes C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored CMS3_k127_251232_4 530564.Psta_3016 2.669e-29 127.0 COG1477@1|root,COG1477@2|Bacteria 2|Bacteria H protein flavinylation apbE_1 - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE CMS3_k127_251232_1 530564.Psta_3015 9.691e-149 483.0 COG0673@1|root,COG0673@2|Bacteria,2IY5Y@203682|Planctomycetes 203682|Planctomycetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_251232_3 1443665.JACA01000049_gene5418 3.401e-42 157.0 COG3682@1|root,COG3682@2|Bacteria,4NT4V@976|Bacteroidetes,1I2YY@117743|Flavobacteriia,2YJP7@290174|Aquimarina 976|Bacteroidetes K Penicillinase repressor - - - - - - - - - - - - Penicillinase_R CMS3_k127_251232_2 1122179.KB890491_gene4407 3.346e-61 226.0 COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,1ITJ2@117747|Sphingobacteriia 976|Bacteroidetes KT PFAM Peptidase M56, BlaR1 - - - - - - - - - - - - Peptidase_M56 CMS3_k127_2512849_1 497965.Cyan7822_2624 1.632e-48 181.0 COG3265@1|root,COG3265@2|Bacteria,1G60D@1117|Cyanobacteria,3KI3B@43988|Cyanothece 1117|Cyanobacteria F TIGRFAM carbohydrate kinase, thermoresistant glucokinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - SKI CMS3_k127_2512849_0 1121904.ARBP01000003_gene6128 4.774e-161 515.0 COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,47K7I@768503|Cytophagia 976|Bacteroidetes P Outer membrane receptor for ferrienterochelin and colicins - - - ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_2528812_1 1237149.C900_02635 7.006e-48 176.0 COG1309@1|root,COG1309@2|Bacteria,4NEUA@976|Bacteroidetes,47P97@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CMS3_k127_2528812_0 1142394.PSMK_09460 1.513e-73 269.0 COG4225@1|root,COG4225@2|Bacteria 2|Bacteria S unsaturated chondroitin disaccharide hydrolase activity - - - - - - - - - - - - - CMS3_k127_2546877_14 1346330.M472_07130 1.458e-52 187.0 COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,1ISH0@117747|Sphingobacteriia 976|Bacteroidetes J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 CMS3_k127_2546877_25 742767.HMPREF9456_00436 3.433e-13 69.0 COG0257@1|root,COG0257@2|Bacteria,4NXGE@976|Bacteroidetes,2FVEE@200643|Bacteroidia,22YYG@171551|Porphyromonadaceae 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 CMS3_k127_2546877_21 945713.IALB_0934 7.571e-34 130.0 COG0361@1|root,COG0361@2|Bacteria 2|Bacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a CMS3_k127_2546877_3 742817.HMPREF9449_02674 3.8e-107 353.0 COG0024@1|root,COG0024@2|Bacteria,4NERQ@976|Bacteroidetes,2FM24@200643|Bacteroidia,22X5Z@171551|Porphyromonadaceae 976|Bacteroidetes E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 CMS3_k127_2546877_1 926562.Oweho_3079 6.145e-153 495.0 COG0201@1|root,COG0201@2|Bacteria,4NEPU@976|Bacteroidetes,1HWR7@117743|Flavobacteriia,2PA4H@246874|Cryomorphaceae 976|Bacteroidetes U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY CMS3_k127_2546877_13 1313301.AUGC01000006_gene98 1.256e-54 195.0 COG0200@1|root,COG0200@2|Bacteria,4NNFQ@976|Bacteroidetes 976|Bacteroidetes J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A CMS3_k127_2546877_24 1189612.A33Q_0462 4.187e-19 88.0 COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes,47S6M@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 CMS3_k127_2546877_9 1121904.ARBP01000006_gene3829 6.185e-68 234.0 COG0098@1|root,COG0098@2|Bacteria,4NG1Z@976|Bacteroidetes,47M7G@768503|Cytophagia 976|Bacteroidetes J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C CMS3_k127_2546877_19 860228.Ccan_04580 2.96e-35 137.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,1I2S3@117743|Flavobacteriia,1ES1A@1016|Capnocytophaga 976|Bacteroidetes J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p CMS3_k127_2546877_7 1122179.KB890458_gene666 5.248e-71 244.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,1IRC9@117747|Sphingobacteriia 976|Bacteroidetes J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 CMS3_k127_2546877_11 1346330.M472_07080 6.355e-59 206.0 COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1IS0B@117747|Sphingobacteriia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 CMS3_k127_2546877_20 1237149.C900_01049 6.648e-35 134.0 COG0199@1|root,COG0199@2|Bacteria,4NQ6N@976|Bacteroidetes,47QB0@768503|Cytophagia 976|Bacteroidetes J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 CMS3_k127_2546877_6 1121104.AQXH01000010_gene2435 2.698e-76 261.0 COG0094@1|root,COG0094@2|Bacteria,4NEGY@976|Bacteroidetes,1IPX4@117747|Sphingobacteriia 976|Bacteroidetes J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C CMS3_k127_2546877_18 709991.Odosp_2323 1.096e-35 138.0 COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,2FT5V@200643|Bacteroidia,22Y4Z@171551|Porphyromonadaceae 976|Bacteroidetes J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 CMS3_k127_2546877_12 525245.HMPREF0044_0409 1.427e-57 202.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4D5QH@85005|Actinomycetales 201174|Actinobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 CMS3_k127_2546877_17 929556.Solca_3018 2.433e-38 144.0 COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1IT9T@117747|Sphingobacteriia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 CMS3_k127_2546877_26 1168034.FH5T_12855 1.651e-11 66.0 COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,2FUJB@200643|Bacteroidia 976|Bacteroidetes J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 CMS3_k127_2546877_10 743722.Sph21_1721 1.15e-60 211.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,1IRSN@117747|Sphingobacteriia 976|Bacteroidetes J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 CMS3_k127_2546877_4 743722.Sph21_1720 1.61e-105 346.0 COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,1IPKE@117747|Sphingobacteriia 976|Bacteroidetes J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C CMS3_k127_2546877_22 1408473.JHXO01000006_gene1287 1.493e-28 121.0 COG0091@1|root,COG0091@2|Bacteria,4NQ8E@976|Bacteroidetes,2FS3J@200643|Bacteroidia 976|Bacteroidetes J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 CMS3_k127_2546877_16 869213.JCM21142_31250 2.258e-43 159.0 COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,47QCA@768503|Cytophagia 976|Bacteroidetes J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 CMS3_k127_2546877_2 1313301.AUGC01000006_gene113 1.687e-123 400.0 COG0090@1|root,COG0090@2|Bacteria,4NE8G@976|Bacteroidetes 976|Bacteroidetes J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C CMS3_k127_2546877_23 1150600.ADIARSV_3627 8.831e-25 106.0 COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,1ITE2@117747|Sphingobacteriia 976|Bacteroidetes J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 CMS3_k127_2546877_8 1211813.CAPH01000013_gene459 9.685e-71 244.0 COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,2FM1W@200643|Bacteroidia,22U90@171550|Rikenellaceae 976|Bacteroidetes J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 CMS3_k127_2546877_5 743722.Sph21_1714 2.861e-90 301.0 COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,1IPGZ@117747|Sphingobacteriia 976|Bacteroidetes J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 CMS3_k127_2546877_15 1392488.JHZY01000004_gene2112 9.055e-47 170.0 COG0051@1|root,COG0051@2|Bacteria,4NQ65@976|Bacteroidetes,1I2VK@117743|Flavobacteriia,2XJF3@283735|Leeuwenhoekiella 976|Bacteroidetes J Ribosomal protein S10p/S20e rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 CMS3_k127_2546877_0 518766.Rmar_0839 8.505e-187 594.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,1FIQD@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CMS3_k127_257472_3 1121859.KB890755_gene1124 8.5e-133 436.0 COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47X9D@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_257472_13 926549.KI421517_gene2608 3.811e-38 145.0 COG1359@1|root,COG1359@2|Bacteria,4P4AS@976|Bacteroidetes,47V7Q@768503|Cytophagia 976|Bacteroidetes S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM CMS3_k127_257472_4 1380384.JADN01000003_gene444 8.944e-117 387.0 COG0598@1|root,COG0598@2|Bacteria,4NG3C@976|Bacteroidetes,1HXRX@117743|Flavobacteriia 976|Bacteroidetes P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA CMS3_k127_257472_12 929556.Solca_3970 4.183e-39 151.0 COG0622@1|root,COG0622@2|Bacteria,4PJA1@976|Bacteroidetes,1IZVM@117747|Sphingobacteriia 976|Bacteroidetes S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 CMS3_k127_257472_16 1121904.ARBP01000005_gene4869 2.544e-18 92.0 2CDAN@1|root,3134Z@2|Bacteria,4NNX4@976|Bacteroidetes,47XNP@768503|Cytophagia 976|Bacteroidetes S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_257472_2 509635.N824_14585 1.714e-213 676.0 COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IQU1@117747|Sphingobacteriia 976|Bacteroidetes E Oxidoreductase - - - - - - - - - - - - FAD_binding_2,GMC_oxred_C,GMC_oxred_N CMS3_k127_257472_14 35128.Thaps8273 3.422e-33 148.0 2CINB@1|root,2SVCS@2759|Eukaryota,2XH6X@2836|Bacillariophyta 2836|Bacillariophyta - - - - - - - - - - - - - - - CMS3_k127_257472_6 313606.M23134_04813 5.927e-80 280.0 2EHJH@1|root,336RS@2|Bacteria,4NX01@976|Bacteroidetes,47SDR@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_257472_7 1121904.ARBP01000006_gene3777 9.689e-76 258.0 COG4430@1|root,COG4430@2|Bacteria,4NQJJ@976|Bacteroidetes,47QKU@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF1905) - - - - - - - - - - - - DUF1905,OmdA CMS3_k127_257472_8 1122176.KB903546_gene967 1.468e-60 213.0 299NP@1|root,2ZWR1@2|Bacteria,4NP8Q@976|Bacteroidetes,1IYM3@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_257472_11 622637.KE124774_gene3268 5.656e-45 166.0 COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2TR4K@28211|Alphaproteobacteria,3703G@31993|Methylocystaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase CMS3_k127_257472_15 926549.KI421517_gene1751 3.315e-30 127.0 COG1595@1|root,COG1595@2|Bacteria,4NM7R@976|Bacteroidetes,47RDE@768503|Cytophagia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_257472_5 926556.Echvi_1849 9.962e-110 362.0 COG1082@1|root,COG1082@2|Bacteria,4NJF7@976|Bacteroidetes,47NQB@768503|Cytophagia 976|Bacteroidetes G PFAM Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_257472_0 1123057.P872_02175 1.704e-256 797.0 COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,47KMG@768503|Cytophagia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 CMS3_k127_257472_1 1122176.KB903537_gene1630 7.252e-243 757.0 COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1IRWG@117747|Sphingobacteriia 976|Bacteroidetes G Alpha amylase, catalytic domain amyB - - - - - - - - - - - Alpha-amylase,Alpha-amylase_C,Malt_amylase_C CMS3_k127_257472_9 1042376.AFPK01000051_gene937 4.231e-59 215.0 COG0457@1|root,COG0457@2|Bacteria,4NMM8@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19,TPR_8 CMS3_k127_257472_10 1443665.JACA01000007_gene128 4.285e-57 202.0 COG1278@1|root,COG1278@2|Bacteria,4NNNH@976|Bacteroidetes,1I1ZM@117743|Flavobacteriia,2YH9T@290174|Aquimarina 976|Bacteroidetes K Cold shock protein domain cspG - - - - - - - - - - - CSD CMS3_k127_2576992_0 344747.PM8797T_30871 5.767e-129 429.0 2DBKQ@1|root,2Z9U7@2|Bacteria,2IWVD@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - CMS3_k127_2576992_1 1296416.JACB01000001_gene3181 1.41e-62 218.0 COG0454@1|root,COG0456@2|Bacteria,4NPGI@976|Bacteroidetes,1I2EX@117743|Flavobacteriia 976|Bacteroidetes K GCN5 family acetyltransferase yjaB - - ko:K03827 - - - - ko00000,ko01000 - - - Acetyltransf_10 CMS3_k127_2583933_1 755732.Fluta_2051 1.413e-18 90.0 COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae 976|Bacteroidetes M Glycosyl transferase family 4 - - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - CoA_binding_3,Glycos_transf_4 CMS3_k127_2583933_0 1122225.AULQ01000002_gene496 5.803e-57 224.0 COG5448@1|root,COG5448@2|Bacteria,4NGRS@976|Bacteroidetes,1HZ9S@117743|Flavobacteriia 976|Bacteroidetes S Glycoside hydrolase family 24 - - - - - - - - - - - - - CMS3_k127_25940_3 929556.Solca_1507 8.432e-23 100.0 COG3193@1|root,COG3193@2|Bacteria,4NI6Y@976|Bacteroidetes,1IT3F@117747|Sphingobacteriia 976|Bacteroidetes S Pfam:SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_25940_0 1121904.ARBP01000009_gene4223 8.308e-63 232.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,4NF1F@976|Bacteroidetes,47MSJ@768503|Cytophagia 976|Bacteroidetes T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg CMS3_k127_25940_4 42256.RradSPS_1835 1.722e-16 92.0 COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRIR@84995|Rubrobacteria 84995|Rubrobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3 CMS3_k127_25940_2 761193.Runsl_4362 7.282e-32 128.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,47U5P@768503|Cytophagia 976|Bacteroidetes S ATPase domain predominantly from Archaea - - - ko:K06921 - - - - ko00000 - - - ATPase_2 CMS3_k127_25940_1 1267535.KB906767_gene5299 1.668e-62 217.0 COG1073@1|root,COG3250@1|root,COG1073@2|Bacteria,COG3250@2|Bacteria,3Y652@57723|Acidobacteria 57723|Acidobacteria G alpha beta - - - - - - - - - - - - - CMS3_k127_2604586_5 1150600.ADIARSV_1733 7.397e-45 166.0 COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 CMS3_k127_2604586_2 761193.Runsl_1709 2.037e-89 295.0 COG0377@1|root,COG0377@2|Bacteria,4NHZ2@976|Bacteroidetes,47J9U@768503|Cytophagia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 CMS3_k127_2604586_4 761193.Runsl_1710 8.927e-53 191.0 COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,47PNZ@768503|Cytophagia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa CMS3_k127_2604586_1 762903.Pedsa_1350 4.35e-208 651.0 COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR1E@117747|Sphingobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa CMS3_k127_2604586_0 385682.AFSL01000060_gene1815 1.222e-245 779.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FNTN@200643|Bacteroidia,3XINN@558415|Marinilabiliaceae 976|Bacteroidetes G Fibronectin type III-like domain - GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_2604586_3 83406.HDN1F_17460 1.228e-65 229.0 COG1028@1|root,COG1028@2|Bacteria,1QTUD@1224|Proteobacteria,1T1HG@1236|Gammaproteobacteria,1JC0R@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS3_k127_261492_1 452637.Oter_3131 3.885e-179 585.0 COG1874@1|root,COG1874@2|Bacteria 2|Bacteria G beta-galactosidase activity - - - - - - - - - - - - GHL6,Glyco_hydro_42,Glyco_hydro_42M CMS3_k127_261492_0 1123277.KB893206_gene3445 5.936e-226 721.0 COG3525@1|root,COG3525@2|Bacteria,4NH5U@976|Bacteroidetes 976|Bacteroidetes G domain, Protein - - - - - - - - - - - - Glyco_hydro_20b CMS3_k127_261492_5 1123276.KB893245_gene1777 4.083e-65 236.0 28PTH@1|root,2ZCER@2|Bacteria,4NN6T@976|Bacteroidetes,47PQ4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_261492_3 388413.ALPR1_12085 8.563e-115 383.0 28K3C@1|root,2Z9SH@2|Bacteria,4NKA2@976|Bacteroidetes,47NBG@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_261492_2 1242864.D187_010107 2.492e-139 452.0 COG0016@1|root,COG0016@2|Bacteria,1R9QP@1224|Proteobacteria 1224|Proteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily - - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - FDX-ACB,tRNA-synt_2d CMS3_k127_261492_4 867845.KI911784_gene457 2.675e-107 360.0 COG4638@1|root,COG4638@2|Bacteria,2G720@200795|Chloroflexi,377BT@32061|Chloroflexia 32061|Chloroflexia P PFAM Rieske 2Fe-2S domain protein - - 1.14.15.7 ko:K00479,ko:K00499 ko00260,map00260 - R07409 RC00087 ko00000,ko00001,ko01000 - - - Rieske,Ring_hydroxyl_A CMS3_k127_2618353_5 1121904.ARBP01000009_gene4334 1.497e-05 57.0 29T9R@1|root,30EGQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - TPR_19 CMS3_k127_2618353_2 1239962.C943_03442 9.36e-77 264.0 COG1354@1|root,COG1354@2|Bacteria,4NJQE@976|Bacteroidetes,47MUR@768503|Cytophagia 976|Bacteroidetes D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA CMS3_k127_2618353_3 533247.CRD_01467 3.8e-64 225.0 COG3145@1|root,COG3145@2|Bacteria,1G503@1117|Cyanobacteria,1HNPM@1161|Nostocales 1117|Cyanobacteria L 2OG-Fe(II) oxygenase superfamily alkB - - - - - - - - - - - 2OG-FeII_Oxy_2 CMS3_k127_2618353_0 580331.Thit_0290 3.839e-114 376.0 COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,247J8@186801|Clostridia,42FK9@68295|Thermoanaerobacterales 186801|Clostridia Q Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway psuG - 4.2.1.70 ko:K16329 ko00240,map00240 - R01055 RC00432,RC00433 ko00000,ko00001,ko01000 - - - Indigoidine_A CMS3_k127_2618353_1 1484460.JSWG01000005_gene2674 1.247e-100 340.0 COG2304@1|root,COG2304@2|Bacteria,4NEGD@976|Bacteroidetes,1HY72@117743|Flavobacteriia 976|Bacteroidetes P von Willebrand factor, type A - - - - - - - - - - - - VWA CMS3_k127_2618353_4 118168.MC7420_1348 1.548e-08 62.0 COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HA36@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - NB-ARC,TPR_12,TPR_7 CMS3_k127_2619260_1 1122176.KB903535_gene2022 4.17e-59 223.0 COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - - - - - - - - - - - CHU_C,PKD,SprB CMS3_k127_2619260_2 504472.Slin_5703 2.619e-45 171.0 COG2865@1|root,COG2865@2|Bacteria,4NGPG@976|Bacteroidetes,47N5X@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - AlbA_2 CMS3_k127_2619260_0 1122176.KB903609_gene5236 9.255e-70 245.0 COG0699@1|root,COG0699@2|Bacteria,4NTQB@976|Bacteroidetes 976|Bacteroidetes S PFAM Dynamin family - - - - - - - - - - - - Dynamin_N CMS3_k127_26236_1 1121904.ARBP01000003_gene6355 1.897e-128 417.0 COG4948@1|root,COG4948@2|Bacteria,4NFHR@976|Bacteroidetes,47KJ8@768503|Cytophagia 976|Bacteroidetes M PFAM Mandelate racemase muconate lactonizing - - 4.2.1.40 ko:K01706 ko00053,ko01100,map00053,map01100 - R02752,R08056 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_26236_0 1121904.ARBP01000003_gene6352 6.556e-136 447.0 COG2610@1|root,COG2610@2|Bacteria,4NJ5B@976|Bacteroidetes,47K2S@768503|Cytophagia 976|Bacteroidetes EG PFAM Gluconate transporter - - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease CMS3_k127_26236_2 1121904.ARBP01000003_gene6351 1.423e-92 310.0 COG3836@1|root,COG3836@2|Bacteria,4NH2V@976|Bacteroidetes,47JVN@768503|Cytophagia 976|Bacteroidetes G Belongs to the HpcH HpaI aldolase family - - 4.1.2.20,4.1.2.52,4.1.2.53 ko:K01630,ko:K02510,ko:K12660 ko00051,ko00053,ko00350,ko01120,map00051,map00053,map00350,map01120 - R01645,R01647,R02261,R02754,R03277 RC00307,RC00435,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI CMS3_k127_26236_5 479435.Kfla_1517 5.668e-47 182.0 COG0116@1|root,COG0116@2|Bacteria,2HUIS@201174|Actinobacteria,4DVNX@85009|Propionibacteriales 201174|Actinobacteria L Putative RNA methylase family UPF0020 - - - - - - - - - - - - UPF0020 CMS3_k127_26236_4 997346.HMPREF9374_0005 1.269e-48 184.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,27B90@186824|Thermoactinomycetaceae 91061|Bacilli I Enoyl-CoA hydratase/isomerase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 CMS3_k127_26236_6 985867.AEWF01000012_gene1289 7.287e-05 49.0 2CHMC@1|root,33I36@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_26236_3 1121890.AUDO01000030_gene1018 1.935e-68 241.0 COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1HXYG@117743|Flavobacteriia,2NYWA@237|Flavobacterium 976|Bacteroidetes D Cellulose biosynthesis protein BcsQ - - - - - - - - - - - - AAA_31 CMS3_k127_2643783_1 880070.Cycma_4552 4.432e-44 162.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,4NF4F@976|Bacteroidetes,47U87@768503|Cytophagia 976|Bacteroidetes C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C CMS3_k127_2643783_0 46234.ANA_C11950 6.426e-116 382.0 COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1HM34@1161|Nostocales 1117|Cyanobacteria F Catalyzes the conversion of dihydroorotate to orotate - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh CMS3_k127_2643783_2 935845.JADQ01000007_gene1675 5.51e-07 61.0 COG4733@1|root,COG4733@2|Bacteria,1V0X5@1239|Firmicutes,4HDRK@91061|Bacilli,26VBX@186822|Paenibacillaceae 91061|Bacilli DZ Fibronectin type 3 domain - - - - - - - - - - - - Cadherin-like CMS3_k127_2643783_3 1121957.ATVL01000009_gene997 0.0006644 51.0 COG3934@1|root,COG3934@2|Bacteria,4NJJS@976|Bacteroidetes,47SQ1@768503|Cytophagia 976|Bacteroidetes G Pkd domain containing protein - - - - - - - - - - - - Cellulase,DUF5060 CMS3_k127_2644885_3 760192.Halhy_1519 1.355e-41 158.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - FG-GAP,UnbV_ASPIC,VCBS CMS3_k127_2644885_0 1123278.KB893548_gene4748 4.365e-293 913.0 COG1554@1|root,COG1554@2|Bacteria,4NFG1@976|Bacteroidetes,47MTU@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 65, N-terminal domain kojP - - - - - - - - - - - Glyco_hydro_65N,Glyco_hydro_65m CMS3_k127_2644885_2 1121904.ARBP01000009_gene4389 1.651e-191 607.0 COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47JAV@768503|Cytophagia 976|Bacteroidetes I PAP2 superfamily - - - - - - - - - - - - PAP2 CMS3_k127_2644885_1 1121904.ARBP01000032_gene2026 8.82e-269 836.0 COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,47KNU@768503|Cytophagia 976|Bacteroidetes S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_2647749_3 1408433.JHXV01000021_gene1702 0.0003405 46.0 COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes,1ICP7@117743|Flavobacteriia,2PBGK@246874|Cryomorphaceae 976|Bacteroidetes M Transglycosylase SLT domain - - - - - - - - - - - - SLT CMS3_k127_2647749_0 760192.Halhy_3457 1.1e-122 402.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,1INXE@117747|Sphingobacteriia 976|Bacteroidetes M PFAM NAD dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd CMS3_k127_2647749_1 272134.KB731324_gene985 9.006e-81 276.0 COG1215@1|root,COG1215@2|Bacteria,1G5XD@1117|Cyanobacteria,1HB7J@1150|Oscillatoriales 1117|Cyanobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_2647749_2 700598.Niako_6780 1.066e-59 216.0 COG0438@1|root,COG0438@2|Bacteria,4NMHA@976|Bacteroidetes 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 CMS3_k127_2672584_0 313606.M23134_06836 0.0 1057.0 COG2185@1|root,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,47JW5@768503|Cytophagia 976|Bacteroidetes I Methylmalonyl-CoA mutase mutB - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase CMS3_k127_2672584_1 1237149.C900_03151 6.031e-165 526.0 COG0205@1|root,COG0205@2|Bacteria,4NGN7@976|Bacteroidetes,47TRF@768503|Cytophagia 976|Bacteroidetes F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK CMS3_k127_2672584_2 1288963.ADIS_2801 4.562e-163 522.0 COG1454@1|root,COG1454@2|Bacteria,4NIU1@976|Bacteroidetes,47NG0@768503|Cytophagia 976|Bacteroidetes C Iron-containing alcohol dehydrogenase fucO - 1.1.1.77 ko:K00048 ko00630,ko00640,ko01120,map00630,map00640,map01120 - R01781,R02257 RC00087,RC00099 ko00000,ko00001,ko01000 - - - Fe-ADH CMS3_k127_2672584_3 1004149.AFOE01000032_gene1649 0.000695 46.0 COG4251@1|root,COG4251@2|Bacteria,4PM7A@976|Bacteroidetes 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GAF,HATPase_c,HNOBA,HisKA,PAS_3,PAS_9,Response_reg CMS3_k127_2676787_2 313603.FB2170_14288 7.231e-63 219.0 COG3419@1|root,COG3419@2|Bacteria,4NGV9@976|Bacteroidetes 976|Bacteroidetes NU Tfp pilus assembly protein tip-associated adhesin - - - - - - - - - - - - PQQ,PQQ_2 CMS3_k127_2676787_1 1121930.AQXG01000004_gene2803 1.62e-97 325.0 COG0384@1|root,COG0384@2|Bacteria,4NEWM@976|Bacteroidetes,1IP44@117747|Sphingobacteriia 976|Bacteroidetes S Phenazine biosynthesis-like protein - - - - - - - - - - - - PhzC-PhzF CMS3_k127_2676787_0 504472.Slin_6603 8.216e-150 488.0 COG1409@1|root,COG1409@2|Bacteria,4NEYU@976|Bacteroidetes,47KM8@768503|Cytophagia 976|Bacteroidetes S PFAM metallophosphoesterase - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N CMS3_k127_2696592_3 1173029.JH980292_gene3693 0.000952 47.0 COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales 1117|Cyanobacteria A Wd40 repeat-containing protein - - - - - - - - - - - - AAA_35,WD40 CMS3_k127_2696592_0 1123248.KB893386_gene1917 2.714e-312 979.0 COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1IR88@117747|Sphingobacteriia 976|Bacteroidetes P TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CMS3_k127_2696592_1 1121007.AUML01000034_gene1750 1.374e-208 665.0 COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HY6N@117743|Flavobacteriia,2YIUH@290174|Aquimarina 976|Bacteroidetes P STAS domain - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp CMS3_k127_2696592_2 1004149.AFOE01000049_gene1932 4.145e-101 335.0 COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia 976|Bacteroidetes F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran CMS3_k127_2710645_1 1313301.AUGC01000007_gene631 4.166e-78 265.0 COG0040@1|root,COG0040@2|Bacteria,4NDW8@976|Bacteroidetes 976|Bacteroidetes E ATP phosphoribosyltransferase hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C CMS3_k127_2710645_0 926566.Terro_2593 5.096e-105 350.0 COG3119@1|root,COG3119@2|Bacteria,3Y6D1@57723|Acidobacteria,2JK8D@204432|Acidobacteriia 204432|Acidobacteriia P PFAM Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_272327_2 105559.Nwat_0326 8.578e-13 75.0 COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1X2ND@135613|Chromatiales 135613|Chromatiales KT PFAM sigma-54 factor interaction domain-containing protein - - - ko:K10941 ko02020,ko02025,ko05111,map02020,map02025,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_8,Sigma54_activat CMS3_k127_272327_0 1122176.KB903531_gene3083 5.006e-80 286.0 COG3291@1|root,COG3291@2|Bacteria,4P0B8@976|Bacteroidetes,1IVY1@117747|Sphingobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,SprB CMS3_k127_272327_1 313606.M23134_05381 1.44e-61 218.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,47NT4@768503|Cytophagia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_2730145_1 1121957.ATVL01000009_gene867 3.071e-174 561.0 COG3250@1|root,COG3250@2|Bacteria,4NGZH@976|Bacteroidetes,47M3M@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - - - - - - - - - - - Glyco_hydro_106,Glyco_hydro_2_N CMS3_k127_2730145_2 1392498.JQLH01000001_gene3349 5.725e-120 396.0 COG0388@1|root,COG0388@2|Bacteria,4PE65@976|Bacteroidetes,1IENF@117743|Flavobacteriia,2PIBH@252356|Maribacter 976|Bacteroidetes S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase CMS3_k127_2730145_0 1166018.FAES_0158 1.135e-238 765.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_2730145_3 1121904.ARBP01000027_gene714 2.106e-28 119.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_2730145_4 616991.JPOO01000003_gene61 3.002e-05 48.0 2E9F7@1|root,333NI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_2746003_1 1121904.ARBP01000002_gene7062 6.872e-272 855.0 COG3206@1|root,COG3206@2|Bacteria,4NH33@976|Bacteroidetes 976|Bacteroidetes M regulator of chromosome condensation, RCC1 - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_2746003_0 1317122.ATO12_04495 0.0 1457.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1HXIG@117743|Flavobacteriia,2YIFW@290174|Aquimarina 976|Bacteroidetes S BNR Asp-box repeat - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_2746003_2 1122176.KB903552_gene3695 7.884e-47 181.0 COG1672@1|root,COG2319@1|root,COG4249@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,COG4249@2|Bacteria,4NR06@976|Bacteroidetes,1IWX9@117747|Sphingobacteriia 976|Bacteroidetes L ATPase involved in DNA repair - - - - - - - - - - - - - CMS3_k127_2759447_4 202698.XP_007387753.1 0.0004353 44.0 KOG0272@1|root,KOG0272@2759|Eukaryota 2759|Eukaryota S U4 snRNA binding - - - - - - - - - - - - NACHT,WD40 CMS3_k127_2759447_3 1123270.ATUR01000002_gene2719 1.105e-07 59.0 COG1266@1|root,COG1266@2|Bacteria,1NJ72@1224|Proteobacteria,2VERN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_2759447_2 1121904.ARBP01000008_gene3409 8.923e-21 99.0 COG1595@1|root,COG1595@2|Bacteria,4NM7Z@976|Bacteroidetes 976|Bacteroidetes K RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_2759447_1 1336803.PHEL49_1730 1.023e-47 184.0 COG3712@1|root,COG3712@2|Bacteria,4NQUV@976|Bacteroidetes,1I1HJ@117743|Flavobacteriia,3VX63@52959|Polaribacter 976|Bacteroidetes PT FecR protein - - - - - - - - - - - - DUF4974,FecR CMS3_k127_2759447_0 1120968.AUBX01000010_gene1225 2.727e-157 515.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47K5R@768503|Cytophagia 976|Bacteroidetes P TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_2767822_1 518766.Rmar_1973 1.013e-106 352.0 COG1878@1|root,COG1878@2|Bacteria,4PIWM@976|Bacteroidetes,1FJPB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Putative cyclase - GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase CMS3_k127_2767822_0 1047013.AQSP01000140_gene2509 1.297e-181 595.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_2767822_2 1120950.KB892761_gene5848 1.931e-52 203.0 COG4225@1|root,COG4225@2|Bacteria,2GJB5@201174|Actinobacteria 201174|Actinobacteria S BNR repeat-containing family member - - - - - - - - - - - - BNR_4 CMS3_k127_2767822_3 746697.Aeqsu_0513 7.52e-06 52.0 2BYG5@1|root,32ZEB@2|Bacteria,4NVAD@976|Bacteroidetes,1I5VX@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_277818_0 1122176.KB903562_gene3429 1.003e-61 239.0 COG1649@1|root,COG5263@1|root,COG1649@2|Bacteria,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,1J0DZ@117747|Sphingobacteriia 976|Bacteroidetes KLT WG containing repeat - - - - - - - - - - - - WG_beta_rep CMS3_k127_277818_1 313595.P700755_001152 0.0005274 48.0 COG4886@1|root,COG4886@2|Bacteria,4PM8Z@976|Bacteroidetes,1IJN6@117743|Flavobacteriia,4C4GI@83612|Psychroflexus 2|Bacteria S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - Big_2,CarboxypepD_reg,LRR_5,Peptidase_S8 CMS3_k127_2801392_2 1048983.EL17_16410 1.548e-50 186.0 COG5507@1|root,COG5507@2|Bacteria,4PPFF@976|Bacteroidetes,47YM4@768503|Cytophagia 976|Bacteroidetes S NIPSNAP - - - - - - - - - - - - NIPSNAP CMS3_k127_2801392_4 1484460.JSWG01000003_gene765 3.407e-07 57.0 2BYV9@1|root,32X8F@2|Bacteria,4NTFV@976|Bacteroidetes,1I4SC@117743|Flavobacteriia 976|Bacteroidetes S Lipocalin-like domain - - - - - - - - - - - - Lipocalin_4 CMS3_k127_2801392_0 1121904.ARBP01000004_gene1100 3.313e-228 725.0 COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,47JV2@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - Glyco_hydro_2_N,SASA CMS3_k127_2801392_3 1089547.KB913013_gene4534 2.155e-41 168.0 COG4643@1|root,COG4914@1|root,COG4643@2|Bacteria,COG4914@2|Bacteria,4NTQ4@976|Bacteroidetes,47RZ9@768503|Cytophagia 976|Bacteroidetes P DNA integration - - - - - - - - - - - - DUF2204 CMS3_k127_2801392_1 1027273.GZ77_20730 4.114e-105 347.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,1XHJP@135619|Oceanospirillales 135619|Oceanospirillales S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF CMS3_k127_2813281_0 1406840.Q763_11820 8.047e-167 531.0 COG1960@1|root,COG1960@2|Bacteria,4NEKJ@976|Bacteroidetes,1HYD3@117743|Flavobacteriia,2NSBD@237|Flavobacterium 976|Bacteroidetes I acyl-CoA dehydrogenase gcdH - 1.3.8.6 ko:K00252 ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130 M00032 R02487,R02488,R10074 RC00052,RC00156 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_2813281_1 762903.Pedsa_2225 2.367e-123 423.0 COG1480@1|root,COG1480@2|Bacteria,4NEHV@976|Bacteroidetes,1IPKB@117747|Sphingobacteriia 976|Bacteroidetes S 7TM receptor with intracellular HD hydrolase - - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD CMS3_k127_2819943_1 1454007.JAUG01000022_gene1262 1.526e-87 291.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IPEF@117747|Sphingobacteriia 976|Bacteroidetes I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) accD5 - - - - - - - - - - - Carboxyl_trans CMS3_k127_2819943_3 471854.Dfer_2893 4.12e-60 218.0 COG2912@1|root,COG2912@2|Bacteria,4NF8R@976|Bacteroidetes,47JJ3@768503|Cytophagia 976|Bacteroidetes S Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core2 CMS3_k127_2819943_2 1123248.KB893336_gene2838 3.02e-69 243.0 COG3279@1|root,COG3279@2|Bacteria,4NPFH@976|Bacteroidetes,1IXDB@117747|Sphingobacteriia 976|Bacteroidetes T LytTr DNA-binding domain - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_2819943_0 153721.MYP_2522 4.335e-90 304.0 COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,47JSG@768503|Cytophagia 976|Bacteroidetes O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small CMS3_k127_2831262_0 1121904.ARBP01000006_gene3816 2.926e-300 942.0 COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NHVG@976|Bacteroidetes,47M7T@768503|Cytophagia 976|Bacteroidetes CG TIGRFAM membrane-bound dehydrogenase domain protein - - - - - - - - - - - - Cytochrom_C,GSDH,HEAT_2 CMS3_k127_2831262_1 1121904.ARBP01000033_gene3173 2.381e-81 277.0 COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,47K0A@768503|Cytophagia 976|Bacteroidetes I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom CMS3_k127_2838305_1 1408433.JHXV01000009_gene1280 2.268e-39 155.0 COG1757@1|root,COG1757@2|Bacteria,4NHP9@976|Bacteroidetes,1IIVE@117743|Flavobacteriia 976|Bacteroidetes C Na+/H+ antiporter family - - - - - - - - - - - - Na_H_antiporter CMS3_k127_2838305_2 1540257.JQMW01000011_gene2536 1.338e-33 144.0 COG2312@1|root,COG2312@2|Bacteria,1UEE1@1239|Firmicutes,24ABX@186801|Clostridia,36EG0@31979|Clostridiaceae 186801|Clostridia S Erythromycin esterase - - - - - - - - - - - - - CMS3_k127_2838305_3 1540257.JQMW01000011_gene2211 3.332e-25 119.0 COG2312@1|root,COG2312@2|Bacteria,1UEE1@1239|Firmicutes,24ABX@186801|Clostridia,36EG0@31979|Clostridiaceae 186801|Clostridia S Erythromycin esterase - - - - - - - - - - - - - CMS3_k127_2838305_4 1121935.AQXX01000127_gene1206 6.098e-10 69.0 COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,1S9AU@1236|Gammaproteobacteria,1XPNN@135619|Oceanospirillales 135619|Oceanospirillales T Phosphoglycerate mutase - - - - - - - - - - - - His_Phos_1 CMS3_k127_2838305_0 153721.MYP_964 1.004e-75 270.0 COG2234@1|root,COG2234@2|Bacteria,4NGPJ@976|Bacteroidetes,47NIK@768503|Cytophagia 976|Bacteroidetes S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 CMS3_k127_2846821_4 700598.Niako_2039 0.0005311 42.0 COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1IXPB@117747|Sphingobacteriia 976|Bacteroidetes T LytTr DNA-binding domain - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_2846821_1 247639.MGP2080_08836 9.847e-173 547.0 COG2020@1|root,COG2020@2|Bacteria,1NFH1@1224|Proteobacteria,1SDM5@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Ergosterol biosynthesis ERG4/ERG24 family - - 1.3.1.21,1.3.1.71 ko:K00213,ko:K00223 ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130 M00101,M00102 R01451,R01456,R05641,R07487,R07492 RC00138,RC00237 ko00000,ko00001,ko00002,ko01000 - - - ERG4_ERG24 CMS3_k127_2846821_3 247639.MGP2080_08831 2.938e-79 272.0 COG0300@1|root,COG0300@2|Bacteria,1RBH6@1224|Proteobacteria,1S7XU@1236|Gammaproteobacteria 1236|Gammaproteobacteria S KR domain - - - - - - - - - - - - adh_short CMS3_k127_2846821_2 925409.KI911562_gene173 2.435e-172 549.0 COG1373@1|root,COG1373@2|Bacteria,4NEMX@976|Bacteroidetes,1IRG9@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_2846821_0 760192.Halhy_2973 1.894e-287 916.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_2857667_0 1211813.CAPH01000018_gene947 2.828e-59 216.0 COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,2FPEC@200643|Bacteroidia 976|Bacteroidetes G Glycosyl hydrolase family 2, sugar binding domain protein - - - - - - - - - - - - Glyco_hydro_106,Glyco_hydro_2_N CMS3_k127_2857667_1 700598.Niako_2950 5.364e-16 80.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia 976|Bacteroidetes K Tetratricopeptide repeat - - - - - - - - - - - - Guanylate_cyc,HTH_18,TPR_16,TPR_2,TPR_8 CMS3_k127_2857667_2 306263.Cla_0420 4.655e-07 57.0 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,42WF6@68525|delta/epsilon subdivisions 1224|Proteobacteria D Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_10,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 CMS3_k127_2858906_0 1237149.C900_05830 0.0 1165.0 COG0188@1|root,COG0188@2|Bacteria,4NERI@976|Bacteroidetes,47JQZ@768503|Cytophagia 976|Bacteroidetes L Belongs to the type II topoisomerase GyrA ParC subunit family parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_topoisoIV CMS3_k127_2858906_1 269798.CHU_0307 1.481e-183 595.0 COG1807@1|root,COG1807@2|Bacteria,4PKJX@976|Bacteroidetes,47KCA@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 CMS3_k127_2881428_6 1107311.Q767_01975 2.469e-37 143.0 COG2315@1|root,COG2315@2|Bacteria,4NTRF@976|Bacteroidetes,1ID1Z@117743|Flavobacteriia,2NWYS@237|Flavobacterium 976|Bacteroidetes S YjbR - - - - - - - - - - - - YjbR CMS3_k127_2881428_9 879212.DespoDRAFT_02821 1.536e-28 119.0 COG5573@1|root,COG5573@2|Bacteria,1N9U9@1224|Proteobacteria,42X8Z@68525|delta/epsilon subdivisions,2WT8G@28221|Deltaproteobacteria,2MMB8@213118|Desulfobacterales 28221|Deltaproteobacteria S PIN domain - - - - - - - - - - - - PIN CMS3_k127_2881428_8 717606.PaecuDRAFT_0004 1.607e-31 129.0 COG0454@1|root,COG0456@2|Bacteria,1VAYG@1239|Firmicutes,4HKJE@91061|Bacilli,26X23@186822|Paenibacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_4 CMS3_k127_2881428_1 1122176.KB903609_gene5273 1.219e-176 564.0 COG1073@1|root,COG1073@2|Bacteria,4NFCA@976|Bacteroidetes 976|Bacteroidetes S PS-10 peptidase S37 - - - - - - - - - - - - Peptidase_S37 CMS3_k127_2881428_2 1408473.JHXO01000005_gene1746 7.856e-151 490.0 COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,2FQ3G@200643|Bacteroidia 976|Bacteroidetes P Arylsulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C CMS3_k127_2881428_3 1396418.BATQ01000175_gene2811 1.828e-59 209.0 COG3871@1|root,COG3871@2|Bacteria,46VIW@74201|Verrucomicrobia,2IVPR@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Pyridoxamine 5'-phosphate oxidase like - - - - - - - - - - - - Pyrid_ox_like CMS3_k127_2881428_5 240016.ABIZ01000001_gene4763 9.672e-55 203.0 COG0398@1|root,COG0398@2|Bacteria,46Z4H@74201|Verrucomicrobia,2IUX8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc CMS3_k127_2881428_10 376686.Fjoh_1434 1.185e-26 126.0 COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,1HXET@117743|Flavobacteriia,2NSPN@237|Flavobacterium 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - A2M_N CMS3_k127_2881428_7 760192.Halhy_6223 7.348e-35 147.0 28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,1ISNF@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_2881428_0 760192.Halhy_6222 2.345e-230 744.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IPMB@117747|Sphingobacteriia 976|Bacteroidetes P TonB-dependent receptor plug domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_2881428_4 649349.Lbys_0966 1.786e-55 196.0 COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes,47P92@768503|Cytophagia 976|Bacteroidetes S PFAM YeeE YedE family (DUF395) - - - ko:K07112 - - - - ko00000 - - - Sulf_transp CMS3_k127_2881428_11 641524.ADICYQ_3394 1.04e-21 94.0 COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47NY1@768503|Cytophagia 976|Bacteroidetes S PFAM YeeE YedE family (DUF395) - - - ko:K07112 - - - - ko00000 - - - Sulf_transp CMS3_k127_2887572_2 1349822.NSB1T_12460 1.524e-100 342.0 COG3882@1|root,COG3882@2|Bacteria,4NGY0@976|Bacteroidetes,2FMRH@200643|Bacteroidia,22YUG@171551|Porphyromonadaceae 976|Bacteroidetes Q FkbH domain protein - - - - - - - - - - - - HAD_2 CMS3_k127_2887572_1 1121286.AUMT01000009_gene1098 7.702e-109 363.0 COG1680@1|root,COG1680@2|Bacteria,4NQNA@976|Bacteroidetes,1I9RU@117743|Flavobacteriia,3ZR57@59732|Chryseobacterium 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_2887572_0 313603.FB2170_14823 8.614e-157 509.0 2919D@1|root,2ZNWG@2|Bacteria,4NMU5@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2890981_7 1122176.KB903531_gene2990 8.357e-73 258.0 COG4412@1|root,COG4412@2|Bacteria,4PM4A@976|Bacteroidetes,1IWTI@117747|Sphingobacteriia 976|Bacteroidetes UW Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,Peptidase_M36 CMS3_k127_2890981_3 700598.Niako_0794 4.413e-138 445.0 COG0714@1|root,COG0714@2|Bacteria,4NIE6@976|Bacteroidetes,1IW0P@117747|Sphingobacteriia 976|Bacteroidetes S SPTR ATPase associated with various cellular activities AAA_3 - - - - - - - - - - - - AAA_5 CMS3_k127_2890981_2 1120966.AUBU01000018_gene256 1.543e-204 644.0 COG2234@1|root,COG2234@2|Bacteria,4NENF@976|Bacteroidetes 976|Bacteroidetes S Peptidase m28 - - - - - - - - - - - - Peptidase_M28,fn3 CMS3_k127_2890981_9 926556.Echvi_4124 1.152e-20 93.0 COG2608@1|root,COG2608@2|Bacteria,4NURN@976|Bacteroidetes,47SAD@768503|Cytophagia 976|Bacteroidetes C PFAM Heavy-metal-associated domain - - - - - - - - - - - - HMA CMS3_k127_2890981_1 643867.Ftrac_2059 0.0 1098.0 COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,47MMN@768503|Cytophagia 976|Bacteroidetes P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase CMS3_k127_2890981_8 1168034.FH5T_20115 2.835e-61 216.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,2FQV3@200643|Bacteroidia 976|Bacteroidetes K transcriptional regulator (AraC family) - - - - - - - - - - - - HTH_18 CMS3_k127_2890981_4 153721.MYP_1447 5.837e-127 409.0 COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,47KHR@768503|Cytophagia 976|Bacteroidetes C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein frdB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_7,Fer4_8 CMS3_k127_2890981_0 1121904.ARBP01000005_gene4730 0.0 1102.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia 976|Bacteroidetes C TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C CMS3_k127_2890981_6 926556.Echvi_2794 4.222e-79 270.0 2CAZH@1|root,2Z7RU@2|Bacteria,4NGM5@976|Bacteroidetes,47NEV@768503|Cytophagia 976|Bacteroidetes S TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - - CMS3_k127_2890981_5 929556.Solca_3096 5.125e-90 300.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IP5K@117747|Sphingobacteriia 976|Bacteroidetes C Dihydrolipoyl dehydrogenase - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim CMS3_k127_2897182_0 925409.KI911562_gene669 0.0 1210.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IP40@117747|Sphingobacteriia 976|Bacteroidetes S SPTR ASPIC UnbV domain protein - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_2897182_3 929562.Emtol_0734 1.558e-193 613.0 COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,47M2K@768503|Cytophagia 976|Bacteroidetes I PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - - - - - - - - - - PAP2 CMS3_k127_2897182_2 929562.Emtol_0733 5.055e-233 734.0 COG1858@1|root,COG1858@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K02660 ko02020,ko02025,map02020,map02025 - - - ko00000,ko00001,ko02035,ko02044 - - - CCP_MauG,UnbV_ASPIC,VCBS CMS3_k127_2897182_5 391600.ABRU01000031_gene2924 1.086e-81 281.0 COG1524@1|root,COG1524@2|Bacteria,1Q0Y4@1224|Proteobacteria,2V5W5@28211|Alphaproteobacteria,2KIEI@204458|Caulobacterales 204458|Caulobacterales S Chitobiase/beta-hexosaminidase C-terminal domain - - - - - - - - - - - - PA14,Phosphodiest CMS3_k127_2897182_6 1237149.C900_04853 1.868e-64 225.0 COG2316@1|root,COG2316@2|Bacteria,4NU4P@976|Bacteroidetes 976|Bacteroidetes S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - HD CMS3_k127_2897182_7 1443665.JACA01000053_gene3293 7.299e-11 71.0 2CIHR@1|root,332YQ@2|Bacteria,4NVAM@976|Bacteroidetes,1I60E@117743|Flavobacteriia,2YIND@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2897182_1 1121904.ARBP01000012_gene1254 2.267e-247 773.0 COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,47N97@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_2897182_4 761193.Runsl_1185 6.738e-125 407.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHMI@976|Bacteroidetes,47K6B@768503|Cytophagia 976|Bacteroidetes CG Membrane-bound dehydrogenase domain protein - - - - - - - - - - - - Cytochrom_C,HEAT_2,PmoA CMS3_k127_2915208_0 439235.Dalk_4289 8.646e-242 766.0 COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,42M9A@68525|delta/epsilon subdivisions,2WJ3Y@28221|Deltaproteobacteria,2MJBT@213118|Desulfobacterales 28221|Deltaproteobacteria S PFAM peptidase S45 penicillin amidase - - 3.5.1.11,3.5.1.97 ko:K01434,ko:K07116 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase CMS3_k127_2915208_1 1120966.AUBU01000005_gene3743 4.527e-98 324.0 COG0135@1|root,COG0135@2|Bacteria,4NK5D@976|Bacteroidetes,47NUD@768503|Cytophagia 976|Bacteroidetes E N-(5'phosphoribosyl)anthranilate (PRA) isomerase - - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI CMS3_k127_2915208_3 1380384.JADN01000003_gene960 8.546e-16 77.0 COG1878@1|root,COG1878@2|Bacteria,4NEQD@976|Bacteroidetes,1HZJE@117743|Flavobacteriia 976|Bacteroidetes S Putative cyclase - - - - - - - - - - - - Cyclase CMS3_k127_2915208_2 1191460.F959_02166 1.21e-57 206.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria,3NK0A@468|Moraxellaceae 1236|Gammaproteobacteria S Predicted membrane protein (DUF2238) yjdF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08984 - - - - ko00000 - - - DUF2238 CMS3_k127_2915208_4 670307.HYPDE_24338 8.252e-11 67.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - - - - - - - - - - - Epimerase,NAD_binding_10 CMS3_k127_2923072_1 1358423.N180_18680 1.14e-58 205.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IP5K@117747|Sphingobacteriia 976|Bacteroidetes C Dihydrolipoyl dehydrogenase - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim CMS3_k127_2923072_0 1305737.JAFX01000001_gene1977 1.55e-207 660.0 COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,47JVG@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran CMS3_k127_2923072_2 269798.CHU_1616 8.141e-51 187.0 COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,47QDX@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family fecI - - - - - - - - - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_2928197_2 1123277.KB893174_gene5927 9.669e-87 317.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase,Reg_prop,Y_Y_Y CMS3_k127_2928197_0 1288963.ADIS_1633 9.366e-142 465.0 COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_2928197_1 1123058.KB894219_gene177 4.09e-87 297.0 28HAW@1|root,2Z7N4@2|Bacteria,4NG29@976|Bacteroidetes,1I07Q@117743|Flavobacteriia 976|Bacteroidetes S KilA-N - - - - - - - - - - - - KilA-N CMS3_k127_2928197_3 1305737.JAFX01000001_gene1313 2.507e-23 102.0 COG1397@1|root,COG1397@2|Bacteria,4NISQ@976|Bacteroidetes,47U70@768503|Cytophagia 976|Bacteroidetes O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH CMS3_k127_2932969_0 1122621.ATZA01000029_gene2758 0.0 1151.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1IQP6@117747|Sphingobacteriia 976|Bacteroidetes O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N CMS3_k127_2932969_7 641524.ADICYQ_0239 0.0002915 49.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - CarboxypepD_reg,MORN_2,Plug,TonB_C CMS3_k127_2932969_5 36874.HQ34_05585 0.0001077 50.0 COG0810@1|root,COG0810@2|Bacteria,4NW2E@976|Bacteroidetes,2FWGT@200643|Bacteroidia,23228@171551|Porphyromonadaceae 976|Bacteroidetes M Gram-negative bacterial TonB protein C-terminal - - - - - - - - - - - - Peptidase_M56,TonB_C CMS3_k127_2932969_3 1122225.AULQ01000002_gene492 1.486e-54 217.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes 976|Bacteroidetes MU calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Big_5,PKD CMS3_k127_2932969_4 153721.MYP_3039 2.669e-49 201.0 COG1520@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4PKNZ@976|Bacteroidetes 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_2932969_6 1408433.JHXV01000016_gene1879 0.000271 54.0 COG1524@1|root,COG1524@2|Bacteria,4PIF1@976|Bacteroidetes,1IGD1@117743|Flavobacteriia,2PBDT@246874|Cryomorphaceae 976|Bacteroidetes S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest CMS3_k127_2932969_2 1396141.BATP01000035_gene4098 1.855e-115 380.0 COG0083@1|root,COG0083@2|Bacteria,46STT@74201|Verrucomicrobia,2IUQV@203494|Verrucomicrobiae 203494|Verrucomicrobiae E GHMP kinases N terminal domain - - - - - - - - - - - - GHMP_kinases_C,GHMP_kinases_N CMS3_k127_2932969_1 1122176.KB903555_gene3748 4.769e-165 531.0 COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,1IPDH@117747|Sphingobacteriia 976|Bacteroidetes E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N CMS3_k127_2936466_0 761193.Runsl_2911 3.81e-103 345.0 COG0520@1|root,COG0520@2|Bacteria,4NF4G@976|Bacteroidetes,47M48@768503|Cytophagia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_2936466_1 700598.Niako_2529 1.868e-77 265.0 COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,1IS56@117747|Sphingobacteriia 976|Bacteroidetes S Conserved hypothetical protein (DUF2461) - - - - - - - - - - - - DUF2461 CMS3_k127_2944810_1 1237149.C900_04160 1.493e-46 175.0 COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47JM8@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - DUF3829,VWA,VWA_2 CMS3_k127_2944810_0 485918.Cpin_0692 6.46e-141 454.0 COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,1IPG1@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d CMS3_k127_2944810_3 1450525.JATV01000008_gene529 2.405e-17 90.0 COG4886@1|root,COG4886@2|Bacteria,4PI28@976|Bacteroidetes,1IGQH@117743|Flavobacteriia,2NXDI@237|Flavobacterium 976|Bacteroidetes S Leucine rich repeat - - - - - - - - - - - - LRR_8 CMS3_k127_2944810_2 1237149.C900_03168 2.748e-25 109.0 COG4270@1|root,COG4270@2|Bacteria,4NVXH@976|Bacteroidetes,47WJK@768503|Cytophagia 976|Bacteroidetes S Membrane - - - - - - - - - - - - DoxX CMS3_k127_295429_7 929703.KE386492_gene4402 1.808e-09 67.0 COG5527@1|root,COG5527@2|Bacteria,4NH90@976|Bacteroidetes 976|Bacteroidetes L Initiator Replication protein - - - - - - - - - - - - Rep_3 CMS3_k127_295429_3 1124780.ANNU01000008_gene2666 4.5e-125 409.0 COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_295429_4 1121904.ARBP01000013_gene459 1.509e-76 263.0 28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_295429_8 115417.EPrPW00000020929 8.252e-05 53.0 KOG3509@1|root,KOG3509@2759|Eukaryota,1MJUC@121069|Pythiales 121069|Pythiales S Kazal type serine protease inhibitors - - - - - - - - - - - - - CMS3_k127_295429_5 1121904.ARBP01000004_gene918 4.568e-72 248.0 COG3828@1|root,COG3828@2|Bacteria,4NNKV@976|Bacteroidetes,47UNQ@768503|Cytophagia 976|Bacteroidetes S Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_295429_1 616991.JPOO01000001_gene3033 6.663e-203 642.0 COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes,1I0MV@117743|Flavobacteriia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_295429_0 1089550.ATTH01000001_gene669 1.747e-227 722.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes EU Prolyl oligopeptidase family - - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 CMS3_k127_295429_2 313606.M23134_05389 5.975e-188 610.0 COG4772@1|root,COG4772@2|Bacteria,4NE9I@976|Bacteroidetes,47M2B@768503|Cytophagia 976|Bacteroidetes P TonB-dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_295429_6 81824.XP_001746397.1 8.87e-19 100.0 COG0457@1|root,KOG1840@2759|Eukaryota,38CFM@33154|Opisthokonta 33154|Opisthokonta Z microtubule motor activity - - - - - - - - - - - - TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_2959704_1 742725.HMPREF9450_01515 5.185e-114 376.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,22UWS@171550|Rikenellaceae 976|Bacteroidetes GK Glucokinase glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK CMS3_k127_2959704_0 326297.Sama_0299 3.142e-134 436.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,2QADA@267890|Shewanellaceae 1236|Gammaproteobacteria E PFAM peptidase T2 asparaginase 2 aga - 3.5.1.1,3.5.1.26 ko:K01424,ko:K01444 ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase_2 CMS3_k127_2959704_2 1121904.ARBP01000002_gene6683 2.209e-62 222.0 COG3142@1|root,COG3142@2|Bacteria,4NINY@976|Bacteroidetes,47NRE@768503|Cytophagia 976|Bacteroidetes P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC CMS3_k127_2959704_3 1192034.CAP_2816 2.632e-49 181.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - - - - - - - - - - - AhpC-TSA CMS3_k127_2959704_4 1123276.KB893264_gene4585 3.223e-12 74.0 2E16F@1|root,32WM9@2|Bacteria,4NU22@976|Bacteroidetes,47RBV@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2967012_5 1279009.ADICEAN_03191 1.328e-20 93.0 COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,47KCQ@768503|Cytophagia 976|Bacteroidetes E Tryptophan 2,3-dioxygenase kynA - 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase CMS3_k127_2967012_1 743722.Sph21_1337 6.329e-85 298.0 COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 CMS3_k127_2967012_6 1227739.Hsw_2893 4.244e-14 83.0 2BPYJ@1|root,32ISF@2|Bacteria,4NRVJ@976|Bacteroidetes,47QN3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_2967012_2 1042376.AFPK01000036_gene1913 5.184e-77 267.0 COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1HX4X@117743|Flavobacteriia,405TD@61432|unclassified Flavobacteriaceae 976|Bacteroidetes S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 CMS3_k127_2967012_0 491205.JARQ01000003_gene2090 2.802e-137 440.0 COG0207@1|root,COG0207@2|Bacteria,4NEC2@976|Bacteroidetes,1HX2F@117743|Flavobacteriia,3ZQ2J@59732|Chryseobacterium 976|Bacteroidetes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt CMS3_k127_2967012_3 485917.Phep_1262 1.311e-55 199.0 COG1607@1|root,COG1607@2|Bacteria,4NERA@976|Bacteroidetes,1IS80@117747|Sphingobacteriia 976|Bacteroidetes I PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT CMS3_k127_2967012_4 348824.LPU83_4017 7.318e-51 188.0 COG0580@1|root,COG0580@2|Bacteria 2|Bacteria U water channel activity glpF - - ko:K02440,ko:K06188 - - - - ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.2 - - MIP CMS3_k127_2968488_1 1123277.KB893184_gene3936 2.096e-58 206.0 COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,47PCM@768503|Cytophagia 976|Bacteroidetes T GAF domain-containing protein msrC - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF,GAF_2 CMS3_k127_2968488_0 1237149.C900_05056 3.61e-187 595.0 COG0617@1|root,COG0617@2|Bacteria,4NF1S@976|Bacteroidetes,47KFG@768503|Cytophagia 976|Bacteroidetes J Poly A polymerase head domain cca - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd CMS3_k127_2968488_2 760192.Halhy_1337 2e-27 131.0 COG2319@1|root,COG4995@1|root,COG2319@2|Bacteria,COG4995@2|Bacteria,4P49H@976|Bacteroidetes 976|Bacteroidetes H WD40 repeats - - - - - - - - - - - - CHAT CMS3_k127_2982482_3 1237149.C900_00828 1.709e-30 128.0 COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria,4NIIP@976|Bacteroidetes,47MXS@768503|Cytophagia 976|Bacteroidetes T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA,cNMP_binding CMS3_k127_2982482_1 1121481.AUAS01000005_gene1903 2.754e-123 404.0 COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,47KP7@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_2982482_4 1189620.AJXL01000069_gene3361 1.655e-26 111.0 COG2261@1|root,COG2261@2|Bacteria 2|Bacteria S Transglycosylase associated protein mltA - - - - - - - - - - - Transgly_assoc CMS3_k127_2982482_2 489825.LYNGBM3L_10620 2.03e-65 233.0 COG3315@1|root,COG3315@2|Bacteria,1G5DY@1117|Cyanobacteria,1HFS2@1150|Oscillatoriales 1117|Cyanobacteria H Leucine carboxyl methyltransferase - - - - - - - - - - - - LCM CMS3_k127_2982482_0 1121904.ARBP01000017_gene5093 1.103e-146 480.0 COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,47V4E@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase - - - - - - - - - - - - Fn3_assoc,Metallophos,PA14 CMS3_k127_2987113_0 1454007.JAUG01000089_gene725 5.417e-200 642.0 COG0553@1|root,COG0553@2|Bacteria,4NKAA@976|Bacteroidetes,1IWR1@117747|Sphingobacteriia 976|Bacteroidetes L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N CMS3_k127_2987113_3 375451.RD1_2927 3.764e-18 85.0 COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,2P3FI@2433|Roseobacter 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain MA20_09880 - - - - - - - - - - - AAA_16,Guanylate_cyc,SAM_1,SAM_2 CMS3_k127_2987113_2 926562.Oweho_2885 8.776e-44 164.0 COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1IHP5@117743|Flavobacteriia,2PBX5@246874|Cryomorphaceae 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 CMS3_k127_2987113_1 1121875.KB907549_gene1947 6.96e-81 273.0 COG1335@1|root,COG1335@2|Bacteria,4NP7C@976|Bacteroidetes,1I299@117743|Flavobacteriia 976|Bacteroidetes Q isochorismatase - - - - - - - - - - - - Isochorismatase CMS3_k127_2989056_0 1120951.AUBG01000006_gene517 7.373e-160 520.0 COG0457@1|root,COG0457@2|Bacteria,4NFMI@976|Bacteroidetes,1HZPZ@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 CMS3_k127_2989056_2 696369.KI912183_gene2076 1.37e-31 127.0 COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,24QN5@186801|Clostridia,2635X@186807|Peptococcaceae 186801|Clostridia S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 CMS3_k127_2989056_3 1123277.KB893176_gene3824 5.84e-23 102.0 COG1669@1|root,COG1669@2|Bacteria,4NVYQ@976|Bacteroidetes 976|Bacteroidetes S Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 CMS3_k127_2989056_1 553174.HMPREF0659_A6732 3.72e-47 180.0 COG5495@1|root,COG5495@2|Bacteria,4NI4M@976|Bacteroidetes,2FMCQ@200643|Bacteroidia 976|Bacteroidetes S NADP oxidoreductase coenzyme F420-dependent - - - - - - - - - - - - DUF2520,F420_oxidored,Rossmann-like CMS3_k127_2992901_3 1238450.VIBNISOn1_800011 5.101e-70 244.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria,1XSIS@135623|Vibrionales 135623|Vibrionales H Aldolase/RraA - - - - - - - - - - - - RraA-like CMS3_k127_2992901_1 313628.LNTAR_07891 4.832e-200 635.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity VVA1143 - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_2992901_2 926556.Echvi_2092 4.795e-159 508.0 COG2355@1|root,COG2355@2|Bacteria,4NDYZ@976|Bacteroidetes,47JHU@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M19, renal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 CMS3_k127_2992901_0 760192.Halhy_1895 1.636e-202 647.0 COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Heparinase II III-like protein - - - - - - - - - - - - DUF4962,Hepar_II_III CMS3_k127_2994207_1 143224.JQMD01000002_gene268 1.953e-128 417.0 COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes,1HZV4@117743|Flavobacteriia 976|Bacteroidetes G YdjC-like protein - - 3.5.1.105 ko:K03478 - - - - ko00000,ko01000 - - - YdjC CMS3_k127_2994207_2 1237149.C900_00020 9.084e-79 279.0 COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,47RSG@768503|Cytophagia 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_2994207_0 880071.Fleli_1650 2.487e-264 841.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47NPA@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS3_k127_3011700_6 1227739.Hsw_1150 6.325e-75 259.0 COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MCZ@768503|Cytophagia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_3011700_9 452471.Aasi_0450 1.207e-44 181.0 COG0658@1|root,COG0658@2|Bacteria,4NEJH@976|Bacteroidetes,47K9X@768503|Cytophagia 976|Bacteroidetes S TIGRFAM ComEC Rec2-related protein comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 CMS3_k127_3011700_5 1127673.GLIP_3023 1.989e-84 287.0 COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,1RMTD@1236|Gammaproteobacteria,4644D@72275|Alteromonadaceae 1236|Gammaproteobacteria S Belongs to the UPF0246 family yaaA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - ko:K09861 - - - - ko00000 - - - H2O2_YaaD CMS3_k127_3011700_7 1216967.L100_14817 1.094e-69 249.0 COG2374@1|root,COG2374@2|Bacteria,4NEHG@976|Bacteroidetes,1HX79@117743|Flavobacteriia,34PTC@308865|Elizabethkingia 976|Bacteroidetes S Endonuclease - - - - - - - - - - - - Exo_endo_phos CMS3_k127_3011700_1 929556.Solca_1899 3.515e-188 598.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1IPCA@117747|Sphingobacteriia 976|Bacteroidetes T COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains ntrX - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_3011700_4 1356852.N008_18920 1.398e-92 323.0 COG1404@1|root,COG1404@2|Bacteria,4NHEU@976|Bacteroidetes,47K1W@768503|Cytophagia 976|Bacteroidetes O Peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - Peptidase_S8 CMS3_k127_3011700_0 1121904.ARBP01000003_gene6415 2.229e-223 702.0 COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_3011700_2 1178825.ALIH01000007_gene1742 1.14e-122 400.0 COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,1HZCI@117743|Flavobacteriia 976|Bacteroidetes P membrane protein TerC alx - - ko:K05794 - - - - ko00000 - - - TerC CMS3_k127_3011700_8 1124780.ANNU01000008_gene2705 6.972e-52 192.0 COG2755@1|root,COG2755@2|Bacteria,4NMGQ@976|Bacteroidetes,47QU7@768503|Cytophagia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 CMS3_k127_3011700_3 760192.Halhy_6136 2.223e-111 361.0 COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1IQ15@117747|Sphingobacteriia 976|Bacteroidetes G Xylose isomerase - - 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 CMS3_k127_3017364_0 388413.ALPR1_08433 8.53e-244 778.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3031539_1 1121324.CLIT_2c02270 2.568e-156 508.0 COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia 186801|Clostridia C PFAM Radical SAM - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS3_k127_3031539_6 237368.SCABRO_03886 5.242e-29 120.0 2CCSR@1|root,32RWC@2|Bacteria,2J1M5@203682|Planctomycetes 203682|Planctomycetes S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP CMS3_k127_3031539_0 1124780.ANNU01000073_gene727 1.189e-225 710.0 COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,47MUV@768503|Cytophagia 976|Bacteroidetes O magnesium chelatase comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C CMS3_k127_3031539_3 1121859.KB890742_gene39 1.089e-84 290.0 COG0330@1|root,COG0330@2|Bacteria,4NEBV@976|Bacteroidetes,47JW8@768503|Cytophagia 976|Bacteroidetes O membrane protease - - - - - - - - - - - - Band_7 CMS3_k127_3031539_2 411490.ANACAC_01851 8.452e-96 323.0 COG3645@1|root,COG3645@2|Bacteria,1UBCR@1239|Firmicutes,24DJ3@186801|Clostridia 186801|Clostridia S Psort location Cytoplasmic, score dinD - - ko:K14623 - - - - ko00000,ko03400 - - - Bro-N CMS3_k127_3031539_5 118161.KB235922_gene1869 2.059e-34 139.0 COG4636@1|root,COG4636@2|Bacteria,1G4JH@1117|Cyanobacteria,3VJKV@52604|Pleurocapsales 1117|Cyanobacteria S Putative restriction endonuclease - - - - - - - - - - - - Uma2 CMS3_k127_3031539_4 880070.Cycma_0141 1.02e-53 196.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHMI@976|Bacteroidetes,47K6B@768503|Cytophagia 976|Bacteroidetes CG Membrane-bound dehydrogenase domain protein - - - - - - - - - - - - Cytochrom_C CMS3_k127_3036932_1 471854.Dfer_3218 8.871e-193 609.0 COG3356@1|root,COG3356@2|Bacteria,4NHGJ@976|Bacteroidetes,47N67@768503|Cytophagia 976|Bacteroidetes S PFAM Neutral alkaline nonlysosomal ceramidase - - - - - - - - - - - - - CMS3_k127_3036932_2 1121904.ARBP01000018_gene2704 1.221e-148 483.0 COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia 976|Bacteroidetes G BNR repeat-like domain - - - - - - - - - - - - BNR_2 CMS3_k127_3036932_4 471854.Dfer_3212 6.036e-90 312.0 28KPG@1|root,2ZA7K@2|Bacteria,4NFWJ@976|Bacteroidetes,47MDA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3036932_3 641524.ADICYQ_0562 3.177e-95 321.0 COG0657@1|root,COG0657@2|Bacteria,4PKDQ@976|Bacteroidetes,47Y9R@768503|Cytophagia 976|Bacteroidetes I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 CMS3_k127_3036932_0 1121904.ARBP01000042_gene4905 4.844e-259 814.0 COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop CMS3_k127_3048751_3 694427.Palpr_1669 5.202e-60 211.0 COG1028@1|root,COG1028@2|Bacteria,4NHSE@976|Bacteroidetes,2G33D@200643|Bacteroidia 976|Bacteroidetes IQ Oxidoreductase, short chain dehydrogenase reductase family protein - - - - - - - - - - - - adh_short CMS3_k127_3048751_0 1122176.KB903554_gene3963 0.0 1127.0 COG1529@1|root,COG1529@2|Bacteria,4NERZ@976|Bacteroidetes 976|Bacteroidetes C Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_3048751_1 1122176.KB903554_gene3964 5.25e-82 275.0 COG2080@1|root,COG2080@2|Bacteria,4NMPX@976|Bacteroidetes 976|Bacteroidetes C Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_3048751_2 1122176.KB903554_gene3965 5.494e-61 212.0 29NNR@1|root,309KP@2|Bacteria,4NMF1@976|Bacteroidetes,1IRMU@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3049434_0 886293.Sinac_0388 1.204e-93 318.0 COG1621@1|root,COG1621@2|Bacteria,2IZ2Q@203682|Planctomycetes 203682|Planctomycetes G beta-fructofuranosidase activity - - - - - - - - - - - - - CMS3_k127_3049434_1 1233950.IW22_06885 3.768e-45 179.0 COG2159@1|root,COG2159@2|Bacteria,4P1C7@976|Bacteroidetes,1IIED@117743|Flavobacteriia 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_3049434_2 1122176.KB903554_gene3912 9.754e-15 76.0 COG1672@1|root,COG1672@2|Bacteria,4NR06@976|Bacteroidetes 976|Bacteroidetes L Leucine-rich repeat (LRR) protein - - - - - - - - - - - - AAA_16 CMS3_k127_3061180_0 1122176.KB903550_gene4317 1.172e-116 383.0 COG0131@1|root,COG0241@1|root,COG0131@2|Bacteria,COG0241@2|Bacteria,4NENP@976|Bacteroidetes,1IP4B@117747|Sphingobacteriia 976|Bacteroidetes E belongs to the imidazoleglycerol-phosphate dehydratase family hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_like,IGPD,PNK3P CMS3_k127_3061180_6 760192.Halhy_3315 6.332e-58 207.0 COG1418@1|root,COG1418@2|Bacteria,4NFAG@976|Bacteroidetes,1ISTR@117747|Sphingobacteriia 976|Bacteroidetes S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - - - - - - - - - - Guanylate_cyc,HD CMS3_k127_3061180_4 929713.NIASO_06295 1.557e-79 269.0 COG0118@1|root,COG0118@2|Bacteria,4NF4J@976|Bacteroidetes,1IT1P@117747|Sphingobacteriia 976|Bacteroidetes E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase CMS3_k127_3061180_3 319236.JCM19294_1277 5.442e-83 283.0 COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1HWQ2@117743|Flavobacteriia,3HJK4@363408|Nonlabens 976|Bacteroidetes E Histidine biosynthesis protein hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS3_k127_3061180_1 504472.Slin_5537 4.714e-110 360.0 COG0107@1|root,COG0107@2|Bacteria,4NE16@976|Bacteroidetes,47K9T@768503|Cytophagia 976|Bacteroidetes E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS3_k127_3061180_5 926556.Echvi_2517 6.756e-76 259.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,4NERE@976|Bacteroidetes,47KYT@768503|Cytophagia 976|Bacteroidetes E Belongs to the PRA-CH family hisI - 3.5.4.19,3.6.1.31 ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH,PRA-PH CMS3_k127_3061180_2 313606.M23134_01624 1.191e-95 316.0 COG1216@1|root,COG1216@2|Bacteria,4NEHI@976|Bacteroidetes,47JE4@768503|Cytophagia 976|Bacteroidetes S PFAM Glycosyl transferase family 2 dpm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 CMS3_k127_3061980_0 760192.Halhy_1472 0.0 1528.0 COG1629@1|root,COG1629@2|Bacteria,4PKAS@976|Bacteroidetes,1IPMG@117747|Sphingobacteriia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3061980_1 880070.Cycma_2963 5.461e-39 155.0 COG3712@1|root,COG3712@2|Bacteria,4NQUV@976|Bacteroidetes,47QCF@768503|Cytophagia 976|Bacteroidetes PT PFAM FecR protein - - - - - - - - - - - - DUF4974,FecR CMS3_k127_307194_1 1443665.JACA01000042_gene1690 9.762e-172 548.0 COG1396@1|root,COG1680@1|root,COG3296@1|root,COG1396@2|Bacteria,COG1680@2|Bacteria,COG3296@2|Bacteria,4NG6Z@976|Bacteroidetes,1HZC5@117743|Flavobacteriia,2YJ2N@290174|Aquimarina 976|Bacteroidetes KV Beta-lactamase - - - - - - - - - - - - Beta-lactamase,DUF4870,HTH_3 CMS3_k127_307194_4 1120965.AUBV01000003_gene442 1.428e-34 136.0 COG2259@1|root,COG2259@2|Bacteria,4NSBJ@976|Bacteroidetes,47SCA@768503|Cytophagia 976|Bacteroidetes S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX CMS3_k127_307194_3 1122225.AULQ01000005_gene2642 4.508e-58 205.0 COG1764@1|root,COG1764@2|Bacteria,4NQKB@976|Bacteroidetes,1I2YF@117743|Flavobacteriia 976|Bacteroidetes O Peroxiredoxin osmC - - ko:K04063 - - - - ko00000 - - - OsmC CMS3_k127_307194_2 1089547.KB913013_gene4031 2.838e-104 347.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHMI@976|Bacteroidetes,47K6B@768503|Cytophagia 976|Bacteroidetes CG Membrane-bound dehydrogenase domain protein - - - - - - - - - - - - Cytochrom_C,HEAT_2,PmoA CMS3_k127_307194_0 1185876.BN8_01964 2.461e-224 702.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHMI@976|Bacteroidetes,47K6B@768503|Cytophagia 976|Bacteroidetes CG Membrane-bound dehydrogenase domain protein - - - - - - - - - - - - Cytochrom_C,HEAT_2,PmoA CMS3_k127_308194_5 1123035.ARLA01000021_gene897 2.335e-62 218.0 COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia,4C2HX@83612|Psychroflexus 976|Bacteroidetes C Pyridine nucleotide-disulphide oxidoreductase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS3_k127_308194_3 1121481.AUAS01000014_gene2315 1.005e-87 302.0 COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,47KY6@768503|Cytophagia 976|Bacteroidetes C PFAM 2Fe-2S iron-sulfur cluster binding domain dmpP - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 CMS3_k127_308194_10 700598.Niako_5113 3.512e-26 119.0 COG2885@1|root,COG2885@2|Bacteria,4NIV8@976|Bacteroidetes,1IXGD@117747|Sphingobacteriia 976|Bacteroidetes M OmpA MotB domain protein - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA CMS3_k127_308194_11 926549.KI421517_gene384 3.417e-20 98.0 COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH CMS3_k127_308194_12 1227739.Hsw_0348 4.354e-19 94.0 COG2825@1|root,COG2825@2|Bacteria,4NQHJ@976|Bacteroidetes,47QWE@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane protein (OmpH-like) ompH - - ko:K06142 - - - - ko00000 - - - OmpH CMS3_k127_308194_9 926549.KI421517_gene385 1.604e-40 156.0 COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,47PD1@768503|Cytophagia 976|Bacteroidetes M PFAM Outer membrane protein (OmpH-like) skp - - ko:K06142 - - - - ko00000 - - - OmpH CMS3_k127_308194_0 880071.Fleli_1549 1.368e-234 751.0 COG4775@1|root,COG4775@2|Bacteria,4NE6Z@976|Bacteroidetes,47JEC@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein assembly complex, YaeT protein yaeT - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA CMS3_k127_308194_1 1150600.ADIARSV_0572 7.004e-102 338.0 COG0020@1|root,COG0020@2|Bacteria,4NF2B@976|Bacteroidetes,1IPRJ@117747|Sphingobacteriia 976|Bacteroidetes I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf CMS3_k127_308194_8 926549.KI421517_gene389 5.145e-42 166.0 COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,47M42@768503|Cytophagia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl CMS3_k127_308194_4 929556.Solca_0559 9.18e-76 265.0 COG0061@1|root,COG0061@2|Bacteria,4NFG5@976|Bacteroidetes,1IPBF@117747|Sphingobacteriia 976|Bacteroidetes G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase CMS3_k127_308194_7 1120968.AUBX01000013_gene3458 3.143e-47 188.0 COG4775@1|root,COG4775@2|Bacteria,4NF9Y@976|Bacteroidetes,47KUK@768503|Cytophagia 976|Bacteroidetes M PFAM surface antigen variable number repeat - - - - - - - - - - - - Bac_surface_Ag,POTRA CMS3_k127_308194_6 385682.AFSL01000041_gene275 9.978e-48 179.0 COG0517@1|root,COG0517@2|Bacteria,4NF8G@976|Bacteroidetes,2FT2B@200643|Bacteroidia,3XIWD@558415|Marinilabiliaceae 976|Bacteroidetes S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS CMS3_k127_308194_2 1237149.C900_02728 1.937e-95 318.0 COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,47KEX@768503|Cytophagia 976|Bacteroidetes I alpha/beta hydrolase fold pcbD - - - - - - - - - - - Abhydrolase_1 CMS3_k127_3091644_3 926549.KI421517_gene2445 3.586e-84 284.0 COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47MIQ@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_3091644_4 1121931.AUHG01000011_gene2159 4.352e-30 131.0 COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,1HXZS@117743|Flavobacteriia 976|Bacteroidetes M Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - Fasciclin CMS3_k127_3091644_2 997296.PB1_11979 1.951e-121 396.0 COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,1ZBD0@1386|Bacillus 91061|Bacilli S Carbon-nitrogen hydrolase - - 3.5.5.1 ko:K01501 ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120 - R00540,R01887,R03093,R03542,R05591,R07855 RC00315,RC00325,RC00617,RC00959,RC02811 ko00000,ko00001,ko01000 - - - CN_hydrolase CMS3_k127_3091644_1 468059.AUHA01000004_gene2310 9.278e-205 658.0 COG2366@1|root,COG2366@2|Bacteria,4NGXQ@976|Bacteroidetes,1ISP6@117747|Sphingobacteriia 976|Bacteroidetes S COG2366 Protein related to penicillin acylase - - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase CMS3_k127_3091644_0 1121904.ARBP01000017_gene5125 2.315e-236 751.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes 1121904.ARBP01000017_gene5125|- C Planctomycete cytochrome C - - - - - - - - - - - - - CMS3_k127_3095934_5 1189612.A33Q_2982 4.437e-22 100.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47U4M@768503|Cytophagia 976|Bacteroidetes G Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_3095934_1 1336208.JADY01000025_gene2445 5.122e-52 196.0 COG0329@1|root,COG0329@2|Bacteria,1MWAH@1224|Proteobacteria,2TSXX@28211|Alphaproteobacteria,2JS0U@204441|Rhodospirillales 204441|Rhodospirillales EM Dihydrodipicolinate synthetase family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS3_k127_3095934_3 760192.Halhy_5421 1.54e-35 140.0 297Z5@1|root,2ZV5A@2|Bacteria,4NPFS@976|Bacteroidetes,1IUP6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3095934_2 1313421.JHBV01000046_gene259 6.024e-44 166.0 2DZK1@1|root,32VCS@2|Bacteria,4NTZ5@976|Bacteroidetes,1ITPD@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3095934_0 1121889.AUDM01000008_gene843 9.705e-167 537.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1I6TA@117743|Flavobacteriia 976|Bacteroidetes S ATPase domain predominantly from Archaea - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_3095934_4 945713.IALB_1795 8.753e-28 119.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HTH_18,Pkinase,TPR_19,TPR_2,TPR_8 CMS3_k127_3103019_2 530564.Psta_1511 8.359e-89 297.0 COG4946@1|root,COG4946@2|Bacteria,2IY4Z@203682|Planctomycetes 203682|Planctomycetes M arylsulfatase activity - - - - - - - - - - - - - CMS3_k127_3103019_1 595460.RRSWK_04098 1.06e-95 326.0 COG3119@1|root,COG4946@1|root,COG3119@2|Bacteria,COG4946@2|Bacteria,2IY4Z@203682|Planctomycetes 203682|Planctomycetes M arylsulfatase activity - - - - - - - - - - - - - CMS3_k127_3103019_3 1121904.ARBP01000033_gene3193 9.795e-59 210.0 COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia 976|Bacteroidetes S PFAM phospholipase Carboxylesterase - - - - - - - - - - - - Abhydrolase_2,FSH1 CMS3_k127_3103019_0 1047013.AQSP01000092_gene315 3.145e-290 924.0 COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolases family 2, TIM barrel domain lacZ GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23,3.2.1.31 ko:K01190,ko:K01195 ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830 RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CMS3_k127_3103019_4 929703.KE386491_gene2588 3.933e-44 164.0 COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47JWP@768503|Cytophagia 976|Bacteroidetes IQ KR domain - - 1.1.1.53 ko:K00038 ko00140,ko01100,map00140,map01100 - R04831,R04834,R04844,R04847 RC00139,RC01219,RC01220 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 CMS3_k127_3112577_1 459349.CLOAM0985 6.89e-09 61.0 COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria 2|Bacteria M FlgD Ig-like domain - - - - - - - - - - - - CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25 CMS3_k127_3112577_2 1123278.KB893592_gene6008 0.0003525 44.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47Y22@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_3112577_0 1121904.ARBP01000009_gene4223 5.387e-49 179.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,4NF1F@976|Bacteroidetes,47MSJ@768503|Cytophagia 976|Bacteroidetes T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg CMS3_k127_311751_0 1121373.KB903620_gene2082 4.495e-103 343.0 COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,47M96@768503|Cytophagia 976|Bacteroidetes G Glycogen debranching enzyme - - - - - - - - - - - - GDE_C,GDE_N CMS3_k127_311751_1 760192.Halhy_4392 1.139e-27 131.0 COG4995@1|root,COG5635@1|root,COG4995@2|Bacteria,COG5635@2|Bacteria,4NSQS@976|Bacteroidetes,1IZNP@117747|Sphingobacteriia 976|Bacteroidetes T Nacht domain - - - - - - - - - - - - NACHT,TIR_2 CMS3_k127_3123745_3 1433126.BN938_2795 1.141e-14 75.0 COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,2G07R@200643|Bacteroidia 976|Bacteroidetes P Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family xylE - - ko:K02100,ko:K03444,ko:K08138 - - - - ko00000,ko02000 2.A.1.1,2.A.1.1.2,2.A.1.1.3 - - Sugar_tr CMS3_k127_3123745_1 1250006.JHZZ01000001_gene2391 6.534e-211 666.0 COG0702@1|root,COG0702@2|Bacteria,4NJQQ@976|Bacteroidetes,1HZMF@117743|Flavobacteriia 976|Bacteroidetes GM SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_3123745_0 1250006.JHZZ01000001_gene2392 0.0 1238.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia 976|Bacteroidetes P Outer membrane receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3123745_2 1349785.BAUG01000048_gene2351 2.276e-46 181.0 COG3712@1|root,COG3712@2|Bacteria,4NQUV@976|Bacteroidetes,1I1HJ@117743|Flavobacteriia 976|Bacteroidetes PT Domain of unknown function (DUF4974) - - - - - - - - - - - - DUF4974,FecR CMS3_k127_3125267_2 1237149.C900_03362 0.0004424 45.0 COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia 976|Bacteroidetes S FixH ccoH - - ko:K09926 - - - - ko00000 - - - FixH CMS3_k127_3125267_0 643867.Ftrac_1619 4.379e-166 534.0 COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,47KT1@768503|Cytophagia 976|Bacteroidetes C TIGRFAM cytochrome c oxidase accessory protein ccoG - - - - - - - - - - - Fer4_18,Fer4_5,FixG_C CMS3_k127_3125267_1 1121904.ARBP01000002_gene7144 1.743e-71 248.0 COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,47PY8@768503|Cytophagia 976|Bacteroidetes C TIGRFAM cytochrome c oxidase, cbb3-type, subunit III ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N CMS3_k127_3134322_1 1121904.ARBP01000014_gene133 5.177e-115 388.0 COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,4NI4S@976|Bacteroidetes,47M53@768503|Cytophagia 976|Bacteroidetes CL Protein of unknown function (DUF1595) - - - - - - - - - - - - PSCyt3,PSD2,PSD3,PSD4,PSD5 CMS3_k127_3134322_2 760192.Halhy_6239 3.41e-84 284.0 COG0745@1|root,COG0745@2|Bacteria,4NMAC@976|Bacteroidetes,1J08E@117747|Sphingobacteriia 976|Bacteroidetes T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_3134322_4 760192.Halhy_6240 8.523e-68 246.0 COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_3134322_3 1123248.KB893326_gene1452 2.734e-80 276.0 COG1082@1|root,COG1082@2|Bacteria,4NFMD@976|Bacteroidetes,1IVV3@117747|Sphingobacteriia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_3134322_0 1121875.KB907550_gene790 7.627e-281 876.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,1HX7C@117743|Flavobacteriia 976|Bacteroidetes C PFAM Cytochrome C - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2 CMS3_k127_3140388_4 1121904.ARBP01000007_gene2906 4.928e-39 154.0 COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes 976|Bacteroidetes O Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - CMS3_k127_3140388_0 1121129.KB903359_gene1255 1.305e-99 335.0 COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,22XC0@171551|Porphyromonadaceae 976|Bacteroidetes S Von Willebrand factor type A domain batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA CMS3_k127_3140388_2 1121904.ARBP01000007_gene2909 2.706e-86 297.0 COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia 2|Bacteria S PFAM von Willebrand factor type A batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 CMS3_k127_3140388_6 1121904.ARBP01000007_gene2910 2.218e-28 123.0 COG0457@1|root,COG0457@2|Bacteria,4NH2K@976|Bacteroidetes 976|Bacteroidetes M tetratricopeptide repeat batC - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 CMS3_k127_3140388_1 1236514.BAKL01000060_gene4056 4.239e-94 333.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,4AK7T@815|Bacteroidaceae 976|Bacteroidetes S COG NOG06393 non supervised orthologous group batD - - - - - - - - - - - BatD,TPR_2 CMS3_k127_3140388_3 869213.JCM21142_3977 2.234e-42 165.0 COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes 976|Bacteroidetes T tetratricopeptide repeat batE - - - - - - - - - - - SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2 CMS3_k127_3140388_5 1121904.ARBP01000007_gene2999 2.633e-31 136.0 2FI0F@1|root,349TD@2|Bacteria,4P6FQ@976|Bacteroidetes,47W7E@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3142988_1 51453.EGR50114 1.723e-09 70.0 KOG0266@1|root,KOG0295@1|root,KOG0266@2759|Eukaryota,KOG0295@2759|Eukaryota,38B6D@33154|Opisthokonta,3NYUK@4751|Fungi,3QPYU@4890|Ascomycota,212WB@147550|Sordariomycetes,3TJMB@5125|Hypocreales 4751|Fungi D Conserved hypothetical protein - - - - - - - - - - - - NACHT,NACHT_N,WD40 CMS3_k127_3142988_0 1239962.C943_00590 1.996e-280 876.0 COG0556@1|root,COG0556@2|Bacteria,4NE6E@976|Bacteroidetes,47KBV@768503|Cytophagia 976|Bacteroidetes L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB CMS3_k127_3144763_0 880070.Cycma_3293 5.406e-107 372.0 COG1196@1|root,COG4995@1|root,COG1196@2|Bacteria,COG4995@2|Bacteria,4NMDK@976|Bacteroidetes 976|Bacteroidetes D Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_3144763_1 696747.NIES39_J02400 0.0006531 53.0 COG3118@1|root,COG4995@1|root,COG3118@2|Bacteria,COG4995@2|Bacteria,1G18G@1117|Cyanobacteria,1H83U@1150|Oscillatoriales 1117|Cyanobacteria O Tetratricopeptide repeat domain protein hetF - - - - - - - - - - - CHAT CMS3_k127_3145136_1 153721.MYP_2257 9.045e-34 132.0 COG2030@1|root,COG2030@2|Bacteria,4NPYH@976|Bacteroidetes,47PSF@768503|Cytophagia 976|Bacteroidetes I MaoC domain protein dehydratase maoC - 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydratas CMS3_k127_3145136_0 518766.Rmar_0465 3.686e-120 398.0 COG0686@1|root,COG0686@2|Bacteria,4NE8F@976|Bacteroidetes,1FIM6@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Alanine dehydrogenase/PNT, N-terminal domain ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N CMS3_k127_3145136_2 1538644.KO02_01765 9.005e-17 81.0 COG0802@1|root,COG0802@2|Bacteria,4NS89@976|Bacteroidetes,1ISTA@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Uncharacterised protein family UPF0079, ATPase yjeE - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE CMS3_k127_3150958_2 517418.Ctha_0561 6.525e-44 168.0 COG4636@1|root,COG4636@2|Bacteria,1FFDX@1090|Chlorobi 1090|Chlorobi S Putative restriction endonuclease - - - - - - - - - - - - Uma2 CMS3_k127_3150958_1 1121904.ARBP01000001_gene5778 3.249e-51 199.0 COG0739@1|root,COG4219@1|root,COG0739@2|Bacteria,COG4219@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23,Peptidase_M56 CMS3_k127_3150958_3 1121904.ARBP01000001_gene5779 1.059e-43 162.0 COG3682@1|root,COG3682@2|Bacteria,4NNVM@976|Bacteroidetes,47Q5Z@768503|Cytophagia 976|Bacteroidetes K PFAM Penicillinase repressor - - - - - - - - - - - - Penicillinase_R CMS3_k127_3150958_0 391596.PBAL39_02197 9.261e-83 285.0 COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,1IPNC@117747|Sphingobacteriia 976|Bacteroidetes P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N CMS3_k127_315397_0 880070.Cycma_4697 2.337e-209 661.0 COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47MR5@768503|Cytophagia 976|Bacteroidetes E RagB SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_3161863_0 946077.W5A_09647 3.895e-189 627.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1I04A@117743|Flavobacteriia 976|Bacteroidetes P Outer membrane receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_3161863_1 1121912.AUHD01000005_gene1577 1.125e-42 167.0 COG3193@1|root,COG3193@2|Bacteria,4NI6Y@976|Bacteroidetes,1HXJ0@117743|Flavobacteriia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_3162145_0 880071.Fleli_0762 2.457e-125 406.0 COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,47JMY@768503|Cytophagia 976|Bacteroidetes Q TIGRFAM phytoene desaturase crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase CMS3_k127_3162145_1 3218.PP1S180_110V6.1 1.228e-124 405.0 COG0115@1|root,KOG0975@2759|Eukaryota,37P5K@33090|Viridiplantae,3G79E@35493|Streptophyta 35493|Streptophyta E branched-chain-amino-acid aminotransferase-like protein - - - - - - - - - - - - Aminotran_4,Methyltransf_16 CMS3_k127_3162145_4 1121904.ARBP01000001_gene5888 2.266e-66 235.0 COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47S6X@768503|Cytophagia 976|Bacteroidetes M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race CMS3_k127_3162145_9 1121288.AULL01000012_gene225 2.64e-05 58.0 COG4886@1|root,COG4886@2|Bacteria 2|Bacteria S regulation of response to stimulus - - - ko:K15354 ko05132,map05132 - - - ko00000,ko00001 - - - Big_2,LRR_5 CMS3_k127_3162145_8 1122176.KB903609_gene5228 1.278e-38 167.0 COG1404@1|root,COG2374@1|root,COG4412@1|root,COG1404@2|Bacteria,COG2374@2|Bacteria,COG4412@2|Bacteria,4NTJJ@976|Bacteroidetes 976|Bacteroidetes O Lamin Tail Domain - - - - - - - - - - - - LTD CMS3_k127_3162145_6 502025.Hoch_5031 1.568e-53 215.0 COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,438DH@68525|delta/epsilon subdivisions,2WXQW@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Endonuclease/Exonuclease/phosphatase family - - - ko:K07004 - - - - ko00000 - - - Exo_endo_phos CMS3_k127_3162145_2 1128421.JAGA01000002_gene861 2.846e-102 340.0 COG2897@1|root,COG2897@2|Bacteria,2NQJ4@2323|unclassified Bacteria 2|Bacteria P Rhodanese Homology Domain sseA - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese CMS3_k127_3162145_3 649638.Trad_0396 1.067e-72 253.0 2C3PP@1|root,2Z954@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_3162145_5 1121904.ARBP01000015_gene156 1.78e-58 221.0 COG0457@1|root,COG0457@2|Bacteria,4P1W8@976|Bacteroidetes,47TEF@768503|Cytophagia 976|Bacteroidetes S TPR repeat - - - - - - - - - - - - TPR_16,TPR_8 CMS3_k127_3162145_7 926549.KI421517_gene3485 1.508e-40 153.0 COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,47JXG@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b CMS3_k127_3163209_0 1121904.ARBP01000002_gene6846 2.524e-269 843.0 COG5434@1|root,COG5434@2|Bacteria,4NG62@976|Bacteroidetes,47TF7@768503|Cytophagia 976|Bacteroidetes M Heparinase II/III N-terminus - - - - - - - - - - - - Alginate_lyase,Beta_helix,Hepar_II_III,Hepar_II_III_N CMS3_k127_3163209_1 926556.Echvi_1130 5.259e-200 631.0 COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,47KJR@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,TAT_signal CMS3_k127_3173125_1 1121904.ARBP01000002_gene6922 1.867e-20 106.0 COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NJZ8@976|Bacteroidetes,47X9Q@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,WD40 CMS3_k127_3173125_0 309799.DICTH_0238 2.047e-74 271.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - DUF5122 CMS3_k127_3173125_2 1121904.ARBP01000005_gene4597 4.099e-09 67.0 2DBNY@1|root,2ZA6F@2|Bacteria,4NH2P@976|Bacteroidetes,47X5R@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3176991_4 1123277.KB893187_gene2724 7.182e-62 235.0 COG1629@1|root,COG3078@1|root,COG3078@2|Bacteria,COG4771@2|Bacteria,4NIGK@976|Bacteroidetes,47K8U@768503|Cytophagia 976|Bacteroidetes P GTPase activator activity - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_3176991_5 485913.Krac_6225 9.501e-36 142.0 COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi 200795|Chloroflexi Q PFAM Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_31 CMS3_k127_3176991_0 1122176.KB903532_gene2573 3.713e-160 516.0 COG0534@1|root,COG0534@2|Bacteria,4NDUF@976|Bacteroidetes 976|Bacteroidetes V Mate efflux family protein - - - - - - - - - - - - MatE CMS3_k127_3176991_3 1168034.FH5T_14930 3.203e-83 286.0 COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,2FX9X@200643|Bacteroidia 976|Bacteroidetes M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel CMS3_k127_3176991_2 1237149.C900_03099 7.656e-109 356.0 COG0745@1|root,COG0745@2|Bacteria,4NGI5@976|Bacteroidetes,47NIM@768503|Cytophagia 976|Bacteroidetes T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_3176991_1 1237149.C900_03098 6.406e-138 452.0 COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,47NRA@768503|Cytophagia 976|Bacteroidetes T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA CMS3_k127_3177576_0 1453500.AT05_09370 1.933e-306 965.0 COG1629@1|root,COG4771@2|Bacteria 2|Bacteria P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec CMS3_k127_3177576_3 485918.Cpin_6314 1.88e-08 61.0 2DM52@1|root,32UG7@2|Bacteria,4NSYJ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - Lipocalin_4 CMS3_k127_3177576_1 760192.Halhy_2292 1.619e-159 519.0 COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,1IRN9@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Peptidase M1 membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,Peptidase_M1 CMS3_k127_3177576_4 234621.RER_41370 3.559e-07 58.0 COG3832@1|root,COG3832@2|Bacteria,2I51C@201174|Actinobacteria,4G1H4@85025|Nocardiaceae 201174|Actinobacteria K Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 CMS3_k127_3177576_2 1077285.AGDG01000039_gene4043 7.859e-09 57.0 COG2227@1|root,COG2227@2|Bacteria,4PKW0@976|Bacteroidetes,2FNGZ@200643|Bacteroidia,4AKXP@815|Bacteroidaceae 976|Bacteroidetes H Methyltransferase domain protein cypM_1 - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 CMS3_k127_3193754_2 1121904.ARBP01000003_gene6273 2.777e-129 426.0 28K6N@1|root,2Z9V2@2|Bacteria,4NKJ8@976|Bacteroidetes,47TQ1@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3193754_3 1296415.JACC01000032_gene650 1.009e-116 381.0 COG2819@1|root,COG2819@2|Bacteria,4NGAG@976|Bacteroidetes,1HZR3@117743|Flavobacteriia,2YKNA@290174|Aquimarina 976|Bacteroidetes S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase CMS3_k127_3193754_1 313596.RB2501_11927 2.862e-132 432.0 COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,1I0ZH@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_3193754_4 1461577.CCMH01000009_gene1578 7.364e-57 206.0 COG0299@1|root,COG0299@2|Bacteria,4PP54@976|Bacteroidetes,1I6H5@117743|Flavobacteriia 976|Bacteroidetes F Formyl transferase - - - - - - - - - - - - Formyl_trans_N CMS3_k127_3193754_0 1122179.KB890431_gene4241 1.124e-278 863.0 COG4805@1|root,COG4805@2|Bacteria,4NK1Q@976|Bacteroidetes 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - - CMS3_k127_3202423_5 1238450.VIBNISOn1_1720059 1.478e-20 102.0 COG0741@1|root,COG0741@2|Bacteria,1RH42@1224|Proteobacteria,1S92N@1236|Gammaproteobacteria,1XXMA@135623|Vibrionales 135623|Vibrionales M lytic transglycosylase activity - - - - - - - - - - - - SLT CMS3_k127_3202423_1 1124780.ANNU01000015_gene2010 2.057e-137 445.0 COG1533@1|root,COG1533@2|Bacteria,4NE62@976|Bacteroidetes,47M4W@768503|Cytophagia 976|Bacteroidetes L SMART Elongator protein 3 MiaB NifB - - - - - - - - - - - - Radical_SAM CMS3_k127_3202423_2 929556.Solca_0376 1.949e-134 436.0 COG2021@1|root,COG2021@2|Bacteria,4NFG2@976|Bacteroidetes,1IQEA@117747|Sphingobacteriia 976|Bacteroidetes E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metXA - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS3_k127_3202423_0 929556.Solca_0377 1.038e-213 670.0 COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1IPSV@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_3202423_3 926562.Oweho_2044 1.29e-30 140.0 2EW37@1|root,33PGF@2|Bacteria,4P22D@976|Bacteroidetes,1I7PK@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3202423_4 1313421.JHBV01000069_gene4635 2.124e-25 123.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,CHU_C,Gram_pos_anchor,SprB,TIG CMS3_k127_3213343_2 1123277.KB893174_gene6004 9.722e-40 149.0 COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes,47K5G@768503|Cytophagia 976|Bacteroidetes G BNR repeat-like domain - - 3.2.1.40 ko:K05989 - - - - ko00000,ko01000 - - - BNR_2,Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N CMS3_k127_3213343_1 761193.Runsl_0035 2.218e-86 296.0 COG0546@1|root,COG2870@1|root,COG0546@2|Bacteria,COG2870@2|Bacteria,4NJ8F@976|Bacteroidetes,47MRA@768503|Cytophagia 976|Bacteroidetes M pfkB family carbohydrate kinase - - - - - - - - - - - - Hydrolase,PfkB CMS3_k127_3213343_0 1123277.KB893217_gene4619 2.663e-199 628.0 COG2942@1|root,COG2942@2|Bacteria,4NHTQ@976|Bacteroidetes,47KVQ@768503|Cytophagia 976|Bacteroidetes G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - 5.1.3.11 ko:K16213 - - R01445,R10810 RC00289 ko00000,ko01000 - - - GlcNAc_2-epim CMS3_k127_3213343_3 1121904.ARBP01000001_gene5605 3.506e-22 101.0 COG2207@1|root,COG2207@2|Bacteria,4PMN6@976|Bacteroidetes 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - DUF1835 CMS3_k127_3213960_0 1121904.ARBP01000002_gene7062 2.971e-267 838.0 COG3206@1|root,COG3206@2|Bacteria,4NH33@976|Bacteroidetes 976|Bacteroidetes M regulator of chromosome condensation, RCC1 - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_3213960_1 1288963.ADIS_4337 1.612e-17 86.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47M4N@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 CMS3_k127_3214022_1 1305737.JAFX01000001_gene1692 1.185e-122 405.0 COG1373@1|root,COG1373@2|Bacteria,4NE3E@976|Bacteroidetes,47P2P@768503|Cytophagia 976|Bacteroidetes S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14 CMS3_k127_3214022_3 1408813.AYMG01000013_gene1260 1.976e-09 70.0 COG1020@1|root,COG1020@2|Bacteria,4NGQI@976|Bacteroidetes,1IVZG@117747|Sphingobacteriia 976|Bacteroidetes Q Condensation domain - - - - - - - - - - - - AATase,Condensation CMS3_k127_3214022_2 313606.M23134_02278 2.924e-69 256.0 COG3386@1|root,COG3405@1|root,COG3386@2|Bacteria,COG3405@2|Bacteria,4PM1B@976|Bacteroidetes,47XZC@768503|Cytophagia 976|Bacteroidetes G SPTR Cell surface protein - - - - - - - - - - - - - CMS3_k127_3214022_0 313606.M23134_02904 1.382e-245 762.0 COG1032@1|root,COG1032@2|Bacteria,4NGYA@976|Bacteroidetes,47JD7@768503|Cytophagia 976|Bacteroidetes C Domain of unknown function (DUF3362) - - - - - - - - - - - - DUF3362,Radical_SAM,Radical_SAM_N CMS3_k127_3216670_0 1313301.AUGC01000008_gene386 2.477e-210 658.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes 976|Bacteroidetes E Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_3216670_4 1547437.LL06_03270 8.527e-23 108.0 COG0741@1|root,COG0741@2|Bacteria,1RH42@1224|Proteobacteria,2UST0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - SLT CMS3_k127_3216670_5 866536.Belba_2334 1.269e-12 78.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes 976|Bacteroidetes T universal stress protein uspA - - - - - - - - - - - DUF2007,Usp CMS3_k127_3216670_2 1237149.C900_00900 2.699e-132 425.0 COG0247@1|root,COG0247@2|Bacteria,4NDZS@976|Bacteroidetes,47KRT@768503|Cytophagia 976|Bacteroidetes C PFAM Cysteine-rich domain - - - - - - - - - - - - CCG CMS3_k127_3216670_1 1408433.JHXV01000005_gene2529 3.023e-163 528.0 COG0247@1|root,COG0247@2|Bacteria,4PM9R@976|Bacteroidetes,1IJNY@117743|Flavobacteriia,2PACW@246874|Cryomorphaceae 976|Bacteroidetes C 4Fe-4S dicluster domain - - - - - - - - - - - - Fer4_8,Fer4_9 CMS3_k127_3216670_3 1239962.C943_02211 1.838e-128 425.0 COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,47JA4@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 - - - ko00000,ko00001,ko02000 2.A.21,2.A.21.8 - - HD_4,SSF CMS3_k127_3224106_2 269798.CHU_3265 7.216e-71 262.0 2C4MF@1|root,300D5@2|Bacteria,4NPEA@976|Bacteroidetes,47RYT@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3224106_4 762984.HMPREF9445_00883 5.168e-06 59.0 COG1629@1|root,COG4771@2|Bacteria,4NJV0@976|Bacteroidetes,2FNMY@200643|Bacteroidia,4AMGJ@815|Bacteroidaceae 976|Bacteroidetes P Psort location OuterMembrane, score - - - - - - - - - - - - - CMS3_k127_3224106_0 1124780.ANNU01000018_gene1648 2.025e-188 598.0 COG0044@1|root,COG0044@2|Bacteria,4NE3T@976|Bacteroidetes,47JPG@768503|Cytophagia 976|Bacteroidetes F TIGRFAM dihydroorotase, multifunctional complex type pyrC - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 CMS3_k127_3224106_1 1123057.P872_04615 6.69e-84 284.0 COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,47P9Q@768503|Cytophagia 976|Bacteroidetes F deoxynucleoside kinase dck - - - - - - - - - - - dNK CMS3_k127_3224106_3 926560.KE387023_gene2413 1.131e-45 177.0 COG2936@1|root,COG2936@2|Bacteria,1WN5B@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - - - - - - - - - - PepX_C,Peptidase_S15 CMS3_k127_3233034_0 1408473.JHXO01000001_gene2036 2.292e-181 581.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,2FS4M@200643|Bacteroidia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_3233034_1 760192.Halhy_3609 4.236e-166 533.0 COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1IQ5B@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_3238507_4 760192.Halhy_3670 1.573e-148 474.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,4NM18@976|Bacteroidetes,1INYM@117747|Sphingobacteriia 976|Bacteroidetes C COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase - - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2 CMS3_k127_3238507_1 760192.Halhy_3671 3.425e-281 875.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1IYHV@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Pyruvate flavodoxin ferredoxin oxidoreductase - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N CMS3_k127_3238507_3 761193.Runsl_4910 1.254e-174 552.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,47KXJ@768503|Cytophagia 976|Bacteroidetes C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C CMS3_k127_3238507_0 761193.Runsl_5038 6.728e-294 922.0 COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47M6F@768503|Cytophagia 976|Bacteroidetes S Beta-L-arabinofuranosidase, GH127 - - - ko:K09955 - - - - ko00000 - - - F5_F8_type_C,Glyco_hydro_127 CMS3_k127_3238507_2 385682.AFSL01000089_gene918 3.458e-219 691.0 COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,2FN3P@200643|Bacteroidia,3XJHK@558415|Marinilabiliaceae 976|Bacteroidetes S Beta-L-arabinofuranosidase, GH127 - - - ko:K09955 - - - - ko00000 - - - DUF4986,Glyco_hydro_127 CMS3_k127_3243802_1 1122176.KB903541_gene273 2.863e-42 160.0 COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,1IYTE@117747|Sphingobacteriia 976|Bacteroidetes T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos CMS3_k127_3243802_0 1121904.ARBP01000004_gene1057 2.756e-168 540.0 COG1690@1|root,COG1690@2|Bacteria,4NG8T@976|Bacteroidetes,47N9X@768503|Cytophagia 976|Bacteroidetes S tRNA-splicing ligase RtcB rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB CMS3_k127_3244548_5 1111732.AZOD01000031_gene2025 1.831e-15 83.0 2AMM7@1|root,31CH8@2|Bacteria,1RJ8Y@1224|Proteobacteria,1SAP1@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Pyrimidine dimer DNA glycosylase denV - 3.1.25.1 ko:K01161 - - - - ko00000,ko01000 - - - Pyr_excise CMS3_k127_3244548_8 880070.Cycma_0078 8.419e-05 48.0 28WY4@1|root,2ZIX6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_3244548_0 313596.RB2501_01375 3.479e-158 510.0 COG1783@1|root,COG1783@2|Bacteria,4PMA2@976|Bacteroidetes,1I89P@117743|Flavobacteriia 976|Bacteroidetes S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C CMS3_k127_3244548_4 218284.CCDN010000001_gene888 2.083e-16 87.0 2DR9Y@1|root,33AUY@2|Bacteria,1UBBA@1239|Firmicutes,4IMQ7@91061|Bacilli,1ZKKS@1386|Bacillus 91061|Bacilli L HNH endonuclease - - - - - - - - - - - - HNH_3 CMS3_k127_3244548_7 720554.Clocl_1651 3.487e-05 52.0 COG1372@1|root,COG1372@2|Bacteria,1V120@1239|Firmicutes 1239|Firmicutes L SMART Hedgehog intein hint domain protein - - - - - - - - - - - - PT-HINT,WHH CMS3_k127_3244548_6 1144313.PMI10_00650 3.921e-13 75.0 COG1783@1|root,COG1783@2|Bacteria,4PMA2@976|Bacteroidetes,1I89P@117743|Flavobacteriia 976|Bacteroidetes S Phage terminase large subunit - - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C CMS3_k127_3244548_1 313596.RB2501_01380 2.982e-31 128.0 2BVDA@1|root,32QTA@2|Bacteria,4NV3V@976|Bacteroidetes 976|Bacteroidetes S DNA-packaging protein gp3 - - - - - - - - - - - - GP3_package CMS3_k127_3249336_1 1239962.C943_01243 1.769e-21 106.0 2F2KT@1|root,33VHI@2|Bacteria,4P2PT@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - DUF4230 CMS3_k127_3249336_0 980584.AFPB01000142_gene1246 1.891e-70 251.0 COG2334@1|root,COG2334@2|Bacteria,4NITA@976|Bacteroidetes 976|Bacteroidetes S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - - - - - - - - - - - CMS3_k127_3253009_2 929556.Solca_3798 5.494e-28 121.0 COG0457@1|root,COG0457@2|Bacteria,4NZVB@976|Bacteroidetes,1IVUF@117747|Sphingobacteriia 976|Bacteroidetes S Tetratricopeptide repeats - - - - - - - - - - - - TPR_16 CMS3_k127_3253009_3 1122176.KB903554_gene3913 5.136e-11 73.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_3253009_0 1121904.ARBP01000025_gene6097 1.489e-94 317.0 COG0491@1|root,COG0491@2|Bacteria,4NNDV@976|Bacteroidetes,47PUB@768503|Cytophagia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_3253009_4 984262.SGRA_3679 2.627e-10 70.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_3253009_5 80637.XP_007765987.1 0.0009145 52.0 2AHRJ@1|root,2RZ2Z@2759|Eukaryota,3A0Z7@33154|Opisthokonta,3P2N4@4751|Fungi,3V0NG@5204|Basidiomycota,2263F@155619|Agaricomycetes 4751|Fungi S Class I glutamine amidotransferase-like protein - - - - - - - - - - - - ThuA CMS3_k127_3253009_1 1185876.BN8_00772 7.287e-93 331.0 COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,47MNQ@768503|Cytophagia 976|Bacteroidetes O SprB repeat - - - - - - - - - - - - CHU_C,PKD,SprB,TIG CMS3_k127_3257824_1 926562.Oweho_3340 1.809e-59 213.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Metalloenzyme,Sulfatase CMS3_k127_3257824_0 888059.HMPREF9071_2376 2.12e-80 285.0 COG0507@1|root,COG0507@2|Bacteria,4NDYK@976|Bacteroidetes,1HWXU@117743|Flavobacteriia,1EQV2@1016|Capnocytophaga 976|Bacteroidetes L exodeoxyribonuclease V recD2_2 - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 CMS3_k127_3266409_0 926562.Oweho_3340 1.295e-50 183.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Metalloenzyme,Sulfatase CMS3_k127_3270105_1 523791.Kkor_2084 2.531e-50 181.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1XKKT@135619|Oceanospirillales 135619|Oceanospirillales M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL CMS3_k127_3270105_0 1270196.JCKI01000003_gene1989 3.424e-149 486.0 COG1508@1|root,COG1508@2|Bacteria,4NE5B@976|Bacteroidetes 976|Bacteroidetes K RNA polymerase, sigma-54 factor rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD CMS3_k127_327212_5 929704.Myrod_2777 3.675e-09 61.0 COG2755@1|root,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,1I0ZE@117743|Flavobacteriia,47HBK@76831|Myroides 976|Bacteroidetes EM GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2,LysM CMS3_k127_327212_1 643867.Ftrac_1843 2.526e-142 458.0 28H6T@1|root,2Z7J4@2|Bacteria,4NE4C@976|Bacteroidetes,47K71@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_327212_0 643867.Ftrac_0743 4.035e-158 511.0 COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,47U8Z@768503|Cytophagia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS3_k127_327212_3 742766.HMPREF9455_03004 5.697e-46 172.0 COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,2G2VX@200643|Bacteroidia,22XNA@171551|Porphyromonadaceae 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_327212_2 1122176.KB903550_gene4288 1.428e-101 339.0 28J46@1|root,2Z906@2|Bacteria,4NFYM@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF3078) - - - - - - - - - - - - DUF3078 CMS3_k127_327212_4 1150600.ADIARSV_1733 7.775e-46 169.0 COG0838@1|root,COG0838@2|Bacteria,4NQET@976|Bacteroidetes,1ISH2@117747|Sphingobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 CMS3_k127_3274757_0 1121904.ARBP01000010_gene2259 4.178e-208 653.0 COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase CMS3_k127_3274757_1 1121904.ARBP01000041_gene4964 8.683e-66 232.0 297E6@1|root,2ZUMN@2|Bacteria,4NPTI@976|Bacteroidetes,47R84@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_3274757_2 1168289.AJKI01000044_gene91 1.287e-45 172.0 COG1390@1|root,COG1390@2|Bacteria,4NTEY@976|Bacteroidetes,2G2KK@200643|Bacteroidia,3XJ25@558415|Marinilabiliaceae 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane - - - ko:K02121 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_B,vATP-synt_E CMS3_k127_3274757_3 869213.JCM21142_93432 1.679e-41 163.0 COG1527@1|root,COG1527@2|Bacteria,4NQJX@976|Bacteroidetes 976|Bacteroidetes C Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF2764 CMS3_k127_3285817_4 643867.Ftrac_0389 3.09e-25 108.0 COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia 976|Bacteroidetes S PFAM Membrane protein of yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 CMS3_k127_3285817_0 1121904.ARBP01000008_gene3414 0.0 1028.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47KVI@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 CMS3_k127_3285817_3 760192.Halhy_0717 7.039e-82 274.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,1IWSE@117747|Sphingobacteriia 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_3285817_1 344747.PM8797T_09164 3.125e-229 719.0 COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_3285817_2 1408473.JHXO01000007_gene986 1.648e-143 466.0 COG5492@1|root,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes 976|Bacteroidetes N Domain of unknown function (DUF5060) - - - - - - - - - - - - Collagen_bind_2,DUF5060 CMS3_k127_3298307_4 1122176.KB903537_gene1625 6.109e-46 168.0 COG2920@1|root,COG2920@2|Bacteria,4NSKM@976|Bacteroidetes,1J01M@117747|Sphingobacteriia 976|Bacteroidetes P DsrC like protein - - - ko:K11179 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - DsrC CMS3_k127_3298307_3 1122176.KB903537_gene1624 6.407e-82 274.0 COG2210@1|root,COG2210@2|Bacteria,4NNB9@976|Bacteroidetes,1IYG2@117747|Sphingobacteriia 976|Bacteroidetes S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 CMS3_k127_3298307_0 1122176.KB903565_gene3332 6.216e-235 736.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IRNP@117747|Sphingobacteriia 976|Bacteroidetes P domain protein - - - - - - - - - - - - Lactamase_B,Rhodanese CMS3_k127_3298307_6 929562.Emtol_0587 7.561e-19 89.0 COG0607@1|root,COG0607@2|Bacteria,4NSD1@976|Bacteroidetes,47SAY@768503|Cytophagia 976|Bacteroidetes P PFAM Rhodanese-like domain - - - - - - - - - - - - Rhodanese CMS3_k127_3298307_2 700598.Niako_4589 2.005e-89 306.0 COG3288@1|root,COG3288@2|Bacteria,4NGH1@976|Bacteroidetes,1IPTC@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Alanine dehydrogenase PNT pntAA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N CMS3_k127_3298307_5 1121904.ARBP01000010_gene2239 5.975e-37 141.0 COG3288@1|root,COG3288@2|Bacteria,4NT78@976|Bacteroidetes,47RF1@768503|Cytophagia 976|Bacteroidetes C 4TM region of pyridine nucleotide transhydrogenase, mitoch pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM CMS3_k127_3298307_1 1122176.KB903543_gene574 3.952e-160 517.0 COG1282@1|root,COG1282@2|Bacteria,4NHGZ@976|Bacteroidetes,1IPVT@117747|Sphingobacteriia 976|Bacteroidetes C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB CMS3_k127_3298307_7 313603.FB2170_17341 1.375e-16 81.0 2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1I507@117743|Flavobacteriia,2PHTD@252356|Maribacter 976|Bacteroidetes S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 CMS3_k127_3306832_3 1121930.AQXG01000008_gene209 3.533e-77 273.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3306832_8 929556.Solca_0257 4.156e-05 46.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IQ8S@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3306832_7 1233951.IO90_04610 8.074e-07 57.0 COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,1HYKJ@117743|Flavobacteriia,3HHYI@358033|Chryseobacterium 976|Bacteroidetes M Belongs to the peptidase S8 family aprN - - - - - - - - - - - Peptidase_S8 CMS3_k127_3306832_4 1484460.JSWG01000014_gene1244 2.026e-51 196.0 COG0515@1|root,COG5295@1|root,COG0515@2|Bacteria,COG5295@2|Bacteria,4NMJW@976|Bacteroidetes,1I19T@117743|Flavobacteriia 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - DUF1566,Peptidase_S74 CMS3_k127_3306832_2 1121904.ARBP01000003_gene6388 4.057e-103 347.0 COG1120@1|root,COG1120@2|Bacteria,4NG1Q@976|Bacteroidetes,47KI0@768503|Cytophagia 976|Bacteroidetes HP ABC transporter fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran CMS3_k127_3306832_0 1121904.ARBP01000003_gene6387 3.524e-133 433.0 COG0609@1|root,COG0609@2|Bacteria,4NEDU@976|Bacteroidetes,47KF2@768503|Cytophagia 976|Bacteroidetes P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD CMS3_k127_3306832_6 1189612.A33Q_3941 8.45e-10 69.0 2DQSW@1|root,338FU@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_3306832_5 385682.AFSL01000071_gene1429 5.287e-32 134.0 COG1595@1|root,COG1595@2|Bacteria,4NS12@976|Bacteroidetes,2FQ76@200643|Bacteroidia,3XK0H@558415|Marinilabiliaceae 976|Bacteroidetes K Bacterial regulatory proteins, luxR family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_3306832_1 1408433.JHXV01000005_gene2495 2.935e-103 350.0 COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,1HXBU@117743|Flavobacteriia,2PC5Y@246874|Cryomorphaceae 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3309339_4 700598.Niako_3251 3.686e-35 136.0 COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia 976|Bacteroidetes DZ Kelch repeat type 1 - - - - - - - - - - - - Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG CMS3_k127_3309339_2 700598.Niako_3251 2.233e-74 269.0 COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia 976|Bacteroidetes DZ Kelch repeat type 1 - - - - - - - - - - - - Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG CMS3_k127_3309339_1 497964.CfE428DRAFT_6304 9.153e-103 351.0 COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia 74201|Verrucomicrobia G Belongs to the binding-protein-dependent transport system permease family - - - - - - - - - - - - BPD_transp_2 CMS3_k127_3309339_0 313628.LNTAR_12346 1.73e-200 635.0 COG1129@1|root,COG1129@2|Bacteria 2|Bacteria G ABC transporter - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran CMS3_k127_3309339_3 1121904.ARBP01000001_gene5673 6.297e-49 181.0 COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47P5N@768503|Cytophagia 976|Bacteroidetes P Na+/Pi-cotransporter - - - ko:K14683 - - - - ko00000,ko02000,ko04147 2.A.58.1 - - Na_Pi_cotrans CMS3_k127_3324335_1 1550091.JROE01000004_gene1841 4.77e-70 241.0 COG0564@1|root,COG0564@2|Bacteria,4NGB1@976|Bacteroidetes,1IQT2@117747|Sphingobacteriia 976|Bacteroidetes J pseudouridylate synthase truC - 5.4.99.26 ko:K06175 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_2 CMS3_k127_3324335_3 1121904.ARBP01000001_gene5778 3.767e-34 138.0 COG0739@1|root,COG4219@1|root,COG0739@2|Bacteria,COG4219@2|Bacteria,4NGHH@976|Bacteroidetes,47NA5@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family M23 - - - - - - - - - - - - Peptidase_M23,Peptidase_M56 CMS3_k127_3324335_2 388413.ALPR1_01185 2.46e-36 140.0 29D8R@1|root,3006P@2|Bacteria,4NNGD@976|Bacteroidetes,47R44@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3324335_0 1122621.ATZA01000022_gene1506 6.192e-100 338.0 COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia 976|Bacteroidetes U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 CMS3_k127_3325602_0 1123020.AUIE01000010_gene1146 6.505e-154 514.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1SZFR@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Multicopper oxidase - - 1.16.3.3 ko:K06324 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 CMS3_k127_3325602_2 880073.Calab_0829 8.339e-14 85.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane CMS3_k127_3325602_1 313603.FB2170_14833 4.824e-54 192.0 COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PG6S@252356|Maribacter 976|Bacteroidetes O Cytochrome C assembly protein ccmC - - - - - - - - - - - Cytochrom_C_asm,ResB CMS3_k127_3332681_0 746697.Aeqsu_2889 0.0 1231.0 COG1982@1|root,COG1982@2|Bacteria,4NHSM@976|Bacteroidetes,1I0X3@117743|Flavobacteriia 976|Bacteroidetes E PFAM Orn Lys Arg decarboxylase, C-terminal domain - - 4.1.1.19 ko:K01584 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C CMS3_k127_3332681_1 1120951.AUBG01000003_gene2783 3.834e-275 852.0 COG0189@1|root,COG0189@2|Bacteria,4PP09@976|Bacteroidetes,1IKCX@117743|Flavobacteriia 976|Bacteroidetes HJ ligase activity - - - - - - - - - - - - - CMS3_k127_3332681_2 313606.M23134_08400 5.159e-221 692.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,47K4A@768503|Cytophagia 976|Bacteroidetes C PFAM Aldehyde dehydrogenase gabD - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 ko:K00128,ko:K00135 ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130 M00027,M00135 R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_3332681_3 485917.Phep_0681 9.183e-133 427.0 COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,1ITT0@117747|Sphingobacteriia 976|Bacteroidetes S SIS domain - - - - - - - - - - - - SIS_2 CMS3_k127_3332681_6 1408473.JHXO01000012_gene478 2.613e-94 320.0 COG1940@1|root,COG1940@2|Bacteria,4NHNJ@976|Bacteroidetes,2FQHI@200643|Bacteroidia 976|Bacteroidetes GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK CMS3_k127_3332681_9 338963.Pcar_1054 2.002e-58 207.0 COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,42T2P@68525|delta/epsilon subdivisions,2WPQ3@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Cupin superfamily (DUF985) - - - ko:K09705 - - - - ko00000 - - - Cupin_5 CMS3_k127_3332681_8 1453500.AT05_09375 4.573e-67 241.0 COG2067@1|root,COG2067@2|Bacteria 2|Bacteria I long-chain fatty acid transporting porin activity - - - - - - - - - - - - - CMS3_k127_3332681_10 138119.DSY0716 5.937e-54 196.0 2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,263F4@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - CMS3_k127_3332681_5 1453500.AT05_09380 6.518e-102 347.0 COG3391@1|root,COG3391@2|Bacteria,4P4CR@976|Bacteroidetes 976|Bacteroidetes S amine dehydrogenase activity - - - - - - - - - - - - - CMS3_k127_3332681_7 1121889.AUDM01000009_gene1209 2.693e-77 270.0 COG0500@1|root,COG2226@2|Bacteria,4NI7T@976|Bacteroidetes,1ICNZ@117743|Flavobacteriia,2NTXN@237|Flavobacterium 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_31 CMS3_k127_3332681_4 382464.ABSI01000010_gene3498 1.695e-117 392.0 COG4225@1|root,COG4225@2|Bacteria 2|Bacteria S unsaturated chondroitin disaccharide hydrolase activity - - - - - - - - - - - - BNR_4 CMS3_k127_3332681_11 710696.Intca_1127 2.491e-29 134.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - ASH,BNR,BNR_2,DUF11,SBBP CMS3_k127_3335376_1 1121904.ARBP01000008_gene3263 4.609e-72 247.0 COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,47JFT@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 65, N-terminal domain - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Glyco_hyd_65N_2 CMS3_k127_3335376_3 926562.Oweho_3448 6.701e-27 119.0 28JFU@1|root,30YB4@2|Bacteria,4PC31@976|Bacteroidetes,1ICTS@117743|Flavobacteriia,2PC4T@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3335376_0 926562.Oweho_3447 4.048e-89 304.0 COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia 2|Bacteria C cytochrome C peroxidase mauG - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C CMS3_k127_3335376_2 1123057.P872_20775 3.348e-51 208.0 COG0515@1|root,COG3177@1|root,COG0515@2|Bacteria,COG3177@2|Bacteria,4NR8T@976|Bacteroidetes,47QX8@768503|Cytophagia 976|Bacteroidetes KLT Domain of unknown function (DUF4157) - - - - - - - - - - - - DUF4157,Pkinase CMS3_k127_3338000_8 1123278.KB893613_gene5223 9.41e-34 136.0 COG1100@1|root,COG1611@1|root,COG1100@2|Bacteria,COG1611@2|Bacteria 2|Bacteria S cytokinin biosynthetic process CP_0264 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox,TIR_2 CMS3_k127_3338000_6 761193.Runsl_3657 1.089e-60 215.0 COG4636@1|root,COG4636@2|Bacteria,4NNM9@976|Bacteroidetes,47Q1A@768503|Cytophagia 976|Bacteroidetes S Putative restriction endonuclease - - - - - - - - - - - - Uma2 CMS3_k127_3338000_0 96561.Dole_2176 1.189e-221 702.0 COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,42N3T@68525|delta/epsilon subdivisions,2WIVU@28221|Deltaproteobacteria,2MMTK@213118|Desulfobacterales 28221|Deltaproteobacteria E Pfam:DUF1446 - - - - - - - - - - - - AtuA CMS3_k127_3338000_3 926550.CLDAP_37850 9.694e-121 400.0 COG0665@1|root,COG0665@2|Bacteria,2G6XM@200795|Chloroflexi 200795|Chloroflexi E FAD dependent oxidoreductase - - 1.5.3.1 ko:K00301 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO CMS3_k127_3338000_4 1166018.FAES_4381 5.499e-107 352.0 COG0247@1|root,COG0247@2|Bacteria,4NIMP@976|Bacteroidetes,47KGV@768503|Cytophagia 976|Bacteroidetes C Fe-S oxidoreductase - - - ko:K18928 - - - - ko00000 - - - CCG CMS3_k127_3338000_2 1121904.ARBP01000002_gene7044 2.866e-188 598.0 COG1139@1|root,COG1139@2|Bacteria,4NEBT@976|Bacteroidetes,47K0Z@768503|Cytophagia 976|Bacteroidetes C LUD domain - - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom CMS3_k127_3338000_7 926556.Echvi_1567 4.403e-41 158.0 COG1556@1|root,COG1556@2|Bacteria,4NQSF@976|Bacteroidetes,47QGX@768503|Cytophagia 976|Bacteroidetes S LUD domain lutC - - ko:K00782 - - - - ko00000 - - - LUD_dom CMS3_k127_3338000_1 216432.CA2559_03260 1.078e-198 629.0 COG1233@1|root,COG1233@2|Bacteria,4NF31@976|Bacteroidetes,1HYWT@117743|Flavobacteriia 976|Bacteroidetes Q Flavin containing amine oxidoreductase pys - - - - - - - - - - - Amino_oxidase,NAD_binding_8 CMS3_k127_3338000_5 1265503.KB905170_gene176 6.878e-64 241.0 COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q7NV@267889|Colwelliaceae 1236|Gammaproteobacteria T Two component regulator propeller - - - ko:K19694 - - - - ko00000,ko01001,ko02022 - - - 7TMR-DISM_7TM,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y,dCache_1 CMS3_k127_334055_3 504472.Slin_3260 1.504e-141 457.0 COG5042@1|root,COG5042@2|Bacteria,4P1AM@976|Bacteroidetes,47U7I@768503|Cytophagia 976|Bacteroidetes F Purine nucleoside permease (NUP) - - - - - - - - - - - - NUP CMS3_k127_334055_1 1121904.ARBP01000010_gene2434 3.966e-162 526.0 COG1816@1|root,COG1816@2|Bacteria,4NG5W@976|Bacteroidetes,47TPF@768503|Cytophagia 976|Bacteroidetes F Adenosine/AMP deaminase add - 3.5.4.4 ko:K01488,ko:K19572 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase CMS3_k127_334055_4 1047013.AQSP01000100_gene588 5.315e-99 334.0 COG3949@1|root,COG3949@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_334055_5 643867.Ftrac_2084 6.133e-50 188.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,47UID@768503|Cytophagia 976|Bacteroidetes T COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein - - - - - - - - - - - - Usp CMS3_k127_334055_2 1122176.KB903532_gene2712 1.75e-142 462.0 COG0613@1|root,COG0613@2|Bacteria,4NHZ5@976|Bacteroidetes,1ISEJ@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - DUF5001,PHP CMS3_k127_334055_0 1237149.C900_00118 0.0 1314.0 COG3696@1|root,COG3696@2|Bacteria,4P36A@976|Bacteroidetes,47JC4@768503|Cytophagia 976|Bacteroidetes P Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family czcA - - ko:K15726 - - - - ko00000,ko02000 2.A.6.1.2 - - ACR_tran,OEP CMS3_k127_3342472_5 385682.AFSL01000074_gene1233 3.612e-07 55.0 COG3630@1|root,COG3630@2|Bacteria,4NXVZ@976|Bacteroidetes,2G1YC@200643|Bacteroidia,3XKDF@558415|Marinilabiliaceae 976|Bacteroidetes C Sodium pump decarboxylase gamma subunit - - 4.1.1.3 ko:K01573 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_gamma CMS3_k127_3342472_1 1121904.ARBP01000002_gene6972 2.836e-158 507.0 COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,4NMEK@976|Bacteroidetes,47K5E@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin CMS3_k127_3342472_3 1121100.JCM6294_3447 5.614e-82 282.0 COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,2FPM3@200643|Bacteroidia,4AKBG@815|Bacteroidaceae 976|Bacteroidetes H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB CMS3_k127_3342472_2 1288963.ADIS_3293 1.56e-132 434.0 28JXN@1|root,2Z9N3@2|Bacteria,4NJUA@976|Bacteroidetes,47NJF@768503|Cytophagia 976|Bacteroidetes S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - FG-GAP,VCBS CMS3_k127_3342472_4 760192.Halhy_1586 8.299e-47 181.0 COG2931@1|root,COG2931@2|Bacteria,4NKF1@976|Bacteroidetes,1IVE6@117747|Sphingobacteriia 976|Bacteroidetes Q A domain in the BMP inhibitor chordin and in microbial proteins. - - - - - - - - - - - - CHRD,SusE CMS3_k127_3342472_0 471854.Dfer_1237 5.043e-191 604.0 COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47NPG@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_3344603_11 1166018.FAES_4486 1.385e-25 109.0 COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,47JMC@768503|Cytophagia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg CMS3_k127_3344603_10 760192.Halhy_2433 2.66e-31 124.0 COG0724@1|root,COG0724@2|Bacteria,4NT1J@976|Bacteroidetes,1ITMI@117747|Sphingobacteriia 976|Bacteroidetes S PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - - - - - - - - - - RRM_1 CMS3_k127_3344603_5 1408433.JHXV01000001_gene844 1.746e-68 237.0 COG0664@1|root,COG0664@2|Bacteria,4NIP0@976|Bacteroidetes,1I1J0@117743|Flavobacteriia 976|Bacteroidetes T cyclic nucleotide-binding - - - - - - - - - - - - cNMP_binding CMS3_k127_3344603_12 468059.AUHA01000002_gene1271 5.062e-08 56.0 COG3055@1|root,COG3055@2|Bacteria,4NG50@976|Bacteroidetes,1IRK4@117747|Sphingobacteriia 976|Bacteroidetes DZ Kelch repeat type 1 - - - - - - - - - - - - Kelch_1,Kelch_3,Kelch_4,Kelch_6,TIG CMS3_k127_3344603_9 266748.HY04_05035 8.068e-48 176.0 COG0457@1|root,COG0457@2|Bacteria,4NSXM@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 CMS3_k127_3344603_3 1122179.KB890416_gene2698 1.869e-76 264.0 COG1030@1|root,COG1030@2|Bacteria,4PN0T@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - TspO_MBR CMS3_k127_3344603_1 1499967.BAYZ01000016_gene6566 6.707e-92 308.0 COG0363@1|root,COG0363@2|Bacteria,2NR1W@2323|unclassified Bacteria 2|Bacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase nagB - 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso CMS3_k127_3344603_4 382464.ABSI01000010_gene3488 2.263e-75 274.0 COG0591@1|root,COG0591@2|Bacteria 2|Bacteria E symporter activity - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_3344603_2 1122176.KB903565_gene3243 1.717e-87 303.0 COG2010@1|root,COG2010@2|Bacteria,4NHY4@976|Bacteroidetes,1IRVC@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - - CMS3_k127_3344603_7 1122176.KB903565_gene3242 5.15e-50 183.0 COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,1IY7U@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS3_k127_3344603_8 1122176.KB903554_gene3900 4.94e-48 176.0 COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1ISW6@117747|Sphingobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - Rrf2 CMS3_k127_3344603_6 1250232.JQNJ01000001_gene2751 1.902e-51 188.0 COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,1I1DK@117743|Flavobacteriia 976|Bacteroidetes M COG2335 Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - Fasciclin CMS3_k127_3344603_0 1122176.KB903565_gene3240 1.287e-315 975.0 COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1IQ1B@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Cytochrome C oxidase subunit II, periplasmic domain nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - - CMS3_k127_3345906_1 1288963.ADIS_1259 4.673e-76 261.0 COG3119@1|root,COG3119@2|Bacteria,4NGPC@976|Bacteroidetes 976|Bacteroidetes P Pfam Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_3345906_0 1288963.ADIS_0486 8.565e-247 773.0 COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,47MPU@768503|Cytophagia 976|Bacteroidetes G glycoside hydrolase family 2 sugar binding - - - - - - - - - - - - Glyco_hydro_106 CMS3_k127_335012_8 1196324.A374_13880 0.0002042 49.0 COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,4HPNY@91061|Bacilli 91061|Bacilli K Transcriptional regulator ypoP GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR CMS3_k127_335012_2 1122179.KB890437_gene1492 7.531e-76 264.0 COG0714@1|root,COG0714@2|Bacteria,4NPWR@976|Bacteroidetes 976|Bacteroidetes S ATPase associated with various cellular activities, AAA_5 - - - - - - - - - - - - AAA_5 CMS3_k127_335012_0 1121422.AUMW01000029_gene39 1.522e-263 826.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae 186801|Clostridia H Belongs to the UbiD family - - 4.1.1.61,4.1.1.98 ko:K03182,ko:K16239 ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120 M00117 R01238,R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD CMS3_k127_335012_3 1123057.P872_11375 1.704e-75 265.0 COG0142@1|root,COG0142@2|Bacteria,4NEGQ@976|Bacteroidetes,47JRS@768503|Cytophagia 976|Bacteroidetes H Belongs to the FPP GGPP synthase family idsA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt CMS3_k127_335012_5 1122176.KB903587_gene4516 2.68e-37 156.0 COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes 976|Bacteroidetes DZ Pkd domain containing protein - - - - - - - - - - - - CHU_C,PKD,SASA,SprB CMS3_k127_335012_6 755732.Fluta_2564 6.797e-08 63.0 28U74@1|root,32HUI@2|Bacteria,4NRCX@976|Bacteroidetes,1IIG8@117743|Flavobacteriia 976|Bacteroidetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_335012_7 760192.Halhy_4115 8.926e-06 51.0 COG0708@1|root,COG0708@2|Bacteria,4PJCI@976|Bacteroidetes,1J011@117747|Sphingobacteriia 976|Bacteroidetes L Exodeoxyribonuclease III - - - - - - - - - - - - - CMS3_k127_335012_4 1237149.C900_04045 5.127e-38 156.0 COG3595@1|root,COG3595@2|Bacteria,4NMHT@976|Bacteroidetes,47PEC@768503|Cytophagia 976|Bacteroidetes S Putative adhesin - - - - - - - - - - - - DUF4097 CMS3_k127_335012_1 1185876.BN8_04474 1.444e-184 601.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate CMS3_k127_3358886_3 1313421.JHBV01000008_gene4325 1.497e-32 138.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1IU5A@117747|Sphingobacteriia 976|Bacteroidetes T COG0589 Universal stress protein UspA and related nucleotide-binding uspA - - - - - - - - - - - DUF2007,Usp CMS3_k127_3358886_2 1121898.Q766_00410 6.258e-33 140.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia,2NTBS@237|Flavobacterium 976|Bacteroidetes T Universal stress protein uspA - - - - - - - - - - - DUF2007,Usp CMS3_k127_3358886_0 643867.Ftrac_2644 7.29e-61 221.0 COG0589@1|root,COG0589@2|Bacteria,4NER9@976|Bacteroidetes,47PF0@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp CMS3_k127_3358886_1 1443665.JACA01000020_gene4875 6.326e-52 202.0 COG0457@1|root,COG0457@2|Bacteria,4NMWW@976|Bacteroidetes,1IA1W@117743|Flavobacteriia,2YKHM@290174|Aquimarina 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - DUF2974,NB-ARC,Sel1,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8 CMS3_k127_3370409_4 1123057.P872_20890 3.779e-21 95.0 COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,47PF6@768503|Cytophagia 976|Bacteroidetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase CMS3_k127_3370409_1 926549.KI421517_gene3733 5.143e-107 355.0 COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,47K0S@768503|Cytophagia 976|Bacteroidetes F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C CMS3_k127_3370409_2 553178.CAPGI0001_0989 4.931e-77 263.0 COG0602@1|root,COG0602@2|Bacteria,4NESC@976|Bacteroidetes,1HWTZ@117743|Flavobacteriia,1EQ9D@1016|Capnocytophaga 976|Bacteroidetes H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM CMS3_k127_3370409_0 714943.Mucpa_0218 7.819e-143 476.0 COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia 976|Bacteroidetes MU Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40,TPR_16,TPR_2,TPR_8 CMS3_k127_3370409_6 1168289.AJKI01000011_gene441 3.137e-14 83.0 2ES6Q@1|root,33JRG@2|Bacteria,4NXZG@976|Bacteroidetes,2G249@200643|Bacteroidia,3XJNS@558415|Marinilabiliaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3370409_3 1122621.ATZA01000009_gene284 9.919e-48 178.0 COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1ITHJ@117747|Sphingobacteriia 976|Bacteroidetes EG EamA-like transporter family - - - - - - - - - - - - EamA CMS3_k127_3370409_5 1122605.KB893626_gene2437 3.667e-16 78.0 COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IQRK@117747|Sphingobacteriia 976|Bacteroidetes S protein conserved in bacteria - - - - - - - - - - - - DUF3131,Glycoamylase CMS3_k127_3372721_0 504472.Slin_5004 9.34e-204 651.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NKGP@976|Bacteroidetes,47M97@768503|Cytophagia 976|Bacteroidetes C pyrroloquinoline quinone binding - - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_3372721_1 1122176.KB903550_gene4289 6.256e-54 212.0 COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,1IPFX@117747|Sphingobacteriia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD CMS3_k127_3375033_0 1239962.C943_02101 1.149e-171 548.0 COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,47JIN@768503|Cytophagia 976|Bacteroidetes C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt CMS3_k127_3375033_1 1550091.JROE01000013_gene15 3.159e-136 442.0 COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1IP0K@117747|Sphingobacteriia 976|Bacteroidetes I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA CMS3_k127_3375033_3 1189619.pgond44_03825 6.673e-78 268.0 COG0253@1|root,COG0253@2|Bacteria,4NF26@976|Bacteroidetes,1HY3U@117743|Flavobacteriia,4C2XK@83612|Psychroflexus 976|Bacteroidetes E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase CMS3_k127_3375033_2 1121904.ARBP01000028_gene1699 5.226e-91 306.0 COG3279@1|root,COG3279@2|Bacteria,4NGBF@976|Bacteroidetes 976|Bacteroidetes KT Response regulator of the LytR AlgR family - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_3375033_4 706436.HMPREF9074_07149 2.664e-11 64.0 COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia,1EQJQ@1016|Capnocytophaga 976|Bacteroidetes E Psort location Periplasmic, score 9.44 ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N CMS3_k127_3377644_3 385682.AFSL01000015_gene2653 2.57e-09 61.0 COG1598@1|root,COG1598@2|Bacteria,4NRY6@976|Bacteroidetes 976|Bacteroidetes S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - - CMS3_k127_3377644_2 1250232.JQNJ01000001_gene3382 1.983e-10 63.0 COG1476@1|root,COG1476@2|Bacteria,4NV6T@976|Bacteroidetes,1I6WE@117743|Flavobacteriia 976|Bacteroidetes K Helix-turn-helix type 3 - - - - - - - - - - - - HTH_26,HTH_3 CMS3_k127_3377644_1 1121104.AQXH01000001_gene961 1.646e-102 343.0 COG1680@1|root,COG1680@2|Bacteria 2|Bacteria V peptidase activity - - - - - - - - - - - - Beta-lactamase CMS3_k127_3377644_0 1120966.AUBU01000001_gene957 5.788e-174 550.0 COG0451@1|root,COG0451@2|Bacteria,4NIQY@976|Bacteroidetes,47MP7@768503|Cytophagia 976|Bacteroidetes M NAD(P)H-binding - - - - - - - - - - - - 3Beta_HSD,Epimerase CMS3_k127_3383084_0 649349.Lbys_0013 2.125e-112 368.0 COG3718@1|root,COG3718@2|Bacteria,4NKW4@976|Bacteroidetes,47TKD@768503|Cytophagia 976|Bacteroidetes G KduI/IolB family - - 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08503 RC00541 ko00000,ko00001,ko01000 - - - KduI CMS3_k127_3383084_1 1121904.ARBP01000016_gene5249 3.845e-104 349.0 COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,47JPM@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 CMS3_k127_3383084_2 313606.M23134_03259 3.084e-41 156.0 COG0735@1|root,COG0735@2|Bacteria,4NSES@976|Bacteroidetes,47PU3@768503|Cytophagia 976|Bacteroidetes P Belongs to the Fur family zur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR CMS3_k127_3385329_0 1120968.AUBX01000016_gene1706 5.573e-172 547.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia 976|Bacteroidetes S PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_3385329_1 760192.Halhy_4242 2.417e-52 193.0 COG3794@1|root,COG3794@2|Bacteria,4P61R@976|Bacteroidetes,1IZAS@117747|Sphingobacteriia 976|Bacteroidetes C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - - CMS3_k127_3385329_2 760192.Halhy_4243 1.045e-08 59.0 28IVM@1|root,2Z8U0@2|Bacteria,4P4P5@976|Bacteroidetes,1IYIB@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3387898_3 485918.Cpin_1026 4.02e-32 136.0 COG1807@1|root,COG1807@2|Bacteria,4NEU7@976|Bacteroidetes,1IR4N@117747|Sphingobacteriia 976|Bacteroidetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - - - - - - - - - - PMT_2 CMS3_k127_3387898_2 204536.SULAZ_1471 4.035e-33 133.0 COG5502@1|root,COG5502@2|Bacteria 2|Bacteria V conserved protein (DUF2267) - - 2.1.1.72 ko:K03427,ko:K06910,ko:K07005 - - - - ko00000,ko01000,ko02048 - - - DUF2267 CMS3_k127_3387898_0 1123242.JH636435_gene1908 4.554e-83 298.0 COG0433@1|root,COG0561@1|root,COG0433@2|Bacteria,COG0561@2|Bacteria,2IXQK@203682|Planctomycetes 203682|Planctomycetes S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - DUF87,Hydrolase_3 CMS3_k127_3387898_1 1166018.FAES_0145 2.365e-41 171.0 28KVV@1|root,2ZACB@2|Bacteria,4NHPI@976|Bacteroidetes,47MDK@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3389644_3 1040982.AXAL01000011_gene1154 1.518e-12 72.0 COG0457@1|root,COG0457@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria,43RSN@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 CMS3_k127_3389644_0 1313301.AUGC01000012_gene1384 0.0 1347.0 COG0209@1|root,COG0209@2|Bacteria,4NEHQ@976|Bacteroidetes 976|Bacteroidetes F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrd - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_lgC,Ribonuc_red_lgN CMS3_k127_3389644_1 1121129.KB903360_gene3618 8.312e-203 661.0 COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia,22VZ1@171551|Porphyromonadaceae 976|Bacteroidetes S membrane - - - - - - - - - - - - YfhO CMS3_k127_3389644_2 1150600.ADIARSV_3982 4.549e-92 306.0 COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1IPV3@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CMS3_k127_339262_2 391596.PBAL39_19854 5.685e-81 278.0 COG1611@1|root,COG1611@2|Bacteria,4NF20@976|Bacteroidetes,1IQFQ@117747|Sphingobacteriia 976|Bacteroidetes S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox CMS3_k127_339262_0 1453498.LG45_08215 2.289e-289 911.0 COG0474@1|root,COG0474@2|Bacteria,4NERM@976|Bacteroidetes,1HY67@117743|Flavobacteriia,2NT0H@237|Flavobacterium 976|Bacteroidetes P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase CMS3_k127_339262_1 1250232.JQNJ01000001_gene30 1.146e-139 451.0 COG1052@1|root,COG1052@2|Bacteria,4NF1R@976|Bacteroidetes,1HZJN@117743|Flavobacteriia 976|Bacteroidetes CH D-isomer specific 2-hydroxyacid dehydrogenase ldhA - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C CMS3_k127_3395635_0 1123276.KB893265_gene4532 2.946e-28 122.0 COG1595@1|root,COG1595@2|Bacteria,4NP91@976|Bacteroidetes,47PTK@768503|Cytophagia 976|Bacteroidetes K DNA-templated transcription, initiation - - - - - - - - - - - - - CMS3_k127_3395635_1 349163.Acry_2380 1.355e-09 67.0 COG3916@1|root,COG3916@2|Bacteria 2|Bacteria QT Acyl-homoserine-lactone synthase - - - - - - - - - - - - AIRS,AIRS_C,Acetyltransf_1,Acetyltransf_10,Aminotran_5 CMS3_k127_3399864_2 1237149.C900_05760 3.813e-09 67.0 COG5662@1|root,COG5662@2|Bacteria,4NP57@976|Bacteroidetes,47PYK@768503|Cytophagia 976|Bacteroidetes K AntiSigma factor - - - - - - - - - - - - TPR_6 CMS3_k127_3399864_0 1150864.MILUP08_42286 2.614e-68 261.0 COG2931@1|root,COG2931@2|Bacteria,2GX6F@201174|Actinobacteria,4DMC1@85008|Micromonosporales 201174|Actinobacteria Q Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - Peptidase_S8,Tyrosinase,VCBS CMS3_k127_3399864_1 1267534.KB906756_gene707 1.563e-21 99.0 2CIGD@1|root,2ZM6I@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_3400985_6 1121012.AUKX01000025_gene563 1.42e-93 311.0 COG3509@1|root,COG3509@2|Bacteria,4NENB@976|Bacteroidetes,1HZX4@117743|Flavobacteriia,23FSE@178469|Arenibacter 976|Bacteroidetes G Carbohydrate-binding family 9 - - - - - - - - - - - - CBM9_1 CMS3_k127_3400985_4 641524.ADICYQ_0900 8.737e-109 357.0 COG3836@1|root,COG3836@2|Bacteria,4NG3S@976|Bacteroidetes,47NSV@768503|Cytophagia 976|Bacteroidetes G HpcH/HpaI aldolase/citrate lyase family - - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI CMS3_k127_3400985_1 641524.ADICYQ_0898 1.403e-186 603.0 COG0591@1|root,COG1413@1|root,COG0591@2|Bacteria,COG1413@2|Bacteria,4P183@976|Bacteroidetes,47V49@768503|Cytophagia 2|Bacteria CE Sodium:solute symporter family - - 3.4.24.3 ko:K01387,ko:K03301,ko:K03307 - - - - ko00000,ko01000,ko01002,ko02042 2.A.12,2.A.21 - - DUF1822,Peptidase_M9,Peptidase_M9_N,SSF CMS3_k127_3400985_9 313606.M23134_03547 3.151e-09 70.0 COG1413@1|root,COG1413@2|Bacteria,4NMRF@976|Bacteroidetes 976|Bacteroidetes C lyase activity - - - - - - - - - - - - - CMS3_k127_3400985_7 449447.MAE_11540 7.239e-31 130.0 COG1413@1|root,COG1413@2|Bacteria,1G2TK@1117|Cyanobacteria 1117|Cyanobacteria C lyase activity - - - - - - - - - - - - - CMS3_k127_3400985_5 1250232.JQNJ01000001_gene1566 7.353e-107 357.0 COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,1HY65@117743|Flavobacteriia 976|Bacteroidetes K lacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CMS3_k127_3400985_2 926556.Echvi_2667 3.521e-186 621.0 COG1506@1|root,COG1506@2|Bacteria,4PKQ3@976|Bacteroidetes,47N9J@768503|Cytophagia 976|Bacteroidetes E Hydrolase Family 16 - - - - - - - - - - - - CBM9_1 CMS3_k127_3400985_0 760192.Halhy_1419 6.305e-257 828.0 COG3250@1|root,COG3250@2|Bacteria,4NEDP@976|Bacteroidetes,1IP3A@117747|Sphingobacteriia 976|Bacteroidetes G Glycosyl hydrolases family 2, sugar binding domain - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - Glyco_hydro_2_N,SASA CMS3_k127_3400985_3 1121904.ARBP01000003_gene6322 2.109e-164 525.0 COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47TJ9@768503|Cytophagia 976|Bacteroidetes E Pfam:SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_3421405_1 1048983.EL17_16785 4.072e-122 398.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia 976|Bacteroidetes C FAD linked oxidases, C-terminal domain - - - ko:K06911 - - - - ko00000 - - - FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8 CMS3_k127_3421405_0 1123508.JH636441_gene3473 8.332e-128 418.0 COG0673@1|root,COG0673@2|Bacteria,2J1RX@203682|Planctomycetes 203682|Planctomycetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_3421405_3 926562.Oweho_2326 9.056e-23 104.0 COG2318@1|root,COG2318@2|Bacteria,4NSE5@976|Bacteroidetes,1I4NU@117743|Flavobacteriia 976|Bacteroidetes S Damage-inducible protein DinB - - - - - - - - - - - - DinB CMS3_k127_3421405_2 1227739.Hsw_0098 1.603e-34 145.0 COG1807@1|root,COG1807@2|Bacteria,4NQJA@976|Bacteroidetes 976|Bacteroidetes M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 CMS3_k127_3422947_1 313606.M23134_08314 8.541e-54 198.0 COG1595@1|root,COG1595@2|Bacteria,4NU4K@976|Bacteroidetes,47UQA@768503|Cytophagia 976|Bacteroidetes K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_3422947_0 641524.ADICYQ_1823 3.872e-138 449.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,47JY8@768503|Cytophagia 976|Bacteroidetes G Belongs to the GHMP kinase family. GalK subfamily galK - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg CMS3_k127_3425446_2 1313421.JHBV01000033_gene2387 6.848e-43 178.0 COG0384@1|root,COG2132@1|root,COG0384@2|Bacteria,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase_3,PhzC-PhzF,SprB CMS3_k127_3425446_3 1121930.AQXG01000004_gene2868 4.011e-17 96.0 COG1572@1|root,COG2911@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG4733@2|Bacteria,4NYS6@976|Bacteroidetes,1IZ9T@117747|Sphingobacteriia 976|Bacteroidetes S Parallel beta-helix repeats - - - - - - - - - - - - - CMS3_k127_3425446_1 565033.GACE_0682 5.882e-52 193.0 COG0730@1|root,arCOG09610@2157|Archaea 2157|Archaea S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS3_k127_3425446_4 1125725.HMPREF1325_0764 1.253e-10 68.0 COG0527@1|root,COG0527@2|Bacteria,2J6FK@203691|Spirochaetes 203691|Spirochaetes E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 CMS3_k127_3437429_1 313603.FB2170_02175 6.468e-158 507.0 COG1858@1|root,COG1858@2|Bacteria,4NEKS@976|Bacteroidetes,1HZT9@117743|Flavobacteriia,2PHMP@252356|Maribacter 976|Bacteroidetes C Di-haem cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C CMS3_k127_3437429_2 391603.FBALC1_10877 6.327e-32 129.0 COG4430@1|root,COG4430@2|Bacteria,4PMRA@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF3052) - - - - - - - - - - - - DUF3052 CMS3_k127_3437429_0 760192.Halhy_1483 2.463e-214 680.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IQRG@117747|Sphingobacteriia 976|Bacteroidetes E peptidase S9 - - - - - - - - - - - - DPPIV_N,Peptidase_S9 CMS3_k127_3457955_2 487796.Flav2ADRAFT_1261 8.285e-08 55.0 COG1428@1|root,COG1428@2|Bacteria,4NFA8@976|Bacteroidetes,1HXE9@117743|Flavobacteriia 976|Bacteroidetes F deoxynucleoside kinase dck - - - - - - - - - - - dNK CMS3_k127_3457955_1 929556.Solca_4410 6.994e-133 438.0 COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1IQPD@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr CMS3_k127_3457955_0 1313301.AUGC01000001_gene1456 3.896e-213 697.0 COG0747@1|root,COG4288@1|root,COG0747@2|Bacteria,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes 976|Bacteroidetes E Lamin Tail Domain - - - - - - - - - - - - Big_5,CHU_C,LTD CMS3_k127_3460172_1 153721.MYP_2632 4.165e-108 356.0 COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47JZH@768503|Cytophagia 976|Bacteroidetes C Aldo/keto reductase family - - 1.1.1.65 ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 - R01708 RC00116 ko00000,ko00001,ko01000 - - - Aldo_ket_red CMS3_k127_3460172_0 1121904.ARBP01000016_gene5190 1.032e-191 616.0 COG0469@1|root,COG0469@2|Bacteria,4NGQX@976|Bacteroidetes,47T9Y@768503|Cytophagia 976|Bacteroidetes G Pyruvate kinase, barrel domain - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK CMS3_k127_3460172_6 391603.FBALC1_16447 1.085e-25 126.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - CHU_C,CUB,Cleaved_Adhesin,PKD,fn3 CMS3_k127_3460172_2 906888.JCM19314_1987 1.607e-72 281.0 COG3291@1|root,COG3291@2|Bacteria,4PHVK@976|Bacteroidetes,1IDN4@117743|Flavobacteriia,3HJ5A@363408|Nonlabens 976|Bacteroidetes O Fibronectin type III domain - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - MAM,fn3 CMS3_k127_3460172_3 1122225.AULQ01000002_gene492 2.615e-63 251.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NJU9@976|Bacteroidetes 976|Bacteroidetes MU calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Big_5,PKD CMS3_k127_3460172_4 1122179.KB890416_gene2728 2.112e-50 208.0 COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1IQYI@117747|Sphingobacteriia 976|Bacteroidetes M SprB repeat - - - - - - - - - - - - CHU_C,SdrD_B,SprB CMS3_k127_3460172_5 1123057.P872_02595 2.36e-28 115.0 COG0583@1|root,COG0583@2|Bacteria,4NGAB@976|Bacteroidetes,47NDC@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate CMS3_k127_34678_0 760192.Halhy_1139 1.076e-282 893.0 COG1629@1|root,COG4771@2|Bacteria,4NJBC@976|Bacteroidetes,1J04Q@117747|Sphingobacteriia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug CMS3_k127_34678_2 1122179.KB890416_gene2653 4.003e-135 446.0 28K3I@1|root,2Z9SN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_34678_1 1121904.ARBP01000001_gene5684 2.713e-208 669.0 COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,47KDI@768503|Cytophagia 976|Bacteroidetes G Pyrrolo-quinoline quinone - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ CMS3_k127_34678_3 1380384.JADN01000004_gene2209 1.771e-45 170.0 COG4319@1|root,COG4319@2|Bacteria,4NVXG@976|Bacteroidetes,1I522@117743|Flavobacteriia 976|Bacteroidetes S ketosteroid isomerase - - - - - - - - - - - - DUF4440 CMS3_k127_34678_4 1296416.JACB01000016_gene4481 1.538e-25 115.0 COG2207@1|root,COG2207@2|Bacteria,4NP52@976|Bacteroidetes,1IIPD@117743|Flavobacteriia,2YI93@290174|Aquimarina 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_3470786_1 762903.Pedsa_2264 0.0 1310.0 COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,1INW0@117747|Sphingobacteriia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 CMS3_k127_3470786_0 1121904.ARBP01000003_gene6504 0.0 2059.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,47JP0@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 CMS3_k127_3470786_10 485918.Cpin_5885 1.238e-33 136.0 COG2065@1|root,COG2065@2|Bacteria,4NNRI@976|Bacteroidetes,1ISDB@117747|Sphingobacteriia 976|Bacteroidetes F Pyrimidine operon attenuation protein uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran CMS3_k127_3470786_3 1227739.Hsw_4185 8.499e-192 609.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,47JWG@768503|Cytophagia 976|Bacteroidetes E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT CMS3_k127_3470786_6 1380384.JADN01000007_gene1499 9.334e-74 259.0 COG0805@1|root,COG0805@2|Bacteria,4NEKM@976|Bacteroidetes,1HYNB@117743|Flavobacteriia 976|Bacteroidetes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC CMS3_k127_3470786_11 1121481.AUAS01000005_gene2107 1.625e-28 123.0 COG1011@1|root,COG1011@2|Bacteria,4NQT8@976|Bacteroidetes,47QH7@768503|Cytophagia 976|Bacteroidetes S TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED yihX - 3.1.3.10 ko:K20866 ko00010,ko01120,map00010,map01120 - R00947 RC00078 ko00000,ko00001,ko01000 - - - HAD_2 CMS3_k127_3470786_5 1237149.C900_00779 3.399e-98 336.0 COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,47NVA@768503|Cytophagia 976|Bacteroidetes P PFAM sodium hydrogen exchanger - - - - - - - - - - - - Na_H_Exchanger CMS3_k127_3470786_8 1509405.GV67_10000 3.048e-44 175.0 COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,2TQTY@28211|Alphaproteobacteria,4B9JT@82115|Rhizobiaceae 28211|Alphaproteobacteria S Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - - - - - - - - - - DUF2235 CMS3_k127_3470786_7 1408433.JHXV01000030_gene1405 3.277e-72 263.0 COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,1ICR8@117743|Flavobacteriia,2PBVB@246874|Cryomorphaceae 976|Bacteroidetes UW domain, Protein - - - - - - - - - - - - - CMS3_k127_3470786_12 357808.RoseRS_0444 4.645e-25 109.0 COG3385@1|root,COG3385@2|Bacteria,2G9A6@200795|Chloroflexi 200795|Chloroflexi L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_Tnp_1 CMS3_k127_3470786_2 1123277.KB893172_gene512 3.005e-207 654.0 COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,47NTH@768503|Cytophagia 976|Bacteroidetes IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897,ko:K18660 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C,PP-binding CMS3_k127_3470786_9 1249997.JHZW01000002_gene1714 6.997e-39 148.0 2CAQ0@1|root,32RRS@2|Bacteria,4NRRH@976|Bacteroidetes,1I9QS@117743|Flavobacteriia 976|Bacteroidetes S Malonate transporter MadL subunit - - - - - - - - - - - - MadL CMS3_k127_3470786_4 1249997.JHZW01000002_gene1713 1.784e-101 336.0 28HGK@1|root,2Z7SE@2|Bacteria,4NGDR@976|Bacteroidetes,1I856@117743|Flavobacteriia 976|Bacteroidetes S Malonate/sodium symporter MadM subunit - - - - - - - - - - - - MadM CMS3_k127_3470786_14 1123035.ARLA01000028_gene2469 1.064e-06 62.0 COG1470@1|root,COG4935@1|root,COG1470@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,4C2CH@83612|Psychroflexus 976|Bacteroidetes O Metallo-peptidase family M12 - - - - - - - - - - - - P_proprotein,Reprolysin_3,Reprolysin_4,Reprolysin_5 CMS3_k127_3470786_13 102125.Xen7305DRAFT_00016350 4.795e-22 112.0 COG0823@1|root,COG0823@2|Bacteria,1GJ0J@1117|Cyanobacteria,3VIZ2@52604|Pleurocapsales 1117|Cyanobacteria QU calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - CBM_6,SdrD_B CMS3_k127_3478755_1 382464.ABSI01000014_gene1443 6.729e-99 336.0 COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia,2IUEA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes larC - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 CMS3_k127_3478755_0 880070.Cycma_3676 1.916e-132 430.0 COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,47VYF@768503|Cytophagia 976|Bacteroidetes S Aldo/keto reductase family - - - ko:K07079 - - - - ko00000 - - - Aldo_ket_red,Fer4_17 CMS3_k127_3478755_2 880073.Calab_3790 2.479e-66 240.0 COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria 2|Bacteria K acetyltransferase yghO - - - - - - - - - - - Acetyltransf_1 CMS3_k127_3478755_3 642492.Clole_3992 0.0001409 46.0 COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,24GTY@186801|Clostridia 186801|Clostridia I Psort location - - - ko:K13622 ko00564,map00564 - R09072 RC00021,RC01091 ko00000,ko00001 - - - DUF3419 CMS3_k127_347878_2 1121904.ARBP01000010_gene2407 2.544e-06 52.0 COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia 976|Bacteroidetes I Acetyl propionyl-CoA carboxylase alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl CMS3_k127_347878_0 1279009.ADICEAN_00649 2.244e-175 578.0 COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia 976|Bacteroidetes S COGs COG1033 exporter of the RND superfamily protein - - - ko:K07003 - - - - ko00000 - - - MMPL CMS3_k127_347878_1 1453500.AT05_01805 3.936e-24 111.0 COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,1HXG8@117743|Flavobacteriia 976|Bacteroidetes N Cell envelope biogenesis protein OmpA - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA CMS3_k127_34795_0 1305737.JAFX01000001_gene3138 2.426e-205 649.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_34795_3 880071.Fleli_0688 1.044e-15 82.0 2EF8J@1|root,32MJU@2|Bacteria,4NQFP@976|Bacteroidetes,47QPB@768503|Cytophagia 976|Bacteroidetes S MerC mercury resistance protein - - - - - - - - - - - - MerC CMS3_k127_34795_1 1313421.JHBV01000005_gene4617 1.957e-68 240.0 COG1136@1|root,COG1136@2|Bacteria,4NNS2@976|Bacteroidetes,1IS7P@117747|Sphingobacteriia 976|Bacteroidetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_34795_2 1123277.KB893184_gene4173 2.515e-46 170.0 COG0577@1|root,COG0577@2|Bacteria,4NF60@976|Bacteroidetes,47KE0@768503|Cytophagia 976|Bacteroidetes V ABC-type transport system involved in lipoprotein release permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3483532_0 1121859.KB890754_gene821 2.243e-276 864.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia 976|Bacteroidetes C FAD linked oxidases, C-terminal domain - - - ko:K06911 - - - - ko00000 - - - FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8 CMS3_k127_3483532_2 1227739.Hsw_3997 6.638e-98 328.0 COG0053@1|root,COG0053@2|Bacteria,4NGDQ@976|Bacteroidetes,47TQ6@768503|Cytophagia 976|Bacteroidetes P Cation efflux family - - - - - - - - - - - - Cation_efflux,ZT_dimer CMS3_k127_3483532_1 929703.KE386491_gene3632 2.48e-138 445.0 COG0014@1|root,COG0014@2|Bacteria,4NEPQ@976|Bacteroidetes,47J99@768503|Cytophagia 976|Bacteroidetes E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_3489641_0 411476.BACOVA_05270 7.933e-77 266.0 COG4589@1|root,COG4589@2|Bacteria,4NRIQ@976|Bacteroidetes,2FR5X@200643|Bacteroidia,4AM93@815|Bacteroidaceae 976|Bacteroidetes M Belongs to the CDS family - - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 CMS3_k127_3489641_2 483215.BACFIN_05887 5.685e-38 150.0 COG0204@1|root,COG0204@2|Bacteria,4PD5H@976|Bacteroidetes,2FPX0@200643|Bacteroidia,4AQEN@815|Bacteroidaceae 976|Bacteroidetes I Acyl-transferase - - - - - - - - - - - - Acyltransferase CMS3_k127_3489641_1 497964.CfE428DRAFT_0662 8.118e-46 168.0 2EAUB@1|root,334VZ@2|Bacteria,46VV5@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - CMS3_k127_349332_3 1408473.JHXO01000001_gene2378 2.902e-10 61.0 COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,2FT2N@200643|Bacteroidia 976|Bacteroidetes S FeS assembly SUF system protein yitW - - - - - - - - - - - FeS_assembly_P CMS3_k127_349332_0 986075.CathTA2_0103 8.26e-63 223.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli 91061|Bacilli S Belongs to the SOS response-associated peptidase family yoqW - - - - - - - - - - - SRAP CMS3_k127_349332_1 313606.M23134_01323 5.513e-57 203.0 COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,47QT5@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_3496921_2 886293.Sinac_2682 4.175e-32 127.0 COG1129@1|root,COG1129@2|Bacteria,2IXQH@203682|Planctomycetes 203682|Planctomycetes G transport system, ATPase - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran CMS3_k127_3496921_1 861299.J421_5600 7.162e-77 269.0 COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes 142182|Gemmatimonadetes U Branched-chain amino acid transport system / permease component - - - ko:K10440,ko:K10553 ko02010,map02010 M00212,M00218 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7 - - BPD_transp_2 CMS3_k127_3496921_0 1265503.KB905170_gene176 2.415e-116 403.0 COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q7NV@267889|Colwelliaceae 1236|Gammaproteobacteria T Two component regulator propeller - - - ko:K19694 - - - - ko00000,ko01001,ko02022 - - - 7TMR-DISM_7TM,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y,dCache_1 CMS3_k127_3497482_1 760192.Halhy_1659 1.811e-180 583.0 2EZ48@1|root,30K0H@2|Bacteria,4P965@976|Bacteroidetes,1IZT0@117747|Sphingobacteriia 760192.Halhy_1659|- S IMG reference gene - - - - - - - - - - - - - CMS3_k127_3497482_0 760192.Halhy_1658 1.644e-184 595.0 2EZ48@1|root,30K0H@2|Bacteria,4P965@976|Bacteroidetes,1IZT0@117747|Sphingobacteriia 760192.Halhy_1658|- S IMG reference gene - - - - - - - - - - - - - CMS3_k127_3497482_2 760192.Halhy_1668 4.753e-22 106.0 2DDUQ@1|root,2ZJCQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_351355_1 761193.Runsl_4118 3.317e-10 69.0 2BUJT@1|root,32VAI@2|Bacteria,4NSUJ@976|Bacteroidetes,47WN0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_351355_0 313606.M23134_01012 2.336e-205 647.0 COG1960@1|root,COG1960@2|Bacteria,4NFD4@976|Bacteroidetes,47NH5@768503|Cytophagia 976|Bacteroidetes I Acyl-CoA dehydrogenase, middle domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,SCP2 CMS3_k127_3530465_3 755732.Fluta_3461 4.967e-37 145.0 COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia,2PBBU@246874|Cryomorphaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4 CMS3_k127_3530465_0 926549.KI421517_gene2891 6.036e-220 692.0 COG1239@1|root,COG1239@2|Bacteria,4NF1J@976|Bacteroidetes,47JD2@768503|Cytophagia 976|Bacteroidetes H magnesium chelatase chlI - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - AAA_5,Sigma54_activat CMS3_k127_3530465_1 313603.FB2170_07779 1.419e-79 276.0 COG0318@1|root,COG0318@2|Bacteria,4NDXK@976|Bacteroidetes,1IJB2@117743|Flavobacteriia 976|Bacteroidetes IQ acyl transferase - - - - - - - - - - - - LuxE CMS3_k127_3530465_4 469383.Cwoe_2923 2.875e-07 54.0 2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria 84995|Rubrobacteria - - - - - - - - - - - - - - - CMS3_k127_3530465_2 5911.EAR94633 5.186e-70 249.0 COG5253@1|root,KOG0229@2759|Eukaryota,3ZD11@5878|Ciliophora 5878|Ciliophora T Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - - - - - - - - - - MORN CMS3_k127_3534546_2 1492737.FEM08_24360 5.409e-09 69.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - ko:K07004 - - - - ko00000 - - - SLH CMS3_k127_3534546_1 283699.D172_3792 3.481e-37 166.0 COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RMPT@1236|Gammaproteobacteria 1236|Gammaproteobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS CMS3_k127_3534546_0 102125.Xen7305DRAFT_00032430 2.638e-80 308.0 COG3209@1|root,COG3209@2|Bacteria,1GJ0M@1117|Cyanobacteria,3VN4H@52604|Pleurocapsales 1117|Cyanobacteria M COG3209 Rhs family protein - - - - - - - - - - - - - CMS3_k127_3538975_5 761193.Runsl_2257 1.225e-08 65.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - - ko:K06889,ko:K09914 - - - - ko00000 - - - Cu_amine_oxidN1,Flg_new,Trypsin_2 CMS3_k127_3538975_2 1122176.KB903598_gene4683 5.252e-120 398.0 COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes 976|Bacteroidetes S integral membrane protein - - - - - - - - - - - - DUF819 CMS3_k127_3538975_4 1121904.ARBP01000012_gene1353 5.735e-47 175.0 COG1595@1|root,COG1595@2|Bacteria,4PIX2@976|Bacteroidetes,47W42@768503|Cytophagia 976|Bacteroidetes K ECF sigma factor - - - - - - - - - - - - Sigma70_r4_2 CMS3_k127_3538975_3 1317122.ATO12_20035 3.975e-47 182.0 COG3712@1|root,COG3712@2|Bacteria,4NH8I@976|Bacteroidetes,1HXP7@117743|Flavobacteriia,2YGM9@290174|Aquimarina 976|Bacteroidetes PT FecR protein - - - - - - - - - - - - DUF4974,FecR CMS3_k127_3538975_1 1121904.ARBP01000012_gene1354 3.36e-160 537.0 COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,47N17@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3538975_0 1121904.ARBP01000010_gene2359 6.028e-166 552.0 COG4733@1|root,COG4935@1|root,COG4733@2|Bacteria,COG4935@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia 976|Bacteroidetes G PFAM Fibronectin type III domain - - - - - - - - - - - - PA14,fn3 CMS3_k127_3557771_0 760192.Halhy_2973 5.865e-289 922.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_3564871_1 1218108.KB908296_gene3089 2.537e-29 134.0 COG4704@1|root,COG4704@2|Bacteria,4NGPF@976|Bacteroidetes,1HWU2@117743|Flavobacteriia 976|Bacteroidetes S Bacterial Ig-like domain - - - - - - - - - - - - Big_5 CMS3_k127_3564871_0 153721.MYP_4567 5.455e-94 335.0 COG1061@1|root,COG1112@1|root,COG1061@2|Bacteria,COG1112@2|Bacteria,4NF2S@976|Bacteroidetes,47KY5@768503|Cytophagia 976|Bacteroidetes L Superfamily I DNA and RNA - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 CMS3_k127_3572004_1 485917.Phep_2338 1.909e-90 302.0 COG0263@1|root,COG0263@2|Bacteria,4NH75@976|Bacteroidetes,1IQGG@117747|Sphingobacteriia 976|Bacteroidetes E glutamate 5-kinase proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA CMS3_k127_3572004_0 929556.Solca_2299 1.332e-107 355.0 COG0119@1|root,COG0119@2|Bacteria,4NDZH@976|Bacteroidetes,1IQRT@117747|Sphingobacteriia 976|Bacteroidetes E Hydroxymethylglutaryl-CoA lyase mvaB - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like CMS3_k127_3572004_2 760192.Halhy_2745 6.844e-64 225.0 COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,1IRUN@117747|Sphingobacteriia 976|Bacteroidetes G polysaccharide deacetylase pgdA_1 - - - - - - - - - - - Polysacc_deac_1 CMS3_k127_3572004_3 1124780.ANNU01000074_gene751 4.593e-19 89.0 COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia 976|Bacteroidetes L pfam nudix - - - - - - - - - - - - NUDIX CMS3_k127_3573110_0 1168034.FH5T_18810 2.634e-264 825.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,2FSHQ@200643|Bacteroidia 976|Bacteroidetes E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS3_k127_3573110_2 926562.Oweho_2581 3.644e-21 102.0 2BNB7@1|root,32GYU@2|Bacteria,4NQDS@976|Bacteroidetes,1ICNB@117743|Flavobacteriia,2PB7H@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3573110_1 1122621.ATZA01000002_gene1565 1.761e-72 254.0 COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IPCD@117747|Sphingobacteriia 976|Bacteroidetes I PFAM Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase CMS3_k127_3584537_2 485917.Phep_2826 2.545e-27 117.0 COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia 976|Bacteroidetes P PFAM sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_3584537_1 1121859.KB890739_gene2736 2.642e-73 265.0 COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_3584537_0 452637.Oter_4577 9.594e-86 298.0 COG0613@1|root,COG0613@2|Bacteria 2|Bacteria Q PHP domain protein - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - DUF5001 CMS3_k127_3598034_2 926549.KI421517_gene509 1.143e-40 153.0 COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,47KAK@768503|Cytophagia 976|Bacteroidetes S PFAM O-methyltransferase mdmC - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 CMS3_k127_3598034_1 1356852.N008_00420 6.203e-132 430.0 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,47M1J@768503|Cytophagia 976|Bacteroidetes L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 CMS3_k127_3598034_0 313606.M23134_05057 4.342e-305 951.0 COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,47KIY@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41,3.2.1.68 ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 CMS3_k127_3600414_4 391596.PBAL39_10691 4.922e-46 171.0 COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1IS8Q@117747|Sphingobacteriia 976|Bacteroidetes S Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_3600414_2 1121373.KB903621_gene1857 7.366e-59 209.0 COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,47RNU@768503|Cytophagia 976|Bacteroidetes O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - Redoxin CMS3_k127_3600414_3 313606.M23134_03263 1.44e-55 198.0 COG1595@1|root,COG1595@2|Bacteria,4NETF@976|Bacteroidetes,47QDK@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_3600414_7 1121904.ARBP01000007_gene3048 2.504e-14 81.0 2EJIX@1|root,33D9U@2|Bacteria,4NXKW@976|Bacteroidetes,47SWM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3600414_1 760192.Halhy_4918 8.536e-64 229.0 COG3735@1|root,COG3735@2|Bacteria,4NN4U@976|Bacteroidetes,1IT0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM GumN - - - ko:K09973 - - - - ko00000 - - - TraB CMS3_k127_3600414_0 1121895.Q765_08060 1.558e-185 609.0 COG4775@1|root,COG4775@2|Bacteria,4NFFZ@976|Bacteroidetes,1HZN6@117743|Flavobacteriia,2NTTF@237|Flavobacterium 976|Bacteroidetes M CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_3600414_5 1123277.KB893174_gene5928 4.384e-44 169.0 COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_3600414_6 56110.Oscil6304_5536 4.022e-24 117.0 COG2837@1|root,COG2837@2|Bacteria,1G5Q6@1117|Cyanobacteria,1HHN4@1150|Oscillatoriales 1117|Cyanobacteria P TIGRFAM Dyp-type peroxidase family - - - - - - - - - - - - Dyp_perox CMS3_k127_3610345_4 1121904.ARBP01000001_gene5417 4.787e-116 384.0 COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,47M3J@768503|Cytophagia 976|Bacteroidetes P TIGRFAM chromate transporter, chromate ion transporter (CHR) family - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp CMS3_k127_3610345_5 1121904.ARBP01000001_gene5673 1.904e-101 343.0 COG1283@1|root,COG1283@2|Bacteria,4NHMY@976|Bacteroidetes,47P5N@768503|Cytophagia 976|Bacteroidetes P Na+/Pi-cotransporter - - - ko:K14683 - - - - ko00000,ko02000,ko04147 2.A.58.1 - - Na_Pi_cotrans CMS3_k127_3610345_7 1123277.KB893177_gene3658 9.828e-48 178.0 COG0454@1|root,COG0456@2|Bacteria,4NU6N@976|Bacteroidetes,47VGZ@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_3610345_1 1121904.ARBP01000001_gene5684 8.27e-217 694.0 COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,47KDI@768503|Cytophagia 976|Bacteroidetes G Pyrrolo-quinoline quinone - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ CMS3_k127_3610345_2 1239962.C943_04615 1.078e-166 537.0 COG4287@1|root,COG4287@2|Bacteria,4NI0U@976|Bacteroidetes,47KB9@768503|Cytophagia 976|Bacteroidetes S PhoPQ-activated pathogenicity-related protein - - - - - - - - - - - - PhoPQ_related CMS3_k127_3610345_0 1121481.AUAS01000006_gene749 4.471e-240 750.0 COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,47M1X@768503|Cytophagia 976|Bacteroidetes E PFAM glutamine synthetase catalytic region glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N CMS3_k127_3610345_6 1121481.AUAS01000006_gene752 7.298e-73 252.0 COG0518@1|root,COG0518@2|Bacteria,4NTGJ@976|Bacteroidetes,47XUV@768503|Cytophagia 976|Bacteroidetes F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase CMS3_k127_3610345_3 1122176.KB903587_gene4472 2.241e-142 456.0 COG0714@1|root,COG0714@2|Bacteria,4P0CI@976|Bacteroidetes 976|Bacteroidetes S AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA_5 CMS3_k127_3610345_8 643867.Ftrac_0438 1.581e-40 153.0 COG3825@1|root,COG3825@2|Bacteria,4P0N6@976|Bacteroidetes,47XKY@768503|Cytophagia 976|Bacteroidetes S VWA domain containing CoxE-like protein - - - ko:K09989 - - - - ko00000 - - - - CMS3_k127_3613123_2 215803.DB30_8481 6.235e-25 121.0 COG1196@1|root,COG1196@2|Bacteria,1Q67W@1224|Proteobacteria,43EMF@68525|delta/epsilon subdivisions,2X42S@28221|Deltaproteobacteria,2YY3Z@29|Myxococcales 28221|Deltaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - CMS3_k127_3613123_0 1288963.ADIS_2100 4.504e-267 852.0 COG2010@1|root,COG2010@2|Bacteria,4NFP6@976|Bacteroidetes,47JRP@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - CBM_6,PSCyt1,PSCyt2,PSD1 CMS3_k127_3613123_1 1121859.KB890743_gene71 4.902e-249 775.0 COG3119@1|root,COG3119@2|Bacteria,4NGVK@976|Bacteroidetes,47K11@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_3613123_3 744872.Spica_2337 3.601e-23 105.0 COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,2J5A2@203691|Spirochaetes 203691|Spirochaetes T Diguanylate cyclase (GGDEF) domain - - 2.7.7.65 ko:K21022 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - GGDEF,Reg_prop,Y_Y_Y CMS3_k127_3614121_10 1086011.HJ01_00993 3.272e-19 91.0 COG2363@1|root,COG2363@2|Bacteria,4NS8F@976|Bacteroidetes,1I3ZS@117743|Flavobacteriia,2NWU8@237|Flavobacterium 976|Bacteroidetes S membrane - - - - - - - - - - - - DUF423 CMS3_k127_3614121_8 314254.OA2633_08149 2.532e-51 189.0 COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,2UAA3@28211|Alphaproteobacteria,43Y99@69657|Hyphomonadaceae 28211|Alphaproteobacteria H Nicotinamide mononucleotide transporter - - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter CMS3_k127_3614121_11 984262.SGRA_1449 9.959e-12 67.0 COG2104@1|root,COG2104@2|Bacteria 2|Bacteria H thiamine diphosphate biosynthetic process thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS CMS3_k127_3614121_0 153721.MYP_4585 0.0 1078.0 COG0422@1|root,COG0422@2|Bacteria,4NFTF@976|Bacteroidetes,47KGP@768503|Cytophagia 976|Bacteroidetes H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM CMS3_k127_3614121_9 471854.Dfer_2460 5.357e-37 147.0 COG0352@1|root,COG0352@2|Bacteria,4NNFB@976|Bacteroidetes,47PYU@768503|Cytophagia 976|Bacteroidetes H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,TMP-TENI CMS3_k127_3614121_5 313606.M23134_00087 3.026e-76 263.0 COG0351@1|root,COG0351@2|Bacteria,4NE0F@976|Bacteroidetes,47PMU@768503|Cytophagia 976|Bacteroidetes H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin CMS3_k127_3614121_6 313606.M23134_00088 2.053e-66 233.0 COG0352@1|root,COG0352@2|Bacteria,4NNFB@976|Bacteroidetes,47PYU@768503|Cytophagia 976|Bacteroidetes H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,TMP-TENI CMS3_k127_3614121_3 313606.M23134_00092 1.376e-126 409.0 COG2022@1|root,COG2022@2|Bacteria,4NDWY@976|Bacteroidetes,47JAC@768503|Cytophagia 976|Bacteroidetes H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG CMS3_k127_3614121_1 1121904.ARBP01000011_gene1509 4.506e-197 618.0 COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,47JNT@768503|Cytophagia 976|Bacteroidetes C Thiazole biosynthesis protein ThiH thiH - 4.1.99.19 ko:K03150 ko00730,ko01100,map00730,map01100 - R10246 RC01434,RC03095 ko00000,ko00001,ko01000 - - - BATS,Radical_SAM CMS3_k127_3614121_4 1168289.AJKI01000002_gene2256 1.228e-111 379.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NEKW@976|Bacteroidetes,2FM5V@200643|Bacteroidia,3XISU@558415|Marinilabiliaceae 976|Bacteroidetes M Lysin motif mltD - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS3_k127_3614121_7 1122176.KB903576_gene4905 2.79e-62 217.0 COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1ISMT@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 CMS3_k127_3614121_2 153721.MYP_972 4.975e-184 586.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47JDQ@768503|Cytophagia 976|Bacteroidetes J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS3_k127_3618426_2 1121875.KB907550_gene717 5.606e-12 76.0 COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1HYQY@117743|Flavobacteriia 976|Bacteroidetes T Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,TPR_12,TPR_8 CMS3_k127_3618426_0 1296416.JACB01000031_gene2502 6.846e-80 289.0 COG3391@1|root,COG5184@1|root,COG3391@2|Bacteria,COG5184@2|Bacteria,4NNEF@976|Bacteroidetes,1I6BT@117743|Flavobacteriia,2YK9M@290174|Aquimarina 976|Bacteroidetes DZ ig-like, plexins, transcription factors - - - - - - - - - - - - NHL,TIG CMS3_k127_3618426_1 1123278.KB893488_gene6102 5.763e-27 117.0 COG1595@1|root,COG1595@2|Bacteria,4NP91@976|Bacteroidetes,47PTK@768503|Cytophagia 976|Bacteroidetes K DNA-templated transcription, initiation - - - - - - - - - - - - - CMS3_k127_3626278_3 649349.Lbys_3546 6.292e-54 194.0 COG4232@1|root,COG4232@2|Bacteria,4PMPN@976|Bacteroidetes,47VB9@768503|Cytophagia 976|Bacteroidetes CO Protein of unknown function, DUF255 - - - - - - - - - - - - Thioredoxin_7 CMS3_k127_3626278_0 760192.Halhy_5835 1.889e-143 469.0 COG1858@1|root,COG1858@2|Bacteria,4NM2S@976|Bacteroidetes,1IVVD@117747|Sphingobacteriia 976|Bacteroidetes C PFAM Cytochrome c, class I - - - - - - - - - - - - Cytochrom_C CMS3_k127_3626278_2 1287276.X752_07555 2.387e-77 267.0 COG1082@1|root,COG1082@2|Bacteria,1N1AK@1224|Proteobacteria,2U3TU@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_3626278_1 1122132.AQYH01000003_gene3144 2.226e-132 433.0 COG0673@1|root,COG0673@2|Bacteria,1MWNK@1224|Proteobacteria,2UP2F@28211|Alphaproteobacteria,4B745@82115|Rhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_3626278_4 929562.Emtol_3974 1.996e-48 175.0 COG1946@1|root,COG1946@2|Bacteria,4NEY8@976|Bacteroidetes,47Q4R@768503|Cytophagia 976|Bacteroidetes I Acyl-CoA thioesterase tesB - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 CMS3_k127_3632011_0 760192.Halhy_6538 5.862e-268 833.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IUT7@117747|Sphingobacteriia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - Sortilin-Vps10 CMS3_k127_3632011_2 1089547.KB913013_gene3023 2.708e-71 248.0 COG1515@1|root,COG1515@2|Bacteria,4NI4J@976|Bacteroidetes,47KIS@768503|Cytophagia 976|Bacteroidetes L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA nfi - 3.1.21.7 ko:K05982 - - - - ko00000,ko01000,ko03400 - - - Endonuclease_5 CMS3_k127_3632011_3 1189612.A33Q_4322 8.078e-26 112.0 COG2172@1|root,COG2172@2|Bacteria,4NV3J@976|Bacteroidetes,47RU2@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 CMS3_k127_3632011_4 1227739.Hsw_3493 9.308e-14 76.0 COG1366@1|root,COG1366@2|Bacteria,4NVHQ@976|Bacteroidetes,47RVX@768503|Cytophagia 976|Bacteroidetes T Belongs to the anti-sigma-factor antagonist family - - - ko:K04749 - - - - ko00000,ko03021 - - - STAS CMS3_k127_3632011_1 1237149.C900_03128 6.021e-111 383.0 COG2208@1|root,COG2208@2|Bacteria,4NJMJ@976|Bacteroidetes,47JNJ@768503|Cytophagia 976|Bacteroidetes KT PFAM Stage II sporulation protein E (SpoIIE) - - - - - - - - - - - - GAF_2,SpoIIE CMS3_k127_3637414_0 929562.Emtol_0736 0.0 1394.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47JJJ@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3637414_1 929562.Emtol_0735 3.284e-296 920.0 COG1435@1|root,COG1435@2|Bacteria,4NE0A@976|Bacteroidetes,47JJB@768503|Cytophagia 976|Bacteroidetes F PFAM RagB SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_3637414_2 1122179.KB890426_gene3954 8.172e-78 265.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes 976|Bacteroidetes S PFAM ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_3638997_1 1122176.KB903554_gene3913 1.717e-92 325.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_3638997_0 1168289.AJKI01000003_gene2741 9.906e-107 350.0 COG1292@1|root,COG1292@2|Bacteria,4NEIW@976|Bacteroidetes,2FRIT@200643|Bacteroidia 976|Bacteroidetes M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT CMS3_k127_364586_0 1122176.KB903549_gene1277 0.0 1084.0 COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes 976|Bacteroidetes E Amino acid permease - - - - - - - - - - - - AA_permease CMS3_k127_364586_1 1122179.KB890423_gene2347 6.043e-29 119.0 COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1IW05@117747|Sphingobacteriia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_3655643_1 1121904.ARBP01000009_gene4264 1.415e-125 412.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3655643_0 1124780.ANNU01000071_gene1021 7.214e-178 566.0 COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia 976|Bacteroidetes G PFAM Major Facilitator Superfamily - - - ko:K08191 - - - - ko00000,ko02000 2.A.1.14.2 - - MFS_1,Sugar_tr CMS3_k127_3665172_0 1313421.JHBV01000004_gene758 5.237e-171 562.0 28JA7@1|root,2Z951@2|Bacteria,4NKY9@976|Bacteroidetes 976|Bacteroidetes S Parallel beta-helix repeats - - - - - - - - - - - - CotH CMS3_k127_3665172_3 1313421.JHBV01000004_gene759 1.786e-47 177.0 2DMQB@1|root,32SZR@2|Bacteria,4NS76@976|Bacteroidetes 976|Bacteroidetes S VTC domain - - - - - - - - - - - - VTC CMS3_k127_3665172_2 1313301.AUGC01000006_gene163 3.188e-100 332.0 COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes 976|Bacteroidetes V ABC transporter macB - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_3665172_5 1313421.JHBV01000042_gene3239 3.774e-07 59.0 2CBA9@1|root,2ZCX1@2|Bacteria,4P795@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3665172_1 1408473.JHXO01000001_gene2017 1.122e-102 363.0 COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,2FQ6Y@200643|Bacteroidia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop CMS3_k127_3665172_4 1122176.KB903565_gene3211 1.082e-08 59.0 COG1381@1|root,COG1381@2|Bacteria,4NIBQ@976|Bacteroidetes,1IS4Q@117747|Sphingobacteriia 976|Bacteroidetes L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N CMS3_k127_3666713_0 929562.Emtol_1653 7.367e-81 275.0 COG1694@1|root,COG3956@2|Bacteria,4NEA3@976|Bacteroidetes,47K4M@768503|Cytophagia 976|Bacteroidetes S PFAM MazG nucleotide pyrophosphohydrolase mazG - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - MazG CMS3_k127_3666713_2 1415780.JPOG01000001_gene2985 4.689e-55 199.0 COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria,1RXWP@1236|Gammaproteobacteria,1X7AX@135614|Xanthomonadales 135614|Xanthomonadales L NUDIX domain - - - - - - - - - - - - DUF442,NUDIX CMS3_k127_3666713_1 1121889.AUDM01000034_gene1305 5.878e-75 266.0 COG0443@1|root,COG0443@2|Bacteria,4NJFK@976|Bacteroidetes,1HYW7@117743|Flavobacteriia,2NYTX@237|Flavobacterium 976|Bacteroidetes O Hsp70 protein - - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 CMS3_k127_3666798_3 221288.JH992901_gene1730 5.588e-28 116.0 COG2913@1|root,COG2913@2|Bacteria,1G7DP@1117|Cyanobacteria,1JKBC@1189|Stigonemataceae 1117|Cyanobacteria J Protein of unknown function (DUF3574) - - - - - - - - - - - - DUF3574 CMS3_k127_3666798_1 1047013.AQSP01000104_gene1411 2.087e-121 404.0 COG5000@1|root,COG5000@2|Bacteria 2|Bacteria T phosphorelay sensor kinase activity - - - - - - - - - - - - HATPase_c,PAS_8 CMS3_k127_3666798_0 1121481.AUAS01000017_gene2476 6.508e-150 487.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_3666798_2 1121904.ARBP01000001_gene5621 1.189e-63 221.0 COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47M0A@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 N terminal domain - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_3676616_3 1121904.ARBP01000010_gene2460 1.338e-13 74.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NPTY@976|Bacteroidetes,47UE4@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS3_k127_3676616_2 945713.IALB_2909 3.025e-15 92.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Calx-beta,CarboxypepD_reg,DUF1524,Polysacc_deac_1,SLH CMS3_k127_3676616_0 762903.Pedsa_0045 1.504e-247 839.0 COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - - - - - - - - - - CARDB,CHU_C,Calx-beta,CarboxypepD_reg,DUF11,Flg_new,HYR,PKD,SLH,SdrD_B,fn3 CMS3_k127_3676616_1 1122176.KB903554_gene3790 5.447e-84 288.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_3680216_3 435591.BDI_1377 9.858e-28 114.0 COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,2FNHW@200643|Bacteroidia,22XE0@171551|Porphyromonadaceae 976|Bacteroidetes E Prephenate dehydratase pheA - 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - - PDT CMS3_k127_3680216_0 927658.AJUM01000044_gene601 1.936e-157 505.0 COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,2FN0N@200643|Bacteroidia,3XJ4N@558415|Marinilabiliaceae 976|Bacteroidetes E Aminotransferase class I and II dapL - 2.6.1.83 ko:K10206,ko:K14261 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 M00527 R07613 RC00006,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_3680216_2 1121957.ATVL01000011_gene3706 2.088e-89 302.0 COG0287@1|root,COG0287@2|Bacteria,4NEKF@976|Bacteroidetes,47N0Z@768503|Cytophagia 976|Bacteroidetes E Prephenate dehydrogenase tyrA - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH CMS3_k127_3680216_1 1237149.C900_04871 1.175e-134 438.0 COG2876@1|root,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,47K32@768503|Cytophagia 976|Bacteroidetes E chorismate mutase pheB - 5.4.99.5 ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,DAHP_synth_1 CMS3_k127_3680216_4 411684.HPDFL43_04261 1.61e-25 115.0 COG0741@1|root,COG0741@2|Bacteria,1RH42@1224|Proteobacteria,2UST0@28211|Alphaproteobacteria 28211|Alphaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - SLT CMS3_k127_3680807_0 1408473.JHXO01000008_gene2800 3.862e-250 800.0 COG1506@1|root,COG1506@2|Bacteria,4NDVD@976|Bacteroidetes,2FPXW@200643|Bacteroidia 976|Bacteroidetes E Peptidase, S9A B C family, catalytic domain protein - - - - - - - - - - - - Peptidase_S9 CMS3_k127_3680807_1 1120792.JAFV01000001_gene414 1.95e-89 302.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,2TT2Q@28211|Alphaproteobacteria,3706E@31993|Methylocystaceae 28211|Alphaproteobacteria S Aldo/keto reductase family dkgB - 1.1.1.346 ko:K06222 - - - - ko00000,ko01000 - - - Aldo_ket_red CMS3_k127_3680807_2 518766.Rmar_2142 1.001e-34 136.0 COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1FIJ7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge CMS3_k127_3685934_0 985255.APHJ01000022_gene3199 6.587e-218 692.0 COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,1HX34@117743|Flavobacteriia,2P64I@244698|Gillisia 976|Bacteroidetes CO Disulphide bond corrector protein DsbC dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 CMS3_k127_3685934_7 1121904.ARBP01000012_gene1313 1.756e-07 64.0 28H89@1|root,2Z7K8@2|Bacteria,4NEKX@976|Bacteroidetes,47M3Y@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3685934_1 926549.KI421517_gene1427 2.393e-102 340.0 COG0284@1|root,COG0284@2|Bacteria,4NE12@976|Bacteroidetes,47JHC@768503|Cytophagia 976|Bacteroidetes F Orotidine 5''-phosphate decarboxylase pyrF GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase CMS3_k127_3685934_6 1237149.C900_03633 4.806e-64 228.0 COG2162@1|root,COG2162@2|Bacteria,4NPEY@976|Bacteroidetes,47QTB@768503|Cytophagia 976|Bacteroidetes Q Belongs to the arylamine N-acetyltransferase family nat - 2.3.1.118 ko:K00675 - - - - ko00000,ko01000 - - - Acetyltransf_2 CMS3_k127_3685934_4 760192.Halhy_2599 1.177e-68 252.0 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1IT79@117747|Sphingobacteriia 976|Bacteroidetes O PFAM AhpC TSA family ccmG - - - - - - - - - - - AhpC-TSA,DUF4369 CMS3_k127_3685934_2 743722.Sph21_3108 7.356e-84 283.0 COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia 976|Bacteroidetes T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS3_k127_3685934_3 1123276.KB893279_gene2154 1.892e-73 258.0 COG5002@1|root,COG5002@2|Bacteria,4NETP@976|Bacteroidetes,47JX1@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_3685934_5 926562.Oweho_0843 2.923e-68 264.0 COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,2PBKJ@246874|Cryomorphaceae 976|Bacteroidetes O PKD domain - - - - - - - - - - - - Cleaved_Adhesin,MAM,PKD,fn3 CMS3_k127_3687906_0 926556.Echvi_1573 1.682e-192 605.0 COG4952@1|root,COG4952@2|Bacteria,4NFWW@976|Bacteroidetes,47KMM@768503|Cytophagia 976|Bacteroidetes M TIGRFAM L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype - - 5.3.1.14 ko:K01820 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01906,R02437,R06589 RC00376,RC00434,RC00516 ko00000,ko00001,ko01000 - - - - CMS3_k127_3687906_3 1123278.KB893389_gene4175 9.486e-40 152.0 COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,47RTX@768503|Cytophagia 976|Bacteroidetes P PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_3 CMS3_k127_3687906_1 236814.IX39_16340 1.167e-178 571.0 COG1070@1|root,COG1070@2|Bacteria,4NE3S@976|Bacteroidetes,1HYQ6@117743|Flavobacteriia,3ZPFQ@59732|Chryseobacterium 976|Bacteroidetes G FGGY family of carbohydrate kinases, N-terminal domain - - - - - - - - - - - - FGGY_C,FGGY_N CMS3_k127_3687906_2 661478.OP10G_0528 9.775e-73 269.0 COG1028@1|root,COG1028@2|Bacteria 661478.OP10G_0528|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - CMS3_k127_370199_0 761193.Runsl_4304 0.0 1229.0 COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47MAT@768503|Cytophagia 976|Bacteroidetes CG Cytochrome c, class I - - - ko:K08738,ko:K09992 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA CMS3_k127_370199_1 616991.JPOO01000003_gene50 3.862e-13 74.0 COG5360@1|root,COG5360@2|Bacteria 2|Bacteria S Heparinase II/III-like protein - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N CMS3_k127_3713085_1 1120965.AUBV01000013_gene1325 2.15e-190 624.0 COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia 976|Bacteroidetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge CMS3_k127_3713085_8 313606.M23134_06906 2.403e-30 121.0 COG0640@1|root,COG0640@2|Bacteria,4NS8H@976|Bacteroidetes,47R0T@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20,HTH_5 CMS3_k127_3713085_6 1121904.ARBP01000033_gene3196 2.103e-55 201.0 COG5658@1|root,COG5658@2|Bacteria,4NNCF@976|Bacteroidetes,47R6H@768503|Cytophagia 976|Bacteroidetes S SdpI/YhfL protein family - - - - - - - - - - - - DUF1648,SdpI CMS3_k127_3713085_3 926556.Echvi_2329 1.291e-167 532.0 COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,47K3S@768503|Cytophagia 976|Bacteroidetes M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd CMS3_k127_3713085_5 1124780.ANNU01000024_gene3090 2.607e-70 249.0 COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,47JUP@768503|Cytophagia 976|Bacteroidetes S PFAM von Willebrand factor type A batA - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA CMS3_k127_3713085_7 762903.Pedsa_3262 1.852e-45 173.0 COG1040@1|root,COG1040@2|Bacteria,4NNI1@976|Bacteroidetes,1IRYV@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Phosphoribosyl transferase domain comF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Pribosyltran CMS3_k127_3713085_2 1237149.C900_01718 3.268e-177 569.0 COG1055@1|root,COG1055@2|Bacteria,4NGWD@976|Bacteroidetes,47KPC@768503|Cytophagia 976|Bacteroidetes P Citrate transporter - - - - - - - - - - - - CitMHS_2 CMS3_k127_3713085_0 153721.MYP_4440 6.257e-196 647.0 COG2982@1|root,COG3064@1|root,COG2982@2|Bacteria,COG3064@2|Bacteria,4NEJQ@976|Bacteroidetes,47KBD@768503|Cytophagia 976|Bacteroidetes M AsmA-like C-terminal region - - - - - - - - - - - - AsmA,AsmA_2 CMS3_k127_3713085_4 1137281.D778_01072 3.678e-87 292.0 COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,1HX0K@117743|Flavobacteriia 976|Bacteroidetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CMS3_k127_3722664_1 1237149.C900_02606 1.498e-104 354.0 COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,47KIC@768503|Cytophagia 976|Bacteroidetes M PFAM Mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel CMS3_k127_3722664_2 1168289.AJKI01000020_gene1699 4.238e-69 242.0 COG4121@1|root,COG4121@2|Bacteria,4NE5S@976|Bacteroidetes,2FM5I@200643|Bacteroidia,3XK15@558415|Marinilabiliaceae 976|Bacteroidetes S S-adenosyl-L-methionine-dependent methyltransferase mnmC - - - - - - - - - - - Methyltransf_30 CMS3_k127_3722664_0 1123248.KB893338_gene2307 5.47e-166 548.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1INSB@117747|Sphingobacteriia 976|Bacteroidetes V TIGRFAM Acidobacterial duplicated orphan permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_3743578_1 1042376.AFPK01000067_gene825 6.389e-66 232.0 COG0800@1|root,COG0800@2|Bacteria,4NHVV@976|Bacteroidetes,1I1N6@117743|Flavobacteriia 976|Bacteroidetes G KDPG and KHG aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase CMS3_k127_3743578_2 1250232.JQNJ01000001_gene3407 1.166e-61 218.0 COG1053@1|root,COG1053@2|Bacteria,4PPUY@976|Bacteroidetes,1IKUK@117743|Flavobacteriia 976|Bacteroidetes C succinate dehydrogenase - - - - - - - - - - - - - CMS3_k127_3743578_3 1250232.JQNJ01000001_gene3408 2.149e-31 133.0 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system - - - - - - - - - - - - LytTR CMS3_k127_3743578_0 760192.Halhy_2051 1.025e-221 702.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria 2|Bacteria T PhoQ Sensor - - 4.6.1.1 ko:K01768,ko:K16923,ko:K19694 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00582,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 3.A.1.28 - - 7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_3747859_2 485918.Cpin_1672 9.849e-99 329.0 COG2227@1|root,COG2227@2|Bacteria,4NJ5I@976|Bacteroidetes,1IW68@117747|Sphingobacteriia 976|Bacteroidetes H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 CMS3_k127_3747859_1 517418.Ctha_0603 5.435e-120 395.0 COG1005@1|root,COG1005@2|Bacteria,1FF0G@1090|Chlorobi 1090|Chlorobi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh CMS3_k127_3747859_0 1313301.AUGC01000008_gene428 0.0 1121.0 COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes 976|Bacteroidetes O Belongs to the ClpA ClpB family clpC - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR CMS3_k127_3747859_4 1120951.AUBG01000014_gene3220 9.459e-35 137.0 COG1832@1|root,COG1832@2|Bacteria,4NSE8@976|Bacteroidetes,1I2XU@117743|Flavobacteriia 976|Bacteroidetes S CoA-binding protein - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 CMS3_k127_3747859_5 1270196.JCKI01000001_gene3758 2.975e-32 131.0 COG2967@1|root,COG2967@2|Bacteria,4NNRA@976|Bacteroidetes,1ISSC@117747|Sphingobacteriia 976|Bacteroidetes P protein affecting Mg2 Co2 transport apaG - - ko:K06195 - - - - ko00000 - - - DUF525 CMS3_k127_3747859_7 1112209.AHVZ01000017_gene592 2.079e-06 55.0 COG1765@1|root,COG1765@2|Bacteria,1N9KI@1224|Proteobacteria,1T13R@1236|Gammaproteobacteria,3NTI9@468|Moraxellaceae 1236|Gammaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC CMS3_k127_3747859_6 1121896.JMLU01000062_gene781 1.097e-25 109.0 COG3118@1|root,COG3118@2|Bacteria,4NSE6@976|Bacteroidetes,1I47G@117743|Flavobacteriia,2NWTE@237|Flavobacterium 976|Bacteroidetes O general stress protein ytxJ - - - - - - - - - - - DUF2847 CMS3_k127_3747859_3 929556.Solca_1231 9.378e-69 241.0 COG2265@1|root,COG2265@2|Bacteria,4PKBS@976|Bacteroidetes,1IRCR@117747|Sphingobacteriia 976|Bacteroidetes J (SAM)-dependent - - - - - - - - - - - - Cons_hypoth95,Methyltransf_15 CMS3_k127_3768880_3 1121904.ARBP01000044_gene2074 1.64e-38 151.0 2CB8S@1|root,30PE6@2|Bacteria,4NU1E@976|Bacteroidetes,47RMQ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 CMS3_k127_3768880_2 1121104.AQXH01000001_gene884 3.12e-44 165.0 COG3427@1|root,COG3427@2|Bacteria 2|Bacteria E oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - COXG,Polyketide_cyc2 CMS3_k127_3768880_5 880070.Cycma_3814 2.134e-18 95.0 COG0584@1|root,COG0584@2|Bacteria,4NMIW@976|Bacteroidetes 976|Bacteroidetes C Glycerophosphoryl diester phosphodiesterase family - - - - - - - - - - - - GDPD CMS3_k127_3768880_1 313606.M23134_01983 2.38e-73 256.0 COG1387@1|root,COG1387@2|Bacteria,4NIJU@976|Bacteroidetes,47Q20@768503|Cytophagia 976|Bacteroidetes E PHP domain - - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP CMS3_k127_3768880_0 1185876.BN8_01410 1.048e-247 792.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3768880_4 504472.Slin_3773 1.559e-34 134.0 COG1695@1|root,COG1695@2|Bacteria,4P442@976|Bacteroidetes,47V9Z@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_3770249_0 984262.SGRA_3679 7.999e-26 122.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_3782681_4 246197.MXAN_3718 7.03e-52 188.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,2YUVQ@29|Myxococcales 28221|Deltaproteobacteria Q ABC-type transport system involved in resistance to organic solvents, ATPase component - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran CMS3_k127_3782681_1 468059.AUHA01000002_gene469 8.191e-85 294.0 COG0010@1|root,COG0010@2|Bacteria,4NE5W@976|Bacteroidetes,1IQD9@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the arginase family - - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase CMS3_k127_3782681_2 700598.Niako_6634 5.801e-68 242.0 COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1IQ5S@117747|Sphingobacteriia 976|Bacteroidetes M NAD dependent epimerase dehydratase family - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase,NAD_binding_4 CMS3_k127_3782681_7 1120966.AUBU01000006_gene3462 2.944e-11 69.0 2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes,47SQD@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4890 CMS3_k127_3782681_0 1121904.ARBP01000009_gene4376 2.109e-179 569.0 COG0003@1|root,COG0003@2|Bacteria,4NNW8@976|Bacteroidetes,47TGE@768503|Cytophagia 976|Bacteroidetes D Anion-transporting ATPase - - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase CMS3_k127_3782681_6 1122176.KB903543_gene580 2.172e-30 127.0 2EMGK@1|root,33F59@2|Bacteria,4NYBS@976|Bacteroidetes,1IUEQ@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3782681_5 518766.Rmar_2154 2.424e-51 186.0 COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1FIYC@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa CMS3_k127_3782681_3 880526.KE386488_gene987 1.297e-67 235.0 COG0461@1|root,COG0461@2|Bacteria,4NEF8@976|Bacteroidetes,2FMTB@200643|Bacteroidia,22VSB@171550|Rikenellaceae 976|Bacteroidetes F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10,4.1.1.23 ko:K00762,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00051 R00965,R01870,R08231 RC00063,RC00409,RC00611 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase,Pribosyltran CMS3_k127_3783_1 1499967.BAYZ01000035_gene1060 1.968e-200 635.0 COG1032@1|root,COG1032@2|Bacteria,2NQAV@2323|unclassified Bacteria 2|Bacteria C Domain of unknown function (DUF4070) - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS3_k127_3783_4 616991.JPOO01000003_gene2353 2.357e-169 541.0 COG1921@1|root,COG1921@2|Bacteria,4NIIG@976|Bacteroidetes,1I090@117743|Flavobacteriia 976|Bacteroidetes H L-seryl-tRNA selenium transferase - - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Aminotran_5,SelA CMS3_k127_3783_6 641524.ADICYQ_5196 3.955e-59 208.0 COG0251@1|root,COG0251@2|Bacteria,4NNXK@976|Bacteroidetes,47Q05@768503|Cytophagia 976|Bacteroidetes J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP CMS3_k127_3783_2 616991.JPOO01000003_gene2354 1.323e-182 579.0 COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,1I06U@117743|Flavobacteriia 976|Bacteroidetes S Amidohydrolase family - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 CMS3_k127_3783_0 616991.JPOO01000003_gene2355 1.043e-268 837.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1HYQE@117743|Flavobacteriia,23GHM@178469|Arenibacter 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Cytochrome_CBB3,GSDH CMS3_k127_3783_5 1123248.KB893316_gene4583 8.1e-119 392.0 COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1IR5U@117747|Sphingobacteriia 976|Bacteroidetes G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL CMS3_k127_3783_3 756272.Plabr_2497 1.009e-169 546.0 COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A and related enzymes - - - - - - - - - - - - DUF4994,Sulfatase CMS3_k127_379990_1 1124780.ANNU01000044_gene539 2.227e-166 525.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,47K5S@768503|Cytophagia 976|Bacteroidetes E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N CMS3_k127_379990_2 313606.M23134_03085 2.973e-155 500.0 COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes,47K5F@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 CMS3_k127_379990_3 391596.PBAL39_20059 1.102e-76 265.0 COG3741@1|root,COG3741@2|Bacteria,4NIN9@976|Bacteroidetes 976|Bacteroidetes E N-formylglutamate deformylase - - - - - - - - - - - - FGase CMS3_k127_379990_0 313606.M23134_02397 7.915e-176 562.0 COG0402@1|root,COG0402@2|Bacteria,4NG64@976|Bacteroidetes,47UD9@768503|Cytophagia 976|Bacteroidetes F Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_379990_4 43989.cce_4773 8.689e-44 164.0 COG1403@1|root,COG1403@2|Bacteria,1G6DP@1117|Cyanobacteria,3KINB@43988|Cyanothece 1117|Cyanobacteria L SMART HNH nuclease - - - - - - - - - - - - HNH,HNH_5 CMS3_k127_379990_5 1128427.KB904821_gene1065 5.699e-13 74.0 2DPT8@1|root,333A5@2|Bacteria,1GRBS@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_3801568_4 760192.Halhy_4337 2.236e-97 329.0 COG2267@1|root,COG2267@2|Bacteria,4NKKQ@976|Bacteroidetes 976|Bacteroidetes I Alpha beta hydrolase - - - - - - - - - - - - Hydrolase_4 CMS3_k127_3801568_3 504472.Slin_2066 1.99e-102 348.0 COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,47P54@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF1624,DUF418 CMS3_k127_3801568_6 1189612.A33Q_4661 1.004e-26 123.0 COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,47XFM@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_3801568_2 1089551.KE386572_gene3187 4.467e-108 360.0 COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,2TU1A@28211|Alphaproteobacteria,4BPYR@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria M 3-beta hydroxysteroid dehydrogenase/isomerase family MA20_27225 - 1.1.1.410 ko:K22025 - - - - ko00000,ko01000 - - - Epimerase CMS3_k127_3801568_0 411154.GFO_0035 0.0 1173.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia 976|Bacteroidetes P TonB-dependent receptor plug - GO:0001871,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0004185,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0009987,GO:0010467,GO:0016020,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030246,GO:0030247,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044421,GO:0051604,GO:0070008,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:2001070 - ko:K21573 - - - - ko00000,ko02000 1.B.14.6.1 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_3801568_1 411154.GFO_0034 4.456e-238 746.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,1HWRV@117743|Flavobacteriia 976|Bacteroidetes M SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_3803164_1 1122179.KB890423_gene2317 8.603e-26 107.0 28HYV@1|root,2Z846@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_3803164_0 649349.Lbys_1863 1.397e-67 244.0 COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes 976|Bacteroidetes V Beta-lactamase class C and other penicillin binding - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase CMS3_k127_3806239_1 616991.JPOO01000001_gene4125 9.105e-179 572.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6W@976|Bacteroidetes,1I07N@117743|Flavobacteriia,23GBN@178469|Arenibacter 976|Bacteroidetes G Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS3_k127_3806239_2 1250232.JQNJ01000001_gene507 9.241e-134 436.0 COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes,1HZCR@117743|Flavobacteriia 976|Bacteroidetes G Converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim CMS3_k127_3806239_3 1121904.ARBP01000013_gene358 1.131e-117 394.0 COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia 976|Bacteroidetes S Planctomycete cytochrome C - - - - - - - - - - - - LRR_8,PSCyt1 CMS3_k127_3806239_0 1121904.ARBP01000017_gene5124 6.57e-239 742.0 COG3119@1|root,COG3119@2|Bacteria,4PKKW@976|Bacteroidetes 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_3807037_3 760192.Halhy_0989 6.177e-40 153.0 COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes,1IQGR@117747|Sphingobacteriia 976|Bacteroidetes J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d CMS3_k127_3807037_2 269798.CHU_0928 2.055e-110 369.0 COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,47KRN@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_3807037_0 1286632.P278_18360 4.05e-291 898.0 COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1HWST@117743|Flavobacteriia 976|Bacteroidetes S Carbon-nitrogen hydrolase ramA_2 - - - - - - - - - - - Acetyltransf_1,CN_hydrolase CMS3_k127_3807037_1 1237149.C900_00829 1.414e-170 543.0 COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,4NFAW@976|Bacteroidetes,47KHH@768503|Cytophagia 976|Bacteroidetes KOT Pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Glutaredoxin,Pyr_redox_2,Response_reg CMS3_k127_3832107_1 1168289.AJKI01000020_gene1660 1.732e-138 446.0 COG0330@1|root,COG0330@2|Bacteria,4NHUE@976|Bacteroidetes,2G24T@200643|Bacteroidia,3XJT5@558415|Marinilabiliaceae 976|Bacteroidetes O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 CMS3_k127_3832107_0 1121007.AUML01000007_gene2981 4.899e-177 558.0 COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes 976|Bacteroidetes O Membrane protease subunits, stomatin prohibitin homologs hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 CMS3_k127_3853080_4 1121904.ARBP01000024_gene6669 1.016e-10 66.0 COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,47K9E@768503|Cytophagia 976|Bacteroidetes S Kelch repeat - - - - - - - - - - - - He_PIG,Kelch_1,Kelch_6,Malectin,PKD CMS3_k127_3853080_3 643867.Ftrac_0597 9.783e-24 113.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - - CMS3_k127_3853080_0 980584.AFPB01000153_gene357 8.251e-181 577.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,406NJ@61432|unclassified Flavobacteriaceae 976|Bacteroidetes M MBOAT, membrane-bound O-acyltransferase family - - - - - - - - - - - - MBOAT CMS3_k127_3853080_1 1121904.ARBP01000006_gene3886 3.403e-78 268.0 COG1922@1|root,COG1922@2|Bacteria,4NJGT@976|Bacteroidetes,47NEK@768503|Cytophagia 976|Bacteroidetes M Belongs to the glycosyltransferase 26 family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB CMS3_k127_3853080_2 700598.Niako_0090 6.003e-44 162.0 COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,1IPFF@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Bacterial sugar transferase - - - ko:K03606 ko05111,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 CMS3_k127_3853448_1 1121904.ARBP01000015_gene195 6.095e-108 368.0 COG0553@1|root,COG0553@2|Bacteria,4NG6P@976|Bacteroidetes,47JVA@768503|Cytophagia 976|Bacteroidetes L PFAM Helicase conserved C-terminal domain - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - Helicase_C,SNF2_N CMS3_k127_3853448_2 1121957.ATVL01000006_gene3301 3.888e-33 141.0 2DX8D@1|root,343UE@2|Bacteria,4P6Q1@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3853448_0 1313301.AUGC01000001_gene1797 1.323e-138 449.0 COG0216@1|root,COG0216@2|Bacteria,4NF72@976|Bacteroidetes 976|Bacteroidetes J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 CMS3_k127_385716_3 1385510.N781_09600 3.551e-09 61.0 COG2322@1|root,COG2322@2|Bacteria,1V3KT@1239|Firmicutes,4HH92@91061|Bacilli,2YA4T@289201|Pontibacillus 91061|Bacilli S Protein of unknown function (DUF420) yozB - - ko:K08976 - - - - ko00000 - - - DUF420 CMS3_k127_385716_2 1408433.JHXV01000001_gene696 6.728e-10 68.0 COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,1I3NA@117743|Flavobacteriia,2PB1N@246874|Cryomorphaceae 976|Bacteroidetes S SCO1/SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC CMS3_k127_385716_1 761193.Runsl_2974 1.686e-19 93.0 COG5605@1|root,COG5605@2|Bacteria,4NTVI@976|Bacteroidetes,47R14@768503|Cytophagia 976|Bacteroidetes S Prokaryotic Cytochrome C oxidase subunit IV - - - - - - - - - - - - COX4_pro CMS3_k127_385716_0 755732.Fluta_1919 3.143e-53 199.0 COG1845@1|root,COG1845@2|Bacteria,4NDYG@976|Bacteroidetes,1HWXP@117743|Flavobacteriia,2PAN3@246874|Cryomorphaceae 976|Bacteroidetes C Heme copper-type cytochrome quinol oxidase subunit 3 coxP - 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 CMS3_k127_3857309_0 1237149.C900_00831 4.484e-70 251.0 COG3540@1|root,COG3540@2|Bacteria,4NH1W@976|Bacteroidetes,47KJQ@768503|Cytophagia 976|Bacteroidetes P PhoD-like phosphatase, N-terminal domain phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N CMS3_k127_3857309_1 485913.Krac_0867 1.093e-33 137.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity - - - - - - - - - - - - CMD CMS3_k127_3862537_3 313606.M23134_01069 2.383e-56 198.0 COG0133@1|root,COG0133@2|Bacteria,4NDWP@976|Bacteroidetes,47KSV@768503|Cytophagia 976|Bacteroidetes E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS3_k127_3862537_2 1124780.ANNU01000065_gene469 8.25e-93 312.0 COG0159@1|root,COG0159@2|Bacteria,4NE21@976|Bacteroidetes,47JYN@768503|Cytophagia 976|Bacteroidetes E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA CMS3_k127_3862537_0 1237149.C900_03306 3.374e-146 471.0 COG2876@1|root,COG2876@2|Bacteria,4NH82@976|Bacteroidetes,47KY7@768503|Cytophagia 976|Bacteroidetes E PFAM DAHP synthetase I family - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 CMS3_k127_3862537_5 880071.Fleli_2514 0.0003402 51.0 2CJYY@1|root,33ANY@2|Bacteria,4NXWC@976|Bacteroidetes,47T05@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - OMP_b-brl CMS3_k127_3862537_1 1121904.ARBP01000009_gene4348 6.814e-146 477.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,47MH5@768503|Cytophagia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_3865144_1 760192.Halhy_1182 1.319e-202 639.0 COG0493@1|root,COG0493@2|Bacteria,4NG9R@976|Bacteroidetes,1IPJB@117747|Sphingobacteriia 976|Bacteroidetes C TIGRFAM glutamate synthase, NADH NADPH, small subunit gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 CMS3_k127_3865144_0 153721.MYP_1856 0.0 1016.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,4NFKH@976|Bacteroidetes,47JB7@768503|Cytophagia 976|Bacteroidetes E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase CMS3_k127_3867863_0 266762.HQ36_01850 1.108e-90 310.0 COG0438@1|root,COG0438@2|Bacteria,4NFMB@976|Bacteroidetes,2FMJE@200643|Bacteroidia,22XBH@171551|Porphyromonadaceae 976|Bacteroidetes M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4 CMS3_k127_3867863_2 1313421.JHBV01000039_gene2658 2.382e-09 70.0 COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - B_lectin,CarboxypepD_reg,ChW,Cu-oxidase_2,DUF4842,Polysacc_deac_1,SLH CMS3_k127_3867863_1 143224.JQMD01000002_gene3799 1.946e-35 155.0 COG2133@1|root,COG2911@1|root,COG3291@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria,4PKJH@976|Bacteroidetes,1IJAY@117743|Flavobacteriia 976|Bacteroidetes G PKD domain - - - - - - - - - - - - Big_5,Malectin,PKD CMS3_k127_387108_2 929562.Emtol_1023 4.35e-77 264.0 COG2382@1|root,COG2382@2|Bacteria,4PPBB@976|Bacteroidetes 976|Bacteroidetes P Carbohydrate esterase, sialic acid-specific acetylesterase - - - - - - - - - - - - SASA CMS3_k127_387108_0 1250232.JQNJ01000001_gene2559 2.257e-224 700.0 COG4948@1|root,COG4948@2|Bacteria,4NEPP@976|Bacteroidetes,1HZ80@117743|Flavobacteriia 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_387108_1 616991.JPOO01000001_gene4555 4.636e-210 657.0 COG0673@1|root,COG0673@2|Bacteria,4NIH0@976|Bacteroidetes 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_387108_3 1121011.AUCB01000003_gene2500 3.039e-23 105.0 2BHTF@1|root,32BX3@2|Bacteria,4NRJU@976|Bacteroidetes,1IFNR@117743|Flavobacteriia,23IDU@178469|Arenibacter 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3872090_1 479434.Sthe_2689 3.117e-56 199.0 COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi,27YUC@189775|Thermomicrobia 189775|Thermomicrobia C Iron-containing alcohol dehydrogenase - - 1.1.99.24 ko:K11173 - - - - ko00000,ko01000 - - - Fe-ADH CMS3_k127_3872090_2 1121896.JMLU01000002_gene415 9.54e-49 200.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1HYG0@117743|Flavobacteriia,2NV11@237|Flavobacterium 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS3_k127_3872090_0 760192.Halhy_5814 7.955e-89 325.0 COG0497@1|root,COG1672@1|root,COG0497@2|Bacteria,COG1672@2|Bacteria 2|Bacteria L DNA recombination recN - - ko:K03631,ko:K06921,ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko02000,ko03400 3.A.1.112,8.A.1 - - SMC_N,YkyA CMS3_k127_3872090_3 1237149.C900_03415 1.252e-28 118.0 COG0454@1|root,COG0456@2|Bacteria,4NTYJ@976|Bacteroidetes,47VJU@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 CMS3_k127_3886252_5 760192.Halhy_1764 8.242e-25 111.0 COG1232@1|root,COG3064@1|root,COG1232@2|Bacteria,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - 1.4.3.4 ko:K00274,ko:K17266 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amino_oxidase CMS3_k127_3886252_6 760192.Halhy_5532 4.657e-21 108.0 2AHAR@1|root,317M3@2|Bacteria,4P8RB@976|Bacteroidetes,1IZUZ@117747|Sphingobacteriia 760192.Halhy_5532|- S IMG reference gene - - - - - - - - - - - - - CMS3_k127_3886252_3 1121875.KB907553_gene24 1.122e-43 180.0 COG0412@1|root,COG1262@1|root,COG2114@1|root,COG0412@2|Bacteria,COG1262@2|Bacteria,COG2114@2|Bacteria,4PPKM@976|Bacteroidetes 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc CMS3_k127_3886252_1 247639.MGP2080_02106 1.828e-167 544.0 COG2010@1|root,COG2010@2|Bacteria,1QX4J@1224|Proteobacteria 1224|Proteobacteria C Cytochrome c - - - - - - - - - - - - AhpC-TSA,Cu2_monoox_C,Cu2_monooxygen,Redoxin CMS3_k127_3886252_0 1121904.ARBP01000011_gene1418 5.041e-213 679.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47K06@768503|Cytophagia 976|Bacteroidetes E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS3_k127_3886252_4 1038859.AXAU01000003_gene6191 2.492e-32 135.0 2FGTF@1|root,348NS@2|Bacteria,1P2M9@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS3_k127_3886252_7 641526.ADIWIN_3825 4.758e-08 60.0 2APBA@1|root,31EDH@2|Bacteria,4NPIT@976|Bacteroidetes,1I25X@117743|Flavobacteriia 976|Bacteroidetes S Putative prokaryotic signal transducing protein - - - - - - - - - - - - DUF2007 CMS3_k127_3886252_2 1123278.KB893559_gene2970 1.274e-57 209.0 COG3395@1|root,COG3395@2|Bacteria,4NJY2@976|Bacteroidetes,47NM5@768503|Cytophagia 976|Bacteroidetes S Putative nucleotide-binding of sugar-metabolising enzyme - - 2.7.1.219,2.7.1.220 ko:K22129 - - - - ko00000,ko01000 - - - DUF1357_C,DUF1537 CMS3_k127_3899757_1 1550091.JROE01000004_gene1407 1.153e-35 141.0 COG1131@1|root,COG1131@2|Bacteria,4NN9G@976|Bacteroidetes,1IS33@117747|Sphingobacteriia 976|Bacteroidetes V ABC transporter - - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran CMS3_k127_3899757_0 1237149.C900_00754 7.238e-210 660.0 COG0624@1|root,COG0624@2|Bacteria,4NFGE@976|Bacteroidetes,47JN6@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase family M20 M25 M40 dapE - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS3_k127_3899757_3 1340434.AXVA01000020_gene1415 0.0001459 51.0 COG1434@1|root,COG1434@2|Bacteria,1VB45@1239|Firmicutes,4HMVM@91061|Bacilli,1ZI4Z@1386|Bacillus 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 CMS3_k127_3899757_2 35128.Thaps262796 9.335e-09 58.0 COG0236@1|root,KOG1748@2759|Eukaryota,2XDS0@2836|Bacillariophyta 2836|Bacillariophyta I Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - - - - - - - - - - PP-binding CMS3_k127_3920614_1 1223410.KN050846_gene254 1.504e-09 67.0 COG2834@1|root,COG2834@2|Bacteria,4NFGN@976|Bacteroidetes,1HX3V@117743|Flavobacteriia 976|Bacteroidetes M outer membrane lipoprotein carrier protein LolA lolA - - ko:K03634 - - - - ko00000 - - - LolA,LolA_2 CMS3_k127_3920614_0 929556.Solca_0800 3.195e-222 712.0 COG1674@1|root,COG1674@2|Bacteria,4NE86@976|Bacteroidetes,1INVI@117747|Sphingobacteriia 976|Bacteroidetes D DNA segregation ATPase FtsK SpoIIIE and related ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma CMS3_k127_3927857_2 485918.Cpin_1219 1.218e-20 99.0 COG2755@1|root,COG2755@2|Bacteria,4NK39@976|Bacteroidetes,1IRWS@117747|Sphingobacteriia 976|Bacteroidetes E COG2755 Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 CMS3_k127_3927857_0 1150600.ADIARSV_3176 9.887e-57 214.0 29Q0T@1|root,30AZ9@2|Bacteria,4NP77@976|Bacteroidetes,1ISFQ@117747|Sphingobacteriia 976|Bacteroidetes S Transmembrane exosortase (Exosortase_EpsH) - - - - - - - - - - - - Exosortase_EpsH CMS3_k127_3927857_1 391596.PBAL39_08681 1.794e-28 118.0 COG2304@1|root,COG2304@2|Bacteria,4NKB6@976|Bacteroidetes,1IQFS@117747|Sphingobacteriia 976|Bacteroidetes S Vault protein inter-alpha-trypsin domain - - - - - - - - - - - - VIT CMS3_k127_3934294_3 1348583.ATLH01000029_gene1593 3.019e-68 238.0 COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1HXI2@117743|Flavobacteriia,1F7WT@104264|Cellulophaga 976|Bacteroidetes K Iron dependent repressor, metal binding and dimerisation domain - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA CMS3_k127_3934294_0 880071.Fleli_1980 4.928e-244 807.0 COG3291@1|root,COG3291@2|Bacteria,4NJ47@976|Bacteroidetes,47JQU@768503|Cytophagia 976|Bacteroidetes N C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD,SBBP CMS3_k127_3934294_1 742766.HMPREF9455_03260 3.581e-190 602.0 COG0541@1|root,COG0541@2|Bacteria,4NDZ2@976|Bacteroidetes,2FNSI@200643|Bacteroidia,22WC4@171551|Porphyromonadaceae 976|Bacteroidetes U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB CMS3_k127_3934294_2 504472.Slin_1951 3.964e-71 243.0 COG1917@1|root,COG1917@2|Bacteria,4NQHB@976|Bacteroidetes,47UWK@768503|Cytophagia 976|Bacteroidetes S Cupin domain - - - - - - - - - - - - Cupin_2 CMS3_k127_3934294_5 556269.ACDQ01000009_gene1993 4.524e-16 78.0 COG0110@1|root,COG0110@2|Bacteria,1RA2T@1224|Proteobacteria,2VR8A@28216|Betaproteobacteria,477IG@75682|Oxalobacteraceae 28216|Betaproteobacteria S Hexapeptide repeat of succinyl-transferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 CMS3_k127_3934294_4 398720.MED217_06636 2.838e-37 141.0 COG3408@1|root,COG3408@2|Bacteria,4NHHR@976|Bacteroidetes,1I003@117743|Flavobacteriia 976|Bacteroidetes G Alpha-L-rhamnosidase N-terminal domain - - - - - - - - - - - - Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N CMS3_k127_3935341_4 199310.c4363 4.127e-05 47.0 28VP7@1|root,2ZHR6@2|Bacteria,1P8M3@1224|Proteobacteria,1SVC4@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_3935341_1 743722.Sph21_4078 2.818e-41 162.0 COG3206@1|root,COG3206@2|Bacteria,4NP00@976|Bacteroidetes,1ISIK@117747|Sphingobacteriia 976|Bacteroidetes M Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 CMS3_k127_3935341_0 1150600.ADIARSV_3941 2.379e-188 601.0 COG1233@1|root,COG1233@2|Bacteria,4NG7V@976|Bacteroidetes,1IR1U@117747|Sphingobacteriia 976|Bacteroidetes Q Flavin containing amine oxidoreductase crtI - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase CMS3_k127_3935341_2 1279009.ADICEAN_03434 3.317e-26 109.0 COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,47R5P@768503|Cytophagia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL28 family rpmB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 CMS3_k127_3935341_3 242619.PG_1837 2.241e-11 76.0 COG1974@1|root,COG1974@2|Bacteria,4NYWJ@976|Bacteroidetes,2FWS6@200643|Bacteroidia 976|Bacteroidetes KT Cleaved Adhesin Domain hagA - - - - - - - - - - - Cleaved_Adhesin,DUF2436 CMS3_k127_394038_3 1250005.PHEL85_1697 4.748e-07 56.0 COG4659@1|root,COG4659@2|Bacteria,4NQKH@976|Bacteroidetes,1IAXX@117743|Flavobacteriia 976|Bacteroidetes U Part of a membrane complex involved in electron transport rnfG - - ko:K03612 - - - - ko00000 - - - FMN_bind CMS3_k127_394038_1 1049564.TevJSym_aq00700 2.95e-107 357.0 COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE CMS3_k127_394038_0 519989.ECTPHS_08973 9.785e-129 425.0 COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WXET@135613|Chromatiales 135613|Chromatiales C Part of a membrane complex involved in electron transport - - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_8,RnfC_N,SLBB CMS3_k127_394038_2 1049564.TevJSym_aq00810 1.399e-62 237.0 COG0674@1|root,COG1013@1|root,COG1144@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1144@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria 2|Bacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin forE - 1.2.7.1 ko:K00171,ko:K00172,ko:K02573,ko:K03737,ko:K13795,ko:K18930 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00173,M00307,M00374,M00620 R01196,R01199,R08034,R10866 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - CCG,Fer4,Fer4_4,Fer4_6,Fer4_9,Nitroreductase,PFOR_II,POR,POR_N,TPP_enzyme_C CMS3_k127_3950942_4 118161.KB235922_gene4646 4.575e-40 153.0 COG1028@1|root,COG1028@2|Bacteria,1G2ZD@1117|Cyanobacteria,3VM8E@52604|Pleurocapsales 1117|Cyanobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CMS3_k127_3950942_2 1096930.L284_09065 2.624e-81 287.0 COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2U8DJ@28211|Alphaproteobacteria,2K102@204457|Sphingomonadales 204457|Sphingomonadales G MFS/sugar transport protein - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 CMS3_k127_3950942_3 1150600.ADIARSV_0224 1.854e-64 226.0 COG2065@1|root,COG2065@2|Bacteria,4NFI1@976|Bacteroidetes,1IQWE@117747|Sphingobacteriia 976|Bacteroidetes F uracil phosphoribosyltransferase pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran CMS3_k127_3950942_0 1122621.ATZA01000015_gene3656 2.605e-149 477.0 COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,1IP8Y@117747|Sphingobacteriia 976|Bacteroidetes F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N CMS3_k127_3950942_1 1168034.FH5T_01210 2.729e-83 295.0 COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia 976|Bacteroidetes S Permease, YjgP YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ CMS3_k127_3951377_0 927677.ALVU02000001_gene2206 4.737e-155 515.0 COG5434@1|root,COG5434@2|Bacteria,1G0JG@1117|Cyanobacteria 1117|Cyanobacteria M Pectate lyase superfamily protein - - - - - - - - - - - - DUF1349,DUF4347,Pectate_lyase_3 CMS3_k127_3951377_1 234267.Acid_1471 5.321e-50 188.0 COG0491@1|root,COG0491@2|Bacteria,3Y83W@57723|Acidobacteria 57723|Acidobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_3951377_2 1279009.ADICEAN_03629 2.564e-41 156.0 COG0702@1|root,COG0702@2|Bacteria 2|Bacteria GM epimerase - - 1.23.1.1,1.23.1.2,1.23.1.3,1.23.1.4 ko:K21568 - - - - ko00000,ko01000 - - - NAD_binding_10,NmrA CMS3_k127_3955645_0 109760.SPPG_04804T0 3.507e-75 259.0 COG1063@1|root,KOG0024@2759|Eukaryota,38I2Z@33154|Opisthokonta,3NXYU@4751|Fungi 4751|Fungi Q Dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS3_k127_3955645_2 1279009.ADICEAN_03131 2.504e-10 70.0 2BUXY@1|root,32QAA@2|Bacteria,4NPCP@976|Bacteroidetes,47WCW@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3955645_1 1227739.Hsw_2278 1.791e-14 82.0 COG3307@1|root,COG3307@2|Bacteria,4NZFV@976|Bacteroidetes,47SUE@768503|Cytophagia 976|Bacteroidetes M O-Antigen ligase - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C CMS3_k127_3964128_0 1122179.KB890434_gene834 7.78e-182 574.0 COG1506@1|root,COG1506@2|Bacteria,4NE2Q@976|Bacteroidetes,1IP3R@117747|Sphingobacteriia 976|Bacteroidetes E Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - - - - - - - - - - DPPIV_N,Peptidase_S9 CMS3_k127_3964128_8 1122179.KB890459_gene980 1.01e-41 158.0 COG0454@1|root,COG0456@2|Bacteria,4NURB@976|Bacteroidetes 976|Bacteroidetes K DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_3964128_1 391603.FBALC1_05263 1.284e-139 454.0 COG0451@1|root,COG0451@2|Bacteria,4NX6A@976|Bacteroidetes,1IAM7@117743|Flavobacteriia 976|Bacteroidetes GM ADP-glyceromanno-heptose 6-epimerase activity - - - - - - - - - - - - Epimerase CMS3_k127_3964128_4 41431.PCC8801_0005 5.064e-79 271.0 COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece 1117|Cyanobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - 2.1.1.334 ko:K21310 ko00920,map00920 - R11546 RC02653 ko00000,ko00001,ko01000 - - - NnrU,PEMT CMS3_k127_3964128_2 1123277.KB893174_gene5927 8.566e-117 413.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase,Reg_prop,Y_Y_Y CMS3_k127_3964128_6 1123277.KB893174_gene5928 1.647e-63 225.0 COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_3964128_9 760192.Halhy_3154 2.247e-25 111.0 COG1672@1|root,COG1672@2|Bacteria,4NIJ4@976|Bacteroidetes,1IX5K@117747|Sphingobacteriia 976|Bacteroidetes S Predicted AAA-ATPase - - - - - - - - - - - - AAA-ATPase_like,PDDEXK_9 CMS3_k127_3964128_3 1385935.N836_31165 4.712e-94 314.0 COG4912@1|root,COG4912@2|Bacteria,1G63N@1117|Cyanobacteria,1HFFN@1150|Oscillatoriales 1117|Cyanobacteria L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation CMS3_k127_3964128_7 313606.M23134_00875 5.546e-58 225.0 COG4249@1|root,COG4249@2|Bacteria,4NSC3@976|Bacteroidetes,47S66@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14,TPR_2 CMS3_k127_3964128_5 1121904.ARBP01000001_gene5655 6.783e-69 238.0 COG0431@1|root,COG0431@2|Bacteria,4NNMA@976|Bacteroidetes,47V9A@768503|Cytophagia 976|Bacteroidetes S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red CMS3_k127_3969102_1 1122918.KB907280_gene254 3.387e-75 271.0 COG3934@1|root,COG3934@2|Bacteria,1VUFZ@1239|Firmicutes 1239|Firmicutes G Domain of unknown function (DUF5060) - - - - - - - - - - - - DUF5060 CMS3_k127_3969102_2 1123276.KB893301_gene4289 6.703e-30 119.0 COG2442@1|root,COG2442@2|Bacteria,4NVK1@976|Bacteroidetes,47SGW@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF433) - - - - - - - - - - - - DUF433 CMS3_k127_3969102_3 1111730.ATTM01000001_gene1463 3.403e-21 96.0 COG4634@1|root,COG4634@2|Bacteria,4NVZ3@976|Bacteroidetes,1IIE6@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3969102_0 1122176.KB903554_gene3790 1.415e-183 593.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_3969129_0 927658.AJUM01000010_gene1345 2.812e-124 409.0 COG0116@1|root,COG0116@2|Bacteria,4NFJM@976|Bacteroidetes,2FMNN@200643|Bacteroidia 976|Bacteroidetes L Belongs to the methyltransferase superfamily rlmL - - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 CMS3_k127_3975467_1 643867.Ftrac_1546 1.731e-74 265.0 COG3857@1|root,COG3857@2|Bacteria,4PKEH@976|Bacteroidetes,47YDH@768503|Cytophagia 976|Bacteroidetes L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - Exonuc_V_gamma,PDDEXK_1 CMS3_k127_3975467_0 313606.M23134_07479 0.0 1467.0 COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,47MEM@768503|Cytophagia 976|Bacteroidetes S Alpha-2-macroglobulin family - - - - - - - - - - - - A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug CMS3_k127_3975467_2 1313421.JHBV01000044_gene2952 1.042e-34 139.0 COG2373@1|root,COG2373@2|Bacteria,4NED2@976|Bacteroidetes,1IQPG@117747|Sphingobacteriia 976|Bacteroidetes S COG2373 Large extracellular alpha-helical protein - - - - - - - - - - - - A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug CMS3_k127_3981814_2 1250005.PHEL85_0419 1.219e-35 140.0 COG3874@1|root,COG3874@2|Bacteria,4NTIV@976|Bacteroidetes,1I31B@117743|Flavobacteriia,3VXA3@52959|Polaribacter 976|Bacteroidetes S Sporulation protein YtfJ (Spore_YtfJ) - - - - - - - - - - - - Spore_YtfJ CMS3_k127_3981814_3 760192.Halhy_1957 9.863e-15 81.0 2C8EV@1|root,32RM1@2|Bacteria,4NU8V@976|Bacteroidetes,1IZYA@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_3981814_0 246197.MXAN_2150 5.225e-160 527.0 COG1680@1|root,COG1680@2|Bacteria,1R62E@1224|Proteobacteria 1224|Proteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_3981814_1 1313421.JHBV01000019_gene5344 7.902e-52 198.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_3991941_0 313606.M23134_02529 0.0 1329.0 COG1538@1|root,COG2351@1|root,COG3409@1|root,COG1538@2|Bacteria,COG2351@2|Bacteria,COG3409@2|Bacteria,4NJ4W@976|Bacteroidetes,47K3F@768503|Cytophagia 976|Bacteroidetes M Salmonella virulence plasmid 28.1kDa A protein - - - - - - - - - - - - Hemopexin,VRP1 CMS3_k127_3993623_1 1122621.ATZA01000051_gene2841 4.38e-96 320.0 COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes,1IP7E@117747|Sphingobacteriia 976|Bacteroidetes S COGs COG3533 conserved - - - ko:K09955 - - - - ko00000 - - - DUF4986,Glyco_hydro_127 CMS3_k127_3993623_2 671143.DAMO_1347 1.068e-10 68.0 COG5485@1|root,COG5485@2|Bacteria,2NRTW@2323|unclassified Bacteria 2|Bacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - SnoaL CMS3_k127_3993623_0 761193.Runsl_1968 2.506e-135 440.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_3999449_0 471854.Dfer_1695 1.642e-87 295.0 COG1291@1|root,COG1291@2|Bacteria,4NTWT@976|Bacteroidetes 976|Bacteroidetes U MotA/TolQ/ExbB proton channel family - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB CMS3_k127_4000413_0 760192.Halhy_5448 2.227e-147 470.0 COG2227@1|root,COG2227@2|Bacteria,4NK04@976|Bacteroidetes 976|Bacteroidetes H C-methyltransferase C-terminal domain - - - - - - - - - - - - Methyltransf_13,Methyltransf_14,Methyltransf_23 CMS3_k127_4000413_1 760192.Halhy_5449 2.253e-138 443.0 COG1208@1|root,COG1208@2|Bacteria,4NG3V@976|Bacteroidetes,1IRC1@117747|Sphingobacteriia 976|Bacteroidetes JM COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - - 2.7.7.33 ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 - R00956 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase CMS3_k127_4000413_2 760192.Halhy_5451 3.094e-54 194.0 COG2120@1|root,COG2120@2|Bacteria,4NN16@976|Bacteroidetes 976|Bacteroidetes S PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase - - - - - - - - - - - - PIG-L CMS3_k127_4005792_1 1168034.FH5T_00895 1.39e-154 499.0 COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,2FR3P@200643|Bacteroidia 976|Bacteroidetes I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase CMS3_k127_4005792_2 926549.KI421517_gene2694 1.766e-112 373.0 COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia 976|Bacteroidetes S RelA SpoT domain protein - - - - - - - - - - - - GTA_TIM CMS3_k127_4005792_0 313596.RB2501_00496 0.0 1167.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HWVV@117743|Flavobacteriia 976|Bacteroidetes G hydrolase, family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_4005792_7 926556.Echvi_3703 1.449e-07 62.0 COG0457@1|root,COG0457@2|Bacteria,4NYDQ@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_4005792_5 1121104.AQXH01000001_gene1729 7.948e-47 181.0 COG2304@1|root,COG2304@2|Bacteria,4NF7Y@976|Bacteroidetes,1IR1C@117747|Sphingobacteriia 976|Bacteroidetes S von Willebrand factor, type A batB - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 CMS3_k127_4005792_3 1313421.JHBV01000030_gene2256 6.015e-76 271.0 COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia 976|Bacteroidetes EP PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N CMS3_k127_4005792_4 1122176.KB903539_gene1332 1.377e-74 268.0 COG0601@1|root,COG0601@2|Bacteria,4NGIJ@976|Bacteroidetes,1IRI6@117747|Sphingobacteriia 976|Bacteroidetes P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 CMS3_k127_4005792_6 1218108.KB908301_gene2434 5.937e-08 54.0 2EMJ4@1|root,33F7P@2|Bacteria,4NYXT@976|Bacteroidetes,1I5IS@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4007002_1 1121101.HMPREF1532_04022 2.631e-07 55.0 COG1470@1|root,COG1470@2|Bacteria,4NFPN@976|Bacteroidetes,2FMUB@200643|Bacteroidia,4AKJI@815|Bacteroidaceae 976|Bacteroidetes S Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_4007002_0 673862.BABL1_1000 3.734e-11 74.0 COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria 1224|Proteobacteria M 6-phosphogluconolactonase activity - - - - - - - - - - - - ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS CMS3_k127_4028351_1 1168289.AJKI01000003_gene2741 8.685e-103 340.0 COG1292@1|root,COG1292@2|Bacteria,4NEIW@976|Bacteroidetes,2FRIT@200643|Bacteroidia 976|Bacteroidetes M Belongs to the BCCT transporter (TC 2.A.15) family - - - ko:K02168 - - - - ko00000,ko02000 2.A.15.1.3,2.A.15.1.4 - - BCCT CMS3_k127_4028351_2 1168034.FH5T_14010 1.345e-42 162.0 COG1846@1|root,COG1846@2|Bacteria,4NRNH@976|Bacteroidetes 976|Bacteroidetes K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR CMS3_k127_4028351_0 616991.JPOO01000003_gene1758 3.545e-233 736.0 COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,1HZGN@117743|Flavobacteriia,23HSZ@178469|Arenibacter 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_4037597_0 880073.Calab_0636 7.515e-60 229.0 COG2911@1|root,COG3227@1|root,COG2911@2|Bacteria,COG3227@2|Bacteria 2|Bacteria E Zinc metalloprotease (Elastase) - - - ko:K20274 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - FTP,PepSY,Peptidase_M36,Peptidase_M4_C CMS3_k127_4037597_1 1462527.CCDM010000002_gene890 1.231e-36 143.0 COG0494@1|root,COG0494@2|Bacteria,1VPHI@1239|Firmicutes,4HR9R@91061|Bacilli 91061|Bacilli L nUDIX hydrolase - - - - - - - - - - - - NUDIX CMS3_k127_4037597_3 1168034.FH5T_19715 7.655e-26 110.0 COG0724@1|root,COG0724@2|Bacteria,4NSXX@976|Bacteroidetes,2FUB9@200643|Bacteroidia 976|Bacteroidetes S COG COG0724 RNA-binding proteins (RRM domain) - - - - - - - - - - - - RRM_1 CMS3_k127_4037597_4 395493.BegalDRAFT_1112 7.732e-07 52.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T4BF@1236|Gammaproteobacteria 1224|Proteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase chiS - 2.7.13.3 ko:K07711,ko:K19694 ko02020,ko02024,map02020,map02024 M00502 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HAMP,HATPase_c,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg,Y_Y_Y CMS3_k127_4037597_2 755732.Fluta_1564 1.732e-26 113.0 2DKFZ@1|root,309D6@2|Bacteria,4PK7J@976|Bacteroidetes,1IFCY@117743|Flavobacteriia,2PB0S@246874|Cryomorphaceae 976|Bacteroidetes S Domain of unknown function (DUF4382) - - - - - - - - - - - - DUF4382 CMS3_k127_4043371_0 1237149.C900_01975 5.009e-223 705.0 COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,47KUQ@768503|Cytophagia 976|Bacteroidetes E PFAM Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS3_k127_4043371_2 1453500.AT05_07840 1.558e-17 93.0 2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia 976|Bacteroidetes S Reeler domain - - - - - - - - - - - - Reeler CMS3_k127_4043371_1 1237149.C900_03649 1.134e-58 210.0 COG2203@1|root,COG3292@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NK8Q@976|Bacteroidetes,47M6U@768503|Cytophagia 976|Bacteroidetes KT PFAM Y_Y_Y domain - - - - - - - - - - - - GAF_2,HATPase_c,HTH_18,HisKA,HisKA_2,Reg_prop,Response_reg,SpoIIE,Y_Y_Y CMS3_k127_4051859_1 929562.Emtol_3529 1.444e-06 61.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS3_k127_4051859_0 1000565.METUNv1_01833 2.243e-09 65.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - C5-epim_C,Wzy_C CMS3_k127_4082632_2 471854.Dfer_1695 8.149e-86 291.0 COG1291@1|root,COG1291@2|Bacteria,4NTWT@976|Bacteroidetes 976|Bacteroidetes U MotA/TolQ/ExbB proton channel family - - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB CMS3_k127_4082632_1 102129.Lepto7375DRAFT_3753 8.499e-220 697.0 28H5N@1|root,2Z7I8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4082632_0 272134.KB731324_gene1542 2e-323 1049.0 COG1579@1|root,COG1579@2|Bacteria 2|Bacteria - - oppA - 2.1.1.80,3.1.1.61 ko:K13582,ko:K13924,ko:K15580 ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112 M00439,M00506 - - ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - CheB_methylest,CheR,CheR_N,DUF4349,Flg_new,HWE_HK,Methyltransf_21,PAS_10,SBP_bac_5 CMS3_k127_4086094_1 518766.Rmar_2162 3.217e-173 560.0 COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,4NH3P@976|Bacteroidetes,1FIQ9@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3 CMS3_k127_4086094_0 926549.KI421517_gene76 4.821e-278 872.0 COG4993@1|root,COG4993@2|Bacteria,4NINH@976|Bacteroidetes,47MZW@768503|Cytophagia 976|Bacteroidetes G PQQ-like domain - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 CMS3_k127_4086094_2 575590.HMPREF0156_01546 9.877e-88 299.0 COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes 976|Bacteroidetes J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CMS3_k127_4086094_3 984262.SGRA_0487 1.62e-44 171.0 COG1386@1|root,COG1386@2|Bacteria,4NPG3@976|Bacteroidetes,1IS83@117747|Sphingobacteriia 976|Bacteroidetes D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB CMS3_k127_4086094_4 236814.IX39_15635 7.798e-24 107.0 2CG1Y@1|root,333IH@2|Bacteria,4NVMK@976|Bacteroidetes,1I9TA@117743|Flavobacteriia,3ZRTE@59732|Chryseobacterium 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 CMS3_k127_4087360_1 489825.LYNGBM3L_27060 7.825e-18 92.0 2EG4Q@1|root,339WQ@2|Bacteria,1GH2Z@1117|Cyanobacteria,1HGVT@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_4087360_0 1121091.AUMP01000017_gene916 1.054e-108 363.0 COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli 91061|Bacilli N Protein conserved in bacteria yngK - - - - - - - - - - - Big_2,Cu_amine_oxidN1,GHL10 CMS3_k127_4094805_0 313603.FB2170_09306 1.289e-219 684.0 COG4948@1|root,COG4948@2|Bacteria,4PKP3@976|Bacteroidetes 976|Bacteroidetes M COG NOG06228 non supervised orthologous group - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - GH97_C,GH97_N,Glyco_hydro_97 CMS3_k127_4094805_1 1121011.AUCB01000039_gene945 8.45e-185 588.0 COG1073@1|root,COG1073@2|Bacteria,4PKM0@976|Bacteroidetes,1IJCB@117743|Flavobacteriia 976|Bacteroidetes S alpha beta - - - - - - - - - - - - Lipase_GDSL_2,Peptidase_S9 CMS3_k127_4100807_2 391596.PBAL39_04713 4.728e-39 147.0 COG0537@1|root,COG0537@2|Bacteria,4NQ4X@976|Bacteroidetes,1ISWH@117747|Sphingobacteriia 976|Bacteroidetes FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hinT - - ko:K02503 - - - - ko00000,ko04147 - - - HIT CMS3_k127_4100807_4 1313421.JHBV01000035_gene2544 6.068e-23 114.0 COG4935@1|root,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - P_proprotein,SprB CMS3_k127_4100807_0 1538644.KO02_02510 3.981e-63 223.0 COG0817@1|root,COG0817@2|Bacteria,4NDV6@976|Bacteroidetes,1ISJU@117747|Sphingobacteriia 976|Bacteroidetes L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC CMS3_k127_4100807_1 1313421.JHBV01000023_gene5168 1.043e-61 226.0 COG1215@1|root,COG1215@2|Bacteria,4NG9C@976|Bacteroidetes,1IPRP@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_4100807_3 1408813.AYMG01000014_gene1591 1.676e-35 143.0 COG1173@1|root,COG1173@2|Bacteria,4NGTQ@976|Bacteroidetes,1IQI5@117747|Sphingobacteriia 976|Bacteroidetes EP PFAM Binding-protein-dependent transport system inner membrane component dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N CMS3_k127_4104703_1 616991.JPOO01000003_gene2297 2.454e-101 335.0 COG0767@1|root,COG0767@2|Bacteria,4NF7X@976|Bacteroidetes,1HX62@117743|Flavobacteriia,23H53@178469|Arenibacter 976|Bacteroidetes Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE CMS3_k127_4104703_2 1237149.C900_03831 8.221e-96 319.0 COG1127@1|root,COG1127@2|Bacteria,4NETJ@976|Bacteroidetes,47NIJ@768503|Cytophagia 976|Bacteroidetes Q ABC transporter - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran CMS3_k127_4104703_3 1237149.C900_03830 2.496e-67 241.0 COG1463@1|root,COG1463@2|Bacteria,4NGHE@976|Bacteroidetes,47T9B@768503|Cytophagia 976|Bacteroidetes Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD CMS3_k127_4104703_0 670292.JH26_02420 1.205e-103 357.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Adenylate cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,TPR_2,TPR_8 CMS3_k127_4120870_0 760192.Halhy_6353 1.556e-303 955.0 COG0464@1|root,COG0464@2|Bacteria,4NJBD@976|Bacteroidetes,1ISED@117747|Sphingobacteriia 976|Bacteroidetes O of the AAA class - - - - - - - - - - - - AAA CMS3_k127_4120870_1 279714.FuraDRAFT_2808 1.683e-25 113.0 COG0824@1|root,COG0824@2|Bacteria,1REIH@1224|Proteobacteria,2VTNS@28216|Betaproteobacteria,2KRST@206351|Neisseriales 206351|Neisseriales S Acyl-CoA thioester hydrolase, YbgC YbaW family - - - ko:K12500 - - - - ko00000,ko01000,ko01004 - - - 4HBT,4HBT_2 CMS3_k127_4123806_2 1288963.ADIS_1966 4.91e-91 304.0 COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,47JRY@768503|Cytophagia 976|Bacteroidetes E PFAM Serine dehydratase alpha chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta CMS3_k127_4123806_4 886379.AEWI01000026_gene437 1.63e-52 189.0 COG0636@1|root,COG0636@2|Bacteria,4NPFU@976|Bacteroidetes,2FSVQ@200643|Bacteroidia,3XK1U@558415|Marinilabiliaceae 976|Bacteroidetes C ATP synthase subunit C ntpK - - ko:K02124 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_C CMS3_k127_4123806_1 886379.AEWI01000026_gene436 3.091e-124 419.0 COG1269@1|root,COG1269@2|Bacteria,4NGJ9@976|Bacteroidetes,2FMC6@200643|Bacteroidia,3XIKM@558415|Marinilabiliaceae 976|Bacteroidetes C V-type ATPase 116kDa subunit family - - - ko:K02123 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - V_ATPase_I CMS3_k127_4123806_3 1168289.AJKI01000044_gene87 5.87e-62 218.0 COG1394@1|root,COG1394@2|Bacteria,4NMF2@976|Bacteroidetes,2FM0M@200643|Bacteroidia,3XIVG@558415|Marinilabiliaceae 976|Bacteroidetes C ATP synthase subunit D - - - ko:K02120 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_D CMS3_k127_4123806_0 709991.Odosp_1935 1.39e-225 704.0 COG1156@1|root,COG1156@2|Bacteria,4NIH8@976|Bacteroidetes,2FNPF@200643|Bacteroidia,22WY4@171551|Porphyromonadaceae 976|Bacteroidetes C the B subunit is part of the catalytic core of the ATP synthase complex ntpB - - ko:K02118 ko00190,ko01100,map00190,map01100 M00159 - - ko00000,ko00001,ko00002 3.A.2.2,3.A.2.3 - - ATP-synt_ab,ATP-synt_ab_N CMS3_k127_4129861_2 869213.JCM21142_41639 2.857e-57 205.0 COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,47NM0@768503|Cytophagia 976|Bacteroidetes E PFAM Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT CMS3_k127_4129861_0 1223410.KN050846_gene1208 2.935e-85 300.0 COG3250@1|root,COG3250@2|Bacteria,4P3W0@976|Bacteroidetes,1I918@117743|Flavobacteriia 976|Bacteroidetes G Vitamin K-dependent gamma-carboxylase - - - - - - - - - - - - VKG_Carbox CMS3_k127_4129861_3 1237149.C900_05501 2.091e-09 60.0 COG0665@1|root,COG0665@2|Bacteria,4NEEY@976|Bacteroidetes,47JUY@768503|Cytophagia 976|Bacteroidetes E Glycine D-amino acid oxidase (deaminating) - - - - - - - - - - - - DAO CMS3_k127_4129861_1 984262.SGRA_3314 1.162e-64 246.0 COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes 976|Bacteroidetes S COG3291 FOG PKD repeat - - - - - - - - - - - - CHU_C,PKD CMS3_k127_4130145_5 1121287.AUMU01000012_gene2429 1.032e-30 121.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,1HX6F@117743|Flavobacteriia,3ZQBI@59732|Chryseobacterium 976|Bacteroidetes P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N CMS3_k127_4130145_1 649638.Trad_2740 2.345e-158 524.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1WKZM@1297|Deinococcus-Thermus 2|Bacteria I 3-hydroxyacyl-CoA dehydrogenase fadJ GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 ko:K00074,ko:K01782,ko:K07516 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - iECABU_c1320.ECABU_c26730,iETEC_1333.ETEC_2476,iEcE24377_1341.EcE24377A_2637,ic_1306.c2886 3HCDH,3HCDH_N,ECH_1 CMS3_k127_4130145_3 1041826.FCOL_00775 4.321e-91 311.0 COG0584@1|root,COG0584@2|Bacteria,4NGI1@976|Bacteroidetes,1I0PI@117743|Flavobacteriia,2NWFQ@237|Flavobacterium 976|Bacteroidetes C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,Phytase-like CMS3_k127_4130145_6 1123242.JH636434_gene4457 2.549e-12 80.0 COG3613@1|root,COG3613@2|Bacteria,2J12J@203682|Planctomycetes 203682|Planctomycetes F nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - - CMS3_k127_4130145_2 522373.Smlt0211 1.432e-114 381.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1X9GF@135614|Xanthomonadales 135614|Xanthomonadales F Belongs to the D-alanine--D-alanine ligase family ddlA - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N CMS3_k127_4130145_4 153721.MYP_45 9.228e-76 259.0 COG0353@1|root,COG0353@2|Bacteria,4NEWI@976|Bacteroidetes,47JZK@768503|Cytophagia 976|Bacteroidetes L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 CMS3_k127_4130145_0 1168034.FH5T_21745 8.543e-167 546.0 COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia 976|Bacteroidetes S Glycosyltransferase, group 2 family protein wbbL - - ko:K07011 - - - - ko00000 - - - CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_4133882_2 880070.Cycma_1982 2.916e-193 615.0 COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,47N6U@768503|Cytophagia 976|Bacteroidetes H TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_4133882_1 1121904.ARBP01000008_gene3440 2.839e-208 659.0 COG4198@1|root,COG4198@2|Bacteria,4NI11@976|Bacteroidetes,47NFX@768503|Cytophagia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like CMS3_k127_4133882_0 1121012.AUKX01000047_gene2055 0.0 1188.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,23FKS@178469|Arenibacter 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_4133882_3 929556.Solca_3741 3.286e-08 64.0 COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,1IPR2@117747|Sphingobacteriia 976|Bacteroidetes NU PFAM Tetratricopeptide - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_8 CMS3_k127_414475_2 1122179.KB890416_gene2657 4.122e-37 147.0 COG0671@1|root,COG0671@2|Bacteria,4NMQW@976|Bacteroidetes 976|Bacteroidetes I Acid phosphatase homologues - - - - - - - - - - - - PAP2 CMS3_k127_414475_1 1121904.ARBP01000003_gene6331 9.24e-56 220.0 COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47N72@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_414475_0 1396418.BATQ01000186_gene2161 2.355e-135 456.0 COG3401@1|root,COG3401@2|Bacteria 2|Bacteria Q FG-GAP repeat protein - - - - - - - - - - - - Laminin_G_3 CMS3_k127_4145762_1 1120968.AUBX01000010_gene1225 5.602e-42 155.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47K5R@768503|Cytophagia 976|Bacteroidetes P TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4145762_0 1120968.AUBX01000010_gene1226 7.817e-259 808.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,47TPH@768503|Cytophagia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_4157363_2 1122176.KB903536_gene1855 3.966e-41 172.0 COG0457@1|root,COG0457@2|Bacteria,4NGS0@976|Bacteroidetes,1IXQC@117747|Sphingobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_12 CMS3_k127_4157363_1 1121904.ARBP01000008_gene3392 3.111e-183 604.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4157363_3 1123277.KB893195_gene5684 1.561e-36 140.0 COG1695@1|root,COG1695@2|Bacteria,4P6G7@976|Bacteroidetes,47VZ7@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_4157363_0 1121373.KB903632_gene433 2.458e-310 968.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,47JHD@768503|Cytophagia 976|Bacteroidetes G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate ppsA - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N CMS3_k127_4161293_3 1121373.KB903625_gene3157 1.055e-21 102.0 COG2373@1|root,COG2373@2|Bacteria,4NEW9@976|Bacteroidetes,47MDC@768503|Cytophagia 976|Bacteroidetes S Alpha-2-Macroglobulin - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl CMS3_k127_4161293_0 1270196.JCKI01000003_gene1810 1.72e-69 243.0 COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes,1IQDU@117747|Sphingobacteriia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents permease component mlaE - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE CMS3_k127_4161293_1 1120966.AUBU01000015_gene1816 2.371e-66 234.0 COG4221@1|root,COG4221@2|Bacteria,4NG8J@976|Bacteroidetes,47M5I@768503|Cytophagia 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS3_k127_4161293_4 1121373.KB903663_gene1008 6.664e-05 48.0 2DH09@1|root,2ZXXW@2|Bacteria,4P9BD@976|Bacteroidetes,47WSQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4161293_2 1121904.ARBP01000001_gene5704 3.286e-23 106.0 COG3064@1|root,COG3064@2|Bacteria,4NNZ9@976|Bacteroidetes,47RDR@768503|Cytophagia 976|Bacteroidetes M Membrane - - - - - - - - - - - - - CMS3_k127_4162740_1 251229.Chro_0878 1.095e-07 62.0 COG0510@1|root,COG0510@2|Bacteria 2|Bacteria M ethanolamine kinase activity strN - 2.7.1.72,2.7.1.89 ko:K04343,ko:K07251,ko:K18844 ko00730,ko01100,map00730,map01100 M00766 R02134,R02225 RC00002,RC00017,RC00078 br01600,ko00000,ko00001,ko00002,ko01000,ko01504 - - - APH,Choline_kinase CMS3_k127_4162740_0 251229.Chro_0876 5.948e-266 834.0 COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,1G2MT@1117|Cyanobacteria,3VNJZ@52604|Pleurocapsales 1117|Cyanobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_hydro_2_C,Glycos_transf_2 CMS3_k127_4165223_1 1121904.ARBP01000002_gene7111 6.865e-263 819.0 COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47MR5@768503|Cytophagia 976|Bacteroidetes E RagB SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_4165223_0 1121904.ARBP01000002_gene7112 1.184e-303 945.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JHW@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4167601_3 362418.IW19_05930 2.278e-56 202.0 COG0558@1|root,COG0558@2|Bacteria,4NM6N@976|Bacteroidetes,1I1CT@117743|Flavobacteriia 976|Bacteroidetes I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf CMS3_k127_4167601_1 1121904.ARBP01000011_gene1505 1.331e-72 272.0 COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,47M8I@768503|Cytophagia 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - - CMS3_k127_4167601_2 1356852.N008_06865 1.322e-58 218.0 28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,47NIB@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_4167601_0 926549.KI421517_gene1437 7.697e-273 867.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47K68@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4167601_4 761193.Runsl_1909 1.38e-18 94.0 2E4RS@1|root,32ZKA@2|Bacteria,4NVN5@976|Bacteroidetes,47RDU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4168756_0 1122176.KB903549_gene1226 7.074e-140 467.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_4168756_1 1237149.C900_05897 1.664e-23 116.0 COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47Y2E@768503|Cytophagia 976|Bacteroidetes T Two component regulator three Y domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_4192882_0 1121904.ARBP01000001_gene5848 6.642e-183 588.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47U0V@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - Laminin_G_3,PSCyt1,PSCyt2,PSD1 CMS3_k127_4192882_1 1353529.M899_0392 4.786e-32 139.0 COG1470@1|root,COG1470@2|Bacteria,1QX8S@1224|Proteobacteria,431GQ@68525|delta/epsilon subdivisions,2WW7Q@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - - - - - - - - - - ASH,TMEM131_like CMS3_k127_421541_3 5722.XP_001326750.1 2.688e-26 125.0 COG0666@1|root,KOG4177@2759|Eukaryota 5722.XP_001326750.1|- I spectrin binding - - - - - - - - - - - - - CMS3_k127_421541_0 1121957.ATVL01000008_gene4316 6.605e-118 406.0 COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,47KA3@768503|Cytophagia 976|Bacteroidetes L Helix-hairpin-helix motif - - - - - - - - - - - - HHH_3 CMS3_k127_421541_2 313606.M23134_00454 1.27e-37 152.0 COG1555@1|root,COG1555@2|Bacteria,4NQC1@976|Bacteroidetes,47Q92@768503|Cytophagia 976|Bacteroidetes L photosystem II stabilization - - - - - - - - - - - - - CMS3_k127_421541_1 866536.Belba_3019 2.578e-64 224.0 COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,47K0F@768503|Cytophagia 976|Bacteroidetes H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M CMS3_k127_4223323_0 926549.KI421517_gene3478 3.385e-148 474.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,47JZ7@768503|Cytophagia 976|Bacteroidetes K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS3_k127_4223323_1 641526.ADIWIN_3513 1.817e-124 414.0 COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1HX9D@117743|Flavobacteriia 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - CBM_6,GSDH CMS3_k127_4223323_3 1279009.ADICEAN_00946 4.59e-37 149.0 COG1360@1|root,COG1360@2|Bacteria,4NGHP@976|Bacteroidetes,47NTZ@768503|Cytophagia 976|Bacteroidetes N OmpA family - - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA CMS3_k127_4223323_2 926562.Oweho_3538 5.005e-79 267.0 COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia,2PAMI@246874|Cryomorphaceae 976|Bacteroidetes J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C CMS3_k127_4232557_1 679200.HMPREF9333_01919 6.88e-92 316.0 COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia 186801|Clostridia C Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM CMS3_k127_4232557_2 1313421.JHBV01000029_gene2018 1.631e-56 214.0 COG2124@1|root,COG2124@2|Bacteria,4NG9Z@976|Bacteroidetes,1IVH3@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome P450 - - - - - - - - - - - - p450 CMS3_k127_4232557_3 485918.Cpin_5677 2.661e-51 195.0 COG3239@1|root,COG3239@2|Bacteria 2|Bacteria I unsaturated fatty acid biosynthetic process - - 1.14.19.3 ko:K00508 ko00591,ko01100,map00591,map01100 - R07063 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS3_k127_4232557_0 1107311.Q767_10525 1.051e-155 494.0 COG1032@1|root,COG1032@2|Bacteria,4NFPW@976|Bacteroidetes,1INE4@117743|Flavobacteriia,2NZ97@237|Flavobacterium 976|Bacteroidetes C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS3_k127_423692_2 1122176.KB903560_gene3560 8.963e-41 156.0 COG1595@1|root,COG1595@2|Bacteria,4NN4K@976|Bacteroidetes,1IT6N@117747|Sphingobacteriia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily fecI - - - - - - - - - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_423692_3 1122179.KB890413_gene4911 1.705e-33 134.0 COG0071@1|root,COG0071@2|Bacteria,4NW0V@976|Bacteroidetes,1IZSR@117747|Sphingobacteriia 976|Bacteroidetes O Hsp20/alpha crystallin family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS3_k127_423692_1 641524.ADICYQ_1387 4.883e-84 284.0 2DBMF@1|root,2Z9YG@2|Bacteria,4NPWU@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_423692_0 1121904.ARBP01000027_gene713 2.449e-172 573.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes 976|Bacteroidetes V permease - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_423692_4 1123277.KB893201_gene6423 2.078e-25 108.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QZJ@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_423692_5 880071.Fleli_0364 1.29e-07 65.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - OmpA,YadA_anchor,YadA_head,YadA_stalk CMS3_k127_4239359_0 1250278.JQNQ01000001_gene1265 1.283e-93 323.0 COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1HWWU@117743|Flavobacteriia 976|Bacteroidetes O Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH CMS3_k127_4239387_1 760192.Halhy_1889 2.59e-40 159.0 COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1IS1E@117747|Sphingobacteriia 976|Bacteroidetes G polysaccharide deacetylase - - - - - - - - - - - - - CMS3_k127_4239387_2 999419.HMPREF1077_03657 3.937e-32 138.0 COG2348@1|root,COG2348@2|Bacteria,4NQ1R@976|Bacteroidetes,2FTKE@200643|Bacteroidia,22Y8E@171551|Porphyromonadaceae 976|Bacteroidetes V Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 CMS3_k127_4239387_0 435591.BDI_1151 3.088e-63 224.0 COG0035@1|root,COG0035@2|Bacteria,4NFZM@976|Bacteroidetes,2FN3M@200643|Bacteroidia,22WRM@171551|Porphyromonadaceae 976|Bacteroidetes F uracil phosphoribosyltransferase upp - 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase CMS3_k127_4239387_3 880071.Fleli_2051 1.464e-13 77.0 2E5FG@1|root,33075@2|Bacteria,4NWB7@976|Bacteroidetes,47QE3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4241258_1 1288963.ADIS_0984 7.494e-05 46.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,47MF2@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_4241258_0 984262.SGRA_2365 2.799e-253 817.0 COG1470@1|root,COG4935@1|root,COG1470@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1IWE5@117747|Sphingobacteriia 976|Bacteroidetes O Proprotein convertase P-domain - - - - - - - - - - - - P_proprotein,Reprolysin_4 CMS3_k127_4248157_4 1121101.HMPREF1532_03781 1.209e-25 113.0 COG1561@1|root,COG1561@2|Bacteria,4NEU4@976|Bacteroidetes,2FPBF@200643|Bacteroidia,4AKRI@815|Bacteroidaceae 976|Bacteroidetes S stress-induced protein - - - - - - - - - - - - DUF1732,YicC_N CMS3_k127_4248157_5 1304866.K413DRAFT_4933 2.619e-18 93.0 COG1234@1|root,COG1234@2|Bacteria,1V1J7@1239|Firmicutes,24F18@186801|Clostridia,36G02@31979|Clostridiaceae 186801|Clostridia S beta-lactamase superfamily III - - - - - - - - - - - - Lactamase_B,Lactamase_B_2,UPF0227 CMS3_k127_4248157_3 313606.M23134_04687 2.304e-64 230.0 COG0584@1|root,COG0584@2|Bacteria,4NGNU@976|Bacteroidetes,47Q6P@768503|Cytophagia 976|Bacteroidetes C Glycerophosphoryl diester phosphodiesterase family - - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD CMS3_k127_4248157_2 1122176.KB903554_gene3882 1.439e-87 297.0 COG2107@1|root,COG2107@2|Bacteria,4NFAN@976|Bacteroidetes,1INXU@117747|Sphingobacteriia 976|Bacteroidetes S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnD - - ko:K11785 ko00130,ko01110,map00130,map01110 - R08589 RC02330 ko00000,ko00001,ko01000 - - - VitK2_biosynth CMS3_k127_4248157_0 1121904.ARBP01000005_gene4788 2.854e-121 403.0 COG3214@1|root,COG3214@2|Bacteria,4NF6V@976|Bacteroidetes,47TAH@768503|Cytophagia 976|Bacteroidetes S Winged helix DNA-binding domain - - - ko:K09927 - - - - ko00000 - - - HTH_42 CMS3_k127_4248157_6 1356852.N008_17390 1.45e-11 75.0 28IM1@1|root,2Z8MK@2|Bacteria,4NIZ0@976|Bacteroidetes,47SFS@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4248157_1 485918.Cpin_6261 9.061e-101 335.0 COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia 976|Bacteroidetes H PFAM Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_23 CMS3_k127_4256496_4 1408473.JHXO01000008_gene2781 1.579e-59 215.0 COG1195@1|root,COG1195@2|Bacteria,4NFHN@976|Bacteroidetes,2FMHP@200643|Bacteroidia 976|Bacteroidetes L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_15,SMC_N CMS3_k127_4256496_0 929556.Solca_4218 4.165e-138 446.0 COG1071@1|root,COG1071@2|Bacteria,4NF2J@976|Bacteroidetes,1IPU9@117747|Sphingobacteriia 976|Bacteroidetes C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh CMS3_k127_4256496_5 631362.Thi970DRAFT_01597 3.245e-55 197.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1WWQB@135613|Chromatiales 135613|Chromatiales H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB CMS3_k127_4256496_2 1189620.AJXL01000003_gene1927 8.368e-70 244.0 COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,1HY5E@117743|Flavobacteriia,2NU12@237|Flavobacterium 976|Bacteroidetes S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 CMS3_k127_4256496_3 984262.SGRA_0890 5.59e-60 228.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - CHU_C,PKD,SprB CMS3_k127_4256496_6 929556.Solca_4234 2.282e-47 179.0 COG1714@1|root,COG1714@2|Bacteria,4NH7U@976|Bacteroidetes,1IRZA@117747|Sphingobacteriia 976|Bacteroidetes S pfam rdd - - - - - - - - - - - - RDD CMS3_k127_4256496_1 1519464.HY22_14160 4.981e-98 333.0 COG1300@1|root,COG1300@2|Bacteria 2|Bacteria CP Membrane - - - ko:K06384 - - - - ko00000 - - - SpoIIM CMS3_k127_4258282_0 984262.SGRA_4042 0.0 1209.0 COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia 976|Bacteroidetes S Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,PKD,Peptidase_M36 CMS3_k127_4258282_5 1035193.HMPREF9073_02013 1.147e-05 57.0 COG3212@1|root,COG3212@2|Bacteria,4NTGN@976|Bacteroidetes,1II7H@117743|Flavobacteriia,1ETEX@1016|Capnocytophaga 976|Bacteroidetes S Putative beta-lactamase-inhibitor-like, PepSY-like - - - - - - - - - - - - PepSY_like CMS3_k127_4258282_3 1122179.KB890491_gene4476 6.188e-07 53.0 COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,1IR93@117747|Sphingobacteriia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - CMS3_k127_4258282_1 1122176.KB903549_gene1226 8.409e-153 517.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_4258282_4 326427.Cagg_0898 3.8e-06 56.0 COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,377BU@32061|Chloroflexia 32061|Chloroflexia K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_4258282_2 246197.MXAN_5997 1.627e-48 179.0 COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,439QP@68525|delta/epsilon subdivisions,2X537@28221|Deltaproteobacteria,2Z01T@29|Myxococcales 28221|Deltaproteobacteria L Helix-hairpin-helix domain dpbF - - - - - - - - - - - HHH_5,HHH_8 CMS3_k127_4270405_1 1279009.ADICEAN_01481 7.752e-42 160.0 28M3Z@1|root,32ZEY@2|Bacteria,4NUZS@976|Bacteroidetes,47SGM@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4270405_2 926549.KI421517_gene2010 2.068e-17 94.0 2DTRJ@1|root,33MDI@2|Bacteria,4NVIB@976|Bacteroidetes,47RU9@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4270405_3 1121381.JNIV01000014_gene4345 0.0001963 51.0 2EHDW@1|root,33B5R@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4270405_0 929556.Solca_2597 1.263e-122 406.0 COG0506@1|root,COG0506@2|Bacteria,4NEH5@976|Bacteroidetes,1IQ4H@117747|Sphingobacteriia 976|Bacteroidetes E Proline dehydrogenase putA - - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh CMS3_k127_4271923_3 1237149.C900_00335 2.735e-107 369.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz CMS3_k127_4271923_2 1338011.BD94_3292 1.847e-147 473.0 COG1089@1|root,COG1089@2|Bacteria,4NEB6@976|Bacteroidetes,1HY1Q@117743|Flavobacteriia,34S1A@308865|Elizabethkingia 976|Bacteroidetes M GDP-mannose 4,6 dehydratase gmd - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd CMS3_k127_4271923_1 153721.MYP_1000 6.508e-151 482.0 COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia 976|Bacteroidetes GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase CMS3_k127_4271923_0 1209072.ALBT01000032_gene2172 1.637e-157 516.0 COG5297@1|root,COG5297@2|Bacteria,1NDMY@1224|Proteobacteria,1RN6M@1236|Gammaproteobacteria,1FIJ0@10|Cellvibrio 1236|Gammaproteobacteria G Glycosyl hydrolase family 9 - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_4_9,CelD_N,Glyco_hydro_9 CMS3_k127_4275245_2 880070.Cycma_4098 6.723e-26 109.0 COG1409@1|root,COG1409@2|Bacteria,4NI6R@976|Bacteroidetes,47U94@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos,Metallophos_2 CMS3_k127_4275245_1 1408433.JHXV01000025_gene4022 4.887e-101 336.0 28N6F@1|root,30YAD@2|Bacteria,4PBVE@976|Bacteroidetes,1ICP8@117743|Flavobacteriia,2PBGQ@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4275245_0 1120968.AUBX01000017_gene1932 3.995e-141 456.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JR2@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4281274_1 1454007.JAUG01000024_gene842 3.191e-60 215.0 COG0009@1|root,COG0009@2|Bacteria,4NDZR@976|Bacteroidetes,1IQWM@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the SUA5 family yciO - - - - - - - - - - - Sua5_yciO_yrdC CMS3_k127_4281274_2 1121859.KB890740_gene3893 9.924e-56 201.0 COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,47N8D@768503|Cytophagia 976|Bacteroidetes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N CMS3_k127_4281274_0 926562.Oweho_1913 1.378e-200 656.0 COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1HXVQ@117743|Flavobacteriia,2PA61@246874|Cryomorphaceae 976|Bacteroidetes S Motility related/secretion protein sprA - - - - - - - - - - - SprA_N CMS3_k127_4283418_1 530564.Psta_0688 2.07e-146 473.0 28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - CMS3_k127_4283418_0 688270.Celal_4275 1.946e-163 524.0 COG0025@1|root,COG0025@2|Bacteria,4NF54@976|Bacteroidetes,1HYT6@117743|Flavobacteriia,1FA6T@104264|Cellulophaga 976|Bacteroidetes P Sodium/hydrogen exchanger family - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger CMS3_k127_4283418_2 1123248.KB893318_gene4097 5.943e-131 427.0 COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes,1IR28@117747|Sphingobacteriia 976|Bacteroidetes M Mycolic acid cyclopropane synthetase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS CMS3_k127_4283418_3 643867.Ftrac_1001 4.002e-08 66.0 COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia 976|Bacteroidetes S COGs COG1033 exporter of the RND superfamily protein - - - ko:K07003 - - - - ko00000 - - - MMPL CMS3_k127_428855_0 1313421.JHBV01000030_gene2269 7.463e-73 265.0 COG4783@1|root,COG4783@2|Bacteria,4NM0X@976|Bacteroidetes 976|Bacteroidetes S PFAM Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 CMS3_k127_428855_1 1111730.ATTM01000004_gene1956 2.141e-31 128.0 COG4096@1|root,COG4096@2|Bacteria,4NNKI@976|Bacteroidetes,1I22N@117743|Flavobacteriia,2NVYQ@237|Flavobacterium 976|Bacteroidetes V Restriction endonuclease subunit R - - - - - - - - - - - - HSDR_N_2 CMS3_k127_428855_2 1168034.FH5T_00520 5.05e-19 87.0 COG0419@1|root,COG0419@2|Bacteria,4NH9H@976|Bacteroidetes,2FPAQ@200643|Bacteroidia 976|Bacteroidetes L COG0419 ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,SbcCD_C CMS3_k127_4298557_0 1121373.KB903625_gene3160 9.373e-186 608.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop CMS3_k127_4298557_1 1408433.JHXV01000015_gene1777 7.438e-88 296.0 COG3279@1|root,COG3279@2|Bacteria,4NNHE@976|Bacteroidetes,1HZAH@117743|Flavobacteriia,2PATW@246874|Cryomorphaceae 976|Bacteroidetes K Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_4304155_4 1279009.ADICEAN_02861 7.767e-23 100.0 COG0750@1|root,COG0750@2|Bacteria,4NEAR@976|Bacteroidetes,47JDH@768503|Cytophagia 976|Bacteroidetes M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50 CMS3_k127_4304155_1 1123057.P872_02220 2.039e-141 457.0 COG0082@1|root,COG0082@2|Bacteria,4NDXJ@976|Bacteroidetes,47KB2@768503|Cytophagia 976|Bacteroidetes E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt CMS3_k127_4304155_0 1121918.ARWE01000001_gene883 7.094e-157 507.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,42MQU@68525|delta/epsilon subdivisions,2WK6F@28221|Deltaproteobacteria 28221|Deltaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM CMS3_k127_4304155_2 1122176.KB903538_gene1459 5.066e-36 143.0 COG4665@1|root,COG4665@2|Bacteria,4NTWB@976|Bacteroidetes 976|Bacteroidetes Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS3_k127_4304155_3 1121481.AUAS01000004_gene1251 5.544e-30 138.0 COG0631@1|root,COG0631@2|Bacteria,4NPJV@976|Bacteroidetes,47Q45@768503|Cytophagia 976|Bacteroidetes T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 CMS3_k127_4306905_2 1123278.KB893499_gene323 1.805e-100 336.0 COG1940@1|root,COG1940@2|Bacteria,4NH8S@976|Bacteroidetes,47J9G@768503|Cytophagia 976|Bacteroidetes GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK CMS3_k127_4306905_1 1121904.ARBP01000026_gene692 2.911e-112 367.0 COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes,47KN3@768503|Cytophagia 976|Bacteroidetes IQ Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 CMS3_k127_4306905_0 616991.JPOO01000003_gene1587 1.203e-316 994.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHPU@976|Bacteroidetes,1IIX3@117743|Flavobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C,HEAT_2 CMS3_k127_4306905_3 1121904.ARBP01000001_gene5603 6.375e-51 182.0 COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,47KZS@768503|Cytophagia 976|Bacteroidetes S PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_4309463_2 1122176.KB903535_gene1996 1.098e-20 93.0 COG0639@1|root,COG0639@2|Bacteria,4NEQW@976|Bacteroidetes,1IYTE@117747|Sphingobacteriia 976|Bacteroidetes T Calcineurin-like phosphoesterase - - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos CMS3_k127_4309463_1 1189612.A33Q_3345 4.492e-54 201.0 COG2319@1|root,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,47JUN@768503|Cytophagia 976|Bacteroidetes S PFAM WD domain, G-beta repeat - - - - - - - - - - - - WD40 CMS3_k127_4309463_3 153721.MYP_28 1.298e-19 96.0 COG3599@1|root,COG3599@2|Bacteria,4NQDF@976|Bacteroidetes,47QRC@768503|Cytophagia 976|Bacteroidetes D TIGRFAM DivIVA domain divIVA - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA CMS3_k127_4309463_0 743722.Sph21_0679 9.102e-84 280.0 COG0717@1|root,COG0717@2|Bacteria,4P12W@976|Bacteroidetes,1IX12@117747|Sphingobacteriia 976|Bacteroidetes F Belongs to the dCTP deaminase family - - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - - CMS3_k127_4313357_3 1049564.TevJSym_aq00680 3.701e-81 274.0 COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria U Part of a membrane complex involved in electron transport rnfE2 - - ko:K03613 - - - - ko00000 - - - Rnf-Nqr CMS3_k127_4313357_2 1049564.TevJSym_aq00670 4.876e-82 276.0 COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Part of a membrane complex involved in electron transport rnfA - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr CMS3_k127_4313357_1 1121887.AUDK01000023_gene3473 2.123e-87 300.0 COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1HXDG@117743|Flavobacteriia,2NW6Q@237|Flavobacterium 976|Bacteroidetes H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE CMS3_k127_4313357_4 290397.Adeh_3871 2.558e-20 96.0 2DP5T@1|root,330N5@2|Bacteria,1Q5DS@1224|Proteobacteria,43134@68525|delta/epsilon subdivisions,2WX04@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF4395) - - - - - - - - - - - - DUF4395 CMS3_k127_4313357_0 1250232.JQNJ01000001_gene1549 5.385e-132 448.0 COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HTH_18,HisKA,Response_reg,TPR_12,TPR_8 CMS3_k127_4315861_2 143224.JQMD01000002_gene1235 1.623e-10 62.0 COG3540@1|root,COG3540@2|Bacteria,4PDR1@976|Bacteroidetes,1I0ZY@117743|Flavobacteriia 2|Bacteria P PhoD-like phosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N CMS3_k127_4315861_1 243233.MCA0770 2.106e-270 841.0 COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1XE4Y@135618|Methylococcales 1236|Gammaproteobacteria C Glutamate synthase, NADH NADPH, small subunit - - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - DHODB_Fe-S_bind,Fer4,Fer4_20,NAD_binding_1,Pyr_redox_2 CMS3_k127_4315861_0 1049564.TevJSym_al00210 0.0 1126.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1J7JF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin nifJ - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C CMS3_k127_4319767_0 1237149.C900_03476 5.618e-149 484.0 COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region mdlA - - ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran CMS3_k127_4319767_2 926549.KI421517_gene1621 6.682e-37 142.0 COG0316@1|root,COG0316@2|Bacteria,4NS6K@976|Bacteroidetes,47R1C@768503|Cytophagia 976|Bacteroidetes S Belongs to the HesB IscA family iscA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn CMS3_k127_4319767_1 1124780.ANNU01000008_gene2643 5.862e-64 239.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,47JP5@768503|Cytophagia 976|Bacteroidetes I Methylmalonyl-CoA mutase N-terminal domain subunit mutA - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase CMS3_k127_4320120_1 1122621.ATZA01000009_gene258 5.086e-33 131.0 COG0618@1|root,COG0618@2|Bacteria,4NEXE@976|Bacteroidetes,1IPG0@117747|Sphingobacteriia 976|Bacteroidetes S phosphoesterase RecJ domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS3_k127_4320120_2 1122179.KB890415_gene2013 1.465e-10 71.0 28MPU@1|root,2ZAYW@2|Bacteria,4NXA9@976|Bacteroidetes,1IYAK@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4320120_0 1305737.JAFX01000001_gene3210 4.722e-124 404.0 COG0320@1|root,COG0320@2|Bacteria,4NEB5@976|Bacteroidetes,47JGZ@768503|Cytophagia 976|Bacteroidetes H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM CMS3_k127_4345469_0 1122927.KB895414_gene5140 1.329e-177 570.0 COG3669@1|root,COG3669@2|Bacteria,1TSG7@1239|Firmicutes,4HEKS@91061|Bacilli,26UH5@186822|Paenibacillaceae 91061|Bacilli G alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,F5_F8_type_C CMS3_k127_4345573_3 616991.JPOO01000001_gene3855 5.049e-83 285.0 COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4PNA4@976|Bacteroidetes,1IK7X@117743|Flavobacteriia,23G96@178469|Arenibacter 976|Bacteroidetes CG PKD domain - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,GSDH,PKD,ThuA CMS3_k127_4345573_1 760192.Halhy_1535 1.809e-192 610.0 COG0673@1|root,COG0673@2|Bacteria,4NG5T@976|Bacteroidetes,1IRR9@117747|Sphingobacteriia 976|Bacteroidetes S COGs COG0673 dehydrogenase and related protein - - - - - - - - - - - - GFO_IDH_MocA,Oxidoreduct_C CMS3_k127_4345573_0 344747.PM8797T_30207 4.8e-202 641.0 COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes 203682|Planctomycetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_4345573_2 344747.PM8797T_20578 1.648e-107 363.0 COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - 3.1.6.4 ko:K01132 ko00531,ko01100,ko04142,map00531,map01100,map04142 M00077,M00079 R07806 - ko00000,ko00001,ko00002,ko01000 - - - Sulfatase CMS3_k127_4345650_5 761193.Runsl_4275 1.131e-40 152.0 COG3328@1|root,COG3328@2|Bacteria,4NFQS@976|Bacteroidetes,47NSF@768503|Cytophagia 976|Bacteroidetes L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut CMS3_k127_4345650_0 760142.Hipma_0965 5.539e-82 279.0 COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2X6AV@28221|Deltaproteobacteria 28221|Deltaproteobacteria L SPTR IstB domain protein ATP-binding protein - - - - - - - - - - - - IstB_IS21 CMS3_k127_4345650_2 760192.Halhy_2259 3.047e-63 227.0 COG4584@1|root,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,1IPYU@117747|Sphingobacteriia 976|Bacteroidetes L PFAM Integrase, catalytic core - - - - - - - - - - - - rve CMS3_k127_4345650_3 760142.Hipma_0392 6.018e-56 205.0 COG4584@1|root,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,42P15@68525|delta/epsilon subdivisions,2WK8D@28221|Deltaproteobacteria,2M7JB@213113|Desulfurellales 28221|Deltaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_7,rve CMS3_k127_4345650_4 1173024.KI912153_gene171 1.345e-48 181.0 COG3464@1|root,COG3464@2|Bacteria,1G1W2@1117|Cyanobacteria 1117|Cyanobacteria L PFAM Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,zf-ISL3 CMS3_k127_4345650_6 1041159.AZUW01000008_gene4443 1.21e-21 98.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,SAM_1 CMS3_k127_4345650_1 760192.Halhy_1854 8.441e-67 231.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_4347540_1 746697.Aeqsu_2178 1.111e-67 233.0 COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1HXM8@117743|Flavobacteriia 976|Bacteroidetes C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS3_k127_4347540_2 448385.sce1514 9.268e-56 200.0 COG0431@1|root,COG0431@2|Bacteria,1MXQ8@1224|Proteobacteria,43B5X@68525|delta/epsilon subdivisions,2X6JH@28221|Deltaproteobacteria,2Z3BE@29|Myxococcales 28221|Deltaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red CMS3_k127_4347540_3 743722.Sph21_0328 6.474e-16 81.0 COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,1IU87@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 CMS3_k127_4347540_4 929562.Emtol_2950 5.754e-12 71.0 COG0594@1|root,COG0594@2|Bacteria,4NUMM@976|Bacteroidetes,47S3A@768503|Cytophagia 976|Bacteroidetes J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P CMS3_k127_4347540_0 929556.Solca_2578 4.741e-166 538.0 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 CMS3_k127_4353135_0 1121904.ARBP01000018_gene2599 7.743e-248 783.0 COG0495@1|root,COG0495@2|Bacteria,4NE5K@976|Bacteroidetes,47MI0@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,DUF559,tRNA-synt_1,tRNA-synt_1_2 CMS3_k127_4353135_1 1121904.ARBP01000002_gene6992 2.515e-71 250.0 28JI1@1|root,2Z9BG@2|Bacteria,4NMDW@976|Bacteroidetes,47Q2P@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4353135_2 760192.Halhy_2760 5.251e-23 100.0 COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1INZ0@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Bacterial transferase hexapeptide (three repeats) - - 2.3.1.201 ko:K13018 ko00520,map00520 - R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 - - - Hexapep,Hexapep_2 CMS3_k127_4365812_0 313603.FB2170_14833 0.0 1249.0 COG0755@1|root,COG0755@2|Bacteria,4NDY1@976|Bacteroidetes,1HXDN@117743|Flavobacteriia,2PG6S@252356|Maribacter 976|Bacteroidetes O Cytochrome C assembly protein ccmC - - - - - - - - - - - Cytochrom_C_asm,ResB CMS3_k127_4365812_2 313603.FB2170_14828 6.905e-80 274.0 28PU4@1|root,2ZCF6@2|Bacteria,4NTXA@976|Bacteroidetes,1I497@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4365812_1 313603.FB2170_14823 2.566e-102 338.0 2919D@1|root,2ZNWG@2|Bacteria,4NMU5@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4366151_3 4641.GSMUA_Achr3P00900_001 2.203e-08 57.0 COG0814@1|root,KOG1305@2759|Eukaryota,37M9V@33090|Viridiplantae,3GG2B@35493|Streptophyta,3KMG0@4447|Liliopsida 35493|Streptophyta E Transmembrane amino acid transporter protein - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0005789,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0012505,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0031090,GO:0031984,GO:0034220,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0098588,GO:0098656,GO:0098805,GO:0098827,GO:1903825,GO:1905039 - ko:K14992,ko:K14993 ko04727,map04727 - - - ko00000,ko00001,ko02000 2.A.18.6,2.A.18.6.8 - - Aa_trans CMS3_k127_4366151_2 1392488.JHZY01000004_gene1651 3.176e-20 94.0 2DTS4@1|root,33MFD@2|Bacteria,4NZQB@976|Bacteroidetes,1IB16@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4366151_0 1168034.FH5T_13080 6.53e-61 221.0 2C23X@1|root,31B63@2|Bacteria,4NS2W@976|Bacteroidetes,2FT67@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4366151_1 880071.Fleli_1391 3.307e-52 193.0 COG4886@1|root,COG4886@2|Bacteria,4NHJ3@976|Bacteroidetes,47NN3@768503|Cytophagia 976|Bacteroidetes S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - LRR_4 CMS3_k127_4372452_4 1313421.JHBV01000029_gene1950 1.072e-44 186.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - CHU_C,PKD,SprB CMS3_k127_4372452_8 755732.Fluta_2067 6.183e-15 89.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - 3.4.21.50 ko:K01337 - - - - ko00000,ko01000,ko01002 - - - CHU_C,PKD,SprB CMS3_k127_4372452_6 926562.Oweho_1060 3.209e-37 149.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,1IJP8@117743|Flavobacteriia,2PB5D@246874|Cryomorphaceae 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_12,TPR_16,TPR_21,TPR_6,TPR_7,TPR_8 CMS3_k127_4372452_3 509635.N824_07685 1.946e-54 196.0 COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,1IUZM@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase CMS3_k127_4372452_0 1121904.ARBP01000007_gene2979 7.87e-274 866.0 COG2866@1|root,COG2866@2|Bacteria,4NEJA@976|Bacteroidetes,47KZ0@768503|Cytophagia 976|Bacteroidetes E PFAM Zinc carboxypeptidase - - - - - - - - - - - - Peptidase_M14 CMS3_k127_4372452_7 411476.BACOVA_01562 9.021e-24 104.0 2DBNW@1|root,32TXT@2|Bacteria,4NSRU@976|Bacteroidetes,2FTVT@200643|Bacteroidia,4ARWP@815|Bacteroidaceae 976|Bacteroidetes S Motility quorum-sensing regulator, toxin of MqsA - - - - - - - - - - - - MqsR_toxin CMS3_k127_4372452_2 324925.Ppha_0057 6.974e-70 249.0 COG2944@1|root,COG2944@2|Bacteria 2|Bacteria K sequence-specific DNA binding ps301 - - - - - - - - - - - DUF4065,HTH_3,MqsA_antitoxin CMS3_k127_4372452_1 518766.Rmar_1248 6.492e-163 529.0 COG1008@1|root,COG1008@2|Bacteria,4NEJ1@976|Bacteroidetes,1FINN@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Proton-conducting membrane transporter - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M CMS3_k127_4372452_5 1349785.BAUG01000002_gene23 1.524e-41 162.0 COG0860@1|root,COG0860@2|Bacteria,4P3RX@976|Bacteroidetes 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_3 CMS3_k127_4377484_4 1178825.ALIH01000004_gene2795 1.363e-121 400.0 COG0673@1|root,COG0673@2|Bacteria,4NJEP@976|Bacteroidetes,1I3KI@117743|Flavobacteriia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_4377484_1 143224.JQMD01000002_gene3082 2.738e-180 573.0 COG2271@1|root,COG2271@2|Bacteria,4NGCR@976|Bacteroidetes,1HWZ4@117743|Flavobacteriia 976|Bacteroidetes G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_4377484_6 1121904.ARBP01000004_gene783 7.075e-72 248.0 COG1878@1|root,COG1878@2|Bacteria,4NFYB@976|Bacteroidetes,47XKZ@768503|Cytophagia 976|Bacteroidetes S Putative cyclase - - - - - - - - - - - - Cyclase CMS3_k127_4377484_2 1121904.ARBP01000004_gene784 6.576e-168 533.0 COG0473@1|root,COG0473@2|Bacteria,4NEBE@976|Bacteroidetes,47MDN@768503|Cytophagia 976|Bacteroidetes CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS3_k127_4377484_0 886379.AEWI01000039_gene2839 3.991e-316 982.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,2FQDG@200643|Bacteroidia,3XJTH@558415|Marinilabiliaceae 976|Bacteroidetes G Fibronectin type III-like domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_4377484_5 1121912.AUHD01000004_gene1972 1.547e-104 350.0 COG1804@1|root,COG1804@2|Bacteria,4NEA8@976|Bacteroidetes,1I0MK@117743|Flavobacteriia 976|Bacteroidetes C Pfam CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 CMS3_k127_4377484_3 1122176.KB903587_gene4432 7.892e-153 489.0 COG0604@1|root,COG0604@2|Bacteria,4NGIY@976|Bacteroidetes,1IXQ0@117747|Sphingobacteriia 976|Bacteroidetes C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS3_k127_437872_2 1124780.ANNU01000063_gene607 5.656e-91 303.0 COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,47N5W@768503|Cytophagia 976|Bacteroidetes M sugar transferase wcaJ_2 - 2.7.8.6 ko:K00996,ko:K03606 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 CMS3_k127_437872_1 32057.KB217478_gene6787 1.69e-91 307.0 COG1922@1|root,COG1922@2|Bacteria,1G0ID@1117|Cyanobacteria,1HQS8@1161|Nostocales 1117|Cyanobacteria M Glycosyl transferase WecB/TagA/CpsF family - - - - - - - - - - - - Glyco_tran_WecB CMS3_k127_437872_0 1123373.ATXI01000008_gene1560 1.034e-152 488.0 COG2605@1|root,COG2605@2|Bacteria,2GIF3@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria S GHMP kinases C terminal - - 2.7.1.168 ko:K07031 ko00540,map00540 - R09770 RC00002,RC00078 ko00000,ko00001,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CMS3_k127_437872_3 761193.Runsl_4187 2.148e-73 252.0 COG0279@1|root,COG0279@2|Bacteria,4NJX7@976|Bacteroidetes,47KZ6@768503|Cytophagia 976|Bacteroidetes G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 CMS3_k127_437872_4 1408473.JHXO01000011_gene3056 2.324e-72 250.0 COG1208@1|root,COG1208@2|Bacteria,4NFDB@976|Bacteroidetes,2FSCA@200643|Bacteroidia 976|Bacteroidetes JM Nucleotidyl transferase gmhB - 2.7.7.71 ko:K15669 ko00540,map00540 - R09772 RC00002 ko00000,ko00001,ko01000 - - - CBS,NTP_transferase CMS3_k127_437872_6 760192.Halhy_0365 1.595e-48 180.0 COG0241@1|root,COG0241@2|Bacteria,4NR54@976|Bacteroidetes,1IU3D@117747|Sphingobacteriia 976|Bacteroidetes E D,D-heptose 1,7-bisphosphate phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hydrolase_like,PNK3P CMS3_k127_437872_5 163908.KB235896_gene4040 1.506e-71 249.0 COG1216@1|root,COG1216@2|Bacteria,1G10I@1117|Cyanobacteria,1HS3Z@1161|Nostocales 1117|Cyanobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_4406548_2 313595.P700755_001336 3.365e-20 95.0 COG0697@1|root,COG0697@2|Bacteria,4NEHX@976|Bacteroidetes,1HYA2@117743|Flavobacteriia,4C39N@83612|Psychroflexus 976|Bacteroidetes EG EamA-like transporter family fjo11 - - - - - - - - - - - EamA CMS3_k127_4406548_3 1227352.C173_07382 2.607e-15 86.0 COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,4HVNC@91061|Bacilli,26WDS@186822|Paenibacillaceae 91061|Bacilli O DnaJ C terminal domain - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C CMS3_k127_4406548_4 1469607.KK073768_gene2261 5.032e-15 83.0 COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria,1HP5J@1161|Nostocales 1117|Cyanobacteria J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 CMS3_k127_4406548_1 296591.Bpro_5441 4.694e-25 113.0 COG0500@1|root,COG2226@2|Bacteria,1N1HA@1224|Proteobacteria 1224|Proteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 CMS3_k127_4406548_0 742766.HMPREF9455_01257 1.374e-29 120.0 COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,2FNBZ@200643|Bacteroidia,22VYM@171551|Porphyromonadaceae 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_4416958_0 880073.Calab_3557 4.817e-96 321.0 COG1215@1|root,COG1215@2|Bacteria,2NQN3@2323|unclassified Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_tranf_2_4,Glycos_transf_2 CMS3_k127_4416958_3 1239962.C943_04112 1.921e-31 127.0 COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,47QQD@768503|Cytophagia 976|Bacteroidetes J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 CMS3_k127_4416958_2 487796.Flav2ADRAFT_1513 5.644e-34 132.0 COG0238@1|root,COG0238@2|Bacteria,4NSAR@976|Bacteroidetes,1I2TD@117743|Flavobacteriia 976|Bacteroidetes J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 CMS3_k127_4416958_1 762903.Pedsa_2292 4.003e-41 156.0 COG0359@1|root,COG0359@2|Bacteria,4NNRP@976|Bacteroidetes,1IRUM@117747|Sphingobacteriia 976|Bacteroidetes J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N CMS3_k127_4416958_4 504472.Slin_1732 3.776e-26 119.0 COG3743@1|root,COG3743@2|Bacteria,4NSZH@976|Bacteroidetes,47PEM@768503|Cytophagia 976|Bacteroidetes S rRNA binding - - - - - - - - - - - - HHH_5 CMS3_k127_4416958_5 1166018.FAES_4501 7.726e-23 110.0 COG2885@1|root,COG2885@2|Bacteria,4NGCV@976|Bacteroidetes,47K14@768503|Cytophagia 976|Bacteroidetes M OmpA MotB domain protein - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA CMS3_k127_4445360_2 153721.MYP_4106 3.046e-79 278.0 COG3391@1|root,COG3391@2|Bacteria,4NESV@976|Bacteroidetes,47MV5@768503|Cytophagia 976|Bacteroidetes S amine dehydrogenase activity - - - - - - - - - - - - Glu_cyclase_2 CMS3_k127_4445360_3 984262.SGRA_3592 1.505e-66 246.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K07004 - - - - ko00000 - - - Exo_endo_phos,He_PIG,LTD CMS3_k127_4445360_1 153721.MYP_4104 1.125e-102 357.0 COG4206@1|root,COG4206@2|Bacteria,4NED9@976|Bacteroidetes,47M0G@768503|Cytophagia 976|Bacteroidetes H TonB-dependent Receptor Plug btuB - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec CMS3_k127_4445360_0 1189612.A33Q_1137 7.389e-179 574.0 COG0305@1|root,COG0305@2|Bacteria,4NF8P@976|Bacteroidetes,47JB5@768503|Cytophagia 976|Bacteroidetes L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C CMS3_k127_4445360_4 1313301.AUGC01000001_gene1604 7.809e-07 59.0 COG1331@1|root,COG1331@2|Bacteria,4NMU8@976|Bacteroidetes 976|Bacteroidetes O Pfam Thioredoxin - - - - - - - - - - - - Thioredox_DsbH,Thioredoxin,Thioredoxin_7 CMS3_k127_4445812_4 671143.DAMO_0774 3.818e-19 89.0 COG2181@1|root,COG2181@2|Bacteria 2|Bacteria C nitrate reductase activity narI GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 ko:K00370,ko:K00374,ko:K02575 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00615,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.8,5.A.3.1 - iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897 Nitrate_red_gam CMS3_k127_4445812_3 616991.JPOO01000003_gene1699 3.78e-44 171.0 COG2180@1|root,COG2180@2|Bacteria 2|Bacteria C chaperone-mediated protein complex assembly narJ GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - ko:K00373,ko:K17052 ko02020,map02020 - - - ko00000,ko00001,ko02000 5.A.3.8 - iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687 Nitrate_red_del CMS3_k127_4445812_0 616991.JPOO01000003_gene1700 2.238e-261 812.0 COG1140@1|root,COG1140@2|Bacteria 2|Bacteria C nitrate reductase beta subunit narH GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189 Fer4_11,Nitr_red_bet_C CMS3_k127_4445812_2 1123234.AUKI01000022_gene2212 1.482e-94 315.0 COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,1HXS5@117743|Flavobacteriia 976|Bacteroidetes D Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - ko:K07322 - - - - ko00000 - - - DUF2249,Hemerythrin,ScdA_N CMS3_k127_4445812_1 616991.JPOO01000003_gene1701 3.483e-237 741.0 COG5013@1|root,COG5013@2|Bacteria 2|Bacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 ko:K00370,ko:K17050 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000,ko02000 5.A.3.1,5.A.3.8 - iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685 Molybdopterin,Molydop_binding,Nitr_red_alph_N CMS3_k127_44477_5 1235788.C802_00355 8.81e-32 143.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,2FM2N@200643|Bacteroidia,4AMCC@815|Bacteroidaceae 976|Bacteroidetes T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_44477_8 1120951.AUBG01000016_gene3605 1.934e-11 68.0 2E5YZ@1|root,330NH@2|Bacteria,4NV12@976|Bacteroidetes,1I59I@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_44477_6 290397.Adeh_3871 3.157e-18 92.0 2DP5T@1|root,330N5@2|Bacteria,1Q5DS@1224|Proteobacteria,43134@68525|delta/epsilon subdivisions,2WX04@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Domain of unknown function (DUF4395) - - - - - - - - - - - - DUF4395 CMS3_k127_44477_1 396588.Tgr7_1710 1.496e-89 303.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,1RNTN@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Methyltransferase - - - - - - - - - - - - Methyltransf_31 CMS3_k127_44477_2 933262.AXAM01000036_gene2177 1.859e-71 246.0 COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MMB5@213118|Desulfobacterales 28221|Deltaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC CMS3_k127_44477_9 471854.Dfer_0654 5.644e-05 45.0 COG2207@1|root,COG2207@2|Bacteria,4NPGP@976|Bacteroidetes,47RC4@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - ko:K07506 - - - - ko00000,ko03000 - - - HTH_18 CMS3_k127_44477_0 926559.JoomaDRAFT_1861 5.818e-150 491.0 COG1680@1|root,COG1680@2|Bacteria,4NKJT@976|Bacteroidetes,1I40D@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_44477_4 1408433.JHXV01000027_gene3768 4.182e-35 138.0 COG1733@1|root,COG1733@2|Bacteria,4NSVE@976|Bacteroidetes,1I4YH@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - HxlR CMS3_k127_44477_7 911045.PSE_4289 2.762e-12 72.0 COG3832@1|root,COG3832@2|Bacteria 2|Bacteria J glyoxalase III activity mxaD - - ko:K16260 ko00680,ko01120,map00680,map01120 - - - ko00000,ko00001 - - - Polyketide_cyc2 CMS3_k127_44477_3 388413.ALPR1_00935 8.015e-41 153.0 COG3070@1|root,COG3070@2|Bacteria,4NSGZ@976|Bacteroidetes 976|Bacteroidetes K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N CMS3_k127_4458253_4 1250232.JQNJ01000001_gene620 0.000131 49.0 COG0726@1|root,COG0726@2|Bacteria,4NF79@976|Bacteroidetes,1HWXT@117743|Flavobacteriia 976|Bacteroidetes G polysaccharide deacetylase - - - - - - - - - - - - - CMS3_k127_4458253_3 1519464.HY22_12190 1.109e-69 243.0 COG0767@1|root,COG0767@2|Bacteria,1FEE8@1090|Chlorobi 1090|Chlorobi Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE CMS3_k127_4458253_2 1454007.JAUG01000130_gene942 3.535e-82 300.0 COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPAI@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - CarboxypepD_reg,OmpA,PD40 CMS3_k127_4458253_0 760192.Halhy_1083 1.043e-161 517.0 COG0150@1|root,COG0150@2|Bacteria,4NE4E@976|Bacteroidetes,1IQ5E@117747|Sphingobacteriia 976|Bacteroidetes F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CMS3_k127_4458253_1 1288963.ADIS_4452 5.902e-93 314.0 COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,47JUA@768503|Cytophagia 976|Bacteroidetes I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 CMS3_k127_4458253_5 1317122.ATO12_24935 0.0001441 53.0 COG0457@1|root,COG0457@2|Bacteria,4NMWW@976|Bacteroidetes,1IA1W@117743|Flavobacteriia,2YKHM@290174|Aquimarina 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - DUF2974,NB-ARC,Sel1,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8 CMS3_k127_446525_1 1237149.C900_02654 6.262e-82 274.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 CMS3_k127_446525_2 983544.Lacal_1654 4.909e-15 83.0 29Q6S@1|root,30B5S@2|Bacteria,4NIX7@976|Bacteroidetes,1I0R1@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_446525_0 984262.SGRA_0782 3.822e-109 370.0 COG2356@1|root,COG3227@1|root,COG3291@1|root,COG2356@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,4PM49@976|Bacteroidetes 976|Bacteroidetes M PFAM Developmentally Regulated MAPK Interacting Protein - - - - - - - - - - - - Reprolysin_4 CMS3_k127_4468633_10 1168059.KB899087_gene2181 2.262e-13 76.0 COG3108@1|root,COG3108@2|Bacteria 2|Bacteria S Peptidase M15 - - 3.2.1.17 ko:K01185,ko:K02395 - - - - ko00000,ko01000,ko02035 - - - Peptidase_M15_3 CMS3_k127_4468633_8 1122225.AULQ01000002_gene646 5.284e-37 147.0 COG2197@1|root,COG2197@2|Bacteria,4NQVA@976|Bacteroidetes,1I31H@117743|Flavobacteriia 976|Bacteroidetes K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg CMS3_k127_4468633_5 1296415.JACC01000037_gene1091 1.936e-70 263.0 COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia,2YHP1@290174|Aquimarina 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3,TPR_12,TPR_8 CMS3_k127_4468633_7 1122176.KB903535_gene2022 4.103e-61 239.0 COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria 2|Bacteria G gluconolactonase activity - - - - - - - - - - - - CHU_C,PKD,SprB CMS3_k127_4468633_2 1124780.ANNU01000025_gene3334 2.82e-124 417.0 COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47MD4@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 CMS3_k127_4468633_1 1121904.ARBP01000002_gene7088 1.776e-137 457.0 COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_4468633_4 1270196.JCKI01000001_gene4033 3.745e-75 259.0 COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1IQQC@117747|Sphingobacteriia 976|Bacteroidetes P Membrane protein TerC, possibly involved in tellurium resistance - - - - - - - - - - - - TerC CMS3_k127_4468633_0 1120966.AUBU01000010_gene2916 2.117e-319 1001.0 COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,47KKH@768503|Cytophagia 976|Bacteroidetes J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD CMS3_k127_4468633_6 1239962.C943_01964 6.479e-70 248.0 COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes 976|Bacteroidetes M peptidase M23 - - - - - - - - - - - - Peptidase_M23 CMS3_k127_4468633_9 643867.Ftrac_2908 3.526e-28 117.0 COG0789@1|root,COG0789@2|Bacteria,4NSBD@976|Bacteroidetes,47QJY@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator ycgE - - - - - - - - - - - MerR_1 CMS3_k127_4468633_11 929703.KE386491_gene4005 1.946e-08 62.0 2DM4T@1|root,31QCU@2|Bacteria,4P9NM@976|Bacteroidetes,47RQN@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4468633_3 402777.KB235904_gene4066 4.779e-101 348.0 COG1075@1|root,COG4249@1|root,COG1075@2|Bacteria,COG4249@2|Bacteria,1G42B@1117|Cyanobacteria,1H7VS@1150|Oscillatoriales 1117|Cyanobacteria S Caspase domain - - - - - - - - - - - - LCAT,PGAP1,Peptidase_C14 CMS3_k127_4478123_0 1227739.Hsw_3687 8.042e-286 898.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,47JEZ@768503|Cytophagia 976|Bacteroidetes EU Peptidase S9, prolyl oligopeptidase active site domain protein - - - - - - - - - - - - DPPIV_N,PD40,Peptidase_S9 CMS3_k127_4478123_1 929556.Solca_0767 1.785e-16 82.0 COG2318@1|root,COG2318@2|Bacteria,4NUTN@976|Bacteroidetes,1IUDR@117747|Sphingobacteriia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_4507355_2 485918.Cpin_1816 6.249e-70 240.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1INUX@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 3 family bglX - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_4507355_4 216432.CA2559_09141 1.093e-41 159.0 COG0790@1|root,COG0790@2|Bacteria,4PKKJ@976|Bacteroidetes,1IJBX@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_4507355_1 906888.JCM19314_1585 2.402e-179 572.0 COG0277@1|root,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,1HXIK@117743|Flavobacteriia,3HJBA@363408|Nonlabens 976|Bacteroidetes C FAD linked oxidases, C-terminal domain glcD - 1.1.2.4,1.1.3.15 ko:K00102,ko:K00104 ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130 - R00197,R00475 RC00042,RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 CMS3_k127_4507355_3 1500893.JQNB01000001_gene1513 4.895e-50 188.0 arCOG10603@1|root,32SV6@2|Bacteria,1MYDK@1224|Proteobacteria,1SG7U@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_4507355_5 998674.ATTE01000001_gene3793 2.805e-21 94.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria,46058@72273|Thiotrichales 72273|Thiotrichales C FMN-dependent dehydrogenase - - - - - - - - - - - - FMN_dh CMS3_k127_4507355_6 666509.RCA23_c10230 7.718e-10 63.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases lldD2 - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh CMS3_k127_4507355_0 1121930.AQXG01000011_gene1688 2.5e-323 1004.0 COG1629@1|root,COG4771@2|Bacteria,4NE4M@976|Bacteroidetes,1ISRU@117747|Sphingobacteriia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4509651_2 886293.Sinac_0924 7.342e-27 112.0 COG3119@1|root,COG3119@2|Bacteria,2IWX1@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.8 ko:K01134 ko00600,ko04142,map00600,map04142 - R04856 RC00231 ko00000,ko00001,ko01000 - - - DUF4994,Sulfatase CMS3_k127_4509651_4 1185876.BN8_01995 7.732e-07 52.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_4509651_1 1288963.ADIS_2403 4.555e-220 693.0 COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase betC_2 - - ko:K01138 - - - - ko00000,ko01000 - - - DUF4976,Sulfatase CMS3_k127_4509651_0 243090.RB2663 1.585e-224 707.0 COG3119@1|root,COG3119@2|Bacteria,2IWSZ@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - - ko:K01138 - - - - ko00000,ko01000 - - - Sulfatase CMS3_k127_4509651_3 1121875.KB907548_gene1646 2.923e-19 90.0 COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZK0@117743|Flavobacteriia 976|Bacteroidetes K AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_4514721_3 504728.K649_02690 1.377e-37 144.0 COG3333@1|root,COG3333@2|Bacteria,1WIRN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA CMS3_k127_4514721_2 1211115.ALIQ01000169_gene4026 6.398e-91 310.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TTFX@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TctC CMS3_k127_4514721_0 1121875.KB907549_gene2017 2.886e-178 569.0 COG1914@1|root,COG1914@2|Bacteria 2|Bacteria P metal ion transmembrane transporter activity - - - - - - - - - - - - Nramp CMS3_k127_4514721_4 1111730.ATTM01000001_gene1467 3.173e-09 66.0 2EJDX@1|root,33D4Y@2|Bacteria,4NYVQ@976|Bacteroidetes,1IC1J@117743|Flavobacteriia,2NW0B@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4514721_1 1356852.N008_09965 1.938e-104 355.0 2C1Y9@1|root,2Z8Q2@2|Bacteria,4NI0A@976|Bacteroidetes,47TIH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4518546_3 616991.JPOO01000003_gene1698 1.549e-42 160.0 COG2181@1|root,COG2181@2|Bacteria 2|Bacteria C nitrate reductase activity narI GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 ko:K00370,ko:K00374,ko:K02575 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00615,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.1.8,5.A.3.1 - iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897 Nitrate_red_gam CMS3_k127_4518546_1 1121918.ARWE01000001_gene3009 6.618e-243 758.0 COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,42PGA@68525|delta/epsilon subdivisions,2WU4N@28221|Deltaproteobacteria,43T7F@69541|Desulfuromonadales 28221|Deltaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_4518546_0 1123234.AUKI01000019_gene532 7.451e-283 875.0 COG2223@1|root,COG2223@2|Bacteria,4NJ57@976|Bacteroidetes,1HWYX@117743|Flavobacteriia 976|Bacteroidetes P Transporter - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1,MgtE_N CMS3_k127_4520710_0 761193.Runsl_4304 9.772e-217 694.0 COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47MAT@768503|Cytophagia 976|Bacteroidetes CG Cytochrome c, class I - - - ko:K08738,ko:K09992 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA CMS3_k127_4520710_1 1089547.KB913013_gene2328 1.271e-87 297.0 COG3828@1|root,COG3828@2|Bacteria,4NGR8@976|Bacteroidetes,47P1J@768503|Cytophagia 976|Bacteroidetes S Trehalose utilisation - - - ko:K09992 - - - - ko00000 - - - ThuA CMS3_k127_4520710_2 1121904.ARBP01000010_gene2255 1.948e-85 289.0 28HMY@1|root,2Z7WC@2|Bacteria,4NG8W@976|Bacteroidetes,47Q27@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4524612_0 926562.Oweho_0750 6.255e-179 574.0 COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1HXSG@117743|Flavobacteriia,2PA5D@246874|Cryomorphaceae 976|Bacteroidetes L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 CMS3_k127_4524612_3 468059.AUHA01000004_gene2183 6.381e-96 322.0 COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,1INT7@117747|Sphingobacteriia 976|Bacteroidetes E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS3_k127_4524612_6 1123057.P872_01330 8.664e-13 69.0 2BVK8@1|root,32Y0S@2|Bacteria,4NUUA@976|Bacteroidetes,47RXH@768503|Cytophagia 976|Bacteroidetes S Histone H1-like protein - - - - - - - - - - - - Hc1 CMS3_k127_4524612_1 313606.M23134_05672 2.152e-165 529.0 COG0156@1|root,COG0156@2|Bacteria,4NFRY@976|Bacteroidetes,47KDV@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II - - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_4524612_2 643867.Ftrac_3091 2.632e-108 361.0 28JI8@1|root,2Z9BM@2|Bacteria,4NE5E@976|Bacteroidetes,47JAX@768503|Cytophagia 976|Bacteroidetes S S1 P1 nuclease - - - - - - - - - - - - S1-P1_nuclease,Zn_dep_PLPC CMS3_k127_4524612_5 485918.Cpin_6581 1.569e-29 120.0 COG2127@1|root,COG2127@2|Bacteria,4NS8R@976|Bacteroidetes,1IUIV@117747|Sphingobacteriia 976|Bacteroidetes S Clp protease adaptor protein ClpS clpS - - ko:K06891 - - - - ko00000 - - - ClpS CMS3_k127_4524612_4 1313301.AUGC01000004_gene2290 9.288e-86 289.0 COG2360@1|root,COG2360@2|Bacteria,4NG3A@976|Bacteroidetes 976|Bacteroidetes O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat - 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans CMS3_k127_4524612_7 1123242.JH636435_gene913 2.1e-05 55.0 COG4219@1|root,COG4219@2|Bacteria,2J205@203682|Planctomycetes 203682|Planctomycetes KT BlaR1 peptidase M56 - - - - - - - - - - - - Peptidase_M56,Thioredoxin_7 CMS3_k127_4526386_10 1356852.N008_01580 6.661e-19 96.0 COG2148@1|root,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,47N5W@768503|Cytophagia 976|Bacteroidetes M sugar transferase wcaJ_2 - 2.7.8.6 ko:K00996,ko:K03606 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 CMS3_k127_4526386_9 517418.Ctha_1966 2.709e-43 167.0 COG1905@1|root,COG1905@2|Bacteria,1FEPW@1090|Chlorobi 1090|Chlorobi C Thioredoxin-like [2Fe-2S] ferredoxin - - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx CMS3_k127_4526386_2 313606.M23134_08437 3.666e-155 497.0 COG0505@1|root,COG0505@2|Bacteria,4NEQI@976|Bacteroidetes,47KT4@768503|Cytophagia 976|Bacteroidetes F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CMS3_k127_4526386_7 278963.ATWD01000001_gene3500 1.195e-45 184.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - - PMT_2 CMS3_k127_4526386_0 760192.Halhy_2990 7.607e-286 899.0 COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,4NFGR@976|Bacteroidetes,1IQEK@117747|Sphingobacteriia 976|Bacteroidetes E homoserine dehydrogenase thrA - 1.1.1.3,2.7.2.4 ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3 CMS3_k127_4526386_3 1121957.ATVL01000011_gene3937 3.163e-140 458.0 COG0654@1|root,COG0654@2|Bacteria,4NGIU@976|Bacteroidetes,47KM9@768503|Cytophagia 976|Bacteroidetes H Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid kmo - 1.14.13.9 ko:K00486 ko00380,ko01100,map00380,map01100 M00038 R01960 RC00046 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS3_k127_4526386_8 984262.SGRA_3723 1.453e-44 171.0 COG1427@1|root,COG1427@2|Bacteria,4NN4W@976|Bacteroidetes,1ISCN@117747|Sphingobacteriia 976|Bacteroidetes S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth CMS3_k127_4526386_6 929703.KE386491_gene2422 2.501e-48 180.0 COG0406@1|root,COG0406@2|Bacteria,4NFX5@976|Bacteroidetes,47JSV@768503|Cytophagia 976|Bacteroidetes G phosphoglycerate mutase family gpm - - - - - - - - - - - His_Phos_1 CMS3_k127_4526386_1 1313421.JHBV01000043_gene2978 1.743e-181 574.0 COG1060@1|root,COG1060@2|Bacteria,4NGDN@976|Bacteroidetes,1IPM7@117747|Sphingobacteriia 976|Bacteroidetes H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate mqnE - 2.5.1.120 ko:K18285 ko00130,ko01110,map00130,map01110 - R10667 RC00021,RC03234 ko00000,ko00001,ko01000 - - - Radical_SAM CMS3_k127_4526386_11 1189612.A33Q_0409 0.0002282 50.0 2DMCZ@1|root,32N7D@2|Bacteria,4NS5N@976|Bacteroidetes 976|Bacteroidetes S Uncharacterised protein family (UPF0158) - - - - - - - - - - - - UPF0158 CMS3_k127_4526386_4 616991.JPOO01000001_gene4175 6.878e-122 399.0 COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,1HYX1@117743|Flavobacteriia 976|Bacteroidetes C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2,MaoC_dehydratas CMS3_k127_4526386_5 489825.LYNGBM3L_10730 1.679e-117 387.0 COG2374@1|root,COG2374@2|Bacteria,1G409@1117|Cyanobacteria,1H9FB@1150|Oscillatoriales 1117|Cyanobacteria L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos CMS3_k127_4536314_4 1121373.KB903632_gene414 1.258e-11 76.0 2E0MA@1|root,32W6I@2|Bacteria,4NNWD@976|Bacteroidetes,47Q2K@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_4536314_0 1121373.KB903632_gene415 8.284e-197 650.0 COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,4NEYQ@976|Bacteroidetes,47NKP@768503|Cytophagia 976|Bacteroidetes M WD40 repeats - - - - - - - - - - - - WD40 CMS3_k127_4536314_1 1122621.ATZA01000014_gene3188 6.32e-131 433.0 28KMN@1|root,2ZA61@2|Bacteria,4NJ9P@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - DUF4062 CMS3_k127_4536314_2 886377.Murru_1757 2.468e-69 251.0 COG1278@1|root,COG1278@2|Bacteria,4NUCZ@976|Bacteroidetes 976|Bacteroidetes K Domain of unknown function (DUF3825) - - - - - - - - - - - - DUF3825 CMS3_k127_4536314_3 1286632.P278_33120 2.192e-38 148.0 COG1073@1|root,COG4977@1|root,COG1073@2|Bacteria,COG4977@2|Bacteria,4NFD0@976|Bacteroidetes,1I110@117743|Flavobacteriia 976|Bacteroidetes K Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,HTH_18 CMS3_k127_4540004_1 382464.ABSI01000012_gene2048 4.8e-81 276.0 COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia,2IUUP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S COGs COG4299 conserved - - - - - - - - - - - - - CMS3_k127_4540004_2 1313421.JHBV01000024_gene4945 1.409e-44 169.0 COG1595@1|root,COG1595@2|Bacteria,4NTAA@976|Bacteroidetes 976|Bacteroidetes K COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2 CMS3_k127_4540004_0 1317122.ATO12_08560 6.706e-122 427.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_8 CMS3_k127_4542730_0 760192.Halhy_1519 1.288e-312 989.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - FG-GAP,UnbV_ASPIC,VCBS CMS3_k127_4542730_3 861299.J421_2250 3.674e-176 569.0 COG1435@1|root,COG1435@2|Bacteria 2|Bacteria F thymidine kinase activity tdk - 2.7.1.21 ko:K00857,ko:K21572 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB,TK CMS3_k127_4542730_2 861299.J421_2247 2.571e-239 778.0 COG4206@1|root,COG4206@2|Bacteria 2|Bacteria H cobalamin-transporting ATPase activity - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4542730_1 555500.I215_14511 2.118e-249 779.0 COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1HZ5E@117743|Flavobacteriia 976|Bacteroidetes S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF CMS3_k127_4542730_4 1123277.KB893173_gene1828 7.966e-22 95.0 COG4948@1|root,COG4948@2|Bacteria,4NFHR@976|Bacteroidetes,47KJ8@768503|Cytophagia 976|Bacteroidetes M PFAM Mandelate racemase muconate lactonizing - - 4.2.1.40 ko:K01706 ko00053,ko01100,map00053,map01100 - R02752,R08056 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_4549193_1 313606.M23134_00060 1.322e-16 80.0 COG1154@1|root,COG1154@2|Bacteria,4NDY5@976|Bacteroidetes,47JUB@768503|Cytophagia 976|Bacteroidetes H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,E1_dh,Transket_pyr,Transketolase_C CMS3_k127_4549193_0 468059.AUHA01000002_gene1251 0.0 1178.0 COG0567@1|root,COG0567@2|Bacteria,4NEU9@976|Bacteroidetes,1IQYB@117747|Sphingobacteriia 976|Bacteroidetes C 2-oxoglutarate dehydrogenase, E1 sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr CMS3_k127_455165_4 471854.Dfer_5145 7.246e-25 118.0 COG0457@1|root,COG0457@2|Bacteria,4NG8A@976|Bacteroidetes,47JRE@768503|Cytophagia 976|Bacteroidetes S TPR repeat-containing protein - - - - - - - - - - - - TPR_12,TPR_7,TPR_8 CMS3_k127_455165_0 411154.GFO_1094 1.513e-84 286.0 COG0846@1|root,COG0846@2|Bacteria,4NE9Q@976|Bacteroidetes,1HXX3@117743|Flavobacteriia 976|Bacteroidetes K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 CMS3_k127_455165_3 502025.Hoch_3088 3.273e-26 113.0 COG3255@1|root,COG3255@2|Bacteria,1N0RD@1224|Proteobacteria 1224|Proteobacteria I Sterol carrier protein - - - - - - - - - - - - SCP2 CMS3_k127_455165_5 1089553.Tph_c18890 4.481e-17 92.0 COG1266@1|root,COG1266@2|Bacteria,1UYGJ@1239|Firmicutes,24CIZ@186801|Clostridia 186801|Clostridia S CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_455165_2 573569.F7308_0028 5.879e-48 177.0 COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,460QH@72273|Thiotrichales 72273|Thiotrichales S Protein of unknown function (DUF1415) - - - ko:K09941 - - - - ko00000 - - - DUF1415 CMS3_k127_455165_1 1122179.KB890436_gene1370 1.636e-64 232.0 28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,1INN1@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2851) - - - - - - - - - - - - DUF2851 CMS3_k127_4552778_5 1121895.Q765_10245 7.771e-51 185.0 COG2342@1|root,COG2342@2|Bacteria,4NH17@976|Bacteroidetes,1I03F@117743|Flavobacteriia,2NTJ1@237|Flavobacterium 976|Bacteroidetes G Glycoside-hydrolase family GH114 - - 6.1.1.16 ko:K01884 ko00970,map00970 M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Glyco_hydro_114 CMS3_k127_4552778_1 1122176.KB903543_gene521 2.747e-159 522.0 COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD CMS3_k127_4552778_4 1313421.JHBV01000030_gene2242 1.27e-52 192.0 COG1309@1|root,COG1309@2|Bacteria,4NH7V@976|Bacteroidetes,1IYPY@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_13,TetR_C_4,TetR_N CMS3_k127_4552778_3 1408433.JHXV01000037_gene2552 1.284e-64 231.0 COG2267@1|root,COG2267@2|Bacteria,4PKB9@976|Bacteroidetes,1IJ6A@117743|Flavobacteriia 976|Bacteroidetes I Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4 CMS3_k127_4552778_6 1121904.ARBP01000009_gene4305 8.135e-46 169.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein kdgF - - - - - - - - - - - Cupin_2 CMS3_k127_4552778_0 1121904.ARBP01000011_gene1486 1.63e-178 569.0 COG0673@1|root,COG0673@2|Bacteria,4NGPP@976|Bacteroidetes,47N04@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,TAT_signal CMS3_k127_4552778_2 1121904.ARBP01000005_gene4806 4.71e-85 284.0 COG3408@1|root,COG3408@2|Bacteria,4NHHR@976|Bacteroidetes,47UI7@768503|Cytophagia 976|Bacteroidetes G Bacterial alpha-L-rhamnosidase C-terminal domain - - - - - - - - - - - - Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N CMS3_k127_4559066_2 1121875.KB907546_gene2621 7.49e-154 488.0 COG3119@1|root,COG3119@2|Bacteria,4PKKW@976|Bacteroidetes,1IJC4@117743|Flavobacteriia 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_4559066_1 869213.JCM21142_72630 9.574e-215 673.0 COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,47K09@768503|Cytophagia 976|Bacteroidetes P Ammonium Transporter - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp CMS3_k127_4559066_3 324925.Ppha_0087 5.68e-47 172.0 COG0347@1|root,COG0347@2|Bacteria,1FF5F@1090|Chlorobi 1090|Chlorobi K Belongs to the P(II) protein family - - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II CMS3_k127_4559066_0 760192.Halhy_1321 3.825e-266 835.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1IVS2@117747|Sphingobacteriia 976|Bacteroidetes EU Dienelactone hydrolase family - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_4559066_4 717606.PaecuDRAFT_3944 1.012e-16 80.0 COG1112@1|root,COG1643@1|root,COG1112@2|Bacteria,COG1643@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli,26VZZ@186822|Paenibacillaceae 91061|Bacilli L AAA domain - - - - - - - - - - - - AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559 CMS3_k127_4561143_1 1122176.KB903559_gene4123 1.269e-125 409.0 COG3000@1|root,COG3369@1|root,COG3000@2|Bacteria,COG3369@2|Bacteria,4NIKB@976|Bacteroidetes,1IY4D@117747|Sphingobacteriia 976|Bacteroidetes I PFAM Fatty acid hydroxylase - - - - - - - - - - - - FA_hydroxylase CMS3_k127_4561143_5 509635.N824_15500 3.415e-11 66.0 COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia 976|Bacteroidetes E COG0308 Aminopeptidase N - - - - - - - - - - - - Peptidase_M1 CMS3_k127_4561143_3 649349.Lbys_3458 2.75e-35 141.0 COG4319@1|root,COG4319@2|Bacteria,4NS9D@976|Bacteroidetes,47R8I@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 CMS3_k127_4561143_0 926562.Oweho_2340 9.513e-182 582.0 COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,1HXQH@117743|Flavobacteriia,2PAM6@246874|Cryomorphaceae 976|Bacteroidetes J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c CMS3_k127_4561143_4 518766.Rmar_0092 1.183e-29 130.0 2EDTI@1|root,337NU@2|Bacteria,4P32V@976|Bacteroidetes,1FK0A@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4561143_2 929713.NIASO_17040 7.263e-77 264.0 COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,1INKY@117747|Sphingobacteriia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family crt - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 CMS3_k127_4564074_3 1089545.KB913037_gene2481 3.145e-09 70.0 COG1075@1|root,COG1075@2|Bacteria,2I8WC@201174|Actinobacteria,4EBE8@85010|Pseudonocardiales 201174|Actinobacteria S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - CMS3_k127_4564074_4 743722.Sph21_0441 1.269e-08 56.0 COG1487@1|root,COG1487@2|Bacteria,4P9TF@976|Bacteroidetes,1IZ06@117747|Sphingobacteriia 976|Bacteroidetes S ribonuclease activity - - - - - - - - - - - - - CMS3_k127_4564074_2 251221.35213000 3.11e-11 68.0 COG1487@1|root,COG1487@2|Bacteria 2|Bacteria S nuclease activity - - - ko:K18828 - - - - ko00000,ko01000,ko02048,ko03016 - - - PIN CMS3_k127_4564074_0 1120968.AUBX01000010_gene915 2.403e-166 552.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47P60@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4564074_5 247490.KSU1_D0217 0.000683 47.0 COG1864@1|root,COG1864@2|Bacteria,2J0P4@203682|Planctomycetes 203682|Planctomycetes F DNA/RNA non-specific endonuclease - - - - - - - - - - - - Endonuclease_NS CMS3_k127_4564074_1 1124780.ANNU01000017_gene1927 4.448e-26 116.0 COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes 976|Bacteroidetes M SPTR CHU large protein - - - - - - - - - - - - SprB CMS3_k127_4565173_1 742817.HMPREF9449_02474 1.277e-48 176.0 COG0205@1|root,COG0205@2|Bacteria,4NFPT@976|Bacteroidetes,2FMJ9@200643|Bacteroidia,22ZT1@171551|Porphyromonadaceae 976|Bacteroidetes G Phosphofructokinase - - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK CMS3_k127_4565173_3 1396141.BATP01000036_gene3845 4.855e-16 90.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - FG-GAP_2,PQQ_2 CMS3_k127_4565173_0 1168034.FH5T_05800 1.407e-160 516.0 COG4225@1|root,COG4225@2|Bacteria,4NMD6@976|Bacteroidetes,2FR8I@200643|Bacteroidia 976|Bacteroidetes N BNR repeat-containing family member - - - - - - - - - - - - BNR_4 CMS3_k127_4565173_2 313606.M23134_01171 1.115e-16 86.0 COG4191@1|root,COG4191@2|Bacteria,4NIIP@976|Bacteroidetes,47MXS@768503|Cytophagia 976|Bacteroidetes T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA,cNMP_binding CMS3_k127_4566808_1 313606.M23134_04956 2.204e-37 145.0 COG2220@1|root,COG2220@2|Bacteria,4NFJ4@976|Bacteroidetes,47JCF@768503|Cytophagia 976|Bacteroidetes S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 CMS3_k127_4566808_0 1121904.ARBP01000018_gene2691 8.191e-260 828.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4P00W@976|Bacteroidetes,47TWW@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS3_k127_4569704_1 1122176.KB903554_gene3790 2.255e-139 459.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_4569704_0 313606.M23134_04119 1.033e-150 487.0 COG2865@1|root,COG2865@2|Bacteria,4NHJM@976|Bacteroidetes,47X5V@768503|Cytophagia 976|Bacteroidetes K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,HTH_11,HTH_24 CMS3_k127_4569704_2 1123276.KB893290_gene5208 7.293e-10 61.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NJ2Y@976|Bacteroidetes,47N0D@768503|Cytophagia 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,HisKA_2,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_4575798_3 688270.Celal_0480 9.505e-38 149.0 COG2259@1|root,COG2259@2|Bacteria,4NGNF@976|Bacteroidetes,1HXE7@117743|Flavobacteriia,1F8P2@104264|Cellulophaga 976|Bacteroidetes S DoxX doxX - - - - - - - - - - - DoxX CMS3_k127_4575798_4 929556.Solca_0685 4.171e-27 115.0 COG0681@1|root,COG0681@2|Bacteria,4NSIR@976|Bacteroidetes,1ITMV@117747|Sphingobacteriia 976|Bacteroidetes U Belongs to the peptidase S26 family - - - - - - - - - - - - - CMS3_k127_4575798_2 1408473.JHXO01000007_gene966 4.168e-60 225.0 COG0204@1|root,COG0204@2|Bacteria,4NN7X@976|Bacteroidetes,2FUAF@200643|Bacteroidia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_4575798_1 1121104.AQXH01000005_gene197 4.683e-93 314.0 COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes 976|Bacteroidetes S Sodium bile acid symporter family - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF CMS3_k127_4575798_0 926549.KI421517_gene3691 2.408e-162 518.0 COG0346@1|root,COG0346@2|Bacteria,4NDVG@976|Bacteroidetes,47MTQ@768503|Cytophagia 976|Bacteroidetes E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase,Glyoxalase_4 CMS3_k127_4578816_0 649349.Lbys_0684 4.814e-25 118.0 COG3656@1|root,COG3656@2|Bacteria,4NHDQ@976|Bacteroidetes,47PJR@768503|Cytophagia 976|Bacteroidetes G Fibronectin type III domain protein - - - ko:K21571 - - - - ko00000 - - - - CMS3_k127_4578816_1 742740.HMPREF9474_02707 6.144e-08 64.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,21XSZ@1506553|Lachnoclostridium 186801|Clostridia O PDZ DHR GLGF domain protein degQ - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 CMS3_k127_4579060_0 1267535.KB906767_gene5299 3.756e-100 335.0 COG1073@1|root,COG3250@1|root,COG1073@2|Bacteria,COG3250@2|Bacteria,3Y652@57723|Acidobacteria 57723|Acidobacteria G alpha beta - - - - - - - - - - - - - CMS3_k127_4579060_2 1121904.ARBP01000006_gene3746 1.77e-71 246.0 COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,47PSE@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_4579060_3 1250278.JQNQ01000001_gene2044 1.424e-38 158.0 COG4861@1|root,COG4861@2|Bacteria,4NK3Z@976|Bacteroidetes,1I1QK@117743|Flavobacteriia 976|Bacteroidetes S Transcriptional regulator, AbiEi antitoxin, Type IV TA system - - - - - - - - - - - - AbiEi_2 CMS3_k127_4579060_4 1122179.KB890443_gene1211 2.521e-16 80.0 COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia 976|Bacteroidetes K Tetratricopeptide repeat - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_16,TPR_8 CMS3_k127_4579060_1 1358423.N180_03655 1.95e-79 269.0 COG1373@1|root,COG1373@2|Bacteria,4NHQG@976|Bacteroidetes,1IUTK@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_4579121_1 1121904.ARBP01000011_gene1412 4.266e-109 357.0 COG3119@1|root,COG3119@2|Bacteria,4NHFD@976|Bacteroidetes,47TGB@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_4579121_0 1408433.JHXV01000005_gene2399 1.537e-141 458.0 COG0457@1|root,COG0457@2|Bacteria,4NJJ8@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4915) - - - - - - - - - - - - DUF4915 CMS3_k127_4579121_2 765913.ThidrDRAFT_4649 1.141e-84 297.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S1HJ@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Cadherin,Cadherin_3,DUF4214,DUF4347,He_PIG,HemolysinCabind,PATR,VCBS CMS3_k127_4579121_3 240292.Ava_2971 4.295e-68 252.0 COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HKN5@1161|Nostocales 1117|Cyanobacteria S PFAM WD domain, G-beta repeat - - - - - - - - - - - - AAA_35,WD40 CMS3_k127_4579121_5 700598.Niako_3252 5.565e-08 55.0 2AF5J@1|root,3154E@2|Bacteria,4PJCB@976|Bacteroidetes,1J00D@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4907) - - - - - - - - - - - - DUF4907 CMS3_k127_4590656_2 1042163.BRLA_c039450 4.317e-16 79.0 COG0528@1|root,COG0528@2|Bacteria,1U09A@1239|Firmicutes,4HBRM@91061|Bacilli,26QVG@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase CMS3_k127_4590656_0 649831.L083_3500 8.222e-36 151.0 COG3629@1|root,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria 201174|Actinobacteria K Bacterial transcriptional activator domain - - - - - - - - - - - - BTAD,Trans_reg_C CMS3_k127_4590656_1 222534.KB893672_gene2959 1.136e-31 139.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria,4EWVP@85013|Frankiales 201174|Actinobacteria K Bacterial transcriptional activator domain - - - - - - - - - - - - BTAD,Trans_reg_C CMS3_k127_4592656_0 1121904.ARBP01000016_gene5220 9.573e-290 909.0 COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia 976|Bacteroidetes Q PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 CMS3_k127_4592656_1 1121904.ARBP01000016_gene5221 4.367e-35 138.0 COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 CMS3_k127_4601842_0 1313301.AUGC01000012_gene1356 2.133e-287 893.0 COG0445@1|root,COG0445@2|Bacteria,4NFNH@976|Bacteroidetes 976|Bacteroidetes D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc CMS3_k127_4601842_1 1168034.FH5T_09720 1.45e-23 116.0 COG1807@1|root,COG1807@2|Bacteria,4NYPX@976|Bacteroidetes 976|Bacteroidetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 CMS3_k127_4602851_0 641524.ADICYQ_3332 2.059e-144 472.0 COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47UGB@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_4602851_2 1291050.JAGE01000002_gene3422 5.151e-70 242.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia,3WGMJ@541000|Ruminococcaceae 186801|Clostridia S PFAM metal-dependent phosphohydrolase HD sub domain yfbR - 3.1.3.89 ko:K07023,ko:K08722 ko00240,ko01100,map00240,map01100 - R01569,R01664,R01968,R02088,R02102,R10776 RC00017 ko00000,ko00001,ko01000 - - - HD_2,HD_3 CMS3_k127_4602851_4 313603.FB2170_00670 1.337e-52 194.0 COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,1HYH2@117743|Flavobacteriia,2PH0M@252356|Maribacter 976|Bacteroidetes G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_4602851_3 1121904.ARBP01000009_gene4328 2.805e-64 244.0 COG4219@1|root,COG4219@2|Bacteria,4NKKC@976|Bacteroidetes,47JQV@768503|Cytophagia 976|Bacteroidetes KT PFAM Peptidase M56, BlaR1 - - - - - - - - - - - - Peptidase_M56 CMS3_k127_4602851_5 929556.Solca_0387 2.137e-38 149.0 COG3682@1|root,COG3682@2|Bacteria,4NSQR@976|Bacteroidetes,1ISTV@117747|Sphingobacteriia 976|Bacteroidetes K Transcriptional repressor, CopY family - - - - - - - - - - - - Penicillinase_R CMS3_k127_4602851_1 313606.M23134_00150 1.966e-109 364.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,47K61@768503|Cytophagia 976|Bacteroidetes I AMP-binding enzyme - - - - - - - - - - - - AMP-binding CMS3_k127_4606536_2 1408473.JHXO01000016_gene1926 8.355e-74 262.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,2G2X1@200643|Bacteroidia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_7,TPR_8 CMS3_k127_4606536_1 1048983.EL17_01565 5.616e-195 632.0 COG2217@1|root,COG2217@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia 976|Bacteroidetes P ATPase, P-type (transporting), HAD superfamily, subfamily IC ccoI - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase CMS3_k127_4606536_3 926562.Oweho_2084 7.258e-10 65.0 COG3197@1|root,COG3197@2|Bacteria,4NUR7@976|Bacteroidetes,1I562@117743|Flavobacteriia,2PB7Y@246874|Cryomorphaceae 976|Bacteroidetes P TIGRFAM cytochrome oxidase maturation protein, cbb3-type ccoS - - - - - - - - - - - FixS CMS3_k127_4606536_0 1122176.KB903609_gene5126 3.611e-260 806.0 COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,1IP6D@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the heme-copper respiratory oxidase family ccoN - 1.9.3.1 ko:K15862 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1,FixO CMS3_k127_4613911_0 1279009.ADICEAN_03159 1.414e-236 756.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47MGE@768503|Cytophagia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - FG-GAP,UnbV_ASPIC,VCBS CMS3_k127_4629227_3 394503.Ccel_2352 1.714e-53 202.0 COG0494@1|root,COG0535@1|root,COG0494@2|Bacteria,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae 186801|Clostridia C Radical SAM domain protein - - - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,NUDIX,PqqD,Radical_SAM,SPASM CMS3_k127_4629227_5 1430440.MGMSRv2_4194 2.145e-30 133.0 COG0535@1|root,COG0535@2|Bacteria,1PSG1@1224|Proteobacteria,2V4N0@28211|Alphaproteobacteria,2JWSV@204441|Rhodospirillales 204441|Rhodospirillales C Radical SAM superfamily - - - - - - - - - - - - Radical_SAM CMS3_k127_4629227_2 755731.Clo1100_2798 2.665e-95 328.0 COG1032@1|root,COG1032@2|Bacteria,1V8ME@1239|Firmicutes,25CH1@186801|Clostridia 186801|Clostridia C Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM CMS3_k127_4629227_6 1122176.KB903587_gene4549 3.635e-11 64.0 COG3507@1|root,COG3507@2|Bacteria,4NFXE@976|Bacteroidetes,1IR2U@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 43 family xynBA - - - - - - - - - - - Glyco_hydro_43 CMS3_k127_4629227_0 760192.Halhy_3745 6.888e-182 586.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NIKG@976|Bacteroidetes,1IWUH@117747|Sphingobacteriia 976|Bacteroidetes C Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Cytochrom_C,GSDH CMS3_k127_4629227_7 762903.Pedsa_3355 3.861e-08 56.0 COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1IP71@117747|Sphingobacteriia 976|Bacteroidetes G Pectate lyase - - - - - - - - - - - - - CMS3_k127_4629227_1 388413.ALPR1_05970 3.235e-169 551.0 COG3264@1|root,COG3264@2|Bacteria,4PMEF@976|Bacteroidetes,47P1K@768503|Cytophagia 976|Bacteroidetes M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel CMS3_k127_4629227_8 56110.Oscil6304_4527 0.0007563 44.0 COG0745@1|root,COG2114@1|root,COG4252@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG4252@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - ko:K19694 - - - - ko00000,ko01001,ko02022 - - - 7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1 CMS3_k127_4629227_4 1122176.KB903533_gene2432 2.073e-43 161.0 COG2755@1|root,COG2755@2|Bacteria,4NKE5@976|Bacteroidetes,1IXCA@117747|Sphingobacteriia 976|Bacteroidetes E PFAM GDSL-like Lipase Acylhydrolase rhgT_1 - - - - - - - - - - - Lipase_GDSL_2 CMS3_k127_4648923_1 313606.M23134_00703 8.189e-88 295.0 COG2303@1|root,COG2303@2|Bacteria,4NI42@976|Bacteroidetes,47MET@768503|Cytophagia 976|Bacteroidetes E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N CMS3_k127_4648923_0 1313301.AUGC01000005_gene251 1.037e-147 478.0 COG0018@1|root,COG0018@2|Bacteria,4NE7Q@976|Bacteroidetes 976|Bacteroidetes J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d CMS3_k127_4650682_3 1122176.KB903556_gene4105 4.975e-21 95.0 COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,1IQIN@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 CMS3_k127_4650682_0 1356852.N008_07180 1.87e-169 548.0 COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_4650682_2 1408473.JHXO01000010_gene3714 1.515e-51 200.0 COG3307@1|root,COG3307@2|Bacteria,4NMYT@976|Bacteroidetes 976|Bacteroidetes M O-Antigen ligase - - - - - - - - - - - - Wzy_C CMS3_k127_4650682_1 926562.Oweho_0901 1.23e-92 312.0 COG0673@1|root,COG0673@2|Bacteria,4NEC6@976|Bacteroidetes,1HXSP@117743|Flavobacteriia,2PA4G@246874|Cryomorphaceae 976|Bacteroidetes S PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_4656505_0 391603.FBALC1_16772 5.9e-95 330.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_4658010_0 1121904.ARBP01000095_gene1599 3.698e-188 600.0 COG4584@1|root,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,47MFD@768503|Cytophagia 976|Bacteroidetes L PFAM integrase - - - - - - - - - - - - HTH_11,HTH_23,rve CMS3_k127_4658010_1 1121904.ARBP01000095_gene1598 3.124e-122 395.0 COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,47P7E@768503|Cytophagia 976|Bacteroidetes L PFAM IstB domain protein ATP-binding protein - - - - - - - - - - - - IstB_IS21 CMS3_k127_4660778_1 1304888.ATWF01000001_gene2463 5.926e-32 129.0 COG1922@1|root,COG1922@2|Bacteria,2GGME@200930|Deferribacteres 200930|Deferribacteres M Glycosyl transferase WecB/TagA/CpsF family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB CMS3_k127_4660778_0 349521.HCH_02732 1.941e-94 335.0 COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,1XJ7M@135619|Oceanospirillales 135619|Oceanospirillales I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 CMS3_k127_4660778_2 314285.KT71_12295 9.711e-12 65.0 COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S7JE@1236|Gammaproteobacteria,1JBZ2@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - - - - - - - - - - HTH_Tnp_1 CMS3_k127_4682227_0 1122621.ATZA01000019_gene4320 6.666e-208 681.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,1IP7W@117747|Sphingobacteriia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG CMS3_k127_4682227_1 530564.Psta_1560 5.593e-81 286.0 2EW1S@1|root,33PF1@2|Bacteria,2J1T5@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - CMS3_k127_4682227_2 385682.AFSL01000062_gene1615 4.228e-27 119.0 2CI1G@1|root,2Z7JA@2|Bacteria,4NF1T@976|Bacteroidetes,2FPFD@200643|Bacteroidia,3XJ9A@558415|Marinilabiliaceae 976|Bacteroidetes S Domain of unknown function (DUF4294) - - - - - - - - - - - - DUF4294 CMS3_k127_4682227_3 153721.MYP_2257 1.373e-06 50.0 COG2030@1|root,COG2030@2|Bacteria,4NPYH@976|Bacteroidetes,47PSF@768503|Cytophagia 976|Bacteroidetes I MaoC domain protein dehydratase maoC - 4.2.1.55 ko:K17865 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R03027 RC00831 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydratas CMS3_k127_4686858_3 880071.Fleli_3297 2.193e-19 104.0 COG0515@1|root,COG5263@1|root,COG0515@2|Bacteria,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,47PRU@768503|Cytophagia 976|Bacteroidetes KLT WG containing repeat - - - - - - - - - - - - OMP_b-brl_2,WG_beta_rep CMS3_k127_4686858_2 1173028.ANKO01000005_gene2246 3.701e-41 175.0 COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales 1117|Cyanobacteria A Wd40 repeat-containing protein - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - AAA_35,Peptidase_C14,TIR_2,TPR_8,WD40 CMS3_k127_4686858_1 1123278.KB893433_gene621 5.575e-43 161.0 COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 CMS3_k127_4686858_0 1304874.JAFY01000002_gene895 6.656e-123 405.0 COG0624@1|root,COG0624@2|Bacteria,3TBDJ@508458|Synergistetes 508458|Synergistetes E Peptidase dimerisation domain - - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 CMS3_k127_4686858_5 1168289.AJKI01000002_gene2477 1.562e-12 70.0 2CJWB@1|root,32P4S@2|Bacteria,4NQ5Z@976|Bacteroidetes,2FXKX@200643|Bacteroidia,3XK2X@558415|Marinilabiliaceae 976|Bacteroidetes - - - - - - - - - - - - - - Abi CMS3_k127_4686858_4 1120968.AUBX01000009_gene277 2.325e-13 72.0 COG1950@1|root,COG1950@2|Bacteria,4NT2I@976|Bacteroidetes,47S20@768503|Cytophagia 976|Bacteroidetes S PFAM Membrane protein of yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 CMS3_k127_4690514_1 929703.KE386491_gene898 1.741e-33 146.0 COG0457@1|root,COG0457@2|Bacteria,4NJ7X@976|Bacteroidetes,47NJZ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_8 CMS3_k127_4690514_0 1279009.ADICEAN_03941 1.838e-38 160.0 COG0515@1|root,COG0515@2|Bacteria,4NMTE@976|Bacteroidetes,47X9Z@768503|Cytophagia 976|Bacteroidetes KLT Protein tyrosine kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase CMS3_k127_4694571_1 984262.SGRA_3699 3.19e-75 262.0 COG0508@1|root,COG0508@2|Bacteria,4NED0@976|Bacteroidetes,1IP3U@117747|Sphingobacteriia 976|Bacteroidetes C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS3_k127_4694571_2 926549.KI421517_gene3055 9.227e-73 260.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,47JN4@768503|Cytophagia 976|Bacteroidetes S CinA-like protein cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth CMS3_k127_4694571_0 203124.Tery_1252 2.487e-86 296.0 COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria,1H7D3@1150|Oscillatoriales 1117|Cyanobacteria P K -dependent Na Ca exchanger - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex CMS3_k127_4694571_4 485918.Cpin_7286 2.714e-09 66.0 2AFPJ@1|root,315RB@2|Bacteria,4PJWT@976|Bacteroidetes,1IUP5@117747|Sphingobacteriia 976|Bacteroidetes S Sporulation related domain - - - - - - - - - - - - SPOR CMS3_k127_4694571_3 1408433.JHXV01000015_gene1718 1.31e-14 78.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - CHU_C,PKD,SprB CMS3_k127_4698711_2 531844.FIC_01705 8.035e-05 51.0 COG3212@1|root,COG3212@2|Bacteria,4NTGN@976|Bacteroidetes,1II7H@117743|Flavobacteriia 976|Bacteroidetes S Putative beta-lactamase-inhibitor-like, PepSY-like - - - - - - - - - - - - PepSY_like CMS3_k127_4698711_0 313603.FB2170_14803 5.916e-106 349.0 COG1142@1|root,COG1142@2|Bacteria 2|Bacteria C 4 iron, 4 sulfur cluster binding - - - - - - - - - - - - Fer4_10,Fer4_7,Fer4_9,Pyr_redox_2,Pyr_redox_3,cNMP_binding CMS3_k127_4698711_1 313603.FB2170_14808 1.006e-65 228.0 COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,4NDVS@976|Bacteroidetes,1HXB3@117743|Flavobacteriia 976|Bacteroidetes O PFAM Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Fer4_10,Pyr_redox_3 CMS3_k127_4699447_1 1296416.JACB01000029_gene4243 1.136e-74 253.0 COG3832@1|root,COG3832@2|Bacteria,4NR9F@976|Bacteroidetes,1IGFV@117743|Flavobacteriia,2YHDA@290174|Aquimarina 976|Bacteroidetes S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 CMS3_k127_4699447_2 1296416.JACB01000029_gene4242 1.137e-48 175.0 COG0640@1|root,COG0640@2|Bacteria,4NTCN@976|Bacteroidetes,1IJ3T@117743|Flavobacteriia,2YM5I@290174|Aquimarina 976|Bacteroidetes K Sugar-specific transcriptional regulator TrmB - - - - - - - - - - - - HTH_20,HTH_5 CMS3_k127_4699447_0 1122176.KB903581_gene4358 2.418e-243 773.0 COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,1IQCN@117747|Sphingobacteriia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - ko:K02014,ko:K16089 - - - - ko00000,ko02000 1.B.14,1.B.14.1,1.B.14.10 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4714999_3 760192.Halhy_1218 6.497e-184 585.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_4714999_5 1121481.AUAS01000013_gene4150 2.682e-119 388.0 COG2755@1|root,COG2755@2|Bacteria,4PN35@976|Bacteroidetes,47Y83@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_4714999_4 555500.I215_13193 8.943e-152 492.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1I6TA@117743|Flavobacteriia 976|Bacteroidetes S ATPase domain predominantly from Archaea - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 CMS3_k127_4714999_1 926549.KI421517_gene1092 4.459e-231 732.0 COG3420@1|root,COG3420@2|Bacteria,4P1XP@976|Bacteroidetes,47UIA@768503|Cytophagia 976|Bacteroidetes P Parallel beta-helix repeats - - - - - - - - - - - - - CMS3_k127_4714999_2 344747.PM8797T_03650 3.231e-213 674.0 COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes 203682|Planctomycetes E sialic acid-specific 9-O-acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA CMS3_k127_4714999_0 926549.KI421517_gene1787 5.561e-253 788.0 COG4948@1|root,COG4948@2|Bacteria,4NE9A@976|Bacteroidetes,47NDY@768503|Cytophagia 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_4714999_6 1408433.JHXV01000048_gene3348 4.931e-12 67.0 COG5499@1|root,COG5499@2|Bacteria,4NNXF@976|Bacteroidetes,1I2MM@117743|Flavobacteriia 976|Bacteroidetes K transcription regulator containing HTH domain - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3 CMS3_k127_4728891_1 313606.M23134_01222 2.209e-62 222.0 COG0477@1|root,COG2814@2|Bacteria,4PMD0@976|Bacteroidetes,47V52@768503|Cytophagia 976|Bacteroidetes EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_4728891_0 153721.MYP_3589 3.298e-206 661.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,47MZQ@768503|Cytophagia 976|Bacteroidetes M Transglycosylase - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS3_k127_4731962_2 1117108.PAALTS15_29036 3.315e-20 96.0 COG2312@1|root,COG2312@2|Bacteria,1V2D8@1239|Firmicutes,4HGGF@91061|Bacilli,26V4T@186822|Paenibacillaceae 91061|Bacilli S Erythromycin esterase - - - ko:K06880 - - - - ko00000,ko01000,ko01504 - - - Erythro_esteras CMS3_k127_4731962_0 1123277.KB893181_gene2301 7.388e-131 426.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - 3.1.1.23 ko:K01054 ko00561,ko01100,ko04714,ko04723,ko04923,map00561,map01100,map04714,map04723,map04923 M00098 R01351 RC00020,RC00041 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Hydrolase_4 CMS3_k127_4731962_1 641524.ADICYQ_1413 5.354e-37 140.0 28K6N@1|root,2Z9V2@2|Bacteria,4NKJ8@976|Bacteroidetes,47TQ1@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4735542_1 688270.Celal_4198 4.409e-73 251.0 COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia,1F8SU@104264|Cellulophaga 976|Bacteroidetes P COGs COG4771 Outer membrane receptor for ferrienterochelin and colicins - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4735542_0 385682.AFSL01000053_gene498 0.0 1169.0 COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,2FPJG@200643|Bacteroidia,3XJ8Q@558415|Marinilabiliaceae 976|Bacteroidetes J Valyl tRNA synthetase tRNA binding arm valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 CMS3_k127_4735542_3 694427.Palpr_2116 0.0004248 49.0 COG3656@1|root,COG4886@1|root,COG3656@2|Bacteria,COG4886@2|Bacteria,4NHDQ@976|Bacteroidetes,2FTSH@200643|Bacteroidia,22Y91@171551|Porphyromonadaceae 976|Bacteroidetes S Fibronectin type 3 domain - - - ko:K21571 - - - - ko00000 - - - - CMS3_k127_4735542_2 700598.Niako_6917 6.532e-66 251.0 COG2972@1|root,COG4251@1|root,COG2972@2|Bacteria,COG4251@2|Bacteria,4NK9V@976|Bacteroidetes,1IW45@117747|Sphingobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 CMS3_k127_4744488_5 1128912.GMES_0487 4.381e-07 62.0 COG0265@1|root,COG0265@2|Bacteria,1QQUT@1224|Proteobacteria,1SKY0@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 CMS3_k127_4744488_3 760192.Halhy_0251 2.586e-15 90.0 2E9WY@1|root,3342P@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4744488_0 616991.JPOO01000001_gene3939 3.264e-309 964.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HX4Y@117743|Flavobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_4744488_1 760192.Halhy_6015 3.472e-60 214.0 COG2253@1|root,COG2253@2|Bacteria,4NKE9@976|Bacteroidetes,1IRWJ@117747|Sphingobacteriia 976|Bacteroidetes S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii CMS3_k127_4744488_4 457424.BFAG_04841 4.266e-08 58.0 COG3093@1|root,COG3093@2|Bacteria,4NMVH@976|Bacteroidetes,2FUY6@200643|Bacteroidia,4AU5B@815|Bacteroidaceae 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 CMS3_k127_4744488_2 1408433.JHXV01000042_gene1444 1.385e-25 121.0 COG3209@1|root,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ6N@117743|Flavobacteriia,2PC6H@246874|Cryomorphaceae 976|Bacteroidetes M SPTR CHU large protein - - - - - - - - - - - - CHU_C,SprB CMS3_k127_4745881_1 1408433.JHXV01000027_gene3728 6.903e-93 330.0 COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia 976|Bacteroidetes KT regulator - - - - - - - - - - - - GerE,Reg_prop,Y_Y_Y CMS3_k127_4745881_2 251229.Chro_1883 2.332e-79 290.0 COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_8,PG_binding_1,Response_reg,dCache_1 CMS3_k127_4745881_3 1150599.MPHLEI_12401 6.666e-68 240.0 COG3315@1|root,COG3315@2|Bacteria,2GNGD@201174|Actinobacteria,234ZU@1762|Mycobacteriaceae 201174|Actinobacteria H Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - - - - - - - - - - LCM CMS3_k127_4745881_0 1123234.AUKI01000011_gene1285 2.799e-150 488.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia 976|Bacteroidetes Q COG1228 Imidazolonepropionase and related - - - - - - - - - - - - Amidohydro_1 CMS3_k127_4755104_0 485917.Phep_3831 7.692e-274 897.0 COG1747@1|root,COG1747@2|Bacteria,4NEB8@976|Bacteroidetes,1INS4@117747|Sphingobacteriia 976|Bacteroidetes S Motility related/secretion protein sprA - - - - - - - - - - - SprA_N CMS3_k127_4755104_1 865937.Gilli_1907 1.137e-11 65.0 COG5499@1|root,COG5499@2|Bacteria,4NNXF@976|Bacteroidetes,1I2MM@117743|Flavobacteriia 976|Bacteroidetes K transcription regulator containing HTH domain - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3 CMS3_k127_4755530_5 111781.Lepto7376_0575 8.725e-05 54.0 2EG4Q@1|root,339WQ@2|Bacteria,1GH2Z@1117|Cyanobacteria,1HGVT@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_4755530_1 1237149.C900_01584 6.242e-174 555.0 COG1228@1|root,COG1228@2|Bacteria,4NE5U@976|Bacteroidetes,47M6X@768503|Cytophagia 976|Bacteroidetes Q PFAM Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_4755530_0 1237149.C900_01585 4.109e-212 666.0 COG1228@1|root,COG1228@2|Bacteria,4NF27@976|Bacteroidetes,47JC0@768503|Cytophagia 976|Bacteroidetes Q PFAM amidohydrolase - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 CMS3_k127_4755530_3 760192.Halhy_2377 4.269e-139 463.0 COG1228@1|root,COG1228@2|Bacteria,4NHGA@976|Bacteroidetes,1IWA0@117747|Sphingobacteriia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_4755530_4 313606.M23134_04369 5.795e-27 113.0 COG0713@1|root,COG0713@2|Bacteria,4NSR8@976|Bacteroidetes,47R5R@768503|Cytophagia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 CMS3_k127_4755530_2 926549.KI421517_gene2997 2.352e-151 495.0 COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,47M8Q@768503|Cytophagia 976|Bacteroidetes CP NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N CMS3_k127_4756446_4 926549.KI421517_gene4037 0.0004502 50.0 COG3391@1|root,COG3391@2|Bacteria,4NSPG@976|Bacteroidetes,47V9V@768503|Cytophagia 976|Bacteroidetes O Protein conserved in bacteria - - - - - - - - - - - - - CMS3_k127_4756446_3 1237149.C900_04426 0.0002502 51.0 COG1404@1|root,COG2133@1|root,COG2374@1|root,COG3291@1|root,COG3468@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3468@2|Bacteria,COG5492@2|Bacteria,4NJU9@976|Bacteroidetes,47NEJ@768503|Cytophagia 976|Bacteroidetes Q cell adhesion involved in biofilm formation - - - - - - - - - - - - Big_5,PKD CMS3_k127_4756446_0 760192.Halhy_3775 1.224e-265 840.0 COG1529@1|root,COG1529@2|Bacteria,4NG6Q@976|Bacteroidetes 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 CMS3_k127_4756446_1 388413.ALPR1_02070 2.801e-72 247.0 COG2080@1|root,COG2080@2|Bacteria,4NPVY@976|Bacteroidetes 976|Bacteroidetes C [2Fe-2S] binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_4756446_2 880071.Fleli_0899 2.132e-31 130.0 COG1011@1|root,COG1011@2|Bacteria,4P0SE@976|Bacteroidetes,47W6F@768503|Cytophagia 976|Bacteroidetes S HAD-hyrolase-like - - - - - - - - - - - - HAD_2 CMS3_k127_47607_1 1168034.FH5T_12340 4.906e-23 102.0 28HQ3@1|root,2Z7XW@2|Bacteria,4NF9H@976|Bacteroidetes,2FPMP@200643|Bacteroidia 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF2851 CMS3_k127_47607_0 1121904.ARBP01000013_gene449 4.757e-52 188.0 2DVQJ@1|root,32UZZ@2|Bacteria,4P9HJ@976|Bacteroidetes,47RBJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_47607_2 269798.CHU_0078 5.099e-22 110.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 CMS3_k127_4777372_1 760192.Halhy_2973 1.121e-70 256.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_4777372_0 1122176.KB903554_gene3790 2.914e-199 673.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes 976|Bacteroidetes T histidine kinase-, DNA gyrase B - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_4778619_2 760192.Halhy_4332 3.742e-30 125.0 COG1262@1|root,COG1672@1|root,COG3064@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,COG3064@2|Bacteria,4PN7M@976|Bacteroidetes,1IXXU@117747|Sphingobacteriia 976|Bacteroidetes M Membrane - - - - - - - - - - - - - CMS3_k127_4778619_1 760192.Halhy_5532 1.671e-46 181.0 2AHAR@1|root,317M3@2|Bacteria,4P8RB@976|Bacteroidetes,1IZUZ@117747|Sphingobacteriia 760192.Halhy_5532|- S IMG reference gene - - - - - - - - - - - - - CMS3_k127_4778619_3 1549858.MC45_10760 2.417e-08 62.0 2DF6E@1|root,32U4S@2|Bacteria,1N20C@1224|Proteobacteria,2UFPS@28211|Alphaproteobacteria,2K424@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - CMS3_k127_4778619_0 1121904.ARBP01000004_gene1050 3.913e-152 488.0 COG2730@1|root,COG2730@2|Bacteria,4NJFV@976|Bacteroidetes,47S3D@768503|Cytophagia 976|Bacteroidetes G Cellulase (glycosyl hydrolase family 5) celC - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase CMS3_k127_4778619_4 760192.Halhy_1668 7.199e-06 51.0 2DDUQ@1|root,2ZJCQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4808689_3 929703.KE386491_gene4202 1.249e-11 68.0 COG2834@1|root,COG2834@2|Bacteria,4NHV3@976|Bacteroidetes,47K73@768503|Cytophagia 976|Bacteroidetes M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - DUF4292,LolA_like CMS3_k127_4808689_2 1237149.C900_00528 4.918e-27 120.0 COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes,47N83@768503|Cytophagia 976|Bacteroidetes K Crp-like helix-turn-helix domain - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding CMS3_k127_4808689_1 1121481.AUAS01000002_gene3229 5.227e-34 137.0 COG0664@1|root,COG0664@2|Bacteria,4NIP0@976|Bacteroidetes,47PQT@768503|Cytophagia 976|Bacteroidetes T cyclic nucleotide-binding - - - - - - - - - - - - cNMP_binding CMS3_k127_4808689_0 1313421.JHBV01000016_gene5515 1.023e-175 561.0 COG2072@1|root,COG2072@2|Bacteria,4NGC0@976|Bacteroidetes,1ITWD@117747|Sphingobacteriia 976|Bacteroidetes P flavoprotein involved in K transport - - 1.14.13.148 ko:K18277 ko00680,map00680 - R05623 RC00058 ko00000,ko00001,ko01000 - - - FMO-like CMS3_k127_4808689_4 439235.Dalk_1399 9.682e-08 56.0 COG4221@1|root,COG4221@2|Bacteria,1R08W@1224|Proteobacteria,43CRM@68525|delta/epsilon subdivisions 1224|Proteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - adh_short CMS3_k127_4809895_2 1227739.Hsw_1281 1.332e-10 66.0 COG4677@1|root,COG4886@1|root,COG4677@2|Bacteria,COG4886@2|Bacteria 2|Bacteria S regulation of response to stimulus - - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Big_2,Laminin_G_3,fn3 CMS3_k127_4809895_0 313606.M23134_04764 5.198e-123 399.0 COG1028@1|root,COG1028@2|Bacteria,4NIAZ@976|Bacteroidetes,47TIU@768503|Cytophagia 976|Bacteroidetes IQ KR domain - - - ko:K13775 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short CMS3_k127_4809895_1 1089550.ATTH01000001_gene1787 1.895e-31 141.0 COG1404@1|root,COG2911@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,4NJMC@976|Bacteroidetes 976|Bacteroidetes O Belongs to the peptidase S8 family - - - - - - - - - - - - - CMS3_k127_4809895_3 929556.Solca_0737 9.528e-06 58.0 COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IR0W@117747|Sphingobacteriia 976|Bacteroidetes G Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - CHU_C,PKD,SASA CMS3_k127_4815839_0 762903.Pedsa_0610 1.343e-122 400.0 COG0463@1|root,COG0463@2|Bacteria,4NEVT@976|Bacteroidetes,1IPAW@117747|Sphingobacteriia 976|Bacteroidetes M glycosyl transferase family 2 arnC - - - - - - - - - - - Glycos_transf_2 CMS3_k127_4815839_1 1347342.BN863_25070 2.919e-68 241.0 COG3876@1|root,COG3876@2|Bacteria,4NEXD@976|Bacteroidetes,1HWQT@117743|Flavobacteriia 976|Bacteroidetes S protein conserved in bacteria - - - - - - - - - - - - DUF1343 CMS3_k127_4821967_1 742817.HMPREF9449_00780 7.817e-09 64.0 COG1470@1|root,COG1470@2|Bacteria,4PNYS@976|Bacteroidetes,2FQ8P@200643|Bacteroidia 976|Bacteroidetes S PEGA domain - - - - - - - - - - - - PEGA CMS3_k127_4821967_2 309807.SRU_1453 8.974e-05 52.0 2C6S2@1|root,2ZQXA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4821967_0 204669.Acid345_3200 6.321e-46 179.0 2AWXU@1|root,31NVG@2|Bacteria,3Y98N@57723|Acidobacteria,2JP54@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - CMS3_k127_4822567_7 991.IW20_06790 5.062e-08 56.0 2CCSR@1|root,32RSC@2|Bacteria,4NT8X@976|Bacteroidetes,1IKXG@117743|Flavobacteriia,2NWU7@237|Flavobacterium 976|Bacteroidetes S 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP CMS3_k127_4822567_0 1121875.KB907546_gene2622 0.0 1062.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,1HWYF@117743|Flavobacteriia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - Laminin_G_3,PSCyt1,PSCyt2,PSD1 CMS3_k127_4822567_2 760192.Halhy_0748 1.427e-163 529.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_4822567_1 1122179.KB890450_gene4581 7.043e-291 900.0 COG0033@1|root,COG0033@2|Bacteria,4P086@976|Bacteroidetes 976|Bacteroidetes G Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - - - - - - - - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS3_k127_4822567_6 1304865.JAGF01000001_gene965 8.473e-24 103.0 2EG8Z@1|root,33A0S@2|Bacteria,2I8BH@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - CMS3_k127_4822567_3 385682.AFSL01000046_gene537 2.741e-120 398.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,2FME1@200643|Bacteroidia,3XKFX@558415|Marinilabiliaceae 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_4822567_5 313628.LNTAR_07886 7.825e-54 191.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process yabJ_2 - - - - - - - - - - - Ribonuc_L-PSP CMS3_k127_4822567_4 760192.Halhy_2142 1.351e-99 329.0 COG1373@1|root,COG1373@2|Bacteria,4NG8U@976|Bacteroidetes,1ITM4@117747|Sphingobacteriia 976|Bacteroidetes S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_4825480_5 391596.PBAL39_06316 1.915e-13 70.0 COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1IQ15@117747|Sphingobacteriia 976|Bacteroidetes G Xylose isomerase - - 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 CMS3_k127_4825480_1 926690.KE386573_gene2108 1.382e-157 523.0 COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria 183963|Halobacteria E COG0531 Amino acid transporters - - - - - - - - - - - - AA_permease_2,AA_permease_C,Usp CMS3_k127_4825480_4 1288963.ADIS_1350 9.472e-49 184.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 CMS3_k127_4825480_0 118166.JH976537_gene2413 1.158e-245 775.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1G0Q0@1117|Cyanobacteria,1H8S9@1150|Oscillatoriales 1117|Cyanobacteria IQ Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II,adh_short,adh_short_C2 CMS3_k127_4825480_2 314256.OG2516_16479 6.092e-121 394.0 COG5564@1|root,COG5564@2|Bacteria,1MXTY@1224|Proteobacteria,2TSJ2@28211|Alphaproteobacteria 28211|Alphaproteobacteria T TIM-barrel enzyme, possibly a dioxygenase MA20_13935 - - - - - - - - - - - PEP_hydrolase CMS3_k127_4825480_3 467661.RKLH11_3573 5.028e-98 328.0 COG5441@1|root,COG5441@2|Bacteria,1MX45@1224|Proteobacteria,2TUHA@28211|Alphaproteobacteria,3ZGA3@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Uncharacterised protein family (UPF0261) - - - - - - - - - - - - ABC_tran,UPF0261 CMS3_k127_4825753_2 1120968.AUBX01000016_gene1706 1.015e-35 137.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,47JNX@768503|Cytophagia 976|Bacteroidetes S PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_4825753_3 1336803.PHEL49_1964 1.284e-15 81.0 COG0596@1|root,COG0596@2|Bacteria,4NIQH@976|Bacteroidetes,1IG08@117743|Flavobacteriia,3VXC9@52959|Polaribacter 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 CMS3_k127_4825753_0 1121904.ARBP01000018_gene2605 2.846e-237 747.0 COG1960@1|root,COG1960@2|Bacteria,4NEM4@976|Bacteroidetes,47MIF@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA dehydrogenase C-terminal like - - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N CMS3_k127_4825753_1 509635.N824_13805 5.061e-53 190.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 CMS3_k127_4826789_2 313606.M23134_08123 2.742e-33 143.0 COG4886@1|root,COG5635@1|root,COG4886@2|Bacteria,COG5635@2|Bacteria,4P0SG@976|Bacteroidetes 976|Bacteroidetes T Leucine-rich repeat (LRR) protein - - - - - - - - - - - - LRR_4 CMS3_k127_4826789_1 760192.Halhy_1122 6.97e-71 254.0 COG1262@1|root,COG1262@2|Bacteria,4NUFZ@976|Bacteroidetes 976|Bacteroidetes S PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - FGE-sulfatase CMS3_k127_4826789_0 1249997.JHZW01000003_gene3187 4.458e-128 420.0 COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,1I1KX@117743|Flavobacteriia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - Reg_prop CMS3_k127_4826789_3 1123037.AUDE01000027_gene2118 1.798e-28 117.0 2AZZY@1|root,31SA0@2|Bacteria,4NRJ3@976|Bacteroidetes,1I3N5@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4834963_2 1122176.KB903543_gene543 6.849e-131 449.0 COG1629@1|root,COG1629@2|Bacteria,4PN3N@976|Bacteroidetes,1IWAD@117747|Sphingobacteriia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec CMS3_k127_4834963_5 518766.Rmar_2471 7.69e-24 117.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion yeeJ - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,Big_3_3,HemolysinCabind,VWA_2 CMS3_k127_4834963_4 483216.BACEGG_01442 2.789e-90 306.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N CMS3_k127_4834963_1 483216.BACEGG_01441 6.02e-147 476.0 COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,2FUNV@200643|Bacteroidia 976|Bacteroidetes P Natural resistance-associated macrophage protein - - - - - - - - - - - - Nramp CMS3_k127_4834963_0 1121875.KB907550_gene788 0.0 1024.0 COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K02305,ko:K08738 ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00529,M00595 R00294,R10151 RC02794,RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.10,3.D.4.6 - - Cytochrom_C,HEAT_2 CMS3_k127_4834963_3 1048983.EL17_06380 5.161e-106 355.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y6D@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_4835706_1 760192.Halhy_2969 7.026e-27 116.0 COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1ITAS@117747|Sphingobacteriia 976|Bacteroidetes O Serine protease, subtilase family - - - - - - - - - - - - Peptidase_S8 CMS3_k127_4835706_0 153721.MYP_453 1.395e-56 226.0 COG2885@1|root,COG2885@2|Bacteria,4NEND@976|Bacteroidetes,47KG7@768503|Cytophagia 976|Bacteroidetes M Belongs to the ompA family - - - - - - - - - - - - OmpA,PD40 CMS3_k127_4835706_3 929556.Solca_0737 7.776e-14 86.0 COG3291@1|root,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1IR0W@117747|Sphingobacteriia 976|Bacteroidetes G Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - CHU_C,PKD,SASA CMS3_k127_4835706_4 1392498.JQLH01000001_gene547 9.293e-13 83.0 2EAVS@1|root,334X4@2|Bacteria,4NWJY@976|Bacteroidetes,1I6CS@117743|Flavobacteriia,2PGZF@252356|Maribacter 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4835706_2 926549.KI421517_gene1456 3.865e-15 81.0 COG1514@1|root,COG1514@2|Bacteria,4NZ5M@976|Bacteroidetes,47STA@768503|Cytophagia 976|Bacteroidetes J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase CMS3_k127_4840698_3 1121904.ARBP01000008_gene3412 2.063e-176 565.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,47MNP@768503|Cytophagia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_4840698_1 880070.Cycma_3424 0.0 1419.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47NEI@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4840698_2 1121904.ARBP01000008_gene3412 1.049e-268 839.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,47MNP@768503|Cytophagia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_4840698_0 880070.Cycma_3424 0.0 1422.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47NEI@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4844723_2 1168034.FH5T_05480 5.002e-76 268.0 COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,2FPG8@200643|Bacteroidia 976|Bacteroidetes S Tat pathway signal sequence domain protein - - - ko:K07079 - - - - ko00000 - - - Aldo_ket_red,Fer4_17 CMS3_k127_4844723_1 1121104.AQXH01000001_gene1688 8.194e-187 600.0 COG0457@1|root,COG0457@2|Bacteria,4NH87@976|Bacteroidetes,1IQZ9@117747|Sphingobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_4844723_4 1341155.FSS13T_17700 6.65e-23 106.0 2A9DX@1|root,30YJ9@2|Bacteria,4PCDN@976|Bacteroidetes,1IMZ0@117743|Flavobacteriia,2NWJ2@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4844723_0 761193.Runsl_1400 1.361e-256 798.0 COG2368@1|root,COG2368@2|Bacteria,4NKNT@976|Bacteroidetes 976|Bacteroidetes Q 4-hydroxybutyryl-CoA dehydratase abfD - 4.2.1.120,5.3.3.3 ko:K14534 ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200 M00374,M00375 R03031,R10782 RC01857,RC03277 ko00000,ko00001,ko00002,ko01000 - - - HpaB,HpaB_N CMS3_k127_4844723_3 1121459.AQXE01000009_gene534 1.427e-37 152.0 COG0438@1|root,COG0438@2|Bacteria,1NF2Z@1224|Proteobacteria,42V61@68525|delta/epsilon subdivisions,2WS5P@28221|Deltaproteobacteria,2M8T0@213115|Desulfovibrionales 28221|Deltaproteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 CMS3_k127_4851248_5 1121904.ARBP01000001_gene5704 4.275e-25 108.0 COG3064@1|root,COG3064@2|Bacteria,4NNZ9@976|Bacteroidetes,47RDR@768503|Cytophagia 976|Bacteroidetes M Membrane - - - - - - - - - - - - - CMS3_k127_4851248_3 1178482.BJB45_04520 2.032e-51 186.0 COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1XJUJ@135619|Oceanospirillales 135619|Oceanospirillales O Peptidyl-prolyl cis-trans isomerase slyD - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - FKBP_C CMS3_k127_4851248_1 153721.MYP_607 1.912e-194 615.0 COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,47M94@768503|Cytophagia 976|Bacteroidetes T PIN domain ybeZ_1 - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH CMS3_k127_4851248_6 65393.PCC7424_0465 1.269e-12 78.0 COG0515@1|root,COG0515@2|Bacteria 65393.PCC7424_0465|- KLT protein kinase activity - - - - - - - - - - - - - CMS3_k127_4851248_2 926549.KI421517_gene429 6.584e-100 335.0 COG1082@1|root,COG1082@2|Bacteria,4NIG9@976|Bacteroidetes,47NIT@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_4851248_0 388413.ALPR1_05670 1.059e-247 776.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia 976|Bacteroidetes Q PFAM D-aminoacylase, C-terminal region - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 CMS3_k127_4851248_4 641524.ADICYQ_3167 7.792e-26 107.0 COG2133@1|root,COG2133@2|Bacteria,4PNNH@976|Bacteroidetes,47KNR@768503|Cytophagia 976|Bacteroidetes G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_4855155_1 269798.CHU_3810 2.115e-112 374.0 COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,47M96@768503|Cytophagia 976|Bacteroidetes G Glycogen debranching enzyme - - - - - - - - - - - - GDE_C,GDE_N CMS3_k127_4855155_0 880070.Cycma_1835 1.705e-247 771.0 COG3119@1|root,COG3119@2|Bacteria,4NIP1@976|Bacteroidetes,47U7R@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase CMS3_k127_4855155_2 153721.MYP_1298 9.533e-10 63.0 COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,47NHH@768503|Cytophagia 976|Bacteroidetes QV Beta-lactamase - - - - - - - - - - - - Amidohydro_3,Beta-lactamase CMS3_k127_4856275_6 1185876.BN8_00335 1.784e-06 56.0 2E691@1|root,330X3@2|Bacteria,4NVM3@976|Bacteroidetes,47RUJ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4856275_0 1124780.ANNU01000008_gene2610 0.0 1640.0 COG1038@1|root,COG1038@2|Bacteria,4NFHU@976|Bacteroidetes,47N5S@768503|Cytophagia 976|Bacteroidetes C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second cfiB - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA CMS3_k127_4856275_5 269798.CHU_2709 1.729e-23 109.0 2C52N@1|root,2Z7U1@2|Bacteria,4NEZW@976|Bacteroidetes,47PC8@768503|Cytophagia 976|Bacteroidetes S Outer membrane protein beta-barrel domain porT - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_4856275_2 880070.Cycma_1822 1.908e-86 291.0 COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,47JXK@768503|Cytophagia 976|Bacteroidetes H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran CMS3_k127_4856275_3 1216967.L100_13160 1.397e-66 233.0 COG0218@1|root,COG0218@2|Bacteria,4NEA9@976|Bacteroidetes,1HXAB@117743|Flavobacteriia,34PJQ@308865|Elizabethkingia 976|Bacteroidetes D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 CMS3_k127_4856275_1 1250006.JHZZ01000001_gene2284 6.255e-126 413.0 COG0381@1|root,COG0381@2|Bacteria,4NGBD@976|Bacteroidetes,1HXDA@117743|Flavobacteriia,3VWNZ@52959|Polaribacter 976|Bacteroidetes M UDP-N-acetylglucosamine 2-epimerase wecB - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase_2 CMS3_k127_4856275_4 1227487.C474_07822 6.719e-37 145.0 COG0438@1|root,arCOG01410@2157|Archaea,2XV5R@28890|Euryarchaeota,23USK@183963|Halobacteria 183963|Halobacteria M COG0438 Glycosyltransferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_4856483_2 1124780.ANNU01000006_gene2877 6.577e-87 299.0 COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,47NI9@768503|Cytophagia 976|Bacteroidetes O Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling anmK - 2.7.1.170 ko:K09001 - - - - ko00000,ko01000 - - - AnmK CMS3_k127_4856483_3 1239962.C943_01365 3.097e-84 290.0 COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,47KFE@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function, DUF547 - - - - - - - - - - - - DUF547 CMS3_k127_4856483_1 1121904.ARBP01000001_gene5944 3.56e-163 528.0 COG0446@1|root,COG0446@2|Bacteria,4NET1@976|Bacteroidetes,47JW2@768503|Cytophagia 976|Bacteroidetes S Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2 CMS3_k127_4856483_0 1124780.ANNU01000008_gene2732 9.893e-200 638.0 COG0348@1|root,COG0348@2|Bacteria,4NHSX@976|Bacteroidetes,47KC5@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S dicluster domain yccM_2 - - - - - - - - - - - Fer4,Fer4_5,Fer4_7,Fer4_9 CMS3_k127_4856483_4 1168289.AJKI01000011_gene500 1.067e-64 223.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,2FSHE@200643|Bacteroidia,3XJKK@558415|Marinilabiliaceae 976|Bacteroidetes P Iron/manganese superoxide dismutases, alpha-hairpin domain sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N CMS3_k127_4859965_3 1356852.N008_12450 4.259e-35 154.0 COG1033@1|root,COG1033@2|Bacteria,4NKTD@976|Bacteroidetes,47UF5@768503|Cytophagia 976|Bacteroidetes S Patched family - - - ko:K07003 - - - - ko00000 - - - MMPL CMS3_k127_4859965_4 62977.ACIAD3674 1.333e-22 110.0 2BZ6D@1|root,2ZC6J@2|Bacteria,1RBC8@1224|Proteobacteria,1S3G8@1236|Gammaproteobacteria,3NMP7@468|Moraxellaceae 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_4859965_1 497964.CfE428DRAFT_1238 3.204e-163 526.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS3_k127_4859965_2 497964.CfE428DRAFT_1237 8.903e-162 520.0 COG1032@1|root,COG1032@2|Bacteria 2|Bacteria C radical SAM domain protein - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS3_k127_4859965_0 1121324.CLIT_2c02260 2.953e-192 608.0 COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia 186801|Clostridia C PFAM Radical SAM - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS3_k127_4860036_3 1279009.ADICEAN_03017 1.187e-52 193.0 COG0546@1|root,COG0546@2|Bacteria,4P3I1@976|Bacteroidetes 976|Bacteroidetes S HAD-hyrolase-like - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 CMS3_k127_4860036_1 1124780.ANNU01000036_gene8 1.632e-84 290.0 COG0382@1|root,COG0382@2|Bacteria,4NIRK@976|Bacteroidetes,47SWZ@768503|Cytophagia 976|Bacteroidetes H UbiA prenyltransferase family - - - - - - - - - - - - UbiA CMS3_k127_4860036_0 421072.IO89_17210 4.191e-173 553.0 COG0277@1|root,COG0277@2|Bacteria,4NGC5@976|Bacteroidetes,1HZMT@117743|Flavobacteriia,3HGQY@358033|Chryseobacterium 976|Bacteroidetes C FAD binding domain - - - - - - - - - - - - FAD_binding_4 CMS3_k127_4860036_2 1279009.ADICEAN_00257 5.077e-69 242.0 COG0300@1|root,COG0300@2|Bacteria,4NIGI@976|Bacteroidetes,47TQ2@768503|Cytophagia 976|Bacteroidetes S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short CMS3_k127_4860036_4 1267533.KB906740_gene251 7.599e-36 154.0 2DS1X@1|root,33E5S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4860036_5 1237149.C900_00032 9.545e-28 122.0 COG2353@1|root,COG2911@1|root,COG2353@2|Bacteria,COG2911@2|Bacteria,4PMEU@976|Bacteroidetes,47RH2@768503|Cytophagia 976|Bacteroidetes G Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - BNR_assoc_N,Laminin_G_3 CMS3_k127_4862638_1 1166018.FAES_0567 2.686e-94 313.0 COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,47JMK@768503|Cytophagia 976|Bacteroidetes E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CMS3_k127_4862638_0 929556.Solca_1911 7.347e-136 441.0 COG0836@1|root,COG0836@2|Bacteria,4NE1Y@976|Bacteroidetes,1INM4@117747|Sphingobacteriia 976|Bacteroidetes M mannose-1-phosphate guanylyltransferase manC - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CMS3_k127_4862638_2 886379.AEWI01000013_gene2197 3.232e-12 69.0 COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,2G2X9@200643|Bacteroidia,3XJH3@558415|Marinilabiliaceae 976|Bacteroidetes CO Domain of unknown function (DUF4369) - - - - - - - - - - - - AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8 CMS3_k127_4881319_3 1121373.KB903623_gene2323 2.435e-05 51.0 2A0PG@1|root,30NTS@2|Bacteria,4PB8I@976|Bacteroidetes,47VFB@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4881319_0 761193.Runsl_2267 1.064e-69 241.0 COG2010@1|root,COG2010@2|Bacteria,4NN91@976|Bacteroidetes,47PSM@768503|Cytophagia 976|Bacteroidetes C Haem-binding domain - - - - - - - - - - - - Haem_bd CMS3_k127_4881319_1 313606.M23134_05517 2.722e-37 148.0 COG4636@1|root,COG4636@2|Bacteria,4NWGC@976|Bacteroidetes,47S8U@768503|Cytophagia 976|Bacteroidetes S Putative restriction endonuclease - - - - - - - - - - - - Uma2 CMS3_k127_4881319_2 929703.KE386491_gene1080 3.748e-24 104.0 COG1028@1|root,COG1028@2|Bacteria,4NF64@976|Bacteroidetes,47MEC@768503|Cytophagia 976|Bacteroidetes IQ PFAM Short-chain dehydrogenase reductase SDR - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_4881873_0 83406.HDN1F_36100 2.05e-102 344.0 2CDI5@1|root,2Z7ZQ@2|Bacteria,1Q9TA@1224|Proteobacteria,1SKQ9@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_4881873_8 655815.ZPR_4526 1.208e-20 93.0 2DNM0@1|root,32Y1X@2|Bacteria,4NWJ4@976|Bacteroidetes,1I5HN@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4881873_4 641524.ADICYQ_0077 3.594e-44 164.0 COG1848@1|root,COG1848@2|Bacteria,4NNGQ@976|Bacteroidetes,47STD@768503|Cytophagia 976|Bacteroidetes S PIN domain - - - - - - - - - - - - PIN,PIN_3 CMS3_k127_4881873_6 1168034.FH5T_17650 1.954e-25 114.0 COG1595@1|root,COG1595@2|Bacteria,4NVR6@976|Bacteroidetes 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2 CMS3_k127_4881873_2 929703.KE386491_gene3289 7.063e-71 248.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,47KCE@768503|Cytophagia 976|Bacteroidetes T PFAM response regulator receiver rprY - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_4881873_3 1408473.JHXO01000001_gene2484 3.549e-64 236.0 COG0642@1|root,COG2205@2|Bacteria,4NEFW@976|Bacteroidetes,2FSEE@200643|Bacteroidia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain rprX - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_4881873_1 1297742.A176_04293 5.355e-74 263.0 COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,43CIK@68525|delta/epsilon subdivisions,2WQ8R@28221|Deltaproteobacteria,2Z1G2@29|Myxococcales 28221|Deltaproteobacteria K DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI CMS3_k127_4881873_9 1461693.ATO10_04607 1.909e-16 84.0 COG1017@1|root,COG1017@2|Bacteria,1QVJP@1224|Proteobacteria,2U5M6@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Belongs to the globin family MA20_17055 - 1.14.12.17 ko:K05916 ko05132,map05132 - - - ko00000,ko00001,ko01000 - - - Globin CMS3_k127_4881873_5 319795.Dgeo_0488 2.662e-33 137.0 COG2340@1|root,COG2340@2|Bacteria,1WKKZ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S protein with SCP PR1 domains - - - - - - - - - - - - Big_2,CAP CMS3_k127_4881873_7 1121285.AUFK01000010_gene1719 8.789e-21 98.0 COG3637@1|root,COG3637@2|Bacteria,4NRH8@976|Bacteroidetes,1I3J9@117743|Flavobacteriia,3ZQCW@59732|Chryseobacterium 976|Bacteroidetes M OmpW family - - - ko:K07275 - - - - ko00000 - - - OMP_b-brl CMS3_k127_4881873_10 1469557.JSWF01000014_gene2529 1.612e-13 73.0 COG0515@1|root,COG5295@1|root,COG0515@2|Bacteria,COG5295@2|Bacteria,4NV9S@976|Bacteroidetes,1I8F6@117743|Flavobacteriia 976|Bacteroidetes UW Hep Hag repeat protein - - - - - - - - - - - - DUF1566 CMS3_k127_4884645_0 880073.Calab_1325 4.693e-86 300.0 COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria 2|Bacteria E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 CMS3_k127_4884645_1 504487.JCM19302_1059 6.421e-06 59.0 COG3209@1|root,COG3209@2|Bacteria,4NRDA@976|Bacteroidetes,1I3N8@117743|Flavobacteriia 976|Bacteroidetes M COG3209 Rhs family protein - - - - - - - - - - - - - CMS3_k127_4885364_3 1121904.ARBP01000004_gene927 1.036e-46 173.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug CMS3_k127_4885364_0 760192.Halhy_1417 1.76e-157 507.0 COG3825@1|root,COG3825@2|Bacteria,4NING@976|Bacteroidetes 976|Bacteroidetes S VWA domain containing CoxE-like protein - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE CMS3_k127_4885364_2 760192.Halhy_5226 1.439e-81 281.0 COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1IP8N@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 CMS3_k127_4885364_6 306281.AJLK01000036_gene5775 2.08e-10 63.0 COG4636@1|root,COG4636@2|Bacteria,1G5GI@1117|Cyanobacteria 1117|Cyanobacteria S InterPro IPR008538 - - - - - - - - - - - - Uma2 CMS3_k127_4885364_4 761193.Runsl_2025 3.275e-44 166.0 COG0607@1|root,COG0607@2|Bacteria,4NQ61@976|Bacteroidetes,47Q3A@768503|Cytophagia 976|Bacteroidetes P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese CMS3_k127_4885364_1 1121286.AUMT01000019_gene1819 4.439e-96 319.0 COG0580@1|root,COG0580@2|Bacteria,4NEFK@976|Bacteroidetes,1HYTU@117743|Flavobacteriia,3ZNPT@59732|Chryseobacterium 976|Bacteroidetes U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP CMS3_k127_4885364_5 1239415.CM001837_gene2081 5.382e-14 78.0 2C0KY@1|root,34ACU@2|Bacteria,4P571@976|Bacteroidetes,1IA8U@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4885364_7 292563.Cyast_1140 9.203e-07 57.0 COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1G0II@1117|Cyanobacteria 1117|Cyanobacteria M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,TPR_1,TPR_16,TPR_2,TPR_8 CMS3_k127_4886625_0 1121904.ARBP01000029_gene2184 2.262e-318 991.0 COG4654@1|root,COG4654@2|Bacteria 2|Bacteria C Cytochrome c, class I - - - - - - - - - - - - F5_F8_type_C,PSCyt1,PSCyt2,PSD1 CMS3_k127_4887363_0 760192.Halhy_5351 1.173e-127 430.0 COG1807@1|root,COG1807@2|Bacteria,4NPS7@976|Bacteroidetes 976|Bacteroidetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - CMS3_k127_4895681_0 926562.Oweho_0625 3.731e-213 686.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes,1HY9Q@117743|Flavobacteriia 976|Bacteroidetes P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4896230_8 1237149.C900_03042 2.813e-33 131.0 COG1621@1|root,COG1621@2|Bacteria,4NEYI@976|Bacteroidetes,47KIP@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.80 ko:K03332 ko00051,map00051 - R00879 - ko00000,ko00001,ko01000 - - - Glyco_hydro_32C,Glyco_hydro_32N CMS3_k127_4896230_2 313603.FB2170_03315 6.655e-190 602.0 COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,1HY74@117743|Flavobacteriia,2PG58@252356|Maribacter 976|Bacteroidetes EGP Sugar (and other) transporter - - - - - - - - - - - - Sugar_tr CMS3_k127_4896230_0 946077.W5A_07110 1.262e-220 707.0 COG1073@1|root,COG1073@2|Bacteria,4NG6A@976|Bacteroidetes,1I062@117743|Flavobacteriia 976|Bacteroidetes S alpha beta - - - - - - - - - - - - AXE1,BAAT_C,Hydrolase_4 CMS3_k127_4896230_3 1249997.JHZW01000003_gene2392 1.788e-147 475.0 COG0079@1|root,COG0079@2|Bacteria,4NEW8@976|Bacteroidetes,1HXQE@117743|Flavobacteriia,2PI2Y@252356|Maribacter 976|Bacteroidetes E Aminotransferase class-V - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_4896230_6 1341181.FLJC2902T_25270 6.672e-81 276.0 COG2518@1|root,COG2518@2|Bacteria,4NMTP@976|Bacteroidetes,1I1EU@117743|Flavobacteriia,2NYPM@237|Flavobacterium 976|Bacteroidetes J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT CMS3_k127_4896230_1 1232410.KI421414_gene2815 1.423e-213 689.0 COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,43TQY@69541|Desulfuromonadales 28221|Deltaproteobacteria E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth CMS3_k127_4896230_5 984262.SGRA_3679 2.43e-96 338.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_4896230_7 984262.SGRA_3680 1.003e-53 195.0 COG1672@1|root,COG1672@2|Bacteria,4NR06@976|Bacteroidetes 976|Bacteroidetes L Leucine-rich repeat (LRR) protein - - - - - - - - - - - - AAA_16 CMS3_k127_4896230_9 760192.Halhy_1697 1.907e-28 128.0 COG1672@1|root,COG1672@2|Bacteria,4NR06@976|Bacteroidetes 976|Bacteroidetes L Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - CMS3_k127_4896230_10 264201.pc0038 2.587e-05 57.0 COG4886@1|root,COG4886@2|Bacteria,2JH6G@204428|Chlamydiae 204428|Chlamydiae S Leucine-rich repeats, outliers - - - - - - - - - - - - LRR_8 CMS3_k127_4896230_4 760192.Halhy_6026 6.358e-122 394.0 COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,1IRQX@117747|Sphingobacteriia 976|Bacteroidetes G Haloacid Dehalogenase Superfamily Class (subfamily) IIA - - - ko:K02566 - - - - ko00000 - - - Hydrolase_6,Hydrolase_like CMS3_k127_4905523_2 1313421.JHBV01000035_gene2498 1.645e-08 60.0 COG4995@1|root,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1IXZE@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_7 CMS3_k127_4905523_0 504472.Slin_2709 1.04e-13 76.0 COG1595@1|root,COG1595@2|Bacteria,4NP91@976|Bacteroidetes,47PTK@768503|Cytophagia 976|Bacteroidetes K DNA-templated transcription, initiation - - - - - - - - - - - - - CMS3_k127_4905523_1 1120968.AUBX01000002_gene1497 7.384e-11 72.0 COG0457@1|root,COG0457@2|Bacteria,4NQ3P@976|Bacteroidetes,47YJC@768503|Cytophagia 976|Bacteroidetes S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_6 CMS3_k127_4913600_1 1121904.ARBP01000004_gene886 3.102e-125 409.0 COG0204@1|root,COG0204@2|Bacteria,4NJDA@976|Bacteroidetes,47MU0@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - - CMS3_k127_4913600_0 1124780.ANNU01000006_gene2950 0.0 1249.0 COG0178@1|root,COG0178@2|Bacteria,4NFQU@976|Bacteroidetes,47K0C@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran CMS3_k127_4913600_2 1313301.AUGC01000001_gene1466 2.268e-09 61.0 COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes 976|Bacteroidetes M Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD_2 - - - - - - - - - - - SLT CMS3_k127_4913678_2 1123277.KB893208_gene2823 3.16e-38 143.0 COG0296@1|root,COG2382@1|root,COG0296@2|Bacteria,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,47MEB@768503|Cytophagia 976|Bacteroidetes P Putative esterase - - - ko:K07214 - - - - ko00000 - - - Esterase CMS3_k127_4913678_3 234267.Acid_2106 1.587e-12 71.0 COG2272@1|root,COG2272@2|Bacteria,3Y3ME@57723|Acidobacteria 57723|Acidobacteria I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase CMS3_k127_4913678_0 760192.Halhy_0722 1.512e-267 831.0 COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,1IREX@117747|Sphingobacteriia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 CMS3_k127_4913678_1 760192.Halhy_0721 7.428e-135 433.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes 976|Bacteroidetes P TonB-linked outer membrane protein, SusC RagA family - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_4922267_4 1048983.EL17_06380 1.944e-62 218.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y6D@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_4922267_1 1048983.EL17_06385 1.248e-170 553.0 COG1395@1|root,COG1395@2|Bacteria,4PMSD@976|Bacteroidetes,47Y95@768503|Cytophagia 976|Bacteroidetes K SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_4922267_0 1123057.P872_16125 2.665e-294 938.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47JJ5@768503|Cytophagia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_4922267_3 694427.Palpr_0239 2.511e-89 308.0 COG2273@1|root,COG2273@2|Bacteria,4NHP5@976|Bacteroidetes,2FP9D@200643|Bacteroidia,22XHU@171551|Porphyromonadaceae 976|Bacteroidetes G Glycoside Hydrolase - - - - - - - - - - - - BACON,Glyco_hydro_16 CMS3_k127_4922267_2 760192.Halhy_5815 1.561e-121 411.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_4923532_0 1188252.AJYK01000005_gene2988 3.385e-297 932.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,1RN2W@1236|Gammaproteobacteria,1XTQD@135623|Vibrionales 135623|Vibrionales E Glutamate synthase gltB - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase CMS3_k127_4923532_2 760192.Halhy_4849 4.278e-194 608.0 COG0174@1|root,COG0174@2|Bacteria,4NGG2@976|Bacteroidetes,1IQ8U@117747|Sphingobacteriia 976|Bacteroidetes E PFAM glutamine synthetase catalytic region glnII - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N CMS3_k127_4923532_1 1121904.ARBP01000001_gene5718 1.975e-195 619.0 COG0004@1|root,COG0004@2|Bacteria,4NDV2@976|Bacteroidetes,47N2A@768503|Cytophagia 976|Bacteroidetes P Ammonium Transporter Family - - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp CMS3_k127_4923532_4 1121904.ARBP01000001_gene5717 5.043e-113 376.0 28IEX@1|root,2Z8GX@2|Bacteria,4NGBY@976|Bacteroidetes,47NK3@768503|Cytophagia 976|Bacteroidetes S Putative beta-barrel porin-2, OmpL-like. bbp2 - - - - - - - - - - - - BBP2 CMS3_k127_4923532_7 504472.Slin_3242 1.15e-29 133.0 COG0823@1|root,COG0823@2|Bacteria,4NYDT@976|Bacteroidetes,47SZI@768503|Cytophagia 976|Bacteroidetes U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 CMS3_k127_4923532_3 1040989.AWZU01000028_gene3006 7.05e-187 600.0 COG3573@1|root,COG3573@2|Bacteria,1MVX8@1224|Proteobacteria,2TVKJ@28211|Alphaproteobacteria,3JSJV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S FAD binding domain MA20_22130 - - ko:K07077 - - - - ko00000 - - - FAD_binding_2 CMS3_k127_4923532_5 761193.Runsl_0274 1.9e-54 203.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4923532_6 207954.MED92_08326 6.776e-48 181.0 COG0596@1|root,COG0596@2|Bacteria,1QUVT@1224|Proteobacteria,1T22Q@1236|Gammaproteobacteria,1XJU7@135619|Oceanospirillales 135619|Oceanospirillales S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_6 CMS3_k127_4924301_4 929703.KE386491_gene3249 7.099e-41 156.0 COG1018@1|root,COG1018@2|Bacteria,4NF24@976|Bacteroidetes,47KY6@768503|Cytophagia 976|Bacteroidetes C PFAM 2Fe-2S iron-sulfur cluster binding domain dmpP - - ko:K02613 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FAD_binding_6,Fer2,NAD_binding_1 CMS3_k127_4924301_7 1408254.T458_23915 0.0001077 53.0 28IPT@1|root,2Z8PM@2|Bacteria,1U4RB@1239|Firmicutes,4IENT@91061|Bacilli,273WD@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CMS3_k127_4924301_8 113355.CM001775_gene3892 0.0002251 51.0 COG0300@1|root,COG0300@2|Bacteria,1G2JD@1117|Cyanobacteria 1117|Cyanobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short CMS3_k127_4924301_0 1279009.ADICEAN_01532 2.207e-230 724.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,47JRA@768503|Cytophagia 976|Bacteroidetes G Carbohydrate phosphorylase glgP - 2.4.1.1,2.4.1.8 ko:K00688,ko:K00691 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R01555,R02111 RC00049 ko00000,ko00001,ko01000 - GH65,GT35 - Phosphorylase CMS3_k127_4924301_1 1048983.EL17_15215 1.028e-74 268.0 COG0614@1|root,COG0614@2|Bacteria,4NH9F@976|Bacteroidetes,47MZX@768503|Cytophagia 976|Bacteroidetes P PFAM periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 CMS3_k127_4924301_3 926562.Oweho_2757 7.022e-58 213.0 COG1196@1|root,COG1196@2|Bacteria,4NTB2@976|Bacteroidetes 976|Bacteroidetes D nuclear chromosome segregation - - - - - - - - - - - - - CMS3_k127_4924301_6 756067.MicvaDRAFT_5014 4.046e-05 47.0 COG2202@1|root,COG3437@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1H88U@1150|Oscillatoriales 1117|Cyanobacteria T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Response_reg CMS3_k127_4924301_5 221288.JH992901_gene1991 3.619e-12 73.0 COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1G2MH@1117|Cyanobacteria,1JI8Z@1189|Stigonemataceae 1117|Cyanobacteria T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg CMS3_k127_4931119_4 1123248.KB893317_gene4390 1.04e-33 149.0 COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,1IRP7@117747|Sphingobacteriia 976|Bacteroidetes V Peptidase C39 - - - ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112 - - ABC_membrane,ABC_tran,Peptidase_C39 CMS3_k127_4931119_3 118168.MC7420_6518 3.423e-94 348.0 COG0823@1|root,COG1404@1|root,COG2931@1|root,COG0823@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales 1117|Cyanobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B CMS3_k127_4931119_0 313606.M23134_05244 2.694e-179 572.0 COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase family M20 M25 M40 - - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_4931119_1 1168034.FH5T_04745 5.753e-174 556.0 COG1160@1|root,COG1160@2|Bacteria,4NE2J@976|Bacteroidetes,2FN63@200643|Bacteroidia 976|Bacteroidetes S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 CMS3_k127_4931119_5 215803.DB30_6858 2.539e-07 60.0 COG3055@1|root,COG5563@1|root,COG3055@2|Bacteria,COG5563@2|Bacteria,1QE0Q@1224|Proteobacteria,4318S@68525|delta/epsilon subdivisions,2WX4P@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Glyoxal oxidase N-terminus - - - - - - - - - - - - DUF1929,Glyoxal_oxid_N,Kelch_1,Kelch_4 CMS3_k127_4931119_2 880071.Fleli_1739 3.178e-98 329.0 COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,47K35@768503|Cytophagia 976|Bacteroidetes S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 CMS3_k127_4938741_3 382464.ABSI01000016_gene740 2.568e-63 242.0 COG2982@1|root,COG4932@1|root,COG2982@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K13735 ko05100,map05100 - - - ko00000,ko00001 - - - AsmA_2,CHU_C,Cna_B,DUF11,Invasin_D3,PPC,Peptidase_M10_C,Reprolysin_4,SprB,VCBS CMS3_k127_4938741_5 1185876.BN8_06469 2.828e-31 142.0 COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47JM8@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - DUF3829,VWA,VWA_2 CMS3_k127_4938741_4 929556.Solca_2746 1.477e-43 164.0 COG2001@1|root,COG2001@2|Bacteria,4NM4X@976|Bacteroidetes,1IS84@117747|Sphingobacteriia 976|Bacteroidetes K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ CMS3_k127_4938741_2 1408473.JHXO01000001_gene2457 4.457e-98 329.0 COG0275@1|root,COG0275@2|Bacteria,4NFQB@976|Bacteroidetes,2FMPT@200643|Bacteroidia 976|Bacteroidetes J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 CMS3_k127_4938741_7 1120968.AUBX01000011_gene3214 0.0003671 48.0 2ADW0@1|root,33NUF@2|Bacteria,4NXHC@976|Bacteroidetes,47T6J@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4938741_1 1124780.ANNU01000024_gene3118 1.224e-144 483.0 COG0768@1|root,COG0768@2|Bacteria,4NERV@976|Bacteroidetes,47K6U@768503|Cytophagia 976|Bacteroidetes M Cell division protein FtsI penicillin-binding protein 2 ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PASTA,PBP_dimer,Transpeptidase CMS3_k127_4938741_0 1358423.N180_11935 1.965e-171 552.0 COG0769@1|root,COG0769@2|Bacteria,4NE9W@976|Bacteroidetes,1INW4@117747|Sphingobacteriia 976|Bacteroidetes M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS3_k127_4938741_6 746697.Aeqsu_1876 5.037e-12 67.0 COG0472@1|root,COG0472@2|Bacteria,4NE0T@976|Bacteroidetes,1HWY5@117743|Flavobacteriia 976|Bacteroidetes M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 CMS3_k127_4943196_5 1122179.KB890416_gene2645 9.307e-18 87.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - PSCyt1 CMS3_k127_4943196_7 313606.M23134_03839 3.333e-09 68.0 COG1404@1|root,COG3210@1|root,COG1404@2|Bacteria,COG3210@2|Bacteria,4NZFA@976|Bacteroidetes 2|Bacteria U cellulase activity - - - ko:K15125 ko05133,map05133 - - - ko00000,ko00001,ko00536 - - - Haemagg_act CMS3_k127_4943196_2 1168034.FH5T_08655 1.532e-93 314.0 COG0434@1|root,COG0434@2|Bacteria,4P0R6@976|Bacteroidetes 976|Bacteroidetes S BtpA family - - - ko:K06971 - - - - ko00000 - - - BtpA CMS3_k127_4943196_1 1121481.AUAS01000006_gene894 3.634e-105 349.0 COG0223@1|root,COG0223@2|Bacteria,4NE8U@976|Bacteroidetes,47JDP@768503|Cytophagia 976|Bacteroidetes J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N CMS3_k127_4943196_6 1453498.LG45_08615 1.549e-09 63.0 2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,1I3ZA@117743|Flavobacteriia,2NWSI@237|Flavobacterium 976|Bacteroidetes S diacylglyceryl transferase - - - - - - - - - - - - - CMS3_k127_4943196_4 761193.Runsl_0601 1.057e-45 168.0 COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,47QE4@768503|Cytophagia 976|Bacteroidetes J TIGRFAM endoribonuclease L-PSP yjgF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP CMS3_k127_4943196_0 1313301.AUGC01000001_gene1483 3.246e-159 510.0 COG0626@1|root,COG0626@2|Bacteria,4NH38@976|Bacteroidetes 976|Bacteroidetes E COGs COG0626 Cystathionine beta-lyase cystathionine gamma-synthase - - - - - - - - - - - - Cys_Met_Meta_PP CMS3_k127_4943196_3 1121904.ARBP01000001_gene5968 1.323e-67 231.0 COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,47PM4@768503|Cytophagia 976|Bacteroidetes G PFAM KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase CMS3_k127_4948511_2 643867.Ftrac_0306 3.873e-110 378.0 COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,47KF7@768503|Cytophagia 976|Bacteroidetes U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas CMS3_k127_4948511_0 1122176.KB903531_gene2991 2.826e-246 770.0 COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,1IP4J@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase CMS3_k127_4948511_7 643867.Ftrac_1489 4.003e-42 161.0 COG0671@1|root,COG0671@2|Bacteria,4NNVQ@976|Bacteroidetes,47RBP@768503|Cytophagia 976|Bacteroidetes I PFAM PAP2 superfamily ybjG GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 CMS3_k127_4948511_10 1408473.JHXO01000007_gene931 6.513e-25 113.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 CMS3_k127_4948511_9 1356852.N008_19395 4.214e-30 126.0 2E919@1|root,333AJ@2|Bacteria,4P65A@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4948511_11 1356852.N008_19390 1.144e-23 109.0 2EGU2@1|root,33AK8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_4948511_8 1121930.AQXG01000017_gene3138 2.018e-30 127.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_N CMS3_k127_4948511_5 1121930.AQXG01000017_gene3137 3.302e-89 300.0 COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,1IWMK@117747|Sphingobacteriia 976|Bacteroidetes M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like CMS3_k127_4948511_1 468059.AUHA01000007_gene2661 1.908e-120 399.0 COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,1IVEI@117747|Sphingobacteriia 976|Bacteroidetes M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_4948511_4 946077.W5A_06436 1.505e-95 327.0 COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,1HXJE@117743|Flavobacteriia 976|Bacteroidetes M ABC-type transport system involved in lipoprotein release permease component lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD CMS3_k127_4948511_3 1168034.FH5T_17075 1.715e-101 334.0 COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,2FRNC@200643|Bacteroidia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_4948511_6 1121904.ARBP01000002_gene6765 6.799e-66 234.0 2C2F5@1|root,32WND@2|Bacteria,4NNJR@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4950985_1 269798.CHU_0668 6.258e-33 140.0 COG3489@1|root,COG3489@2|Bacteria,4NFAT@976|Bacteroidetes,47NBA@768503|Cytophagia 976|Bacteroidetes S Imelysin - - - ko:K07338 - - - - ko00000 - - - Peptidase_M75 CMS3_k127_4950985_0 1237149.C900_02513 1.265e-55 209.0 28HNS@1|root,2Z7WY@2|Bacteria,4NDYC@976|Bacteroidetes,47RCV@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4856) - - - - - - - - - - - - DUF4856 CMS3_k127_4950985_2 679937.Bcop_0968 0.0004241 52.0 COG1388@1|root,COG1388@2|Bacteria,4NG96@976|Bacteroidetes,2FNR1@200643|Bacteroidia,4AKK3@815|Bacteroidaceae 976|Bacteroidetes M LysM domain lysM - - - - - - - - - - - ANF_receptor,LysM,Peripla_BP_6 CMS3_k127_4951422_1 553175.POREN0001_1211 2.308e-17 87.0 2BZ8H@1|root,32R4H@2|Bacteria,4NRUQ@976|Bacteroidetes,2FTBX@200643|Bacteroidia,22Y57@171551|Porphyromonadaceae 976|Bacteroidetes S Family of unknown function (DUF695) - - - - - - - - - - - - DUF695 CMS3_k127_4951422_2 647113.Metok_0281 2.468e-08 57.0 COG2361@1|root,arCOG05024@2157|Archaea,2Y0GK@28890|Euryarchaeota 28890|Euryarchaeota S Protein of unknown function DUF86 - - - ko:K07075 - - - - ko00000 - - - DUF86 CMS3_k127_4951422_0 1265503.KB905170_gene176 6.995e-108 389.0 COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q7NV@267889|Colwelliaceae 1236|Gammaproteobacteria T Two component regulator propeller - - - ko:K19694 - - - - ko00000,ko01001,ko02022 - - - 7TMR-DISM_7TM,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y,dCache_1 CMS3_k127_4954154_2 309807.SRU_2391 1.115e-181 574.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase CMS3_k127_4954154_4 388413.ALPR1_00680 3.711e-148 477.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - Cu_amine_oxidN1,Phytase-like CMS3_k127_4954154_1 388413.ALPR1_00675 6.79e-222 707.0 COG5276@1|root,COG5276@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Big_2,DUF1566,LVIVD,Pec_lyase_C,Pectinesterase CMS3_k127_4954154_5 1121007.AUML01000033_gene2793 2.845e-140 448.0 COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,1I7A4@117743|Flavobacteriia 976|Bacteroidetes S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase CMS3_k127_4954154_0 1121007.AUML01000033_gene2794 1.81e-227 713.0 COG0603@1|root,COG0603@2|Bacteria,4NM2T@976|Bacteroidetes,1I8FT@117743|Flavobacteriia 976|Bacteroidetes F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - - - - - - - - - - - CMS3_k127_4954154_3 983548.Krodi_0264 1.276e-181 574.0 COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,1I06G@117743|Flavobacteriia,37FQI@326319|Dokdonia 976|Bacteroidetes S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N CMS3_k127_4954154_6 1121875.KB907550_gene751 1.704e-25 106.0 COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1HZYM@117743|Flavobacteriia 976|Bacteroidetes E Pyridoxal-phosphate dependent enzyme - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - LeuA_dimer,PALP CMS3_k127_4958430_2 378806.STAUR_1557 6.886e-37 151.0 COG2220@1|root,COG2220@2|Bacteria 2|Bacteria S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - - - - - - - - - - Lactamase_B_3 CMS3_k127_4958430_0 760192.Halhy_1139 2.866e-272 863.0 COG1629@1|root,COG4771@2|Bacteria,4NJBC@976|Bacteroidetes,1J04Q@117747|Sphingobacteriia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug CMS3_k127_4958430_1 1288963.ADIS_1386 8.13e-161 515.0 28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_4966378_1 1123037.AUDE01000024_gene1628 3.969e-86 290.0 COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,1I052@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase class C and other penicillin binding - - - - - - - - - - - - Beta-lactamase CMS3_k127_4966378_0 1089547.KB913013_gene3092 1.171e-170 548.0 COG0277@1|root,COG0277@2|Bacteria,4NGC5@976|Bacteroidetes,47MIC@768503|Cytophagia 976|Bacteroidetes C D-arabinono-1,4-lactone oxidase - - 1.1.3.41 ko:K00594 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R07152,R11620 RC00108,RC00133 ko00000,ko00001,ko01000 - - - ALO,FAD_binding_4 CMS3_k127_4966684_2 1121481.AUAS01000002_gene3332 2.698e-31 127.0 COG1680@1|root,COG1680@2|Bacteria,4NEEP@976|Bacteroidetes,47KW2@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_4966684_1 268407.PWYN_02365 3.317e-109 372.0 COG1565@1|root,COG1565@2|Bacteria,1VRF3@1239|Firmicutes,4HUF6@91061|Bacilli,26QZJ@186822|Paenibacillaceae 91061|Bacilli S acr, cog1565 - - - - - - - - - - - - Methyltransf_28 CMS3_k127_4966684_0 1122179.KB890438_gene1533 1.242e-120 398.0 COG0574@1|root,COG0574@2|Bacteria,4NH4R@976|Bacteroidetes 976|Bacteroidetes G Pyruvate phosphate dikinase - - - - - - - - - - - - PPDK_N CMS3_k127_4984017_3 143224.JQMD01000002_gene1615 1.042e-163 520.0 COG3119@1|root,COG3119@2|Bacteria,4NFRB@976|Bacteroidetes,1HX8I@117743|Flavobacteriia 976|Bacteroidetes P Arylsulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C CMS3_k127_4984017_0 1121904.ARBP01000001_gene5503 4.31e-248 781.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,47NAD@768503|Cytophagia 976|Bacteroidetes G Glycosyl-hydrolase 97 C-terminal, oligomerisation - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - GH97_C,GH97_N,Glyco_hydro_97 CMS3_k127_4984017_4 497964.CfE428DRAFT_4910 2.753e-84 290.0 COG3173@1|root,COG3173@2|Bacteria 2|Bacteria S very-long-chain-acyl-CoA dehydrogenase activity - - - - - - - - - - - - APH CMS3_k127_4984017_1 1117647.M5M_16925 9.987e-178 567.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,1J4TX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N CMS3_k127_4984017_2 999419.HMPREF1077_00314 1.546e-176 568.0 COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,2FMY4@200643|Bacteroidia,22Z5B@171551|Porphyromonadaceae 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_4986328_0 643867.Ftrac_0481 1.458e-84 290.0 COG1984@1|root,COG1984@2|Bacteria,4NGIV@976|Bacteroidetes,47RJD@768503|Cytophagia 976|Bacteroidetes E PFAM Allophanate hydrolase subunit 2 - - - ko:K06350 - - - - ko00000 - - - CT_A_B CMS3_k127_4986328_1 1313421.JHBV01000142_gene1109 1.426e-62 222.0 COG2049@1|root,COG2049@2|Bacteria,4NMNT@976|Bacteroidetes,1ISIZ@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D CMS3_k127_4986328_2 1230342.CTM_11253 3.844e-08 55.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,36ERA@31979|Clostridiaceae 186801|Clostridia S Belongs to the UPF0271 (lamB) family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF CMS3_k127_4987004_6 1191523.MROS_0344 3.355e-31 126.0 COG0719@1|root,COG0719@2|Bacteria 2|Bacteria O iron-sulfur cluster assembly sufB GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - ko:K07033,ko:K09014 - - - - ko00000 - - iAPECO1_1312.APECO1_760,iECH74115_1262.ECH74115_2397,iECSF_1327.ECSF_1543,iECSP_1301.ECSP_2250,iUTI89_1310.UTI89_C1875,ic_1306.c2078 UPF0051 CMS3_k127_4987004_3 550540.Fbal_0374 3.301e-63 223.0 COG0637@1|root,COG0637@2|Bacteria,1NF90@1224|Proteobacteria,1RNP8@1236|Gammaproteobacteria 1236|Gammaproteobacteria S HAD-superfamily hydrolase subfamily IA, variant 3 yniC GO:0000287,GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050084,GO:0050286,GO:0050308,GO:0050309 3.1.3.23,5.4.2.6 ko:K01838,ko:K19270 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 CMS3_k127_4987004_5 1008457.BAEX01000055_gene625 2.213e-52 194.0 COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,47HIW@76831|Myroides 976|Bacteroidetes O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ppiA - 5.2.1.8 ko:K01802,ko:K03767,ko:K03772 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - FKBP_C,Pro_isomerase CMS3_k127_4987004_4 762903.Pedsa_2900 3.975e-60 221.0 COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,1IQI1@117747|Sphingobacteriia 976|Bacteroidetes T PFAM Signal transduction histidine kinase, internal region - - - - - - - - - - - - His_kinase CMS3_k127_4987004_2 485918.Cpin_1844 2.628e-67 237.0 COG3279@1|root,COG3279@2|Bacteria,4NIXU@976|Bacteroidetes,1IRCD@117747|Sphingobacteriia 976|Bacteroidetes T Two component transcriptional regulator, LytTR family - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_4987004_0 1124780.ANNU01000078_gene757 5.151e-298 934.0 COG1506@1|root,COG1506@2|Bacteria,4NE60@976|Bacteroidetes,47JEM@768503|Cytophagia 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_4987004_1 929703.KE386491_gene479 8.03e-72 250.0 COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,47K5B@768503|Cytophagia 976|Bacteroidetes H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase CMS3_k127_4987004_7 1122176.KB903538_gene1533 0.0004539 51.0 COG0457@1|root,COG0457@2|Bacteria 1122176.KB903538_gene1533|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - CMS3_k127_4991364_4 1121904.ARBP01000018_gene2613 8.199e-78 272.0 COG0008@1|root,COG0008@2|Bacteria,4NP0Y@976|Bacteroidetes,47Q0Q@768503|Cytophagia 976|Bacteroidetes J Belongs to the class-I aminoacyl-tRNA synthetase family - - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c CMS3_k127_4991364_2 1168034.FH5T_01475 4.043e-109 361.0 COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia 976|Bacteroidetes I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 CMS3_k127_4991364_3 1279009.ADICEAN_01940 2.377e-87 295.0 COG1028@1|root,COG1028@2|Bacteria,4NMH8@976|Bacteroidetes,47P21@768503|Cytophagia 976|Bacteroidetes IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CMS3_k127_4991364_6 313606.M23134_08243 3.105e-39 154.0 COG0344@1|root,COG0344@2|Bacteria,4NMU3@976|Bacteroidetes,47MPA@768503|Cytophagia 976|Bacteroidetes I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf CMS3_k127_4991364_0 1121930.AQXG01000003_gene2469 4.503e-189 599.0 COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1IR4T@117747|Sphingobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa CMS3_k127_4991364_7 1121104.AQXH01000001_gene999 4.468e-34 137.0 COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes 976|Bacteroidetes K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB CMS3_k127_4991364_1 1124780.ANNU01000018_gene1655 5.564e-123 401.0 COG0473@1|root,COG0473@2|Bacteria,4NGUA@976|Bacteroidetes,47KD2@768503|Cytophagia 976|Bacteroidetes CE Isocitrate dehydrogenase - - 1.1.1.41,1.1.1.85 ko:K00030,ko:K00052 ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00432,M00535 R00709,R00994,R04426,R10052 RC00084,RC00114,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS3_k127_5012724_1 504472.Slin_2383 1.208e-70 248.0 COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,47M2T@768503|Cytophagia 976|Bacteroidetes LU TIGRFAM DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A,HHH_5 CMS3_k127_5012724_3 1313301.AUGC01000006_gene133 1.672e-07 61.0 2E9XE@1|root,33436@2|Bacteria,4NV30@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5012724_0 1279009.ADICEAN_04130 8.185e-130 443.0 COG1033@1|root,COG1033@2|Bacteria,4NE0M@976|Bacteroidetes,47JQA@768503|Cytophagia 976|Bacteroidetes S COGs COG1033 exporter of the RND superfamily protein - - - ko:K07003 - - - - ko00000 - - - MMPL CMS3_k127_5012724_2 273121.WS1161 1.575e-16 83.0 COG4872@1|root,COG4872@2|Bacteria,1N2XF@1224|Proteobacteria,42QEG@68525|delta/epsilon subdivisions,2YNTN@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Predicted membrane protein (DUF2157) - - - - - - - - - - - - DUF2157 CMS3_k127_5012785_3 1121904.ARBP01000033_gene3216 2.451e-84 299.0 COG5002@1|root,COG5002@2|Bacteria,4PKBV@976|Bacteroidetes,47MII@768503|Cytophagia 976|Bacteroidetes T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS3_k127_5012785_2 313596.RB2501_15979 4.686e-85 287.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,1HYAN@117743|Flavobacteriia 976|Bacteroidetes T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain rprY - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_5012785_1 1519464.HY22_05730 2.708e-89 317.0 COG3975@1|root,COG3975@2|Bacteria,1FEP2@1090|Chlorobi 1090|Chlorobi S M61 glycyl aminopeptidase - - - - - - - - - - - - PDZ_2,Peptidase_M61 CMS3_k127_5012785_4 153721.MYP_278 1.659e-66 233.0 COG1143@1|root,COG1143@2|Bacteria,4NGWR@976|Bacteroidetes,47MDD@768503|Cytophagia 976|Bacteroidetes C 4Fe-4S ferredoxin iron-sulfur binding domain protein ndhI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 CMS3_k127_5012785_0 1121481.AUAS01000014_gene2453 1.586e-107 355.0 COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,47JF2@768503|Cytophagia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh CMS3_k127_5013152_2 1237149.C900_03168 2.412e-21 96.0 COG4270@1|root,COG4270@2|Bacteria,4NVXH@976|Bacteroidetes,47WJK@768503|Cytophagia 976|Bacteroidetes S Membrane - - - - - - - - - - - - DoxX CMS3_k127_5013152_0 1313421.JHBV01000015_gene5768 1.538e-259 817.0 COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia 976|Bacteroidetes O COG1331 Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH CMS3_k127_5013152_1 153721.MYP_2617 3.125e-225 723.0 COG1629@1|root,COG4771@2|Bacteria,4NFZY@976|Bacteroidetes,47M16@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - ko:K16087 - - - - ko00000,ko02000 1.B.14.2 - - Plug,TonB_dep_Rec CMS3_k127_5017273_0 1237149.C900_05460 1.198e-131 425.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47NKU@768503|Cytophagia 976|Bacteroidetes T Sigma-54 interaction domain - - - - - - - - - - - - Response_reg,Sigma54_activat CMS3_k127_5017273_1 1408433.JHXV01000009_gene1251 8.043e-105 369.0 COG0642@1|root,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,1HXAX@117743|Flavobacteriia,2PBD9@246874|Cryomorphaceae 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg CMS3_k127_5017273_2 1116472.MGMO_204c00070 1.751e-76 260.0 COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,1RZTV@1236|Gammaproteobacteria 1236|Gammaproteobacteria M epimerase dehydratase - - - - - - - - - - - - Epimerase CMS3_k127_5022349_2 323261.Noc_0932 4.671e-16 80.0 2C4KB@1|root,32YM4@2|Bacteria,1N74A@1224|Proteobacteria,1SH6J@1236|Gammaproteobacteria,1X1WN@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - CMS3_k127_5022349_0 331113.SNE_A15500 1.452e-113 390.0 COG1132@1|root,COG1132@2|Bacteria,2JFIQ@204428|Chlamydiae 204428|Chlamydiae V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CMS3_k127_5022349_3 530564.Psta_3762 4.01e-09 62.0 2AYUZ@1|root,31R0F@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_5022349_1 1007103.AFHW01000025_gene361 9.73e-74 265.0 COG1555@1|root,COG1555@2|Bacteria,1VTMY@1239|Firmicutes 1239|Firmicutes L COG1555 DNA uptake protein and related DNA-binding proteins - - - - - - - - - - - - HHH_3 CMS3_k127_5032653_0 1122605.KB893631_gene3911 4.454e-216 674.0 COG0719@1|root,COG0719@2|Bacteria,4NFXH@976|Bacteroidetes,1IP4R@117747|Sphingobacteriia 976|Bacteroidetes O FeS assembly protein SufB sufB - - ko:K09014 - - - - ko00000 - - - UPF0051 CMS3_k127_5032653_2 1313301.AUGC01000021_gene1226 7.829e-124 400.0 COG0396@1|root,COG0396@2|Bacteria,4NEMY@976|Bacteroidetes 976|Bacteroidetes O Fe-S assembly ATPase, SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran CMS3_k127_5032653_3 1237149.C900_05661 4.32e-112 376.0 COG0719@1|root,COG0719@2|Bacteria,4NFPG@976|Bacteroidetes,47K0R@768503|Cytophagia 976|Bacteroidetes O TIGRFAM FeS assembly protein SufD sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 CMS3_k127_5032653_1 926562.Oweho_2651 2.411e-170 543.0 COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia,2PAEG@246874|Cryomorphaceae 976|Bacteroidetes E Cys/Met metabolism PLP-dependent enzyme sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 CMS3_k127_5032653_4 1111730.ATTM01000003_gene706 1.567e-10 65.0 COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,2NWWT@237|Flavobacterium 976|Bacteroidetes S FeS assembly SUF system protein yitW - - - - - - - - - - - FeS_assembly_P CMS3_k127_5035611_8 929556.Solca_2795 2.929e-13 79.0 2DC2E@1|root,2ZCMH@2|Bacteria,4NN02@976|Bacteroidetes,1IRWH@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_5035611_10 1094466.KQS_13730 0.0004688 51.0 COG3266@1|root,COG3637@1|root,COG3266@2|Bacteria,COG3637@2|Bacteria,4NH1U@976|Bacteroidetes,1HX0D@117743|Flavobacteriia,2NUNC@237|Flavobacterium 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl_2 CMS3_k127_5035611_4 1349822.NSB1T_02110 3.13e-52 190.0 COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,2FSRW@200643|Bacteroidia,22Y21@171551|Porphyromonadaceae 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5035611_1 313606.M23134_03463 1.491e-99 331.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,47M4X@768503|Cytophagia 976|Bacteroidetes J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS CMS3_k127_5035611_0 1346330.M472_19480 1.399e-109 361.0 COG1092@1|root,COG1092@2|Bacteria,4NGJX@976|Bacteroidetes,1IRFX@117747|Sphingobacteriia 976|Bacteroidetes J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM CMS3_k127_5035611_2 1454007.JAUG01000076_gene1353 8.397e-57 215.0 COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1IPB7@117747|Sphingobacteriia 976|Bacteroidetes I membrane - - - - - - - - - - - - - CMS3_k127_5035611_6 926559.JoomaDRAFT_0927 1.102e-44 171.0 COG1521@1|root,COG1521@2|Bacteria,4NE9E@976|Bacteroidetes,1I1AK@117743|Flavobacteriia 976|Bacteroidetes H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase CMS3_k127_5035611_3 1124780.ANNU01000054_gene3527 4.927e-55 201.0 COG0340@1|root,COG0340@2|Bacteria,4NHCH@976|Bacteroidetes,47MUP@768503|Cytophagia 976|Bacteroidetes H PFAM Biotin lipoate A B protein ligase birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_LplA_LipB CMS3_k127_5035611_7 1239962.C943_00248 4.629e-28 117.0 COG0799@1|root,COG0799@2|Bacteria,4NSKK@976|Bacteroidetes,47Q9C@768503|Cytophagia 976|Bacteroidetes S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS CMS3_k127_5035611_9 1121904.ARBP01000005_gene4457 2.461e-08 63.0 COG4886@1|root,COG4886@2|Bacteria,4NHJ3@976|Bacteroidetes,47NN3@768503|Cytophagia 976|Bacteroidetes S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - LRR_4 CMS3_k127_5035611_5 553174.HMPREF0659_A6179 1.078e-49 181.0 COG0514@1|root,COG0514@2|Bacteria,4NEB4@976|Bacteroidetes,2FMBR@200643|Bacteroidia 976|Bacteroidetes L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind CMS3_k127_5049690_2 1380384.JADN01000008_gene1302 1.271e-75 262.0 2DBMF@1|root,2Z9YG@2|Bacteria,4NPRW@976|Bacteroidetes,1I1PP@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5049690_1 1121904.ARBP01000021_gene3620 6.675e-216 678.0 COG4948@1|root,COG4948@2|Bacteria,4NIIJ@976|Bacteroidetes,47K75@768503|Cytophagia 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_5049690_0 1123277.KB893176_gene3707 0.0 1055.0 COG2173@1|root,COG2173@2|Bacteria 2|Bacteria M zinc D-Ala-D-Ala carboxypeptidase activity - - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15,SH3_3,SH3_4,VanY CMS3_k127_5050365_0 1463855.JOHV01000007_gene5070 1.18e-34 145.0 COG2133@1|root,COG2133@2|Bacteria,2IB3Z@201174|Actinobacteria 201174|Actinobacteria G pyrroloquinoline quinone binding - - - - - - - - - - - - - CMS3_k127_5050365_1 497964.CfE428DRAFT_2702 5.846e-22 100.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity - - - - - - - - - - - - Cyclase CMS3_k127_5050818_10 743722.Sph21_2377 9.527e-05 48.0 2AFDM@1|root,315DF@2|Bacteria,4NQ5K@976|Bacteroidetes,1ISUS@117747|Sphingobacteriia 976|Bacteroidetes S rod shape-determining protein MreD mreD - - - - - - - - - - - - CMS3_k127_5050818_5 1121101.HMPREF1532_04133 1.25e-35 147.0 COG1792@1|root,COG1792@2|Bacteria,4NF14@976|Bacteroidetes,2FMWS@200643|Bacteroidia,4ANWS@815|Bacteroidaceae 976|Bacteroidetes M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC CMS3_k127_5050818_1 1237149.C900_01026 2.1e-166 528.0 COG1077@1|root,COG1077@2|Bacteria,4NETQ@976|Bacteroidetes,47JQ4@768503|Cytophagia 976|Bacteroidetes D TIGRFAM cell shape determining protein, MreB Mrl family mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl CMS3_k127_5050818_0 1313301.AUGC01000008_gene400 2.598e-182 583.0 COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes 976|Bacteroidetes F bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS CMS3_k127_5050818_3 762903.Pedsa_2160 3.13e-52 190.0 COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1IQHJ@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N CMS3_k127_5050818_8 880070.Cycma_4777 1.322e-25 117.0 COG0810@1|root,COG0810@2|Bacteria 2|Bacteria M energy transducer activity - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - CarboxypepD_reg,MORN_2,Plug,TonB_C CMS3_k127_5050818_9 1216967.L100_06075 6.939e-10 69.0 COG0810@1|root,COG0810@2|Bacteria,4NI38@976|Bacteroidetes,1I0AA@117743|Flavobacteriia,34R5C@308865|Elizabethkingia 976|Bacteroidetes M Gram-negative bacterial TonB protein C-terminal tonB - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_5050818_7 1227739.Hsw_0356 7.601e-27 117.0 COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,47Q1Y@768503|Cytophagia 976|Bacteroidetes U PFAM Biopolymer transport protein ExbD TolR exbD2 - - - - - - - - - - - ExbD CMS3_k127_5050818_6 153721.MYP_4033 1.703e-29 125.0 COG0848@1|root,COG0848@2|Bacteria,4NMQ8@976|Bacteroidetes,47Q1Y@768503|Cytophagia 976|Bacteroidetes U PFAM Biopolymer transport protein ExbD TolR exbD2 - - - - - - - - - - - ExbD CMS3_k127_5050818_4 761193.Runsl_1443 1.918e-36 146.0 COG0848@1|root,COG0848@2|Bacteria,4NMT4@976|Bacteroidetes,47NTX@768503|Cytophagia 976|Bacteroidetes U PFAM Biopolymer transport protein ExbD TolR exbD1 - - - - - - - - - - - ExbD CMS3_k127_5050818_2 760192.Halhy_0330 5.778e-70 248.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,1INP5@117747|Sphingobacteriia 976|Bacteroidetes U PFAM MotA TolQ ExbB proton channel exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB CMS3_k127_5063085_1 1123277.KB893179_gene3208 6.58e-91 312.0 COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47MFI@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_D23 CMS3_k127_5063085_0 269798.CHU_2513 4.018e-225 718.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47ME1@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS3_k127_5069151_3 388413.ALPR1_01250 1.852e-64 228.0 COG0668@1|root,COG0668@2|Bacteria,4NF1H@976|Bacteroidetes,47QUJ@768503|Cytophagia 976|Bacteroidetes M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,TM_helix CMS3_k127_5069151_2 1223410.KN050846_gene1076 5.171e-92 333.0 COG0457@1|root,COG0457@2|Bacteria,4NJ7M@976|Bacteroidetes,1I0QV@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_6,TPR_8 CMS3_k127_5069151_0 357808.RoseRS_2067 1.195e-217 703.0 COG1620@1|root,COG1620@2|Bacteria,2G6VR@200795|Chloroflexi 200795|Chloroflexi C L-lactate permease - - - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm CMS3_k127_5069151_1 1191523.MROS_1588 9.639e-136 441.0 COG0738@1|root,COG0738@2|Bacteria 2|Bacteria G Major facilitator superfamily fucP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 CMS3_k127_5070244_1 1122176.KB903576_gene5032 2.355e-113 406.0 COG2319@1|root,COG4995@1|root,COG2319@2|Bacteria,COG4995@2|Bacteria,4P49H@976|Bacteroidetes 976|Bacteroidetes H WD40 repeats - - - - - - - - - - - - CHAT CMS3_k127_5070244_2 1121904.ARBP01000042_gene4930 2.214e-07 57.0 2BVIX@1|root,32QWY@2|Bacteria,4NRQE@976|Bacteroidetes,47T45@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5070244_0 388413.ALPR1_01415 6.193e-278 862.0 COG2303@1|root,COG2303@2|Bacteria,4NI42@976|Bacteroidetes,47MET@768503|Cytophagia 976|Bacteroidetes E Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N CMS3_k127_5072105_3 1185876.BN8_06448 1.226e-43 164.0 COG1082@1|root,COG1082@2|Bacteria,4NEUS@976|Bacteroidetes,47NHQ@768503|Cytophagia 976|Bacteroidetes G PFAM Xylose isomerase - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_5072105_2 1123277.KB893206_gene3285 8.313e-82 280.0 COG3257@1|root,COG3257@2|Bacteria,4NKCS@976|Bacteroidetes,47M25@768503|Cytophagia 976|Bacteroidetes L Cupin domain - - 3.5.3.26 ko:K14977 ko00230,ko01120,map00230,map01120 - R05554 RC01419 ko00000,ko00001,ko01000 - - - AraC_binding,Cupin_2 CMS3_k127_5072105_0 1124780.ANNU01000006_gene2786 2.131e-302 942.0 COG3661@1|root,COG3661@2|Bacteria,4NHE2@976|Bacteroidetes,47M6Y@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 67 family aguA - 3.2.1.139 ko:K01235 - - - - ko00000,ko01000 - - - Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N CMS3_k127_5072105_1 700598.Niako_0754 7.59e-154 494.0 COG1312@1|root,COG1312@2|Bacteria,4NFA5@976|Bacteroidetes,1IW5I@117747|Sphingobacteriia 976|Bacteroidetes G Catalyzes the dehydration of D-mannonate uxuA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - UxuA CMS3_k127_5074070_2 1120965.AUBV01000008_gene2125 4.239e-40 151.0 COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,47KPR@768503|Cytophagia 976|Bacteroidetes EH Reduction of activated sulfate into sulfite cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct CMS3_k127_5074070_1 1124780.ANNU01000019_gene1782 2.694e-181 575.0 COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,47KC8@768503|Cytophagia 976|Bacteroidetes E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ - - ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01288 RC00020,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_5074070_0 929556.Solca_2281 3.47e-266 834.0 COG0155@1|root,COG1895@1|root,COG0155@2|Bacteria,COG1895@2|Bacteria,4NENW@976|Bacteroidetes,1INY4@117747|Sphingobacteriia 976|Bacteroidetes C Nitrite and sulphite reductase 4Fe-4S sir - 1.8.7.1 ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00859,R03600 RC00065 ko00000,ko00001,ko00002,ko01000 - - - HEPN,NIR_SIR,NIR_SIR_ferr CMS3_k127_5087373_0 1122176.KB903576_gene5032 1.123e-36 161.0 COG2319@1|root,COG4995@1|root,COG2319@2|Bacteria,COG4995@2|Bacteria,4P49H@976|Bacteroidetes 976|Bacteroidetes H WD40 repeats - - - - - - - - - - - - CHAT CMS3_k127_5087373_3 13616.ENSMODP00000013304 6.892e-22 111.0 COG4886@1|root,KOG0619@2759|Eukaryota,38E6Q@33154|Opisthokonta,3BE4G@33208|Metazoa,3D0J2@33213|Bilateria,483Q5@7711|Chordata,493SB@7742|Vertebrata,3JE2J@40674|Mammalia,4K944@9263|Metatheria 33208|Metazoa S Leucine-rich repeats and death domain containing 1 LRRD1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007154,GO:0007163,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0016323,GO:0023052,GO:0030011,GO:0035088,GO:0035090,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045197,GO:0045199,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0061245,GO:0065007,GO:0071944,GO:0098590 - - - - - - - - - - LRR_1,LRR_8 CMS3_k127_5087373_2 1469607.KK073768_gene3131 3.047e-27 129.0 COG0745@1|root,COG4928@1|root,COG0745@2|Bacteria,COG4928@2|Bacteria,1G1HK@1117|Cyanobacteria,1HKA8@1161|Nostocales 1117|Cyanobacteria T PFAM KAP family P-loop domain - - - - - - - - - - - - AAA_16 CMS3_k127_5087373_1 118168.MC7420_1469 8.882e-30 124.0 COG3825@1|root,COG3825@2|Bacteria,1G1TM@1117|Cyanobacteria,1HBDN@1150|Oscillatoriales 1117|Cyanobacteria S protein conserved in bacteria - - - ko:K09989 - - - - ko00000 - - - VWA_CoxE CMS3_k127_5091992_1 1089547.KB913013_gene575 1.644e-46 174.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug CMS3_k127_5091992_0 929562.Emtol_4087 4.983e-130 421.0 COG0714@1|root,COG0714@2|Bacteria,4NIHM@976|Bacteroidetes,47P4K@768503|Cytophagia 976|Bacteroidetes O AAA domain (dynein-related subfamily) - - - - - - - - - - - - AAA,AAA_5 CMS3_k127_5105842_1 1122176.KB903544_gene784 1.512e-70 246.0 COG0714@1|root,COG0714@2|Bacteria,4NPWR@976|Bacteroidetes,1IXGZ@117747|Sphingobacteriia 976|Bacteroidetes S SPTR ATPase associated with various cellular activities AAA_5 - - - - - - - - - - - - AAA CMS3_k127_5105842_2 1122176.KB903544_gene785 1.392e-53 218.0 COG1262@1|root,COG3291@1|root,COG3825@1|root,COG1262@2|Bacteria,COG3291@2|Bacteria,COG3825@2|Bacteria,4NFR2@976|Bacteroidetes,1J19D@117747|Sphingobacteriia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,Mfa_like_1 CMS3_k127_5105842_0 1185876.BN8_06216 3.905e-149 477.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia 976|Bacteroidetes EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 CMS3_k127_510822_5 153721.MYP_532 6.791e-62 222.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,47JBK@768503|Cytophagia 976|Bacteroidetes S Zn-ribbon protein, possibly nucleic acid-binding - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 CMS3_k127_510822_4 760192.Halhy_4009 7.636e-74 256.0 COG0327@1|root,COG0327@2|Bacteria,4NF51@976|Bacteroidetes 976|Bacteroidetes S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO - - - - - - - - - - - NIF3 CMS3_k127_510822_0 1237149.C900_01780 3.252e-259 830.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,47KGB@768503|Cytophagia 976|Bacteroidetes J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N CMS3_k127_510822_1 926549.KI421517_gene1846 5.748e-162 520.0 COG0195@1|root,COG0195@2|Bacteria,4NFGA@976|Bacteroidetes,47KFI@768503|Cytophagia 976|Bacteroidetes K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 CMS3_k127_510822_6 485917.Phep_0139 2.226e-24 109.0 COG0779@1|root,COG0779@2|Bacteria,4NQ32@976|Bacteroidetes,1IUA9@117747|Sphingobacteriia 976|Bacteroidetes S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C CMS3_k127_510822_2 880073.Calab_0401 1.175e-111 377.0 COG0534@1|root,COG0534@2|Bacteria,2NR3B@2323|unclassified Bacteria 2|Bacteria V Na -driven multidrug efflux pump norM - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE CMS3_k127_510822_3 760192.Halhy_4721 2.662e-91 323.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NVRP@976|Bacteroidetes 976|Bacteroidetes E Carboxypeptidase - - - - - - - - - - - - - CMS3_k127_5110472_12 1123355.JHYO01000031_gene1566 2.219e-11 76.0 COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,2UK9W@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - - CMS3_k127_5110472_0 1189612.A33Q_3003 5.561e-292 906.0 COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia 976|Bacteroidetes O PFAM Carbamoyltransferase - - - ko:K00612 - - - - ko00000,ko01000 - - - Carbam_trans_C,Carbam_trans_N CMS3_k127_5110472_11 880071.Fleli_3929 2.255e-16 79.0 2EGPU@1|root,33AFZ@2|Bacteria,4NXYH@976|Bacteroidetes,47S90@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5110472_9 1189612.A33Q_3000 1.525e-29 122.0 2E93X@1|root,333CT@2|Bacteria,4PPZQ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5110472_5 1341155.FSS13T_21560 9.458e-82 286.0 COG0535@1|root,COG0535@2|Bacteria,4NQ4R@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S single cluster domain - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,SPASM CMS3_k127_5110472_3 1122179.KB890422_gene2260 4.188e-117 396.0 COG4412@1|root,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - - - - - - - - - - - MAM,Peptidase_M6 CMS3_k127_5110472_13 797304.Natgr_3357 0.0009819 49.0 COG2426@1|root,arCOG01330@2157|Archaea,2XWK5@28890|Euryarchaeota,23VGF@183963|Halobacteria 183963|Halobacteria S Putative small multi-drug export protein - - - - - - - - - - - - Sm_multidrug_ex CMS3_k127_5110472_6 760192.Halhy_2972 5.945e-78 274.0 COG5337@1|root,COG5337@2|Bacteria,4P3EE@976|Bacteroidetes 976|Bacteroidetes M CotH kinase protein - - - ko:K06330 - - - - ko00000 - - - CotH CMS3_k127_5110472_10 164328.Phyra79286 3.094e-17 90.0 KOG4064@1|root,KOG4064@2759|Eukaryota,3QFAF@4776|Peronosporales 4776|Peronosporales E Cysteine dioxygenase type I - - 1.13.11.20 ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000 - - - CDO_I CMS3_k127_5110472_1 1123008.KB905696_gene2766 7.376e-274 851.0 COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,2FNK8@200643|Bacteroidia,22YF8@171551|Porphyromonadaceae 976|Bacteroidetes C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored CMS3_k127_5110472_7 1250278.JQNQ01000001_gene528 7.128e-77 265.0 COG1794@1|root,COG1794@2|Bacteria,4NI4F@976|Bacteroidetes,1IIB7@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the aspartate glutamate racemases family - - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race CMS3_k127_5110472_2 1408473.JHXO01000012_gene314 2.703e-230 721.0 COG0520@1|root,COG0520@2|Bacteria,4NERR@976|Bacteroidetes,2FWRC@200643|Bacteroidia 976|Bacteroidetes E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_5110472_8 1288963.ADIS_3302 1.27e-44 179.0 COG3356@1|root,COG3356@2|Bacteria,4NU9C@976|Bacteroidetes,47VT1@768503|Cytophagia 976|Bacteroidetes S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk CMS3_k127_5110472_4 886377.Murru_1834 1.405e-92 311.0 28J3W@1|root,2Z900@2|Bacteria,4NG4R@976|Bacteroidetes,1HYRY@117743|Flavobacteriia 976|Bacteroidetes S NIPSNAP - - - - - - - - - - - - NIPSNAP CMS3_k127_5123573_4 314285.KT71_02292 6.521e-34 130.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1S1X6@1236|Gammaproteobacteria 1236|Gammaproteobacteria E PFAM peptidase dimerisation domain protein - - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS3_k127_5123573_2 246197.MXAN_2554 5.502e-127 413.0 COG1028@1|root,COG1028@2|Bacteria,1MVKN@1224|Proteobacteria,433T9@68525|delta/epsilon subdivisions,2X3CY@28221|Deltaproteobacteria,2YTTY@29|Myxococcales 28221|Deltaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short CMS3_k127_5123573_3 1121904.ARBP01000026_gene637 1.386e-64 233.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,47NJ6@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_5123573_1 1173027.Mic7113_3165 2.022e-161 521.0 COG0520@1|root,COG0520@2|Bacteria,1G30B@1117|Cyanobacteria,1H8VP@1150|Oscillatoriales 1117|Cyanobacteria E PFAM Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 CMS3_k127_5123573_0 1279009.ADICEAN_00325 5.227e-186 598.0 COG1164@1|root,COG1164@2|Bacteria,4NFYH@976|Bacteroidetes,47JSX@768503|Cytophagia 976|Bacteroidetes E PFAM peptidase M3A and M3B thimet oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N CMS3_k127_5123758_0 1453500.AT05_03165 2.991e-21 109.0 COG4447@1|root,COG4447@2|Bacteria,4NEJ8@976|Bacteroidetes,1HYZP@117743|Flavobacteriia 976|Bacteroidetes O cellulase activity - - - - - - - - - - - - - CMS3_k127_5134678_1 886379.AEWI01000030_gene298 5.948e-36 147.0 COG2815@1|root,COG2815@2|Bacteria,4NSUI@976|Bacteroidetes,2FPS4@200643|Bacteroidia,3XJ68@558415|Marinilabiliaceae 976|Bacteroidetes S PASTA spk1 - 2.7.11.1,6.3.2.4 ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01001,ko01011 - - - PASTA CMS3_k127_5134678_0 714943.Mucpa_4144 7.379e-166 538.0 COG0513@1|root,COG0513@2|Bacteria,4NEJV@976|Bacteroidetes,1IQEP@117747|Sphingobacteriia 976|Bacteroidetes L Belongs to the DEAD box helicase family deaD - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C CMS3_k127_5134777_0 1484460.JSWG01000004_gene2638 1.232e-210 705.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1HZEZ@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_5148902_3 1250005.PHEL85_1698 1.358e-69 237.0 COG4660@1|root,COG4660@2|Bacteria 2|Bacteria C electron transport chain rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 2.3.1.243,4.2.99.18 ko:K02560,ko:K03613,ko:K10773 ko00540,ko01100,ko03410,map00540,map01100,map03410 M00060 R05075 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005,ko03400 - - - Rnf-Nqr CMS3_k127_5148902_2 1250005.PHEL85_1699 2.956e-98 323.0 COG4657@1|root,COG4657@2|Bacteria,4PPXA@976|Bacteroidetes,1I9U6@117743|Flavobacteriia 976|Bacteroidetes U Part of a membrane complex involved in electron transport - - - ko:K03617 - - - - ko00000 - - - Rnf-Nqr CMS3_k127_5148902_1 1250005.PHEL85_1700 6.808e-140 449.0 COG0369@1|root,COG0369@2|Bacteria 2|Bacteria C hydroxylamine reductase activity petH GO:0005575,GO:0005622,GO:0005623,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464 1.14.13.208,1.18.1.2,1.19.1.1 ko:K00528,ko:K02287,ko:K02641,ko:K15511 ko00195,ko00196,ko00362,ko01100,map00195,map00196,map00362,map01100 - R09555,R10159 RC01739 ko00000,ko00001,ko00194,ko01000 - - iJN678.petH CpcD,FAD_binding_6,Fer4,NAD_binding_1 CMS3_k127_5148902_0 1250005.PHEL85_1701 3.133e-150 479.0 COG2878@1|root,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes,1I99X@117743|Flavobacteriia 976|Bacteroidetes C Putative Fe-S cluster rnfB - - ko:K03616 - - - - ko00000 - - - FeS,Fer4 CMS3_k127_5148902_5 761193.Runsl_4362 4.231e-12 69.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,47U5P@768503|Cytophagia 976|Bacteroidetes S ATPase domain predominantly from Archaea - - - ko:K06921 - - - - ko00000 - - - ATPase_2 CMS3_k127_5153702_0 1227739.Hsw_1723 5.265e-307 957.0 COG2334@1|root,COG2334@2|Bacteria,4NEUT@976|Bacteroidetes,47M0W@768503|Cytophagia 976|Bacteroidetes S glucosidase - - - - - - - - - - - - Glyco_hydro_63 CMS3_k127_5153702_1 1122176.KB903536_gene1756 1.418e-78 264.0 COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1IPIA@117747|Sphingobacteriia 976|Bacteroidetes G Major Facilitator - - - ko:K16211 - - - - ko00000,ko02000 2.A.2.6 - - MFS_1 CMS3_k127_5153725_0 1286632.P278_26670 5.263e-141 457.0 COG0034@1|root,COG0034@2|Bacteria,4NFSM@976|Bacteroidetes,1HXZE@117743|Flavobacteriia 976|Bacteroidetes F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran CMS3_k127_5153725_1 1191523.MROS_0437 1.52e-46 173.0 COG0634@1|root,COG0634@2|Bacteria 2|Bacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 ko:K00760,ko:K00939,ko:K15780 ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130 M00049 R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319 RC00002,RC00063,RC00122 ko00000,ko00001,ko00002,ko01000,ko03016,ko04147 - - iHN637.CLJU_RS16720 ADK,Pribosyltran CMS3_k127_5153725_2 1237149.C900_02540 4.599e-22 96.0 COG4445@1|root,COG4445@2|Bacteria,4NP3S@976|Bacteroidetes,47Q34@768503|Cytophagia 976|Bacteroidetes FJ tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) - - - ko:K06169 - - - - ko00000,ko01000,ko03016 - - - MiaE CMS3_k127_5164811_2 1279009.ADICEAN_01838 1.42e-74 256.0 COG1216@1|root,COG1216@2|Bacteria,4NEJB@976|Bacteroidetes,47MPS@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 CMS3_k127_5164811_0 1124780.ANNU01000003_gene1440 2.542e-117 389.0 COG1215@1|root,COG1215@2|Bacteria,4NEM5@976|Bacteroidetes,47MUH@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3 CMS3_k127_5164811_1 1124780.ANNU01000036_gene18 2.442e-94 330.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NHKC@976|Bacteroidetes,47K54@768503|Cytophagia 976|Bacteroidetes M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - AAA_31,Wzz CMS3_k127_5165437_0 616991.JPOO01000003_gene1766 3.552e-238 746.0 COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes,1HY2W@117743|Flavobacteriia,23G90@178469|Arenibacter 976|Bacteroidetes E Pyridoxal-dependent decarboxylase conserved domain - - - - - - - - - - - - Pyridoxal_deC CMS3_k127_5165437_2 927658.AJUM01000034_gene457 8.934e-68 239.0 COG2003@1|root,COG2003@2|Bacteria,4NFBF@976|Bacteroidetes,2FNF3@200643|Bacteroidia,3XISE@558415|Marinilabiliaceae 976|Bacteroidetes L RadC-like JAB domain radC - - ko:K03630 - - - - ko00000 - - - RadC CMS3_k127_5165437_1 945713.IALB_1908 6.024e-177 574.0 COG0308@1|root,COG0308@2|Bacteria 2|Bacteria E peptide catabolic process - - - - - - - - - - - - Peptidase_M1 CMS3_k127_5165437_3 1313421.JHBV01000019_gene5344 2.431e-12 79.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_517399_4 3712.Bo3g100720.1 3.965e-14 76.0 COG0661@1|root,KOG1235@2759|Eukaryota,37PWH@33090|Viridiplantae,3G9ZN@35493|Streptophyta,3HVVT@3699|Brassicales 35493|Streptophyta S ABC1 family - GO:0000302,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007623,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009314,GO:0009416,GO:0009507,GO:0009526,GO:0009536,GO:0009605,GO:0009628,GO:0009636,GO:0009642,GO:0009644,GO:0009941,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010150,GO:0031667,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0033554,GO:0034599,GO:0042221,GO:0042493,GO:0042542,GO:0042592,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0046677,GO:0046686,GO:0048366,GO:0048367,GO:0048511,GO:0048583,GO:0048731,GO:0048827,GO:0048856,GO:0048878,GO:0050789,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0080134,GO:0090693,GO:0098771,GO:0099402,GO:1901031,GO:1901576,GO:1901700,GO:1902882,GO:1990641 - - - - - - - - - - ABC1 CMS3_k127_517399_3 926569.ANT_25440 4.136e-43 169.0 COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi 200795|Chloroflexi IQ COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - - - - - - - - - - adh_short CMS3_k127_517399_0 926549.KI421517_gene1467 9.348e-137 451.0 COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47M80@768503|Cytophagia 976|Bacteroidetes L Belongs to the DEAD box helicase family deaD - - - - - - - - - - - DEAD,Helicase_C CMS3_k127_517399_5 1236517.BAKO01000033_gene448 0.0003818 53.0 2BZQ4@1|root,32TE6@2|Bacteria,4NTHT@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_517399_2 760192.Halhy_4960 1.634e-88 297.0 COG3279@1|root,COG3279@2|Bacteria,4NIJQ@976|Bacteroidetes 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_517399_1 760192.Halhy_4961 3.73e-99 331.0 COG2972@1|root,COG2972@2|Bacteria,4NJPT@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase CMS3_k127_51893_0 870187.Thini_0272 5.439e-210 668.0 COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,4629A@72273|Thiotrichales 72273|Thiotrichales P STAS domain - - - - - - - - - - - - STAS,Sulfate_transp CMS3_k127_51893_1 1296416.JACB01000018_gene5287 1.041e-64 229.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,1HY05@117743|Flavobacteriia,2YKIT@290174|Aquimarina 976|Bacteroidetes G Glycosyl-hydrolase 97 N-terminal - - 3.2.1.20,3.2.1.3 ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01790,R01791,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31,GH97 - GH97_C,GH97_N,Glyco_hydro_97 CMS3_k127_5191392_2 696281.Desru_2195 1.276e-130 419.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,2610V@186807|Peptococcaceae 186801|Clostridia GT pyruvate phosphate dikinase, PEP ppdK - 2.7.9.1,2.7.9.2 ko:K01006,ko:K01007 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173,M00374 R00199,R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N CMS3_k127_5191392_9 1121904.ARBP01000003_gene6304 2.991e-21 95.0 COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,47K44@768503|Cytophagia 976|Bacteroidetes S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS CMS3_k127_5191392_3 1121904.ARBP01000053_gene472 1.722e-100 335.0 COG2207@1|root,COG2207@2|Bacteria,4NEHD@976|Bacteroidetes,47KBW@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator, AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_5191392_1 760192.Halhy_0714 2.992e-161 511.0 COG2207@1|root,COG2207@2|Bacteria,4NDYY@976|Bacteroidetes,1IQRI@117747|Sphingobacteriia 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - HTH_18 CMS3_k127_5191392_0 1121012.AUKX01000056_gene1656 1.16e-268 835.0 COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1HZ06@117743|Flavobacteriia 976|Bacteroidetes I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase CMS3_k127_5191392_5 743722.Sph21_0133 2.807e-66 228.0 COG1917@1|root,COG1917@2|Bacteria,4NNR7@976|Bacteroidetes,1IT7P@117747|Sphingobacteriia 976|Bacteroidetes S SnoaL-like domain - - - - - - - - - - - - DUF4440 CMS3_k127_5191392_4 886379.AEWI01000075_gene1958 1.183e-66 229.0 COG1917@1|root,COG1917@2|Bacteria,4NR0K@976|Bacteroidetes,2FXRD@200643|Bacteroidia 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 CMS3_k127_5191392_8 1004149.AFOE01000004_gene2477 3.186e-35 138.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,1HXJS@117743|Flavobacteriia 976|Bacteroidetes C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_5191392_7 1121897.AUGO01000009_gene2962 2.302e-43 163.0 COG4319@1|root,COG4319@2|Bacteria,4PFW3@976|Bacteroidetes,1IHV8@117743|Flavobacteriia,2NXWX@237|Flavobacterium 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 CMS3_k127_5192018_3 1121931.AUHG01000017_gene1557 3.262e-07 52.0 COG2988@1|root,COG2988@2|Bacteria,4NHWW@976|Bacteroidetes,1HZQK@117743|Flavobacteriia 976|Bacteroidetes E Succinylglutamate desuccinylase / Aspartoacylase family astE - 3.5.1.96 ko:K05526 ko00330,ko01100,map00330,map01100 - R00411 RC00064,RC00090 ko00000,ko00001,ko01000 - - - AstE_AspA CMS3_k127_5192018_2 1210884.HG799466_gene12570 8.162e-81 277.0 2CEY7@1|root,2Z8CG@2|Bacteria 2|Bacteria S membrane - - - - - - - - - - - - - CMS3_k127_5192018_0 204669.Acid345_1384 3.574e-242 764.0 COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia 204432|Acidobacteriia C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C CMS3_k127_5192018_1 675635.Psed_4589 1.388e-110 363.0 COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4DXT9@85010|Pseudonocardiales 201174|Actinobacteria C TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein sdhB1 - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0247c Fer2_3,Fer4_8 CMS3_k127_5193071_0 1121904.ARBP01000002_gene6706 7.033e-151 486.0 COG0399@1|root,COG0399@2|Bacteria,4NFQ8@976|Bacteroidetes,47K8X@768503|Cytophagia 976|Bacteroidetes E Belongs to the DegT DnrJ EryC1 family pseC - - - - - - - - - - - DegT_DnrJ_EryC1 CMS3_k127_5193071_1 1237149.C900_00515 7.042e-47 177.0 COG0750@1|root,COG0750@2|Bacteria,4NI5C@976|Bacteroidetes,47K57@768503|Cytophagia 976|Bacteroidetes M Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 CMS3_k127_5211359_0 232346.JHQL01000004_gene1660 1.583e-121 417.0 COG1700@1|root,COG1700@2|Bacteria,1MW8X@1224|Proteobacteria,1RS54@1236|Gammaproteobacteria,1XHGJ@135619|Oceanospirillales 135619|Oceanospirillales S PD-(D/E)XK nuclease superfamily - - - ko:K09124 - - - - ko00000 - - - DUF2357,PDDEXK_7 CMS3_k127_5211359_1 1250006.JHZZ01000001_gene1509 4.292e-106 356.0 COG1401@1|root,COG1401@2|Bacteria,4NKDZ@976|Bacteroidetes,1I5BE@117743|Flavobacteriia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - - - - - - - - - - AAA_5,DUF3578 CMS3_k127_5211359_2 1121904.ARBP01000007_gene2928 1.972e-46 172.0 COG4299@1|root,COG4299@2|Bacteria,4NDZF@976|Bacteroidetes,47JVV@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1624) - - - - - - - - - - - - DUF1624,DUF5009 CMS3_k127_5213489_3 1120968.AUBX01000011_gene2998 1.45e-57 203.0 COG1435@1|root,COG1435@2|Bacteria,4NE0S@976|Bacteroidetes,47K26@768503|Cytophagia 976|Bacteroidetes F SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_5213489_0 269798.CHU_1737 3.489e-174 557.0 COG0621@1|root,COG0621@2|Bacteria,4NE0R@976|Bacteroidetes,47MPX@768503|Cytophagia 976|Bacteroidetes J TIGRFAM MiaB-like tRNA modifying enzyme yqeV - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 CMS3_k127_5213489_4 743722.Sph21_2529 9.289e-54 198.0 COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1IQEU@117747|Sphingobacteriia 976|Bacteroidetes S S-adenosyl-l-methionine hydroxide adenosyltransferase fjo14 - - - - - - - - - - - SAM_adeno_trans CMS3_k127_5213489_2 1237149.C900_02699 4.049e-105 350.0 COG1702@1|root,COG1702@2|Bacteria,4NDYV@976|Bacteroidetes,47JUG@768503|Cytophagia 976|Bacteroidetes T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH CMS3_k127_5213489_1 1122176.KB903532_gene2576 4.461e-134 434.0 COG0074@1|root,COG0074@2|Bacteria,4NE6B@976|Bacteroidetes,1INZ1@117747|Sphingobacteriia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA,Succ_CoA_lig CMS3_k127_5213489_5 1341155.FSS13T_16740 1.305e-47 178.0 COG0742@1|root,COG0742@2|Bacteria,4NM7J@976|Bacteroidetes,1I185@117743|Flavobacteriia,2NSMC@237|Flavobacterium 976|Bacteroidetes L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 CMS3_k127_5213489_6 1469557.JSWF01000014_gene2510 3.364e-45 168.0 COG0669@1|root,COG0669@2|Bacteria,4NM84@976|Bacteroidetes,1I1BI@117743|Flavobacteriia 976|Bacteroidetes H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CMS3_k127_5213489_7 195250.CM001776_gene2210 4.563e-26 108.0 COG0173@1|root,COG0173@2|Bacteria,1G0W7@1117|Cyanobacteria,1GZ7Y@1129|Synechococcus 1117|Cyanobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iJN678.aspS GAD,tRNA-synt_2,tRNA_anti-codon CMS3_k127_5215421_3 1122176.KB903609_gene5178 2.215e-193 610.0 COG0365@1|root,COG0365@2|Bacteria,4NEAD@976|Bacteroidetes,1IPSM@117747|Sphingobacteriia 976|Bacteroidetes I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.17 ko:K01908 ko00640,ko01100,map00640,map01100 - R00926,R01354 RC00004,RC00043,RC00070,RC02816 ko00000,ko00001,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C CMS3_k127_5215421_10 1237149.C900_05039 1.88e-17 84.0 2C1EG@1|root,2Z7MZ@2|Bacteria,4NYQE@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5215421_8 1443665.JACA01000007_gene184 1.337e-48 176.0 2C1EG@1|root,2Z7MZ@2|Bacteria,4NYQE@976|Bacteroidetes,1IBSY@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5215421_2 1120966.AUBU01000002_gene2066 1.275e-240 757.0 COG2274@1|root,COG2274@2|Bacteria,4NE19@976|Bacteroidetes,47MDS@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran,Peptidase_C39 CMS3_k127_5215421_7 313606.M23134_01000 2.146e-60 216.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR,TetR_N CMS3_k127_5215421_4 1122176.KB903587_gene4435 2.177e-121 394.0 COG1028@1|root,COG1028@2|Bacteria,4NE45@976|Bacteroidetes,1IR0M@117747|Sphingobacteriia 976|Bacteroidetes IQ short-chain dehydrogenase ykuF - - ko:K13774 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short_C2 CMS3_k127_5215421_6 313606.M23134_00748 4.623e-82 280.0 COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes,47MUB@768503|Cytophagia 976|Bacteroidetes I PFAM Enoyl-CoA hydratase isomerase - - - - - - - - - - - - ECH_1 CMS3_k127_5215421_1 313606.M23134_01003 1.84e-249 786.0 COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes,47M7U@768503|Cytophagia 976|Bacteroidetes I PFAM Carbamoyl-phosphate synthase L chain, ATP binding - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 CMS3_k127_5215421_0 313606.M23134_01001 1.979e-272 846.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47JYJ@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS3_k127_5215421_5 880070.Cycma_2424 2.122e-112 379.0 COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47TIE@768503|Cytophagia 976|Bacteroidetes S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L CMS3_k127_5215421_9 880070.Cycma_1187 4.176e-44 178.0 COG2006@1|root,COG2006@2|Bacteria 2|Bacteria U 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - CBM9_1,CBM9_2,DUF362 CMS3_k127_5216218_5 1380384.JADN01000004_gene2356 1.094e-05 48.0 COG1587@1|root,COG1587@2|Bacteria,4NEQ3@976|Bacteroidetes,1HWMQ@117743|Flavobacteriia 976|Bacteroidetes H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 CMS3_k127_5216218_3 1392498.JQLH01000001_gene1190 1.174e-26 121.0 COG3064@1|root,COG3064@2|Bacteria,4NEVD@976|Bacteroidetes,1HWKC@117743|Flavobacteriia 976|Bacteroidetes M membrane - - - - - - - - - - - - PorP_SprF CMS3_k127_5216218_0 1279009.ADICEAN_01026 1.512e-122 403.0 COG1262@1|root,COG1262@2|Bacteria,4NGY2@976|Bacteroidetes,47KHB@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated lipoprotein GldK gldK - - - - - - - - - - - FGE-sulfatase CMS3_k127_5216218_1 153721.MYP_936 7.918e-65 230.0 28IG3@1|root,2Z8HM@2|Bacteria,4NFJR@976|Bacteroidetes,47MA3@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility-associated protein GldL gldL - - - - - - - - - - - - CMS3_k127_5216218_2 1123276.KB893245_gene1766 6.912e-43 177.0 28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated protein GldM gldM - - - - - - - - - - - GldM_C,GldM_N CMS3_k127_5216218_4 1356852.N008_06640 8.643e-14 81.0 2C97B@1|root,2ZAEJ@2|Bacteria,4NEK0@976|Bacteroidetes,47MC2@768503|Cytophagia 976|Bacteroidetes S TIGRFAM gliding motility associated protien GldN - - - - - - - - - - - - - CMS3_k127_5217896_2 925409.KI911562_gene2149 0.0001032 45.0 COG2910@1|root,COG2910@2|Bacteria,4PP94@976|Bacteroidetes,1IYBJ@117747|Sphingobacteriia 976|Bacteroidetes S NmrA-like family - - - - - - - - - - - - NAD_binding_10 CMS3_k127_5217896_1 517418.Ctha_0206 2.911e-46 174.0 COG2085@1|root,COG2085@2|Bacteria,1FF7Y@1090|Chlorobi 1090|Chlorobi S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored CMS3_k127_5217896_0 926549.KI421517_gene290 7.934e-174 550.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,47MC3@768503|Cytophagia 976|Bacteroidetes G fructose-bisphosphate aldolase, class II, yeast E. coli subtype fbaA - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase CMS3_k127_5221226_5 626522.GCWU000325_01791 4.529e-52 192.0 COG4123@1|root,COG4123@2|Bacteria,4NG1X@976|Bacteroidetes,2FMHH@200643|Bacteroidia,1WDFJ@1283313|Alloprevotella 976|Bacteroidetes J Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) yfiC GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016430,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.223 ko:K15460 - - - - ko00000,ko01000,ko03016 - - - MTS CMS3_k127_5221226_4 1313301.AUGC01000016_gene857 1.02e-53 196.0 COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes 976|Bacteroidetes L PFAM Uncharacterised ACR, COG1259 - - - ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR CMS3_k127_5221226_0 468059.AUHA01000003_gene1913 2.301e-105 351.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,1IPHN@117747|Sphingobacteriia 976|Bacteroidetes C Electron transfer flavoprotein etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha CMS3_k127_5221226_3 1189612.A33Q_1140 2.731e-69 242.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,47KZ2@768503|Cytophagia 976|Bacteroidetes C Electron transfer flavoprotein etfB - - ko:K03521 - - - - ko00000 - - - ETF CMS3_k127_5221226_8 929556.Solca_1915 2.42e-25 109.0 COG0457@1|root,COG0457@2|Bacteria,4PM5D@976|Bacteroidetes,1J0VV@117747|Sphingobacteriia 976|Bacteroidetes S TPR repeat - - - - - - - - - - - - TPR_19,TPR_6,TPR_8 CMS3_k127_5221226_7 880070.Cycma_2004 9.975e-32 131.0 COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,47PV2@768503|Cytophagia 976|Bacteroidetes O PFAM Scaffold protein Nfu NifU N terminal - - - - - - - - - - - - Nfu_N,NifU CMS3_k127_5221226_1 1237149.C900_02110 5.15e-81 276.0 COG0321@1|root,COG0321@2|Bacteria,4NE14@976|Bacteroidetes,47KKV@768503|Cytophagia 976|Bacteroidetes H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB CMS3_k127_5221226_2 1434325.AZQN01000006_gene3373 9.626e-75 261.0 COG0203@1|root,COG3743@1|root,COG0203@2|Bacteria,COG3743@2|Bacteria,4NNW0@976|Bacteroidetes,47PPE@768503|Cytophagia 976|Bacteroidetes J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 CMS3_k127_5221226_6 1121904.ARBP01000006_gene3820 6.125e-49 177.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,47JD5@768503|Cytophagia 976|Bacteroidetes K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L CMS3_k127_5223636_2 1121373.KB903665_gene3061 1.54e-88 307.0 COG1131@1|root,COG1131@2|Bacteria,4NFJD@976|Bacteroidetes,47TVR@768503|Cytophagia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_5223636_0 1279009.ADICEAN_00115 7.462e-119 398.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia 976|Bacteroidetes O PDZ domain (Also known as DHR or GLGF) htrA - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 CMS3_k127_5223636_1 242619.PG_0630 1.636e-91 307.0 COG0854@1|root,COG0854@2|Bacteria,4NF4Z@976|Bacteroidetes,2FM21@200643|Bacteroidia,22WZG@171551|Porphyromonadaceae 976|Bacteroidetes H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ CMS3_k127_5223636_3 309807.SRU_2752 7.443e-08 57.0 COG5512@1|root,COG5512@2|Bacteria,4PEV0@976|Bacteroidetes,1FJND@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 CMS3_k127_5224120_0 1313421.JHBV01000025_gene1010 5.908e-77 276.0 COG4995@1|root,COG4995@2|Bacteria,4NMR7@976|Bacteroidetes 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_8 CMS3_k127_5224120_1 313606.M23134_05594 2.153e-58 213.0 COG1352@1|root,COG1352@2|Bacteria,4NNFZ@976|Bacteroidetes,47Q6K@768503|Cytophagia 976|Bacteroidetes NT Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_25 CMS3_k127_5227033_0 391625.PPSIR1_35932 0.0 1159.0 COG2351@1|root,COG3409@1|root,COG2351@2|Bacteria,COG3409@2|Bacteria,1QWX0@1224|Proteobacteria 1224|Proteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - Hemopexin,PG_binding_1,VRP1 CMS3_k127_5233238_0 1265503.KB905170_gene176 2.229e-182 600.0 COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q7NV@267889|Colwelliaceae 1236|Gammaproteobacteria T Two component regulator propeller - - - ko:K19694 - - - - ko00000,ko01001,ko02022 - - - 7TMR-DISM_7TM,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y,dCache_1 CMS3_k127_5236358_5 1159488.SEQMU2_13345 0.0004055 49.0 COG1846@1|root,COG1846@2|Bacteria,1V97R@1239|Firmicutes,4HK27@91061|Bacilli,4GZYI@90964|Staphylococcaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 CMS3_k127_5236358_1 1004149.AFOE01000001_gene3021 9.168e-161 520.0 COG1541@1|root,COG1541@2|Bacteria,4PKJA@976|Bacteroidetes,1IJAQ@117743|Flavobacteriia 976|Bacteroidetes H GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 CMS3_k127_5236358_3 1121904.ARBP01000001_gene5830 5.546e-76 280.0 COG1305@1|root,COG1305@2|Bacteria,4NEKT@976|Bacteroidetes,47NCY@768503|Cytophagia 976|Bacteroidetes E Domain of Unknown Function with PDB structure (DUF3857) - - - - - - - - - - - - DUF3857,DUF3858,Transglut_core CMS3_k127_5236358_0 153721.MYP_1783 5.019e-198 628.0 COG0147@1|root,COG0147@2|Bacteria,4NFQ5@976|Bacteroidetes,47JMA@768503|Cytophagia 976|Bacteroidetes EH Anthranilate synthase component I, N terminal region trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind CMS3_k127_5236358_4 1121957.ATVL01000007_gene2307 8.258e-71 254.0 COG0512@1|root,COG0512@2|Bacteria,4NE4I@976|Bacteroidetes,47JZQ@768503|Cytophagia 976|Bacteroidetes EH TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase pabA - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase CMS3_k127_5236358_2 313606.M23134_01072 9.693e-96 327.0 COG0547@1|root,COG0547@2|Bacteria,4NH2J@976|Bacteroidetes,47KKR@768503|Cytophagia 976|Bacteroidetes E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 CMS3_k127_5236888_9 641524.ADICYQ_4672 5.358e-07 58.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family wzc - - - - - - - - - - - AAA_31,GNVR,Wzz CMS3_k127_5236888_5 1279009.ADICEAN_00921 1.153e-54 201.0 COG1596@1|root,COG1596@2|Bacteria,4NQV1@976|Bacteroidetes,47VPS@768503|Cytophagia 976|Bacteroidetes M Polysaccharide biosynthesis/export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export CMS3_k127_5236888_0 153721.MYP_1245 2.327e-218 682.0 COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia 976|Bacteroidetes P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily - - 2.7.1.25,2.7.7.4 ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - GTP_EFTU CMS3_k127_5236888_3 1121373.KB903662_gene63 4.989e-146 467.0 COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,47JCC@768503|Cytophagia 976|Bacteroidetes EH TIGRFAM sulfate adenylyltransferase, small subunit cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct CMS3_k127_5236888_4 1122176.KB903536_gene1821 4.212e-80 271.0 COG0529@1|root,COG0529@2|Bacteria,4NGCU@976|Bacteroidetes,1ITQ0@117747|Sphingobacteriia 976|Bacteroidetes P Catalyzes the synthesis of activated sulfate cysC GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase CMS3_k127_5236888_2 643867.Ftrac_0405 6.973e-160 532.0 COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,47KJ6@768503|Cytophagia 976|Bacteroidetes L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr CMS3_k127_5236888_10 468059.AUHA01000005_gene2573 1.468e-06 55.0 2EK3P@1|root,33DU3@2|Bacteria,4NXK2@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4296) - - - - - - - - - - - - DUF4296 CMS3_k127_5236888_6 1346330.M472_19635 4.247e-48 177.0 COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISG3@117747|Sphingobacteriia 976|Bacteroidetes H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - 2TM,DHFR_1 CMS3_k127_5236888_1 313606.M23134_04060 4.379e-208 653.0 COG4992@1|root,COG4992@2|Bacteria,4NE93@976|Bacteroidetes,47K80@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family rocD - 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_5236888_7 1107311.Q767_07690 1.318e-19 100.0 COG3735@1|root,COG3735@2|Bacteria,4NPI6@976|Bacteroidetes,1I2GB@117743|Flavobacteriia,2NUPB@237|Flavobacterium 976|Bacteroidetes S TraB family - - - ko:K09973 - - - - ko00000 - - - TraB CMS3_k127_5236888_8 211165.AJLN01000048_gene5998 1.601e-11 77.0 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JKNQ@1189|Stigonemataceae 1117|Cyanobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg CMS3_k127_5239868_2 1348635.BBJY01000016_gene3988 6.06e-06 50.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1SPRE@1236|Gammaproteobacteria,1XUSU@135623|Vibrionales 135623|Vibrionales L COG0084 Mg-dependent DNase tatD - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase CMS3_k127_5239868_1 313606.M23134_02819 2.918e-38 147.0 COG4276@1|root,COG4276@2|Bacteria,4NQDG@976|Bacteroidetes,47QF6@768503|Cytophagia 976|Bacteroidetes S Pfam Polyketide cyclase dehydrase and lipid transport - - - - - - - - - - - - - CMS3_k127_5239868_0 760192.Halhy_2510 1.182e-301 940.0 COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,1IRBZ@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF5117) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 CMS3_k127_5244246_0 1048983.EL17_06380 2.715e-198 641.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y6D@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_5244246_1 1499967.BAYZ01000009_gene5315 6.125e-10 60.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,2NP16@2323|unclassified Bacteria 2|Bacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 3.1.3.3,4.6.1.1 ko:K01768,ko:K07216,ko:K07315 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko03021 - - - AAA_16,GAF,GAF_2,Guanylate_cyc,HATPase_c,Hemerythrin,HisKA,PAS,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE CMS3_k127_5245377_1 694427.Palpr_0291 6e-84 287.0 COG4191@1|root,COG4191@2|Bacteria,4NEMP@976|Bacteroidetes,2FPJR@200643|Bacteroidia,22VVD@171551|Porphyromonadaceae 976|Bacteroidetes T Histidine kinase vicK - - - - - - - - - - - HATPase_c CMS3_k127_5245377_4 700598.Niako_4434 2.251e-37 144.0 COG0816@1|root,COG0816@2|Bacteria,4NQ8B@976|Bacteroidetes,1ISBS@117747|Sphingobacteriia 976|Bacteroidetes L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX CMS3_k127_5245377_2 504487.JCM19302_2139 2.511e-68 236.0 COG0242@1|root,COG0242@2|Bacteria,4NFB4@976|Bacteroidetes,1HX7M@117743|Flavobacteriia 976|Bacteroidetes J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase CMS3_k127_5245377_5 1191523.MROS_0160 1.519e-34 137.0 COG0838@1|root,COG0838@2|Bacteria 2|Bacteria C NADH dehydrogenase (ubiquinone) activity nuoA GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - e_coli_core.b2288,iAF1260.b2288,iAPECO1_1312.APECO1_4277,iB21_1397.B21_02173,iBWG_1329.BWG_2062,iE2348C_1286.E2348C_2428,iEC042_1314.EC042_2529,iEC55989_1330.EC55989_2532,iECABU_c1320.ECABU_c26200,iECBD_1354.ECBD_1373,iECB_1328.ECB_02213,iECDH10B_1368.ECDH10B_2450,iECDH1ME8569_1439.ECDH1ME8569_2225,iECD_1391.ECD_02213,iECED1_1282.ECED1_2752,iECH74115_1262.ECH74115_3427,iECIAI1_1343.ECIAI1_2362,iECIAI39_1322.ECIAI39_2435,iECO103_1326.ECO103_2752,iECO26_1355.ECO26_3276,iECOK1_1307.ECOK1_2521,iECP_1309.ECP_2327,iECS88_1305.ECS88_2435,iECSE_1348.ECSE_2545,iECSP_1301.ECSP_3162,iECUMN_1333.ECUMN_2627,iECW_1372.ECW_m2476,iECs_1301.ECs3172,iEKO11_1354.EKO11_1479,iETEC_1333.ETEC_2423,iEcDH1_1363.EcDH1_1369,iEcE24377_1341.EcE24377A_2581,iEcHS_1320.EcHS_A2437,iEcSMS35_1347.EcSMS35_2442,iEcolC_1368.EcolC_1364,iG2583_1286.G2583_2825,iJN746.PP_4119,iJO1366.b2288,iJR904.b2288,iLF82_1304.LF82_1539,iNRG857_1313.NRG857_11585,iSBO_1134.SBO_2321,iSDY_1059.SDY_2484,iSFV_1184.SFV_2355,iSF_1195.SF2364,iSFxv_1172.SFxv_2608,iSSON_1240.SSON_2345,iS_1188.S2499,iSbBS512_1146.SbBS512_E2664,iUMN146_1321.UM146_05375,iUTI89_1310.UTI89_C2568,iWFL_1372.ECW_m2476,iY75_1357.Y75_RS11995,ic_1306.c2829 Oxidored_q4 CMS3_k127_5245377_0 1121104.AQXH01000001_gene1245 2.897e-85 284.0 COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 CMS3_k127_5245377_3 1122176.KB903534_gene2249 1.122e-47 179.0 COG2981@1|root,COG2981@2|Bacteria,4NHXY@976|Bacteroidetes,1IYWB@117747|Sphingobacteriia 976|Bacteroidetes E Etoposide-induced protein 2.4 (EI24) - - - ko:K06203 - - - - ko00000 - - - EI24 CMS3_k127_5251660_1 760192.Halhy_1697 1.546e-16 94.0 COG1672@1|root,COG1672@2|Bacteria,4NR06@976|Bacteroidetes 976|Bacteroidetes L Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - CMS3_k127_5251660_0 1094466.KQS_09755 5.484e-57 223.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1HYG0@117743|Flavobacteriia,2NV11@237|Flavobacterium 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS3_k127_5258762_0 1123248.KB893370_gene5141 0.0 1671.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,1J0QI@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2 CMS3_k127_5258762_3 684949.ATTJ01000002_gene112 9.784e-72 247.0 COG0346@1|root,COG0400@1|root,COG0346@2|Bacteria,COG0400@2|Bacteria,1WICF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E glyoxalase bleomycin resistance protein dioxygenase - - - ko:K15975 - - - - ko00000 - - - Abhydrolase_2,Glyoxalase CMS3_k127_5258762_2 1185876.BN8_05991 3.261e-97 327.0 COG0346@1|root,COG0346@2|Bacteria,4NGE0@976|Bacteroidetes,47KJP@768503|Cytophagia 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K15975 - - - - ko00000 - - - Glyoxalase CMS3_k127_5258762_1 391603.FBALC1_13072 0.0 1100.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,1HYJJ@117743|Flavobacteriia 976|Bacteroidetes M Tricorn protease homolog - - - - - - - - - - - - PD40,PDZ_2,Peptidase_S41,Tricorn_C1 CMS3_k127_5261170_1 1313301.AUGC01000017_gene795 2.424e-119 404.0 COG1807@1|root,COG1807@2|Bacteria,4NE7V@976|Bacteroidetes 976|Bacteroidetes M COG1807 4-amino-4-deoxy-L-arabinose transferase and related - - - - - - - - - - - - PMT_2 CMS3_k127_5261170_2 1283300.ATXB01000001_gene2271 4.711e-90 308.0 COG0392@1|root,COG0392@2|Bacteria 2|Bacteria M lysyltransferase activity mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM CMS3_k127_5261170_0 714943.Mucpa_0336 8.017e-171 543.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,1IPEF@117747|Sphingobacteriia 976|Bacteroidetes I Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) accD5 - - - - - - - - - - - Carboxyl_trans CMS3_k127_5264190_5 1279009.ADICEAN_03159 1.062e-83 286.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47MGE@768503|Cytophagia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - FG-GAP,UnbV_ASPIC,VCBS CMS3_k127_5264190_4 760192.Halhy_1520 5.479e-93 329.0 COG3391@1|root,COG4935@1|root,COG3391@2|Bacteria,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Tail_P2_I CMS3_k127_5264190_2 760192.Halhy_1514 2.816e-173 557.0 COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,1IQKD@117747|Sphingobacteriia 976|Bacteroidetes M SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_5264190_1 388413.ALPR1_19733 1.307e-311 982.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y44@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5264190_6 1120965.AUBV01000003_gene530 1.344e-42 165.0 2BTVE@1|root,32P38@2|Bacteria,4NRR1@976|Bacteroidetes,47PZ2@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5264190_0 760192.Halhy_1519 0.0 1480.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1IVZC@117747|Sphingobacteriia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - FG-GAP,UnbV_ASPIC,VCBS CMS3_k127_5264190_3 643867.Ftrac_0734 6.236e-98 331.0 COG1609@1|root,COG1609@2|Bacteria,4NDW6@976|Bacteroidetes,47MGC@768503|Cytophagia 976|Bacteroidetes K PFAM Periplasmic binding protein LacI transcriptional regulator cytR - - ko:K02529,ko:K05499 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 CMS3_k127_5281601_3 1279009.ADICEAN_00924 9.549e-154 513.0 COG3250@1|root,COG4124@1|root,COG3250@2|Bacteria,COG4124@2|Bacteria,4PPF2@976|Bacteroidetes 976|Bacteroidetes G Glycosyl hydrolase family 26 - - - - - - - - - - - - Glyco_hydro_26 CMS3_k127_5281601_4 926549.KI421517_gene3152 4.181e-109 369.0 COG3250@1|root,COG3250@2|Bacteria,4NHRV@976|Bacteroidetes,47JP4@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolases family 2, TIM barrel domain - - - - - - - - - - - - Glyco_hydro_2_C CMS3_k127_5281601_2 313606.M23134_01128 2.647e-163 521.0 COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47MDV@768503|Cytophagia 976|Bacteroidetes S PFAM Amidohydrolase 2 - - - - - - - - - - - - Amidohydro_2 CMS3_k127_5281601_6 1121904.ARBP01000006_gene3769 3.602e-80 278.0 COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes 976|Bacteroidetes M Transglycosylase SLT domain - - - - - - - - - - - - SLT CMS3_k127_5281601_5 1121904.ARBP01000017_gene5131 1.566e-100 344.0 2EBH5@1|root,335HP@2|Bacteria,4NW0F@976|Bacteroidetes,47VF8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5281601_1 1121904.ARBP01000010_gene2295 1.388e-185 593.0 COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia 976|Bacteroidetes Q PFAM D-aminoacylase, C-terminal region - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 CMS3_k127_5281601_0 1121904.ARBP01000003_gene6372 3.233e-286 888.0 COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,47K7D@768503|Cytophagia 976|Bacteroidetes P esterase - - - - - - - - - - - - Esterase CMS3_k127_5281601_7 1124780.ANNU01000034_gene1345 4.43e-16 87.0 2EBB5@1|root,335BV@2|Bacteria,4NUQ0@976|Bacteroidetes,47WJ2@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5284216_0 1237149.C900_00840 1.13e-116 401.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5289054_2 1541065.JRFE01000058_gene5645 5.439e-16 84.0 COG0553@1|root,COG3886@1|root,COG0553@2|Bacteria,COG3886@2|Bacteria,1FZVD@1117|Cyanobacteria 1117|Cyanobacteria L Helicase conserved C-terminal domain - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N CMS3_k127_5289054_0 1317122.ATO12_05480 9.222e-163 523.0 COG0464@1|root,COG0464@2|Bacteria,4NFWG@976|Bacteroidetes,1HZA4@117743|Flavobacteriia,2YI1T@290174|Aquimarina 976|Bacteroidetes O ATPase family associated with various cellular activities (AAA) - - - - - - - - - - - - AAA CMS3_k127_5289054_1 1317122.ATO12_05485 2.461e-30 122.0 COG3064@1|root,COG3064@2|Bacteria,4P218@976|Bacteroidetes,1I87T@117743|Flavobacteriia,2YKU4@290174|Aquimarina 976|Bacteroidetes M Domain of unknown function (DUF4157) - - - - - - - - - - - - DUF4157 CMS3_k127_5290137_4 391603.FBALC1_12572 1.012e-26 126.0 COG3209@1|root,COG5295@1|root,COG3209@2|Bacteria,COG5295@2|Bacteria,4PKW4@976|Bacteroidetes,1I1PS@117743|Flavobacteriia 976|Bacteroidetes MUW Chaperone of endosialidase - - - - - - - - - - - - Peptidase_S74,YadA_head CMS3_k127_5290137_7 1341155.FSS13T_25380 6.702e-05 53.0 COG1404@1|root,COG1974@1|root,COG3291@1|root,COG1404@2|Bacteria,COG1974@2|Bacteria,COG3291@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia 976|Bacteroidetes O Belongs to the peptidase S8 family - - - - - - - - - - - - DUF5011,MAM,Peptidase_S8,fn3 CMS3_k127_5290137_1 1121007.AUML01000016_gene243 1.389e-129 450.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia,2YHT1@290174|Aquimarina 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_8 CMS3_k127_5290137_3 1279009.ADICEAN_04235 2.514e-70 241.0 COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,47PQS@768503|Cytophagia 976|Bacteroidetes F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC CMS3_k127_5290137_0 1279009.ADICEAN_04234 1.627e-147 477.0 COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia 976|Bacteroidetes F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp CMS3_k127_5290137_2 1124780.ANNU01000078_gene755 6.954e-83 291.0 COG4409@1|root,COG4409@2|Bacteria,4NI5M@976|Bacteroidetes,47JYZ@768503|Cytophagia 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 CMS3_k127_5290137_6 755732.Fluta_1728 6.457e-09 64.0 COG3206@1|root,COG3206@2|Bacteria,4NWAG@976|Bacteroidetes,1I785@117743|Flavobacteriia,2PAYX@246874|Cryomorphaceae 976|Bacteroidetes M Chain length determinant protein - - - - - - - - - - - - Wzz CMS3_k127_5290137_5 1123057.P872_01205 8.798e-18 87.0 2E4YQ@1|root,32ZSH@2|Bacteria,4NVKX@976|Bacteroidetes,47RX3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5291152_14 1500257.JQNM01000024_gene43 3.219e-26 108.0 COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2TQPI@28211|Alphaproteobacteria,4BB7T@82115|Rhizobiaceae 28211|Alphaproteobacteria M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CMS3_k127_5291152_9 929556.Solca_3349 1.677e-60 213.0 COG1898@1|root,COG1898@2|Bacteria,4NNKW@976|Bacteroidetes,1IRUX@117747|Sphingobacteriia 976|Bacteroidetes M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rfbC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom CMS3_k127_5291152_1 518766.Rmar_1858 9.175e-160 509.0 COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes M GDP-mannose 4,6 dehydratase - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd CMS3_k127_5291152_0 1197477.IA57_05230 2.14e-192 609.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,1HWQV@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the UDP-glucose GDP-mannose dehydrogenase family tuaD - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N CMS3_k127_5291152_2 926562.Oweho_1671 2.372e-133 435.0 COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,1HXWJ@117743|Flavobacteriia,2PA9E@246874|Cryomorphaceae 976|Bacteroidetes E PFAM DegT DnrJ EryC1 StrS aminotransferase family degT - - - - - - - - - - - DegT_DnrJ_EryC1 CMS3_k127_5291152_13 755732.Fluta_2041 4.44e-30 130.0 2EA9Q@1|root,334E4@2|Bacteria,4NX5I@976|Bacteroidetes,1IASC@117743|Flavobacteriia,2PB5U@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5291152_6 1178825.ALIH01000007_gene1641 2.505e-94 324.0 COG1519@1|root,COG1519@2|Bacteria,4NESA@976|Bacteroidetes,1HWPY@117743|Flavobacteriia 976|Bacteroidetes M Transferase waaA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N CMS3_k127_5291152_3 696747.NIES39_E00230 3.939e-131 427.0 COG0115@1|root,COG0115@2|Bacteria,1G1GM@1117|Cyanobacteria,1H8CZ@1150|Oscillatoriales 1117|Cyanobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 CMS3_k127_5291152_10 153721.MYP_1846 1.004e-57 225.0 2F1WD@1|root,33UW2@2|Bacteria,4P2AY@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5291152_5 755732.Fluta_1225 3.033e-121 435.0 COG3023@1|root,COG3023@2|Bacteria,4NN1U@976|Bacteroidetes 976|Bacteroidetes V COGs COG3023 Negative regulator of beta-lactamase expression - - - - - - - - - - - - Amidase_2,CUB CMS3_k127_5291152_8 1158318.ATXC01000002_gene1476 3.193e-65 236.0 COG0075@1|root,COG0075@2|Bacteria,2G3RP@200783|Aquificae 200783|Aquificae E PFAM aminotransferase class V - - - - - - - - - - - - Aminotran_5 CMS3_k127_5291152_7 1131462.DCF50_p1959 6.548e-70 246.0 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia,261G8@186807|Peptococcaceae 186801|Clostridia S PFAM NAD dependent epimerase dehydratase family - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase CMS3_k127_5291152_4 1168034.FH5T_19705 4.821e-125 408.0 COG0667@1|root,COG0667@2|Bacteria,4NF06@976|Bacteroidetes,2G2UC@200643|Bacteroidia 976|Bacteroidetes C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CMS3_k127_5291152_15 1379698.RBG1_1C00001G1377 4.363e-23 115.0 COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase CMS3_k127_5291152_12 709991.Odosp_0625 5.562e-47 176.0 COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,2FSJZ@200643|Bacteroidia,231US@171551|Porphyromonadaceae 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5291152_11 313606.M23134_05019 1.911e-51 183.0 COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,47KGU@768503|Cytophagia 976|Bacteroidetes S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07098 - - - - ko00000 - - - Metallophos CMS3_k127_5291685_1 1122176.KB903576_gene4994 2.111e-211 670.0 COG0574@1|root,COG0574@2|Bacteria,4NH4R@976|Bacteroidetes 976|Bacteroidetes G Pyruvate phosphate dikinase - - - - - - - - - - - - PPDK_N CMS3_k127_5291685_5 1313421.JHBV01000004_gene758 1.281e-05 55.0 28JA7@1|root,2Z951@2|Bacteria,4NKY9@976|Bacteroidetes 976|Bacteroidetes S Parallel beta-helix repeats - - - - - - - - - - - - CotH CMS3_k127_5291685_2 402612.FP1413 5.38e-131 432.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2NSWF@237|Flavobacterium 976|Bacteroidetes M Membrane bound O-acyl transferase, MBOAT family protein - - - ko:K19294 - - - - ko00000 - - - MBOAT CMS3_k127_5291685_3 402612.FP1412 1.491e-45 180.0 2DKXU@1|root,30TFF@2|Bacteria,4NPBR@976|Bacteroidetes,1I8N7@117743|Flavobacteriia 976|Bacteroidetes S SGNH hydrolase-like domain, acetyltransferase AlgX - - - - - - - - - - - - ALGX CMS3_k127_5291685_4 379066.GAU_2404 9.548e-15 79.0 COG1629@1|root,COG4771@2|Bacteria,1ZURA@142182|Gemmatimonadetes 142182|Gemmatimonadetes P TonB dependent receptor - - - - - - - - - - - - Plug,TonB_dep_Rec CMS3_k127_5291685_0 1392498.JQLH01000001_gene3635 2.943e-212 670.0 COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia,2PIED@252356|Maribacter 976|Bacteroidetes P Sodium:sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp CMS3_k127_5291975_1 1124780.ANNU01000005_gene2467 8.597e-170 542.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 CMS3_k127_5291975_4 1270196.JCKI01000003_gene1980 1.105e-30 122.0 COG0759@1|root,COG0759@2|Bacteria,4NV1N@976|Bacteroidetes,1ITUQ@117747|Sphingobacteriia 976|Bacteroidetes S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic CMS3_k127_5291975_0 1237149.C900_01850 5.391e-181 575.0 COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes 976|Bacteroidetes G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - BNR_2 CMS3_k127_5291975_9 455632.SGR_5941 0.0001177 54.0 COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria 201174|Actinobacteria S phosphatidylinositol metabolic process - - - ko:K13671 - - - - ko00000,ko01000,ko01003 - GT87 - GT87 CMS3_k127_5291975_5 1227739.Hsw_1284 1.983e-28 119.0 2BJ0K@1|root,32D95@2|Bacteria,4NQN9@976|Bacteroidetes,47QR4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5291975_2 313606.M23134_01935 7.539e-160 511.0 COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 CMS3_k127_5291975_8 1123057.P872_02850 9.859e-11 69.0 2AE6H@1|root,3140B@2|Bacteria,4NSDV@976|Bacteroidetes,47RV6@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5291975_3 1185876.BN8_02404 7.279e-121 398.0 COG0673@1|root,COG0673@2|Bacteria,4NM3P@976|Bacteroidetes,47P07@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_5291975_6 1121904.ARBP01000006_gene3981 1.715e-17 84.0 COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,47S09@768503|Cytophagia 976|Bacteroidetes U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 CMS3_k127_5292945_3 153721.MYP_4656 4.38e-66 243.0 COG1752@1|root,COG1752@2|Bacteria,4NF97@976|Bacteroidetes,47KND@768503|Cytophagia 976|Bacteroidetes S Esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin CMS3_k127_5292945_0 649638.Trad_1860 2.153e-224 702.0 COG0114@1|root,COG0114@2|Bacteria,1WJ9Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 CMS3_k127_5292945_5 491205.JARQ01000003_gene1947 2.377e-24 108.0 COG2137@1|root,COG2137@2|Bacteria,4NSAS@976|Bacteroidetes,1I25J@117743|Flavobacteriia,3ZRQZ@59732|Chryseobacterium 976|Bacteroidetes S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX CMS3_k127_5292945_1 1313421.JHBV01000035_gene2506 2.853e-115 395.0 COG0457@1|root,COG0457@2|Bacteria,4NDTY@976|Bacteroidetes,1IPV6@117747|Sphingobacteriia 976|Bacteroidetes S Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,Paired_CXXCH_1,TPR_2,TPR_8 CMS3_k127_5292945_2 1237149.C900_04487 1.543e-108 365.0 COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,47KP1@768503|Cytophagia 976|Bacteroidetes S PFAM Metal-dependent phosphohydrolase, HD - - - - - - - - - - - - HD CMS3_k127_5292945_4 227377.CBU_0630 1.118e-33 139.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1JD4Y@118969|Legionellales 118969|Legionellales M peptidyl-prolyl cis-trans isomerase mip GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044462,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N CMS3_k127_5300544_3 760192.Halhy_5532 5.453e-30 132.0 2AHAR@1|root,317M3@2|Bacteria,4P8RB@976|Bacteroidetes,1IZUZ@117747|Sphingobacteriia 760192.Halhy_5532|- S IMG reference gene - - - - - - - - - - - - - CMS3_k127_5300544_1 760192.Halhy_4332 1.695e-80 290.0 COG1262@1|root,COG1672@1|root,COG3064@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,COG3064@2|Bacteria,4PN7M@976|Bacteroidetes,1IXXU@117747|Sphingobacteriia 976|Bacteroidetes M Membrane - - - - - - - - - - - - - CMS3_k127_5300544_0 1313421.JHBV01000022_gene4703 1.072e-165 531.0 COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,1IS79@117747|Sphingobacteriia 976|Bacteroidetes P Pfam Sodium hydrogen exchanger - - - - - - - - - - - - Na_H_Exchanger CMS3_k127_5300544_2 1122179.KB890431_gene4267 2.042e-47 179.0 2C34E@1|root,2ZI9F@2|Bacteria,4P7UE@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5300544_4 1122176.KB903536_gene1827 7.114e-13 70.0 COG0464@1|root,COG0464@2|Bacteria,4P0AA@976|Bacteroidetes 976|Bacteroidetes O growth - - - - - - - - - - - - - CMS3_k127_5303677_2 1434325.AZQN01000002_gene744 3.576e-103 340.0 COG1028@1|root,COG1028@2|Bacteria,4NFTU@976|Bacteroidetes,47N90@768503|Cytophagia 976|Bacteroidetes IQ KR domain fabG3 - 1.1.1.100,1.1.1.36 ko:K00023,ko:K00059 ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212 M00083,M00373,M00572 R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00103,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_5303677_7 1121481.AUAS01000005_gene1794 7.891e-30 124.0 COG4706@1|root,COG4706@2|Bacteria,4NSB5@976|Bacteroidetes,47Y6Y@768503|Cytophagia 976|Bacteroidetes I dehydratase - - - - - - - - - - - - - CMS3_k127_5303677_8 575615.HMPREF0670_01521 9.256e-23 100.0 COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes 976|Bacteroidetes IQ acyl carrier protein acpP2 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_5303677_1 471854.Dfer_1989 7.626e-136 442.0 COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,47N4W@768503|Cytophagia 976|Bacteroidetes IQ Beta-ketoacyl synthase, C-terminal domain - - 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_5303677_5 1121481.AUAS01000005_gene1788 3.872e-71 251.0 COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,47PQU@768503|Cytophagia 976|Bacteroidetes IQ Beta-ketoacyl synthase, N-terminal domain - - - - - - - - - - - - Ketoacyl-synt_2 CMS3_k127_5303677_9 1434325.AZQN01000002_gene729 5.194e-21 96.0 COG0764@1|root,COG0764@2|Bacteria,4NSGQ@976|Bacteroidetes,47SUB@768503|Cytophagia 976|Bacteroidetes I FabA-like domain fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CMS3_k127_5303677_6 1286632.P278_03710 5.876e-47 171.0 COG2044@1|root,COG2044@2|Bacteria,4P2I4@976|Bacteroidetes,1I8SH@117743|Flavobacteriia 976|Bacteroidetes S DsrE/DsrF-like family - - - - - - - - - - - - DrsE CMS3_k127_5303677_10 4787.PITG_02767T0 6.716e-15 83.0 KOG4064@1|root,KOG4064@2759|Eukaryota,3QFAF@4776|Peronosporales 4776|Peronosporales E Cysteine dioxygenase type I - - 1.13.11.20 ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000 - - - CDO_I CMS3_k127_5303677_4 1403819.BATR01000133_gene4702 1.377e-73 257.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator exsA GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1903506,GO:2000112,GO:2001141 - ko:K20968 ko02025,map02025 - - - ko00000,ko00001,ko03000 - - - HTH_18 CMS3_k127_5303677_3 153721.MYP_2780 2.964e-97 335.0 COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,47JKK@768503|Cytophagia 976|Bacteroidetes MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_5303677_0 391587.KAOT1_19632 6.612e-138 452.0 COG0845@1|root,COG0845@2|Bacteria,4NFEK@976|Bacteroidetes,1HXDY@117743|Flavobacteriia 976|Bacteroidetes M Biotin attachment protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,OEP CMS3_k127_5303677_11 9258.ENSOANP00000023383 0.0003617 44.0 COG1132@1|root,KOG0054@2759|Eukaryota,38CH6@33154|Opisthokonta,3BAG8@33208|Metazoa,3CSJ8@33213|Bilateria,480HS@7711|Chordata,491MI@7742|Vertebrata,3J5G2@40674|Mammalia 33208|Metazoa Q ATPase activity, coupled to transmembrane movement of substances ABCC12 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K05668,ko:K05672,ko:K21863 ko01523,ko02010,map01523,map02010 - - - ko00000,ko00001,ko02000,ko04040 1.A.1.11.15,3.A.1.208,3.A.1.208.15 - - ABC_membrane,ABC_tran CMS3_k127_5307372_2 929556.Solca_4228 2.267e-122 398.0 COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1IQ33@117747|Sphingobacteriia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 CMS3_k127_5307372_1 1124780.ANNU01000006_gene2792 2.242e-134 435.0 COG0667@1|root,COG0667@2|Bacteria,4NHA1@976|Bacteroidetes,47NMZ@768503|Cytophagia 976|Bacteroidetes C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red CMS3_k127_5307372_0 485917.Phep_1588 6.942e-170 540.0 COG1060@1|root,COG1060@2|Bacteria,4NGTU@976|Bacteroidetes,1IQI2@117747|Sphingobacteriia 976|Bacteroidetes H Radical SAM mqnC - 1.21.98.1 ko:K11784 ko00130,ko01110,map00130,map01110 - R08588 RC02329 ko00000,ko00001,ko01000 - - - Radical_SAM CMS3_k127_5307372_4 1434325.AZQN01000003_gene2775 1.557e-81 297.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,47KBN@768503|Cytophagia 976|Bacteroidetes O peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,Rotamase_3,SurA_N_2 CMS3_k127_5307372_3 1237149.C900_03150 6.498e-88 292.0 COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47PB4@768503|Cytophagia 976|Bacteroidetes O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR CMS3_k127_5311878_1 1121904.ARBP01000015_gene179 4.53e-162 539.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5311878_0 313606.M23134_01395 7.542e-183 586.0 COG4262@1|root,COG4262@2|Bacteria,4NFVH@976|Bacteroidetes,47NJJ@768503|Cytophagia 976|Bacteroidetes S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Spermine_synth CMS3_k127_5312122_3 641524.ADICYQ_0753 5.577e-68 237.0 COG1331@1|root,COG1331@2|Bacteria,4NSMA@976|Bacteroidetes 976|Bacteroidetes O pectate lyase - - - - - - - - - - - - Pec_lyase CMS3_k127_5312122_2 760192.Halhy_5983 1.485e-226 715.0 COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia 976|Bacteroidetes G Glycosyl hydrolase family 20, catalytic domain - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b CMS3_k127_5312122_0 1286632.P278_07760 1.399e-296 928.0 COG3345@1|root,COG3345@2|Bacteria,4PMM4@976|Bacteroidetes 976|Bacteroidetes G alpha-galactosidase - - - - - - - - - - - - - CMS3_k127_5312122_1 313603.FB2170_00810 9.452e-243 758.0 COG2939@1|root,COG2939@2|Bacteria,4NF48@976|Bacteroidetes,1IE70@117743|Flavobacteriia,2PG2X@252356|Maribacter 976|Bacteroidetes E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 CMS3_k127_5312122_4 467661.RKLH11_3573 8.984e-21 96.0 COG5441@1|root,COG5441@2|Bacteria,1MX45@1224|Proteobacteria,2TUHA@28211|Alphaproteobacteria,3ZGA3@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria S Uncharacterised protein family (UPF0261) - - - - - - - - - - - - ABC_tran,UPF0261 CMS3_k127_5312227_0 1185876.BN8_05593 3.793e-205 647.0 COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia 976|Bacteroidetes I TIGRFAM acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CMS3_k127_5312227_3 1122621.ATZA01000017_gene3932 2.34e-41 158.0 COG0511@1|root,COG0511@2|Bacteria,4NM8U@976|Bacteroidetes,1ISET@117747|Sphingobacteriia 976|Bacteroidetes I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl CMS3_k127_5312227_2 1122179.KB890413_gene4949 6.577e-71 244.0 COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,1IP45@117747|Sphingobacteriia 976|Bacteroidetes J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CMS3_k127_5312227_1 1346330.M472_18480 1.16e-140 453.0 COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,1IPRR@117747|Sphingobacteriia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_5312662_2 1121904.ARBP01000010_gene2450 3.79e-65 230.0 COG3483@1|root,COG3483@2|Bacteria,4NFG4@976|Bacteroidetes,47KCQ@768503|Cytophagia 976|Bacteroidetes E Tryptophan 2,3-dioxygenase kynA - 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase CMS3_k127_5312662_1 761193.Runsl_2411 2.726e-75 269.0 COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,47JCK@768503|Cytophagia 976|Bacteroidetes CP COGs COG1668 ABC-type Na efflux pump permease component natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS3_k127_5312662_0 471854.Dfer_4965 1.872e-88 301.0 COG4152@1|root,COG4152@2|Bacteria,4NEJE@976|Bacteroidetes,47KYF@768503|Cytophagia 976|Bacteroidetes S PFAM ABC transporter natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 CMS3_k127_5312662_3 643867.Ftrac_1942 8.555e-10 69.0 2BK1P@1|root,32EEX@2|Bacteria,4NRXN@976|Bacteroidetes,47QMH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5319830_7 313606.M23134_07140 1.464e-41 160.0 COG1309@1|root,COG1309@2|Bacteria,4NKWP@976|Bacteroidetes,47XJF@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CMS3_k127_5319830_9 1313421.JHBV01000020_gene5261 2.812e-36 142.0 COG2050@1|root,COG2050@2|Bacteria,4NRJF@976|Bacteroidetes 976|Bacteroidetes Q Thioesterase superfamily - - - - - - - - - - - - 4HBT CMS3_k127_5319830_2 1242864.D187_003204 2.655e-139 450.0 COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,43EAF@68525|delta/epsilon subdivisions,2X34W@28221|Deltaproteobacteria,2YUA3@29|Myxococcales 28221|Deltaproteobacteria S N-terminal domain of oxidoreductase - - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N CMS3_k127_5319830_4 1121904.ARBP01000004_gene1046 1.054e-83 284.0 COG1028@1|root,COG1028@2|Bacteria,4NEUB@976|Bacteroidetes,47MT3@768503|Cytophagia 976|Bacteroidetes IQ KR domain - - 1.3.1.25 ko:K05783 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00551 R00813,R05292,R05293,R05309,R05314,R08111,R08112,R08113 RC00271,RC01326,RC01327 br01602,ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 CMS3_k127_5319830_1 313606.M23134_00150 6.029e-201 640.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,47K61@768503|Cytophagia 976|Bacteroidetes I AMP-binding enzyme - - - - - - - - - - - - AMP-binding CMS3_k127_5319830_0 1121904.ARBP01000004_gene994 9.799e-285 884.0 COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,47K4P@768503|Cytophagia 976|Bacteroidetes M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C CMS3_k127_5319830_10 1121957.ATVL01000006_gene3445 5.563e-35 145.0 COG0614@1|root,COG0614@2|Bacteria,4PJ01@976|Bacteroidetes,47PWV@768503|Cytophagia 976|Bacteroidetes P Periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 CMS3_k127_5319830_6 1121904.ARBP01000026_gene622 4.253e-62 221.0 COG1272@1|root,COG1272@2|Bacteria,4NM95@976|Bacteroidetes,47PJI@768503|Cytophagia 976|Bacteroidetes S TIGRFAM channel protein, hemolysin III family hly-III - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII CMS3_k127_5319830_3 153721.MYP_1196 3.478e-109 360.0 COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47KQ3@768503|Cytophagia 976|Bacteroidetes IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB CMS3_k127_5319830_8 1168034.FH5T_09570 1.886e-36 141.0 COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,2FM71@200643|Bacteroidia 976|Bacteroidetes F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin CMS3_k127_5321359_1 880070.Cycma_2100 1.168e-37 150.0 2DNCZ@1|root,32WUS@2|Bacteria,4NUIP@976|Bacteroidetes,47RCB@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5321359_2 929562.Emtol_1942 2.342e-31 126.0 COG0759@1|root,COG0759@2|Bacteria,4NVXJ@976|Bacteroidetes,47RUG@768503|Cytophagia 976|Bacteroidetes S InterPro IPR002696 - - - ko:K08998 - - - - ko00000 - - - Haemolytic CMS3_k127_5321359_0 929562.Emtol_1943 1.976e-43 169.0 COG1729@1|root,COG1729@2|Bacteria,4PMDK@976|Bacteroidetes,47Y26@768503|Cytophagia 976|Bacteroidetes S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - - CMS3_k127_5321359_3 641524.ADICYQ_5071 3.531e-06 57.0 COG0457@1|root,COG0457@2|Bacteria,4NWS5@976|Bacteroidetes,47RWT@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide TPR_1 repeat-containing protein - - - - - - - - - - - - - CMS3_k127_5326160_1 926549.KI421517_gene3175 6.593e-68 239.0 COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5326160_0 1237149.C900_02515 6.012e-148 481.0 COG3250@1|root,COG3250@2|Bacteria,4NE9C@976|Bacteroidetes,47KZT@768503|Cytophagia 976|Bacteroidetes G Horizontally Transferred TransMembrane Domain - - - - - - - - - - - - VKG_Carbox CMS3_k127_5326160_2 1121859.KB890750_gene345 1.075e-12 70.0 COG3489@1|root,COG3489@2|Bacteria,4NFAT@976|Bacteroidetes,47NBA@768503|Cytophagia 976|Bacteroidetes S Imelysin - - - ko:K07338 - - - - ko00000 - - - Peptidase_M75 CMS3_k127_5332217_1 984262.SGRA_3613 1.483e-204 646.0 COG0189@1|root,COG0189@2|Bacteria,4NH5R@976|Bacteroidetes 976|Bacteroidetes HJ ligase activity - - - - - - - - - - - - - CMS3_k127_5332217_3 1122176.KB903543_gene482 1.465e-122 400.0 COG3608@1|root,COG3608@2|Bacteria,4NE8S@976|Bacteroidetes,1IU9G@117747|Sphingobacteriia 976|Bacteroidetes S Succinylglutamate desuccinylase / Aspartoacylase family - - - ko:K06987 - - - - ko00000 - - - AstE_AspA CMS3_k127_5332217_4 56110.Oscil6304_5183 3.045e-98 331.0 COG0189@1|root,COG0189@2|Bacteria,1G4H3@1117|Cyanobacteria,1HFBI@1150|Oscillatoriales 1117|Cyanobacteria HJ Prokaryotic glutathione synthetase, ATP-grasp domain - - 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP CMS3_k127_5332217_5 929556.Solca_3217 8.768e-58 214.0 28JKB@1|root,2Z9D6@2|Bacteria,4NJC1@976|Bacteroidetes,1IRBG@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5332217_2 714943.Mucpa_6461 6.706e-135 436.0 COG0673@1|root,COG0673@2|Bacteria,4NE07@976|Bacteroidetes,1J1A7@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha beta domain gfo_1 - 1.1.1.384 ko:K13327 ko00523,ko01130,map00523,map01130 M00801,M00802 R05526 RC00897 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_5332217_0 1380600.AUYN01000001_gene2638 1.567e-219 685.0 COG1621@1|root,COG3669@1|root,COG1621@2|Bacteria,COG3669@2|Bacteria,4NHRG@976|Bacteroidetes,1HZ4G@117743|Flavobacteriia 976|Bacteroidetes G Alpha-L-fucosidase - - - - - - - - - - - - Alpha_L_fucos,F5_F8_type_C CMS3_k127_5332720_2 1408473.JHXO01000009_gene3299 7.568e-63 225.0 COG3595@1|root,COG3595@2|Bacteria,4NJCC@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - DUF4097 CMS3_k127_5332720_4 1237149.C900_02268 4.309e-26 124.0 COG1404@1|root,COG3291@1|root,COG4733@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NJMC@976|Bacteroidetes,47YSF@768503|Cytophagia 976|Bacteroidetes O PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - - CMS3_k127_5332720_0 338963.Pcar_2713 5.374e-106 355.0 COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,43SCR@69541|Desulfuromonadales 28221|Deltaproteobacteria P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA CMS3_k127_5332720_1 1122176.KB903545_gene894 9.622e-104 344.0 COG0668@1|root,COG0668@2|Bacteria,4NF28@976|Bacteroidetes,1IUR1@117747|Sphingobacteriia 976|Bacteroidetes M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel CMS3_k127_5332720_3 1469557.JSWF01000046_gene146 4.256e-28 128.0 COG2356@1|root,COG3897@1|root,COG4386@1|root,COG4935@1|root,COG2356@2|Bacteria,COG3897@2|Bacteria,COG4386@2|Bacteria,COG4935@2|Bacteria,4PP11@976|Bacteroidetes 976|Bacteroidetes O endonuclease I - - - - - - - - - - - - Cu-binding_MopE,HYR,MAM,P_proprotein,SprB CMS3_k127_5332720_5 649638.Trad_1124 1.188e-15 89.0 COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,1WI48@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Glucose Sorbosone dehydrogenase - - - - - - - - - - - - GSDH,PKD CMS3_k127_5332800_0 929556.Solca_1892 2.478e-117 384.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,1IQYY@117747|Sphingobacteriia 976|Bacteroidetes G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS3_k127_5332800_1 1048983.EL17_19015 4.343e-58 213.0 COG5544@1|root,COG5544@2|Bacteria,4NGNB@976|Bacteroidetes,47JQY@768503|Cytophagia 976|Bacteroidetes S Predicted periplasmic lipoprotein (DUF2279) - - - - - - - - - - - - DUF2279 CMS3_k127_5332800_2 385682.AFSL01000043_gene331 0.0002075 48.0 2C5FT@1|root,33K3C@2|Bacteria,4NZJR@976|Bacteroidetes,2FVX2@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5335427_2 1548153.LR59_10890 6.653e-27 121.0 COG1215@1|root,COG1215@2|Bacteria,1R5JQ@1224|Proteobacteria,43BVH@68525|delta/epsilon subdivisions,2YMCH@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M hmm pf00535 pglI GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046527,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.293 ko:K17250 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 CMS3_k127_5335427_1 143224.JQMD01000002_gene3412 8.331e-94 321.0 COG0438@1|root,COG0438@2|Bacteria,4NW2W@976|Bacteroidetes 976|Bacteroidetes M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 CMS3_k127_5335427_0 143224.JQMD01000002_gene3411 2.655e-117 388.0 COG2244@1|root,COG2244@2|Bacteria,4NHJV@976|Bacteroidetes,1I0VC@117743|Flavobacteriia 976|Bacteroidetes S Polysaccharide biosynthesis protein - - - - - - - - - - - - MatE,Polysacc_synt CMS3_k127_5336079_0 1279009.ADICEAN_00917 1.493e-51 198.0 28U2K@1|root,2ZG8R@2|Bacteria,4P880@976|Bacteroidetes,47WSS@768503|Cytophagia 976|Bacteroidetes S O-Antigen ligase - - - - - - - - - - - - Wzy_C CMS3_k127_5336079_1 380358.XALC_2410 5.318e-10 65.0 COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,1QXVA@1224|Proteobacteria,1T483@1236|Gammaproteobacteria,1X8K2@135614|Xanthomonadales 135614|Xanthomonadales DZ IPT/TIG domain - - - - - - - - - - - - RHS_repeat,TIG CMS3_k127_5336079_2 1121939.L861_16505 1.21e-09 70.0 2FKHX@1|root,34C53@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_5340759_1 1121904.ARBP01000012_gene1259 3.857e-20 106.0 28I1Q@1|root,2Z869@2|Bacteria,4NH2E@976|Bacteroidetes,47M2D@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5340759_0 1121875.KB907546_gene2490 2.786e-65 233.0 COG2264@1|root,COG2264@2|Bacteria,4NFRW@976|Bacteroidetes,1HXXE@117743|Flavobacteriia 976|Bacteroidetes J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA CMS3_k127_5349806_2 639030.JHVA01000001_gene600 1.815e-53 197.0 COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria,2JI6U@204432|Acidobacteriia 204432|Acidobacteriia IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_5349806_0 1121904.ARBP01000009_gene4357 4.869e-312 987.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47JYA@768503|Cytophagia 2|Bacteria C Planctomycete cytochrome C - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 CMS3_k127_5349806_1 1121904.ARBP01000009_gene4358 3.233e-248 773.0 COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,47KYW@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_5351273_5 1122176.KB903531_gene2762 6.163e-26 124.0 COG1572@1|root,COG4447@1|root,COG1572@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Laminin_G_3,TM_helix CMS3_k127_5351273_0 1121904.ARBP01000002_gene7088 2.178e-114 393.0 COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,47MU2@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_5351273_1 1121904.ARBP01000002_gene7087 2.427e-108 370.0 COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47MD4@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 CMS3_k127_5351273_3 317936.Nos7107_3404 4.026e-35 145.0 COG1216@1|root,COG1216@2|Bacteria,1G09N@1117|Cyanobacteria,1HSNK@1161|Nostocales 1117|Cyanobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_5351273_4 933115.GPDM_07085 6.853e-33 139.0 COG1216@1|root,COG1216@2|Bacteria,1V7WV@1239|Firmicutes,4HJ3H@91061|Bacilli,26IG4@186818|Planococcaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_5351273_2 1185876.BN8_02616 4.374e-44 177.0 2BWGY@1|root,3486E@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_5351273_6 1163409.UUA_02821 1.778e-05 53.0 COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,1X5U2@135614|Xanthomonadales 135614|Xanthomonadales S Membrane protein involved in the export of O-antigen and teichoic acid gumJ - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C CMS3_k127_5365419_4 1121904.ARBP01000062_gene1618 3.628e-21 95.0 COG0457@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - HTH_18,TPR_8 CMS3_k127_5365419_2 143224.JQMD01000002_gene1606 3.866e-189 605.0 COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1HWTC@117743|Flavobacteriia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_5365419_0 1185876.BN8_01204 1.826e-306 959.0 COG0578@1|root,COG0578@2|Bacteria,4PNA7@976|Bacteroidetes,47NR8@768503|Cytophagia 976|Bacteroidetes C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored CMS3_k127_5365419_3 1121904.ARBP01000012_gene1244 7.617e-65 235.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5365419_1 1313421.JHBV01000012_gene4088 7.11e-195 625.0 COG0644@1|root,COG0644@2|Bacteria 2|Bacteria C geranylgeranyl reductase activity - - - - - - - - - - - - FAD_binding_3,Lycopene_cycl,Trp_halogenase CMS3_k127_5379854_3 1121904.ARBP01000022_gene3514 5.321e-35 136.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,47JEI@768503|Cytophagia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_5379854_0 1121904.ARBP01000022_gene3513 0.0 1359.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47K5R@768503|Cytophagia 976|Bacteroidetes P TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5379854_2 1349822.NSB1T_10185 5.701e-46 180.0 COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,2FMMP@200643|Bacteroidia,22WMS@171551|Porphyromonadaceae 976|Bacteroidetes M peptidase S41 - - - - - - - - - - - - Peptidase_S41,Tricorn_C1 CMS3_k127_5379854_1 760192.Halhy_2607 7.498e-53 191.0 COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1IZDH@117747|Sphingobacteriia 976|Bacteroidetes I PFAM Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS3_k127_5380529_1 1121904.ARBP01000001_gene5545 2.258e-108 355.0 COG1136@1|root,COG1136@2|Bacteria,4NEC5@976|Bacteroidetes,47N33@768503|Cytophagia 976|Bacteroidetes V ABC transporter - - - - - - - - - - - - ABC_tran CMS3_k127_5380529_0 313596.RB2501_12642 6.699e-225 704.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1HWVS@117743|Flavobacteriia 976|Bacteroidetes C Dihydrolipoyl dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim CMS3_k127_5380529_2 1519464.HY22_05725 5.119e-106 364.0 COG0497@1|root,COG0497@2|Bacteria,1FDSV@1090|Chlorobi 1090|Chlorobi L May be involved in recombinational repair of damaged DNA - - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N CMS3_k127_5380529_3 153721.MYP_1067 3.173e-62 220.0 COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia 976|Bacteroidetes O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K01802,ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase CMS3_k127_5381144_1 760192.Halhy_3588 7.677e-25 104.0 COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia 976|Bacteroidetes E COG0308 Aminopeptidase N - - - - - - - - - - - - Peptidase_M1 CMS3_k127_5381144_5 643867.Ftrac_3781 1.54e-11 64.0 2DIAB@1|root,302ID@2|Bacteria,4P6WW@976|Bacteroidetes,47WND@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5381144_4 643867.Ftrac_3781 1.275e-20 92.0 2DIAB@1|root,302ID@2|Bacteria,4P6WW@976|Bacteroidetes,47WND@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5381144_2 643867.Ftrac_3780 1.217e-23 103.0 2EIHU@1|root,33C96@2|Bacteria,4NY5F@976|Bacteroidetes,47SZZ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2442) - - - - - - - - - - - - DUF2442 CMS3_k127_5381144_3 1122176.KB903591_gene4777 1.33e-22 98.0 COG2886@1|root,COG2886@2|Bacteria,4NYD2@976|Bacteroidetes 976|Bacteroidetes S Uncharacterised protein family (UPF0175) - - - - - - - - - - - - UPF0175 CMS3_k127_5381144_0 1282876.BAOK01000001_gene3536 2.358e-126 422.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,4BPMV@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Glucose / Sorbosone dehydrogenase yliI - 1.1.5.2 ko:K00117,ko:K21430 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,GSDH CMS3_k127_5387757_0 760192.Halhy_2051 6.126e-231 737.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria 2|Bacteria T PhoQ Sensor - - 4.6.1.1 ko:K01768,ko:K16923,ko:K19694 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00582,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 3.A.1.28 - - 7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_5387757_1 1250232.JQNJ01000001_gene1913 3.379e-151 491.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia 976|Bacteroidetes Q COG1228 Imidazolonepropionase and related - - - - - - - - - - - - Amidohydro_1 CMS3_k127_5388251_0 1123057.P872_23505 1.196e-199 623.0 COG0673@1|root,COG0673@2|Bacteria,4NG5E@976|Bacteroidetes,47NZU@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_5388251_1 760192.Halhy_4904 2.793e-149 479.0 COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes 976|Bacteroidetes S Belongs to the pirin family - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C CMS3_k127_5388251_2 1211035.CD30_15965 4.962e-33 137.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3IX2Q@400634|Lysinibacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family - - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh CMS3_k127_5400908_2 1121904.ARBP01000013_gene291 1.777e-21 101.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47Y22@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_5400908_1 1121904.ARBP01000052_gene3642 2.561e-143 465.0 COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,47VIA@768503|Cytophagia 976|Bacteroidetes E Porphyromonas-type peptidyl-arginine deiminase - - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph CMS3_k127_5400908_0 1239962.C943_01963 7.469e-185 594.0 COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,47KS8@768503|Cytophagia 976|Bacteroidetes EH TIGRFAM acetolactate synthase, large subunit, biosynthetic type - - 2.2.1.6,4.1.1.7 ko:K01576,ko:K01652 ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648 RC00027,RC00106,RC00595,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS3_k127_5400908_3 471854.Dfer_3347 4.037e-13 76.0 COG2374@1|root,COG2374@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - CARDB,Gram_pos_anchor,LTD,SLH CMS3_k127_5401096_1 1121875.KB907550_gene801 2.447e-83 285.0 COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1HYXI@117743|Flavobacteriia 976|Bacteroidetes H Aldolase/RraA - - - - - - - - - - - - RraA-like CMS3_k127_5401096_3 1120919.AUBI01000003_gene1519 1.334e-11 74.0 COG3916@1|root,COG3916@2|Bacteria 2|Bacteria QT Acyl-homoserine-lactone synthase - - - - - - - - - - - - AIRS,AIRS_C,Acetyltransf_1,Acetyltransf_10,Aminotran_5 CMS3_k127_5401096_0 616991.JPOO01000001_gene2842 2.984e-181 574.0 COG1621@1|root,COG3669@1|root,COG1621@2|Bacteria,COG3669@2|Bacteria,4NHRG@976|Bacteroidetes,1HZ4G@117743|Flavobacteriia 976|Bacteroidetes G Alpha-L-fucosidase - - - - - - - - - - - - Alpha_L_fucos,F5_F8_type_C CMS3_k127_5436812_2 313606.M23134_00219 1.183e-76 263.0 COG2972@1|root,COG2972@2|Bacteria,4NH1Q@976|Bacteroidetes,47PMI@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase CMS3_k127_5436812_1 313606.M23134_00218 1.889e-102 338.0 COG3279@1|root,COG3279@2|Bacteria,4NI3K@976|Bacteroidetes,47PDV@768503|Cytophagia 976|Bacteroidetes T LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg CMS3_k127_5436812_0 153721.MYP_2359 2.089e-196 618.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,47KP9@768503|Cytophagia 976|Bacteroidetes H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 CMS3_k127_5436812_4 929556.Solca_1842 1.65e-33 137.0 COG0224@1|root,COG0224@2|Bacteria,4NM5H@976|Bacteroidetes,1IRVY@117747|Sphingobacteriia 976|Bacteroidetes C WbqC-like protein family - - - - - - - - - - - - WbqC CMS3_k127_5437110_2 760192.Halhy_1534 1.908e-211 664.0 COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,1IQDI@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_5437110_0 760192.Halhy_1533 4.848e-276 863.0 COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,1IR1M@117747|Sphingobacteriia 976|Bacteroidetes S Methane oxygenase PmoA - - - - - - - - - - - - PmoA CMS3_k127_5437110_1 1185876.BN8_04073 2.226e-248 803.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47M35@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5438061_2 1166018.FAES_1173 1.022e-42 161.0 COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia 976|Bacteroidetes S Rhodanese Homology Domain - - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese CMS3_k127_5438061_0 1123278.KB893387_gene4352 4.491e-146 469.0 COG0709@1|root,COG0709@2|Bacteria,4NI4R@976|Bacteroidetes,47JJA@768503|Cytophagia 976|Bacteroidetes E Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C CMS3_k127_5438061_1 1408422.JHYF01000010_gene3332 3.815e-107 363.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,36DYZ@31979|Clostridiaceae 186801|Clostridia C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K11102 - - - - ko00000,ko02000 2.A.23.1.1,2.A.23.1.2 - - SDF CMS3_k127_5438061_3 313606.M23134_02281 5.989e-31 126.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity - - - - - - - - - - - - His_Phos_1 CMS3_k127_5443767_4 679937.Bcop_0076 2.653e-17 83.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,4AKHT@815|Bacteroidaceae 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins tonB2 - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_5443767_3 929703.KE386491_gene3637 3.465e-26 123.0 COG0810@1|root,COG0810@2|Bacteria,4NFH6@976|Bacteroidetes,47XHB@768503|Cytophagia 976|Bacteroidetes U Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - ko:K03832 - - - - ko00000,ko02000 2.C.1.1 - - TonB_C CMS3_k127_5443767_1 1033802.SSPSH_001224 2.421e-59 214.0 COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Peptidyl-prolyl cis-trans fkpA GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042026,GO:0042597,GO:0044464 5.2.1.8 ko:K01802,ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N CMS3_k127_5443767_0 313606.M23134_04190 3.022e-259 812.0 COG1132@1|root,COG1132@2|Bacteria,4NHI1@976|Bacteroidetes,47JJQ@768503|Cytophagia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CMS3_k127_5443767_2 304371.MCP_0795 6.947e-31 125.0 COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota 28890|Euryarchaeota S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA CMS3_k127_5449064_5 760192.Halhy_4293 8.425e-13 72.0 COG2425@1|root,COG2425@2|Bacteria,4NJ1T@976|Bacteroidetes 976|Bacteroidetes S protein containing a von Willebrand factor type A (vWA) domain - - - - - - - - - - - - VWA_2,VWA_CoxE CMS3_k127_5449064_4 926549.KI421517_gene957 1.184e-77 270.0 COG0697@1|root,COG0697@2|Bacteria,4NGPQ@976|Bacteroidetes,47P5U@768503|Cytophagia 976|Bacteroidetes EG EamA-like transporter family - - - - - - - - - - - - EamA CMS3_k127_5449064_1 1121904.ARBP01000007_gene3097 6.499e-124 406.0 COG3367@1|root,COG3367@2|Bacteria,4NGXN@976|Bacteroidetes,47NP1@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF1611_N) Rossmann-like domain - - - - - - - - - - - - DUF1611,DUF1611_N CMS3_k127_5449064_2 1121904.ARBP01000006_gene4066 7.249e-123 403.0 COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,47N8Q@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_5449064_0 1121904.ARBP01000001_gene5494 7.785e-136 457.0 COG0793@1|root,COG0793@2|Bacteria,4NFK4@976|Bacteroidetes,47KAN@768503|Cytophagia 976|Bacteroidetes M Belongs to the peptidase S41A family - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 CMS3_k127_5449064_3 1279009.ADICEAN_01388 5.291e-85 293.0 28IM1@1|root,2Z8MK@2|Bacteria,4NIZ0@976|Bacteroidetes,47SFS@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5450674_4 1455608.JDTH01000002_gene1957 3.437e-30 127.0 COG0451@1|root,arCOG03018@2157|Archaea,2XWB1@28890|Euryarchaeota,23TGM@183963|Halobacteria 183963|Halobacteria M NAD-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase,NAD_binding_10 CMS3_k127_5450674_0 926562.Oweho_0293 9.042e-115 376.0 COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,1IG05@117743|Flavobacteriia,2PC38@246874|Cryomorphaceae 976|Bacteroidetes S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563,ko:K22318 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS3_k127_5450674_1 1250005.PHEL85_1512 2.192e-76 259.0 COG0664@1|root,COG0664@2|Bacteria,4NMRN@976|Bacteroidetes,1I1F9@117743|Flavobacteriia 976|Bacteroidetes T cyclic nucleotide-binding - - - - - - - - - - - - cNMP_binding CMS3_k127_5450674_2 991.IW20_12095 5.3e-64 223.0 COG3708@1|root,COG3708@2|Bacteria,4NQ46@976|Bacteroidetes,1I45F@117743|Flavobacteriia,2NW6B@237|Flavobacterium 976|Bacteroidetes K transcription activator, effector binding - - - ko:K13653 - - - - ko00000,ko03000 - - - Cass2,GyrI-like CMS3_k127_5450674_3 471854.Dfer_4276 2.528e-48 177.0 COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes 976|Bacteroidetes S Pfam Activator of Hsp90 ATPase - - - - - - - - - - - - 3-dmu-9_3-mt,AHSA1 CMS3_k127_5455591_0 1313421.JHBV01000015_gene5768 8.333e-231 733.0 COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia 976|Bacteroidetes O COG1331 Highly conserved protein containing a thioredoxin domain - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH CMS3_k127_5455591_2 1044.EH31_10350 3.922e-06 59.0 2EB2V@1|root,3353M@2|Bacteria,1QED4@1224|Proteobacteria,2U3RZ@28211|Alphaproteobacteria,2K1M2@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function (DUF4403) - - - - - - - - - - - - DUF4403 CMS3_k127_5455591_1 926549.KI421517_gene1507 8.19e-80 276.0 COG4874@1|root,COG4874@2|Bacteria,4NFG3@976|Bacteroidetes,47KEY@768503|Cytophagia 976|Bacteroidetes S Amidinotransferase - - - - - - - - - - - - Amidinotransf CMS3_k127_5456424_1 1450525.JATV01000005_gene336 4.3e-178 559.0 COG0388@1|root,COG0388@2|Bacteria,4NEME@976|Bacteroidetes,1HY7N@117743|Flavobacteriia,2NV1S@237|Flavobacterium 976|Bacteroidetes S Carbon-nitrogen hydrolase pabB - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase CMS3_k127_5456424_0 1202532.FF52_04005 3.007e-182 574.0 COG2957@1|root,COG2957@2|Bacteria,4NGF8@976|Bacteroidetes,1HYT2@117743|Flavobacteriia,2NV1V@237|Flavobacterium 976|Bacteroidetes E Belongs to the agmatine deiminase family aguA - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph CMS3_k127_5456424_2 1202532.FF52_18123 5.412e-15 77.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1HX27@117743|Flavobacteriia,2NTH3@237|Flavobacterium 976|Bacteroidetes G hydrolase, family 3 - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14 CMS3_k127_5457395_6 1121012.AUKX01000052_gene2581 1.345e-81 294.0 COG1409@1|root,COG1409@2|Bacteria,4NKP0@976|Bacteroidetes,1HY1S@117743|Flavobacteriia,23H8T@178469|Arenibacter 976|Bacteroidetes S Calcineurin-like phosphoesterase - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Metallophos,SASA CMS3_k127_5457395_1 1121011.AUCB01000039_gene945 1.134e-190 613.0 COG1073@1|root,COG1073@2|Bacteria,4PKM0@976|Bacteroidetes,1IJCB@117743|Flavobacteriia 976|Bacteroidetes S alpha beta - - - - - - - - - - - - Lipase_GDSL_2,Peptidase_S9 CMS3_k127_5457395_4 1121011.AUCB01000039_gene951 1.876e-107 349.0 COG1621@1|root,COG1621@2|Bacteria,4NG4M@976|Bacteroidetes,1HZSX@117743|Flavobacteriia 976|Bacteroidetes G Glycosyl hydrolases family 43 - - - - - - - - - - - - Glyco_hydro_43 CMS3_k127_5457395_2 1121875.KB907553_gene24 2.983e-184 607.0 COG0412@1|root,COG1262@1|root,COG2114@1|root,COG0412@2|Bacteria,COG1262@2|Bacteria,COG2114@2|Bacteria,4PPKM@976|Bacteroidetes 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc CMS3_k127_5457395_5 204669.Acid345_1271 8.193e-102 350.0 COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia 204432|Acidobacteriia C TIGRFAM phytoene desaturase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase CMS3_k127_5457395_0 204669.Acid345_1270 1.373e-204 649.0 COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia 204432|Acidobacteriia Q Flavin containing amine oxidoreductase - - - - - - - - - - - - NAD_binding_8 CMS3_k127_5457395_3 204669.Acid345_1269 2.176e-113 378.0 COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C CMS3_k127_5457395_7 1288963.ADIS_2769 8.802e-60 219.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - 3.2.1.18,3.2.1.4 ko:K01179,ko:K01186 ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142 - R04018,R06200,R11307,R11308 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33,GH5,GH9 - BNR_2,BNR_3,CelD_N,Dockerin_1,Glyco_hydro_9,Sortilin-Vps10 CMS3_k127_5461662_2 1288963.ADIS_3270 4.984e-27 117.0 COG3568@1|root,COG3568@2|Bacteria,4PNNN@976|Bacteroidetes,47YCN@768503|Cytophagia 976|Bacteroidetes S Endonuclease Exonuclease Phosphatase - - - - - - - - - - - - - CMS3_k127_5461662_0 1121904.ARBP01000019_gene2730 2.335e-130 421.0 COG0667@1|root,COG0667@2|Bacteria,4NP8D@976|Bacteroidetes 976|Bacteroidetes C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CMS3_k127_5461662_1 1123276.KB893247_gene136 1.352e-61 216.0 COG2133@1|root,COG3291@1|root,COG3828@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,COG4654@2|Bacteria,4NDVK@976|Bacteroidetes,47MAT@768503|Cytophagia 976|Bacteroidetes CG Cytochrome c, class I - - - ko:K08738,ko:K09992 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,Cytochrome_CBB3,GSDH,PKD,ThuA CMS3_k127_5463840_0 886379.AEWI01000066_gene2331 1.266e-84 289.0 COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,2FMQN@200643|Bacteroidia,3XIS8@558415|Marinilabiliaceae 976|Bacteroidetes M Protein of unknown function (DUF3347) - - - ko:K07798 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1 - - DUF3347,HMA,HlyD_D23 CMS3_k127_5463840_2 512565.AMIS_24080 3.462e-17 93.0 COG4249@1|root,COG4249@2|Bacteria,2IAM3@201174|Actinobacteria,4DF6T@85008|Micromonosporales 201174|Actinobacteria S Caspase domain - - - - - - - - - - - - Peptidase_C14,WD40 CMS3_k127_5463840_1 1166018.FAES_0470 2.538e-44 168.0 COG1729@1|root,COG1729@2|Bacteria,4PKMW@976|Bacteroidetes,47JRZ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6,TPR_8 CMS3_k127_5471466_1 926562.Oweho_1277 1.523e-08 64.0 COG4206@1|root,COG4206@2|Bacteria 2|Bacteria H cobalamin-transporting ATPase activity - - - - - - - - - - - - CarbopepD_reg_2,OMP_b-brl_3,Peptidase_M56,Plug,TonB_C,TonB_dep_Rec CMS3_k127_5471466_0 1121288.AULL01000017_gene2409 5.923e-118 399.0 COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,1I9DA@117743|Flavobacteriia 976|Bacteroidetes S TIGRFAM Por secretion system C-terminal sorting domain - - - - - - - - - - - - - CMS3_k127_5477336_1 760192.Halhy_0549 4.069e-110 357.0 28JP4@1|root,2Z9F6@2|Bacteria,4NDYM@976|Bacteroidetes,1IVSV@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5477336_2 477641.MODMU_4191 1.82e-104 357.0 COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4EV6E@85013|Frankiales 201174|Actinobacteria F PFAM amidohydrolase - - 3.5.2.2 ko:K01464 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 M00046 R02269,R03055,R08227 RC00632,RC00680 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Amidohydro_1 CMS3_k127_5477336_0 1449335.JQLG01000004_gene1810 3.341e-115 377.0 COG1028@1|root,COG1028@2|Bacteria 1449335.JQLG01000004_gene1810|- IQ oxidoreductase activity, acting on CH-OH group of donors - - - - - - - - - - - - - CMS3_k127_5483632_0 1121904.ARBP01000001_gene5972 1.175e-253 792.0 COG2721@1|root,COG2721@2|Bacteria,4NFVQ@976|Bacteroidetes,47K7S@768503|Cytophagia 976|Bacteroidetes G PFAM D-galactarate dehydratase Altronate hydrolase uxaA - 4.2.1.7 ko:K01685 ko00040,ko01100,map00040,map01100 M00631 R01540 RC00543 ko00000,ko00001,ko00002,ko01000 - - - GD_AH_C,SAF CMS3_k127_5483632_1 1121289.JHVL01000008_gene1277 8.041e-177 567.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia,36FPY@31979|Clostridiaceae 186801|Clostridia G Belongs to the mannitol dehydrogenase family. UxaB subfamily uxaB - 1.1.1.58 ko:K00041 ko00040,ko01100,map00040,map01100 M00631 R02555 RC00085 ko00000,ko00001,ko00002,ko01000 - - - Mannitol_dh,Mannitol_dh_C CMS3_k127_5483632_2 1123248.KB893338_gene2306 1.154e-105 361.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IRGG@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5487760_0 742817.HMPREF9449_02566 1.02e-63 232.0 COG0628@1|root,COG0628@2|Bacteria,4NFHZ@976|Bacteroidetes 976|Bacteroidetes F permease - - - - - - - - - - - - AI-2E_transport CMS3_k127_5487760_2 1124780.ANNU01000056_gene3483 1.11e-49 183.0 COG1739@1|root,COG1739@2|Bacteria,4NF0D@976|Bacteroidetes,47P9D@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised protein family UPF0029, Impact, N-terminal yigZ - - - - - - - - - - - UPF0029 CMS3_k127_5487760_1 313606.M23134_04372 5.404e-54 195.0 COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,47P7T@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5487760_4 700598.Niako_4546 8.762e-06 55.0 2A95J@1|root,30YA2@2|Bacteria,4NP9E@976|Bacteroidetes,1ITH5@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5487760_3 926562.Oweho_0635 1.083e-24 110.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,2PB9Y@246874|Cryomorphaceae 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_5496355_2 468059.AUHA01000003_gene1546 6.163e-44 164.0 COG0526@1|root,COG0526@2|Bacteria,4PKPR@976|Bacteroidetes,1J0J2@117747|Sphingobacteriia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA CMS3_k127_5496355_3 1178825.ALIH01000020_gene2720 1.29e-35 141.0 COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia 976|Bacteroidetes CO Thioredoxin - - - - - - - - - - - - AhpC-TSA,Thioredoxin CMS3_k127_5496355_1 1168289.AJKI01000026_gene1405 3.235e-58 207.0 COG0526@1|root,COG0526@2|Bacteria,4PKPR@976|Bacteroidetes,2FS08@200643|Bacteroidia,3XK8Q@558415|Marinilabiliaceae 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA CMS3_k127_5496355_4 435591.BDI_0954 1.187e-28 119.0 2CZWI@1|root,32T79@2|Bacteria,4NSNW@976|Bacteroidetes,2FTY4@200643|Bacteroidia,22YDH@171551|Porphyromonadaceae 976|Bacteroidetes S DNA-binding protein - - - - - - - - - - - - - CMS3_k127_5496355_0 1124780.ANNU01000005_gene2412 1.799e-75 276.0 COG1138@1|root,COG1138@2|Bacteria,4NGXI@976|Bacteroidetes,47M2N@768503|Cytophagia 976|Bacteroidetes O PFAM Cytochrome c assembly protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm CMS3_k127_5498016_0 1443665.JACA01000001_gene2557 2.919e-178 599.0 COG3299@1|root,COG3299@2|Bacteria,4NF69@976|Bacteroidetes,1HYP7@117743|Flavobacteriia,2YIDG@290174|Aquimarina 976|Bacteroidetes S homolog of phage Mu protein gp47 - - - - - - - - - - - - Baseplate_J CMS3_k127_5548885_0 1305737.JAFX01000001_gene966 1.514e-113 374.0 COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,47JHP@768503|Cytophagia 976|Bacteroidetes D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge CMS3_k127_5548885_1 1094980.Mpsy_3018 1.271e-07 55.0 COG5513@1|root,arCOG03544@2157|Archaea,2Y0YF@28890|Euryarchaeota,2N9ZK@224756|Methanomicrobia 224756|Methanomicrobia S Chagasin family peptidase inhibitor I42 - - - ko:K14475 ko05143,map05143 - - - ko00000,ko00001 - - - Inhibitor_I42 CMS3_k127_5573512_0 743722.Sph21_2950 3.937e-144 471.0 COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,1IQVI@117747|Sphingobacteriia 976|Bacteroidetes P PFAM RagB SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_5573512_1 313603.FB2170_12191 7.658e-42 160.0 COG1416@1|root,COG1416@2|Bacteria,4NNH1@976|Bacteroidetes,1I2I8@117743|Flavobacteriia,2PHRB@252356|Maribacter 976|Bacteroidetes S DsrE/DsrF-like family - - - - - - - - - - - - DrsE CMS3_k127_5578354_0 153721.MYP_331 8.644e-317 989.0 COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family malZ - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31 CMS3_k127_5578354_2 1124780.ANNU01000051_gene2082 1.991e-43 169.0 COG2971@1|root,COG2971@2|Bacteria,4NEV4@976|Bacteroidetes,47MGQ@768503|Cytophagia 976|Bacteroidetes G N-acetylglucosamine kinase - - - - - - - - - - - - BcrAD_BadFG CMS3_k127_5578354_1 1396141.BATP01000007_gene5717 3.848e-84 293.0 COG1449@1|root,COG1449@2|Bacteria,46XBE@74201|Verrucomicrobia,2IVAX@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 57 - - 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH57 - Glyco_hydro_57 CMS3_k127_5578354_3 1121930.AQXG01000004_gene2941 2.22e-33 130.0 COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1IT31@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase CMS3_k127_5584315_0 1121904.ARBP01000006_gene3679 4.622e-120 391.0 COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,47JVG@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran CMS3_k127_5584315_1 1122179.KB890419_gene102 2.001e-100 344.0 COG2819@1|root,COG2819@2|Bacteria,4PI74@976|Bacteroidetes,1IZ25@117747|Sphingobacteriia 976|Bacteroidetes S Putative esterase - - - ko:K07017 - - - - ko00000 - - - Esterase CMS3_k127_5584315_3 1317122.ATO12_18055 1.482e-62 219.0 COG0317@1|root,COG0317@2|Bacteria,4NNC2@976|Bacteroidetes,1I1UG@117743|Flavobacteriia,2YJC9@290174|Aquimarina 976|Bacteroidetes KT HD domain - - - - - - - - - - - - HD_4 CMS3_k127_5584315_4 880073.Calab_0295 1.389e-24 106.0 COG2827@1|root,COG2827@2|Bacteria 2|Bacteria L Endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS3_k127_5584315_2 1499967.BAYZ01000080_gene938 1.044e-65 234.0 COG5563@1|root,COG5563@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF5122 CMS3_k127_5600828_2 1189612.A33Q_2600 1.574e-13 75.0 28KSE@1|root,2ZBRS@2|Bacteria,4NNCR@976|Bacteroidetes,47P8I@768503|Cytophagia 976|Bacteroidetes S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_5600828_0 1122176.KB903560_gene3555 3.156e-259 818.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPMK@117747|Sphingobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_5600828_1 1296415.JACC01000023_gene4288 1.727e-40 156.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_5616120_1 269798.CHU_2924 2.795e-61 235.0 COG3209@1|root,COG3291@1|root,COG3209@2|Bacteria,COG3291@2|Bacteria,4NGZV@976|Bacteroidetes,47TBR@768503|Cytophagia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,IgGFc_binding,PKD,SprB CMS3_k127_5616120_0 1120968.AUBX01000009_gene738 2.793e-179 571.0 COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,47JZU@768503|Cytophagia 976|Bacteroidetes C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA CMS3_k127_5620369_1 1120968.AUBX01000010_gene1254 3.198e-71 244.0 COG3485@1|root,COG3485@2|Bacteria,4NFYS@976|Bacteroidetes,47KW0@768503|Cytophagia 976|Bacteroidetes Q Dioxygenase - - - - - - - - - - - - Dioxygenase_C CMS3_k127_5620369_0 1484460.JSWG01000009_gene131 1.044e-246 779.0 COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia 976|Bacteroidetes P COG0659 Sulfate permease and related - - - - - - - - - - - - Sulfate_transp CMS3_k127_5621471_0 1168034.FH5T_01730 1.953e-233 730.0 COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia 976|Bacteroidetes E Pyridoxal-dependent decarboxylase, C-terminal sheet domain speA - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CMS3_k127_5621471_1 1121930.AQXG01000003_gene2691 6.117e-176 555.0 COG1899@1|root,COG1899@2|Bacteria,4NEZ0@976|Bacteroidetes,1IPCP@117747|Sphingobacteriia 976|Bacteroidetes O Deoxyhypusine synthase dys1 - 2.5.1.46 ko:K00809 - - - - ko00000,ko01000 - - - DS CMS3_k127_5621471_3 616991.JPOO01000001_gene2984 5.251e-79 267.0 COG2940@1|root,COG2940@2|Bacteria,4NM5I@976|Bacteroidetes,1I1ME@117743|Flavobacteriia,23HVJ@178469|Arenibacter 976|Bacteroidetes S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - - - - - - - - - - SET CMS3_k127_5621471_4 1122927.KB895412_gene1237 6.934e-73 274.0 COG1470@1|root,COG3291@1|root,COG3408@1|root,COG1470@2|Bacteria,COG3291@2|Bacteria,COG3408@2|Bacteria 2|Bacteria G Glycogen debranching enzyme - - - - - - - - - - - - CarboxypepD_reg,DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,Metallophos,NPCBM,NPCBM_assoc,PKD,Sigma70_r2 CMS3_k127_5621471_2 1396141.BATP01000030_gene3687 5.487e-96 344.0 COG2133@1|root,COG3533@1|root,COG3897@1|root,COG2133@2|Bacteria,COG3533@2|Bacteria,COG3897@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae 2|Bacteria G Glucose / Sorbosone dehydrogenase psrP1 - - - - - - - - - - - CBM_6,DUF11,GSDH,Melibiase_2,NHL,SdrD_B CMS3_k127_5622529_2 313606.M23134_02536 7.774e-56 216.0 COG4775@1|root,COG4775@2|Bacteria,4NF35@976|Bacteroidetes,47NVM@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein protective antigen OMA87 - - - - - - - - - - - - Bac_surface_Ag,POTRA,ShlB CMS3_k127_5622529_3 1313421.JHBV01000039_gene2667 1.053e-52 199.0 COG1594@1|root,COG1594@2|Bacteria,4PKAQ@976|Bacteroidetes,1J0UN@117747|Sphingobacteriia 976|Bacteroidetes K Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - - - - - - - - - - - - CMS3_k127_5622529_4 1358423.N180_13270 9.844e-28 122.0 COG0106@1|root,COG0106@2|Bacteria,4NEEX@976|Bacteroidetes,1IW2E@117747|Sphingobacteriia 976|Bacteroidetes E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS3_k127_5622529_1 1453500.AT05_01825 1.152e-63 245.0 COG3291@1|root,COG3291@2|Bacteria,4NICC@976|Bacteroidetes 976|Bacteroidetes S PFAM PKD domain - - - - - - - - - - - - CHU_C,PKD CMS3_k127_5622529_0 1341181.FLJC2902T_02700 1.164e-102 345.0 COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1HXAP@117743|Flavobacteriia,2NTYF@237|Flavobacterium 976|Bacteroidetes L single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS3_k127_5622529_5 1268072.PSAB_11365 2.444e-15 79.0 COG1695@1|root,COG1695@2|Bacteria,1VF68@1239|Firmicutes,4HXG7@91061|Bacilli,26YQ5@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_5622862_5 1121904.ARBP01000012_gene1244 1.154e-25 109.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5622862_1 761193.Runsl_4321 2.325e-107 353.0 COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47NFM@768503|Cytophagia 976|Bacteroidetes I Enoyl-CoA hydratase/isomerase - - 4.2.1.17 ko:K01692,ko:K01715 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_5622862_4 1124780.ANNU01000008_gene2747 1.394e-27 117.0 COG2010@1|root,COG2010@2|Bacteria,4NTWV@976|Bacteroidetes,47REP@768503|Cytophagia 976|Bacteroidetes C Cytochrome c, class I aniA - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS3_k127_5622862_3 1237149.C900_00531 7.631e-54 196.0 COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47NK1@768503|Cytophagia 976|Bacteroidetes S protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC CMS3_k127_5622862_0 1250232.JQNJ01000001_gene1654 3.822e-114 379.0 COG1929@1|root,COG1929@2|Bacteria,4NFK8@976|Bacteroidetes,1HXJ7@117743|Flavobacteriia 976|Bacteroidetes G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase CMS3_k127_5622862_2 1122176.KB903531_gene2990 1.558e-94 327.0 COG4412@1|root,COG4412@2|Bacteria,4PM4A@976|Bacteroidetes,1IWTI@117747|Sphingobacteriia 976|Bacteroidetes UW Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,Peptidase_M36 CMS3_k127_5653712_1 1047013.AQSP01000095_gene2303 1.007e-164 546.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5653712_2 1121904.ARBP01000027_gene714 6.098e-30 122.0 COG1695@1|root,COG1695@2|Bacteria,4NQJP@976|Bacteroidetes,47QWB@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_5653712_0 1313421.JHBV01000011_gene4048 0.0 1024.0 COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,4NI68@976|Bacteroidetes,1IV6E@117747|Sphingobacteriia 976|Bacteroidetes CI MaoC like domain paaN - 1.2.1.91,3.3.2.12 ko:K02618 ko00360,ko01120,map00360,map01120 - R09820,R09836 RC00080,RC02667 ko00000,ko00001,ko01000 - - - Aldedh,DUF1569,MaoC_dehydratas CMS3_k127_5653712_3 1122176.KB903539_gene1383 1.321e-26 111.0 COG1024@1|root,COG1024@2|Bacteria,4NEH4@976|Bacteroidetes,1IRSU@117747|Sphingobacteriia 976|Bacteroidetes I COG1024 Enoyl-CoA hydratase carnithine racemase - - 4.2.1.18 ko:K13766 ko00280,ko01100,map00280,map01100 M00036 R02085 RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS3_k127_5653874_1 984262.SGRA_2554 6.151e-50 189.0 COG2885@1|root,COG2885@2|Bacteria,4PNPK@976|Bacteroidetes 976|Bacteroidetes M Pfam:DUF3308 - - - - - - - - - - - - PorP_SprF CMS3_k127_5653874_0 1121889.AUDM01000015_gene2014 2.384e-159 518.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia,2NSWF@237|Flavobacterium 976|Bacteroidetes M Membrane bound O-acyl transferase, MBOAT family protein algI - - - - - - - - - - - MBOAT CMS3_k127_5653874_2 880071.Fleli_1914 1.296e-39 162.0 COG2755@1|root,COG2755@2|Bacteria,4NGW6@976|Bacteroidetes,47P2X@768503|Cytophagia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2,LysM CMS3_k127_5654372_2 1122179.KB890416_gene2659 1.063e-41 161.0 COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1J0TE@117747|Sphingobacteriia 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain qseC - - - - - - - - - - - HATPase_c,HisKA CMS3_k127_5654372_1 1122179.KB890416_gene2660 4.863e-90 302.0 COG0745@1|root,COG0745@2|Bacteria,4NGVV@976|Bacteroidetes,1IPYW@117747|Sphingobacteriia 976|Bacteroidetes K Response regulator receiver domain - - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_5654372_3 247490.KSU1_B0331 1.39e-26 124.0 COG3746@1|root,COG3746@2|Bacteria,2J0N7@203682|Planctomycetes 203682|Planctomycetes P phosphate-selective porin O and P - - - - - - - - - - - - Porin_O_P CMS3_k127_5654372_0 1123024.AUII01000006_gene4636 1.07e-317 992.0 COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4EE9U@85010|Pseudonocardiales 201174|Actinobacteria P AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran CMS3_k127_5656421_0 945713.IALB_0193 3.46e-125 414.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,PD40,Peptidase_M14,Peptidase_S9 CMS3_k127_5656421_1 1408433.JHXV01000021_gene1702 2.694e-80 281.0 COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes,1ICP7@117743|Flavobacteriia,2PBGK@246874|Cryomorphaceae 976|Bacteroidetes M Transglycosylase SLT domain - - - - - - - - - - - - SLT CMS3_k127_5656421_2 1121904.ARBP01000006_gene3769 6.398e-42 156.0 COG0741@1|root,COG0741@2|Bacteria,4P2CQ@976|Bacteroidetes 976|Bacteroidetes M Transglycosylase SLT domain - - - - - - - - - - - - SLT CMS3_k127_5660005_1 1123278.KB893389_gene4212 3.957e-117 382.0 COG0777@1|root,COG0777@2|Bacteria,4NFMH@976|Bacteroidetes,47JX2@768503|Cytophagia 976|Bacteroidetes I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS3_k127_5660005_4 1121930.AQXG01000001_gene1271 1.402e-44 163.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1ISZS@117747|Sphingobacteriia 976|Bacteroidetes O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CMS3_k127_5660005_0 313606.M23134_06826 1.145e-236 747.0 COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,47MV2@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_5660005_2 1120965.AUBV01000003_gene419 1.449e-109 359.0 2ACD4@1|root,311YD@2|Bacteria,4NPIQ@976|Bacteroidetes,47UU4@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5660005_3 761193.Runsl_4030 4.6e-81 276.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity yhhY GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.1.2.9 ko:K00604,ko:K03825 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 CMS3_k127_5660005_5 926562.Oweho_1555 8.455e-07 51.0 COG0389@1|root,COG0389@2|Bacteria,4NF1Y@976|Bacteroidetes,1HXHJ@117743|Flavobacteriia,2PAAE@246874|Cryomorphaceae 976|Bacteroidetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH CMS3_k127_5669955_0 869213.JCM21142_41395 1.132e-228 716.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system - - - - - - - - - - - - FeoA,FeoB_C,FeoB_N,Gate CMS3_k127_5669955_3 869213.JCM21142_41394 1.092e-119 389.0 COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,47JEQ@768503|Cytophagia 976|Bacteroidetes P transporter of a GTP-driven Fe(2 ) uptake system - - - - - - - - - - - - FeoA,FeoB_C,FeoB_N,Gate CMS3_k127_5669955_2 869213.JCM21142_41393 1.768e-122 401.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,4NGUP@976|Bacteroidetes 976|Bacteroidetes K iron dependent repressor - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,FeoA CMS3_k127_5669955_1 1048983.EL17_06380 9.941e-124 404.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,47Y6D@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_5672420_1 1313421.JHBV01000011_gene4046 3.986e-103 337.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1IVK0@117747|Sphingobacteriia 976|Bacteroidetes I Belongs to the thiolase family - - - - - - - - - - - - Thiolase_C,Thiolase_N CMS3_k127_5672420_3 1123276.KB893290_gene5205 4.525e-48 190.0 COG1577@1|root,COG1874@1|root,COG2374@1|root,COG2706@1|root,COG4625@1|root,COG4886@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG2374@2|Bacteria,COG2706@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,4NI5S@976|Bacteroidetes,47THH@768503|Cytophagia 976|Bacteroidetes G Dystroglycan-type cadherin-like domains. - - - ko:K07004 - - - - ko00000 - - - Big_5,Calx-beta,Exo_endo_phos,He_PIG,LTD,VCBS CMS3_k127_5672420_0 313603.FB2170_04140 8.83e-251 782.0 COG1858@1|root,COG1858@2|Bacteria,4NJ4X@976|Bacteroidetes,1I05W@117743|Flavobacteriia 976|Bacteroidetes P cytochrome C peroxidase - - - - - - - - - - - - - CMS3_k127_5672420_4 234267.Acid_0687 6.889e-13 74.0 COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria 2|Bacteria S Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_2 CMS3_k127_5672420_2 1242864.D187_007066 1.287e-55 199.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria 1224|Proteobacteria S Metal-dependent hydrolase - - - - - - - - - - - - Cyclase CMS3_k127_5689800_6 1121904.ARBP01000008_gene3239 1.535e-20 94.0 COG5492@1|root,COG5492@2|Bacteria,4NHMV@976|Bacteroidetes,47M4F@768503|Cytophagia 976|Bacteroidetes N Polysaccharide lyase family 8, super-sandwich domain - - 4.2.2.5 ko:K19049 - - - - ko00000,ko01000 - PL8 - Lyase_8,Lyase_8_C,Lyase_8_N CMS3_k127_5689800_4 1242864.D187_002907 1.018e-52 198.0 COG3239@1|root,COG3239@2|Bacteria,1R3Y2@1224|Proteobacteria,434KY@68525|delta/epsilon subdivisions,2WYYD@28221|Deltaproteobacteria,2Z0X8@29|Myxococcales 28221|Deltaproteobacteria I Fatty acid desaturase - - - - - - - - - - - - FA_desaturase CMS3_k127_5689800_5 1122176.KB903598_gene4627 1.119e-33 143.0 2BWJ3@1|root,2Z7IQ@2|Bacteria,4PKVA@976|Bacteroidetes 976|Bacteroidetes S Sulfotransferase family - - - - - - - - - - - - Sulfotransfer_3 CMS3_k127_5689800_1 1123248.KB893359_gene1998 0.0 1241.0 COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,1IR0K@117747|Sphingobacteriia 976|Bacteroidetes G beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - 3.2.1.45 ko:K17108 ko00511,ko00600,ko01100,map00511,map00600,map01100 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH116 - DUF608,Glyco_hydr_116N CMS3_k127_5689800_2 616991.JPOO01000003_gene1312 2.92e-77 269.0 COG3291@1|root,COG3291@2|Bacteria,4NNCK@976|Bacteroidetes,1I6QD@117743|Flavobacteriia,23G1N@178469|Arenibacter 976|Bacteroidetes S PKD domain - - - - - - - - - - - - CBM_4_9,PKD CMS3_k127_5689800_0 1121904.ARBP01000018_gene2699 0.0 1334.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47M5Q@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5689800_3 1434325.AZQN01000008_gene2954 2.435e-67 235.0 COG0521@1|root,COG0521@2|Bacteria,4PKID@976|Bacteroidetes,47MQ9@768503|Cytophagia 976|Bacteroidetes H Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 CMS3_k127_5715949_1 1288963.ADIS_0327 2.092e-62 220.0 2CD2X@1|root,2Z7RW@2|Bacteria,4NI6Q@976|Bacteroidetes,47M77@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5715949_2 1122225.AULQ01000002_gene646 1.453e-51 190.0 COG2197@1|root,COG2197@2|Bacteria,4NQVA@976|Bacteroidetes,1I31H@117743|Flavobacteriia 976|Bacteroidetes K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg CMS3_k127_5715949_0 1122225.AULQ01000002_gene645 1.344e-99 351.0 COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3,TPR_12,TPR_8 CMS3_k127_5717562_2 1121895.Q765_10245 7.79e-64 221.0 COG2342@1|root,COG2342@2|Bacteria,4NH17@976|Bacteroidetes,1I03F@117743|Flavobacteriia,2NTJ1@237|Flavobacterium 976|Bacteroidetes G Glycoside-hydrolase family GH114 - - 6.1.1.16 ko:K01884 ko00970,map00970 M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Glyco_hydro_114 CMS3_k127_5717562_0 153721.MYP_1454 3.039e-173 547.0 COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,47K22@768503|Cytophagia 976|Bacteroidetes H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM CMS3_k127_5717562_1 313606.M23134_00625 8.124e-110 367.0 COG0156@1|root,COG0156@2|Bacteria,4NEXI@976|Bacteroidetes,47MTG@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II bioF - 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_5717562_3 760192.Halhy_5228 9.085e-18 84.0 COG0132@1|root,COG0132@2|Bacteria,4NGKI@976|Bacteroidetes,1IS5T@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 CMS3_k127_5740975_2 694427.Palpr_0469 7.059e-24 103.0 COG1284@1|root,COG1284@2|Bacteria,4NG9F@976|Bacteroidetes,2FS6Q@200643|Bacteroidia,22XWC@171551|Porphyromonadaceae 976|Bacteroidetes S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane CMS3_k127_5740975_0 468059.AUHA01000004_gene2106 9.921e-68 232.0 COG0454@1|root,COG0456@2|Bacteria,4NQ7Z@976|Bacteroidetes,1ISWS@117747|Sphingobacteriia 976|Bacteroidetes K Acetyltransferase, gnat family - - - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 CMS3_k127_5740975_3 1313304.CALK_1985 6.646e-09 60.0 COG1228@1|root,COG1228@2|Bacteria 2|Bacteria Q imidazolonepropionase activity - - - - - - - - - - - - Amidohydro_1 CMS3_k127_5740975_1 1296416.JACB01000018_gene5290 5.266e-67 233.0 COG4430@1|root,COG4430@2|Bacteria,4NKNI@976|Bacteroidetes,1I11I@117743|Flavobacteriia,2YI5V@290174|Aquimarina 976|Bacteroidetes S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - DUF1801,OmdA CMS3_k127_5742106_0 1121904.ARBP01000009_gene4392 6.031e-204 641.0 COG0733@1|root,COG0733@2|Bacteria,4P0HG@976|Bacteroidetes,47XNW@768503|Cytophagia 976|Bacteroidetes S Sodium:neurotransmitter symporter family - - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF CMS3_k127_5742106_1 760192.Halhy_2134 1.916e-169 542.0 COG1228@1|root,COG1228@2|Bacteria,4NFI3@976|Bacteroidetes,1IWRU@117747|Sphingobacteriia 976|Bacteroidetes Q COGs COG1228 Imidazolonepropionase and related amidohydrolase - - - - - - - - - - - - Amidohydro_1 CMS3_k127_5742106_4 927658.AJUM01000019_gene2661 4.6e-42 163.0 COG4849@1|root,COG4849@2|Bacteria,4NMEZ@976|Bacteroidetes,2FSFR@200643|Bacteroidia 976|Bacteroidetes S Protein conserved in bacteria - - - - - - - - - - - - AbiEii CMS3_k127_5742106_3 983548.Krodi_2313 1.18e-55 199.0 28W7P@1|root,2ZI89@2|Bacteria,4NQSV@976|Bacteroidetes,1I2KD@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5742106_2 1317122.ATO12_18215 2.614e-99 330.0 COG1028@1|root,COG1028@2|Bacteria,4NICN@976|Bacteroidetes,1HY8Z@117743|Flavobacteriia,2YIXZ@290174|Aquimarina 976|Bacteroidetes IQ NAD(P)H-binding - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_5744705_1 1121904.ARBP01000009_gene4340 1.881e-126 412.0 COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4PNA4@976|Bacteroidetes,47YAQ@768503|Cytophagia 976|Bacteroidetes CG Glucose / Sorbosone dehydrogenase - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,GSDH,PKD,ThuA CMS3_k127_5744705_3 494419.ALPM01000056_gene2947 5.525e-09 67.0 COG4978@1|root,COG4978@2|Bacteria,2IS9W@201174|Actinobacteria,1W9YZ@1268|Micrococcaceae 201174|Actinobacteria KT Bacterial transcription activator, effector binding domain - - - ko:K13652 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 CMS3_k127_5744705_2 946077.W5A_10799 4.445e-37 153.0 COG1670@1|root,COG1670@2|Bacteria,4NNBE@976|Bacteroidetes,1I22F@117743|Flavobacteriia 976|Bacteroidetes J Polyketide cyclase - - - - - - - - - - - - Polyketide_cyc2 CMS3_k127_5744705_0 1296416.JACB01000013_gene4380 3.497e-160 512.0 COG0436@1|root,COG0436@2|Bacteria,4NSBB@976|Bacteroidetes,1IM6I@117743|Flavobacteriia,2YHQE@290174|Aquimarina 976|Bacteroidetes E Beta-eliminating lyase - - - - - - - - - - - - Aminotran_1_2 CMS3_k127_5749302_2 1121875.KB907550_gene910 2.862e-140 449.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,1HX6C@117743|Flavobacteriia 976|Bacteroidetes H Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CMS3_k127_5749302_0 344747.PM8797T_29842 2.697e-188 608.0 COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes 203682|Planctomycetes S Acetyl xylan esterase (AXE1) - - - - - - - - - - - - AXE1 CMS3_k127_5749302_5 1178825.ALIH01000007_gene1710 1.011e-66 231.0 COG0346@1|root,COG0346@2|Bacteria,4NN6H@976|Bacteroidetes,1I2IV@117743|Flavobacteriia 976|Bacteroidetes E Glyoxalase-like domain - - - ko:K07032 - - - - ko00000 - - - Glyoxalase CMS3_k127_5749302_7 1286632.P278_00790 2.471e-30 123.0 COG3070@1|root,COG3070@2|Bacteria,4NSGZ@976|Bacteroidetes,1I4CE@117743|Flavobacteriia 976|Bacteroidetes K TfoX N-terminal domain - - - - - - - - - - - - TfoX_N CMS3_k127_5749302_4 1121887.AUDK01000014_gene2441 4.904e-75 260.0 COG0300@1|root,COG0300@2|Bacteria,4NKNE@976|Bacteroidetes,1IMIN@117743|Flavobacteriia,2NTWH@237|Flavobacterium 976|Bacteroidetes S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short CMS3_k127_5749302_1 1121904.ARBP01000004_gene799 5.39e-185 591.0 COG3211@1|root,COG3211@2|Bacteria,4NKFU@976|Bacteroidetes,47P4I@768503|Cytophagia 976|Bacteroidetes S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - DUF839 CMS3_k127_5749302_6 1191523.MROS_0796 3.633e-51 184.0 COG3439@1|root,COG3439@2|Bacteria 2|Bacteria D Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 CMS3_k127_5749302_3 641524.ADICYQ_2511 5.72e-114 374.0 2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Collagen_bind_2 CMS3_k127_5751130_2 926556.Echvi_0788 6.222e-93 312.0 COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,47MZ4@768503|Cytophagia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 CMS3_k127_5751130_1 468059.AUHA01000002_gene563 1.376e-117 404.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia 976|Bacteroidetes K Tetratricopeptide repeat - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_5751130_0 1124780.ANNU01000005_gene2472 2.875e-151 484.0 COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,47M82@768503|Cytophagia 976|Bacteroidetes L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N CMS3_k127_5751130_6 1346330.M472_01765 3.269e-16 88.0 2BBPA@1|root,3257C@2|Bacteria,4NRAR@976|Bacteroidetes,1IU32@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF3575) - - - - - - - - - - - - DUF3575 CMS3_k127_5751130_4 313628.LNTAR_08001 7.677e-74 258.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - - CMS3_k127_5751130_5 1121904.ARBP01000004_gene1089 3.442e-29 126.0 2DBXN@1|root,2ZBQR@2|Bacteria,4NN54@976|Bacteroidetes,47PK0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5751130_3 861299.J421_5841 4.456e-77 274.0 COG4198@1|root,COG4198@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF1015,SusD-like_2 CMS3_k127_5751687_3 1237149.C900_05018 1.992e-49 178.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - AraC_binding,Cupin_2,Cupin_7,DUF4440,HTH_18 CMS3_k127_5751687_1 1237149.C900_05017 3.992e-103 342.0 COG2207@1|root,COG2207@2|Bacteria,4NHA5@976|Bacteroidetes,47Y9A@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 CMS3_k127_5751687_2 926549.KI421517_gene3572 1.142e-94 329.0 COG0739@1|root,COG0739@2|Bacteria,4NEBZ@976|Bacteroidetes,47JJ1@768503|Cytophagia 976|Bacteroidetes M Peptidase family M23 - - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23,SH3_3,SH3_4 CMS3_k127_5751687_0 1122176.KB903544_gene740 9.24e-117 381.0 COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,4NDU2@976|Bacteroidetes,1IX7D@117747|Sphingobacteriia 976|Bacteroidetes ET Amino acid permease - - - - - - - - - - - - AA_permease,AA_permease_2,PTS_EIIA_2,TrkA_C CMS3_k127_5757858_2 1121447.JONL01000001_gene788 8.418e-10 59.0 COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CS7@68525|delta/epsilon subdivisions,2X7ZW@28221|Deltaproteobacteria,2MHC1@213115|Desulfovibrionales 28221|Deltaproteobacteria T histidine kinase HAMP region domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg,SBP_bac_3,sCache_3_2 CMS3_k127_5757858_0 506534.Rhein_0855 2.61e-60 224.0 COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,1S1NB@1236|Gammaproteobacteria,1X1T0@135613|Chromatiales 135613|Chromatiales V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_5760163_2 929556.Solca_3900 1.614e-51 193.0 COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1IQW1@117747|Sphingobacteriia 976|Bacteroidetes S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 CMS3_k127_5760163_3 509635.N824_11340 1.04e-31 136.0 COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,1ITS1@117747|Sphingobacteriia 976|Bacteroidetes S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CMS3_k127_5760163_1 1089547.KB913013_gene213 2.142e-146 471.0 COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,47JGV@768503|Cytophagia 976|Bacteroidetes J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - - - - - - - - - - Dus CMS3_k127_5760163_0 1233951.IO90_14180 2.105e-163 532.0 COG0326@1|root,COG0326@2|Bacteria,4PKTZ@976|Bacteroidetes 976|Bacteroidetes O Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c_3 CMS3_k127_5761894_1 1353276.JADR01000006_gene1180 8.888e-31 122.0 COG2367@1|root,COG2367@2|Bacteria,4NHF9@976|Bacteroidetes,1HZHM@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase2 CMS3_k127_5761894_0 1348583.ATLH01000013_gene2762 1.161e-216 702.0 COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia,1FA5V@104264|Cellulophaga 976|Bacteroidetes C TLC ATP/ADP transporter - - - ko:K03301 - - - - ko00000 2.A.12 - - TLC,cNMP_binding CMS3_k127_576431_3 313606.M23134_01610 4.463e-07 52.0 COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes,47TGY@768503|Cytophagia 976|Bacteroidetes M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_576431_2 1121904.ARBP01000005_gene4870 9.638e-111 364.0 COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,47MQ8@768503|Cytophagia 976|Bacteroidetes S Creatinine amidohydrolase crnA - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase CMS3_k127_576431_1 1121904.ARBP01000016_gene5280 5.426e-187 589.0 COG0075@1|root,COG0075@2|Bacteria,4NH61@976|Bacteroidetes,47VRP@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K03430 ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R04152 RC00006,RC00008,RC00018,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CMS3_k127_576431_0 1121904.ARBP01000016_gene5279 0.0 1280.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,4NEK3@976|Bacteroidetes,47JNC@768503|Cytophagia 976|Bacteroidetes C FAD linked oxidases, C-terminal domain - - - - - - - - - - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8 CMS3_k127_5767255_1 1144313.PMI10_03370 2.737e-20 99.0 2AEZV@1|root,314XY@2|Bacteria,4PJ65@976|Bacteroidetes,1IN8X@117743|Flavobacteriia,2NYJB@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5767255_0 760192.Halhy_5102 2.954e-54 201.0 COG3011@1|root,COG3011@2|Bacteria,4NP4T@976|Bacteroidetes,1IXPR@117747|Sphingobacteriia 976|Bacteroidetes S HTTM domain protein - - - - - - - - - - - - VKG_Carbox CMS3_k127_5776148_0 1237149.C900_02591 1.441e-210 680.0 COG0577@1|root,COG0577@2|Bacteria,4NKYD@976|Bacteroidetes,47MU6@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_5783229_11 667632.KB890182_gene921 3.151e-14 74.0 COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,1K1Q3@119060|Burkholderiaceae 28216|Betaproteobacteria D TIGRFAM cell shape determining protein, MreB Mrl family - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl CMS3_k127_5783229_2 641526.ADIWIN_3918 1.252e-138 449.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,1I09H@117743|Flavobacteriia 976|Bacteroidetes G Phosphofructokinase pfp - 2.7.1.11,2.7.1.90 ko:K00895,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK CMS3_k127_5783229_10 1506583.JQJY01000009_gene1119 7.758e-26 113.0 COG3831@1|root,COG3831@2|Bacteria,4NKKF@976|Bacteroidetes,1I0N8@117743|Flavobacteriia,2NT3I@237|Flavobacterium 976|Bacteroidetes S Protein of unknown function (DUF4240) - - - - - - - - - - - - DUF4240 CMS3_k127_5783229_4 1121904.ARBP01000003_gene6435 2.957e-123 412.0 COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,47K1Y@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 CMS3_k127_5783229_0 1124780.ANNU01000042_gene619 7.362e-167 539.0 COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_5783229_7 929562.Emtol_1398 2.957e-59 214.0 28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,47QT8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5783229_9 643867.Ftrac_1111 2.29e-32 127.0 COG2350@1|root,COG2350@2|Bacteria,4NVYH@976|Bacteroidetes,47SH9@768503|Cytophagia 976|Bacteroidetes S PFAM YCII-related domain - - - ko:K09780 - - - - ko00000 - - - YCII CMS3_k127_5783229_8 1168034.FH5T_17715 1.446e-58 208.0 28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5783229_5 1121904.ARBP01000001_gene5509 9.608e-97 321.0 COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47YFC@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_5783229_1 504472.Slin_6620 8.195e-148 482.0 COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,47MJK@768503|Cytophagia 976|Bacteroidetes M glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_5783229_3 880073.Calab_2100 5.586e-134 446.0 COG2957@1|root,COG2957@2|Bacteria 2|Bacteria E agmatine deiminase activity - - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph CMS3_k127_5783229_6 1121904.ARBP01000004_gene1008 2.923e-81 278.0 COG1646@1|root,COG1646@2|Bacteria,4NER8@976|Bacteroidetes,47MXM@768503|Cytophagia 976|Bacteroidetes I Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) pcrB - - ko:K07094 - - - - ko00000,ko01000 - - - PcrB CMS3_k127_5789612_1 1408433.JHXV01000010_gene529 0.0002005 53.0 COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,4NIDX@976|Bacteroidetes,1I0AY@117743|Flavobacteriia,2PBAP@246874|Cryomorphaceae 976|Bacteroidetes U Concanavalin A-like lectin/glucanases superfamily - - - - - - - - - - - - Laminin_G_3 CMS3_k127_5789612_0 1313304.CALK_0823 2.079e-103 345.0 COG0162@1|root,COG0162@2|Bacteria 2|Bacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b CMS3_k127_5790770_2 762903.Pedsa_1293 7.868e-62 217.0 COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1ISGU@117747|Sphingobacteriia 976|Bacteroidetes K Belongs to the GbsR family - - - - - - - - - - - - HTH_5,MarR_2,TrmB CMS3_k127_5790770_1 743722.Sph21_3955 5.54e-229 733.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,1IPW0@117747|Sphingobacteriia 976|Bacteroidetes J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind CMS3_k127_5790770_3 443143.GM18_1260 4.781e-47 186.0 COG4251@1|root,COG4936@1|root,COG5000@1|root,COG4251@2|Bacteria,COG4936@2|Bacteria,COG5000@2|Bacteria,1NSQ1@1224|Proteobacteria,42QPS@68525|delta/epsilon subdivisions,2WMWT@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - CHASE3,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,dCache_1 CMS3_k127_5790770_0 743722.Sph21_2236 0.0 1182.0 COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia 976|Bacteroidetes C aconitate hydratase acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C CMS3_k127_5790770_4 929562.Emtol_1953 1.218e-09 61.0 COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,47K9S@768503|Cytophagia 976|Bacteroidetes EQ Peptidase family S58 - - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 CMS3_k127_5793753_3 926549.KI421517_gene345 1.113e-53 198.0 COG0755@1|root,COG0755@2|Bacteria,4NFUS@976|Bacteroidetes,47MYQ@768503|Cytophagia 976|Bacteroidetes O PFAM Cytochrome c assembly protein ccmC - - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm CMS3_k127_5793753_4 762903.Pedsa_1827 2.392e-52 192.0 COG2386@1|root,COG2386@2|Bacteria,4NFQV@976|Bacteroidetes,1IP2M@117747|Sphingobacteriia 976|Bacteroidetes O PFAM Cytochrome c-type biogenesis protein CcmB ccmB - - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB CMS3_k127_5793753_1 1237149.C900_05420 1.627e-257 802.0 COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia 976|Bacteroidetes C TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 pruA - 1.2.1.88,1.5.5.2 ko:K00294,ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh CMS3_k127_5793753_5 1229276.DI53_2577 2.283e-40 163.0 COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IQZY@117747|Sphingobacteriia 976|Bacteroidetes Q ABC-type transport system involved in resistance to organic solvents periplasmic component - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD CMS3_k127_5793753_0 1313301.AUGC01000003_gene2172 1.355e-272 854.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes 976|Bacteroidetes C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type bfmBA - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C CMS3_k127_5793753_2 1270196.JCKI01000008_gene1400 6.195e-62 218.0 COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,1ISBJ@117747|Sphingobacteriia 976|Bacteroidetes L NUDIX domain nudF - - - - - - - - - - - NUDIX CMS3_k127_5795279_0 643867.Ftrac_3236 3.214e-130 428.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia 976|Bacteroidetes L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 CMS3_k127_5795279_4 313606.M23134_07545 2.222e-49 184.0 COG0406@1|root,COG0406@2|Bacteria,4NNN0@976|Bacteroidetes,47Q0B@768503|Cytophagia 976|Bacteroidetes G Phosphoglycerate mutase family - - 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 CMS3_k127_5795279_1 313606.M23134_05392 1.452e-102 342.0 COG0388@1|root,COG0388@2|Bacteria,4NGH7@976|Bacteroidetes,47NQU@768503|Cytophagia 976|Bacteroidetes S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase CMS3_k127_5795279_3 1380384.JADN01000007_gene1692 4.582e-57 204.0 COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,1I28A@117743|Flavobacteriia 976|Bacteroidetes S DinB superfamily yfiT - - - - - - - - - - - DinB_2 CMS3_k127_5795279_2 1282360.ABAC460_06145 1.682e-61 214.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,2KF1K@204458|Caulobacterales 204458|Caulobacterales L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH CMS3_k127_5800562_0 1121904.ARBP01000009_gene4221 5.006e-208 665.0 COG1874@1|root,COG1874@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Cellulase,Glyco_hydro_35,Glyco_hydro_42,Glyco_hydro_42M,Sulfotransfer_2 CMS3_k127_5800562_1 1408473.JHXO01000012_gene342 1.214e-136 443.0 COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,2FNA4@200643|Bacteroidia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 18 family - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - Glyco_hydro_18 CMS3_k127_5802711_3 1408473.JHXO01000011_gene3188 7.103e-18 85.0 COG1210@1|root,COG1210@2|Bacteria,4NF1P@976|Bacteroidetes,2FYIC@200643|Bacteroidia 976|Bacteroidetes GM Nucleotidyl transferase - - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_N,NTP_transferase CMS3_k127_5802711_0 326427.Cagg_1111 2.017e-86 295.0 COG2423@1|root,COG2423@2|Bacteria,2G6BQ@200795|Chloroflexi,375XV@32061|Chloroflexia 32061|Chloroflexia E PFAM ornithine cyclodeaminase mu-crystallin - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall CMS3_k127_5802711_1 313606.M23134_04812 4.498e-59 219.0 28KF4@1|root,2ZA1C@2|Bacteria,4NNRR@976|Bacteroidetes,47UXU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - BetR CMS3_k127_5802711_2 1358423.N180_12200 1.839e-20 92.0 COG0694@1|root,COG0694@2|Bacteria,4NSHJ@976|Bacteroidetes,1IU7U@117747|Sphingobacteriia 976|Bacteroidetes O NifU-like domain nfuA - - - - - - - - - - - NifU CMS3_k127_5807063_2 1121377.KB906423_gene3740 2.935e-32 128.0 COG1131@1|root,COG1131@2|Bacteria,1WM2S@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran CMS3_k127_5807063_0 755732.Fluta_2455 5.698e-101 337.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1HXMC@117743|Flavobacteriia,2PAFP@246874|Cryomorphaceae 976|Bacteroidetes C Transketolase, pyrimidine binding domain bfmBAB - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C CMS3_k127_5807063_5 93220.LV28_24150 1.579e-15 87.0 COG0457@1|root,COG0457@2|Bacteria 93220.LV28_24150|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - CMS3_k127_5807063_6 1086011.HJ01_02049 9.601e-05 53.0 29K0G@1|root,306XS@2|Bacteria,4NNVI@976|Bacteroidetes,1I21S@117743|Flavobacteriia,2NVY8@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5807063_1 1122176.KB903531_gene3012 4.296e-67 232.0 COG1595@1|root,COG1595@2|Bacteria,4NQCH@976|Bacteroidetes,1ISH7@117747|Sphingobacteriia 976|Bacteroidetes K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog - - - ko:K03088 - - - - ko00000,ko03021 - - - OMP_b-brl_2,Sigma70_r2,Sigma70_r4_2 CMS3_k127_5807063_4 926562.Oweho_1584 7.725e-17 91.0 2E7J5@1|root,3321E@2|Bacteria,4NWSR@976|Bacteroidetes,1I9ID@117743|Flavobacteriia,2PB0F@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - DUF4340 CMS3_k127_5807063_3 760192.Halhy_3015 7.959e-22 101.0 COG3637@1|root,COG3637@2|Bacteria,4NUEN@976|Bacteroidetes,1J0BJ@117747|Sphingobacteriia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl CMS3_k127_5809021_2 926556.Echvi_0789 4.108e-121 400.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,47Y5U@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5809021_0 1122176.KB903536_gene1870 1.459e-196 631.0 COG3118@1|root,COG3118@2|Bacteria,4PMAJ@976|Bacteroidetes 976|Bacteroidetes O Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotrans CMS3_k127_5809021_1 1408433.JHXV01000002_gene442 9.233e-159 521.0 COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia 976|Bacteroidetes G Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotrans CMS3_k127_5809021_3 313590.MED134_12371 1.055e-14 81.0 2AM3F@1|root,31BXJ@2|Bacteria,4NPAN@976|Bacteroidetes,1I2M5@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5811747_0 1121904.ARBP01000003_gene6128 3.481e-155 497.0 COG1629@1|root,COG4771@2|Bacteria,4NF05@976|Bacteroidetes,47K7I@768503|Cytophagia 976|Bacteroidetes P Outer membrane receptor for ferrienterochelin and colicins - - - ko:K16089 - - - - ko00000,ko02000 1.B.14.1,1.B.14.10 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5811747_4 1121904.ARBP01000003_gene6129 2.448e-34 137.0 COG4232@1|root,COG4232@2|Bacteria,4PM8A@976|Bacteroidetes,47RUB@768503|Cytophagia 976|Bacteroidetes CO Protein of unknown function, DUF255 - - - - - - - - - - - - Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7 CMS3_k127_5811747_3 880071.Fleli_1257 2.626e-37 142.0 COG2343@1|root,COG2343@2|Bacteria,4NSIC@976|Bacteroidetes,47RG1@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF427) - - - - - - - - - - - - NTP_transf_9 CMS3_k127_5811747_5 1313421.JHBV01000039_gene2759 4.262e-15 90.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NFMW@976|Bacteroidetes,1IW54@117747|Sphingobacteriia 976|Bacteroidetes O SPTR Peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - CARDB,MAM,PKD,Peptidase_S8 CMS3_k127_5811747_1 1313421.JHBV01000043_gene3107 8.593e-51 205.0 COG1520@1|root,COG2931@1|root,COG3291@1|root,COG4935@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,4PI1E@976|Bacteroidetes,1IYUU@117747|Sphingobacteriia 976|Bacteroidetes Q Immunoglobulin - - - - - - - - - - - - - CMS3_k127_5811747_2 926562.Oweho_2546 5.225e-41 160.0 COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,1HWQF@117743|Flavobacteriia,2PADY@246874|Cryomorphaceae 976|Bacteroidetes S Membrane protein involved in the export of O-antigen and teichoic acid cap - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C CMS3_k127_5818422_1 172045.KS04_08095 3.782e-66 232.0 COG0637@1|root,COG0637@2|Bacteria,4NIYB@976|Bacteroidetes,1IMMU@117743|Flavobacteriia,34QDZ@308865|Elizabethkingia 976|Bacteroidetes S HAD-hyrolase-like phnX - 3.11.1.1 ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R00747 RC00368 ko00000,ko00001,ko01000 - - - HAD_2 CMS3_k127_5818422_0 1121895.Q765_10410 4.911e-149 481.0 COG0665@1|root,COG0665@2|Bacteria,4NFPQ@976|Bacteroidetes,1HX5D@117743|Flavobacteriia,2NVHC@237|Flavobacterium 976|Bacteroidetes E FAD dependent oxidoreductase - - - - - - - - - - - - DAO CMS3_k127_5818422_2 1121288.AULL01000015_gene84 1.583e-26 119.0 COG1404@1|root,COG3591@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,4NU3G@976|Bacteroidetes,1I62K@117743|Flavobacteriia 976|Bacteroidetes EO Trypsin-like peptidase domain - - - - - - - - - - - - Peptidase_S8,Trypsin_2 CMS3_k127_5828297_4 1121931.AUHG01000019_gene3037 3.46e-78 264.0 COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia 976|Bacteroidetes E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 CMS3_k127_5828297_2 1249975.JQLP01000001_gene2849 6.125e-188 608.0 COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia,2P5IB@244698|Gillisia 976|Bacteroidetes E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 CMS3_k127_5828297_5 1150600.ADIARSV_3728 7.54e-21 101.0 2B0RK@1|root,31T3U@2|Bacteria,4NQWT@976|Bacteroidetes,1ISS6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - ACP_PD CMS3_k127_5828297_3 1121904.ARBP01000004_gene843 4.812e-91 312.0 COG2067@1|root,COG2067@2|Bacteria,4NE43@976|Bacteroidetes,47KIV@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - - CMS3_k127_5828297_1 1237149.C900_05632 1.194e-199 681.0 COG1572@1|root,COG1572@2|Bacteria,4NFAX@976|Bacteroidetes,47K9M@768503|Cytophagia 976|Bacteroidetes S Peptidase family C25 - - - - - - - - - - - - CARDB,FlgD_ig,ILEI,Peptidase_C25 CMS3_k127_5828297_0 1286632.P278_31850 4.394e-212 670.0 COG0423@1|root,COG0423@2|Bacteria,4NE1C@976|Bacteroidetes,1HX2K@117743|Flavobacteriia 976|Bacteroidetes J Belongs to the class-II aminoacyl-tRNA synthetase family glyQS - 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b CMS3_k127_5828297_6 926549.KI421517_gene389 2.237e-14 76.0 COG3637@1|root,COG3637@2|Bacteria,4NQ11@976|Bacteroidetes,47M42@768503|Cytophagia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - OMP_b-brl CMS3_k127_5831404_4 755732.Fluta_2092 1.695e-51 204.0 COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1I0R3@117743|Flavobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,HYR,PKD,SprB CMS3_k127_5831404_7 929556.Solca_3750 4.435e-31 125.0 COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,1ITA5@117747|Sphingobacteriia 976|Bacteroidetes J Translation initiation factor - - - ko:K03113 ko03013,map03013 - - - ko00000,ko00001,ko03012 - - - SUI1 CMS3_k127_5831404_3 926549.KI421517_gene3844 1.871e-106 390.0 COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,47KQP@768503|Cytophagia 976|Bacteroidetes S PFAM Family of - - - - - - - - - - - - TamB CMS3_k127_5831404_2 1150600.ADIARSV_3939 3.478e-137 443.0 COG0533@1|root,COG0533@2|Bacteria,4NE8E@976|Bacteroidetes,1INZZ@117747|Sphingobacteriia 976|Bacteroidetes O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CMS3_k127_5831404_1 153721.MYP_781 6.223e-173 573.0 COG1629@1|root,COG1629@2|Bacteria,4NFFN@976|Bacteroidetes,47XZ4@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug CMS3_k127_5831404_6 714943.Mucpa_5785 8.691e-44 170.0 COG0115@1|root,COG0115@2|Bacteria,4NG0G@976|Bacteroidetes,1IPBG@117747|Sphingobacteriia 976|Bacteroidetes EH Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase ilvE - 2.6.1.42,4.1.3.38 ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R05553,R10991 RC00006,RC00036,RC01843,RC02148 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 CMS3_k127_5831404_9 1144313.PMI10_02852 3.378e-10 70.0 COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes,1HYE4@117743|Flavobacteriia,2NT1B@237|Flavobacterium 976|Bacteroidetes T Belongs to the universal stress protein A family uspA - - - - - - - - - - - Usp CMS3_k127_5831404_5 1408473.JHXO01000008_gene2875 2.715e-48 181.0 COG0705@1|root,COG0705@2|Bacteria,4NGT3@976|Bacteroidetes,2FMIT@200643|Bacteroidia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Rhomboid CMS3_k127_5831404_0 1121373.KB903622_gene2826 8.852e-224 708.0 COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,47KUE@768503|Cytophagia 976|Bacteroidetes P Belongs to the ABC transporter superfamily gsiA - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY CMS3_k127_5831404_8 1313421.JHBV01000015_gene5755 4.775e-28 121.0 COG0265@1|root,COG3209@1|root,COG3291@1|root,COG5337@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria 2|Bacteria M Spore coat protein CotH - - 3.4.21.107,3.4.21.50 ko:K01337,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - Collagen,CotH,Fn3_assoc,LTD CMS3_k127_5842712_0 761193.Runsl_4225 4.929e-305 942.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia 976|Bacteroidetes EU Dipeptidyl peptidase IV (DPP IV) N-terminal region - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 CMS3_k127_5842712_1 382464.ABSI01000010_gene3519 2.542e-155 498.0 COG1621@1|root,COG1621@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 32 family - - - - - - - - - - - - Glyco_hydro_32N,Glyco_hydro_43 CMS3_k127_5842712_2 946077.W5A_09234 5.025e-22 99.0 COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,1HZYU@117743|Flavobacteriia 976|Bacteroidetes G alpha-L-fucosidase fucA - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc CMS3_k127_5847373_1 926556.Echvi_0372 3.108e-100 337.0 COG1559@1|root,COG1559@2|Bacteria,4NG17@976|Bacteroidetes,47J93@768503|Cytophagia 976|Bacteroidetes S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG CMS3_k127_5847373_2 471854.Dfer_1953 4.56e-71 248.0 COG0494@1|root,COG0494@2|Bacteria,4NM2N@976|Bacteroidetes,47NYX@768503|Cytophagia 976|Bacteroidetes L PFAM NUDIX hydrolase - - - - - - - - - - - - NUDIX CMS3_k127_5847373_0 909943.HIMB100_00019800 3.458e-158 517.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,4BP7U@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind CMS3_k127_5848094_0 1122176.KB903538_gene1448 4.185e-141 453.0 COG1032@1|root,COG1032@2|Bacteria,4NH8Y@976|Bacteroidetes,1IRE5@117747|Sphingobacteriia 976|Bacteroidetes C B12 binding domain - - - - - - - - - - - - B12-binding,Radical_SAM CMS3_k127_5848094_4 479434.Sthe_3410 2.958e-26 119.0 COG0500@1|root,COG2890@1|root,COG2226@2|Bacteria,COG2890@2|Bacteria,2G9F9@200795|Chloroflexi 200795|Chloroflexi Q Methyltransferase domain - - - - - - - - - - - - - CMS3_k127_5848094_3 1122176.KB903538_gene1451 5.957e-39 160.0 2FDRJ@1|root,345SI@2|Bacteria,4P5E6@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - Polysacc_synt_C CMS3_k127_5848094_1 391587.KAOT1_19382 3.208e-67 243.0 COG0438@1|root,COG0438@2|Bacteria,4NPXB@976|Bacteroidetes,1I7TH@117743|Flavobacteriia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 CMS3_k127_5848094_2 1121904.ARBP01000006_gene3816 7.789e-57 203.0 COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NHVG@976|Bacteroidetes,47M7T@768503|Cytophagia 976|Bacteroidetes CG TIGRFAM membrane-bound dehydrogenase domain protein - - - - - - - - - - - - Cytochrom_C,GSDH,HEAT_2 CMS3_k127_5850562_0 1239415.CM001837_gene2961 0.0 1055.0 COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,1IGB4@117743|Flavobacteriia,37FPQ@326319|Dokdonia 976|Bacteroidetes S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS3_k127_5850562_1 1121904.ARBP01000003_gene6331 6.145e-77 270.0 COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47N72@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_5850562_2 5911.EAR82403 3.246e-07 61.0 COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora 5878|Ciliophora GOT TPR Domain containing protein - - - ko:K12600 ko03018,map03018 M00392 - - ko00000,ko00001,ko00002,ko03019 - - - TPR_1,TPR_11,TPR_2,TPR_8 CMS3_k127_58510_0 401053.AciPR4_0237 8.872e-160 519.0 COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia 204432|Acidobacteriia Q Amidohydrolase family - - 3.5.1.81 ko:K06015 - - R02192 RC00064,RC00328 ko00000,ko01000 - - - Amidohydro_3 CMS3_k127_5854209_0 468059.AUHA01000006_gene2939 2.161e-307 962.0 COG0466@1|root,COG0466@2|Bacteria,4NE1G@976|Bacteroidetes,1IQDQ@117747|Sphingobacteriia 976|Bacteroidetes O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C CMS3_k127_5854209_1 643867.Ftrac_3298 5.43e-26 113.0 2DEYG@1|root,2ZPSM@2|Bacteria,4NNJW@976|Bacteroidetes,47VMD@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5854209_2 1173023.KE650771_gene1935 8.347e-13 74.0 COG4244@1|root,COG4244@2|Bacteria,1GDT1@1117|Cyanobacteria 1117|Cyanobacteria S Predicted membrane protein (DUF2231) - - - - - - - - - - - - DUF2231 CMS3_k127_5854209_3 1185876.BN8_02270 1.331e-10 68.0 28HQQ@1|root,2Z7YB@2|Bacteria,4NJCY@976|Bacteroidetes,47QT8@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5858864_3 485918.Cpin_6374 1.055e-60 216.0 COG1309@1|root,COG1309@2|Bacteria,4NP6I@976|Bacteroidetes,1IY2Z@117747|Sphingobacteriia 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_13,TetR_N CMS3_k127_5858864_1 362418.IW19_22625 3.074e-95 321.0 COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,1I5ZB@117743|Flavobacteriia,2P022@237|Flavobacterium 976|Bacteroidetes S Alpha/beta hydrolase family - - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS3_k127_5858864_2 153721.MYP_1423 1.852e-61 215.0 COG3324@1|root,COG3324@2|Bacteria,4PKMI@976|Bacteroidetes,47XWK@768503|Cytophagia 976|Bacteroidetes E translation initiation factor activity - - - - - - - - - - - - Glyoxalase CMS3_k127_5858864_0 1107311.Q767_15120 1.677e-98 325.0 COG0262@1|root,COG0262@2|Bacteria,4NIN1@976|Bacteroidetes,1I1SM@117743|Flavobacteriia,2P0ET@237|Flavobacterium 976|Bacteroidetes H RibD C-terminal domain - - - - - - - - - - - - RibD_C CMS3_k127_5860430_1 269798.CHU_2012 5.786e-11 72.0 COG0457@1|root,COG0457@2|Bacteria,4NIEU@976|Bacteroidetes,47XPU@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_8 CMS3_k127_5860430_0 880070.Cycma_1982 2.128e-179 576.0 COG4206@1|root,COG4206@2|Bacteria,4NZWU@976|Bacteroidetes,47N6U@768503|Cytophagia 976|Bacteroidetes H TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_5860648_0 641526.ADIWIN_3152 6.85e-140 456.0 COG1696@1|root,COG1696@2|Bacteria,4NFK5@976|Bacteroidetes,1HWM1@117743|Flavobacteriia 976|Bacteroidetes M Membrane protein involved in D-alanine export - - - - - - - - - - - - MBOAT CMS3_k127_5860648_1 153721.MYP_561 9.176e-121 405.0 COG3307@1|root,COG3307@2|Bacteria,4NGGY@976|Bacteroidetes,47JK2@768503|Cytophagia 976|Bacteroidetes M O-Antigen ligase - - - - - - - - - - - - Wzy_C CMS3_k127_5862646_5 1121904.ARBP01000013_gene400 6.42e-103 339.0 COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,47SW9@768503|Cytophagia 976|Bacteroidetes M Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like CMS3_k127_5862646_0 1122176.KB903587_gene4540 9.114e-171 545.0 COG4591@1|root,COG4591@2|Bacteria,4NJRI@976|Bacteroidetes 976|Bacteroidetes M COG4591 ABC-type transport system, involved in lipoprotein release, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_5862646_2 1122176.KB903587_gene4541 5.702e-135 440.0 COG4591@1|root,COG4591@2|Bacteria,4NKUN@976|Bacteroidetes,1J1AB@117747|Sphingobacteriia 976|Bacteroidetes M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX CMS3_k127_5862646_4 1123008.KB905694_gene1576 4.096e-103 340.0 COG1136@1|root,COG1136@2|Bacteria,4NGY1@976|Bacteroidetes,2FRNC@200643|Bacteroidia,23086@171551|Porphyromonadaceae 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_5862646_3 1122176.KB903587_gene4543 1.659e-134 439.0 28HAJ@1|root,2Z7MX@2|Bacteria,4NKQQ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5862646_6 1122176.KB903587_gene4544 3.047e-49 182.0 COG1309@1|root,COG1309@2|Bacteria,4NU6H@976|Bacteroidetes 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CMS3_k127_5862646_1 555500.I215_10305 6.868e-161 522.0 COG0322@1|root,COG0322@2|Bacteria,4NE61@976|Bacteroidetes,1HWQN@117743|Flavobacteriia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N CMS3_k127_5865287_3 1239962.C943_00259 1.07e-59 208.0 COG2334@1|root,COG2334@2|Bacteria,4NEUT@976|Bacteroidetes,47M0W@768503|Cytophagia 976|Bacteroidetes S glucosidase - - - - - - - - - - - - Glyco_hydro_63 CMS3_k127_5865287_2 620914.JH621260_gene882 2.38e-164 530.0 COG1834@1|root,COG1834@2|Bacteria,4P05A@976|Bacteroidetes,1IK0T@117743|Flavobacteriia,2YM63@290174|Aquimarina 976|Bacteroidetes E Pfam:SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_5865287_0 620914.JH621260_gene881 0.0 1167.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2YIU3@290174|Aquimarina 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5865287_1 1122176.KB903554_gene3913 2.205e-193 626.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_5870746_3 1237149.C900_02516 1.291e-14 75.0 COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5870746_1 643867.Ftrac_2415 5.472e-146 478.0 COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor fecA - - ko:K16091 - - - - ko00000,ko02000 1.B.14.1.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_5870746_0 1122179.KB890439_gene1635 4.119e-158 510.0 COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1IQ5B@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_5870746_2 700598.Niako_1274 2.519e-72 257.0 COG1752@1|root,COG1752@2|Bacteria,4NMUK@976|Bacteroidetes,1ISPD@117747|Sphingobacteriia 976|Bacteroidetes S Phospholipase, patatin family - - - ko:K07001 - - - - ko00000 - - - Patatin CMS3_k127_5874316_3 1233950.IW22_17905 0.000543 50.0 COG4783@1|root,COG4783@2|Bacteria,4NJ2X@976|Bacteroidetes,1I05N@117743|Flavobacteriia,3ZT3R@59732|Chryseobacterium 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 CMS3_k127_5874316_0 1250232.JQNJ01000001_gene3314 0.0 1506.0 2DB7A@1|root,2Z7KK@2|Bacteria,4NGC2@976|Bacteroidetes,1HYSC@117743|Flavobacteriia 976|Bacteroidetes S Glycosyl hydrolase family 115 - - - - - - - - - - - - Glyco_hydro_115,Glyco_hydro_67N CMS3_k127_5874316_1 314230.DSM3645_02338 1.346e-13 75.0 COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A and related enzymes - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_5874316_2 497964.CfE428DRAFT_3913 3.226e-09 62.0 COG3119@1|root,COG3119@2|Bacteria,46TFH@74201|Verrucomicrobia 74201|Verrucomicrobia P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_5875335_1 877414.ATWA01000009_gene2465 2.88e-05 53.0 COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia 186801|Clostridia L virion core protein (lumpy skin disease virus) - - - - - - - - - - - - Band_7_1,SHOCT CMS3_k127_5875335_0 1120950.KB892762_gene5508 1.436e-24 106.0 COG4274@1|root,COG4274@2|Bacteria,2HWQ8@201174|Actinobacteria,4DW30@85009|Propionibacteriales 201174|Actinobacteria S GYD domain - - - - - - - - - - - - GYD CMS3_k127_5892473_0 1123277.KB893195_gene5653 3.033e-198 625.0 COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,47KAP@768503|Cytophagia 976|Bacteroidetes G Glucuronate isomerase uxaC - 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - - UxaC CMS3_k127_5892473_1 1124780.ANNU01000008_gene2696 2.695e-109 359.0 COG1638@1|root,COG1638@2|Bacteria,4NGV4@976|Bacteroidetes,47MM2@768503|Cytophagia 976|Bacteroidetes G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS3_k127_5893426_1 1123057.P872_07695 1.215e-14 78.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5893426_0 1121904.ARBP01000001_gene5708 1.658e-69 251.0 COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia 976|Bacteroidetes M PDZ DHR GLGF domain protein - - - - - - - - - - - - Asp_protease_2,PDZ,PDZ_2 CMS3_k127_5897274_1 497964.CfE428DRAFT_2188 8.221e-49 190.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_5897274_3 1111479.AXAR01000007_gene888 3.544e-14 81.0 COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,4HCG7@91061|Bacilli,27A3C@186823|Alicyclobacillaceae 91061|Bacilli M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_5897274_2 1227739.Hsw_1662 6.794e-21 100.0 COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 CMS3_k127_5897274_4 468059.AUHA01000004_gene2135 1.619e-10 71.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_3,Glycos_transf_1,Glycos_transf_2 CMS3_k127_5897274_0 926549.KI421517_gene1701 1.489e-122 414.0 COG1132@1|root,COG1132@2|Bacteria,4NIFZ@976|Bacteroidetes,47TDF@768503|Cytophagia 976|Bacteroidetes V ATPases associated with a variety of cellular activities - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran CMS3_k127_5897426_5 1249997.JHZW01000002_gene1810 7.886e-11 72.0 COG1073@1|root,COG1073@2|Bacteria,4PP77@976|Bacteroidetes,1IKU7@117743|Flavobacteriia 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 CMS3_k127_5897426_1 1123277.KB893179_gene3115 7.806e-85 287.0 COG1999@1|root,COG1999@2|Bacteria,4NFH2@976|Bacteroidetes,47PXC@768503|Cytophagia 976|Bacteroidetes S PFAM SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC CMS3_k127_5897426_3 1121904.ARBP01000006_gene3749 3.949e-34 139.0 COG2849@1|root,COG2849@2|Bacteria,4NSKP@976|Bacteroidetes,47R1D@768503|Cytophagia 976|Bacteroidetes S PFAM MORN repeat variant - - - - - - - - - - - - MORN_2 CMS3_k127_5897426_0 714943.Mucpa_4236 2.844e-104 344.0 COG1881@1|root,COG1881@2|Bacteria,4NGHZ@976|Bacteroidetes,1IY0F@117747|Sphingobacteriia 976|Bacteroidetes S YHYH protein - - - - - - - - - - - - YHYH CMS3_k127_5897426_4 1150600.ADIARSV_2314 4.926e-25 110.0 COG3678@1|root,COG3678@2|Bacteria,4PA3G@976|Bacteroidetes,1IUMB@117747|Sphingobacteriia 976|Bacteroidetes NPTU ATP-independent chaperone mediated protein folding - - - - - - - - - - - - - CMS3_k127_5897426_2 1123278.KB893387_gene4373 1.003e-48 181.0 COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,47QT5@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5900739_1 760192.Halhy_2425 6.99e-102 341.0 COG1703@1|root,COG1703@2|Bacteria,4NE7Y@976|Bacteroidetes,1IQ92@117747|Sphingobacteriia 976|Bacteroidetes E LAO AO transport system ATPase argK - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK CMS3_k127_5900739_3 926562.Oweho_1502 3.196e-30 127.0 28NWP@1|root,2ZBUH@2|Bacteria,4NNPT@976|Bacteroidetes,1I253@117743|Flavobacteriia,2PB3I@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5900739_0 925409.KI911562_gene1508 3.548e-179 575.0 COG0593@1|root,COG0593@2|Bacteria,4NE6Q@976|Bacteroidetes,1INXF@117747|Sphingobacteriia 976|Bacteroidetes L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N CMS3_k127_5900739_2 1122179.KB890427_gene3834 3.862e-85 292.0 COG0803@1|root,COG0803@2|Bacteria,4NGMC@976|Bacteroidetes,1IYDH@117747|Sphingobacteriia 976|Bacteroidetes P Zinc-uptake complex component A periplasmic mntA - - ko:K09815,ko:K11707 ko02010,map02010 M00242,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZnuA CMS3_k127_5919949_2 1305737.JAFX01000001_gene336 8.17e-08 54.0 COG1669@1|root,COG1669@2|Bacteria,4NV8X@976|Bacteroidetes 976|Bacteroidetes S PFAM Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 CMS3_k127_5919949_3 870187.Thini_2446 2.14e-06 54.0 COG2361@1|root,COG2361@2|Bacteria,1N6ZA@1224|Proteobacteria,1SBHC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 CMS3_k127_5919949_1 272134.KB731324_gene2088 4.695e-12 67.0 COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HAMP,HATPase_c,HisKA,PAS,PAS_8,PG_binding_1,Response_reg,dCache_1 CMS3_k127_5919949_0 1499967.BAYZ01000095_gene4203 2.667e-93 345.0 COG0642@1|root,COG3292@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,2NQMI@2323|unclassified Bacteria 2|Bacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - GGDEF,HATPase_c,HisKA,Hpt,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_5933656_1 1121930.AQXG01000003_gene2476 2.798e-08 64.0 COG1983@1|root,COG1983@2|Bacteria 2|Bacteria KT positive regulation of macromolecule biosynthetic process pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC CMS3_k127_5933656_0 471854.Dfer_2120 2.885e-12 79.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - PA,PPC,Peptidase_M36 CMS3_k127_5935259_1 518766.Rmar_2339 2.289e-221 691.0 COG2873@1|root,COG2873@2|Bacteria,4NE27@976|Bacteroidetes,1FJ01@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein metZ - 2.5.1.49 ko:K01740,ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 - R01287,R01288,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_5935259_4 1009370.ALO_07418 4.924e-57 204.0 COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4H4R5@909932|Negativicutes 909932|Negativicutes S domain protein - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 CMS3_k127_5935259_5 1237149.C900_03399 9.754e-18 89.0 28WK7@1|root,2ZIK7@2|Bacteria,4P8ND@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_5935259_3 864702.OsccyDRAFT_4062 4.188e-65 228.0 COG1611@1|root,COG1611@2|Bacteria,1GC1H@1117|Cyanobacteria,1HFBA@1150|Oscillatoriales 1117|Cyanobacteria S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox CMS3_k127_5935259_0 1122176.KB903533_gene2443 1.506e-243 758.0 COG0673@1|root,COG0673@2|Bacteria,4NIF1@976|Bacteroidetes,1IVYW@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_5935259_2 313606.M23134_01402 4.781e-115 377.0 COG0596@1|root,COG0596@2|Bacteria,4NFBJ@976|Bacteroidetes,47P83@768503|Cytophagia 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 CMS3_k127_5948621_1 1077972.ARGLB_047_00920 2.265e-76 261.0 COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,1WCG2@1268|Micrococcaceae 201174|Actinobacteria P AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran CMS3_k127_5948621_2 1037409.BJ6T_61790 4.78e-26 112.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K01993,ko:K02005 - - - - ko00000 - - - - CMS3_k127_5948621_0 1057002.KB905370_gene3674 8.027e-245 786.0 COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,4BB6Z@82115|Rhizobiaceae 28211|Alphaproteobacteria P cation efflux system protein (Heavy metal efflux pump) - - - - - - - - - - - - ACR_tran CMS3_k127_5948866_0 1121904.ARBP01000006_gene3683 5.042e-224 709.0 COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,47TDS@768503|Cytophagia 976|Bacteroidetes E Phosphotransferase enzyme family - - - - - - - - - - - - APH,Aminotran_3,Peptidase_M23 CMS3_k127_5954873_4 1250232.JQNJ01000001_gene1673 6.378e-09 60.0 COG2849@1|root,COG2849@2|Bacteria,4NJB4@976|Bacteroidetes,1I0QY@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF3352) - - - - - - - - - - - - DUF3352,MORN_2 CMS3_k127_5954873_0 1121373.KB903637_gene964 2.874e-122 396.0 COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47XX0@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_5954873_1 1121373.KB903621_gene1880 1.439e-81 286.0 COG2067@1|root,COG2067@2|Bacteria,4NFFF@976|Bacteroidetes,47NDV@768503|Cytophagia 976|Bacteroidetes I Outer membrane protein transport protein (OMPP1/FadL/TodX) fadL - - ko:K06076 - - - - ko00000,ko02000 1.B.9 - - Toluene_X CMS3_k127_5954873_2 1358423.N180_17425 1.566e-51 199.0 COG2755@1|root,COG2755@2|Bacteria,4NGTK@976|Bacteroidetes,1INR2@117747|Sphingobacteriia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL CMS3_k127_5954873_3 1122176.KB903531_gene3025 1.071e-44 169.0 COG0237@1|root,COG0237@2|Bacteria,4NQKS@976|Bacteroidetes,1IS97@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE CMS3_k127_5954873_5 886377.Murru_3456 1.419e-07 63.0 COG4856@1|root,COG4856@2|Bacteria,4NHJQ@976|Bacteroidetes,1I0BY@117743|Flavobacteriia 976|Bacteroidetes S YbbR-like protein - - - - - - - - - - - - YbbR CMS3_k127_5964451_2 497964.CfE428DRAFT_0351 1.872e-74 257.0 COG4946@1|root,COG4946@2|Bacteria,46TXN@74201|Verrucomicrobia 74201|Verrucomicrobia M Tricorn protease homolog - - - - - - - - - - - - - CMS3_k127_5964451_6 742767.HMPREF9456_00822 4.416e-08 65.0 2B0AS@1|root,31SMT@2|Bacteria,4NQFB@976|Bacteroidetes,2FRMQ@200643|Bacteroidia,2311N@171551|Porphyromonadaceae 976|Bacteroidetes - - - - - - - - - - - - - - OMP_b-brl CMS3_k127_5964451_1 760192.Halhy_5630 5.299e-106 353.0 COG1975@1|root,COG1975@2|Bacteria,4NG02@976|Bacteroidetes,1IQT3@117747|Sphingobacteriia 976|Bacteroidetes O COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family xdhC - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI CMS3_k127_5964451_4 313606.M23134_06302 1.233e-34 138.0 COG0822@1|root,COG0822@2|Bacteria,4P667@976|Bacteroidetes 976|Bacteroidetes C NifU-like N terminal domain - - - ko:K04488 - - - - ko00000 - - - NifU_N CMS3_k127_5964451_0 754477.Q7C_274 4.303e-154 496.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,45ZNF@72273|Thiotrichales 72273|Thiotrichales E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 CMS3_k127_5964451_3 760192.Halhy_1960 8.542e-48 174.0 COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,1IS2D@117747|Sphingobacteriia 976|Bacteroidetes S PFAM YeeE YedE family (DUF395) - - - ko:K07112 - - - - ko00000 - - - Sulf_transp CMS3_k127_5965067_0 760192.Halhy_2122 6.143e-70 267.0 COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,4NEUZ@976|Bacteroidetes 2|Bacteria KLT PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14,Pkinase,Trypsin_2 CMS3_k127_5965067_1 517418.Ctha_2340 3.393e-08 67.0 COG0443@1|root,COG1262@1|root,COG0443@2|Bacteria,COG1262@2|Bacteria,1FF87@1090|Chlorobi 1090|Chlorobi O Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS3_k127_5965914_0 1453500.AT05_08790 5.864e-159 533.0 COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec CMS3_k127_5968421_0 1121904.ARBP01000026_gene693 1.467e-198 626.0 COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_5968421_2 1185876.BN8_00276 1.637e-125 407.0 COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,47MJI@768503|Cytophagia 976|Bacteroidetes S SIS domain - - - - - - - - - - - - SIS_2 CMS3_k127_5968421_1 1189612.A33Q_2663 1.806e-137 445.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47JEN@768503|Cytophagia 976|Bacteroidetes S PFAM ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 CMS3_k127_5980086_4 1120968.AUBX01000015_gene3725 2.609e-57 203.0 COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,47KPZ@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily sigR_3 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_5980086_0 1121904.ARBP01000001_gene5544 1.549e-180 573.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,47JCM@768503|Cytophagia 976|Bacteroidetes O Domain of unknown function (DUF5118) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 CMS3_k127_5980086_1 867900.Celly_0681 9.272e-167 533.0 COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes,1HWUW@117743|Flavobacteriia,1F8G3@104264|Cellulophaga 976|Bacteroidetes O Domain of unknown function (DUF5118) - - - - - - - - - - - - DUF4953,DUF5117,DUF5118 CMS3_k127_5980086_6 1185876.BN8_02865 9.002e-29 121.0 COG0745@1|root,COG1956@1|root,COG5002@1|root,COG0745@2|Bacteria,COG1956@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47YRP@768503|Cytophagia 976|Bacteroidetes T helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - GAF_2,HATPase_c,HTH_18,HisKA,Response_reg,TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_5980086_2 1408433.JHXV01000027_gene3728 4.553e-162 526.0 COG2208@1|root,COG3292@1|root,COG4191@1|root,COG2208@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NG28@976|Bacteroidetes,1I1IG@117743|Flavobacteriia 976|Bacteroidetes KT regulator - - - - - - - - - - - - GerE,Reg_prop,Y_Y_Y CMS3_k127_5980086_5 1123277.KB893174_gene5905 2.613e-45 171.0 COG1131@1|root,COG1131@2|Bacteria,4NNVS@976|Bacteroidetes,47PU8@768503|Cytophagia 976|Bacteroidetes V PFAM ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_5980086_3 99598.Cal7507_3130 1.408e-94 327.0 COG3385@1|root,COG3385@2|Bacteria,1GBUK@1117|Cyanobacteria,1HK07@1161|Nostocales 1117|Cyanobacteria L SPTR Transposase - - - - - - - - - - - - DDE_Tnp_1,Dimer_Tnp_Tn5 CMS3_k127_6004077_3 1449065.JMLL01000010_gene1038 1.964e-13 74.0 COG3938@1|root,COG3938@2|Bacteria,1N02K@1224|Proteobacteria,2TV8N@28211|Alphaproteobacteria,43HUQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Belongs to the proline racemase family - - 5.1.1.4 ko:K01777 ko00330,ko01100,map00330,map01100 - R01255 RC00479 ko00000,ko00001,ko01000 - - - Pro_racemase CMS3_k127_6004077_1 604354.TSIB_0630 3.551e-28 117.0 COG0253@1|root,arCOG02255@2157|Archaea,2XUKZ@28890|Euryarchaeota 28890|Euryarchaeota E COG3938 Proline racemase prr - 5.1.1.4 ko:K01777 ko00330,ko01100,map00330,map01100 - R01255 RC00479 ko00000,ko00001,ko01000 - - - Pro_racemase CMS3_k127_6004077_0 649638.Trad_0396 1.161e-81 279.0 2C3PP@1|root,2Z954@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_6004077_4 1229276.DI53_3565 1.992e-09 66.0 COG2197@1|root,COG2197@2|Bacteria,4P3F3@976|Bacteroidetes,1IY29@117747|Sphingobacteriia 976|Bacteroidetes K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg CMS3_k127_6004077_2 469381.Dpep_1426 1.499e-23 108.0 COG2197@1|root,COG2197@2|Bacteria,3TB23@508458|Synergistetes 508458|Synergistetes K response regulator receiver - - - - - - - - - - - - GerE,Response_reg CMS3_k127_6006219_0 929556.Solca_3303 1.5e-147 487.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1IQ85@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Penicillin binding protein transpeptidase domain - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS3_k127_6006219_1 867902.Ornrh_0698 2.729e-08 66.0 COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1HXND@117743|Flavobacteriia 976|Bacteroidetes S gliding motility protein sprE - - - - - - - - - - - TPR_16,TPR_6,TPR_8 CMS3_k127_6006439_2 1499967.BAYZ01000013_gene6446 4.007e-90 313.0 COG0686@1|root,COG0686@2|Bacteria,2NNTE@2323|unclassified Bacteria 2|Bacteria E Alanine dehydrogenase/PNT, N-terminal domain sdh - 1.5.1.7,1.5.1.8,1.5.1.9 ko:K00290,ko:K14157 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R00716,R02313 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N CMS3_k127_6006439_5 929703.KE386491_gene658 4.303e-19 92.0 2AMB7@1|root,31C6A@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_6006439_1 639030.JHVA01000001_gene2540 4.199e-117 385.0 COG2120@1|root,COG2120@2|Bacteria 2|Bacteria S N-acetylglucosaminylinositol deacetylase activity - - - - - - - - - - - - PIG-L CMS3_k127_6006439_0 641524.ADICYQ_4788 4.253e-129 426.0 2C31A@1|root,2Z7UP@2|Bacteria,4NECU@976|Bacteroidetes,47KY8@768503|Cytophagia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - - CMS3_k127_6006439_3 313606.M23134_07120 7.555e-44 168.0 COG1846@1|root,COG1846@2|Bacteria,4NQ6H@976|Bacteroidetes,47Q98@768503|Cytophagia 976|Bacteroidetes K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_27 CMS3_k127_6006439_4 1121904.ARBP01000002_gene6950 2.936e-24 108.0 COG3409@1|root,COG3409@2|Bacteria,4NQBJ@976|Bacteroidetes,47VG4@768503|Cytophagia 976|Bacteroidetes M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 CMS3_k127_6007205_0 1118054.CAGW01000007_gene3850 5.783e-52 200.0 COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,4HDWV@91061|Bacilli,275KQ@186822|Paenibacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_6007205_1 1408433.JHXV01000044_gene3186 1.56e-43 168.0 COG0472@1|root,COG0472@2|Bacteria,4NGKM@976|Bacteroidetes,1HZEV@117743|Flavobacteriia,2PBMM@246874|Cryomorphaceae 976|Bacteroidetes M Glycosyl transferase family 4 - - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - CoA_binding_3,Glycos_transf_4 CMS3_k127_6007346_2 530564.Psta_0855 4.321e-12 70.0 COG1082@1|root,COG1082@2|Bacteria,2J52H@203682|Planctomycetes 203682|Planctomycetes G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_6007346_1 880071.Fleli_2459 2.459e-88 295.0 COG2128@1|root,COG2128@2|Bacteria,4NEJZ@976|Bacteroidetes,47PGC@768503|Cytophagia 976|Bacteroidetes S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD CMS3_k127_6007346_3 1166018.FAES_4245 8.055e-05 49.0 COG2730@1|root,COG2730@2|Bacteria,4NF3J@976|Bacteroidetes,47M4E@768503|Cytophagia 976|Bacteroidetes G Putative collagen-binding domain of a collagenase - - - - - - - - - - - - Collagen_bind_2,DUF4038 CMS3_k127_6007346_0 1121859.KB890755_gene1164 2.39e-207 674.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes 976|Bacteroidetes P TonB-linked outer membrane protein, SusC RagA family - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6013301_2 1237149.C900_05713 2.885e-43 158.0 COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,47JJI@768503|Cytophagia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 egtB - - - - - - - - - - - DinB_2,FGE-sulfatase CMS3_k127_6013301_0 1124780.ANNU01000019_gene1709 8.258e-105 349.0 COG4301@1|root,COG4301@2|Bacteria,4NEFC@976|Bacteroidetes,47KDA@768503|Cytophagia 976|Bacteroidetes S Histidine-specific methyltransferase, SAM-dependent egtD - - - - - - - - - - - Methyltransf_33 CMS3_k127_6013301_3 649349.Lbys_0715 4.556e-18 85.0 COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,47PTG@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family S41 - - - - - - - - - - - - Peptidase_S41,Tricorn_C1 CMS3_k127_6013301_1 760192.Halhy_1878 6.821e-47 182.0 COG3509@1|root,COG3509@2|Bacteria 2|Bacteria Q xylan catabolic process - - - ko:K03932 - - - - ko00000 - CE1 - Esterase,Esterase_phd CMS3_k127_6014377_0 518766.Rmar_0474 2.15e-120 395.0 COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes 976|Bacteroidetes G Converts alpha-aldose to the beta-anomer galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim CMS3_k127_6014377_1 1045858.Bint_2904 1.62e-18 96.0 COG0457@1|root,COG0457@2|Bacteria 1045858.Bint_2904|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - CMS3_k127_6023660_3 880074.BARVI_10205 6.116e-14 76.0 COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,2FNT5@200643|Bacteroidia,22W7I@171551|Porphyromonadaceae 976|Bacteroidetes O Subtilase family aprN - - - - - - - - - - - Peptidase_S8 CMS3_k127_6023660_2 504487.JCM19302_3319 1.256e-23 104.0 COG1359@1|root,COG1359@2|Bacteria,4NSV0@976|Bacteroidetes,1I40Y@117743|Flavobacteriia 976|Bacteroidetes S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM CMS3_k127_6023660_1 714943.Mucpa_5335 3.477e-78 269.0 COG0682@1|root,COG0682@2|Bacteria,4NDWC@976|Bacteroidetes,1ISI0@117747|Sphingobacteriia 976|Bacteroidetes M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - - - - - - - - - - LGT CMS3_k127_6023660_0 714943.Mucpa_5336 2.169e-234 731.0 COG1964@1|root,COG1964@2|Bacteria,4NGNV@976|Bacteroidetes,1IPRT@117747|Sphingobacteriia 976|Bacteroidetes S 4Fe-4S single cluster domain - - - ko:K06937 - - - - ko00000,ko01000 - - - Fer4_14,Radical_SAM CMS3_k127_6023678_1 760192.Halhy_4333 7.295e-35 138.0 COG0514@1|root,COG0514@2|Bacteria,4P3BY@976|Bacteroidetes 976|Bacteroidetes L HRDC domain - - - - - - - - - - - - HRDC CMS3_k127_6023678_0 760192.Halhy_4003 1.045e-65 248.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1IYA5@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - FGE-sulfatase CMS3_k127_6026681_1 1123277.KB893208_gene2823 8.821e-155 493.0 COG0296@1|root,COG2382@1|root,COG0296@2|Bacteria,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,47MEB@768503|Cytophagia 976|Bacteroidetes P Putative esterase - - - ko:K07214 - - - - ko00000 - - - Esterase CMS3_k127_6026681_0 760192.Halhy_0496 2.277e-196 616.0 COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,1IXM3@117747|Sphingobacteriia 976|Bacteroidetes P PFAM Carbohydrate-binding module 48 (Isoamylase N-terminal domain) - - - ko:K07214 - - - - ko00000 - - - CBM_48,Esterase CMS3_k127_6026681_2 760192.Halhy_0494 5.934e-57 200.0 COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,1IXM3@117747|Sphingobacteriia 976|Bacteroidetes P PFAM Carbohydrate-binding module 48 (Isoamylase N-terminal domain) - - - ko:K07214 - - - - ko00000 - - - CBM_48,Esterase CMS3_k127_6027822_2 1168034.FH5T_09475 2.836e-59 212.0 COG2335@1|root,COG2335@2|Bacteria,4NVI8@976|Bacteroidetes 976|Bacteroidetes M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin CMS3_k127_6027822_3 1122179.KB890426_gene3981 4.352e-54 199.0 COG3291@1|root,COG3291@2|Bacteria,4NQ3X@976|Bacteroidetes 976|Bacteroidetes M Pkd domain containing protein - - - - - - - - - - - - Lectin_legB CMS3_k127_6027822_1 1124780.ANNU01000002_gene1611 1.515e-60 226.0 COG0457@1|root,COG0457@2|Bacteria,4P246@976|Bacteroidetes,47PGN@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_6027822_0 1122176.KB903569_gene3490 2.604e-66 243.0 2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1ITQ6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6028209_0 1121930.AQXG01000009_gene278 2.407e-215 686.0 COG0517@1|root,COG0517@2|Bacteria,4NGW0@976|Bacteroidetes,1IV0R@117747|Sphingobacteriia 976|Bacteroidetes S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS,GCS2 CMS3_k127_6028209_1 760192.Halhy_4149 3.036e-101 342.0 COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1IQP5@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_6028209_2 1304284.L21TH_0785 1.154e-20 101.0 COG5522@1|root,COG5522@2|Bacteria,1V4XE@1239|Firmicutes,24Q8V@186801|Clostridia,36KVT@31979|Clostridiaceae 186801|Clostridia S Integral membrane protein (intg_mem_TP0381) - - - - - - - - - - - - Intg_mem_TP0381 CMS3_k127_6028911_3 926549.KI421517_gene2279 3.846e-07 60.0 28HG4@1|root,2Z7S0@2|Bacteria,4NE3G@976|Bacteroidetes,47JTS@768503|Cytophagia 976|Bacteroidetes S TIGRFAM Gliding motility-associated protein GldM gldM - - - - - - - - - - - GldM_C,GldM_N CMS3_k127_6028911_2 1121957.ATVL01000006_gene3103 3.893e-22 100.0 2DN6W@1|root,32UIF@2|Bacteria,4PKBE@976|Bacteroidetes,47VE0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6028911_0 216432.CA2559_10763 2.437e-93 310.0 COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,1HXUY@117743|Flavobacteriia 976|Bacteroidetes G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA CMS3_k127_6028911_1 1122176.KB903554_gene3913 5.727e-27 124.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_6042477_2 760192.Halhy_5814 2.114e-74 274.0 COG0497@1|root,COG1672@1|root,COG0497@2|Bacteria,COG1672@2|Bacteria 2|Bacteria L DNA recombination recN - - ko:K03631,ko:K06921,ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko02000,ko03400 3.A.1.112,8.A.1 - - SMC_N,YkyA CMS3_k127_6042477_1 760192.Halhy_1174 2.912e-91 323.0 COG4995@1|root,COG4995@2|Bacteria,4NZ2B@976|Bacteroidetes,1IZA2@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT CMS3_k127_6042477_0 760192.Halhy_3588 0.0 1064.0 COG0308@1|root,COG0308@2|Bacteria,4NE13@976|Bacteroidetes,1IRI8@117747|Sphingobacteriia 976|Bacteroidetes E COG0308 Aminopeptidase N - - - - - - - - - - - - Peptidase_M1 CMS3_k127_6043997_1 1124780.ANNU01000008_gene2662 4.433e-148 478.0 COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia 976|Bacteroidetes Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6043997_0 1121904.ARBP01000003_gene6209 6.397e-231 727.0 COG0664@1|root,COG0664@2|Bacteria,4NEWA@976|Bacteroidetes,47KHF@768503|Cytophagia 976|Bacteroidetes T - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - - CMS3_k127_6043997_3 946077.W5A_08222 3.593e-46 172.0 COG0457@1|root,COG0457@2|Bacteria,4NQ40@976|Bacteroidetes,1I2EF@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_6043997_2 1453505.JASY01000008_gene783 8.117e-69 246.0 COG3547@1|root,COG3547@2|Bacteria,4NF2F@976|Bacteroidetes,1HXCM@117743|Flavobacteriia,2NVKT@237|Flavobacterium 976|Bacteroidetes L 4.5 Transposon and IS - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 CMS3_k127_6055521_3 1116232.AHBF01000163_gene5875 5.566e-14 85.0 COG5512@1|root,COG5512@2|Bacteria,2HUUR@201174|Actinobacteria 201174|Actinobacteria S Domain of unknown function (DUF5060) - - - - - - - - - - - - DUF4038,DUF5060 CMS3_k127_6055521_1 1121104.AQXH01000004_gene39 5.432e-114 374.0 COG4242@1|root,COG4242@2|Bacteria,4NHDE@976|Bacteroidetes,1IWDD@117747|Sphingobacteriia 976|Bacteroidetes PQ Peptidase family S51 - - 3.4.15.6 ko:K13282 - - R09722 RC00064,RC00141 ko00000,ko01000,ko01002 - - - Peptidase_S51 CMS3_k127_6055521_2 1121904.ARBP01000006_gene3699 3.99e-112 370.0 COG3622@1|root,COG3622@2|Bacteria,4PM6P@976|Bacteroidetes,47YPG@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_6055521_0 1121904.ARBP01000009_gene4340 1.58e-222 713.0 COG2133@1|root,COG3291@1|root,COG4654@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4654@2|Bacteria,4PNA4@976|Bacteroidetes,47YAQ@768503|Cytophagia 976|Bacteroidetes CG Glucose / Sorbosone dehydrogenase - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - CBM_6,Cytochrom_C,GSDH,PKD,ThuA CMS3_k127_6058117_3 1123057.P872_00275 4.407e-17 80.0 COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,47JDX@768503|Cytophagia 976|Bacteroidetes C Belongs to the iron ascorbate-dependent oxidoreductase family - - - - - - - - - - - - 2OG-FeII_Oxy,DIOX_N CMS3_k127_6058117_0 1124780.ANNU01000019_gene1787 1.405e-190 603.0 2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,47MEQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6058117_1 1313301.AUGC01000008_gene493 6.027e-177 563.0 2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6058117_2 1408433.JHXV01000005_gene2335 9.4e-131 443.0 COG1404@1|root,COG1404@2|Bacteria,4PI0A@976|Bacteroidetes,1IMVQ@117743|Flavobacteriia,2PBY2@246874|Cryomorphaceae 976|Bacteroidetes O Subtilase family - - - - - - - - - - - - Peptidase_S8 CMS3_k127_6073275_0 1121875.KB907548_gene1646 1.744e-141 456.0 COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,1HZK0@117743|Flavobacteriia 976|Bacteroidetes K AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_6073275_1 1121875.KB907548_gene1645 6.849e-94 313.0 COG1266@1|root,COG1266@2|Bacteria,4NGBZ@976|Bacteroidetes,1HZ6J@117743|Flavobacteriia 976|Bacteroidetes S CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_6073275_2 926549.KI421517_gene2413 2.442e-51 185.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6073681_0 1124780.ANNU01000077_gene785 4.076e-88 301.0 COG1649@1|root,COG1649@2|Bacteria,4NJ45@976|Bacteroidetes,47JSI@768503|Cytophagia 976|Bacteroidetes S Carbohydrate esterase, sialic acid-specific acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA CMS3_k127_6073766_1 313606.M23134_00145 4.078e-66 241.0 28IVH@1|root,2Z8TX@2|Bacteria,4NEEW@976|Bacteroidetes,47N52@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - DUF4350 CMS3_k127_6073766_0 485917.Phep_0237 9.767e-127 414.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPUZ@117747|Sphingobacteriia 976|Bacteroidetes S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 CMS3_k127_6073766_2 620914.JH621248_gene3189 3.221e-29 122.0 COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1HXIV@117743|Flavobacteriia,2YI62@290174|Aquimarina 976|Bacteroidetes S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 CMS3_k127_6075093_0 1121904.ARBP01000008_gene3263 2.012e-285 887.0 COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes,47JFT@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 65, N-terminal domain - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Glyco_hyd_65N_2 CMS3_k127_6075093_1 1185876.BN8_01972 4.594e-78 276.0 COG4948@1|root,COG4948@2|Bacteria,4NGZF@976|Bacteroidetes,47NF7@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - 4.2.1.68 ko:K18334 ko00051,ko01120,map00051,map01120 - R03688 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_6076131_0 269798.CHU_0908 3.791e-38 148.0 COG0750@1|root,COG0750@2|Bacteria,4NI5C@976|Bacteroidetes,47K57@768503|Cytophagia 976|Bacteroidetes M Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 CMS3_k127_6076131_1 307480.IW16_22340 6.57e-24 111.0 arCOG10603@1|root,32SV6@2|Bacteria,4NFE9@976|Bacteroidetes,1I3WY@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6076979_2 1214101.BN159_0094 2.568e-81 280.0 COG0189@1|root,COG0189@2|Bacteria 2|Bacteria HJ Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - - - - - - - - - - RimK CMS3_k127_6076979_1 760192.Halhy_6192 1.079e-219 690.0 COG1457@1|root,COG1457@2|Bacteria,4NHHC@976|Bacteroidetes 976|Bacteroidetes F Belongs to the purine-cytosine permease (2.A.39) family - - - - - - - - - - - - - CMS3_k127_6076979_4 1121904.ARBP01000005_gene4750 3.241e-05 48.0 2EN3D@1|root,33FRH@2|Bacteria,4NZ77@976|Bacteroidetes,47T85@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6076979_0 1121904.ARBP01000019_gene2780 0.0 1402.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,47M35@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6076979_3 1121904.ARBP01000019_gene2779 6.2e-20 93.0 COG4198@1|root,COG4198@2|Bacteria,4NEAX@976|Bacteroidetes,47M4K@768503|Cytophagia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like,SusD-like_2 CMS3_k127_6079852_1 1121859.KB890755_gene1292 3.554e-159 518.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47YFA@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - Laminin_G_3,PSCyt1,PSCyt2,PSD1 CMS3_k127_6079852_0 1121904.ARBP01000001_gene5847 3.503e-242 755.0 COG3119@1|root,COG3119@2|Bacteria,4PKKW@976|Bacteroidetes,47Y6A@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_6079852_2 935837.JAEK01000008_gene3348 4.548e-98 327.0 COG3618@1|root,COG3618@2|Bacteria,1URZE@1239|Firmicutes,4HAYX@91061|Bacilli,1ZG0M@1386|Bacillus 91061|Bacilli S Amidohydrolase - - - ko:K07046 ko00051,ko01120,map00051,map01120 - R10689 RC00537 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS3_k127_6079852_3 362418.IW19_06045 4.593e-66 235.0 COG0705@1|root,COG0705@2|Bacteria,4NECA@976|Bacteroidetes,1HYWY@117743|Flavobacteriia,2NSAH@237|Flavobacterium 976|Bacteroidetes S protease - - - - - - - - - - - - Rhomboid CMS3_k127_608168_2 755732.Fluta_2181 1.542e-109 361.0 COG1208@1|root,COG2905@1|root,COG1208@2|Bacteria,COG2905@2|Bacteria,4NFDB@976|Bacteroidetes,1IIX7@117743|Flavobacteriia,2PBTK@246874|Cryomorphaceae 976|Bacteroidetes M Nucleotidyl transferase gmhB - 2.7.7.71 ko:K15669 ko00540,map00540 - R09772 RC00002 ko00000,ko00001,ko01000 - - - CBS,NTP_transferase CMS3_k127_608168_4 313603.FB2170_05775 3.009e-77 267.0 COG1083@1|root,COG1083@2|Bacteria,4NJC4@976|Bacteroidetes,1IENY@117743|Flavobacteriia,2PIDV@252356|Maribacter 976|Bacteroidetes M Cytidylyltransferase neuA - 2.7.7.43 ko:K00983 ko00520,ko01100,map00520,map01100 - R01117,R04215 RC00152 ko00000,ko00001,ko01000 - - - CTP_transf_3 CMS3_k127_608168_0 1279009.ADICEAN_01122 4.062e-159 506.0 COG0451@1|root,COG0451@2|Bacteria,4NIMH@976|Bacteroidetes,47VKF@768503|Cytophagia 976|Bacteroidetes M Male sterility protein - - - - - - - - - - - - GDP_Man_Dehyd CMS3_k127_608168_1 1121011.AUCB01000002_gene380 4.705e-130 427.0 COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,1HX99@117743|Flavobacteriia,23HUI@178469|Arenibacter 976|Bacteroidetes M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 CMS3_k127_608168_5 167546.P9301_14351 8.225e-67 239.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - 3.2.1.8,3.5.1.104 ko:K01181,ko:K22278 - - - - ko00000,ko01000 - - - CBM9_1,CBM_4_9,Glyco_hydro_10,PEGA,Polysacc_deac_1,SLH CMS3_k127_608168_3 1282887.AUJG01000002_gene787 7.921e-93 311.0 COG0223@1|root,COG0223@2|Bacteria 2|Bacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N CMS3_k127_6084180_1 562970.Btus_2494 2.614e-145 467.0 COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,277YN@186823|Alicyclobacillaceae 91061|Bacilli C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_8,Nitrate_red_gam CMS3_k127_6084180_4 882083.SacmaDRAFT_1924 3.211e-58 210.0 2DPCA@1|root,331H2@2|Bacteria,2HCYY@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - CMS3_k127_6084180_2 309801.trd_0153 9.626e-138 446.0 COG1148@1|root,COG1148@2|Bacteria 2|Bacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein hdrA - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4,Fer4_6,Pyr_redox_2 CMS3_k127_6084180_0 309801.trd_0154 1.37e-185 587.0 COG2048@1|root,COG2048@2|Bacteria 2|Bacteria C Heterodisulfide reductase, subunit B - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG CMS3_k127_6084180_3 882083.SacmaDRAFT_1921 2.549e-106 349.0 COG1150@1|root,COG1150@2|Bacteria,2H2X3@201174|Actinobacteria 201174|Actinobacteria C 4Fe-4S dicluster domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03390 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4_8 CMS3_k127_6086303_0 1121859.KB890738_gene2884 3.875e-154 501.0 COG2159@1|root,COG2159@2|Bacteria,4P1JX@976|Bacteroidetes 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_6087517_2 1121904.ARBP01000029_gene2184 4.223e-58 210.0 COG4654@1|root,COG4654@2|Bacteria 2|Bacteria C Cytochrome c, class I - - - - - - - - - - - - F5_F8_type_C,PSCyt1,PSCyt2,PSD1 CMS3_k127_6087517_0 1122176.KB903587_gene4461 2.511e-231 723.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1INYZ@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.85 ko:K10217 ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00569 R02762,R03889,R05353 RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_6087517_1 760192.Halhy_3071 5.068e-64 223.0 COG1878@1|root,COG1878@2|Bacteria,4NFXM@976|Bacteroidetes 976|Bacteroidetes S Metal-dependent hydrolase - - - - - - - - - - - - Cyclase CMS3_k127_6088941_0 700598.Niako_1203 4.821e-183 600.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6088941_1 643867.Ftrac_3426 7.455e-153 501.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6110479_7 489825.LYNGBM3L_06070 4.43e-28 117.0 COG3500@1|root,COG3500@2|Bacteria,1GCWA@1117|Cyanobacteria,1HF6Y@1150|Oscillatoriales 1117|Cyanobacteria S Late control gene D protein - - - - - - - - - - - - - CMS3_k127_6110479_2 489825.LYNGBM3L_06080 2.211e-107 354.0 COG3501@1|root,COG3501@2|Bacteria,1GBZU@1117|Cyanobacteria,1HE9K@1150|Oscillatoriales 1117|Cyanobacteria S Rhs element vgr protein - - - - - - - - - - - - - CMS3_k127_6110479_8 102129.Lepto7375DRAFT_1399 2.146e-23 106.0 2FHT3@1|root,349KD@2|Bacteria,1GFCI@1117|Cyanobacteria,1HG3V@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_6110479_6 489825.LYNGBM3L_06120 4.903e-30 123.0 COG3628@1|root,COG3628@2|Bacteria,1GFKV@1117|Cyanobacteria,1HGGC@1150|Oscillatoriales 1117|Cyanobacteria S GPW Gp25 family protein - - - - - - - - - - - - - CMS3_k127_6110479_1 489825.LYNGBM3L_06130 4.87e-120 415.0 COG3299@1|root,COG3299@2|Bacteria,1GD8D@1117|Cyanobacteria,1HE16@1150|Oscillatoriales 1117|Cyanobacteria S Baseplate J-like protein - - - - - - - - - - - - Baseplate_J CMS3_k127_6110479_4 102129.Lepto7375DRAFT_1396 1.449e-57 220.0 292QY@1|root,2ZQ8Q@2|Bacteria,1GBK5@1117|Cyanobacteria,1HEN2@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_6110479_5 489825.LYNGBM3L_48710 6.146e-35 139.0 2E8EM@1|root,332T0@2|Bacteria,1GE1M@1117|Cyanobacteria,1HFPI@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_6110479_9 102129.Lepto7375DRAFT_1392 3.131e-06 58.0 299RF@1|root,2ZWTP@2|Bacteria,1GFZW@1117|Cyanobacteria,1HH1G@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_6110479_0 1121904.ARBP01000003_gene6255 2.719e-267 852.0 COG4206@1|root,COG4206@2|Bacteria,4PKFW@976|Bacteroidetes,47Y2Y@768503|Cytophagia 976|Bacteroidetes H Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3 CMS3_k127_6110479_3 1150600.ADIARSV_4304 3.363e-103 344.0 COG4992@1|root,COG4992@2|Bacteria,4NFMC@976|Bacteroidetes,1IQCC@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_6110551_1 926556.Echvi_0788 1.779e-155 503.0 COG4198@1|root,COG4198@2|Bacteria,4NFUK@976|Bacteroidetes,47MZ4@768503|Cytophagia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 CMS3_k127_6110551_0 1120968.AUBX01000014_gene2269 2.341e-235 743.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,47Y5U@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6123588_6 929562.Emtol_1110 1.748e-84 285.0 COG2010@1|root,COG2010@2|Bacteria,4PN3J@976|Bacteroidetes,47Y8S@768503|Cytophagia 976|Bacteroidetes C Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_6123588_3 313603.FB2170_04530 2.064e-145 469.0 COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia,2PGR5@252356|Maribacter 976|Bacteroidetes S Sodium Bile acid symporter family - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF CMS3_k127_6123588_5 760192.Halhy_4326 2.994e-111 383.0 COG0526@1|root,COG0526@2|Bacteria,4NKFI@976|Bacteroidetes,1IRSC@117747|Sphingobacteriia 976|Bacteroidetes CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,DUF4369,Redoxin CMS3_k127_6123588_0 1122176.KB903560_gene3555 1.555e-231 739.0 COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1IPMK@117747|Sphingobacteriia 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_6123588_1 1283300.ATXB01000002_gene2988 7.995e-205 643.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,1RP2M@1236|Gammaproteobacteria,1XGME@135618|Methylococcales 135618|Methylococcales S Mo-co oxidoreductase dimerisation domain - - - ko:K17225 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Mo-co_dimer,Oxidored_molyb CMS3_k127_6123588_9 1121904.ARBP01000005_gene4775 2.562e-29 124.0 2E0TJ@1|root,32WB7@2|Bacteria,4NTAN@976|Bacteroidetes,47RC3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6123588_4 1122176.KB903537_gene1714 7.341e-145 466.0 COG3000@1|root,COG3000@2|Bacteria,4NEYE@976|Bacteroidetes,1IU4R@117747|Sphingobacteriia 976|Bacteroidetes I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase CMS3_k127_6123588_2 1122176.KB903536_gene1789 4.68e-151 488.0 COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1ISM5@117747|Sphingobacteriia 976|Bacteroidetes O Peptidase, M28 - - - - - - - - - - - - PD40,PDZ_2,Peptidase_M28 CMS3_k127_6123588_10 1356852.N008_15160 0.0001456 54.0 COG2353@1|root,COG2356@1|root,COG3391@1|root,COG2353@2|Bacteria,COG2356@2|Bacteria,COG3391@2|Bacteria,4NZAU@976|Bacteroidetes 976|Bacteroidetes DZ YceI-like domain - - - - - - - - - - - - - CMS3_k127_6123588_8 1313421.JHBV01000035_gene2550 1.56e-37 150.0 COG1309@1|root,COG1309@2|Bacteria,4NMW9@976|Bacteroidetes,1ISMH@117747|Sphingobacteriia 976|Bacteroidetes K regulatory protein TetR - - - - - - - - - - - - TetR_N CMS3_k127_6123588_7 761193.Runsl_2021 1.102e-75 259.0 COG5434@1|root,COG5434@2|Bacteria,4NE9Y@976|Bacteroidetes,47KM6@768503|Cytophagia 976|Bacteroidetes M Periplasmic copper-binding protein (NosD) - - - - - - - - - - - - Beta_helix CMS3_k127_6139385_3 760192.Halhy_5387 0.0001757 51.0 COG0840@1|root,COG0840@2|Bacteria 2|Bacteria NT transmembrane signaling receptor activity - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - - CMS3_k127_6139385_1 1121912.AUHD01000001_gene2678 2.059e-86 293.0 COG2819@1|root,COG2819@2|Bacteria,4NH6C@976|Bacteroidetes,1HZPM@117743|Flavobacteriia 976|Bacteroidetes S Carbohydrate esterase - - - - - - - - - - - - Esterase CMS3_k127_6139385_0 929703.KE386491_gene2739 1.929e-148 484.0 COG0260@1|root,COG0260@2|Bacteria,4NDWT@976|Bacteroidetes,47KV8@768503|Cytophagia 976|Bacteroidetes E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N CMS3_k127_6139385_2 1392490.JHZX01000001_gene3348 4.331e-69 239.0 COG1181@1|root,COG1181@2|Bacteria,4NGM6@976|Bacteroidetes,1I09J@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the D-alanine--D-alanine ligase family - - - - - - - - - - - - ATP-grasp_4 CMS3_k127_6142260_1 616991.JPOO01000001_gene2919 2.678e-68 234.0 COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,1HXBT@117743|Flavobacteriia,23I28@178469|Arenibacter 976|Bacteroidetes Q BAAT / Acyl-CoA thioester hydrolase C terminal - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH CMS3_k127_6142260_0 1121904.ARBP01000029_gene2150 2.064e-235 772.0 COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47JBS@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_6157695_1 880070.Cycma_4697 1.753e-22 99.0 COG0436@1|root,COG0436@2|Bacteria,4NEN3@976|Bacteroidetes,47MR5@768503|Cytophagia 976|Bacteroidetes E RagB SusD - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_6157695_0 880070.Cycma_4698 5.12e-315 983.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,47NSM@768503|Cytophagia 976|Bacteroidetes P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6157695_2 504472.Slin_6609 9.586e-07 58.0 COG1595@1|root,COG1595@2|Bacteria,4NP0R@976|Bacteroidetes,47Q39@768503|Cytophagia 976|Bacteroidetes K RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6158798_4 1123037.AUDE01000013_gene546 1.647e-13 76.0 COG0160@1|root,COG2334@1|root,COG0160@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1HZ97@117743|Flavobacteriia 976|Bacteroidetes E Phosphotransferase enzyme family - - - - - - - - - - - - APH,Aminotran_3,Peptidase_M23 CMS3_k127_6158798_0 313606.M23134_08044 8.598e-69 253.0 COG0515@1|root,COG0515@2|Bacteria 313606.M23134_08044|- KLT protein kinase activity - - - - - - - - - - - - - CMS3_k127_6158798_1 1121904.ARBP01000003_gene6331 1.204e-50 205.0 COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47N72@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_6158798_2 388413.ALPR1_01095 1.638e-28 134.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - AraC_binding,HTH_18 CMS3_k127_6158798_5 1270193.JARP01000002_gene409 7.489e-10 71.0 29VY4@1|root,30HG7@2|Bacteria,4NNWV@976|Bacteroidetes,1I21U@117743|Flavobacteriia,2NUC7@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6158798_3 700598.Niako_3294 1.993e-18 90.0 2DBIE@1|root,32TXH@2|Bacteria,4NSJE@976|Bacteroidetes,1ITSC@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6165142_7 1173024.KI912149_gene5564 4.778e-54 201.0 COG2244@1|root,COG2244@2|Bacteria,1G3GP@1117|Cyanobacteria,1JK2C@1189|Stigonemataceae 1117|Cyanobacteria S Polysaccharide biosynthesis protein - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt_3,Polysacc_synt_C CMS3_k127_6165142_1 760192.Halhy_2893 2.286e-85 295.0 COG0438@1|root,COG0438@2|Bacteria,4PG4H@976|Bacteroidetes,1IT1I@117747|Sphingobacteriia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_6165142_0 313612.L8106_06334 3.582e-98 334.0 COG0438@1|root,COG0438@2|Bacteria,1G0EX@1117|Cyanobacteria,1H9C2@1150|Oscillatoriales 1117|Cyanobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 CMS3_k127_6165142_4 762968.HMPREF9441_00402 4.424e-77 271.0 COG0438@1|root,COG0438@2|Bacteria,4NGSA@976|Bacteroidetes,2FPXN@200643|Bacteroidia 976|Bacteroidetes M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_6165142_5 471870.BACINT_03054 3.983e-74 266.0 COG0451@1|root,COG0451@2|Bacteria,4PHT4@976|Bacteroidetes,2FNQG@200643|Bacteroidia,4APQW@815|Bacteroidaceae 976|Bacteroidetes M COG0451 Nucleoside-diphosphate-sugar - - 5.1.3.26 ko:K19997 - - - - ko00000,ko01000 - - - Epimerase CMS3_k127_6165142_3 1121904.ARBP01000006_gene3886 4.576e-78 268.0 COG1922@1|root,COG1922@2|Bacteria,4NJGT@976|Bacteroidetes,47NEK@768503|Cytophagia 976|Bacteroidetes M Belongs to the glycosyltransferase 26 family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB CMS3_k127_6165142_2 435591.BDI_0654 2.495e-80 286.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,4NER4@976|Bacteroidetes,2FNC2@200643|Bacteroidia,22VY7@171551|Porphyromonadaceae 976|Bacteroidetes M CoA-binding domain wcaJ_2 - 2.7.8.6 ko:K00996,ko:K03606 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 CMS3_k127_6165142_6 1279009.ADICEAN_00921 4.653e-64 228.0 COG1596@1|root,COG1596@2|Bacteria,4NQV1@976|Bacteroidetes,47VPS@768503|Cytophagia 976|Bacteroidetes M Polysaccharide biosynthesis/export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export CMS3_k127_6165142_8 1123277.KB893175_gene1309 5.249e-12 72.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz CMS3_k127_616727_3 926549.KI421517_gene1004 4.962e-13 72.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47R8S@768503|Cytophagia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_616727_0 929556.Solca_2394 3.308e-105 365.0 COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,4NEVN@976|Bacteroidetes,1IS6A@117747|Sphingobacteriia 976|Bacteroidetes T PFAM Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - Guanylate_cyc,Response_reg,TPR_12,TPR_8 CMS3_k127_616727_2 1121957.ATVL01000006_gene2992 7.34e-16 82.0 2ESFM@1|root,329J8@2|Bacteria,4P7DE@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_616727_1 1236959.BAMT01000002_gene2097 4.18e-31 123.0 COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,2VU3I@28216|Betaproteobacteria,2KN4F@206350|Nitrosomonadales 206350|Nitrosomonadales J PFAM ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 CMS3_k127_6175064_5 1174528.JH992898_gene4644 3.109e-09 62.0 COG1572@1|root,COG4675@1|root,COG1572@2|Bacteria,COG4675@2|Bacteria,1G8V2@1117|Cyanobacteria 1117|Cyanobacteria S tail collar domain protein - - - - - - - - - - - - Laminin_G_3 CMS3_k127_6175064_3 1469557.JSWF01000015_gene2720 1.081e-25 120.0 COG1520@1|root,COG1520@2|Bacteria,4NZRS@976|Bacteroidetes 976|Bacteroidetes S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - CMS3_k127_6175064_0 1121904.ARBP01000003_gene6499 5.616e-201 631.0 COG0673@1|root,COG0673@2|Bacteria,4NFMS@976|Bacteroidetes,47K95@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_6175064_1 1121904.ARBP01000003_gene6500 3.017e-187 589.0 COG1082@1|root,COG1082@2|Bacteria,4NGBE@976|Bacteroidetes,47M7V@768503|Cytophagia 976|Bacteroidetes G AP endonuclease - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N CMS3_k127_6175064_4 1237149.C900_01360 8.204e-25 113.0 COG2133@1|root,COG4654@1|root,COG2133@2|Bacteria,COG4654@2|Bacteria,4NEMM@976|Bacteroidetes,47KXP@768503|Cytophagia 976|Bacteroidetes CG PFAM Cytochrome c, class I - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C,DUF1080,PA14 CMS3_k127_6175064_2 760192.Halhy_3481 4.725e-30 119.0 COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes 976|Bacteroidetes G Pfam Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_6175300_0 1121896.JMLU01000010_gene1356 9.876e-189 606.0 COG1200@1|root,COG1200@2|Bacteria,4NDZV@976|Bacteroidetes,1HX1Z@117743|Flavobacteriia,2NT3Q@237|Flavobacterium 976|Bacteroidetes L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge CMS3_k127_6175300_7 1321779.HMPREF1984_00454 8.603e-12 78.0 COG0683@1|root,COG0683@2|Bacteria,3796J@32066|Fusobacteria 32066|Fusobacteria E Psort location Periplasmic, score - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS3_k127_6175300_3 1237149.C900_04340 1.632e-76 267.0 COG1266@1|root,COG1266@2|Bacteria,4NJAV@976|Bacteroidetes,47M12@768503|Cytophagia 976|Bacteroidetes S CAAX protease self-immunity - - - - - - - - - - - - Abi CMS3_k127_6175300_5 316274.Haur_0953 1.898e-44 167.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase VY92_01935 - - - - - - - - - - - Acetyltransf_1 CMS3_k127_6175300_2 1048983.EL17_08655 9.144e-91 306.0 COG1968@1|root,COG1968@2|Bacteria,4NGIZ@976|Bacteroidetes,47KGZ@768503|Cytophagia 976|Bacteroidetes V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA CMS3_k127_6175300_8 879243.Poras_1638 7.556e-06 53.0 2E6VD@1|root,331EZ@2|Bacteria,4NUSW@976|Bacteroidetes,2FTVZ@200643|Bacteroidia,22YX4@171551|Porphyromonadaceae 976|Bacteroidetes S Protein of unknown function (DUF3098) fjo13 - - - - - - - - - - - DUF3098 CMS3_k127_6175300_6 762903.Pedsa_0247 1.156e-39 159.0 COG2177@1|root,COG2177@2|Bacteria,4NH05@976|Bacteroidetes,1INNN@117747|Sphingobacteriia 976|Bacteroidetes D Belongs to the ABC-4 integral membrane protein family. FtsX subfamily ftsX GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX CMS3_k127_6175300_1 391587.KAOT1_19847 1.271e-91 308.0 COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,1HXEP@117743|Flavobacteriia 976|Bacteroidetes M mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix CMS3_k127_6175300_4 1123277.KB893174_gene5927 1.58e-75 269.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,47XEG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - His_kinase,Reg_prop,Y_Y_Y CMS3_k127_6177038_6 929556.Solca_1727 1.095e-111 376.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IQYT@117747|Sphingobacteriia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS3_k127_6177038_12 1122176.KB903545_gene827 2.18e-54 202.0 COG0860@1|root,COG0860@2|Bacteria,4NR00@976|Bacteroidetes 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 CMS3_k127_6177038_11 1305737.JAFX01000001_gene2267 4.108e-55 198.0 COG0694@1|root,COG0694@2|Bacteria,4NG0Q@976|Bacteroidetes,47PV2@768503|Cytophagia 976|Bacteroidetes O PFAM Scaffold protein Nfu NifU N terminal - - - - - - - - - - - - Nfu_N,NifU CMS3_k127_6177038_14 1121957.ATVL01000010_gene471 1.603e-06 59.0 28Q02@1|root,2ZCJ2@2|Bacteria,4NSAI@976|Bacteroidetes,47Q5U@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 CMS3_k127_6177038_3 926549.KI421517_gene2288 7.63e-130 422.0 COG1482@1|root,COG1482@2|Bacteria,4NF9A@976|Bacteroidetes,47K7F@768503|Cytophagia 976|Bacteroidetes G Phosphomannose isomerase type I manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - - PMI_typeI CMS3_k127_6177038_7 1313421.JHBV01000029_gene1973 2.064e-81 282.0 COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes,1IT5C@117747|Sphingobacteriia 976|Bacteroidetes S nucleotidyltransferase activity - - - - - - - - - - - - NTP_transf_2 CMS3_k127_6177038_0 1313421.JHBV01000029_gene1972 3.513e-193 614.0 COG1032@1|root,COG1032@2|Bacteria,4NETM@976|Bacteroidetes,1IQPV@117747|Sphingobacteriia 976|Bacteroidetes C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM CMS3_k127_6177038_8 1237149.C900_03020 3.099e-62 223.0 COG0500@1|root,COG2226@2|Bacteria,4NICK@976|Bacteroidetes 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 CMS3_k127_6177038_1 1237149.C900_03019 6.036e-187 595.0 COG1032@1|root,COG1032@2|Bacteria,4NKFV@976|Bacteroidetes 976|Bacteroidetes C Radical SAM - - - - - - - - - - - - B12-binding,Radical_SAM CMS3_k127_6177038_10 945713.IALB_2764 2.504e-56 205.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase ermC - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran CMS3_k127_6177038_9 1265503.KB905167_gene1708 4.118e-57 215.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 CMS3_k127_6177038_5 929562.Emtol_2016 3.389e-116 386.0 COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,47M8R@768503|Cytophagia 976|Bacteroidetes H Molybdenum cofactor synthesis domain protein moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N CMS3_k127_6177038_13 1403313.AXBR01000008_gene659 3.462e-13 79.0 COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HK7U@91061|Bacilli,1ZDH4@1386|Bacillus 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase CMS3_k127_6177038_4 760192.Halhy_1976 1.121e-127 415.0 COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,1IPUJ@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM CMS3_k127_6177038_2 616991.JPOO01000003_gene867 4.379e-174 553.0 COG0243@1|root,COG0243@2|Bacteria,4NF6W@976|Bacteroidetes,1HZBZ@117743|Flavobacteriia,23GK7@178469|Arenibacter 976|Bacteroidetes C Molydopterin dinucleotide binding domain fdhF - - - - - - - - - - - Molybdopterin,Molydop_binding CMS3_k127_6180610_0 1237149.C900_00706 1.39e-104 355.0 COG0323@1|root,COG0323@2|Bacteria,4NDWJ@976|Bacteroidetes,47KZU@768503|Cytophagia 976|Bacteroidetes L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C CMS3_k127_6180610_1 649349.Lbys_1891 2.504e-24 111.0 COG0705@1|root,COG0705@2|Bacteria,4NIYR@976|Bacteroidetes,47PBZ@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - 3.4.21.105 ko:K09650 - - - - ko00000,ko01000,ko01002,ko03029 - - - Rhomboid CMS3_k127_6180610_2 1120968.AUBX01000016_gene1735 1.21e-07 62.0 COG0705@1|root,COG0705@2|Bacteria,4NGVJ@976|Bacteroidetes,47JAM@768503|Cytophagia 976|Bacteroidetes S PFAM Rhomboid family - - - - - - - - - - - - Rhomboid CMS3_k127_6191486_4 485918.Cpin_1026 3.784e-70 247.0 COG1807@1|root,COG1807@2|Bacteria,4NEU7@976|Bacteroidetes,1IR4N@117747|Sphingobacteriia 976|Bacteroidetes M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - - - - - - - - - - PMT_2 CMS3_k127_6191486_2 671143.DAMO_0703 1.414e-102 341.0 COG2230@1|root,COG2230@2|Bacteria 2|Bacteria M cyclopropane-fatty-acyl-phospholipid synthase - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249 2.1.1.254,2.1.1.295,2.1.1.79,2.7.11.1 ko:K00574,ko:K07154,ko:K14369,ko:K15257,ko:K18534 ko00130,ko00522,ko01100,ko01110,ko01130,map00130,map00522,map01100,map01110,map01130 M00112,M00774 R05520,R05532,R07501,R10709,R10710 RC00003,RC01324,RC01662 ko00000,ko00001,ko00002,ko01000,ko01001,ko01008,ko02048,ko03016 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 CMS3_k127_6191486_0 1121904.ARBP01000006_gene3917 6.652e-149 475.0 COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,47NC5@768503|Cytophagia 976|Bacteroidetes Q Phytanoyl-CoA dioxygenase (PhyH) - - - - - - - - - - - - PhyH CMS3_k127_6191486_1 1121904.ARBP01000019_gene2742 1.033e-139 451.0 COG1063@1|root,COG1063@2|Bacteria,4NHCK@976|Bacteroidetes,47K5V@768503|Cytophagia 976|Bacteroidetes E alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS3_k127_6191486_6 1121898.Q766_00410 2.379e-35 145.0 COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,1HYAY@117743|Flavobacteriia,2NTBS@237|Flavobacterium 976|Bacteroidetes T Universal stress protein uspA - - - - - - - - - - - DUF2007,Usp CMS3_k127_6191486_5 760192.Halhy_1878 2.461e-52 198.0 COG3509@1|root,COG3509@2|Bacteria 2|Bacteria Q xylan catabolic process - - - ko:K03932 - - - - ko00000 - CE1 - Esterase,Esterase_phd CMS3_k127_6191486_3 1380384.JADN01000008_gene1302 9.669e-86 291.0 2DBMF@1|root,2Z9YG@2|Bacteria,4NPRW@976|Bacteroidetes,1I1PP@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6195079_1 886379.AEWI01000018_gene1304 1.93e-166 537.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,2FMUA@200643|Bacteroidia,3XJ0M@558415|Marinilabiliaceae 976|Bacteroidetes O Trypsin htrA - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 CMS3_k127_6195079_4 1122194.AUHU01000010_gene3123 1.887e-73 254.0 COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,466MF@72275|Alteromonadaceae 1236|Gammaproteobacteria F NUDIX domain nuhA - - - - - - - - - - - NUDIX CMS3_k127_6195079_0 1121904.ARBP01000006_gene3853 0.0 1429.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,47ME8@768503|Cytophagia 976|Bacteroidetes EF PFAM Carbamoyl-phosphate synthase L chain, ATP binding carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS CMS3_k127_6195079_5 1353276.JADR01000008_gene891 2.6e-69 243.0 COG1752@1|root,COG1752@2|Bacteria,4NERH@976|Bacteroidetes,1HZ38@117743|Flavobacteriia 976|Bacteroidetes S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin CMS3_k127_6195079_2 1349785.BAUG01000018_gene1321 1.602e-156 500.0 COG0809@1|root,COG0809@2|Bacteria,4NF2T@976|Bacteroidetes,1HYMK@117743|Flavobacteriia 976|Bacteroidetes J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth CMS3_k127_6195079_6 1121373.KB903663_gene1076 5.297e-46 175.0 COG1211@1|root,COG1211@2|Bacteria,4NMB5@976|Bacteroidetes,47P6K@768503|Cytophagia 976|Bacteroidetes I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD CMS3_k127_6195079_3 1121870.AUAA01000081_gene727 3.242e-114 382.0 COG2189@1|root,COG2189@2|Bacteria 2|Bacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase CMS3_k127_6195079_8 1423790.BN53_05445 1.22e-06 61.0 COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,4HBP1@91061|Bacilli,3F504@33958|Lactobacillaceae 91061|Bacilli L DNA methylase mod - 2.1.1.72 ko:K00571,ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,TypeIII_RM_meth CMS3_k127_6231466_0 714943.Mucpa_3489 2.799e-103 377.0 COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1INZH@117747|Sphingobacteriia 976|Bacteroidetes T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zraS_1 - - - - - - - - - - - HATPase_c,HisKA CMS3_k127_6231466_1 945713.IALB_1764 3.887e-64 235.0 COG5448@1|root,COG5448@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2460 CMS3_k127_6235396_1 1047013.AQSP01000070_gene34 1.695e-148 497.0 COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,2NNZT@2323|unclassified Bacteria 2|Bacteria T Two component regulator propeller pdtaS - 2.7.13.3 ko:K00936 - M00839 - - ko00000,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,Reg_prop,Y_Y_Y CMS3_k127_6235396_8 929703.KE386491_gene898 0.0005282 50.0 COG0457@1|root,COG0457@2|Bacteria,4NJ7X@976|Bacteroidetes,47NJZ@768503|Cytophagia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_8 CMS3_k127_6235396_0 983917.RGE_14420 2.54e-163 523.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VQB6@28216|Betaproteobacteria,1KNAK@119065|unclassified Burkholderiales 28216|Betaproteobacteria E Cys/Met metabolism PLP-dependent enzyme - - 4.4.1.11 ko:K01761 ko00270,ko00450,map00270,map00450 - R00654,R04770 RC00196,RC00348,RC01209,RC01210 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_6235396_5 1107311.Q767_13765 2.811e-73 254.0 29R44@1|root,30C5C@2|Bacteria,4NN15@976|Bacteroidetes,1I5DW@117743|Flavobacteriia,2NTM8@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6235396_2 1249975.JQLP01000005_gene2430 2.766e-124 401.0 COG1432@1|root,COG1432@2|Bacteria,4NGF1@976|Bacteroidetes,1HWKN@117743|Flavobacteriia,2P68P@244698|Gillisia 976|Bacteroidetes S OST-HTH/LOTUS domain - - - - - - - - - - - - NYN,OST-HTH CMS3_k127_6235396_3 1313421.JHBV01000041_gene3551 1.84e-83 283.0 COG0500@1|root,COG2226@2|Bacteria,4NG68@976|Bacteroidetes,1IRA0@117747|Sphingobacteriia 976|Bacteroidetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 CMS3_k127_6235396_6 445961.IW15_05340 1.394e-21 97.0 2CVTP@1|root,32SY9@2|Bacteria,4NUEJ@976|Bacteroidetes,1I4ZN@117743|Flavobacteriia,3ZRT9@59732|Chryseobacterium 976|Bacteroidetes S Protein of unknown function (DUF1203) - - - - - - - - - - - - DUF1203 CMS3_k127_6235396_4 742766.HMPREF9455_04078 3.229e-83 284.0 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,4NFYC@976|Bacteroidetes,2FP18@200643|Bacteroidia,22YIW@171551|Porphyromonadaceae 976|Bacteroidetes L 6-O-methylguanine DNA methyltransferase, DNA binding domain ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,HTH_18,Methyltransf_1N CMS3_k127_6235396_7 929556.Solca_0458 7.761e-16 78.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - - - - - - - - - - - HEAT_2 CMS3_k127_6239221_4 655815.ZPR_2921 3.935e-38 144.0 COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1HWQ1@117743|Flavobacteriia 976|Bacteroidetes J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans CMS3_k127_6239221_1 1120970.AUBZ01000028_gene1640 1.053e-93 314.0 COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,1S0A5@1236|Gammaproteobacteria 1236|Gammaproteobacteria GK ROK family - - 2.7.1.63 ko:K00886 ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R02187,R02189 RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK CMS3_k127_6239221_0 1313421.JHBV01000039_gene2760 3.475e-127 435.0 COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes 976|Bacteroidetes Q PFAM FG-GAP repeat - - - - - - - - - - - - VCBS CMS3_k127_6239221_2 313606.M23134_06584 5.061e-76 266.0 COG1647@1|root,COG1647@2|Bacteria,4NHPY@976|Bacteroidetes,47JR1@768503|Cytophagia 976|Bacteroidetes E Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,BAAT_C,Hydrolase_4 CMS3_k127_6239221_3 1121904.ARBP01000002_gene7106 1.012e-54 197.0 COG4870@1|root,COG4870@2|Bacteria,4NGK1@976|Bacteroidetes,47MRK@768503|Cytophagia 976|Bacteroidetes O Papain family cysteine protease - - - - - - - - - - - - DUF4384,Peptidase_C1 CMS3_k127_6240615_2 1089547.KB913013_gene3259 1.473e-127 418.0 COG1373@1|root,COG1373@2|Bacteria,4NEMX@976|Bacteroidetes,47MKR@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_6240615_1 1396418.BATQ01000133_gene4068 6.506e-255 792.0 COG4102@1|root,COG4102@2|Bacteria,46UTC@74201|Verrucomicrobia,2IV1U@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_6240615_0 1396418.BATQ01000136_gene3672 7.106e-287 904.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 CMS3_k127_6240615_4 985255.APHJ01000054_gene1998 5.091e-116 379.0 COG1741@1|root,COG1741@2|Bacteria,4NFZD@976|Bacteroidetes,1HXX4@117743|Flavobacteriia,2P6VW@244698|Gillisia 976|Bacteroidetes S Pirin C-terminal cupin domain - - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C CMS3_k127_6240615_6 1170562.Cal6303_3144 1.929e-39 156.0 COG4636@1|root,COG4636@2|Bacteria,1G453@1117|Cyanobacteria,1HKJZ@1161|Nostocales 1117|Cyanobacteria S Putative restriction endonuclease - - - - - - - - - - - - Uma2 CMS3_k127_6240615_5 595460.RRSWK_02786 2.642e-79 276.0 COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes 203682|Planctomycetes G ABC-type sugar transport system periplasmic component - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 CMS3_k127_6240615_3 886293.Sinac_2682 5.826e-117 389.0 COG1129@1|root,COG1129@2|Bacteria,2IXQH@203682|Planctomycetes 203682|Planctomycetes G transport system, ATPase - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran CMS3_k127_6241071_0 1267211.KI669560_gene1286 1.766e-221 701.0 COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1INRQ@117747|Sphingobacteriia 976|Bacteroidetes S glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C CMS3_k127_6241071_1 1250232.JQNJ01000001_gene2678 3.928e-70 243.0 COG0664@1|root,COG0664@2|Bacteria,4NJRX@976|Bacteroidetes,1IIWQ@117743|Flavobacteriia 976|Bacteroidetes T Cyclic nucleotide-monophosphate binding domain - - - - - - - - - - - - cNMP_binding CMS3_k127_6241071_2 761193.Runsl_4075 7.097e-59 211.0 COG2010@1|root,COG2010@2|Bacteria,4NQXA@976|Bacteroidetes,47QS4@768503|Cytophagia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS3_k127_62457_1 870187.Thini_2445 4.11e-26 123.0 COG0457@1|root,COG0498@1|root,COG1192@1|root,COG4995@1|root,COG0457@2|Bacteria,COG0498@2|Bacteria,COG1192@2|Bacteria,COG4995@2|Bacteria,1ND01@1224|Proteobacteria,1SXEZ@1236|Gammaproteobacteria,4639I@72273|Thiotrichales 72273|Thiotrichales DE Tetratricopeptide repeats - - - - - - - - - - - - CHAT,NB-ARC,TIR_2,TPR_12 CMS3_k127_62457_0 760192.Halhy_2578 6.527e-225 722.0 COG1629@1|root,COG4772@1|root,COG1629@2|Bacteria,COG4772@2|Bacteria,4P4MW@976|Bacteroidetes,1IRE6@117747|Sphingobacteriia 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug CMS3_k127_62457_2 1380390.JIAT01000012_gene3004 9.406e-12 76.0 COG2334@1|root,COG2334@2|Bacteria 2|Bacteria S homoserine kinase activity - - - - - - - - - - - - APH,EcKinase CMS3_k127_6250211_0 1121904.ARBP01000012_gene1348 1.065e-186 589.0 COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,47JQD@768503|Cytophagia 976|Bacteroidetes I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N CMS3_k127_6250211_1 929556.Solca_3126 4.699e-145 471.0 COG0508@1|root,COG0508@2|Bacteria,4NF33@976|Bacteroidetes,1IP4Q@117747|Sphingobacteriia 976|Bacteroidetes C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS3_k127_6250211_4 1408424.JHYI01000012_gene2350 5.566e-17 87.0 COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMNR@91061|Bacilli,1ZHWU@1386|Bacillus 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ CMS3_k127_6250211_5 452637.Oter_1694 3.216e-16 85.0 2BWTE@1|root,330HW@2|Bacteria,46XUB@74201|Verrucomicrobia,3K86Z@414999|Opitutae 414999|Opitutae S Protein of unknown function (DUF2937) - - - - - - - - - - - - DUF2937 CMS3_k127_6250211_3 502025.Hoch_3589 7.73e-47 173.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42RY9@68525|delta/epsilon subdivisions,2WW61@28221|Deltaproteobacteria,2Z2RX@29|Myxococcales 28221|Deltaproteobacteria T Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc CMS3_k127_6250211_2 983548.Krodi_0610 2.704e-106 359.0 COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,1HWTF@117743|Flavobacteriia,37EA8@326319|Dokdonia 976|Bacteroidetes E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 CMS3_k127_6251029_0 1121904.ARBP01000014_gene137 3.388e-127 415.0 COG3802@1|root,COG3802@2|Bacteria,4NGIM@976|Bacteroidetes,47TKS@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6251029_1 1121904.ARBP01000006_gene3919 3.198e-115 377.0 COG0627@1|root,COG0627@2|Bacteria,4NGI8@976|Bacteroidetes,47MS4@768503|Cytophagia 976|Bacteroidetes S Putative esterase xynC - - - - - - - - - - - Esterase CMS3_k127_6251029_2 1347342.BN863_21030 2.756e-96 317.0 COG1062@1|root,COG1062@2|Bacteria,4NF83@976|Bacteroidetes,1HY5N@117743|Flavobacteriia 976|Bacteroidetes C Alcohol dehydrogenase GroES-like domain - - 1.1.1.1,1.1.1.284 ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS3_k127_625309_0 929556.Solca_3302 2.107e-37 156.0 COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,1IQQP@117747|Sphingobacteriia 976|Bacteroidetes S Tetratricopeptide repeat protein sprE - - - - - - - - - - - TPR_16,TPR_6,TPR_8 CMS3_k127_625309_1 980584.AFPB01000124_gene2384 8.191e-37 151.0 COG0739@1|root,COG0739@2|Bacteria,4NFZN@976|Bacteroidetes,1HXBC@117743|Flavobacteriia,4070Y@61432|unclassified Flavobacteriaceae 976|Bacteroidetes M Peptidase family M23 nlpD_1 - - - - - - - - - - - Peptidase_M23 CMS3_k127_625309_2 313595.P700755_001994 2.186e-21 100.0 COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1I47M@117743|Flavobacteriia,4C3SE@83612|Psychroflexus 976|Bacteroidetes M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin CMS3_k127_625309_3 1296990.H845_3184 5.43e-05 48.0 COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria,2JTVG@204441|Rhodospirillales 204441|Rhodospirillales S function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 CMS3_k127_625309_4 1121912.AUHD01000008_gene135 0.0001254 46.0 COG0356@1|root,COG0356@2|Bacteria,4NEPK@976|Bacteroidetes,1HX71@117743|Flavobacteriia 976|Bacteroidetes C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A CMS3_k127_6253601_2 313606.M23134_06279 2.507e-65 237.0 COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase M1, membrane alanine aminopeptidase - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 CMS3_k127_6253601_3 504487.JCM19302_3465 2.458e-60 223.0 COG0242@1|root,COG0242@2|Bacteria,4NPNS@976|Bacteroidetes,1I2ND@117743|Flavobacteriia 976|Bacteroidetes J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - DUF1684,Pep_deformylase CMS3_k127_6253601_4 1121904.ARBP01000001_gene5629 1.176e-56 208.0 29D4N@1|root,3002P@2|Bacteria,4NPSH@976|Bacteroidetes,47Q5V@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_6253601_0 1121904.ARBP01000001_gene5628 1.09e-255 813.0 COG1629@1|root,COG4771@2|Bacteria,4NEBC@976|Bacteroidetes,47N17@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6253601_5 485918.Cpin_4714 7.054e-39 151.0 COG1430@1|root,COG1430@2|Bacteria,4NQ5G@976|Bacteroidetes,1IYGP@117747|Sphingobacteriia 976|Bacteroidetes S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 CMS3_k127_6253601_1 1120966.AUBU01000012_gene67 1.464e-145 477.0 COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47JPK@768503|Cytophagia 976|Bacteroidetes S Sortilin, neurotensin receptor 3, - - - - - - - - - - - - BNR_6,Sortilin-Vps10 CMS3_k127_6254440_0 1273538.G159_04955 1.061e-115 381.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26E77@186818|Planococcaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 CMS3_k127_6254440_1 1273538.G159_02260 2.767e-115 379.0 COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,26I9G@186818|Planococcaceae 91061|Bacilli C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 CMS3_k127_6254440_4 1348338.ADILRU_2176 5.834e-17 83.0 COG2261@1|root,COG2261@2|Bacteria,2GQR5@201174|Actinobacteria,4FQ3U@85023|Microbacteriaceae 201174|Actinobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc CMS3_k127_6254440_3 388413.ALPR1_18218 1.865e-42 160.0 COG0657@1|root,COG0657@2|Bacteria,4NUK2@976|Bacteroidetes,47VEK@768503|Cytophagia 976|Bacteroidetes I acetylesterase activity - - - - - - - - - - - - DUF4440 CMS3_k127_6254440_2 1123248.KB893381_gene962 5.062e-45 169.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4P2AE@976|Bacteroidetes 976|Bacteroidetes C E-Z type HEAT repeats - - - - - - - - - - - - Cytochrom_C,HEAT_2 CMS3_k127_6264526_2 1121904.ARBP01000015_gene179 1.532e-132 437.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6264526_0 1237149.C900_00082 4.131e-173 554.0 COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,47JF9@768503|Cytophagia 976|Bacteroidetes T two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat CMS3_k127_6264526_3 313606.M23134_07782 3.354e-86 301.0 COG5000@1|root,COG5000@2|Bacteria,4NEWF@976|Bacteroidetes,47JZG@768503|Cytophagia 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c CMS3_k127_6264526_1 761193.Runsl_0427 3.406e-138 452.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47NEI@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6275881_0 234267.Acid_0469 7.644e-187 591.0 COG1506@1|root,COG1506@2|Bacteria,3Y3DT@57723|Acidobacteria 57723|Acidobacteria E peptidase S9B dipeptidylpeptidase IV domain protein - - - - - - - - - - - - DPPIV_N,Peptidase_S9 CMS3_k127_6275881_1 1121904.ARBP01000001_gene5773 5.895e-178 568.0 COG3875@1|root,COG3875@2|Bacteria 2|Bacteria S lactate racemase activity larA - 5.1.2.1 ko:K22373 ko00620,map00620 - R01450 RC00519 ko00000,ko00001,ko01000 - - - DUF2088 CMS3_k127_6275881_2 391603.FBALC1_11487 9.233e-19 89.0 COG2159@1|root,COG2159@2|Bacteria,4P1JX@976|Bacteroidetes,1I7FR@117743|Flavobacteriia 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_6282652_3 1121011.AUCB01000065_gene3235 4.242e-34 134.0 COG1409@1|root,COG1409@2|Bacteria,4NI6R@976|Bacteroidetes,1III2@117743|Flavobacteriia,23IB3@178469|Arenibacter 976|Bacteroidetes S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos CMS3_k127_6282652_1 313603.FB2170_09416 2.264e-58 209.0 COG0708@1|root,COG0708@2|Bacteria,4NGD8@976|Bacteroidetes,1HXFS@117743|Flavobacteriia 976|Bacteroidetes L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos,Laminin_G_3 CMS3_k127_6282652_0 649349.Lbys_0715 1.276e-87 301.0 COG0793@1|root,COG0793@2|Bacteria,4NFEN@976|Bacteroidetes,47PTG@768503|Cytophagia 976|Bacteroidetes M PFAM Peptidase family S41 - - - - - - - - - - - - Peptidase_S41,Tricorn_C1 CMS3_k127_6282652_5 880070.Cycma_4430 2.447e-05 55.0 2DWPY@1|root,32V1Y@2|Bacteria,4NU0T@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6282652_4 498211.CJA_3705 3.255e-17 89.0 COG2207@1|root,COG2207@2|Bacteria,1P4M5@1224|Proteobacteria,1SSHJ@1236|Gammaproteobacteria,1FGK9@10|Cellvibrio 1236|Gammaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_6282652_2 234267.Acid_7572 2.128e-36 153.0 COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PD40,Pkinase,WD40 CMS3_k127_6298547_4 504472.Slin_1529 2.265e-07 54.0 COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,47MRG@768503|Cytophagia 976|Bacteroidetes I Carboxylesterase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase CMS3_k127_6298547_6 761193.Runsl_4248 5.778e-06 50.0 COG0657@1|root,COG0657@2|Bacteria,4NIQ0@976|Bacteroidetes,47JK6@768503|Cytophagia 976|Bacteroidetes I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 CMS3_k127_6298547_5 929562.Emtol_3171 1.495e-06 49.0 COG0657@1|root,COG0657@2|Bacteria,4NIQ0@976|Bacteroidetes,47JK6@768503|Cytophagia 976|Bacteroidetes I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 CMS3_k127_6298547_2 670487.Ocepr_0357 6.957e-46 170.0 COG0517@1|root,COG0517@2|Bacteria,1WNHR@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - - - - - - - - - - CBS CMS3_k127_6298547_0 1123277.KB893185_gene2966 3.336e-217 676.0 COG0620@1|root,COG0620@2|Bacteria,4NJAH@976|Bacteroidetes,47MCD@768503|Cytophagia 976|Bacteroidetes E PFAM Methionine synthase vitamin-B12 independent - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS3_k127_6298547_1 504472.Slin_1556 7.442e-195 616.0 COG0477@1|root,COG2814@2|Bacteria,4NI75@976|Bacteroidetes,47M13@768503|Cytophagia 976|Bacteroidetes EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,MFS_4,Sugar_tr CMS3_k127_6298547_3 760192.Halhy_0463 5.14e-34 135.0 COG0318@1|root,COG0318@2|Bacteria,4PN9Z@976|Bacteroidetes 976|Bacteroidetes IQ AMP-dependent synthetase and ligase - - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding CMS3_k127_630266_1 688270.Celal_1441 1.405e-15 83.0 COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia 976|Bacteroidetes M PFAM MORN repeat variant - - - - - - - - - - - - MORN_2,TPR_1,TPR_16,TPR_8 CMS3_k127_630266_0 595460.RRSWK_06791 1.284e-180 584.0 COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes 203682|Planctomycetes CP COG3119 Arylsulfatase A - - - ko:K01138 - - - - ko00000,ko01000 - - - HEAT_2,Sulfatase CMS3_k127_6307021_3 1313301.AUGC01000009_gene1034 2.6e-60 214.0 COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes 976|Bacteroidetes F uridine kinase udk - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK CMS3_k127_6307021_2 1237149.C900_02441 1.857e-69 246.0 COG0463@1|root,COG0463@2|Bacteria,4PPKA@976|Bacteroidetes,47YP2@768503|Cytophagia 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_6307021_1 1499686.BN1079_01550 2.256e-92 317.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_6307021_0 1313301.AUGC01000006_gene138 2.553e-128 419.0 COG1186@1|root,COG1186@2|Bacteria,4NEN1@976|Bacteroidetes 976|Bacteroidetes J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 CMS3_k127_6307021_5 518766.Rmar_1447 5.76e-25 109.0 COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1FJG7@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes L Uncharacterised protein family UPF0102 - - - ko:K07460 - - - - ko00000 - - - UPF0102 CMS3_k127_6307021_7 1279009.ADICEAN_00509 4.437e-07 60.0 2E2E1@1|root,32XIR@2|Bacteria,4NUDT@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6307021_4 1122176.KB903542_gene389 1.641e-53 192.0 COG1437@1|root,COG1437@2|Bacteria,4NQQK@976|Bacteroidetes 976|Bacteroidetes F CYTH domain - - - - - - - - - - - - CYTH CMS3_k127_6317817_0 762903.Pedsa_2820 3.703e-120 394.0 COG0449@1|root,COG0449@2|Bacteria,4NE8Q@976|Bacteroidetes,1IPQZ@117747|Sphingobacteriia 976|Bacteroidetes M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS CMS3_k127_6317817_2 1185876.BN8_04630 7.944e-23 113.0 28J4T@1|root,2Z90P@2|Bacteria,4NHUC@976|Bacteroidetes,47RDH@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4270) - - - - - - - - - - - - DUF4270 CMS3_k127_6317817_1 1124780.ANNU01000052_gene3562 2.225e-96 323.0 COG0297@1|root,COG0297@2|Bacteria,4NFP8@976|Bacteroidetes,47KUD@768503|Cytophagia 976|Bacteroidetes G PFAM Starch synthase catalytic domain glgA - 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5 CMS3_k127_6327151_1 195250.CM001776_gene4005 1.538e-44 168.0 COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria 1117|Cyanobacteria S tetratricopeptide - - - - - - - - - - - - TPR_16,TPR_8 CMS3_k127_6327151_4 1408813.AYMG01000029_gene4700 4.35e-10 66.0 COG3391@1|root,COG4447@1|root,COG5184@1|root,COG3391@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,4NPFW@976|Bacteroidetes,1IPJI@117747|Sphingobacteriia 976|Bacteroidetes DZ PFAM IPT TIG domain - - - - - - - - - - - - DUF5013,TIG CMS3_k127_6327151_0 1279009.ADICEAN_00500 4.368e-73 258.0 COG1752@1|root,COG1752@2|Bacteria 2|Bacteria M Esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin CMS3_k127_6327151_2 760192.Halhy_2348 8.954e-31 128.0 2BT60@1|root,32NAZ@2|Bacteria,4P6EN@976|Bacteroidetes,1IZF8@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6327151_3 1454007.JAUG01000124_gene1073 5.02e-29 120.0 COG0681@1|root,COG0681@2|Bacteria,4NFTP@976|Bacteroidetes,1IRAK@117747|Sphingobacteriia 976|Bacteroidetes U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 CMS3_k127_63340_2 700598.Niako_4059 5.699e-13 80.0 28Q1T@1|root,2ZCK1@2|Bacteria,4NN1T@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_63340_1 251221.35213616 9.851e-49 179.0 COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria 1117|Cyanobacteria S MOSC domain - - - - - - - - - - - - - CMS3_k127_63340_0 1449976.KALB_3136 2.094e-178 575.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,2GKBW@201174|Actinobacteria,4E0GX@85010|Pseudonocardiales 201174|Actinobacteria C Pyruvate ferredoxin/flavodoxin oxidoreductase - - 1.2.7.8 ko:K00179,ko:K04090 - - - - br01601,ko00000,ko01000 - - - Fer4,POR,POR_N,TPP_enzyme_C CMS3_k127_6360793_4 382464.ABSI01000013_gene1727 9.613e-05 48.0 COG1388@1|root,COG1388@2|Bacteria,46T61@74201|Verrucomicrobia 74201|Verrucomicrobia M N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2,LysM CMS3_k127_6360793_3 1124780.ANNU01000044_gene486 1.836e-20 102.0 2BSR1@1|root,32MTV@2|Bacteria,4NS3P@976|Bacteroidetes,47QP7@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6360793_0 1288963.ADIS_3068 1.384e-150 500.0 COG3458@1|root,COG3458@2|Bacteria,4NJMX@976|Bacteroidetes,47TKJ@768503|Cytophagia 976|Bacteroidetes Q Acetyl xylan esterase (AXE1) - - - - - - - - - - - - AXE1 CMS3_k127_6360793_2 504472.Slin_1939 6.738e-23 104.0 29TMV@1|root,30EVG@2|Bacteria,4NNPM@976|Bacteroidetes,47RB5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6360793_1 313606.M23134_02255 1.422e-132 441.0 COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,47XXA@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6378863_7 1121904.ARBP01000006_gene3817 8.763e-20 90.0 COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,47K7Z@768503|Cytophagia 976|Bacteroidetes G PFAM Xylose isomerase-like TIM barrel - - 5.3.1.22 ko:K01816 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 CMS3_k127_6378863_4 760192.Halhy_6135 2.73e-85 294.0 COG1477@1|root,COG1477@2|Bacteria,4NGEK@976|Bacteroidetes,1IXYF@117747|Sphingobacteriia 976|Bacteroidetes H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE CMS3_k127_6378863_0 1121904.ARBP01000018_gene2626 1.017e-195 619.0 COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,47JCP@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,TAT_signal CMS3_k127_6378863_1 1121904.ARBP01000018_gene2627 6.534e-142 457.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,47MAP@768503|Cytophagia 976|Bacteroidetes C PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - Cytochrom_NNT,FGE-sulfatase CMS3_k127_6378863_6 1121904.ARBP01000018_gene2628 4.18e-23 106.0 COG2353@1|root,COG2353@2|Bacteria 2|Bacteria O YceI-like domain - - - - - - - - - - - - YceI CMS3_k127_6378863_3 1121904.ARBP01000002_gene7183 9.491e-91 304.0 COG3291@1|root,COG3291@2|Bacteria,4PMYH@976|Bacteroidetes,47YKQ@768503|Cytophagia 976|Bacteroidetes S Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_6378863_5 1237149.C900_00402 1.155e-71 252.0 COG0596@1|root,COG0596@2|Bacteria,4PNPN@976|Bacteroidetes,47XAU@768503|Cytophagia 976|Bacteroidetes S Ndr family - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 CMS3_k127_6378863_2 489825.LYNGBM3L_06000 8.187e-132 433.0 COG3497@1|root,COG3497@2|Bacteria,1GBY4@1117|Cyanobacteria,1HEZY@1150|Oscillatoriales 1117|Cyanobacteria S Phage tail sheath C-terminal domain - - - - - - - - - - - - Phage_sheath_1,Phage_sheath_1C CMS3_k127_6384844_2 761193.Runsl_1134 9.567e-145 466.0 COG5434@1|root,COG5434@2|Bacteria,4NFZJ@976|Bacteroidetes,47K9P@768503|Cytophagia 976|Bacteroidetes M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - PSCyt1,fn3 CMS3_k127_6384844_0 1121904.ARBP01000010_gene2244 1.799e-204 646.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47M3C@768503|Cytophagia 976|Bacteroidetes P PFAM sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_6384844_1 551789.ATVJ01000002_gene2689 9.701e-173 555.0 COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VF3C@28211|Alphaproteobacteria,43WX5@69657|Hyphomonadaceae 28211|Alphaproteobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF CMS3_k127_6384844_6 1122137.AQXF01000007_gene3584 0.0003034 50.0 2CGK2@1|root,2ZSMN@2|Bacteria,1PB67@1224|Proteobacteria,2UWR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_6384844_4 365044.Pnap_2179 2.827e-79 271.0 COG3212@1|root,COG3212@2|Bacteria,1N0D3@1224|Proteobacteria 1224|Proteobacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - PepSY CMS3_k127_6384844_3 700598.Niako_6465 1.969e-112 379.0 COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1ISPB@117747|Sphingobacteriia 976|Bacteroidetes V COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - - - - - - - - - - Beta-lactamase CMS3_k127_6384844_5 1121875.KB907547_gene3398 4.162e-22 96.0 COG2346@1|root,COG2346@2|Bacteria,4NQCV@976|Bacteroidetes,1IJ52@117743|Flavobacteriia 976|Bacteroidetes S Bacterial-like globin - - - ko:K06886 - - - - ko00000 - - - Bac_globin CMS3_k127_638878_3 1288963.ADIS_2044 2.652e-06 56.0 COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47PCS@768503|Cytophagia 976|Bacteroidetes S MORN repeat variant - - - - - - - - - - - - MORN_2 CMS3_k127_638878_1 700598.Niako_6704 1.121e-134 433.0 COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1IPCE@117747|Sphingobacteriia 976|Bacteroidetes Q PFAM Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase CMS3_k127_638878_2 1123057.P872_12500 2.269e-90 305.0 COG1028@1|root,COG1028@2|Bacteria,4NH6R@976|Bacteroidetes,47KYG@768503|Cytophagia 976|Bacteroidetes IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059,ko:K18333 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671 RC00029,RC00066,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_638878_0 926562.Oweho_0067 8.941e-150 494.0 28HH2@1|root,2Z7ST@2|Bacteria,4NMWR@976|Bacteroidetes,1I1Q4@117743|Flavobacteriia 976|Bacteroidetes M Thiol-activated cytolysin - - - ko:K11031 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - Thiol_cytolysin CMS3_k127_6398657_1 1453498.LG45_07550 1.157e-43 171.0 COG1835@1|root,COG1835@2|Bacteria,4NIR9@976|Bacteroidetes,1HXXY@117743|Flavobacteriia,2NU3D@237|Flavobacterium 976|Bacteroidetes I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 CMS3_k127_6398657_2 760192.Halhy_3918 2.756e-43 164.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,1IW4Z@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6398657_0 1122179.KB890425_gene3461 4.693e-139 456.0 COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,4NDU2@976|Bacteroidetes,1IX7D@117747|Sphingobacteriia 976|Bacteroidetes ET Amino acid permease - - - - - - - - - - - - AA_permease,AA_permease_2,PTS_EIIA_2,TrkA_C CMS3_k127_6402236_3 1392490.JHZX01000001_gene1920 9.021e-07 60.0 COG3291@1|root,COG4935@1|root,COG3291@2|Bacteria,COG4935@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - CHU_C,CUB,Cleaved_Adhesin,MAM,PKD,fn3 CMS3_k127_6402236_2 886882.PPSC2_c4512 3.967e-12 73.0 2CKD9@1|root,333BQ@2|Bacteria,1VIGZ@1239|Firmicutes,4HQNF@91061|Bacilli,26RC6@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - CMS3_k127_6402236_0 886379.AEWI01000023_gene38 3.216e-210 663.0 COG0119@1|root,COG0119@2|Bacteria,4NEIT@976|Bacteroidetes,2FNX8@200643|Bacteroidia,3XIXN@558415|Marinilabiliaceae 976|Bacteroidetes E LeuA allosteric (dimerisation) domain leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer CMS3_k127_6402236_1 643867.Ftrac_1644 2.033e-44 162.0 COG0065@1|root,COG0065@2|Bacteria,4NG7E@976|Bacteroidetes,47JAE@768503|Cytophagia 976|Bacteroidetes E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase CMS3_k127_6407223_3 344747.PM8797T_12933 2.359e-69 241.0 COG2133@1|root,COG2133@2|Bacteria,2IWVG@203682|Planctomycetes 203682|Planctomycetes G pyrroloquinoline quinone binding - - - - - - - - - - - - - CMS3_k127_6407223_1 1168034.FH5T_14590 2.735e-75 260.0 COG2755@1|root,COG2755@2|Bacteria,4NMUB@976|Bacteroidetes,2FQW2@200643|Bacteroidia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 CMS3_k127_6407223_0 1286632.P278_29940 9.895e-230 720.0 COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,1HYF8@117743|Flavobacteriia 976|Bacteroidetes P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - DUF4994,Sulfatase CMS3_k127_6407223_4 391625.PPSIR1_02216 4.02e-35 139.0 COG1611@1|root,COG1611@2|Bacteria,1RJ91@1224|Proteobacteria,42TR7@68525|delta/epsilon subdivisions,2WQUE@28221|Deltaproteobacteria,2Z1AI@29|Myxococcales 28221|Deltaproteobacteria S PFAM conserved - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - DNA_processg_A,Lysine_decarbox CMS3_k127_6407223_2 566466.NOR53_2211 1.279e-73 250.0 COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,1RY1C@1236|Gammaproteobacteria,1J7RH@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_6407773_2 641524.ADICYQ_5798 3.476e-66 232.0 COG2610@1|root,COG2610@2|Bacteria,4NJ5B@976|Bacteroidetes,47K2S@768503|Cytophagia 976|Bacteroidetes EG PFAM Gluconate transporter - - - - - - - - - - - - GntP_permease CMS3_k127_6407773_0 518766.Rmar_1741 5.227e-142 467.0 COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_6407773_1 880070.Cycma_1834 5.532e-133 430.0 COG1082@1|root,COG1082@2|Bacteria,4NG1K@976|Bacteroidetes,47JT7@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_6407773_3 1519464.HY22_10085 1.557e-56 205.0 COG4636@1|root,COG4636@2|Bacteria 2|Bacteria D protein conserved in cyanobacteria - - - - - - - - - - - - Uma2 CMS3_k127_6409482_1 1123248.KB893348_gene194 1.507e-103 363.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NJMF@976|Bacteroidetes,1IWR7@117747|Sphingobacteriia 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - His_kinase,Reg_prop,Y_Y_Y CMS3_k127_6409482_3 1122176.KB903561_gene3586 5.226e-50 183.0 COG2353@1|root,COG2353@2|Bacteria,4NI82@976|Bacteroidetes,1IXPV@117747|Sphingobacteriia 976|Bacteroidetes S YceI-like domain - - - - - - - - - - - - YceI CMS3_k127_6409482_4 485917.Phep_0333 2.51e-15 80.0 2C8H5@1|root,336VW@2|Bacteria,4NVF0@976|Bacteroidetes,1IZU4@117747|Sphingobacteriia 976|Bacteroidetes C Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - - - - - - - - - - HIPIP CMS3_k127_6409482_0 1288963.ADIS_1496 1.817e-188 610.0 COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,4NGAU@976|Bacteroidetes,47NUR@768503|Cytophagia 976|Bacteroidetes C SPTR Membrane-bound dehydrogenase domain protein - - - - - - - - - - - - Cytochrom_C CMS3_k127_6409482_2 1288963.ADIS_3297 8.098e-90 305.0 COG3356@1|root,COG3356@2|Bacteria,4NJPV@976|Bacteroidetes,47JM2@768503|Cytophagia 976|Bacteroidetes S Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - - - - - - - - - - Ceramidase_alk CMS3_k127_642738_3 1121904.ARBP01000004_gene1108 4.66e-48 183.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_642738_1 643867.Ftrac_3430 8.503e-87 294.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_642738_6 1095769.CAHF01000011_gene2292 1.724e-09 68.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - - - - - - - - - - - Lipase_GDSL_2,Polysacc_deac_1 CMS3_k127_642738_2 236814.IX39_01860 1.709e-72 248.0 COG2110@1|root,COG2110@2|Bacteria,4NNRH@976|Bacteroidetes,1I2GR@117743|Flavobacteriia,3ZPRW@59732|Chryseobacterium 976|Bacteroidetes S O-acetyl-ADP-ribose deacetylase 1 - - - - - - - - - - - - Macro CMS3_k127_642738_5 388413.ALPR1_15929 1.671e-26 119.0 2DP33@1|root,330AX@2|Bacteria,4NX23@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_642738_0 1313421.JHBV01000024_gene5028 6.133e-106 350.0 COG4295@1|root,COG4295@2|Bacteria,4NMXI@976|Bacteroidetes,1IXC8@117747|Sphingobacteriia 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2263) - - - - - - - - - - - - DUF2263 CMS3_k127_642738_4 204669.Acid345_1382 7.474e-46 171.0 2BM3X@1|root,33KY1@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_6442121_1 706436.HMPREF9074_08050 2.662e-16 86.0 2DR35@1|root,339YY@2|Bacteria,4NWVB@976|Bacteroidetes,1I5UJ@117743|Flavobacteriia,1EQZG@1016|Capnocytophaga 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6442121_0 929556.Solca_4486 5.545e-71 250.0 COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IR3W@117747|Sphingobacteriia 976|Bacteroidetes V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6443917_0 1121904.ARBP01000006_gene3864 1.443e-67 241.0 COG1360@1|root,COG1360@2|Bacteria,4NN97@976|Bacteroidetes,47QKF@768503|Cytophagia 976|Bacteroidetes N Flagellar Motor Protein - - - - - - - - - - - - OmpA CMS3_k127_6443917_1 1189619.pgond44_13417 2.258e-14 86.0 COG3307@1|root,COG3307@2|Bacteria,4PD9V@976|Bacteroidetes,1IDSZ@117743|Flavobacteriia,4C4GP@83612|Psychroflexus 976|Bacteroidetes M O-antigen ligase like membrane protein - - - - - - - - - - - - - CMS3_k127_6443917_2 649831.L083_7358 2.9e-06 58.0 COG1520@1|root,COG3291@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4DMTQ@85008|Micromonosporales 201174|Actinobacteria S Laminin G domain - - - - - - - - - - - - DUF5122,Laminin_G_3 CMS3_k127_6455623_1 1296416.JACB01000032_gene2291 1.648e-40 155.0 COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,1I0QN@117743|Flavobacteriia,2YJJY@290174|Aquimarina 976|Bacteroidetes T LytTr DNA-binding domain - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_6455623_3 935836.JAEL01000085_gene4646 3.77e-21 101.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HI6P@91061|Bacilli,1ZPVW@1386|Bacillus 91061|Bacilli CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c resA - - - - - - - - - - - AhpC-TSA CMS3_k127_6455623_4 682795.AciX8_3916 4.214e-10 66.0 COG4232@1|root,COG4232@2|Bacteria,3Y5QG@57723|Acidobacteria,2JK1Z@204432|Acidobacteriia 204432|Acidobacteriia CO Disulphide bond corrector protein DsbC - - - - - - - - - - - - DsbC CMS3_k127_6455623_2 926559.JoomaDRAFT_3943 4.421e-32 131.0 COG1396@1|root,COG1396@2|Bacteria,4NR5F@976|Bacteroidetes,1I34G@117743|Flavobacteriia 976|Bacteroidetes K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 CMS3_k127_6455623_0 1250232.JQNJ01000001_gene3429 4.937e-98 331.0 COG0457@1|root,COG0457@2|Bacteria,4NIKS@976|Bacteroidetes,1I09K@117743|Flavobacteriia 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - TPR_12,TPR_8 CMS3_k127_6456231_10 1121931.AUHG01000011_gene2169 1.35e-60 216.0 COG1028@1|root,COG1028@2|Bacteria,4NGAH@976|Bacteroidetes,1HZ3Z@117743|Flavobacteriia 976|Bacteroidetes IQ with different specificities (Related to short-chain alcohol - - - - - - - - - - - - adh_short_C2 CMS3_k127_6456231_3 760192.Halhy_4520 6.649e-196 622.0 COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,1IRNW@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_6456231_9 985255.APHJ01000054_gene1991 6.437e-63 226.0 COG0697@1|root,COG0697@2|Bacteria,4PCHD@976|Bacteroidetes,1ID38@117743|Flavobacteriia,2P7BY@244698|Gillisia 976|Bacteroidetes EG EamA-like transporter family - - - - - - - - - - - - EamA CMS3_k127_6456231_14 1121104.AQXH01000001_gene1965 1.101e-09 65.0 COG1524@1|root,COG1524@2|Bacteria,4NFFG@976|Bacteroidetes,1IWYJ@117747|Sphingobacteriia 976|Bacteroidetes S Type I phosphodiesterase / nucleotide pyrophosphatase - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phosphodiest CMS3_k127_6456231_1 1122176.KB903576_gene4886 1.609e-241 751.0 COG1228@1|root,COG1228@2|Bacteria,4NISN@976|Bacteroidetes,1J19G@117747|Sphingobacteriia 976|Bacteroidetes Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 CMS3_k127_6456231_5 240016.ABIZ01000001_gene1332 4.311e-168 551.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - Sulfatase CMS3_k127_6456231_11 500637.PROVRUST_07676 3.595e-55 217.0 2DMN1@1|root,32SKS@2|Bacteria,1RCAE@1224|Proteobacteria,1S2KJ@1236|Gammaproteobacteria,3Z7XB@586|Providencia 1236|Gammaproteobacteria S Carbohydrate family 9 binding domain-like VY92_09500 - - - - - - - - - - - CBM9_1 CMS3_k127_6456231_2 1379270.AUXF01000005_gene764 5.608e-196 633.0 COG2366@1|root,COG2366@2|Bacteria,1ZUMU@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Penicillin amidase - - 3.5.1.97 ko:K07116 - - - - ko00000,ko01000 - - - Penicil_amidase CMS3_k127_6456231_12 1123057.P872_16695 4.518e-48 175.0 2BWYK@1|root,32R5D@2|Bacteria,4NS4D@976|Bacteroidetes,47UWC@768503|Cytophagia 976|Bacteroidetes T PAS domain - - - - - - - - - - - - PAS_4,PAS_8 CMS3_k127_6456231_7 1305737.JAFX01000001_gene1972 1.361e-94 319.0 COG1235@1|root,COG1235@2|Bacteria,4NM16@976|Bacteroidetes,47U32@768503|Cytophagia 976|Bacteroidetes S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 CMS3_k127_6456231_0 398720.MED217_11914 4.948e-314 977.0 COG2234@1|root,COG2234@2|Bacteria,4NI5W@976|Bacteroidetes,1HXHX@117743|Flavobacteriia,2XK11@283735|Leeuwenhoekiella 976|Bacteroidetes S Transferrin receptor-like dimerisation domain - - 3.4.17.21 ko:K01301 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28,TFR_dimer CMS3_k127_6456231_6 344747.PM8797T_04345 1.005e-145 469.0 COG1446@1|root,COG1446@2|Bacteria,2IZ4V@203682|Planctomycetes 203682|Planctomycetes E PFAM peptidase T2 asparaginase 2 - - 3.4.19.5,3.5.1.26 ko:K01444,ko:K13051 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000,ko01002 - - - Asparaginase_2,DUF4440 CMS3_k127_6456231_13 760192.Halhy_6223 3.528e-34 145.0 28I8D@1|root,2Z8B7@2|Bacteria,4NM23@976|Bacteroidetes,1ISNF@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_6456231_4 760192.Halhy_6222 4.547e-176 580.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IPMB@117747|Sphingobacteriia 976|Bacteroidetes P TonB-dependent receptor plug domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6456231_8 1123242.JH636434_gene4153 2.633e-85 289.0 COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes 203682|Planctomycetes G BNR repeat-like domain - - - - - - - - - - - - BNR_2 CMS3_k127_6461929_1 1185876.BN8_03986 4.783e-50 182.0 COG2318@1|root,COG2318@2|Bacteria,4NQBY@976|Bacteroidetes,47PR7@768503|Cytophagia 976|Bacteroidetes S DinB superfamily - - - - - - - - - - - - DinB_2 CMS3_k127_6461929_0 1122176.KB903536_gene1827 1.553e-125 428.0 COG0464@1|root,COG0464@2|Bacteria,4P0AA@976|Bacteroidetes 976|Bacteroidetes O growth - - - - - - - - - - - - - CMS3_k127_6462114_5 1121456.ATVA01000012_gene2676 1.247e-05 53.0 COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2M7W6@213115|Desulfovibrionales 28221|Deltaproteobacteria M Belongs to the ompA family - - - ko:K03286 - - - - ko00000,ko02000 1.B.6 - - OmpA,TSP_3,VWA,VWA_2 CMS3_k127_6462114_4 984262.SGRA_2472 1.13e-22 104.0 2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1IUKR@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6462114_1 926549.KI421517_gene1358 7.016e-67 232.0 COG1595@1|root,COG1595@2|Bacteria,4NMC0@976|Bacteroidetes,47N5B@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6462114_0 700598.Niako_5074 1.198e-179 571.0 COG0415@1|root,COG0415@2|Bacteria,4NEDW@976|Bacteroidetes,1IQZJ@117747|Sphingobacteriia 976|Bacteroidetes L DNA photolyase phr - 4.1.99.3 ko:K01669 - - - - ko00000,ko01000,ko03400 - - - DNA_photolyase,FAD_binding_7 CMS3_k127_6462114_3 641107.CDLVIII_1054 2.166e-24 104.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,248SF@186801|Clostridia,36GXS@31979|Clostridiaceae 186801|Clostridia G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A CMS3_k127_6467920_0 1123277.KB893180_gene2461 2.533e-160 513.0 COG3525@1|root,COG3525@2|Bacteria,4NGV2@976|Bacteroidetes,47TJT@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 20, catalytic domain - - - - - - - - - - - - Glyco_hydro_20 CMS3_k127_6479991_4 1237149.C900_02937 2.918e-58 213.0 COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS3_k127_6479991_5 1237149.C900_02938 4.292e-31 135.0 COG2374@1|root,COG2374@2|Bacteria 2|Bacteria - - - - - ko:K07004 - - - - ko00000 - - - Big_4,Big_5,DUF3494,LTD,SLH CMS3_k127_6479991_3 385682.AFSL01000064_gene1720 6.538e-59 211.0 COG0811@1|root,COG0811@2|Bacteria,4NFIX@976|Bacteroidetes,2FNG0@200643|Bacteroidia,3XIUJ@558415|Marinilabiliaceae 976|Bacteroidetes U MotA/TolQ/ExbB proton channel family exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB CMS3_k127_6479991_9 1341155.FSS13T_23870 1.62e-06 55.0 COG0848@1|root,COG0848@2|Bacteria,4NNI6@976|Bacteroidetes,1I25E@117743|Flavobacteriia,2P07I@237|Flavobacterium 976|Bacteroidetes U Biopolymer transport protein ExbD/TolR exbD - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD CMS3_k127_6479991_1 1122179.KB890442_gene1152 7.942e-95 325.0 COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes 976|Bacteroidetes M COG5337 Spore coat assembly protein - - - - - - - - - - - - CotH,LTD CMS3_k127_6479991_8 1046627.BZARG_3041 1.654e-09 69.0 2DGGX@1|root,2ZVY4@2|Bacteria,4NQ0P@976|Bacteroidetes,1I6WK@117743|Flavobacteriia 976|Bacteroidetes S YARHG - - - - - - - - - - - - YARHG CMS3_k127_6479991_6 1380384.JADN01000004_gene1736 2.794e-21 105.0 COG0791@1|root,COG0791@2|Bacteria,4NSZJ@976|Bacteroidetes,1I2VP@117743|Flavobacteriia 976|Bacteroidetes M NlpC P60 family nlpC - - ko:K13695 - - - - ko00000,ko01002 - - - LysM,NLPC_P60 CMS3_k127_6479991_0 1237149.C900_05681 6.964e-130 428.0 COG2367@1|root,COG2866@1|root,COG2367@2|Bacteria,COG2866@2|Bacteria,4NH6K@976|Bacteroidetes,47K31@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 CMS3_k127_6479991_2 926549.KI421517_gene3889 1.195e-78 270.0 COG2884@1|root,COG2884@2|Bacteria,4NEP2@976|Bacteroidetes,47MP4@768503|Cytophagia 976|Bacteroidetes D PFAM ABC transporter ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran CMS3_k127_6479991_7 929556.Solca_0913 9.285e-11 64.0 2E6NQ@1|root,33195@2|Bacteria,4NV7Z@976|Bacteroidetes,1IU05@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6492996_0 1434325.AZQN01000001_gene187 7.412e-98 330.0 COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47T8D@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_6492996_2 1434325.AZQN01000003_gene2401 9.582e-28 115.0 2C85M@1|root,334CZ@2|Bacteria,4NSRZ@976|Bacteroidetes,47SET@768503|Cytophagia 976|Bacteroidetes S Stress responsive A/B Barrel Domain - - - - - - - - - - - - Dabb CMS3_k127_6492996_1 1267211.KI669560_gene2807 4.852e-29 119.0 COG1846@1|root,COG1846@2|Bacteria,4PKFS@976|Bacteroidetes,1IZ1N@117747|Sphingobacteriia 976|Bacteroidetes K Winged helix DNA-binding domain marR - - - - - - - - - - - HTH_34 CMS3_k127_6492996_3 700598.Niako_6912 3.872e-23 106.0 295IV@1|root,2ZSWC@2|Bacteria,4NVMA@976|Bacteroidetes,1IZ1W@117747|Sphingobacteriia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - CMS3_k127_649404_2 1408473.JHXO01000006_gene1405 3.898e-13 74.0 COG1555@1|root,COG1555@2|Bacteria,4NK4K@976|Bacteroidetes,2FPCH@200643|Bacteroidia 976|Bacteroidetes L Psort location Cytoplasmic, score 8.96 comEA - - - - - - - - - - - HHH_3 CMS3_k127_649404_1 485917.Phep_0836 9.913e-47 175.0 COG0503@1|root,COG0503@2|Bacteria,4NP7K@976|Bacteroidetes,1IS3F@117747|Sphingobacteriia 976|Bacteroidetes F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran CMS3_k127_649404_0 153721.MYP_4817 1.126e-174 555.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47K4J@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_6499987_2 945713.IALB_2784 2.615e-84 293.0 COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides cpt - 3.4.17.18 ko:K05996 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M14,Peptidase_M6 CMS3_k127_6499987_0 313606.M23134_00640 3.817e-262 847.0 COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,47KIF@768503|Cytophagia 976|Bacteroidetes S Peptidase family C25 porU - - - - - - - - - - - Peptidase_C25 CMS3_k127_6499987_1 509635.N824_12965 1.182e-107 361.0 COG2067@1|root,COG2067@2|Bacteria,4NDZW@976|Bacteroidetes,1IPX7@117747|Sphingobacteriia 976|Bacteroidetes I long-chain fatty acid transport protein porV - - - - - - - - - - - - CMS3_k127_6499987_3 1131812.JQMS01000001_gene3052 2.274e-73 255.0 COG0169@1|root,COG0169@2|Bacteria,4NEBJ@976|Bacteroidetes,1HX5T@117743|Flavobacteriia,2NTHH@237|Flavobacterium 976|Bacteroidetes E catalyzes the conversion of shikimate to 3-dehydroshikimate aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N CMS3_k127_6500361_19 1121007.AUML01000002_gene1624 0.0006591 45.0 COG2885@1|root,COG2885@2|Bacteria,4NQ8U@976|Bacteroidetes,1I3UW@117743|Flavobacteriia,2YIWW@290174|Aquimarina 976|Bacteroidetes M OmpA family - - - - - - - - - - - - OmpA CMS3_k127_6500361_5 234267.Acid_5529 1.243e-141 459.0 COG1312@1|root,COG1312@2|Bacteria,3Y693@57723|Acidobacteria 57723|Acidobacteria G D-mannonate dehydratase (UxuA) - - 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - UxuA CMS3_k127_6500361_10 1408473.JHXO01000004_gene112 3.63e-70 247.0 COG3264@1|root,COG3264@2|Bacteria,4NEAM@976|Bacteroidetes,2FSYM@200643|Bacteroidia 976|Bacteroidetes M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel CMS3_k127_6500361_1 525373.HMPREF0766_10277 1.642e-239 779.0 COG1629@1|root,COG4771@2|Bacteria,4P0X2@976|Bacteroidetes,1IVJ0@117747|Sphingobacteriia 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6500361_9 525373.HMPREF0766_10278 6.243e-74 269.0 COG4198@1|root,COG4198@2|Bacteria,4P1AT@976|Bacteroidetes,1IUW6@117747|Sphingobacteriia 976|Bacteroidetes S Starch-binding associating with outer membrane - - - - - - - - - - - - SusD-like_2 CMS3_k127_6500361_3 313603.FB2170_14288 8.736e-166 534.0 COG3419@1|root,COG3419@2|Bacteria,4NGV9@976|Bacteroidetes 976|Bacteroidetes NU Tfp pilus assembly protein tip-associated adhesin - - - - - - - - - - - - PQQ,PQQ_2 CMS3_k127_6500361_0 1121011.AUCB01000013_gene171 0.0 1290.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,1HX4C@117743|Flavobacteriia,23HTQ@178469|Arenibacter 976|Bacteroidetes S FG-GAP repeat - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_6500361_7 926549.KI421517_gene4029 3.466e-139 472.0 COG1629@1|root,COG1629@2|Bacteria,4PM9F@976|Bacteroidetes,47YJ8@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarboxypepD_reg,Plug CMS3_k127_6500361_18 28377.ENSACAP00000016079 0.0002215 51.0 KOG1218@1|root,KOG1218@2759|Eukaryota,38CGW@33154|Opisthokonta,3BEXX@33208|Metazoa,3CV8Y@33213|Bilateria,47Z98@7711|Chordata,4987A@7742|Vertebrata 33208|Metazoa T Stabilin 2 STAB2 GO:0001525,GO:0001568,GO:0001944,GO:0003674,GO:0003824,GO:0005041,GO:0005044,GO:0005488,GO:0005539,GO:0005540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0006950,GO:0006952,GO:0007155,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009897,GO:0009986,GO:0009987,GO:0012506,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016054,GO:0016192,GO:0016491,GO:0016667,GO:0019752,GO:0022610,GO:0030139,GO:0030169,GO:0030203,GO:0030212,GO:0030214,GO:0030228,GO:0030659,GO:0030666,GO:0031090,GO:0031224,GO:0031226,GO:0031406,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0035239,GO:0035295,GO:0036094,GO:0038024,GO:0042742,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0046395,GO:0048514,GO:0048646,GO:0048731,GO:0048856,GO:0050830,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055114,GO:0071704,GO:0071813,GO:0071814,GO:0071944,GO:0072358,GO:0072359,GO:0097367,GO:0097708,GO:0098542,GO:0098552,GO:0098588,GO:0098657,GO:0098805,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903510 - ko:K19013,ko:K19020 - - - - ko00000,ko00536 - - - EGF_3,Fasciclin,Xlink CMS3_k127_6500361_17 51337.XP_004660076.1 4.74e-08 62.0 COG2335@1|root,KOG1437@2759|Eukaryota,39MP0@33154|Opisthokonta,3BB62@33208|Metazoa,3D1UP@33213|Bilateria,4818S@7711|Chordata,492WH@7742|Vertebrata,3J8XE@40674|Mammalia,35DGV@314146|Euarchontoglires,4PVCT@9989|Rodentia 33208|Metazoa MW Periostin POSTN GO:0000902,GO:0001501,GO:0001817,GO:0001819,GO:0001952,GO:0001953,GO:0002791,GO:0002793,GO:0003008,GO:0003013,GO:0003073,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0007154,GO:0007155,GO:0007162,GO:0007275,GO:0007399,GO:0007584,GO:0008015,GO:0008150,GO:0008201,GO:0008217,GO:0008593,GO:0009605,GO:0009653,GO:0009888,GO:0009966,GO:0009987,GO:0009991,GO:0010646,GO:0010721,GO:0010769,GO:0010771,GO:0010810,GO:0010812,GO:0012505,GO:0014910,GO:0014911,GO:0016043,GO:0016049,GO:0022008,GO:0022603,GO:0022604,GO:0022610,GO:0023051,GO:0030030,GO:0030154,GO:0030155,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0031012,GO:0031175,GO:0031594,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031984,GO:0032501,GO:0032502,GO:0032571,GO:0032642,GO:0032722,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0033273,GO:0040007,GO:0040012,GO:0040017,GO:0042221,GO:0043062,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045202,GO:0045595,GO:0045596,GO:0046872,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048588,GO:0048589,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051129,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051270,GO:0051272,GO:0051716,GO:0060284,GO:0060560,GO:0065007,GO:0065008,GO:0070201,GO:0070887,GO:0071295,GO:0071307,GO:0071496,GO:0071840,GO:0090087,GO:0090196,GO:0090197,GO:0097367,GO:0098791,GO:0120036,GO:0120039,GO:1900024,GO:1900025,GO:1901681,GO:1903530,GO:1903532,GO:1904207,GO:1904209,GO:1904951,GO:1990138,GO:2000145,GO:2000147,GO:2000341,GO:2000343 - ko:K19519 - - - - ko00000,ko04516 - - - Fasciclin CMS3_k127_6500361_12 761193.Runsl_1759 5.08e-48 181.0 COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,47PEW@768503|Cytophagia 976|Bacteroidetes E PFAM GDSL-like Lipase Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 CMS3_k127_6500361_8 331869.BAL199_12441 4.691e-90 307.0 COG1638@1|root,COG1638@2|Bacteria,1MXUZ@1224|Proteobacteria,2TTTA@28211|Alphaproteobacteria,4BRM0@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 MA20_17110 - - - - - - - - - - - DctP CMS3_k127_6500361_13 375451.RD1_3608 1.4e-42 161.0 COG3090@1|root,COG3090@2|Bacteria,1QXYB@1224|Proteobacteria,2TTWD@28211|Alphaproteobacteria,2P3YM@2433|Roseobacter 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS3_k127_6500361_2 331869.BAL199_12431 2.427e-168 540.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,4BRHR@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component MA20_17100 - - - - - - - - - - - DctM CMS3_k127_6500361_4 1121904.ARBP01000016_gene5281 1.889e-154 492.0 COG2084@1|root,COG2084@2|Bacteria,4NEF7@976|Bacteroidetes,47N6M@768503|Cytophagia 976|Bacteroidetes I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS3_k127_6500361_16 755732.Fluta_0541 3.335e-09 66.0 2DPTD@1|root,333AK@2|Bacteria,4NVNW@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6500361_11 1089547.KB913013_gene3990 1.455e-61 220.0 COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,47K8M@768503|Cytophagia 976|Bacteroidetes O Domain amino terminal to FKBP-type peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03772,ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N CMS3_k127_6500361_6 1250232.JQNJ01000001_gene115 2.07e-140 456.0 COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,1HXFV@117743|Flavobacteriia 976|Bacteroidetes G Glucose sorbosone gdhB - - ko:K21430 - - - - ko00000,ko01000 - - - GSDH CMS3_k127_6500361_14 1121011.AUCB01000009_gene1927 8.977e-37 143.0 COG2010@1|root,COG2010@2|Bacteria,4NEXP@976|Bacteroidetes,1HXBK@117743|Flavobacteriia,23IDH@178469|Arenibacter 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrom_C,Cytochrome_CBB3 CMS3_k127_6500361_15 1267211.KI669560_gene2123 2.382e-31 123.0 COG2234@1|root,COG2234@2|Bacteria,4NE66@976|Bacteroidetes,1INWN@117747|Sphingobacteriia 976|Bacteroidetes S Peptidase family M28 PGCP - - - - - - - - - - - Peptidase_M28 CMS3_k127_6509328_0 509635.N824_01200 8.297e-42 175.0 COG3386@1|root,COG5184@1|root,COG3386@2|Bacteria,COG5184@2|Bacteria,4NPFW@976|Bacteroidetes,1IPJI@117747|Sphingobacteriia 976|Bacteroidetes DZ PFAM IPT TIG domain - - - - - - - - - - - - DUF5013,TIG CMS3_k127_6509422_1 1122621.ATZA01000020_gene3999 2.315e-74 256.0 COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia 976|Bacteroidetes M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 CMS3_k127_6509422_2 1121098.HMPREF1534_00814 4.573e-62 222.0 COG1947@1|root,COG1947@2|Bacteria,4NGFC@976|Bacteroidetes,2FM2B@200643|Bacteroidia,4ANUK@815|Bacteroidaceae 976|Bacteroidetes F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CMS3_k127_6509422_0 886379.AEWI01000013_gene2197 2.984e-97 335.0 COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,2G2X9@200643|Bacteroidia,3XJH3@558415|Marinilabiliaceae 976|Bacteroidetes CO Domain of unknown function (DUF4369) - - - - - - - - - - - - AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8 CMS3_k127_6509422_3 1089547.KB913013_gene2566 1.099e-06 55.0 COG0526@1|root,COG0526@2|Bacteria,4NHEC@976|Bacteroidetes,47JHV@768503|Cytophagia 976|Bacteroidetes CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA,DUF4369,DUF5106,Thioredoxin_8 CMS3_k127_6509955_0 1121904.ARBP01000007_gene2889 9.719e-143 465.0 COG3127@1|root,COG3127@2|Bacteria,4NF16@976|Bacteroidetes,47MB7@768503|Cytophagia 976|Bacteroidetes Q FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6509955_1 1121904.ARBP01000007_gene2890 1.728e-102 337.0 COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia 976|Bacteroidetes Q ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_6509955_2 468059.AUHA01000002_gene726 1.253e-75 260.0 COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1IS4H@117747|Sphingobacteriia 976|Bacteroidetes E COG2755 Lysophospholipase L1 and related tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 CMS3_k127_6509955_3 745718.JADT01000009_gene3019 5.275e-66 237.0 2F6AM@1|root,33YUA@2|Bacteria,4P3YF@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - SH3_3 CMS3_k127_6509955_5 926562.Oweho_1915 5.855e-09 66.0 COG3291@1|root,COG3291@2|Bacteria,4P5U5@976|Bacteroidetes,1IAAB@117743|Flavobacteriia,2PB83@246874|Cryomorphaceae 976|Bacteroidetes S Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_6509955_4 997296.PB1_14684 1.597e-61 218.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 CMS3_k127_6511927_2 926549.KI421517_gene2688 1.243e-128 444.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NF1M@976|Bacteroidetes,47NC9@768503|Cytophagia 976|Bacteroidetes O Subtilase family - - 3.4.21.66 ko:K08651 - - - - ko00000,ko01000,ko01002,ko03110 - - - PKD,Peptidase_S8 CMS3_k127_6511927_3 391587.KAOT1_13367 2.932e-101 335.0 COG0740@1|root,COG0740@2|Bacteria,4NE20@976|Bacteroidetes,1HWT0@117743|Flavobacteriia 976|Bacteroidetes OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease CMS3_k127_6511927_1 385682.AFSL01000060_gene1758 5.646e-162 519.0 COG1219@1|root,COG1219@2|Bacteria,4NE1B@976|Bacteroidetes,2FMQV@200643|Bacteroidia,3XIWM@558415|Marinilabiliaceae 976|Bacteroidetes O ClpX C4-type zinc finger clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX CMS3_k127_6511927_0 760192.Halhy_5454 5.423e-197 620.0 COG4310@1|root,COG4310@2|Bacteria,4NH84@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF2172) - - - - - - - - - - - - DUF2172,DUF4910,HTH_47 CMS3_k127_6513950_0 251221.35212238 1.548e-174 565.0 COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria 1117|Cyanobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_6516067_0 313603.FB2170_07949 2.935e-189 595.0 COG0649@1|root,COG0649@2|Bacteria,4NF02@976|Bacteroidetes,1HZMG@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases CMS3_k127_6516067_2 1121875.KB907547_gene3142 4.522e-49 179.0 COG0852@1|root,COG0852@2|Bacteria,4NPZH@976|Bacteroidetes,1I1PJ@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa CMS3_k127_6516067_1 1121875.KB907547_gene3141 1.528e-85 288.0 COG0377@1|root,COG0377@2|Bacteria,4NFKT@976|Bacteroidetes,1I0R8@117743|Flavobacteriia 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 CMS3_k127_6517485_1 1189612.A33Q_0496 2.166e-24 104.0 COG4770@1|root,COG4770@2|Bacteria,4NQ86@976|Bacteroidetes,47QC5@768503|Cytophagia 976|Bacteroidetes I Acetyl propionyl-CoA carboxylase alpha subunit - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl CMS3_k127_6517485_2 926562.Oweho_2657 5.417e-14 76.0 COG3386@1|root,COG4386@1|root,COG3386@2|Bacteria,COG4386@2|Bacteria,4PP0K@976|Bacteroidetes,1IKDR@117743|Flavobacteriia,2PBMA@246874|Cryomorphaceae 976|Bacteroidetes G C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C CMS3_k127_6517485_0 886379.AEWI01000203_gene2533 4.505e-39 157.0 COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,2FKZG@200643|Bacteroidia,3XJX5@558415|Marinilabiliaceae 976|Bacteroidetes J RNA methyltransferase rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA CMS3_k127_6517894_0 1168034.FH5T_09710 9.217e-77 285.0 COG1287@1|root,COG1287@2|Bacteria,4NUWQ@976|Bacteroidetes 976|Bacteroidetes S oligosaccharyl transferase activity - - - - - - - - - - - - - CMS3_k127_6517894_2 504472.Slin_5990 0.0003135 53.0 COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,47N7J@768503|Cytophagia 976|Bacteroidetes O Subtilase family - - - - - - - - - - - - PKD,Peptidase_S8,fn3 CMS3_k127_6517894_1 56110.Oscil6304_2123 5.695e-25 120.0 COG2931@1|root,COG2931@2|Bacteria,1G4IS@1117|Cyanobacteria,1HAFZ@1150|Oscillatoriales 1117|Cyanobacteria Q RTX toxins and related Ca2 binding proteins - - - - - - - - - - - - Calx-beta,HemolysinCabind CMS3_k127_6530707_7 1273538.G159_13765 3.426e-06 52.0 COG1917@1|root,COG1917@2|Bacteria,1VKMG@1239|Firmicutes 1239|Firmicutes S Cupin domain - - - - - - - - - - - - Cupin_2 CMS3_k127_6530707_1 641524.ADICYQ_5434 5.265e-125 404.0 2DGT9@1|root,2ZX7M@2|Bacteria,4NNNP@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - DUF1961 CMS3_k127_6530707_3 1047013.AQSP01000120_gene970 7.72e-43 160.0 COG2367@1|root,COG2367@2|Bacteria,2NQ4B@2323|unclassified Bacteria 2|Bacteria V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2,Peptidase_S13 CMS3_k127_6530707_2 1123248.KB893315_gene2959 1.633e-60 211.0 COG4898@1|root,COG4898@2|Bacteria,4NQ4W@976|Bacteroidetes,1ISFJ@117747|Sphingobacteriia 976|Bacteroidetes S Uncharacterized protein conserved in bacteria (DUF2200) - - - - - - - - - - - - DUF2200 CMS3_k127_6530707_6 1123503.KB908056_gene1788 1.457e-23 102.0 COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2KFMY@204458|Caulobacterales 204458|Caulobacterales C aldo keto reductase - - - - - - - - - - - - Aldo_ket_red CMS3_k127_6530707_5 1121933.AUHH01000021_gene1645 2.777e-30 124.0 COG5485@1|root,COG5485@2|Bacteria,2IMH5@201174|Actinobacteria 201174|Actinobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL CMS3_k127_6530707_4 760192.Halhy_4294 1.83e-42 163.0 COG0666@1|root,COG0666@2|Bacteria,4P2SK@976|Bacteroidetes 976|Bacteroidetes S Ankyrin repeat - - - - - - - - - - - - - CMS3_k127_6530707_0 760192.Halhy_0549 2.601e-272 843.0 28JP4@1|root,2Z9F6@2|Bacteria,4NDYM@976|Bacteroidetes,1IVSV@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6551822_1 1124780.ANNU01000045_gene2299 6.035e-35 144.0 COG1501@1|root,COG1523@1|root,COG1501@2|Bacteria,COG1523@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31 CMS3_k127_6551822_0 760192.Halhy_6222 1.13e-79 286.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,1IPMB@117747|Sphingobacteriia 976|Bacteroidetes P TonB-dependent receptor plug domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6557711_1 1267533.KB906733_gene3362 3.313e-13 73.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia 204432|Acidobacteriia K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Trans_reg_C CMS3_k127_6557711_0 886379.AEWI01000052_gene2660 1.093e-132 434.0 COG1373@1|root,COG1373@2|Bacteria,4NE3E@976|Bacteroidetes,2FP33@200643|Bacteroidia 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 - - - ko:K07133 - - - - ko00000 - - - AAA_14 CMS3_k127_6557711_2 880071.Fleli_1322 6.347e-12 68.0 COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47XEN@768503|Cytophagia 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_6560184_2 1124780.ANNU01000008_gene2698 2.609e-69 237.0 COG1593@1|root,COG1593@2|Bacteria,4NE5T@976|Bacteroidetes,47NB4@768503|Cytophagia 976|Bacteroidetes G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM CMS3_k127_6560184_0 1121904.ARBP01000013_gene313 2.097e-112 385.0 COG3391@1|root,COG3391@2|Bacteria,4NH92@976|Bacteroidetes,47JVD@768503|Cytophagia 976|Bacteroidetes S NHL repeat containing protein - - - - - - - - - - - - NHL CMS3_k127_6560184_1 761193.Runsl_5342 7.77e-101 351.0 COG3055@1|root,COG3055@2|Bacteria,4NHHD@976|Bacteroidetes,47K9E@768503|Cytophagia 976|Bacteroidetes S Kelch repeat - - - - - - - - - - - - Kelch_1,Kelch_3,Kelch_4,Kelch_6 CMS3_k127_6560184_3 376686.Fjoh_4992 4.815e-50 186.0 COG4299@1|root,COG4299@2|Bacteria,4NIQV@976|Bacteroidetes,1I070@117743|Flavobacteriia,2NVI9@237|Flavobacterium 976|Bacteroidetes S Domain of unknown function (DUF5009) - - - - - - - - - - - - DUF1624,DUF5009 CMS3_k127_6569755_6 1042376.AFPK01000002_gene1789 1.075e-84 291.0 COG1408@1|root,COG1408@2|Bacteria,4NFCH@976|Bacteroidetes,1HWPQ@117743|Flavobacteriia,405YJ@61432|unclassified Flavobacteriaceae 976|Bacteroidetes S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07098 - - - - ko00000 - - - Metallophos CMS3_k127_6569755_1 1121859.KB890739_gene2782 6.024e-287 900.0 COG2010@1|root,COG2010@2|Bacteria,4NFP6@976|Bacteroidetes,47JRP@768503|Cytophagia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - CBM_6,PSCyt1,PSCyt2,PSD1 CMS3_k127_6569755_3 1121859.KB890739_gene2783 4.891e-244 760.0 COG3119@1|root,COG3119@2|Bacteria,4NGVK@976|Bacteroidetes,47K11@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_6569755_4 1121904.ARBP01000013_gene358 3.703e-121 405.0 COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia 976|Bacteroidetes S Planctomycete cytochrome C - - - - - - - - - - - - LRR_8,PSCyt1 CMS3_k127_6569755_0 1121904.ARBP01000001_gene5600 0.0 1247.0 COG3748@1|root,COG3748@2|Bacteria,4PN1Z@976|Bacteroidetes,47YB5@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1549) - - - - - - - - - - - - Laminin_G_3,PSCyt1,PSCyt2,PSD1 CMS3_k127_6569755_2 1121904.ARBP01000001_gene5601 1.448e-253 788.0 COG3119@1|root,COG3119@2|Bacteria,4PKKW@976|Bacteroidetes,47Y6A@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_6569755_7 1121094.KB894660_gene2701 1.717e-73 261.0 COG0470@1|root,COG0470@2|Bacteria,4NEYF@976|Bacteroidetes,2FPCQ@200643|Bacteroidia,4AMUD@815|Bacteroidaceae 976|Bacteroidetes L COG2812 DNA polymerase III gamma tau subunits holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 CMS3_k127_6569755_12 1313421.JHBV01000015_gene5759 3.358e-19 97.0 COG2067@1|root,COG2067@2|Bacteria,4NVVD@976|Bacteroidetes,1IZZC@117747|Sphingobacteriia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - OMP_b-brl CMS3_k127_6569755_13 1185876.BN8_02071 3.29e-17 92.0 COG2067@1|root,COG2067@2|Bacteria,4PK2U@976|Bacteroidetes,47QDY@768503|Cytophagia 976|Bacteroidetes I long-chain fatty acid transport protein - - - - - - - - - - - - - CMS3_k127_6569755_5 1121904.ARBP01000007_gene2927 1.795e-91 316.0 COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,47K9R@768503|Cytophagia 976|Bacteroidetes S LVIVD repeat - - - - - - - - - - - - LVIVD CMS3_k127_6569755_11 1250278.JQNQ01000001_gene1641 2.341e-26 118.0 28NZX@1|root,2ZBWN@2|Bacteria,4NMZA@976|Bacteroidetes,1I1IW@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6569755_8 1121481.AUAS01000005_gene1815 2.228e-72 264.0 COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,47M54@768503|Cytophagia 976|Bacteroidetes K Fibronectin-binding protein A N-terminus (FbpA) - - - - - - - - - - - - DUF814,FbpA CMS3_k127_6569755_10 1313301.AUGC01000017_gene812 1.241e-59 214.0 COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes 976|Bacteroidetes O Universal bacterial protein YeaZ yeaZ - - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 CMS3_k127_6569755_9 859657.RPSI07_mp1002 1.091e-59 214.0 COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,1KGY2@119060|Burkholderiaceae 28216|Betaproteobacteria M transferase - - - ko:K13012 - - - - ko00000,ko01005 - - - Bac_transf CMS3_k127_6572807_0 411154.GFO_2906 4.914e-104 357.0 COG4932@1|root,COG4932@2|Bacteria,4NK3C@976|Bacteroidetes,1I0WF@117743|Flavobacteriia 976|Bacteroidetes M oxidoreductase activity - - - - - - - - - - - - - CMS3_k127_6572807_1 1168034.FH5T_20610 7.913e-17 94.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - - CMS3_k127_6572807_2 1123276.KB893246_gene559 9.838e-08 55.0 COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47N4P@768503|Cytophagia 976|Bacteroidetes S Penicillin amidase - - 3.5.1.11 ko:K01434 ko00311,ko01130,map00311,map01130 - R02170 RC00166,RC00328 ko00000,ko00001,ko01000,ko01002 - - - Penicil_amidase CMS3_k127_6577831_1 1121012.AUKX01000001_gene1275 1.206e-129 426.0 COG3174@1|root,COG3174@2|Bacteria,4NKP6@976|Bacteroidetes,1HYVZ@117743|Flavobacteriia,23GC2@178469|Arenibacter 976|Bacteroidetes S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC CMS3_k127_6577831_0 880070.Cycma_0015 2.24e-166 535.0 COG2960@1|root,COG2960@2|Bacteria,4NFIK@976|Bacteroidetes,47N49@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH CMS3_k127_6577831_2 880070.Cycma_0014 1.312e-59 211.0 COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,4NI4S@976|Bacteroidetes,47M53@768503|Cytophagia 976|Bacteroidetes CL Protein of unknown function (DUF1595) - - - - - - - - - - - - PSCyt3,PSD2,PSD3,PSD4,PSD5 CMS3_k127_6588908_3 485917.Phep_2570 8.016e-75 264.0 COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1IVJ7@117747|Sphingobacteriia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6588908_1 1089550.ATTH01000001_gene1163 7.212e-115 378.0 COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,1FJ1D@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR CMS3_k127_6588908_5 1121364.ATVG01000004_gene314 8.556e-06 57.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,22KT0@1653|Corynebacteriaceae 201174|Actinobacteria O Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain pepD - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 CMS3_k127_6588908_2 1121904.ARBP01000004_gene847 4.017e-81 281.0 COG2870@1|root,COG2870@2|Bacteria,4NHUV@976|Bacteroidetes,47K45@768503|Cytophagia 976|Bacteroidetes M pfkB family carbohydrate kinase rfaE - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB CMS3_k127_6588908_0 929556.Solca_2091 5.697e-138 449.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,1INY0@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Aminotransferase class I and II aspC - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_6588908_4 984262.SGRA_0860 1.438e-44 168.0 COG1259@1|root,COG1259@2|Bacteria,4NGSW@976|Bacteroidetes,1IRH8@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Uncharacterised ACR, COG1259 - - - ko:K08999 - - - - ko00000 - - - DNase-RNase,UVR CMS3_k127_6592116_3 1380393.JHVP01000001_gene2458 1.456e-24 115.0 COG0739@1|root,COG3391@1|root,COG0739@2|Bacteria,COG3391@2|Bacteria,2HGM8@201174|Actinobacteria,4EWIS@85013|Frankiales 201174|Actinobacteria M heme binding - - 3.5.1.56 ko:K03418 ko00630,map00630 - R02509 RC00111,RC00731 ko00000,ko00001,ko01000 - - - - CMS3_k127_6592116_2 313606.M23134_01751 2.173e-63 224.0 COG0778@1|root,COG0778@2|Bacteria,4NMUE@976|Bacteroidetes,47PFV@768503|Cytophagia 976|Bacteroidetes C Nitroreductase family ydjA - - - - - - - - - - - Nitroreductase CMS3_k127_6592116_4 984262.SGRA_1775 1.962e-17 90.0 COG3117@1|root,COG3117@2|Bacteria,4NRIN@976|Bacteroidetes 976|Bacteroidetes S Lipopolysaccharide-assembly, LptC-related - - - - - - - - - - - - LptC CMS3_k127_6592116_1 313598.MED152_11469 4.315e-87 303.0 COG1253@1|root,COG1253@2|Bacteria,4NG0I@976|Bacteroidetes,1HWV0@117743|Flavobacteriia,3VV3V@52959|Polaribacter 976|Bacteroidetes P Transporter associated domain tlyC - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 CMS3_k127_6592116_0 760192.Halhy_2973 4.501e-205 652.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_6594452_2 1499967.BAYZ01000101_gene3603 7.532e-29 120.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation CP_0732 - - - - - - - - - - - Apolipoprotein,Cu_amine_oxidN1,LRR_5 CMS3_k127_6594452_0 1499967.BAYZ01000101_gene3604 7.687e-87 325.0 29UDS@1|root,30FQF@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_6594452_1 489825.LYNGBM3L_06070 8.553e-38 149.0 COG3500@1|root,COG3500@2|Bacteria,1GCWA@1117|Cyanobacteria,1HF6Y@1150|Oscillatoriales 1117|Cyanobacteria S Late control gene D protein - - - - - - - - - - - - - CMS3_k127_6600096_0 234267.Acid_4252 4.959e-54 203.0 COG0613@1|root,COG0613@2|Bacteria,3Y2US@57723|Acidobacteria 57723|Acidobacteria S PHP domain protein - - - - - - - - - - - - - CMS3_k127_6600096_1 313606.M23134_01898 9.12e-19 102.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria 2|Bacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8 CMS3_k127_6600096_2 500153.JOEK01000002_gene375 2.433e-12 77.0 COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria 201174|Actinobacteria G Glucose sorbosone - - - - - - - - - - - - CBM_6,DUF1080,GSDH,PKD,ThuA CMS3_k127_6633416_0 869213.JCM21142_12 1.993e-138 452.0 COG1757@1|root,COG1757@2|Bacteria,4NHP9@976|Bacteroidetes,47NR6@768503|Cytophagia 976|Bacteroidetes C Na+/H+ antiporter family - - - - - - - - - - - - Na_H_antiporter CMS3_k127_6633416_1 1237149.C900_00387 7.066e-125 424.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6634876_0 1120968.AUBX01000013_gene3439 1.121e-184 597.0 COG0488@1|root,COG0488@2|Bacteria,4NG1W@976|Bacteroidetes,47KHA@768503|Cytophagia 976|Bacteroidetes S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CMS3_k127_6634876_1 1124780.ANNU01000019_gene1764 1.206e-83 285.0 COG1974@1|root,COG1974@2|Bacteria,4PKQ7@976|Bacteroidetes,47P4U@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,Peptidase_S24 CMS3_k127_6634876_2 690850.Desaf_3069 4.754e-53 196.0 COG2173@1|root,COG2173@2|Bacteria,1N3QY@1224|Proteobacteria,42TQ8@68525|delta/epsilon subdivisions,2WNK8@28221|Deltaproteobacteria,2M9YV@213115|Desulfovibrionales 28221|Deltaproteobacteria M Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide ddpX - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 CMS3_k127_6634876_3 926562.Oweho_0344 1.309e-43 170.0 COG1934@1|root,COG1934@2|Bacteria,4PKT4@976|Bacteroidetes,1IKDV@117743|Flavobacteriia,2PAQU@246874|Cryomorphaceae 976|Bacteroidetes S OstA-like protein - - - - - - - - - - - - OstA_2 CMS3_k127_6651640_3 446462.Amir_4103 0.000958 45.0 COG2128@1|root,COG2128@2|Bacteria,2ICI6@201174|Actinobacteria,4E26I@85010|Pseudonocardiales 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD CMS3_k127_6651640_2 460265.Mnod_3197 1.654e-07 61.0 293J8@1|root,2ZR19@2|Bacteria,1R6Y4@1224|Proteobacteria,2U57A@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS3_k127_6651640_0 1396418.BATQ01000092_gene5858 7.213e-68 241.0 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator exsA GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031326,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0051596,GO:0060255,GO:0061727,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1903506,GO:2000112,GO:2001141 - ko:K20968 ko02025,map02025 - - - ko00000,ko00001,ko03000 - - - HTH_18 CMS3_k127_6651640_1 1121904.ARBP01000003_gene6147 8.931e-08 60.0 COG1595@1|root,COG1595@2|Bacteria,4NKX6@976|Bacteroidetes,47KQJ@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6686046_2 1089547.KB913013_gene3249 1.812e-10 70.0 2CJWV@1|root,2ZBKR@2|Bacteria,4NMFQ@976|Bacteroidetes,47PBB@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6686046_0 1492737.FEM08_05270 5.771e-36 140.0 COG0510@1|root,COG1257@1|root,COG0510@2|Bacteria,COG1257@2|Bacteria,4NGN1@976|Bacteroidetes,1INBK@117743|Flavobacteriia,2NYYX@237|Flavobacterium 976|Bacteroidetes I Hydroxymethylglutaryl-coenzyme A reductase - - 1.1.1.34 ko:K00021 ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976 M00095 R02082 RC00004,RC00644 ko00000,ko00001,ko00002,ko01000 - - - APH,HMG-CoA_red CMS3_k127_6686046_1 694427.Palpr_0366 2.101e-17 88.0 COG2832@1|root,COG2832@2|Bacteria,4NS6H@976|Bacteroidetes,2FSGM@200643|Bacteroidia,22YP7@171551|Porphyromonadaceae 976|Bacteroidetes S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 CMS3_k127_6686046_3 700598.Niako_5439 0.0002799 46.0 COG1100@1|root,COG1100@2|Bacteria 2|Bacteria S GTP binding - - - - - - - - - - - - AAA_24,DUF697,MMR_HSR1 CMS3_k127_6692727_0 1279009.ADICEAN_01073 1.964e-156 501.0 COG2273@1|root,COG3979@1|root,COG2273@2|Bacteria,COG3979@2|Bacteria,4NKMT@976|Bacteroidetes 976|Bacteroidetes G glycoside hydrolase, family - - - - - - - - - - - - F5_F8_type_C,Glyco_hydro_16 CMS3_k127_6692727_1 313606.M23134_04904 6.625e-80 276.0 COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,47K5K@768503|Cytophagia 976|Bacteroidetes G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin CMS3_k127_6693612_2 1565314.OA34_08200 2.449e-96 331.0 COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,42MH6@68525|delta/epsilon subdivisions,2YR4D@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CMS3_k127_6693612_0 867900.Celly_2625 2.278e-207 662.0 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,1HXV0@117743|Flavobacteriia,1F83R@104264|Cellulophaga 976|Bacteroidetes F COGs COG0367 Asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 CMS3_k127_6693612_1 1121904.ARBP01000002_gene6716 4.161e-101 342.0 COG0438@1|root,COG0438@2|Bacteria,4NE0W@976|Bacteroidetes,47NIW@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_6693612_5 1237149.C900_05476 2.439e-12 81.0 COG3391@1|root,COG3391@2|Bacteria,4NZAU@976|Bacteroidetes,47Y1X@768503|Cytophagia 976|Bacteroidetes DZ regulator of chromosome condensation, RCC1 - - - - - - - - - - - - - CMS3_k127_6693612_3 497964.CfE428DRAFT_1163 2.214e-53 215.0 COG3506@1|root,COG4254@1|root,COG3506@2|Bacteria,COG4254@2|Bacteria,46SQ1@74201|Verrucomicrobia 74201|Verrucomicrobia P Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - Laminin_G_3,Lyase_8,Lyase_N,Lyase_catalyt CMS3_k127_6693612_4 452637.Oter_2484 1.172e-13 85.0 2DBVG@1|root,2ZBB1@2|Bacteria,46VS7@74201|Verrucomicrobia,3K9TX@414999|Opitutae 414999|Opitutae - - - - - - - - - - - - - - - CMS3_k127_6695139_1 1121904.ARBP01000037_gene2056 2.939e-172 552.0 COG0591@1|root,COG0591@2|Bacteria,4NEF3@976|Bacteroidetes,47KNW@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_6695139_0 1121904.ARBP01000037_gene2055 1.173e-236 739.0 COG2407@1|root,COG2407@2|Bacteria,4NF0C@976|Bacteroidetes,47JET@768503|Cytophagia 976|Bacteroidetes G Catalyzes the conversion of L-arabinose to L-ribulose - - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Isome,Fucose_iso_C CMS3_k127_6695139_3 468059.AUHA01000002_gene38 2.888e-52 199.0 COG0451@1|root,COG0451@2|Bacteria,4NKKZ@976|Bacteroidetes 976|Bacteroidetes M Male sterility protein - - - - - - - - - - - - Epimerase CMS3_k127_6695139_2 643867.Ftrac_1628 1.864e-113 396.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,4NEHE@976|Bacteroidetes,47JHD@768503|Cytophagia 976|Bacteroidetes G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N CMS3_k127_6695139_4 1313421.JHBV01000032_gene1608 1.513e-37 151.0 2EIP2@1|root,33CEF@2|Bacteria 2|Bacteria S Uncharacterised nucleotidyltransferase - - - - - - - - - - - - NTP_transf_5 CMS3_k127_6698722_0 762903.Pedsa_0045 4.267e-218 739.0 COG1361@1|root,COG1470@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria 2|Bacteria S cell adhesion involved in biofilm formation - - - - - - - - - - - - CARDB,CHU_C,Calx-beta,CarboxypepD_reg,DUF11,Flg_new,HYR,PKD,SLH,SdrD_B,fn3 CMS3_k127_6698722_6 880073.Calab_1116 1.612e-14 89.0 COG0526@1|root,COG3693@1|root,COG0526@2|Bacteria,COG3693@2|Bacteria 2|Bacteria G endo-1,4-beta-xylanase activity - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - AhpC-TSA,Glyco_hydro_10,Glyco_hydro_39,Omp28 CMS3_k127_6698722_5 1122985.HMPREF1991_01471 8.798e-48 185.0 COG2207@1|root,COG2207@2|Bacteria,4NIJV@976|Bacteroidetes,2FU8W@200643|Bacteroidia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 CMS3_k127_6698722_4 1506583.JQJY01000007_gene4108 5.995e-49 188.0 COG2267@1|root,COG2267@2|Bacteria,4NIGT@976|Bacteroidetes,1I1MM@117743|Flavobacteriia,2P046@237|Flavobacterium 976|Bacteroidetes I Serine aminopeptidase, S33 - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Hydrolase_4 CMS3_k127_6698722_1 1313421.JHBV01000039_gene2715 4.331e-116 384.0 COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,1IVEN@117747|Sphingobacteriia 976|Bacteroidetes S Bestrophin, RFP-TM, chloride channel - - - ko:K08994 - - - - ko00000,ko02000 1.A.46.2 - - Bestrophin CMS3_k127_6698722_2 1144888.CM001467_gene764 2.016e-114 380.0 COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ATPase (AAA superfamily - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_6698722_3 143224.JQMD01000002_gene878 4.739e-111 362.0 2DB9P@1|root,2Z7Y1@2|Bacteria,4NHQN@976|Bacteroidetes,1HZIH@117743|Flavobacteriia 976|Bacteroidetes S Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_6702493_1 1250232.JQNJ01000001_gene90 6.324e-56 205.0 COG0845@1|root,COG0845@2|Bacteria,4NDW5@976|Bacteroidetes,1HXZJ@117743|Flavobacteriia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - HlyD_D23 CMS3_k127_6702493_2 264201.pc1991 7.815e-06 54.0 COG2849@1|root,COG2849@2|Bacteria,2JFW2@204428|Chlamydiae 204428|Chlamydiae S MORN repeat variant CP_1108 - - - - - - - - - - - MORN_2 CMS3_k127_6702493_0 700598.Niako_7343 2.036e-109 362.0 COG0583@1|root,COG0583@2|Bacteria,4NGZ5@976|Bacteroidetes,1INST@117747|Sphingobacteriia 976|Bacteroidetes K transcriptional regulator oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate CMS3_k127_6710405_0 643867.Ftrac_2299 3.691e-245 776.0 COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,47JE2@768503|Cytophagia 976|Bacteroidetes L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CMS3_k127_6710405_4 485918.Cpin_0433 5.723e-157 500.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia 976|Bacteroidetes S PFAM ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 CMS3_k127_6710405_11 1004149.AFOE01000048_gene4 8.585e-08 54.0 COG1236@1|root,COG1236@2|Bacteria,4NFN7@976|Bacteroidetes,1HZJP@117743|Flavobacteriia 976|Bacteroidetes J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07577 - - - - ko00000 - - - Lactamase_B CMS3_k127_6710405_10 633131.TR2A62_3699 6.455e-10 60.0 COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,2TQU5@28211|Alphaproteobacteria 28211|Alphaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing MA20_22065 - - ko:K07577 - - - - ko00000 - - - Lactamase_B CMS3_k127_6710405_6 1380600.AUYN01000010_gene883 5.952e-90 308.0 COG0457@1|root,COG0457@2|Bacteria,4NEYK@976|Bacteroidetes,1I0QJ@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911,TPR_2,TPR_8 CMS3_k127_6710405_2 313606.M23134_02851 2.079e-177 574.0 COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,47NUP@768503|Cytophagia 976|Bacteroidetes V Domain of unknown function (DUF3471) - - - - - - - - - - - - Beta-lactamase,DUF3471 CMS3_k127_6710405_5 926550.CLDAP_38230 1.61e-119 393.0 COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi 200795|Chloroflexi E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C CMS3_k127_6710405_7 322710.Avin_49360 3.665e-49 196.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1SI2P@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF5122,HemolysinCabind,Peptidase_M10_C CMS3_k127_6710405_8 1279009.ADICEAN_02967 2.243e-32 133.0 COG2010@1|root,COG3291@1|root,COG2010@2|Bacteria,COG3291@2|Bacteria,4NV3K@976|Bacteroidetes,47W7K@768503|Cytophagia 976|Bacteroidetes C Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_6710405_1 517418.Ctha_1724 5.914e-228 758.0 COG1404@1|root,COG1404@2|Bacteria,1FFAM@1090|Chlorobi 1090|Chlorobi O PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - Peptidase_S8 CMS3_k127_6710405_3 592029.DDD_1036 4.246e-161 527.0 COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1HY0T@117743|Flavobacteriia,3HJWX@363408|Nonlabens 976|Bacteroidetes F Na+ dependent nucleoside transporter N-terminus nupC - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N CMS3_k127_6710405_9 313606.M23134_01091 2.118e-13 73.0 COG0657@1|root,COG0657@2|Bacteria,4NM58@976|Bacteroidetes,47SS2@768503|Cytophagia 976|Bacteroidetes I Steryl acetyl hydrolase - - 3.1.1.83 ko:K01066,ko:K14731 ko00903,ko00930,ko01220,map00903,map00930,map01220 - R03751,R06390,R06391,R06392,R06393 RC00713,RC00983,RC01505 ko00000,ko00001,ko01000 - - - Abhydrolase_3 CMS3_k127_6712789_2 1121904.ARBP01000026_gene677 1.754e-24 111.0 COG4249@1|root,COG4249@2|Bacteria,4PM92@976|Bacteroidetes,47YMY@768503|Cytophagia 976|Bacteroidetes S Caspase domain - - - - - - - - - - - - Peptidase_C14 CMS3_k127_6712789_1 349521.HCH_06118 2.319e-26 121.0 2EC04@1|root,335ZE@2|Bacteria,1NA1N@1224|Proteobacteria 1224|Proteobacteria S Protein of unknown function (DUF1266) - - - - - - - - - - - - DUF1266 CMS3_k127_6712789_0 1121875.KB907546_gene2622 1.123e-187 601.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,1HWYF@117743|Flavobacteriia 976|Bacteroidetes C Protein of unknown function (DUF1549) - - - - - - - - - - - - Laminin_G_3,PSCyt1,PSCyt2,PSD1 CMS3_k127_6714403_5 1196323.ALKF01000196_gene2182 1.319e-74 254.0 COG0528@1|root,COG0528@2|Bacteria,1U09A@1239|Firmicutes,4HBRM@91061|Bacilli,26QVG@186822|Paenibacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase CMS3_k127_6714403_2 411154.GFO_2861 1.425e-137 451.0 COG0773@1|root,COG0773@2|Bacteria,4NF99@976|Bacteroidetes,1HXZ0@117743|Flavobacteriia 976|Bacteroidetes M Peptidoglycan synthetase mpl - 6.3.2.45,6.3.2.8 ko:K01924,ko:K02558 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS3_k127_6714403_1 760192.Halhy_3877 1.495e-275 866.0 COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,4NGJ4@976|Bacteroidetes,1IPE7@117747|Sphingobacteriia 976|Bacteroidetes G HAD-superfamily hydrolase, subfamily IIB otsB - 2.4.1.15,3.1.3.12 ko:K16055 ko00500,ko01100,map00500,map01100 - R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20,Trehalose_PPase CMS3_k127_6714403_6 1121904.ARBP01000004_gene1088 2.742e-39 151.0 2CM2H@1|root,32SDI@2|Bacteria,4NSAF@976|Bacteroidetes,47R71@768503|Cytophagia 976|Bacteroidetes S Putative lumazine-binding - - - - - - - - - - - - Lumazine_bd_2 CMS3_k127_6714403_3 1121904.ARBP01000012_gene1244 5.252e-78 274.0 28M5H@1|root,2ZAJ9@2|Bacteria,4NESS@976|Bacteroidetes,47NNA@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6714403_4 935836.JAEL01000094_gene3351 2.299e-77 266.0 COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4HCA1@91061|Bacilli,1ZCCC@1386|Bacillus 91061|Bacilli S Transport and Golgi organisation 2 - - - - - - - - - - - - TANGO2 CMS3_k127_6714403_0 1313421.JHBV01000025_gene1038 7.358e-288 905.0 COG4953@1|root,COG4953@2|Bacteria,4NEG5@976|Bacteroidetes,1IP6N@117747|Sphingobacteriia 976|Bacteroidetes M Penicillin-binding Protein pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase CMS3_k127_6714403_7 869213.JCM21142_83090 4.175e-10 64.0 COG0706@1|root,COG0706@2|Bacteria,4NESJ@976|Bacteroidetes,47KF7@768503|Cytophagia 976|Bacteroidetes U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas CMS3_k127_6715353_5 1296416.JACB01000044_gene4986 2.059e-23 108.0 2A7T4@1|root,30WS7@2|Bacteria,4PA5K@976|Bacteroidetes,1IHJ1@117743|Flavobacteriia,2YH3N@290174|Aquimarina 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6715353_3 1443665.JACA01000041_gene1619 9.934e-74 261.0 COG2267@1|root,COG2267@2|Bacteria,4NKKQ@976|Bacteroidetes,1I718@117743|Flavobacteriia,2YI1X@290174|Aquimarina 976|Bacteroidetes I Prolyl oligopeptidase family - - - - - - - - - - - - Hydrolase_4 CMS3_k127_6715353_1 589865.DaAHT2_0743 1.533e-91 305.0 COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,42MYK@68525|delta/epsilon subdivisions,2WN3P@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung - 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CMS3_k127_6715353_2 1123024.AUII01000006_gene4635 2.246e-78 271.0 2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - CMS3_k127_6715353_0 693979.Bache_3205 8.932e-144 486.0 COG1629@1|root,COG4932@1|root,COG4771@2|Bacteria,COG4932@2|Bacteria,4NEIG@976|Bacteroidetes,2FM1K@200643|Bacteroidia,4APIA@815|Bacteroidaceae 976|Bacteroidetes P Outer membrane protein beta-barrel family - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug CMS3_k127_6715353_4 525257.HMPREF0204_10466 3.7e-52 190.0 COG0642@1|root,COG0642@2|Bacteria,4NEW4@976|Bacteroidetes,1HZ62@117743|Flavobacteriia,3ZT64@59732|Chryseobacterium 976|Bacteroidetes T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA CMS3_k127_6731106_0 1123248.KB893317_gene4292 3.162e-220 692.0 COG0613@1|root,COG0613@2|Bacteria,4PN3D@976|Bacteroidetes 976|Bacteroidetes S PHP domain protein - - - - - - - - - - - - - CMS3_k127_6731106_5 1499967.BAYZ01000013_gene6434 9.766e-93 313.0 COG0329@1|root,COG0329@2|Bacteria 2|Bacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS3_k127_6731106_4 1408473.JHXO01000007_gene755 2.885e-109 364.0 COG3616@1|root,COG3616@2|Bacteria,4NF5K@976|Bacteroidetes,2FX5F@200643|Bacteroidia 976|Bacteroidetes E Putative serine dehydratase domain - - - - - - - - - - - - Ala_racemase_N,D-ser_dehydrat CMS3_k127_6731106_3 984262.SGRA_2533 1.584e-114 389.0 COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IQZU@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase M1 - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 CMS3_k127_6731106_6 1122176.KB903539_gene1392 3.944e-84 282.0 COG2318@1|root,COG2318@2|Bacteria,4NMJ9@976|Bacteroidetes,1IRU4@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1572) - - - - - - - - - - - - DUF1572 CMS3_k127_6731106_13 929556.Solca_2017 5.71e-15 85.0 2DJDC@1|root,32UCS@2|Bacteria,4NTR3@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4905) - - - - - - - - - - - - DUF4905 CMS3_k127_6731106_10 1279009.ADICEAN_03098 4.253e-65 226.0 COG1595@1|root,COG1595@2|Bacteria,4NMM3@976|Bacteroidetes,47KPZ@768503|Cytophagia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily sigR_3 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6731106_2 1279009.ADICEAN_03100 9.793e-120 391.0 COG1562@1|root,COG1562@2|Bacteria,4NEIK@976|Bacteroidetes,47J9F@768503|Cytophagia 976|Bacteroidetes I PFAM Squalene phytoene synthase crtB - - - - - - - - - - - SQS_PSY CMS3_k127_6731106_9 866536.Belba_0848 5.747e-66 232.0 arCOG05416@1|root,2ZZTD@2|Bacteria,4NNMY@976|Bacteroidetes,47Q57@768503|Cytophagia 976|Bacteroidetes S lycopene cyclase - - - - - - - - - - - - - CMS3_k127_6731106_1 1120965.AUBV01000014_gene1233 3.264e-122 398.0 COG0761@1|root,COG0761@2|Bacteria,4NDUX@976|Bacteroidetes,47M59@768503|Cytophagia 976|Bacteroidetes IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB CMS3_k127_6731106_7 926556.Echvi_1481 4.8e-81 276.0 COG3239@1|root,COG3239@2|Bacteria,4NHGR@976|Bacteroidetes,47MNE@768503|Cytophagia 976|Bacteroidetes I fatty acid desaturase - - - ko:K09836 ko00906,map00906 - R05345,R07549,R07557,R07563,R07564,R07565,R07566,R07567,R07571,R07573 RC01900,RC01991 ko00000,ko00001 - - - FA_desaturase CMS3_k127_6731106_14 386456.JQKN01000009_gene1161 9.582e-06 58.0 COG1520@1|root,COG3291@1|root,arCOG02516@1|root,arCOG02552@1|root,arCOG02492@2157|Archaea,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG02552@2157|Archaea,2Y7Q0@28890|Euryarchaeota 28890|Euryarchaeota KLT COG1520 FOG WD40-like repeat - - - - - - - - - - - - CHB_HEX_C_1,PKD,PQQ_3 CMS3_k127_6731106_12 515635.Dtur_1286 5.011e-48 192.0 COG1520@1|root,COG1520@2|Bacteria 2|Bacteria S amino acid activation for nonribosomal peptide biosynthetic process - - - - - - - - - - - - DUF5122 CMS3_k127_6731106_8 1408813.AYMG01000003_gene2845 1.036e-66 237.0 COG2045@1|root,COG2045@2|Bacteria,4NG1A@976|Bacteroidetes,1IPNP@117747|Sphingobacteriia 976|Bacteroidetes H Belongs to the ComB family comB - 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 - - - 2-ph_phosp CMS3_k127_6731106_11 1042376.AFPK01000038_gene586 1.429e-54 194.0 28NYH@1|root,2ZBVN@2|Bacteria,4NMB2@976|Bacteroidetes,1I177@117743|Flavobacteriia,406D2@61432|unclassified Flavobacteriaceae 976|Bacteroidetes S Disulphide isomerase - - - - - - - - - - - - Disulph_isomer CMS3_k127_674527_3 755732.Fluta_2380 1.709e-27 117.0 COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4NFZB@976|Bacteroidetes,1HX37@117743|Flavobacteriia,2PBHB@246874|Cryomorphaceae 976|Bacteroidetes T Y_Y_Y domain - - - - - - - - - - - - HATPase_c,His_kinase,Reg_prop,Y_Y_Y CMS3_k127_674527_1 1408433.JHXV01000007_gene2930 6.353e-165 548.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,1IJNJ@117743|Flavobacteriia,2PC6F@246874|Cryomorphaceae 976|Bacteroidetes P Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarbopepD_reg_2,STN CMS3_k127_674527_0 616991.JPOO01000001_gene3086 0.0 1246.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,23HWE@178469|Arenibacter 976|Bacteroidetes P TonB dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_674527_2 1121011.AUCB01000015_gene60 2.121e-120 393.0 COG1395@1|root,COG1395@2|Bacteria,4NHQT@976|Bacteroidetes,1IJAX@117743|Flavobacteriia,23I2G@178469|Arenibacter 976|Bacteroidetes K SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_6755334_1 1313421.JHBV01000015_gene5755 4.814e-41 162.0 COG0265@1|root,COG3209@1|root,COG3291@1|root,COG5337@1|root,COG0265@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria 2|Bacteria M Spore coat protein CotH - - 3.4.21.107,3.4.21.50 ko:K01337,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - Collagen,CotH,Fn3_assoc,LTD CMS3_k127_6755334_0 760192.Halhy_0186 4.978e-123 411.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia 976|Bacteroidetes O COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 CMS3_k127_6755334_2 941449.dsx2_3258 2.342e-11 68.0 COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2M9HB@213115|Desulfovibrionales 28221|Deltaproteobacteria S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_6760877_3 1121904.ARBP01000003_gene6244 3.5e-134 435.0 COG1082@1|root,COG1082@2|Bacteria,4NFS5@976|Bacteroidetes,47NAA@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 - - - AP_endonuc_2 CMS3_k127_6760877_1 1121904.ARBP01000007_gene2944 2.668e-196 620.0 COG0673@1|root,COG0673@2|Bacteria,4NF9M@976|Bacteroidetes,47KYK@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_6760877_4 1449063.JMLS01000024_gene3694 1.418e-112 368.0 COG0684@1|root,COG0684@2|Bacteria,1TSK7@1239|Firmicutes 1239|Firmicutes H Aldolase/RraA - - - - - - - - - - - - RraA-like CMS3_k127_6760877_0 1237149.C900_03765 6.122e-198 625.0 COG1748@1|root,COG1748@2|Bacteria,4NFM8@976|Bacteroidetes,47MT4@768503|Cytophagia 976|Bacteroidetes E Saccharopine dehydrogenase - - 1.5.1.10,1.5.1.7 ko:K00290,ko:K00293 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715,R02315 RC00215,RC00217,RC00225,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP CMS3_k127_6760877_2 869213.JCM21142_93626 3.914e-182 579.0 COG0165@1|root,COG0165@2|Bacteria,4NFCY@976|Bacteroidetes,47JA3@768503|Cytophagia 976|Bacteroidetes E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Lyase_1 CMS3_k127_6767763_1 483219.LILAB_10770 1.163e-77 280.0 COG0318@1|root,COG0318@2|Bacteria,1PH7B@1224|Proteobacteria,42TTG@68525|delta/epsilon subdivisions,2WQEX@28221|Deltaproteobacteria,2YU8V@29|Myxococcales 28221|Deltaproteobacteria IQ GH3 auxin-responsive promoter - - - - - - - - - - - - GH3 CMS3_k127_6767763_0 1107311.Q767_10540 1.546e-95 344.0 COG4992@1|root,COG5322@1|root,COG4992@2|Bacteria,COG5322@2|Bacteria 2|Bacteria GT oxidoreductase activity - - 2.6.1.11,2.6.1.13,2.6.1.17,2.6.1.82 ko:K00819,ko:K00821,ko:K09251 ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00667,R01155,R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3,G3P_acyltransf,Shikimate_DH CMS3_k127_6767763_2 1123009.AUID01000005_gene1558 2.89e-06 59.0 COG3146@1|root,COG3146@2|Bacteria,1V5S7@1239|Firmicutes,24HQ6@186801|Clostridia 186801|Clostridia S Protein conserved in bacteria - - - - - - - - - - - - Acetyltransf_6 CMS3_k127_6778590_2 1123277.KB893206_gene3442 3.376e-46 179.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes 1123277.KB893206_gene3442|- P TonB-linked outer membrane protein, SusC RagA family - - - - - - - - - - - - - CMS3_k127_6778590_3 504472.Slin_6609 2.607e-16 87.0 COG1595@1|root,COG1595@2|Bacteria,4NP0R@976|Bacteroidetes,47Q39@768503|Cytophagia 976|Bacteroidetes K RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6778590_0 1049564.TevJSym_bb00050 4.603e-258 811.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases korA - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N CMS3_k127_6778590_1 1049564.TevJSym_bb00040 1.194e-107 357.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria C COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit korB - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C CMS3_k127_677947_2 880071.Fleli_1650 7.52e-41 155.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47NPA@768503|Cytophagia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS3_k127_677947_1 1121904.ARBP01000005_gene4863 9.1e-88 303.0 COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes,47P9V@768503|Cytophagia 976|Bacteroidetes M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - HlyD_3,HlyD_D23 CMS3_k127_677947_3 1122176.KB903565_gene3350 1.022e-31 128.0 COG0526@1|root,COG0526@2|Bacteria,4PKQI@976|Bacteroidetes,1ITPA@117747|Sphingobacteriia 976|Bacteroidetes O Thioredoxin - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CMS3_k127_677947_0 762903.Pedsa_0994 3.556e-180 570.0 COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia 976|Bacteroidetes G peptidase M42 frvX - - - - - - - - - - - Peptidase_M42 CMS3_k127_6781262_3 1235803.C825_03610 9.567e-35 136.0 COG0101@1|root,COG0101@2|Bacteria,4NFDC@976|Bacteroidetes,2FP2H@200643|Bacteroidia,22WF1@171551|Porphyromonadaceae 976|Bacteroidetes J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 CMS3_k127_6781262_1 926549.KI421517_gene3550 3.273e-60 215.0 COG2518@1|root,COG2518@2|Bacteria,4NFCU@976|Bacteroidetes,47P7V@768503|Cytophagia 976|Bacteroidetes J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT CMS3_k127_6781262_0 714943.Mucpa_1281 0.0 1244.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,1INQX@117747|Sphingobacteriia 976|Bacteroidetes E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5,GDC-P CMS3_k127_6781262_2 929562.Emtol_4017 1.422e-42 175.0 28KQM@1|root,2ZA8D@2|Bacteria,4NG3K@976|Bacteroidetes,47XIW@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6781603_4 760192.Halhy_2760 6.389e-76 257.0 COG0110@1|root,COG0110@2|Bacteria,4NENC@976|Bacteroidetes,1INZ0@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Bacterial transferase hexapeptide (three repeats) - - 2.3.1.201 ko:K13018 ko00520,map00520 - R10100 RC00004,RC00166 ko00000,ko00001,ko01000,ko01005 - - - Hexapep,Hexapep_2 CMS3_k127_6781603_2 385682.AFSL01000015_gene2677 4.052e-142 459.0 COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,2FR8Q@200643|Bacteroidia,3XJ0K@558415|Marinilabiliaceae 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - 1.1.1.335 ko:K13016 ko00520,map00520 - R10140 RC00182 ko00000,ko00001,ko01000,ko01005 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_6781603_3 485918.Cpin_2226 2.593e-138 452.0 COG0489@1|root,COG0489@2|Bacteria,4NF5I@976|Bacteroidetes,1IQKF@117747|Sphingobacteriia 976|Bacteroidetes D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA CMS3_k127_6781603_0 1124780.ANNU01000025_gene3340 0.0 1050.0 COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,47JGX@768503|Cytophagia 976|Bacteroidetes MU WD40-like Beta Propeller Repeat - - - - - - - - - - - - BSP,PD40 CMS3_k127_6781603_5 694427.Palpr_2150 1.12e-44 167.0 COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,2FUYE@200643|Bacteroidia,22YQH@171551|Porphyromonadaceae 976|Bacteroidetes O Belongs to the small heat shock protein (HSP20) family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS3_k127_6781603_1 760192.Halhy_0186 1.778e-187 598.0 COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1INQ7@117747|Sphingobacteriia 976|Bacteroidetes O COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain - - - - - - - - - - - - PDZ_1,PDZ_2,Trypsin_2 CMS3_k127_6802560_0 243265.plu1484 1.111e-90 302.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria 1236|Gammaproteobacteria H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iUTI89_1310.UTI89_C0772,iZ_1308.Z0993 Aminotran_3 CMS3_k127_6802560_2 526227.Mesil_3283 0.000154 49.0 COG2002@1|root,COG2002@2|Bacteria 2|Bacteria K toxin-antitoxin pair type II binding - - - ko:K06284 - - - - ko00000,ko03000 - - - ABC_tran,MazE_antitoxin CMS3_k127_6802560_1 573370.DMR_00660 1.554e-14 79.0 COG1848@1|root,COG1848@2|Bacteria,1PBM6@1224|Proteobacteria,43ECN@68525|delta/epsilon subdivisions,2X0C7@28221|Deltaproteobacteria,2MBSV@213115|Desulfovibrionales 28221|Deltaproteobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase vapC - - - - - - - - - - - PIN CMS3_k127_6803791_0 1239962.C943_00620 1.215e-06 53.0 COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,47JFQ@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_6806590_8 1453500.AT05_05935 2.316e-27 115.0 COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes,1I376@117743|Flavobacteriia 976|Bacteroidetes O Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C CMS3_k127_6806590_9 1121930.AQXG01000009_gene270 1.047e-26 115.0 COG0545@1|root,COG0545@2|Bacteria,4NQJS@976|Bacteroidetes 976|Bacteroidetes O Peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K03772 - - - - ko00000,ko01000,ko03110 - - - FKBP_C CMS3_k127_6806590_0 1121904.ARBP01000002_gene7120 1.016e-172 552.0 COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,47JWT@768503|Cytophagia 976|Bacteroidetes S integral membrane protein - - - - - - - - - - - - DUF819 CMS3_k127_6806590_4 383372.Rcas_3215 4.006e-95 323.0 COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi,377Y3@32061|Chloroflexia 32061|Chloroflexia S PFAM oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_6806590_2 1048983.EL17_06345 8.668e-124 405.0 COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,47KXF@768503|Cytophagia 976|Bacteroidetes E Threonine aldolase ltaA - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase CMS3_k127_6806590_11 390989.JOEG01000025_gene47 1.503e-08 62.0 COG1983@1|root,COG1983@2|Bacteria,2IRZU@201174|Actinobacteria,4DFHJ@85008|Micromonosporales 201174|Actinobacteria KT PspC domain - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC CMS3_k127_6806590_5 1122179.KB890438_gene1566 2.666e-66 237.0 COG0501@1|root,COG0501@2|Bacteria,4NT8D@976|Bacteroidetes 976|Bacteroidetes O Zn-dependent protease with chaperone function - - - - - - - - - - - - Peptidase_M48,zf-ribbon_3 CMS3_k127_6806590_7 36875.HQ29_04535 7.002e-31 130.0 COG1215@1|root,COG1215@2|Bacteria,4NQWJ@976|Bacteroidetes,2FQJ6@200643|Bacteroidia,230NM@171551|Porphyromonadaceae 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_6806590_3 1227739.Hsw_0104 2.366e-104 368.0 COG1287@1|root,COG1287@2|Bacteria,4NUWQ@976|Bacteroidetes,47W78@768503|Cytophagia 976|Bacteroidetes S oligosaccharyl transferase activity - - - - - - - - - - - - - CMS3_k127_6806590_6 1121904.ARBP01000012_gene1219 1.513e-49 189.0 2E676@1|root,330VQ@2|Bacteria,4NWHJ@976|Bacteroidetes,47SVQ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6806590_1 1237149.C900_02752 2.772e-157 508.0 COG0569@1|root,COG0569@2|Bacteria,4NE31@976|Bacteroidetes,47NY5@768503|Cytophagia 976|Bacteroidetes P TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N CMS3_k127_6806590_10 1333998.M2A_2033 3.049e-13 72.0 COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,2TW4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS3_k127_6806734_5 1123278.KB893389_gene4217 6.764e-08 62.0 COG2834@1|root,COG2834@2|Bacteria,4NFYQ@976|Bacteroidetes,47N94@768503|Cytophagia 976|Bacteroidetes M Domain of unknown function (DUF4292) - - - - - - - - - - - - DUF4292 CMS3_k127_6806734_3 1347393.HG726019_gene8001 7.282e-33 145.0 COG0457@1|root,COG0457@2|Bacteria,4NDVW@976|Bacteroidetes,2FMY8@200643|Bacteroidia,4AMTE@815|Bacteroidaceae 976|Bacteroidetes S Tetratricopeptide repeat protein - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 CMS3_k127_6806734_1 742767.HMPREF9456_02470 8.573e-61 213.0 COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes,2FR7A@200643|Bacteroidia,22XVH@171551|Porphyromonadaceae 976|Bacteroidetes F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase CMS3_k127_6806734_2 1121897.AUGO01000002_gene2230 5.008e-35 136.0 COG2154@1|root,COG2154@2|Bacteria,4NS9U@976|Bacteroidetes,1I40R@117743|Flavobacteriia,2NX4M@237|Flavobacterium 976|Bacteroidetes H Pterin 4 alpha carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a CMS3_k127_6806734_0 1123248.KB893321_gene458 1.153e-120 408.0 COG3419@1|root,COG3419@2|Bacteria 2|Bacteria NU Tfp pilus assembly protein tip-associated adhesin pilY1 - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC,VWA_2 CMS3_k127_6806734_4 880071.Fleli_1566 6.179e-28 123.0 COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,47R1B@768503|Cytophagia 976|Bacteroidetes M Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 CMS3_k127_681208_1 1121104.AQXH01000008_gene2388 2.516e-90 305.0 COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,1IR8M@117747|Sphingobacteriia 976|Bacteroidetes J Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans CMS3_k127_681208_3 706587.Desti_1880 1.484e-40 169.0 COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WJRA@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Histidine kinase - - - - - - - - - - - - DUF3365,HATPase_c,HisKA,PAS_4,PAS_9 CMS3_k127_681208_0 1313421.JHBV01000039_gene2667 2.849e-103 347.0 COG1594@1|root,COG1594@2|Bacteria,4PKAQ@976|Bacteroidetes,1J0UN@117747|Sphingobacteriia 976|Bacteroidetes K Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - - - - - - - - - - - - CMS3_k127_681208_2 706436.HMPREF9074_08404 3.564e-44 166.0 COG5263@1|root,COG5263@2|Bacteria,4NJ6B@976|Bacteroidetes,1HX7Q@117743|Flavobacteriia,1ETIA@1016|Capnocytophaga 976|Bacteroidetes S WG containing repeat - - - - - - - - - - - - WG_beta_rep CMS3_k127_6816744_1 414684.RC1_3175 1.67e-79 267.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria 28211|Alphaproteobacteria EU COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_6816744_2 376686.Fjoh_4266 1.451e-75 265.0 COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,1HYAU@117743|Flavobacteriia,2NUG1@237|Flavobacterium 976|Bacteroidetes I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 CMS3_k127_6816744_0 761193.Runsl_0627 1.534e-103 350.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6W@976|Bacteroidetes,47K4F@768503|Cytophagia 976|Bacteroidetes CG Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS3_k127_6820206_2 398720.MED217_11629 1.472e-53 190.0 COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,1HWN3@117743|Flavobacteriia,2XJ1Y@283735|Leeuwenhoekiella 976|Bacteroidetes F NUDIX domain - - - - - - - - - - - - NUDIX CMS3_k127_6820206_7 1117314.PCIT_03174 4.452e-08 57.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Transposase - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_3 CMS3_k127_6820206_5 1121287.AUMU01000021_gene577 8.563e-21 94.0 COG2801@1|root,COG2801@2|Bacteria,4NIBY@976|Bacteroidetes,1I9F8@117743|Flavobacteriia 976|Bacteroidetes L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve_3 CMS3_k127_6820206_1 1124780.ANNU01000081_gene2569 1.23e-72 250.0 COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,47QA2@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_6820206_6 1250006.JHZZ01000001_gene386 7.097e-14 73.0 COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia 976|Bacteroidetes Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 CMS3_k127_6820206_3 1250232.JQNJ01000001_gene3934 1.5e-38 148.0 COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1I3K8@117743|Flavobacteriia 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_6820206_0 1296415.JACC01000006_gene1509 6.506e-88 306.0 COG2960@1|root,COG2960@2|Bacteria,4NI9S@976|Bacteroidetes,1ICN0@117743|Flavobacteriia,2YKN6@290174|Aquimarina 976|Bacteroidetes M long-chain fatty acid transporting porin activity - - - - - - - - - - - - - CMS3_k127_6820206_4 1123248.KB893328_gene917 2.888e-21 96.0 COG3245@1|root,COG3245@2|Bacteria,4NRNS@976|Bacteroidetes,1IZF9@117747|Sphingobacteriia 976|Bacteroidetes C cytochrome - - - - - - - - - - - - - CMS3_k127_6820206_8 1107311.Q767_02725 8.726e-06 53.0 2A9DB@1|root,30YIH@2|Bacteria,4PCCI@976|Bacteroidetes,1ICZ6@117743|Flavobacteriia,2NWA7@237|Flavobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6823618_9 517418.Ctha_1735 1.925e-14 76.0 COG4663@1|root,COG4663@2|Bacteria,1FDID@1090|Chlorobi 1090|Chlorobi C PFAM TRAP dicarboxylate transporter- DctP subunit - - - - - - - - - - - - DctP CMS3_k127_6823618_2 1121904.ARBP01000019_gene2813 5.194e-166 530.0 COG0476@1|root,COG0476@2|Bacteria,4NFUD@976|Bacteroidetes,47KG8@768503|Cytophagia 976|Bacteroidetes H MoeZ MoeB domain moeZ - 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF CMS3_k127_6823618_4 1237149.C900_05463 2.129e-60 217.0 COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,47KPR@768503|Cytophagia 976|Bacteroidetes EH Reduction of activated sulfate into sulfite cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct CMS3_k127_6823618_3 1336803.PHEL49_2008 4.593e-148 484.0 COG0737@1|root,COG0737@2|Bacteria,4PH22@976|Bacteroidetes,1IMAK@117743|Flavobacteriia,3VVGS@52959|Polaribacter 976|Bacteroidetes F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C,Metallophos CMS3_k127_6823618_0 1120966.AUBU01000002_gene2083 1.977e-195 614.0 COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,47JY2@768503|Cytophagia 976|Bacteroidetes E PFAM Cys Met metabolism PLP-dependent enzyme metC - 2.5.1.48,4.4.1.1,4.4.1.8 ko:K01739,ko:K01758,ko:K01760 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00338 R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366 RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Cys_Met_Meta_PP CMS3_k127_6823618_7 1089550.ATTH01000001_gene2385 8.582e-27 122.0 28I6D@1|root,2Z89E@2|Bacteria,4NIIX@976|Bacteroidetes,1FJ85@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S EcsC protein family - - - - - - - - - - - - EcsC CMS3_k127_6823618_6 143224.JQMD01000002_gene988 1.904e-47 176.0 2B8X8@1|root,3227K@2|Bacteria,4NQKU@976|Bacteroidetes,1I3SR@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6823618_10 1296415.JACC01000003_gene3160 5.376e-11 72.0 COG0736@1|root,COG0736@2|Bacteria,4NSJM@976|Bacteroidetes,1I4IR@117743|Flavobacteriia,2YJ8D@290174|Aquimarina 976|Bacteroidetes I 4'-phosphopantetheinyl transferase superfamily - - - - - - - - - - - - ACPS CMS3_k127_6823618_8 1296415.JACC01000003_gene3159 6.507e-22 98.0 COG0236@1|root,COG0236@2|Bacteria,4NUSD@976|Bacteroidetes,1I5HU@117743|Flavobacteriia,2YJYF@290174|Aquimarina 976|Bacteroidetes IQ Phosphopantetheine attachment site - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_6823618_1 1121890.AUDO01000003_gene1867 3.649e-170 544.0 COG0304@1|root,COG0304@2|Bacteria,4NDXP@976|Bacteroidetes,1HXYM@117743|Flavobacteriia,2NU5Z@237|Flavobacterium 976|Bacteroidetes IQ Belongs to the beta-ketoacyl-ACP synthases family fabB - - - - - - - - - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_6823618_5 485918.Cpin_5031 3.466e-48 176.0 COG0764@1|root,COG0764@2|Bacteria,4NQ8S@976|Bacteroidetes,1ISU8@117747|Sphingobacteriia 976|Bacteroidetes I dehydratase fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CMS3_k127_683510_0 661478.OP10G_3057 3.913e-75 267.0 COG2070@1|root,COG2070@2|Bacteria 2|Bacteria S nitronate monooxygenase activity npd GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO CMS3_k127_683510_1 1237149.C900_00070 1.559e-44 182.0 COG0457@1|root,COG3920@1|root,COG0457@2|Bacteria,COG3920@2|Bacteria,4NINT@976|Bacteroidetes,47MIH@768503|Cytophagia 976|Bacteroidetes T HWE histidine kinase - - - - - - - - - - - - HATPase_c,HATPase_c_2,HisKA_2,TPR_12,TPR_8 CMS3_k127_6840845_7 1121904.ARBP01000006_gene3679 2.535e-84 290.0 COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,47JVG@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran CMS3_k127_6840845_2 1121904.ARBP01000006_gene3678 1.707e-192 618.0 COG1132@1|root,COG1132@2|Bacteria,4NDY6@976|Bacteroidetes,47JPX@768503|Cytophagia 976|Bacteroidetes V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CMS3_k127_6840845_3 1123008.KB905706_gene865 2.985e-184 603.0 COG3408@1|root,COG3408@2|Bacteria,4PMQ8@976|Bacteroidetes,2FQR0@200643|Bacteroidia,2301J@171551|Porphyromonadaceae 976|Bacteroidetes G Bacterial alpha-L-rhamnosidase C-terminal domain - - - - - - - - - - - - Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C CMS3_k127_6840845_9 1392498.JQLH01000001_gene1872 9.404e-43 164.0 COG1595@1|root,COG1595@2|Bacteria,4NVCP@976|Bacteroidetes,1IEHT@117743|Flavobacteriia,2PHYH@252356|Maribacter 976|Bacteroidetes K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6840845_8 1336803.PHEL49_1730 9.845e-73 257.0 COG3712@1|root,COG3712@2|Bacteria,4NQUV@976|Bacteroidetes,1I1HJ@117743|Flavobacteriia,3VX63@52959|Polaribacter 976|Bacteroidetes PT FecR protein - - - - - - - - - - - - DUF4974,FecR CMS3_k127_6840845_0 616991.JPOO01000001_gene4255 0.0 1165.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,1IJ92@117743|Flavobacteriia 976|Bacteroidetes H Outer membrane receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_6840845_4 616991.JPOO01000001_gene4256 6.66e-181 579.0 COG0702@1|root,COG0702@2|Bacteria,4NEDB@976|Bacteroidetes,1I30S@117743|Flavobacteriia,23FX1@178469|Arenibacter 976|Bacteroidetes GM SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_6840845_1 641524.ADICYQ_5476 5.942e-252 793.0 COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,47YCZ@768503|Cytophagia 976|Bacteroidetes C HI0933-like protein - - - - - - - - - - - - FAD_oxidored CMS3_k127_6840845_6 616991.JPOO01000001_gene2851 1.621e-134 440.0 COG4409@1|root,COG4409@2|Bacteria,4NIWA@976|Bacteroidetes 976|Bacteroidetes G BNR repeat-like domain - - - - - - - - - - - - BNR_2 CMS3_k127_6840845_5 880070.Cycma_3768 3.514e-172 548.0 COG4409@1|root,COG4409@2|Bacteria,4NIWA@976|Bacteroidetes 976|Bacteroidetes G BNR repeat-like domain - - - - - - - - - - - - BNR_2 CMS3_k127_6841092_1 760192.Halhy_4648 1.422e-76 269.0 COG0457@1|root,COG0457@2|Bacteria,4NGID@976|Bacteroidetes 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_6841092_0 1124780.ANNU01000045_gene2299 2.874e-197 635.0 COG1501@1|root,COG1523@1|root,COG1501@2|Bacteria,COG1523@2|Bacteria,4NE1H@976|Bacteroidetes,47NQ6@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Esterase,Gal_mutarotas_2,Glyco_hydro_31 CMS3_k127_6841236_3 1122176.KB903554_gene3912 2.568e-83 287.0 COG1672@1|root,COG1672@2|Bacteria,4NR06@976|Bacteroidetes 976|Bacteroidetes L Leucine-rich repeat (LRR) protein - - - - - - - - - - - - AAA_16 CMS3_k127_6841236_2 240292.Ava_2971 9.437e-90 324.0 COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HKN5@1161|Nostocales 1117|Cyanobacteria S PFAM WD domain, G-beta repeat - - - - - - - - - - - - AAA_35,WD40 CMS3_k127_6841236_1 760192.Halhy_2916 8.958e-120 394.0 COG0123@1|root,COG0123@2|Bacteria,4NF3X@976|Bacteroidetes 976|Bacteroidetes BQ including yeast histone deacetylase and acetoin utilization protein - - - - - - - - - - - - Hist_deacetyl CMS3_k127_6841236_0 382464.ABSI01000012_gene2022 4.086e-307 965.0 COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,46S9M@74201|Verrucomicrobia,2IVIZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae CJ CoA binding domain - - - - - - - - - - - - ATP-grasp_5,CoA_binding_2,Succ_CoA_lig CMS3_k127_6841236_4 387093.SUN_0817 5.302e-25 106.0 28MAE@1|root,2ZAP3@2|Bacteria 2|Bacteria S YARHG - - - - - - - - - - - - YARHG CMS3_k127_6841392_0 867900.Celly_2987 0.0 1091.0 COG1629@1|root,COG4771@2|Bacteria,4NFJJ@976|Bacteroidetes,1HXEC@117743|Flavobacteriia,1F9VX@104264|Cellulophaga 976|Bacteroidetes P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6841392_1 1121897.AUGO01000007_gene396 9.747e-134 440.0 COG1520@1|root,COG1520@2|Bacteria,4NHPR@976|Bacteroidetes,1HXXS@117743|Flavobacteriia,2NY8D@237|Flavobacterium 976|Bacteroidetes S Arylsulfotransferase (ASST) - - - - - - - - - - - - Arylsulfotrans CMS3_k127_6847712_1 1313421.JHBV01000025_gene991 5.02e-09 59.0 2DCT2@1|root,32U08@2|Bacteria,4P1IT@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6847712_0 91464.S7335_60 5.591e-126 431.0 COG0553@1|root,COG3886@1|root,COG0553@2|Bacteria,COG3886@2|Bacteria,1FZVD@1117|Cyanobacteria,1H3XN@1129|Synechococcus 1117|Cyanobacteria L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,PLDc_2,ResIII,SNF2_N CMS3_k127_6848153_1 518766.Rmar_0090 2.216e-84 286.0 COG1842@1|root,COG1842@2|Bacteria,4P0T5@976|Bacteroidetes,1FIR5@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes KT PspA/IM30 family - - - ko:K03969 - - - - ko00000 - - - PspA_IM30 CMS3_k127_6848153_0 518766.Rmar_1216 2.286e-124 407.0 COG0158@1|root,COG0158@2|Bacteria,4NG06@976|Bacteroidetes,1FIK0@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes G D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 fbp - 3.1.3.11 ko:K03841 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910 M00003,M00165,M00167,M00344 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000,ko04147 - - - FBPase CMS3_k127_6848153_4 641524.ADICYQ_3852 9.597e-05 53.0 COG3103@1|root,COG3103@2|Bacteria,4NIH7@976|Bacteroidetes,47P4Z@768503|Cytophagia 976|Bacteroidetes T Sh3 type 3 domain protein - - - - - - - - - - - - SH3_3,SH3_4 CMS3_k127_6848153_2 686340.Metal_2120 1.417e-06 62.0 28MV6@1|root,2ZB2T@2|Bacteria,1R710@1224|Proteobacteria,1SMZR@1236|Gammaproteobacteria,1XEVI@135618|Methylococcales 135618|Methylococcales - - - - - - - - - - - - - - - CMS3_k127_684884_1 926562.Oweho_2422 1.065e-68 236.0 COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1HWZZ@117743|Flavobacteriia,2PADT@246874|Cryomorphaceae 976|Bacteroidetes S Calcineurin-like phosphoesterase lpxH - 3.6.1.54 ko:K03269 ko00540,ko01100,map00540,map01100 M00060 R04549 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Metallophos,Metallophos_2 CMS3_k127_684884_0 1279009.ADICEAN_02505 3.979e-245 773.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,47KKF@768503|Cytophagia 976|Bacteroidetes O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CMS3_k127_684884_2 925409.KI911562_gene2105 0.0001843 52.0 2DQ4P@1|root,334QK@2|Bacteria,4NVS1@976|Bacteroidetes,1IU46@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6850855_8 1286632.P278_23880 1.395e-26 109.0 COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1HYUT@117743|Flavobacteriia 976|Bacteroidetes C Nitrous oxide reductase nosZ - 1.7.2.4 ko:K00376 ko00910,ko01120,map00910,map01120 M00529 R02804 RC02861 ko00000,ko00001,ko00002,ko01000 - - - - CMS3_k127_6850855_5 1122176.KB903565_gene3239 4.609e-65 227.0 COG4314@1|root,COG4314@2|Bacteria,4NIPU@976|Bacteroidetes,1IR80@117747|Sphingobacteriia 976|Bacteroidetes C lipoprotein involved in nitrous oxide reduction - - - ko:K19342 - - - - ko00000 - - - NosL CMS3_k127_6850855_6 746697.Aeqsu_0141 1.814e-33 134.0 COG4314@1|root,COG4314@2|Bacteria,4NVVP@976|Bacteroidetes,1I2Z0@117743|Flavobacteriia 976|Bacteroidetes C NosL - - - ko:K19342 - - - - ko00000 - - - NosL CMS3_k127_6850855_1 1122176.KB903565_gene3237 2.317e-137 451.0 COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1IRBN@117747|Sphingobacteriia 976|Bacteroidetes P PFAM Periplasmic copper-binding protein (NosD) nosD - - ko:K07218 - - - - ko00000 - - - NosD CMS3_k127_6850855_4 1296416.JACB01000039_gene1337 6.961e-79 269.0 COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,1HYYD@117743|Flavobacteriia,2YIUI@290174|Aquimarina 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K19340 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC_tran CMS3_k127_6850855_3 985255.APHJ01000039_gene95 4.908e-83 283.0 COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1HXF5@117743|Flavobacteriia,2P7D6@244698|Gillisia 976|Bacteroidetes S nitrous oxide - - - ko:K19341 ko02010,map02010 M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1.132.2 - - ABC2_membrane_2,ABC2_membrane_5 CMS3_k127_6850855_10 313595.P700755_000885 1.069e-23 104.0 COG2382@1|root,COG2382@2|Bacteria,4NGBK@976|Bacteroidetes,1I15X@117743|Flavobacteriia,4C442@83612|Psychroflexus 976|Bacteroidetes P Putative esterase - - - - - - - - - - - - Esterase CMS3_k127_6850855_0 221288.JH992901_gene3895 7.982e-169 541.0 COG0715@1|root,COG0715@2|Bacteria,1GFIM@1117|Cyanobacteria 1117|Cyanobacteria P Protein of unknown function (DUF3500) - - - - - - - - - - - - DUF3500 CMS3_k127_6850855_9 926556.Echvi_3034 4.144e-24 102.0 COG4895@1|root,COG4895@2|Bacteria,4NUT0@976|Bacteroidetes,47RYA@768503|Cytophagia 976|Bacteroidetes S Uncharacterized conserved protein (DUF2196) - - - - - - - - - - - - DUF2196 CMS3_k127_6850855_7 530564.Psta_0072 2.722e-30 124.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 CMS3_k127_6850855_2 313606.M23134_06048 9.703e-123 397.0 COG0604@1|root,COG0604@2|Bacteria,4NEYW@976|Bacteroidetes,47MCY@768503|Cytophagia 976|Bacteroidetes C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2,MaoC_dehydratas CMS3_k127_6854420_2 984262.SGRA_1189 4.534e-15 79.0 COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1IPIC@117747|Sphingobacteriia 976|Bacteroidetes S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 CMS3_k127_6854420_1 153721.MYP_779 3.519e-96 335.0 COG1404@1|root,COG1404@2|Bacteria,4NEIJ@976|Bacteroidetes,47KS3@768503|Cytophagia 976|Bacteroidetes O Peptidase S8 and S53 subtilisin kexin sedolisin aprN - - - - - - - - - - - Peptidase_S8 CMS3_k127_6854420_0 1356852.N008_06525 5.235e-116 380.0 COG1760@1|root,COG1760@2|Bacteria,4NENR@976|Bacteroidetes,47JRY@768503|Cytophagia 976|Bacteroidetes E PFAM Serine dehydratase alpha chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha CMS3_k127_6854570_1 616991.JPOO01000001_gene3719 1.217e-121 399.0 COG2367@1|root,COG2367@2|Bacteria,4NHF9@976|Bacteroidetes,1HZHM@117743|Flavobacteriia,23GV7@178469|Arenibacter 976|Bacteroidetes V Beta-lactamase enzyme family - - - - - - - - - - - - Beta-lactamase2 CMS3_k127_6854570_0 1353276.JADR01000006_gene1179 6.217e-257 806.0 COG0574@1|root,COG0574@2|Bacteria,4NH4R@976|Bacteroidetes,1HWKY@117743|Flavobacteriia 976|Bacteroidetes G Pyruvate phosphate dikinase - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N CMS3_k127_6861014_1 1288963.ADIS_2438 2.959e-156 500.0 COG4299@1|root,COG4299@2|Bacteria,4NGKU@976|Bacteroidetes,47KTV@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF5009) - - - - - - - - - - - - DUF5009 CMS3_k127_6861014_0 616991.JPOO01000003_gene2405 1.557e-242 760.0 COG0520@1|root,COG0520@2|Bacteria 2|Bacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Aminotran_5,Cys_Met_Meta_PP CMS3_k127_6861014_2 1229276.DI53_1126 1.495e-19 93.0 COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,1IQAM@117747|Sphingobacteriia 976|Bacteroidetes S Amidohydrolase family - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1,Amidohydro_3 CMS3_k127_6861539_0 1313421.JHBV01000032_gene1677 1.016e-32 142.0 COG5305@1|root,COG5305@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PMT_2 CMS3_k127_6862087_1 1120965.AUBV01000003_gene469 2.021e-18 96.0 28I8D@1|root,32Q7B@2|Bacteria,4PBP6@976|Bacteroidetes,47W40@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_6862087_2 999419.HMPREF1077_00802 1.199e-14 87.0 COG2373@1|root,COG2373@2|Bacteria,4NGYZ@976|Bacteroidetes,2G2ZM@200643|Bacteroidia,230MC@171551|Porphyromonadaceae 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - - CMS3_k127_6862087_0 1121930.AQXG01000004_gene2941 1.071e-54 194.0 COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1IT31@117747|Sphingobacteriia 976|Bacteroidetes E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase CMS3_k127_6865080_2 388413.ALPR1_11290 2.1e-104 343.0 COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_6865080_0 1121904.ARBP01000002_gene6699 0.0 1364.0 COG1413@1|root,COG2133@1|root,COG3241@1|root,COG3250@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3241@2|Bacteria,COG3250@2|Bacteria,COG3828@2|Bacteria,4NFYI@976|Bacteroidetes,47JTV@768503|Cytophagia 976|Bacteroidetes CG PFAM Blue (type 1) copper domain - - - ko:K09992 - - - - ko00000 - - - Copper-bind,Laminin_G_3,ThuA CMS3_k127_6865080_1 1122605.KB893644_gene1244 2.809e-126 412.0 COG2374@1|root,COG2374@2|Bacteria,4NI8T@976|Bacteroidetes,1ISCV@117747|Sphingobacteriia 976|Bacteroidetes L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos CMS3_k127_6867884_0 1123276.KB893290_gene5275 2.22e-119 400.0 COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_6867884_1 1121931.AUHG01000017_gene1615 1.874e-33 136.0 COG0664@1|root,COG0664@2|Bacteria,4NJCE@976|Bacteroidetes,1I0GX@117743|Flavobacteriia 976|Bacteroidetes T - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - cNMP_binding CMS3_k127_6869815_0 1121904.ARBP01000005_gene4484 3.798e-200 637.0 COG2133@1|root,COG3241@1|root,COG2133@2|Bacteria,COG3241@2|Bacteria,4NEMM@976|Bacteroidetes,47KGJ@768503|Cytophagia 976|Bacteroidetes CG PFAM Blue (type 1) copper domain - - - - - - - - - - - - Copper-bind CMS3_k127_6869815_1 1121904.ARBP01000005_gene4483 6.353e-162 532.0 COG2010@1|root,COG2010@2|Bacteria,4NEJ0@976|Bacteroidetes,47NVV@768503|Cytophagia 976|Bacteroidetes C Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080,PA14 CMS3_k127_6869815_2 1267535.KB906767_gene2323 0.0002096 46.0 28J3W@1|root,2Z900@2|Bacteria,3Y47Q@57723|Acidobacteria 57723|Acidobacteria S pfam nipsnap - - - - - - - - - - - - NIPSNAP CMS3_k127_6870593_2 985255.APHJ01000018_gene3044 2.778e-13 72.0 COG0732@1|root,COG1002@1|root,COG0732@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1HYJU@117743|Flavobacteriia 976|Bacteroidetes L Restriction - - - - - - - - - - - - Eco57I,TaqI_C CMS3_k127_6870593_0 1415755.JQLV01000001_gene2348 1.058e-179 581.0 COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RMWW@1236|Gammaproteobacteria,1XHBF@135619|Oceanospirillales 135619|Oceanospirillales LV RNA-directed DNA polymerase - - 2.7.7.49 ko:K00986 - - - - ko00000,ko01000 - - - GIIM,HNH,RVT_1,RVT_N CMS3_k127_6870593_1 391587.KAOT1_02326 3.052e-71 250.0 COG2433@1|root,COG2433@2|Bacteria,4PMMU@976|Bacteroidetes,1IJV9@117743|Flavobacteriia 976|Bacteroidetes S COG3436 Transposase and inactivated derivatives - - - - - - - - - - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 CMS3_k127_6872368_1 485918.Cpin_2236 2.338e-74 255.0 COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1IPZN@117747|Sphingobacteriia 976|Bacteroidetes S TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 CMS3_k127_6872368_2 1313421.JHBV01000016_gene5582 4.011e-44 167.0 COG1595@1|root,COG1595@2|Bacteria,4NT79@976|Bacteroidetes,1IZNZ@117747|Sphingobacteriia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6872368_0 203275.BFO_0769 4.241e-194 641.0 COG0457@1|root,COG2304@1|root,COG4676@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG4676@2|Bacteria,4NGJS@976|Bacteroidetes 976|Bacteroidetes E chaperone-mediated protein folding - - - - - - - - - - - - CarbopepD_reg_2,DUF2135,Plug,VIT CMS3_k127_6872368_3 1408433.JHXV01000038_gene2218 1.295e-32 130.0 COG0438@1|root,COG0438@2|Bacteria,4NFD3@976|Bacteroidetes,1HX3M@117743|Flavobacteriia,2PBBU@246874|Cryomorphaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 CMS3_k127_6882352_0 323259.Mhun_2840 1.288e-55 221.0 COG3291@1|root,arCOG02516@1|root,arCOG03264@1|root,arCOG03606@1|root,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,arCOG03264@2157|Archaea,arCOG03606@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia 224756|Methanomicrobia S Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - CARDB,DUF3344,PKD CMS3_k127_6882352_3 1173023.KE650771_gene3059 0.0002104 55.0 COG4932@1|root,COG4932@2|Bacteria,1G7U0@1117|Cyanobacteria,1JJCX@1189|Stigonemataceae 1117|Cyanobacteria M amine dehydrogenase activity - - - - - - - - - - - - DUF11,SdrD_B CMS3_k127_6882352_2 926562.Oweho_2612 4.016e-05 57.0 COG3291@1|root,COG3291@2|Bacteria,4NI4A@976|Bacteroidetes,1I0P7@117743|Flavobacteriia,2PBKJ@246874|Cryomorphaceae 976|Bacteroidetes O PKD domain - - - - - - - - - - - - Cleaved_Adhesin,MAM,PKD,fn3 CMS3_k127_6882352_1 926562.Oweho_2395 4.117e-54 195.0 COG1595@1|root,COG1595@2|Bacteria,4NKHT@976|Bacteroidetes,1IG88@117743|Flavobacteriia,2PB14@246874|Cryomorphaceae 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6891631_5 1123248.KB893370_gene5032 1.994e-57 203.0 COG3795@1|root,COG3795@2|Bacteria,4NQPY@976|Bacteroidetes,1IYMH@117747|Sphingobacteriia 976|Bacteroidetes S YCII-related domain - - - - - - - - - - - - YCII CMS3_k127_6891631_0 1123248.KB893370_gene5031 3.772e-197 621.0 COG4941@1|root,COG4941@2|Bacteria,4NGCS@976|Bacteroidetes,1IRPG@117747|Sphingobacteriia 976|Bacteroidetes K PFAM RNA polymerase sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6891631_3 1434325.AZQN01000003_gene2366 7.257e-124 404.0 2BZ6M@1|root,2Z7HW@2|Bacteria,4NDZE@976|Bacteroidetes,47M8V@768503|Cytophagia 976|Bacteroidetes S Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_6891631_7 929556.Solca_2229 1.745e-31 132.0 COG2353@1|root,COG2353@2|Bacteria 2|Bacteria O YceI-like domain - - - - - - - - - - - - CarboxypepD_reg,YceI CMS3_k127_6891631_9 1123057.P872_21260 3.173e-17 86.0 COG2010@1|root,COG2010@2|Bacteria,4NYN7@976|Bacteroidetes 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - PSCyt1 CMS3_k127_6891631_4 1123057.P872_21265 3.183e-70 249.0 COG3637@1|root,COG3637@2|Bacteria,4NE33@976|Bacteroidetes,47UNC@768503|Cytophagia 976|Bacteroidetes M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - - - - - - - - - - - CMS3_k127_6891631_2 929556.Solca_2233 1.061e-124 406.0 COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S dicluster domain - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_11 CMS3_k127_6891631_1 866536.Belba_1302 6.172e-168 538.0 COG5557@1|root,COG5557@2|Bacteria,4NE3X@976|Bacteroidetes,47K18@768503|Cytophagia 976|Bacteroidetes C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD CMS3_k127_6891631_8 929556.Solca_2235 2.125e-31 136.0 2ECDZ@1|root,336C7@2|Bacteria,4NXCE@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6891631_6 929556.Solca_2236 9.164e-38 147.0 COG2010@1|root,COG2010@2|Bacteria,4NRFW@976|Bacteroidetes,1IU4G@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 CMS3_k127_6898158_8 468059.AUHA01000005_gene2426 2.377e-26 111.0 COG0640@1|root,COG0640@2|Bacteria,4NSAV@976|Bacteroidetes,1IT7Z@117747|Sphingobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - HTH_34 CMS3_k127_6898158_6 1122605.KB893644_gene1457 2.156e-55 200.0 COG3127@1|root,COG3127@2|Bacteria,4NN8S@976|Bacteroidetes,1IRV7@117747|Sphingobacteriia 976|Bacteroidetes Q membrane - - - - - - - - - - - - - CMS3_k127_6898158_5 1107311.Q767_01615 7.311e-75 274.0 COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium 976|Bacteroidetes G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - He_PIG,I-set,Ig_3,SBBP CMS3_k127_6898158_7 929556.Solca_2127 1.696e-42 161.0 COG2020@1|root,COG2020@2|Bacteria,4PGXX@976|Bacteroidetes,1IUNY@117747|Sphingobacteriia 976|Bacteroidetes O Phospholipid methyltransferase - - - - - - - - - - - - PEMT CMS3_k127_6898158_10 102125.Xen7305DRAFT_00022410 3.996e-16 88.0 2F5F1@1|root,33Y0S@2|Bacteria,1GE3G@1117|Cyanobacteria,3VJT1@52604|Pleurocapsales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_6898158_3 1121904.ARBP01000006_gene3725 6.013e-159 508.0 COG4447@1|root,COG4447@2|Bacteria,4NKUX@976|Bacteroidetes,47U4I@768503|Cytophagia 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - - CMS3_k127_6898158_9 1250232.JQNJ01000001_gene3440 8.748e-26 112.0 COG4319@1|root,COG4319@2|Bacteria,4PC8Z@976|Bacteroidetes,1IB5D@117743|Flavobacteriia 976|Bacteroidetes S ketosteroid isomerase - - - - - - - - - - - - DUF4440 CMS3_k127_6898158_2 643867.Ftrac_2268 2.685e-190 601.0 COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47TK8@768503|Cytophagia 976|Bacteroidetes JKL Belongs to the DEAD box helicase family rhlE - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C CMS3_k127_6898158_4 1123278.KB893428_gene102 1.11e-80 277.0 COG0491@1|root,COG0491@2|Bacteria,4NJZR@976|Bacteroidetes,47PJC@768503|Cytophagia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_6898158_1 143224.JQMD01000002_gene217 1.718e-198 629.0 COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,1HZWB@117743|Flavobacteriia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,PA14,Sulfatase CMS3_k127_6898158_0 1121904.ARBP01000011_gene1427 1.839e-241 754.0 COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,47J96@768503|Cytophagia 976|Bacteroidetes G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome CMS3_k127_6898158_11 1122225.AULQ01000009_gene304 1.43e-05 51.0 COG2373@1|root,COG2373@2|Bacteria,4PNZM@976|Bacteroidetes,1I10G@117743|Flavobacteriia 976|Bacteroidetes S Large extracellular alpha-helical protein - - - - - - - - - - - - - CMS3_k127_6905916_0 243090.RB4769 1.519e-07 55.0 28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - CMS3_k127_6913674_2 1035193.HMPREF9073_00348 3.248e-27 123.0 COG0286@1|root,COG0286@2|Bacteria,4NJ3U@976|Bacteroidetes 976|Bacteroidetes L N-6 DNA methylase - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HSDR_N_2,Methylase_S,N6_Mtase CMS3_k127_6913674_3 63737.Npun_R5747 2.65e-06 59.0 COG0457@1|root,COG1672@1|root,COG4995@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG4995@2|Bacteria,1G2QK@1117|Cyanobacteria,1HM44@1161|Nostocales 1117|Cyanobacteria LO Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - AAA_16,CHAT,TPR_12,TPR_7,TPR_8 CMS3_k127_6913674_0 1089547.KB913013_gene4041 6.395e-136 440.0 COG0535@1|root,COG0535@2|Bacteria,4NGWY@976|Bacteroidetes,47K59@768503|Cytophagia 976|Bacteroidetes C Radical SAM - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM CMS3_k127_6913674_1 1313421.JHBV01000019_gene5311 4.406e-84 290.0 COG0395@1|root,COG0395@2|Bacteria,4NIYE@976|Bacteroidetes,1IPT7@117747|Sphingobacteriia 976|Bacteroidetes G Inward rectifier potassium channel irk - - ko:K08715 - - - - ko00000,ko02000 1.A.2.2 - - IRK CMS3_k127_69154_1 1288963.ADIS_1893 4.96e-236 743.0 COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 9 - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CelD_N,Glyco_hydro_9 CMS3_k127_69154_2 1484460.JSWG01000001_gene2254 1.207e-26 119.0 COG3714@1|root,COG3714@2|Bacteria,4NMZ9@976|Bacteroidetes,1I1IJ@117743|Flavobacteriia 976|Bacteroidetes S YhhN family - - - - - - - - - - - - YhhN CMS3_k127_69154_0 1121904.ARBP01000001_gene5338 4.594e-282 883.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia 976|Bacteroidetes J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CMS3_k127_6915772_3 1484460.JSWG01000009_gene131 1.164e-18 87.0 COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,1HYXB@117743|Flavobacteriia 976|Bacteroidetes P COG0659 Sulfate permease and related - - - - - - - - - - - - Sulfate_transp CMS3_k127_6915772_1 2880.D7FW33 1.183e-55 204.0 2CY1Q@1|root,2S1CE@2759|Eukaryota 2759|Eukaryota S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE CMS3_k127_6915772_0 313603.FB2170_15971 1.151e-111 374.0 2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1I15D@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - DUF481 CMS3_k127_6915772_2 1249975.JQLP01000005_gene717 8.732e-26 110.0 COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes,1HYIW@117743|Flavobacteriia,2P5ZK@244698|Gillisia 976|Bacteroidetes T Protein tyrosine phosphatase - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - - CMS3_k127_6926485_4 471854.Dfer_2566 2.146e-100 339.0 2CD2X@1|root,2Z7RW@2|Bacteria,4NI6Q@976|Bacteroidetes,47M77@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6926485_0 761193.Runsl_0537 2.515e-306 976.0 COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NH6B@976|Bacteroidetes,47MFW@768503|Cytophagia 976|Bacteroidetes C PFAM PBS lyase - - - - - - - - - - - - Cytochrom_C,GSDH,HEAT_2 CMS3_k127_6926485_6 760192.Halhy_1640 2.315e-85 287.0 COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1IQJB@117747|Sphingobacteriia 976|Bacteroidetes S Intracellular protease, PfpI family - - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI CMS3_k127_6926485_7 391603.FBALC1_14057 3.832e-58 212.0 COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1HYN3@117743|Flavobacteriia 976|Bacteroidetes S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 CMS3_k127_6926485_3 760192.Halhy_3688 6.301e-112 368.0 COG1073@1|root,COG1073@2|Bacteria,4NGCE@976|Bacteroidetes,1IVZZ@117747|Sphingobacteriia 976|Bacteroidetes S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 CMS3_k127_6926485_1 760192.Halhy_3333 6.731e-171 554.0 COG1022@1|root,COG1022@2|Bacteria,4NEA4@976|Bacteroidetes,1IQD6@117747|Sphingobacteriia 976|Bacteroidetes I AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding CMS3_k127_6926485_2 1499967.BAYZ01000109_gene2967 2.103e-129 417.0 COG1028@1|root,COG1028@2|Bacteria,2NPDM@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_6926485_5 925409.KI911562_gene2927 1.174e-85 297.0 COG2706@1|root,COG2706@2|Bacteria,4NE87@976|Bacteroidetes,1INQI@117747|Sphingobacteriia 976|Bacteroidetes G 3-carboxymuconate cyclase - - 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase CMS3_k127_6938914_2 32057.KB217480_gene8327 8.901e-29 130.0 COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HMW7@1161|Nostocales 1117|Cyanobacteria S WD domain, G-beta repeat - - - - - - - - - - - - NB-ARC,WD40 CMS3_k127_6938914_1 143224.JQMD01000002_gene1462 4.196e-119 400.0 COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,1I0DS@117743|Flavobacteriia 976|Bacteroidetes S Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - - - - - - - - - - VCBS CMS3_k127_6938914_0 760192.Halhy_4234 1.699e-145 469.0 COG2272@1|root,COG2272@2|Bacteria,4NF5N@976|Bacteroidetes,1IRFR@117747|Sphingobacteriia 976|Bacteroidetes I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase CMS3_k127_694041_4 153721.MYP_2443 2.058e-56 205.0 COG4122@1|root,COG4122@2|Bacteria 2|Bacteria E O-methyltransferase activity - - - - - - - - - - - - Methyltransf_21,SAM_MT CMS3_k127_694041_0 153721.MYP_1440 1.694e-129 425.0 COG0128@1|root,COG0128@2|Bacteria,4NE8T@976|Bacteroidetes,47K1U@768503|Cytophagia 976|Bacteroidetes E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase CMS3_k127_694041_2 1122176.KB903531_gene2908 6.331e-82 280.0 COG0345@1|root,COG0345@2|Bacteria,4NGIG@976|Bacteroidetes,1IXBC@117747|Sphingobacteriia 976|Bacteroidetes E Pyrroline-5-carboxylate reductase dimerisation proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer CMS3_k127_694041_3 1250232.JQNJ01000001_gene1913 1.219e-80 291.0 COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia 976|Bacteroidetes Q COG1228 Imidazolonepropionase and related - - - - - - - - - - - - Amidohydro_1 CMS3_k127_694041_5 378806.STAUR_7640 1.279e-10 74.0 COG0457@1|root,COG1680@1|root,COG0457@2|Bacteria,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,4396X@68525|delta/epsilon subdivisions,2X4DR@28221|Deltaproteobacteria,2YYTQ@29|Myxococcales 28221|Deltaproteobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase,TPR_2 CMS3_k127_694041_1 1124780.ANNU01000019_gene1708 6.205e-110 364.0 COG1262@1|root,COG1262@2|Bacteria,4NF01@976|Bacteroidetes,47JJI@768503|Cytophagia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 egtB - - - - - - - - - - - DinB_2,FGE-sulfatase CMS3_k127_6941864_0 313606.M23134_07770 3.901e-156 501.0 COG0019@1|root,COG0019@2|Bacteria,4NE7X@976|Bacteroidetes,47JBT@768503|Cytophagia 976|Bacteroidetes E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CMS3_k127_6941864_2 794903.OPIT5_05425 2.123e-96 329.0 COG2334@1|root,COG2334@2|Bacteria,46TIS@74201|Verrucomicrobia 74201|Verrucomicrobia S Phosphotransferase enzyme family - - - - - - - - - - - - APH CMS3_k127_6941864_1 886379.AEWI01000040_gene2794 6.847e-107 354.0 COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,2G07F@200643|Bacteroidia,3XIYN@558415|Marinilabiliaceae 976|Bacteroidetes JM Nucleotidyl transferase - - - - - - - - - - - - NTP_transferase CMS3_k127_6942840_0 1122165.AUHS01000047_gene3184 8.899e-128 451.0 COG1520@1|root,COG1520@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales 118969|Legionellales DZ Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - DUF5122 CMS3_k127_6942840_3 521393.JH806634_gene1953 6.016e-10 74.0 COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4D412@85005|Actinomycetales 201174|Actinobacteria S the current gene model (or a revised gene model) may contain a wcoG - - - - - - - - - - - Laminin_G_3,PKD CMS3_k127_6942840_1 243090.RB1599 4.822e-87 297.0 COG1335@1|root,COG1335@2|Bacteria,2IX7K@203682|Planctomycetes 203682|Planctomycetes Q Isochorismatase family - - - - - - - - - - - - Isochorismatase,ThuA CMS3_k127_6942840_2 1048983.EL17_07490 1.532e-41 158.0 COG0577@1|root,COG0577@2|Bacteria,4PNAC@976|Bacteroidetes,47YA6@768503|Cytophagia 976|Bacteroidetes V Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_6944025_0 760192.Halhy_2347 0.0 1013.0 COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1INXI@117747|Sphingobacteriia 976|Bacteroidetes EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly icmF - 5.4.99.13 ko:K11942 - - - - ko00000,ko01000 - - - ArgK,B12-binding,MM_CoA_mutase CMS3_k127_6944025_1 761193.Runsl_3947 6.893e-140 453.0 COG0399@1|root,COG0399@2|Bacteria,4NEBI@976|Bacteroidetes,47J92@768503|Cytophagia 976|Bacteroidetes E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 CMS3_k127_6953246_1 1150864.MILUP08_42966 2.51e-20 90.0 COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4DANG@85008|Micromonosporales 201174|Actinobacteria IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) kduD1 - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 CMS3_k127_6953246_0 1122179.KB890417_gene3213 3.077e-82 289.0 2C34F@1|root,2ZA5Y@2|Bacteria,4NGPA@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_696670_0 1408473.JHXO01000002_gene3870 1.058e-93 316.0 COG1506@1|root,COG1506@2|Bacteria,4PKHC@976|Bacteroidetes 976|Bacteroidetes E Prolyl oligopeptidase family - - - - - - - - - - - - Peptidase_S9 CMS3_k127_696670_1 1279009.ADICEAN_03673 2.531e-50 181.0 COG0346@1|root,COG0346@2|Bacteria,4P4RR@976|Bacteroidetes 976|Bacteroidetes E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase CMS3_k127_696670_2 1122176.KB903569_gene3490 5.762e-15 74.0 2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1ITQ6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6973048_6 1296415.JACC01000022_gene4111 7.011e-34 149.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1HXNK@117743|Flavobacteriia,2YHT1@290174|Aquimarina 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_6973048_1 644282.Deba_2365 3.264e-118 393.0 COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM Extracellular ligand-binding receptor - - - - - - - - - - - - Peripla_BP_6 CMS3_k127_6973048_0 96561.Dole_3006 1.239e-233 737.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MHUE@213118|Desulfobacterales 28221|Deltaproteobacteria I PFAM AMP-dependent synthetase and ligase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding CMS3_k127_6973048_3 96561.Dole_3007 1.245e-101 336.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42QDN@68525|delta/epsilon subdivisions,2WKRW@28221|Deltaproteobacteria,2MMXT@213118|Desulfobacterales 28221|Deltaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS3_k127_6973048_5 644282.Deba_1709 2.744e-88 299.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42PJN@68525|delta/epsilon subdivisions,2WIPZ@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM ABC transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS3_k127_6973048_4 644282.Deba_1711 1.891e-97 327.0 COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,42NUW@68525|delta/epsilon subdivisions,2WMC0@28221|Deltaproteobacteria 28221|Deltaproteobacteria U PFAM Branched-chain amino acid transport system permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS3_k127_6973048_2 644282.Deba_1712 2.967e-109 364.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42MTH@68525|delta/epsilon subdivisions,2WJQY@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM Branched-chain amino acid transport system permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS3_k127_6973048_8 709991.Odosp_1317 1.971e-10 70.0 2BZEB@1|root,2ZMZD@2|Bacteria,4NMWK@976|Bacteroidetes,2FQNP@200643|Bacteroidia,22XQ3@171551|Porphyromonadaceae 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 CMS3_k127_6973048_9 1121481.AUAS01000004_gene1553 3.777e-07 59.0 COG3047@1|root,COG3047@2|Bacteria,4NSNH@976|Bacteroidetes,47R79@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 CMS3_k127_6973604_4 1121904.ARBP01000006_gene3863 3.812e-79 280.0 COG0811@1|root,COG0811@2|Bacteria,4NRG8@976|Bacteroidetes,47P2Q@768503|Cytophagia 976|Bacteroidetes U peptide transport - - - - - - - - - - - - - CMS3_k127_6973604_3 1121904.ARBP01000006_gene3864 1.501e-79 273.0 COG1360@1|root,COG1360@2|Bacteria,4NN97@976|Bacteroidetes,47QKF@768503|Cytophagia 976|Bacteroidetes N Flagellar Motor Protein - - - - - - - - - - - - OmpA CMS3_k127_6973604_0 1237149.C900_00838 9.769e-200 651.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47U5S@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6973604_6 391603.FBALC1_02027 6.11e-29 119.0 COG1695@1|root,COG1695@2|Bacteria,4NUDG@976|Bacteroidetes 976|Bacteroidetes K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR CMS3_k127_6973604_1 1288963.ADIS_3259 1.96e-182 591.0 COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,4NI4S@976|Bacteroidetes,47M53@768503|Cytophagia 976|Bacteroidetes CL Protein of unknown function (DUF1595) - - - - - - - - - - - - PSCyt3,PSD2,PSD3,PSD4,PSD5 CMS3_k127_6973604_2 1288963.ADIS_3260 2.581e-179 572.0 COG2960@1|root,COG2960@2|Bacteria,4NFIK@976|Bacteroidetes,47N49@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1552) - - - - - - - - - - - - HXXSHH CMS3_k127_6973604_5 1121904.ARBP01000014_gene136 2.432e-72 258.0 COG4244@1|root,COG4886@1|root,COG4244@2|Bacteria,COG4886@2|Bacteria,4NK9B@976|Bacteroidetes,47MQB@768503|Cytophagia 976|Bacteroidetes S Planctomycete cytochrome C - - - - - - - - - - - - PSCyt1 CMS3_k127_6981420_1 153721.MYP_1127 1.308e-145 470.0 COG0436@1|root,COG0436@2|Bacteria,4NES3@976|Bacteroidetes,47MBR@768503|Cytophagia 976|Bacteroidetes E PFAM Aminotransferase class I and II ybdL - 2.6.1.88 ko:K14287 - - R08618 RC00006,RC00025 ko00000,ko01000,ko01007 - - - Aminotran_1_2 CMS3_k127_6981420_3 489825.LYNGBM3L_39350 6.255e-14 85.0 COG0419@1|root,COG0457@1|root,COG0419@2|Bacteria,COG0457@2|Bacteria,1G1U5@1117|Cyanobacteria,1H8FU@1150|Oscillatoriales 1117|Cyanobacteria L Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 CMS3_k127_6981420_0 762903.Pedsa_1912 7.057e-239 759.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,1INSH@117747|Sphingobacteriia 976|Bacteroidetes J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 CMS3_k127_6981420_2 1121904.ARBP01000010_gene2381 4.741e-27 114.0 COG0204@1|root,COG0204@2|Bacteria,4NF25@976|Bacteroidetes,47NUX@768503|Cytophagia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acetyltransf_5,Acyltransferase CMS3_k127_6984299_5 1443665.JACA01000019_gene4825 5.164e-88 299.0 2CEN7@1|root,2Z9XA@2|Bacteria,4NFTE@976|Bacteroidetes,1I7QE@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6984299_6 391596.PBAL39_05898 9.644e-83 276.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,4NFQP@976|Bacteroidetes,1J0CG@117747|Sphingobacteriia 976|Bacteroidetes C peptide methionine sulfoxide reductase - - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR CMS3_k127_6984299_11 1239962.C943_00755 6.623e-33 130.0 COG2361@1|root,COG2361@2|Bacteria,4NV8D@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 CMS3_k127_6984299_3 1122179.KB890431_gene4204 1.074e-104 352.0 COG0104@1|root,COG0104@2|Bacteria,4NN4I@976|Bacteroidetes,1IX0X@117747|Sphingobacteriia 976|Bacteroidetes F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP - - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt CMS3_k127_6984299_2 760192.Halhy_3367 4.109e-119 389.0 2BVU5@1|root,2Z9FH@2|Bacteria,4NGKS@976|Bacteroidetes,1IVF7@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6984299_7 760192.Halhy_3368 1.865e-77 268.0 COG0515@1|root,COG0515@2|Bacteria,4NQ0G@976|Bacteroidetes,1IXM4@117747|Sphingobacteriia 976|Bacteroidetes KLT serine threonine protein kinase - - - - - - - - - - - - - CMS3_k127_6984299_9 929703.KE386491_gene4219 1.165e-54 199.0 2A087@1|root,30NBF@2|Bacteria,4NMD0@976|Bacteroidetes,47P70@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_6984299_4 886293.Sinac_2603 5.95e-100 334.0 COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes 203682|Planctomycetes S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L CMS3_k127_6984299_0 641524.ADICYQ_2865 4.271e-131 429.0 COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,47U4H@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_6984299_8 886293.Sinac_0966 3.215e-77 264.0 COG3571@1|root,COG3571@2|Bacteria 2|Bacteria S histone H4-K16 acetylation - - - ko:K07020 - - - - ko00000 - - - Abhydrolase_6,DLH CMS3_k127_6984299_10 272134.KB731324_gene3650 3.583e-38 155.0 COG0500@1|root,COG2226@2|Bacteria,1GCUU@1117|Cyanobacteria,1HEQW@1150|Oscillatoriales 1117|Cyanobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 CMS3_k127_6984299_1 471223.GWCH70_0811 1.061e-125 415.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1WH62@129337|Geobacillus 91061|Bacilli E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase - - 1.4.1.2,1.4.1.4 ko:K00260,ko:K00262 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N CMS3_k127_6988653_0 865937.Gilli_2352 1.774e-118 385.0 COG1373@1|root,COG1373@2|Bacteria,4NHQG@976|Bacteroidetes,1I2E3@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_6988653_2 861299.J421_5899 7.375e-10 66.0 COG0457@1|root,COG0823@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG5616@2|Bacteria 2|Bacteria S cAMP biosynthetic process - - 2.7.11.1 ko:K03641,ko:K08282,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02000 2.C.1.2 - - DUF4214,Pkinase,SBBP,TPR_16,TPR_19,TPR_2,TPR_8 CMS3_k127_6988653_1 143224.JQMD01000002_gene2496 4.655e-56 203.0 COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_6990418_0 760192.Halhy_2051 0.0 1333.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria 2|Bacteria T PhoQ Sensor - - 4.6.1.1 ko:K01768,ko:K16923,ko:K19694 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00582,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 3.A.1.28 - - 7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_6990418_1 1121904.ARBP01000005_gene4592 1.482e-274 861.0 COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,47KDI@768503|Cytophagia 976|Bacteroidetes G Pyrrolo-quinoline quinone - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - Cytochrome_CBB3,PQQ,PQQ_2 CMS3_k127_6994163_0 1121904.ARBP01000026_gene625 1.471e-88 304.0 COG2114@1|root,COG2114@2|Bacteria,4NG5A@976|Bacteroidetes,47QPA@768503|Cytophagia 976|Bacteroidetes T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - Guanylate_cyc CMS3_k127_6994163_2 313606.M23134_05888 1.391e-45 169.0 COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,47S1F@768503|Cytophagia 976|Bacteroidetes S Glyoxalase-like domain - - - ko:K06996 - - - - ko00000 - - - Glyoxalase CMS3_k127_6994163_1 1408433.JHXV01000026_gene3066 8.933e-66 231.0 COG5587@1|root,COG5587@2|Bacteria,4NRNM@976|Bacteroidetes,1I8TV@117743|Flavobacteriia,2PATJ@246874|Cryomorphaceae 976|Bacteroidetes S Conserved hypothetical protein (DUF2461) - - - - - - - - - - - - DUF2461 CMS3_k127_6994163_8 1434325.AZQN01000008_gene3018 6.467e-10 66.0 2DM6B@1|root,31WK9@2|Bacteria,4NQK1@976|Bacteroidetes,47QS1@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF4199) - - - - - - - - - - - - DUF4199 CMS3_k127_6994163_5 1189612.A33Q_4219 1.485e-16 86.0 2CC1H@1|root,33P9C@2|Bacteria,4NYJE@976|Bacteroidetes,47RW7@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 CMS3_k127_6994163_4 1237149.C900_02644 2.297e-31 129.0 2CC1H@1|root,33P9C@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4252) - - - - - - - - - - - - DUF4252 CMS3_k127_6994163_7 391598.FBBAL38_01030 1.011e-12 74.0 COG1413@1|root,COG1413@2|Bacteria,4NUQJ@976|Bacteroidetes,1I52N@117743|Flavobacteriia 976|Bacteroidetes C lyase activity - - - - - - - - - - - - - CMS3_k127_6994163_3 1121904.ARBP01000001_gene5806 2.632e-42 161.0 COG1595@1|root,COG1595@2|Bacteria,4NMJ7@976|Bacteroidetes,47PC1@768503|Cytophagia 976|Bacteroidetes K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_6994163_6 1270193.JARP01000006_gene1680 3.392e-16 84.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,1HWYV@117743|Flavobacteriia,2NSFC@237|Flavobacterium 976|Bacteroidetes P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_6996324_1 1434325.AZQN01000007_gene3154 4.568e-67 240.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug CMS3_k127_6996324_2 1121904.ARBP01000001_gene5735 5.28e-63 226.0 COG0385@1|root,COG0385@2|Bacteria,4NFWK@976|Bacteroidetes 976|Bacteroidetes S Sodium bile acid symporter family protein - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF CMS3_k127_6996324_0 234267.Acid_2070 1.781e-162 521.0 COG0366@1|root,COG0366@2|Bacteria,3Y6H6@57723|Acidobacteria 57723|Acidobacteria G Alpha amylase, catalytic domain - - 2.4.1.7,3.2.1.1,5.4.99.16 ko:K00690,ko:K05343 ko00500,ko01100,map00500,map01100 - R00803,R01557,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C CMS3_k127_6996502_1 1121904.ARBP01000008_gene3254 4.778e-237 738.0 COG3119@1|root,COG3119@2|Bacteria,4NFC9@976|Bacteroidetes,47KWC@768503|Cytophagia 976|Bacteroidetes P Domain of unknown function - - - - - - - - - - - - DUF4994,Sulfatase CMS3_k127_6996502_5 1380384.JADN01000008_gene1202 1.576e-110 365.0 COG2335@1|root,COG2335@2|Bacteria,4NH49@976|Bacteroidetes,1HXZS@117743|Flavobacteriia 976|Bacteroidetes M Secreted and surface protein containing fasciclin-like repeats - - - - - - - - - - - - Fasciclin CMS3_k127_6996502_0 1122226.AUHX01000001_gene633 0.0 1121.0 COG2838@1|root,COG2838@2|Bacteria,4NFV1@976|Bacteroidetes,1HXKQ@117743|Flavobacteriia 976|Bacteroidetes C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - IDH CMS3_k127_6996502_6 1121481.AUAS01000009_gene102 1.046e-98 355.0 COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes,47Y2E@768503|Cytophagia 976|Bacteroidetes T Two component regulator three Y domain protein - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_6996502_3 1408473.JHXO01000010_gene3699 4.114e-126 414.0 COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes,2FPA0@200643|Bacteroidia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP CMS3_k127_6996502_2 926562.Oweho_3326 1.243e-128 423.0 COG0577@1|root,COG0577@2|Bacteria,4NFUG@976|Bacteroidetes,1HZ09@117743|Flavobacteriia 976|Bacteroidetes V ABC-type antimicrobial peptide transport system, permease component macB_3 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6996502_4 1313421.JHBV01000007_gene4261 2.507e-125 414.0 COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IQQ0@117747|Sphingobacteriia 976|Bacteroidetes V COG0577 ABC-type antimicrobial peptide transport system permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_6996502_7 1168034.FH5T_10690 1.677e-67 231.0 COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,2FNRG@200643|Bacteroidia 976|Bacteroidetes V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_7000904_1 1122176.KB903571_gene4785 1.136e-107 384.0 COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1IP6G@117747|Sphingobacteriia 976|Bacteroidetes G PFAM glycoside hydrolase family 3 - - - - - - - - - - - - Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_7000904_0 760192.Halhy_1664 3.379e-157 517.0 2EZ48@1|root,30K0H@2|Bacteria,4P965@976|Bacteroidetes,1IZT0@117747|Sphingobacteriia 760192.Halhy_1664|- S IMG reference gene - - - - - - - - - - - - - CMS3_k127_7002164_2 1408813.AYMG01000010_gene457 8.954e-20 95.0 28JE3@1|root,2Z98B@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - AbiEii CMS3_k127_7002164_0 1313421.JHBV01000049_gene80 4.471e-58 206.0 COG1670@1|root,COG1670@2|Bacteria,4NNXN@976|Bacteroidetes 976|Bacteroidetes J (GNAT) family - - - - - - - - - - - - Acetyltransf_3 CMS3_k127_7002164_1 880070.Cycma_2756 6.113e-26 109.0 2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - Collagen_bind_2 CMS3_k127_7006553_5 613026.HRAG_00507 1.899e-85 305.0 COG2194@1|root,COG2194@2|Bacteria,1PG91@1224|Proteobacteria,42Z8J@68525|delta/epsilon subdivisions,2YR6T@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_7006553_4 1227739.Hsw_0520 4.005e-107 384.0 COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia 976|Bacteroidetes T Two component regulator propeller - - - - - - - - - - - - HATPase_c,HisKA_3,Reg_prop,Y_Y_Y CMS3_k127_7006553_7 1121904.ARBP01000005_gene4760 8.026e-57 206.0 COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47PWE@768503|Cytophagia 976|Bacteroidetes KT Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg CMS3_k127_7006553_0 1392498.JQLH01000001_gene3635 1.298e-157 511.0 COG0471@1|root,COG0471@2|Bacteria,4NFDK@976|Bacteroidetes,1HX3U@117743|Flavobacteriia,2PIED@252356|Maribacter 976|Bacteroidetes P Sodium:sulfate symporter transmembrane region - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp CMS3_k127_7006553_12 313606.M23134_03740 2.161e-29 120.0 COG1694@1|root,COG1694@2|Bacteria,4NX1K@976|Bacteroidetes,47SM1@768503|Cytophagia 976|Bacteroidetes S MazG nucleotide pyrophosphohydrolase domain - - - - - - - - - - - - MazG CMS3_k127_7006553_9 1255043.TVNIR_1227 1.479e-47 177.0 COG1376@1|root,COG1376@2|Bacteria,1MYZT@1224|Proteobacteria,1S8PS@1236|Gammaproteobacteria,1WY8E@135613|Chromatiales 135613|Chromatiales S ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD CMS3_k127_7006553_6 742726.HMPREF9448_00937 4.311e-69 239.0 COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes,2FMS7@200643|Bacteroidia,22WJC@171551|Porphyromonadaceae 976|Bacteroidetes L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII CMS3_k127_7006553_1 926550.CLDAP_08980 4.203e-150 484.0 COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B CMS3_k127_7006553_10 1487921.DP68_07295 3.997e-45 168.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,36JKF@31979|Clostridiaceae 186801|Clostridia L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N CMS3_k127_7006553_2 323261.Noc_2224 7.097e-116 380.0 COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1WYC9@135613|Chromatiales 135613|Chromatiales S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 CMS3_k127_7006553_11 1237149.C900_02828 1.085e-36 144.0 COG0806@1|root,COG0806@2|Bacteria,4NQF0@976|Bacteroidetes,47QUB@768503|Cytophagia 976|Bacteroidetes J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM CMS3_k127_7006553_13 1123008.KB905705_gene947 1.012e-26 119.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,22XNN@171551|Porphyromonadaceae 976|Bacteroidetes J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 CMS3_k127_7006553_3 504472.Slin_1394 8.668e-115 379.0 COG0009@1|root,COG0009@2|Bacteria,4NF5U@976|Bacteroidetes,47KX9@768503|Cytophagia 976|Bacteroidetes J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine sua5 - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC CMS3_k127_7006553_8 1308866.J416_12442 9.426e-51 183.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,47002@74385|Gracilibacillus 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A CMS3_k127_7007675_1 1121904.ARBP01000015_gene173 6.866e-171 546.0 COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_7007675_0 1408473.JHXO01000001_gene2164 1.472e-211 681.0 COG0557@1|root,COG0557@2|Bacteria,4NE7T@976|Bacteroidetes,2FMM6@200643|Bacteroidia 976|Bacteroidetes J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573,ko:K12585 ko03018,map03018 M00391 - - ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 CMS3_k127_7007675_2 1122176.KB903538_gene1548 1.866e-125 407.0 COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1IP70@117747|Sphingobacteriia 976|Bacteroidetes I 3-hydroxyacyl-CoA dehydrogenase hbd - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N CMS3_k127_7007675_3 1121904.ARBP01000002_gene7211 6.049e-117 385.0 COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia 976|Bacteroidetes E PFAM peptidase T2 asparaginase 2 - - 3.4.19.5 ko:K13051 - - - - ko00000,ko01000,ko01002 - - - Asparaginase_2 CMS3_k127_7007675_4 1042209.HK44_005020 2.497e-64 229.0 COG2173@1|root,COG3786@1|root,COG2173@2|Bacteria,COG3786@2|Bacteria,1RENK@1224|Proteobacteria,1S3SJ@1236|Gammaproteobacteria,1YR3J@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide ddpX GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 CMS3_k127_7009368_1 1168289.AJKI01000024_gene1483 2.367e-212 668.0 COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,2G221@200643|Bacteroidia,3XKUG@558415|Marinilabiliaceae 976|Bacteroidetes C Aldehyde dehydrogenase family - - 1.2.1.32,1.2.1.85 ko:K10217 ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220 M00038,M00569 R02762,R03889,R05353 RC00218,RC00254 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS3_k127_7009368_2 1313421.JHBV01000023_gene5160 5.185e-206 654.0 COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,1IZ8B@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K03307,ko:K14387 ko04725,ko05231,map04725,map05231 - - - ko00000,ko00001,ko02000 2.A.21,2.A.21.8 - - HD_4,SSF CMS3_k127_7009368_0 471854.Dfer_4840 1.83e-231 741.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7017513_1 1045009.AFXQ01000036_gene1111 4.618e-07 53.0 COG0265@1|root,COG0265@2|Bacteria,2ICC4@201174|Actinobacteria 201174|Actinobacteria O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - - - - - - - - - - - CMS3_k127_7017513_0 1122176.KB903557_gene4025 3.691e-68 258.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,1J07D@117747|Sphingobacteriia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_8 CMS3_k127_7036445_2 1191523.MROS_0837 5.534e-52 195.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family Z012_00180 - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL,Lipase_GDSL_2 CMS3_k127_7036445_6 679937.Bcop_1077 0.0008372 50.0 2BW0J@1|root,2ZUAT@2|Bacteria,4P947@976|Bacteroidetes,2FNH3@200643|Bacteroidia,4AM7U@815|Bacteroidaceae 976|Bacteroidetes S COG NOG28799 non supervised orthologous group - - - - - - - - - - - - DUF4943 CMS3_k127_7036445_4 1410613.JNKF01000010_gene637 4.351e-38 149.0 COG0703@1|root,COG0703@2|Bacteria,4NQ73@976|Bacteroidetes,2FM3K@200643|Bacteroidia 976|Bacteroidetes F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI CMS3_k127_7036445_1 1122176.KB903535_gene2005 5.081e-156 503.0 COG3540@1|root,COG3540@2|Bacteria,4NDUS@976|Bacteroidetes 976|Bacteroidetes P COG3540 Phosphodiesterase alkaline phosphatase D - - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD CMS3_k127_7036445_5 1123278.KB893403_gene3373 1.436e-34 136.0 COG1396@1|root,COG1396@2|Bacteria,4NRWV@976|Bacteroidetes,47RY8@768503|Cytophagia 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 CMS3_k127_7036445_0 1392498.JQLH01000001_gene3341 2.774e-189 599.0 COG3550@1|root,COG3550@2|Bacteria,4NFYY@976|Bacteroidetes,1HXAI@117743|Flavobacteriia 976|Bacteroidetes S Pfam:HipA_N - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C CMS3_k127_7036445_3 1121875.KB907553_gene24 1.634e-46 186.0 COG0412@1|root,COG1262@1|root,COG2114@1|root,COG0412@2|Bacteria,COG1262@2|Bacteria,COG2114@2|Bacteria,4PPKM@976|Bacteroidetes 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc CMS3_k127_7037587_1 313595.P700755_002883 1.392e-56 206.0 COG1183@1|root,COG1183@2|Bacteria,4NNUZ@976|Bacteroidetes,1HZ4M@117743|Flavobacteriia,4C2D5@83612|Psychroflexus 976|Bacteroidetes I CDP-alcohol phosphatidyltransferase pssA - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf CMS3_k127_7037587_0 1313301.AUGC01000007_gene572 1.07e-69 241.0 COG1057@1|root,COG1057@2|Bacteria,4NFQI@976|Bacteroidetes 976|Bacteroidetes H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CMS3_k127_7037587_2 1408473.JHXO01000004_gene248 1.401e-56 203.0 COG0194@1|root,COG0194@2|Bacteria,4NEDG@976|Bacteroidetes,2FNWA@200643|Bacteroidia 976|Bacteroidetes F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin CMS3_k127_7037587_3 1121011.AUCB01000005_gene2360 1.341e-33 136.0 COG2890@1|root,COG2890@2|Bacteria,4PKK6@976|Bacteroidetes,1IJBI@117743|Flavobacteriia,23FMU@178469|Arenibacter 976|Bacteroidetes J Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 CMS3_k127_7042132_5 1380600.AUYN01000003_gene162 4.109e-06 53.0 COG4929@1|root,COG4929@2|Bacteria,4NQB4@976|Bacteroidetes,1I3Q6@117743|Flavobacteriia 976|Bacteroidetes S GDYXXLXY protein - - - - - - - - - - - - GDYXXLXY CMS3_k127_7042132_0 1177181.T9A_00024 3.581e-106 355.0 COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria,1XJKP@135619|Oceanospirillales 135619|Oceanospirillales G Gluconolactonase - - - - - - - - - - - - Str_synth CMS3_k127_7042132_3 867900.Celly_0184 1.544e-20 104.0 COG3595@1|root,COG3595@2|Bacteria,4NEUW@976|Bacteroidetes,1HYD6@117743|Flavobacteriia,1F85W@104264|Cellulophaga 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7042132_2 313606.M23134_04372 7.547e-58 206.0 COG1595@1|root,COG1595@2|Bacteria,4NMAK@976|Bacteroidetes,47P7T@768503|Cytophagia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_7042132_4 313606.M23134_01994 3.119e-20 100.0 COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,47R8S@768503|Cytophagia 976|Bacteroidetes S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_7042132_1 760192.Halhy_0422 1.337e-92 313.0 COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1IP8I@117747|Sphingobacteriia 976|Bacteroidetes G PFAM Glycoside hydrolase, family 37 - - 3.2.1.28 ko:K01194 ko00500,ko01100,map00500,map01100 - R00010 RC00049 ko00000,ko00001,ko00537,ko01000 - GH37 - Trehalase CMS3_k127_704771_1 518766.Rmar_1251 3.49e-109 370.0 COG1007@1|root,COG1007@2|Bacteria,4NF94@976|Bacteroidetes,1FJ04@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M CMS3_k127_704771_4 643867.Ftrac_0272 6.355e-37 147.0 COG1309@1|root,COG1309@2|Bacteria,4NMN2@976|Bacteroidetes,47XSQ@768503|Cytophagia 976|Bacteroidetes K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_4,TetR_C_5,TetR_N CMS3_k127_704771_5 153721.MYP_2836 2.895e-05 55.0 COG1196@1|root,COG1196@2|Bacteria,4NHAC@976|Bacteroidetes,47MGD@768503|Cytophagia 976|Bacteroidetes D nuclear chromosome segregation - - - ko:K09892 - - - - ko00000,ko03036 - - - - CMS3_k127_704771_3 1122915.AUGY01000082_gene6404 9.008e-40 154.0 COG0740@1|root,COG0740@2|Bacteria,1VXMY@1239|Firmicutes 1239|Firmicutes OU Clp protease - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease CMS3_k127_704771_2 1120966.AUBU01000002_gene1962 1.197e-94 321.0 2DBNR@1|root,2ZA54@2|Bacteria,4NHW9@976|Bacteroidetes,47Y9I@768503|Cytophagia 976|Bacteroidetes S Methane oxygenase PmoA - - - - - - - - - - - - PmoA CMS3_k127_704771_0 700598.Niako_0563 2.015e-134 436.0 COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,1IRAJ@117747|Sphingobacteriia 976|Bacteroidetes G BNR repeat-like domain - - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2 CMS3_k127_704848_0 313606.M23134_04979 7.772e-260 822.0 COG0653@1|root,COG0653@2|Bacteria,4P0D7@976|Bacteroidetes,47U91@768503|Cytophagia 976|Bacteroidetes U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane - - - - - - - - - - - - SecA_DEAD,SecA_PP_bind,SecA_SW CMS3_k127_704848_1 760192.Halhy_5814 8.772e-127 426.0 COG0497@1|root,COG1672@1|root,COG0497@2|Bacteria,COG1672@2|Bacteria 2|Bacteria L DNA recombination recN - - ko:K03631,ko:K06921,ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko02000,ko03400 3.A.1.112,8.A.1 - - SMC_N,YkyA CMS3_k127_7062_0 760192.Halhy_1587 9.729e-148 481.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_7062_1 391596.PBAL39_08681 4.601e-124 424.0 COG2304@1|root,COG2304@2|Bacteria,4NKB6@976|Bacteroidetes,1IQFS@117747|Sphingobacteriia 976|Bacteroidetes S Vault protein inter-alpha-trypsin domain - - - - - - - - - - - - VIT CMS3_k127_7073620_0 1121859.KB890739_gene2762 3.369e-183 584.0 COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47M69@768503|Cytophagia 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_7073620_1 1288963.ADIS_3405 1.25e-81 280.0 COG3419@1|root,COG3419@2|Bacteria,4NGV9@976|Bacteroidetes,47MMR@768503|Cytophagia 976|Bacteroidetes NU Tfp pilus assembly protein tip-associated adhesin - - - - - - - - - - - - PQQ,PQQ_2 CMS3_k127_7079055_1 1121011.AUCB01000042_gene789 3.956e-98 325.0 COG2755@1|root,COG2755@2|Bacteria,4P281@976|Bacteroidetes,1I7CB@117743|Flavobacteriia 976|Bacteroidetes E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 CMS3_k127_7079055_4 744872.Spica_0564 3.232e-36 141.0 COG1487@1|root,COG1487@2|Bacteria,2JAUP@203691|Spirochaetes 203691|Spirochaetes S PIN domain - - - ko:K18828 - - - - ko00000,ko01000,ko02048,ko03016 - - - PIN CMS3_k127_7079055_6 1121904.ARBP01000003_gene6331 8.44e-11 71.0 COG0457@1|root,COG2114@1|root,COG2207@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG2207@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,47N72@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_7079055_3 113355.CM001775_gene2043 4.36e-58 209.0 COG4636@1|root,COG4636@2|Bacteria,1FZYR@1117|Cyanobacteria 1117|Cyanobacteria S protein conserved in cyanobacteria - - - - - - - - - - - - Uma2 CMS3_k127_7079055_9 395961.Cyan7425_2749 1.741e-06 53.0 2B8AH@1|root,321J4@2|Bacteria,1GMJZ@1117|Cyanobacteria,3KKHC@43988|Cyanothece 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_7079055_7 870187.Thini_1483 1.166e-07 54.0 2DPT8@1|root,333A5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_7079055_0 760192.Halhy_2477 1.107e-183 586.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_7079055_8 1280681.AUJZ01000021_gene3665 8.634e-07 55.0 COG1672@1|root,COG1672@2|Bacteria,1V0ZC@1239|Firmicutes,249RA@186801|Clostridia,4BWSY@830|Butyrivibrio 186801|Clostridia S PFAM Archaeal ATPase - - - - - - - - - - - - AAA_14,ATPase_2 CMS3_k127_7079055_2 761193.Runsl_4225 8.77e-62 218.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia 976|Bacteroidetes EU Dipeptidyl peptidase IV (DPP IV) N-terminal region - - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 CMS3_k127_7082639_0 760192.Halhy_2973 3.714e-140 452.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_7082639_2 760192.Halhy_5422 3.132e-17 88.0 2DZK1@1|root,32VCS@2|Bacteria,4NTZ5@976|Bacteroidetes,1ITPD@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7082639_3 1122176.KB903532_gene2492 3.588e-05 48.0 2DZK1@1|root,32VCS@2|Bacteria,4NTZ5@976|Bacteroidetes,1ITPD@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7082639_1 760192.Halhy_5421 1.909e-29 124.0 297Z5@1|root,2ZV5A@2|Bacteria,4NPFS@976|Bacteroidetes,1IUP6@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7086208_1 1408433.JHXV01000011_gene2094 3.608e-59 209.0 COG0743@1|root,COG0743@2|Bacteria,4NG0S@976|Bacteroidetes,1ICNW@117743|Flavobacteriia,2PBDY@246874|Cryomorphaceae 976|Bacteroidetes I 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom CMS3_k127_7086208_0 1227739.Hsw_1775 1.763e-261 817.0 COG3387@1|root,COG3387@2|Bacteria,4NEE6@976|Bacteroidetes,47MRU@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolases family 15 - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glyco_hydro_15 CMS3_k127_7086208_2 1313301.AUGC01000011_gene1148 1.374e-23 107.0 COG3118@1|root,COG3118@2|Bacteria,4NR34@976|Bacteroidetes 976|Bacteroidetes O PFAM thioredoxin domain - - - ko:K05838 - - - - ko00000,ko03110 - - - TPR_20,Thioredoxin CMS3_k127_7087337_1 1185876.BN8_02272 8.712e-105 348.0 COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,47K76@768503|Cytophagia 976|Bacteroidetes S Heparinase II/III-like protein - - - - - - - - - - - - DUF4962,Hepar_II_III CMS3_k127_7087337_2 1449126.JQKL01000016_gene2859 4.27e-78 271.0 COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia 186801|Clostridia I Hydrolase, alpha beta domain protein - - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 CMS3_k127_7087337_0 313606.M23134_05991 1.173e-124 413.0 COG0534@1|root,COG0534@2|Bacteria,4NG7Q@976|Bacteroidetes,47U29@768503|Cytophagia 976|Bacteroidetes V MatE dinF - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE CMS3_k127_7087337_3 1158614.I592_01444 1.174e-12 75.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,4AZFD@81852|Enterococcaceae 91061|Bacilli L RQC - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind CMS3_k127_7098592_2 984262.SGRA_0182 1.105e-67 265.0 COG3291@1|root,COG3291@2|Bacteria,4NDU9@976|Bacteroidetes 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,PKD CMS3_k127_7098592_4 700598.Niako_5475 1.118e-21 97.0 COG0721@1|root,COG0721@2|Bacteria,4NV0A@976|Bacteroidetes,1ITUB@117747|Sphingobacteriia 976|Bacteroidetes J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln CMS3_k127_7098592_6 1185876.BN8_06313 3.167e-17 97.0 COG0457@1|root,COG0457@2|Bacteria,4NGQ7@976|Bacteroidetes,47KHQ@768503|Cytophagia 976|Bacteroidetes U Tetratricopeptide repeat - - - - - - - - - - - - TPR_2,TPR_8 CMS3_k127_7098592_0 1121904.ARBP01000001_gene5663 2.425e-214 687.0 COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,47NX3@768503|Cytophagia 976|Bacteroidetes P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N CMS3_k127_7098592_5 880071.Fleli_3286 5.462e-19 92.0 COG3937@1|root,COG3937@2|Bacteria,4NUSK@976|Bacteroidetes,47SH5@768503|Cytophagia 976|Bacteroidetes S granule-associated protein - - - - - - - - - - - - - CMS3_k127_7098592_1 1121875.KB907546_gene2514 2.572e-90 303.0 COG1028@1|root,COG1028@2|Bacteria,4NGZI@976|Bacteroidetes,1I2A7@117743|Flavobacteriia 976|Bacteroidetes IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS3_k127_7098592_3 1408433.JHXV01000002_gene453 9.019e-29 117.0 COG0463@1|root,COG0463@2|Bacteria,4PM7S@976|Bacteroidetes,1IMR6@117743|Flavobacteriia,2PC6M@246874|Cryomorphaceae 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_7100252_1 761193.Runsl_0428 2.513e-217 682.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,47MNP@768503|Cytophagia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_7100252_5 742725.HMPREF9450_01687 3.205e-52 187.0 COG2166@1|root,COG2166@2|Bacteria,4NM9N@976|Bacteroidetes,2FSRV@200643|Bacteroidia,22UGD@171550|Rikenellaceae 976|Bacteroidetes S Fe-S metabolism associated domain sufE - - ko:K02426 - - - - ko00000 - - - SufE CMS3_k127_7100252_3 1131812.JQMS01000001_gene2922 5.977e-85 293.0 COG1835@1|root,COG1835@2|Bacteria,4NPI2@976|Bacteroidetes,1IMIW@117743|Flavobacteriia,2P0FR@237|Flavobacterium 976|Bacteroidetes I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 CMS3_k127_7100252_6 1392488.JHZY01000002_gene1019 3.819e-36 149.0 2EI44@1|root,33BVH@2|Bacteria,4NZCQ@976|Bacteroidetes,1I697@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7100252_4 1237149.C900_03669 2.14e-52 190.0 COG4636@1|root,COG4636@2|Bacteria,4NQFH@976|Bacteroidetes,47V8I@768503|Cytophagia 976|Bacteroidetes S Putative restriction endonuclease - - - - - - - - - - - - Uma2 CMS3_k127_7100252_0 760192.Halhy_5276 1.276e-232 745.0 COG3934@1|root,COG3934@2|Bacteria,4NJJS@976|Bacteroidetes 976|Bacteroidetes G Pkd domain containing protein - - - - - - - - - - - - Cellulase,DUF5060 CMS3_k127_7100252_2 1237149.C900_01849 1.764e-87 296.0 COG1230@1|root,COG1230@2|Bacteria,4NIHB@976|Bacteroidetes,47NNT@768503|Cytophagia 976|Bacteroidetes P Cation efflux family - - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux CMS3_k127_7100333_1 1168034.FH5T_20495 2.341e-181 577.0 COG0187@1|root,COG0187@2|Bacteria,4NE0P@976|Bacteroidetes,2FPG7@200643|Bacteroidia 976|Bacteroidetes L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CMS3_k127_7100333_2 926549.KI421517_gene1555 2.666e-67 237.0 28KKN@1|root,2ZA5E@2|Bacteria,4NMKH@976|Bacteroidetes,47PT5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7100333_0 1120966.AUBU01000001_gene1265 3.062e-210 661.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,4NESX@976|Bacteroidetes,47JG6@768503|Cytophagia 976|Bacteroidetes F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase CMS3_k127_710518_3 373994.Riv7116_1913 1.321e-47 184.0 COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales 1117|Cyanobacteria S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - CHAT,COR,LRR_4,LRR_8,Roc CMS3_k127_710518_6 1121904.ARBP01000007_gene3111 1.085e-05 57.0 COG2319@1|root,COG2319@2|Bacteria,4PP7D@976|Bacteroidetes,47WB4@768503|Cytophagia 976|Bacteroidetes S TIR domain - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - TIR_2 CMS3_k127_710518_2 1121904.ARBP01000014_gene12 5.349e-118 392.0 COG1914@1|root,COG1914@2|Bacteria,4NENE@976|Bacteroidetes,47KBJ@768503|Cytophagia 976|Bacteroidetes P Natural resistance-associated macrophage protein - - - - - - - - - - - - Nramp CMS3_k127_710518_1 562970.Btus_3078 7.702e-141 454.0 COG0451@1|root,COG0451@2|Bacteria,1TPHV@1239|Firmicutes,4HCJR@91061|Bacilli 91061|Bacilli GM epimerase - - - - - - - - - - - - Epimerase CMS3_k127_710518_0 1121904.ARBP01000014_gene14 5.851e-152 488.0 COG0329@1|root,COG0329@2|Bacteria,4NH72@976|Bacteroidetes,47NPU@768503|Cytophagia 976|Bacteroidetes EM Dihydrodipicolinate synthetase family - - - - - - - - - - - - DHDPS CMS3_k127_710518_4 880070.Cycma_0515 2.291e-42 167.0 COG0454@1|root,COG0456@2|Bacteria,4NT7Q@976|Bacteroidetes,47VTT@768503|Cytophagia 976|Bacteroidetes K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 CMS3_k127_710518_5 1123248.KB893359_gene2084 2.584e-28 116.0 COG0673@1|root,COG0673@2|Bacteria,4NG5E@976|Bacteroidetes,1IUTT@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_7116026_0 525373.HMPREF0766_10244 5.976e-261 812.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1IPA1@117747|Sphingobacteriia 976|Bacteroidetes J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind CMS3_k127_7116026_1 984262.SGRA_3314 3.04e-86 325.0 COG3291@1|root,COG3291@2|Bacteria,4NPCA@976|Bacteroidetes 976|Bacteroidetes S COG3291 FOG PKD repeat - - - - - - - - - - - - CHU_C,PKD CMS3_k127_7116026_2 984262.SGRA_1328 9.629e-65 247.0 COG2132@1|root,COG3209@1|root,COG2132@2|Bacteria,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - CHU_C,Copper-bind,Cu-oxidase_3,PKD,SprB CMS3_k127_7120536_3 1408473.JHXO01000001_gene2449 2.049e-90 303.0 COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,2FW6T@200643|Bacteroidia 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - Transcrip_reg CMS3_k127_7120536_0 1089547.KB913013_gene1097 1.755e-273 848.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,47K3E@768503|Cytophagia 976|Bacteroidetes I Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) pccB - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS3_k127_7120536_2 929556.Solca_3939 2.159e-151 490.0 COG1231@1|root,COG1231@2|Bacteria,4NGST@976|Bacteroidetes,1J0C4@117747|Sphingobacteriia 976|Bacteroidetes E Flavin containing amine oxidoreductase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase CMS3_k127_7120536_7 1296416.JACB01000026_gene3947 2.955e-11 70.0 28SFS@1|root,2ZESA@2|Bacteria,4P7CE@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7120536_1 1121904.ARBP01000032_gene2003 1.702e-180 572.0 COG0667@1|root,COG0667@2|Bacteria 2|Bacteria C Aldo Keto reductase - - - - - - - - - - - - Aldo_ket_red,EcsC CMS3_k127_7120536_4 929556.Solca_2063 2.6e-69 240.0 COG3358@1|root,COG3358@2|Bacteria,4NNWJ@976|Bacteroidetes,1ITID@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 CMS3_k127_7120536_5 1242864.D187_007986 1.498e-20 105.0 COG1994@1|root,COG1994@2|Bacteria,1PC66@1224|Proteobacteria,433UK@68525|delta/epsilon subdivisions,2XA3T@28221|Deltaproteobacteria,2YWAR@29|Myxococcales 28221|Deltaproteobacteria S Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 CMS3_k127_7120536_6 307480.IW16_21030 5.546e-16 86.0 2BYHP@1|root,3173V@2|Bacteria,4NRHP@976|Bacteroidetes,1I351@117743|Flavobacteriia,3ZRGH@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7120543_3 261292.Nit79A3_2443 1.332e-27 125.0 COG3291@1|root,COG3291@2|Bacteria,1PWG0@1224|Proteobacteria,2WC0Q@28216|Betaproteobacteria,3744F@32003|Nitrosomonadales 28216|Betaproteobacteria S Pkd domain containing protein - - - - - - - - - - - - - CMS3_k127_7120543_0 1408473.JHXO01000004_gene207 2.772e-126 412.0 COG1453@1|root,COG1453@2|Bacteria,4NGCW@976|Bacteroidetes,2FPG8@200643|Bacteroidia 976|Bacteroidetes S Tat pathway signal sequence domain protein - - - ko:K07079 - - - - ko00000 - - - Aldo_ket_red,Fer4_17 CMS3_k127_7120543_2 469382.Hbor_16090 7.857e-36 151.0 arCOG09395@1|root,arCOG09395@2157|Archaea,2XTUR@28890|Euryarchaeota,23S6T@183963|Halobacteria 183963|Halobacteria S Protein of unknown function (DUF3179) - - - - - - - - - - - - DUF3179 CMS3_k127_7120543_1 118168.MC7420_7640 2.448e-45 174.0 COG4249@1|root,COG4249@2|Bacteria,1G42B@1117|Cyanobacteria,1H7VS@1150|Oscillatoriales 1117|Cyanobacteria S Caspase domain - - - - - - - - - - - - PGAP1,Peptidase_C14 CMS3_k127_7137240_0 1002339.HMPREF9373_1241 2.332e-05 57.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,3NIKG@468|Moraxellaceae 1236|Gammaproteobacteria O Belongs to the peptidase S1C family mucD GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 CMS3_k127_7139156_0 1313301.AUGC01000012_gene1302 5.822e-223 700.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes 976|Bacteroidetes F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH CMS3_k127_7139156_2 1121481.AUAS01000006_gene636 3.582e-43 171.0 COG0392@1|root,COG0392@2|Bacteria,4NGPD@976|Bacteroidetes,47JZY@768503|Cytophagia 976|Bacteroidetes S PFAM Uncharacterised protein family (UPF0104) - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM CMS3_k127_7139156_1 365046.Rta_33810 2.628e-46 171.0 COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2VQFV@28216|Betaproteobacteria,4ADKH@80864|Comamonadaceae 28216|Betaproteobacteria I PFAM MaoC domain protein dehydratase - - - - - - - - - - - - MaoC_dehydratas CMS3_k127_7139156_3 1173022.Cri9333_3899 7.76e-27 116.0 COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1H9ZU@1150|Oscillatoriales 1117|Cyanobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2 CMS3_k127_7144694_0 1356852.N008_07175 2.144e-152 494.0 COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47MD4@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1800) - - - - - - - - - - - - DUF1800 CMS3_k127_7144694_1 471854.Dfer_5700 1.912e-142 459.0 COG0524@1|root,COG0524@2|Bacteria,4NH9X@976|Bacteroidetes,47JV1@768503|Cytophagia 976|Bacteroidetes G pfkB family carbohydrate kinase - - 2.7.1.4,2.7.1.92 ko:K00847,ko:K03338 ko00051,ko00500,ko00520,ko00562,ko01100,ko01120,map00051,map00500,map00520,map00562,map01100,map01120 - R00760,R00867,R03920,R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB CMS3_k127_7144694_2 1210884.HG799465_gene11440 2.51e-23 105.0 28WG9@1|root,2ZIGE@2|Bacteria 2|Bacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 CMS3_k127_7144694_3 694427.Palpr_0914 1.472e-22 107.0 2AB14@1|root,339IP@2|Bacteria,4NZD5@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7160324_4 313596.RB2501_09140 9.105e-69 245.0 COG1503@1|root,COG1503@2|Bacteria,4NHJS@976|Bacteroidetes,1I0YD@117743|Flavobacteriia 976|Bacteroidetes J translation release factor activity - - - - - - - - - - - - - CMS3_k127_7160324_0 1189619.pgond44_06560 2.675e-306 950.0 COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1HZTD@117743|Flavobacteriia,4C3KE@83612|Psychroflexus 976|Bacteroidetes C Aconitase family (aconitate hydratase) - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C CMS3_k127_7160324_7 269799.Gmet_1200 1.31e-07 64.0 COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria,1MUIQ@1224|Proteobacteria,42XEE@68525|delta/epsilon subdivisions,2WT63@28221|Deltaproteobacteria 28221|Deltaproteobacteria S CHAT domain - - - - - - - - - - - - CHAT,LCAT CMS3_k127_7160324_1 929556.Solca_2578 1.941e-150 494.0 COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia 976|Bacteroidetes M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 CMS3_k127_7160324_2 313606.M23134_07664 2.441e-141 467.0 2CIBF@1|root,2Z85N@2|Bacteria,4NF0J@976|Bacteroidetes,47TPV@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7160324_6 1453500.AT05_05495 1.776e-36 149.0 2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes 976|Bacteroidetes S Outer membrane protein Omp28 - - - - - - - - - - - - Omp28 CMS3_k127_7160324_3 1313301.AUGC01000005_gene373 9.843e-105 384.0 COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4NGRJ@976|Bacteroidetes 976|Bacteroidetes O PFAM Pregnancy-associated plasma protein-A - - - - - - - - - - - - Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3 CMS3_k127_7160324_5 313606.M23134_05596 3.054e-45 190.0 COG2353@1|root,COG3291@1|root,COG4447@1|root,COG5492@1|root,COG2353@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG5492@2|Bacteria,4PKMF@976|Bacteroidetes,47QU9@768503|Cytophagia 976|Bacteroidetes N cellulose binding - - - - - - - - - - - - - CMS3_k127_7163066_1 1168034.FH5T_17650 1.522e-41 160.0 COG1595@1|root,COG1595@2|Bacteria,4NVR6@976|Bacteroidetes 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2 CMS3_k127_7163066_2 760192.Halhy_3428 4.526e-19 96.0 COG4783@1|root,COG4783@2|Bacteria,4NM73@976|Bacteroidetes,1IU03@117747|Sphingobacteriia 976|Bacteroidetes S chaperone-mediated protein folding - - - - - - - - - - - - ANAPC3,TPR_16,TPR_19 CMS3_k127_7163066_0 1121904.ARBP01000033_gene3182 2.651e-59 221.0 COG0860@1|root,COG0860@2|Bacteria 2|Bacteria M N-Acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448,ko:K02172 ko01501,ko01503,map01501,map01503 M00627,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036 - - - Amidase_3,Cu_amine_oxidN1 CMS3_k127_7166373_1 1116472.MGMO_176c00140 1.624e-122 401.0 COG1577@1|root,COG1577@2|Bacteria 2|Bacteria I mevalonate kinase activity mvaK2 - 2.7.1.36,2.7.1.43,2.7.4.2 ko:K00869,ko:K00938,ko:K16190 ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146 M00014,M00095 R01476,R02245,R03245 RC00002,RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CMS3_k127_7166373_0 313606.M23134_07002 3.124e-185 595.0 COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - - - - - - - - - - SSF CMS3_k127_7166373_2 1123276.KB893255_gene1816 2.599e-111 372.0 COG2072@1|root,COG2072@2|Bacteria,4NGC0@976|Bacteroidetes,47N3G@768503|Cytophagia 976|Bacteroidetes P Flavin-binding monooxygenase-like - - 1.14.13.168 ko:K11816 ko00380,ko01100,map00380,map01100 - R10181 RC00866 ko00000,ko00001,ko01000 - - - FMO-like,Pyr_redox_3 CMS3_k127_7166373_3 1121935.AQXX01000113_gene1456 2.46e-76 271.0 COG2304@1|root,COG2304@2|Bacteria,1RF16@1224|Proteobacteria,1SZ3Z@1236|Gammaproteobacteria 1236|Gammaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - VWA CMS3_k127_7191553_0 1313301.AUGC01000009_gene1004 4.979e-273 860.0 COG4206@1|root,COG4206@2|Bacteria,4PM6D@976|Bacteroidetes 976|Bacteroidetes H TonB-dependent Receptor Plug Domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_7191553_1 1121957.ATVL01000008_gene4187 1.145e-22 109.0 2B6TM@1|root,31ZSX@2|Bacteria,4NRFX@976|Bacteroidetes,47QB9@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4249) - - - - - - - - - - - - DUF4249 CMS3_k127_7201503_1 243090.RB607 2.121e-97 331.0 COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A and related enzymes - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase CMS3_k127_7201503_0 641524.ADICYQ_5433 1.395e-204 645.0 COG3119@1|root,COG3119@2|Bacteria,4NFGI@976|Bacteroidetes,47TD0@768503|Cytophagia 976|Bacteroidetes P Protein of unknown function (DUF229) - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_7201734_3 866536.Belba_0040 0.0008562 43.0 COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,47J9P@768503|Cytophagia 976|Bacteroidetes V ABC-type antimicrobial peptide transport system, permease component - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7201734_1 991.IW20_21095 5.565e-77 267.0 COG0484@1|root,COG0484@2|Bacteria,4NE4X@976|Bacteroidetes,1HXJ8@117743|Flavobacteriia,2NTKH@237|Flavobacterium 976|Bacteroidetes O Molecular chaperone DnaJ dnaJ2 - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C CMS3_k127_7201734_2 471854.Dfer_1930 2.039e-10 64.0 COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,47Q9R@768503|Cytophagia 976|Bacteroidetes M PFAM GCN5-related N-acetyltransferase - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 CMS3_k127_7201734_0 1239962.C943_04530 2.369e-85 288.0 COG1235@1|root,COG1235@2|Bacteria,4NDWB@976|Bacteroidetes,47JF0@768503|Cytophagia 976|Bacteroidetes S of the beta-lactamase superfamily I phnP - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 CMS3_k127_7204272_4 760192.Halhy_3112 5.289e-18 86.0 2AE47@1|root,313XF@2|Bacteria,4NYMZ@976|Bacteroidetes 976|Bacteroidetes S Domain of unknown function (DUF4160) - - - - - - - - - - - - DUF4160 CMS3_k127_7204272_1 1121895.Q765_16920 5.782e-83 284.0 COG2996@1|root,COG2996@2|Bacteria,4NGS6@976|Bacteroidetes,1HYJ6@117743|Flavobacteriia,2NS9P@237|Flavobacterium 976|Bacteroidetes S GntR family transcriptional regulator yitL - - ko:K00243 - - - - ko00000 - - - S1_2 CMS3_k127_7204272_2 755732.Fluta_2872 6.964e-80 273.0 COG3527@1|root,COG3527@2|Bacteria,4NKWJ@976|Bacteroidetes,1HX22@117743|Flavobacteriia 976|Bacteroidetes Q Alpha-acetolactate decarboxylase alsD - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy CMS3_k127_7204272_0 1121904.ARBP01000004_gene1091 1.353e-203 661.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47JJN@768503|Cytophagia 976|Bacteroidetes V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS3_k127_7204272_3 1296416.JACB01000055_gene3643 2.85e-49 182.0 COG0457@1|root,COG0457@2|Bacteria,4NNWA@976|Bacteroidetes,1I350@117743|Flavobacteriia,2YI6K@290174|Aquimarina 976|Bacteroidetes S Tetratricopeptide repeat - - - - - - - - - - - - - CMS3_k127_7210089_7 1168034.FH5T_07405 1.608e-18 97.0 COG0038@1|root,COG0038@2|Bacteria,4NZYS@976|Bacteroidetes,2G0DB@200643|Bacteroidia 976|Bacteroidetes P Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 CMS3_k127_7210089_1 153721.MYP_4541 5.055e-72 251.0 COG0566@1|root,COG0566@2|Bacteria,4NF6H@976|Bacteroidetes,47JZC@768503|Cytophagia 976|Bacteroidetes J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH - 2.1.1.185 ko:K03218,ko:K03437 - - - - ko00000,ko01000,ko03009,ko03016 - - - SpoU_methylase,SpoU_sub_bind CMS3_k127_7210089_4 1120951.AUBG01000009_gene2845 7.585e-30 124.0 COG5499@1|root,COG5499@2|Bacteria,4NQVN@976|Bacteroidetes,1I603@117743|Flavobacteriia 976|Bacteroidetes K Helix-turn-helix XRE-family like proteins - - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - HTH_3 CMS3_k127_7210089_2 655815.ZPR_0734 6.253e-41 152.0 COG4115@1|root,COG4115@2|Bacteria,4NSJD@976|Bacteroidetes,1I67M@117743|Flavobacteriia 976|Bacteroidetes S YoeB-like toxin of bacterial type II toxin-antitoxin system - - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin CMS3_k127_7210089_6 1453505.JASY01000002_gene2353 3.649e-26 109.0 COG2161@1|root,COG2161@2|Bacteria,4NT64@976|Bacteroidetes,1I6PT@117743|Flavobacteriia,2NXYM@237|Flavobacterium 976|Bacteroidetes D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox CMS3_k127_7210089_3 1237149.C900_01017 6.388e-40 152.0 COG2402@1|root,COG2402@2|Bacteria 2|Bacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - ko:K07065 - - - - ko00000 - - - PIN,PIN_3 CMS3_k127_7210089_5 1237149.C900_01016 8.132e-30 120.0 2DMNP@1|root,32SQ4@2|Bacteria,4NT2A@976|Bacteroidetes,47WCH@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7210089_0 1121904.ARBP01000002_gene6906 3.462e-127 418.0 COG2319@1|root,COG2319@2|Bacteria,4NNKN@976|Bacteroidetes,47Q0D@768503|Cytophagia 976|Bacteroidetes S WD40 repeats - - - - - - - - - - - - WD40 CMS3_k127_7211195_3 1237149.C900_03649 1.405e-89 312.0 COG2203@1|root,COG3292@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,4NK8Q@976|Bacteroidetes,47M6U@768503|Cytophagia 976|Bacteroidetes KT PFAM Y_Y_Y domain - - - - - - - - - - - - GAF_2,HATPase_c,HTH_18,HisKA,HisKA_2,Reg_prop,Response_reg,SpoIIE,Y_Y_Y CMS3_k127_7211195_2 1121904.ARBP01000028_gene1698 5.329e-115 379.0 COG2972@1|root,COG3437@1|root,COG2972@2|Bacteria,COG3437@2|Bacteria,4NP14@976|Bacteroidetes,47Q84@768503|Cytophagia 976|Bacteroidetes KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg,SpoIIE CMS3_k127_7211195_1 1121904.ARBP01000009_gene4223 1.175e-142 461.0 COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,4NF1F@976|Bacteroidetes,47MSJ@768503|Cytophagia 976|Bacteroidetes T Adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg CMS3_k127_7211195_0 1408433.JHXV01000010_gene585 2.341e-147 471.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,1HWSA@117743|Flavobacteriia,2PAH9@246874|Cryomorphaceae 976|Bacteroidetes C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N CMS3_k127_7214166_5 641491.DND132_1124 2.079e-83 284.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2MC7X@213115|Desulfovibrionales 28221|Deltaproteobacteria E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS3_k127_7214166_6 760192.Halhy_1377 9.569e-71 259.0 COG3428@1|root,COG3428@2|Bacteria,4NJ1E@976|Bacteroidetes,1IZ3X@117747|Sphingobacteriia 976|Bacteroidetes S Bacterial PH domain - - - ko:K08981 - - - - ko00000 - - - bPH_2 CMS3_k127_7214166_8 926562.Oweho_0309 6.096e-34 136.0 COG3402@1|root,COG3402@2|Bacteria,4NUVJ@976|Bacteroidetes,1I2NQ@117743|Flavobacteriia 976|Bacteroidetes S Bacterial PH domain - - - ko:K09167 - - - - ko00000 - - - bPH_2 CMS3_k127_7214166_4 1380384.JADN01000004_gene2082 2.448e-89 304.0 COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,1HXQ5@117743|Flavobacteriia 976|Bacteroidetes H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase CMS3_k127_7214166_7 1121904.ARBP01000002_gene6946 5.457e-69 241.0 COG0130@1|root,COG0130@2|Bacteria,4NESK@976|Bacteroidetes,47P98@768503|Cytophagia 976|Bacteroidetes J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C_2,TruB_N CMS3_k127_7214166_2 443144.GM21_1759 4.659e-137 445.0 COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria 28221|Deltaproteobacteria M glycosyl transferase group 1 - - - - - - - - - - - - DUF3524,Glycos_transf_1 CMS3_k127_7214166_0 1120968.AUBX01000015_gene3663 1.277e-250 786.0 COG1960@1|root,COG1960@2|Bacteria,4NG2G@976|Bacteroidetes,47KH2@768503|Cytophagia 976|Bacteroidetes I acyl-CoA dehydrogenase fadE - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_7214166_3 1317122.ATO12_02245 2.884e-129 419.0 COG1131@1|root,COG1131@2|Bacteria,4NFWM@976|Bacteroidetes,1HXEB@117743|Flavobacteriia,2YJ27@290174|Aquimarina 976|Bacteroidetes V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran CMS3_k127_7214166_1 880071.Fleli_3804 2.414e-245 784.0 COG0308@1|root,COG0308@2|Bacteria,4NF3R@976|Bacteroidetes,47N7W@768503|Cytophagia 976|Bacteroidetes E Peptidase family M1 domain - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4,Peptidase_M1 CMS3_k127_7222606_0 760192.Halhy_0732 0.0 1167.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia 976|Bacteroidetes C Pyrrolo-quinoline quinone - - - - - - - - - - - - Cytochrome_CBB3,PQQ CMS3_k127_7222606_4 760192.Halhy_0731 2.786e-208 652.0 COG0662@1|root,COG3837@1|root,COG0662@2|Bacteria,COG3837@2|Bacteria,4NHX8@976|Bacteroidetes 976|Bacteroidetes G Cupin domain - - - - - - - - - - - - Cupin_2 CMS3_k127_7222606_2 760192.Halhy_0729 2.377e-310 955.0 COG5434@1|root,COG5434@2|Bacteria,4NE4H@976|Bacteroidetes 976|Bacteroidetes M Belongs to the glycosyl hydrolase 28 family - - - - - - - - - - - - - CMS3_k127_7222606_1 760192.Halhy_0725 0.0 1053.0 COG1917@1|root,COG3386@1|root,COG1917@2|Bacteria,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1IRQS@117747|Sphingobacteriia 976|Bacteroidetes G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL CMS3_k127_7222606_9 1227739.Hsw_2363 8.438e-08 53.0 COG1506@1|root,COG2755@1|root,COG3693@1|root,COG1506@2|Bacteria,COG2755@2|Bacteria,COG3693@2|Bacteria,4PKQ3@976|Bacteroidetes,47XYQ@768503|Cytophagia 976|Bacteroidetes E lipolytic protein G-D-S-L family - - - - - - - - - - - - CBM9_1,Peptidase_S9 CMS3_k127_7222606_7 234267.Acid_2073 3.834e-87 301.0 COG0296@1|root,COG2382@1|root,COG0296@2|Bacteria,COG2382@2|Bacteria,3Y6V1@57723|Acidobacteria 57723|Acidobacteria GP Belongs to the glycosyl hydrolase 13 family - - - ko:K07214 - - - - ko00000 - - - CBM_48,Esterase CMS3_k127_7222606_8 1123277.KB893244_gene5054 1.045e-29 123.0 COG4319@1|root,COG4319@2|Bacteria,4NSGY@976|Bacteroidetes,47RCI@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 CMS3_k127_7222606_6 398720.MED217_12344 1.852e-176 574.0 COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,1HZE1@117743|Flavobacteriia,2XI60@283735|Leeuwenhoekiella 2|Bacteria G Alpha-L-arabinofuranosidase C-terminus - - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C CMS3_k127_7222606_5 760192.Halhy_0724 1.181e-183 578.0 COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1IR2I@117747|Sphingobacteriia 976|Bacteroidetes H SPTR Demethylmenaquinone methyltransferase-like protein - - - - - - - - - - - - RraA-like CMS3_k127_7222606_3 760192.Halhy_0723 8.602e-255 788.0 COG4948@1|root,COG4948@2|Bacteria,4NIIJ@976|Bacteroidetes,1IPCK@117747|Sphingobacteriia 976|Bacteroidetes M PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal - - 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_7256776_0 563031.HMPREF0666_00026 1.303e-130 439.0 COG0443@1|root,COG0443@2|Bacteria,4PJF5@976|Bacteroidetes,2FRM3@200643|Bacteroidia 976|Bacteroidetes O Heat shock 70 kDa protein - - - - - - - - - - - - - CMS3_k127_7256776_2 1236517.BAKO01000010_gene1481 7.673e-18 97.0 2EZHZ@1|root,33SP1@2|Bacteria,4P0S6@976|Bacteroidetes,2FQKR@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7256776_1 1042877.GQS_00090 5.274e-39 155.0 COG0419@1|root,COG0631@1|root,arCOG00368@2157|Archaea,arCOG05302@2157|Archaea,2XZK8@28890|Euryarchaeota,243WM@183968|Thermococci 183968|Thermococci T Sigma factor PP2C-like phosphatases - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C CMS3_k127_7256776_4 56110.Oscil6304_5180 7.863e-12 65.0 COG3744@1|root,COG3744@2|Bacteria,1G60Y@1117|Cyanobacteria,1HBDD@1150|Oscillatoriales 1117|Cyanobacteria S PIN domain - - - - - - - - - - - - PIN CMS3_k127_7256776_3 1286632.P278_14550 7.322e-14 73.0 COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1I039@117743|Flavobacteriia 976|Bacteroidetes T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - CHASE3,Guanylate_cyc,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12 CMS3_k127_7267819_0 1189612.A33Q_2303 2.881e-320 1001.0 COG0178@1|root,COG0178@2|Bacteria,4NEHM@976|Bacteroidetes,47JVJ@768503|Cytophagia 976|Bacteroidetes L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA1 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - AAA_21,ABC_tran CMS3_k127_7267819_4 929556.Solca_2960 2.829e-63 223.0 COG1595@1|root,COG1595@2|Bacteria,4NF93@976|Bacteroidetes,1INYP@117747|Sphingobacteriia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily rpoE - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS3_k127_7267819_7 1123057.P872_08235 1.116e-05 54.0 2DQSK@1|root,338E4@2|Bacteria,4NX60@976|Bacteroidetes,47SKZ@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7267819_3 760192.Halhy_3810 8.062e-104 347.0 COG1208@1|root,COG1208@2|Bacteria,4NIRW@976|Bacteroidetes,1IVAZ@117747|Sphingobacteriia 976|Bacteroidetes JM Nucleotidyl transferase - - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase CMS3_k127_7267819_1 1499685.CCFJ01000022_gene2370 5.336e-150 481.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HAZ2@91061|Bacilli,1ZQGA@1386|Bacillus 91061|Bacilli C Aldo/keto reductase family yghZ - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red CMS3_k127_7267819_6 562983.HMPREF0433_00838 1.366e-23 117.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,3WEAF@539002|Bacillales incertae sedis 91061|Bacilli P ABC transporter, phosphonate, periplasmic substrate-binding protein phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd CMS3_k127_7267819_2 926562.Oweho_1533 3.165e-129 422.0 COG0276@1|root,COG0276@2|Bacteria,4NE83@976|Bacteroidetes,1HXUV@117743|Flavobacteriia,2PAT3@246874|Cryomorphaceae 976|Bacteroidetes H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase CMS3_k127_7267819_5 1121889.AUDM01000003_gene2283 1.224e-47 175.0 COG2207@1|root,COG2207@2|Bacteria,4NEEQ@976|Bacteroidetes,1HXZM@117743|Flavobacteriia,2NSWQ@237|Flavobacterium 976|Bacteroidetes K AraC family transcriptional regulator - - - - - - - - - - - - HTH_18 CMS3_k127_7269847_3 760192.Halhy_2091 4.418e-16 81.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system - - - ko:K19092 - - - - ko00000,ko02048 - - - ParE_toxin CMS3_k127_7269847_0 1379270.AUXF01000001_gene2163 2.323e-193 614.0 COG1387@1|root,COG1387@2|Bacteria 2|Bacteria E zinc ion binding - - - - - - - - - - - - CHB_HEX_C_1,PHP CMS3_k127_7269847_1 235909.GK3178 2.057e-51 187.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HH1N@91061|Bacilli 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii CMS3_k127_7269847_2 198467.NP92_02125 1.818e-42 162.0 COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,4HGQX@91061|Bacilli 91061|Bacilli K Psort location Cytoplasmic, score - - - - - - - - - - - - AbiEi_4 CMS3_k127_7279747_3 1123277.KB893178_gene2627 1.277e-110 362.0 COG1028@1|root,COG1028@2|Bacteria,4NHVK@976|Bacteroidetes,47K2F@768503|Cytophagia 976|Bacteroidetes IQ PFAM Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 CMS3_k127_7279747_1 1123248.KB893318_gene4120 2.842e-205 644.0 COG0673@1|root,COG0673@2|Bacteria,4NKJ1@976|Bacteroidetes,1IVPJ@117747|Sphingobacteriia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_7279747_4 760192.Halhy_3735 3.442e-106 350.0 COG1082@1|root,COG1082@2|Bacteria,4NHJE@976|Bacteroidetes,1IWGQ@117747|Sphingobacteriia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_7279747_2 946077.W5A_06975 8.11e-139 451.0 COG0626@1|root,COG0626@2|Bacteria,4PKE6@976|Bacteroidetes,1IJ8Q@117743|Flavobacteriia 976|Bacteroidetes E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP CMS3_k127_7279747_0 761193.Runsl_0862 1.159e-225 706.0 COG4225@1|root,COG4225@2|Bacteria,4NJYK@976|Bacteroidetes,47MFS@768503|Cytophagia 976|Bacteroidetes S Glycosyl Hydrolase Family 88 - - 3.2.1.180 ko:K18581 - - R10867 RC00049,RC02427 ko00000,ko01000 - GH88 - Glyco_hydro_88 CMS3_k127_7279747_6 880070.Cycma_3803 8.402e-47 178.0 COG3828@1|root,COG3828@2|Bacteria,4NEWH@976|Bacteroidetes,47P36@768503|Cytophagia 976|Bacteroidetes S Methane oxygenase PmoA - - - - - - - - - - - - PmoA CMS3_k127_7279747_5 519989.ECTPHS_11110 1.241e-100 331.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales 135613|Chromatiales E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CMS3_k127_7292382_0 1279009.ADICEAN_03328 8.943e-126 409.0 COG0332@1|root,COG0332@2|Bacteria,4NEWU@976|Bacteroidetes,47KNB@768503|Cytophagia 976|Bacteroidetes I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_7292382_2 1168034.FH5T_04700 1.143e-35 149.0 COG1295@1|root,COG1295@2|Bacteria,4NFY6@976|Bacteroidetes 976|Bacteroidetes S ribonuclease BN yfkH - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CMS3_k127_7292382_1 761193.Runsl_5479 7.99e-38 145.0 COG0824@1|root,COG0824@2|Bacteria,4NQGW@976|Bacteroidetes,47Q99@768503|Cytophagia 976|Bacteroidetes S TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family ybgC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 CMS3_k127_7292382_4 1123277.KB893228_gene2120 1.385e-25 109.0 COG0607@1|root,COG0607@2|Bacteria,4NVM6@976|Bacteroidetes,47RAG@768503|Cytophagia 976|Bacteroidetes P PFAM Rhodanese-like domain - - - - - - - - - - - - Rhodanese CMS3_k127_7292382_3 491205.JARQ01000001_gene1211 5.962e-27 110.0 COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,1HWMK@117743|Flavobacteriia,3ZNTW@59732|Chryseobacterium 976|Bacteroidetes J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C CMS3_k127_7293888_0 1279009.ADICEAN_00242 5.333e-112 373.0 COG1215@1|root,COG1215@2|Bacteria,4NEG0@976|Bacteroidetes,47KET@768503|Cytophagia 976|Bacteroidetes M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_7293888_1 1270196.JCKI01000005_gene2987 6.089e-06 53.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NHKC@976|Bacteroidetes 976|Bacteroidetes M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - AAA_31,Wzz CMS3_k127_7300365_5 1123248.KB893348_gene72 1.712e-11 65.0 COG4804@1|root,COG4804@2|Bacteria,4NGY8@976|Bacteroidetes,1IRN5@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function (DUF1016) - - - - - - - - - - - - DUF1016 CMS3_k127_7300365_1 1168034.FH5T_12335 9.855e-75 263.0 COG1226@1|root,COG1226@2|Bacteria,4NG7W@976|Bacteroidetes,2FYAQ@200643|Bacteroidia 976|Bacteroidetes P Ion channel - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_C,TrkA_N CMS3_k127_7300365_0 504472.Slin_4218 2.441e-107 374.0 COG3291@1|root,COG3291@2|Bacteria,4NGRJ@976|Bacteroidetes,47NXA@768503|Cytophagia 976|Bacteroidetes O Pregnancy-associated plasma protein-A - - - - - - - - - - - - Calx-beta,Cleaved_Adhesin,PKD,Peptidase_M43,fn3 CMS3_k127_7300365_4 1122176.KB903552_gene3713 1.693e-29 122.0 COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,1ITVQ@117747|Sphingobacteriia 976|Bacteroidetes M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar CMS3_k127_7300365_2 509635.N824_13935 6.591e-65 236.0 COG0402@1|root,COG0402@2|Bacteria,4NJVU@976|Bacteroidetes,1IPAQ@117747|Sphingobacteriia 976|Bacteroidetes F amidohydrolase - - 3.5.4.40 ko:K20810 ko00130,ko01110,map00130,map01110 - R10695 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 CMS3_k127_7300365_3 1123058.KB894240_gene2054 1.257e-37 145.0 COG0727@1|root,COG0727@2|Bacteria,4NEPX@976|Bacteroidetes,1HXTT@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF3109) - - - - - - - - - - - - DUF3109 CMS3_k127_7306499_8 265729.GS18_0221835 0.0005673 46.0 COG0457@1|root,COG3271@1|root,COG4783@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,COG4783@2|Bacteria,1TQUB@1239|Firmicutes,4HDBA@91061|Bacilli,1ZBGT@1386|Bacillus 91061|Bacilli H Papain-like cysteine protease AvrRpt2 - - - - - - - - - - - - Peptidase_C39_2,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8 CMS3_k127_7306499_6 1122179.KB890422_gene2234 1.042e-14 80.0 COG1470@1|root,COG3291@1|root,COG1470@2|Bacteria,COG3291@2|Bacteria,4NDZC@976|Bacteroidetes,1ISXD@117747|Sphingobacteriia 976|Bacteroidetes M C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C,DUF11,SprB CMS3_k127_7306499_3 1122176.KB903536_gene1853 2.947e-37 162.0 COG3210@1|root,COG5295@1|root,COG3210@2|Bacteria,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein - - - - - - - - - - - - CHU_C,DUF4347,He_PIG,PATR,SLH CMS3_k127_7306499_5 1408813.AYMG01000023_gene2141 1.894e-17 97.0 COG3210@1|root,COG3266@1|root,COG4675@1|root,COG4733@1|root,COG5295@1|root,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4675@2|Bacteria,COG4733@2|Bacteria,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein - - - ko:K12056 - - - - ko00000,ko02044 3.A.7.11.1 - - Collagen,DUF4347,YadA_stalk CMS3_k127_7306499_4 1122176.KB903536_gene1850 2.082e-20 102.0 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - - - - - - - - - - - Antigen_C,DUF4150,PorP_SprF CMS3_k127_7306499_1 388413.ALPR1_17748 6.452e-91 307.0 COG0657@1|root,COG0657@2|Bacteria,4NGAF@976|Bacteroidetes,47NN7@768503|Cytophagia 976|Bacteroidetes I Protein of unknown function (DUF1460) - - - - - - - - - - - - DUF1460 CMS3_k127_7306499_2 1313421.JHBV01000023_gene5159 6.084e-53 194.0 COG1183@1|root,COG1183@2|Bacteria 2|Bacteria I phosphatidylcholine synthase activity pcs GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 ko:K01004,ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800,R05794 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf CMS3_k127_7306499_0 1124780.ANNU01000062_gene557 3.798e-95 317.0 COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia 976|Bacteroidetes V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_7306499_7 289376.THEYE_A0520 2.063e-06 55.0 2E47H@1|root,32Z3D@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_7307759_0 1347342.BN863_34480 5.007e-190 619.0 COG5009@1|root,COG5009@2|Bacteria,4NECJ@976|Bacteroidetes,1HXWX@117743|Flavobacteriia 976|Bacteroidetes M penicillin-binding protein mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS3_k127_7307759_1 762903.Pedsa_0923 4.058e-65 227.0 COG0163@1|root,COG0163@2|Bacteria,4NIBD@976|Bacteroidetes,1INXX@117747|Sphingobacteriia 976|Bacteroidetes H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein CMS3_k127_7307759_2 649349.Lbys_3023 2.14e-05 53.0 COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,47JE1@768503|Cytophagia 976|Bacteroidetes S Oxygen tolerance - - - - - - - - - - - - BatD CMS3_k127_7310255_1 1122176.KB903544_gene784 2.075e-56 207.0 COG0714@1|root,COG0714@2|Bacteria,4NPWR@976|Bacteroidetes,1IXGZ@117747|Sphingobacteriia 976|Bacteroidetes S SPTR ATPase associated with various cellular activities AAA_5 - - - - - - - - - - - - AAA CMS3_k127_7310255_2 153721.MYP_2249 3.073e-52 199.0 2CG1Y@1|root,2Z9QX@2|Bacteria,4NJI6@976|Bacteroidetes,47PFJ@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 CMS3_k127_7310255_0 1124780.ANNU01000030_gene1135 1.466e-73 255.0 COG0860@1|root,COG0860@2|Bacteria,4NGKC@976|Bacteroidetes,47M2P@768503|Cytophagia 976|Bacteroidetes M N-acetylmuramoyl-L-alanine amidase amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 CMS3_k127_7323977_4 1227739.Hsw_3527 6.178e-60 210.0 COG0251@1|root,COG0251@2|Bacteria,4NMHF@976|Bacteroidetes,47PT2@768503|Cytophagia 976|Bacteroidetes J Endoribonuclease L-PSP - - 3.5.99.5 ko:K15067 ko00380,map00380 - R03887 RC01015 ko00000,ko00001,ko01000 - - - Ribonuc_L-PSP CMS3_k127_7323977_1 153721.MYP_101 3.14e-130 430.0 COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,47MAV@768503|Cytophagia 976|Bacteroidetes E Belongs to the peptidase M24B family pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 CMS3_k127_7323977_2 643867.Ftrac_0551 1.121e-127 415.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,47MGR@768503|Cytophagia 976|Bacteroidetes EF Ribose-phosphate pyrophosphokinase prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N CMS3_k127_7323977_6 1122621.ATZA01000034_gene2897 4.655e-46 173.0 COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,1IRTD@117747|Sphingobacteriia 976|Bacteroidetes J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C CMS3_k127_7323977_3 926549.KI421517_gene1935 1.343e-72 250.0 COG0193@1|root,COG0193@2|Bacteria,4NI7N@976|Bacteroidetes,47Q0M@768503|Cytophagia 976|Bacteroidetes J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro CMS3_k127_7323977_0 1121904.ARBP01000018_gene2615 1.586e-295 914.0 COG0129@1|root,COG0129@2|Bacteria,4NEKY@976|Bacteroidetes,47K3U@768503|Cytophagia 976|Bacteroidetes EG Belongs to the IlvD Edd family - - - - - - - - - - - - ILVD_EDD CMS3_k127_7323977_7 349161.Dred_1413 1.094e-06 59.0 COG1388@1|root,COG1388@2|Bacteria,1UHY7@1239|Firmicutes,24FFK@186801|Clostridia,263QN@186807|Peptococcaceae 186801|Clostridia M Peptidoglycan-binding LysM - - - - - - - - - - - - Cu_amine_oxidN1,LysM,SH3_3 CMS3_k127_7323977_5 388413.ALPR1_08598 2.616e-46 173.0 28M4Q@1|root,2ZAIK@2|Bacteria,4NJC3@976|Bacteroidetes,47P7F@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7328961_3 1250005.PHEL85_1698 1.899e-26 109.0 COG4660@1|root,COG4660@2|Bacteria 2|Bacteria C electron transport chain rnfE GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 2.3.1.243,4.2.99.18 ko:K02560,ko:K03613,ko:K10773 ko00540,ko01100,ko03410,map00540,map01100,map03410 M00060 R05075 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005,ko03400 - - - Rnf-Nqr CMS3_k127_7328961_2 1239962.C943_00087 1.214e-84 286.0 COG4659@1|root,COG4659@2|Bacteria 2|Bacteria C FMN binding - - - ko:K03612 - - - - ko00000 - - - FMN_bind CMS3_k127_7328961_1 1239962.C943_00086 2.121e-157 502.0 COG4658@1|root,COG4658@2|Bacteria,4NESE@976|Bacteroidetes,47XQE@768503|Cytophagia 976|Bacteroidetes U Part of a membrane complex involved in electron transport rnfD - - ko:K03614 - - - - ko00000 - - - NQR2_RnfD_RnfE CMS3_k127_7328961_0 1250005.PHEL85_1695 1.48e-174 550.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,1I7QG@117743|Flavobacteriia 976|Bacteroidetes C Part of a membrane complex involved in electron transport rnfC - - ko:K03615 - - - - ko00000 - - - Complex1_51K,Fer4_10,Fer4_17,Fer4_7,RnfC_N,SLBB CMS3_k127_7330772_14 760192.Halhy_3910 7.376e-07 54.0 COG0662@1|root,COG0662@2|Bacteria,4P9MG@976|Bacteroidetes,1J00S@117747|Sphingobacteriia 976|Bacteroidetes G Cupin domain - - - - - - - - - - - - Cupin_2 CMS3_k127_7330772_10 1218108.KB908298_gene3541 2.119e-13 72.0 2ENFE@1|root,33G2U@2|Bacteria,4NYZ4@976|Bacteroidetes,1I6C9@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7330772_1 760192.Halhy_5684 3.125e-84 282.0 COG2207@1|root,COG2207@2|Bacteria,4NM5G@976|Bacteroidetes,1ISDK@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - - - - - - - - - - HTH_18 CMS3_k127_7330772_4 1121007.AUML01000007_gene2964 2.829e-34 134.0 COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes,1I00H@117743|Flavobacteriia,2YKC6@290174|Aquimarina 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_7330772_0 1121374.KB891586_gene2538 2.448e-104 351.0 COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Sodium hydrogen exchanger - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger CMS3_k127_7330772_3 1392490.JHZX01000001_gene696 5.987e-50 181.0 COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,1I4FM@117743|Flavobacteriia 976|Bacteroidetes S Cupin domain protein - - - - - - - - - - - - Cupin_2 CMS3_k127_7330772_12 517418.Ctha_2386 9.088e-09 59.0 COG1305@1|root,COG1305@2|Bacteria,1FEB8@1090|Chlorobi 1090|Chlorobi E PFAM transglutaminase domain protein - - - - - - - - - - - - Bact_transglu_N,Transglut_core CMS3_k127_7330772_6 1122176.KB903543_gene499 1.214e-27 124.0 COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,1IT9I@117747|Sphingobacteriia 976|Bacteroidetes S PFAM YceI-like domain - - - - - - - - - - - - YceI CMS3_k127_7330772_7 1121007.AUML01000007_gene2974 2.206e-22 97.0 COG1063@1|root,COG1063@2|Bacteria 2|Bacteria E alcohol dehydrogenase adh - 1.1.1.1,1.1.1.14 ko:K00001,ko:K00008,ko:K18369 ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 M00014 R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703 RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00545,RC00649,RC01734,RC02273 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N CMS3_k127_7330772_5 1121373.KB903654_gene1542 7.778e-28 113.0 COG3462@1|root,COG3462@2|Bacteria,4NVJQ@976|Bacteroidetes,47SHH@768503|Cytophagia 976|Bacteroidetes S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT CMS3_k127_7330772_2 1123057.P872_11925 3.624e-60 214.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,47QK5@768503|Cytophagia 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 CMS3_k127_7330772_8 269798.CHU_0498 1.13e-19 91.0 2FKSJ@1|root,34CD3@2|Bacteria,4P89S@976|Bacteroidetes,47WSU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7330772_15 357808.RoseRS_0444 9.651e-07 52.0 COG3385@1|root,COG3385@2|Bacteria,2G9A6@200795|Chloroflexi 200795|Chloroflexi L PFAM transposase, IS4 family protein - - - - - - - - - - - - DDE_Tnp_1 CMS3_k127_7330772_11 1122138.AQUZ01000003_gene465 3.752e-11 71.0 COG4948@1|root,COG4948@2|Bacteria,2I8XX@201174|Actinobacteria,4DT2F@85009|Propionibacteriales 201174|Actinobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C CMS3_k127_7334521_0 1121904.ARBP01000007_gene2953 1.219e-246 782.0 COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia 976|Bacteroidetes G PFAM GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L CMS3_k127_7334521_2 926549.KI421517_gene2982 6.184e-191 612.0 COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,47K2R@768503|Cytophagia 976|Bacteroidetes E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yidK - - - - - - - - - - - SSF CMS3_k127_7334521_6 1150600.ADIARSV_0135 1.85e-23 113.0 28P29@1|root,2ZBYD@2|Bacteria,4NMK6@976|Bacteroidetes,1IRUJ@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7334521_5 760192.Halhy_1229 1.212e-36 143.0 2ASD9@1|root,31HSR@2|Bacteria,4NQ71@976|Bacteroidetes,1IU9P@117747|Sphingobacteriia 976|Bacteroidetes S SMART PUR-alpha beta gamma DNA RNA-binding - - - - - - - - - - - - DUF3276 CMS3_k127_7334521_4 1499967.BAYZ01000060_gene5989 1.085e-88 299.0 COG1864@1|root,COG1864@2|Bacteria,2NRFT@2323|unclassified Bacteria 2|Bacteria F DNA/RNA non-specific endonuclease nucA - - ko:K01173 ko04210,map04210 - - - ko00000,ko00001,ko03029 - - - Endonuclease_NS,Excalibur CMS3_k127_7334521_3 517418.Ctha_0374 6.723e-165 533.0 COG4623@1|root,COG4623@2|Bacteria,1FEDF@1090|Chlorobi 1090|Chlorobi M Bacterial periplasmic substrate-binding proteins - - - ko:K18691 - - - - ko00000,ko01000,ko01011 - - - SBP_bac_3,SLT CMS3_k127_7334521_1 1121904.ARBP01000044_gene2069 1.216e-237 746.0 COG0457@1|root,COG0457@2|Bacteria,4PP65@976|Bacteroidetes 976|Bacteroidetes S Peptidase family M49 - - - - - - - - - - - - Peptidase_M49 CMS3_k127_7335349_0 1454007.JAUG01000112_gene2040 9.485e-130 422.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1INVH@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_7335349_2 1120983.KB894573_gene33 9.3e-70 239.0 COG1917@1|root,COG1917@2|Bacteria,1MUY3@1224|Proteobacteria,2U5R0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel - - - - - - - - - - - - Cupin_7 CMS3_k127_7335349_1 266117.Rxyl_0537 1.487e-79 272.0 COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4CSYH@84995|Rubrobacteria 84995|Rubrobacteria IQ KR domain - - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 CMS3_k127_7336089_0 338966.Ppro_0419 1.031e-280 874.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,43U1C@69541|Desulfuromonadales 28221|Deltaproteobacteria G Belongs to the glycosyl hydrolase 13 family - - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 CMS3_k127_7336089_1 1168034.FH5T_17015 1.003e-28 118.0 COG2827@1|root,COG2827@2|Bacteria,4NUYX@976|Bacteroidetes 976|Bacteroidetes L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS3_k127_7337821_5 485918.Cpin_4081 2.096e-90 299.0 COG2227@1|root,COG2227@2|Bacteria,4PKR9@976|Bacteroidetes,1J0N9@117747|Sphingobacteriia 976|Bacteroidetes H Thiopurine S-methyltransferase (TPMT) - - - - - - - - - - - - Methyltransf_11 CMS3_k127_7337821_1 1132442.KB889752_gene1475 1.237e-246 767.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HD4S@91061|Bacilli,1ZAW5@1386|Bacillus 91061|Bacilli GT phosphoenolpyruvate synthase pps - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N CMS3_k127_7337821_3 616991.JPOO01000003_gene2258 4.982e-169 534.0 COG0388@1|root,COG0388@2|Bacteria,4NGWX@976|Bacteroidetes,1I00B@117743|Flavobacteriia,23HRZ@178469|Arenibacter 976|Bacteroidetes S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase CMS3_k127_7337821_0 1123248.KB893317_gene4298 3.024e-283 878.0 COG2303@1|root,COG2303@2|Bacteria,4NEF2@976|Bacteroidetes,1IWH6@117747|Sphingobacteriia 976|Bacteroidetes E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N CMS3_k127_7337821_6 929562.Emtol_1214 1.144e-16 86.0 2CDAN@1|root,309X8@2|Bacteria,4NP84@976|Bacteroidetes,47Q22@768503|Cytophagia 976|Bacteroidetes S Gluconate 2-dehydrogenase subunit 3 - - - - - - - - - - - - Gluconate_2-dh3 CMS3_k127_7337821_2 1123239.KB898631_gene2323 2.147e-170 544.0 COG4948@1|root,COG4948@2|Bacteria,1U140@1239|Firmicutes,4HAT9@91061|Bacilli 91061|Bacilli M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C CMS3_k127_7337821_4 756272.Plabr_0659 8.047e-168 540.0 COG3119@1|root,COG3119@2|Bacteria,2J2DZ@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - 3.1.6.8 ko:K01134 ko00600,ko04142,map00600,map04142 - R04856 RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C CMS3_k127_733825_0 143224.JQMD01000002_gene1720 1.043e-213 675.0 COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,1HZ9K@117743|Flavobacteriia 976|Bacteroidetes P Domain of unknown function (DUF4976) mdsA - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_733825_2 153721.MYP_330 1.202e-115 387.0 COG0297@1|root,COG0297@2|Bacteria,4PKP8@976|Bacteroidetes,47JA2@768503|Cytophagia 976|Bacteroidetes G Starch synthase catalytic domain - - - - - - - - - - - - Glyco_transf_4,Glyco_transf_5,Glycos_transf_1 CMS3_k127_733825_1 153721.MYP_760 6.59e-136 437.0 COG0438@1|root,COG0438@2|Bacteria,4PKQN@976|Bacteroidetes,47K56@768503|Cytophagia 976|Bacteroidetes M PFAM glycogen synthase - - 2.4.1.11 ko:K00693 ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931 - R00292 RC00005 ko00000,ko00001,ko01000,ko01003 - GT3 - Glycogen_syn CMS3_k127_7339935_6 760192.Halhy_4389 6.631e-11 72.0 2DZKI@1|root,32VD4@2|Bacteria,4P4VD@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7339935_0 761193.Runsl_4419 0.0 1018.0 COG0438@1|root,COG0561@1|root,COG0438@2|Bacteria,COG0561@2|Bacteria,4NJQY@976|Bacteroidetes,47XD7@768503|Cytophagia 976|Bacteroidetes M Sucrose synthase - - 2.4.1.14 ko:K00696 ko00500,ko01100,map00500,map01100 - R00766 RC00005,RC00028,RC02748 ko00000,ko00001,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth CMS3_k127_7339935_1 761193.Runsl_4418 8.026e-218 685.0 COG1621@1|root,COG1621@2|Bacteria,4NKYY@976|Bacteroidetes 976|Bacteroidetes G Glycosyl hydrolases family 32 N-terminal domain - - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N CMS3_k127_7339935_5 1122176.KB903543_gene555 1.677e-11 66.0 COG0828@1|root,COG0828@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 CMS3_k127_7339935_7 1123248.KB893337_gene2455 1.276e-06 57.0 2DSJJ@1|root,33GER@2|Bacteria,4NZAF@976|Bacteroidetes,1IZF5@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7339935_2 761193.Runsl_0234 1.492e-190 604.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_7339935_3 411479.BACUNI_03066 1.503e-157 510.0 COG3119@1|root,COG3119@2|Bacteria,4NEZJ@976|Bacteroidetes,2FMY4@200643|Bacteroidia,4ANE5@815|Bacteroidaceae 976|Bacteroidetes CP COG3119 Arylsulfatase A - - - - - - - - - - - - Sulfatase CMS3_k127_7339935_4 411154.GFO_2983 3.803e-36 139.0 COG0823@1|root,COG0823@2|Bacteria 2|Bacteria U Involved in the tonB-independent uptake of proteins - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - CBM_6,F5_F8_type_C,PD40,SdrD_B CMS3_k127_7345074_0 1166018.FAES_pFAES01022 2.618e-253 800.0 COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes,47MDX@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_7345074_1 1121904.ARBP01000021_gene3615 1.209e-82 278.0 COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PA8@768503|Cytophagia 976|Bacteroidetes C 2Fe-2S -binding domain - - 1.3.99.16 ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_7347331_2 1122176.KB903565_gene3327 3.778e-218 690.0 COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,4NK7Y@976|Bacteroidetes 976|Bacteroidetes C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_11 CMS3_k127_7347331_0 1122176.KB903565_gene3328 0.0 1588.0 COG0243@1|root,COG0243@2|Bacteria,4NITD@976|Bacteroidetes 976|Bacteroidetes C Molybdopterin oxidoreductase - - 1.7.2.3,1.8.5.5 ko:K07812,ko:K08352 ko00920,ko01120,map00920,map01120 - R10149 RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.4,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding CMS3_k127_7347331_7 762903.Pedsa_3652 7.406e-12 69.0 COG0640@1|root,COG0640@2|Bacteria,4NSHB@976|Bacteroidetes,1IZ28@117747|Sphingobacteriia 976|Bacteroidetes K PFAM Bacterial regulatory protein, arsR family - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 CMS3_k127_7347331_3 517418.Ctha_0124 4.288e-157 503.0 COG0535@1|root,COG0535@2|Bacteria 2|Bacteria I radical SAM domain protein - - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,SPASM CMS3_k127_7347331_1 795666.MW7_0904 8.86e-225 716.0 COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VNGR@28216|Betaproteobacteria,1K4ZH@119060|Burkholderiaceae 28216|Betaproteobacteria C 4Fe-4S dicluster domain - - - - - - - - - - - - CCG,Fer4_10,Fer4_8,Nitrate_red_gam CMS3_k127_7347331_4 882083.SacmaDRAFT_1932 6.367e-95 320.0 COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DY2C@85010|Pseudonocardiales 201174|Actinobacteria C Electron transfer flavoprotein alpha subunit etfA - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha,Fer4 CMS3_k127_7347331_5 517418.Ctha_0132 2.323e-72 252.0 COG2086@1|root,COG2086@2|Bacteria 2|Bacteria C electron transfer activity - - - ko:K03521 - - - - ko00000 - - iAF987.Gmet_2266 CCG,ETF,Fer4_8 CMS3_k127_7347331_6 882083.SacmaDRAFT_1930 6.598e-19 89.0 COG2516@1|root,COG2516@2|Bacteria,2H2JZ@201174|Actinobacteria 201174|Actinobacteria S Elongator protein 3, MiaB family, Radical SAM - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM CMS3_k127_7347331_8 1379270.AUXF01000001_gene2437 2.234e-07 52.0 COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUTN@142182|Gemmatimonadetes 142182|Gemmatimonadetes KLT Tetratricopeptide repeat - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase,TPR_8 CMS3_k127_7349832_2 1120953.AUBH01000002_gene1453 1.648e-72 268.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,464U2@72275|Alteromonadaceae 1236|Gammaproteobacteria C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C CMS3_k127_7349832_0 765911.Thivi_3179 3.221e-93 314.0 COG1141@1|root,COG2878@1|root,COG1141@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria,1WWC5@135613|Chromatiales 135613|Chromatiales C Fe-S cluster - - - ko:K03616 - - - - ko00000 - - - FeS,Fer4 CMS3_k127_7349832_1 1049564.TevJSym_bb00030 2.903e-92 332.0 COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria 1224|Proteobacteria C 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - TPP_enzyme_C CMS3_k127_7351801_1 1121904.ARBP01000015_gene179 5.631e-92 312.0 COG0577@1|root,COG0577@2|Bacteria,4NDUK@976|Bacteroidetes,47NTJ@768503|Cytophagia 976|Bacteroidetes V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7351801_2 266748.HY04_05195 9.805e-21 97.0 2F4GJ@1|root,33X6I@2|Bacteria,4P3KU@976|Bacteroidetes,1I98P@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7351801_0 1124780.ANNU01000008_gene2769 3.876e-281 875.0 COG1164@1|root,COG1164@2|Bacteria,4NJFW@976|Bacteroidetes,47TFT@768503|Cytophagia 976|Bacteroidetes E Angiotensin-converting enzyme - - 3.4.15.1 ko:K01283 ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M2 CMS3_k127_7360674_3 1454007.JAUG01000010_gene2555 9.38e-35 138.0 COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes 976|Bacteroidetes J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm CMS3_k127_7360674_2 471852.Tcur_1125 7.906e-50 187.0 COG3850@1|root,COG4251@1|root,COG3850@2|Bacteria,COG4251@2|Bacteria,2GK25@201174|Actinobacteria,4EGPI@85012|Streptosporangiales 201174|Actinobacteria T CHASE3 domain - - - - - - - - - - - - CHASE3,HAMP,HATPase_c,HisKA CMS3_k127_7360674_1 649349.Lbys_1332 2.416e-73 252.0 COG5405@1|root,COG5405@2|Bacteria,4NHZ8@976|Bacteroidetes,47MJS@768503|Cytophagia 976|Bacteroidetes O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome CMS3_k127_7360674_0 1121930.AQXG01000003_gene2559 2.578e-75 258.0 COG1143@1|root,COG1143@2|Bacteria,4NGWR@976|Bacteroidetes,1IRTR@117747|Sphingobacteriia 976|Bacteroidetes C 4Fe-4S ferredoxin ndhI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4,Fer4_7 CMS3_k127_7367384_4 1288963.ADIS_2413 1.047e-81 279.0 2DBAQ@1|root,2Z848@2|Bacteria,4NFR9@976|Bacteroidetes,47N8C@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7367384_5 1237149.C900_01483 2.059e-36 145.0 COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,47RR5@768503|Cytophagia 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_7367384_0 760192.Halhy_1895 4.279e-274 855.0 COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Heparinase II III-like protein - - - - - - - - - - - - DUF4962,Hepar_II_III CMS3_k127_7367384_2 1237149.C900_03794 3.889e-91 314.0 COG1914@1|root,COG1914@2|Bacteria,4NEG8@976|Bacteroidetes,47TDM@768503|Cytophagia 976|Bacteroidetes P Mn2 and Fe2 transporters of the NRAMP family - - - - - - - - - - - - Nramp CMS3_k127_7367384_1 240016.ABIZ01000001_gene5464 3.162e-191 608.0 COG3119@1|root,COG3119@2|Bacteria,46TXU@74201|Verrucomicrobia,2IV3I@203494|Verrucomicrobiae 2|Bacteria CP Sulfatase - - - - - - - - - - - - Sulfatase CMS3_k127_7367384_3 1123248.KB893317_gene4292 5.804e-83 286.0 COG0613@1|root,COG0613@2|Bacteria,4PN3D@976|Bacteroidetes 976|Bacteroidetes S PHP domain protein - - - - - - - - - - - - - CMS3_k127_7377255_1 1121904.ARBP01000017_gene5156 8.816e-185 586.0 COG0823@1|root,COG0823@2|Bacteria,4NQ0C@976|Bacteroidetes,47PP7@768503|Cytophagia 976|Bacteroidetes U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - CMS3_k127_7377255_0 1121904.ARBP01000009_gene4249 1.71e-214 673.0 COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia 976|Bacteroidetes M mandelate racemase muconate lactonizing - - 4.2.1.8 ko:K08323 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_7377255_2 1121930.AQXG01000001_gene1102 6.774e-163 539.0 COG2091@1|root,COG2091@2|Bacteria,4NGXG@976|Bacteroidetes 976|Bacteroidetes H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - CBM9_1 CMS3_k127_7377255_3 44251.PDUR_02750 7.911e-64 223.0 COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,4HEWY@91061|Bacilli,26USQ@186822|Paenibacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS3_k127_7380738_2 1123228.AUIH01000028_gene471 4.351e-06 57.0 29W44@1|root,30HNZ@2|Bacteria,1P948@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS3_k127_7380738_0 1121904.ARBP01000017_gene5079 9.152e-281 869.0 COG3507@1|root,COG3507@2|Bacteria,4NGA5@976|Bacteroidetes,47K5U@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 43 family - GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0046556,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 CMS3_k127_7380738_1 1237149.C900_04718 5.954e-23 110.0 COG2353@1|root,COG2353@2|Bacteria,4PP17@976|Bacteroidetes,47YSH@768503|Cytophagia 976|Bacteroidetes G YceI-like domain - - - - - - - - - - - - - CMS3_k127_739243_0 882083.SacmaDRAFT_1930 9.9e-151 487.0 COG2516@1|root,COG2516@2|Bacteria,2H2JZ@201174|Actinobacteria 201174|Actinobacteria S Elongator protein 3, MiaB family, Radical SAM - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM CMS3_k127_739243_2 882083.SacmaDRAFT_1929 8.826e-69 247.0 COG0095@1|root,COG0095@2|Bacteria,2HW3P@201174|Actinobacteria,4ECVC@85010|Pseudonocardiales 201174|Actinobacteria H Lipoate-protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB CMS3_k127_739243_1 882083.SacmaDRAFT_1928 9.714e-113 372.0 COG1856@1|root,COG1856@2|Bacteria,2H3RG@201174|Actinobacteria 201174|Actinobacteria S Elongator protein 3, MiaB family, Radical SAM - - - ko:K09711 - - - - ko00000 - - - Radical_SAM CMS3_k127_739243_4 994479.GL877878_gene78 2.405e-17 87.0 COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4E3RI@85010|Pseudonocardiales 201174|Actinobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H CMS3_k127_739243_3 882083.SacmaDRAFT_1925 1.906e-43 159.0 COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4DYWI@85010|Pseudonocardiales 201174|Actinobacteria C Fe-S oxidoreductase - - - - - - - - - - - - CCG,Fer4_9 CMS3_k127_7401640_1 388413.ALPR1_14849 2.695e-283 887.0 COG1529@1|root,COG1529@2|Bacteria,4NFFU@976|Bacteroidetes,47M68@768503|Cytophagia 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_7401640_2 1185876.BN8_03976 1.752e-119 393.0 COG1082@1|root,COG1082@2|Bacteria,4NIDT@976|Bacteroidetes,47JR4@768503|Cytophagia 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_7401640_0 1121875.KB907546_gene2712 7.858e-295 928.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NEZ5@976|Bacteroidetes,1HYTD@117743|Flavobacteriia 976|Bacteroidetes C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS3_k127_7401640_3 1121904.ARBP01000012_gene1387 1.123e-60 213.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,47JHZ@768503|Cytophagia 976|Bacteroidetes G Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis - - - - - - - - - - - - PFK CMS3_k127_7408338_5 755732.Fluta_2038 7.493e-59 217.0 COG2849@1|root,COG2849@2|Bacteria,4NW92@976|Bacteroidetes,1IKDQ@117743|Flavobacteriia,2PAPB@246874|Cryomorphaceae 976|Bacteroidetes S repeat protein - - - - - - - - - - - - - CMS3_k127_7408338_6 616991.JPOO01000001_gene4310 6.864e-50 181.0 COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,1I340@117743|Flavobacteriia,23HEW@178469|Arenibacter 976|Bacteroidetes E Stress responsive A/B Barrel Domain - - - - - - - - - - - - Dabb CMS3_k127_7408338_0 929562.Emtol_3283 1.753e-253 806.0 COG1629@1|root,COG1629@2|Bacteria,4PKVH@976|Bacteroidetes,47K3W@768503|Cytophagia 976|Bacteroidetes P PFAM TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,Plug CMS3_k127_7408338_7 1392490.JHZX01000001_gene3302 3.377e-47 192.0 COG0265@1|root,COG1572@1|root,COG3291@1|root,COG0265@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,4NIM1@976|Bacteroidetes,1I0WD@117743|Flavobacteriia 976|Bacteroidetes E Pregnancy-associated plasma protein-A - - - - - - - - - - - - MAM,PKD,Peptidase_M43,Reprolysin_3 CMS3_k127_7408338_3 760192.Halhy_1186 1.088e-123 409.0 COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IVTA@117747|Sphingobacteriia 976|Bacteroidetes S COGs COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - 3.5.1.32 ko:K01436,ko:K01451 ko00360,map00360 - R01424 RC00096,RC00162 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS3_k127_7408338_1 1237149.C900_04121 4.122e-207 671.0 COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,47JGS@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug CMS3_k127_7408338_2 1121904.ARBP01000012_gene1210 2.833e-188 598.0 COG0531@1|root,COG0531@2|Bacteria,4NH3Q@976|Bacteroidetes,47JXZ@768503|Cytophagia 976|Bacteroidetes E Amino acid permease eutP - - ko:K16238 - - - - ko00000,ko02000 2.A.3.5 - - AA_permease_2 CMS3_k127_7408338_4 760192.Halhy_0311 2.169e-74 254.0 COG0745@1|root,COG0745@2|Bacteria,4NGNK@976|Bacteroidetes,1ISG6@117747|Sphingobacteriia 976|Bacteroidetes K Two component transcriptional regulator, winged helix family - - - - - - - - - - - - Response_reg,Trans_reg_C CMS3_k127_7409786_0 1121904.ARBP01000009_gene4357 3.146e-307 969.0 COG2010@1|root,COG2010@2|Bacteria,4NEPV@976|Bacteroidetes,47JYA@768503|Cytophagia 2|Bacteria C Planctomycete cytochrome C - - - - - - - - - - - - PSCyt1,PSCyt2,PSD1 CMS3_k127_7409786_1 1121904.ARBP01000009_gene4358 4.474e-42 158.0 COG4102@1|root,COG4102@2|Bacteria,4NE73@976|Bacteroidetes,47KYW@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_741204_2 153721.MYP_2625 2.665e-98 333.0 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NEK7@976|Bacteroidetes,47MJ9@768503|Cytophagia 976|Bacteroidetes L PFAM Type III restriction enzyme, res subunit - - - - - - - - - - - - AAA_11,AAA_12 CMS3_k127_741204_1 1121481.AUAS01000007_gene932 3.844e-141 457.0 COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,47MD9@768503|Cytophagia 976|Bacteroidetes O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CMS3_k127_741204_5 1123277.KB893192_gene4334 2.722e-37 148.0 COG0576@1|root,COG0576@2|Bacteria,4NQ6M@976|Bacteroidetes,47QCT@768503|Cytophagia 976|Bacteroidetes O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE CMS3_k127_741204_3 1042376.AFPK01000028_gene2043 5.946e-39 152.0 COG2143@1|root,COG2143@2|Bacteria,4NM6B@976|Bacteroidetes,1I16Q@117743|Flavobacteriia,406JJ@61432|unclassified Flavobacteriaceae 976|Bacteroidetes O Protein of unknown function, DUF255 - - - - - - - - - - - - Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7 CMS3_k127_741204_0 925409.KI911562_gene592 7.155e-199 627.0 COG0766@1|root,COG0766@2|Bacteria,4NDV8@976|Bacteroidetes,1IPZR@117747|Sphingobacteriia 976|Bacteroidetes M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase CMS3_k127_741204_4 1123234.AUKI01000011_gene1334 1.579e-38 151.0 28H5J@1|root,2Z7I5@2|Bacteria,4NHK6@976|Bacteroidetes,1HXIU@117743|Flavobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4290) - - - - - - - - - - - - DUF4290 CMS3_k127_7426289_1 1443665.JACA01000056_gene3226 1.473e-99 330.0 COG3396@1|root,COG3396@2|Bacteria,4NFIT@976|Bacteroidetes,1I05P@117743|Flavobacteriia,2YIJB@290174|Aquimarina 976|Bacteroidetes S Phenylacetic acid catabolic protein paaC - 1.14.13.149 ko:K02611 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001,ko01000 - - - PaaA_PaaC CMS3_k127_7426289_2 1313421.JHBV01000003_gene602 6.91e-63 219.0 COG2151@1|root,COG2151@2|Bacteria,4NMS0@976|Bacteroidetes,1IXUP@117747|Sphingobacteriia 976|Bacteroidetes L Pfam:DUF59 paaD - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P CMS3_k127_7426289_0 1122226.AUHX01000003_gene91 7.877e-107 351.0 COG1024@1|root,COG1024@2|Bacteria,4NHRF@976|Bacteroidetes,1HXUI@117743|Flavobacteriia 976|Bacteroidetes I Belongs to the enoyl-CoA hydratase isomerase family - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 CMS3_k127_7434823_1 880071.Fleli_2541 6.667e-25 117.0 COG2425@1|root,COG2425@2|Bacteria,4NJ1T@976|Bacteroidetes 976|Bacteroidetes S protein containing a von Willebrand factor type A (vWA) domain - - - - - - - - - - - - VWA_2,VWA_CoxE CMS3_k127_7434823_0 880071.Fleli_2814 1.435e-120 405.0 COG0714@1|root,COG0714@2|Bacteria,4NIHC@976|Bacteroidetes,47KVE@768503|Cytophagia 976|Bacteroidetes S ATPase family associated with various cellular activities (AAA) ravA_1 - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_5 CMS3_k127_7437311_0 309801.trd_0142 3.271e-101 341.0 COG0095@1|root,COG0095@2|Bacteria 2|Bacteria H Lipoate-protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C CMS3_k127_7437311_1 194439.CT0861 1.595e-76 259.0 COG2210@1|root,COG2210@2|Bacteria,1FE9Q@1090|Chlorobi 1090|Chlorobi S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 CMS3_k127_7437311_4 1162668.LFE_2379 2.249e-21 95.0 COG0425@1|root,COG0425@2|Bacteria,3J1C1@40117|Nitrospirae 40117|Nitrospirae O Sulfurtransferase TusA - - - - - - - - - - - - TusA CMS3_k127_7437311_3 1122176.KB903541_gene190 1.073e-51 191.0 COG3258@1|root,COG3258@2|Bacteria,4PMKG@976|Bacteroidetes 976|Bacteroidetes C Protein of unknown function (DUF3365) - - - - - - - - - - - - DUF3365 CMS3_k127_7437311_2 523850.TON_1144 1.566e-56 206.0 COG4902@1|root,arCOG03957@2157|Archaea,2XX05@28890|Euryarchaeota,243QP@183968|Thermococci 183968|Thermococci S Uncharacterized protein domain (DUF2202) - - - - - - - - - - - - DUF2202 CMS3_k127_7442809_3 1279009.ADICEAN_01189 1.356e-65 230.0 COG2896@1|root,COG2896@2|Bacteria,4NFS9@976|Bacteroidetes,47K8J@768503|Cytophagia 976|Bacteroidetes H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22,4.6.1.17 ko:K03639,ko:K20967 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394,R11372 RC03420,RC03425 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM CMS3_k127_7442809_6 1279009.ADICEAN_01928 3.208e-38 148.0 COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,47RNG@768503|Cytophagia 976|Bacteroidetes K Transcriptional regulator - - - - - - - - - - - - Rrf2 CMS3_k127_7442809_0 1121904.ARBP01000006_gene3876 6.892e-151 492.0 COG0642@1|root,COG2205@2|Bacteria,4NGAS@976|Bacteroidetes,47PB2@768503|Cytophagia 976|Bacteroidetes T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA,TPR_8 CMS3_k127_7442809_1 1121904.ARBP01000006_gene3875 1.254e-108 355.0 COG0745@1|root,COG0745@2|Bacteria,4NIQC@976|Bacteroidetes,47PDQ@768503|Cytophagia 976|Bacteroidetes T Transcriptional regulatory protein, C terminal - - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS3_k127_7442809_2 313606.M23134_01907 3.138e-79 277.0 COG0793@1|root,COG0793@2|Bacteria,4NM82@976|Bacteroidetes,47PRW@768503|Cytophagia 976|Bacteroidetes M N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - - - - - - - - - - Peptidase_S41,Peptidase_S41_N,TPR_2 CMS3_k127_7442809_8 1122176.KB903542_gene399 1.41e-22 113.0 COG3391@1|root,COG3391@2|Bacteria,4NZAU@976|Bacteroidetes 976|Bacteroidetes DZ YceI-like domain - - - - - - - - - - - - - CMS3_k127_7442809_9 1122179.KB890441_gene1065 1.104e-11 78.0 COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1IS57@117747|Sphingobacteriia 976|Bacteroidetes S C-terminal domain of CHU protein family - - - - - - - - - - - - CHU_C CMS3_k127_7442809_10 1549858.MC45_13430 2.667e-09 67.0 COG3595@1|root,COG3595@2|Bacteria,1N374@1224|Proteobacteria,2UDAB@28211|Alphaproteobacteria,2K1A2@204457|Sphingomonadales 204457|Sphingomonadales S Putative auto-transporter adhesin, head GIN domain - - - - - - - - - - - - DUF2807 CMS3_k127_7442809_4 1288963.ADIS_0798 3.363e-51 194.0 COG3078@1|root,COG3078@2|Bacteria,4NIGK@976|Bacteroidetes,47K8U@768503|Cytophagia 976|Bacteroidetes P GTPase activator activity - - - - - - - - - - - - CarbopepD_reg_2 CMS3_k127_7442809_5 761193.Runsl_2080 1.579e-38 151.0 COG1595@1|root,COG1595@2|Bacteria,4NNBY@976|Bacteroidetes,47PH5@768503|Cytophagia 976|Bacteroidetes K RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_7442809_7 1121481.AUAS01000001_gene4549 1.788e-28 127.0 COG3712@1|root,COG3712@2|Bacteria,4NMA2@976|Bacteroidetes,47PEK@768503|Cytophagia 976|Bacteroidetes PT Domain of unknown function (DUF4974) - - - - - - - - - - - - DUF4974,FecR CMS3_k127_7449764_0 1453500.AT05_09355 1.855e-125 412.0 28KE7@1|root,2ZA0G@2|Bacteria,4P0D4@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7449764_1 1453500.AT05_09360 9.097e-105 368.0 COG2374@1|root,COG2374@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - CBM_3,Exo_endo_phos,LTD CMS3_k127_7449764_2 1453500.AT05_09365 1.237e-23 104.0 COG3209@1|root,COG3209@2|Bacteria,4P5ZD@976|Bacteroidetes 976|Bacteroidetes M COG3209 Rhs family protein - - - - - - - - - - - - - CMS3_k127_7467998_0 1122176.KB903552_gene3699 4.316e-72 252.0 COG1876@1|root,COG1876@2|Bacteria,4NFA4@976|Bacteroidetes 976|Bacteroidetes M D-alanyl-D-alanine carboxypeptidase vanY - - - - - - - - - - - VanY CMS3_k127_7467998_1 313606.M23134_02236 7.701e-22 100.0 COG1520@1|root,COG1520@2|Bacteria,4NJZY@976|Bacteroidetes,47TAC@768503|Cytophagia 976|Bacteroidetes M WD40-like Beta Propeller Repeat - - - - - - - - - - - - PD40 CMS3_k127_7472622_8 1078085.HMPREF1210_01981 1.454e-11 68.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,26EQ5@186818|Planococcaceae 91061|Bacilli S Belongs to the SOS response-associated peptidase family yoqW - - - - - - - - - - - SRAP CMS3_k127_7472622_6 998674.ATTE01000001_gene3400 1.292e-31 128.0 COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF3179) - - - - - - - - - - - - DUF3179 CMS3_k127_7472622_4 866895.HBHAL_2440 7.027e-54 197.0 COG1011@1|root,COG1011@2|Bacteria,1TQYM@1239|Firmicutes,4HFDW@91061|Bacilli,3NG99@45667|Halobacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 CMS3_k127_7472622_5 760192.Halhy_5291 9.757e-40 154.0 COG3427@1|root,COG3427@2|Bacteria,4NRMQ@976|Bacteroidetes,1IYK2@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Carbon monoxide dehydrogenase subunit G (CoxG) - - - ko:K09386 - - - - ko00000 - - - COXG CMS3_k127_7472622_3 309801.trd_1206 4.431e-74 252.0 COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,27XMB@189775|Thermomicrobia 189775|Thermomicrobia C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 CMS3_k127_7472622_0 518766.Rmar_0529 0.0 1115.0 COG1529@1|root,COG1529@2|Bacteria,4NFF5@976|Bacteroidetes 976|Bacteroidetes C Aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - 1.17.1.4,1.2.5.3 ko:K03520,ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS3_k127_7472622_2 760192.Halhy_2825 2.688e-101 337.0 COG1319@1|root,COG1319@2|Bacteria,4NE3W@976|Bacteroidetes,1IUZ3@117747|Sphingobacteriia 976|Bacteroidetes C COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS3_k127_7472622_7 1122179.KB890415_gene1999 8.415e-13 81.0 COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NYN2@976|Bacteroidetes,1IXQ8@117747|Sphingobacteriia 976|Bacteroidetes G Reprolysin (M12B) family zinc metalloprotease - - - - - - - - - - - - PKD,Reprolysin_5 CMS3_k127_7472622_1 984262.SGRA_4042 1.808e-151 498.0 COG3291@1|root,COG3291@2|Bacteria,4NG09@976|Bacteroidetes,1J102@117747|Sphingobacteriia 976|Bacteroidetes S Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,PKD,Peptidase_M36 CMS3_k127_7486618_8 1121104.AQXH01000001_gene1340 3.473e-11 63.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C CMS3_k127_7486618_6 468059.AUHA01000002_gene372 2.55e-34 137.0 COG0711@1|root,COG0711@2|Bacteria,4NQKA@976|Bacteroidetes,1ISAN@117747|Sphingobacteriia 976|Bacteroidetes C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B CMS3_k127_7486618_7 926549.KI421517_gene2267 4.911e-30 125.0 COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,47QGS@768503|Cytophagia 976|Bacteroidetes C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP CMS3_k127_7486618_2 1279009.ADICEAN_03047 8.35e-258 802.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,47JFI@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N CMS3_k127_7486618_5 471854.Dfer_4631 4.145e-84 288.0 COG0224@1|root,COG0224@2|Bacteria,4NECM@976|Bacteroidetes,47JM0@768503|Cytophagia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt CMS3_k127_7486618_1 1122176.KB903533_gene2320 0.0 1070.0 COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1IWMF@117747|Sphingobacteriia 976|Bacteroidetes P haloacid dehalogenase-like hydrolase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase CMS3_k127_7486618_9 880070.Cycma_4601 1.025e-08 61.0 2DSGB@1|root,33G1A@2|Bacteria,4NZ4A@976|Bacteroidetes,47V5I@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7486618_0 1408473.JHXO01000013_gene608 0.0 1772.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2G0EK@200643|Bacteroidia 976|Bacteroidetes V AcrB/AcrD/AcrF family cusA - - ko:K07787 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4 - - ACR_tran CMS3_k127_7486618_4 1408473.JHXO01000013_gene609 1.127e-107 367.0 COG1538@1|root,COG1538@2|Bacteria,4NDXW@976|Bacteroidetes,2FN4C@200643|Bacteroidia 976|Bacteroidetes MU Outer membrane efflux protein - - - - - - - - - - - - OEP CMS3_k127_7486618_3 869213.JCM21142_93990 1.233e-108 359.0 COG0845@1|root,COG2608@1|root,COG0845@2|Bacteria,COG2608@2|Bacteria,4NG8S@976|Bacteroidetes,47K97@768503|Cytophagia 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family cusB - - ko:K07798,ko:K15727 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.6.1.4,8.A.1,8.A.1.2.1 - - DUF3347,HlyD_D23,HlyD_D4 CMS3_k127_7488730_1 1434325.AZQN01000004_gene1687 4.287e-83 279.0 COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,47JSG@768503|Cytophagia 976|Bacteroidetes O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small CMS3_k127_7488730_4 1348583.ATLH01000002_gene726 5.608e-39 150.0 COG0295@1|root,COG0295@2|Bacteria,4NQED@976|Bacteroidetes,1I1A3@117743|Flavobacteriia,1F9AI@104264|Cellulophaga 976|Bacteroidetes F cytidine and deoxycytidylate deaminase cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 CMS3_k127_7488730_2 1408473.JHXO01000013_gene528 5.17e-69 245.0 28HA8@1|root,2Z7MQ@2|Bacteria,4NEJD@976|Bacteroidetes,2FP92@200643|Bacteroidia 976|Bacteroidetes S Domain of unknown function (DUF4835) - - - - - - - - - - - - DUF4835 CMS3_k127_7488730_0 1122621.ATZA01000004_gene1163 6.746e-124 408.0 COG0452@1|root,COG0452@2|Bacteria,4NE46@976|Bacteroidetes,1IPJR@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein CMS3_k127_7488730_5 743722.Sph21_1763 5.867e-26 109.0 2CT4B@1|root,32SSJ@2|Bacteria,4NQ76@976|Bacteroidetes,1ISVJ@117747|Sphingobacteriia 976|Bacteroidetes K RNA polymerase rpoZ - - - - - - - - - - - RNA_pol_Rpb6 CMS3_k127_7488730_3 468059.AUHA01000008_gene2728 1.781e-51 191.0 COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia 976|Bacteroidetes S outer membrane assembly lipoprotein YfiO yfiO - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - YfiO CMS3_k127_749578_1 313606.M23134_02255 6.162e-49 183.0 COG1629@1|root,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,47XXA@768503|Cytophagia 976|Bacteroidetes P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_749578_0 1150600.ADIARSV_3791 1.135e-114 378.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1IPVP@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_7498239_3 143224.JQMD01000002_gene2023 1.797e-54 194.0 COG2220@1|root,COG2220@2|Bacteria,4NENZ@976|Bacteroidetes,1HWY9@117743|Flavobacteriia 976|Bacteroidetes S beta-lactamase - - - - - - - - - - - - Lactamase_B_2 CMS3_k127_7498239_2 880070.Cycma_1185 1.598e-76 261.0 COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,47M3V@768503|Cytophagia 976|Bacteroidetes S Bestrophin, RFP-TM, chloride channel - - - ko:K08994 - - - - ko00000,ko02000 1.A.46.2 - - Bestrophin CMS3_k127_7498239_1 1121904.ARBP01000007_gene2989 1.229e-192 607.0 COG1883@1|root,COG1883@2|Bacteria,4NGCN@976|Bacteroidetes 976|Bacteroidetes C sodium ion-translocating decarboxylase, beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta CMS3_k127_7498239_0 1121904.ARBP01000007_gene2990 6.378e-289 898.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4NEQV@976|Bacteroidetes 976|Bacteroidetes C COG5016 Pyruvate oxaloacetate carboxyltransferase - - 6.4.1.1 ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173,M00620 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_lipoyl,Biotin_lipoyl_2,HMGL-like,PYC_OADA CMS3_k127_750658_1 391587.KAOT1_15988 1.382e-44 166.0 COG1652@1|root,COG1652@2|Bacteria,4NMED@976|Bacteroidetes,1I1AU@117743|Flavobacteriia 976|Bacteroidetes S Lysin motif - - - - - - - - - - - - BON,LysM CMS3_k127_750658_0 1122179.KB890423_gene2317 8.68e-173 552.0 28HYV@1|root,2Z846@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_7509030_0 1237149.C900_04280 8.239e-100 329.0 COG0673@1|root,COG0673@2|Bacteria,4NE75@976|Bacteroidetes,47K0H@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, NAD-binding Rossmann fold gfo - 1.1.99.28 ko:K00118 - - - - ko00000,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_7509030_1 153721.MYP_3093 2.153e-96 321.0 COG3279@1|root,COG3279@2|Bacteria,4NFPV@976|Bacteroidetes,47PTI@768503|Cytophagia 976|Bacteroidetes T Response regulator of the LytR AlgR family - - - ko:K02477 - - - - ko00000,ko02022 - - - LytTR,Response_reg CMS3_k127_7509030_2 1122176.KB903554_gene3921 1.477e-86 299.0 COG4948@1|root,COG4948@2|Bacteria 2|Bacteria M carboxylic acid catabolic process - - 5.1.1.20,5.5.1.1 ko:K01856,ko:K19802 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R05300,R05390,R06989,R08116,R09229,R10938 RC00903,RC01038,RC01108,RC01321,RC01356,RC03309 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N CMS3_k127_7512892_1 517418.Ctha_2482 6.163e-120 392.0 COG0451@1|root,COG0451@2|Bacteria,1FDWT@1090|Chlorobi 1090|Chlorobi M short-chain dehydrogenase reductase SDR - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase CMS3_k127_7512892_0 143224.JQMD01000002_gene3409 1.4e-193 630.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,1HXKJ@117743|Flavobacteriia 976|Bacteroidetes DM protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz CMS3_k127_7512892_2 1121904.ARBP01000022_gene3462 3.069e-48 184.0 COG1596@1|root,COG1596@2|Bacteria,4NFXJ@976|Bacteroidetes,47VGP@768503|Cytophagia 976|Bacteroidetes M Polysaccharide biosynthesis/export protein - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB CMS3_k127_7516265_0 1121904.ARBP01000037_gene2057 0.0 1287.0 COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,47MPU@768503|Cytophagia 976|Bacteroidetes G glycoside hydrolase family 2 sugar binding - - - - - - - - - - - - Glyco_hydro_106 CMS3_k127_7517203_2 378806.STAUR_3987 4.373e-21 109.0 COG1595@1|root,COG1595@2|Bacteria,1N3JF@1224|Proteobacteria 1224|Proteobacteria K GxGYxY sequence motif in domain of unknown function N-terminal - - - - - - - - - - - - GxGYxYP_C,GxGYxYP_N CMS3_k127_7517203_0 382464.ABSI01000014_gene1450 1.107e-75 262.0 COG1606@1|root,COG1606@2|Bacteria,46VAE@74201|Verrucomicrobia,2IUM5@203494|Verrucomicrobiae 203494|Verrucomicrobiae L tRNA processing - - - ko:K06864 - - - - ko00000 - - - ATP_bind_3,NAD_synthase CMS3_k127_7517203_1 639282.DEFDS_0021 3.344e-55 200.0 COG1691@1|root,COG1691@2|Bacteria,2GFE6@200930|Deferribacteres 200930|Deferribacteres S AIR carboxylase - - - ko:K06898 - - - - ko00000 - - - AIRC CMS3_k127_7517203_3 382464.ABSI01000014_gene1443 7.719e-21 95.0 COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia,2IUEA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes larC - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 CMS3_k127_7517864_1 1313421.JHBV01000037_gene2908 3.749e-55 201.0 COG1404@1|root,COG3209@1|root,COG1404@2|Bacteria,COG3209@2|Bacteria,4NRQS@976|Bacteroidetes 976|Bacteroidetes M Beta-galactosidase - - - - - - - - - - - - Fibrinogen_C CMS3_k127_7517864_0 1123057.P872_17885 2.11e-189 602.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia 976|Bacteroidetes EU Dipeptidyl peptidase IV (DPP IV) N-terminal region dpp - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,Peptidase_S9 CMS3_k127_7539137_0 1121011.AUCB01000013_gene184 2.899e-190 602.0 COG2986@1|root,COG2986@2|Bacteria,4NE0D@976|Bacteroidetes,1HX2V@117743|Flavobacteriia,23FZK@178469|Arenibacter 976|Bacteroidetes E Aromatic amino acid lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic CMS3_k127_7539137_1 1121904.ARBP01000005_gene4787 3.684e-137 440.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,47K5S@768503|Cytophagia 976|Bacteroidetes E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N CMS3_k127_7540298_10 1122176.KB903569_gene3495 4.471e-11 70.0 COG2931@1|root,COG3291@1|root,COG3591@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3591@2|Bacteria,4NG2K@976|Bacteroidetes,1IY1U@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the peptidase S1B family - - 3.4.21.50 ko:K01337 - - - - ko00000,ko01000,ko01002 - - - P_proprotein,Trypsin_2 CMS3_k127_7540298_13 1121912.AUHD01000004_gene2174 0.0001034 49.0 2E695@1|root,330X7@2|Bacteria,4NVE0@976|Bacteroidetes,1I53C@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7540298_12 1408473.JHXO01000009_gene3366 3.982e-06 53.0 COG3027@1|root,COG3027@2|Bacteria,4NSA5@976|Bacteroidetes,2FUYF@200643|Bacteroidia 976|Bacteroidetes D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA CMS3_k127_7540298_0 1237149.C900_04994 7.487e-203 644.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,47KJE@768503|Cytophagia 976|Bacteroidetes S Endoribonuclease that initiates mRNA decay rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 CMS3_k127_7540298_1 760192.Halhy_0358 6.635e-177 570.0 COG2911@1|root,COG2911@2|Bacteria 2|Bacteria S protein secretion - - - - - - - - - - - - Big_3_2,CBM_3,CHU_C,Flg_new,He_PIG,VCBS CMS3_k127_7540298_11 388413.ALPR1_04298 9.582e-09 61.0 2D3S1@1|root,32TFH@2|Bacteria,4NUIB@976|Bacteroidetes,47VY3@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7540298_3 99598.Cal7507_3130 2.088e-93 324.0 COG3385@1|root,COG3385@2|Bacteria,1GBUK@1117|Cyanobacteria,1HK07@1161|Nostocales 1117|Cyanobacteria L SPTR Transposase - - - - - - - - - - - - DDE_Tnp_1,Dimer_Tnp_Tn5 CMS3_k127_7540298_8 305900.GV64_11420 6.706e-36 144.0 290RU@1|root,2ZNDZ@2|Bacteria,1P98B@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS3_k127_7540298_5 525373.HMPREF0766_13634 4.914e-57 202.0 COG1764@1|root,COG1764@2|Bacteria,4NNF7@976|Bacteroidetes,1IT50@117747|Sphingobacteriia 976|Bacteroidetes O OsmC-like protein - - - - - - - - - - - - OsmC CMS3_k127_7540298_7 203124.Tery_2058 3.546e-49 189.0 COG4249@1|root,COG4249@2|Bacteria,1G0ZN@1117|Cyanobacteria,1HAZ6@1150|Oscillatoriales 1117|Cyanobacteria S Caspase domain - - - - - - - - - - - - Peptidase_C14 CMS3_k127_7540298_6 518766.Rmar_2771 8.046e-52 189.0 COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes 976|Bacteroidetes S MobA-related protein - - 2.7.7.76 ko:K07141 ko00790,map00790 - R11582 - ko00000,ko00001,ko01000 - - - NTP_transf_3 CMS3_k127_7540298_2 313606.M23134_05195 2.684e-140 454.0 COG4447@1|root,COG4447@2|Bacteria,4NKUX@976|Bacteroidetes,47U4I@768503|Cytophagia 976|Bacteroidetes S cellulose binding - - - - - - - - - - - - - CMS3_k127_7540298_9 1121904.ARBP01000006_gene3726 1.573e-31 126.0 COG1977@1|root,COG1977@2|Bacteria,4NVP9@976|Bacteroidetes,47VNX@768503|Cytophagia 976|Bacteroidetes H ThiS family - - - - - - - - - - - - ThiS CMS3_k127_7540298_4 1122179.KB890423_gene2354 2.859e-68 239.0 COG0062@1|root,COG0062@2|Bacteria,4P050@976|Bacteroidetes 976|Bacteroidetes G YjeF-related protein N-terminus - - - - - - - - - - - - YjeF_N CMS3_k127_7540298_14 398720.MED217_09350 0.0009263 49.0 COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,1HXAW@117743|Flavobacteriia,2XJX4@283735|Leeuwenhoekiella 976|Bacteroidetes T Tetratricopeptide repeat - - - - - - - - - - - - His_kinase,TPR_10,TPR_12,TPR_7,TPR_8 CMS3_k127_7543650_0 1408473.JHXO01000016_gene1926 1.109e-84 305.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NHCZ@976|Bacteroidetes,2G2X1@200643|Bacteroidia 976|Bacteroidetes S CHAT domain - - - - - - - - - - - - CHAT,TPR_12,TPR_7,TPR_8 CMS3_k127_7543650_1 1237149.C900_02937 2.034e-50 185.0 COG1262@1|root,COG1262@2|Bacteria,4NKVR@976|Bacteroidetes 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS3_k127_7543682_4 926549.KI421517_gene1212 3.85e-125 405.0 COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,47KBR@768503|Cytophagia 976|Bacteroidetes G Belongs to the ribulokinase family araB - 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N CMS3_k127_7543682_6 1121875.KB907550_gene657 4.841e-49 177.0 COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia 976|Bacteroidetes V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_7543682_0 1121904.ARBP01000024_gene6653 4.046e-309 959.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia 976|Bacteroidetes EU Peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_7543682_1 616991.JPOO01000001_gene2841 1.286e-228 719.0 COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia,23GVX@178469|Arenibacter 976|Bacteroidetes P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - DUF4976,Sulfatase CMS3_k127_7543682_3 1185876.BN8_01632 9.032e-185 587.0 COG0513@1|root,COG0513@2|Bacteria,4NHCA@976|Bacteroidetes,47MGW@768503|Cytophagia 976|Bacteroidetes L helicase superfamily c-terminal domain - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C CMS3_k127_7543682_2 504472.Slin_4717 6.874e-198 626.0 COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,47JH2@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_7543682_5 1268240.ATFI01000004_gene4002 1.311e-85 297.0 COG0738@1|root,COG0738@2|Bacteria,4NHZ7@976|Bacteroidetes,2FPGQ@200643|Bacteroidia,4AMIG@815|Bacteroidaceae 976|Bacteroidetes G Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - MFS_1,Sugar_tr CMS3_k127_7546961_3 411476.BACOVA_00550 2.366e-50 181.0 COG4430@1|root,COG4430@2|Bacteria,4NWI7@976|Bacteroidetes,2FN25@200643|Bacteroidia,4AN4M@815|Bacteroidaceae 976|Bacteroidetes S protein conserved in bacteria - - - - - - - - - - - - OmdA CMS3_k127_7546961_0 929562.Emtol_0993 1.115e-150 482.0 COG0332@1|root,COG0332@2|Bacteria,4NFIN@976|Bacteroidetes,47JAR@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS3_k127_7546961_1 926549.KI421517_gene197 3.277e-111 376.0 COG5276@1|root,COG5276@2|Bacteria,4NG4W@976|Bacteroidetes,47K9R@768503|Cytophagia 976|Bacteroidetes S LVIVD repeat - - - - - - - - - - - - LVIVD CMS3_k127_7546961_2 1121930.AQXG01000005_gene670 5.075e-60 214.0 COG0325@1|root,COG0325@2|Bacteria,4NE42@976|Bacteroidetes 976|Bacteroidetes S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N CMS3_k127_7557342_1 56107.Cylst_0149 3.085e-33 131.0 COG3744@1|root,COG3744@2|Bacteria,1G5PR@1117|Cyanobacteria,1HSI7@1161|Nostocales 1117|Cyanobacteria S PIN domain - - - - - - - - - - - - PIN CMS3_k127_7557342_5 459495.SPLC1_S520100 6.98e-06 50.0 2EAB0@1|root,334F8@2|Bacteria,1G8YS@1117|Cyanobacteria,1HDE5@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_7557342_3 163908.KB235896_gene3175 1.207e-15 79.0 COG2886@1|root,COG2886@2|Bacteria,1G7WF@1117|Cyanobacteria,1HSXH@1161|Nostocales 1117|Cyanobacteria S Uncharacterised protein family (UPF0175) - - - - - - - - - - - - UPF0175 CMS3_k127_7557342_0 317936.Nos7107_3288 4.675e-35 139.0 COG2405@1|root,COG2405@2|Bacteria,1G52J@1117|Cyanobacteria,1HPZ5@1161|Nostocales 1117|Cyanobacteria S Domain of unknown function (DUF3368) - - - ko:K07066 - - - - ko00000 - - - DUF3368 CMS3_k127_7557342_4 1282361.ABAC402_16315 1.095e-08 61.0 COG3668@1|root,COG3668@2|Bacteria 2|Bacteria D Plasmid stabilization system - - - - - - - - - - - - ParE_toxin CMS3_k127_7557342_2 1366050.N234_33695 4.216e-28 122.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae 28216|Betaproteobacteria T adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc CMS3_k127_7562738_1 344747.PM8797T_08389 8.317e-229 715.0 COG1520@1|root,COG1520@2|Bacteria,2IWVH@203682|Planctomycetes 203682|Planctomycetes S Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - - - - - - - - - - - CMS3_k127_7562738_0 616991.JPOO01000001_gene3009 5.632e-264 824.0 COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes,1HYQE@117743|Flavobacteriia,23GHM@178469|Arenibacter 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - Cytochrome_CBB3,GSDH CMS3_k127_7562738_2 1124780.ANNU01000079_gene2596 2.142e-16 79.0 COG1352@1|root,COG1352@2|Bacteria,4NNFZ@976|Bacteroidetes,47Q6K@768503|Cytophagia 976|Bacteroidetes NT Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_25 CMS3_k127_7565875_1 497964.CfE428DRAFT_6306 1.609e-62 220.0 COG1879@1|root,COG1879@2|Bacteria,46W7Q@74201|Verrucomicrobia 74201|Verrucomicrobia G PFAM periplasmic binding protein LacI transcriptional regulator - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 CMS3_k127_7565875_0 452471.Aasi_0854 7.438e-79 276.0 COG0790@1|root,COG0790@2|Bacteria,4NMCC@976|Bacteroidetes,47QS2@768503|Cytophagia 976|Bacteroidetes KLT Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Pkinase,Sel1,Tox-ODYAM1,U-box CMS3_k127_7565875_3 1191523.MROS_1659 2.165e-11 66.0 COG0432@1|root,COG0432@2|Bacteria 2|Bacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 CMS3_k127_7565875_2 762903.Pedsa_2641 5.33e-57 209.0 COG4122@1|root,COG4122@2|Bacteria,4NG1S@976|Bacteroidetes,1IRXU@117747|Sphingobacteriia 976|Bacteroidetes S Methyltransferase domain - - - - - - - - - - - - Methyltransf_24 CMS3_k127_7566506_3 1463855.JOHV01000001_gene1552 2.257e-35 141.0 COG1668@1|root,COG1668@2|Bacteria,2H8P2@201174|Actinobacteria 201174|Actinobacteria CP transmembrane transport - GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K16906 ko02010,map02010 M00224 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC2_membrane CMS3_k127_7566506_0 1209984.BN978_03118 2.935e-103 343.0 COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria,233EU@1762|Mycobacteriaceae 201174|Actinobacteria V ABC transporter - GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K16907 ko02010,map02010 M00224 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1 - - ABC_tran CMS3_k127_7566506_4 386415.NT01CX_1547 2.345e-27 119.0 COG1309@1|root,COG1309@2|Bacteria,1V8M2@1239|Firmicutes,24J7T@186801|Clostridia,36IZF@31979|Clostridiaceae 186801|Clostridia K Transcriptional regulator - - - - - - - - - - - - TetR_N CMS3_k127_7566506_2 1288963.ADIS_3943 4.967e-38 155.0 COG0589@1|root,COG0589@2|Bacteria,4NER9@976|Bacteroidetes,47PF0@768503|Cytophagia 976|Bacteroidetes T Universal stress protein - - - - - - - - - - - - Usp CMS3_k127_7566506_1 925409.KI911562_gene598 2.586e-98 329.0 COG0329@1|root,COG0329@2|Bacteria,4NHBA@976|Bacteroidetes,1IR29@117747|Sphingobacteriia 976|Bacteroidetes EM Belongs to the DapA family - - 4.1.3.3,4.2.1.41,4.3.3.7 ko:K01639,ko:K01707,ko:K01714 ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01811,R02279,R10147 RC00159,RC00600,RC00678,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS3_k127_7566506_5 1242864.D187_001420 1.41e-20 104.0 2FAP7@1|root,342WV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_7570166_3 1121875.KB907553_gene10 3.138e-06 50.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - Cyclase CMS3_k127_7570166_1 391603.FBALC1_16772 1.75e-53 214.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia 976|Bacteroidetes K COGs COG5616 integral membrane protein - - - - - - - - - - - - ANAPC3,Guanylate_cyc,HTH_18,TPR_8 CMS3_k127_7570166_0 1121875.KB907553_gene10 7.102e-106 349.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - Cyclase CMS3_k127_7579056_0 1121904.ARBP01000019_gene2783 0.0 1266.0 COG4888@1|root,COG4888@2|Bacteria,4NEE8@976|Bacteroidetes,47YC4@768503|Cytophagia 976|Bacteroidetes S ASPIC and UnbV - - - - - - - - - - - - UnbV_ASPIC,VCBS CMS3_k127_7579056_1 313603.FB2170_14288 1.428e-122 401.0 COG3419@1|root,COG3419@2|Bacteria,4NGV9@976|Bacteroidetes 976|Bacteroidetes NU Tfp pilus assembly protein tip-associated adhesin - - - - - - - - - - - - PQQ,PQQ_2 CMS3_k127_7586806_0 118173.KB235914_gene3829 4.643e-136 449.0 2DBP2@1|root,2ZA71@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS3_k127_7586806_1 1121904.ARBP01000013_gene349 6.276e-71 247.0 COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia 976|Bacteroidetes M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C,MR_MLE_N CMS3_k127_7591346_2 1124780.ANNU01000019_gene1749 1.398e-17 90.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,47KTD@768503|Cytophagia 976|Bacteroidetes O Trigger factor tig - - ko:K03545 - - - - ko00000 - - - Trigger_C,Trigger_N CMS3_k127_7591346_3 179408.Osc7112_1554 4.603e-06 51.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales 1117|Cyanobacteria T Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - ko:K19694 - - - - ko00000,ko01001,ko02022 - - - Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1 CMS3_k127_7591346_0 929556.Solca_2631 4.6e-313 977.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,1IQ4X@117747|Sphingobacteriia 976|Bacteroidetes C Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type pdhB - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C CMS3_k127_7591346_1 616991.JPOO01000001_gene4114 1.335e-107 351.0 COG3119@1|root,COG3119@2|Bacteria,4NGYE@976|Bacteroidetes,1I7XZ@117743|Flavobacteriia 976|Bacteroidetes P Protein of unknown function (DUF1501) - - - - - - - - - - - - DUF1501 CMS3_k127_7592117_1 1120968.AUBX01000017_gene1932 9.016e-298 921.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47JR2@768503|Cytophagia 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_7592117_0 1121904.ARBP01000022_gene3529 4.568e-311 959.0 2DBBU@1|root,2Z8AF@2|Bacteria,4NFUM@976|Bacteroidetes,47JIC@768503|Cytophagia 976|Bacteroidetes S SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD_RagB CMS3_k127_7592117_2 1121904.ARBP01000022_gene3520 1.146e-72 255.0 COG1621@1|root,COG1621@2|Bacteria,4PNCP@976|Bacteroidetes 976|Bacteroidetes G beta-fructofuranosidase activity - - - - - - - - - - - - - CMS3_k127_7592231_1 760192.Halhy_1218 6.157e-08 55.0 COG1672@1|root,COG1672@2|Bacteria,4NGWE@976|Bacteroidetes,1IR0Q@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Archaeal ATPase - - - ko:K06921 - - - - ko00000 - - - AAA_14,ATPase_2,DUF234 CMS3_k127_7592231_0 760192.Halhy_2973 1.211e-266 854.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_7592410_0 1122176.KB903554_gene3907 1.01e-160 515.0 COG3867@1|root,COG3867@2|Bacteria,4NI3G@976|Bacteroidetes,1IQD1@117747|Sphingobacteriia 976|Bacteroidetes G PFAM glycosyl hydrolase 53 - - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Glyco_hydro_53 CMS3_k127_7592410_1 411154.GFO_0033 1.196e-136 444.0 28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,1HX78@117743|Flavobacteriia 976|Bacteroidetes S SusE outer membrane protein - - - ko:K21571 - - - - ko00000 - - - SusE,SusF_SusE CMS3_k127_7594737_1 1392489.JPOL01000002_gene3274 7.48e-138 445.0 COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1I19J@117743|Flavobacteriia 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_7594737_0 694427.Palpr_1324 5.906e-140 456.0 COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,2FS76@200643|Bacteroidia,22XPD@171551|Porphyromonadaceae 976|Bacteroidetes M glycosyl transferase - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 CMS3_k127_7595693_4 1313301.AUGC01000008_gene403 6.944e-10 61.0 COG2353@1|root,COG2353@2|Bacteria,4NT3W@976|Bacteroidetes 976|Bacteroidetes S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_7595693_1 269798.CHU_3723 2.432e-73 263.0 COG2211@1|root,COG2211@2|Bacteria,4NJ9M@976|Bacteroidetes,47KGN@768503|Cytophagia 976|Bacteroidetes G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_7595693_0 518766.Rmar_0744 4.085e-155 524.0 COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FKAM@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes O Subtilase family - - - - - - - - - - - - Peptidase_S8 CMS3_k127_7595693_3 1120968.AUBX01000009_gene646 1.415e-12 77.0 COG2849@1|root,COG2849@2|Bacteria,4NUVT@976|Bacteroidetes,47XGD@768503|Cytophagia 976|Bacteroidetes S MORN repeat variant - - - - - - - - - - - - MORN_2 CMS3_k127_7595693_2 694427.Palpr_2533 2.002e-42 160.0 COG4232@1|root,COG4232@2|Bacteria,4NEW6@976|Bacteroidetes,2FNDE@200643|Bacteroidia,22WS5@171551|Porphyromonadaceae 976|Bacteroidetes CO Thiol disulfide interchange protein dsbD - 1.8.1.8 ko:K04084 - - - - ko00000,ko01000,ko03110 5.A.1.1 - - DsbC,DsbD,Thioredoxin_7 CMS3_k127_7600884_2 1454007.JAUG01000119_gene248 1.904e-71 243.0 COG0438@1|root,COG0438@2|Bacteria,4NFPA@976|Bacteroidetes,1IPP6@117747|Sphingobacteriia 976|Bacteroidetes M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 CMS3_k127_7600884_0 1121930.AQXG01000002_gene2019 1.549e-208 666.0 COG1009@1|root,COG1009@2|Bacteria,4NEBM@976|Bacteroidetes,1IQ9D@117747|Sphingobacteriia 976|Bacteroidetes CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N CMS3_k127_7600884_6 945713.IALB_1870 1.099e-26 112.0 COG0713@1|root,COG0713@2|Bacteria 2|Bacteria C ATP synthesis coupled electron transport nuoK GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 ko:K00340,ko:K05576 ko00190,ko01100,map00190,map01100 M00144,M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 CMS3_k127_7600884_5 517418.Ctha_1744 6.554e-34 136.0 COG0839@1|root,COG0839@2|Bacteria,1FF90@1090|Chlorobi 1090|Chlorobi C NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 CMS3_k127_7600884_3 1270196.JCKI01000004_gene1014 4.348e-71 249.0 COG1212@1|root,COG1212@2|Bacteria,4NG4B@976|Bacteroidetes,1IXQH@117747|Sphingobacteriia 976|Bacteroidetes M Cytidylyltransferase kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 CMS3_k127_7600884_1 313606.M23134_02235 9.035e-106 368.0 COG2885@1|root,COG2885@2|Bacteria 2|Bacteria M chlorophyll binding - - - - - - - - - - - - OmpA,PD40 CMS3_k127_7600884_4 1123277.KB893173_gene1827 8.8e-40 169.0 COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47JM8@768503|Cytophagia 976|Bacteroidetes S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - DUF3829,VWA,VWA_2 CMS3_k127_7603981_0 945713.IALB_0960 3.266e-172 554.0 COG1523@1|root,COG1523@2|Bacteria 2|Bacteria G belongs to the glycosyl hydrolase 13 family - - - - - - - - - - - - Alpha-amylase,CBM_48 CMS3_k127_7603981_2 1223410.KN050846_gene1482 2.193e-68 255.0 COG2304@1|root,COG2304@2|Bacteria,4NEGD@976|Bacteroidetes,1HY72@117743|Flavobacteriia 976|Bacteroidetes P von Willebrand factor, type A - - - - - - - - - - - - VWA CMS3_k127_7603981_5 485918.Cpin_1422 3.063e-11 73.0 2C2QD@1|root,33JG0@2|Bacteria,4PQ05@976|Bacteroidetes,1IZHI@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_7603981_4 883096.HMPREF9699_00068 8.781e-47 186.0 COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,1HYG0@117743|Flavobacteriia 976|Bacteroidetes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PEGA CMS3_k127_7603981_3 620914.JH621252_gene2562 2.838e-48 175.0 COG3254@1|root,COG3254@2|Bacteria,4NQAA@976|Bacteroidetes,1I46Z@117743|Flavobacteriia 976|Bacteroidetes S L-rhamnose mutarotase - - 5.1.3.32 ko:K03534 - - R10819 RC00563 ko00000,ko01000 - - - rhaM CMS3_k127_7603981_1 314230.DSM3645_13780 1.038e-87 300.0 COG0657@1|root,COG0657@2|Bacteria,2IYY7@203682|Planctomycetes 203682|Planctomycetes I Carboxylesterase family - - - - - - - - - - - - Abhydrolase_3 CMS3_k127_7603981_6 1122925.KB895377_gene1221 2.533e-05 48.0 COG2006@1|root,COG2006@2|Bacteria,1UMYS@1239|Firmicutes,4IU3I@91061|Bacilli,26YEM@186822|Paenibacillaceae 91061|Bacilli S Carbohydrate family 9 binding domain-like - - - - - - - - - - - - CBM9_1 CMS3_k127_7608855_1 1122179.KB890438_gene1532 2.215e-83 278.0 COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1IXIF@117747|Sphingobacteriia 976|Bacteroidetes IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C CMS3_k127_7608855_0 509635.N824_10775 0.0 1035.0 COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1IP7K@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - - - - - - - - - - - CHB_HEX_C_1,DUF4982,Fn3_assoc,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N CMS3_k127_7608855_2 715451.ambt_19150 8.055e-05 46.0 COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,1RNY4@1236|Gammaproteobacteria,464EY@72275|Alteromonadaceae 1236|Gammaproteobacteria P alkaline phosphatase phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N CMS3_k127_761507_4 1185876.BN8_03356 1.188e-69 264.0 COG4249@1|root,COG4249@2|Bacteria 2|Bacteria S B-1 B cell differentiation - - - - - - - - - - - - Lipase_GDSL_2,Peptidase_C14,Trypsin_2 CMS3_k127_761507_6 1122179.KB890446_gene380 1.018e-54 216.0 COG4249@1|root,COG4249@2|Bacteria,4NKV1@976|Bacteroidetes,1IXN5@117747|Sphingobacteriia 976|Bacteroidetes V Peptidase C14 caspase catalytic subunit p20 - - - - - - - - - - - - Peptidase_C14 CMS3_k127_761507_3 313606.M23134_06584 3.075e-96 325.0 COG1647@1|root,COG1647@2|Bacteria,4NHPY@976|Bacteroidetes,47JR1@768503|Cytophagia 976|Bacteroidetes E Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,BAAT_C,Hydrolase_4 CMS3_k127_761507_0 1122176.KB903531_gene3073 1.347e-147 512.0 COG2312@1|root,COG2312@2|Bacteria,4PP0J@976|Bacteroidetes 976|Bacteroidetes E CotH kinase protein - - - - - - - - - - - - CHB_HEX_C_1,CotH,LTD CMS3_k127_761507_7 573061.Clocel_1966 1.323e-39 171.0 COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae 186801|Clostridia S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos CMS3_k127_761507_8 880073.Calab_3522 8.329e-38 166.0 COG4447@1|root,COG4447@2|Bacteria,2NRC1@2323|unclassified Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - PSII_BNR CMS3_k127_761507_1 1123248.KB893320_gene3912 7.057e-136 447.0 COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,1IVKJ@117747|Sphingobacteriia 976|Bacteroidetes G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - 5.1.3.11 ko:K16213 - - R01445,R10810 RC00289 ko00000,ko01000 - - - GlcNAc_2-epim CMS3_k127_761507_2 382464.ABSI01000020_gene299 4.925e-109 360.0 COG3622@1|root,COG3622@2|Bacteria,46TIJ@74201|Verrucomicrobia,2IV0G@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_761507_5 985867.AEWF01000012_gene1288 3.459e-66 234.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,47EWD@766|Rickettsiales 28211|Alphaproteobacteria D involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 CMS3_k127_7623036_0 1122176.KB903576_gene5032 1.089e-107 374.0 COG2319@1|root,COG4995@1|root,COG2319@2|Bacteria,COG4995@2|Bacteria,4P49H@976|Bacteroidetes 976|Bacteroidetes H WD40 repeats - - - - - - - - - - - - CHAT CMS3_k127_7623036_1 903818.KI912268_gene725 0.0006192 51.0 COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria 57723|Acidobacteria S Domain of unknown function (DUF4178) - - - - - - - - - - - - DUF4178 CMS3_k127_762491_7 1519464.HY22_02905 1.777e-33 134.0 COG0527@1|root,COG0527@2|Bacteria,1FDBX@1090|Chlorobi 1090|Chlorobi E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase CMS3_k127_762491_3 1408813.AYMG01000009_gene3152 1.149e-98 336.0 COG0527@1|root,COG0527@2|Bacteria,4NF0M@976|Bacteroidetes,1IQ3C@117747|Sphingobacteriia 976|Bacteroidetes E Belongs to the aspartokinase family lysC - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase CMS3_k127_762491_2 313606.M23134_02135 3.284e-176 557.0 COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,47KF1@768503|Cytophagia 976|Bacteroidetes EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN CMS3_k127_762491_5 1121896.JMLU01000018_gene2865 4.087e-57 203.0 COG0440@1|root,COG0440@2|Bacteria,4NIDK@976|Bacteroidetes,1HZAW@117743|Flavobacteriia,2NUB5@237|Flavobacterium 976|Bacteroidetes E synthase small subunit - - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C CMS3_k127_762491_0 1121904.ARBP01000005_gene4654 3.872e-258 807.0 COG0028@1|root,COG0028@2|Bacteria,4NENG@976|Bacteroidetes,47KS8@768503|Cytophagia 976|Bacteroidetes EH TIGRFAM acetolactate synthase, large subunit, biosynthetic type ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS3_k127_762491_1 1121896.JMLU01000018_gene2867 1.205e-255 797.0 COG0129@1|root,COG0129@2|Bacteria,4NFHP@976|Bacteroidetes,1HX1X@117743|Flavobacteriia,2NU1S@237|Flavobacterium 976|Bacteroidetes E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD CMS3_k127_762491_4 1121904.ARBP01000005_gene4652 7.994e-84 287.0 COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes,47TWP@768503|Cytophagia 976|Bacteroidetes E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 CMS3_k127_762491_6 643867.Ftrac_2073 6.111e-56 199.0 COG1327@1|root,COG1327@2|Bacteria,4NHXI@976|Bacteroidetes,47P1Y@768503|Cytophagia 976|Bacteroidetes K PFAM ATP cone domain - - - - - - - - - - - - ATP-cone,Mrr_cat CMS3_k127_7625453_3 457424.BFAG_03190 3.895e-48 177.0 COG0841@1|root,COG0841@2|Bacteria,4NE3H@976|Bacteroidetes,2FN4H@200643|Bacteroidia,4AKMX@815|Bacteroidaceae 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS3_k127_7625453_2 435591.BDI_3436 1.39e-78 275.0 COG0845@1|root,COG0845@2|Bacteria,4NHJH@976|Bacteroidetes,2FP9C@200643|Bacteroidia,22VUH@171551|Porphyromonadaceae 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS3_k127_7625453_1 1095750.HMPREF9970_2844 2.274e-81 280.0 COG3646@1|root,COG3646@2|Bacteria,1UICZ@1239|Firmicutes,25EHY@186801|Clostridia,1HV2Y@1164882|Lachnoanaerobaculum 186801|Clostridia S KilA-N - - - - - - - - - - - - KilA-N CMS3_k127_7625453_0 1166018.FAES_4574 2.84e-159 517.0 COG2072@1|root,COG2072@2|Bacteria,4NKS6@976|Bacteroidetes,47MF8@768503|Cytophagia 976|Bacteroidetes P Flavin-binding monooxygenase-like hapE - - - - - - - - - - - FMO-like,K_oxygenase,NAD_binding_8,Pyr_redox_3 CMS3_k127_7625453_5 118161.KB235922_gene2598 6.211e-15 79.0 COG1669@1|root,COG1669@2|Bacteria,1G8U6@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 CMS3_k127_7625453_6 1392489.JPOL01000002_gene1010 1.68e-10 67.0 COG2361@1|root,COG2361@2|Bacteria,4NSC7@976|Bacteroidetes,1II6Z@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function DUF86 - - - - - - - - - - - - DUF86 CMS3_k127_7625453_4 1047013.AQSP01000140_gene2509 1.482e-19 91.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS3_k127_7633785_1 760192.Halhy_2973 1.119e-107 355.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_7633785_0 760192.Halhy_2051 4.923e-296 955.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria 2|Bacteria T PhoQ Sensor - - 4.6.1.1 ko:K01768,ko:K16923,ko:K19694 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00582,M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022 3.A.1.28 - - 7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_764740_0 745718.JADT01000001_gene1669 3.603e-74 267.0 COG2849@1|root,COG2849@2|Bacteria,4NJB4@976|Bacteroidetes,1I0QY@117743|Flavobacteriia 976|Bacteroidetes S Protein of unknown function (DUF3352) - - - - - - - - - - - - DUF3352,MORN_2 CMS3_k127_775370_0 929562.Emtol_0414 4.881e-285 888.0 COG4225@1|root,COG4225@2|Bacteria,4NG6C@976|Bacteroidetes,47J9H@768503|Cytophagia 976|Bacteroidetes S Heparinase II/III-like protein - - - - - - - - - - - - Hepar_II_III CMS3_k127_775370_2 926562.Oweho_2581 3.202e-55 201.0 2BNB7@1|root,32GYU@2|Bacteria,4NQDS@976|Bacteroidetes,1ICNB@117743|Flavobacteriia,2PB7H@246874|Cryomorphaceae 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_775370_1 1121875.KB907551_gene970 3.002e-150 479.0 COG1649@1|root,COG1649@2|Bacteria 2|Bacteria F PFAM Uncharacterised BCR, COG1649 - - - - - - - - - - - - GHL10,Polysacc_deac_1 CMS3_k127_790147_1 865938.Weevi_1467 3.622e-47 173.0 COG0566@1|root,COG0566@2|Bacteria,4NM8C@976|Bacteroidetes,1HY0Q@117743|Flavobacteriia 976|Bacteroidetes J Methyltransferase spoU - - - - - - - - - - - SpoU_methylase CMS3_k127_790147_2 1487953.JMKF01000037_gene3241 2.552e-41 171.0 COG1680@1|root,COG2931@1|root,COG1680@2|Bacteria,COG2931@2|Bacteria,1G5C3@1117|Cyanobacteria,1HAVU@1150|Oscillatoriales 1117|Cyanobacteria Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - HemolysinCabind CMS3_k127_790147_0 1122176.KB903555_gene3786 5.355e-117 384.0 COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1IR6K@117747|Sphingobacteriia 976|Bacteroidetes S protein (some members contain a von Willebrand factor type A (vWA) domain) - - - - - - - - - - - - DUF58 CMS3_k127_790147_3 1168034.FH5T_13680 1.692e-10 66.0 COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia 976|Bacteroidetes O Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - CMS3_k127_80594_2 1121007.AUML01000017_gene381 2.588e-14 80.0 COG1595@1|root,COG1595@2|Bacteria,4NTGC@976|Bacteroidetes,1I2AP@117743|Flavobacteriia,2YJC2@290174|Aquimarina 976|Bacteroidetes K Sigma-70 region 2 - - - - - - - - - - - - Sigma70_r2 CMS3_k127_80594_0 388413.ALPR1_16703 3.666e-189 597.0 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - - - - - - - - - - Metallophos CMS3_k127_80594_1 1121912.AUHD01000001_gene2741 2.187e-157 503.0 COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1HXVD@117743|Flavobacteriia 976|Bacteroidetes E peptidase M1 - - - - - - - - - - - - Peptidase_M1 CMS3_k127_811799_3 1122179.KB890423_gene2346 5.923e-143 464.0 COG1435@1|root,COG1435@2|Bacteria,4NE0S@976|Bacteroidetes,1IR0Y@117747|Sphingobacteriia 976|Bacteroidetes F RagB SusD domain protein - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_811799_0 1122179.KB890423_gene2345 1.274e-306 970.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1IPHV@117747|Sphingobacteriia 976|Bacteroidetes P CarboxypepD_reg-like domain - - - - - - - - - - - - CarbopepD_reg_2,Plug,STN,TonB_dep_Rec CMS3_k127_811799_2 1122179.KB890423_gene2325 1.428e-177 566.0 COG2610@1|root,COG2610@2|Bacteria,4NFQH@976|Bacteroidetes,1IQKX@117747|Sphingobacteriia 976|Bacteroidetes EG COGs COG2610 H gluconate symporter and related permease - - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease CMS3_k127_811799_1 1122179.KB890423_gene2348 3.02e-212 673.0 COG4625@1|root,COG4625@2|Bacteria,4PNWV@976|Bacteroidetes,1J0UR@117747|Sphingobacteriia 976|Bacteroidetes S Right handed beta helix region - - - - - - - - - - - - Beta_helix CMS3_k127_82093_0 143224.JQMD01000002_gene34 1.844e-146 467.0 COG1395@1|root,COG1395@2|Bacteria,4NHQT@976|Bacteroidetes,1IJAX@117743|Flavobacteriia 976|Bacteroidetes K SusD family - - - ko:K21572 - - - - ko00000,ko02000 8.A.46.1,8.A.46.3 - - SusD-like_3,SusD_RagB CMS3_k127_82093_1 938709.AUSH02000017_gene1072 4.897e-108 374.0 COG1629@1|root,COG4771@2|Bacteria,4NDX3@976|Bacteroidetes 976|Bacteroidetes P TonB-dependent Receptor Plug - - - - - - - - - - - - CarbopepD_reg_2,Plug,TonB_dep_Rec CMS3_k127_823683_6 926549.KI421517_gene3918 2.887e-72 258.0 COG0642@1|root,COG2205@2|Bacteria,4NEIS@976|Bacteroidetes,47MHI@768503|Cytophagia 976|Bacteroidetes T histidine kinase HAMP region domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA CMS3_k127_823683_3 1121904.ARBP01000006_gene3731 4.127e-195 623.0 COG0659@1|root,COG0659@2|Bacteria,4NE9G@976|Bacteroidetes,47MPC@768503|Cytophagia 976|Bacteroidetes P COGs COG0659 Sulfate permease and related transporter (MFS superfamily) - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - Sulfate_transp CMS3_k127_823683_8 1385521.N803_09700 6.794e-21 100.0 COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria 201174|Actinobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.11 ko:K03428 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R04237 RC00003,RC00460 ko00000,ko00001,ko01000 - - - Methyltransf_11,Methyltransf_25 CMS3_k127_823683_5 745718.JADT01000015_gene2852 3.694e-88 306.0 COG1538@1|root,COG1538@2|Bacteria,4NEMI@976|Bacteroidetes,1HYGI@117743|Flavobacteriia 976|Bacteroidetes MU PFAM Outer membrane efflux protein tolC - - - - - - - - - - - OEP CMS3_k127_823683_0 1122176.KB903546_gene996 5e-324 1025.0 COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia 976|Bacteroidetes V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran CMS3_k127_823683_4 1122176.KB903546_gene995 2.071e-90 310.0 COG0845@1|root,COG0845@2|Bacteria,4NF0X@976|Bacteroidetes 976|Bacteroidetes M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - HlyD_3 CMS3_k127_823683_7 313606.M23134_07637 7.541e-31 129.0 COG1846@1|root,COG1846@2|Bacteria,4NRHI@976|Bacteroidetes,47T3Y@768503|Cytophagia 976|Bacteroidetes K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - HTH_27,MarR CMS3_k127_823683_2 485918.Cpin_6279 1.634e-199 631.0 COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,1IPV2@117747|Sphingobacteriia 976|Bacteroidetes S protein conserved in bacteria (DUF2329) - - - - - - - - - - - - DUF3131,Glycoamylase CMS3_k127_823683_1 1237149.C900_04933 1.274e-231 727.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47JBR@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 3 family - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C CMS3_k127_82896_0 395493.BegalDRAFT_1582 7.187e-209 668.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,45ZNG@72273|Thiotrichales 72273|Thiotrichales H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses nadE - 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase CMS3_k127_82896_3 1279009.ADICEAN_00873 1.619e-85 289.0 COG1051@1|root,COG1051@2|Bacteria,4NH28@976|Bacteroidetes,47P8V@768503|Cytophagia 976|Bacteroidetes F Belongs to the Nudix hydrolase family - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX CMS3_k127_82896_2 1408433.JHXV01000005_gene2445 5.863e-100 340.0 COG0451@1|root,COG0451@2|Bacteria,4NKKZ@976|Bacteroidetes,1I74R@117743|Flavobacteriia 976|Bacteroidetes M Male sterility protein - - - - - - - - - - - - Epimerase CMS3_k127_82896_4 313606.M23134_00765 5.629e-75 260.0 COG0491@1|root,COG0491@2|Bacteria,4PJTF@976|Bacteroidetes,47QS6@768503|Cytophagia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS3_k127_82896_1 313606.M23134_00764 8.934e-120 398.0 COG1541@1|root,COG1541@2|Bacteria,4NGHR@976|Bacteroidetes,47MBK@768503|Cytophagia 976|Bacteroidetes H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - - - - - - - - - - - CMS3_k127_835148_0 1121904.ARBP01000004_gene807 6.931e-310 973.0 COG1640@1|root,COG1640@2|Bacteria,4NF7Z@976|Bacteroidetes,47NI0@768503|Cytophagia 976|Bacteroidetes G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - CBM_20,Glyco_hydro_77 CMS3_k127_835148_5 945713.IALB_1280 9.425e-15 90.0 COG2133@1|root,COG2133@2|Bacteria 2|Bacteria G pyrroloquinoline quinone binding - - 1.1.5.2 ko:K00117 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - GSDH,SGL CMS3_k127_835148_1 1313421.JHBV01000009_gene4113 1.969e-275 910.0 COG2132@1|root,COG3209@1|root,COG2132@2|Bacteria,COG3209@2|Bacteria,4PKBQ@976|Bacteroidetes 976|Bacteroidetes M SPTR CHU large protein - - - - - - - - - - - - CHU_C,SprB CMS3_k127_835148_4 714943.Mucpa_4487 1.031e-19 91.0 COG0355@1|root,COG0355@2|Bacteria,4NUYG@976|Bacteroidetes,1ITVV@117747|Sphingobacteriia 976|Bacteroidetes C ATP synthase atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N CMS3_k127_835148_2 984262.SGRA_1989 2.081e-236 739.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,1IPG7@117747|Sphingobacteriia 976|Bacteroidetes C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N CMS3_k127_835148_3 1237149.C900_02542 4.509e-55 200.0 COG1215@1|root,COG1215@2|Bacteria,4NMSY@976|Bacteroidetes,47NMB@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS3_k127_84206_2 1219035.NT2_09_01410 7.197e-29 123.0 COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,2U0WY@28211|Alphaproteobacteria,2K3BZ@204457|Sphingomonadales 204457|Sphingomonadales C Oxidoreductase FAD-binding domain - - 1.17.1.1 ko:K00523,ko:K02613 ko00360,ko00520,ko01120,map00360,map00520,map01120 - R03391,R03392,R09838 RC00230,RC02690 ko00000,ko00001,ko01000 - - - FAD_binding_6,Fer2,NAD_binding_1 CMS3_k127_84206_0 153721.MYP_2591 5.859e-160 510.0 COG0492@1|root,COG0492@2|Bacteria,4NEQM@976|Bacteroidetes,47KZW@768503|Cytophagia 976|Bacteroidetes C Ferredoxin--NADP reductase trxB2 - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS3_k127_84206_3 743722.Sph21_2968 3.809e-24 106.0 COG0633@1|root,COG0633@2|Bacteria,4NQ4P@976|Bacteroidetes,1IU16@117747|Sphingobacteriia 976|Bacteroidetes C 2Fe-2S iron-sulfur cluster binding domain thcC - - ko:K04755 - - - - ko00000 - - - Fer2 CMS3_k127_84206_1 468059.AUHA01000002_gene723 3.727e-96 318.0 COG2321@1|root,COG2321@2|Bacteria,4NDTZ@976|Bacteroidetes,1INUC@117747|Sphingobacteriia 976|Bacteroidetes S Neutral zinc metallopeptidase ypfJ - - ko:K07054 - - - - ko00000 - - - Zn_peptidase CMS3_k127_843635_0 1122176.KB903544_gene776 1.879e-218 690.0 COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1IS9Z@117747|Sphingobacteriia 976|Bacteroidetes E Sodium:alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp CMS3_k127_843635_1 616991.JPOO01000003_gene62 1.354e-97 327.0 COG2133@1|root,COG2133@2|Bacteria,4NG3Q@976|Bacteroidetes,1I7ZP@117743|Flavobacteriia 976|Bacteroidetes G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_861835_5 1122176.KB903576_gene5032 9.131e-69 246.0 COG2319@1|root,COG4995@1|root,COG2319@2|Bacteria,COG4995@2|Bacteria,4P49H@976|Bacteroidetes 976|Bacteroidetes H WD40 repeats - - - - - - - - - - - - CHAT CMS3_k127_861835_4 1267211.KI669560_gene610 1.156e-75 263.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - - - - - - - - - - - AP_endonuc_2 CMS3_k127_861835_3 1237149.C900_04518 1.146e-77 265.0 COG0225@1|root,COG0225@2|Bacteria,4NMAJ@976|Bacteroidetes,47N5N@768503|Cytophagia 976|Bacteroidetes O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA1 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR CMS3_k127_861835_2 616991.JPOO01000001_gene3067 1.137e-123 405.0 COG0673@1|root,COG0673@2|Bacteria,4PEWX@976|Bacteroidetes,1IFGP@117743|Flavobacteriia,23I4U@178469|Arenibacter 976|Bacteroidetes S Oxidoreductase family, C-terminal alpha/beta domain - - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS3_k127_861835_0 1121011.AUCB01000006_gene1107 1.111e-281 876.0 COG3962@1|root,COG3962@2|Bacteria,4PNK4@976|Bacteroidetes,1IK7S@117743|Flavobacteriia,23I0A@178469|Arenibacter 976|Bacteroidetes E Thiamine pyrophosphate enzyme, central domain - - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS3_k127_861835_1 1121481.AUAS01000005_gene2056 2.448e-126 407.0 COG3718@1|root,COG3718@2|Bacteria,4NKW4@976|Bacteroidetes,47TKD@768503|Cytophagia 976|Bacteroidetes G KduI/IolB family - - 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08503 RC00541 ko00000,ko00001,ko01000 - - - KduI CMS3_k127_865865_1 1137281.D778_02017 4.765e-35 140.0 2AFPW@1|root,315RN@2|Bacteria,4NFY9@976|Bacteroidetes,1I0KQ@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_865865_0 143224.JQMD01000002_gene3415 2.345e-62 223.0 COG0438@1|root,COG0438@2|Bacteria,4NGFN@976|Bacteroidetes 976|Bacteroidetes M Glycosyltransferase, group 1 family - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_86768_1 118161.KB235922_gene2880 2.017e-54 211.0 COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,3VHWS@52604|Pleurocapsales 1117|Cyanobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase CMS3_k127_86768_0 1341181.FLJC2902T_16530 1.579e-136 442.0 COG0635@1|root,COG0635@2|Bacteria,4NEY5@976|Bacteroidetes,1HYDQ@117743|Flavobacteriia,2NTPQ@237|Flavobacterium 976|Bacteroidetes H Belongs to the anaerobic coproporphyrinogen-III oxidase family hemN - - - - - - - - - - - HemN_C,Radical_SAM CMS3_k127_86872_0 1288963.ADIS_4554 3.594e-314 970.0 COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,47KIX@768503|Cytophagia 976|Bacteroidetes G Glycosyl hydrolase family 3 C-terminal domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,fn3 CMS3_k127_86872_2 468059.AUHA01000005_gene2452 3.935e-17 82.0 COG0477@1|root,COG2814@2|Bacteria,4NEN9@976|Bacteroidetes,1IR8C@117747|Sphingobacteriia 976|Bacteroidetes EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS3_k127_86872_1 1296416.JACB01000042_gene1780 6.608e-249 777.0 COG2304@1|root,COG3591@1|root,COG2304@2|Bacteria,COG3591@2|Bacteria 2|Bacteria E Belongs to the peptidase S1B family - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - Big_2,NB-ARC,PKD,PPC,Sel1,Trypsin,Trypsin_2,VWA,VWA_2 CMS3_k127_87151_3 385682.AFSL01000001_gene1998 2.598e-31 134.0 2CAAQ@1|root,331TU@2|Bacteria,4NTCJ@976|Bacteroidetes,2G24Y@200643|Bacteroidia,3XJU8@558415|Marinilabiliaceae 976|Bacteroidetes S O-antigen ligase like membrane protein - - - - - - - - - - - - Wzy_C CMS3_k127_87151_1 385682.AFSL01000001_gene1997 2.502e-78 274.0 COG0438@1|root,COG0438@2|Bacteria,4NJ1W@976|Bacteroidetes,2FTR3@200643|Bacteroidia,3XK2C@558415|Marinilabiliaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS3_k127_87151_0 880071.Fleli_1561 7.294e-185 598.0 COG0367@1|root,COG0367@2|Bacteria,4NFQ3@976|Bacteroidetes,47JSF@768503|Cytophagia 976|Bacteroidetes E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 CMS3_k127_87151_2 1168289.AJKI01000012_gene322 8.129e-42 160.0 COG0438@1|root,COG0438@2|Bacteria,4NMHA@976|Bacteroidetes,2FTK8@200643|Bacteroidia,3XK9W@558415|Marinilabiliaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 CMS3_k127_871878_4 1121904.ARBP01000007_gene2913 1.439e-46 172.0 2CNQU@1|root,32SHJ@2|Bacteria,4NSMZ@976|Bacteroidetes,47S3X@768503|Cytophagia 976|Bacteroidetes S DoxX family - - - - - - - - - - - - DoxX CMS3_k127_871878_5 1211035.CD30_11120 2.177e-31 128.0 COG0454@1|root,COG0456@2|Bacteria,1V562@1239|Firmicutes,4HMAE@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 CMS3_k127_871878_3 1121904.ARBP01000005_gene4463 7.237e-55 197.0 COG0314@1|root,COG0314@2|Bacteria,4NP1X@976|Bacteroidetes,47QJT@768503|Cytophagia 976|Bacteroidetes H Molybdopterin converting factor, large subunit moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE CMS3_k127_871878_6 761193.Runsl_5157 2.669e-19 90.0 COG1977@1|root,COG1977@2|Bacteria,4NUVK@976|Bacteroidetes,47RZY@768503|Cytophagia 976|Bacteroidetes H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS CMS3_k127_871878_1 1166018.FAES_3608 1.221e-73 257.0 COG1526@1|root,COG1526@2|Bacteria,4NFJB@976|Bacteroidetes,47MUW@768503|Cytophagia 976|Bacteroidetes C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ CMS3_k127_871878_0 485918.Cpin_4072 9.784e-144 467.0 COG0243@1|root,COG0243@2|Bacteria,4NF6W@976|Bacteroidetes,1IRDJ@117747|Sphingobacteriia 976|Bacteroidetes C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhF - - - - - - - - - - - Molybdopterin,Molydop_binding CMS3_k127_879333_0 1121904.ARBP01000005_gene4600 2.622e-88 301.0 COG1397@1|root,COG1397@2|Bacteria,4NISQ@976|Bacteroidetes,47U70@768503|Cytophagia 976|Bacteroidetes O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH CMS3_k127_879333_1 517418.Ctha_0150 5.743e-59 210.0 COG2353@1|root,COG2353@2|Bacteria,1FF8G@1090|Chlorobi 1090|Chlorobi S Belongs to the UPF0312 family - - - - - - - - - - - - YceI CMS3_k127_883791_8 880070.Cycma_2741 1.05e-25 109.0 COG2937@1|root,COG2937@2|Bacteria,4NK5H@976|Bacteroidetes,47M20@768503|Cytophagia 976|Bacteroidetes I Belongs to the GPAT DAPAT family plsB - 2.3.1.15 ko:K00631 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CMS3_k127_883791_2 1237149.C900_00643 4.256e-127 415.0 COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,47K3D@768503|Cytophagia 976|Bacteroidetes I PFAM NAD-dependent glycerol-3-phosphate dehydrogenase gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N CMS3_k127_883791_4 313606.M23134_00104 3.073e-64 224.0 COG2050@1|root,COG2050@2|Bacteria,4NUVZ@976|Bacteroidetes 976|Bacteroidetes Q Thioesterase superfamily - - - - - - - - - - - - 4HBT CMS3_k127_883791_3 984262.SGRA_0314 9.103e-76 259.0 COG1136@1|root,COG1136@2|Bacteria,4NGDU@976|Bacteroidetes,1IPBQ@117747|Sphingobacteriia 976|Bacteroidetes V Part of the ABC transporter complex LolCDE involved in the translocation of lolD - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran CMS3_k127_883791_7 504487.JCM19302_4 5.329e-46 172.0 COG1595@1|root,COG1595@2|Bacteria,4NNP4@976|Bacteroidetes,1I284@117743|Flavobacteriia 976|Bacteroidetes K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS3_k127_883791_0 525373.HMPREF0766_10955 3.372e-153 489.0 COG0022@1|root,COG0022@2|Bacteria,4NE4N@976|Bacteroidetes,1IPGW@117747|Sphingobacteriia 976|Bacteroidetes C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C CMS3_k127_883791_5 908937.Prede_0168 3.372e-57 207.0 COG0670@1|root,COG0670@2|Bacteria,4NMEV@976|Bacteroidetes,2G38Z@200643|Bacteroidia 976|Bacteroidetes S Belongs to the BI1 family - - - ko:K06890 - - - - ko00000 - - - Bax1-I CMS3_k127_883791_6 1502770.JQMG01000001_gene901 6.979e-56 198.0 COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WHYU@28216|Betaproteobacteria,2KNBE@206350|Nitrosomonadales 206350|Nitrosomonadales T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_883791_1 1121890.AUDO01000005_gene1550 2.501e-133 453.0 COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia,2NUWE@237|Flavobacterium 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg CMS3_k127_88847_19 1356852.N008_00430 4.175e-17 84.0 COG3225@1|root,COG3225@2|Bacteria,4NF62@976|Bacteroidetes,47JZF@768503|Cytophagia 976|Bacteroidetes N ABC transporter substrate-binding component GldG gldG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC_transp_aux CMS3_k127_88847_10 714943.Mucpa_1603 1.978e-77 266.0 COG1277@1|root,COG1277@2|Bacteria,4NG5G@976|Bacteroidetes,1IRI4@117747|Sphingobacteriia 976|Bacteroidetes S TIGRFAM Gliding motility-associated ABC transporter permease protein GldF gldF - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 CMS3_k127_88847_7 1123278.KB893549_gene5164 5.512e-96 323.0 COG1131@1|root,COG1131@2|Bacteria,4NEH0@976|Bacteroidetes,47KF6@768503|Cytophagia 976|Bacteroidetes V TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA gldA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS3_k127_88847_11 1313421.JHBV01000020_gene5288 6.695e-71 262.0 COG0747@1|root,COG0747@2|Bacteria 2|Bacteria E dipeptide transport oppA_5 - - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 CMS3_k127_88847_2 1121904.ARBP01000012_gene1288 8.107e-145 467.0 COG0624@1|root,COG0624@2|Bacteria,4NE2G@976|Bacteroidetes,47KCS@768503|Cytophagia 976|Bacteroidetes E PFAM Peptidase family M20 M25 M40 argE - 3.5.1.16 ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R00669,R09107 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 CMS3_k127_88847_8 999419.HMPREF1077_00944 1.487e-83 285.0 COG0548@1|root,COG0548@2|Bacteria,4NDY8@976|Bacteroidetes,2FN66@200643|Bacteroidia,22VYC@171551|Porphyromonadaceae 976|Bacteroidetes E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase CMS3_k127_88847_5 1121904.ARBP01000004_gene1039 6.48e-130 423.0 COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,47JPH@768503|Cytophagia 976|Bacteroidetes E Belongs to the ATCase OTCase family argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 ko:K09065,ko:K13043 ko00220,ko01100,ko01230,map00220,map01100,map01230 M00845 R07245,R08937 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N CMS3_k127_88847_1 547042.BACCOPRO_03289 1.231e-159 511.0 COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,2FNR5@200643|Bacteroidia,4AKEG@815|Bacteroidaceae 976|Bacteroidetes E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family argD - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CMS3_k127_88847_4 1408473.JHXO01000006_gene1226 1.909e-131 426.0 COG0002@1|root,COG0002@2|Bacteria,4NEQR@976|Bacteroidetes,2FMWZ@200643|Bacteroidia 976|Bacteroidetes E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CMS3_k127_88847_15 421072.IO89_02090 1.394e-44 165.0 COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,1I4E1@117743|Flavobacteriia 976|Bacteroidetes P GxxExxY protein - - - - - - - - - - - - PDDEXK_3 CMS3_k127_88847_0 1121904.ARBP01000004_gene1042 3.903e-191 603.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,47JNE@768503|Cytophagia 976|Bacteroidetes E argininosuccinate synthase argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth CMS3_k127_88847_9 1121930.AQXG01000011_gene1764 4.771e-78 265.0 COG0454@1|root,COG0454@2|Bacteria,4PKZU@976|Bacteroidetes 976|Bacteroidetes K Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 CMS3_k127_88847_12 1121904.ARBP01000001_gene5878 1.264e-51 188.0 COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,47P8B@768503|Cytophagia 976|Bacteroidetes J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase CMS3_k127_88847_14 391596.PBAL39_04703 3.725e-47 171.0 COG1694@1|root,COG1694@2|Bacteria,4NQ3H@976|Bacteroidetes,1IXUY@117747|Sphingobacteriia 976|Bacteroidetes S Phosphoribosyl-ATP pyrophosphohydrolase ypjD - - - - - - - - - - - MazG CMS3_k127_88847_3 1453500.AT05_07060 6.283e-144 465.0 COG0823@1|root,COG0823@2|Bacteria,4PMAE@976|Bacteroidetes,1HWTA@117743|Flavobacteriia 976|Bacteroidetes U Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - PD40 CMS3_k127_88847_17 269798.CHU_2983 3.132e-24 104.0 COG4829@1|root,COG4829@2|Bacteria,4NS7J@976|Bacteroidetes,47RN0@768503|Cytophagia 976|Bacteroidetes Q muconolactone delta-isomerase - - - - - - - - - - - - MIase CMS3_k127_88847_16 1121104.AQXH01000001_gene1190 1.101e-25 111.0 29E7I@1|root,3015I@2|Bacteria,4NNFG@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 CMS3_k127_88847_18 1122179.KB890431_gene4187 8.844e-19 92.0 2EHC3@1|root,33B3Y@2|Bacteria,4NZPQ@976|Bacteroidetes 976|Bacteroidetes S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 CMS3_k127_88847_6 1122179.KB890436_gene1235 2.107e-125 411.0 COG3239@1|root,COG3239@2|Bacteria,4NNB2@976|Bacteroidetes,1IZDH@117747|Sphingobacteriia 976|Bacteroidetes I PFAM Fatty acid desaturase - - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS3_k127_891237_2 1107311.Q767_03065 1.164e-100 338.0 2CSRV@1|root,32SRR@2|Bacteria,4NTI6@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - NlpE CMS3_k127_891237_3 1296415.JACC01000054_gene2912 3.429e-84 287.0 COG0789@1|root,COG0789@2|Bacteria,4PJNN@976|Bacteroidetes,1II2Z@117743|Flavobacteriia,2YKNE@290174|Aquimarina 976|Bacteroidetes K TipAS antibiotic-recognition domain - - - - - - - - - - - - MerR_1,TipAS CMS3_k127_891237_4 313628.LNTAR_01957 3.868e-78 269.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 CMS3_k127_891237_1 1121011.AUCB01000002_gene484 1.016e-102 341.0 COG1082@1|root,COG1082@2|Bacteria,4NHGW@976|Bacteroidetes,1I08E@117743|Flavobacteriia,23GCU@178469|Arenibacter 976|Bacteroidetes G Xylose isomerase-like TIM barrel - - 5.1.3.30,5.1.3.31 ko:K18910 - - R10817,R10818 RC03111,RC03283 ko00000,ko01000 - - - AP_endonuc_2,AP_endonuc_2_N CMS3_k127_891237_0 925409.KI911562_gene245 1.47e-119 387.0 COG0235@1|root,COG0235@2|Bacteria,4NGMP@976|Bacteroidetes,1IPP5@117747|Sphingobacteriia 976|Bacteroidetes G PFAM Class II aldolase adducin araD - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II CMS3_k127_891237_5 385682.AFSL01000039_gene159 1.677e-26 110.0 COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes,2FNNI@200643|Bacteroidia,3XJ4A@558415|Marinilabiliaceae 976|Bacteroidetes C FGGY family of carbohydrate kinases, C-terminal domain araB - 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N CMS3_k127_90095_2 7955.ENSDARP00000074190 7.748e-48 174.0 COG0183@1|root,KOG1392@2759|Eukaryota,38H71@33154|Opisthokonta,3BF43@33208|Metazoa,3CTW5@33213|Bilateria,482H3@7711|Chordata,48WSP@7742|Vertebrata,4A005@7898|Actinopterygii 33208|Metazoa I hydroxyacyl-Coenzyme A dehydrogenase 3-ketoacyl-Coenzyme A thiolase enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit HADHB GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003857,GO:0003988,GO:0004300,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005743,GO:0005759,GO:0005783,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009062,GO:0009295,GO:0009987,GO:0010259,GO:0012505,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016491,GO:0016507,GO:0016508,GO:0016509,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0016829,GO:0016835,GO:0016836,GO:0017076,GO:0019395,GO:0019752,GO:0019866,GO:0019867,GO:0030258,GO:0030554,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0034440,GO:0036094,GO:0036125,GO:0042645,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046395,GO:0048037,GO:0048856,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:0097367,GO:0098588,GO:0098798,GO:0098805,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 2.3.1.16 ko:K07509 ko00062,ko00071,ko00280,ko01100,ko01110,ko01130,ko01212,map00062,map00071,map00280,map01100,map01110,map01130,map01212 M00085,M00087 R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747 RC00004,RC00326,RC00405,RC01702 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N CMS3_k127_90095_0 266117.Rxyl_2453 1.025e-174 571.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2GJ50@201174|Actinobacteria,4CPGR@84995|Rubrobacteria 84995|Rubrobacteria I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 CMS3_k127_90095_1 986075.CathTA2_0543 4.227e-88 331.0 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli 91061|Bacilli L Superfamily I DNA and RNA - - - - - - - - - - - - AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559 CMS3_k127_906434_5 1035193.HMPREF9073_01601 2.535e-07 56.0 COG1669@1|root,COG1669@2|Bacteria,4NV8X@976|Bacteroidetes,1I457@117743|Flavobacteriia,1ES6F@1016|Capnocytophaga 976|Bacteroidetes S Nucleotidyltransferase domain - - - ko:K07075 - - - - ko00000 - - - NTP_transf_2 CMS3_k127_906434_4 63737.Npun_R4744 2.013e-33 150.0 COG0642@1|root,COG0745@1|root,COG2199@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HISH@1161|Nostocales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg CMS3_k127_906434_3 929562.Emtol_1087 9.345e-40 170.0 COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,47KG1@768503|Cytophagia 976|Bacteroidetes T PFAM Two component regulator propeller - - - - - - - - - - - - Reg_prop,YceI CMS3_k127_906434_0 313596.RB2501_04010 3.968e-136 452.0 COG2114@1|root,COG2114@2|Bacteria,4PMA6@976|Bacteroidetes,1IJPA@117743|Flavobacteriia 976|Bacteroidetes T GAF domain - - - - - - - - - - - - GAF_3,Guanylate_cyc CMS3_k127_906434_1 1121875.KB907549_gene1769 1.475e-50 182.0 COG0745@1|root,COG0745@2|Bacteria,4NVP7@976|Bacteroidetes,1I5B4@117743|Flavobacteriia 976|Bacteroidetes T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_906434_2 272134.KB731324_gene2090 2.977e-43 160.0 COG0745@1|root,COG0745@2|Bacteria,1G5XG@1117|Cyanobacteria,1HB6Y@1150|Oscillatoriales 1117|Cyanobacteria T Response regulator receiver domain - - - - - - - - - - - - Response_reg CMS3_k127_911529_2 525373.HMPREF0766_10835 1.026e-100 341.0 COG0770@1|root,COG0770@2|Bacteria,4NDWD@976|Bacteroidetes,1IQA5@117747|Sphingobacteriia 976|Bacteroidetes M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS3_k127_911529_0 1313421.JHBV01000039_gene2760 8.988e-117 403.0 COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes 976|Bacteroidetes Q PFAM FG-GAP repeat - - - - - - - - - - - - VCBS CMS3_k127_911529_1 1121904.ARBP01000001_gene5951 3.878e-110 364.0 COG0491@1|root,COG0491@2|Bacteria,4NHXR@976|Bacteroidetes,47NQG@768503|Cytophagia 976|Bacteroidetes S Metallo-beta-lactamase superfamily - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B CMS3_k127_911529_3 1454007.JAUG01000009_gene2005 9.903e-66 231.0 COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,1IQTK@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 CMS3_k127_92121_4 643867.Ftrac_3317 2.942e-30 126.0 COG5343@1|root,COG5343@2|Bacteria,4NI2H@976|Bacteroidetes,47M55@768503|Cytophagia 976|Bacteroidetes S PFAM Anti-sigma-K factor RskA - - - - - - - - - - - - RskA CMS3_k127_92121_3 1121904.ARBP01000005_gene4850 1.914e-117 383.0 COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,47KF3@768503|Cytophagia 976|Bacteroidetes G Haloacid dehalogenase-like hydrolase - - - ko:K02566 - - - - ko00000 - - - Hydrolase_6,Hydrolase_like CMS3_k127_92121_0 262724.TT_C0602 1.509e-185 589.0 COG1541@1|root,COG1541@2|Bacteria,1WJ2G@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006082,GO:0006725,GO:0006805,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019439,GO:0019748,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0047475,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0097367,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 CMS3_k127_92121_1 929556.Solca_4227 2.22e-171 549.0 COG0124@1|root,COG0124@2|Bacteria,4NE8N@976|Bacteroidetes,1IQNJ@117747|Sphingobacteriia 976|Bacteroidetes J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His CMS3_k127_92121_2 1123234.AUKI01000017_gene2539 1.871e-124 406.0 COG0330@1|root,COG0330@2|Bacteria,4NEP5@976|Bacteroidetes,1HWKG@117743|Flavobacteriia 976|Bacteroidetes O Membrane protease subunits, stomatin prohibitin homologs - - - - - - - - - - - - Band_7 CMS3_k127_924912_0 929556.Solca_4039 4.429e-167 535.0 COG0151@1|root,COG0151@2|Bacteria,4NEUN@976|Bacteroidetes,1IPBB@117747|Sphingobacteriia 976|Bacteroidetes F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N CMS3_k127_924912_1 1121904.ARBP01000009_gene4339 5.058e-112 375.0 COG0526@1|root,COG0526@2|Bacteria,4PMB3@976|Bacteroidetes,47JVX@768503|Cytophagia 976|Bacteroidetes CO Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin CMS3_k127_924912_2 880070.Cycma_0185 2.737e-48 175.0 COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,47JA6@768503|Cytophagia 976|Bacteroidetes F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK CMS3_k127_934074_0 1123248.KB893314_gene3574 5.414e-38 148.0 COG1595@1|root,COG1595@2|Bacteria,4NIB5@976|Bacteroidetes,1IT9A@117747|Sphingobacteriia 976|Bacteroidetes K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - - - - - - - - - - Sigma70_r2 CMS3_k127_935096_3 1550091.JROE01000008_gene3696 1.193e-31 134.0 28HE2@1|root,2Z7QJ@2|Bacteria,4NFBA@976|Bacteroidetes,1INW8@117747|Sphingobacteriia 976|Bacteroidetes S Domain of unknown function (DUF5103) - - - - - - - - - - - - DUF5103 CMS3_k127_935096_2 984262.SGRA_2533 7.638e-59 224.0 COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1IQZU@117747|Sphingobacteriia 976|Bacteroidetes E Peptidase M1 - - 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M1 CMS3_k127_935096_0 1121346.KB899813_gene2173 2.815e-116 387.0 COG1820@1|root,COG1820@2|Bacteria,1UXPG@1239|Firmicutes,4HC0A@91061|Bacilli,26TCN@186822|Paenibacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family - - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 CMS3_k127_935096_1 1449063.JMLS01000009_gene2349 9.327e-77 266.0 COG0363@1|root,COG0363@2|Bacteria,1V1UT@1239|Firmicutes,4HFPX@91061|Bacilli,26R90@186822|Paenibacillaceae 91061|Bacilli G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase - - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso CMS3_k127_935096_4 1121904.ARBP01000019_gene2758 1.804e-26 113.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,47JQC@768503|Cytophagia 976|Bacteroidetes DM TIGRFAM capsular exopolysaccharide family - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz CMS3_k127_947316_5 926561.KB900617_gene2102 6.976e-08 58.0 COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,25EAY@186801|Clostridia,3WBCZ@53433|Halanaerobiales 186801|Clostridia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 CMS3_k127_947316_2 1121904.ARBP01000005_gene4622 7.604e-93 313.0 COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,47XHY@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - ko:K12984 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.1.3 GT2 - Glycos_transf_2 CMS3_k127_947316_1 1313421.JHBV01000031_gene1415 8.856e-158 511.0 COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1IPRW@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C CMS3_k127_947316_3 1189612.A33Q_1863 2.218e-31 124.0 COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,47R56@768503|Cytophagia 976|Bacteroidetes IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS3_k127_947316_0 553178.CAPGI0001_0538 1.228e-179 570.0 COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,1HWXE@117743|Flavobacteriia,1EQYB@1016|Capnocytophaga 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS3_k127_947316_4 1313421.JHBV01000024_gene5033 3.947e-18 87.0 COG0571@1|root,COG0571@2|Bacteria,4NE0N@976|Bacteroidetes,1IPYG@117747|Sphingobacteriia 976|Bacteroidetes K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm CMS3_k127_952617_2 886379.AEWI01000052_gene2660 8.442e-22 98.0 COG1373@1|root,COG1373@2|Bacteria,4NE3E@976|Bacteroidetes,2FP33@200643|Bacteroidia 976|Bacteroidetes S Psort location Cytoplasmic, score 8.96 - - - ko:K07133 - - - - ko00000 - - - AAA_14 CMS3_k127_952617_1 926559.JoomaDRAFT_0843 5.074e-85 289.0 COG1484@1|root,COG1484@2|Bacteria,4NFE0@976|Bacteroidetes,1HYB4@117743|Flavobacteriia 976|Bacteroidetes L PFAM IstB-like ATP binding protein - - - - - - - - - - - - IstB_IS21 CMS3_k127_952617_0 926559.JoomaDRAFT_2303 2.351e-156 509.0 COG4584@1|root,COG4584@2|Bacteria,4NEY6@976|Bacteroidetes,1HYXS@117743|Flavobacteriia 976|Bacteroidetes L Integrase core domain - - - - - - - - - - - - HTH_11,HTH_23,rve CMS3_k127_957383_1 391587.KAOT1_13667 3.648e-154 494.0 COG2378@1|root,COG2378@2|Bacteria,4NGHM@976|Bacteroidetes,1HY66@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - - - - - - - - - - PhyH,WYL CMS3_k127_957383_0 755732.Fluta_0555 0.0 1023.0 COG2310@1|root,COG2310@2|Bacteria,4NHX3@976|Bacteroidetes,1I0QI@117743|Flavobacteriia,2PBI9@246874|Cryomorphaceae 976|Bacteroidetes T Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - - CMS3_k127_957383_2 1121438.JNJA01000001_gene2560 3.288e-06 57.0 COG0785@1|root,COG2319@1|root,COG0785@2|Bacteria,COG2319@2|Bacteria 2|Bacteria S anaphase-promoting complex binding mauF - 2.7.11.1 ko:K03466,ko:K06196,ko:K12132 - - - - ko00000,ko01000,ko01001,ko02000,ko03036 3.A.12,5.A.1.2 - - AAA_16,Trans_reg_C,WD40 CMS3_k127_966079_1 485918.Cpin_0165 2.152e-108 358.0 COG2256@1|root,COG2256@2|Bacteria,4NEV8@976|Bacteroidetes,1IPEJ@117747|Sphingobacteriia 976|Bacteroidetes L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase ycaJ - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CMS3_k127_966079_0 382464.ABSI01000013_gene1915 1.044e-136 445.0 2C57D@1|root,2Z7RS@2|Bacteria,46XDH@74201|Verrucomicrobia,2IVJC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF2891) - - - - - - - - - - - - DUF2891 CMS3_k127_966079_4 1229780.BN381_130193 0.0003196 46.0 2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria 201174|Actinobacteria S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N,SHOCT CMS3_k127_966079_2 1121373.KB903663_gene1025 7.633e-56 216.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,4NHG0@976|Bacteroidetes,47JZ1@768503|Cytophagia 976|Bacteroidetes M PFAM Transglycosylase SLT domain - - - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS3_k127_966079_3 1122931.AUAE01000009_gene4737 9.428e-35 135.0 COG4122@1|root,COG4122@2|Bacteria,4NH42@976|Bacteroidetes,2FM5S@200643|Bacteroidia,22WC1@171551|Porphyromonadaceae 976|Bacteroidetes S O-Methyltransferase - - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 CMS3_k127_968646_6 927658.AJUM01000042_gene1692 9.502e-09 60.0 COG0204@1|root,COG0204@2|Bacteria,4NQF1@976|Bacteroidetes,2FXSZ@200643|Bacteroidia 976|Bacteroidetes I Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase CMS3_k127_968646_7 926562.Oweho_2294 1.262e-08 56.0 COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1HZR2@117743|Flavobacteriia 976|Bacteroidetes S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt CMS3_k127_968646_0 760192.Halhy_4720 4.816e-136 446.0 COG4690@1|root,COG4690@2|Bacteria 2|Bacteria E dipeptidase activity - - - ko:K14358 - - - - ko00000,ko01002 - - - AAT,Peptidase_C69 CMS3_k127_968646_4 1408473.JHXO01000011_gene3022 7.329e-41 169.0 2DB82@1|root,2Z7PX@2|Bacteria,4NEW5@976|Bacteroidetes,2FMDV@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - Beta_helix CMS3_k127_968646_1 714943.Mucpa_1239 1.273e-87 301.0 COG1215@1|root,COG1215@2|Bacteria,4NF08@976|Bacteroidetes,1IR08@117747|Sphingobacteriia 976|Bacteroidetes M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS3_k127_968646_3 1124780.ANNU01000005_gene2339 5.656e-46 173.0 COG2324@1|root,COG2324@2|Bacteria,4NQR7@976|Bacteroidetes,47QH8@768503|Cytophagia 976|Bacteroidetes S Carotenoid biosynthesis protein - - - - - - - - - - - - Caroten_synth CMS3_k127_968646_5 1121904.ARBP01000006_gene3907 5.853e-15 82.0 COG3637@1|root,COG3637@2|Bacteria,4NYY3@976|Bacteroidetes 976|Bacteroidetes M Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl,OMP_b-brl_2 CMS3_k127_968646_2 700598.Niako_6385 3.312e-69 239.0 COG0252@1|root,COG0252@2|Bacteria,4NRB3@976|Bacteroidetes,1IXAX@117747|Sphingobacteriia 976|Bacteroidetes EJ Asparaginase, N-terminal - - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase CMS3_k127_968646_8 709991.Odosp_3204 1.975e-05 47.0 COG4591@1|root,COG4591@2|Bacteria,4NFWZ@976|Bacteroidetes,2FMHC@200643|Bacteroidia,22WJ1@171551|Porphyromonadaceae 976|Bacteroidetes M ABC transporter permease lolE_1 - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD CMS3_k127_972512_0 760192.Halhy_2973 9.191e-239 775.0 COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NDXU@976|Bacteroidetes 976|Bacteroidetes T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,Reg_prop,Response_reg,Y_Y_Y CMS3_k127_972512_2 1121904.ARBP01000004_gene969 5.677e-90 305.0 COG2017@1|root,COG2017@2|Bacteria,4NE32@976|Bacteroidetes,47KZH@768503|Cytophagia 976|Bacteroidetes G converts alpha-aldose to the beta-anomer - - - - - - - - - - - - - CMS3_k127_972512_3 468059.AUHA01000002_gene1223 2.958e-07 60.0 COG2353@1|root,COG2911@1|root,COG2353@2|Bacteria,COG2911@2|Bacteria,4PN0F@976|Bacteroidetes,1IWTM@117747|Sphingobacteriia 976|Bacteroidetes P major pilin protein fima - - - - - - - - - - - - LTD,Laminin_G_3 CMS3_k127_972512_1 1296416.JACB01000051_gene2674 1.196e-179 569.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,1HWV4@117743|Flavobacteriia,2YJ0Z@290174|Aquimarina 976|Bacteroidetes I Acyl-CoA dehydrogenase, N-terminal domain acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS3_k127_979820_0 1122176.KB903609_gene5145 4.929e-104 342.0 COG0177@1|root,COG0177@2|Bacteria,4NFF3@976|Bacteroidetes,1IPXY@117747|Sphingobacteriia 976|Bacteroidetes L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD CMS3_k127_979820_3 1121904.ARBP01000010_gene2314 5.58e-45 172.0 COG0457@1|root,COG0457@2|Bacteria,4PN8J@976|Bacteroidetes,47YES@768503|Cytophagia 976|Bacteroidetes S Protein of unknown function (DUF2911) - - - - - - - - - - - - DUF2911 CMS3_k127_979820_1 926549.KI421517_gene1122 2.389e-90 310.0 28I3N@1|root,2Z87C@2|Bacteria,4NE8P@976|Bacteroidetes,47M50@768503|Cytophagia 976|Bacteroidetes S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 CMS3_k127_979820_2 1122605.KB893627_gene2980 4.125e-46 168.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,1IPXI@117747|Sphingobacteriia 976|Bacteroidetes G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI CMS3_k127_988985_0 886379.AEWI01000004_gene900 5.42e-265 833.0 COG0587@1|root,COG0587@2|Bacteria,4NE2R@976|Bacteroidetes,2FW95@200643|Bacteroidia,3XIXS@558415|Marinilabiliaceae 976|Bacteroidetes L DNA polymerase alpha chain like domain - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP CMS3_k127_988985_1 388413.ALPR1_16264 5.239e-138 449.0 COG0389@1|root,COG0389@2|Bacteria,4NE9N@976|Bacteroidetes,47JI6@768503|Cytophagia 976|Bacteroidetes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH CMS3_k127_988985_4 760192.Halhy_1384 0.0001056 46.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH,HNH_5 CMS3_k127_988985_3 395961.Cyan7425_2749 7.86e-08 59.0 2B8AH@1|root,321J4@2|Bacteria,1GMJZ@1117|Cyanobacteria,3KKHC@43988|Cyanothece 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS3_k127_988985_2 1123276.KB893246_gene643 6.127e-66 232.0 COG1216@1|root,COG1216@2|Bacteria,4NETR@976|Bacteroidetes,47MJC@768503|Cytophagia 976|Bacteroidetes M Glycosyl transferase family 2 - - - - - - - - - - - - DUF2062,Glycos_transf_2 CMS3_k127_98939_0 1123278.KB893611_gene4436 1.205e-55 198.0 COG2382@1|root,COG2382@2|Bacteria,4NK15@976|Bacteroidetes,47MMH@768503|Cytophagia 976|Bacteroidetes P Putative esterase - - - ko:K07214 - - - - ko00000 - - - Esterase,SGL CMS3_k127_98939_3 909663.KI867150_gene2332 2.241e-34 134.0 COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,42STH@68525|delta/epsilon subdivisions,2WP6X@28221|Deltaproteobacteria,2MSFP@213462|Syntrophobacterales 28221|Deltaproteobacteria L PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin CMS3_k127_98939_4 1123057.P872_13040 1.125e-19 91.0 2EEZ4@1|root,30XX1@2|Bacteria,4PBHB@976|Bacteroidetes,47VW5@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_98939_1 1121875.KB907547_gene3395 7.97e-47 170.0 2AFVV@1|root,315YK@2|Bacteria,4NQ4S@976|Bacteroidetes,1I2VI@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS3_k127_98939_2 641524.ADICYQ_1996 1.916e-44 173.0 COG3618@1|root,COG3618@2|Bacteria,4P1FE@976|Bacteroidetes,47UAG@768503|Cytophagia 976|Bacteroidetes S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS3_k127_98939_5 443598.AUFA01000054_gene3458 7.518e-15 74.0 COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,3JWM1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4172) - - - - - - - - - - - - DUF4172,Fic CMS3_k127_994052_4 1166018.FAES_1497 1.417e-26 109.0 COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,47M9C@768503|Cytophagia 976|Bacteroidetes S Oxidoreductase domain protein - - - - - - - - - - - - GFO_IDH_MocA CMS3_k127_994052_3 1121904.ARBP01000005_gene4832 1.097e-77 268.0 COG2133@1|root,COG2133@2|Bacteria,4NIQ7@976|Bacteroidetes,47K6E@768503|Cytophagia 976|Bacteroidetes G Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS3_k127_994052_0 1121904.ARBP01000026_gene688 7.871e-179 564.0 COG0620@1|root,COG0620@2|Bacteria,4NF5S@976|Bacteroidetes,47NU3@768503|Cytophagia 976|Bacteroidetes E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS3_k127_994052_2 1121904.ARBP01000026_gene687 9.881e-118 386.0 COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia 976|Bacteroidetes S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 CMS3_k127_994052_1 1250232.JQNJ01000001_gene3718 8.034e-157 507.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1HZ0Y@117743|Flavobacteriia 976|Bacteroidetes EU peptidase - - - - - - - - - - - - PD40,Peptidase_S9 CMS3_k127_994461_2 929562.Emtol_2430 2.472e-101 341.0 COG0612@1|root,COG0612@2|Bacteria,4NEE4@976|Bacteroidetes,47JFQ@768503|Cytophagia 976|Bacteroidetes S PFAM Peptidase M16 inactive domain - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CMS3_k127_994461_1 1122621.ATZA01000002_gene1586 7.093e-149 481.0 COG0420@1|root,COG0420@2|Bacteria,4NEET@976|Bacteroidetes,1IPQS@117747|Sphingobacteriia 976|Bacteroidetes L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C CMS3_k127_994461_0 313606.M23134_06631 1.427e-161 543.0 COG0419@1|root,COG0419@2|Bacteria,4NH9H@976|Bacteroidetes,47N6H@768503|Cytophagia 976|Bacteroidetes L ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,SbcCD_C ## 5294 queries scanned ## Total time (seconds): 333.67881298065186 ## Rate: 15.87 q/s